1 hsa-let-7a-1 Colonic Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 2 hsa-let-7a-1 Heart Failure 17606841 upregulated 3 hsa-let-7a-1 Lung Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 4 hsa-let-7a-1 Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. 5 hsa-let-7a-1 Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. 6 hsa-let-7a-1 Lung Neoplasms 16712479 downregulation 7 hsa-let-7a-1 Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. 8 hsa-let-7a-1 Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients 9 hsa-let-7a-1 Lung Neoplasms 15172979 reduced expression 10 hsa-let-7a-1 Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 11 hsa-let-7a-1 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 12 hsa-let-7a-1 Neoplasms 17028596 let-7a-1 downregulated in six solid cancer types by PAM and SAM (Volinia et al., 2006); 13 hsa-let-7a-1 Neoplasms 17028596 Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control. 14 hsa-let-7a-2 Breast Neoplasms 17028596 let-7a-2, 7a-3, 7d, 7f-2 downregulated in breast cancer 15 hsa-let-7a-2 Colonic Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 16 hsa-let-7a-2 Heart Failure 17606841 upregulated 17 hsa-let-7a-2 Lung Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 18 hsa-let-7a-2 Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. 19 hsa-let-7a-2 Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. 20 hsa-let-7a-2 Lung Neoplasms 16712479 downregulation 21 hsa-let-7a-2 Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. 22 hsa-let-7a-2 Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients 23 hsa-let-7a-2 Lung Neoplasms 15172979 reduced expression 24 hsa-let-7a-2 Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 25 hsa-let-7a-2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 26 hsa-let-7a-2 Neoplasms 17028596 Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control. 27 hsa-let-7a-3 Breast Neoplasms 17028596 let-7a-2, 7a-3, 7d, 7f-2 downregulated in breast cancer 28 hsa-let-7a-3 Colonic Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 29 hsa-let-7a-3 Lung Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 30 hsa-let-7a-3 Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. 31 hsa-let-7a-3 Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. 32 hsa-let-7a-3 Lung Neoplasms 16712479 downregulation 33 hsa-let-7a-3 Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. 34 hsa-let-7a-3 Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients 35 hsa-let-7a-3 Lung Neoplasms 15172979 reduced expression 36 hsa-let-7a-3 Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 37 hsa-let-7a-3 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 38 hsa-let-7a-3 Neoplasms 17028596 Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control. 39 hsa-let-7b Colonic Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 40 hsa-let-7b Heart Failure 17606841 upregulated 41 hsa-let-7b Lung Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 42 hsa-let-7b Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. 43 hsa-let-7b Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. 44 hsa-let-7b Lung Neoplasms 16712479 downregulation 45 hsa-let-7b Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. 46 hsa-let-7b Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients 47 hsa-let-7b Lung Neoplasms 15172979 reduced expression 48 hsa-let-7b Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 49 hsa-let-7b Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 50 hsa-let-7b Neoplasms 17028596 Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control. 51 hsa-let-7c Colonic Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 52 hsa-let-7c Heart Failure 17606841 upregulated 53 hsa-let-7c Lung Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 54 hsa-let-7c Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. 55 hsa-let-7c Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. 56 hsa-let-7c Lung Neoplasms 16712479 downregulation 57 hsa-let-7c Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. 58 hsa-let-7c Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients 59 hsa-let-7c Lung Neoplasms 15172979 reduced expression 60 hsa-let-7c Muscular Disorders, Atrophic 17942673 dysregulation 61 hsa-let-7c Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 62 hsa-let-7c Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 63 hsa-let-7c Neoplasms 17028596 Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control. 64 hsa-let-7d Breast Neoplasms 17028596 let-7a-2, 7a-3, 7d, 7f-2 downregulated in breast cancer 65 hsa-let-7d Colonic Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 66 hsa-let-7d Heart Failure 17606841 upregulated 67 hsa-let-7d Lung Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 68 hsa-let-7d Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. 69 hsa-let-7d Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. 70 hsa-let-7d Lung Neoplasms 16712479 downregulation 71 hsa-let-7d Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. 72 hsa-let-7d Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients 73 hsa-let-7d Lung Neoplasms 15172979 reduced expression 74 hsa-let-7d Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 75 hsa-let-7d Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 76 hsa-let-7d Neoplasms 17028596 Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control. 77 hsa-let-7e Carcinoma, Hepatocellular 17188425 Independent observations showed that the expression of miRNAs let-7e, 125a and 99b, located at 19q13.4, were considerably lower in HCC compared to nontumor liver [59] and [65]. Given that miRNA-125a targets expression of the mitochondrial tumor suppressor gene, MTSG1, and RAR|á, chromosomal instability in and around FRA19A may extinguish expression of these tumor suppressor genes. 78 hsa-let-7e Colonic Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 79 hsa-let-7e Heart Failure 17606841 upregulated 80 hsa-let-7e Lung Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 81 hsa-let-7e Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. 82 hsa-let-7e Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. 83 hsa-let-7e Lung Neoplasms 16712479 downregulation 84 hsa-let-7e Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. 85 hsa-let-7e Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients 86 hsa-let-7e Lung Neoplasms 15172979 reduced expression 87 hsa-let-7e Muscular Disorders, Atrophic 17942673 dysregulation 88 hsa-let-7e Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 89 hsa-let-7e Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 90 hsa-let-7e Neoplasms 17028596 Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control. 91 hsa-let-7f-1 Colonic Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 92 hsa-let-7f-1 Heart Failure 17606841 upregulated 93 hsa-let-7f-1 Lung Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 94 hsa-let-7f-1 Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. 95 hsa-let-7f-1 Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. 96 hsa-let-7f-1 Lung Neoplasms 16712479 downregulation 97 hsa-let-7f-1 Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. 98 hsa-let-7f-1 Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients 99 hsa-let-7f-1 Lung Neoplasms 15172979 reduced expression 100 hsa-let-7f-1 Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 101 hsa-let-7f-1 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 102 hsa-let-7f-1 Neoplasms 17028596 Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control. 103 hsa-let-7f-2 Breast Neoplasms 17028596 let-7a-2, 7a-3, 7d, 7f-2 downregulated in breast cancer 104 hsa-let-7f-2 Colonic Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 105 hsa-let-7f-2 Heart Failure 17606841 upregulated 106 hsa-let-7f-2 Lung Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 107 hsa-let-7f-2 Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. 108 hsa-let-7f-2 Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. 109 hsa-let-7f-2 Lung Neoplasms 16712479 downregulation 110 hsa-let-7f-2 Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. 111 hsa-let-7f-2 Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients 112 hsa-let-7f-2 Lung Neoplasms 15172979 reduced expression 113 hsa-let-7f-2 Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 114 hsa-let-7f-2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 115 hsa-let-7f-2 Neoplasms 17028596 Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control. 116 hsa-let-7g Colonic Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 117 hsa-let-7g Lung Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 118 hsa-let-7g Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. 119 hsa-let-7g Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. 120 hsa-let-7g Lung Neoplasms 16712479 downregulation 121 hsa-let-7g Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. 122 hsa-let-7g Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients 123 hsa-let-7g Lung Neoplasms 15172979 reduced expression 124 hsa-let-7g Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 125 hsa-let-7g Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 126 hsa-let-7g Neoplasms 17028596 Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control. 127 hsa-let-7i Colonic Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 128 hsa-let-7i Lung Neoplasms 17965831 Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers. 129 hsa-let-7i Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. 130 hsa-let-7i Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. 131 hsa-let-7i Lung Neoplasms 16712479 downregulation 132 hsa-let-7i Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. 133 hsa-let-7i Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients 134 hsa-let-7i Lung Neoplasms 15172979 reduced expression 135 hsa-let-7i Muscular Disorders, Atrophic 17942673 dysregulation 136 hsa-let-7i Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 137 hsa-let-7i Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 138 hsa-let-7i Neoplasms 17028596 Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control. 139 hsa-mir-100 Muscular Disorders, Atrophic 17942673 dysregulation 140 hsa-mir-101-1 Lung Neoplasms 16530703 downregulation 141 hsa-mir-103a-1 Muscular Disorders, Atrophic 17942673 dysregulation 142 hsa-mir-103a-1 Myotonic Dystrophy 17697356 These results support a role for miRNAs in DM1 pathogenesis, and, in particular, highlight mir-107 and mir-103 as attractive candidates for binding to DMPK. 143 hsa-mir-103a-2 Muscular Disorders, Atrophic 17942673 dysregulation 144 hsa-mir-103a-2 Myotonic Dystrophy 17697356 These results support a role for miRNAs in DM1 pathogenesis, and, in particular, highlight mir-107 and mir-103 as attractive candidates for binding to DMPK. 145 hsa-mir-106a Colonic Neoplasms 17442096 Indeed, in human solid tumors, mir-106a expression is increased in colon, pancreas, and prostate tumors. 146 hsa-mir-106a Colonic Neoplasms 16461460 overexpressed 147 hsa-mir-106a Lung Neoplasms 16530703 upregulation 148 hsa-mir-106a Pancreatic Neoplasms 16461460 overexpressed 149 hsa-mir-106a Pancreatic Neoplasms 17442096 Indeed, in human solid tumors, mir-106a expression is increased in colon, pancreas, and prostate tumors. 150 hsa-mir-106a Prostatic Neoplasms 17442096 Indeed, in human solid tumors, mir-106a expression is increased in colon, pancreas, and prostate tumors. 151 hsa-mir-106a Prostatic Neoplasms 16461460 overexpressed 152 hsa-mir-106b Heart Failure 17606841 upregulated 153 hsa-mir-106b Schizophrenia 17326821 upregulation 154 hsa-mir-107 Colonic Neoplasms 16461460 overexpressed 155 hsa-mir-107 Heart Failure 17606841 downregulated 156 hsa-mir-107 Muscular Disorders, Atrophic 17942673 dysregulation 157 hsa-mir-107 Myotonic Dystrophy 17697356 These results support a role for miRNAs in DM1 pathogenesis, and, in particular, highlight mir-107 and mir-103 as attractive candidates for binding to DMPK. 158 hsa-mir-107 Pancreatic Neoplasms 16461460 overexpressed 159 hsa-mir-107 Stomach Neoplasms 16461460 overexpressed 160 hsa-mir-10b Breast Neoplasms 17028596 mir-10b downregulated in breast cancer (Iorio et al., 2005); 161 hsa-mir-10b Breast Neoplasms 16466964 down-regulated 162 hsa-mir-10b Heart Failure 17606841 upregulated 163 hsa-mir-1-1 Arrhythmias, Cardiac 17786230 the finding that increasing or decreasing miR-1 expression causes lethal cardiac arrhythmias highlights not only the exquisite sensitivity of the heart to the levels of expression of this miRNA but also poses significant hurdles to the possible therapeutic manipulation of miR-1 levels in the settings of cardiac conduction abnormalities or myocardial repair. 164 hsa-mir-1-1 Arrhythmias, Cardiac 17401374 These data strongly indicate that miR-1 is an arrhythmogenic or proarrhythmic factor that is detrimental to the ischemic heart. Delivery of miR-1 into healthy hearts was also arrhythmogenic. 165 hsa-mir-1-1 Cardiomyopathy, Hypertrophic 17234972 Significantly,the muscle-specific microRNA-1 (miR-1) was singularly downregulatedas early as day 1, persisting through day7, after aortic constriction Cinduced hypertrophy in a mouse model. 166 hsa-mir-1-1 Cardiomyopathy, Hypertrophic 17479098 The researchers showed that expression of miR-1 and another muscle-specific miRNA, miR-133, is decreased in human and mouse hypertrophic heart tissue. 167 hsa-mir-1-1 Cardiomyopathy, Hypertrophic 17468766 downregulation 168 hsa-mir-1-1 Cardiomyopathy, Hypertrophic 17965831 miR-1 is overexpressed in patients with coronary artery disease and that overexpression of miR-1 in a rat model of cardiac infarction exacerbated arrhythmogenesis. Cardiac hypertrophy may also be regulated by miR-1, which is significantly down-regulated in hypertrophic tissue. 169 hsa-mir-1-1 Cardiomyopathy, Hypertrophic 17468766 We found that miR-133 expression in diseased ventricles and atria was reduced by 50% compared to that in controls. We observed a similar expression pattern for miR-1. Taken together, the murine and human data indicate an inverse correlation between miR-133 and miR-1 expression and myocardial hypertrophy. 170 hsa-mir-1-1 Coronary Artery Disease 17965831 miR-1 is overexpressed in patients with coronary artery disease and that overexpression of miR-1 in a rat model of cardiac infarction exacerbated arrhythmogenesis. Cardiac hypertrophy may also be regulated by miR-1, which is significantly down-regulated in hypertrophic tissue. 171 hsa-mir-1-1 Coronary Artery Disease 17919180 elevated expression 172 hsa-mir-1-1 Coronary Artery Disease 17401374 overexpressed 173 hsa-mir-1-1 Heart Failure 17606841 upregulated 174 hsa-mir-1-1 Musculoskeletal Abnormalities 17917533 Studies performed to determine whether skeletal muscle hypertrophy affects miRNA expression showed that miR-1 and miR-133 were decreased, suggesting that these muscle-specific miRNAs may contribute to regulating the initial response of skeletal muscle to functional overload. 175 hsa-mir-1-2 Arrhythmias, Cardiac 17786230 the finding that increasing or decreasing miR-1 expression causes lethal cardiac arrhythmias highlights not only the exquisite sensitivity of the heart to the levels of expression of this miRNA but also poses significant hurdles to the possible therapeutic manipulation of miR-1 levels in the settings of cardiac conduction abnormalities or myocardial repair. 176 hsa-mir-1-2 Arrhythmias, Cardiac 17401374 These data strongly indicate that miR-1 is an arrhythmogenic or proarrhythmic factor that is detrimental to the ischemic heart. Delivery of miR-1 into healthy hearts was also arrhythmogenic. 177 hsa-mir-1-2 Cardiomyopathy, Hypertrophic 17234972 Significantly,the muscle-specific microRNA-1 (miR-1) was singularly downregulatedas early as day 1, persisting through day7, after aortic constriction Cinduced hypertrophy in a mouse model. 178 hsa-mir-1-2 Cardiomyopathy, Hypertrophic 17479098 The researchers showed that expression of miR-1 and another muscle-specific miRNA, miR-133, is decreased in human and mouse hypertrophic heart tissue. 179 hsa-mir-1-2 Cardiomyopathy, Hypertrophic 17468766 downregulation 180 hsa-mir-1-2 Cardiomyopathy, Hypertrophic 17965831 miR-1 is overexpressed in patients with coronary artery disease and that overexpression of miR-1 in a rat model of cardiac infarction exacerbated arrhythmogenesis. Cardiac hypertrophy may also be regulated by miR-1, which is significantly down-regulated in hypertrophic tissue. 181 hsa-mir-1-2 Cardiomyopathy, Hypertrophic 17468766 We found that miR-133 expression in diseased ventricles and atria was reduced by 50% compared to that in controls. We observed a similar expression pattern for miR-1. Taken together, the murine and human data indicate an inverse correlation between miR-133 and miR-1 expression and myocardial hypertrophy. 182 hsa-mir-1-2 Coronary Artery Disease 17965831 miR-1 is overexpressed in patients with coronary artery disease and that overexpression of miR-1 in a rat model of cardiac infarction exacerbated arrhythmogenesis. Cardiac hypertrophy may also be regulated by miR-1, which is significantly down-regulated in hypertrophic tissue. 183 hsa-mir-1-2 Coronary Artery Disease 17919180 elevated expression 184 hsa-mir-1-2 Coronary Artery Disease 17401374 overexpressed 185 hsa-mir-1-2 Heart Defects, Congenital 17397913 deletion 186 hsa-mir-1-2 Heart Failure 17606841 upregulated 187 hsa-mir-1-2 Musculoskeletal Abnormalities 17917533 Studies performed to determine whether skeletal muscle hypertrophy affects miRNA expression showed that miR-1 and miR-133 were decreased, suggesting that these muscle-specific miRNAs may contribute to regulating the initial response of skeletal muscle to functional overload. 188 hsa-mir-122 Carcinoma, Hepatocellular 16777601 inhibite CAT-1 189 hsa-mir-122 Hepatitis 17462786 Although miRNA regulation of cellular target genes through 3??UTR binding seems to be only negative, the hepatitis C virus (HCV) has creatively made use of the liver-specific and abundantly expressed miR-122 to promote viral replication. 190 hsa-mir-122 Hepatitis C 16141076 interaction with non-coding regions of Hepatitis C help its replication 191 hsa-mir-122 Lipid Metabolism Disorders 17965831 Inhibition of miR-122 resulted in decreased levels of cholesterol in the plasma and improved liver function in obese mice. 192 hsa-mir-124-1 Lung Neoplasms 17028596 mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006); 193 hsa-mir-124-2 Lung Neoplasms 17028596 mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006); 194 hsa-mir-124-3 Lung Neoplasms 17028596 mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006); 195 hsa-mir-125a Breast Neoplasms 16103053 downregulation 196 hsa-mir-125a Breast Neoplasms 17028596 mir-125a, b1, b2 downregulated in breast cancer (Iorio et al., 2005); 197 hsa-mir-125a Carcinoma, Hepatocellular 16331254 downregulated 198 hsa-mir-125a Carcinoma, Hepatocellular 17188425 Independent observations showed that the expression of miRNAs let-7e, 125a and 99b, located at 19q13.4, were considerably lower in HCC compared to nontumor liver [59] and [65]. Given that miRNA-125a targets expression of the mitochondrial tumor suppressor gene, MTSG1, and RAR|á, chromosomal instability in and around FRA19A may extinguish expression of these tumor suppressor genes. 199 hsa-mir-125a Heart Failure 17606841 upregulated 200 hsa-mir-125a Lung Neoplasms 16530703 downregulation 201 hsa-mir-125a Muscular Disorders, Atrophic 17942673 dysregulation 202 hsa-mir-125b-1 Breast Neoplasms 16103053 downregulation 203 hsa-mir-125b-1 Breast Neoplasms 17028596 mir-125a, b1, b2 downregulated in breast cancer (Iorio et al., 2005); 204 hsa-mir-125b-1 Breast Neoplasms 16466964 down-regulated 205 hsa-mir-125b-1 Breast Neoplasms 14973191 deletion 206 hsa-mir-125b-1 Dermatitis, Atopic 17622355 The level of this miRNA significantly (p<0.001 for both) decreased both in psoriasis and atopic eczema. 207 hsa-mir-125b-1 Leukemia, B-Cell 16885332 In a precursor B-cell acute lymphoblastic leukemia, an insertion of miR-125b-1 into a rearranged immunoglobulin heavy chain locus was described. 208 hsa-mir-125b-1 Leukemia, B-Cell 17028302 It is of note that insertion of miR-125b-1 into a rearranged immunoglobulin heavy chain gene locus was recently reported in a patient with precursor B-cell acute lymphoblastic leukemia, though the expression miR-125b-1 was not investigated. 209 hsa-mir-125b-1 Lung Neoplasms 14973191 deletion 210 hsa-mir-125b-1 Ovarian Neoplasms 14973191 deletion 211 hsa-mir-125b-1 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 16151463 an insertion of pre-miRNA into the immunoglobulin heavy-chain locus 212 hsa-mir-125b-1 Psoriasis 17622355 The level of this miRNA significantly (p<0.001 for both) decreased both in psoriasis and atopic eczema. 213 hsa-mir-125b-1 Uterine Cervical Neoplasms 14973191 deletion 214 hsa-mir-125b-2 Breast Neoplasms 16103053 downregulation 215 hsa-mir-125b-2 Breast Neoplasms 17028596 mir-125a, b1, b2 downregulated in breast cancer (Iorio et al., 2005); 216 hsa-mir-125b-2 Breast Neoplasms 16466964 down-regulated 217 hsa-mir-125b-2 Dermatitis, Atopic 17622355 The level of this miRNA significantly (p<0.001 for both) decreased both in psoriasis and atopic eczema. 218 hsa-mir-125b-2 Psoriasis 17622355 The level of this miRNA significantly (p<0.001 for both) decreased both in psoriasis and atopic eczema. 219 hsa-mir-126 Heart Failure 17606841 upregulated 220 hsa-mir-126 Heart Failure 17606841 downregulated 221 hsa-mir-126 Hepatitis, Chronic 16331254 downregulated 222 hsa-mir-126 Lung Neoplasms 16530703 downregulation 223 hsa-mir-126 Muscular Disorders, Atrophic 17942673 dysregulation 224 hsa-mir-126 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 17604727 strongly expressed 225 hsa-mir-127 Breast Neoplasms 16766263 upregulation 226 hsa-mir-127 Colonic Neoplasms 17355635 Human miR-127 is embedded in a CpG island and is silenced in several human cancers including bladder, prostate and colon cancer and has been suggested to play a role as a possible tumour suppressor gene. 227 hsa-mir-127 Neoplasms 17012848 For example, mir-127, which is generally expressed in normal cells but absent in cancer cells, was markedly induced after treatment. Intriguingly, a predicted target of mir-127, BCL6, was translationally downregulated after treatment. 228 hsa-mir-127 Prostatic Neoplasms 17355635 Human miR-127 is embedded in a CpG island and is silenced in several human cancers including bladder, prostate and colon cancer and has been suggested to play a role as a possible tumour suppressor gene. 229 hsa-mir-127 Thyroid Neoplasms 17355635 three miRNAs showed significantly more underexpression compared to the other downregulated miRNAs. These miRNAs are as follows mir-127, mir-130a and mir-144. 230 hsa-mir-127 Urinary Bladder Neoplasms 17355635 Human miR-127 is embedded in a CpG island and is silenced in several human cancers including bladder, prostate and colon cancer and has been suggested to play a role as a possible tumour suppressor gene. 231 hsa-mir-128-2 Colonic Neoplasms 16461460 overexpressed 232 hsa-mir-128-2 Lung Neoplasms 16461460 overexpressed 233 hsa-mir-128-2 Pancreatic Neoplasms 16461460 overexpressed 234 hsa-mir-129-2 Heart Failure 17606841 upregulated 235 hsa-mir-130a Heart Failure 17606841 upregulated 236 hsa-mir-130a Muscular Disorders, Atrophic 17942673 dysregulation 237 hsa-mir-130a Thyroid Neoplasms 17355635 three miRNAs showed significantly more underexpression compared to the other downregulated miRNAs. These miRNAs are as follows mir-127, mir-130a and mir-144. 238 hsa-mir-130b Heart Failure 17606841 downregulated 239 hsa-mir-132 Breast Neoplasms 17447837 miR-132, previously shown to be differentially upregulated in six solid cancer types (breast, colon, lung, pancreas, prostate, and stomach carcinomas) 240 hsa-mir-132 Colonic Neoplasms 17447837 miR-132, previously shown to be differentially upregulated in six solid cancer types (breast, colon, lung, pancreas, prostate, and stomach carcinomas) 241 hsa-mir-132 Heart Failure 17606841 upregulated 242 hsa-mir-132 Lung Neoplasms 17447837 miR-132, previously shown to be differentially upregulated in six solid cancer types (breast, colon, lung, pancreas, prostate, and stomach carcinomas) 243 hsa-mir-132 Muscular Disorders, Atrophic 17942673 dysregulation 244 hsa-mir-132 Pancreatic Neoplasms 17447837 miR-132, previously shown to be differentially upregulated in six solid cancer types (breast, colon, lung, pancreas, prostate, and stomach carcinomas) 245 hsa-mir-132 Prostatic Neoplasms 17447837 miR-132, previously shown to be differentially upregulated in six solid cancer types (breast, colon, lung, pancreas, prostate, and stomach carcinomas) 246 hsa-mir-132 Stomach Neoplasms 17447837 miR-132, previously shown to be differentially upregulated in six solid cancer types (breast, colon, lung, pancreas, prostate, and stomach carcinomas) 247 hsa-mir-133a-1 Arrhythmias, Cardiac 17786230 These results suggest an active role for miR-133 in the inhibition of cardiac hypertrophy. Xiao et al. reported miR-133 to play a role in cardiac conductance abnormalities during diabetes by lowering the protein levels of ether-a-go-go¨Crelated gene (ERG), which encodes a key K+ channel (IKr) responsible for rapid delayed rectifier K+ current in cardiac cells. 248 hsa-mir-133a-1 Arrhythmias, Cardiac 17965831 miR-133 was shown to inhibit the expression of ERG (ether-a-go-go-related gene) and cause depression of the potassium channel I(Kr). This inhibition contributed to long QT syndrome and arrhythmia in a diabetic rat model. 249 hsa-mir-133a-1 Cardiomyopathy, Hypertrophic 17786230 These results suggest an active role for miR-133 in the inhibition of cardiac hypertrophy. Xiao et al. reported miR-133 to play a role in cardiac conductance abnormalities during diabetes by lowering the protein levels of ether-a-go-go¨Crelated gene (ERG), which encodes a key K+ channel (IKr) responsible for rapid delayed rectifier K+ current in cardiac cells. 250 hsa-mir-133a-1 Cardiomyopathy, Hypertrophic 17479098 The researchers showed that expression of miR-1 and another muscle-specific miRNA, miR-133, is decreased in human and mouse hypertrophic heart tissue. 251 hsa-mir-133a-1 Cardiomyopathy, Hypertrophic 17468766 downregulation 252 hsa-mir-133a-1 Cardiomyopathy, Hypertrophic 17468766 We found that miR-133 expression in diseased ventricles and atria was reduced by 50% compared to that in controls. We observed a similar expression pattern for miR-1. Taken together, the murine and human data indicate an inverse correlation between miR-133 and miR-1 expression and myocardial hypertrophy. 253 hsa-mir-133a-1 Long QT Syndrome 17965831 miR-133 was shown to inhibit the expression of ERG (ether-a-go-go-related gene) and cause depression of the potassium channel I(Kr). This inhibition contributed to long QT syndrome and arrhythmia in a diabetic rat model. 254 hsa-mir-133a-1 Musculoskeletal Abnormalities 17917533 Studies performed to determine whether skeletal muscle hypertrophy affects miRNA expression showed that miR-1 and miR-133 were decreased, suggesting that these muscle-specific miRNAs may contribute to regulating the initial response of skeletal muscle to functional overload. 255 hsa-mir-133a-2 Arrhythmias, Cardiac 17786230 These results suggest an active role for miR-133 in the inhibition of cardiac hypertrophy. Xiao et al. reported miR-133 to play a role in cardiac conductance abnormalities during diabetes by lowering the protein levels of ether-a-go-go¨Crelated gene (ERG), which encodes a key K+ channel (IKr) responsible for rapid delayed rectifier K+ current in cardiac cells. 256 hsa-mir-133a-2 Arrhythmias, Cardiac 17965831 miR-133 was shown to inhibit the expression of ERG (ether-a-go-go-related gene) and cause depression of the potassium channel I(Kr). This inhibition contributed to long QT syndrome and arrhythmia in a diabetic rat model. 257 hsa-mir-133a-2 Cardiomyopathy, Hypertrophic 17786230 These results suggest an active role for miR-133 in the inhibition of cardiac hypertrophy. Xiao et al. reported miR-133 to play a role in cardiac conductance abnormalities during diabetes by lowering the protein levels of ether-a-go-go¨Crelated gene (ERG), which encodes a key K+ channel (IKr) responsible for rapid delayed rectifier K+ current in cardiac cells. 258 hsa-mir-133a-2 Cardiomyopathy, Hypertrophic 17479098 The researchers showed that expression of miR-1 and another muscle-specific miRNA, miR-133, is decreased in human and mouse hypertrophic heart tissue. 259 hsa-mir-133a-2 Cardiomyopathy, Hypertrophic 17468766 downregulation 260 hsa-mir-133a-2 Cardiomyopathy, Hypertrophic 17468766 We found that miR-133 expression in diseased ventricles and atria was reduced by 50% compared to that in controls. We observed a similar expression pattern for miR-1. Taken together, the murine and human data indicate an inverse correlation between miR-133 and miR-1 expression and myocardial hypertrophy. 261 hsa-mir-133a-2 Long QT Syndrome 17965831 miR-133 was shown to inhibit the expression of ERG (ether-a-go-go-related gene) and cause depression of the potassium channel I(Kr). This inhibition contributed to long QT syndrome and arrhythmia in a diabetic rat model. 262 hsa-mir-133a-2 Musculoskeletal Abnormalities 17917533 Studies performed to determine whether skeletal muscle hypertrophy affects miRNA expression showed that miR-1 and miR-133 were decreased, suggesting that these muscle-specific miRNAs may contribute to regulating the initial response of skeletal muscle to functional overload. 263 hsa-mir-133b Parkinson Disease 17761882 Expression of one of these precursor miRNAs, miR-133b, was specifically enriched in the midbrain and deficient in the context of Parkinson's disease patient samples, as determined by ribonuclease (RNase) protection assays, qPCR, and Northern blotting for mature miR-133b. 264 hsa-mir-134 Fragile X Syndrome 17982590 spine morphology in patients with Fragile-X mental retardation syndrome (FXS) is not dissimilar from the spine structure observed on miR-134 overexpression or in neurons deficient for the miR-134 target Limk1 265 hsa-mir-135a-1 Heart Failure 17606841 downregulated 266 hsa-mir-135a-2 Heart Failure 17606841 downregulated 267 hsa-mir-136 Heart Failure 17606841 downregulated 268 hsa-mir-140 Lung Neoplasms 16530703 downregulation 269 hsa-mir-140 Muscular Disorders, Atrophic 17942673 dysregulation 270 hsa-mir-141 Cholangiocarcinoma 17355635 These include miR-200b and miR-141 which have been shown to be highly overexpressed in malignant cholangiocytes and in colon carcinoma. 271 hsa-mir-141 Colonic Neoplasms 17355635 These include miR-200b and miR-141 which have been shown to be highly overexpressed in malignant cholangiocytes and in colon carcinoma. 272 hsa-mir-141 Thyroid Neoplasms 17355635 Three of these upregulated miRNAs showed significantly higher fold change than the other upregulated miRNAs, these are mir-200a, mir-200b and mir-141. 273 hsa-mir-142 Leukemia, B-Cell 16885332 It was shown later that miR-142 is located at the chromosome 17 breakpoint and that c-Myc was rearranged under the control of the promoter of miR-142 with consequent overexpression. 274 hsa-mir-142 Leukemia, B-Cell 12007417 A translocation that make MYC overexpression 275 hsa-mir-143 Breast Neoplasms 17940623 Studies have implicated other miRNAs in tumorigenesis. MiR-143 and miR-145, for instance, have been shown to be constantly down-regulated in colorectal tumors, and recent studies by Croce et al. also have shown that the downregulation of these miRNAs is a common occurrence in breast carcinomas and breast cancer lines. 276 hsa-mir-143 Colonic Neoplasms 16195701 downregulation 277 hsa-mir-143 Colonic Neoplasms 16885332 miR-143 and miR-145 expression is reduced. 278 hsa-mir-143 Colonic Neoplasms 16940181 Downregulation of Mir-143 and Mir-145 has been observed in colorectal cancer. 279 hsa-mir-143 Colonic Neoplasms 14573789 reduced miRNA levels 280 hsa-mir-143 Colonic Neoplasms 17940623 Studies have implicated other miRNAs in tumorigenesis. MiR-143 and miR-145, for instance, have been shown to be constantly down-regulated in colorectal tumors, and recent studies by Croce et al. also have shown that the downregulation of these miRNAs is a common occurrence in breast carcinomas and breast cancer lines. 281 hsa-mir-143 Colorectal Neoplasms 16847880 reduced 282 hsa-mir-143 Hepatitis, Chronic 16331254 downregulated 283 hsa-mir-143 Hepatitis, Chronic 17188425 miRNA-143 and -145 levels increase as disease progresses from chronic hepatitis to cirrhosis, suggesting that they may turn on inflammatory or fibrosis related genes and/or turn off tumor suppressor genes. 284 hsa-mir-143 Lung Neoplasms 16530703 downregulation 285 hsa-mir-143 Muscular Disorders, Atrophic 17942673 dysregulation 286 hsa-mir-143 Obesity 16195701 Modified oligonucleotide complementary to miR-143 effectively suppressed adipocyte differentiation by modulation of its putative target ERK5, a protein previously known to be implicated in MAP kinase signaling pathways. 287 hsa-mir-144 Thyroid Neoplasms 17355635 three miRNAs showed significantly more underexpression compared to the other downregulated miRNAs. These miRNAs are as follows mir-127, mir-130a and mir-144. 288 hsa-mir-145 Breast Neoplasms 17940623 Studies have implicated other miRNAs in tumorigenesis. MiR-143 and miR-145, for instance, have been shown to be constantly down-regulated in colorectal tumors, and recent studies by Croce et al. also have shown that the downregulation of these miRNAs is a common occurrence in breast carcinomas and breast cancer lines. 289 hsa-mir-145 Breast Neoplasms 16103053 downregulation 290 hsa-mir-145 Breast Neoplasms 17028596 mir-145 downregulated in breast cancer (Iorio et al., 2005) and lung cancer and deleted in prostate cancer (Yanaihara et al., 2006); 291 hsa-mir-145 Breast Neoplasms 16885332 Reduced expression in breast cancers 292 hsa-mir-145 Breast Neoplasms 16466964 down-regulated 293 hsa-mir-145 Colonic Neoplasms 16195701 downregulation 294 hsa-mir-145 Colonic Neoplasms 16885332 Reduced accumulation in colon adenomas and carcinomas 295 hsa-mir-145 Colonic Neoplasms 14573789 reduced miRNA levels 296 hsa-mir-145 Colonic Neoplasms 16940181 Downregulation of Mir-143 and Mir-145 has beenobserved in colorectal cancer. 297 hsa-mir-145 Colonic Neoplasms 16885332 miR-143 and miR-145 expression is reduced. 298 hsa-mir-145 Colonic Neoplasms 17940623 Studies have implicated other miRNAs in tumorigenesis. MiR-143 and miR-145, for instance, have been shown to be constantly down-regulated in colorectal tumors, and recent studies by Croce et al. also have shown that the downregulation of these miRNAs is a common occurrence in breast carcinomas and breast cancer lines. 299 hsa-mir-145 Colorectal Neoplasms 16847880 reduced 300 hsa-mir-145 Hepatitis, Chronic 17188425 miRNA-143 and -145 levels increase as disease progresses from chronic hepatitis to cirrhosis, suggesting that they may turn on inflammatory or fibrosis related genes and/or turn off tumor suppressor genes. 301 hsa-mir-145 Lung Neoplasms 17028596 mir-145 downregulated in breast cancer (Iorio et al., 2005) and lung cancer and deleted in prostate cancer (Yanaihara et al., 2006); 302 hsa-mir-145 Lung Neoplasms 16530703 downregulation 303 hsa-mir-145 Muscular Disorders, Atrophic 17942673 dysregulation 304 hsa-mir-145 Prostatic Neoplasms 17028596 mir-145 downregulated in breast cancer (Iorio et al., 2005) and lung cancer and deleted in prostate cancer (Yanaihara et al., 2006); 305 hsa-mir-146a Breast Neoplasms 16461460 overexpressed 306 hsa-mir-146a Leukemia, Lymphocytic, Chronic, B-Cell 16251535 overexpression 307 hsa-mir-146a Lung Neoplasms 16530703 upregulation 308 hsa-mir-146a Muscular Disorders, Atrophic 17942673 dysregulation 309 hsa-mir-146a Pancreatic Neoplasms 16461460 overexpressed 310 hsa-mir-146a Prostatic Neoplasms 16461460 overexpressed 311 hsa-mir-146a Psoriasis 17965831 miR-146 is also expressed highly in the skin of psoriasis patients. 312 hsa-mir-146a Psoriasis 17622355 miR-146a was significantly over-expressed in psoriatic lesional skin p<0.001) but not in atopic eczema lesions when compared with healthy skin. 313 hsa-mir-146a Thyroid Neoplasms 17355635 Recent studies in miRNA deregulation PTC found an aberrant miRNA expression profile in PTCs compared to normal thyroid tissues. In particular, a significant increase in mir-222, mir-221, mir-146. 314 hsa-mir-146a Thyroid Neoplasms 17012848 Mir-221, mir-22 and mir-146 are significantly upregulated in this disease, whereas the expression of their predicted target gene KIT is lost, concurrently with the miRNA upregulation. 315 hsa-mir-146a Thyroid Neoplasms 17965831 Numerous miRNAs are also up-regulated in papillary thyroid carcinoma, including miR-221, miR-22 and miR-146. This up-regulation was associated with a downregulation in the expression of the oncogene KIT, a tyrosine kinase important for the control of cell proliferation. 316 hsa-mir-146a Thyroid Neoplasms 16885332 up-regulation 317 hsa-mir-146a Thyroid Neoplasms 17468766 somatic mutations altering binding sites for miR-221, miR-222 and miR-146 have been observed in the 3?? UTR of the KIT oncogene in papillary thyroid carcinoma. 318 hsa-mir-146b Breast Neoplasms 16461460 overexpressed 319 hsa-mir-146b Leukemia, Lymphocytic, Chronic, B-Cell 16251535 overexpression 320 hsa-mir-146b Lung Neoplasms 16530703 upregulation 321 hsa-mir-146b Muscular Disorders, Atrophic 17942673 Ten different miRNAs showing distinct expression patterns in the 10 different diseases (miR-21, miR-22, miR-29c, miR-30a-3p, miR-146b, miR-221, miR-368, miR-379, Ambi-miR-693, and Ambi-miR-11040). 322 hsa-mir-146b Muscular Disorders, Atrophic 17942673 dysregulation 323 hsa-mir-146b Pancreatic Neoplasms 16461460 overexpressed 324 hsa-mir-146b Prostatic Neoplasms 16461460 overexpressed 325 hsa-mir-146b Psoriasis 17965831 miR-146 is also expressed highly in the skin of psoriasis patients. 326 hsa-mir-146b Thyroid Neoplasms 17355635 Recent studies in miRNA deregulation PTC found an aberrant miRNA expression profile in PTCs compared to normal thyroid tissues. In particular, a significant increase in mir-222, mir-221, mir-146. 327 hsa-mir-146b Thyroid Neoplasms 17012848 Mir-221, mir-22 and mir-146 are significantly upregulated in this disease, whereas the expression of their predicted target gene KIT is lost, concurrently with the miRNA upregulation. 328 hsa-mir-146b Thyroid Neoplasms 17965831 Numerous miRNAs are also up-regulated in papillary thyroid carcinoma, including miR-221, miR-22 and miR-146. This up-regulation was associated with a downregulation in the expression of the oncogene KIT, a tyrosine kinase important for the control of cell proliferation. 329 hsa-mir-146b Thyroid Neoplasms 16885332 up-regulation 330 hsa-mir-146b Thyroid Neoplasms 17468766 somatic mutations altering binding sites for miR-221, miR-222 and miR-146 have been observed in the 3?? UTR of the KIT oncogene in papillary thyroid carcinoma. 331 hsa-mir-148a Asthma 17847008 Previously, we identified HLA-G as an asthma-susceptibility gene and discovered that the risk of asthma in a child was determined by both the child's HLA-G genotype and the mother's affection status. The activity of pluc-HLAG-G in the presence of each of the three miRNAs was significantly lower than those of pluc-HLAG-C and pluc-HLA-G-Del. 332 hsa-mir-148a Heart Failure 17606841 downregulated 333 hsa-mir-148a Muscular Disorders, Atrophic 17942673 dysregulation 334 hsa-mir-148b Asthma 17847008 Previously, we identified HLA-G as an asthma-susceptibility gene and discovered that the risk of asthma in a child was determined by both the child's HLA-G genotype and the mother's affection status. The activity of pluc-HLAG-G in the presence of each of the three miRNAs was significantly lower than those of pluc-HLAG-C and pluc-HLA-G-Del. 335 hsa-mir-150 Cardiomyopathy, Hypertrophic 17108080 downregulated 336 hsa-mir-150 Cardiomyopathy, Hypertrophic 17108080 miR-150 and miR-181b, which were down-regulated during hypertrophy, caused a reduction in cardiomyocyte cell size. 337 hsa-mir-150 Heart Failure 17606841 downregulated 338 hsa-mir-150 Lung Neoplasms 16530703 upregulation 339 hsa-mir-150 Polycythemia Vera 17976518 Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11. 340 hsa-mir-151a Muscular Disorders, Atrophic 17942673 dysregulation 341 hsa-mir-152 Asthma 17847008 Previously, we identified HLA-G as an asthma-susceptibility gene and discovered that the risk of asthma in a child was determined by both the child's HLA-G genotype and the mother's affection status. The activity of pluc-HLAG-G in the presence of each of the three miRNAs was significantly lower than those of pluc-HLAG-C and pluc-HLA-G-Del. 342 hsa-mir-154 Muscular Disorders, Atrophic 17942673 dysregulation 343 hsa-mir-155 Breast Neoplasms 16461460 overexpressed 344 hsa-mir-155 Breast Neoplasms 16466964 overexpressed 345 hsa-mir-155 Breast Neoplasms 16103053 upregulated 346 hsa-mir-155 Breast Neoplasms 16885332 Overexpression in breast cancers 347 hsa-mir-155 Burkitt Lymphoma 17965831 miR-155 has also been implicated in a number of cancers including Burkitt_s lymphoma, Hodgkin lymphoma and lung cancer. 348 hsa-mir-155 Burkitt Lymphoma 16195701 overexpression 349 hsa-mir-155 Burkitt Lymphoma 14695998 upregulated 350 hsa-mir-155 Burkitt Lymphoma 16940181 Increased expression of the precursor of Mir-155has been detected in pediatric Burkitt lymphoma. 351 hsa-mir-155 Burkitt Lymphoma 16466964 overexpressed 352 hsa-mir-155 Colonic Neoplasms 16461460 overexpressed 353 hsa-mir-155 Down Syndrome 17468766 Because miR-155 maps to chromosome 21, Setupathy et al. speculate that miR-155 overexpression in trisomics ?a which they confirmed experimentally ?a accounts for the lower levels of diastolic and systolic blood pressure associated with Down syndrome. 354 hsa-mir-155 Hodgkin Disease 17965831 miR-155 has also been implicated in a number of cancers including Burkitt_s lymphoma, Hodgkin lymphoma and lung cancer. 355 hsa-mir-155 Hodgkin Disease 16466964 overexpressed 356 hsa-mir-155 Hodgkin Disease 12661002 upregulated 357 hsa-mir-155 Leukemia, B-Cell 16736018 upregulation of miR-155 and the miR-17-92 cluster 358 hsa-mir-155 Leukemia, B-Cell 16466964 overexpressed 359 hsa-mir-155 Leukemia, B-Cell 17940623 miR-155 is encoded by nucleotides 241-262 of BIC, which was originally identified as a transcript derived from an integration site for the avian leucosis virus and found to be overexpressed in B-cell lymphomas. The role of miR-155 is not restricted to B cell lymphomas, however. Recent studies have reported that miR-155 is upregulated in breast, lung, colon, and thyroid cancers. 360 hsa-mir-155 Leukemia, Lymphocytic, Chronic, B-Cell 16251535 overexpression 361 hsa-mir-155 Lung Neoplasms 17028302 A high expression of miR-155 has been suggested to be significantly associated with unfavorable prognosis in lung adenocarcinoma patients. 362 hsa-mir-155 Lung Neoplasms 17965831 miR-155 has also been implicated in a number of cancers including Burkitt_s lymphoma, Hodgkin lymphoma and lung cancer. 363 hsa-mir-155 Lung Neoplasms 16461460 overexpressed 364 hsa-mir-155 Lung Neoplasms 16530703 upregulation 365 hsa-mir-155 Lung Neoplasms 17028596 High mir-155 associated with poor prognosis in lung cancer (Yanaihara et al., 2006). 366 hsa-mir-155 Lymphoma, B-Cell 15738415 upregulated 367 hsa-mir-155 Lymphoma, Large B-Cell, Diffuse 16041695 upregulated 368 hsa-mir-155 Lymphoma, Large B-Cell, Diffuse 17487835 DLBCL cases over-expressed miR-21, miR-155 and miR-221 by an average of 9.3, 4.6 and 2.3-fold respectively compared to normal peripheral blood B cells. 369 hsa-mir-155 Muscular Disorders, Atrophic 17942673 dysregulation 370 hsa-mir-155 Neoplasms 16885332 High expression of precursor miR-155/BIC in pediatric BL, but lack of BIC and miR-155 expression in adult BL 371 hsa-mir-155 Polycythemia Vera 17976518 Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11. 372 hsa-mir-155 Renal Insufficiency 17965831 miR-155 was shown to decrease the expression of angiotensin II type 1 receptor in human primary fibroblasts [175]. This suggests that miR-155 may regulate a diverse set of physiological functions including fluid homeostasis and renal function. 373 hsa-mir-15a Breast Neoplasms 17012848 Later on, deletion of mir-16-1 and mir-15a deletion were also identified in epithelial tumors, such as pituitary adenomas, ovarian and breast cancer. 374 hsa-mir-15a Leukemia 16166262 the deletion or downregulation of mir-15a results in increased expression of BCL2. 375 hsa-mir-15a Leukemia 12434020 deletion or downregulation 376 hsa-mir-15a Leukemia, B-Cell 16885332 Deleted and down-regulated in the majority of B-CLLs 377 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 17965831 miR-15a and miR-16 are often deleted from chromosome 13q14.2 in patients with B cell CLL, suggesting that these miRNAs may be involved in tumour suppression. Additionally, introduction of exogenous miR-16 into a malignant B-1 cell line resulted in increased apoptosis. 378 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 17940623 The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells. 379 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 17012848 It was found that mir-16-1 and mir-15a at 13q14 are deleted in more than 50% patients, with concurrent reduced expression in ~65% patients. Further studies demonstrated that these two miRNAs suppress BCL2 expression and may serve as tumor suppressor genes in this disease. 380 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 17234972 After years of futile attemptsto identify the gene(s) in the deleted 13q14 region that participatein the pathogenesis of chronic lymphocytic leukemia, Calin etal discovered that miR-15 and miR-16 are located within thissequence and that both are downregulated in 68% of cases. 381 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 16251535 overexpression 382 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 17531469 The loss-of-function of miR-15a and miR-16-1 in CLL, and perhaps other cancers as well, may contribute to malignant transformation by upregulating Bcl2 thereby preventing apoptosis. 383 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 12434020 deletion or downregulation 384 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 16885332 The finding that essentially all indolent CLLs have lost miR-15a/miR-16-1 expression suggests that this event is the initiating event in the pathogenesis of the indolent form of CLL. 385 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 17028302 Detailed analyses of deletion and expression status revealed these two miRNAs to be located within a 30 kb minimally deleted region in chronic lymphocytic leukemia (CLL) patients, both of which were deleted or downregulated in most CLL cases, suggesting that miR-15a and miR-16-1 may function as tumor suppressor genes. 386 hsa-mir-15a Lymphoma 16166262 the deletion or downregulation of mir-15a results in increased expression of BCL2. 387 hsa-mir-15a Lymphoma, Mantle-Cell 17940623 The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells. 388 hsa-mir-15a Multiple Myeloma 17940623 The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells. 389 hsa-mir-15a Pituitary Neoplasms 17028302 Downregulation of miR-15 and miR-16 miRNAs also appears to be a feature of pituitary adenomas. 390 hsa-mir-15a Pituitary Neoplasms 16885332 a type of benign tumors displaying deletions at 13q14.3 and reduced expression of miR-16-1 and miR-15a 391 hsa-mir-15a Pituitary Neoplasms 16885332 Down-regulation in pituitary adenomas 392 hsa-mir-15a Prostatic Neoplasms 17940623 The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells. 393 hsa-mir-15b Hepatitis, Chronic 16331254 overexpression 394 hsa-mir-15b Leukemia, Lymphocytic, Chronic, B-Cell 17234972 After years of futile attemptsto identify the gene(s) in the deleted 13q14 region that participatein the pathogenesis of chronic lymphocytic leukemia, Calin etal discovered that miR-15 and miR-16 are located within thissequence and that both are downregulated in 68% of cases. 395 hsa-mir-15b Pituitary Neoplasms 17028302 Downregulation of miR-15 and miR-16 miRNAs also appears to be a feature of pituitary adenomas. 396 hsa-mir-16-1 Autoimmune Diseases 17351108 New Zealand black (NZB) mice (NZB) tissue sourcesof RNA showed a decrease in miR-16 in the spleen; however, theNZB kidney was not decreased in miR-16 expression compared withthe control strain expression. In addition, the NZB-derivedmalignant B-cell line, LNC, had an even greater decreased expressionof miR-16 compared with C57Bl6 spleen. 397 hsa-mir-16-1 Heart Failure 17606841 downregulated 398 hsa-mir-16-1 Leukemia 16166262 the deletion or downregulation of mir-15a results in increased expression of BCL2. 399 hsa-mir-16-1 Leukemia 12434020 deletion or downregulation 400 hsa-mir-16-1 Leukemia, B-Cell 16885332 Deleted and down-regulated in the majority of B-CLLs 401 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 16251535 mutation 402 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 17012848 It was found that mir-16-1 and mir-15a at 13q14 are deleted in more than 50% patients, with concurrent reduced expression in ~65% patients. Further studies demonstrated that these two miRNAs suppress BCL2 expression and may serve as tumor suppressor genes in this disease. 403 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 17351108 New Zealand black (NZB) mice (NZB) tissue sourcesof RNA showed a decrease in miR-16 in the spleen; however, theNZB kidney was not decreased in miR-16 expression compared withthe control strain expression. In addition, the NZB-derivedmalignant B-cell line, LNC, had an even greater decreased expressionof miR-16 compared with C57Bl6 spleen. 404 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 17940623 The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells. 405 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 17234972 After years of futile attemptsto identify the gene(s) in the deleted 13q14 region that participatein the pathogenesis of chronic lymphocytic leukemia, Calin etal discovered that miR-15 and miR-16 are located within thissequence and that both are downregulated in 68% of cases. 406 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 17531469 he loss-of-function of miR-15a and miR-16-1 in CLL, and perhaps other cancers as well, may contribute to malignant transformation by upregulating Bcl2 thereby preventing apoptosis. 407 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 17965831 miR-15a and miR-16 are often deleted from chromosome 13q14.2 in patients with B cell CLL, suggesting that these miRNAs may be involved in tumour suppression. Additionally, introduction of exogenous miR-16 into a malignant B-1 cell line resulted in increased apoptosis. 408 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 17028302 Detailed analyses of deletion and expression status revealed these two miRNAs to be located within a 30 kb minimally deleted region in chronic lymphocytic leukemia (CLL) patients, both of which were deleted or downregulated in most CLL cases, suggesting that miR-15a and miR-16-1 may function as tumor suppressor genes. 409 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 16885332 The finding that essentially all indolent CLLs have lost miR-15a/miR-16-1 expression suggests that this event is the initiating event in the pathogenesis of the indolent form of CLL. 410 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 12434020 deletion or downregulation 411 hsa-mir-16-1 Lymphoma 16166262 the deletion or downregulation of mir-15a results in increased expression of BCL2. 412 hsa-mir-16-1 Lymphoma, Mantle-Cell 17940623 The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells. 413 hsa-mir-16-1 Lymphoproliferative Disorders 17351108 New Zealand black (NZB) mice (NZB) tissue sourcesof RNA showed a decrease in miR-16 in the spleen; however, theNZB kidney was not decreased in miR-16 expression compared withthe control strain expression. In addition, the NZB-derivedmalignant B-cell line, LNC, had an even greater decreased expressionof miR-16 compared with C57Bl6 spleen. 414 hsa-mir-16-1 Multiple Myeloma 17940623 The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells. 415 hsa-mir-16-1 Ovarian Neoplasms 17012848 Later on, deletion of mir-16-1 and mir-15a deletion were also identified in epithelial tumors, such as pituitary adenomas, ovarian and breast cancer. 416 hsa-mir-16-1 Pituitary Neoplasms 16885332 a type of benign tumors displaying deletions at 13q14.3 and reduced expression of miR-16-1 and miR-15a 417 hsa-mir-16-1 Pituitary Neoplasms 17028302 Downregulation of miR-15 and miR-16 miRNAs also appears to be a feature of pituitary adenomas. 418 hsa-mir-16-1 Pituitary Neoplasms 16885332 Down-regulation in pituitary adenomas 419 hsa-mir-16-1 Pituitary Neoplasms 17012848 Later on, deletion of mir-16-1 and mir-15a deletion were also identified in epithelial tumors, such as pituitary adenomas, ovarian and breast cancer. 420 hsa-mir-16-1 Polycythemia Vera 17976518 Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11. 421 hsa-mir-16-1 Prostatic Neoplasms 17940623 The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells. 422 hsa-mir-16-2 Autoimmune Diseases 17351108 New Zealand black (NZB) mice (NZB) tissue sourcesof RNA showed a decrease in miR-16 in the spleen; however, theNZB kidney was not decreased in miR-16 expression compared withthe control strain expression. In addition, the NZB-derivedmalignant B-cell line, LNC, had an even greater decreased expressionof miR-16 compared with C57Bl6 spleen. 423 hsa-mir-16-2 Heart Failure 17606841 downregulated 424 hsa-mir-16-2 Leukemia, Lymphocytic, Chronic, B-Cell 17351108 New Zealand black (NZB) mice (NZB) tissue sourcesof RNA showed a decrease in miR-16 in the spleen; however, theNZB kidney was not decreased in miR-16 expression compared withthe control strain expression. In addition, the NZB-derivedmalignant B-cell line, LNC, had an even greater decreased expressionof miR-16 compared with C57Bl6 spleen. 425 hsa-mir-16-2 Leukemia, Lymphocytic, Chronic, B-Cell 17234972 After years of futile attemptsto identify the gene(s) in the deleted 13q14 region that participatein the pathogenesis of chronic lymphocytic leukemia, Calin etal discovered that miR-15 and miR-16 are located within thissequence and that both are downregulated in 68% of cases. 426 hsa-mir-16-2 Leukemia, Lymphocytic, Chronic, B-Cell 17965831 miR-15a and miR-16 are often deleted from chromosome 13q14.2 in patients with B cell CLL, suggesting that these miRNAs may be involved in tumour suppression. Additionally, introduction of exogenous miR-16 into a malignant B-1 cell line resulted in increased apoptosis. 427 hsa-mir-16-2 Lymphoproliferative Disorders 17351108 New Zealand black (NZB) mice (NZB) tissue sourcesof RNA showed a decrease in miR-16 in the spleen; however, theNZB kidney was not decreased in miR-16 expression compared withthe control strain expression. In addition, the NZB-derivedmalignant B-cell line, LNC, had an even greater decreased expressionof miR-16 compared with C57Bl6 spleen. 428 hsa-mir-16-2 Pituitary Neoplasms 17028302 Downregulation of miR-15 and miR-16 miRNAs also appears to be a feature of pituitary adenomas. 429 hsa-mir-16-2 Polycythemia Vera 17976518 Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11. 430 hsa-mir-17 Breast Neoplasms 16461460 overexpressed 431 hsa-mir-17 Breast Neoplasms 17442096 In breast cancer cells, mir-17-5p expression is decreased. 432 hsa-mir-17 Breast Neoplasms 16940181 We report here on the role of Mir-17-5p, a potentialtranslational repressor of the AIB1 (named for "amplified in breast cancer 1") oncogene, in the controlof breast cancer cell proliferation. Downregulationof Mir-17-5p may be important for breast cancer cell growth. 433 hsa-mir-17 Breast Neoplasms 17965831 miR-17-5p was down-regulated in breast cancer cells, and enhanced expression decreased tumour cell proliferation. 434 hsa-mir-17 Breast Neoplasms 16940181 The genomic location of Mir-17-5p also undergoesloss of heterozygosity in different types of cancer, including breast cancer. 435 hsa-mir-17 Carcinoma, Hepatocellular 15944709 loss of heterozygosity of this cluster 436 hsa-mir-17 Colonic Neoplasms 17965831 The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation. 437 hsa-mir-17 Colonic Neoplasms 16461460 overexpressed 438 hsa-mir-17 Heart Failure 17606841 downregulated 439 hsa-mir-17 Heart Failure 17606841 upregulated 440 hsa-mir-17 Hematologic Neoplasms 17011485 The miR-17-92 cluster is amplified in hematopoietic malignancies. 441 hsa-mir-17 Leukemia, B-Cell 16224045 Overexpression 442 hsa-mir-17 Leukemia, B-Cell 15944707 overexpression 443 hsa-mir-17 Leukemia, B-Cell 17940623 These data suggested a direct involvement of this miRNA cluster in tumorigenesis. The miR-17-92 cluster encompassing six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1. 444 hsa-mir-17 Leukemia, B-Cell 16736018 upregulation of miR-155 and the miR-17-92 cluster 445 hsa-mir-17 Leukemia, B-Cell 17989227 the miR-17 cluster (8, 9) synergizes with MYC to induce B cell lymphoma. 446 hsa-mir-17 Lung Neoplasms 17965831 The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation. 447 hsa-mir-17 Lung Neoplasms 17965831 inhibition of miR-17-5 (and miR-20a) using antisense oligonucleotides enhanced apoptosis in lung cancer cells, further supporting an important role for the miRNAcluster miR-17-92 in tumour progression [85]. 448 hsa-mir-17 Lung Neoplasms 16266980 overexpressed 449 hsa-mir-17 Lung Neoplasms 16530703 upregulation 450 hsa-mir-17 Lung Neoplasms 16461460 overexpressed 451 hsa-mir-17 Lung Neoplasms 17442096 The mir-17 cluster is also overexpressed in human lung cancer. 452 hsa-mir-17 Lung Neoplasms 16885332 Overexpressed in lung cancers 453 hsa-mir-17 Lymphoma 16940181 Mir-17-5p, also known as Mir-91,is located on chromosome 13q31; this gene is amplified in childhoodlymphoma. 454 hsa-mir-17 Lymphoma 16885332 Primary transcripts overexpressed in lymphomas 455 hsa-mir-17 Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. 456 hsa-mir-17 Lymphoma, B-Cell 15944707 overexpressed 457 hsa-mir-17 Neoplasms 17189674 Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer. 458 hsa-mir-17 Neoplasms 17060945 overexpressed 459 hsa-mir-17 Pancreatic Neoplasms 16461460 overexpressed 460 hsa-mir-17 Prostatic Neoplasms 16461460 overexpressed 461 hsa-mir-181a-1 Heart Failure 17606841 upregulated 462 hsa-mir-181a-1 Leukemia, Lymphocytic, Chronic, B-Cell 17604727 absent 463 hsa-mir-181a-1 Leukemia, Promyelocytic, Acute 16847880 miR-181 expression is decreased inTPA-induced differentiation of human promyelocytic leukemia cells. 464 hsa-mir-181a-1 Thyroid Neoplasms 17355635 Another miRNA these two groups found to be upregulated albeit less significantly was miR-213, our study also found miR-213 to be upregulated in BRAF mutated cell lines [25 fold]. 465 hsa-mir-181a-2 Leukemia, Promyelocytic, Acute 16847880 miR-181 expression is decreased inTPA-induced differentiation of human promyelocytic leukemia cells. 466 hsa-mir-181b-1 Breast Neoplasms 16461460 overexpressed 467 hsa-mir-181b-1 Cardiomyopathy, Hypertrophic 17108080 downregulated 468 hsa-mir-181b-1 Cardiomyopathy, Hypertrophic 17108080 miR-150 and miR-181b, which were down-regulated during hypertrophy, caused a reduction in cardiomyocyte cell size. 469 hsa-mir-181b-1 Leukemia, Promyelocytic, Acute 16847880 miR-181 expression is decreased inTPA-induced differentiation of human promyelocytic leukemia cells. 470 hsa-mir-181b-1 Pancreatic Neoplasms 16461460 overexpressed 471 hsa-mir-181b-1 Prostatic Neoplasms 16461460 overexpressed 472 hsa-mir-181b-2 Cardiomyopathy, Hypertrophic 17108080 downregulated 473 hsa-mir-181b-2 Cardiomyopathy, Hypertrophic 17108080 miR-150 and miR-181b, which were down-regulated during hypertrophy, caused a reduction in cardiomyocyte cell size. 474 hsa-mir-181b-2 Leukemia, Promyelocytic, Acute 16847880 miR-181 expression is decreased inTPA-induced differentiation of human promyelocytic leukemia cells. 475 hsa-mir-181b-2 Urinary Bladder Neoplasms 17470785 mir-181b-2 and mir-199b are 3.3 Mb from the peak of the colon Scc2 locus on Chr 2; homologous human miRNAs are located inside a cancer-associated genomic region, which is a region commonly deleted in bladder cancer. 476 hsa-mir-181c Lung Neoplasms 16530703 downregulation 477 hsa-mir-181c Lung Neoplasms 17028596 mir-181c-prec downregulated in lung cancer (Yanaihara et al., 2006); 478 hsa-mir-181d Leukemia, Promyelocytic, Acute 16847880 miR-181 expression is decreased inTPA-induced differentiation of human promyelocytic leukemia cells. 479 hsa-mir-182 Heart Failure 17606841 downregulated 480 hsa-mir-182 Hepatitis, Chronic 16331254 overexpression 481 hsa-mir-183 Lung Neoplasms 17028596 mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006); 482 hsa-mir-186 Heart Failure 17606841 downregulated 483 hsa-mir-187 Leukemia, Lymphocytic, Chronic, B-Cell 16251535 mutation 484 hsa-mir-18a Carcinoma, Hepatocellular 16331254 upregulated 485 hsa-mir-18a Carcinoma, Hepatocellular 15944709 loss of heterozygosity of this cluster 486 hsa-mir-18a Colonic Neoplasms 17965831 The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation. 487 hsa-mir-18a Hematologic Neoplasms 17011485 The miR-17-92 cluster is amplified in hematopoietic malignancies. 488 hsa-mir-18a Leukemia, B-Cell 16224045 Overexpression 489 hsa-mir-18a Leukemia, B-Cell 15944707 overexpression 490 hsa-mir-18a Leukemia, B-Cell 17940623 These data suggested a direct involvement of this miRNA cluster in tumorigenesis. The miR-17-92 cluster encompassing six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1. 491 hsa-mir-18a Leukemia, B-Cell 16736018 upregulation of miR-155 and the miR-17-92 cluster 492 hsa-mir-18a Lung Neoplasms 16885332 Overexpressed in lung cancers 493 hsa-mir-18a Lung Neoplasms 17965831 The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation. 494 hsa-mir-18a Lung Neoplasms 16266980 overexpressed 495 hsa-mir-18a Lymphoma 16885332 Primary transcripts overexpressed in lymphomas 496 hsa-mir-18a Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. 497 hsa-mir-18a Lymphoma, B-Cell 15944707 overexpressed 498 hsa-mir-18a Neoplasms 17189674 Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17¨C19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer. 499 hsa-mir-18b Carcinoma, Hepatocellular 16331254 upregulated 500 hsa-mir-18b Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. 501 hsa-mir-18b Neoplasms 17189674 Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17¨C19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer. 502 hsa-mir-191 Colonic Neoplasms 16461460 overexpressed 503 hsa-mir-191 Lung Neoplasms 16461460 overexpressed 504 hsa-mir-191 Lung Neoplasms 16530703 upregulation 505 hsa-mir-191 Neoplasms 17060945 overexpressed 506 hsa-mir-191 Pancreatic Neoplasms 16461460 overexpressed 507 hsa-mir-191 Prostatic Neoplasms 16461460 overexpressed 508 hsa-mir-191 Stomach Neoplasms 16461460 overexpressed 509 hsa-mir-192 Heart Failure 17606841 downregulated 510 hsa-mir-192 Lung Neoplasms 16530703 mir-192-prec downregulation 511 hsa-mir-192 Lung Neoplasms 16530703 upregulation 512 hsa-mir-194-1 Uterine Cervical Neoplasms 17470785 The list of miRNAs at or near sites commonly altered in human cancers includes mir-215 and mir-194-1, which are <0.17 kb from D1Mit208, a marker that defines the peak of the colon Scc3 locus on Chr 1. Homologous human miRNAs are located inside the FRA1H at Chr 1q42.1; this fragile site is an HPV16 integration site involved in cervical cancer. 513 hsa-mir-195 Carcinoma, Hepatocellular 17188425 miRNA-195 expression is decreased in HCC compared to nontumor liver [59], and is also deleted in lung cancer [65], suggesting it is tumor related. miRNA-195 alters the expression of methyl-CpG binding protein 2 (which alters DNA methylation), the SKI oncogene, and a Bcl-2 like protein [59], suggesting miRNA-195 may act as a tumor suppressor in HCC. 514 hsa-mir-195 Carcinoma, Hepatocellular 16331254 downregulated 515 hsa-mir-195 Cardiomyopathy, Hypertrophic 17786230 Cardiac-specific overexpression of miRNA-195 (miR-195), which is consistently upregulated in rodent and human hypertrophic hearts, for example, results in dilated cardiomyopathy and heart failure in mice as early as two weeks of age, implying that upregulation of miR-195 during cardiac hypertrophy actively contributes to the disease process. 516 hsa-mir-195 Cardiomyopathy, Hypertrophic 17108080 miR-23a, miR-23b, miR-24, miR-195, and miR-214, all of which were up-regulated during cardiac hypertrophy, appeared to be capable of inducing hypertrophic growth in vitro. 517 hsa-mir-195 Cardiomyopathy, Hypertrophic 17108080 overexpressed 518 hsa-mir-195 Cardiomyopathy, Hypertrophic 17108080 Cardiac overexpression of miR-195, which was up-regulated during cardiac hypertrophy, resulted in pathological cardiac growth and heart failure in transgenic mice. 519 hsa-mir-195 Heart Failure 17108080 overexpressed 520 hsa-mir-195 Leukemia, Lymphocytic, Chronic, B-Cell 16251535 overexpression 521 hsa-mir-195 Muscular Disorders, Atrophic 17942673 dysregulation 522 hsa-mir-195 Schizophrenia 17326821 downregulation 523 hsa-mir-196a-1 Heart Failure 17606841 upregulated 524 hsa-mir-196a-2 Heart Failure 17606841 upregulated 525 hsa-mir-197 Lung Neoplasms 16530703 upregulaion 526 hsa-mir-198 Lung Neoplasms 16530703 downregulation 527 hsa-mir-198 Schizophrenia 17849003 SNP (rs1700) disease susceptibility 528 hsa-mir-199a-1 Carcinoma, Hepatocellular 16331254 downregulated 529 hsa-mir-199a-1 Carcinoma, Hepatocellular 17188425 This region encodes miRNA-199a-1 (19p13.2), whose expression levels are lower in HCC compared to nontumor liver [59] and is deleted in several other tumor types. 530 hsa-mir-199a-1 Cardiomyopathy, Hypertrophic 17108080 overexpressed 531 hsa-mir-199a-1 Hepatitis, Chronic 16331254 downregulated 532 hsa-mir-199a-1 Lung Neoplasms 16461460 overexpressed 533 hsa-mir-199a-1 Muscular Disorders, Atrophic 17942673 dysregulation 534 hsa-mir-199a-1 Pancreatic Neoplasms 16461460 overexpressed 535 hsa-mir-199a-1 Prostatic Neoplasms 16461460 overexpressed 536 hsa-mir-199a-2 Carcinoma, Hepatocellular 16331254 downregulated 537 hsa-mir-199a-2 Cardiomyopathy, Hypertrophic 17108080 overexpressed 538 hsa-mir-199a-2 Hepatitis, Chronic 16331254 downregulated 539 hsa-mir-199a-2 Muscular Disorders, Atrophic 17942673 dysregulation 540 hsa-mir-199b Heart Failure 17606841 upregulated 541 hsa-mir-199b Hepatitis, Chronic 16331254 overexpression 542 hsa-mir-199b Lung Neoplasms 16530703 downregulation 543 hsa-mir-199b Muscular Disorders, Atrophic 17942673 dysregulation 544 hsa-mir-199b Urinary Bladder Neoplasms 17470785 mir-181b-2 and mir-199b are 3.3 Mb from the peak of the colon Scc2 locus on Chr 2; homologous human miRNAs are located inside a cancer-associated genomic region, which is a region commonly deleted in bladder cancer. 545 hsa-mir-19a Carcinoma, Hepatocellular 17188425 miRNA-19a/b activates PI3K by blocking expression of the tumor suppressor PTEN. 546 hsa-mir-19a Carcinoma, Hepatocellular 15944709 loss of heterozygosity of this cluster 547 hsa-mir-19a Colonic Neoplasms 17965831 The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation. 548 hsa-mir-19a Hematologic Neoplasms 17011485 The miR-17-92 cluster is amplified in hematopoietic malignancies. 549 hsa-mir-19a Leukemia, B-Cell 16224045 Overexpression 550 hsa-mir-19a Leukemia, B-Cell 15944707 overexpression 551 hsa-mir-19a Leukemia, B-Cell 17940623 These data suggested a direct involvement of this miRNA cluster in tumorigenesis. The miR-17-92 cluster encompassing six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1. 552 hsa-mir-19a Leukemia, B-Cell 16736018 upregulation of miR-155 and the miR-17-92 cluster 553 hsa-mir-19a Lung Neoplasms 17965831 The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation. 554 hsa-mir-19a Lung Neoplasms 16885332 Overexpressed in lung cancers 555 hsa-mir-19a Lung Neoplasms 16266980 overexpressed 556 hsa-mir-19a Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. 557 hsa-mir-19a Lymphoma 16885332 Primary transcripts overexpressed in lymphomas 558 hsa-mir-19a Lymphoma, B-Cell 15944707 overexpressed 559 hsa-mir-19a Neoplasms 17189674 Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17¨C19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer. 560 hsa-mir-19b-1 Carcinoma, Hepatocellular 17188425 miRNA-19a/b activates PI3K by blocking expression of the tumor suppressor PTEN. 561 hsa-mir-19b-1 Carcinoma, Hepatocellular 15944709 loss of heterozygosity of this cluster 562 hsa-mir-19b-1 Colonic Neoplasms 17965831 The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation. 563 hsa-mir-19b-1 Heart Failure 17606841 downregulated 564 hsa-mir-19b-1 Hematologic Neoplasms 17011485 The miR-17-92 cluster is amplified in hematopoietic malignancies. 565 hsa-mir-19b-1 Leukemia, B-Cell 16224045 Overexpression 566 hsa-mir-19b-1 Leukemia, B-Cell 15944707 overexpression 567 hsa-mir-19b-1 Leukemia, B-Cell 17940623 These data suggested a direct involvement of this miRNA cluster in tumorigenesis. The miR-17-92 cluster encompassing six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1. 568 hsa-mir-19b-1 Leukemia, B-Cell 16736018 upregulation of miR-155 and the miR-17-92 cluster 569 hsa-mir-19b-1 Lung Neoplasms 17965831 The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation. 570 hsa-mir-19b-1 Lung Neoplasms 16885332 Overexpressed in lung cancers 571 hsa-mir-19b-1 Lung Neoplasms 16266980 overexpressed 572 hsa-mir-19b-1 Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. 573 hsa-mir-19b-1 Lymphoma 16885332 Primary transcripts overexpressed in lymphomas 574 hsa-mir-19b-1 Lymphoma, B-Cell 15944707 overexpressed 575 hsa-mir-19b-1 Muscular Disorders, Atrophic 17942673 dysregulation 576 hsa-mir-19b-1 Neoplasms 17189674 Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17¨C19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer. 577 hsa-mir-19b-2 Carcinoma, Hepatocellular 17188425 miRNA-19a/b activates PI3K by blocking expression of the tumor suppressor PTEN. 578 hsa-mir-19b-2 Heart Failure 17606841 downregulated 579 hsa-mir-19b-2 Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. 580 hsa-mir-19b-2 Lymphoma, B-Cell 15944707 overexpressed 581 hsa-mir-19b-2 Muscular Disorders, Atrophic 17942673 dysregulation 582 hsa-mir-19b-2 Neoplasms 17189674 Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17¨C19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer. 583 hsa-mir-200a Carcinoma, Hepatocellular 16331254 downregulated 584 hsa-mir-200a Carcinoma, Hepatocellular 17188425 Integration at FRA1A may silence expression of miRNA-200a, which is known to be decreased in HCC compared to nontumor [59] and [65]. Since most miRNAs suppress their target proteins, and miRNA-200a is known to regulate the expression of RAB30, a member of the ras oncogene family [59], decreased miRNA-200a may promote elevated RAB30 expression in HCC. 585 hsa-mir-200a Thyroid Neoplasms 17355635 Three of these upregulated miRNAs showed significantly higher fold change than the other upregulated miRNAs, these are mir-200a, mir-200b and mir-141. 586 hsa-mir-200b Cholangiocarcinoma 17355635 These include miR-200b and miR-141 which have been shown to be highly overexpressed in malignant cholangiocytes and in colon carcinoma. 587 hsa-mir-200b Colonic Neoplasms 17355635 These include miR-200b and miR-141 which have been shown to be highly overexpressed in malignant cholangiocytes and in colon carcinoma. 588 hsa-mir-200b Thyroid Neoplasms 17355635 Three of these upregulated miRNAs showed significantly higher fold change than the other upregulated miRNAs, these are mir-200a, mir-200b and mir-141. 589 hsa-mir-200c Heart Failure 17606841 upregulated 590 hsa-mir-203 Lung Neoplasms 16530703 upregulation 591 hsa-mir-203 Psoriasis 17622355 upregulation (lead to downregulation of its target SOCS3) 592 hsa-mir-203 Psoriasis 17622355 In accordance with the microarray data, quantitative real-time PCR results showed significantly (p<0.001) increased miR-203 levels in psoriasis skin when compared with healthy skin. Moreover, miR-203 was expressed at a significantly (p<0.01) higher level in psoriasis than in atopic eczema skin specimen. 593 hsa-mir-204 Heart Failure 17606841 upregulated 594 hsa-mir-205 Heart Failure 17606841 upregulated 595 hsa-mir-205 Lung Neoplasms 16530703 upregulation 596 hsa-mir-206 Breast Neoplasms 17028596 mir-206 upregulated in breast cancer (Iorio et al., 2005). 597 hsa-mir-206 Leukemia, Lymphocytic, Chronic, B-Cell 16251535 mutation 598 hsa-mir-206 Musculoskeletal Abnormalities 17917533 Studies to evaluate the role of miRNAs in muscular dystrophy showed a dramatic increase in miR-206 expression in the diaphragm of the mdx mouse. 599 hsa-mir-206 Schizophrenia 17849003 SNP (rs17578796) disease susceptibility 600 hsa-mir-208a Cardiomyopathy, Hypertrophic 17965831 miR-208 was recently shown to enhance stress-related cardiac muscle growth by up-regulating a contractile protein, bMHC, possibly by repressing translation of thyroid hormone receptor-associated protein 1 (THRAP1). 601 hsa-mir-208a Endomyocardial Fibrosis 17786230 Clearly, miR-208 is also essential for expression of the genes involved in cardiac fibrosis and hypertrophic growth. 602 hsa-mir-208a Heart Failure 17606841 upregulated 603 hsa-mir-208a Heart Failure 17379774 upregulation 604 hsa-mir-208a Hypertrophy 17786230 Clearly, miR-208 is also essential for expression of the genes involved in cardiac fibrosis and hypertrophic growth. 605 hsa-mir-20a Breast Neoplasms 17011485 TGF-b-2 receptor is expressed in the epithelium of breast cancer and can be regulated by miR-20a, which is down- regulated in breast cancer. 606 hsa-mir-20a Carcinoma, Hepatocellular 16331254 overexpression 607 hsa-mir-20a Carcinoma, Hepatocellular 15944709 loss of heterozygosity of this cluster 608 hsa-mir-20a Colonic Neoplasms 17965831 The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation. 609 hsa-mir-20a Colonic Neoplasms 16461460 overexpressed 610 hsa-mir-20a Hematologic Neoplasms 17011485 The miR-17-92 cluster is amplified in hematopoietic malignancies. 611 hsa-mir-20a Leukemia, B-Cell 16224045 Overexpression 612 hsa-mir-20a Leukemia, B-Cell 15944707 overexpression 613 hsa-mir-20a Leukemia, B-Cell 17940623 These data suggested a direct involvement of this miRNA cluster in tumorigenesis. The miR-17-92 cluster encompassing six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1. 614 hsa-mir-20a Leukemia, B-Cell 16736018 upregulation of miR-155 and the miR-17-92 cluster 615 hsa-mir-20a Lung Neoplasms 17965831 The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation. 616 hsa-mir-20a Lung Neoplasms 16885332 Overexpressed in lung cancers 617 hsa-mir-20a Lung Neoplasms 16266980 overexpressed 618 hsa-mir-20a Lymphoma 16885332 Primary transcripts overexpressed in lymphomas 619 hsa-mir-20a Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. 620 hsa-mir-20a Neoplasms 17189674 Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17¨C19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer. 621 hsa-mir-20a Pancreatic Neoplasms 16461460 overexpressed 622 hsa-mir-20a Prostatic Neoplasms 16461460 overexpressed 623 hsa-mir-20b Carcinoma, Hepatocellular 16331254 overexpression 624 hsa-mir-20b Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. 625 hsa-mir-20b Neoplasms 17189674 Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17¨C19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer. 626 hsa-mir-20b Schizophrenia 17326821 downregulation 627 hsa-mir-21 Brain Neoplasms 17965831 The overexpression of miR-21 was recognized in malignant brain tumours, and knockdown of this miRNA in cultured glioblastoma cells resulted in caspase activation and apoptosis. The tumour suppressor tropomyosin 1 (TPM1) was demonstrated to be a target for miR-21, explaining why inhibition of miR-21 results in reduced tumour growth. 628 hsa-mir-21 Brain Neoplasms 16466964 overexpressed 629 hsa-mir-21 Breast Neoplasms 16103053 upregulation 630 hsa-mir-21 Breast Neoplasms 17531469 MiR-21 is found to be highly expressed in numerous cancers like breast cancer, and glioblastoma and pancreatic cancer. 631 hsa-mir-21 Breast Neoplasms 16885332 Overexpression in breast cancers 632 hsa-mir-21 Breast Neoplasms 16461460 overexpressed 633 hsa-mir-21 Breast Neoplasms 16103053 upregulated 634 hsa-mir-21 Cholangiocarcinoma 17531469 Recently Meng et al. showed that miR-21 is also overexpressed in malignant cholangiocarcinomas, a highly chemoresistant cancer type, knockdown of miR-21 sensitised cholangiocarcinoma cell lines for treatment with gemcitabin, whereas transfection of non-malignant cholangiocytes with precursor miR-21 made cells more resistant to gemcitabin. 635 hsa-mir-21 Colonic Neoplasms 16461460 overexpressed 636 hsa-mir-21 Dermatitis, Atopic 17622355 miR-21 was significantly up-regulated both psoriasis (p<0.001) and atopic eczema (p<0.001) as compared with healthy skin. 637 hsa-mir-21 Focal Epithelial Hyperplasia 17478730 We found that miR-21 was one of the most upregulated miRNAs in the vascular wall after balloon injury. Our results strongly indicate that miR-21 is an important regulator for neointimal hyperplasia. 638 hsa-mir-21 Glioblastoma 16024602 upregulated 639 hsa-mir-21 Glioblastoma 17028302 miR-21 is strongly overexpressed in this highly malignant brain tumor type, while knockdown of miR-21 in glioblastoma cells by an antisense-oligonucleotide triggered activation of caspases and led to increased apoptotic cell death, suggesting that miR-21 overexpression may contribute to the malignant phenotype by suppressing critical apoptosis-related genes. 640 hsa-mir-21 Glioblastoma 16466964 overexpressed 641 hsa-mir-21 Glioblastoma 17531469 MiR-21 is found to be highly expressed in numerous cancers like breast cancer, and glioblastoma and pancreatic cancer. 642 hsa-mir-21 Glioblastoma 16885332 Elevated levels in glioblastoma primary tumors and cell lines 643 hsa-mir-21 Glioblastoma 16039986 upregulated 644 hsa-mir-21 Heart Diseases 17786230 Another miRNA consistently induced by cardiac stress, miR-21, appears to function as a regulator of cardiac growth and fetal gene activation in primary cardiomyocytes in vitro although some confusion remains regarding its exact role. 645 hsa-mir-21 Heart Failure 17606841 upregulated 646 hsa-mir-21 Lung Neoplasms 16530703 upregulation 647 hsa-mir-21 Lung Neoplasms 16461460 overexpressed 648 hsa-mir-21 Lymphoma, Large B-Cell, Diffuse 17487835 DLBCL cases over-expressed miR-21, miR-155 and miR-221 by an average of 9.3, 4.6 and 2.3-fold respectively compared to normal peripheral blood B cells. 649 hsa-mir-21 Muscular Disorders, Atrophic 17942673 Ten different miRNAs showing distinct expression patterns in the 10 different diseases (miR-21, miR-22, miR-29c, miR-30a-3p, miR-146b, miR-221, miR-368, miR-379, Ambi-miR-693, and Ambi-miR-11040). 650 hsa-mir-21 Muscular Disorders, Atrophic 17942673 dysregulation 651 hsa-mir-21 Neoplasms 17028596 mir-21 upregulated in glioblastoma and associated with antiapoptosis upregulated in breast cancer (Iorio et al., 2005), and in a signature for solid cancers (Volinia et al., 2006). 652 hsa-mir-21 Pancreatic Neoplasms 17531469 MiR-21 is found to be highly expressed in numerous cancers like breast cancer, and glioblastoma and pancreatic cancer. 653 hsa-mir-21 Pancreatic Neoplasms 16461460 overexpressed 654 hsa-mir-21 Polycythemia Vera 17976518 Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11. 655 hsa-mir-21 Prostatic Neoplasms 16461460 overexpressed 656 hsa-mir-21 Psoriasis 17622355 miR-21 was significantly up-regulated both psoriasis (p<0.001) and atopic eczema (p<0.001) as compared with healthy skin. 657 hsa-mir-21 Stomach Neoplasms 16461460 overexpressed 658 hsa-mir-210 Heart Failure 17606841 upregulated 659 hsa-mir-210 Lung Neoplasms 16530703 upregulation 660 hsa-mir-210 Muscular Disorders, Atrophic 17942673 dysregulation 661 hsa-mir-211 Heart Failure 17606841 upregulated 662 hsa-mir-212 Heart Failure 17606841 upregulated 663 hsa-mir-212 Lung Neoplasms 16530703 upregulation 664 hsa-mir-212 Schizophrenia 17326821 downregulation 665 hsa-mir-214 Cardiomyopathy, Hypertrophic 17108080 overexpressed 666 hsa-mir-214 Cardiomyopathy, Hypertrophic 17108080 miR-23a, miR-23b, miR-24, miR-195, and miR-214, all of which were up-regulated during cardiac hypertrophy, appeared to be capable of inducing hypertrophic growth in vitro. 667 hsa-mir-214 Lung Neoplasms 16530703 upregulation 668 hsa-mir-214 Muscular Disorders, Atrophic 17942673 dysregulation 669 hsa-mir-214 Pancreatic Neoplasms 16461460 overexpressed 670 hsa-mir-214 Prostatic Neoplasms 16461460 overexpressed 671 hsa-mir-214 Stomach Neoplasms 16461460 overexpressed 672 hsa-mir-215 Heart Failure 17606841 upregulated 673 hsa-mir-215 Uterine Cervical Neoplasms 17470785 The list of miRNAs at or near sites commonly altered in human cancers includes mir-215 and mir-194-1, which are <0.17 kb from D1Mit208, a marker that defines the peak of the colon Scc3 locus on Chr 1. Homologous human miRNAs are located inside the FRA1H at Chr 1q42.1; this fragile site is an HPV16 integration site involved in cervical cancer. 674 hsa-mir-216a Lung Neoplasms 16530703 downregulation 675 hsa-mir-216b Lung Neoplasms 16530703 downregulation 676 hsa-mir-218-1 Heart Failure 17606841 downregulated 677 hsa-mir-218-2 Heart Failure 17606841 downregulated 678 hsa-mir-218-2 Lung Neoplasms 16530703 downregulation 679 hsa-mir-218-2 Lung Neoplasms 17028596 mir-218-2 downregulated in lung cancer (Yanaihara et al., 2006) 680 hsa-mir-219-1 Lung Neoplasms 16530703 downregulation 681 hsa-mir-22 Heart Failure 17606841 downregulated 682 hsa-mir-22 Muscular Disorders, Atrophic 17942673 Ten different miRNAs showing distinct expression patterns in the 10 different diseases (miR-21, miR-22, miR-29c, miR-30a-3p, miR-146b, miR-221, miR-368, miR-379, Ambi-miR-693, and Ambi-miR-11040). 683 hsa-mir-22 Thyroid Neoplasms 17012848 Mir-221, mir-22 and mir-146 are significantly upregulated in this disease, whereas the expression of their predicted target gene KIT is lost, concurrently with the miRNA upregulation. 684 hsa-mir-22 Thyroid Neoplasms 17965831 Numerous miRNAs are also up-regulated in papillary thyroid carcinoma, including miR-221, miR-22 and miR-146. This up-regulation was associated with a downregulation in the expression of the oncogene KIT, a tyrosine kinase important for the control of cell proliferation. 685 hsa-mir-221 Colonic Neoplasms 16461460 overexpressed 686 hsa-mir-221 Leukemia, Lymphocytic, Chronic, B-Cell 16251535 overexpression 687 hsa-mir-221 Lymphoma, Large B-Cell, Diffuse 17487835 DLBCL cases over-expressed miR-21, miR-155 and miR-221 by an average of 9.3, 4.6 and 2.3-fold respectively compared to normal peripheral blood B cells. 688 hsa-mir-221 Muscular Disorders, Atrophic 17942673 Ten different miRNAs showing distinct expression patterns in the 10 different diseases (miR-21, miR-22, miR-29c, miR-30a-3p, miR-146b, miR-221, miR-368, miR-379, Ambi-miR-693, and Ambi-miR-11040). 689 hsa-mir-221 Muscular Disorders, Atrophic 17942673 dysregulation 690 hsa-mir-221 Pancreatic Neoplasms 16461460 overexpressed 691 hsa-mir-221 Papilary thyroid carcinoma 16728577 upregulation 692 hsa-mir-221 Papilary thyroid carcinoma 16365291 upregulation 693 hsa-mir-221 Polycythemia Vera 17976518 Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11. 694 hsa-mir-221 Stomach Neoplasms 16461460 overexpressed 695 hsa-mir-221 Thyroid Neoplasms 17355635 Recent studies in miRNA deregulation PTC found an aberrant miRNA expression profile in PTCs compared to normal thyroid tissues. In particular, a significant increase in mir-222, mir-221, mir-146. 696 hsa-mir-221 Thyroid Neoplasms 17012848 Mir-221, mir-22 and mir-146 are significantly upregulated in this disease, whereas the expression of their predicted target gene KIT is lost, concurrently with the miRNA upregulation. 697 hsa-mir-221 Thyroid Neoplasms 16885332 It was shown that miR-221, highly overexpressed in papillary thyroid tumors, is also overexpressed in normal thyroid tissue adjacent to tumors but not in normal thyroid tissues from individuals without clinical thyroid disease. 698 hsa-mir-221 Thyroid Neoplasms 17028596 Upregulated mir-221/222 in papillary thyroid cancer 699 hsa-mir-221 Thyroid Neoplasms 17965831 Numerous miRNAs are also up-regulated in papillary thyroid carcinoma, including miR-221, miR-22 and miR-146. This up-regulation was associated with a downregulation in the expression of the oncogene KIT, a tyrosine kinase important for the control of cell proliferation. 700 hsa-mir-221 Thyroid Neoplasms 17468766 somatic mutations altering binding sites for miR-221, miR-222 and miR-146 have been observed in the 3?? UTR of the KIT oncogene in papillary thyroid carcinoma. 701 hsa-mir-222 Muscular Disorders, Atrophic 17942673 dysregulation 702 hsa-mir-222 Papilary thyroid carcinoma 16728577 upregulation 703 hsa-mir-222 Polycythemia Vera 17976518 Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11. 704 hsa-mir-222 Thyroid Neoplasms 17355635 Recent studies in miRNA deregulation PTC found an aberrant miRNA expression profile in PTCs compared to normal thyroid tissues. In particular, a significant increase in mir-222, mir-221, mir-146. 705 hsa-mir-222 Thyroid Neoplasms 16885332 up-regulation 706 hsa-mir-222 Thyroid Neoplasms 17468766 somatic mutations altering binding sites for miR-221, miR-222 and miR-146 have been observed in the 3?? UTR of the KIT oncogene in papillary thyroid carcinoma. 707 hsa-mir-222 Thyroid Neoplasms 17028596 Upregulated mir-221/222 in papillary thyroid cancer 708 hsa-mir-223 Colonic Neoplasms 16461460 overexpressed 709 hsa-mir-223 Leukemia, Lymphocytic, Chronic, B-Cell 16251535 downregulated 710 hsa-mir-223 Lung Neoplasms 17028596 mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006); 711 hsa-mir-223 Muscular Disorders, Atrophic 17942673 dysregulation 712 hsa-mir-223 Pancreatic Neoplasms 16461460 overexpressed 713 hsa-mir-223 Prostatic Neoplasms 16461460 overexpressed 714 hsa-mir-223 Stomach Neoplasms 16461460 overexpressed 715 hsa-mir-224 Carcinoma, Hepatocellular 16331254 upregulated 716 hsa-mir-224 Hepatitis, Chronic 16331254 overexpression 717 hsa-mir-224 Hepatitis, Chronic 17188425 miRNA-224 regulates PDGFR expression, and decreases as disease progresses from chronic hepatitis to cirrhosis [59], suggesting that miRNA normally suppresses PDGFR in the liver until HBV integration and genetic instability upsets this balance. miRNA-224 also theoretically targets the ras-related protein, RAB-9B, which would be expected to increase as miRNA-224 levels drop off. 718 hsa-mir-224 Lung Neoplasms 16530703 downregulation 719 hsa-mir-23a Cardiomyopathy, Hypertrophic 17108080 miR-23a, miR-23b, miR-24, miR-195, and miR-214, all of which were up-regulated during cardiac hypertrophy, appeared to be capable of inducing hypertrophic growth in vitro. 720 hsa-mir-23a Cardiomyopathy, Hypertrophic 17108080 overexpressed 721 hsa-mir-23b Cardiomyopathy, Hypertrophic 17108080 miR-23a, miR-23b, miR-24, miR-195, and miR-214, all of which were up-regulated during cardiac hypertrophy, appeared to be capable of inducing hypertrophic growth in vitro. 722 hsa-mir-23b Cardiomyopathy, Hypertrophic 17108080 overexpressed 723 hsa-mir-23b Heart Failure 17606841 downregulated 724 hsa-mir-23b Leukemia, Lymphocytic, Chronic, B-Cell 16251535 overexpression 725 hsa-mir-24-1 Cardiomyopathy, Hypertrophic 17108080 miR-23a, miR-23b, miR-24, miR-195, and miR-214, all of which were up-regulated during cardiac hypertrophy, appeared to be capable of inducing hypertrophic growth in vitro. 726 hsa-mir-24-1 Cardiomyopathy, Hypertrophic 17108080 overexpressed 727 hsa-mir-24-1 Colonic Neoplasms 16461460 overexpressed 728 hsa-mir-24-1 Heart Failure 17606841 downregulated 729 hsa-mir-24-1 Leukemia, Lymphocytic, Chronic, B-Cell 16251535 overexpression 730 hsa-mir-24-1 Pancreatic Neoplasms 16461460 overexpressed 731 hsa-mir-24-1 Schizophrenia 17326821 downregulation 732 hsa-mir-24-1 Stomach Neoplasms 16461460 overexpressed 733 hsa-mir-24-1 Tourette Syndrome 17462786 A mutation in the 3'UTR of the SLITRK1 gene which is associated with Tourette's syndrome was found to enhance repression of the SLITRK mRNA by miR-189, presumably preventing SLITRK1's promotion of dendritic growth. 734 hsa-mir-24-2 Cardiomyopathy, Hypertrophic 17108080 miR-23a, miR-23b, miR-24, miR-195, and miR-214, all of which were up-regulated during cardiac hypertrophy, appeared to be capable of inducing hypertrophic growth in vitro. 735 hsa-mir-24-2 Cardiomyopathy, Hypertrophic 17108080 overexpressed 736 hsa-mir-24-2 Colonic Neoplasms 16461460 overexpressed 737 hsa-mir-24-2 Heart Failure 17606841 downregulated 738 hsa-mir-24-2 Lung Neoplasms 16530703 upregulation 739 hsa-mir-24-2 Pancreatic Neoplasms 16461460 overexpressed 740 hsa-mir-24-2 Schizophrenia 17326821 downregulation 741 hsa-mir-24-2 Stomach Neoplasms 16461460 overexpressed 742 hsa-mir-25 Pancreatic Neoplasms 16461460 overexpressed 743 hsa-mir-25 Prostatic Neoplasms 16461460 overexpressed 744 hsa-mir-25 Stomach Neoplasms 16461460 overexpressed 745 hsa-mir-26a-1 Heart Failure 17606841 upregulated 746 hsa-mir-26a-1 Lung Neoplasms 16530703 downregulation 747 hsa-mir-26a-1 Lung Neoplasms 17028596 mir-26a-1-prec downregulated in lung cancer, deleted in epithelial cancers (Yanaihara et al., 2006) 748 hsa-mir-26a-2 Heart Failure 17606841 upregulated 749 hsa-mir-26b Polycythemia Vera 17976518 Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11. 750 hsa-mir-26b Schizophrenia 17326821 downregulation 751 hsa-mir-27a Heart Failure 17606841 downregulated 752 hsa-mir-27b Leukemia, Lymphocytic, Chronic, B-Cell 16251535 mutation 753 hsa-mir-27b Lung Neoplasms 16530703 downregulation 754 hsa-mir-28 Heart Failure 17606841 upregulated 755 hsa-mir-28 Hepatitis, Chronic 16331254 downregulated 756 hsa-mir-28 Muscular Disorders, Atrophic 17942673 dysregulation 757 hsa-mir-296 Heart Failure 17606841 upregulated 758 hsa-mir-297 Heart Failure 17606841 upregulated 759 hsa-mir-299 Heart Failure 17606841 downregulated 760 hsa-mir-299 Muscular Disorders, Atrophic 17942673 dysregulation 761 hsa-mir-29a Acquired Immunodeficiency Syndrome 16236258 miRNAs expressed in T-cells can repress nef function and thus influence disease progression. 762 hsa-mir-29a Heart Failure 17606841 upregulated 763 hsa-mir-29a Leukemia, Lymphocytic, Chronic, B-Cell 16251535 downregulated 764 hsa-mir-29a Lung Neoplasms 17890317 mir-29 family (29a,b,c) reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 765 hsa-mir-29a Lung Neoplasms 17028596 mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006); 766 hsa-mir-29a Neoplasms 17965831 Many miRNAs are located at chromosomal break points or fragile sites associated with cancer. Indeed miR-29a and miR-29b are associated with the fragile site FRA7H. In addition, miR-29b along with miR-181b may target the oncogene TCL1 in CLL patients [163], while miR-29b reduced Mcl-1 protein and rendered cholangiocarcinoma cells more susceptible to apoptosis. 767 hsa-mir-29a Schizophrenia 17326821 downregulation 768 hsa-mir-29b-1 Acquired Immunodeficiency Syndrome 16236258 miRNAs expressed in T-cells can repress nef function and thus influence disease progression. 769 hsa-mir-29b-1 Breast Neoplasms 16461460 overexpressed 770 hsa-mir-29b-1 Colonic Neoplasms 16461460 overexpressed 771 hsa-mir-29b-1 Heart Failure 17606841 upregulated 772 hsa-mir-29b-1 Leukemia, Lymphocytic, Chronic, B-Cell 16251535 mutation 773 hsa-mir-29b-1 Leukemia, Lymphocytic, Chronic, B-Cell 16251535 downregulated 774 hsa-mir-29b-1 Lung Neoplasms 17890317 mir-29 family (29a,b,c) reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 775 hsa-mir-29b-1 Lung Neoplasms 16530703 downregulation 776 hsa-mir-29b-1 Lung Neoplasms 17028596 mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006); 777 hsa-mir-29b-1 Neoplasms 17965831 Many miRNAs are located at chromosomal break points or fragile sites associated with cancer. Indeed miR-29a and miR-29b are associated with the fragile site FRA7H. In addition, miR-29b along with miR-181b may target the oncogene TCL1 in CLL patients [163], while miR-29b reduced Mcl-1 protein and rendered cholangiocarcinoma cells more susceptible to apoptosis. 778 hsa-mir-29b-1 Pancreatic Neoplasms 16461460 overexpressed 779 hsa-mir-29b-1 Prostatic Neoplasms 16461460 overexpressed 780 hsa-mir-29b-1 Schizophrenia 17326821 downregulation 781 hsa-mir-29b-2 Lung Neoplasms 17028596 mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006); 782 hsa-mir-29c Leukemia, Lymphocytic, Chronic, B-Cell 16251535 downregulated 783 hsa-mir-29c Lung Neoplasms 17890317 mir-29 family (29a,b,c) reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 784 hsa-mir-29c Lung Neoplasms 17028596 mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006); 785 hsa-mir-29c Muscular Disorders, Atrophic 17942673 Ten different miRNAs showing distinct expression patterns in the 10 different diseases (miR-21, miR-22, miR-29c, miR-30a-3p, miR-146b, miR-221, miR-368, miR-379, Ambi-miR-693, and Ambi-miR-11040). 786 hsa-mir-29c Schizophrenia 17326821 downregulation 787 hsa-mir-300 Heart Failure 17606841 upregulated 788 hsa-mir-302a Heart Failure 17606841 upregulated 789 hsa-mir-302b Heart Failure 17606841 downregulated 790 hsa-mir-302b Thyroid Neoplasms 17355635 Genetically PTC is defined by several alterations which cause abnormal activation of the mitogen-activated protein kinase (MAPK) pathway, the most prevalent being point mutations in the intracellular signalling kinase BRAF. Of particular interest in this study is the downregulation of miR-323 and miR-302b in BRAF mutated cell line. miRBASE target database predicted that the BRAF transcript has binding sites for miR-323 and miR-302b to potentially bind and down- regulate BRAF expression. 791 hsa-mir-302c Heart Failure 17606841 downregulated 792 hsa-mir-30a Heart Failure 17606841 downregulated 793 hsa-mir-30a Lung Neoplasms 16530703 downregulation 794 hsa-mir-30a Lung Neoplasms 17028596 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006); 795 hsa-mir-30a Lung Neoplasms 17028596 mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006) 796 hsa-mir-30a Muscular Disorders, Atrophic 17942673 Ten different miRNAs showing distinct expression patterns in the 10 different diseases (miR-21, miR-22, miR-29c, miR-30a-3p, miR-146b, miR-221, miR-368, miR-379, Ambi-miR-693, and Ambi-miR-11040). 797 hsa-mir-30a Muscular Disorders, Atrophic 17942673 dysregulation 798 hsa-mir-30a Schizophrenia 17326821 downregulation 799 hsa-mir-30b Heart Failure 17606841 downregulated 800 hsa-mir-30b Lung Neoplasms 17028596 mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006) 801 hsa-mir-30b Schizophrenia 17326821 downregulation 802 hsa-mir-30c-1 Colonic Neoplasms 16461460 overexpressed 803 hsa-mir-30c-1 Heart Failure 17606841 downregulated 804 hsa-mir-30c-1 Lung Neoplasms 17028596 mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006) 805 hsa-mir-30c-1 Pancreatic Neoplasms 16461460 overexpressed 806 hsa-mir-30c-1 Prostatic Neoplasms 16461460 overexpressed 807 hsa-mir-30c-2 Colonic Neoplasms 16461460 overexpressed 808 hsa-mir-30c-2 Heart Failure 17606841 downregulated 809 hsa-mir-30c-2 Lung Neoplasms 17028596 mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006) 810 hsa-mir-30c-2 Pancreatic Neoplasms 16461460 overexpressed 811 hsa-mir-30c-2 Prostatic Neoplasms 16461460 overexpressed 812 hsa-mir-30d Lung Neoplasms 17028596 mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006) 813 hsa-mir-30d Neoplasms 17028596 mir-30d downregulated in six solid cancer types by SAM (Volinia et al., 2006); 814 hsa-mir-30d Schizophrenia 17326821 downregulation 815 hsa-mir-30e Heart Failure 17606841 downregulated 816 hsa-mir-30e Lung Neoplasms 17028596 mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006) 817 hsa-mir-30e Schizophrenia 17326821 downregulation 818 hsa-mir-32 Colonic Neoplasms 16461460 overexpressed 819 hsa-mir-32 Heart Failure 17606841 upregulated 820 hsa-mir-32 Lung Neoplasms 17028596 mir-32 downregulated in lung cancer (Yanaihara et al., 2006); 821 hsa-mir-32 Lung Neoplasms 16530703 downregulation 822 hsa-mir-32 Pancreatic Neoplasms 16461460 overexpressed 823 hsa-mir-32 Prostatic Neoplasms 16461460 overexpressed 824 hsa-mir-32 RNA Virus Infections 17011485 The accumulation of a retrovirus was shown to be reduced in human cells by the activity of miR-32, indicating that the miRNA machinery is exploited for defense against viruses. 825 hsa-mir-32 RNA Virus Infections 17462786 This has been reported for the retrovirus primate foamy virus-1 (PFV-1), which can be targeted by the host miR-32 [150], which was suggested to restrict its infection. 826 hsa-mir-32 RNA Virus Infections 17096367 The authors found that a cellular miRNA, miR-32, mediated antiviral defense in human cells, and regulated primate foamy virus type I (PFV-1) proliferation. 827 hsa-mir-320a Heart Failure 17606841 upregulated 828 hsa-mir-320a Muscular Disorders, Atrophic 17942673 dysregulation 829 hsa-mir-323a Thyroid Neoplasms 17355635 Genetically PTC is defined by several alterations which cause abnormal activation of the mitogen-activated protein kinase (MAPK) pathway, the most prevalent being point mutations in the intracellular signalling kinase BRAF. Of particular interest in this study is the downregulation of miR-323 and miR-302b in BRAF mutated cell line. miRBASE target database predicted that the BRAF transcript has binding sites for miR-323 and miR-302b to potentially bind and down- regulate BRAF expression. 830 hsa-mir-325 Heart Failure 17606841 downregulated 831 hsa-mir-330 Heart Failure 17606841 upregulated 832 hsa-mir-331 Prostatic Neoplasms 19584056 miR-311-3p regulate ERBB-2 expression and androgen receptor signaling in prostate cancer 833 hsa-mir-335 Muscular Disorders, Atrophic 17942673 dysregulation 834 hsa-mir-339 Heart Failure 17606841 downregulated 835 hsa-mir-33a Lung Neoplasms 16530703 downregulation 836 hsa-mir-33b Lung Neoplasms 16530703 downregulation 837 hsa-mir-340 Heart Failure 17606841 upregulated 838 hsa-mir-342 Heart Failure 17606841 downregulated 839 hsa-mir-342 Hepatitis, Chronic 16331254 downregulated 840 hsa-mir-34a Breast Neoplasms 17028596 mir-34 downregulated in breast cancer (Iorio et al., 2005) 841 hsa-mir-34a Colonic Neoplasms 17875987 highly upregulated 842 hsa-mir-34a Lung Neoplasms 17028596 mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006) 843 hsa-mir-34a Muscular Disorders, Atrophic 17942673 dysregulation 844 hsa-mir-34a Neuroblastoma 17965831 miR-34a induces apoptosis in neuroblastoma cells, possibly by targeting the transcription factor E2F3. This p53-induced up-regulation of miR-34a results in an enhanced reduction in cell proliferation, strongly suggesting that miR-34a reinforces the tumour suppressor function of p53. 845 hsa-mir-34b Breast Neoplasms 17028596 mir-34 downregulated in breast cancer (Iorio et al., 2005) 846 hsa-mir-34b Heart Failure 17606841 upregulated 847 hsa-mir-34b Lung Neoplasms 17028596 mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006) 848 hsa-mir-34c Breast Neoplasms 17028596 mir-34 downregulated in breast cancer (Iorio et al., 2005) 849 hsa-mir-34c Lung Neoplasms 17028596 mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006) 850 hsa-mir-362 Muscular Disorders, Atrophic 17942673 dysregulation 851 hsa-mir-365a Heart Failure 17606841 upregulated 852 hsa-mir-365b Heart Failure 17606841 upregulated 853 hsa-mir-367 Heart Failure 17606841 upregulated 854 hsa-mir-372 Heart Failure 17606841 upregulated 855 hsa-mir-372 Hepatitis, Chronic 16331254 downregulated 856 hsa-mir-372 Neoplasms 17028596 mir-372/373 shown to be oncogenes cooperating with Ras (Voorhoeve et al., 2006) 857 hsa-mir-372 Neoplasms 17989227 the related miR-372/373 miRNAs promote tumorigenesis in combination with oncogenic RAS, at least in part by directly inhibiting the tumor suppressor LATS2. 858 hsa-mir-372 Neoplasms, Germ Cell and Embryonal 17011485 Expression of miR-372 and miR-373 seems to be specifically associated with germ cell tumors, as most somatic tumors do not express these miRNAs. 859 hsa-mir-372 Testicular Neoplasms 17965831 miR-372 and miR-373 have been implicated in testicular germ cell tumours. 860 hsa-mir-372 Testicular Neoplasms 17189674 The relevance to human tumorigenesis was shown when it was found that these miRNAs are hyper-expressed in Testicular Germ Cell Tumors, a tumor type characterized by its prevalence of wild type p53. 861 hsa-mir-373 Heart Failure 17606841 upregulated 862 hsa-mir-373 Neoplasms 17989227 the related miR-372/373 miRNAs promote tumorigenesis in combination with oncogenic RAS, at least in part by directly inhibiting the tumor suppressor LATS2. 863 hsa-mir-373 Neoplasms 17028596 mir-372/373 shown to be oncogenes cooperating with Ras (Voorhoeve et al., 2006) 864 hsa-mir-373 Neoplasms, Germ Cell and Embryonal 17011485 Expression of miR-372 and miR-373 seems to be specifically associated with germ cell tumors, as most somatic tumors do not express these miRNAs. 865 hsa-mir-373 Testicular Neoplasms 17965831 miR-372 and miR-373 have been implicated in testicular germ cell tumours. 866 hsa-mir-373 Testicular Neoplasms 17189674 The relevance to human tumorigenesis was shown when it was found that these miRNAs are hyper-expressed in Testicular Germ Cell Tumors, a tumor type characterized by its prevalence of wild type p53. 867 hsa-mir-375 Diabetes Mellitus 17965831 For instance, miR-375 was shown to directly regulate insulin secretion from pancreatic islet cells. Overexpression of miR-375 led to an enhanced inhibition of insulin exocytosis, whereas anti-sense to miR-375 enhanced insulin secretion by blocking the effects of the miRNA. 868 hsa-mir-375 Diabetes Mellitus 16195701 mir-375 was found to modulate glucose-stimulated insulin secretion and exocytosis. 869 hsa-mir-376c Hepatitis, Chronic 16331254 downregulated 870 hsa-mir-376c Muscular Disorders, Atrophic 17942673 Ten different miRNAs showing distinct expression patterns in the 10 different diseases (miR-21, miR-22, miR-29c, miR-30a-3p, miR-146b, miR-221, miR-368, miR-379, Ambi-miR-693, and Ambi-miR-11040). 871 hsa-mir-376c Muscular Disorders, Atrophic 17942673 dysregulation 872 hsa-mir-377 Heart Failure 17606841 upregulated 873 hsa-mir-378a Polycythemia Vera 17976518 Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11. 874 hsa-mir-379 Muscular Disorders, Atrophic 17942673 Ten different miRNAs showing distinct expression patterns in the 10 different diseases (miR-21, miR-22, miR-29c, miR-30a-3p, miR-146b, miR-221, miR-368, miR-379, Ambi-miR-693, and Ambi-miR-11040). 875 hsa-mir-379 Muscular Disorders, Atrophic 17942673 dysregulation 876 hsa-mir-381 Heart Failure 17606841 upregulated 877 hsa-mir-381 Muscular Disorders, Atrophic 17942673 dysregulation 878 hsa-mir-382 Heart Failure 17606841 upregulated 879 hsa-mir-423 Heart Failure 17606841 upregulated 880 hsa-mir-424 Heart Failure 17606841 upregulated 881 hsa-mir-429 Heart Failure 17606841 upregulated 882 hsa-mir-432 Heart Failure 17606841 upregulated 883 hsa-mir-432 Muscular Disorders, Atrophic 17942673 dysregulation 884 hsa-mir-451a Polycythemia Vera 17976518 Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11. 885 hsa-mir-452 Heart Failure 17606841 downregulated 886 hsa-mir-452 Muscular Disorders, Atrophic 17942673 dysregulation 887 hsa-mir-487b Muscular Disorders, Atrophic 17942673 dysregulation 888 hsa-mir-494 Heart Failure 17606841 downregulated 889 hsa-mir-495 Muscular Disorders, Atrophic 17942673 dysregulation 890 hsa-mir-497 Heart Failure 17606841 downregulated 891 hsa-mir-497 Muscular Disorders, Atrophic 17942673 dysregulation 892 hsa-mir-499a Heart Failure 17606841 downregulated 893 hsa-mir-500a Heart Failure 17606841 upregulated 894 hsa-mir-501 Muscular Disorders, Atrophic 17942673 dysregulation 895 hsa-mir-507 Heart Failure 17606841 downregulated 896 hsa-mir-512-1 Heart Failure 17606841 downregulated 897 hsa-mir-512-2 Heart Failure 17606841 downregulated 898 hsa-mir-515-1 Heart Failure 17606841 downregulated 899 hsa-mir-515-2 Heart Failure 17606841 downregulated 900 hsa-mir-520a Heart Failure 17606841 downregulated 901 hsa-mir-520b Heart Failure 17606841 downregulated 902 hsa-mir-520c Heart Failure 17606841 upregulated 903 hsa-mir-520c Heart Failure 17606841 downregulated 904 hsa-mir-520d Heart Failure 17606841 downregulated 905 hsa-mir-520e Heart Failure 17606841 downregulated 906 hsa-mir-520f Heart Failure 17606841 downregulated 907 hsa-mir-520g Heart Failure 17606841 downregulated 908 hsa-mir-520h Heart Failure 17606841 downregulated 909 hsa-mir-523 Heart Failure 17606841 downregulated 910 hsa-mir-525 Heart Failure 17606841 upregulated 911 hsa-mir-526a-1 Heart Failure 17606841 downregulated 912 hsa-mir-526a-2 Heart Failure 17606841 downregulated 913 hsa-mir-526b Heart Failure 17606841 downregulated 914 hsa-mir-7-1 Schizophrenia 17326821 downregulation 915 hsa-mir-7-2 Schizophrenia 17326821 downregulation 916 hsa-mir-7-3 Schizophrenia 17326821 downregulation 917 hsa-mir-9-1 Breast Neoplasms 17028596 mir-9 increased in breast cancers (Iorio et al., 2005), but downregulated in lung cancers (Yanaihara et al., 2006) 918 hsa-mir-9-1 Lung Neoplasms 16530703 downregulation 919 hsa-mir-9-1 Schizophrenia 17326821 downregulation 920 hsa-mir-9-2 Breast Neoplasms 17028596 mir-9 increased in breast cancers (Iorio et al., 2005), but downregulated in lung cancers (Yanaihara et al., 2006) 921 hsa-mir-9-2 Lung Neoplasms 16530703 downregulation 922 hsa-mir-9-2 Schizophrenia 17326821 downregulation 923 hsa-mir-92a-1 Carcinoma, Hepatocellular 16331254 overexpression 924 hsa-mir-92a-1 Colonic Neoplasms 17965831 The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation. 925 hsa-mir-92a-1 Hematologic Neoplasms 17011485 The miR-17-92 cluster is amplified in hematopoietic malignancies. 926 hsa-mir-92a-1 Leukemia, B-Cell 16224045 Overexpression 927 hsa-mir-92a-1 Leukemia, B-Cell 15944707 overexpression 928 hsa-mir-92a-1 Leukemia, B-Cell 17940623 These data suggested a direct involvement of this miRNA cluster in tumorigenesis. The miR-17-92 cluster encompassing six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1. 929 hsa-mir-92a-1 Leukemia, B-Cell 16736018 upregulation of miR-155 and the miR-17-92 cluster 930 hsa-mir-92a-1 Lung Neoplasms 17965831 The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation. 931 hsa-mir-92a-1 Lung Neoplasms 16885332 Overexpressed in lung cancers 932 hsa-mir-92a-1 Lung Neoplasms 16266980 overexpressed 933 hsa-mir-92a-1 Lymphoma 16885332 Primary transcripts overexpressed in lymphomas 934 hsa-mir-92a-1 Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. 935 hsa-mir-92a-1 Neoplasms 17028596 mir-92 downregulated in six solid cancer types by PAM (Volinia et al., 2006) 936 hsa-mir-92a-1 Schizophrenia 17326821 downregulation 937 hsa-mir-92a-2 Carcinoma, Hepatocellular 16331254 overexpression 938 hsa-mir-92a-2 Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. 939 hsa-mir-92a-2 Neoplasms 17028596 mir-92 downregulated in six solid cancer types by PAM (Volinia et al., 2006) 940 hsa-mir-92a-2 Schizophrenia 17326821 downregulation 941 hsa-mir-92b Carcinoma, Hepatocellular 16331254 overexpression 942 hsa-mir-92b Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. 943 hsa-mir-92b Neoplasms 17028596 mir-92 downregulated in six solid cancer types by PAM (Volinia et al., 2006) 944 hsa-mir-92b Schizophrenia 17326821 downregulation 945 hsa-mir-9-3 Breast Neoplasms 17028596 mir-9 increased in breast cancers (Iorio et al., 2005), but downregulated in lung cancers (Yanaihara et al., 2006) 946 hsa-mir-9-3 Lung Neoplasms 16530703 downregulation 947 hsa-mir-9-3 Schizophrenia 17326821 downregulation 948 hsa-mir-95 Lung Neoplasms 16530703 downregulation 949 hsa-mir-98 Heart Failure 17606841 upregulated 950 hsa-mir-98 Neoplasms 17028596 Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control. 951 hsa-mir-99b Carcinoma, Hepatocellular 17188425 Independent observations showed that the expression of miRNAs let-7e, 125a and 99b, located at 19q13.4, were considerably lower in HCC compared to nontumor liver [59] and [65]. Given that miRNA-125a targets expression of the mitochondrial tumor suppressor gene, MTSG1, and RAR|á, chromosomal instability in and around FRA19A may extinguish expression of these tumor suppressor genes. 952 hsa-mir-99b Muscular Disorders, Atrophic 17942673 dysregulation 953 hsa-mir-22 Lymphoma, B-Cell 18066065 c-Myc repressed this miRNA 954 hsa-mir-29c Lymphoma, B-Cell 18066065 c-Myc repressed this miRNA 955 hsa-mir-30e Lymphoma, B-Cell 18066065 c-Myc repressed this miRNA 956 hsa-mir-146a Lymphoma, B-Cell 18066065 c-Myc repressed this miRNA 957 hsa-mir-150 Lymphoma, B-Cell 18066065 c-Myc repressed this miRNA 958 hsa-mir-15a Lymphoma, B-Cell 18066065 c-Myc repressed this miRNA 959 hsa-mir-29a Lymphoma, B-Cell 18066065 c-Myc repressed this miRNA 960 hsa-mir-34a Lymphoma, B-Cell 18066065 c-Myc repressed this miRNA 961 hsa-mir-195 Lymphoma, B-Cell 18066065 c-Myc repressed this miRNA 962 hsa-mir-26b Lymphoma, B-Cell 18066065 c-Myc repressed this miRNA 963 hsa-let-7g Schizophrenia 18184693 upregulated 964 hsa-mir-107 Alzheimer Disease 18234899 downregulated 965 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 18362358 lost or downregulated 966 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 18362358 lost or downregulated 967 hsa-mir-155 Burkitt Lymphoma 18354490 process BIC 968 hsa-mir-146a Burkitt Lymphoma 18347435 induced by EBV-encoded latent membrane protein 1 (LMP1) 969 hsa-mir-155 Burkitt Lymphoma 18347435 induced by EBV-encoded latent membrane protein 1 (LMP1) 970 hsa-mir-200a Neoplasms 18381893 the epithelial-to-mesenchymal transition 971 hsa-mir-200b Neoplasms 18381893 the epithelial-to-mesenchymal transition 972 hsa-mir-200c Neoplasms 18381893 the epithelial-to-mesenchymal transition 973 hsa-mir-29c Nasopharyngeal Neoplasms 18390668 down-regulated 974 hsa-mir-29a Alzheimer Disease 18434550 loss 975 hsa-mir-29b-1 Alzheimer Disease 18434550 loss 976 hsa-mir-200a Breast Neoplasms 18376396 downregulated 977 hsa-mir-200b Breast Neoplasms 18376396 downregulated 978 hsa-mir-200c Breast Neoplasms 18376396 downregulated 979 hsa-mir-141 Breast Neoplasms 18376396 downregulated 980 hsa-mir-429 Breast Neoplasms 18376396 downregulated 981 hsa-mir-205 Breast Neoplasms 18376396 downregulated 982 hsa-mir-106a Retinal Neovascularization 18500251 decreased 983 hsa-mir-214 Retinal Neovascularization 18500251 decreased 984 hsa-mir-424 Retinal Neovascularization 18500251 decreased 985 hsa-mir-31 Retinal Neovascularization 18500251 increased 986 hsa-mir-150 Retinal Neovascularization 18500251 increased 987 hsa-mir-184 Retinal Neovascularization 18500251 increased 988 hsa-mir-106a Retinal Neovascularization 18500251 increased 989 hsa-mir-214 Retinal Neovascularization 18500251 increased 990 hsa-mir-424 Retinal Neovascularization 18500251 increased 991 hsa-mir-451a Retinal Neovascularization 18500251 increased 992 hsa-mir-31 Retinal Neovascularization 18500251 mir-31-prec decreased 993 hsa-mir-150 Retinal Neovascularization 18500251 decreased 994 hsa-mir-184 Retinal Neovascularization 18500251 decreased 995 hsa-mir-127 Leukemia, Myeloid, Acute 18478077 deregulation 996 hsa-mir-154 Leukemia, Myeloid, Acute 18478077 deregulation 997 hsa-mir-299 Leukemia, Myeloid, Acute 18478077 deregulation 998 hsa-mir-323a Leukemia, Myeloid, Acute 18478077 deregulation 999 hsa-mir-370 Leukemia, Myeloid, Acute 18478077 deregulation 1000 hsa-mir-19a Hamartoma Syndrome, Multiple 18460397 overexpressed 1001 hsa-mir-21 Hamartoma Syndrome, Multiple 18460397 overexpressed 1002 hsa-mir-21 Ovarian Neoplasms 18451233 normal 1003 hsa-mir-125a Ovarian Neoplasms 18451233 normal 1004 hsa-mir-100 Ovarian Neoplasms 18451233 normal 1005 hsa-mir-145 Ovarian Neoplasms 18451233 normal 1006 hsa-mir-99a Ovarian Neoplasms 18451233 normal 1007 hsa-mir-141 Ovarian Neoplasms 18451233 Higher 1008 hsa-mir-18a Ovarian Neoplasms 18451233 Higher 1009 hsa-mir-93 Ovarian Neoplasms 18451233 Higher 1010 hsa-mir-429 Ovarian Neoplasms 18451233 Higher 1011 hsa-let-7b Ovarian Neoplasms 18451233 lower 1012 hsa-mir-146a Eczema 18419608 upregulation 1013 hsa-mir-181a-1 Leukemia, Myeloid, Acute 18450603 deregulation 1014 hsa-mir-181a-2 Leukemia, Myeloid, Acute 18450603 deregulation 1015 hsa-mir-181c Leukemia, Myeloid, Acute 18450603 deregulation 1016 hsa-mir-181d Leukemia, Myeloid, Acute 18450603 deregulation 1017 hsa-mir-191 Neoplasms 18375788 increased 1018 hsa-mir-29b-1 Alzheimer Disease 18434550 decreased 1019 hsa-mir-223 Ovarian Neoplasms 18442408 dysregulated 1020 hsa-mir-199a-1 Neoplasms 18430245 decreased 1021 hsa-mir-221 Melanoma 18417445 suppressing 1022 hsa-mir-222 Melanoma 18417445 suppressing 1023 hsa-mir-155 Myeloproliferative Disorders 18299402 Sustained expression 1024 hsa-mir-10b Neoplasms 18256538 pro-metastatic 1025 hsa-mir-107 Alzheimer Disease 18234899 decreases 1026 hsa-mir-210 Breast Neoplasms 18316553 induced 1027 hsa-mir-433 Parkinson Disease 18252210 Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. 1028 hsa-mir-212 Liver Diseases, Alcoholic 18162065 increased 1029 hsa-mir-128-2 Lung Neoplasms 18304967 increased 1030 hsa-mir-96 Hodgkin Disease 18089852 down-regulated 1031 hsa-mir-128-1 Hodgkin Disease 18089852 down-regulated 1032 hsa-mir-128-2 Hodgkin Disease 18089852 down-regulated 1033 hsa-mir-155 Pancreatic Neoplasms 17911264 overexpressed 1034 hsa-mir-21 Carcinoma, Hepatocellular 18223217 increased 1035 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 17941951 altered expression 1036 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 17941951 altered expression 1037 hsa-let-7a-3 Ovarian Neoplasms 17974952 decreased 1038 hsa-mir-150 Polycythemia Vera 17976518 downregulation 1039 hsa-mir-155 Polycythemia Vera 17976518 downregulation 1040 hsa-mir-221 Polycythemia Vera 17976518 downregulation 1041 hsa-mir-222 Polycythemia Vera 17976518 downregulation 1042 hsa-mir-451a Polycythemia Vera 17976518 upregulation 1043 hsa-mir-339 Polycythemia Vera 17976518 biphasic regulation 1044 hsa-mir-378a Polycythemia Vera 17976518 biphasic regulation 1045 hsa-mir-296 Ovarian Neoplasms 16754881 copy number gain 1046 hsa-mir-1-1 Ovarian Neoplasms 16754881 copy number gain 1047 hsa-mir-133a-2 Ovarian Neoplasms 16754881 copy number gain 1048 hsa-mir-153-2 Ovarian Neoplasms 16754881 copy number gain 1049 hsa-mir-339 Ovarian Neoplasms 16754881 copy number gain 1050 hsa-mir-103a-2 Ovarian Neoplasms 16754881 copy number gain 1051 hsa-mir-106b Ovarian Neoplasms 16754881 copy number gain 1052 hsa-mir-25 Ovarian Neoplasms 16754881 copy number gain 1053 hsa-mir-93 Ovarian Neoplasms 16754881 copy number gain 1054 hsa-mir-219-1 Ovarian Neoplasms 16754881 copy number gain 1055 hsa-mir-135b Ovarian Neoplasms 16754881 copy number gain 1056 hsa-mir-194-1 Ovarian Neoplasms 16754881 copy number gain 1057 hsa-mir-215 Ovarian Neoplasms 16754881 copy number gain 1058 hsa-mir-338 Ovarian Neoplasms 16754881 copy number gain 1059 hsa-mir-199a-2 Ovarian Neoplasms 16754881 copy number gain 1060 hsa-mir-214 Ovarian Neoplasms 16754881 copy number gain 1061 hsa-mir-151a Ovarian Neoplasms 16754881 copy number gain 1062 hsa-mir-30b Ovarian Neoplasms 16754881 copy number gain 1063 hsa-mir-30d Ovarian Neoplasms 16754881 copy number gain 1064 hsa-mir-200a Ovarian Neoplasms 16754881 copy number gain 1065 hsa-mir-200b Ovarian Neoplasms 16754881 copy number gain 1066 hsa-mir-429 Ovarian Neoplasms 16754881 copy number gain 1067 hsa-mir-9-1 Ovarian Neoplasms 16754881 copy number gain 1068 hsa-mir-488 Ovarian Neoplasms 16754881 copy number gain 1069 hsa-mir-296 Breast Neoplasms 16754881 copy number gain 1070 hsa-mir-1-1 Breast Neoplasms 16754881 copy number gain 1071 hsa-mir-133a-2 Breast Neoplasms 16754881 copy number gain 1072 hsa-mir-153-2 Breast Neoplasms 16754881 copy number gain 1073 hsa-mir-339 Breast Neoplasms 16754881 copy number gain 1074 hsa-mir-103a-2 Breast Neoplasms 16754881 copy number gain 1075 hsa-mir-106b Breast Neoplasms 16754881 copy number gain 1076 hsa-mir-25 Breast Neoplasms 16754881 copy number gain 1077 hsa-mir-93 Breast Neoplasms 16754881 copy number gain 1078 hsa-mir-219-1 Breast Neoplasms 16754881 copy number gain 1079 hsa-mir-135b Breast Neoplasms 16754881 copy number gain 1080 hsa-mir-194-1 Breast Neoplasms 16754881 copy number gain 1081 hsa-mir-215 Breast Neoplasms 16754881 copy number gain 1082 hsa-mir-338 Breast Neoplasms 16754881 copy number gain 1083 hsa-mir-199a-2 Breast Neoplasms 16754881 copy number gain 1084 hsa-mir-214 Breast Neoplasms 16754881 copy number gain 1085 hsa-mir-151a Breast Neoplasms 16754881 copy number gain 1086 hsa-mir-30b Breast Neoplasms 16754881 copy number gain 1087 hsa-mir-30d Breast Neoplasms 16754881 copy number gain 1088 hsa-mir-200a Breast Neoplasms 16754881 copy number gain 1089 hsa-mir-200b Breast Neoplasms 16754881 copy number gain 1090 hsa-mir-429 Breast Neoplasms 16754881 copy number gain 1091 hsa-mir-9-1 Breast Neoplasms 16754881 copy number gain 1092 hsa-mir-488 Breast Neoplasms 16754881 copy number gain 1093 hsa-mir-296 Melanoma 16754881 copy number gain 1094 hsa-mir-1-1 Melanoma 16754881 copy number gain 1095 hsa-mir-133a-2 Melanoma 16754881 copy number gain 1096 hsa-mir-153-2 Melanoma 16754881 copy number gain 1097 hsa-mir-339 Melanoma 16754881 copy number gain 1098 hsa-mir-103a-2 Melanoma 16754881 copy number gain 1099 hsa-mir-106b Melanoma 16754881 copy number gain 1100 hsa-mir-25 Melanoma 16754881 copy number gain 1101 hsa-mir-93 Melanoma 16754881 copy number gain 1102 hsa-mir-219-1 Melanoma 16754881 copy number gain 1103 hsa-mir-135b Melanoma 16754881 copy number gain 1104 hsa-mir-194-1 Melanoma 16754881 copy number gain 1105 hsa-mir-215 Melanoma 16754881 copy number gain 1106 hsa-mir-338 Melanoma 16754881 copy number gain 1107 hsa-mir-199a-2 Melanoma 16754881 copy number gain 1108 hsa-mir-214 Melanoma 16754881 copy number gain 1109 hsa-mir-151a Melanoma 16754881 copy number gain 1110 hsa-mir-30b Melanoma 16754881 copy number gain 1111 hsa-mir-30d Melanoma 16754881 copy number gain 1112 hsa-mir-200a Melanoma 16754881 copy number gain 1113 hsa-mir-200b Melanoma 16754881 copy number gain 1114 hsa-mir-429 Melanoma 16754881 copy number gain 1115 hsa-mir-9-1 Melanoma 16754881 copy number gain 1116 hsa-mir-488 Melanoma 16754881 copy number gain 1117 hsa-mir-302a Melanoma 16754881 copy number loss 1118 hsa-mir-302b Melanoma 16754881 copy number loss 1119 hsa-mir-302c Melanoma 16754881 copy number loss 1120 hsa-mir-302d Melanoma 16754881 copy number loss 1121 hsa-mir-367 Melanoma 16754881 copy number loss 1122 hsa-mir-218-1 Melanoma 16754881 copy number loss 1123 hsa-mir-383 Melanoma 16754881 copy number loss 1124 hsa-mir-17 Melanoma 16754881 copy number loss 1125 hsa-mir-18a Melanoma 16754881 copy number loss 1126 hsa-mir-19a Melanoma 16754881 copy number loss 1127 hsa-mir-19b-1 Melanoma 16754881 copy number loss 1128 hsa-mir-20a Melanoma 16754881 copy number loss 1129 hsa-mir-320a Melanoma 16754881 copy number loss 1130 hsa-mir-302a Breast Neoplasms 16754881 copy number loss 1131 hsa-mir-302b Breast Neoplasms 16754881 copy number loss 1132 hsa-mir-302c Breast Neoplasms 16754881 copy number loss 1133 hsa-mir-302d Breast Neoplasms 16754881 copy number loss 1134 hsa-mir-367 Breast Neoplasms 16754881 copy number loss 1135 hsa-mir-218-1 Breast Neoplasms 16754881 copy number loss 1136 hsa-mir-383 Breast Neoplasms 16754881 copy number loss 1137 hsa-mir-17 Breast Neoplasms 16754881 copy number loss 1138 hsa-mir-18a Breast Neoplasms 16754881 copy number loss 1139 hsa-mir-19a Breast Neoplasms 16754881 copy number loss 1140 hsa-mir-19b-1 Breast Neoplasms 16754881 copy number loss 1141 hsa-mir-20a Breast Neoplasms 16754881 copy number loss 1142 hsa-mir-320a Breast Neoplasms 16754881 copy number loss 1143 hsa-mir-302a Ovarian Neoplasms 16754881 copy number loss 1144 hsa-mir-302b Ovarian Neoplasms 16754881 copy number loss 1145 hsa-mir-302c Ovarian Neoplasms 16754881 copy number loss 1146 hsa-mir-302d Ovarian Neoplasms 16754881 copy number loss 1147 hsa-mir-367 Ovarian Neoplasms 16754881 copy number loss 1148 hsa-mir-218-1 Ovarian Neoplasms 16754881 copy number loss 1149 hsa-mir-383 Ovarian Neoplasms 16754881 copy number loss 1150 hsa-mir-17 Ovarian Neoplasms 16754881 copy number loss 1151 hsa-mir-18a Ovarian Neoplasms 16754881 copy number loss 1152 hsa-mir-19a Ovarian Neoplasms 16754881 copy number loss 1153 hsa-mir-19b-1 Ovarian Neoplasms 16754881 copy number loss 1154 hsa-mir-20a Ovarian Neoplasms 16754881 copy number loss 1155 hsa-mir-320a Ovarian Neoplasms 16754881 copy number loss 1156 hsa-let-7a-1 ACTH-Secreting Pituitary Adenoma 18840638 let-7a: deregulation 1157 hsa-let-7a-2 ACTH-Secreting Pituitary Adenoma 18840638 let-7a: deregulation 1158 hsa-let-7a-3 ACTH-Secreting Pituitary Adenoma 18840638 let-7a: deregulation 1159 hsa-mir-141 ACTH-Secreting Pituitary Adenoma 18840638 miR-141: deregulation 1160 hsa-mir-143 ACTH-Secreting Pituitary Adenoma 18840638 miR-143: deregulation 1161 hsa-mir-145 ACTH-Secreting Pituitary Adenoma 18840638 miR-145: deregulation 1162 hsa-mir-150 ACTH-Secreting Pituitary Adenoma 18840638 miR-150: deregulation 1163 hsa-mir-15a ACTH-Secreting Pituitary Adenoma 18840638 miR-15a: deregulation 1164 hsa-mir-16-1 ACTH-Secreting Pituitary Adenoma 18840638 miR-16: deregulation 1165 hsa-mir-16-2 ACTH-Secreting Pituitary Adenoma 18840638 miR-16: deregulation 1166 hsa-mir-21 ACTH-Secreting Pituitary Adenoma 18840638 miR-21: deregulation 1167 hsa-mir-223 Precursor Cell Lymphoblastic Leukemia-Lymphoma 19148136 miR-223: regulated by Glucocorticoids (GCs) 1168 hsa-mir-125b-1 Leukemia, Myeloid, Acute 18936236 miR-125b-1: Myeloid cell differentiation arrest by miR-125b-1 1169 hsa-mir-126 Leukemia, Myeloid, Acute 18832181 miR-126: discriminate CBF, t(15;17), and MLL-rearrangement AMLs 1170 hsa-mir-126 Leukemia, Myeloid, Acute 18832181 miR-126*: discriminate CBF, t(15;17), and MLL-rearrangement AMLs 1171 hsa-mir-17 Leukemia, Myeloid, Acute 18832181 miR-17-5p: discriminate CBF, t(15;17), and MLL-rearrangement AMLs 1172 hsa-mir-20a Leukemia, Myeloid, Acute 18832181 miR-20a: discriminate CBF, t(15;17), and MLL-rearrangement AMLs 1173 hsa-mir-224 Leukemia, Myeloid, Acute 18832181 miR-224: discriminate CBF, t(15;17), and MLL-rearrangement AMLs 1174 hsa-mir-29b-1 Leukemia, Myeloid, Acute 19211935 miR-29b: induces global DNA hypomethylation and tumor suppressor gene re-expression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1 1175 hsa-mir-29b-2 Leukemia, Myeloid, Acute 19211935 miR-29b: induces global DNA hypomethylation and tumor suppressor gene re-expression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1 1176 hsa-mir-34b Leukemia, Myeloid, Acute 19258499 miR-34b: miR-34b targets cyclic AMP-responsive element binding protein 1177 hsa-mir-382 Leukemia, Myeloid, Acute 18832181 miR-382: discriminate CBF, t(15;17), and MLL-rearrangement AMLs 1178 hsa-mir-34a Leukemia, Promyelocytic, Acute 19151778 miR-34: that enforced expression of miR-342 in APL cells stimulated ATRA-induced differentiation 1179 hsa-mir-34b Leukemia, Promyelocytic, Acute 19151778 miR-34: that enforced expression of miR-342 in APL cells stimulated ATRA-induced differentiation 1180 hsa-mir-34c Leukemia, Promyelocytic, Acute 19151778 miR-34: that enforced expression of miR-342 in APL cells stimulated ATRA-induced differentiation 1181 hsa-mir-17 Precursor Cell Lymphoblastic Leukemia-Lymphoma 19347736 miR-17-5p: down-regulated 1182 hsa-mir-29a Precursor Cell Lymphoblastic Leukemia-Lymphoma 19347736 miR-29: down-regulated 1183 hsa-mir-29b-1 Precursor Cell Lymphoblastic Leukemia-Lymphoma 19347736 miR-29: down-regulated 1184 hsa-mir-29b-2 Precursor Cell Lymphoblastic Leukemia-Lymphoma 19347736 miR-29: down-regulated 1185 hsa-mir-29c Precursor Cell Lymphoblastic Leukemia-Lymphoma 19347736 miR-29: down-regulated 1186 hsa-mir-34a Precursor Cell Lymphoblastic Leukemia-Lymphoma 19347736 miR-34a: down-regulated 1187 hsa-mir-198 Acquired Immunodeficiency Syndrome 19148268 miR-198: miR-198 inhibits HIV-1 gene expression and replication in monocytes 1188 hsa-mir-29a Acquired Immunodeficiency Syndrome 19102781 miR-29a: Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication 1189 hsa-mir-106b Alzheimer Disease 19110058 miR-106b: endogenous regulators of APP expression 1190 hsa-mir-146a Alzheimer Disease 18801740 miR-146a: An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells 1191 hsa-mir-17 Alzheimer Disease 19110058 miR-17-5p: endogenous regulators of APP expression 1192 hsa-mir-20a Alzheimer Disease 19110058 miR-20a: endogenous regulators of APP expression 1193 hsa-mir-221 Prostatic Neoplasms 19351832 miR-221: Overexpression 1194 hsa-mir-222 Prostatic Neoplasms 19351832 miR-222: Overexpression 1195 hsa-mir-181b-1 Astrocytoma 19159078 miR-181b: downregulation 1196 hsa-mir-181b-2 Astrocytoma 19159078 miR-181b: downregulation 1197 hsa-mir-21 Astrocytoma 19159078 miR-21: upregulation 1198 hsa-mir-221 Astrocytoma 19159078 miR-221: upregulation 1199 hsa-mir-106a Autistic Disorder 18563458 miR-106a: deregulation 1200 hsa-mir-106b Autistic Disorder 18563458 miR-106b: deregulation 1201 hsa-mir-129-1 Autistic Disorder 18563458 miR-129: deregulation 1202 hsa-mir-129-2 Autistic Disorder 18563458 miR-129: deregulation 1203 hsa-mir-132 Autistic Disorder 18563458 miR-132: deregulation 1204 hsa-mir-132 Autistic Disorder 19360674 miR-132: upregulated 1205 hsa-mir-140 Autistic Disorder 18563458 miR-140: deregulation 1206 hsa-mir-146a Autistic Disorder 19360674 miR-146a: upregulated 1207 hsa-mir-146b Autistic Disorder 18563458 miR-146b: deregulation 1208 hsa-mir-146b Autistic Disorder 19360674 mir-146b: upregulated 1209 hsa-mir-148b Autistic Disorder 18563458 miR-148b: deregulation 1210 hsa-mir-15a Autistic Disorder 18563458 miR-15a: deregulation 1211 hsa-mir-15b Autistic Disorder 18563458 miR-15b: deregulation 1212 hsa-mir-181d Autistic Disorder 18563458 miR-181d: deregulation 1213 hsa-mir-193b Autistic Disorder 18563458 miR-193b: deregulation 1214 hsa-mir-21 Autistic Disorder 18563458 miR-21: deregulation 1215 hsa-mir-212 Autistic Disorder 18563458 miR-212: deregulation 1216 hsa-mir-23a Autistic Disorder 18563458 miR-23a: deregulation 1217 hsa-mir-23a Autistic Disorder 19360674 miR-23a: upregulated 1218 hsa-mir-23b Autistic Disorder 19360674 miR-23b: upregulated 1219 hsa-mir-27a Autistic Disorder 18563458 miR-27a: deregulation 1220 hsa-mir-363 Autistic Disorder 19360674 miR-363: downregulated 1221 hsa-mir-381 Autistic Disorder 18563458 miR-381: deregulation 1222 hsa-mir-431 Autistic Disorder 18563458 miR-431: deregulation 1223 hsa-mir-432 Autistic Disorder 18563458 miR-432: deregulation 1224 hsa-mir-484 Autistic Disorder 18563458 miR-484: deregulation 1225 hsa-mir-539 Autistic Disorder 18563458 miR-539: deregulation 1226 hsa-mir-550a-1 Autistic Disorder 18563458 miR-550: deregulation 1227 hsa-mir-550a-2 Autistic Disorder 18563458 miR-550: deregulation 1228 hsa-mir-598 Autistic Disorder 18563458 miR-598: deregulation 1229 hsa-mir-652 Autistic Disorder 18563458 miR-652: deregulation 1230 hsa-mir-663a Autistic Disorder 19360674 miR-663: upregulated 1231 hsa-mir-7-1 Autistic Disorder 18563458 miR-7: deregulation 1232 hsa-mir-7-2 Autistic Disorder 18563458 miR-7: deregulation 1233 hsa-mir-7-3 Autistic Disorder 18563458 miR-7: deregulation 1234 hsa-mir-92a-1 Autistic Disorder 19360674 miR-92a-1: downregulated 1235 hsa-mir-92a-2 Autistic Disorder 19360674 miR-92a-2: downregulated 1236 hsa-mir-93 Autistic Disorder 18563458 miR-93: deregulation 1237 hsa-mir-95 Autistic Disorder 18563458 miR-95: deregulation 1238 hsa-mir-143 Barrett Esophagus 19190970 miR-143: significantly higher 1239 hsa-mir-196a-1 Barrett Esophagus 19342367 miR-196a: Marker of Progression 1240 hsa-mir-196a-2 Barrett Esophagus 19342367 miR-196a: Marker of Progression 1241 hsa-mir-17 Lymphoma, B-Cell 18941111 miR-17: down-regulates expression of distinct targets 1242 hsa-mir-18a Lymphoma, B-Cell 18941111 miR-18a: down-regulates expression of distinct targets 1243 hsa-mir-19a Lymphoma, B-Cell 18941111 miR-19a: down-regulates expression of distinct targets 1244 hsa-mir-19b-1 Lymphoma, B-Cell 18941111 miR-19b: down-regulates expression of distinct targets 1245 hsa-mir-19b-2 Lymphoma, B-Cell 18941111 miR-19b: down-regulates expression of distinct targets 1246 hsa-mir-20a Lymphoma, B-Cell 18941111 miR-20a: down-regulates expression of distinct targets 1247 hsa-mir-92a-1 Lymphoma, B-Cell 18941111 miR-92a: down-regulates expression of distinct targets 1248 hsa-mir-92a-2 Lymphoma, B-Cell 18941111 miR-92a: down-regulates expression of distinct targets 1249 hsa-mir-143 Urinary Bladder Neoplasms 19157460 miR-143: a tumor suppressor 1250 hsa-mir-101-1 Urinary Bladder Neoplasms 19258506 miR-101: putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2 1251 hsa-mir-101-2 Urinary Bladder Neoplasms 19258506 miR-101: putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2 1252 hsa-mir-205 Urinary Bladder Neoplasms 18799331 miR-205: miR-21/miR-205 expression ratio that has the ability to distinguish between invasive and noninvasive bladder tumors 1253 hsa-mir-21 Urinary Bladder Neoplasms 18799331 miR-21: miR-21/miR-205 expression ratio that has the ability to distinguish between invasive and noninvasive bladder tumors 1254 hsa-mir-222 Brain Neoplasms 19351827 miR-222: Overexpression 1255 hsa-mir-9-1 Brain Neoplasms 18624795 miR-9: Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors 1256 hsa-mir-9-1 Brain Neoplasms 18624795 miR-9*: Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors 1257 hsa-mir-9-2 Brain Neoplasms 18624795 miR-9: Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors 1258 hsa-mir-9-2 Brain Neoplasms 18624795 miR-9*: Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors 1259 hsa-mir-92b Brain Neoplasms 18624795 miR-92b: Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors 1260 hsa-mir-9-3 Brain Neoplasms 18624795 miR-9: Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors 1261 hsa-mir-9-3 Brain Neoplasms 18624795 miR-9*: Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors 1262 hsa-mir-10a Breast Neoplasms 19232136 miR-10a: miR-10a inhibits transcriptional of Hoxd4 1263 hsa-mir-146a Breast Neoplasms 19190326 miR-146: Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis 1264 hsa-mir-146a Breast Neoplasms 18634034 miR-146: rs2910164 were associated with increased risk of breast cancer in Chinese women 1265 hsa-mir-146a Breast Neoplasms 18660546 miR-146a: A functional polymorphism (rs2910164) in the miR-146a gene and age of familial breast/ovarian cancer diagnosis 1266 hsa-mir-146b Breast Neoplasms 19190326 miR-146: Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis 1267 hsa-mir-146b Breast Neoplasms 18634034 miR-146: rs2910164 were associated with increased risk of breast cancer in Chinese women 1268 hsa-mir-149 Breast Neoplasms 18634034 miR-149: rs2292832 were associated with increased risk of breast cancer in Chinese women 1269 hsa-mir-17 Breast Neoplasms 19048628 miR-17: mutations 1270 hsa-mir-17 Breast Neoplasms 18695042 miR-17-5p: regulatory feedback loop: cyclin D1 induces miR-17-5p/miR-20a, miR-17/20 repress cyclin D1 1271 hsa-mir-196a-2 Breast Neoplasms 18634034 miR-196a-2: rs11614913 were associated with increased risk of breast cancer in Chinese women 1272 hsa-mir-204 Breast Neoplasms 18922924 miR-204: upregulated 1273 hsa-mir-205 Breast Neoplasms 19276373 miR-205: a new oncosuppressor regulates HER3 1274 hsa-mir-205 Breast Neoplasms 19238171 miR-205: Suppress cell growth and invasion by target ErbB3 and VEGF-A 1275 hsa-mir-206 Breast Neoplasms 18593897 miR-206: down-regulated in estrogen receptor alpha-positive human breast cancer 1276 hsa-mir-20a Breast Neoplasms 18695042 miR-20a: regulatory feedback loop: cyclin D1 induces miR-17-5p/miR-20a, miR-17/20 repress cyclin D1 1277 hsa-mir-21 Breast Neoplasms 19308091 miR-21: BMP-6 inhibits microRNA-21 expression in breast cancer through repressing deltaEF1 and AP-1 1278 hsa-mir-21 Breast Neoplasms 19264808 miR-21: Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells. 1279 hsa-mir-21 Breast Neoplasms 18932017 miR-21: High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-beta1 1280 hsa-mir-21 Breast Neoplasms 18812439 miR-21: miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis 1281 hsa-mir-21 Breast Neoplasms 19212625 miR-21: upregulated, The expression levels of miR-21 were correlated with PTEN and commonly used clinicopathologic features of breast cancer 1282 hsa-mir-210 Breast Neoplasms 18755890 miR-210: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer 1283 hsa-mir-221 Breast Neoplasms 18708351 miR-221: MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1 1284 hsa-mir-221 Breast Neoplasms 18790736 miR-221: MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer 1285 hsa-mir-222 Breast Neoplasms 18708351 miR-222: MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1 1286 hsa-mir-222 Breast Neoplasms 18790736 miR-222: MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer 1287 hsa-mir-29a Breast Neoplasms 19247375 miR-29a: miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis. Therefore, miRNAs can act as either oncogenes or tumour suppressors, depending on the context 1288 hsa-mir-30c-1 Breast Neoplasms 19048628 miR-30c-1: mutations 1289 hsa-mir-451a Breast Neoplasms 18645025 miR-451: Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin 1290 hsa-mir-499a Breast Neoplasms 18634034 miR-499: rs3746444 were associated with increased risk of breast cancer in Chinese women 1291 hsa-mir-510 Breast Neoplasms 18922924 miR-510: upregulated 1292 hsa-mir-516a-1 Breast Neoplasms 18755890 miR-516-3p: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer 1293 hsa-mir-516a-2 Breast Neoplasms 18755890 miR-516-3p: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer 1294 hsa-mir-516b-1 Breast Neoplasms 18755890 miR-516-3p: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer 1295 hsa-mir-516b-2 Breast Neoplasms 18755890 miR-516-3p: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer 1296 hsa-mir-7-1 Breast Neoplasms 18755890 miR-7: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer 1297 hsa-mir-7-2 Breast Neoplasms 18755890 miR-7: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer 1298 hsa-mir-7-3 Breast Neoplasms 18755890 miR-7: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer 1299 hsa-let-7a-1 Neoplasms 18758960 Let-7a: Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3 1300 hsa-let-7a-1 Neoplasms 19211792 let-7a: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation 1301 hsa-let-7a-2 Neoplasms 18758960 Let-7a: Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3 1302 hsa-let-7a-2 Neoplasms 19211792 let-7a: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation 1303 hsa-let-7a-3 Neoplasms 18758960 Let-7a: Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3 1304 hsa-let-7a-3 Neoplasms 19211792 let-7a: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation 1305 hsa-let-7b Neoplasms 19211792 let-7b: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation 1306 hsa-let-7c Neoplasms 19211792 let-7c: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation 1307 hsa-let-7d Neoplasms 19211792 let-7d: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation 1308 hsa-let-7e Neoplasms 19211792 let-7e: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation 1309 hsa-let-7f-1 Neoplasms 19211792 let-7f: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation 1310 hsa-let-7f-2 Neoplasms 19211792 let-7f: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation 1311 hsa-let-7g Neoplasms 19211792 let-7g: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation 1312 hsa-let-7i Neoplasms 19211792 let-7i: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation 1313 hsa-mir-101-1 Neoplasms 19008416 miR-101: Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer 1314 hsa-mir-101-2 Neoplasms 19008416 miR-101: Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer 1315 hsa-mir-126 Neoplasms 19116145 miR-126: a tumor supressor: Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 1316 hsa-mir-141 Neoplasms 19182522 miR-141: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 1317 hsa-mir-145 Neoplasms 19202062 miR-145: putative tumor suppressor, miR-145 provides a direct link between p53 and c-Myc in this gene regulatory network 1318 hsa-mir-17 Neoplasms 18700987 miR-17-5p: The miR-17-5p microRNA is able to act as both an oncogene and a tumor suppressor in different cellular contexts 1319 hsa-mir-196b Neoplasms 18663355 miR-196: MicroRNA-196a targets annexin A1: a microRNA-mediated mechanism of annexin A1 downregulation in cancers 1320 hsa-mir-200a Neoplasms 19182522 miR-200a: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 1321 hsa-mir-200b Neoplasms 19182522 miR-200b: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 1322 hsa-mir-200c Neoplasms 19182522 miR-200c: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 1323 hsa-mir-21 Neoplasms 19073608 miR-21: coordinately regulate EGFR signaling in multiple human cancer cell types 1324 hsa-mir-27a Neoplasms 18619946 miR-27a: miR-27a and miR-451 regulate expression of MDR1/P-glycoprotein 1325 hsa-mir-34a Neoplasms 18719384 miR-34a: inactivation, Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer 1326 hsa-mir-34a Neoplasms 18834855 miR-34a: reduced or lost 1327 hsa-mir-429 Neoplasms 19182522 miR-429: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 1328 hsa-mir-451a Neoplasms 18619946 miR-451: miR-27a and miR-451 regulate expression of MDR1/P-glycoprotein 1329 hsa-mir-7-1 Neoplasms 19073608 miR-7: coordinately regulate EGFR signaling in multiple human cancer cell types 1330 hsa-mir-7-2 Neoplasms 19073608 miR-7: coordinately regulate EGFR signaling in multiple human cancer cell types 1331 hsa-mir-7-3 Neoplasms 19073608 miR-7: coordinately regulate EGFR signaling in multiple human cancer cell types 1332 hsa-mir-141 Carcinoma, Renal Cell 19228262 miR-141: down-regulated in malignant cancer than non-malignant one 1333 hsa-mir-155 Carcinoma, Renal Cell 19228262 miR-155: overexpressed in malignant cancer than non-malignant one 1334 hsa-mir-16-1 Carcinoma, Renal Cell 19228262 miR-16: overexpressed in malignant cancer than non-malignant one 1335 hsa-mir-16-2 Carcinoma, Renal Cell 19228262 miR-16: overexpressed in malignant cancer than non-malignant one 1336 hsa-mir-200b Carcinoma, Renal Cell 19228262 miR-200b: down-regulated in malignant cancer than non-malignant one 1337 hsa-mir-200c Carcinoma, Renal Cell 19228262 miR-200c: down-regulated in malignant cancer than non-malignant one 1338 hsa-mir-210 Carcinoma, Renal Cell 19228262 miR-210: overexpressed in malignant cancer than non-malignant one 1339 hsa-mir-224 Carcinoma, Renal Cell 19228262 miR-224: overexpressed in malignant cancer than non-malignant one 1340 hsa-mir-363 Carcinoma, Renal Cell 19228262 miR-363: down-regulated in malignant cancer than non-malignant one 1341 hsa-mir-429 Carcinoma, Renal Cell 19228262 miR-429: down-regulated in malignant cancer than non-malignant one 1342 hsa-mir-452 Carcinoma, Renal Cell 19228262 miR-452*: overexpressed in malignant cancer than non-malignant one 1343 hsa-mir-514a-1 Carcinoma, Renal Cell 19228262 miR-514: down-regulated in malignant cancer than non-malignant one 1344 hsa-mir-514a-2 Carcinoma, Renal Cell 19228262 miR-514: down-regulated in malignant cancer than non-malignant one 1345 hsa-mir-514a-3 Carcinoma, Renal Cell 19228262 miR-514: down-regulated in malignant cancer than non-malignant one 1346 hsa-mir-126 Uterine Cervical Neoplasms 18596939 miR-126: downregulated 1347 hsa-mir-143 Uterine Cervical Neoplasms 18596939 miR-143: downregulated 1348 hsa-mir-145 Uterine Cervical Neoplasms 18596939 miR-145: downregulated 1349 hsa-mir-146a Uterine Cervical Neoplasms 18596939 miR-146a: upregulated 1350 hsa-mir-155 Uterine Cervical Neoplasms 18596939 miR-155: upregulated 1351 hsa-mir-15b Uterine Cervical Neoplasms 18596939 miR-15b: upregulated 1352 hsa-mir-16-1 Uterine Cervical Neoplasms 18596939 miR-16: upregulated 1353 hsa-mir-16-2 Uterine Cervical Neoplasms 18596939 miR-16: upregulated 1354 hsa-mir-34a Uterine Cervical Neoplasms 19258450 miR-34a: Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6 1355 hsa-mir-142 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 19206004 miR-142-3p: up-regulated 1356 hsa-mir-222 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 19206004 miR-222: up-regulated 1357 hsa-mir-339 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 19206004 miR-339: up-regulated 1358 hsa-mir-373 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 19206004 miR-373*: down-regulated 1359 hsa-mir-451a Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 19206004 miR-451: down-regulated 1360 hsa-mir-22 Leukemia, Lymphocytic, Chronic, B-Cell 19144983 miR-22: downregulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification 1361 hsa-mir-29c Leukemia, Lymphocytic, Chronic, B-Cell 19144983 miR-29c: downregulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification 1362 hsa-mir-106b Leukemia, Lymphocytic, Chronic, B-Cell 19096009 miR-106b: Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase, Itch for degradation 1363 hsa-mir-10a Leukemia, Myeloid, Chronic-Phase 19074828 miR-10a: Down-regulation of hsa-miR-10a in chronic myeloid leukemia CD34+ cells increases USF2-mediated cell growth 1364 hsa-mir-21 Liver Cirrhosis 19203462 miR-21: n/a 1365 hsa-mir-92a-1 Leukemia, Lymphocytic, Chronic, B-Cell 19336759 miR-92-1: overexpressed, can target the VHL transcript 1366 hsa-mir-101-1 Colonic Neoplasms 19133256 miR-101: MiR-101 downregulation is involved in cyclooxygenase-2 overexpression 1367 hsa-mir-101-2 Colonic Neoplasms 19133256 miR-101: MiR-101 downregulation is involved in cyclooxygenase-2 overexpression 1368 hsa-mir-145 Colonic Neoplasms 18676867 miR-145: miR-145 potently suppressed growth of three different colon carcinoma cell lines 1369 hsa-mir-192 Colonic Neoplasms 19088023 miR-192: the effect of miR-192 on cellular proliferation is mainly p53 dependent 1370 hsa-mir-498 Colonic Neoplasms 18676867 miR-498: correlated with the probability of recurrence-free survival 1371 hsa-mir-126 Colonic Neoplasms 18663744 miR-126: miR-126 suppresses the growth of neoplastic cells 1372 hsa-mir-135a-1 Colorectal Neoplasms 18632633 miR-135a: miR-135 family: Regulation of the adenomatous polyposis coli gene 1373 hsa-mir-135a-2 Colorectal Neoplasms 18632633 miR-135a: miR-135 family: Regulation of the adenomatous polyposis coli gene 1374 hsa-mir-135b Colorectal Neoplasms 18632633 miR-135b: miR-135 family: Regulation of the adenomatous polyposis coli gene 1375 hsa-mir-143 Colorectal Neoplasms 19287964 miR-143: down-regualted 1376 hsa-mir-143 Colorectal Neoplasms 19242066 miR-143: only down-regulated in colon cancer but not in rectal cancer 1377 hsa-mir-145 Colorectal Neoplasms 19287964 miR-145: down-regulated 1378 hsa-mir-145 Colorectal Neoplasms 19242066 miR-145: down-regulated in both colon and rectal cancer 1379 hsa-mir-17 Colorectal Neoplasms 19201770 miR-17-3p: up-regulated both in plasma and tissue samples 1380 hsa-mir-17 Colorectal Neoplasms 19287964 miR-17-5p: up-regulated 1381 hsa-mir-183 Colorectal Neoplasms 19287964 miR-183: up-regulated 1382 hsa-mir-18a Colorectal Neoplasms 19287964 miR-18a: up-regulated 1383 hsa-mir-20a Colorectal Neoplasms 19287964 miR-20a: up-regulated 1384 hsa-mir-31 Colorectal Neoplasms 19287964 miR-31: up-regulated 1385 hsa-mir-31 Colorectal Neoplasms 19242066 miR-31: up-regulated compared with normal control 1386 hsa-mir-92b Colorectal Neoplasms 19287964 miR-92: up-regulated 1387 hsa-mir-221 Melanoma 19126397 miR-221: mir-221 can directly interact with c-kit 3'UTR and inhibit cKit protein translation 1388 hsa-mir-377 Diabetic Nephropathies 18716028 miR-377: MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy 1389 hsa-mir-145 Colorectal Neoplasms 19047896 miR-145: increased expression 1390 hsa-mir-181b-1 Colorectal Neoplasms 19047896 miR-181b: increased expression 1391 hsa-mir-203 Colorectal Neoplasms 19047896 miR-203: increased expression 1392 hsa-mir-20a Colorectal Neoplasms 19047896 miR-20a: increased expression 1393 hsa-mir-21 Colorectal Neoplasms 19047896 miR-21: increased expression 1394 hsa-mir-302b Carcinoma, Embryonal 18930031 miR-302b: "miR-302b maintains ""stemness"" of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression" 1395 hsa-mir-193b Adenocarcinoma 19077565 miR-193b: downregulated 1396 hsa-mir-204 Adenocarcinoma 19077565 miR-204: downregulated 1397 hsa-mir-205 Adenocarcinoma 19077565 miR-205: upregulated 1398 hsa-mir-429 Adenocarcinoma 19077565 miR-429: upregulated 1399 hsa-mir-449a Adenocarcinoma 19077565 miR-449: upregulated 1400 hsa-mir-449b Adenocarcinoma 19077565 miR-449: upregulated 1401 hsa-mir-99b Adenocarcinoma 19077565 miR-99b: downregulated 1402 hsa-mir-103a-1 Adenocarcinoma 19065659 miR-103: upregulated 1403 hsa-mir-103a-2 Adenocarcinoma 19065659 miR-103: upregulated 1404 hsa-mir-106a Adenocarcinoma 19065659 miR-106a: upregulated 1405 hsa-mir-151a Adenocarcinoma 19065659 miR-151: upregulated 1406 hsa-mir-155 Adenocarcinoma 19065659 miR-155: upregulated 1407 hsa-mir-182 Adenocarcinoma 19065659 miR-182: upregulated 1408 hsa-mir-183 Adenocarcinoma 19065659 miR-183: upregulated 1409 hsa-mir-194-1 Adenocarcinoma 19065659 miR-194: upregulated 1410 hsa-mir-194-2 Adenocarcinoma 19065659 miR-194: upregulated 1411 hsa-mir-200a Adenocarcinoma 19065659 miR-200a: upregulated 1412 hsa-mir-200c Adenocarcinoma 19065659 miR-200c: upregulated 1413 hsa-mir-203 Adenocarcinoma 19065659 miR-203: upregulated 1414 hsa-mir-205 Adenocarcinoma 19065659 miR-205: upregulated 1415 hsa-mir-210 Adenocarcinoma 19065659 miR-210: upregulated 1416 hsa-mir-223 Adenocarcinoma 19065659 miR-223: upregulated 1417 hsa-mir-95 Adenocarcinoma 19065659 miR-95: upregulated 1418 hsa-mir-100 Endometriosis 19074548 miR-100: upregulated 1419 hsa-mir-1-1 Endometriosis 19074548 miR-1: upregulated 1420 hsa-mir-1-2 Endometriosis 19074548 miR-1: upregulated 1421 hsa-mir-125a Endometriosis 19074548 miR-125a: upregulated 1422 hsa-mir-125b-1 Endometriosis 19074548 miR-125b: upregulated 1423 hsa-mir-125b-2 Endometriosis 19074548 miR-125b: upregulated 1424 hsa-mir-126 Endometriosis 19074548 miR-126: upregulated 1425 hsa-mir-141 Endometriosis 19074548 miR-141: downregulated 1426 hsa-mir-142 Endometriosis 19074548 miR-142-3p: downregulated 1427 hsa-mir-143 Endometriosis 19074548 miR-143: upregulated 1428 hsa-mir-145 Endometriosis 19074548 miR-145: upregulated 1429 hsa-mir-150 Endometriosis 19074548 miR-150: upregulated 1430 hsa-mir-194-1 Endometriosis 19074548 miR-194: upregulated 1431 hsa-mir-194-2 Endometriosis 19074548 miR-194: upregulated 1432 hsa-mir-196b Endometriosis 19074548 miR-196b: downregulated 1433 hsa-mir-200a Endometriosis 19074548 miR-200a: downregulated 1434 hsa-mir-200b Endometriosis 19074548 miR-200b: downregulated 1435 hsa-mir-20a Endometriosis 19074548 miR-20a: downregulated 1436 hsa-mir-223 Endometriosis 19074548 miR-223: upregulated 1437 hsa-mir-29c Endometriosis 19074548 miR-29c: upregulated 1438 hsa-mir-34c Endometriosis 19074548 miR-34c: downregulated 1439 hsa-mir-365a Endometriosis 19074548 miR-365: upregulated 1440 hsa-mir-365b Endometriosis 19074548 miR-365: upregulated 1441 hsa-mir-424 Endometriosis 19074548 miR-424: downregulated 1442 hsa-mir-99a Endometriosis 19074548 miR-99a: upregulated 1443 hsa-mir-99b Endometriosis 19074548 miR-99b: upregulated 1444 hsa-mir-21 Esophageal Neoplasms 19276261 miR-21: overexpressed compared with with matched normal epitheliums, regulates the proliferation and invasion 1445 hsa-mir-659 Dementia 18723524 miR-659: Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia 1446 hsa-mir-27a Stomach Neoplasms 18789835 miR-27a: MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin 1447 hsa-mir-106b Stomach Neoplasms 19153141 miR-106b: inhibite p21,p27, and p57 1448 hsa-mir-106b Stomach Neoplasms 19175831 miR-106b: overexpressed 1449 hsa-mir-129-1 Stomach Neoplasms 19148490 miR-129: downregulated in undifferentiated gastric cancer 1450 hsa-mir-129-2 Stomach Neoplasms 19148490 miR-129: downregulated in undifferentiated gastric cancer 1451 hsa-mir-133b Stomach Neoplasms 19175831 miR-133b: down-regulated 1452 hsa-mir-139 Stomach Neoplasms 19175831 miR-139-5p: down-regulated 1453 hsa-mir-141 Stomach Neoplasms 19363643 miR-141: significantly down-regulated in gastric cancer 1454 hsa-mir-148a Stomach Neoplasms 19148490 miR-148: downregulated in undifferentiated gastric cancer 1455 hsa-mir-148b Stomach Neoplasms 19148490 miR-148: downregulated in undifferentiated gastric cancer 1456 hsa-mir-150 Stomach Neoplasms 19148490 miR-150: patients with high expression levels have lower survival time 1457 hsa-mir-17 Stomach Neoplasms 19175831 miR-17: overexpressed 1458 hsa-mir-18a Stomach Neoplasms 19175831 miR-18a: overexpressed 1459 hsa-mir-18b Stomach Neoplasms 19175831 miR-18b: overexpressed 1460 hsa-mir-195 Stomach Neoplasms 19175831 miR-195: down-regulated 1461 hsa-mir-19a Stomach Neoplasms 19175831 miR-19a: overexpressed 1462 hsa-mir-20a Stomach Neoplasms 19175831 miR-20a: overexpressed 1463 hsa-mir-20b Stomach Neoplasms 19175831 miR-20b: overexpressed 1464 hsa-mir-20b Stomach Neoplasms 19148490 miR-20b: patients with high expression levels have lower survival time 1465 hsa-mir-21 Stomach Neoplasms 18794849 miR-21: miR-21 plays a pivotal role in gastric cancer pathogenesis and progression 1466 hsa-mir-21 Stomach Neoplasms 19175831 miR-21: overexpressed 1467 hsa-mir-221 Stomach Neoplasms 19153141 miR-221: inhibite p21,p27, and p57 1468 hsa-mir-222 Stomach Neoplasms 19153141 miR-222: inhibite p21,p27, and p57 1469 hsa-mir-25 Stomach Neoplasms 19153141 miR-25: inhibite p21,p27, and p57 1470 hsa-mir-27a Stomach Neoplasms 19148490 miR-27a: There was a correlation between mir-27a and lymph node metastasis 1471 hsa-mir-31 Stomach Neoplasms 19175831 miR-31: down-regulated 1472 hsa-mir-340 Stomach Neoplasms 19175831 miR-340*: overexpressed 1473 hsa-mir-34a Stomach Neoplasms 18803879 miR-34: tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres 1474 hsa-mir-34b Stomach Neoplasms 18803879 miR-34: tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres 1475 hsa-mir-34b Stomach Neoplasms 19148490 miR-34b: upregulated in undifferentiated gastric cancer 1476 hsa-mir-34c Stomach Neoplasms 18803879 miR-34: tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres 1477 hsa-mir-34c Stomach Neoplasms 19148490 miR-34c: upregulated in undifferentiated gastric cancer 1478 hsa-mir-378a Stomach Neoplasms 19175831 miR-378: down-regulated 1479 hsa-mir-421 Stomach Neoplasms 19175831 miR-421: overexpressed 1480 hsa-mir-497 Stomach Neoplasms 19175831 miR-497: down-regulated 1481 hsa-mir-658 Stomach Neoplasms 19175831 miR-658: overexpressed 1482 hsa-mir-93 Stomach Neoplasms 19153141 miR-93: inhibite p21,p27, and p57 1483 hsa-mir-106a Stomach Neoplasms 18996190 miR-106a: oncogenic activity 1484 hsa-let-7a-1 Digestive System Neoplasms 19156147 let-7a: downregulation 1485 hsa-let-7a-2 Digestive System Neoplasms 19156147 let-7a: downregulation 1486 hsa-let-7a-3 Digestive System Neoplasms 19156147 let-7a: downregulation 1487 hsa-let-7b Digestive System Neoplasms 19156147 let-7b: downregulation 1488 hsa-let-7c Digestive System Neoplasms 19156147 let-7c: downregulation 1489 hsa-let-7d Digestive System Neoplasms 19156147 let-7d: downregulation 1490 hsa-let-7e Digestive System Neoplasms 19156147 let-7e: downregulation 1491 hsa-let-7f-1 Digestive System Neoplasms 19156147 let-7f: downregulation 1492 hsa-let-7f-2 Digestive System Neoplasms 19156147 let-7f: downregulation 1493 hsa-let-7g Digestive System Neoplasms 19156147 let-7g: downregulation 1494 hsa-let-7i Digestive System Neoplasms 19156147 let-7i: downregulation 1495 hsa-mir-451a Gastrointestinal Neoplasms 19318487 miR-451: microRNA-451 Regulates Macrophage Migration Inhibitory Factor Proliferation of Gastrointestinal Cancer Cells Production 1496 hsa-mir-124-1 Glioblastoma 18577219 miR-124: miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells 1497 hsa-mir-124-2 Glioblastoma 18577219 miR-124: miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells 1498 hsa-mir-124-3 Glioblastoma 18577219 miR-124: miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells 1499 hsa-mir-137 Glioblastoma 18577219 miR-137: miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells 1500 hsa-mir-21 Glioblastoma 19013014 miR-21: MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G 1501 hsa-mir-21 Glioblastoma 18829576 miR-21: MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma 1502 hsa-mir-451a Glioblastoma 18765229 miR-451: MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells 1503 hsa-mir-146b Glioma 19265686 miR-146b: microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs 1504 hsa-mir-15b Glioma 19135980 miR-15b: MicroRNA-15b regulates cell cycle progression by targeting cyclins 1505 hsa-mir-181a-1 Glioma 18710654 miR-181a: mir suppressor 1506 hsa-mir-181a-2 Glioma 18710654 miR-181a: mir suppressor 1507 hsa-mir-181b-1 Glioma 18710654 miR-181b: mir suppressor 1508 hsa-mir-181b-2 Glioma 18710654 miR-181b: mir suppressor 1509 hsa-mir-21 Glioma 18591254 miR-21: MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators 1510 hsa-mir-21 Cardiomyopathy, Hypertrophic 19336275 miR-21: miR-21 can protect this by targeting PDCD4 1511 hsa-mir-21 Heart Failure 19336275 miR-21: miR-21 can protect this by targeting PDCD4 1512 hsa-mir-21 Myocardial Infarction 19336275 miR-21: miR-21 can protect this by targeting PDCD4 1513 hsa-mir-21 Myocardial Ischemia 19336275 miR-21: miR-21 can protect this by targeting PDCD4 1514 hsa-mir-21 Myocardial Reperfusion Injury 19336275 miR-21: miR-21 can protect this by targeting PDCD4 1515 hsa-let-7a-1 Head and Neck Neoplasms 18798260 let-7a: overexpressed 1516 hsa-let-7a-2 Head and Neck Neoplasms 18798260 let-7a: overexpressed 1517 hsa-let-7a-3 Head and Neck Neoplasms 18798260 let-7a: overexpressed 1518 hsa-let-7b Head and Neck Neoplasms 18798260 let-7b: overexpressed 1519 hsa-let-7c Head and Neck Neoplasms 18798260 let-7c: overexpressed 1520 hsa-let-7d Head and Neck Neoplasms 18798260 let-7d: overexpressed 1521 hsa-let-7d Head and Neck Neoplasms 19179615 let-7d: show lower expression levels relative to normal adjacent tissue 1522 hsa-let-7e Head and Neck Neoplasms 18798260 let-7e: overexpressed 1523 hsa-let-7f-1 Head and Neck Neoplasms 18798260 let-7f: overexpressed 1524 hsa-let-7f-2 Head and Neck Neoplasms 18798260 let-7f: overexpressed 1525 hsa-let-7g Head and Neck Neoplasms 18798260 let-7g: overexpressed 1526 hsa-let-7i Head and Neck Neoplasms 18798260 let-7i: overexpressed 1527 hsa-mir-1-1 Head and Neck Neoplasms 19179615 miR-1: show lower expression levels relative to normal adjacent tissue 1528 hsa-mir-1-2 Head and Neck Neoplasms 19179615 miR-1: show lower expression levels relative to normal adjacent tissue 1529 hsa-mir-130b Head and Neck Neoplasms 19351747 miR-130b: up-regulated 1530 hsa-mir-133a-1 Head and Neck Neoplasms 19179615 miR-133a: show lower expression levels relative to normal adjacent tissue 1531 hsa-mir-133a-2 Head and Neck Neoplasms 19179615 miR-133a: show lower expression levels relative to normal adjacent tissue 1532 hsa-mir-142 Head and Neck Neoplasms 18798260 miR-142-3p: overexpressed 1533 hsa-mir-146b Head and Neck Neoplasms 18798260 miR-146b: overexpressed 1534 hsa-mir-155 Head and Neck Neoplasms 18798260 miR-155: overexpressed 1535 hsa-mir-181a-1 Head and Neck Neoplasms 19351747 miR-181a: up-regulated 1536 hsa-mir-181a-2 Head and Neck Neoplasms 19351747 miR-181a: up-regulated 1537 hsa-mir-181b-1 Head and Neck Neoplasms 19351747 miR-181b: up-regulated 1538 hsa-mir-181b-2 Head and Neck Neoplasms 19351747 miR-181b: up-regulated 1539 hsa-mir-181d Head and Neck Neoplasms 19351747 miR-181d: up-regulated 1540 hsa-mir-18a Head and Neck Neoplasms 18798260 miR-18: overexpressed 1541 hsa-mir-18a Head and Neck Neoplasms 19351747 miR-18a: up-regulated 1542 hsa-mir-18b Head and Neck Neoplasms 18798260 miR-18: overexpressed 1543 hsa-mir-193b Head and Neck Neoplasms 19351747 miR-193b: up-regulated 1544 hsa-mir-205 Head and Neck Neoplasms 19043531 mir-205: a marker of metastatic 1545 hsa-mir-205 Head and Neck Neoplasms 19179615 miR-205: show lower expression levels relative to normal adjacent tissue 1546 hsa-mir-21 Head and Neck Neoplasms 19179615 miR-21: is frequently overexpressed in human HNSCC 1547 hsa-mir-21 Head and Neck Neoplasms 18798260 miR-21: overexpressed 1548 hsa-mir-21 Head and Neck Neoplasms 19351747 miR-21: up-regulated 1549 hsa-mir-221 Head and Neck Neoplasms 19351747 miR-221: up-regulated 1550 hsa-mir-29c Head and Neck Neoplasms 18798260 miR-29c: overexpressed 1551 hsa-mir-455 Head and Neck Neoplasms 19351747 miR-455: up-regulated 1552 hsa-mir-491 Head and Neck Neoplasms 19351747 miR-491: up-regulated 1553 hsa-mir-499a Head and Neck Neoplasms 18798260 miR-499: underexpressed 1554 hsa-mir-15a Head and Neck Neoplasms 19117988 miR-15a: feed-forward loop: PKCalpha down-regulates miR-15a, which directly inhibits protein synthesis of cyclin E 1555 hsa-mir-1-1 Heart Failure 19059107 miR-1: decreased expression 1556 hsa-mir-1-2 Heart Failure 19059107 miR-1: decreased expression 1557 hsa-mir-133a-1 Heart Failure 19059107 miR-133a: decreased expression 1558 hsa-mir-133a-2 Heart Failure 19059107 miR-133a: decreased expression 1559 hsa-mir-133b Heart Failure 19059107 miR-133b: decreased expression 1560 hsa-mir-223 Reperfusion Injury 19104939 miR-223: miR-223 expression levels were greatly up-regulated in the livers after 75 min ischemia followed by 120 min reperfusion when compared to sham controls 1561 hsa-mir-146a Hepatitis B 19187610 miR-146a: up-regulated 1562 hsa-mir-15a Hepatitis B 19187610 miR-15a: down-regulated 1563 hsa-mir-181a-1 Hepatitis B 19187610 miR-181a: up-regulated 1564 hsa-mir-181a-2 Hepatitis B 19187610 miR-181a: up-regulated 1565 hsa-mir-181b-1 Hepatitis B 19187610 miR-181b: up-regulated 1566 hsa-mir-181b-2 Hepatitis B 19187610 miR-181b: up-regulated 1567 hsa-mir-200a Hepatitis B 19187610 miR-200: up-regulated 1568 hsa-mir-200b Hepatitis B 19187610 miR-200: up-regulated 1569 hsa-mir-200c Hepatitis B 19187610 miR-200: up-regulated 1570 hsa-mir-1-1 Hepatitis C 19360909 miR-1: down-regulated 1571 hsa-mir-1-2 Hepatitis C 19360909 miR-1: down-regulated 1572 hsa-mir-122 Hepatitis C 19122656 miR-122: Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy 1573 hsa-mir-122 Hepatitis C 18550664 miR-122: Liver-specific microRNA miR-122 enhances the replication of hepatitis C virus in nonhepatic cells 1574 hsa-mir-122 Hepatitis C 19020517 miR-122: microRNA-122 stimulates translation of hepatitis C virus RNA 1575 hsa-mir-196a-1 Hepatitis C 19360909 miR-196: down-regulated 1576 hsa-mir-196a-2 Hepatitis C 19360909 miR-196: down-regulated 1577 hsa-mir-196b Hepatitis C 19360909 miR-196: down-regulated 1578 hsa-mir-199a-1 Hepatitis C 19144437 miR-199a: Regulation of the hepatitis C virus genome replication 1579 hsa-mir-199a-2 Hepatitis C 19144437 miR-199a: Regulation of the hepatitis C virus genome replication 1580 hsa-mir-296 Hepatitis C 19360909 miR-296: down-regulated 1581 hsa-mir-30a Hepatitis C 19360909 miR-30: down-regulated 1582 hsa-mir-30b Hepatitis C 19360909 miR-30: down-regulated 1583 hsa-mir-30c-1 Hepatitis C 19360909 miR-30: down-regulated 1584 hsa-mir-30c-2 Hepatitis C 19360909 miR-30: down-regulated 1585 hsa-mir-30d Hepatitis C 19360909 miR-30: down-regulated 1586 hsa-mir-431 Hepatitis C 19360909 miR-431: down-regulated 1587 hsa-mir-448 Hepatitis C 19360909 miR-448: down-regulated 1588 hsa-mir-127 Carcinoma, Hepatocellular 18942116 miR-127: Down-regulation during hepatocarcinogenesis induced by a methyl-deficient diet 1589 hsa-mir-200b Carcinoma, Hepatocellular 18942116 miR-200b: Down-regulation during hepatocarcinogenesis induced by a methyl-deficient diet 1590 hsa-mir-34a Carcinoma, Hepatocellular 18942116 miR-34a: Down-regulation during hepatocarcinogenesis induced by a methyl-deficient diet 1591 hsa-mir-1-1 Carcinoma, Hepatocellular 18593903 miR-1: silenced 1592 hsa-mir-1-2 Carcinoma, Hepatocellular 18593903 miR-1: silenced 1593 hsa-mir-101-1 Carcinoma, Hepatocellular 19155302 miR-101: a tumor suppressor 1594 hsa-mir-101-1 Carcinoma, Hepatocellular 19133651 miR-101: MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene 1595 hsa-mir-101-2 Carcinoma, Hepatocellular 19155302 miR-101: a tumor suppressor 1596 hsa-mir-101-2 Carcinoma, Hepatocellular 19133651 miR-101: MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene 1597 hsa-mir-122 Carcinoma, Hepatocellular 19296470 miR-122: a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma 1598 hsa-mir-122 Carcinoma, Hepatocellular 18692484 miR-122: miR-122 targets an anti-apoptotic gene, Bcl-w, in human hepatocellular carcinoma cell lines 1599 hsa-mir-125b-1 Carcinoma, Hepatocellular 18649363 miR-125b: overexpression of miR-125b in HCC cell line could obviously suppress the cell growth and phosporylation of Akt 1600 hsa-mir-125b-2 Carcinoma, Hepatocellular 18649363 miR-125b: overexpression of miR-125b in HCC cell line could obviously suppress the cell growth and phosporylation of Akt 1601 hsa-mir-146a Carcinoma, Hepatocellular 18711148 miR-146a: A functional polymorphism (rs2910164) in the miR-146a gene is associated with the risk for hepatocellular carcinoma 1602 hsa-mir-17 Carcinoma, Hepatocellular 18688024 miR-17: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype 1603 hsa-mir-18a Carcinoma, Hepatocellular 19203451 miR-18: target BTG2 1604 hsa-mir-18a Carcinoma, Hepatocellular 18688024 miR-18a: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype 1605 hsa-mir-18a Carcinoma, Hepatocellular 19027010 miR-18a: prevents estrogen receptor-alpha expression, promoting proliferation 1606 hsa-mir-18b Carcinoma, Hepatocellular 19203451 miR-18: target BTG2 1607 hsa-mir-19a Carcinoma, Hepatocellular 18688024 miR-19a: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype 1608 hsa-mir-19b-1 Carcinoma, Hepatocellular 18688024 miR-19b: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype 1609 hsa-mir-19b-2 Carcinoma, Hepatocellular 18688024 miR-19b: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype 1610 hsa-mir-20a Carcinoma, Hepatocellular 18688024 miR-20a: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype 1611 hsa-mir-21 Carcinoma, Hepatocellular 18688024 miR-21: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype 1612 hsa-mir-223 Carcinoma, Hepatocellular 18555017 miR-223: MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1 1613 hsa-mir-34a Carcinoma, Hepatocellular 19006648 miR-34a: miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells 1614 hsa-mir-92a-1 Carcinoma, Hepatocellular 18688024 miR-92a: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype 1615 hsa-mir-92a-2 Carcinoma, Hepatocellular 18688024 miR-92a: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype 1616 hsa-mir-221 Hyperglycemia 19351599 miR-221: induced expression 1617 hsa-mir-155 Hodgkin Disease 19177201 miR-155: overexpressed 1618 hsa-mir-16-1 Hodgkin Disease 19177201 miR-16: overexpressed 1619 hsa-mir-16-2 Hodgkin Disease 19177201 miR-16: overexpressed 1620 hsa-mir-17 Hodgkin Disease 19177201 miR-17: overexpressed 1621 hsa-mir-18a Hodgkin Disease 19177201 miR-18a: overexpressed 1622 hsa-mir-19a Hodgkin Disease 19177201 miR-19a: overexpressed 1623 hsa-mir-19b-1 Hodgkin Disease 19177201 miR-19b: overexpressed 1624 hsa-mir-19b-2 Hodgkin Disease 19177201 miR-19b: overexpressed 1625 hsa-mir-20a Hodgkin Disease 19177201 miR-20a: overexpressed 1626 hsa-mir-21 Hodgkin Disease 19177201 miR-21: overexpressed 1627 hsa-mir-24-1 Hodgkin Disease 19177201 miR-24: overexpressed 1628 hsa-mir-24-2 Hodgkin Disease 19177201 miR-24: overexpressed 1629 hsa-mir-92a-1 Hodgkin Disease 19177201 miR-92a: overexpressed 1630 hsa-mir-92a-2 Hodgkin Disease 19177201 miR-92a: overexpressed 1631 hsa-let-7a-1 Hodgkin Disease 18583325 let-7a: overexpressed, down-regulation of PRDM1/Blimp-1 1632 hsa-let-7a-2 Hodgkin Disease 18583325 let-7a: overexpressed, down-regulation of PRDM1/Blimp-1 1633 hsa-let-7a-3 Hodgkin Disease 18583325 let-7a: overexpressed, down-regulation of PRDM1/Blimp-1 1634 hsa-mir-9-1 Hodgkin Disease 18583325 miR-9: overexpressed, down-regulation of PRDM1/Blimp-1 1635 hsa-mir-9-2 Hodgkin Disease 18583325 miR-9: overexpressed, down-regulation of PRDM1/Blimp-1 1636 hsa-mir-9-3 Hodgkin Disease 18583325 miR-9: overexpressed, down-regulation of PRDM1/Blimp-1 1637 hsa-let-7a-1 Neoplasms 19221491 let-7a: guardians against pluripotency and cancer progression 1638 hsa-let-7a-2 Neoplasms 19221491 let-7a: guardians against pluripotency and cancer progression 1639 hsa-let-7a-3 Neoplasms 19221491 let-7a: guardians against pluripotency and cancer progression 1640 hsa-let-7b Neoplasms 19221491 let-7b: guardians against pluripotency and cancer progression 1641 hsa-let-7c Neoplasms 19221491 let-7c: guardians against pluripotency and cancer progression 1642 hsa-let-7d Neoplasms 19221491 let-7d: guardians against pluripotency and cancer progression 1643 hsa-let-7e Neoplasms 19221491 let-7e: guardians against pluripotency and cancer progression 1644 hsa-let-7f-1 Neoplasms 19221491 let-7f: guardians against pluripotency and cancer progression 1645 hsa-let-7f-2 Neoplasms 19221491 let-7f: guardians against pluripotency and cancer progression 1646 hsa-let-7g Neoplasms 19221491 let-7g: guardians against pluripotency and cancer progression 1647 hsa-let-7i Neoplasms 19221491 let-7i: guardians against pluripotency and cancer progression 1648 hsa-mir-16-1 Neoplasms 19269153 miR-16: can be upregulated by Epigallocatechin gallate 1649 hsa-mir-16-2 Neoplasms 19269153 miR-16: can be upregulated by Epigallocatechin gallate 1650 hsa-mir-200a Neoplasms 19221491 miR-200: guardians against pluripotency and cancer progression 1651 hsa-mir-200b Neoplasms 19221491 miR-200: guardians against pluripotency and cancer progression 1652 hsa-mir-200c Neoplasms 19221491 miR-200: guardians against pluripotency and cancer progression 1653 hsa-mir-30e Neoplasms 19223510 miR-30e: directly targets Ubc9 1654 hsa-mir-21 Cholangiocarcinoma 19296468 miR-21: overexpressed 1655 hsa-let-7i Ovarian Neoplasms 19074899 let-7i: a novel biomarker and therapeutic target 1656 hsa-mir-100 Carcinoma, Hepatocellular 19360909 miR-100: overexpressed In HCC patients with hepatitis C and liver cirrhosis 1657 hsa-mir-106a Carcinoma, Hepatocellular 19360909 miR-106a: involve 1658 hsa-mir-106a Carcinoma, Hepatocellular 19360909 miR-106a: up-regulated in HCC compared to benign hepatocellular tumors 1659 hsa-mir-10a Carcinoma, Hepatocellular 19360909 miR-10a: overexpressed In HCC patients with hepatitis C and liver cirrhosis 1660 hsa-mir-122 Carcinoma, Hepatocellular 19360909 miR-122: be decreased in HCC compared to non-tumoral tissue 1661 hsa-mir-122 Carcinoma, Hepatocellular 19360909 miR-122: overexpressed In HCC patients with hepatitis C and liver cirrhosis 1662 hsa-mir-145 Carcinoma, Hepatocellular 19360909 miR-145: be decreased in HCC compared to non-tumoral tissue 1663 hsa-mir-145 Carcinoma, Hepatocellular 19360909 miR-145: up to five-fold down-regulated in hepatic tumors compared to normal liver parenchyma 1664 hsa-mir-17 Carcinoma, Hepatocellular 19360909 miR-17-5p: involve 1665 hsa-mir-198 Carcinoma, Hepatocellular 19360909 miR-198: up to five-fold down-regulated in hepatic tumors compared to normal liver parenchyma 1666 hsa-mir-199a-1 Carcinoma, Hepatocellular 19360909 miR-199a: be decreased in HCC compared to non-tumoral tissue 1667 hsa-mir-199a-2 Carcinoma, Hepatocellular 19360909 miR-199a: be decreased in HCC compared to non-tumoral tissue 1668 hsa-mir-203 Carcinoma, Hepatocellular 19360909 miR-203: up-regulated in HCC compared to benign hepatocellular tumors 1669 hsa-mir-20a Carcinoma, Hepatocellular 19360909 miR-20: involve 1670 hsa-mir-20b Carcinoma, Hepatocellular 19360909 miR-20: involve 1671 hsa-mir-21 Carcinoma, Hepatocellular 19360909 miR-21: up-regulated in HCC compared to benign hepatocellular tumors 1672 hsa-mir-221 Carcinoma, Hepatocellular 19360909 miR-221: up-regulated in HCC compared to benign hepatocellular tumors 1673 hsa-mir-222 Carcinoma, Hepatocellular 19360909 miR-222: up-regulated in HCC compared to benign hepatocellular tumors 1674 hsa-mir-224 Carcinoma, Hepatocellular 19360909 miR-224: up-regulated in HCC compared to benign hepatocellular tumors 1675 hsa-mir-34a Carcinoma, Hepatocellular 19360909 miR-34a: up-regulated in HCC compared to benign hepatocellular tumors 1676 hsa-mir-92a-1 Carcinoma, Hepatocellular 19360909 miR-92: involve 1677 hsa-mir-92a-2 Carcinoma, Hepatocellular 19360909 miR-92: involve 1678 hsa-mir-92b Carcinoma, Hepatocellular 19360909 miR-92: involve 1679 hsa-mir-17 Leukemia, Myeloid 19155294 miR-17: overexpressed 1680 hsa-mir-18a Leukemia, Myeloid 19155294 miR-18a: overexpressed 1681 hsa-mir-19a Leukemia, Myeloid 19155294 miR-19a: overexpressed 1682 hsa-mir-19b-1 Leukemia, Myeloid 19155294 miR-19b: overexpressed 1683 hsa-mir-19b-2 Leukemia, Myeloid 19155294 miR-19b: overexpressed 1684 hsa-mir-20a Leukemia, Myeloid 19155294 miR-20a: overexpressed 1685 hsa-mir-92a-1 Leukemia, Myeloid 19155294 miR-92a: overexpressed 1686 hsa-mir-92a-2 Leukemia, Myeloid 19155294 miR-92a: overexpressed 1687 hsa-mir-205 Prostatic Neoplasms 19244118 miR-205: miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon 1688 hsa-mir-1-1 Cardiomegaly 19188439 miR-1: MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes 1689 hsa-mir-1-2 Cardiomegaly 19188439 miR-1: MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes 1690 hsa-mir-21 Carcinoma, Ductal, Breast 19080492 miR-21: expression is significantly higher than the normal controls 1691 hsa-let-7a-1 Sarcoma, Kaposi 19252139 let-7a: down-regulated 1692 hsa-let-7a-2 Sarcoma, Kaposi 19252139 let-7a: down-regulated 1693 hsa-let-7a-3 Sarcoma, Kaposi 19252139 let-7a: down-regulated 1694 hsa-let-7b Sarcoma, Kaposi 19252139 let-7b: down-regulated 1695 hsa-let-7c Sarcoma, Kaposi 19252139 let-7c: down-regulated 1696 hsa-let-7d Sarcoma, Kaposi 19252139 let-7d: down-regulated 1697 hsa-let-7e Sarcoma, Kaposi 19252139 let-7e: down-regulated 1698 hsa-let-7f-1 Sarcoma, Kaposi 19252139 let-7f: down-regulated 1699 hsa-let-7f-2 Sarcoma, Kaposi 19252139 let-7f: down-regulated 1700 hsa-let-7g Sarcoma, Kaposi 19252139 let-7g: down-regulated 1701 hsa-let-7i Sarcoma, Kaposi 19252139 let-7i: down-regulated 1702 hsa-mir-221 Sarcoma, Kaposi 19252139 miR-221: down-regulated 1703 hsa-mir-222 Sarcoma, Kaposi 19252139 miR-222: down-regulated 1704 hsa-mir-98 Sarcoma, Kaposi 19252139 miR-98: down-regulated 1705 hsa-mir-125a Leukemia 19022373 miR-125a: upregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal 1706 hsa-mir-181a-1 Leukemia 19022373 miR-181a*: downregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal 1707 hsa-mir-181a-2 Leukemia 19022373 miR-181a*: downregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal 1708 hsa-mir-199b Leukemia 19022373 miR-199b: downregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal 1709 hsa-mir-339 Leukemia 19022373 miR-339: upregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal 1710 hsa-mir-378a Leukemia 19022373 miR-378: downregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal 1711 hsa-mir-454 Leukemia 19022373 miR-454-3p: downregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal 1712 hsa-mir-575 Leukemia 19022373 miR-575: downregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal 1713 hsa-mir-660 Leukemia 19022373 miR-660: upregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal 1714 hsa-mir-663a Leukemia 19022373 miR-663: upregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal 1715 hsa-let-7a-1 Lung Neoplasms 18922928 let-7a: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk 1716 hsa-let-7a-2 Lung Neoplasms 18922928 let-7a: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk 1717 hsa-let-7a-3 Lung Neoplasms 18922928 let-7a: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk 1718 hsa-let-7b Lung Neoplasms 18922928 let-7b: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk 1719 hsa-let-7c Lung Neoplasms 18922928 let-7c: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk 1720 hsa-let-7d Lung Neoplasms 18922928 let-7d: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk 1721 hsa-let-7e Lung Neoplasms 18922928 let-7e: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk 1722 hsa-let-7f-1 Lung Neoplasms 18922928 let-7f: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk 1723 hsa-let-7f-2 Lung Neoplasms 18922928 let-7f: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk 1724 hsa-let-7g Lung Neoplasms 18922928 let-7g: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk 1725 hsa-let-7i Lung Neoplasms 18922928 let-7i: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk 1726 hsa-mir-1-1 Lung Neoplasms 18818206 miR-1: Down-regulation 1727 hsa-mir-1-2 Lung Neoplasms 18818206 miR-1: Down-regulation 1728 hsa-mir-126 Lung Neoplasms 19223090 miR-126: inhibit the growth 1729 hsa-mir-183 Lung Neoplasms 18840437 miR-183: a potential metastasis-inhibitor 1730 hsa-mir-196a-2 Lung Neoplasms 19293314 miR-196a-2: Susceptibility of Lung Cancer in Chinese 1731 hsa-mir-126 Lung Neoplasms 18602365 miR-126: MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines 1732 hsa-mir-205 Lung Neoplasms 19273703 miR-205: hsa-miR-205 as a highly specific marker for squamous cell lung carcinoma 1733 hsa-let-7a-1 Lupus Vulgaris 18998140 let-7a: upregulation 1734 hsa-let-7a-2 Lupus Vulgaris 18998140 let-7a: upregulation 1735 hsa-let-7a-3 Lupus Vulgaris 18998140 let-7a: upregulation 1736 hsa-let-7e Lupus Vulgaris 18998140 let-7e: upregulation 1737 hsa-mir-130b Lupus Vulgaris 18998140 miR-130b: upregulation 1738 hsa-mir-134 Lupus Vulgaris 18998140 miR-134: upregulation 1739 hsa-mir-142 Lupus Vulgaris 18998140 miR-142-5p: upregulation 1740 hsa-mir-146a Lupus Vulgaris 19333922 miR-146a: miR-146a contributes to abnormal activation of the type i interferon pathway in human lupus by targeting the key signaling proteins 1741 hsa-mir-150 Lupus Vulgaris 18998140 miR-150: downregulation 1742 hsa-mir-184 Lupus Vulgaris 18998140 miR-184: upregulation 1743 hsa-mir-185 Lupus Vulgaris 18998140 miR-185: upregulation 1744 hsa-mir-195 Lupus Vulgaris 18998140 miR-195: upregulation 1745 hsa-mir-197 Lupus Vulgaris 18998140 miR-197: upregulation 1746 hsa-mir-198 Lupus Vulgaris 18998140 miR-198: upregulation 1747 hsa-mir-200c Lupus Vulgaris 18998140 miR-200c: upregulation 1748 hsa-mir-208b Lupus Vulgaris 18998140 miR-208: upregulation 1749 hsa-mir-210 Lupus Vulgaris 18998140 miR-210: downregulation 1750 hsa-mir-223 Lupus Vulgaris 18998140 miR-223: downregulation 1751 hsa-mir-23a Lupus Vulgaris 18998140 miR-23a: upregulation 1752 hsa-mir-296 Lupus Vulgaris 18998140 miR-296: downregulation 1753 hsa-mir-30a Lupus Vulgaris 18998140 miR-30a-5p: upregulation 1754 hsa-mir-30d Lupus Vulgaris 18998140 miR-30d: downregulation 1755 hsa-mir-324 Lupus Vulgaris 18998140 miR-324-3p: downregulation 1756 hsa-mir-324 Lupus Vulgaris 18998140 miR-324-5p: upregulation 1757 hsa-mir-346 Lupus Vulgaris 18998140 miR-346: downregulation 1758 hsa-mir-365a Lupus Vulgaris 18998140 miR-365: downregulation 1759 hsa-mir-365b Lupus Vulgaris 18998140 miR-365: downregulation 1760 hsa-mir-423 Lupus Vulgaris 18998140 miR-423: downregulation 1761 hsa-mir-433 Lupus Vulgaris 18998140 miR-433: upregulation 1762 hsa-mir-484 Lupus Vulgaris 18998140 miR-484: downregulation 1763 hsa-mir-486 Lupus Vulgaris 18998140 miR-486: downregulation 1764 hsa-mir-494 Lupus Vulgaris 18998140 miR-494: upregulation 1765 hsa-mir-500a Lupus Vulgaris 18998140 miR-500: downregulation 1766 hsa-mir-516a-1 Lupus Vulgaris 18998140 miR-516-5p: upregulation 1767 hsa-mir-516a-2 Lupus Vulgaris 18998140 miR-516-5p: upregulation 1768 hsa-mir-516b-1 Lupus Vulgaris 18998140 miR-516-5p: upregulation 1769 hsa-mir-516b-2 Lupus Vulgaris 18998140 miR-516-5p: upregulation 1770 hsa-mir-518b Lupus Vulgaris 18998140 miR-518b: downregulation 1771 hsa-mir-518c Lupus Vulgaris 18998140 miR-518c*: upregulation 1772 hsa-mir-557 Lupus Vulgaris 18998140 miR-557: downregulation 1773 hsa-mir-575 Lupus Vulgaris 18998140 miR-575: upregulation 1774 hsa-mir-583 Lupus Vulgaris 18998140 miR-583: upregulation 1775 hsa-mir-596 Lupus Vulgaris 18998140 miR-596: downregulation 1776 hsa-mir-600 Lupus Vulgaris 18998140 miR-600: upregulation 1777 hsa-mir-601 Lupus Vulgaris 18998140 miR-601: upregulation 1778 hsa-mir-602 Lupus Vulgaris 18998140 miR-602: downregulation 1779 hsa-mir-608 Lupus Vulgaris 18998140 miR-608: upregulation 1780 hsa-mir-611 Lupus Vulgaris 18998140 miR-611: downregulation 1781 hsa-mir-612 Lupus Vulgaris 18998140 miR-612: upregulation 1782 hsa-mir-615 Lupus Vulgaris 18998140 miR-615: downregulation 1783 hsa-mir-622 Lupus Vulgaris 18998140 miR-622: upregulation 1784 hsa-mir-629 Lupus Vulgaris 18998140 miR-629: downregulation 1785 hsa-mir-637 Lupus Vulgaris 18998140 miR-637: downregulation 1786 hsa-mir-638 Lupus Vulgaris 18998140 miR-638: upregulation 1787 hsa-mir-642a Lupus Vulgaris 18998140 miR-642: downregulation 1788 hsa-mir-654 Lupus Vulgaris 18998140 miR-654: downregulation 1789 hsa-mir-657 Lupus Vulgaris 18998140 miR-657: upregulation 1790 hsa-mir-658 Lupus Vulgaris 18998140 miR-658: upregulation 1791 hsa-mir-662 Lupus Vulgaris 18998140 miR-662: upregulation 1792 hsa-mir-663a Lupus Vulgaris 18998140 miR-663: downregulation 1793 hsa-mir-769 Lupus Vulgaris 18998140 miR-769-3p: downregulation 1794 hsa-mir-99a Lupus Vulgaris 18998140 miR-99a: downregulation 1795 hsa-mir-26a-1 Lymphoma 19197161 miR-26a: repressed by MYC 1796 hsa-mir-26a-2 Lymphoma 19197161 miR-26a: repressed by MYC 1797 hsa-let-7a-1 Melanoma 18679415 let-7a: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 1798 hsa-let-7a-2 Melanoma 18679415 let-7a: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 1799 hsa-let-7a-3 Melanoma 18679415 let-7a: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 1800 hsa-let-7b Melanoma 18679415 let-7b: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 1801 hsa-let-7c Melanoma 18679415 let-7c: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 1802 hsa-let-7d Melanoma 18679415 let-7d: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 1803 hsa-let-7e Melanoma 18679415 let-7e: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 1804 hsa-let-7f-1 Melanoma 18679415 let-7f: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 1805 hsa-let-7f-2 Melanoma 18679415 let-7f: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 1806 hsa-let-7g Melanoma 18679415 let-7g: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 1807 hsa-let-7i Melanoma 18679415 let-7i: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 1808 hsa-mir-20a Breast Neoplasms 18777135 miR-20a: increased expression in c-Myc induced mouse mammary tumors 1809 hsa-mir-20b Breast Neoplasms 18777135 miR-20b: increased expression in c-Myc induced mouse mammary tumors 1810 hsa-mir-222 Breast Neoplasms 18777135 miR-222: decreased expression in c-Myc induced mouse mammary tumors 1811 hsa-mir-9-1 Breast Neoplasms 18777135 miR-9: increased expression in c-Myc induced mouse mammary tumors 1812 hsa-mir-9-2 Breast Neoplasms 18777135 miR-9: increased expression in c-Myc induced mouse mammary tumors 1813 hsa-mir-9-3 Breast Neoplasms 18777135 miR-9: increased expression in c-Myc induced mouse mammary tumors 1814 hsa-mir-150 Marek Disease 19297609 miR-150: down-regulated 1815 hsa-mir-223 Marek Disease 19297609 miR-223: down-regulated 1816 hsa-mir-221 Marek Disease 19264608 miR-221: miR-221/222 target p27Kip1 in Marek's disease virus-transformed tumour cell line MSB-1 1817 hsa-mir-222 Marek Disease 19264608 miR-222: miR-221/222 target p27Kip1 in Marek's disease virus-transformed tumour cell line MSB-1 1818 hsa-mir-10b Medulloblastoma 18973228 miR-10b: different expression in tumors overexpression or not ErbB2 1819 hsa-mir-124-1 Medulloblastoma 18607543 miR-124: regulates cyclin dependent kinase 6 1820 hsa-mir-124-2 Medulloblastoma 18607543 miR-124: regulates cyclin dependent kinase 6 1821 hsa-mir-124-3 Medulloblastoma 18607543 miR-124: regulates cyclin dependent kinase 6 1822 hsa-mir-125a Medulloblastoma 18973228 miR-125a: promote growth arrest and apoptosis of MB cells 1823 hsa-mir-125b-1 Medulloblastoma 18973228 miR-125b: different expression in tumors overexpression or not ErbB2 1824 hsa-mir-125b-2 Medulloblastoma 18973228 miR-125b: different expression in tumors overexpression or not ErbB2 1825 hsa-mir-135a-1 Medulloblastoma 18973228 miR-135a: different expression in tumors overexpression or not ErbB2 1826 hsa-mir-135a-2 Medulloblastoma 18973228 miR-135a: different expression in tumors overexpression or not ErbB2 1827 hsa-mir-135b Medulloblastoma 18973228 miR-135b: different expression in tumors overexpression or not ErbB2 1828 hsa-mir-153-1 Medulloblastoma 18973228 miR-153: different expression in tumors overexpression or not ErbB2 1829 hsa-mir-153-1 Medulloblastoma 18973228 miR-153: downregulated in all MBs 1830 hsa-mir-153-2 Medulloblastoma 18973228 miR-153: different expression in tumors overexpression or not ErbB2 1831 hsa-mir-153-2 Medulloblastoma 18973228 miR-153: downregulated in all MBs 1832 hsa-mir-17 Medulloblastoma 19196975 miR-17: collaborates with the Sonic Hedgehog pathway 1833 hsa-mir-181b-1 Medulloblastoma 18973228 miR-181b: different expression in tumors overexpression or not c-Myc 1834 hsa-mir-181b-2 Medulloblastoma 18973228 miR-181b: different expression in tumors overexpression or not c-Myc 1835 hsa-mir-18a Medulloblastoma 19196975 miR-18a: collaborates with the Sonic Hedgehog pathway 1836 hsa-mir-199b Medulloblastoma 18973228 miR-199b: different expression in tumors overexpression or not ErbB2 1837 hsa-mir-199b Medulloblastoma 19308264 miR-199b-5p: MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma 1838 hsa-mir-19a Medulloblastoma 19196975 miR-19a: collaborates with the Sonic Hedgehog pathway 1839 hsa-mir-19b-1 Medulloblastoma 19196975 miR-19b: collaborates with the Sonic Hedgehog pathway 1840 hsa-mir-19b-2 Medulloblastoma 19196975 miR-19b: collaborates with the Sonic Hedgehog pathway 1841 hsa-mir-20a Medulloblastoma 19196975 miR-20a: collaborates with the Sonic Hedgehog pathway 1842 hsa-mir-31 Medulloblastoma 18973228 miR-31: downregulated in all MBs 1843 hsa-mir-9-1 Medulloblastoma 18973228 miR-9: promote growth arrest and apoptosis of MB cells 1844 hsa-mir-9-2 Medulloblastoma 18973228 miR-9: promote growth arrest and apoptosis of MB cells 1845 hsa-mir-92a-1 Medulloblastoma 19196975 miR-92a: collaborates with the Sonic Hedgehog pathway 1846 hsa-mir-92a-2 Medulloblastoma 19196975 miR-92a: collaborates with the Sonic Hedgehog pathway 1847 hsa-mir-9-3 Medulloblastoma 18973228 miR-9: promote growth arrest and apoptosis of MB cells 1848 hsa-mir-17 Medulloblastoma 19351822 miR-17: the most highly up-regulated miRNAs in medulloblastoma 1849 hsa-mir-18a Medulloblastoma 19351822 miR-18a: the most highly up-regulated miRNAs in medulloblastoma 1850 hsa-mir-19a Medulloblastoma 19351822 miR-19a: the most highly up-regulated miRNAs in medulloblastoma 1851 hsa-mir-19b-1 Medulloblastoma 19351822 miR-19b: the most highly up-regulated miRNAs in medulloblastoma 1852 hsa-mir-19b-2 Medulloblastoma 19351822 miR-19b: the most highly up-regulated miRNAs in medulloblastoma 1853 hsa-mir-20a Medulloblastoma 19351822 miR-20a: the most highly up-regulated miRNAs in medulloblastoma 1854 hsa-mir-92a-1 Medulloblastoma 19351822 miR-92a: the most highly up-regulated miRNAs in medulloblastoma 1855 hsa-mir-92a-2 Medulloblastoma 19351822 miR-92a: the most highly up-regulated miRNAs in medulloblastoma 1856 hsa-mir-182 Melanoma 19188590 miR-182: Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor 1857 hsa-mir-532 Melanoma 19336521 miR-532-5p: miR-532-5p is a regulatory factor of RUNX3, which is down-regulated during melanoma progression 1858 hsa-mir-196b Leukemia 19188669 miR-196b: MLL normally regulates expression of mir-196b 1859 hsa-mir-206 Muscular Dystrophies 18827405 miR-206: miR-206 high expression for muscle regeneration and maturation 1860 hsa-mir-125b-1 Myelodysplastic Syndromes 18936236 miR-125b-1: Myeloid cell differentiation arrest by miR-125b-1 1861 hsa-mir-335 Multiple Myeloma 18700954 miR-335: deregulation 1862 hsa-mir-342 Multiple Myeloma 18700954 miR-342: deregulation 1863 hsa-mir-561 Multiple Myeloma 18700954 miR-561: deregulation 1864 hsa-mir-10a Myeloproliferative Disorders 18773208 miR-10a: deregulation 1865 hsa-mir-126 Myeloproliferative Disorders 18773208 miR-126: deregulation 1866 hsa-mir-17 Myeloproliferative Disorders 18773208 miR-17-5p: deregulation 1867 hsa-mir-20a Myeloproliferative Disorders 18773208 miR-20a: deregulation 1868 hsa-mir-21 Cardiomyopathies 19043405 miR-21: MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts 1869 hsa-mir-1-1 Myocardial Infarction 19245789 miR-1: Upregulated expression in a rat model 1870 hsa-mir-1-2 Myocardial Infarction 19245789 miR-1: Upregulated expression in a rat model 1871 hsa-mir-206 Myocardial Infarction 19245789 miR-206: Upregulated expression in a rat model 1872 hsa-mir-21 Myocardial Infarction 19147588 miR-21: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue 1873 hsa-mir-221 Carotid Artery Diseases 19150885 miR-221: knockdown of miR-221 and miR-222 in rat carotid arteries suppressed VSMC proliferation in vivo and neointimal lesion formation after angioplasty. The results indicate that miR-221 and miR-222 are novel regulators for VSMC proliferation and neointimal hype 1874 hsa-mir-222 Carotid Artery Diseases 19150885 miR-222: knockdown of miR-221 and miR-222 in rat carotid arteries suppressed VSMC proliferation in vivo and neointimal lesion formation after angioplasty. The results indicate that miR-221 and miR-222 are novel regulators for VSMC proliferation and neointimal hype 1875 hsa-mir-219-1 Nervous System Diseases 19196972 miR-219: MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction 1876 hsa-mir-219-2 Nervous System Diseases 19196972 miR-219: MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction 1877 hsa-mir-17 Azoospermia 19210773 miR-17: deregulation 1878 hsa-mir-18a Azoospermia 19210773 miR-18a: deregulation 1879 hsa-mir-19a Azoospermia 19210773 miR-19a: deregulation 1880 hsa-mir-19b-1 Azoospermia 19210773 miR-19b: deregulation 1881 hsa-mir-19b-2 Azoospermia 19210773 miR-19b: deregulation 1882 hsa-mir-20a Azoospermia 19210773 miR-20a: deregulation 1883 hsa-mir-302a Azoospermia 19210773 miR-302a: deregulation 1884 hsa-mir-371a Azoospermia 19210773 mir-371: deregulation 1885 hsa-mir-372 Azoospermia 19210773 mir-372: deregulation 1886 hsa-mir-373 Azoospermia 19210773 mir-373: deregulation 1887 hsa-mir-383 Azoospermia 19210773 miR-383: deregulation 1888 hsa-mir-491 Azoospermia 19210773 miR-491-3p: deregulation 1889 hsa-mir-520d Azoospermia 19210773 miR-520d-3p: deregulation 1890 hsa-mir-92a-1 Azoospermia 19210773 miR-92a: deregulation 1891 hsa-mir-92a-2 Azoospermia 19210773 miR-92a: deregulation 1892 hsa-mir-205 Carcinoma, Non-Small-Cell Lung 18719201 miR-205: overexpression 1893 hsa-mir-21 Carcinoma, Non-Small-Cell Lung 18719201 miR-21: overexpression 1894 hsa-mir-96 Hearing Loss 19363479 miR-96: Mutations in the seed region 1895 hsa-mir-143 Obesity 18809385 miR-143: Up-regulated expression of microRNA-143 in association with obesity in adipose 1896 hsa-mir-211 Carcinoma, Squamous Cell 18946016 miR-211: Association between high miR-211 microRNA expression and the poor prognosis 1897 hsa-mir-146a Osteoarthritis 19333945 miR-146a: miR-146 is intensely expressed in low-grade OA cartilage and that its expression is induced by stimulation of IL-1beta 1898 hsa-let-7e Ovarian Neoplasms 18823650 let-7e: deregulated 1899 hsa-mir-125b-1 Ovarian Neoplasms 18823650 miR-125b: deregulated 1900 hsa-mir-125b-2 Ovarian Neoplasms 18823650 miR-125b: deregulated 1901 hsa-mir-126 Ovarian Neoplasms 18954897 miR-126: over-expressed 1902 hsa-mir-127 Ovarian Neoplasms 18954897 miR-127: under-expression 1903 hsa-mir-130a Ovarian Neoplasms 18823650 miR-130a: deregulated 1904 hsa-mir-146a Ovarian Neoplasms 18660546 miR-146a: A functional polymorphism (rs2910164) in the miR-146a gene and age of familial breast/ovarian cancer diagnosis 1905 hsa-mir-155 Ovarian Neoplasms 18954897 miR-155: under-expression 1906 hsa-mir-21 Ovarian Neoplasms 18954897 miR-21: over-expressed 1907 hsa-mir-29a Ovarian Neoplasms 18954897 miR-29a: over-expressed 1908 hsa-mir-30c-1 Ovarian Neoplasms 18823650 miR-30c: deregulated 1909 hsa-mir-30c-2 Ovarian Neoplasms 18823650 miR-30c: deregulated 1910 hsa-mir-335 Ovarian Neoplasms 18823650 miR-335: deregulated 1911 hsa-mir-92b Ovarian Neoplasms 18954897 miR-92: over-expressed 1912 hsa-mir-93 Ovarian Neoplasms 18954897 miR-93: over-expressed 1913 hsa-mir-99b Ovarian Neoplasms 18954897 miR-99b: under-expression 1914 hsa-mir-146a Diabetes Mellitus, Type 2 18633110 miR-146: deregulation 1915 hsa-let-7a-1 Pancreatic Neoplasms 19323605 Let-7a: inhibits in vitro cell proliferation but fails to alter tumor progression 1916 hsa-let-7a-2 Pancreatic Neoplasms 19323605 Let-7a: inhibits in vitro cell proliferation but fails to alter tumor progression 1917 hsa-let-7a-3 Pancreatic Neoplasms 19323605 Let-7a: inhibits in vitro cell proliferation but fails to alter tumor progression 1918 hsa-let-7b Pancreatic Neoplasms 19323605 Let-7b: inhibits in vitro cell proliferation but fails to alter tumor progression 1919 hsa-let-7c Pancreatic Neoplasms 19323605 Let-7c: inhibits in vitro cell proliferation but fails to alter tumor progression 1920 hsa-let-7d Pancreatic Neoplasms 19323605 Let-7d: inhibits in vitro cell proliferation but fails to alter tumor progression 1921 hsa-let-7e Pancreatic Neoplasms 19323605 Let-7e: inhibits in vitro cell proliferation but fails to alter tumor progression 1922 hsa-let-7f-1 Pancreatic Neoplasms 19323605 Let-7f: inhibits in vitro cell proliferation but fails to alter tumor progression 1923 hsa-let-7f-2 Pancreatic Neoplasms 19323605 Let-7f: inhibits in vitro cell proliferation but fails to alter tumor progression 1924 hsa-let-7g Pancreatic Neoplasms 19323605 Let-7g: inhibits in vitro cell proliferation but fails to alter tumor progression 1925 hsa-let-7i Pancreatic Neoplasms 19323605 Let-7i: inhibits in vitro cell proliferation but fails to alter tumor progression 1926 hsa-mir-15b Pancreatic Neoplasms 19030927 miR-15b: upregulated 1927 hsa-mir-186 Pancreatic Neoplasms 19030927 miR-186: upregulated 1928 hsa-mir-190a Pancreatic Neoplasms 19030927 miR-190: upregulated 1929 hsa-mir-196a-1 Pancreatic Neoplasms 19030927 miR-196a: upregulated 1930 hsa-mir-196a-2 Pancreatic Neoplasms 19030927 miR-196a: upregulated 1931 hsa-mir-200b Pancreatic Neoplasms 19030927 miR-200b: upregulated 1932 hsa-mir-21 Pancreatic Neoplasms 18642050 miR-21: MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survival 1933 hsa-mir-221 Pancreatic Neoplasms 19030927 miR-221: upregulated 1934 hsa-mir-222 Pancreatic Neoplasms 19030927 miR-222: upregulated 1935 hsa-mir-95 Pancreatic Neoplasms 19030927 miR-95: upregulated 1936 hsa-mir-155 Pancreatic Neoplasms 19106647 miR-155: miR-155 is a biomarker of early pancreatic neoplasia 1937 hsa-mir-196a-1 Pancreatic Neoplasms 18719196 miR-196a: biomarkers improved the ability to distinguish between healthy tissue, PDAC, and chronic pancreatitis 1938 hsa-mir-196a-2 Pancreatic Neoplasms 18719196 miR-196a: biomarkers improved the ability to distinguish between healthy tissue, PDAC, and chronic pancreatitis 1939 hsa-mir-217 Pancreatic Neoplasms 18719196 miR-217: biomarkers improved the ability to distinguish between healthy tissue, PDAC, and chronic pancreatitis 1940 hsa-mir-146b Thyroid Neoplasms 18587330 miR-146b: overexpressed 1941 hsa-mir-221 Thyroid Neoplasms 18587330 miR-221: overexpressed 1942 hsa-mir-222 Thyroid Neoplasms 18587330 miR-222: overexpressed 1943 hsa-mir-372 Neoplasms, Germ Cell and Embryonal 19057917 miR-372: highly up-regulated 1944 hsa-mir-373 Neoplasms, Germ Cell and Embryonal 19057917 miR-373: highly up-regulated 1945 hsa-mir-372 Cerebellar Neoplasms 19057917 miR-372: highly up-regulated 1946 hsa-mir-373 Cerebellar Neoplasms 19057917 miR-373: highly up-regulated 1947 hsa-let-7a-1 Pituitary Neoplasms 19136928 let-7a: Overexpression of HMGA2 relates to reduction of the let-7 1948 hsa-let-7a-2 Pituitary Neoplasms 19136928 let-7a: Overexpression of HMGA2 relates to reduction of the let-7 1949 hsa-let-7a-3 Pituitary Neoplasms 19136928 let-7a: Overexpression of HMGA2 relates to reduction of the let-7 1950 hsa-let-7b Pituitary Neoplasms 19136928 let-7b: Overexpression of HMGA2 relates to reduction of the let-7 1951 hsa-let-7c Pituitary Neoplasms 19136928 let-7c: Overexpression of HMGA2 relates to reduction of the let-7 1952 hsa-let-7d Pituitary Neoplasms 19136928 let-7d: Overexpression of HMGA2 relates to reduction of the let-7 1953 hsa-let-7e Pituitary Neoplasms 19136928 let-7e: Overexpression of HMGA2 relates to reduction of the let-7 1954 hsa-let-7f-1 Pituitary Neoplasms 19136928 let-7f: Overexpression of HMGA2 relates to reduction of the let-7 1955 hsa-let-7f-2 Pituitary Neoplasms 19136928 let-7f: Overexpression of HMGA2 relates to reduction of the let-7 1956 hsa-let-7g Pituitary Neoplasms 19136928 let-7g: Overexpression of HMGA2 relates to reduction of the let-7 1957 hsa-let-7i Pituitary Neoplasms 19136928 let-7i: Overexpression of HMGA2 relates to reduction of the let-7 1958 hsa-let-7a-1 Salivary Gland Neoplasms 19347935 let-7a: down-regulated 1959 hsa-let-7a-2 Salivary Gland Neoplasms 19347935 let-7a: down-regulated 1960 hsa-let-7a-3 Salivary Gland Neoplasms 19347935 let-7a: down-regulated 1961 hsa-mir-140 Salivary Gland Neoplasms 19347935 miR-140: up-regulated 1962 hsa-mir-140 Salivary Gland Neoplasms 19347935 miR-140-5p: up-regulated 1963 hsa-mir-144 Salivary Gland Neoplasms 19347935 miR-144: down-regulated 1964 hsa-mir-154 Salivary Gland Neoplasms 19347935 miR-154: up-regulated 1965 hsa-mir-188 Salivary Gland Neoplasms 19347935 miR-188: up-regulated 1966 hsa-mir-20b Salivary Gland Neoplasms 19347935 miR-20b: down-regulated 1967 hsa-mir-21 Salivary Gland Neoplasms 19347935 miR-21: up-regulated 1968 hsa-mir-23b Salivary Gland Neoplasms 19347935 miR-23b: up-regulated 1969 hsa-mir-299 Salivary Gland Neoplasms 19347935 miR-299-3p: up-regulated 1970 hsa-mir-29c Salivary Gland Neoplasms 19347935 miR-29c: up-regulated 1971 hsa-mir-301a Salivary Gland Neoplasms 19347935 miR-301: up-regulated 1972 hsa-mir-301b Salivary Gland Neoplasms 19347935 miR-301: up-regulated 1973 hsa-mir-302c Salivary Gland Neoplasms 19347935 miR-302c: up-regulated 1974 hsa-mir-337 Salivary Gland Neoplasms 19347935 miR-337: up-regulated 1975 hsa-mir-375 Salivary Gland Neoplasms 19347935 miR-375: down-regulated 1976 hsa-mir-376a-1 Salivary Gland Neoplasms 19347935 miR-376a: up-regulated 1977 hsa-mir-376a-2 Salivary Gland Neoplasms 19347935 miR-376a: up-regulated 1978 hsa-mir-409 Salivary Gland Neoplasms 19347935 miR-409-3p: up-regulated 1979 hsa-mir-449a Salivary Gland Neoplasms 19347935 miR-449: up-regulated 1980 hsa-mir-449b Salivary Gland Neoplasms 19347935 miR-449: up-regulated 1981 hsa-mir-495 Salivary Gland Neoplasms 19347935 miR-495: up-regulated 1982 hsa-mir-99b Salivary Gland Neoplasms 19347935 miR-99b: up-regulated 1983 hsa-mir-15a Polycystic Kidney Diseases 18949056 miR-15a: MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis 1984 hsa-mir-15a Liver Diseases 19360909 miR-15a: decreased 1985 hsa-mir-152 Pre-Eclampsia 19285651 miR-152: expressed differentially in preeclamptic placentas vs normal controls 1986 hsa-mir-210 Pre-Eclampsia 19285651 miR-210: expressed differentially in preeclamptic placentas vs normal controls 1987 hsa-mir-411 Pre-Eclampsia 19285651 miR-411: expressed differentially in preeclamptic placentas vs normal controls 1988 hsa-let-7a-1 Lymphoma, Primary Effusion 19252139 let-7a: down-regulated 1989 hsa-let-7a-2 Lymphoma, Primary Effusion 19252139 let-7a: down-regulated 1990 hsa-let-7a-3 Lymphoma, Primary Effusion 19252139 let-7a: down-regulated 1991 hsa-let-7b Lymphoma, Primary Effusion 19252139 let-7b: down-regulated 1992 hsa-let-7c Lymphoma, Primary Effusion 19252139 let-7c: down-regulated 1993 hsa-let-7d Lymphoma, Primary Effusion 19252139 let-7d: down-regulated 1994 hsa-let-7e Lymphoma, Primary Effusion 19252139 let-7e: down-regulated 1995 hsa-let-7f-1 Lymphoma, Primary Effusion 19252139 let-7f: down-regulated 1996 hsa-let-7f-2 Lymphoma, Primary Effusion 19252139 let-7f: down-regulated 1997 hsa-let-7g Lymphoma, Primary Effusion 19252139 let-7g: down-regulated 1998 hsa-let-7i Lymphoma, Primary Effusion 19252139 let-7i: down-regulated 1999 hsa-mir-221 Lymphoma, Primary Effusion 19252139 miR-221: down-regulated 2000 hsa-mir-222 Lymphoma, Primary Effusion 19252139 miR-222: down-regulated 2001 hsa-mir-98 Lymphoma, Primary Effusion 19252139 miR-98: down-regulated 2002 hsa-let-7a-1 Adrenocortical Carcinoma 19351815 let-7a: upregulated 2003 hsa-let-7a-2 Adrenocortical Carcinoma 19351815 let-7a: upregulated 2004 hsa-let-7a-3 Adrenocortical Carcinoma 19351815 let-7a: upregulated 2005 hsa-let-7b Adrenocortical Carcinoma 19351815 let-7b: upregulated 2006 hsa-let-7c Adrenocortical Carcinoma 19351815 let-7c: upregulated 2007 hsa-let-7d Adrenocortical Carcinoma 19351815 let-7d: upregulated 2008 hsa-mir-100 Adrenocortical Carcinoma 19351815 miR-100: upregulated 2009 hsa-mir-106b Adrenocortical Carcinoma 19351815 miR-106b: down-regulated 2010 hsa-mir-1-1 Adrenocortical Carcinoma 19351815 miR-1: upregulated 2011 hsa-mir-1-2 Adrenocortical Carcinoma 19351815 miR-1: upregulated 2012 hsa-mir-125b-1 Adrenocortical Carcinoma 19351815 miR-125b: upregulated 2013 hsa-mir-125b-2 Adrenocortical Carcinoma 19351815 miR-125b: upregulated 2014 hsa-mir-126 Adrenocortical Carcinoma 19351815 miR-126: upregulated 2015 hsa-mir-130a Adrenocortical Carcinoma 19351815 miR-130a: upregulated 2016 hsa-mir-132 Adrenocortical Carcinoma 19351815 miR-132: upregulated 2017 hsa-mir-133a-1 Adrenocortical Carcinoma 19351815 miR-133a: upregulated 2018 hsa-mir-133a-2 Adrenocortical Carcinoma 19351815 miR-133a: upregulated 2019 hsa-mir-135a-1 Adrenocortical Carcinoma 19351815 miR-135a: upregulated 2020 hsa-mir-135a-2 Adrenocortical Carcinoma 19351815 miR-135a: upregulated 2021 hsa-mir-137 Adrenocortical Carcinoma 19351815 miR-137: upregulated 2022 hsa-mir-139 Adrenocortical Carcinoma 19351815 miR-139: down-regulated 2023 hsa-mir-143 Adrenocortical Carcinoma 19351815 miR-143: upregulated 2024 hsa-mir-145 Adrenocortical Carcinoma 19351815 miR-145: upregulated 2025 hsa-mir-146a Adrenocortical Carcinoma 19351815 miR-146a: upregulated 2026 hsa-mir-148a Adrenocortical Carcinoma 19351815 miR-148a: down-regulated 2027 hsa-mir-155 Adrenocortical Carcinoma 19351815 miR-155: upregulated 2028 hsa-mir-15b Adrenocortical Carcinoma 19351815 miR-15b: upregulated 2029 hsa-mir-16-1 Adrenocortical Carcinoma 19351815 miR-16: upregulated 2030 hsa-mir-16-2 Adrenocortical Carcinoma 19351815 miR-16: upregulated 2031 hsa-mir-17 Adrenocortical Carcinoma 19351815 miR-17-5p: upregulated 2032 hsa-mir-192 Adrenocortical Carcinoma 19351815 miR-192: upregulated 2033 hsa-mir-194-1 Adrenocortical Carcinoma 19351815 miR-194: upregulated 2034 hsa-mir-194-2 Adrenocortical Carcinoma 19351815 miR-194: upregulated 2035 hsa-mir-196a-1 Adrenocortical Carcinoma 19351815 miR-196a: down-regulated 2036 hsa-mir-196a-2 Adrenocortical Carcinoma 19351815 miR-196a: down-regulated 2037 hsa-mir-200b Adrenocortical Carcinoma 19351815 miR-200b: upregulated 2038 hsa-mir-200c Adrenocortical Carcinoma 19351815 miR-200c: upregulated 2039 hsa-mir-203 Adrenocortical Carcinoma 19351815 miR-203: upregulated 2040 hsa-mir-210 Adrenocortical Carcinoma 19351815 miR-210: down-regulated 2041 hsa-mir-222 Adrenocortical Carcinoma 19351815 miR-222: upregulated 2042 hsa-mir-23b Adrenocortical Carcinoma 19351815 miR-23b: upregulated 2043 hsa-mir-28 Adrenocortical Carcinoma 19351815 miR-28: upregulated 2044 hsa-mir-301a Adrenocortical Carcinoma 19351815 miR-301: down-regulated 2045 hsa-mir-301b Adrenocortical Carcinoma 19351815 miR-301: down-regulated 2046 hsa-mir-30a Adrenocortical Carcinoma 19351815 miR-30a-3p: upregulated 2047 hsa-mir-335 Adrenocortical Carcinoma 19351815 miR-335: upregulated 2048 hsa-mir-375 Adrenocortical Carcinoma 19351815 miR-375: upregulated 2049 hsa-mir-376a-1 Adrenocortical Carcinoma 19351815 miR-376: down-regulated 2050 hsa-mir-376a-2 Adrenocortical Carcinoma 19351815 miR-376: down-regulated 2051 hsa-mir-376b Adrenocortical Carcinoma 19351815 miR-376: down-regulated 2052 hsa-mir-376c Adrenocortical Carcinoma 19351815 miR-376: down-regulated 2053 hsa-mir-424 Adrenocortical Carcinoma 19351815 miR-424: down-regulated 2054 hsa-mir-449a Adrenocortical Carcinoma 19351815 miR-449: upregulated 2055 hsa-mir-449b Adrenocortical Carcinoma 19351815 miR-449: upregulated 2056 hsa-mir-484 Adrenocortical Carcinoma 19351815 miR-484: down-regulated 2057 hsa-mir-491 Adrenocortical Carcinoma 19351815 miR-491: down-regulated 2058 hsa-mir-7-1 Adrenocortical Carcinoma 19351815 miR-7: upregulated 2059 hsa-mir-7-2 Adrenocortical Carcinoma 19351815 miR-7: upregulated 2060 hsa-mir-7-3 Adrenocortical Carcinoma 19351815 miR-7: upregulated 2061 hsa-let-7b Neurodegenerative Diseases 18987751 let-7b: up-regulated 2062 hsa-mir-139 Neurodegenerative Diseases 18987751 miR-139-5p: up-regulated 2063 hsa-mir-146a Neurodegenerative Diseases 18987751 miR-146a: up-regulated 2064 hsa-mir-328 Neurodegenerative Diseases 18987751 miR-328: up-regulated 2065 hsa-mir-337 Neurodegenerative Diseases 18987751 miR-337-3p: down-regulated 2066 hsa-mir-338 Neurodegenerative Diseases 18987751 miR-338-3p: down-regulated 2067 hsa-mir-342 Neurodegenerative Diseases 18987751 miR-342-3p: up-regulated 2068 hsa-mir-96 Hearing Loss 19363478 miR-96: An ENU-induced mutation 2069 hsa-mir-106b Prostatic Neoplasms 18676839 miR-106b: significantly higher expression 2070 hsa-mir-15a Prostatic Neoplasms 18931683 miR-15a: The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities 2071 hsa-mir-16-1 Prostatic Neoplasms 18931683 miR-16: The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities 2072 hsa-mir-16-2 Prostatic Neoplasms 18931683 miR-16: The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities 2073 hsa-mir-182 Prostatic Neoplasms 19267923 miR-182: with high analytical sensitivity and specificity 2074 hsa-mir-21 Prostatic Neoplasms 19302977 miR-21: MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells 2075 hsa-mir-21 Prostatic Neoplasms 19267923 miR-21: with high analytical sensitivity and specificity 2076 hsa-mir-221 Prostatic Neoplasms 19267923 miR-221: with high analytical sensitivity and specificity 2077 hsa-mir-222 Prostatic Neoplasms 19351827 miR-222: Overexpression 2078 hsa-mir-222 Prostatic Neoplasms 19267923 miR-222: with high analytical sensitivity and specificity 2079 hsa-mir-25 Prostatic Neoplasms 18676839 miR-25: significantly higher expression 2080 hsa-mir-32 Prostatic Neoplasms 18676839 miR-32: significantly higher expression 2081 hsa-mir-34c Prostatic Neoplasms 18668526 miR-34c: Significant changes in Radiation modulation 2082 hsa-mir-373 Prostatic Neoplasms 19158933 miR-373: MicroRNAs 373 and 520c Are Downregulated in Prostate Cancer, Suppress CD44 2083 hsa-mir-520c Prostatic Neoplasms 19158933 miR-520c: MicroRNAs 373 and 520c Are Downregulated in Prostate Cancer, Suppress CD44 2084 hsa-mir-521-1 Prostatic Neoplasms 18668526 miR-521: Significant changes in Radiation modulation 2085 hsa-mir-521-2 Prostatic Neoplasms 18668526 miR-521: Significant changes in Radiation modulation 2086 hsa-mir-93 Prostatic Neoplasms 18676839 miR-93: significantly higher expression 2087 hsa-mir-135b Prostatic Neoplasms 18949015 miR-135b: up-regulated 2088 hsa-mir-145 Prostatic Neoplasms 18949015 miR-145: down-regulated 2089 hsa-mir-194-1 Prostatic Neoplasms 18949015 miR-194: up-regulated 2090 hsa-mir-194-2 Prostatic Neoplasms 18949015 miR-194: up-regulated 2091 hsa-mir-221 Prostatic Neoplasms 18949015 miR-221: down-regulated 2092 hsa-mir-222 Prostatic Neoplasms 18949015 miR-222: down-regulated 2093 hsa-mir-23b Prostatic Neoplasms 18949015 miR-23b: down-regulated 2094 hsa-mir-221 Prostatic Neoplasms 19107213 miR-221: The inhibition of the highly expressed miR-221 and miR-222 impairs the growth of prostate carcinoma xenografts in mice 2095 hsa-mir-222 Prostatic Neoplasms 19107213 miR-222: The inhibition of the highly expressed miR-221 and miR-222 impairs the growth of prostate carcinoma xenografts in mice 2096 hsa-mir-101-1 Prostatic Neoplasms 19285253 miR-101: decrease of miR-101 leads to the overexpression of EZH2 2097 hsa-mir-101-2 Prostatic Neoplasms 19285253 miR-101: decrease of miR-101 leads to the overexpression of EZH2 2098 hsa-mir-125b-1 Rectal Neoplasms 18695884 miR-125b: frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer 2099 hsa-mir-125b-2 Rectal Neoplasms 18695884 miR-125b: frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer 2100 hsa-mir-137 Rectal Neoplasms 18695884 miR-137: frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer 2101 hsa-mir-141 Carcinoma, Renal Cell 18925646 miR-141: down-regulation 2102 hsa-mir-200c Carcinoma, Renal Cell 18925646 miR-200c: down-regulation 2103 hsa-mir-1-1 Retinal Degeneration 18834879 miR-1: upregulation 2104 hsa-mir-1-2 Retinal Degeneration 18834879 miR-1: upregulation 2105 hsa-mir-133b Retinal Degeneration 18834879 miR-133: upregulation 2106 hsa-mir-142 Retinal Degeneration 18834879 miR-142: upregulation 2107 hsa-mir-182 Retinal Degeneration 18834879 miR-182: decreased expression 2108 hsa-mir-183 Retinal Degeneration 18834879 miR-183: decreased expression 2109 hsa-mir-96 Retinal Degeneration 18834879 miR-96: decreased expression 2110 hsa-mir-29a Rhabdomyosarcoma 18977326 miR-29: NF-kappaB-YY1-miR-29 regulatory circuitry 2111 hsa-mir-146a Arthritis, Rheumatoid 18759964 miR-146a: Upregulated miR-146a expression in peripheral blood mononuclear cells 2112 hsa-mir-346 Schizophrenia 19264453 miR-346: Expression of both miR-346 and GRID1 is lower in SZ patients than that in normal controls 2113 hsa-mir-196b Neutropenia 19278956 miR-196b: regulated by Gfi1 2114 hsa-mir-21 Neutropenia 19278956 miR-21: regulated by Gfi1 2115 hsa-mir-302a Skin Neoplasms 18755840 miR-302: Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state 2116 hsa-mir-302b Skin Neoplasms 18755840 miR-302: Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state 2117 hsa-mir-302c Skin Neoplasms 18755840 miR-302: Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state 2118 hsa-mir-302d Skin Neoplasms 18755840 miR-302: Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state 2119 hsa-mir-1-1 Hypertension 18690400 miR-1: deregulation 2120 hsa-mir-1-2 Hypertension 18690400 miR-1: deregulation 2121 hsa-mir-133a-1 Hypertension 18690400 miR-133a: deregulation 2122 hsa-mir-133a-2 Hypertension 18690400 miR-133a: deregulation 2123 hsa-mir-155 Hypertension 18690400 miR-155: deregulation 2124 hsa-mir-208b Hypertension 18690400 miR-208: deregulation 2125 hsa-mir-184 Tongue Neoplasms 19219377 miR-184: overexpressed 2126 hsa-mir-17 Leukemia-Lymphoma, Adult T-Cell 19148830 miR-17: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia 2127 hsa-mir-18a Leukemia-Lymphoma, Adult T-Cell 19148830 miR-18a: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia 2128 hsa-mir-19a Leukemia-Lymphoma, Adult T-Cell 19148830 miR-19a: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia 2129 hsa-mir-19b-1 Leukemia-Lymphoma, Adult T-Cell 19148830 miR-19b: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia 2130 hsa-mir-19b-2 Leukemia-Lymphoma, Adult T-Cell 19148830 miR-19b: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia 2131 hsa-mir-20a Leukemia-Lymphoma, Adult T-Cell 19148830 miR-20a: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia 2132 hsa-mir-92a-1 Leukemia-Lymphoma, Adult T-Cell 19148830 miR-92a: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia 2133 hsa-mir-92a-2 Leukemia-Lymphoma, Adult T-Cell 19148830 miR-92a: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia 2134 hsa-mir-146a Thyroid Neoplasms 19164563 miR-146a: SNP rs2910164 contribute to thyroid cancer 2135 hsa-mir-142 Lung Neoplasms 19228723 miR-142-5p: were repressed, overexpression can inhibitu lung cancer growth 2136 hsa-mir-145 Lung Neoplasms 19228723 miR-145: were repressed, overexpression can inhibitu lung cancer growth 2137 hsa-mir-34c Lung Neoplasms 19228723 miR-34c: were repressed, overexpression can inhibitu lung cancer growth 2138 hsa-let-7a-1 Neoplasms 18560417 let-7a: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication 2139 hsa-let-7a-2 Neoplasms 18560417 let-7a: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication 2140 hsa-let-7a-3 Neoplasms 18560417 let-7a: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication 2141 hsa-let-7b Neoplasms 18560417 let-7b: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication 2142 hsa-let-7c Neoplasms 18560417 let-7c: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication 2143 hsa-let-7d Neoplasms 18560417 let-7d: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication 2144 hsa-let-7e Neoplasms 18560417 let-7e: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication 2145 hsa-let-7f-1 Neoplasms 18560417 let-7f: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication 2146 hsa-let-7f-2 Neoplasms 18560417 let-7f: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication 2147 hsa-let-7g Neoplasms 18560417 let-7g: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication 2148 hsa-let-7i Neoplasms 18560417 let-7i: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication 2149 hsa-mir-106b Neoplasms 18922889 miR-106b: key modulators of TGFbeta signaling 2150 hsa-mir-17 Neoplasms 18922889 miR-17: key modulators of TGFbeta signaling 2151 hsa-mir-18a Neoplasms 18922889 miR-18a: key modulators of TGFbeta signaling 2152 hsa-mir-19a Neoplasms 18922889 miR-19a: key modulators of TGFbeta signaling 2153 hsa-mir-19b-1 Neoplasms 18922889 miR-19b: key modulators of TGFbeta signaling 2154 hsa-mir-19b-2 Neoplasms 18922889 miR-19b: key modulators of TGFbeta signaling 2155 hsa-mir-20a Neoplasms 18922889 miR-20a: key modulators of TGFbeta signaling 2156 hsa-mir-21 Neoplasms 18850008 miR-21: oncomir, An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation 2157 hsa-mir-25 Neoplasms 18922889 miR-25: key modulators of TGFbeta signaling 2158 hsa-mir-29a Neoplasms 19079265 miR-29a: miR-29 directly suppress p85 alpha and CDC42, both of which negatively regulate p53 2159 hsa-mir-34b Neoplasms 18768788 miR-34b: were found to undergo specific hypermethylation-associated silencing in cancer cells compared with normal tissues 2160 hsa-mir-34c Neoplasms 18768788 miR-34c: were found to undergo specific hypermethylation-associated silencing in cancer cells compared with normal tissues 2161 hsa-mir-520b Neoplasms 19109132 miR-520b: miR-520b was induced by IFN-gamma, leading to a reduction in MICA surface protein levels 2162 hsa-mir-9-1 Neoplasms 18768788 miR-9: were found to undergo specific hypermethylation-associated silencing in cancer cells compared with normal tissues 2163 hsa-mir-9-2 Neoplasms 18768788 miR-9: were found to undergo specific hypermethylation-associated silencing in cancer cells compared with normal tissues 2164 hsa-mir-92a-1 Neoplasms 18922889 miR-92a: key modulators of TGFbeta signaling 2165 hsa-mir-92a-2 Neoplasms 18922889 miR-92a: key modulators of TGFbeta signaling 2166 hsa-mir-93 Neoplasms 18922889 miR-93: key modulators of TGFbeta signaling 2167 hsa-mir-9-3 Neoplasms 18768788 miR-9: were found to undergo specific hypermethylation-associated silencing in cancer cells compared with normal tissues 2168 hsa-mir-34a Melanoma 19029026 miR-34a: MicroRNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met 2169 hsa-mir-155 Waldenstrom Macroglobulinemia 19074725 miR-155: increased expression 2170 hsa-mir-184 Waldenstrom Macroglobulinemia 19074725 miR-184: increased expression 2171 hsa-mir-206 Waldenstrom Macroglobulinemia 19074725 miR-206: increased expression 2172 hsa-mir-363 Waldenstrom Macroglobulinemia 19074725 miR-363*: increased expression 2173 hsa-mir-494 Waldenstrom Macroglobulinemia 19074725 miR-494: increased expression 2174 hsa-mir-542 Waldenstrom Macroglobulinemia 19074725 miR-542-3p: increased expression 2175 hsa-mir-9-1 Waldenstrom Macroglobulinemia 19074725 miR-9*: decreased expression 2176 hsa-mir-9-2 Waldenstrom Macroglobulinemia 19074725 miR-9*: decreased expression 2177 hsa-mir-9-3 Waldenstrom Macroglobulinemia 19074725 miR-9*: decreased expression 2178 hsa-let-7g Lung Neoplasms 19745602 increased with response to ionizing radiation when knockdown LIN28B 2179 hsa-mir-206 Rhabdomyosarcoma 19710019 inhibits rhabdomyosarcoma through downregulating c-Met 2180 hsa-mir-122 Carcinoma, Hepatocellular 19726678 The liver specific miR-122 is frequently suppressed in primary hepatocellular carcinomas (HCCs). ADAM-10 (a distintegrin and metalloprotease family-10), SRF (serum response factor), and Igf1R (insulin like growth factor 1 receptor) that promote tumorigenesis were validated as targets of miR- 122 and were repressed by the microRNA. 2181 hsa-mir-100 Nasopharyngeal Neoplasms 19739117 downregulated 2182 hsa-mir-140 Colonic Neoplasms 19734943 high-throughput microRNA (miRNA) expression analysis revealed that the expression of miR-140 was associated with chemosensitivity in osteosarcoma tumor xenografts 2183 hsa-let-7d Cocaine-Related Disorders 19703567 downregulated;These miRNAs target many genes involved in cocaine addiction. Precursor and mature miRNA quantification by qRT-PCR showed that miR-124 and let-7d are significantly downregulated 2184 hsa-mir-206 Neoplasms 19723635 The inhibition of cancer cell migration and foci formation by miR-206 strongly suggests that miR-206 may function as a novel tumor suppressor. 2185 hsa-mir-21 Prostatic Neoplasms 19738047 hsa-miR-21: an androgen receptor-regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth 2186 hsa-mir-298 Cerebral Hemorrhage 19724284 correlate 2187 hsa-mir-155 Cerebral Hemorrhage 19724284 correlate 2188 hsa-mir-34a Lung Neoplasms 19736307 relevant to the diagnosis 2189 hsa-mir-500a Carcinoma, Hepatocellular 19737067 oncofetal miRNA relevant to the diagnosis 2190 hsa-mir-151a Leukemia, Lymphocytic, Chronic, B-Cell 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia 2191 hsa-mir-34a Leukemia, Lymphocytic, Chronic, B-Cell 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia 2192 hsa-mir-29c Leukemia, Lymphocytic, Chronic, B-Cell 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia 2193 hsa-mir-29b-1 Leukemia, Lymphocytic, Chronic, B-Cell 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia 2194 hsa-mir-148a Leukemia, Lymphocytic, Chronic, B-Cell 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia 2195 hsa-mir-146a Leukemia, Lymphocytic, Chronic, B-Cell 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia 2196 hsa-mir-640 Leukemia, Lymphocytic, Chronic, B-Cell 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia 2197 hsa-mir-140 Arthritis 19714579 down-regulated IL-1beta-induced ADAMTS5 2198 hsa-mir-15a Arthritis 19714650 induction of apoptosis in the synovium of mice,suppresses apoptosis through inhibition of Bcl-2 2199 hsa-mir-494 Prion Diseases 19712440 upregulated 2200 hsa-mir-21 Adenocarcinoma 19737943 predictors of prognosis 2201 hsa-mir-1-1 Rhabdomyosarcoma 19710019 inhibits rhabdomyosarcoma through downregulating c-Met 2202 hsa-mir-1-2 Rhabdomyosarcoma 19710019 inhibits rhabdomyosarcoma through downregulating c-Met 2203 hsa-mir-200a Meningioma 19703647 Down-regulation Promotes Tumor Growth by reducing E-cadherin and Activating the Wnt/{beta} catenin Signaling Pathway 2204 hsa-mir-21 Myocardial Infarction 19706597 hsa-miR-21:a remarkable example of MicroRNA expression signature; downregulated in infarcted areas, upregulated in border areas 2205 hsa-mir-122 Carcinoma, Hepatocellular 19711427 down-regulation at early stage 2206 hsa-mir-122 Stroke 19745058 diagnostical sensitivity: illustrated liver and muscle toxicity 2207 hsa-mir-133a-1 Stroke 19745058 diagnostical sensitivity: illustrated liver and muscle toxicity 2208 hsa-mir-133a-2 Stroke 19745058 diagnostical sensitivity: illustrated liver and muscle toxicity 2209 hsa-mir-124-1 Stroke 19745058 diagnostical sensitivity:illustrated injuries in liver, muscle, and brain 2210 hsa-mir-124-2 Stroke 19745058 diagnostical sensitivity:illustrated injuries in liver, muscle, and brain 2211 hsa-mir-124-3 Stroke 19745058 diagnostical sensitivity:illustrated injuries in liver, muscle, and brain 2212 hsa-mir-125b-1 Breast Neoplasms 19738052 hsa-miR-125b binding site in BMPR1B is Associated with Breast cancer pathogenesis 2213 hsa-mir-125b-2 Breast Neoplasms 19738052 hsa-miR-125b binding site in BMPR1B is Associated with Breast cancer pathogenesis 2214 hsa-mir-140 Osteosarcoma 19734943 high-throughput microRNA (miRNA) expression analysis revealed that the expression of miR-140 was associated with chemosensitivity in osteosarcoma tumor xenografts 2215 hsa-mir-145 Atherosclerosis 19744308 downregulated 2216 hsa-mir-15a Schizophrenia 19721432 upregulated 2217 hsa-mir-15b Schizophrenia 19721432 upregulated 2218 hsa-mir-196a-1 Adenocarcinoma 19723895 uperegulated 2219 hsa-mir-196a-2 Adenocarcinoma 19723895 uperegulated 2220 hsa-mir-155 Carcinoma, Hepatocellular 19711427 Real-time reverse transcription polymerase chain reaction (RT-PCR) analysis demonstrated up-regulation of oncogenic miR-155, miR-221/222, and miR-21 and down-regulation of the most abundant liver-specific miR-122 at early stages of hepatocarcinogenesis. 2221 hsa-mir-221 Carcinoma, Hepatocellular 19711427 Real-time reverse transcription polymerase chain reaction (RT-PCR) analysis demonstrated up-regulation of oncogenic miR-155, miR-221/222, and miR-21 and down-regulation of the most abundant liver-specific miR-122 at early stages of hepatocarcinogenesis. 2222 hsa-mir-222 Carcinoma, Hepatocellular 19711427 Real-time reverse transcription polymerase chain reaction (RT-PCR) analysis demonstrated up-regulation of oncogenic miR-155, miR-221/222, and miR-21 and down-regulation of the most abundant liver-specific miR-122 at early stages of hepatocarcinogenesis. 2223 hsa-mir-21 Carcinoma, Hepatocellular 19711427 Real-time reverse transcription polymerase chain reaction (RT-PCR) analysis demonstrated up-regulation of oncogenic miR-155, miR-221/222, and miR-21 and down-regulation of the most abundant liver-specific miR-122 at early stages of hepatocarcinogenesis. 2224 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 19723889 a role for the mir-15a/16-1 cluster in cell cycle regulation and suggest that these mature microRNAs in both the New Zealand Black model and human CLL may be targets for therapeutic efficacy in this disease. 2225 hsa-mir-16-2 Leukemia, Lymphocytic, Chronic, B-Cell 19723889 a role for the mir-15a/16-1 cluster in cell cycle regulation and suggest that these mature microRNAs in both the New Zealand Black model and human CLL may be targets for therapeutic efficacy in this disease. 2226 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 19723889 a role for the mir-15a/16-1 cluster in cell cycle regulation and suggest that these mature microRNAs in both the New Zealand Black model and human CLL may be targets for therapeutic efficacy in this disease. 2227 hsa-mir-181a-1 Leukemia, Lymphocytic, Chronic, B-Cell 19717645 high expression 2228 hsa-mir-181a-2 Leukemia, Lymphocytic, Chronic, B-Cell 19717645 high expression 2229 hsa-mir-181a-1 Cocaine-Related Disorders 19703567 miR-124, let-7d and miR-181a may be involved in a complex feedback loop with cocaine-responsive plasticity genes 2230 hsa-mir-181a-2 Cocaine-Related Disorders 19703567 miR-124, let-7d and miR-181a may be involved in a complex feedback loop with cocaine-responsive plasticity genes 2231 hsa-mir-124-3 Cocaine-Related Disorders 19703567 downregulated;These miRNAs target many genes involved in cocaine addiction. Precursor and mature miRNA quantification by qRT-PCR showed that miR-124 and let-7d are significantly downregulated 2232 hsa-mir-124-1 Cocaine-Related Disorders 19703567 downregulated;These miRNAs target many genes involved in cocaine addiction. Precursor and mature miRNA quantification by qRT-PCR showed that miR-124 and let-7d are significantly downregulated 2233 hsa-mir-124-2 Cocaine-Related Disorders 19703567 downregulated;These miRNAs target many genes involved in cocaine addiction. Precursor and mature miRNA quantification by qRT-PCR showed that miR-124 and let-7d are significantly downregulated 2234 hsa-mir-21 Adenocarcinoma 19730150 Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma. 2235 hsa-mir-221 Adenocarcinoma 19730150 Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma. 2236 hsa-mir-21 Adenocarcinoma 19723895 profiled four miRNAs, miR-21, miR-210, miR-155, and miR-196a, all implicated in the development of pancreatic cancer with either proven or predicted target genes involved in critical cancer-associated cellular pathways. 2237 hsa-mir-210 Adenocarcinoma 19723895 profiled four miRNAs, miR-21, miR-210, miR-155, and miR-196a, all implicated in the development of pancreatic cancer with either proven or predicted target genes involved in critical cancer-associated cellular pathways. 2238 hsa-mir-155 Adenocarcinoma 19723895 miR-155 has recently been identified as a candidate biomarker of early pancreatic neoplasia 2239 hsa-mir-196a-1 Adenocarcinoma 19723895 elevated expression of miR196a has been shown to parallel progression of disease 2240 hsa-mir-196a-2 Adenocarcinoma 19723895 elevated expression of miR196a has been shown to parallel progression of disease 2241 hsa-mir-223 Leukemia, Lymphocytic, Chronic, B-Cell 19717645 low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion 2242 hsa-mir-29c Leukemia, Lymphocytic, Chronic, B-Cell 19717645 low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion 2243 hsa-mir-29b-1 Leukemia, Lymphocytic, Chronic, B-Cell 19717645 low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion 2244 hsa-mir-29b-2 Leukemia, Lymphocytic, Chronic, B-Cell 19717645 low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion 2245 hsa-mir-181b-1 Leukemia, Lymphocytic, Chronic, B-Cell 19717645 low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion 2246 hsa-mir-181c Leukemia, Lymphocytic, Chronic, B-Cell 19717645 low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion 2247 hsa-mir-181a-1 Leukemia, Lymphocytic, Chronic, B-Cell 19717645 low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion 2248 hsa-mir-181b-2 Leukemia, Lymphocytic, Chronic, B-Cell 19717645 low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion 2249 hsa-mir-362 Cerebral Hemorrhage 19724284 correlate 2250 hsa-mir-34a Pancreatic Neoplasms 19714243 inhibits tumor-initiating cells. 2251 hsa-mir-34b Pancreatic Neoplasms 19714243 inhibits tumor-initiating cells. 2252 hsa-mir-34c Pancreatic Neoplasms 19714243 inhibits tumor-initiating cells. 2253 hsa-mir-16-1 Prostatic Neoplasms 19738602 microRNA (miR)-16, which is expressed at lower levels in prostate cancer cells, affects the proliferation of human prostate cancer cell lines both in vitro and in vivo 2254 hsa-mir-16-2 Prostatic Neoplasms 19738602 microRNA (miR)-16, which is expressed at lower levels in prostate cancer cells, affects the proliferation of human prostate cancer cell lines both in vitro and in vivo 2255 hsa-mir-155 Leukemia, Lymphocytic, Chronic, B-Cell 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia 2256 hsa-mir-208a Cardiomegaly 19726871 overexpress 2257 hsa-mir-128-1 Neuroblastoma 19713529 reduce cell motility and invasiveness 2258 hsa-mir-128-2 Neuroblastoma 19713529 reduce cell motility and invasiveness 2259 hsa-mir-146b Leukemia, Lymphocytic, Chronic, B-Cell 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia 2260 hsa-mir-342 Prion Diseases 19712440 upregulated 2261 hsa-mir-17 Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression 2262 hsa-mir-18a Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression 2263 hsa-mir-19a Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression 2264 hsa-mir-19b-1 Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression 2265 hsa-mir-19b-2 Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression 2266 hsa-mir-20a Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression 2267 hsa-mir-17 Breast Neoplasms 20406904 microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling 2268 hsa-mir-20a Breast Neoplasms 20406904 microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling 2269 hsa-mir-20b Breast Neoplasms 20406904 microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling 2270 hsa-mir-17 Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2271 hsa-mir-18a Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2272 hsa-mir-18b Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2273 hsa-mir-20a Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2274 hsa-mir-20b Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2275 hsa-mir-106a Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2276 hsa-mir-106b Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2277 hsa-mir-93 Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2278 hsa-mir-183 Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2279 hsa-mir-182 Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2280 hsa-mir-367 Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2281 hsa-mir-302a Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2282 hsa-mir-302b Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2283 hsa-mir-302c Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2284 hsa-mir-302d Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2285 hsa-mir-371a Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2286 hsa-mir-373 Glioma 20406893 miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas, 2287 hsa-mir-148a Prostatic Neoplasms 20406806 MiR-148a attenuates paclitaxel-resistance of hormone-refractory, drug-resistant prostate cancer PC3 cells by regulating MSK1 expression 2288 hsa-mir-23a Leukemia, Myeloid 20399246 the 23a cluster is the first downstream miRNA target implicated in regulating the development of myeloid versus lymphoid cells. 2289 hsa-mir-21 Leukemia, Lymphocytic, Chronic, B-Cell 20393129 microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival 2290 hsa-mir-22 Prostatic Neoplasms 20388916 We showed that miR-22 and the miR-106b~25 cluster are aberrantly overexpressed in human prostate cancer 2291 hsa-mir-106b Prostatic Neoplasms 20388916 We showed that miR-22 and the miR-106b~25 cluster are aberrantly overexpressed in human prostate cancer 2292 hsa-mir-25 Prostatic Neoplasms 20388916 We showed that miR-22 and the miR-106b~25 cluster are aberrantly overexpressed in human prostate cancer 2293 hsa-mir-93 Prostatic Neoplasms 20388916 We showed that miR-22 and the miR-106b~25 cluster are aberrantly overexpressed in human prostate cancer 2294 hsa-mir-221 Breast Neoplasms 20388878 These findings suggest that the negative regulatory loop involving miR-221-222 and ERalpha may confer proliferative advantage and migratory activity to breast cancer cells and promote the transition from ER-positive to ER-negative tumors 2295 hsa-mir-222 Breast Neoplasms 20388878 These findings suggest that the negative regulatory loop involving miR-221-222 and ERalpha may confer proliferative advantage and migratory activity to breast cancer cells and promote the transition from ER-positive to ER-negative tumors 2296 hsa-mir-146a Inflammation 20384865 functional role of miR-146a in innate immune, inflammatory response, virus infection and human diseases 2297 hsa-mir-650 Stomach Neoplasms 20381459 we show that miR-650 is involved in lymphatic and distant metastasis in human gastric cancer 2298 hsa-mir-106b Child Development Disorders, Pervasive 20374639 down-regulation 2299 hsa-mir-23a Child Development Disorders, Pervasive 20374639 up-regulation 2300 hsa-mir-219-1 Child Development Disorders, Pervasive 20374639 Putative gene targets (ID3 and PLK2) of two RT-PCR-confirmed brain-specific miRNAs (hsa-miR-29b and hsa-miR-219-5p),were validated by miRNA overexpression or knockdown assays 2301 hsa-mir-219-2 Child Development Disorders, Pervasive 20374639 Putative gene targets (ID3 and PLK2) of two RT-PCR-confirmed brain-specific miRNAs (hsa-miR-29b and hsa-miR-219-5p),were validated by miRNA overexpression or knockdown assays 2302 hsa-mir-21 Stomach Neoplasms 20372781 Expression of miR-21 in cancer tissues was significantly higher than in non-cancer tissues 2303 hsa-mir-155 Breast Neoplasms 20371610 MicroRNA-155 regulates cell survival, growth and chemosensitivity by targeting FOXO3a in breast cancer 2304 hsa-mir-122 Hepatitis C 20371461 miR-122, a major regulatory RNA in liver that fine-tunes the expression of over 100 cellular genes and enhances HCV replication 2305 hsa-mir-122 Liver Neoplasms 20371461 miR-122, a major regulatory RNA in liver that fine-tunes the expression of over 100 cellular genes and enhances HCV replication 2306 hsa-mir-21 Neoplasms 20370992 over-expressed 2307 hsa-mir-182 Neoplasms 20370992 over-expressed 2308 hsa-let-7a-1 Neoplasms 20370992 over-expressed 2309 hsa-let-7a-2 Neoplasms 20370992 over-expressed 2310 hsa-let-7a-3 Neoplasms 20370992 over-expressed 2311 hsa-mir-145 Neoplasms 20370992 under-expressed 2312 hsa-mir-155 Neoplasms 20370992 under-expressed 2313 hsa-mir-204 Head and Neck Neoplasms 20369013 Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis 2314 hsa-mir-602 Hepatitis B 20364114 MicroRNA-602 regulating tumor suppressive gene RASSF1A is overexpressed in hepatitis B virus-infected liver and hepatocellular carcinoma 2315 hsa-mir-602 Carcinoma, Hepatocellular 20364114 MicroRNA-602 regulating tumor suppressive gene RASSF1A is overexpressed in hepatitis B virus-infected liver and hepatocellular carcinoma 2316 hsa-mir-429 Glomerulonephritis, IGA 20364043 down-regulated 2317 hsa-mir-200b Glomerulonephritis, IGA 20364043 down-regulated 2318 hsa-mir-200a Glomerulonephritis, IGA 20364043 down-regulated 2319 hsa-mir-21 Lung Neoplasms 20363096 upregulated; Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis 2320 hsa-mir-143 Lung Neoplasms 20363096 downregulated; Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis 2321 hsa-mir-181a-1 Lung Neoplasms 20363096 downregulated; Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis 2322 hsa-mir-181a-2 Lung Neoplasms 20363096 downregulated; Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis 2323 hsa-mir-210 Pancreatic Neoplasms 20360935 Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer 2324 hsa-mir-193a Melanoma 20357817 In melanomas, miR-193a, miR-338, and miR-565 were underexpressed in cases with a BRAF mutation. 2325 hsa-mir-338 Melanoma 20357817 In melanomas, miR-193a, miR-338, and miR-565 were underexpressed in cases with a BRAF mutation. 2326 hsa-mir-193b Melanoma 20357817 Furthermore, low expression of miR-191 and high expression of miR-193b were associated with poor melanoma-specific survive 2327 hsa-mir-191 Melanoma 20357817 Furthermore, low expression of miR-191 and high expression of miR-193b were associated with poor melanoma-specific survive 2328 hsa-mir-21 Granulosa Cell Tumor 20357270 MicroRNA 21 Blocks Apoptosis in Mouse Periovulatory Granulosa Cells 2329 hsa-mir-516a-1 Ovarian Neoplasms 20354523 Three dysregulated miRNAs control kallikrein 10 expression and cell proliferation in ovarian cancer 2330 hsa-mir-516a-2 Ovarian Neoplasms 20354523 Three dysregulated miRNAs control kallikrein 10 expression and cell proliferation in ovarian cancer 2331 hsa-mir-224 Ovarian Neoplasms 20354523 Three dysregulated miRNAs control kallikrein 10 expression and cell proliferation in ovarian cancer 2332 hsa-let-7f-1 Ovarian Neoplasms 20354523 Three dysregulated miRNAs control kallikrein 10 expression and cell proliferation in ovarian cancer 2333 hsa-let-7f-2 Ovarian Neoplasms 20354523 Three dysregulated miRNAs control kallikrein 10 expression and cell proliferation in ovarian cancer 2334 hsa-mir-155 Breast Neoplasms 20354188 MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene 2335 hsa-mir-143 Prostatic Neoplasms 20353999 Our data indicate that miR-143 and miR-145 are involved in the regulation of MYO6 expression and possibly in the development of prostate cancer 2336 hsa-mir-145 Prostatic Neoplasms 20353999 Our data indicate that miR-143 and miR-145 are involved in the regulation of MYO6 expression and possibly in the development of prostate cancer 2337 hsa-mir-181a-1 Glioblastoma 20353279 MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients 2338 hsa-mir-181a-2 Glioblastoma 20353279 MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients 2339 hsa-mir-181b-1 Glioblastoma 20353279 MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients 2340 hsa-mir-181b-2 Glioblastoma 20353279 MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients 2341 hsa-mir-181c Glioblastoma 20353279 MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients 2342 hsa-mir-181d Glioblastoma 20353279 MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients 2343 hsa-mir-10b Neoplasms 20351690 Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model 2344 hsa-mir-155 Colorectal Neoplasms, Hereditary Nonpolyposis 20351277 Modulation of mismatch repair and genomic stability by miR-155 2345 hsa-mir-34a Carcinoma 20351093 MicroRNA-34a suppresses invasion through down-regulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells 2346 hsa-mir-34a Choriocarcinoma 20351093 MicroRNA-34a suppresses invasion through down-regulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells 2347 hsa-mir-106a Stomach Neoplasms 20349219 a significant correlation between the number of cancer cells and the levels of both miR-106a (r = -0.906, p = 0.037) and miR-17 (r = -0.912, p = 0.031) was found. 2348 hsa-mir-17 Stomach Neoplasms 20349219 a significant correlation between the number of cancer cells and the levels of both miR-106a (r = -0.906, p = 0.037) and miR-17 (r = -0.912, p = 0.031) was found. 2349 hsa-let-7g Carcinoma, Hepatocellular 20347499 The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2350 hsa-let-7a-1 Carcinoma, Hepatocellular 20347499 The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2351 hsa-let-7a-2 Carcinoma, Hepatocellular 20347499 The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2352 hsa-let-7f-1 Carcinoma, Hepatocellular 20347499 The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2353 hsa-let-7d Carcinoma, Hepatocellular 20347499 The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2354 hsa-let-7i Carcinoma, Hepatocellular 20347499 The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2355 hsa-let-7e Carcinoma, Hepatocellular 20347499 The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2356 hsa-let-7c Carcinoma, Hepatocellular 20347499 The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2357 hsa-let-7b Carcinoma, Hepatocellular 20347499 The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2358 hsa-let-7f-2 Carcinoma, Hepatocellular 20347499 The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2359 hsa-let-7a-3 Carcinoma, Hepatocellular 20347499 The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2360 hsa-mir-30e Schizophrenia 20347265 MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia 2361 hsa-mir-21 Breast Neoplasms 20346171 our data suggests that miR-21 could promote invasion in breast cancer cells via its regulation of TIMP3 2362 hsa-let-7g Carcinoma, Hepatocellular 20338660 Let-7g targets collagen type I alpha2 and inhibits cell migration in hepatocellular carcinoma. 2363 hsa-mir-21 Carcinoma 20335152 Expression of microRNA-21 in ovarian epithelial carcinoma and its clinical significance 2364 hsa-mir-155 Adenocarcinoma 20332664 Aberrant MicroRNA-155 expression is an early event in the multistep progression of pancreatic adenocarcinoma 2365 hsa-mir-371a Carcinoma 20332240 overexpressed 2366 hsa-mir-372 Carcinoma 20332240 overexpressed 2367 hsa-mir-373 Carcinoma 20332240 overexpressed 2368 hsa-mir-302a Carcinoma 20332240 overexpressed 2369 hsa-mir-302b Carcinoma 20332240 overexpressed 2370 hsa-mir-302c Carcinoma 20332240 overexpressed 2371 hsa-mir-302d Carcinoma 20332240 overexpressed 2372 hsa-mir-302e Carcinoma 20332240 overexpressed 2373 hsa-mir-302f Carcinoma 20332240 overexpressed 2374 hsa-mir-1296 Prostatic Neoplasms 20332239 Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer 2375 hsa-mir-129-2 Stomach Neoplasms 20331975 We also found that inactivation of SOX4 by siRNA and restoration of miR-129-2 induced apoptosis in gastric cancer cells. 2376 hsa-mir-21 Breast Neoplasms 20331864 up-regulated in male breast cancer 2377 hsa-mir-519d Breast Neoplasms 20331864 up-regulated in male breast cancer 2378 hsa-mir-183 Breast Neoplasms 20331864 up-regulated in male breast cancer 2379 hsa-mir-197 Breast Neoplasms 20331864 up-regulated in male breast cancer 2380 hsa-mir-493 Breast Neoplasms 20331864 up-regulated in male breast cancer 2381 hsa-mir-145 Breast Neoplasms 20331864 down-regulated in male breast cancer 2382 hsa-mir-497 Breast Neoplasms 20331864 down-regulated in male breast cancer 2383 hsa-let-7g Carcinoma, Hepatocellular 20309945 Hsa-let-7g inhibits proliferation of hepatocellular carcinoma Cells by down-regulation of c-Myc and Up-regulation of p16(INK4A). 2384 hsa-mir-126 Adenocarcinoma 20309880 we found that miR-126 expression was associated with tumor cell de-differentiation and lymph node metastasis, 2385 hsa-mir-16-2 Adenocarcinoma 20309880 miR-16-2 was associated with lymph node metastasis 2386 hsa-mir-195 Adenocarcinoma 20309880 miR-195p was associated with higher pathologic disease stages in patients with esophageal adenocarcinoma 2387 hsa-mir-210 Ischemia 20308562 demonstrated a key role of miR-210 in limiting keratinocyte proliferation 2388 hsa-mir-17 Glioblastoma 20305691 De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures 2389 hsa-mir-18a Glioblastoma 20305691 De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures 2390 hsa-mir-19a Glioblastoma 20305691 De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures 2391 hsa-mir-19b-1 Glioblastoma 20305691 De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures 2392 hsa-mir-19b-2 Glioblastoma 20305691 De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures 2393 hsa-mir-20a Glioblastoma 20305691 De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures 2394 hsa-mir-151a Glioblastoma 20305651 significantly increases HCC cell migration and invasion in vitro and in vivo, mainly through miR-151-5p, but not through miR-151-3p 2395 hsa-mir-193b Melanoma 20304954 MicroRNA-193b Represses Cell Proliferationand Regulates Cyclin D1 in Melanoma 2396 hsa-mir-21 Multiple Myeloma 20302778 miR-21 acts as an oncogene and miR-30b a tumor suppressor gene in MM 2397 hsa-mir-30b Multiple Myeloma 20302778 miR-21 acts as an oncogene and miR-30b a tumor suppressor gene in MM 2398 hsa-mir-21 Adenocarcinoma 20301167 upregulated 2399 hsa-mir-143 Adenocarcinoma 20301167 upregulated 2400 hsa-mir-145 Adenocarcinoma 20301167 upregulated 2401 hsa-mir-215 Adenocarcinoma 20301167 upregulated 2402 hsa-mir-218-1 Stomach Neoplasms 20300657 MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor. 2403 hsa-mir-218-2 Stomach Neoplasms 20300657 MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor. 2404 hsa-mir-128-2 Precursor Cell Lymphoblastic Leukemia-Lymphoma 20237425 A novel mutation in the miR-128b gene reduces miRNA processing and leads to glucocorticoid resistance of MLL-AF4 acute lymphocytic leukemia cells. 2405 hsa-mir-136 Lung Neoplasms 20237410 We found that miR-136, miR-376a, and miR-31 were each prominently overexpressed in murine lung cancers. 2406 hsa-mir-376a-1 Lung Neoplasms 20237410 We found that miR-136, miR-376a, and miR-31 were each prominently overexpressed in murine lung cancers. 2407 hsa-mir-376a-2 Lung Neoplasms 20237410 We found that miR-136, miR-376a, and miR-31 were each prominently overexpressed in murine lung cancers. 2408 hsa-mir-31 Lung Neoplasms 20237410 We found that miR-136, miR-376a, and miR-31 were each prominently overexpressed in murine lung cancers. 2409 hsa-mir-210 Neoplasms 20237418 miR-210 appears to function as a "master microRNA" relevant for the control of diverse functions in the hypoxic state 2410 hsa-mir-210 Inflammation 20237418 miR-210 appears to function as a "master microRNA" relevant for the control of diverse functions in the hypoxic state 2411 hsa-mir-210 Ischemia 20237418 miR-210 appears to function as a "master microRNA" relevant for the control of diverse functions in the hypoxic state 2412 hsa-mir-17 Neoplasms 20234369 the plasma concentrations of miRNAs (miR-17-5p, miR-21, miR-106a, miR-106b) were significantly higher in GC patients than controls 2413 hsa-mir-21 Neoplasms 20234369 the plasma concentrations of miRNAs (miR-17-5p, miR-21, miR-106a, miR-106b) were significantly higher in GC patients than controls 2414 hsa-mir-106a Neoplasms 20234369 the plasma concentrations of miRNAs (miR-17-5p, miR-21, miR-106a, miR-106b) were significantly higher in GC patients than controls 2415 hsa-mir-519c Neoplasms 20233879 MicroRNA-519c suppresses hypoxia-inducible factor-1alpha expression and tumor angiogenesis 2416 hsa-mir-31 Mouth Neoplasms 20233326 plasma miR-31 could be validated a marker of OSCC for diagnostic uses 2417 hsa-let-7b Mouth Neoplasms 20232482 let-7b, but not let-7a, was significantly reduced in the HNSCC cell lines compared to control cells 2418 hsa-mir-138-1 Carcinoma 20232393 we demonstrate that miR-138 suppresses TSCC cell migration and invasion by regulating two key genes in the Rho GTPase signaling pathway 2419 hsa-mir-138-2 Carcinoma 20232393 we demonstrate that miR-138 suppresses TSCC cell migration and invasion by regulating two key genes in the Rho GTPase signaling pathway 2420 hsa-mir-20b Breast Neoplasms 20232316 miR-20b modulates VEGF expression by targeting HIF-1alpha and STAT3 in MCF-7 breast cancer cells 2421 hsa-mir-134 Coronary Artery Disease 20230787 a cluster of three microRNAs including miR-134, miR-198, and miR-370, suggesting that the microRNA signatures can be used to identify patients at risk for acute coronary syndromes 2422 hsa-mir-198 Coronary Artery Disease 20230787 a cluster of three microRNAs including miR-134, miR-198, and miR-370, suggesting that the microRNA signatures can be used to identify patients at risk for acute coronary syndromes 2423 hsa-mir-370 Coronary Artery Disease 20230787 a cluster of three microRNAs including miR-134, miR-198, and miR-370, suggesting that the microRNA signatures can be used to identify patients at risk for acute coronary syndromes 2424 hsa-mir-196a-1 Glioma 20229273 A polymorphism of microRNA196a genome region was associated with decreased risk of glioma in Chinese population 2425 hsa-mir-196a-2 Glioma 20229273 A polymorphism of microRNA196a genome region was associated with decreased risk of glioma in Chinese population 2426 hsa-mir-17 Neoplasms 20227518 mir-17-92, a cluster of miRNAs in the midst of the cancer network 2427 hsa-mir-18a Neoplasms 20227518 mir-17-92, a cluster of miRNAs in the midst of the cancer network 2428 hsa-mir-19a Neoplasms 20227518 mir-17-92, a cluster of miRNAs in the midst of the cancer network 2429 hsa-mir-19b-1 Neoplasms 20227518 mir-17-92, a cluster of miRNAs in the midst of the cancer network 2430 hsa-mir-19b-2 Neoplasms 20227518 mir-17-92, a cluster of miRNAs in the midst of the cancer network 2431 hsa-mir-20a Neoplasms 20227518 mir-17-92, a cluster of miRNAs in the midst of the cancer network 2432 hsa-mir-451a Glioma 20227367 MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells 2433 hsa-mir-375 Liver Neoplasms 20226166 MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties 2434 hsa-mir-21 Lung Neoplasms 20223231 MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC) 2435 hsa-mir-21 Carcinoma 20219416 miR-21 serves as a chemosensitive miRNA, while miR-214 and -23a serve as chemoresistant miRNAs in the tongue squamous cell carcinoma lines 2436 hsa-mir-214 Carcinoma 20219416 miR-21 serves as a chemosensitive miRNA, while miR-214 and -23a serve as chemoresistant miRNAs in the tongue squamous cell carcinoma lines 2437 hsa-mir-23a Carcinoma 20219416 miR-21 serves as a chemosensitive miRNA, while miR-214 and -23a serve as chemoresistant miRNAs in the tongue squamous cell carcinoma lines 2438 hsa-mir-375 Carcinoma 20215506 MicroRNA-375 is downregulated in gastric carcinomas 2439 hsa-mir-146a Inflammation 20214679 miR-146a in reactive astrocytes supports the possible involvement of miRNAs in the modulation of the astroglial inflammatory response 2440 hsa-mir-29a Alzheimer Disease 20202123 miR-29a decreased in Alzheimer disease brains targets neuron navigator-3 2441 hsa-mir-34a Brain Neoplasms 20190569 microRNA-34a is tumor suppressive in brain tumors and glioma stem cells 2442 hsa-mir-34a Glioma 20190569 microRNA-34a is tumor suppressive in brain tumors and glioma stem cells 2443 hsa-mir-146a Sepsis 20188071 Serum miR-146a and miR-223 as potential new biomarkers for sepsis 2444 hsa-mir-223 Sepsis 20188071 Serum miR-146a and miR-223 as potential new biomarkers for sepsis 2445 hsa-mir-191 Ovarian Neoplasms 20167074 Novel genetic variants in miR-191 gene and familial ovarian cancer 2446 hsa-mir-34c Prostatic Neoplasms 20162671 miR-34c is down regulated in prostate cancer and exerts tumor suppressive functions 2447 hsa-mir-21 Prostatic Neoplasms 20160498 The transcriptional regulation of miR-21, its multiple transcripts, and their implication in prostate cancer 2448 hsa-mir-21 Carcinoma 20145181 overexpression 2449 hsa-mir-155 Carcinoma 20145181 overexpression 2450 hsa-let-7i Carcinoma 20145181 overexpression 2451 hsa-mir-142 Carcinoma 20145181 overexpression 2452 hsa-mir-125b-1 Carcinoma 20145181 underexpression 2453 hsa-mir-125b-2 Carcinoma 20145181 underexpression 2454 hsa-mir-375 Carcinoma 20145181 underexpression 2455 hsa-mir-423 Carcinoma 20145181 Upregulation 2456 hsa-mir-106b Carcinoma 20145181 Upregulation 2457 hsa-mir-20a Carcinoma 20145181 Upregulation 2458 hsa-mir-16-1 Carcinoma 20145181 Upregulation 2459 hsa-mir-16-2 Carcinoma 20145181 Upregulation 2460 hsa-mir-10a Carcinoma 20145181 downregulation 2461 hsa-mir-10b Carcinoma 20145181 downregulation 2462 hsa-mir-31 Carcinoma 20145132 miR-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma 2463 hsa-mir-146a Leukemia, Myeloid, Acute 20110180 Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients, 2464 hsa-mir-29b-1 Leukemia, Myeloid, Acute 20110180 Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients, 2465 hsa-mir-29b-2 Leukemia, Myeloid, Acute 20110180 Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients, 2466 hsa-mir-26a-1 Leukemia, Myeloid, Acute 20110180 Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients, 2467 hsa-mir-26a-2 Leukemia, Myeloid, Acute 20110180 Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients, 2468 hsa-mir-196b Leukemia, Myeloid, Acute 20110180 Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients, 2469 hsa-mir-25 Leukemia, Myeloid, Acute 20110180 Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients, 2470 hsa-mir-221 Precursor Cell Lymphoblastic Leukemia-Lymphoma 20110180 Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients, 2471 hsa-mir-181a-1 Precursor Cell Lymphoblastic Leukemia-Lymphoma 20110180 Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients, 2472 hsa-mir-181a-2 Precursor Cell Lymphoblastic Leukemia-Lymphoma 20110180 Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients, 2473 hsa-mir-181c Precursor Cell Lymphoblastic Leukemia-Lymphoma 20110180 Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients, 2474 hsa-mir-146a Precursor Cell Lymphoblastic Leukemia-Lymphoma 20110180 Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients, 2475 hsa-mir-9-1 Stomach Neoplasms 20102618 miR-9 targets NF-kappaB1 and regulates gastric cancer cell growth 2476 hsa-mir-9-2 Stomach Neoplasms 20102618 miR-9 targets NF-kappaB1 and regulates gastric cancer cell growth 2477 hsa-mir-9-3 Stomach Neoplasms 20102618 miR-9 targets NF-kappaB1 and regulates gastric cancer cell growth 2478 hsa-let-7a-1 Lung Neoplasms 20097187 inhibition of proliferation in non-small cell lung cancer 2479 hsa-let-7a-2 Lung Neoplasms 20097187 inhibition of proliferation in non-small cell lung cancer 2480 hsa-let-7a-3 Lung Neoplasms 20097187 inhibition of proliferation in non-small cell lung cancer 2481 hsa-mir-126 Lung Neoplasms 20097187 inhibition of proliferation in non-small cell lung cancer 2482 hsa-mir-145 Lung Neoplasms 20097187 inhibition of proliferation in non-small cell lung cancer 2483 hsa-mir-143 Colorectal Neoplasms 20094072 anti-oncomirs 2484 hsa-mir-17 Toxoplasma 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases 2485 hsa-mir-18a Toxoplasma 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases 2486 hsa-mir-19a Toxoplasma 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases 2487 hsa-mir-19b-1 Toxoplasma 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases 2488 hsa-mir-19b-2 Toxoplasma 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases 2489 hsa-mir-20a Toxoplasma 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases 2490 hsa-mir-106b Toxoplasma 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases 2491 hsa-mir-21 Breast Neoplasms 20082533 Downregulation of miR-21 enhances chemotherapeutic effect of taxol in breast carcinoma cells 2492 hsa-mir-150 Stomach Neoplasms 20067763 MiR-150 promotes gastric cancer proliferation by negatively regulating the pro-apoptotic gene EGR2 2493 hsa-mir-19a Neoplasms 20008935 miR-19 is a key oncogenic component of mir-17-92 2494 hsa-mir-19b-1 Neoplasms 20008935 miR-19 is a key oncogenic component of mir-17-92 2495 hsa-mir-19b-2 Neoplasms 20008935 miR-19 is a key oncogenic component of mir-17-92 2496 hsa-mir-449b Cystitis, Interstitial 20008142 demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels 2497 hsa-mir-500a Cystitis, Interstitial 20008142 demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels 2498 hsa-mir-328 Cystitis, Interstitial 20008142 demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels 2499 hsa-mir-320a Cystitis, Interstitial 20008142 demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels 2500 hsa-mir-320b-1 Cystitis, Interstitial 20008142 demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels 2501 hsa-mir-320b-2 Cystitis, Interstitial 20008142 demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels 2502 hsa-mir-320c-1 Cystitis, Interstitial 20008142 demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels 2503 hsa-mir-320c-2 Cystitis, Interstitial 20008142 demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels 2504 hsa-mir-320d-1 Cystitis, Interstitial 20008142 demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels 2505 hsa-mir-320d-2 Cystitis, Interstitial 20008142 demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels 2506 hsa-mir-206 Synapses 20007902 miR-206 slows ALS progression by sensing motor neuron injury and promoting the compensatory regeneration of neuromuscular synapses 2507 hsa-mir-24-1 Hepatitis C 20006370 miR-24, miR-149, miR-638 and miR-1181 were identified to be involved in HCV entry, replication and propagation 2508 hsa-mir-24-2 Hepatitis C 20006370 miR-24, miR-149, miR-638 and miR-1181 were identified to be involved in HCV entry, replication and propagation 2509 hsa-mir-149 Hepatitis C 20006370 miR-24, miR-149, miR-638 and miR-1181 were identified to be involved in HCV entry, replication and propagation 2510 hsa-mir-638 Hepatitis C 20006370 miR-24, miR-149, miR-638 and miR-1181 were identified to be involved in HCV entry, replication and propagation 2511 hsa-mir-1181 Hepatitis C 20006370 miR-24, miR-149, miR-638 and miR-1181 were identified to be involved in HCV entry, replication and propagation 2512 hsa-let-7g Neoplasms 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras 2513 hsa-let-7a-1 Neoplasms 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras 2514 hsa-let-7a-2 Neoplasms 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras 2515 hsa-let-7f-1 Neoplasms 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras 2516 hsa-let-7d Neoplasms 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras 2517 hsa-let-7i Neoplasms 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras 2518 hsa-let-7c Neoplasms 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras 2519 hsa-let-7b Neoplasms 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras 2520 hsa-let-7f-2 Neoplasms 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras 2521 hsa-let-7a-3 Neoplasms 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras 2522 hsa-let-7e Neoplasms 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras 2523 hsa-mir-132 Inflammation 20005135 MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase 2524 hsa-let-7g Retinoblastoma 20004941 Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. 2525 hsa-let-7a-1 Retinoblastoma 20004941 Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. 2526 hsa-let-7a-2 Retinoblastoma 20004941 Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. 2527 hsa-let-7a-3 Retinoblastoma 20004941 Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. 2528 hsa-let-7d Retinoblastoma 20004941 Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. 2529 hsa-let-7i Retinoblastoma 20004941 Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. 2530 hsa-let-7e Retinoblastoma 20004941 Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. 2531 hsa-let-7c Retinoblastoma 20004941 Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. 2532 hsa-let-7b Retinoblastoma 20004941 Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. 2533 hsa-let-7f-2 Retinoblastoma 20004941 Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. 2534 hsa-let-7f-1 Retinoblastoma 20004941 Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas. 2535 hsa-mir-17 Multiple Sclerosis 20201009 Specifically, miR-17-5p, which is involved in autoimmunity, is upregulated in CD4(+) cells from MS patients 2536 hsa-mir-146a Acute Coronary Syndrome 20195282 miR-146a in PBMCs modulates Th1 function in patients with acute coronary syndrome 2537 hsa-mir-146a Atherosclerosis 20195282 this study also provided evidence that miR-146a treatment in vitro could induce the protein expression of TNF-alpha, MCP-1, NF-kappaB p65, which are key pro-inflammatory cytokines and critical transcription factor in AS 2538 hsa-mir-486 Lung Neoplasms 20194856 levels of four miRNAs (ie, miR-486, miR-30d, miR-1 and miR-499) were significantly associated with overall survival 2539 hsa-mir-30d Lung Neoplasms 20194856 levels of four miRNAs (ie, miR-486, miR-30d, miR-1 and miR-499) were significantly associated with overall survival 2540 hsa-mir-499a Lung Neoplasms 20194856 levels of four miRNAs (ie, miR-486, miR-30d, miR-1 and miR-499) were significantly associated with overall survival 2541 hsa-mir-126 Myocardial Infarction 20187981 we found that AMI is associated with altered miRNA expression level and the differentially expressed miRNAs may be novel biomarkers of AMI 2542 hsa-mir-499a Myocardial Infarction 20187981 miR-499-5p; we found that AMI is associated with altered miRNA expression level and the differentially expressed miRNAs may be novel biomarkers of AMI 2543 hsa-mir-31 Myocardial Infarction 20187981 we found that AMI is associated with altered miRNA expression level and the differentially expressed miRNAs may be novel biomarkers of AMI 2544 hsa-mir-210 Carcinoma, Squamous Cell 20187102 Expression of hsa-miR-210 in head and neck cancer correlates with other approaches for assessing hypoxia and is associated with prognosis 2545 hsa-mir-34a Metabolic Diseases 20185821 Our study demonstrates an unexpected role of the FXR/SHP pathway in controlling SIRT1 levels via miR-34a inhibition and that elevated miR-34a levels in obese mice contribute to decreased SIRT1 levels 2546 hsa-mir-34a Neoplasms 20185821 Our study demonstrates an unexpected role of the FXR/SHP pathway in controlling SIRT1 levels via miR-34a inhibition and that elevated miR-34a levels in obese mice contribute to decreased SIRT1 levels 2547 hsa-mir-31 Neoplasms 20179198 miR-31 is associated with defects in the p53 pathway and functions in serous ovarian cancer and other cancers 2548 hsa-mir-31 Ovarian Neoplasms 20179198 miR-31 is associated with defects in the p53 pathway and functions in serous ovarian cancer and other cancers 2549 hsa-mir-208a Myocardial Infarction 20159880 Elevated cardiac-specific miR-208a in plasma may be a novel biomarker for early detection of myocardial injury in humans 2550 hsa-mir-195 Schizophrenia 20156358 EGR3 and hsa-miR-195 were core regulators 2551 hsa-mir-21 Carcinoma, Squamous Cell 20145181 overexpression 2552 hsa-mir-155 Carcinoma, Squamous Cell 20145181 overexpression 2553 hsa-let-7i Carcinoma, Squamous Cell 20145181 overexpression 2554 hsa-mir-142 Carcinoma, Squamous Cell 20145181 miR-142-3p; overexpression 2555 hsa-mir-375 Carcinoma, Squamous Cell 20145181 underexpression 2556 hsa-mir-423 Carcinoma, Squamous Cell 20145181 Upregulation 2557 hsa-mir-106b Carcinoma, Squamous Cell 20145181 Upregulation 2558 hsa-mir-20a Carcinoma, Squamous Cell 20145181 Upregulation 2559 hsa-mir-10a Carcinoma, Squamous Cell 20145181 downregulation 2560 hsa-mir-195 Breast Neoplasms 20134314 circulating levels of miR-195 and let-7a decreased in cancer patients postoperatively 2561 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 20129242 miR-15a and miR-16-1 were the first microRNAs linked to cancer because their genes are commonly deleted in human chronic lymphocytic leukemia (CLL) 2562 hsa-mir-200a Uterine Cervical Neoplasms 20124485 play important regulatory roles in cervical cancer control 2563 hsa-mir-222 Carcinoma, Hepatocellular 20103675 overexpression 2564 hsa-mir-21 Prostatic Neoplasms 20092645 oncogenic properties of miR-21 could be cell and tissue dependent 2565 hsa-mir-34a Leukemia, Lymphocytic, Chronic, B-Cell 20089965 overexpression of miR-34a in primary B-CLL cells induced apoptosis 2566 hsa-mir-18a Neuroblastoma 20080637 miR-18a and miR-19a target and repress the expression of estrogen receptor-alpha (ESR1) 2567 hsa-mir-19a Neuroblastoma 20080637 miR-18a and miR-19a target and repress the expression of estrogen receptor-alpha (ESR1) 2568 hsa-mir-150 Myocardial Infarction 20075508 dysregulation 2569 hsa-mir-186 Myocardial Infarction 20075508 dysregulation 2570 hsa-mir-210 Myocardial Infarction 20075508 dysregulation 2571 hsa-mir-451a Myocardial Infarction 20075508 dysregulation 2572 hsa-mir-133b Myocardial Infarction 20075508 dysregulation 2573 hsa-mir-125a Retinal Degeneration 20053268 Over-expression 2574 hsa-mir-204 Retinal Degeneration 20053268 Over-expression 2575 hsa-mir-155 Francisella 20041145 However, impaired miR-155 induction by SCHU S4 may help explain the lack of both SHIP down-regulation and pro-inflammatory response and may account for the virulence of Type A Francisella 2576 hsa-mir-133b Myocardial Infarction 20029200 downregulated 2577 hsa-mir-100 Stomach Neoplasms 20022810 progression-related signature, miR-125b, miR-199a, and miR-100 were the most important microRNAs involved 2578 hsa-let-7g Stomach Neoplasms 20022810 low expression 2579 hsa-mir-214 Stomach Neoplasms 20022810 high expression 2580 hsa-mir-433 Stomach Neoplasms 20022810 Low expression 2581 hsa-mir-21 Carcinoma, Hepatocellular 20018759 A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC 2582 hsa-mir-222 Carcinoma, Hepatocellular 20018759 A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC 2583 hsa-mir-34a Carcinoma, Hepatocellular 20018759 A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC 2584 hsa-mir-93 Carcinoma, Hepatocellular 20018759 A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC 2585 hsa-mir-96 Carcinoma, Hepatocellular 20018759 A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC 2586 hsa-let-7c Carcinoma, Hepatocellular 20018759 A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC 2587 hsa-mir-146a Chlamydia Infections 20011700 microRNA-146a is a negative regulator of Tolllike receptor (TLR) signaling 2588 hsa-mir-206 Amyotrophic Lateral Sclerosis 20007902 MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice 2589 hsa-mir-31 Schistosomiasis 19997615 some nucleotides at many positions of Schistosoma miRNAs, such as miR-8, let-7, miR-10, miR-31, miR-92, miR-124, and miR-125, are indeed significantly distinct from other bilaterian orthologs 2590 hsa-mir-21 Cryptosporidium 19997496 mir-125b-1, mir-21, mir-30b, and mir-23b-27b-24-1 cluster genes were transactivated through promoter binding of the NF-kappaB p65 subunit following C. parvum infection 2591 hsa-mir-30b Cryptosporidium 19997496 mir-125b-1, mir-21, mir-30b, and mir-23b-27b-24-1 cluster genes were transactivated through promoter binding of the NF-kappaB p65 subunit following C. parvum infection 2592 hsa-mir-23b Cryptosporidium 19997496 mir-125b-1, mir-21, mir-30b, and mir-23b-27b-24-1 cluster genes were transactivated through promoter binding of the NF-kappaB p65 subunit following C. parvum infection 2593 hsa-mir-27b Cryptosporidium 19997496 mir-125b-1, mir-21, mir-30b, and mir-23b-27b-24-1 cluster genes were transactivated through promoter binding of the NF-kappaB p65 subunit following C. parvum infection 2594 hsa-mir-126 Atherosclerosis 19996457 Administration of apoptotic bodies or miR-126 limited atherosclerosis 2595 hsa-mir-145 Prostatic Neoplasms 19996289 miR-145 and miR-331-3p are predicted to target 3 of the 20 hub genes 2596 hsa-mir-331 Prostatic Neoplasms 19996289 miR-145 and miR-331-3p are predicted to target 3 of the 20 hub genes 2597 hsa-mir-195 Adrenocortical Adenoma 19996210 miR-335 and miR-195 were significantly downregulated in adrenocortical carcinomas 2598 hsa-mir-483 Adrenocortical Adenoma 19996210 miR-335 and miR-195 were significantly downregulated in adrenocortical carcinomas 2599 hsa-mir-122 Hepatitis C, Chronic 19965718 a locked nucleic acid (LNA)-modified oligonucleotide (SPC3649) complementary to miR-122 leads to long-lasting suppression of HCV viremia 2600 hsa-mir-17 Lymphoma 19933089 miR-17-5p can induce tumorigenesis, such as lymphoma and vascularized tumor as an oncogene 2601 hsa-mir-17 Lymphoma 19933089 miR-17-3p can induce tumorigenesis, such as lymphoma and vascularized tumor as an oncogene 2602 hsa-mir-18a Lymphoma 19933089 it can induce tumorigenesis, such as lymphoma and vascularized tumor as an oncogene 2603 hsa-mir-19a Lymphoma 19933089 it can induce tumorigenesis, such as lymphoma and vascularized tumor as an oncogene 2604 hsa-mir-20a Lymphoma 19933089 it can induce tumorigenesis, such as lymphoma and vascularized tumor as an oncogene 2605 hsa-mir-25 Endomyocardial Fibrosis 19919989 both miR-25 and miR-29a were sufficient to decrease collagen gene expression 2606 hsa-mir-29a Endomyocardial Fibrosis 19919989 both miR-25 and miR-29a were sufficient to decrease collagen gene expression 2607 hsa-mir-126 Vascular Diseases 19917099 miR-126, miR-24 and miR-23a are selectively expressed in microvascular endothelial cells in vivo 2608 hsa-mir-23a Vascular Diseases 19917099 miR-126, miR-24 and miR-23a are selectively expressed in microvascular endothelial cells in vivo 2609 hsa-mir-145 Vascular Diseases 19917099 elevated levels of miR-145 reduced migration of microvascular cells in response to growth factor gradients in vitro 2610 hsa-mir-17 SARS Virus 19915717 Upregulated BASC miRNAs-17*, -574-5p, and -214 are co-opted by SARS-CoV to suppress its own replication and evade immune elimination 2611 hsa-mir-574 SARS Virus 19915717 Upregulated BASC miRNAs-17*, -574-5p, and -214 are co-opted by SARS-CoV to suppress its own replication and evade immune elimination 2612 hsa-mir-214 SARS Virus 19915717 Upregulated BASC miRNAs-17*, -574-5p, and -214 are co-opted by SARS-CoV to suppress its own replication and evade immune elimination 2613 hsa-mir-200a Nephrosclerosis 19910931 significantly higher in patients with hypertensive nephrosclerosis than controls 2614 hsa-mir-200b Nephrosclerosis 19910931 significantly higher in patients with hypertensive nephrosclerosis than controls 2615 hsa-mir-141 Nephrosclerosis 19910931 significantly higher in patients with hypertensive nephrosclerosis than controls 2616 hsa-mir-429 Nephrosclerosis 19910931 significantly higher in patients with hypertensive nephrosclerosis than controls 2617 hsa-mir-205 Nephrosclerosis 19910931 significantly higher in patients with hypertensive nephrosclerosis than controls 2618 hsa-mir-192 Nephrosclerosis 19910931 significantly higher in patients with hypertensive nephrosclerosis than controls 2619 hsa-mir-10b Adenocarcinoma 19891660 down-regulated 2620 hsa-mir-152 Adenocarcinoma 19891660 down-regulated 2621 hsa-mir-200a Adenocarcinoma 19891660 up-regulated 2622 hsa-mir-200b Adenocarcinoma 19891660 up-regulated 2623 hsa-mir-205 Adenocarcinoma 19891660 up-regulated 2624 hsa-mir-17 Neoplasms 19887902 miR-17-5p has initially been linked to tumorigenesis 2625 hsa-mir-17 Neoplasms 19887902 miR-17-3p has initially been linked to tumorigenesis 2626 hsa-mir-18a Neoplasms 19887902 has initially been linked to tumorigenesis 2627 hsa-mir-19a Neoplasms 19887902 has initially been linked to tumorigenesis 2628 hsa-mir-20a Neoplasms 19887902 has initially been linked to tumorigenesis 2629 hsa-mir-193b Hematologic Neoplasms 19883314 miR-193b-365 significantly up-regulated in MM 2630 hsa-mir-222 Leukemia, Myeloid, Acute 19883312 miR-222 ( p = 0.0023) and miR-181a ( p = 0.014) expression was higher in AML than in MDS 2631 hsa-mir-15a Leukemia, Myeloid, Acute 19883312 miR-15a in BM ( p = 0.034) and miR-16 in PB ( p = 0.005) were differentially expressed between low-risk and high-risk groups 2632 hsa-mir-125a Ovarian Neoplasms 19881956 Overexpression of miR-125a induces conversion of highly invasive ovarian cancer cells 2633 hsa-mir-125a Breast Neoplasms 19875930 MicroRNA-125a represses cell growth by targeting HuR in breast cancer 2634 hsa-mir-200b Adrenal Cortex Neoplasms 19849700 down-regulated 2635 hsa-mir-203 Adrenal Cortex Neoplasms 19849700 down-regulated 2636 hsa-mir-210 Adrenal Cortex Neoplasms 19849700 up-regulated 2637 hsa-mir-484 Adrenal Cortex Neoplasms 19849700 up-regulated 2638 hsa-mir-126 Asthma 19843690 Selective blockade of microRNA (miR)-126 suppressed the asthmatic phenotype 2639 hsa-mir-326 Multiple Sclerosis 19838199 miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis 2640 hsa-let-7g Lung Neoplasms 19745602 let-7g was down-regulated in radio-resistant H1299 cells, 2641 hsa-mir-122 Stroke 19745058 tissue-specific miRNAs may serve as diagnostically sensitive plasma biomarkers of tissue injury 2642 hsa-mir-100 Nasopharyngeal Neoplasms 19739117 under-expressed miR-100 leads to Plk1 (Polo-like kinase 1) over-expression 2643 hsa-mir-21 Prostatic Neoplasms 19738047 may contribute to CaP 2644 hsa-mir-500a Carcinoma, Hepatocellular 19737067 miR-500 is an oncofetal miRNA relevant to the diagnosis of human HCC 2645 hsa-mir-34a Lung Neoplasms 19736307 miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer 2646 hsa-mir-140 Osteosarcoma 19734943 involved in chemoresistance 2647 hsa-mir-140 Colonic Neoplasms 19734943 involved in chemoresistance 2648 hsa-mir-21 Adenocarcinoma 19730150 microRNA-21 or -221 arrests cell cycle, induces apoptosis,and sensitizes the effects of gemcitabine in pancreatic adenocarcinoma 2649 hsa-mir-221 Adenocarcinoma 19730150 microRNA-21 or -221 arrests cell cycle, induces apoptosis,and sensitizes the effects of gemcitabine in pancreatic adenocarcinoma 2650 hsa-mir-208a Cardiomegaly 19726871 MicroRNA-208a is a regulator of cardiac hypertrophy 2651 hsa-mir-122 Carcinoma, Hepatocellular 19726678 inhibit and sensitizes cancer cells to Sorafenib 2652 hsa-mir-155 Stroke 19724284 correlate(pregulated or downregulated) 2653 hsa-mir-362 Stroke 19724284 miR-362-3p correlate(pregulated or downregulated) 2654 hsa-mir-298 Stroke 19724284 correlate(pregulated or downregulated) 2655 hsa-mir-21 Adenocarcinoma 19723895 proven or predicted target 2656 hsa-mir-210 Adenocarcinoma 19723895 proven or predicted target 2657 hsa-mir-155 Adenocarcinoma 19723895 uperegulated 2658 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 19723889 cell cycle regulation 2659 hsa-mir-206 Neoplasms 19723635 inhibits Notch3 2660 hsa-mir-210 Ischemic Preconditioning 19721136 promoted MSCs survival 2661 hsa-mir-143 Wounds and Injuries 19720868 modulate cytoskeletal dynamics and responsiveness 2662 hsa-mir-145 Wounds and Injuries 19720868 modulate cytoskeletal dynamics and responsiveness 2663 hsa-mir-223 Leukemia, Lymphocytic, Chronic, B-Cell 19717645 strongly associated with disease progression 2664 hsa-mir-29c Leukemia, Lymphocytic, Chronic, B-Cell 19717645 strongly associated with disease progression 2665 hsa-mir-15a Arthritis, Psoriatic 19714650 suppresses apoptosis through inhibition of Bcl-2 2666 hsa-mir-140 Osteoarthritis 19714579 down-regulated IL-1beta-induced ADAMTS5 2667 hsa-mir-342 Prion Diseases 19712440 miR-342-3p; upregulated 2668 hsa-mir-155 Carcinoma, Hepatocellular 19711427 up-regulated 2669 hsa-mir-221 Carcinoma, Hepatocellular 19711427 up-regulated 2670 hsa-mir-222 Carcinoma, Hepatocellular 19711427 up-regulated 2671 hsa-mir-21 Carcinoma, Hepatocellular 19711427 up-regulated 2672 hsa-mir-206 Rhabdomyosarcoma 19710019 MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development 2673 hsa-mir-18a Neoplasms 19706389 significantly upregulated, downregulate Eralpha 2674 hsa-mir-200a Meningioma 19703647 down-regulation promotes tumor growth 2675 hsa-let-7d Cocaine-Related Disorders 19703567 downregulated 2676 hsa-mir-155 Stomach Neoplasms 19702585 possible role in the intimate relationship 2677 hsa-mir-21 Stomach Neoplasms 19702585 possible role in the intimate relationship 2678 hsa-mir-27a Stomach Neoplasms 19702585 possible role in the intimate relationship 2679 hsa-mir-221 Stomach Neoplasms 19702585 possible role in the intimate relationship 2680 hsa-mir-222 Stomach Neoplasms 19702585 possible role in the intimate relationship 2681 hsa-mir-15a Myelodysplastic Syndromes 19702585 differentially expressed between low-risk and high-risk 2682 hsa-mir-214 Hepatoblastoma 19701500 upregulated 2683 hsa-mir-150 Hepatoblastoma 19701500 upregulated 2684 hsa-mir-125a Hepatoblastoma 19701500 upregulated 2685 hsa-mir-148a Hepatoblastoma 19701500 downregulated 2686 hsa-mir-155 Fibroblasts 19701459 upregulates and target KGF 3'-UTR 2687 hsa-mir-96 Pain 19699278 association with chronic neuropathic pain, mechanical hypersensitivity 2688 hsa-mir-182 Pain 19699278 association with chronic neuropathic pain, mechanical hypersensitivity 2689 hsa-mir-183 Pain 19699278 association with chronic neuropathic pain, mechanical hypersensitivity 2690 hsa-mir-34a Pain 19699278 association with chronic neuropathic pain, mechanical hypersensitivity 2691 hsa-mir-107 Leukemia, Lymphocytic, Chronic, B-Cell 19692702 regulation of PLAG1 by miR-181a, miR-181b, miR-107, and miR-424 2692 hsa-mir-143 Endometriosis 19692421 dysregulation 2693 hsa-mir-145 Vascular Diseases 19690387 MicroRNA-modulated targeting of vascular smooth muscle cells 2694 hsa-mir-17 Vascular Diseases 19690387 miR-17-92 and miR-17-5p/miR-20a; MicroRNA-modulated targeting of vascular smooth muscle cells 2695 hsa-mir-18a Vascular Diseases 19690387 miR-17-92 and miR-17-5p/miR-20a; MicroRNA-modulated targeting of vascular smooth muscle cells 2696 hsa-mir-19a Vascular Diseases 19690387 miR-17-92 and miR-17-5p/miR-20a; MicroRNA-modulated targeting of vascular smooth muscle cells 2697 hsa-mir-20a Vascular Diseases 19690387 miR-17-92 and miR-17-5p/miR-20a; MicroRNA-modulated targeting of vascular smooth muscle cells 2698 hsa-mir-499a Lymphoma 19690137 deregulated, hypermutations 2699 hsa-mir-208b Atrophy 19690046 regulation of β-myosin heavy chain gene 2700 hsa-mir-125a Atrophy 19690046 regulation of β-myosin heavy chain gene 2701 hsa-mir-107 Diabetes Mellitus, Type 2 19689793 over-expressed in insulin target tissues 2702 hsa-mir-185 Lung Neoplasms 19688090 cell cycle arrest 2703 hsa-mir-18a Lung Neoplasms 19688090 cell cycle arrest 2704 hsa-mir-18b Breast Neoplasms 19684618 inhibit Eralpha signaling 2705 hsa-mir-193b Breast Neoplasms 19684618 inhibit Eralpha signaling 2706 hsa-mir-206 Breast Neoplasms 19684618 inhibit Eralpha signaling 2707 hsa-mir-302c Breast Neoplasms 19684618 inhibit Eralpha signaling 2708 hsa-mir-18a Breast Neoplasms 19684618 higher levels of expression in ERalpha-negative tumors 2709 hsa-mir-34a Breast Neoplasms 19684618 higher levels of expression in ERalpha-negative tumors 2710 hsa-mir-21 Alzheimer Disease 19683563 up-regulated, inhibits bcl2 translation 2711 hsa-mir-31 Carcinoma 19676045 down-regulated 2712 hsa-mir-145 Carcinoma 19676045 down-regulated 2713 hsa-mir-149 Carcinoma 19676045 down-regulated 2714 hsa-mir-184 Carcinoma 19676045 down-regulated 2715 hsa-mir-205 Carcinoma 19676045 down-regulated 2716 hsa-mir-221 Carcinoma 19676045 down-regulated 2717 hsa-mir-222 Carcinoma 19676045 down-regulated 2718 hsa-mir-182 Carcinoma 19676045 down-regulated 2719 hsa-mir-183 Carcinoma 19676045 up-regulated 2720 hsa-mir-96 Carcinoma 19676045 up-regulated 2721 hsa-mir-19a Glioblastoma 19676043 inhibite Bcl-2 and Mcl-1, induce apoptosis 2722 hsa-mir-17 Glioblastoma 19676043 inhibite Bcl-2 and Mcl-1, induce apoptosis 2723 hsa-mir-18a Glioblastoma 19676043 inhibite Bcl-2 and Mcl-1, induce apoptosis 2724 hsa-mir-21 Adenocarcinoma 19672269 expression Increased 2725 hsa-mir-221 Cholesteatoma 19672202 up-regulated concurrent with down-regulation of PTEN 2726 hsa-mir-93 Urinary Bladder Neoplasms 19671845 control the EMT process and sensitivity to EGFR therapy 2727 hsa-mir-98 Lung Neoplasms 19671678 regulate tumor suppressor gene FUS1 2728 hsa-mir-197 Lung Neoplasms 19671678 regulate tumor suppressor gene FUS1 2729 hsa-mir-93 Lung Neoplasms 19671678 regulate tumor suppressor gene FUS1 2730 hsa-mir-205 Hodgkin Disease 19666866 Regulates JAK2, prognostic impact 2731 hsa-mir-200c Neoplasms 19665999 inhibits through down-regulating LRP1 2732 hsa-mir-200b Breast Neoplasms 19665978 downregulated, modulate Expression of BMI1, suppressed tumor formation of normal stem cell 2733 hsa-mir-200a Breast Neoplasms 19665978 downregulated in human BCSCs 2734 hsa-mir-429 Breast Neoplasms 19665978 downregulated in human BCSCs 2735 hsa-mir-96 Breast Neoplasms 19665978 downregulated in human BCSCs 2736 hsa-mir-182 Breast Neoplasms 19665978 downregulated in human BCSCs 2737 hsa-mir-183 Breast Neoplasms 19665978 downregulated in human BCSCs 2738 hsa-mir-137 Colonic Neoplasms 19659786 expressed differently, miR-137 upregulated in non-cancerous colonic tissues from colon cancer patients with lymph node metastasis 2739 hsa-mir-133b Pancreatic Neoplasms 19654291 downregulated, Up-regulation leads to the reversal of EMT 2740 hsa-mir-210 Lung Neoplasms 19654003 low expression, targets pro-survival molecules MCL-1 and BCL2L2 2741 hsa-mir-155 Neoplasms 19652553 overexpression, target MYC antagonist MNT 2742 hsa-mir-195 Eclampsia 19642860 increased in placenta 2743 hsa-mir-26b Eclampsia 19642860 increased in placenta 2744 hsa-mir-335 Eclampsia 19642860 increased in placenta 2745 hsa-mir-222 Eclampsia 19642860 increased in placenta 2746 hsa-mir-21 Eclampsia 19642860 increased in placenta 2747 hsa-mir-155 Lymphoma, Extranodal NK-T-Cell 19641183 miR-21 or miR-155 led to down-regulation of PTEN and PDCD4 or SHIP1 with up-regulation of phosphorylated AKT(ser473). 2748 hsa-mir-27a Lymphoma, Extranodal NK-T-Cell 19641183 miR-21 or miR-155 led to down-regulation of PTEN and PDCD4 or SHIP1 with up-regulation of phosphorylated AKT(ser473). 2749 hsa-mir-143 Melanoma 19639204 miR-27a and its target gene ZBTB10 significantly different based on the dose of genistein 2750 hsa-mir-7-1 Parkinson Disease 19628698 expression decreases; miR-7 down-regulates of alpha-expression decreases synuclein, protects cells against oxidative stress 2751 hsa-mir-200b Breast Neoplasms 19624877 Differential expression profiles of microRNAs between breast cancer cells and mammary epithelial cells: mir-18a and mir-195 were highly expressed in MCF-7 cells; target genes of mir-200b were predicted by informatics analysis. 2752 hsa-mir-18a Breast Neoplasms 19624877 Differential expression profiles of microRNAs between breast cancer cells and mammary epithelial cells: mir-18a and mir-195 were highly expressed in MCF-7 cells; target genes of mir-200b were predicted by informatics analysis. 2753 hsa-mir-223 Breast Neoplasms 19624877 Differential expression profiles of microRNAs between breast cancer cells and mammary epithelial cells: mir-18a and mir-195 were highly expressed in MCF-7 cells; target genes of mir-200b were predicted by informatics analysis. 2754 hsa-mir-206 Rhabdomyosarcoma 19620785 miR-1 was barely detectable in primary RMS 2755 hsa-mir-34c Rhabdomyosarcoma 19620785 The muscle-specific microRNA miR-206, blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation 2756 hsa-mir-145 Lung Neoplasms 19618089 miR-34c, miR-145, or miR-142-5p expression markedly diminished proliferation of lung cancer cell lines, clinical implications discussed 2757 hsa-mir-142 Lung Neoplasms 19618089 miR-34c, miR-145, or miR-142-5p expression markedly diminished proliferation of lung cancer cell lines, clinical implications discussed 2758 hsa-mir-18b Lung Neoplasms 19618089 miR-34c, miR-145, or miR-142-5p expression markedly diminished proliferation of lung cancer cell lines, clinical implications discussed 2759 hsa-mir-599 Multiple Sclerosis 19617918 relevant at the time of relapse 2760 hsa-mir-96 Multiple Sclerosis 19617918 relevant at the time of relapse 2761 hsa-mir-122 Multiple Sclerosis 19617918 The genes targeted by hsa-miR-96 are involved inimmunological pathways as Interleukin signaling and in other pathways as wnt signaling 2762 hsa-mir-150 Carcinoma, Hepatocellular 19617899 repressed in a subset of primary tumorscharacterized by poor prognosis; loss of miR-122 expression correlates with suppression of the hepatic phenotype and gain of metastatic properties; a diagnostic and prognostic marker 2763 hsa-mir-222 Myelodysplastic Syndromes 19615744 Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndrome 2764 hsa-mir-221 Myelodysplastic Syndromes 19615744 Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndrome 2765 hsa-mir-125a Myelodysplastic Syndromes 19615744 Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndrome 2766 hsa-mir-31 Leiomyosarcoma 19602040 overexpression; leads to HMGA2 overexpression; Disrupting the control of HMGA2 and let-7 pairs promotes ULMS cell growth in vitro. 2767 hsa-mir-17 Stomach Neoplasms 19598010 miR-17-92a cluster; expression lwere significantly lower than non-cancer tissue; may help to clarify the molecular mechanisms; may be a novel diagnostic biomarker 2768 hsa-mir-19a Stomach Neoplasms 19598010 miR-17-92a cluster; expression lwere significantly lower than non-cancer tissue; may help to clarify the molecular mechanisms; may be a novel diagnostic biomarker 2769 hsa-mir-18a Stomach Neoplasms 19598010 miR-17-92a cluster; expression lwere significantly lower than non-cancer tissue; may help to clarify the molecular mechanisms; may be a novel diagnostic biomarker 2770 hsa-mir-17 Lung Neoplasms 19597473 miR-17-5p ; frequent overexpression 2771 hsa-mir-20a Lung Neoplasms 19597473 miR-17-92 overexpression may serve as a fine-tuning influence to counterbalance the generation of DNA damage 2772 hsa-mir-21 Prostatic Neoplasms 19597470 acts as tumor suppressor and induces apoptosis of tumor cells through E2F1-mediated suppression of Akt phosphorylation 2773 hsa-mir-155 Lung Neoplasms 19597153 down-regulated miR 2774 hsa-mir-10b Myocardial Infarction 19595696 Knockdown of microRNA-181 by lentivirus decreases the arrhythmogenic effect of skeletal myoblast transplantation in rat with myocardial infarction. 2775 hsa-mir-21 Neoplasms 19593777 association with cancer progression 2776 hsa-mir-30a Neoplasms 19593777 association with cancer progression 2777 hsa-mir-30e Neoplasms 19593777 association with cancer progression 2778 hsa-mir-141 Neoplasms 19593777 association with cancer progression 2779 hsa-mir-200b Neoplasms 19593777 association with cancer progression 2780 hsa-mir-200c Neoplasms 19593777 association with cancer progression 2781 hsa-mir-205 Neoplasms 19593777 association with cancer progression 2782 hsa-mir-221 Carcinoma, Hepatocellular 19585654 critical player; up-regulated; could directly target hepatic transcriptional regulators of differentiation and an inhibitor of Wnt/beta-catenin signaling 2783 hsa-mir-122 Neoplasms 19584290 down-regulated; modulates expression of immunoinhibitory molecule B7-H3;directly target B7-H3 3' untranslated region, and knock-in and knockdown of miR-29a led to down-regulation and up-regulation of B7-H3 protein expression; potential immune based therapy 2784 hsa-mir-146b Carcinoma, Hepatocellular 19584283 a liver-specific miRNA; down-regulation in HCC; miR-122 can regulate the expression of cyclin G1; by modulating cyclin G1 with doxorubicin, miR-122 influences p53 protein stability and transcriptional activity and reduces invasion capability of HCC-derived cell lines; miR-122, as well as cyclin G1 silencing, increases sensitivity to doxorubicin challenge; miR-122 levels were associated with a shorter TTR (time to recurrence); potential combined chemo- and miRNA-based therapeutic target 2785 hsa-mir-661 Carcinoma, Squamous Cell 19584273 miR-146b alone have the strongest prediction accuracy for stratifying prognostic groups; 2786 hsa-mir-331 Neoplasms 19584269 miR-331-3p; a c/EBPalpha target,; Inhibits metastatic tumor antigen 1 2787 hsa-mir-27a Prostatic Neoplasms 19584056 decreased in prostate cancer; Regulates ERBB-2 Expression; blocked downstream phosphatidylinositol 3-kinase/AKT signaling, reducing activity of an androgen-stimulated prostate-specific antigen promoter and blocking prostate-specific antigen expression 2788 hsa-mir-155 Myocardial Infarction 19581315 Overexpressed; arrhythmogenic miR-1, contributing to ischaemic arrhythmogenesis stimulated by beta-adrenergic pathway; downregulatied by propranolol together with SRF 2789 hsa-mir-18a Melanoma 19578755 overexpressed 2790 hsa-mir-20a Melanoma 19578755 overexpressed 2791 hsa-mir-17 Melanoma 19578755 miR-17-5p; overexpressed 2792 hsa-mir-146a Melanoma 19578755 overexpressed 2793 hsa-mir-146b Melanoma 19578755 down-regulated 2794 hsa-mir-155 Melanoma 19578755 down-regulated 2795 hsa-mir-122 Melanoma 19578755 down-regulated 2796 hsa-mir-23a Hepatitis C 19578061 virus specific, miR-122-sensitive double-helical switch element in the 5' region--a new mechanism of action of micro-RNAs 2797 hsa-mir-96 Breast Neoplasms 19574223 Coordinate Regulate FOXO1; highly expressed; a novel mechanism of FOXO1 regulation, and targeting of FOXO1 by microRNAs may contribute to transformation or maintenance of an oncogenic state in breast cancer cells 2798 hsa-mir-182 Breast Neoplasms 19574223 Coordinate Regulate FOXO1; highly expressed; a novel mechanism of FOXO1 regulation, and targeting of FOXO1 by microRNAs may contribute to transformation or maintenance of an oncogenic state in breast cancer cells 2799 hsa-mir-31 Breast Neoplasms 19574223 Coordinate Regulate FOXO1; highly expressed; a novel mechanism of FOXO1 regulation, and targeting of FOXO1 by microRNAs may contribute to transformation or maintenance of an oncogenic state in breast cancer cells 2800 hsa-mir-1224 Fatty Liver 19572984 expression increased after Lieber-DeCarli or MCD; 2801 hsa-mir-182 Fatty Liver 19572984 expression increased after Lieber-DeCarli or MCD; 2802 hsa-mir-183 Fatty Liver 19572984 down-regulated after Lieber-DeCarli ; 2803 hsa-mir-200b Adenocarcinoma 19569050 regulate EP300, a metastasis suppressor gene; these miRs are related to reduced EP300 mRNA and protein; 2804 hsa-mir-200c Adenocarcinoma 19569050 regulate EP300, a metastasis suppressor gene; these miRs are related to reduced EP300 mRNA and protein; 2805 hsa-mir-429 Adenocarcinoma 19569050 regulate EP300, a metastasis suppressor gene; these miRs are related to reduced EP300 mRNA and protein; 2806 hsa-mir-29a Breast Neoplasms 19567675 potentially oncogenic role in breast tumorigenesis; significantly associated with decreased breast cancer risk; mutant precursors of miR-196a-2 into breast cancer cells led to less efficient processing of the miRNA precursor to its mature form as well as diminished capacity to regulate target genes, further showed that cell cycle response to mutagen challenge was significantly enhanced; 2807 hsa-mir-21 HIV 19560422 highly abundant; specifically targets the HIV-1 3'UTR region; Inhibiting miR-29a enhanced HIV-1 viral production and infectivity; specific miR-29a-HIV-1 mRNA interactions enhance viral mRNA association with RISC and P body proteins 2808 hsa-mir-155 Glioblastoma 19559015 overexpressed; contributes to tumor resistance to VM-26 chemotherapy; targets LRRFIP1; 2809 hsa-mir-203 Pancreatic Neoplasms 19551852 differentially expressed; associates with poorer survival 2810 hsa-mir-210 Pancreatic Neoplasms 19551852 differentially expressed; associates with poorer survival 2811 hsa-mir-222 Pancreatic Neoplasms 19551852 differentially expressed; associates with poorer survival 2812 hsa-mir-15a Pancreatic Neoplasms 19551852 differentially expressed; associates with poorer survival 2813 hsa-mir-21 Adenoma 19547998 differential expression, with highest expression levels in SSAs; Levels of miR-181b but not miR-21 differed in HPs and normal mucosa; SSAs exhibited both significantly higher miR-181b levels and miR-21 levels; discriminating potential diagnostic value HP from SSA 2814 hsa-mir-184 Carcinoma 19546886 laryngeal carcinoma, upregulated; control of the G1-S phase transition;regulate BTG2, a cell cycle gene 2815 hsa-mir-503 Adrenal Cortex Neoplasms 19546168 significantly higher expressed 2816 hsa-mir-210 Adrenal Cortex Neoplasms 19546168 significantly higher expressed 2817 hsa-mir-214 Adrenal Cortex Neoplasms 19546168 significantly lower expressed 2818 hsa-mir-145 Prostatic Neoplasms 19544444 regulates PDGF-D, which mediate epithelial-mesenchymal transition, adhesion, and invasion, which was associated with the downregulation of ZEB1, ZEB2,and Snail2 expression; 2819 hsa-mir-10b Carcinoma, Squamous Cell 19540661 tumor suppresser; suppressed cell invasion and led to cell cycle arrest and apoptosis; potential theraeutic target 2820 hsa-mir-30a Carcinoma, Squamous Cell 19536617 high expression levels; might play a important role in the development of the cancer 2821 hsa-let-7a-1 Adenocarcinoma 20413677 let-7a:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 2822 hsa-let-7a-1 Asthma 20630862 let-7a:Proinflammatory role for let-7 microRNAS in experimental asthma 2823 hsa-let-7a-1 Carcinoma 20033209 let-7a:The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice 2824 hsa-let-7a-1 Carcinoma 20614490 let-7a:Gastric carcinoma has relatively lower expression of let-7a 2825 hsa-let-7a-1 Carcinoma, Hepatocellular 20347499 hsa-let-7a:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2826 hsa-let-7a-1 Leukemia, Myeloid, Acute 20425795 hsa-let-7a:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 2827 hsa-let-7a-1 Neoplasms 20404092 let-7a:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells 2828 hsa-let-7a-1 Ovarian Neoplasms 20035894 hsa-let-7a:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families 2829 hsa-let-7a-1 Spinal Cord Injuries 20816819 Let-7a:SCI results in increased expression of miR Let-7a and miR16 2830 hsa-let-7a-2 Adenocarcinoma 20413677 let-7a:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 2831 hsa-let-7a-2 Asthma 20630862 let-7a:Proinflammatory role for let-7 microRNAS in experimental asthma 2832 hsa-let-7a-2 Carcinoma 20033209 let-7a:The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice 2833 hsa-let-7a-2 Carcinoma 20614490 let-7a:Gastric carcinoma has relatively lower expression of let-7a 2834 hsa-let-7a-2 Carcinoma, Hepatocellular 20347499 hsa-let-7a:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2835 hsa-let-7a-2 Leukemia, Myeloid, Acute 20425795 hsa-let-7a:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 2836 hsa-let-7a-2 Neoplasms 20404092 let-7a:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells 2837 hsa-let-7a-2 Ovarian Neoplasms 20035894 hsa-let-7a:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families 2838 hsa-let-7a-2 Spinal Cord Injuries 20816819 Let-7a:SCI results in increased expression of miR Let-7a and miR16 2839 hsa-let-7a-3 Adenocarcinoma 20413677 let-7a:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 2840 hsa-let-7a-3 Asthma 20630862 let-7a:Proinflammatory role for let-7 microRNAS in experimental asthma 2841 hsa-let-7a-3 Carcinoma 20033209 let-7a:The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice 2842 hsa-let-7a-3 Carcinoma 20614490 let-7a:Gastric carcinoma has relatively lower expression of let-7a 2843 hsa-let-7a-3 Carcinoma, Hepatocellular 20347499 hsa-let-7a:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2844 hsa-let-7a-3 Leukemia, Myeloid, Acute 20425795 hsa-let-7a:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 2845 hsa-let-7a-3 Neoplasms 20404092 let-7a:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells 2846 hsa-let-7a-3 Ovarian Neoplasms 20035894 hsa-let-7a:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families 2847 hsa-let-7a-3 Spinal Cord Injuries 20816819 Let-7a:SCI results in increased expression of miR Let-7a and miR16 2848 hsa-let-7b Asthma 20630862 let-7b:Proinflammatory role for let-7 microRNAS in experimental asthma 2849 hsa-let-7b Carcinoma, Hepatocellular 20347499 hsa-let-7b:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2850 hsa-let-7b Leukemia, Myeloid, Acute 20425795 hsa-let-7b:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 2851 hsa-let-7b Mouth Neoplasms 20232482 let-7b:elevated expression levels of Dicer in oral cancer cells correlate with downregulation of let-7b and increased cell proliferation. 2852 hsa-let-7b Ovarian Neoplasms 20035894 hsa-let-7b:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families 2853 hsa-let-7c Asthma 20630862 let-7c:Proinflammatory role for let-7 microRNAS in experimental asthma 2854 hsa-let-7c Carcinoma, Hepatocellular 20347499 hsa-let-7c:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2855 hsa-let-7c Leukemia, Myeloid, Acute 20425795 hsa-let-7c:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 2856 hsa-let-7c Ovarian Neoplasms 20035894 hsa-let-7c:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families 2857 hsa-let-7d Asthma 20630862 let-7d:Proinflammatory role for let-7 microRNAS in experimental asthma 2858 hsa-let-7d Carcinoma, Hepatocellular 20347499 hsa-let-7d:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2859 hsa-let-7d Leukemia, Myeloid, Acute 20425795 hsa-let-7d:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 2860 hsa-let-7d Melanoma 20529253 let-7d:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 2861 hsa-let-7d Ovarian Neoplasms 20035894 hsa-let-7d:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families 2862 hsa-let-7e Adenoviridae Infections 20634878 let-7e:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2863 hsa-let-7e Asthma 20630862 let-7e:Proinflammatory role for let-7 microRNAS in experimental asthma 2864 hsa-let-7e Carcinoma, Hepatocellular 20347499 hsa-let-7e:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2865 hsa-let-7e Leukemia, Myeloid, Acute 20425795 hsa-let-7e:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 2866 hsa-let-7e Ovarian Neoplasms 20035894 hsa-let-7e:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families 2867 hsa-let-7f-1 Asthma 20630862 let-7f:Proinflammatory role for let-7 microRNAS in experimental asthma 2868 hsa-let-7f-1 Carcinoma, Hepatocellular 20347499 hsa-let-7f:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2869 hsa-let-7f-1 Leukemia, Myeloid, Acute 20425795 hsa-let-7f:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 2870 hsa-let-7f-1 Ovarian Neoplasms 20035894 hsa-let-7f:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families 2871 hsa-let-7f-2 Asthma 20630862 let-7f:Proinflammatory role for let-7 microRNAS in experimental asthma 2872 hsa-let-7f-2 Carcinoma, Hepatocellular 20347499 hsa-let-7f:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2873 hsa-let-7f-2 Leukemia, Myeloid, Acute 20425795 hsa-let-7f:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 2874 hsa-let-7f-2 Ovarian Neoplasms 20035894 hsa-let-7f:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families 2875 hsa-let-7g Asthma 20630862 let-7g:Proinflammatory role for let-7 microRNAS in experimental asthma 2876 hsa-let-7g Carcinoma, Hepatocellular 20338660 let-7g:Let-7g targets collagen type I alpha2 and inhibits cell migration in hepatocellular carcinoma 2877 hsa-let-7g Carcinoma, Hepatocellular 20347499 hsa-let-7g:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2878 hsa-let-7g Leukemia, Myeloid, Acute 20425795 hsa-let-7g:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 2879 hsa-let-7g Ovarian Neoplasms 20035894 hsa-let-7g:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families 2880 hsa-let-7i Asthma 20630862 let-7i:Proinflammatory role for let-7 microRNAS in experimental asthma 2881 hsa-let-7i Carcinoma, Hepatocellular 20347499 hsa-let-7i:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 2882 hsa-let-7i Carcinoma, Squamous Cell 20620595 let-7i:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC 2883 hsa-let-7i Leukemia, Myeloid, Acute 20425795 hsa-let-7i:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 2884 hsa-let-7i Melanoma 20529253 let-7i*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 2885 hsa-let-7i Neoplasms 20404092 let-7i:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells 2886 hsa-let-7i Ovarian Neoplasms 20035894 hsa-let-7i:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families 2887 hsa-mir-100 Adrenal Cortex Neoplasms 20484036 miR-100:differentially regulated in childhood adrenocortical tumors (ACT), including miR-99a and miR-100 2888 hsa-mir-100 Nasopharyngeal Neoplasms 19739117 miR-100:miR-100 can directly target Plk1 2889 hsa-mir-101-1 Adenoviridae Infections 20634878 miR-101-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2890 hsa-mir-101-1 Carcinoma, Hepatocellular 20444294 miR-101:PKCalpha mediated induction of miR-101 in human hepatoma HepG2 cells 2891 hsa-mir-101-1 Carcinoma, Squamous Cell 20620595 miR-101:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC 2892 hsa-mir-101-1 Lymphoma, Large-Cell, Anaplastic 20805506 miR-101:miR-101 was down-regulated in all ALCL model systems 2893 hsa-mir-101-1 Neoplasms 20586854 miR-101:Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation 2894 hsa-mir-101-1 Prostatic Neoplasms 20478051 miR-101:miR-101 introduction is a potential therapeutic strategy to combat PCa 2895 hsa-mir-101-2 Adenoviridae Infections 20634878 miR-101-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2896 hsa-mir-101-2 Carcinoma, Hepatocellular 20444294 miR-101:PKCalpha mediated induction of miR-101 in human hepatoma HepG2 cells 2897 hsa-mir-101-2 Carcinoma, Squamous Cell 20620595 miR-101:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC 2898 hsa-mir-101-2 Lymphoma, Large-Cell, Anaplastic 20805506 miR-101:miR-101 was down-regulated in all ALCL model systems 2899 hsa-mir-101-2 Neoplasms 20586854 miR-101:Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation 2900 hsa-mir-101-2 Prostatic Neoplasms 20478051 miR-101:miR-101 introduction is a potential therapeutic strategy to combat PCa 2901 hsa-mir-103a-1 Breast Neoplasms 20603000 miR-103:In human breast cancer, high levels of miR-103/107 are associated with metastasis and poor outcome 2902 hsa-mir-103a-1 Lung Neoplasms 20624269 miR-103:we found significant overexpression of miR-103, miR-107, miR-301 and miR-338 in lung cancer cells as compared to HBECs 2903 hsa-mir-103a-1 Neoplasms 20439436 miR-103:hsa-miR-103/106 were downgraded in cancer, whereas hsa-miR-30 became most prominent 2904 hsa-mir-103a-2 Breast Neoplasms 20603000 miR-103:In human breast cancer, high levels of miR-103/107 are associated with metastasis and poor outcome 2905 hsa-mir-103a-2 Lung Neoplasms 20624269 miR-103:we found significant overexpression of miR-103, miR-107, miR-301 and miR-338 in lung cancer cells as compared to HBECs 2906 hsa-mir-103a-2 Neoplasms 20439436 miR-103:hsa-miR-103/106 were downgraded in cancer, whereas hsa-miR-30 became most prominent 2907 hsa-mir-106a Astrocytoma 20219352 miR-106a:hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma 2908 hsa-mir-106a Neoplasms 20049626 miR-106:miR-16, miR-17, miR-34a-c, and miR-125 served as tumor suppressor miRNAs, while miR-20, miR-106, and miR-150 acted as oncogenic miRNAs 2909 hsa-mir-106a Neoplasms 20049626 miR-106:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 2910 hsa-mir-106a Neoplasms 20439436 miR-106:hsa-miR-103/106 were downgraded in cancer, whereas hsa-miR-30 became most prominent 2911 hsa-mir-106a Stomach Neoplasms 20349219 miR-106a:detection of miRNA in peripheral blood may be a novel tool for monitoring circulating tumor cells in patients with gastric cancers 2912 hsa-mir-106a Toxoplasmosis 20423977 hsa-mir-106a:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii 2913 hsa-mir-106b Carcinoma, Renal Cell 20609231 miRNA-106b:Expression of miRNA-106b in conventional renal cell carcinoma is a potential marker for prediction of early metastasis after nephrectomy 2914 hsa-mir-106b Melanoma 20529253 miR-106b:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 2915 hsa-mir-106b Neoplasms 20404092 mir-106b-25:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells 2916 hsa-mir-106b Toxoplasmosis 20423977 hsa-mir-106b:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii 2917 hsa-mir-107 Breast Neoplasms 20603000 miR-107:In human breast cancer, high levels of miR-103/107 are associated with metastasis and poor outcome 2918 hsa-mir-107 Lung Neoplasms 20624269 miR-107:we found significant overexpression of miR-103, miR-107, miR-301 and miR-338 in lung cancer cells as compared to HBECs 2919 hsa-mir-107 Melanoma 20529253 miR-107:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 2920 hsa-mir-10a Atherosclerosis 20624982 miR-10a:miR-10a contributes to the regulation of proinflammatory endothelial phenotypes in athero-susceptible regions in vivo 2921 hsa-mir-10a Breast Neoplasms 20099276 miR-10a:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c 2922 hsa-mir-10a Glioblastoma 20444541 miR-10a:miR-195, miR-455-3p and miR-10a( *) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells 2923 hsa-mir-10b Carcinoma 20444703 miR-10b:miR-10b targets Tiam1: implications for Rac activation and carcinoma migration 2924 hsa-mir-1-1 Chordoma 20041488 miR-1:miRNA-1 may have a functional effect on chordoma tumor pathogenesis 2925 hsa-mir-1-1 Distal Myopathies 20619221 miR-1:have a profound influence on multiple myopathies 2926 hsa-mir-1-1 Hypertrophy 20619221 miR-1:have a profound influence on multiple myopathies 2927 hsa-mir-1-1 Myelodysplastic Syndromes 20627384 miR-1:Evaluation in a larger cohort could confirm the up-regulation of the miR-1 in MDS 2928 hsa-mir-1-1 Rhabdomyosarcoma 20466878 miR-1:mRNA targets of miR-1 and miR-133a are up-regulated in rhabdomyosarcomas 2929 hsa-mir-1180 Adenoviridae Infections 20634878 hsa-miR-1180:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2930 hsa-mir-1184-1 Adenoviridae Infections 20634878 miR-1184:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2931 hsa-mir-1-2 Chordoma 20041488 miR-1:miRNA-1 may have a functional effect on chordoma tumor pathogenesis 2932 hsa-mir-1-2 Distal Myopathies 20619221 miR-1:have a profound influence on multiple myopathies 2933 hsa-mir-1-2 Hypertrophy 20619221 miR-1:have a profound influence on multiple myopathies 2934 hsa-mir-1-2 Myelodysplastic Syndromes 20627384 miR-1:Evaluation in a larger cohort could confirm the up-regulation of the miR-1 in MDS 2935 hsa-mir-1-2 Rhabdomyosarcoma 20466878 miR-1:mRNA targets of miR-1 and miR-133a are up-regulated in rhabdomyosarcomas 2936 hsa-mir-122 Carcinoma, Hepatocellular 20527935 miR-122:Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma 2937 hsa-mir-122 Carcinoma, Hepatocellular 20859956 miR-122a:microRNA-122a (miR-122a) is a liver-specific miRNA that is frequently downregulated in hepatocellular carcinoma (HCC) 2938 hsa-mir-122 Hepatitis C 20527935 miR-122:Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma 2939 hsa-mir-1224 Lupus Nephritis 20485490 miR-1224-3P:hsa-miR-371-5P, hsa-miR-423-5P, hsa-miR-638, hsa-miR-1224-3P and hsa-miR-663 that were differentially expressed in lupus nephritis across different racial groups and all specimen types tested 2940 hsa-mir-124-1 Carcinoma, Hepatocellular 19843643 miR-124:miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. 2941 hsa-mir-124-1 Myelodysplastic Syndromes 20448201 miRNA-124:Methylation and silencing of miRNA-124 by EVI1 and self-renewal exhaustion of hematopoietic stem cells in murine myelodysplastic syndrome 2942 hsa-mir-124-2 Carcinoma, Hepatocellular 19843643 miR-124:miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. 2943 hsa-mir-124-2 Myelodysplastic Syndromes 20448201 miRNA-124:Methylation and silencing of miRNA-124 by EVI1 and self-renewal exhaustion of hematopoietic stem cells in murine myelodysplastic syndrome 2944 hsa-mir-124-3 Carcinoma, Hepatocellular 19843643 miR-124:miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. 2945 hsa-mir-124-3 Myelodysplastic Syndromes 20448201 miRNA-124:Methylation and silencing of miRNA-124 by EVI1 and self-renewal exhaustion of hematopoietic stem cells in murine myelodysplastic syndrome 2946 hsa-mir-1246 Adenoviridae Infections 20634878 miR-1246:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2947 hsa-mir-1247 Adenoviridae Infections 20634878 miR-1247:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2948 hsa-mir-1249 Melanoma 20529253 miR-1249:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 2949 hsa-mir-125a Carcinoma, Non-Small-Cell Lung 20569443 miR-125a-3p:Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer 2950 hsa-mir-125a Carcinoma, Non-Small-Cell Lung 20569443 miR-125a-5p:Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer 2951 hsa-mir-125a Carcinoma, Squamous Cell 20620595 miR-125a-5p:The miRNAs miR-185 * and miR-125a-5p were significantly upregulated in lung SCC 2952 hsa-mir-125a Melanoma 20529253 miR-125a-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 2953 hsa-mir-125a Neoplasms 20049626 miR-125:miR-16, miR-17, miR-34a-c, and miR-125 served as tumor suppressor miRNAs, while miR-20, miR-106, and miR-150 acted as oncogenic miRNAs 2954 hsa-mir-125a Neoplasms 20049626 miR-125:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 2955 hsa-mir-125b-1 Adenoviridae Infections 20634878 miR-125b-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2956 hsa-mir-125b-1 Breast Neoplasms 20460378 MicroRNA-125b:MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression 2957 hsa-mir-125b-1 Cardiomyopathy, Hypertrophic 20470752 miR-125b:miR-23a, miR-27b, miR-125b and miR-195 were induced during early hypertrophic growth 2958 hsa-mir-125b-1 Leukemia, Biphenotypic, Acute 20485370 miR-125b-1:A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia 2959 hsa-mir-125b-1 Leukemia, Myeloid 20660734 miR-125b:Overexpression of the most advantageous miRNA, miR-125b, caused a dose-dependent myeloproliferative disorder that progressed to a lethal myeloid leukemia in mice 2960 hsa-mir-125b-1 Melanoma 20153427 miR-125b:miRNA125b may be involved in the regulation of VDR expression and in the resistance against 1,25(OH)(2)D(3) in melanoma cells 2961 hsa-mir-125b-1 Neoplasms 20144731 miR-125b:in macrophages, miR-125b, miR-146, and miR-155 act as Pathogen Associated Molecular Pattern Molecule-associated microRNAs 2962 hsa-mir-125b-2 Adenoviridae Infections 20634878 miR-125b-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2963 hsa-mir-125b-2 Breast Neoplasms 20460378 MicroRNA-125b:MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression 2964 hsa-mir-125b-2 Cardiomyopathy, Hypertrophic 20470752 miR-125b:miR-23a, miR-27b, miR-125b and miR-195 were induced during early hypertrophic growth 2965 hsa-mir-125b-2 Leukemia, Myeloid 20660734 miR-125b:Overexpression of the most advantageous miRNA, miR-125b, caused a dose-dependent myeloproliferative disorder that progressed to a lethal myeloid leukemia in mice 2966 hsa-mir-125b-2 Melanoma 20153427 miR-125b:miRNA125b may be involved in the regulation of VDR expression and in the resistance against 1,25(OH)(2)D(3) in melanoma cells 2967 hsa-mir-125b-2 Neoplasms 20144731 miR-125b:in macrophages, miR-125b, miR-146, and miR-155 act as Pathogen Associated Molecular Pattern Molecule-associated microRNAs 2968 hsa-mir-126 Atherosclerosis 20489169 miR-126:found high levels of expression for all of them in quiescent endothelial cells 2969 hsa-mir-126 Carcinoma, Hepatocellular 20619223 miR-126:hsa-miR-126 showed higher expression levels in hepatocellular carcinomas 2970 hsa-mir-126 Carcinoma, Squamous Cell 20620595 miR-126:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC 2971 hsa-mir-126 Colonic Neoplasms 20859756 miR-126:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 2972 hsa-mir-126 Leukemia, Myeloid, Acute 20425795 miR-126:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 2973 hsa-mir-126 Precursor Cell Lymphoblastic Leukemia-Lymphoma 20621067 miR-126:Alteration of processing induced by a single nucleotide polymorphism in pri-miR-126 2974 hsa-mir-126 Stomach Neoplasms 20619534 miR-126:miR-126 functions as a tumour suppressor in human gastric cancer 2975 hsa-mir-1273a Adenoviridae Infections 20634878 miR-1273:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2976 hsa-mir-1280 Melanoma 20529253 miR-1280:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 2977 hsa-mir-128-1 Glioblastoma 19941032 miR-128:Micro-RNA-128 (miRNA-128) down-regulation in glioblastoma targets ARP5 (ANGPTL6), Bmi-1 and E2F-3a, key regulators of brain cell proliferation 2978 hsa-mir-128-2 Glioblastoma 19941032 miR-128:Micro-RNA-128 (miRNA-128) down-regulation in glioblastoma targets ARP5 (ANGPTL6), Bmi-1 and E2F-3a, key regulators of brain cell proliferation 2979 hsa-mir-1302-1 Adenoviridae Infections 20634878 miR-1302-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2980 hsa-mir-1302-2 Adenoviridae Infections 20634878 miR-1302-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2981 hsa-mir-1302-3 Adenoviridae Infections 20634878 miR-1302-3:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2982 hsa-mir-1302-4 Adenoviridae Infections 20634878 miR-1302-4:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2983 hsa-mir-1302-5 Adenoviridae Infections 20634878 miR-1302-5:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2984 hsa-mir-1302-6 Adenoviridae Infections 20634878 miR-1302-6:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2985 hsa-mir-1302-7 Adenoviridae Infections 20634878 miR-1302-7:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2986 hsa-mir-1302-8 Adenoviridae Infections 20634878 miR-1302-8:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 2987 hsa-mir-130a Adrenocortical Adenoma 19849700 miR-130a:miR-130a and miR-382 as putative diagnostic MMAD markers 2988 hsa-mir-130b Prostatic Neoplasms 20875868 miR-130b:The hsa-miR-130b also shows a high variance between samples. 2989 hsa-mir-130b Stomach Neoplasms 20176475 miR-130b:MicroRNA-130b regulates the tumour suppressor RUNX3 in gastric cancer 2990 hsa-mir-132 Neoplasms 20676106 miR-132:miR-132 was highly expressed in the endothelium of human tumors and hemangiomas 2991 hsa-mir-133a-1 Distal Myopathies 20619221 miR-133:have a profound influence on multiple myopathies 2992 hsa-mir-133a-1 Hypertrophy 20619221 miR-133:have a profound influence on multiple myopathies 2993 hsa-mir-133a-1 Myocytes, Cardiac 20173049 miR-133a:NFATc4 is negatively regulated in miR-133a-mediated cardiomyocyte hypertrophic repression 2994 hsa-mir-133a-1 Rhabdomyosarcoma 20466878 miR-133a:mRNA targets of miR-1 and miR-133a are up-regulated in rhabdomyosarcomas 2995 hsa-mir-133a-2 Adenocarcinoma 20413677 miR-133b:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 2996 hsa-mir-133a-2 Distal Myopathies 20619221 miR-133:have a profound influence on multiple myopathies 2997 hsa-mir-133a-2 Hypertrophy 20619221 miR-133:have a profound influence on multiple myopathies 2998 hsa-mir-134 Central Nervous System Diseases 20622856 miR-134:A novel pathway regulates memory and plasticity via SIRT1 and miR-134 2999 hsa-mir-135a-1 Adenocarcinoma 20413677 miR-135a:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 3000 hsa-mir-135a-2 Adenocarcinoma 20413677 miR-135a:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 3001 hsa-mir-137 Astrocytoma 20219352 miR-137:The down-regulation of hsa-miR-137 in astrocytomas was shown to be associated with advanced clinical stages of this disease 3002 hsa-mir-137 Carcinoma, Squamous Cell 20197299 miR-137:MicroRNA-137 promoter methylation in oral rinses from patients with squamous cell carcinoma of the head and neck is associated with gender and body mass index 3003 hsa-mir-137 Melanoma 20644734 miR-137:Our data show that miR-148 and miR-137 present an additional level of regulating Mitf expression in melanocytes and melanoma cells. 3004 hsa-mir-138-1 Carcinoma 20232393 miR-138:miR-138 suppresses TSCC cell migration and invasion by regulating 2 key genes in the Rho GTPase signaling pathway 3005 hsa-mir-138-1 Leukemia 19896708 miR-138:miR-138 might reverse multidrug resistance of leukemia cells 3006 hsa-mir-138-2 Carcinoma 20232393 miR-138:miR-138 suppresses TSCC cell migration and invasion by regulating 2 key genes in the Rho GTPase signaling pathway 3007 hsa-mir-138-2 Leukemia 19896708 miR-138:miR-138 might reverse multidrug resistance of leukemia cells 3008 hsa-mir-140 Osteoarthritis 20516192 miR-140:miR-140 has a critical and nonredundant role in cartilage development and homeostasis 3009 hsa-mir-141 Carcinoma, Hepatocellular 20619223 miR-141:Hsa-miR-141 and hsa-miR-200c, microRNAs that promote epithelial phenotypes, had significantly higher levels in non-hepatic epithelial tumors 3010 hsa-mir-141 Colorectal Neoplasms 19830559 miR-141:miR-141 regulates SIP1 to inhibit migration and invasion of CRC cells 3011 hsa-mir-142 Colonic Neoplasms 20859756 miR-142-3p:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3012 hsa-mir-142 Melanoma 20529253 miR-142-3p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3013 hsa-mir-143 Adenocarcinoma 20301167 miR-143:Expression of miR-143, miR-145 and miR-215 was lower in oesophageal adenocarcinoma than in Barrett's oesophagus 3014 hsa-mir-143 Adenocarcinoma 20413677 miR-143:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 3015 hsa-mir-143 Carcinoma, Non-Small-Cell Lung 20363096 miR-143:Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis 3016 hsa-mir-143 Colorectal Neoplasms 20094072 miR-143:miR-143 and -145 are important onco-related genes for the initiation step of colorectal tumor development 3017 hsa-mir-143 Colorectal Neoplasms 20620599 miR-143:MiR-21 and miR-143 expressions were quantified by using the quantitative reverse transcription polymerase chain reaction method 3018 hsa-mir-143 Neoplasms 20439436 miR-143:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted 3019 hsa-mir-145 Adenocarcinoma 20301167 miR-145:Expression of miR-143, miR-145 and miR-215 was lower in oesophageal adenocarcinoma than in Barrett's oesophagus 3020 hsa-mir-145 Adenocarcinoma 20413677 miR-145:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 3021 hsa-mir-145 Melanoma 20529253 miR-145:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3022 hsa-mir-145 Neoplasms 20439436 miR-145:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted 3023 hsa-mir-145 Prostatic Neoplasms 20588276 miR-145:modulation of miR-145 may be an important therapeutic approach for the management of prostate cancer 3024 hsa-mir-146a Acute Coronary Syndrome 20195282 miR-146a:miR-146a in PBMCs modulates Th1 function in patients with acute coronary syndrome 3025 hsa-mir-146a Arthritis, Psoriatic 20500689 miR-146a:The role of microRNA-146a (miR-146a) and its target IL-1R-associated kinase (IRAK1) in psoriatic arthritis susceptibility 3026 hsa-mir-146a Breast Neoplasms 20099276 miR-146a:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c 3027 hsa-mir-146a Colonic Neoplasms 20859756 miR-146a:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3028 hsa-mir-146a HIV Infections 20181935 mir-146a:CCL8/MCP-2 is a target for mir-146a in HIV-1-infected human microglial cells 3029 hsa-mir-146a Melanoma 20442294 miR-146a:miR-146a and miR-155 were upregulated in all analyzed patients but none of the cell lines 3030 hsa-mir-146a Melanoma 20529253 miR-146a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3031 hsa-mir-146a Neoplasms 20144731 miR-146:in macrophages, miR-125b, miR-146, and miR-155 act as Pathogen Associated Molecular Pattern Molecule-associated microRNAs 3032 hsa-mir-146a Reperfusion Injury 20651252 miR-146a:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI 3033 hsa-mir-146b Adenoviridae Infections 20634878 miR-146b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3034 hsa-mir-146b Carcinoma 20406109 miR-146b:potential importance of miR-221, miR-222, and miR-146b in determining the aggressive properties of PTCs 3035 hsa-mir-148a Adenoviridae Infections 20634878 miR-148a:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3036 hsa-mir-148a Gastrointestinal Neoplasms 20422307 MiR-148a:MiR-148a and miR-152 may be involved in the carcinogenesis of gastrointestinal cancers and might be potential biomarkers 3037 hsa-mir-148a Leukemia, Lymphocytic, Chronic, B-Cell 20504344 miR-148a:miR-148a, miR-222 and miR-21 exhibited a significantly higher expression in non-responder patients 3038 hsa-mir-148a Lung Neoplasms 20431052 miR-148a:The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis 3039 hsa-mir-148a Melanoma 20644734 miR-148:Our data show that miR-148 and miR-137 present an additional level of regulating Mitf expression in melanocytes and melanoma cells. 3040 hsa-mir-148a Prostatic Neoplasms 20406806 miR-148a:MiR-148a attenuates paclitaxel resistance of hormone-refractory, drug-resistant prostate cancer PC3 cells by regulating MSK1 expression 3041 hsa-mir-148b Adenoviridae Infections 20634878 miR-148b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3042 hsa-mir-149 Neoplasms 20623644 miR-149:miR-149* induces apoptosis by inhibiting Akt1 and E2F1 in human cancer cells 3043 hsa-mir-150 Adenoviridae Infections 20634878 miR-150:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3044 hsa-mir-150 Neoplasms 20049626 miR-150:miR-16, miR-17, miR-34a-c, and miR-125 served as tumor suppressor miRNAs, while miR-20, miR-106, and miR-150 acted as oncogenic miRNAs 3045 hsa-mir-150 Neoplasms 20049626 miR-150:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 3046 hsa-mir-151a Melanoma 20529253 miR-151-3p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3047 hsa-mir-151a Neoplasms 20445018 miR-151:down-modulating MPL and other targets of miR-28, and of related miR-708 and miR-151, could contribute to MPN pathogenicity 3048 hsa-mir-152 Carcinoma, Hepatocellular 20578129 microRNA-152:a tumor-suppressive role of miR-152 in the epigenetic aberration of HBV-related HCC 3049 hsa-mir-152 Colonic Neoplasms 20859756 miR-152:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3050 hsa-mir-152 Gastrointestinal Neoplasms 20422307 MiR-152:MiR-148a and miR-152 may be involved in the carcinogenesis of gastrointestinal cancers and might be potential biomarkers 3051 hsa-mir-155 Breast Neoplasms 20371610 miR-155:miR-155 is a critical therapeutic target in breast cancer; MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer 3052 hsa-mir-155 Breast Neoplasms 20664596 miR-155:miR-155, is differentially expressed in ER- versus ER+ tumors 3053 hsa-mir-155 Colitis, Ulcerative 20586854 miR-155:Upregulated miRNA may be responsible for the development of intestinal inflammation in UC 3054 hsa-mir-155 Colonic Neoplasms 20859756 miR-155:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3055 hsa-mir-155 Leukemia, Lymphocytic, Chronic, B-Cell 20393129 miR-155:We found that miR-15a, miR-21, miR-34a, miR-155, and miR-181b were differentially expressed between CLLs with chromosome 17p deletion and CLLs with normal 17p and normal karyotype, and that miR-181b was down-regulated in therapy-refractory cases 3056 hsa-mir-155 Leukemia, Myeloid, Acute 20425795 miR-155:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 3057 hsa-mir-155 Lymphoma, Large-Cell, Anaplastic 20805506 miR-155:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL 3058 hsa-mir-155 Melanoma 20442294 miR-155:miR-146a and miR-155 were upregulated in all analyzed patients but none of the cell lines 3059 hsa-mir-155 Neoplasms 20144731 miR-155:in macrophages, miR-125b, miR-146, and miR-155 act as Pathogen Associated Molecular Pattern Molecule-associated microRNAs 3060 hsa-mir-155 Neoplasms 20144731 miR-155:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a 3061 hsa-mir-155 Pancreatic Neoplasms 20871480 miR-155:Human SMG-1 is Involved in Gemcitabine-Induced Primary microRNA-155/BIC Up-Regulation in Human Pancreatic Cancer PANC-1 Cells 3062 hsa-mir-155 Pre-Eclampsia 20452491 miR-155:MicroRNA-155 contributes to preeclampsia by down-regulating CYR61 3063 hsa-mir-15a Carcinoma, Squamous Cell 20620595 miR-15a:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC 3064 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 20393129 miR-15a:We found that miR-15a, miR-21, miR-34a, miR-155, and miR-181b were differentially expressed between CLLs with chromosome 17p deletion and CLLs with normal 17p and normal karyotype, and that miR-181b was down-regulated in therapy-refractory cases 3065 hsa-mir-15a Multiple Myeloma 20031211 miR-15a:Micro-RNA-15a and micro-RNA-16 expression and chromosome 13 deletions in multiple myeloma 3066 hsa-mir-15b Melanoma 19830692 MiR-15b:MiR-15b and miR-210 were significantly upregulated, miR-34a was significantly downregulated in melanomas 3067 hsa-mir-15b Neoplasms 20154725 miR-15b:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373) 3068 hsa-mir-15b Neoplasms 20404092 mir-15b-16-2:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells 3069 hsa-mir-16-1 Adenocarcinoma 20413677 miR-16:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 3070 hsa-mir-16-1 Multiple Myeloma 20031211 miR-16:Micro-RNA-15a and micro-RNA-16 expression and chromosome 13 deletions in multiple myeloma 3071 hsa-mir-16-1 Neoplasms 20049626 miR-16:miR-16, miR-17, miR-34a-c, and miR-125 served as tumor suppressor miRNAs, while miR-20, miR-106, and miR-150 acted as oncogenic miRNAs 3072 hsa-mir-16-1 Neoplasms 20049626 miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 3073 hsa-mir-16-1 Neoplasms 20154725 miR-16:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373) 3074 hsa-mir-16-1 Neoplasms 20668064 miR-16:miR-16 in the regulation of Wip1 phosphatase in the DNA damage response and mammary tumorigenesis 3075 hsa-mir-16-1 Spinal Cord Injuries 20816819 miR16:SCI results in increased expression of miR Let-7a and miR16 3076 hsa-mir-16-2 Adenocarcinoma 20413677 miR-16:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 3077 hsa-mir-16-2 Multiple Myeloma 20031211 miR-16:Micro-RNA-15a and micro-RNA-16 expression and chromosome 13 deletions in multiple myeloma 3078 hsa-mir-16-2 Neoplasms 20049626 miR-16:miR-16, miR-17, miR-34a-c, and miR-125 served as tumor suppressor miRNAs, while miR-20, miR-106, and miR-150 acted as oncogenic miRNAs 3079 hsa-mir-16-2 Neoplasms 20049626 miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 3080 hsa-mir-16-2 Neoplasms 20154725 miR-16:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373) 3081 hsa-mir-16-2 Neoplasms 20668064 miR-16:miR-16 in the regulation of Wip1 phosphatase in the DNA damage response and mammary tumorigenesis 3082 hsa-mir-16-2 Spinal Cord Injuries 20816819 miR16:SCI results in increased expression of miR Let-7a and miR16 3083 hsa-mir-17 Adenocarcinoma 20413677 miR-17:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 3084 hsa-mir-17 Adenoviridae Infections 20634878 miR-17:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3085 hsa-mir-17 Atherosclerosis 20489169 miR-17-5p:found high levels of expression for all of them in quiescent endothelial cells 3086 hsa-mir-17 Breast Neoplasms 20406904 miR-17:microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer 3087 hsa-mir-17 Leukemia, Myeloid, Acute 20406979 miR-17:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 3088 hsa-mir-17 Lymphoma, B-Cell 19945163 miR-17-5p:the detection of upregulation of miR-17-5p and miR-181a in B- and T-cell lymphomas respectively 3089 hsa-mir-17 Lymphoma, Large-Cell, Anaplastic 20805506 miR-17:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL 3090 hsa-mir-17 Lymphoma, T-Cell 19945163 miR-17-5p:the detection of upregulation of miR-17-5p and miR-181a in B- and T-cell lymphomas respectively 3091 hsa-mir-17 Lymphoma, T-Cell 20448109 mir-17:down-regulation of the miR-17-92 cluster in malignancy 3092 hsa-mir-17 Lymphoma, T-Cell 20448109 miR-17-5p:miR-17-5p expression increases apoptosis and decreases cell proliferation in SzS cells 3093 hsa-mir-106a Colonic Neoplasms 18521848 Deregulated expression of miR-106a predicts survival in human colon cancer patients. 3094 hsa-mir-451a Glioblastoma 18765229 up-regulation in the CD133-cells 3095 hsa-mir-486 Glioblastoma 18765229 up-regulation in the CD133-cells 3096 hsa-mir-425 Glioblastoma 18765229 up-regulation in the CD133-cells 3097 hsa-mir-106a Stomach Neoplasms 18996365 The level of miR-106a in cancer tissues was significantly higher than that in non-tumor tissues, with an average 1.625-fold increase. miR-106a level was significantly associated with tumor stage, size and differentiation; lymphatic and distant metastasis; and invasion (P<0.01). 3098 hsa-mir-133a-1 Heart Defects, Congenital 19015276 microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart 3099 hsa-mir-133a-2 Heart Defects, Congenital 19015276 microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart 3100 hsa-mir-21 Myocytes, Cardiac 19043405 MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts 3101 hsa-mir-133a-1 Heart Failure 19059107 expression decrease 3102 hsa-mir-133a-2 Heart Failure 19059107 expression decrease 3103 hsa-mir-133b Heart Failure 19059107 expression decrease 3104 hsa-mir-1-1 Heart Failure 19059107 expression decrease 3105 hsa-mir-1-2 Heart Failure 19059107 expression decrease 3106 hsa-mir-122 Hypertension 19067360 a polymorphism of the 3'UTR of the SLC7A1 gene affects the binding with miR-122 3107 hsa-mir-133a-1 Heart Failure 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling 3108 hsa-mir-133a-2 Heart Failure 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling 3109 hsa-mir-133b Heart Failure 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling 3110 hsa-mir-30a Heart Failure 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling 3111 hsa-mir-30b Heart Failure 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling 3112 hsa-mir-133a-1 Hypertrophy, Left Ventricular 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling 3113 hsa-mir-133a-2 Hypertrophy, Left Ventricular 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling 3114 hsa-mir-133b Hypertrophy, Left Ventricular 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling 3115 hsa-mir-30a Hypertrophy, Left Ventricular 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling 3116 hsa-mir-30b Hypertrophy, Left Ventricular 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling 3117 hsa-mir-1-1 Arrhythmias, Cardiac 19131648 miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2 3118 hsa-mir-1-2 Arrhythmias, Cardiac 19131648 miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2 3119 hsa-mir-1-1 Cardiomegaly 19188439 MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes 3120 hsa-mir-1-2 Cardiomegaly 19188439 MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes 3121 hsa-mir-21 Myocytes, Cardiac 19336275 MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4 3122 hsa-mir-221 Endothelium, Vascular 19351599 MicroRNA-221 regulates high glucose-induced endothelial dysfunction 3123 hsa-mir-486 Pancreatic Neoplasms 19475450 miR-224 and miR-486 are associated with the progression of pancreatic ductal adenocarcinomas 3124 hsa-mir-224 Pancreatic Neoplasms 19475450 miR-224 and miR-486 are associated with the progression of pancreatic ductal adenocarcinomas 3125 hsa-mir-17 Mesothelioma 19502386 The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype 3126 hsa-mir-21 Mesothelioma 19502386 The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype 3127 hsa-mir-29a Mesothelioma 19502386 The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype 3128 hsa-mir-30e Mesothelioma 19502386 The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype 3129 hsa-mir-106a Mesothelioma 19502386 The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype 3130 hsa-mir-143 Mesothelioma 19502386 The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype 3131 hsa-mir-30c-1 Mesothelioma 19502386 The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype 3132 hsa-mir-30c-2 Mesothelioma 19502386 The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype 3133 hsa-mir-23a Cardiomyopathy, Hypertrophic 19574461 miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy 3134 hsa-mir-221 Prostatic Neoplasms 19585579 miR-221:Expression of microRNA-221 is progressively reduced in aggressive prostate cancer and metastasis 3135 hsa-mir-330 Prostatic Neoplasms 19597470 MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation 3136 hsa-mir-7-2 Parkinson Disease 19628698 expression decreases; miR-7 down-regulates of alpha-expression decreases synuclein, protects cells against oxidative stress 3137 hsa-mir-7-3 Parkinson Disease 19628698 expression decreases; miR-7 down-regulates of alpha-expression decreases synuclein, protects cells against oxidative stress 3138 hsa-mir-188 Myocytes, Cardiac 19669742 These findings suggest that dicer and miRNAs especially miR-188 are involved in Hcy-induced cardiac remodeling 3139 hsa-mir-133a-1 Myocytes, Cardiac 19720047 MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes 3140 hsa-mir-133a-2 Myocytes, Cardiac 19720047 MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes 3141 hsa-mir-133b Myocytes, Cardiac 19720047 MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes 3142 hsa-mir-106b Alopecia 19821055 mir-106b:four microRNAs (miR-221, miR-125b, miR-106b and miR-410) that could participate in pathogenesis of MPB 3143 hsa-mir-125b-1 Alopecia 19821055 miR-125b:four microRNAs (miR-221, miR-125b, miR-106b and miR-410) that could participate in pathogenesis of MPB 3144 hsa-mir-125b-2 Alopecia 19821055 miR-125b:four microRNAs (miR-221, miR-125b, miR-106b and miR-410) that could participate in pathogenesis of MPB 3145 hsa-mir-221 Alopecia 19821055 miR-221:four microRNAs (miR-221, miR-125b, miR-106b and miR-410) that could participate in pathogenesis of MPB 3146 hsa-mir-410 Alopecia 19821055 miR-410:four microRNAs (miR-221, miR-125b, miR-106b and miR-410) that could participate in pathogenesis of MPB 3147 hsa-mir-150 Sepsis 19823581 miR-150 as a plasma prognostic marker in patients with sepsis 3148 hsa-mir-182 Sepsis 19823581 we found that miR-150, miR-182, miR-342-5p, and miR-486 expression profiles differentiated sepsis patients from healthy controls 3149 hsa-mir-342 Sepsis 19823581 we found that miR-150, miR-182, miR-342-5p, and miR-486 expression profiles differentiated sepsis patients from healthy controls 3150 hsa-mir-486 Sepsis 19823581 we found that miR-150, miR-182, miR-342-5p, and miR-486 expression profiles differentiated sepsis patients from healthy controls 3151 hsa-mir-210 Melanoma 19830692 miR-210:MiR-15b and miR-210 were significantly upregulated, miR-34a was significantly downregulated in melanomas 3152 hsa-mir-34a Melanoma 19830692 miR-34a:MiR-15b and miR-210 were significantly upregulated, miR-34a was significantly downregulated in melanomas 3153 hsa-mir-196a-2 Stomach Neoplasms 19834808 miR-196a-2:Association of microRNA-196a-2 gene polymorphism with gastric cancer risk 3154 hsa-mir-200a Breast Neoplasms 19839049 miR-200a:microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells 3155 hsa-mir-200b Breast Neoplasms 19839049 miR-200b:microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells 3156 hsa-mir-200c Breast Neoplasms 19839049 miR-200c:microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells 3157 hsa-mir-203 Carcinoma, Hepatocellular 19843643 miR-203:miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. 3158 hsa-mir-200b Adrenocortical Adenoma 19849700 miR-200b:miR-200b may play a significant role in MMAD formation and/or progression; 16 microRNAs were down-regulated, including miR-200b and miR-203, whereas 21 microRNAs were up-regulated, miR-210 and miR-484 among them 3159 hsa-mir-203 Adrenocortical Adenoma 19849700 miR-203:16 microRNAs were down-regulated, including miR-200b and miR-203, whereas 21 microRNAs were up-regulated, miR-210 and miR-484 among them 3160 hsa-mir-210 Adrenocortical Adenoma 19849700 miR-210:16 microRNAs were down-regulated, including miR-200b and miR-203, whereas 21 microRNAs were up-regulated, miR-210 and miR-484 among them 3161 hsa-mir-382 Adrenocortical Adenoma 19849700 miR-382:miR-130a and miR-382 as putative diagnostic MMAD markers 3162 hsa-mir-484 Adrenocortical Adenoma 19849700 miR-484:16 microRNAs were down-regulated, including miR-200b and miR-203, whereas 21 microRNAs were up-regulated, miR-210 and miR-484 among them 3163 hsa-mir-29a Colorectal Neoplasms 19876917 miR-29a:plasma miR-29a and miR-92a have significant diagnostic value for advanced neoplasia 3164 hsa-mir-92a-1 Colorectal Neoplasms 19876917 miR-92a:plasma miR-29a and miR-92a have significant diagnostic value for advanced neoplasia 3165 hsa-mir-92a-2 Colorectal Neoplasms 19876917 miR-92a:plasma miR-29a and miR-92a have significant diagnostic value for advanced neoplasia 3166 hsa-mir-326 Breast Neoplasms 19883630 Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1 3167 hsa-mir-145 Myelodysplastic Syndromes 19898489 5q- syndrome deleted,Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype 3168 hsa-mir-146a Myelodysplastic Syndromes 19898489 5q- syndrome deleted,Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype 3169 hsa-mir-199b Choriocarcinoma 19900756 miR-199b:Decreased expression of microRNA-199b increases protein levels of SET (protein phosphatase 2A inhibitor) in human choriocarcinoma 3170 hsa-mir-25 Myocardium 19919989 miR-25 and miR-29a were sufficient to decrease collagen gene expression when transfected into isolated cardiac fibroblasts in vitro 3171 hsa-mir-29a Myocardium 19919989 miR-25 and miR-29a were sufficient to decrease collagen gene expression when transfected into isolated cardiac fibroblasts in vitro 3172 hsa-mir-34a Lung Neoplasms 19921694 miR-34a:MicroRNA-34a is an important component of PRIMA-1-induced apoptotic network in human lung cancer cells 3173 hsa-mir-181a-1 Lymphoma, B-Cell 19945163 miR-181a:the detection of upregulation of miR-17-5p and miR-181a in B- and T-cell lymphomas respectively 3174 hsa-mir-181a-1 Lymphoma, T-Cell 19945163 miR-181a:the detection of upregulation of miR-17-5p and miR-181a in B- and T-cell lymphomas respectively 3175 hsa-mir-181a-2 Lymphoma, B-Cell 19945163 miR-181a:the detection of upregulation of miR-17-5p and miR-181a in B- and T-cell lymphomas respectively 3176 hsa-mir-181a-2 Lymphoma, T-Cell 19945163 miR-181a:the detection of upregulation of miR-17-5p and miR-181a in B- and T-cell lymphomas respectively 3177 hsa-mir-133b Breast Neoplasms 19946373 downregulated 3178 hsa-mir-133b Colonic Neoplasms 19946373 downregulated 3179 hsa-mir-133b Liver Neoplasms 19946373 downregulated 3180 hsa-mir-133b Lung Neoplasms 19946373 downregulated 3181 hsa-mir-133b Lymphoma 19946373 downregulated 3182 hsa-mir-133b Ovarian Neoplasms 19946373 downregulated 3183 hsa-mir-133b Prostatic Neoplasms 19946373 downregulated 3184 hsa-mir-133b Testicular Neoplasms 19946373 downregulated 3185 hsa-mir-486 Breast Neoplasms 19946373 miR-486-5p: downregulated 3186 hsa-mir-486 Colonic Neoplasms 19946373 miR-486-5p: downregulated 3187 hsa-mir-486 Liver Neoplasms 19946373 miR-486-5p: downregulated 3188 hsa-mir-486 Lung Neoplasms 19946373 miR-486-5p: downregulated 3189 hsa-mir-486 Lymphoma 19946373 miR-486-5p: downregulated 3190 hsa-mir-486 Ovarian Neoplasms 19946373 miR-486-5p: downregulated 3191 hsa-mir-486 Prostatic Neoplasms 19946373 miR-486-5p: downregulated 3192 hsa-mir-486 Testicular Neoplasms 19946373 miR-486-5p: downregulated 3193 hsa-mir-629 Breast Neoplasms 19946373 upregulated 3194 hsa-mir-629 Colonic Neoplasms 19946373 upregulated 3195 hsa-mir-629 Liver Neoplasms 19946373 upregulated 3196 hsa-mir-629 Lung Neoplasms 19946373 upregulated 3197 hsa-mir-629 Lymphoma 19946373 upregulated 3198 hsa-mir-629 Ovarian Neoplasms 19946373 upregulated 3199 hsa-mir-629 Prostatic Neoplasms 19946373 upregulated 3200 hsa-mir-629 Testicular Neoplasms 19946373 upregulated 3201 hsa-mir-29a Irritable Bowel Syndrome 19951903 miR-29a:MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome 3202 hsa-mir-326 Brain Neoplasms 19955368 The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors 3203 hsa-mir-27a Carcinoma, Squamous Cell 19960259 miR-27a:Down-regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma 3204 hsa-mir-133a-1 Cardiomyopathy, Hypertrophic 20013939 miR133a regulates cardiomyocyte hypertrophy in diabetes 3205 hsa-mir-133a-2 Cardiomyopathy, Hypertrophic 20013939 miR133a regulates cardiomyocyte hypertrophy in diabetes 3206 hsa-mir-223 Leukemia, Myeloid, Acute 20018373 miR-223:miR-223 suppression in AML is caused by impaired miR-223 upstream factors 3207 hsa-mir-212 Stomach Neoplasms 20020497 miR-212:miR-212 is downregulated and suppresses methyl-CpG-binding protein MeCP2 in human gastric cancer 3208 hsa-mir-9-1 Endometrial Neoplasms 20028871 Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1 3209 hsa-mir-9-2 Endometrial Neoplasms 20028871 Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1 3210 hsa-mir-9-3 Endometrial Neoplasms 20028871 Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1 3211 hsa-mir-27a Endometrial Neoplasms 20028871 Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1 3212 hsa-mir-27b Endometrial Neoplasms 20028871 Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1 3213 hsa-mir-96 Endometrial Neoplasms 20028871 Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1 3214 hsa-mir-153-1 Endometrial Neoplasms 20028871 Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1 3215 hsa-mir-153-2 Endometrial Neoplasms 20028871 Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1 3216 hsa-mir-182 Endometrial Neoplasms 20028871 Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1 3217 hsa-mir-183 Endometrial Neoplasms 20028871 Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1 3218 hsa-mir-186 Endometrial Neoplasms 20028871 Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1 3219 hsa-mir-200a Ovarian Neoplasms 20035894 miR-200a:involved in epithelial-to-mesenchymal transition (EMT) 3220 hsa-mir-200b Ovarian Neoplasms 20035894 miR-200b:involved in epithelial-to-mesenchymal transition (EMT) 3221 hsa-mir-200c Ovarian Neoplasms 20035894 miR-200c:involved in epithelial-to-mesenchymal transition (EMT) 3222 hsa-mir-491 Colorectal Neoplasms 20039318 miR-491:Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-X(L) in colorectal cancer cells 3223 hsa-mir-492 Colorectal Neoplasms 20044760 mir-492:In a univariate analysis, the progression-free survival of the patients with the combined mir492 C/G and G/G genotype was significantly worse than that of the patients with the mir492 C/C genotype (rs2289030) (P value = 0.0426) 3224 hsa-mir-17 Neoplasms 20049626 miR-17:miR-16, miR-17, miR-34a-c, and miR-125 served as tumor suppressor miRNAs, while miR-20, miR-106, and miR-150 acted as oncogenic miRNAs 3225 hsa-mir-17 Neoplasms 20049626 miR-17-5p:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 3226 hsa-mir-20a Neoplasms 20049626 miR-20:miR-16, miR-17, miR-34a-c, and miR-125 served as tumor suppressor miRNAs, while miR-20, miR-106, and miR-150 acted as oncogenic miRNAs 3227 hsa-mir-34a Neoplasms 20049626 miR-34a:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 3228 hsa-mir-34a Neoplasms 20049626 miR-34a-c:miR-16, miR-17, miR-34a-c, and miR-125 served as tumor suppressor miRNAs, while miR-20, miR-106, and miR-150 acted as oncogenic miRNAs 3229 hsa-mir-34b Neoplasms 20049626 miR-34b:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 3230 hsa-mir-34c Neoplasms 20049626 miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 3231 hsa-mir-205 Trophoblasts 20065103 miR-205:MiR-205 silences MED1 in hypoxic primary human trophoblasts; a set of seven miRNAs (miR-93, miR-205, miR-224, miR-335, miR-424, miR-451, and miR-491) that are differentially regulated in primary trophoblasts 3232 hsa-mir-224 Trophoblasts 20065103 miR-224:a set of seven miRNAs (miR-93, miR-205, miR-224, miR-335, miR-424, miR-451, and miR-491) that are differentially regulated in primary trophoblasts 3233 hsa-mir-335 Trophoblasts 20065103 miR-335:a set of seven miRNAs (miR-93, miR-205, miR-224, miR-335, miR-424, miR-451, and miR-491) that are differentially regulated in primary trophoblasts 3234 hsa-mir-424 Trophoblasts 20065103 miR-424:a set of seven miRNAs (miR-93, miR-205, miR-224, miR-335, miR-424, miR-451, and miR-491) that are differentially regulated in primary trophoblasts 3235 hsa-mir-451a Trophoblasts 20065103 miR-451:a set of seven miRNAs (miR-93, miR-205, miR-224, miR-335, miR-424, miR-451, and miR-491) that are differentially regulated in primary trophoblasts 3236 hsa-mir-491 Trophoblasts 20065103 miR-491:a set of seven miRNAs (miR-93, miR-205, miR-224, miR-335, miR-424, miR-451, and miR-491) that are differentially regulated in primary trophoblasts 3237 hsa-mir-93 Trophoblasts 20065103 miR-93:a set of seven miRNAs (miR-93, miR-205, miR-224, miR-335, miR-424, miR-451, and miR-491) that are differentially regulated in primary trophoblasts 3238 hsa-mir-193b Prostatic Neoplasms 20073067 miR-193b:miR-193b is an epigenetically regulated putative tumor suppressor in prostate cancer 3239 hsa-mir-181c Stomach Neoplasms 20080834 miR-181c:Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis. 3240 hsa-mir-34a Leukemia, Lymphocytic, Chronic, B-Cell 20089965 miR-34a:microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia 3241 hsa-mir-200b Breast Neoplasms 20099276 miR-200b:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c 3242 hsa-mir-200c Breast Neoplasms 20099276 miR-200c:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c 3243 hsa-mir-221 Breast Neoplasms 20099276 miR-221:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c 3244 hsa-mir-222 Breast Neoplasms 20099276 miR-222:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c 3245 hsa-mir-345 Breast Neoplasms 20099276 miR-345:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c 3246 hsa-mir-345 Breast Neoplasms 20099276 miR-345:miR-345 and miR-7 target the human multidrug resistance-associated protein 1 3247 hsa-mir-7-1 Breast Neoplasms 20099276 miR-7:miR-345 and miR-7 target the human multidrug resistance-associated protein 1 3248 hsa-mir-7-2 Breast Neoplasms 20099276 miR-7:miR-345 and miR-7 target the human multidrug resistance-associated protein 1 3249 hsa-mir-7-3 Breast Neoplasms 20099276 miR-7:miR-345 and miR-7 target the human multidrug resistance-associated protein 1 3250 hsa-mir-196a-1 Carcinoma, Hepatocellular 20127796 miR-196:MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression 3251 hsa-mir-196a-2 Carcinoma, Hepatocellular 20127796 miR-196:MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression 3252 hsa-mir-27b Osteoarthritis 20131257 miR-27b:MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes 3253 hsa-mir-17 Neoplasms 20144731 miR-17:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a 3254 hsa-mir-181a-1 Neoplasms 20144731 miR-181a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a 3255 hsa-mir-181a-2 Neoplasms 20144731 miR-181a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a 3256 hsa-mir-18a Neoplasms 20144731 miR-18a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a 3257 hsa-mir-19a Neoplasms 20144731 miR-19a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a 3258 hsa-mir-19b-1 Neoplasms 20144731 miR-19b:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a 3259 hsa-mir-19b-2 Neoplasms 20144731 miR-19b:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a 3260 hsa-mir-20a Neoplasms 20144731 miR-20a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a 3261 hsa-mir-214 Neoplasms 20144731 miR-214:miR-34C and miR-214 as Damage Associated Molecular Pattern Molecules-associated miRs 3262 hsa-mir-34c Neoplasms 20144731 miR-34c:miR-34C and miR-214 as Damage Associated Molecular Pattern Molecules-associated miRs 3263 hsa-mir-92a-1 Neoplasms 20144731 miR-92a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a 3264 hsa-mir-92a-2 Neoplasms 20144731 miR-92a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a 3265 hsa-mir-21 Neoplasms 20154725 miR-21:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373) 3266 hsa-mir-372 Neoplasms 20154725 miR-372:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373) 3267 hsa-mir-373 Neoplasms 20154725 miR-373:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373) 3268 hsa-mir-181b-1 Lung Neoplasms 20162574 miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines 3269 hsa-mir-181b-2 Lung Neoplasms 20162574 miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines 3270 hsa-mir-181b-1 Stomach Neoplasms 20162574 miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines 3271 hsa-mir-181b-2 Stomach Neoplasms 20162574 miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines 3272 hsa-mir-181b-1 Adenocarcinoma 20162574 miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines 3273 hsa-mir-181b-2 Adenocarcinoma 20162574 miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines 3274 hsa-mir-218-1 Uterine Cervical Neoplasms 20163849 miR-218:Polymorphisms involved in the miR-218-LAMB3 pathway and susceptibility of cervical cancer 3275 hsa-mir-218-2 Uterine Cervical Neoplasms 20163849 miR-218:Polymorphisms involved in the miR-218-LAMB3 pathway and susceptibility of cervical cancer 3276 hsa-mir-9-1 Cardiomyopathy, Hypertrophic 20177053 miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy 3277 hsa-mir-9-2 Cardiomyopathy, Hypertrophic 20177053 miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy 3278 hsa-mir-9-3 Cardiomyopathy, Hypertrophic 20177053 miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy 3279 hsa-mir-433 Chondrodysplasia Punctata 20181727 miR-433:A mutation in the 3'-UTR of the HDAC6 gene abolishing the post-transcriptional regulation mediated by hsa-miR-433 is linked to a new form of dominant X-linked chondrodysplasia 3280 hsa-mir-423 Heart Failure 20185794 MiR423-5p as a circulating biomarker for heart failure 3281 hsa-mir-210 Carcinoma, Squamous Cell 20187102 mir-210:hsa-mir-210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer 3282 hsa-mir-196a-2 Carcinoma, Hepatocellular 20188135 miR-196a2:MIR196A2 polymorphism was associated with susceptibility to HBV-related HCC in a maleChinese population. 3283 hsa-mir-199a-1 Anoxia 20193759 miR-199a-5p:activation of beta-adrenergic signaling counteracts the survival effects of the AKT pathway via upregulating miR-199a-5p 3284 hsa-mir-199a-2 Anoxia 20193759 miR-199a-5p:activation of beta-adrenergic signaling counteracts the survival effects of the AKT pathway via upregulating miR-199a-5p 3285 hsa-mir-486 Carcinoma, Non-Small-Cell Lung 20194856 significantly associated with overal survival 3286 hsa-mir-30d Carcinoma, Non-Small-Cell Lung 20194856 significantly associated with overal survival 3287 hsa-mir-1-1 Carcinoma, Non-Small-Cell Lung 20194856 significantly associated with overal survival 3288 hsa-mir-1-2 Carcinoma, Non-Small-Cell Lung 20194856 significantly associated with overal survival 3289 hsa-mir-499a Carcinoma, Non-Small-Cell Lung 20194856 significantly associated with overal survival 3290 hsa-mir-221 Leukemia, Lymphocytic, Chronic, B-Cell 20203269 miR-221:miR-221/222 and p27 may represent a regulatory loop that helps maintaining CLL cells in a resting condition 3291 hsa-mir-222 Leukemia, Lymphocytic, Chronic, B-Cell 20203269 miR-222:miR-221/222 and p27 may represent a regulatory loop that helps maintaining CLL cells in a resting condition 3292 hsa-mir-181b-1 Astrocytoma 20219352 miR-181b:hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma 3293 hsa-mir-181b-2 Astrocytoma 20219352 miR-181b:hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma 3294 hsa-mir-21 Astrocytoma 20219352 miR-21:hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma 3295 hsa-mir-182 Leukemia, Biphenotypic, Acute 20227111 miR-182:miR-584 and miR-182 upregulation in the CD34(+)CD38(-) fraction 3296 hsa-mir-584 Leukemia, Biphenotypic, Acute 20227111 miR-584:miR-584 and miR-182 upregulation in the CD34(+)CD38(-) fraction 3297 hsa-mir-17 Neoplasms 20227518 miR-17:mir-17-92, a cluster of miRNAs in the midst of the cancer network 3298 hsa-mir-18a Neoplasms 20227518 miR-18a:mir-17-92, a cluster of miRNAs in the midst of the cancer network 3299 hsa-mir-19a Neoplasms 20227518 miR-19a:mir-17-92, a cluster of miRNAs in the midst of the cancer network 3300 hsa-mir-19b-1 Neoplasms 20227518 miR-19b:mir-17-92, a cluster of miRNAs in the midst of the cancer network 3301 hsa-mir-19b-2 Neoplasms 20227518 miR-19b:mir-17-92, a cluster of miRNAs in the midst of the cancer network 3302 hsa-mir-20a Neoplasms 20227518 miR-20a:mir-17-92, a cluster of miRNAs in the midst of the cancer network 3303 hsa-mir-92a-1 Neoplasms 20227518 miR-92a:mir-17-92, a cluster of miRNAs in the midst of the cancer network 3304 hsa-mir-92a-2 Neoplasms 20227518 miR-92a:mir-17-92, a cluster of miRNAs in the midst of the cancer network 3305 hsa-mir-20b Breast Neoplasms 20232316 miR-20b:miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells 3306 hsa-mir-31 Mouth Neoplasms 20233326 miR-31:Increase of microRNA miR-31 level in plasma could be a potential marker of oral cancer 3307 hsa-mir-203 Adenocarcinoma 20301167 miR-203:Levels of miR-203 and miR-205 were high in normal squamous epithelium and low in columnar epithelia 3308 hsa-mir-205 Adenocarcinoma 20301167 miR-205:Levels of miR-203 and miR-205 were high in normal squamous epithelium and low in columnar epithelia 3309 hsa-mir-215 Adenocarcinoma 20301167 miR-215:Expression of miR-143, miR-145 and miR-215 was lower in oesophageal adenocarcinoma than in Barrett's oesophagus 3310 hsa-mir-30e Schizophrenia 20347265 miR-30e:mir-30e ss178077483 plays a role in schizophrenia susceptibility 3311 hsa-mir-17 Stomach Neoplasms 20349219 miR-17:detection of miRNA in peripheral blood may be a novel tool for monitoring circulating tumor cells in patients with gastric cancers 3312 hsa-mir-106a Stomach Neoplasms 20349219 miR-106a and miR-17 levels were significantly higher than those in controls 3313 hsa-mir-17 Stomach Neoplasms 20349219 miR-106a and miR-17 levels were significantly higher than those in controls 3314 hsa-mir-34a Carcinoma 20351093 miR-34a:MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells 3315 hsa-mir-34a Choriocarcinoma 20351093 miR-34a:MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells 3316 hsa-mir-191 Melanoma 20357817 miR-191:low expression of miR-191 and high expression of miR-193b were associated with poor melanoma-specific survival 3317 hsa-mir-193a Melanoma 20357817 miR-193a:In melanomas, miR-193a, miR-338, and miR-565 were underexpressed in cases with a BRAF mutation 3318 hsa-mir-193b Melanoma 20357817 miR-193b:low expression of miR-191 and high expression of miR-193b were associated with poor melanoma-specific survival 3319 hsa-mir-338 Melanoma 20357817 miR-338:In melanomas, miR-193a, miR-338, and miR-565 were underexpressed in cases with a BRAF mutation 3320 hsa-mir-181a-1 Carcinoma, Non-Small-Cell Lung 20363096 miR-181a:Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis 3321 hsa-mir-181a-2 Carcinoma, Non-Small-Cell Lung 20363096 miR-181a:Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis 3322 hsa-mir-21 Carcinoma, Non-Small-Cell Lung 20363096 miR-21:Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis 3323 hsa-mir-512-1 Carcinoma, Hepatocellular 20372864 miR-512-3p:Inhibition of c-FLIP expression by miR-512-3p contributes to taxol-induced apoptosis in hepatocellular carcinoma cells 3324 hsa-mir-512-2 Carcinoma, Hepatocellular 20372864 miR-512-3p:Inhibition of c-FLIP expression by miR-512-3p contributes to taxol-induced apoptosis in hepatocellular carcinoma cells 3325 hsa-mir-142 Glioblastoma 20380575 miR-142-3p:The miR-17-3p, miR-17-5p, miR-19a, miR-19b, miR-142-3p, and miR-142-5p were upregulated in both M059K and M059J cells. 3326 hsa-mir-142 Glioblastoma 20380575 miR-142-5p:The miR-17-3p, miR-17-5p, miR-19a, miR-19b, miR-142-3p, and miR-142-5p were upregulated in both M059K and M059J cells. 3327 hsa-mir-143 Glioblastoma 20380575 miR-143:The miR-15a, miR-16, miR-143, miR-155, and miR-21 were upregulated in M059K 3328 hsa-mir-155 Glioblastoma 20380575 miR-155:The miR-15a, miR-16, miR-143, miR-155, and miR-21 were upregulated in M059K 3329 hsa-mir-15a Glioblastoma 20380575 miR-15a:The miR-15a, miR-16, miR-143, miR-155, and miR-21 were upregulated in M059K 3330 hsa-mir-16-1 Glioblastoma 20380575 miR-16:The miR-15a, miR-16, miR-143, miR-155, and miR-21 were upregulated in M059K 3331 hsa-mir-16-2 Glioblastoma 20380575 miR-16:The miR-15a, miR-16, miR-143, miR-155, and miR-21 were upregulated in M059K 3332 hsa-mir-17 Glioblastoma 20380575 miR-17-3p:The miR-17-3p, miR-17-5p, miR-19a, miR-19b, miR-142-3p, and miR-142-5p were upregulated in both M059K and M059J cells. 3333 hsa-mir-17 Glioblastoma 20380575 miR-17-5p:The miR-17-3p, miR-17-5p, miR-19a, miR-19b, miR-142-3p, and miR-142-5p were upregulated in both M059K and M059J cells. 3334 hsa-mir-19a Glioblastoma 20380575 miR-19a:The miR-17-3p, miR-17-5p, miR-19a, miR-19b, miR-142-3p, and miR-142-5p were upregulated in both M059K and M059J cells. 3335 hsa-mir-19b-1 Glioblastoma 20380575 miR-19b:The miR-17-3p, miR-17-5p, miR-19a, miR-19b, miR-142-3p, and miR-142-5p were upregulated in both M059K and M059J cells. 3336 hsa-mir-19b-2 Glioblastoma 20380575 miR-19b:The miR-17-3p, miR-17-5p, miR-19a, miR-19b, miR-142-3p, and miR-142-5p were upregulated in both M059K and M059J cells. 3337 hsa-mir-21 Glioblastoma 20380575 miR-21:The miR-15a, miR-16, miR-143, miR-155, and miR-21 were upregulated in M059K 3338 hsa-mir-27a Breast Neoplasms 20382698 miR-27a:MicroRNA-27a Indirectly Regulates Estrogen Receptor {alpha} Expression and Hormone Responsiveness in MCF-7 Breast Cancer Cells 3339 hsa-mir-200a Pancreatic Neoplasms 20388782 miR-200:Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF 3340 hsa-mir-21 Pancreatic Neoplasms 20388782 miR-21:Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF 3341 hsa-mir-212 Carcinoma, Non-Small-Cell Lung 20388802 miR-212:miR-212 increases tumor necrosis factor-related apoptosis-inducing ligand sensitivity in non-small cell lung cancer by targeting the antiapoptotic protein PED 3342 hsa-mir-221 Breast Neoplasms 20388878 miR-221:MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer 3343 hsa-mir-222 Breast Neoplasms 20388878 miR-222:MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer 3344 hsa-mir-181b-1 Leukemia, Lymphocytic, Chronic, B-Cell 20393129 miR-181b:We found that miR-15a, miR-21, miR-34a, miR-155, and miR-181b were differentially expressed between CLLs with chromosome 17p deletion and CLLs with normal 17p and normal karyotype, and that miR-181b was down-regulated in therapy-refractory cases 3345 hsa-mir-181b-2 Leukemia, Lymphocytic, Chronic, B-Cell 20393129 miR-181b:We found that miR-15a, miR-21, miR-34a, miR-155, and miR-181b were differentially expressed between CLLs with chromosome 17p deletion and CLLs with normal 17p and normal karyotype, and that miR-181b was down-regulated in therapy-refractory cases 3346 hsa-mir-21 Leukemia, Lymphocytic, Chronic, B-Cell 20393129 miR-21:microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival 3347 hsa-mir-34a Leukemia, Lymphocytic, Chronic, B-Cell 20393129 miR-34a:We found that miR-15a, miR-21, miR-34a, miR-155, and miR-181b were differentially expressed between CLLs with chromosome 17p deletion and CLLs with normal 17p and normal karyotype, and that miR-181b was down-regulated in therapy-refractory cases 3348 hsa-mir-208a Myocardium 20395621 miR-208:plasma miR-208 is a biomarker of myocardial injury 3349 hsa-mir-499a Myocardial Infarction 20395621 Plasma microRNA 499 as a biomarker of acute myocardial infarction 3350 hsa-mir-199a-1 Ovarian Neoplasms 20400975 miR-199a:TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214 3351 hsa-mir-199a-2 Ovarian Neoplasms 20400975 miR-199a:TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214 3352 hsa-mir-214 Ovarian Neoplasms 20400975 miR-214:TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214 3353 hsa-mir-25 Neoplasms 20404092 mir-106b-25:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells 3354 hsa-mir-93 Neoplasms 20404092 mir-106b-25:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells 3355 hsa-mir-21 Neoplasms 20404348 miR-21:function of AKT by which it inhibits apoptosis through miR-21-dependent suppression of FasL 3356 hsa-mir-21 Myocytes, Cardiac 20404348 MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligand 3357 hsa-mir-221 Carcinoma 20406109 miR-221:potential importance of miR-221, miR-222, and miR-146b in determining the aggressive properties of PTCs 3358 hsa-mir-222 Carcinoma 20406109 miR-222:potential importance of miR-221, miR-222, and miR-146b in determining the aggressive properties of PTCs 3359 hsa-mir-20a Breast Neoplasms 20406904 miR-20:microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer 3360 hsa-mir-18a Leukemia, Myeloid, Acute 20406979 miR-18a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 3361 hsa-mir-19a Leukemia, Myeloid, Acute 20406979 miR-19a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 3362 hsa-mir-19b-1 Leukemia, Myeloid, Acute 20406979 miR-19b:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 3363 hsa-mir-19b-2 Leukemia, Myeloid, Acute 20406979 miR-19b:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 3364 hsa-mir-20a Leukemia, Myeloid, Acute 20406979 miR-20a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 3365 hsa-mir-92a-1 Leukemia, Myeloid, Acute 20406979 miR-92a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 3366 hsa-mir-92a-2 Leukemia, Myeloid, Acute 20406979 miR-92a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 3367 hsa-mir-183 Adenocarcinoma 20413677 miR-183:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 3368 hsa-mir-191 Adenocarcinoma 20413677 miR-191:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 3369 hsa-mir-192 Adenocarcinoma 20413677 miR-192:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 3370 hsa-mir-196a-1 Adenocarcinoma 20413677 miR-196a:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 3371 hsa-mir-196a-2 Adenocarcinoma 20413677 miR-196a:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 3372 hsa-mir-203 Adenocarcinoma 20413677 miR-203:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 3373 hsa-mir-20a Adenocarcinoma 20413677 miR-20:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 3374 hsa-mir-215 Adenocarcinoma 20413677 miR-215:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 3375 hsa-mir-223 Adenocarcinoma 20413677 miR-223:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 3376 hsa-mir-25 Adenocarcinoma 20413677 miR-25:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 3377 hsa-mir-26b Adenocarcinoma 20413677 miR-26b:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC 3378 hsa-mir-31 Adenocarcinoma 20413677 miR-31:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 3379 hsa-mir-92a-1 Adenocarcinoma 20413677 miR-92:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 3380 hsa-mir-92a-2 Adenocarcinoma 20413677 miR-92:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 3381 hsa-mir-93 Adenocarcinoma 20413677 miR-93:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa, 3382 hsa-mir-223 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 20418243 miR-223:over-expression of miR-223 3383 hsa-mir-182 Lung Neoplasms 20420807 mir-182:Hsa-mir-182 suppresses lung tumorigenesis through down regulation of RGS17 expression in vitro 3384 hsa-mir-372 Liver Neoplasms 20423907 microRNA-372:CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer 3385 hsa-mir-17 Toxoplasmosis 20423977 hsa-mir-17:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii 3386 hsa-mir-18a Toxoplasmosis 20423977 hsa-mir-18a:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii 3387 hsa-mir-18b Toxoplasmosis 20423977 hsa-mir-18b:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii 3388 hsa-mir-20a Toxoplasmosis 20423977 hsa-mir-20a:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii 3389 hsa-mir-20b Toxoplasmosis 20423977 hsa-mir-20b:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii 3390 hsa-mir-93 Toxoplasmosis 20423977 hsa-mir-93:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii 3391 hsa-mir-451a Erythropoiesis 20424607 miR-451:a loss of miR-451, a small RNA important for erythropoiesis 3392 hsa-mir-196b Leukemia, Myeloid, Acute 20425795 miR-196b:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 3393 hsa-mir-221 Leukemia, Myeloid, Acute 20425795 miR-221:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 3394 hsa-mir-98 Leukemia, Myeloid, Acute 20425795 hsa-mir-98:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes. 3395 hsa-mir-221 Glioblastoma 20428775 miR-221:STAT1/2 upregulation under the transcriptional control of INF-alpha signaling after knockdown of miR-221/222 cluster in U251 glioma cells 3396 hsa-mir-222 Glioblastoma 20428775 miR-222:STAT1/2 upregulation under the transcriptional control of INF-alpha signaling after knockdown of miR-221/222 cluster in U251 glioma cells 3397 hsa-mir-205 Carcinoma, Squamous Cell 20428818 miR-205:miR-205 and miR-21 are specific markers for HNSCC and ESCC 3398 hsa-mir-205 Esophagus 20428818 miR-205:miR-205 and miR-21 are specific markers for HNSCC and ESCC 3399 hsa-mir-21 Carcinoma, Squamous Cell 20428818 miR-21:miR-205 and miR-21 are specific markers for HNSCC and ESCC 3400 hsa-mir-21 Esophagus 20428818 miR-21:miR-205 and miR-21 are specific markers for HNSCC and ESCC 3401 hsa-mir-17 Neoplasms 20439436 mir-17:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted 3402 hsa-mir-18a Neoplasms 20439436 mir-18a:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted 3403 hsa-mir-19a Neoplasms 20439436 mir-19a:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted 3404 hsa-mir-19b-1 Neoplasms 20439436 mir-19b:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted 3405 hsa-mir-19b-2 Neoplasms 20439436 mir-19b:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted 3406 hsa-mir-204 Neoplasms 20439436 miR-204:hsa-miR-30 and hsa-miR-204, were found to be physically altered at the DNA copy number level as well 3407 hsa-mir-20a Neoplasms 20439436 mir-20a:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted 3408 hsa-mir-30a Neoplasms 20439436 miR-30:hsa-miR-103/106 were downgraded in cancer, whereas hsa-miR-30 became most prominent 3409 hsa-mir-30a Neoplasms 20439436 miR-30:hsa-miR-30 and hsa-miR-204, were found to be physically altered at the DNA copy number level as well 3410 hsa-mir-92a-1 Neoplasms 20439436 mir-92a:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted 3411 hsa-mir-92a-2 Neoplasms 20439436 mir-92a:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted 3412 hsa-mir-200c Melanoma 20442294 miRNA-200c:miRNA-200c to be consistently downregulated in melanocytes, melanoma cell lines, and patient samples, whereas miRNA-205 and miRNA-23b were markedly reduced only in patient samples 3413 hsa-mir-205 Melanoma 20442294 miRNA-205:miRNA-200c to be consistently downregulated in melanocytes, melanoma cell lines, and patient samples, whereas miRNA-205 and miRNA-23b were markedly reduced only in patient samples 3414 hsa-mir-23b Melanoma 20442294 miRNA-23b:miRNA-200c to be consistently downregulated in melanocytes, melanoma cell lines, and patient samples, whereas miRNA-205 and miRNA-23b were markedly reduced only in patient samples 3415 hsa-mir-195 Glioblastoma 20444541 miR-195:miR-195, miR-455-3p and miR-10a( *) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells 3416 hsa-mir-455 Glioblastoma 20444541 miR-455-3p:miR-195, miR-455-3p and miR-10a( *) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells 3417 hsa-mir-28 Neoplasms 20445018 miR-28:down-modulating MPL and other targets of miR-28, and of related miR-708 and miR-151, could contribute to MPN pathogenicity 3418 hsa-mir-708 Neoplasms 20445018 miR-708:down-modulating MPL and other targets of miR-28, and of related miR-708 and miR-151, could contribute to MPN pathogenicity 3419 hsa-mir-21 Carcinoma, Hepatocellular 20447717 microRNA-21:MicroRNA-21 acts as an oncomir through multiple targets in human hepatocellular carcinoma 3420 hsa-mir-18a Lymphoma, T-Cell 20448109 mir-18a:down-regulation of the miR-17-92 cluster in malignancy 3421 hsa-mir-19a Lymphoma, T-Cell 20448109 mir-19a:down-regulation of the miR-17-92 cluster in malignancy 3422 hsa-mir-19b-1 Lymphoma, T-Cell 20448109 mir-19b:down-regulation of the miR-17-92 cluster in malignancy 3423 hsa-mir-19b-2 Lymphoma, T-Cell 20448109 mir-19b:down-regulation of the miR-17-92 cluster in malignancy 3424 hsa-mir-20a Lymphoma, T-Cell 20448109 mir-20a:down-regulation of the miR-17-92 cluster in malignancy 3425 hsa-mir-92a-1 Lymphoma, T-Cell 20448109 mir-92a:down-regulation of the miR-17-92 cluster in malignancy 3426 hsa-mir-92a-2 Lymphoma, T-Cell 20448109 mir-92a:down-regulation of the miR-17-92 cluster in malignancy 3427 hsa-mir-20a Ovarian Neoplasms 20458444 miR-20a:miR-20a promotes proliferation and invasion by targeting APP in human ovarian cancer cells 3428 hsa-mir-199a-1 Cardiomegaly 20458739 miR-199a:miR-199a is essential for the maintenance of cell size in cardiomyocytes 3429 hsa-mir-199a-2 Cardiomegaly 20458739 miR-199a:miR-199a is essential for the maintenance of cell size in cardiomyocytes 3430 hsa-mir-199a-1 Myocytes, Cardiac 20458739 miR-199a is essential for the maintenance of cell size in cardiomyocytes 3431 hsa-mir-199a-2 Myocytes, Cardiac 20458739 miR-199a is essential for the maintenance of cell size in cardiomyocytes 3432 hsa-mir-21 Adenocarcinoma 20460539 miR-21:miR-21 expression correlated with outcome in PDAC patients treated with gemcitabine 3433 hsa-mir-221 Carcinoma 20461750 MiR-221:MiR-221 and MiR-222 alterations in sporadic ovarian carcinoma 3434 hsa-mir-222 Carcinoma 20461750 MiR-222:MiR-221 and MiR-222 alterations in sporadic ovarian carcinoma 3435 hsa-mir-31 Mesothelioma 20463022 miR-31:Pro-tumorigenic effects of miR-31 loss in mesothelioma 3436 hsa-mir-542 Neuroblastoma 20466808 miR-542-5p:the putative tumor suppressive microRNAs, miR-542-5p and miR-628, were expressed in favorable NBs and virtually absent in unfavorable NBs 3437 hsa-mir-628 Neuroblastoma 20466808 miR-628:the putative tumor suppressive microRNAs, miR-542-5p and miR-628, were expressed in favorable NBs and virtually absent in unfavorable NBs 3438 hsa-mir-195 Cardiomyopathy, Hypertrophic 20470752 miR-195:miR-23a, miR-27b, miR-125b and miR-195 were induced during early hypertrophic growth 3439 hsa-mir-23a Cardiomyopathy, Hypertrophic 20470752 miR-23a:miR-23a, miR-27b, miR-125b and miR-195 were induced during early hypertrophic growth 3440 hsa-mir-27b Cardiomyopathy, Hypertrophic 20470752 miR-27b:miR-23a, miR-27b, miR-125b and miR-195 were induced during early hypertrophic growth 3441 hsa-mir-301a Lung Neoplasms 20470754 miR-301:blocking of miR-301 in A549 cells leads to a decrease in the expression of the host gene, ska2 3442 hsa-mir-196a-1 Melanoma 20480203 miR-196a:MicroRNA miR-196a is a central regulator of HOX-B7 and BMP4 expression in malignant melanoma 3443 hsa-mir-196a-2 Melanoma 20480203 miR-196a:MicroRNA miR-196a is a central regulator of HOX-B7 and BMP4 expression in malignant melanoma 3444 hsa-mir-99a Adrenal Cortex Neoplasms 20484036 miR-99a:differentially regulated in childhood adrenocortical tumors (ACT), including miR-99a and miR-100 3445 hsa-mir-200a Carcinoma 20484038 miR-200a:Downregulation of microRNA-200 in EBV-associated gastric carcinoma 3446 hsa-mir-200b Carcinoma 20484038 miR-200b:Downregulation of microRNA-200 in EBV-associated gastric carcinoma 3447 hsa-mir-200c Carcinoma 20484038 miR-200c:Downregulation of microRNA-200 in EBV-associated gastric carcinoma 3448 hsa-mir-92a-1 Breast Neoplasms 20484043 miR-92:Estrogen receptor {beta}1 expression is regulated by miR-92 in breast cancer 3449 hsa-mir-92a-2 Breast Neoplasms 20484043 miR-92:Estrogen receptor {beta}1 expression is regulated by miR-92 in breast cancer 3450 hsa-mir-107 Heart Failure 20484156 miR-107: downregulated 3451 hsa-mir-139 Heart Failure 20484156 miR-139: downregulated 3452 hsa-mir-142 Heart Failure 20484156 miR-142-5p: downregulated 3453 hsa-mir-296 Carcinoma, Squamous Cell 20485139 miR-296:MiR-296 might play important roles in the pathogenesis of esophageal cancer and considered as a potential target for this malignancy intervention 3454 hsa-mir-20b Lymphoma, Mantle-Cell 20485376 miR-20b:miR-20b, whose lack of expression distinguished cases with a survival probability of 56% at 60 months 3455 hsa-mir-26a-1 Lymphoma, Mantle-Cell 20485376 miR-26a:NF-kappaB subunit nuclear translocation to be regulated by the expression of miR-26a 3456 hsa-mir-26a-2 Lymphoma, Mantle-Cell 20485376 miR-26a:NF-kappaB subunit nuclear translocation to be regulated by the expression of miR-26a 3457 hsa-mir-371a Lupus Nephritis 20485490 miR-371-5P:hsa-miR-371-5P, hsa-miR-423-5P, hsa-miR-638, hsa-miR-1224-3P and hsa-miR-663 that were differentially expressed in lupus nephritis across different racial groups and all specimen types tested 3458 hsa-mir-423 Lupus Nephritis 20485490 miR-423-5P:hsa-miR-371-5P, hsa-miR-423-5P, hsa-miR-638, hsa-miR-1224-3P and hsa-miR-663 that were differentially expressed in lupus nephritis across different racial groups and all specimen types tested 3459 hsa-mir-638 Lupus Nephritis 20485490 miR-638:hsa-miR-371-5P, hsa-miR-423-5P, hsa-miR-638, hsa-miR-1224-3P and hsa-miR-663 that were differentially expressed in lupus nephritis across different racial groups and all specimen types tested 3460 hsa-mir-663a Lupus Nephritis 20485490 miR-663:hsa-miR-371-5P, hsa-miR-423-5P, hsa-miR-638, hsa-miR-1224-3P and hsa-miR-663 that were differentially expressed in lupus nephritis across different racial groups and all specimen types tested 3461 hsa-mir-181a-1 Leukemia, Lymphocytic, Chronic, B-Cell 20487546 miR-181a:Differential expression of the sulfatase SULF2 and of miR-29a, -181a, and -221 was also observed between resistant and sensitive patients before treatment 3462 hsa-mir-181a-2 Leukemia, Lymphocytic, Chronic, B-Cell 20487546 miR-181a:Differential expression of the sulfatase SULF2 and of miR-29a, -181a, and -221 was also observed between resistant and sensitive patients before treatment 3463 hsa-mir-221 Leukemia, Lymphocytic, Chronic, B-Cell 20487546 miR-221:Differential expression of the sulfatase SULF2 and of miR-29a, -181a, and -221 was also observed between resistant and sensitive patients before treatment 3464 hsa-mir-29a Leukemia, Lymphocytic, Chronic, B-Cell 20487546 miR-29a:Differential expression of the sulfatase SULF2 and of miR-29a, -181a, and -221 was also observed between resistant and sensitive patients before treatment 3465 hsa-mir-206 Myotonic Dystrophy 20487562 microRNA-206:Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients 3466 hsa-mir-196a-2 Cardiomyopathy, Dilated 20488170 mir-196a2:Common genetic polymorphisms in pre-microRNAs were associated with increased risk of dilated cardiomyopathy 3467 hsa-mir-499a Cardiomyopathy, Dilated 20488170 mir-499:Common genetic polymorphisms in pre-microRNAs were associated with increased risk of dilated cardiomyopathy 3468 hsa-mir-27a Pancreatic Neoplasms 20488920 microRNA-27a:Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a 3469 hsa-mir-192 Fibrosis 20488955 miR-192:miR-192 mediates TGF-beta/Smad3-driven renal fibrosis 3470 hsa-mir-21 Coronary Artery Disease 20489163 miR-21:We identified a novel miR-21-dependent mechanism of ADMA-mediated APC dysfunction 3471 hsa-mir-21 Atherosclerosis 20489169 miR-21:found high levels of expression for all of them in quiescent endothelial cells 3472 hsa-mir-210 Atherosclerosis 20489169 miR-210:found high levels of expression for all of them in quiescent endothelial cells 3473 hsa-mir-221 Atherosclerosis 20489169 miR-221:found high levels of expression for all of them in quiescent endothelial cells 3474 hsa-mir-222 Atherosclerosis 20489169 miR-222:found high levels of expression for all of them in quiescent endothelial cells 3475 hsa-mir-296 Atherosclerosis 20489169 miR-296:found high levels of expression for all of them in quiescent endothelial cells 3476 hsa-mir-200a Carcinoma 20498632 miR-200a:altered microRNA signatures as potent markers for ATCs 3477 hsa-mir-200b Carcinoma 20498632 miR-200b:altered microRNA signatures as potent markers for ATCs 3478 hsa-mir-200c Carcinoma 20498632 miR-200c:altered microRNA signatures as potent markers for ATCs 3479 hsa-mir-21 Carcinoma 20498632 miR-21:altered microRNA signatures as potent markers for ATCs 3480 hsa-mir-30a Carcinoma 20498632 miR-30:altered microRNA signatures as potent markers for ATCs 3481 hsa-mir-30a Breast Neoplasms 20498642 Mir-30:Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells 3482 hsa-mir-21 Pancreatic Neoplasms 20498843 microRNA-21:Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer 3483 hsa-mir-199a-1 Carcinoma, Hepatocellular 20501828 MiR-199a-3p:MiR-199a-3p regulates mTOR and c-Met to influence the doxorubicin sensitivity of human hepatocarcinoma cells 3484 hsa-mir-199a-2 Carcinoma, Hepatocellular 20501828 MiR-199a-3p:MiR-199a-3p regulates mTOR and c-Met to influence the doxorubicin sensitivity of human hepatocarcinoma cells 3485 hsa-mir-520h Neoplasms 20501832 miR-520h:Downregulation of microRNA miR-520h by E1A contributes to anticancer activity 3486 hsa-mir-206 Rhabdomyosarcoma 20502458 MicroRNA-206:MicroRNA-206 expression levels correlate with clinical behaviour of rhabdomyosarcomas 3487 hsa-mir-21 Leukemia, Lymphocytic, Chronic, B-Cell 20504344 miR-21:miR-148a, miR-222 and miR-21 exhibited a significantly higher expression in non-responder patients 3488 hsa-mir-222 Leukemia, Lymphocytic, Chronic, B-Cell 20504344 miR-222:miR-148a, miR-222 and miR-21 exhibited a significantly higher expression in non-responder patients 3489 hsa-mir-331 Stomach Neoplasms 20510161 miRNA-331-3p:miRNA-331-3p directly targets E2F1 and induces growth arrest in human gastric cancer 3490 hsa-mir-200a Breast Neoplasms 20514023 miR-200a:Our results suggest that the miR-200 family has a tumor-suppressor function by negatively regulating EGF-driven cell invasion 3491 hsa-mir-200b Breast Neoplasms 20514023 miR-200b:Our results suggest that the miR-200 family has a tumor-suppressor function by negatively regulating EGF-driven cell invasion 3492 hsa-mir-200c Breast Neoplasms 20514023 mir-200c:Our results suggest that the miR-200 family has a tumor-suppressor function by negatively regulating EGF-driven cell invasion 3493 hsa-mir-21 Glioma 20514462 miR-21:Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3 3494 hsa-mir-92a-1 Carcinoma, Hepatocellular 20518884 miR-92a:Deregulation of miR-92a expression is implicated in hepatocellular carcinoma development 3495 hsa-mir-92a-2 Carcinoma, Hepatocellular 20518884 miR-92a:Deregulation of miR-92a expression is implicated in hepatocellular carcinoma development 3496 hsa-mir-25 Muscular Dystrophy, Facioscapulohumeral 20519410 miR-25:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence 3497 hsa-mir-32 Muscular Dystrophy, Facioscapulohumeral 20519410 miR-32:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence 3498 hsa-mir-363 Muscular Dystrophy, Facioscapulohumeral 20519410 miR-363:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence 3499 hsa-mir-367 Muscular Dystrophy, Facioscapulohumeral 20519410 miR-367:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence 3500 hsa-mir-92a-1 Muscular Dystrophy, Facioscapulohumeral 20519410 miR-92:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence 3501 hsa-mir-92a-2 Muscular Dystrophy, Facioscapulohumeral 20519410 miR-92:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence 3502 hsa-mir-206 Waldenstrom Macroglobulinemia 20519629 miR-206:Waldenstr?m macroglobulinemia (WM) cells present with increased expression of microRNA-206 (miRNA-206) and reduced expression of miRNA-9 3503 hsa-mir-9-1 Waldenstrom Macroglobulinemia 20519629 miR-9:Waldenstr?m macroglobulinemia (WM) cells present with increased expression of microRNA-206 (miRNA-206) and reduced expression of miRNA-9 3504 hsa-mir-9-2 Waldenstrom Macroglobulinemia 20519629 miR-9:Waldenstr?m macroglobulinemia (WM) cells present with increased expression of microRNA-206 (miRNA-206) and reduced expression of miRNA-9 3505 hsa-mir-26a-1 Hypertrophy 20525681 MiR-26a:stretch or enforced expression of miR-26a induces HASMC hypertrophy 3506 hsa-mir-26a-2 Hypertrophy 20525681 MiR-26a:stretch or enforced expression of miR-26a induces HASMC hypertrophy 3507 hsa-mir-222 Neoplasms 20525881 miR-222:five miRNAs that negatively control cell proliferation, including miRNA-34a 3508 hsa-mir-224 Neoplasms 20525881 miR-224:five miRNAs that negatively control cell proliferation, including miRNA-34a 3509 hsa-mir-29b-1 Neoplasms 20525881 miR-29b:five miRNAs that negatively control cell proliferation, including miRNA-34a 3510 hsa-mir-29b-2 Neoplasms 20525881 miR-29b:five miRNAs that negatively control cell proliferation, including miRNA-34a 3511 hsa-mir-34a Neoplasms 20525881 miR-34a:five miRNAs that negatively control cell proliferation, including miRNA-34a 3512 hsa-mir-532 Neoplasms 20525881 miR-532:five miRNAs that negatively control cell proliferation, including miRNA-34a 3513 hsa-mir-17 Melanoma 20529253 miR-17:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3514 hsa-mir-181a-2 Melanoma 20529253 miR-181a-2*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3515 hsa-mir-183 Melanoma 20529253 miR-183*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3516 hsa-mir-186 Melanoma 20529253 miR-186:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3517 hsa-mir-18a Melanoma 20529253 miR-18a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3518 hsa-mir-18a Melanoma 20529253 miR-18a*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3519 hsa-mir-199a-1 Melanoma 20529253 miR-199a-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3520 hsa-mir-199a-2 Melanoma 20529253 miR-199a-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3521 hsa-mir-20a Melanoma 20529253 miR-20a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3522 hsa-mir-20b Melanoma 20529253 miR-20b:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3523 hsa-mir-214 Melanoma 20529253 miR-214:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3524 hsa-mir-216a Melanoma 20529253 miR-216a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3525 hsa-mir-217 Melanoma 20529253 miR-217:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3526 hsa-mir-22 Melanoma 20529253 miR-22*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3527 hsa-mir-221 Melanoma 20529253 miR-221*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3528 hsa-mir-30a Melanoma 20529253 miR-30a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3529 hsa-mir-30e Melanoma 20529253 miR-30e*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3530 hsa-mir-328 Melanoma 20529253 miR-328:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3531 hsa-mir-330 Melanoma 20529253 miR-330-3p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3532 hsa-mir-342 Melanoma 20529253 miR-342-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3533 hsa-mir-361 Melanoma 20529253 miR-361-3p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3534 hsa-mir-362 Melanoma 20529253 miR-362-3p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3535 hsa-mir-362 Melanoma 20529253 miR-362-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3536 hsa-mir-365a Melanoma 20529253 miR-365:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3537 hsa-mir-365b Melanoma 20529253 miR-365:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3538 hsa-mir-378a Melanoma 20529253 miR-378*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3539 hsa-mir-422a Melanoma 20529253 miR-422a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3540 hsa-mir-452 Melanoma 20529253 miR-452:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3541 hsa-mir-501 Melanoma 20529253 miR-501-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3542 hsa-mir-509-3 Melanoma 20529253 miR-509-3-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3543 hsa-mir-517a Melanoma 20529253 miR-517*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3544 hsa-mir-518e Melanoma 20529253 miR-518e*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3545 hsa-mir-519b Melanoma 20529253 miR-519b-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3546 hsa-mir-550a-1 Melanoma 20529253 miR-550*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3547 hsa-mir-550a-2 Melanoma 20529253 miR-550*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3548 hsa-mir-584 Melanoma 20529253 miR-584:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3549 hsa-mir-593 Melanoma 20529253 miR-593*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3550 hsa-mir-621 Melanoma 20529253 miR-621:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3551 hsa-mir-625 Melanoma 20529253 miR-625:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3552 hsa-mir-646 Melanoma 20529253 miR-646:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3553 hsa-mir-664 Melanoma 20529253 miR-664:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3554 hsa-mir-767 Melanoma 20529253 miR-767-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3555 hsa-mir-99a Melanoma 20529253 miR-99a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients 3556 hsa-mir-31 Neoplasms 20530680 miR-31:Concurrent suppression of integrin alpha5, radixin, and RhoA phenocopies the effects of miR-31 on metastasis 3557 hsa-mir-661 Breast Neoplasms 20543867 miR-661:miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers 3558 hsa-mir-21 Heart Failure 20546595 We show that the transcription factor p53 piggy-backs onto NF-kappaB/RELA and utilizes the kappaB-motif at a cis-regulatory region to control mir-21 expression. 3559 hsa-mir-221 Melanoma 20547861 microRNA-221:Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells 3560 hsa-mir-375 Stomach Neoplasms 20548334 MiR-375:MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2 3561 hsa-mir-196b Leukemia, Lymphocytic, Chronic, B-Cell 20549547 miR-196b:Potential tumor suppressive function of miR-196b in B-cell lineage acute lymphoblastic leukemia 3562 hsa-mir-200a Pancreatic Neoplasms 20551052 miR-200a:The elevated serum levels of miR-200a and miR-200b in most patients with pancreatic cancer could have diagnostic utility 3563 hsa-mir-200b Pancreatic Neoplasms 20551052 miR-200b:The elevated serum levels of miR-200a and miR-200b in most patients with pancreatic cancer could have diagnostic utility 3564 hsa-mir-21 Cardiovascular Diseases 20560046 miR-21:miR-21 might be a novel therapeutic target in cardiovascular diseases 3565 hsa-mir-21 Heart Failure 20560046 miR-21 is found to play important roles in vascular smooth muscle cell proliferation and apoptosis, cardiac cell growth and death, and cardiac fibroblast functions 3566 hsa-mir-21 Vascular Diseases 20560046 miR-21 is found to play important roles in vascular smooth muscle cell proliferation and apoptosis, cardiac cell growth and death, and cardiac fibroblast functions 3567 hsa-mir-21 Myocardium 20560046 miR-21 is found to play important roles in vascular smooth muscle cell proliferation and apoptosis, cardiac cell growth and death, and cardiac fibroblast functions 3568 hsa-mir-21 Cardiomyopathy, Hypertrophic 20560046 miR-21 is found to play important roles in vascular smooth muscle cell proliferation and apoptosis, cardiac cell growth and death, and cardiac fibroblast functions 3569 hsa-mir-23b Kidney Neoplasms 20562915 miR-23b:miR-23b targets proline oxidase, a novel tumor suppressor protein in renal cancer 3570 hsa-mir-22 Neoplasms 20562918 miR-22:miR-22 acts as a tumor suppressor through direct repression of MYCBP expression and subsequent reduction of oncogenic c-Myc activities. 3571 hsa-mir-29a Leukemia, Lymphocytic, Chronic, B-Cell 20566844 miR-29:dysregulation of miR-29 can contribute to the pathogenesis of indolent B-CLL 3572 hsa-mir-34a Lung Neoplasms 20570894 miR-34a:Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34 3573 hsa-mir-542 Carcinoma, Squamous Cell 20574436 Expression of the most significant TrkA-correlated miRNA, miR-542-5p, also discriminated between local and metastatic disease and was inversely correlated with MYCN amplification and event-free survival. miR-542-5p might be important in neuroblastoma tumour biology, and qualify as potential therapeutic targets. 3574 hsa-mir-181a-1 Carcinoma, Hepatocellular 20576283 miRNA-181a:Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines 3575 hsa-mir-181a-2 Carcinoma, Hepatocellular 20576283 miRNA-181a:Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines 3576 hsa-mir-21 Colitis, Ulcerative 20586854 miR-21:Upregulated miRNA may be responsible for the development of intestinal inflammation in UC 3577 hsa-mir-185 Neoplasms 20603620 miRNA-185:MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers 3578 hsa-mir-96 Pancreatic Neoplasms 20610624 miRNA-96:miRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer 3579 hsa-mir-212 Cocaine-Related Disorders 20613834 miR-212:miR-212 signalling has a key role in determining vulnerability to cocaine addiction 3580 hsa-mir-206 Distal Myopathies 20619221 miR-206:have a profound influence on multiple myopathies 3581 hsa-mir-206 Hypertrophy 20619221 miR-206:have a profound influence on multiple myopathies 3582 hsa-mir-200c Carcinoma, Hepatocellular 20619223 miR-200c:Hsa-miR-141 and hsa-miR-200c, microRNAs that promote epithelial phenotypes, had significantly higher levels in non-hepatic epithelial tumors 3583 hsa-mir-126 Stomach Neoplasms 20619534 miR-126 functions as a tumour suppressor in human gastric cancer 3584 hsa-mir-185 Carcinoma, Squamous Cell 20620595 miR-185:The miRNAs miR-185 * and miR-125a-5p were significantly upregulated in lung SCC 3585 hsa-mir-193a Carcinoma, Squamous Cell 20620595 miR-193a-3p:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC 3586 hsa-mir-30a Carcinoma, Squamous Cell 20620595 miR-30a:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC 3587 hsa-mir-30d Carcinoma, Squamous Cell 20620595 miR-30d:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC 3588 hsa-mir-21 Colorectal Neoplasms 20620599 miR-21:Our results support the hypothesis about oncogenic function of miR-21 3589 hsa-mir-301a Lung Neoplasms 20624269 miR-301:we found significant overexpression of miR-103, miR-107, miR-301 and miR-338 in lung cancer cells as compared to HBECs 3590 hsa-mir-338 Lung Neoplasms 20624269 miR-338:we found significant overexpression of miR-103, miR-107, miR-301 and miR-338 in lung cancer cells as compared to HBECs 3591 hsa-mir-27a Ovarian Neoplasms 20624637 MiR-27a:MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells 3592 hsa-mir-186 Lung Neoplasms 20627087 miR-186:miR-186 * may serve as a potential gene therapy target for refractory lung cancer that is sensitive to curcumin 3593 hsa-mir-34a Atherosclerosis 20627091 MiR-34a:MicroRNA-34a regulation of endothelial senescence 3594 hsa-mir-34a Cardiovascular Diseases 20627091 MiR-34a:MicroRNA-34a regulation of endothelial senescence 3595 hsa-mir-320a Ischemia 20628061 MicroRNA 320a functions as a novel endogenous modulator of aquaporins 1 and 4 as well as a potential therapeutic target in cerebral ischemia 3596 hsa-mir-520h Pancreatic Neoplasms 20628378 miR-520h:miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion, and side populations 3597 hsa-mir-29a Leukemia, Myeloid, Acute 20628397 miR-29a:The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML 3598 hsa-mir-29b-1 Leukemia, Myeloid, Acute 20628397 miR-29b1:The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML 3599 hsa-mir-181b-1 Adenoviridae Infections 20634878 miR-181b-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3600 hsa-mir-181b-2 Adenoviridae Infections 20634878 miR-181b-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3601 hsa-mir-18a Adenoviridae Infections 20634878 miR-18a:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3602 hsa-mir-18b Adenoviridae Infections 20634878 miR-18b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3603 hsa-mir-191 Adenoviridae Infections 20634878 miR-191:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3604 hsa-mir-196b Adenoviridae Infections 20634878 miR-196b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3605 hsa-mir-1972-1 Adenoviridae Infections 20634878 miR-1972:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3606 hsa-mir-19b-1 Adenoviridae Infections 20634878 miR-19b-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3607 hsa-mir-19b-2 Adenoviridae Infections 20634878 miR-19b-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3608 hsa-mir-210 Adenoviridae Infections 20634878 miR-210:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3609 hsa-mir-219-1 Adenoviridae Infections 20634878 miR-219-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3610 hsa-mir-25 Adenoviridae Infections 20634878 miR-25:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3611 hsa-mir-26b Adenoviridae Infections 20634878 miR-26b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3612 hsa-mir-27a Adenoviridae Infections 20634878 miR-27a:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3613 hsa-mir-27b Adenoviridae Infections 20634878 miR-27b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3614 hsa-mir-30a Adenoviridae Infections 20634878 miR-30a:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3615 hsa-mir-30b Adenoviridae Infections 20634878 miR-30b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3616 hsa-mir-30c-1 Adenoviridae Infections 20634878 miR-30c-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3617 hsa-mir-30c-2 Adenoviridae Infections 20634878 miR-30c-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3618 hsa-mir-320c-2 Adenoviridae Infections 20634878 miR-320c-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3619 hsa-mir-324 Adenoviridae Infections 20634878 miR-324:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3620 hsa-mir-338 Adenoviridae Infections 20634878 miR-338:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3621 hsa-mir-33a Adenoviridae Infections 20634878 miR-33a:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3622 hsa-mir-342 Adenoviridae Infections 20634878 miR-342:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3623 hsa-mir-345 Adenoviridae Infections 20634878 miR-345:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3624 hsa-mir-34a Adenoviridae Infections 20634878 miR-34a:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3625 hsa-mir-362 Adenoviridae Infections 20634878 miR-362:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3626 hsa-mir-374b Adenoviridae Infections 20634878 miR-374b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3627 hsa-mir-378a Adenoviridae Infections 20634878 miR-378:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3628 hsa-mir-421 Adenoviridae Infections 20634878 miR-421:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3629 hsa-mir-433 Adenoviridae Infections 20634878 miR-433:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3630 hsa-mir-452 Adenoviridae Infections 20634878 miR-452:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3631 hsa-mir-454 Adenoviridae Infections 20634878 miR-454:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3632 hsa-mir-505 Adenoviridae Infections 20634878 miR-505:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3633 hsa-mir-519a-1 Adenoviridae Infections 20634878 miR-519a-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3634 hsa-mir-566 Adenoviridae Infections 20634878 miR-566:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3635 hsa-mir-582 Adenoviridae Infections 20634878 miR-582:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3636 hsa-mir-589 Adenoviridae Infections 20634878 miR-589:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3637 hsa-mir-619 Adenoviridae Infections 20634878 miR-619:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3638 hsa-mir-627 Adenoviridae Infections 20634878 miR-627:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3639 hsa-mir-635 Adenoviridae Infections 20634878 miR-635:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3640 hsa-mir-650 Adenoviridae Infections 20634878 miR-650:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3641 hsa-mir-655 Adenoviridae Infections 20634878 miR-655:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3642 hsa-mir-7-1 Adenoviridae Infections 20634878 miR-7-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3643 hsa-mir-7-2 Adenoviridae Infections 20634878 miR-7-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3644 hsa-mir-7-3 Adenoviridae Infections 20634878 miR-7-3:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3645 hsa-mir-744 Adenoviridae Infections 20634878 miR-744:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3646 hsa-mir-92a-1 Adenoviridae Infections 20634878 miR-92a-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3647 hsa-mir-92a-2 Adenoviridae Infections 20634878 miR-92a-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3648 hsa-mir-942 Adenoviridae Infections 20634878 miR-942:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control 3649 hsa-mir-21 Pulmonary Fibrosis 20643828 miR-21:These experiments demonstrate an important role for miR-21 in fibrotic lung diseases 3650 hsa-mir-187 Reperfusion Injury 20651252 miR-187:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI 3651 hsa-mir-192 Reperfusion Injury 20651252 miR-192:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI 3652 hsa-mir-194-1 Reperfusion Injury 20651252 miR-194:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI 3653 hsa-mir-194-2 Reperfusion Injury 20651252 miR-194:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI 3654 hsa-mir-199a-1 Reperfusion Injury 20651252 miR-199a-3p:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI 3655 hsa-mir-199a-2 Reperfusion Injury 20651252 miR-199a-3p:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI 3656 hsa-mir-20a Reperfusion Injury 20651252 miR-20a:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI 3657 hsa-mir-21 Reperfusion Injury 20651252 miR-21:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI 3658 hsa-mir-214 Reperfusion Injury 20651252 miR-214:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI 3659 hsa-mir-486 Diabetes Mellitus, Type 2 20651284 decreased in plasma 3660 hsa-mir-20b Diabetes Mellitus, Type 2 20651284 decreased in plasma 3661 hsa-mir-21 Diabetes Mellitus, Type 2 20651284 decreased in plasma 3662 hsa-mir-24-1 Diabetes Mellitus, Type 2 20651284 decreased in plasma 3663 hsa-mir-24-2 Diabetes Mellitus, Type 2 20651284 decreased in plasma 3664 hsa-mir-15a Diabetes Mellitus, Type 2 20651284 decreased in plasma 3665 hsa-mir-126 Diabetes Mellitus, Type 2 20651284 decreased in plasma 3666 hsa-mir-191 Diabetes Mellitus, Type 2 20651284 decreased in plasma 3667 hsa-mir-197 Diabetes Mellitus, Type 2 20651284 decreased in plasma 3668 hsa-mir-223 Diabetes Mellitus, Type 2 20651284 decreased in plasma 3669 hsa-mir-320a Diabetes Mellitus, Type 2 20651284 decreased in plasma 3670 hsa-mir-29a Breast Neoplasms 20664596 miR-29a:We identified a set of 13 miRNAs of which expression differed between IBC and non-IBC, making these miRNAs candidate markers for the IBC subtype 3671 hsa-mir-30b Breast Neoplasms 20664596 miR-30b:We identified a set of 13 miRNAs of which expression differed between IBC and non-IBC, making these miRNAs candidate markers for the IBC subtype 3672 hsa-mir-342 Breast Neoplasms 20664596 miR-342-3p:We identified a set of 13 miRNAs of which expression differed between IBC and non-IBC, making these miRNAs candidate markers for the IBC subtype 3673 hsa-mir-520a Breast Neoplasms 20664596 miR-520a-5p:We identified a set of 13 miRNAs of which expression differed between IBC and non-IBC, making these miRNAs candidate markers for the IBC subtype 3674 hsa-mir-27a Stomach Neoplasms 20666778 mir-27a:mir-27a genetic variant contributes to gastric cancer susceptibility 3675 hsa-mir-326 Glioma 20667897 Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells 3676 hsa-mir-34a Prostatic Neoplasms 20687223 MiR-34a:MiR-34a attenuates paclitaxel-resistance of hormone-refractory prostate cancer PC3 cells through direct and indirect mechanisms 3677 hsa-mir-21 Lymphoma, B-Cell 20693987 miR-21:OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma 3678 hsa-mir-206 Rhabdomyosarcoma 20696132 miR-206:miR-206, as landmark biomarkers for RMS 3679 hsa-mir-489 Carcinoma, Squamous Cell 20700123 miR-489:miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma 3680 hsa-mir-212 Cocaine-Related Disorders 20711185 miR-212:miR-212 in dorsal striatum may be important in regulating vulnerability to cocaine addiction 3681 hsa-mir-335 Neoplasms 20713524 miR-335:miR-335 activates the p53 tumor suppressor pathway to limit cell proliferation and neoplastic cell transformation 3682 hsa-mir-103a-1 Stomach Neoplasms 20726036 miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers 3683 hsa-mir-103a-2 Stomach Neoplasms 20726036 miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers 3684 hsa-mir-21 Stomach Neoplasms 20726036 miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers 3685 hsa-mir-145 Stomach Neoplasms 20726036 miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers 3686 hsa-mir-106b Stomach Neoplasms 20726036 miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers 3687 hsa-mir-146a Stomach Neoplasms 20726036 miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers 3688 hsa-mir-148a Stomach Neoplasms 20726036 miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers 3689 hsa-mir-195 Colorectal Neoplasms 20727858 miR-195:microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells 3690 hsa-mir-10b Nasopharyngeal Neoplasms 20732742 MicroRNA-10b induced by Epstein-Barr virus-encoded latent membrane protein-1 promotes the metastasis of human nasopharyngeal carcinoma cells 3691 hsa-mir-181b-1 Inflammation 20797623 miR-181b-1:STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer 3692 hsa-mir-181b-1 Neoplasms 20797623 miR-181b-1:STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer 3693 hsa-mir-21 Inflammation 20797623 miR-21:STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer 3694 hsa-mir-21 Neoplasms 20797623 miR-21:STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer 3695 hsa-mir-18a Lymphoma, Large-Cell, Anaplastic 20805506 miR-18a:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL 3696 hsa-mir-19a Lymphoma, Large-Cell, Anaplastic 20805506 miR-19a:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL 3697 hsa-mir-19b-1 Lymphoma, Large-Cell, Anaplastic 20805506 miR-19b:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL 3698 hsa-mir-19b-2 Lymphoma, Large-Cell, Anaplastic 20805506 miR-19b:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL 3699 hsa-mir-20a Lymphoma, Large-Cell, Anaplastic 20805506 miR-20a:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL 3700 hsa-mir-92a-1 Lymphoma, Large-Cell, Anaplastic 20805506 miR-92a:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL 3701 hsa-mir-92a-2 Lymphoma, Large-Cell, Anaplastic 20805506 miR-92a:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL 3702 hsa-mir-1-1 Laryngeal Neoplasms 20806854 downregulated by 5 multiple 3703 hsa-mir-1-2 Laryngeal Neoplasms 20806854 downregulated by 5 multiple 3704 hsa-mir-486 Laryngeal Neoplasms 20806854 miR-486-5p: downregulated by 5 multiple 3705 hsa-mir-206 Laryngeal Neoplasms 20806854 downregulated by 5 multiple 3706 hsa-mir-487a Laryngeal Neoplasms 20806854 downregulated by 5 multiple 3707 hsa-mir-375 Laryngeal Neoplasms 20806854 downregulated by 5 multiple 3708 hsa-mir-422a Laryngeal Neoplasms 20806854 downregulated by 5 multiple 3709 hsa-mir-144 Laryngeal Neoplasms 20806854 downregulated by 5 multiple 3710 hsa-mir-384 Laryngeal Neoplasms 20806854 downregulated by 5 multiple 3711 hsa-mir-378a Laryngeal Neoplasms 20806854 downregulated by 5 multiple 3712 hsa-mir-133a-1 Laryngeal Neoplasms 20806854 downregulated by 5 multiple 3713 hsa-mir-133a-2 Laryngeal Neoplasms 20806854 downregulated by 5 multiple 3714 hsa-mir-93 Laryngeal Neoplasms 20806854 upregulated by 3 multiple 3715 hsa-mir-31 Laryngeal Neoplasms 20806854 upregulated by 3 multiple 3716 hsa-mir-20b Laryngeal Neoplasms 20806854 upregulated by 3 multiple 3717 hsa-let-7a-1 Spinal Cord Injuries 20816819 spinal cord injury (SCI)results in increased expression of miR Let-7a and miR16 while exercise leads to elevated levels of miR21 and decreased levels of miR15b. These changes in miR expression are correlated with changes in expression of their target genes: pro-apoptotic (decreased PTEN, PDCD4, and RAS mRNA) and anti-apoptotic (increased Bcl-2 mRNA) target genes. This is accompanied by a down-regulation of mRNA for caspase-7 and caspase-9 and reduced levels of caspase-7 protein. 3718 hsa-let-7a-2 Spinal Cord Injuries 20816819 spinal cord injury (SCI)results in increased expression of miR Let-7a and miR16 while exercise leads to elevated levels of miR21 and decreased levels of miR15b. These changes in miR expression are correlated with changes in expression of their target genes: pro-apoptotic (decreased PTEN, PDCD4, and RAS mRNA) and anti-apoptotic (increased Bcl-2 mRNA) target genes. This is accompanied by a down-regulation of mRNA for caspase-7 and caspase-9 and reduced levels of caspase-7 protein. 3719 hsa-let-7a-3 Spinal Cord Injuries 20816819 spinal cord injury (SCI)results in increased expression of miR Let-7a and miR16 while exercise leads to elevated levels of miR21 and decreased levels of miR15b. These changes in miR expression are correlated with changes in expression of their target genes: pro-apoptotic (decreased PTEN, PDCD4, and RAS mRNA) and anti-apoptotic (increased Bcl-2 mRNA) target genes. This is accompanied by a down-regulation of mRNA for caspase-7 and caspase-9 and reduced levels of caspase-7 protein. 3720 hsa-mir-15b Spinal Cord Injuries 20816819 spinal cord injury (SCI)results in increased expression of miR Let-7a and miR16 while exercise leads to elevated levels of miR21 and decreased levels of miR15b. These changes in miR expression are correlated with changes in expression of their target genes: pro-apoptotic (decreased PTEN, PDCD4, and RAS mRNA) and anti-apoptotic (increased Bcl-2 mRNA) target genes. This is accompanied by a down-regulation of mRNA for caspase-7 and caspase-9 and reduced levels of caspase-7 protein. 3721 hsa-mir-16-1 Spinal Cord Injuries 20816819 spinal cord injury (SCI)results in increased expression of miR Let-7a and miR16 while exercise leads to elevated levels of miR21 and decreased levels of miR15b. These changes in miR expression are correlated with changes in expression of their target genes: pro-apoptotic (decreased PTEN, PDCD4, and RAS mRNA) and anti-apoptotic (increased Bcl-2 mRNA) target genes. This is accompanied by a down-regulation of mRNA for caspase-7 and caspase-9 and reduced levels of caspase-7 protein. 3722 hsa-mir-16-2 Spinal Cord Injuries 20816819 spinal cord injury (SCI)results in increased expression of miR Let-7a and miR16 while exercise leads to elevated levels of miR21 and decreased levels of miR15b. These changes in miR expression are correlated with changes in expression of their target genes: pro-apoptotic (decreased PTEN, PDCD4, and RAS mRNA) and anti-apoptotic (increased Bcl-2 mRNA) target genes. This is accompanied by a down-regulation of mRNA for caspase-7 and caspase-9 and reduced levels of caspase-7 protein. 3723 hsa-mir-21 Spinal Cord Injuries 20816819 spinal cord injury (SCI)results in increased expression of miR Let-7a and miR16 while exercise leads to elevated levels of miR21 and decreased levels of miR15b. These changes in miR expression are correlated with changes in expression of their target genes: pro-apoptotic (decreased PTEN, PDCD4, and RAS mRNA) and anti-apoptotic (increased Bcl-2 mRNA) target genes. This is accompanied by a down-regulation of mRNA for caspase-7 and caspase-9 and reduced levels of caspase-7 protein. 3724 hsa-mir-24-1 Carcinoma, Squamous Cell 20816961 miR-24:MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma 3725 hsa-mir-24-2 Carcinoma, Squamous Cell 20816961 miR-24:MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma 3726 hsa-mir-200a Neoplasms 20832727 miR-200a:Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells 3727 hsa-mir-200b Neoplasms 20832727 miR-200b:Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells 3728 hsa-mir-200c Neoplasms 20832727 miR-200c:Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells 3729 hsa-mir-21 Carcinoma, Non-Small-Cell Lung 20832755 miR-21:Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21 3730 hsa-mir-494 Ischemia 20837890 miR-494:MicroRNA-494 targeting both proapoptotic and antiapoptotic proteins protects against ischemia/reperfusion-induced cardiac injury 3731 hsa-mir-494 Reperfusion Injury 20837890 miR-494:MicroRNA-494 targeting both proapoptotic and antiapoptotic proteins protects against ischemia/reperfusion-induced cardiac injury 3732 hsa-mir-210 Myocardial Infarction 20837903 miR-210:MicroRNA-210 can improve angiogenesis, inhibit apoptosis, and improve cardiac function in a murine model of myocardial infarction. 3733 hsa-mir-195 Aortic Valve Insufficiency 20845893 miR-195:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI. 3734 hsa-mir-195 Aortic Valve Stenosis 20845893 miR-195:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI. 3735 hsa-mir-195 Heart Defects, Congenital 20845893 miR-195:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI. 3736 hsa-mir-26a-1 Aortic Valve Insufficiency 20845893 MiR-26a:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI. 3737 hsa-mir-26a-1 Aortic Valve Stenosis 20845893 MiR-26a:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI. 3738 hsa-mir-26a-1 Heart Defects, Congenital 20845893 MiR-26a:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI. 3739 hsa-mir-26a-2 Aortic Valve Insufficiency 20845893 MiR-26a:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI. 3740 hsa-mir-26a-2 Aortic Valve Stenosis 20845893 MiR-26a:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI. 3741 hsa-mir-26a-2 Heart Defects, Congenital 20845893 MiR-26a:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI. 3742 hsa-mir-30b Aortic Valve Insufficiency 20845893 MiR-30b:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI. 3743 hsa-mir-30b Aortic Valve Stenosis 20845893 MiR-30b:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI. 3744 hsa-mir-30b Heart Defects, Congenital 20845893 MiR-30b:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI. 3745 hsa-mir-21 Neuroma, Acoustic 20856158 miR-21:Elevated levels of hsa-microRNA-21 (miR-21) in vestibular schwannomas (VSs) may contribute to tumor growth by downregulating the tumor suppressor phosphatase and tensin homolog (PTEN) and consequent hyperactivation of protein kinase B 3746 hsa-mir-205 Colonic Neoplasms 20859756 miR-205:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3747 hsa-mir-365a Colonic Neoplasms 20859756 miR-365:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3748 hsa-mir-365b Colonic Neoplasms 20859756 miR-365:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3749 hsa-mir-449a Colonic Neoplasms 20859756 miR-449:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3750 hsa-mir-518c Colonic Neoplasms 20859756 miR-518c:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3751 hsa-mir-552 Colonic Neoplasms 20859756 miR-552:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3752 hsa-mir-584 Colonic Neoplasms 20859756 miR-584:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3753 hsa-mir-615 Colonic Neoplasms 20859756 miR-615:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3754 hsa-mir-622 Colonic Neoplasms 20859756 miR-622:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3755 hsa-mir-630 Colonic Neoplasms 20859756 miR-630:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection. 3756 hsa-mir-223 Leukemia, Lymphocytic, Chronic, B-Cell 20862275 miR-223:ZAP70, LPL, CLLU1, microRNA-29c and microRNA-223 were measured by real time PCR in a cohort of 170 patients 3757 hsa-mir-29c Leukemia, Lymphocytic, Chronic, B-Cell 20862275 miR-29c:ZAP70, LPL, CLLU1, microRNA-29c and microRNA-223 were measured by real time PCR in a cohort of 170 patients 3758 hsa-mir-192 Carcinoma 20864637 miR-192:Hsa-miR-193-3p was overexpressed in MPM, while hsa-miR-200c and hsa-miR-192 were overexpressed in peripheral lung adenocarcinoma and carcinomas 3759 hsa-mir-193a Mesothelioma 20864637 miR-193-3p:Hsa-miR-193-3p was overexpressed in MPM, while hsa-miR-200c and hsa-miR-192 were overexpressed in peripheral lung adenocarcinoma and carcinomas 3760 hsa-mir-200c Adenocarcinoma 20864637 miR-200c:Hsa-miR-193-3p was overexpressed in MPM, while hsa-miR-200c and hsa-miR-192 were overexpressed in peripheral lung adenocarcinoma and carcinomas 3761 hsa-mir-486 Autistic Disorder 20868653 miR-486:deregulated 3762 hsa-mir-181b-1 Autistic Disorder 20868653 miR-181b:deregulated 3763 hsa-mir-22 Ovarian Neoplasms 20869762 miR-22:miR-22 might be involved in inhibiting ovarian cancer metastasis 3764 hsa-mir-486 Colorectal Neoplasms 20881268 miR-146b-3p and miR-486-5p are more abundant in KRAS mutated samples after cetuximab treatment respect to wild-type ones 3765 hsa-mir-146b Colorectal Neoplasms 20881268 miR-146b-3p and miR-486-5p are more abundant in KRAS mutated samples after cetuximab treatment respect to wild-type ones 3766 hsa-mir-208b Myocardial Infarction 20921333 miRs-208b and -499 were highly elevated in acute myocardial infarction plasma 3767 hsa-mir-499a Heart Failure 20921333 miR-499 was significantly elevated 3768 hsa-mir-499a Myocardial Infarction 20921333 miRs-208b and -499 were highly elevated in acute myocardial infarction plasma 3769 hsa-mir-208b Myocarditis 20921333 a milder but significant elevation of miRs-208b and -499 were highly elevated in Viral Myocarditis plasma 3770 hsa-mir-499a Myocarditis 20921333 a milder but significant elevation of miRs-208b and -499 were highly elevated in Viral Myocarditis plasma 3771 hsa-mir-192 Multiple Myeloma 20951946 Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development 3772 hsa-mir-194-1 Multiple Myeloma 20951946 Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development 3773 hsa-mir-194-2 Multiple Myeloma 20951946 Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development 3774 hsa-mir-215 Multiple Myeloma 20951946 Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development 3775 hsa-mir-199a-1 Heart Failure 20965886 Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart 3776 hsa-mir-199a-2 Heart Failure 20965886 Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart 3777 hsa-mir-331 Leukemia 21070600 Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia. 3778 hsa-mir-27a Leukemia 21070600 Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia. 3779 hsa-mir-199b Heart Failure 21102440 miR-199b is a direct calcineurin/NFAT target gene that increases in expression in mouse and human heart failure, and targets the nuclear NFAT kinase dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a (Dyrk1a) 3780 hsa-mir-491 Colorectal Neoplasms 21128281 deleted 3781 hsa-mir-646 Colorectal Neoplasms 21128281 deleted 3782 hsa-mir-29a Scleroderma, Systemic 21129921 Circulating miR-29a levels in patients with scleroderma spectrum disorder 3783 hsa-mir-29a Scleroderma, Localized 21129921 Circulating miR-29a levels in patients with scleroderma spectrum disorder 3784 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 21130495 Downregulation 3785 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 21130495 Downregulation 3786 hsa-mir-29b-1 Leukemia, Lymphocytic, Chronic, B-Cell 21130495 Downregulation 3787 hsa-mir-29b-2 Leukemia, Lymphocytic, Chronic, B-Cell 21130495 Downregulation 3788 hsa-mir-181a-1 Leukemia, Lymphocytic, Chronic, B-Cell 21130495 Downregulation 3789 hsa-mir-181a-2 Leukemia, Lymphocytic, Chronic, B-Cell 21130495 Downregulation 3790 hsa-mir-181b-1 Leukemia, Lymphocytic, Chronic, B-Cell 21130495 Downregulation 3791 hsa-mir-181b-2 Leukemia, Lymphocytic, Chronic, B-Cell 21130495 Downregulation 3792 hsa-mir-21 Breast Neoplasms 21131358 Induction of MIR-21 by retinoic acid in estrogen-receptor-positive breast carcinoma cells: biological correlates and molecular targets 3793 hsa-mir-221 Gastrointestinal Neoplasms 21132270 Down-regulation of miR-221 and miR-222 correlates with pronounced Kit expression in gastrointestinal stromal tumors 3794 hsa-mir-222 Gastrointestinal Neoplasms 21132270 Down-regulation of miR-221 and miR-222 correlates with pronounced Kit expression in gastrointestinal stromal tumors 3795 hsa-mir-1-1 Urinary Bladder Neoplasms 21133599 dysregulated 3796 hsa-mir-1-2 Urinary Bladder Neoplasms 21133599 dysregulated 3797 hsa-mir-145 Urinary Bladder Neoplasms 21133599 dysregulated 3798 hsa-mir-143 Urinary Bladder Neoplasms 21133599 dysregulated 3799 hsa-mir-133a-1 Urinary Bladder Neoplasms 21133599 dysregulated 3800 hsa-mir-133a-2 Urinary Bladder Neoplasms 21133599 dysregulated 3801 hsa-mir-133b Urinary Bladder Neoplasms 21133599 dysregulated 3802 hsa-mir-125b-1 Urinary Bladder Neoplasms 21133599 dysregulated 3803 hsa-mir-125b-2 Urinary Bladder Neoplasms 21133599 dysregulated 3804 hsa-mir-200b Urinary Bladder Neoplasms 21133599 dysregulated 3805 hsa-mir-708 Urinary Bladder Neoplasms 21133599 dysregulated 3806 hsa-mir-99a Urinary Bladder Neoplasms 21133599 dysregulated 3807 hsa-mir-99b Urinary Bladder Neoplasms 21133599 dysregulated 3808 hsa-mir-9-1 Urinary Bladder Neoplasms 21138856 hypermethylation was more frequent and dense in CpG shores than islands 3809 hsa-mir-9-2 Urinary Bladder Neoplasms 21138856 hypermethylation was more frequent and dense in CpG shores than islands 3810 hsa-mir-9-3 Urinary Bladder Neoplasms 21138856 hypermethylation was more frequent and dense in CpG shores than islands 3811 hsa-mir-149 Urinary Bladder Neoplasms 21138856 hypermethylation was more frequent and dense in CpG shores than islands 3812 hsa-mir-210 Urinary Bladder Neoplasms 21138856 hypermethylation was more frequent and dense in CpG shores than islands 3813 hsa-mir-212 Urinary Bladder Neoplasms 21138856 hypermethylation was more frequent and dense in CpG shores than islands 3814 hsa-mir-328 Urinary Bladder Neoplasms 21138856 hypermethylation was more frequent and dense in CpG shores than islands 3815 hsa-mir-503 Urinary Bladder Neoplasms 21138856 hypermethylation was more frequent and dense in CpG shores than islands 3816 hsa-mir-1224 Urinary Bladder Neoplasms 21138856 hypermethylation was more frequent and dense in CpG shores than islands 3817 hsa-mir-1227 Urinary Bladder Neoplasms 21138856 hypermethylation was more frequent and dense in CpG shores than islands 3818 hsa-mir-1229 Urinary Bladder Neoplasms 21138856 hypermethylation was more frequent and dense in CpG shores than islands 3819 hsa-mir-296 Prostatic Neoplasms 21138859 Regulation of HMGA1 expression by microRNA296 affects prostate cancer growth and invasion 3820 hsa-mir-373 Prostatic Neoplasms 21139802 The oncogenic mi-croRNAs, miR-373 and miR-520c interact with CD44 in Prostate Cancer 3821 hsa-mir-520c Prostatic Neoplasms 21139802 The oncogenic mi-croRNAs, miR-373 and miR-520c interact with CD44 in Prostate Cancer 3822 hsa-mir-21 Pancreatic Neoplasms 21139804 upregulated and correlated with worse survival 3823 hsa-let-7d Pancreatic Neoplasms 21139804 downregulated 3824 hsa-mir-146a Pancreatic Neoplasms 21139804 downregulated 3825 hsa-mir-17 Breast Neoplasms 21140207 SNP (rs3739008) located at 3'UTR of NPAS2 and the C to T changing of the SNP may disrupt the binding of microRNA- (miR-)17-5p and miR-519e to the 3'UTR of NPAS2 3826 hsa-mir-519e Breast Neoplasms 21140207 SNP (rs3739008) located at 3'UTR of NPAS2 and the C to T changing of the SNP may disrupt the binding of microRNA- (miR-)17-5p and miR-519e to the 3'UTR of NPAS2 3827 hsa-let-7e Sarcoma, Synovial 21140508 upregulated 3828 hsa-mir-99b Sarcoma, Synovial 21140508 upregulated 3829 hsa-mir-125a Sarcoma, Synovial 21140508 miR-125a-3p: upregulated 3830 hsa-mir-128-1 Neuroblastoma 21143953 Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells. 3831 hsa-mir-128-2 Neuroblastoma 21143953 Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells. 3832 hsa-mir-17 Neuroblastoma 21145484 The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma. 3833 hsa-mir-18a Neuroblastoma 21145484 The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma. 3834 hsa-mir-19a Neuroblastoma 21145484 The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma. 3835 hsa-mir-19b-1 Neuroblastoma 21145484 The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma. 3836 hsa-mir-20a Neuroblastoma 21145484 The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma. 3837 hsa-mir-92a-1 Neuroblastoma 21145484 The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma. 3838 hsa-mir-145 Hepatoblastoma 21145831 downregulated in early stages of HBV-associated multistep hepatocarcinogenesis. 3839 hsa-mir-199b Hepatoblastoma 21145831 downregulated in early stages of HBV-associated multistep hepatocarcinogenesis. 3840 hsa-mir-199b Hepatoblastoma 21145831 upregulated in early stages of HBV-associated multistep hepatocarcinogenesis. 3841 hsa-let-7a-1 Prostatic Neoplasms 21148031 RPS2 control let-7a expression in human prostate cancer. 3842 hsa-mir-92a-1 Esophageal Neoplasms 21148309 microRNA-92a promotes lymph node metastasis of human esophageal squamous cell carcinoma via E-cadherin. 3843 hsa-mir-92a-2 Esophageal Neoplasms 21148309 microRNA-92a promotes lymph node metastasis of human esophageal squamous cell carcinoma via E-cadherin. 3844 hsa-mir-34a Myelodysplastic Syndromes 21150891 In early MDS, we monitored upregulation of proapoptotic miR-34a 3845 hsa-mir-326 Multiple Sclerosis 21151203 The expression of miRNA-326 in blood cells has been reported to increase during relapses. 3846 hsa-mir-21 Brain Injuries 21154462 miR-21 expression is significantly up-regulated in the hippocampus after rodent Traumatic brain injury 3847 hsa-mir-223 Liver Neoplasms 21154767 in serum, miR-21, miR-122, and miR-223 were significantly higher in patients with HCC than those in healthy controls 3848 hsa-mir-122 Liver Neoplasms 21154767 in serum, miR-21, miR-122, and miR-223 were significantly higher in patients with HCC than those in healthy controls 3849 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 21156224 often absent 3850 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 21156224 often absent 3851 hsa-mir-7-1 Neurilemmoma 21156648 miRNA-7 attenuation in schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways. 3852 hsa-mir-7-2 Neurilemmoma 21156648 miRNA-7 attenuation in schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways. 3853 hsa-mir-7-3 Neurilemmoma 21156648 miRNA-7 attenuation in schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways. 3854 hsa-mir-126 Heart Failure 21157109 The plasma concentration of miR-126 was negatively correlated with age and NYHA class, and could be a useful biomarker for heart failure 3855 hsa-mir-129-1 Brain Neoplasms 21157891 MicroRNA-129, miR-142-5p, and miR-25 were differ entially expressed in every pediatric brain tumor type compared to normal tissue controls as measured by microarray. 3856 hsa-mir-129-2 Brain Neoplasms 21157891 MicroRNA-129, miR-142-5p, and miR-25 were differ entially expressed in every pediatric brain tumor type compared to normal tissue controls as measured by microarray. 3857 hsa-mir-206 Lung Neoplasms 21157919 MicroRNA-206 Is Associated With Invasion and Metastasis of Lung Cancer. 3858 hsa-mir-218-1 Carcinoma, Non-Small-Cell Lung 21159652 Paxillin Predicts Survival and Relapse in Non-Small Cell Lung Cancer by MicroRNA-218 Targeting. 3859 hsa-mir-218-2 Carcinoma, Non-Small-Cell Lung 21159652 Paxillin Predicts Survival and Relapse in Non-Small Cell Lung Cancer by MicroRNA-218 Targeting. 3860 hsa-mir-143 Pancreatic Neoplasms 21159815 Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. 3861 hsa-mir-145 Pancreatic Neoplasms 21159815 Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. 3862 hsa-mir-21 Thyroid Neoplasms 21159845 Papillary Thyroid Carcinoma (PTC). Direct interaction with THRB was shown for miR-21 and miR-146a. 3863 hsa-mir-146a Thyroid Neoplasms 21159845 Papillary Thyroid Carcinoma (PTC). Direct interaction with THRB was shown for miR-21 and miR-146a. 3864 hsa-mir-203 Prostatic Neoplasms 21159887 miR-203 expression is specifically attenuated in bone metastatic prostate cancer suggesting a fundamental anti-metastatic role for this miRNA 3865 hsa-mir-569 Lupus Erythematosus, Systemic 21162035 Association of a functional polymorphism in the 3' untranslated region of SPI1 with systemic lupus erythematosus. 3866 hsa-mir-373 Cholangiocarcinoma 21165562 Methyl-CpG binding protein MBD2 is implicated in methylation-mediated suppression of miR-373 in hilar Cholangiocarcinoma. 3867 hsa-mir-126 Lupus Erythematosus, Systemic 21165896 MicroRNA-126 regulates DNA methylation in CD4(+) T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1. 3868 hsa-mir-125b-1 Nevus, Pigmented 21166724 The microRNA molecular signature of atypic and common acquired melanocytic nevi: differential expression of miR-125b and let-7c. 3869 hsa-mir-125b-2 Nevus, Pigmented 21166724 The microRNA molecular signature of atypic and common acquired melanocytic nevi: differential expression of miR-125b and let-7c. 3870 hsa-let-7c Nevus, Pigmented 21166724 The microRNA molecular signature of atypic and common acquired melanocytic nevi: differential expression of miR-125b and let-7c. 3871 hsa-mir-96 Urinary Bladder Neoplasms 21166959 MiR-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma: correlation with stage and grade, and comparison with urinary cytology. 3872 hsa-mir-183 Urinary Bladder Neoplasms 21166959 MiR-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma: correlation with stage and grade, and comparison with urinary cytology. 3873 hsa-mir-181a-1 Carcinoma, Squamous Cell 21167132 miR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras? 3874 hsa-mir-181a-2 Carcinoma, Squamous Cell 21167132 miR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras? 3875 hsa-mir-22 Panic Disorder 21168126 Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 Are Associated with Panic Disorder and Regulate Several Anxiety Candidate Genes and Related Pathways. 3876 hsa-mir-138-2 Panic Disorder 21168126 Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 Are Associated with Panic Disorder and Regulate Several Anxiety Candidate Genes and Related Pathways. 3877 hsa-mir-148a Panic Disorder 21168126 Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 Are Associated with Panic Disorder and Regulate Several Anxiety Candidate Genes and Related Pathways. 3878 hsa-mir-488 Panic Disorder 21168126 Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 Are Associated with Panic Disorder and Regulate Several Anxiety Candidate Genes and Related Pathways. 3879 hsa-mir-1-1 Myotonic Dystrophy 21169019 We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls. 3880 hsa-mir-335 Myotonic Dystrophy 21169019 We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls. 3881 hsa-mir-29b-1 Myotonic Dystrophy 21169019 We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls. 3882 hsa-mir-29b-2 Myotonic Dystrophy 21169019 We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls. 3883 hsa-mir-29c Myotonic Dystrophy 21169019 We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls. 3884 hsa-mir-33a Myotonic Dystrophy 21169019 We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls. 3885 hsa-mir-33b Myotonic Dystrophy 21169019 We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls. 3886 hsa-mir-516a-1 Stomach Neoplasms 21169410 The metastasis associated microRNA miR-516a-3p is a novel therapeutic target for inhibiting peritoneal dissemination of human scirrhous gastric cancer. 3887 hsa-mir-516a-2 Stomach Neoplasms 21169410 The metastasis associated microRNA miR-516a-3p is a novel therapeutic target for inhibiting peritoneal dissemination of human scirrhous gastric cancer. 3888 hsa-mir-21 AIDS Dementia Complex 21170291 MicroRNA-21 dysregulates the expression of MEF2C in neurons in monkey and human SIV/HIV neurological disease. 3889 hsa-mir-593 Esophageal Neoplasms 21170987 Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal cancer. 3890 hsa-mir-342 Breast Neoplasms 21172025 Downregulation of miR-342 is Associated with Tamoxifen Resistant Breast Tumors. 3891 hsa-mir-101-1 Alzheimer Disease 21172309 MicroRNA-101 downregulates Alzheimer's amyloid-beta precursor protein levels in human cell cultures and is differentially expressed. 3892 hsa-mir-371a Neoplasms 21173133 Identification of MicroRNAs From the miR-371~373 and miR-302 Clusters as Potential Serum Biomarkers of Malignant Germ Cell Tumors. 3893 hsa-mir-372 Neoplasms 21173133 Identification of MicroRNAs From the miR-371~373 and miR-302 Clusters as Potential Serum Biomarkers of Malignant Germ Cell Tumors. 3894 hsa-mir-373 Neoplasms 21173133 Identification of MicroRNAs From the miR-371~373 and miR-302 Clusters as Potential Serum Biomarkers of Malignant Germ Cell Tumors. 3895 hsa-mir-302a Neoplasms 21173133 Identification of MicroRNAs From the miR-371~373 and miR-302 Clusters as Potential Serum Biomarkers of Malignant Germ Cell Tumors. 3896 hsa-mir-302b Neoplasms 21173133 Identification of MicroRNAs From the miR-371~373 and miR-302 Clusters as Potential Serum Biomarkers of Malignant Germ Cell Tumors. 3897 hsa-mir-302c Neoplasms 21173133 Identification of MicroRNAs From the miR-371~373 and miR-302 Clusters as Potential Serum Biomarkers of Malignant Germ Cell Tumors. 3898 hsa-mir-302d Neoplasms 21173133 Identification of MicroRNAs From the miR-371~373 and miR-302 Clusters as Potential Serum Biomarkers of Malignant Germ Cell Tumors. 3899 hsa-mir-367 Neoplasms 21173133 Identification of MicroRNAs From the miR-371~373 and miR-302 Clusters as Potential Serum Biomarkers of Malignant Germ Cell Tumors. 3900 hsa-mir-150 Colorectal Neoplasms 21174058 miR-150*, miR-125b-2*, miR-1179 and miR-139-3p were up-regulated in colorectal cancers with liver metastasis 3901 hsa-mir-125b-2 Colorectal Neoplasms 21174058 miR-150*, miR-125b-2*, miR-1179 and miR-139-3p were up-regulated in colorectal cancers with liver metastasis 3902 hsa-mir-1179 Colorectal Neoplasms 21174058 miR-150*, miR-125b-2*, miR-1179 and miR-139-3p were up-regulated in colorectal cancers with liver metastasis 3903 hsa-mir-139 Colorectal Neoplasms 21174058 miR-150*, miR-125b-2*, miR-1179 and miR-139-3p were up-regulated in colorectal cancers with liver metastasis 3904 hsa-mir-24-1 Liver Neoplasms 21175813 upregulated after arsenic trioxide treatment in HepG-2 cells 3905 hsa-mir-24-2 Liver Neoplasms 21175813 upregulated after arsenic trioxide treatment in HepG-2 cells 3906 hsa-mir-29a Liver Neoplasms 21175813 upregulated after arsenic trioxide treatment in HepG-2 cells miR-29a showed a positive therapeutic effect in liver cancer cells by inhibiting cell growth and inducing cell apoptosis, and PPM1D was confirmed to be the target gene of miR-29a. 3907 hsa-mir-30a Liver Neoplasms 21175813 upregulated after arsenic trioxide treatment in HepG-2 cells 3908 hsa-mir-210 Liver Neoplasms 21175813 upregulated after arsenic trioxide treatment in HepG-2 cells 3909 hsa-mir-10b Liver Neoplasms 21176238 overexpressed in side population of HCC cells compared to fetal liver cells 3910 hsa-mir-21 Liver Neoplasms 21176238 overexpressed in side population of HCC cells compared to fetal liver cells 3911 hsa-mir-34c Liver Neoplasms 21176238 miR-34c-3p is overexpressed in side population of HCC cells compared to fetal liver cells 3912 hsa-let-7i Liver Neoplasms 21176238 let-7i* is overexpressed in side population of HCC cells compared to fetal liver cells 3913 hsa-mir-200a Liver Neoplasms 21176238 mir-200a* is underexpressed in side population of HCC cells compared to fetal liver cells 3914 hsa-mir-148b Liver Neoplasms 21176238 mir-148b* is underexpressed in side population of HCC cells compared to fetal liver cells 3915 hsa-mir-155 Endometrial Neoplasms 21176560 Hsa-miR-155 may play an important role in the proliferation, and metastasis of endometrial cancer, which may be a indicator in the diagnosis and prognosis of endometrial cancer and may be used as a predictive biomarker. 3916 hsa-mir-183 Ovarian Neoplasms 21176563 Increased expression of miR-183 and miR-22 may both repress the protein level of ezrin, indicating that miR-183 and miR-22 may bear a potential role in inhibiting ovarian cancer metastasis in a ezrin-mediated way 3917 hsa-mir-22 Ovarian Neoplasms 21176563 Increased expression of miR-183 and miR-22 may both repress the protein level of ezrin, indicating that miR-183 and miR-22 may bear a potential role in inhibiting ovarian cancer metastasis in a ezrin-mediated way 3918 hsa-mir-21 Prostatic Neoplasms 21177307 We also observed a significant down-regulation of androgen-regulated miRNA-21 and up-regulation of a tumor suppressor, miRNA-330, in tumors of mice treated with EGCG 3919 hsa-mir-330 Prostatic Neoplasms 21177307 We also observed a significant down-regulation of androgen-regulated miRNA-21 and up-regulation of a tumor suppressor, miRNA-330, in tumors of mice treated with EGCG 3920 hsa-mir-30a Medulloblastoma 21177782 miR-34a confers chemosensitivity through modulation of MAGE-A and p53 in medulloblastoma. 3921 hsa-mir-30a Glioblastoma 21178384 the transcriptional BDNF inhibitor miR-30a-5p was also overexpressed at 6 and 12 h of paroxetine incubation 3922 hsa-mir-424 Hemangioma 21179471 Down-Regulation of mir-424 Contributes to the Abnormal Angiogenesis via MEK1 and Cyclin E1 in Senile Hemangioma: Its Implications to Therapy. 3923 hsa-mir-103a-1 Alzheimer Disease 21179570 microRNAs 103 and 107 repress translation of cofilin, and that reduced levels of miR-103 or miR-107 are associated with elevated cofilin protein levels and formation of rod-like structures in a transgenic mouse model of AD 3924 hsa-mir-103a-2 Alzheimer Disease 21179570 microRNAs 103 and 107 repress translation of cofilin, and that reduced levels of miR-103 or miR-107 are associated with elevated cofilin protein levels and formation of rod-like structures in a transgenic mouse model of AD 3925 hsa-mir-107 Alzheimer Disease 21179570 microRNAs 103 and 107 repress translation of cofilin, and that reduced levels of miR-103 or miR-107 are associated with elevated cofilin protein levels and formation of rod-like structures in a transgenic mouse model of AD 3926 hsa-mir-92a-1 Leukemia 21182798 The miR-92a expression in leukemia cells could be a prognostic factor in ALL patients 3927 hsa-mir-92a-2 Leukemia 21182798 The miR-92a expression in leukemia cells could be a prognostic factor in ALL patients 3928 hsa-mir-98 Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. 3929 hsa-let-7a-1 Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. 3930 hsa-let-7a-2 Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. 3931 hsa-let-7a-3 Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. 3932 hsa-let-7b Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. 3933 hsa-let-7c Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. 3934 hsa-let-7d Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. 3935 hsa-let-7e Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. 3936 hsa-let-7f-1 Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. 3937 hsa-let-7f-2 Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. 3938 hsa-let-7g Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. 3939 hsa-let-7i Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. 3940 hsa-mir-185 Colorectal Neoplasms 21186079 miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells.miR-185 is a negative regulator of RhoA and Cdc42 and their cellular activities, and could inhibit proliferation and invasion of colorectal cancer cells 3941 hsa-mir-21 Leukemia 21187093 Involvement of miR-21 in resistance to daunorubicin by regulating PTEN expression in the leukaemia K562 cell line. 3942 hsa-mir-199a-1 Neoplasms 21189327 microRNAs miR-199a-5p and -3p target the Brm subunit of SWI/SNF to generate a double-negative feedback loop in a variety of human cancers. 3943 hsa-mir-199a-2 Neoplasms 21189327 microRNAs miR-199a-5p and -3p target the Brm subunit of SWI/SNF to generate a double-negative feedback loop in a variety of human cancers. 3944 hsa-mir-16-1 Carcinoma, Non-Small-Cell Lung 21192009 Prognostic implications of miR-16 expression levels in resected non-small-cell lung cancer. 3945 hsa-mir-16-2 Carcinoma, Non-Small-Cell Lung 21192009 Prognostic implications of miR-16 expression levels in resected non-small-cell lung cancer. 3946 hsa-mir-16-1 Carcinoma, Non-Small-Cell Lung 21192009 Prognostic implications of miR-16 expression levels in resected non-small-cell lung cancer 3947 hsa-mir-16-2 Carcinoma, Non-Small-Cell Lung 21192009 Prognostic implications of miR-16 expression levels in resected non-small-cell lung cancer 3948 hsa-mir-126 Coronary Artery Disease 21195052 Coronary Artery Disease 3949 hsa-mir-130a Coronary Artery Disease 21195052 Coronary Artery Disease 3950 hsa-mir-221 Coronary Artery Disease 21195052 Coronary Artery Disease 3951 hsa-mir-222 Coronary Artery Disease 21195052 Coronary Artery Disease 3952 hsa-mir-92a-1 Coronary Artery Disease 21195052 Coronary Artery Disease 3953 hsa-mir-92a-2 Coronary Artery Disease 21195052 Coronary Artery Disease 3954 hsa-mir-124-2 Glioblastoma 21196113 miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion. 3955 hsa-mir-143 Prostatic Neoplasms 21197560 miR-143 decreases prostate cancer cells proliferation and migration and enhances their sensitivity to docetaxel through suppression of KRAS 3956 hsa-mir-26a-1 Nasopharyngeal Neoplasms 21199804 MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2 3957 hsa-mir-26a-2 Nasopharyngeal Neoplasms 21199804 MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2 3958 hsa-mir-21 Lymphoma, B-Cell 21200023 diffuse large B-cell lymphoma 3959 hsa-mir-19a Lymphoma, B-Cell 21200023 diffuse large B-cell lymphoma 3960 hsa-mir-19b-1 Lymphoma, B-Cell 21200023 diffuse large B-cell lymphoma 3961 hsa-mir-19b-2 Lymphoma, B-Cell 21200023 diffuse large B-cell lymphoma 3962 hsa-mir-92a-1 Lymphoma, B-Cell 21200023 diffuse large B-cell lymphoma 3963 hsa-mir-92a-2 Lymphoma, B-Cell 21200023 diffuse large B-cell lymphoma 3964 hsa-mir-96 Breast Neoplasms 21203424 Unregulated miR-96 Induces Cell Proliferation in Human Breast Cancer by Downregulating Transcriptional Factor FOXO3a. 3965 hsa-mir-17 Prostatic Neoplasms 21203553 miR-17* Suppresses Tumorigenicity of Prostate Cancer by Inhibiting Mitochondrial Antioxidant Enzymes. 3966 hsa-mir-203 Urinary Bladder Neoplasms 21205209 microRNA-203 suppresses bladder cancer development by repressing bcl-w expression. 3967 hsa-mir-148b Stomach Neoplasms 21205300 MicroRNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferation. 3968 hsa-mir-15a Patau Syndrome 21205891 MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13. 3969 hsa-mir-16-1 Patau Syndrome 21205891 MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13. 3970 hsa-mir-16-2 Patau Syndrome 21205891 MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13. 3971 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 3972 hsa-mir-15b Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 3973 hsa-mir-16-1 Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 3974 hsa-mir-16-2 Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 3975 hsa-mir-195 Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 3976 hsa-mir-34b Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 3977 hsa-mir-34c Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 3978 hsa-mir-143 Glioblastoma 21211035 down regulation of miR-143, -145, -253-5p and miR-452 by SOX2 3979 hsa-mir-145 Glioblastoma 21211035 down regulation of miR-143, -145, -253-5p and miR-452 by SOX2 3980 hsa-mir-452 Glioblastoma 21211035 down regulation of miR-143, -145, -253-5p and miR-452 by SOX2 3981 hsa-mir-378a Myelodysplastic Syndromes 21211043 miR-378 and miR-146a showed reduced gene expression in the patients. 3982 hsa-mir-146a Myelodysplastic Syndromes 21211043 miR-378 and miR-146a showed reduced gene expression in the patients. 3983 hsa-mir-99a Prostatic Neoplasms 21212412 miR-99 family of microRNAs suppresses the expression of prostate specific antigen and prostate cancer cell proliferation. 3984 hsa-mir-99b Prostatic Neoplasms 21212412 miR-99 family of microRNAs suppresses the expression of prostate specific antigen and prostate cancer cell proliferation. 3985 hsa-mir-100 Prostatic Neoplasms 21212412 miR-99 family of microRNAs suppresses the expression of prostate specific antigen and prostate cancer cell proliferation. 3986 hsa-mir-10a Neuroblastoma 21212796 MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2. 3987 hsa-mir-10b Neuroblastoma 21212796 MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2. 3988 hsa-mir-31 Muscular Dystrophy, Duchenne 21212803 miR-31 represses dystrophin expression by targeting its 3' untranslated region. 3989 hsa-mir-34b Stomach Neoplasms 21213213 upstream CpG-rich regions of mir-34b and mir-129-2 are frequently methylated in gastric cancer tissues compared with adjacent normal tissues, and their methylation status correlated inversely with their expression patterns. 3990 hsa-mir-129-2 Stomach Neoplasms 21213213 upstream CpG-rich regions of mir-34b and mir-129-2 are frequently methylated in gastric cancer tissues compared with adjacent normal tissues, and their methylation status correlated inversely with their expression patterns. 3991 hsa-mir-153-1 Glioblastoma 21213215 Chromatin-modifying drugs induce miRNA-153 expression to suppress Irs-2 in glioblastoma cell lines 3992 hsa-let-7e Sarcoma, Synovial 21213367 upregulated 3993 hsa-mir-99b Sarcoma, Synovial 21213367 upregulated 3994 hsa-mir-125a Sarcoma, Synovial 21213367 hsa-miR-125a-3p upregulated 3995 hsa-mir-214 Uterine Cervical Neoplasms 21216304 Plexin-B1 is a target of miR-214 in cervical cancer and promotes the growth and invasion of HeLa Cells. 3996 hsa-mir-145 Sarcoma, Ewing's 21217773 Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcoma. 3997 hsa-mir-143 Esophageal Neoplasms 21218087 MiRNA profile in esophageal squamous cell carcinoma: Downregulation of miR-143 and miR-145. 3998 hsa-mir-145 Esophageal Neoplasms 21218087 MiRNA profile in esophageal squamous cell carcinoma: Downregulation of miR-143 and miR-145. 3999 hsa-mir-21 Breast Neoplasms 21219636 Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth 4000 hsa-mir-155 Carcinoma, Non-Small-Cell Lung 21219656 The prognostic impact of miR-155 depends on histological subtype and nodal status in NSCLC. 4001 hsa-mir-328 Breast Neoplasms 21219875 Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328; -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells. 4002 hsa-mir-519c Breast Neoplasms 21219875 Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328; -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells. 4003 hsa-mir-520h Breast Neoplasms 21219875 Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328; -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells. 4004 hsa-mir-125a Stomach Neoplasms 21220473 MicroRNA-125a-5p is an independent prognostic factor in gastric cancer,and inhibits the proliferation of human gastric cancer cells in combination with trastuzumab. 4005 hsa-mir-503 Diabetes Mellitus 21220732 Deregulation of microRNA-503 Contributes to Diabetes Mellitus-Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia. 4006 hsa-mir-137 Stomach Neoplasms 21221794 miR-137 Is Frequently Down-Regulated in Gastric Cancer and Is a Negative Regulator of Cdc42. 4007 hsa-mir-29b-1 Urinary Bladder Neoplasms 21223810 In grade I, grade II, grade III, grade I + II + III, infiltrating and non-infiltrating groups, hsa-miR-29b-1* was up-regulated while hsa-miR-923 and hsa-miR-300 were down-regulated 4008 hsa-mir-300 Urinary Bladder Neoplasms 21223810 In grade I, grade II, grade III, grade I + II + III, infiltrating and non-infiltrating groups, hsa-miR-29b-1* was up-regulated while hsa-miR-923 and hsa-miR-300 were down-regulated 4009 hsa-mir-28 HIV Infections 21224041 heroin-dependent subjects had significantly lower levels of anti-HIV miRNAs (miRNA-28, 125b, 150, and 382) in peripheral blood mononuclear cells than the healthy subjects 4010 hsa-mir-150 HIV Infections 21224041 heroin-dependent subjects had significantly lower levels of anti-HIV miRNAs (miRNA-28, 125b, 150, and 382) in peripheral blood mononuclear cells than the healthy subjects 4011 hsa-mir-382 HIV Infections 21224041 heroin-dependent subjects had significantly lower levels of anti-HIV miRNAs (miRNA-28, 125b, 150, and 382) in peripheral blood mononuclear cells than the healthy subjects 4012 hsa-mir-125b-1 HIV Infections 21224041 heroin-dependent subjects had significantly lower levels of anti-HIV miRNAs (miRNA-28, 125b, 150, and 382) in peripheral blood mononuclear cells than the healthy subjects 4013 hsa-mir-125b-2 HIV Infections 21224041 heroin-dependent subjects had significantly lower levels of anti-HIV miRNAs (miRNA-28, 125b, 150, and 382) in peripheral blood mononuclear cells than the healthy subjects 4014 hsa-mir-616 Prostatic Neoplasms 21224345 microRNA-616 Induces Androgen-Independent Growth of Prostate Cancer Cells by Suppressing Expression of Tissue Factor Pathway Inhibitor TFPI-2. 4015 hsa-mir-376c Ovarian Neoplasms 21224400 MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance. 4016 hsa-mir-200a Prostatic Neoplasms 21224847 Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells. 4017 hsa-mir-200b Prostatic Neoplasms 21224847 Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells. 4018 hsa-mir-200c Prostatic Neoplasms 21224847 Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells. 4019 hsa-mir-200a Pancreatic Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. 4020 hsa-mir-200b Pancreatic Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. 4021 hsa-mir-200c Pancreatic Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. 4022 hsa-mir-200a Breast Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. 4023 hsa-mir-200b Breast Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. 4024 hsa-mir-200c Breast Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. 4025 hsa-mir-34a Colorectal Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4026 hsa-mir-34a Pancreatic Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4027 hsa-mir-34a Breast Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4028 hsa-mir-34a Urinary Bladder Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4029 hsa-mir-34a Carcinoma, Renal Cell 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4030 hsa-mir-34b Colorectal Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4031 hsa-mir-34b Pancreatic Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4032 hsa-mir-34b Breast Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4033 hsa-mir-34b Urinary Bladder Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4034 hsa-mir-34b Carcinoma, Renal Cell 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4035 hsa-mir-34c Colorectal Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4036 hsa-mir-34c Pancreatic Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4037 hsa-mir-34c Breast Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4038 hsa-mir-34c Urinary Bladder Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4039 hsa-mir-34c Carcinoma, Renal Cell 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4040 hsa-mir-34a Ovarian Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4041 hsa-mir-34a Sarcoma 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4042 hsa-mir-34b Ovarian Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4043 hsa-mir-34b Sarcoma 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4044 hsa-mir-34c Ovarian Neoplasms 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4045 hsa-mir-34c Sarcoma 21225432 Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas. 4046 hsa-mir-9-1 Stomach Neoplasms 21225631 MiR-9 down-regulates CDX2 expression in gastric cancer cells. 4047 hsa-mir-9-2 Stomach Neoplasms 21225631 MiR-9 down-regulates CDX2 expression in gastric cancer cells. 4048 hsa-mir-9-3 Stomach Neoplasms 21225631 MiR-9 down-regulates CDX2 expression in gastric cancer cells. 4049 hsa-mir-9-1 Stomach Neoplasms 21225631 MiR-9 downregulates CDX2 expression in gastric cancer cells. 4050 hsa-mir-9-2 Stomach Neoplasms 21225631 MiR-9 downregulates CDX2 expression in gastric cancer cells. 4051 hsa-mir-9-3 Stomach Neoplasms 21225631 MiR-9 downregulates CDX2 expression in gastric cancer cells. 4052 hsa-mir-340 Breast Neoplasms 21225860 miR-340 inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c-Met 4053 hsa-mir-221 Neoplasms, Squamous Cell 21226887 miR-221 and miR-222 expression increased the growth and tumorigenesis of oral carcinoma cells. 4054 hsa-mir-222 Neoplasms, Squamous Cell 21226887 miR-221 and miR-222 expression increased the growth and tumorigenesis of oral carcinoma cells. 4055 hsa-let-7a-1 Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4056 hsa-let-7a-2 Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4057 hsa-let-7a-3 Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4058 hsa-let-7b Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4059 hsa-let-7c Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4060 hsa-let-7d Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4061 hsa-let-7e Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4062 hsa-let-7f-1 Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4063 hsa-let-7f-2 Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4064 hsa-let-7g Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4065 hsa-let-7i Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4066 hsa-mir-30c-1 Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4067 hsa-mir-30c-2 Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4068 hsa-mir-26a-1 Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4069 hsa-mir-26a-2 Carcinoma, Renal Cell 21229250 let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours. 4070 hsa-mir-21 Carcinoma, Hepatocellular 21229610 Our results indicate that serum miR-21, miR-122 and miR-223 are elevated in patients with HCC or chronic hepatitis and these miRNAs have strong potential to serve as novel biomarkers for liver injury but not specifically for HCC. 4071 hsa-mir-122 Carcinoma, Hepatocellular 21229610 Our results indicate that serum miR-21, miR-122 and miR-223 are elevated in patients with HCC or chronic hepatitis and these miRNAs have strong potential to serve as novel biomarkers for liver injury but not specifically for HCC. 4072 hsa-mir-223 Carcinoma, Hepatocellular 21229610 Our results indicate that serum miR-21, miR-122 and miR-223 are elevated in patients with HCC or chronic hepatitis and these miRNAs have strong potential to serve as novel biomarkers for liver injury but not specifically for HCC. 4073 hsa-mir-885 Neuroblastoma 21233845 MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival. 4074 hsa-mir-155 Pre-Eclampsia 21234519 microRNA-155 regulates angiotensin II type 1 receptor expression in umbilical vein endothelial cells from severely pre-eclamptic pregnant women. 4075 hsa-mir-200a Carcinoma 21237487 Down-regulation of microRNAs of the miR-200 family and miR-205, and an altered expression of classic and desmosomal cadherins in spindle cell carcinoma of the head and neck-hallmark of epithelial-mesenchymal transition. 4076 hsa-mir-200b Carcinoma 21237487 Down-regulation of microRNAs of the miR-200 family and miR-205, and an altered expression of classic and desmosomal cadherins in spindle cell carcinoma of the head and neck-hallmark of epithelial-mesenchymal transition. 4077 hsa-mir-200c Carcinoma 21237487 Down-regulation of microRNAs of the miR-200 family and miR-205, and an altered expression of classic and desmosomal cadherins in spindle cell carcinoma of the head and neck-hallmark of epithelial-mesenchymal transition. 4078 hsa-mir-205 Carcinoma 21237487 Down-regulation of microRNAs of the miR-200 family and miR-205, and an altered expression of classic and desmosomal cadherins in spindle cell carcinoma of the head and neck-hallmark of epithelial-mesenchymal transition. 4079 hsa-mir-34a Prostatic Neoplasms 21240262 The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. 4080 hsa-mir-196a-2 Colorectal Neoplasms 21241442 A variant ( rs11614913 ) in microRNA-196a2 is not associated with susceptibility to and progression of colorectal cancer in Chinese. 4081 hsa-let-7b Precursor Cell Lymphoblastic Leukemia-Lymphoma 21242186 aberrant downregulation of let-7b (~70-fold) in MLL-rearranged acute lymphoblastic leukemia was linked to upregulation of oncoprotein c-Myc (P<0.0001). Resistance to vincristine and daunorubicin was characterized by ~20-fold upregulation of miR-125b, miR-99a and miR-100 (P≿.002). 4082 hsa-mir-125b-1 Precursor Cell Lymphoblastic Leukemia-Lymphoma 21242186 aberrant downregulation of let-7b (~70-fold) in MLL-rearranged acute lymphoblastic leukemia was linked to upregulation of oncoprotein c-Myc (P<0.0001). Resistance to vincristine and daunorubicin was characterized by ~20-fold upregulation of miR-125b, miR-99a and miR-100 (P≿.002). 4083 hsa-mir-125b-2 Precursor Cell Lymphoblastic Leukemia-Lymphoma 21242186 aberrant downregulation of let-7b (~70-fold) in MLL-rearranged acute lymphoblastic leukemia was linked to upregulation of oncoprotein c-Myc (P<0.0001). Resistance to vincristine and daunorubicin was characterized by ~20-fold upregulation of miR-125b, miR-99a and miR-100 (P≿.002). 4084 hsa-mir-100 Precursor Cell Lymphoblastic Leukemia-Lymphoma 21242186 aberrant downregulation of let-7b (~70-fold) in MLL-rearranged acute lymphoblastic leukemia was linked to upregulation of oncoprotein c-Myc (P<0.0001). Resistance to vincristine and daunorubicin was characterized by ~20-fold upregulation of miR-125b, miR-99a and miR-100 (P≿.002). 4085 hsa-mir-99a Precursor Cell Lymphoblastic Leukemia-Lymphoma 21242186 aberrant downregulation of let-7b (~70-fold) in MLL-rearranged acute lymphoblastic leukemia was linked to upregulation of oncoprotein c-Myc (P<0.0001). Resistance to vincristine and daunorubicin was characterized by ~20-fold upregulation of miR-125b, miR-99a and miR-100 (P≿.002). 4086 hsa-mir-20a Colorectal Neoplasms 21242194 miR-20a targets BNIP2 and contributes chemotherapeutic resistance in colorectal adenocarcinoma SW480 and SW620 cell lines. 4087 hsa-mir-378a Neoplasms 21242960 Myc/miR-378/TOB2/cyclin D1 functional module regulates oncogenic transformation. 4088 hsa-mir-23b Uterine Cervical Neoplasms 21242962 Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53/microRNA-23b/urokinase-type plasminogen activator pathway. 4089 hsa-mir-181a-1 Neoplasms, Squamous Cell 21244495 miR-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma.miR-181 may enhance lymph-node metastasis through regulating migration, which could potentially be exploited as a putative biomarker for patients with OSCC. 4090 hsa-mir-181a-2 Neoplasms, Squamous Cell 21244495 miR-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma.miR-181 may enhance lymph-node metastasis through regulating migration, which could potentially be exploited as a putative biomarker for patients with OSCC. 4091 hsa-mir-181b-1 Neoplasms, Squamous Cell 21244495 miR-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma.miR-181 may enhance lymph-node metastasis through regulating migration, which could potentially be exploited as a putative biomarker for patients with OSCC. 4092 hsa-mir-181b-2 Neoplasms, Squamous Cell 21244495 miR-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma.miR-181 may enhance lymph-node metastasis through regulating migration, which could potentially be exploited as a putative biomarker for patients with OSCC. 4093 hsa-mir-181c Neoplasms, Squamous Cell 21244495 miR-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma.miR-181 may enhance lymph-node metastasis through regulating migration, which could potentially be exploited as a putative biomarker for patients with OSCC. 4094 hsa-mir-181d Neoplasms, Squamous Cell 21244495 miR-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma.miR-181 may enhance lymph-node metastasis through regulating migration, which could potentially be exploited as a putative biomarker for patients with OSCC. 4095 hsa-mir-489 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4096 hsa-mir-129-1 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4097 hsa-mir-129-2 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4098 hsa-mir-23a Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4099 hsa-mir-214 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4100 hsa-mir-23b Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4101 hsa-mir-92a-1 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4102 hsa-mir-92a-2 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4103 hsa-mir-92b Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4104 hsa-mir-25 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4105 hsa-mir-210 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4106 hsa-mir-212 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4107 hsa-mir-515-1 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4108 hsa-mir-515-2 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4109 hsa-mir-146b Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4110 hsa-mir-21 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4111 hsa-mir-338 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4112 hsa-mir-520h Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4113 hsa-mir-197 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4114 hsa-mir-378a Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4115 hsa-mir-135b Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4116 hsa-mir-224 Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4117 hsa-mir-34a Neoplasms, Squamous Cell 21244772 Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours. 4118 hsa-mir-221 Glioblastoma 21245048 NF-kB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells. 4119 hsa-mir-221 Prostatic Neoplasms 21245048 NF-kB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells. 4120 hsa-mir-148a Esophageal Neoplasms 21246413 Mir-148a Improves Response to Chemotherapy in Sensitive and Resistant Oesophageal Adenocarcinoma and Squamous Cell Carcinoma Cells. 4121 hsa-mir-148a Carcinoma, Squamous Cell 21246413 Mir-148a Improves Response to Chemotherapy in Sensitive and Resistant Oesophageal Adenocarcinoma and Squamous Cell Carcinoma Cells. 4122 hsa-mir-200c Esophageal Neoplasms 21248297 Overexpression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway. 4123 hsa-mir-146a Diabetes Mellitus, Type 2 21249428 Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes. 4124 hsa-mir-126 Breast Neoplasms 21249429 Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2. 4125 hsa-mir-485 Leukemia 21252292 Novel regulation of NF-YB by miR-485-3p affects expression of DNA topoisomerase II{alpha} and drug responsiveness in human lymphoblastic leukemia CEM cells. 4126 hsa-mir-210 Carcinoma, Renal Cell 21253009 miR-210, miR-184 and miR-206) play pivotal roles in ccRCC development 4127 hsa-mir-184 Carcinoma, Renal Cell 21253009 miR-210, miR-184 and miR-206) play pivotal roles in ccRCC development 4128 hsa-mir-206 Carcinoma, Renal Cell 21253009 miR-210, miR-184 and miR-206) play pivotal roles in ccRCC development 4129 hsa-mir-205 Prostatic Neoplasms 21255435 We find miR-205, miR-21, and miR-196b to be epigenetically repressed, and miR-615 epigenetically activated in prostate cancer cells. 4130 hsa-mir-21 Prostatic Neoplasms 21255435 We find miR-205, miR-21, and miR-196b to be epigenetically repressed, and miR-615 epigenetically activated in prostate cancer cells. 4131 hsa-mir-196b Prostatic Neoplasms 21255435 We find miR-205, miR-21, and miR-196b to be epigenetically repressed, and miR-615 epigenetically activated in prostate cancer cells. 4132 hsa-mir-1254-1 Carcinoma, Non-Small-Cell Lung 21258252 miR-1254 and miR-574-5p: Serum-Based microRNA Biomarkers for Early-Stage Non-small Cell Lung Cancer. The expression of hsa-miR-1254 and hsa-miR-574-5p was significantly increased in the early-stage NSCLC samples with respect to the controls. The utility of miR-1254 and miR-574-5p serum-based biomarkers as minimally invasive screening and triage tools for subsequent diagnostic evaluation warrants additional validation. 4133 hsa-mir-574 Carcinoma, Non-Small-Cell Lung 21258252 miR-1254 and miR-574-5p: Serum-Based microRNA Biomarkers for Early-Stage Non-small Cell Lung Cancer. The expression of hsa-miR-1254 and hsa-miR-574-5p was significantly increased in the early-stage NSCLC samples with respect to the controls. The utility of miR-1254 and miR-574-5p serum-based biomarkers as minimally invasive screening and triage tools for subsequent diagnostic evaluation warrants additional validation. 4134 hsa-mir-495 Breast Neoplasms 21258409 miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1. 4135 hsa-mir-145 Prostatic Neoplasms 21258769 Restoration of miR-145 expression suppresses cell proliferation, migration and invasion in prostate cancer by targeting FSCN1. 4136 hsa-mir-497 Gastrointestinal Neoplasms 21258880 miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2. 4137 hsa-mir-497 Lung Neoplasms 21258880 miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2. 4138 hsa-mir-146a Periodontal Diseases 21263019 Polymicrobial Infection with Periodontal Pathogens Specifically enhances miR-146a in ApoE-/- Mice during Experimental Periodontal Disease. 4139 hsa-mir-26b Glioma 21264258 This study demonstrated that miR-26b may act as a tumor suppressor in glioma and it directly regulates EphA2 expression. EphA2 is a direct target of miR-26b, and the down-regulation of EphA2 mediated by miR-26b is dependent on the binding of miR-26b to a specific response element of microRNA in the 3'UTR region of EphA2 mRNA. 4140 hsa-mir-107 Gastrointestinal Neoplasms 21264532 miR-107 targets cyclin-dependent kinase 6 expression, induces cell cycle G1 arrest and inhibits invasion in gastric cancer cells. 4141 hsa-mir-126 Carcinoma, Non-Small-Cell Lung 21264844 Independent and tissue-specific prognostic impact of miR-126 in nonsmall cell lung cancer: Coexpression with vascular endothelial growth factor-A predicts poor survival. 4142 hsa-mir-34a Neuroblastoma 21266077 This microRNA is a potent tumor suppressor molecule in vivo in neuroblastoma. 4143 hsa-mir-1258 Breast Neoplasms 21266359 Suppresses Breast Cancer Brain Metastasis by Targeting Heparanase. 4144 hsa-mir-146b Glioblastoma 21266476 Induction of miR-146b by PDGF-BB is modulated via MAPK-dependent induction of c-fos. 4145 hsa-mir-146b Ovarian Neoplasms 21266476 Induction of miR-146b by PDGF-BB is modulated via MAPK-dependent induction of c-fos. 4146 hsa-mir-29b-1 Atherosclerosis 21266537 OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases. 4147 hsa-mir-29b-2 Atherosclerosis 21266537 OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases. 4148 hsa-mir-126 Esophageal Neoplasms 21269950 hsa-miR-126 is upregulated and hsa-miR-518b is downregulated in esophageal squamous carcinoma 4149 hsa-mir-518b Esophageal Neoplasms 21269950 hsa-miR-126 is upregulated and hsa-miR-518b is downregulated in esophageal squamous carcinoma 4150 hsa-mir-21 Breast Neoplasms 21270527 miR-21, miR-210 and miR-221 were significantly overexpressed, whereas miR-10b, miR-145, miR-205, miR-122a were significantly underexpressed in the triple-negative primary breast cancers. 4151 hsa-mir-210 Breast Neoplasms 21270527 miR-21, miR-210 and miR-221 were significantly overexpressed, whereas miR-10b, miR-145, miR-205, miR-122a were significantly underexpressed in the triple-negative primary breast cancers. 4152 hsa-mir-221 Breast Neoplasms 21270527 miR-21, miR-210 and miR-221 were significantly overexpressed, whereas miR-10b, miR-145, miR-205, miR-122a were significantly underexpressed in the triple-negative primary breast cancers. 4153 hsa-mir-101-1 Carcinoma, Non-Small-Cell Lung 21270667 MicroRNA-101 Exerts Tumor-Suppressive Functions in Non-small Cell Lung Cancer through Directly Targeting Enhancer of Zeste Homolog 2. 4154 hsa-mir-101-2 Carcinoma, Non-Small-Cell Lung 21270667 MicroRNA-101 Exerts Tumor-Suppressive Functions in Non-small Cell Lung Cancer through Directly Targeting Enhancer of Zeste Homolog 2. 4155 hsa-mir-19a Esophageal Neoplasms 21271217 TNF-alpha is a novel target of miR-19a. 4156 hsa-mir-21 Breast Neoplasms 21271219 Increased miR-21 and miR-181a levels were significantly associated with shortened disease-free survival(DFS; p=0.0003, 0.0007) and overall survival (OS; p=0.0351, 0.0443), respectively. Accumulation of miR-21 and miR-181a in bone marrow appears to be associated with prognosis in breast cancer patients. The much higher significant correlation with microRNA levels and prognosis suggests epistatic effects on multiple target genes in the bone marrow of breast cancer patients. 4157 hsa-mir-181a-1 Breast Neoplasms 21271219 Increased miR-21 and miR-181a levels were significantly associated with shortened 4158 hsa-mir-181a-2 Breast Neoplasms 21271219 Increased miR-21 and miR-181a levels were significantly associated with shortened 4159 hsa-mir-373 Breast Neoplasms 21271679 miR-373 was found to be capable of promoting breast cancer invasion and metastasis 4160 hsa-mir-221 Melanoma 21273047 Malignant melanoma patients had significantly higher miR-221 levels than healthy controls in serum. 4161 hsa-mir-539 Mastocytosis, Systemic 21273305 We found that miR-539 and miR-381 are downregulated by KIT signaling and they repressed MITF expression through conserved miRNA binding sites in the MITF 3' UTR. 4162 hsa-mir-381 Mastocytosis, Systemic 21273305 We found that miR-539 and miR-381 are downregulated by KIT signaling and they repressed MITF expression through conserved miRNA binding sites in the MITF 3' UTR. 4163 hsa-mir-181a-1 Carcinoma, Squamous Cell 21274007 deltaNp63alpha-dependent miRNA miR-181a, miR-519a, and miR-374a downregulation in HNSCC,miR-630 upregulation in HNSCC 4164 hsa-mir-181a-2 Carcinoma, Squamous Cell 21274007 deltaNp63alpha-dependent miRNA miR-181a, miR-519a, and miR-374a downregulation in HNSCC,miR-630 upregulation in HNSCC 4165 hsa-mir-519a-1 Carcinoma, Squamous Cell 21274007 deltaNp63alpha-dependent miRNA miR-181a, miR-519a, and miR-374a downregulation in HNSCC,miR-630 upregulation in HNSCC 4166 hsa-mir-519a-2 Carcinoma, Squamous Cell 21274007 deltaNp63alpha-dependent miRNA miR-181a, miR-519a, and miR-374a downregulation in HNSCC,miR-630 upregulation in HNSCC 4167 hsa-mir-21 Prostatic Neoplasms 21274675 the miRNA levels in patient blood were higher than that of the controls 4168 hsa-mir-141 Prostatic Neoplasms 21274675 the miRNA levels in patient blood were higher than that of the controls 4169 hsa-mir-221 Prostatic Neoplasms 21274675 the miRNA levels in patient blood were higher than that of the controls 4170 hsa-mir-96 Helplessness, Learned 21275079 mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain. 4171 hsa-mir-141 Helplessness, Learned 21275079 mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain. 4172 hsa-mir-182 Helplessness, Learned 21275079 mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain. 4173 hsa-mir-183 Helplessness, Learned 21275079 mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain. 4174 hsa-mir-200a Helplessness, Learned 21275079 mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain. 4175 hsa-mir-200b Helplessness, Learned 21275079 mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain. 4176 hsa-mir-200c Helplessness, Learned 21275079 mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain. 4177 hsa-mir-429 Helplessness, Learned 21275079 mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain. 4178 hsa-mir-221 Thyroid Neoplasms 21275764 mir-221 was overexpressed in 19 patients (p<0.0001) with a sensitive yield of 95%. 4179 hsa-mir-29a Inflammation 21276447 microRNA-29a could regulate pro-inflammatory cytokine secretion and scavenger receptor expression by targeting lipoprotein lipase in oxLDL-stimulated dendritic cells. 4180 hsa-mir-143 Colonic Neoplasms 21276449 The ecotropic viral integration site 1 oncoprotein (Evi1) is a transcriptional suppressor of the miRNA-143 gene. 4181 hsa-mir-429 Ovarian Neoplasms 21277012 Overexpression of miR-429 induces mesenchymal-to-epithelial transition (MET) in metastatic ovarian cancer cells. 4182 hsa-mir-16-1 Carcinoma, Hepatocellular 21278583 Serum levels of miR-16 and miR-199a were significantly lower in HCC than in CLD patients or control subjects (P<0.01). 4183 hsa-mir-16-2 Carcinoma, Hepatocellular 21278583 Serum levels of miR-16 and miR-199a were significantly lower in HCC than in CLD patients or control subjects (P<0.01). 4184 hsa-mir-199a-1 Carcinoma, Hepatocellular 21278583 Serum levels of miR-16 and miR-199a were significantly lower in HCC than in CLD patients or control subjects (P<0.01). 4185 hsa-mir-199a-2 Carcinoma, Hepatocellular 21278583 Serum levels of miR-16 and miR-199a were significantly lower in HCC than in CLD patients or control subjects (P<0.01). 4186 hsa-mir-196a-1 Crohn Disease 21278745 The common exonic synonymous SNP (c.313C>T) in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. 4187 hsa-mir-196a-2 Crohn Disease 21278745 The common exonic synonymous SNP (c.313C>T) in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. 4188 hsa-mir-196b Crohn Disease 21278745 The common exonic synonymous SNP (c.313C>T) in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. 4189 hsa-mir-221 Colorectal Neoplasms 21278784 MicroRNA-221 inhibits CDKN1C/p57 expression in human colorectal carcinoma. 4190 hsa-mir-21 Glioma 21278789 Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas. 4191 hsa-mir-137 Melanoma 21278922 MicroRNA-137 Targets Carboxyl-terminal Binding Protein 1 in Melanoma Cell Lines. 4192 hsa-mir-21 Colonic Neoplasms 21279518 PDCD4 nuclear loss inversely correlates with miR-21 levels in colon carcinogenesis. 4193 hsa-mir-203 Arthritis, Rheumatoid 21279994 elevated levels of miR-203 lead to increased secretion of MMP-1 and IL-6 via the NF-kB pathway and thereby contribute to the activated phenotype of synovial fibroblasts in RA. 4194 hsa-mir-155 Inflammation 21282106 Elevated miR-155 promotes inflammation in cystic fibrosis by driving hyper-expression of interleukin-8. 4195 hsa-mir-155 Cystic Fibrosis 21282106 Elevated miR-155 promotes inflammation in cystic fibrosis by driving hyper-expression of interleukin-8. 4196 hsa-mir-24-1 Inflammation 21282569 Role of miR-204 in the regulation of apoptosis, ER stress response, and inflammation in human trabecular meshwork cells. 4197 hsa-mir-24-2 Inflammation 21282569 Role of miR-204 in the regulation of apoptosis, ER stress response, and inflammation in human trabecular meshwork cells. 4198 hsa-mir-199a-1 Liver Cirrhosis 21283674 In both the mouse and human studies, the expression levels of miR-199a, 199a*, 200a, and 200b were positively and significantly correlated to the progressed liver fibrosis. 4199 hsa-mir-199a-2 Liver Cirrhosis 21283674 In both the mouse and human studies, the expression levels of miR-199a, 199a*, 200a, and 200b were positively and significantly correlated to the progressed liver fibrosis. 4200 hsa-mir-200a Liver Cirrhosis 21283674 In both the mouse and human studies, the expression levels of miR-199a, 199a*, 200a, and 200b were positively and significantly correlated to the progressed liver fibrosis. 4201 hsa-mir-200b Liver Cirrhosis 21283674 In both the mouse and human studies, the expression levels of miR-199a, 199a*, 200a, and 200b were positively and significantly correlated to the progressed liver fibrosis. 4202 hsa-mir-106b Colonic Neoplasms 21283757 Butyrate-induced p21 protein expression was dampened by treatment with a miR-106b mimic. 4203 hsa-mir-200a Pancreatic Neoplasms 21285251 DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism. 4204 hsa-mir-33a Inflammation 21285396 miR-33 reduces RIP140 coactivator activity for NF-kB, which is supported by the reduction in NF-kB reporter activity and the inflammatory potential in macrophages. 4205 hsa-mir-33b Inflammation 21285396 miR-33 reduces RIP140 coactivator activity for NF-kB, which is supported by the reduction in NF-kB reporter activity and the inflammatory potential in macrophages. 4206 hsa-mir-335 Breast Neoplasms 21289068 MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer. 4207 hsa-mir-145 Lung Neoplasms 21289483 MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1. 4208 hsa-mir-141 Esophageal Neoplasms 21289630 MicroRNA-141 confers resistance to cisplatin-induced apoptosis by targeting YAP1 in human esophageal squamous cell carcinoma. 4209 hsa-let-7a-1 Head and Neck Neoplasms 21292542 MicroRNA let-7a represses chemoresistance and tumourigenicity in head and neck cancer via stem-like properties ablation. 4210 hsa-let-7a-2 Head and Neck Neoplasms 21292542 MicroRNA let-7a represses chemoresistance and tumourigenicity in head and neck cancer via stem-like properties ablation. 4211 hsa-let-7a-3 Head and Neck Neoplasms 21292542 MicroRNA let-7a represses chemoresistance and tumourigenicity in head and neck cancer via stem-like properties ablation. 4212 hsa-mir-200b Neoplasms 21292642 Depletion of miR-200 in arsenite-transformed cells involved induction of the EMT-inducing transcription factors ZEB1 (zinc-finger E-box-binding homeobox factor 1) and ZEB2 and increased methylation of miR-200 promoters. 4213 hsa-mir-193a Carcinoma, Squamous Cell 21293058 miR-193a-5p, expression of which was repressed by p63, was activated by proapoptotic p73 isoforms in both normal cells and tumor cells in vivo. 4214 hsa-mir-196a-1 Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4215 hsa-mir-196a-2 Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4216 hsa-mir-200a Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4217 hsa-mir-200b Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4218 hsa-mir-200c Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4219 hsa-mir-338 Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4220 hsa-mir-126 Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4221 hsa-mir-31 Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4222 hsa-mir-98 Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4223 hsa-let-7g Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4224 hsa-mir-7-1 Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4225 hsa-mir-7-2 Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4226 hsa-mir-7-3 Gastrointestinal Neoplasms 21293479 In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7. 4227 hsa-mir-200c Carcinoma, Squamous Cell 21294122 MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells. 4228 hsa-mir-200c Head and Neck Neoplasms 21294122 MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells. 4229 hsa-mir-221 Carcinoma, Hepatocellular 21295551 Serum miR-221, upregulated in HCC, can provide predictive significance for prognosis of HCC patients. 4230 hsa-mir-1-1 Parkinson Disease 21295623 miR-1, miR-22* and miR-29 expression levels allowed to distinguish non-treated PD from healthy subjects, miR-16-2*, miR-26a2* and miR30a differentiated treated from untreated patients. 4231 hsa-mir-1-2 Parkinson Disease 21295623 miR-1, miR-22* and miR-29 expression levels allowed to distinguish non-treated PD from healthy subjects, miR-16-2*, miR-26a2* and miR30a differentiated treated from untreated patients. 4232 hsa-mir-22 Parkinson Disease 21295623 miR-1, miR-22* and miR-29 expression levels allowed to distinguish non-treated PD from healthy subjects, miR-16-2*, miR-26a2* and miR30a differentiated treated from untreated patients. 4233 hsa-mir-29a Parkinson Disease 21295623 miR-1, miR-22* and miR-29 expression levels allowed to distinguish non-treated PD from healthy subjects, miR-16-2*, miR-26a2* and miR30a differentiated treated from untreated patients. 4234 hsa-mir-29b-1 Parkinson Disease 21295623 miR-1, miR-22* and miR-29 expression levels allowed to distinguish non-treated PD from healthy subjects, miR-16-2*, miR-26a2* and miR30a differentiated treated from untreated patients. 4235 hsa-mir-29b-2 Parkinson Disease 21295623 miR-1, miR-22* and miR-29 expression levels allowed to distinguish non-treated PD from healthy subjects, miR-16-2*, miR-26a2* and miR30a differentiated treated from untreated patients. 4236 hsa-mir-29c Parkinson Disease 21295623 miR-1, miR-22* and miR-29 expression levels allowed to distinguish non-treated PD from healthy subjects, miR-16-2*, miR-26a2* and miR30a differentiated treated from untreated patients. 4237 hsa-mir-16-2 Parkinson Disease 21295623 miR-1, miR-22* and miR-29 expression levels allowed to distinguish non-treated PD from healthy subjects, miR-16-2*, miR-26a2* and miR30a differentiated treated from untreated patients. 4238 hsa-mir-26a-2 Parkinson Disease 21295623 miR-1, miR-22* and miR-29 expression levels allowed to distinguish non-treated PD from healthy subjects, miR-16-2*, miR-26a2* and miR30a differentiated treated from untreated patients. 4239 hsa-mir-30a Parkinson Disease 21295623 miR-1, miR-22* and miR-29 expression levels allowed to distinguish non-treated PD from healthy subjects, miR-16-2*, miR-26a2* and miR30a differentiated treated from untreated patients. 4240 hsa-mir-155 Leukemia, Lymphocytic, Chronic, B-Cell 21296997 MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia. 4241 hsa-mir-100 Carcinoma, Hepatocellular 21298008 recurence related 4242 hsa-mir-99a Carcinoma, Hepatocellular 21298008 recurence related 4243 hsa-mir-99b Carcinoma, Hepatocellular 21298008 recurence related 4244 hsa-mir-125b-1 Carcinoma, Hepatocellular 21298008 recurence related 4245 hsa-mir-125b-2 Carcinoma, Hepatocellular 21298008 recurence related 4246 hsa-mir-378a Carcinoma, Hepatocellular 21298008 recurence related 4247 hsa-mir-129-1 Carcinoma, Hepatocellular 21298008 miR-129-5p recurence related 4248 hsa-mir-129-2 Carcinoma, Hepatocellular 21298008 miR-129-5p recurence related 4249 hsa-mir-125a Carcinoma, Hepatocellular 21298008 miR-125a-5p recurence related 4250 hsa-mir-497 Carcinoma, Hepatocellular 21298008 recurence related 4251 hsa-mir-22 Carcinoma, Hepatocellular 21298008 recurence related 4252 hsa-mir-140 Carcinoma, Hepatocellular 21298008 miR-140-3p recurence related 4253 hsa-mir-145 Carcinoma, Hepatocellular 21298008 recurence related 4254 hsa-mir-221 Carcinoma, Hepatocellular 21298008 recurence related 4255 hsa-mir-195 Carcinoma, Hepatocellular 21298008 recurence related 4256 hsa-mir-27a Carcinoma, Hepatocellular 21298008 recurence related 4257 hsa-mir-24-1 Carcinoma, Hepatocellular 21298008 recurence related 4258 hsa-mir-24-2 Carcinoma, Hepatocellular 21298008 recurence related 4259 hsa-mir-96 Carcinoma, Hepatocellular 21298008 recurence related 4260 hsa-mir-21 Carcinoma, Hepatocellular 21298008 recurence related 4261 hsa-mir-18a Carcinoma, Hepatocellular 21298008 recurence related 4262 hsa-mir-23a Carcinoma, Hepatocellular 21298008 recurence related 4263 hsa-mir-18b Carcinoma, Hepatocellular 21298008 recurence related 4264 hsa-mir-142 Carcinoma, Hepatocellular 21298008 miR-142-3p recurence related 4265 hsa-mir-362 Carcinoma, Hepatocellular 21298008 miR-362-3p recurence related 4266 hsa-mir-1202 Carcinoma, Hepatocellular 21298008 recurence related 4267 hsa-let-7e Carcinoma, Hepatocellular 21298008 recurence related 4268 hsa-let-7f-1 Carcinoma, Hepatocellular 21298008 recurence related 4269 hsa-let-7f-2 Carcinoma, Hepatocellular 21298008 recurence related 4270 hsa-mir-191 Carcinoma, Hepatocellular 21298008 recurence related 4271 hsa-mir-107 Carcinoma, Hepatocellular 21298008 recurence related 4272 hsa-mir-148a Carcinoma, Hepatocellular 21298008 recurence related 4273 hsa-mir-222 Carcinoma, Hepatocellular 21298008 recurence related 4274 hsa-mir-103a-1 Carcinoma, Hepatocellular 21298008 recurence related 4275 hsa-mir-103a-2 Carcinoma, Hepatocellular 21298008 recurence related 4276 hsa-mir-126 Carcinoma, Hepatocellular 21298008 miR-126* recurence related 4277 hsa-mir-425 Carcinoma, Hepatocellular 21298008 recurence related 4278 hsa-mir-203 Carcinoma, Squamous Cell 21299870 MicroRNA-203 inhibits cell proliferation by repressing DeltaNp63 expression in human esophageal squamous cell carcinoma. 4279 hsa-mir-203 Esophageal Neoplasms 21299870 MicroRNA-203 inhibits cell proliferation by repressing DeltaNp63 expression in human esophageal squamous cell carcinoma. 4280 hsa-mir-206 Breast Neoplasms 21302623 miR-206 may suppress invasion and migration of MDA-MB-231 cells in vitro partly via regulating actin cytoskeleton remodelling such as filopodia formation 4281 hsa-mir-1-1 Hypertrophy 21303526 The downregulation of miR-1, miR-133a, and upregulation of miR-21 can be reversed by one single upstream regulator, SRF. 4282 hsa-mir-1-2 Hypertrophy 21303526 The downregulation of miR-1, miR-133a, and upregulation of miR-21 can be reversed by one single upstream regulator, SRF. 4283 hsa-mir-133a-1 Hypertrophy 21303526 The downregulation of miR-1, miR-133a, and upregulation of miR-21 can be reversed by one single upstream regulator, SRF. 4284 hsa-mir-133a-2 Hypertrophy 21303526 The downregulation of miR-1, miR-133a, and upregulation of miR-21 can be reversed by one single upstream regulator, SRF. 4285 hsa-mir-21 Hypertrophy 21303526 The downregulation of miR-1, miR-133a, and upregulation of miR-21 can be reversed by one single upstream regulator, SRF. 4286 hsa-mir-638 Lung Neoplasms 21303527 We found the upregulation of microRNA-638 and microRNA-923 in bostrycin-treated lung adenocarcinoma cells 4287 hsa-mir-1-1 Urinary Bladder Neoplasms 21304530 The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. 4288 hsa-mir-1-2 Urinary Bladder Neoplasms 21304530 The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. 4289 hsa-mir-133a-1 Urinary Bladder Neoplasms 21304530 The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. 4290 hsa-mir-133a-2 Urinary Bladder Neoplasms 21304530 The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. 4291 hsa-mir-126 Gastrointestinal Neoplasms 21304604 miR-126 is a novel miRNA that targets SOX2, and PLAC1 may be a novel downstream target gene of SOX2 in gastric cancer cells. These findings suggest that aberrant over-expression of miR-126 and consequent SOX2 down-regulation may contribute to gastric carcinogenesis. 4292 hsa-mir-125b-1 Prostatic Neoplasms 21308711 miR-125b suppresses MUC1 translation in LNCaP cells and that an anti-sense miR-125b upregulates expression of MUC1 protein. In addition, stable expression of miR-125b in DU145 cells resulted in decreases in MUC1 levels. 4293 hsa-mir-125b-2 Prostatic Neoplasms 21308711 miR-125b suppresses MUC1 translation in LNCaP cells and that an anti-sense miR-125b upregulates expression of MUC1 protein. In addition, stable expression of miR-125b in DU145 cells resulted in decreases in MUC1 levels. 4294 hsa-mir-218-1 Cervical Intraepithelial Neoplasia 21309487 infection with high-risk HPV lowered the expression of miR-218 and that down-regulation of miR-218 was involved in the pathogenesis of cervical cancer 4295 hsa-mir-218-2 Cervical Intraepithelial Neoplasia 21309487 infection with high-risk HPV lowered the expression of miR-218 and that down-regulation of miR-218 was involved in the pathogenesis of cervical cancer 4296 hsa-let-7b Pre-Eclampsia 21309633 Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b. 4297 hsa-mir-128-1 Pre-Eclampsia 21309633 Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b. 4298 hsa-mir-128-2 Pre-Eclampsia 21309633 Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b. 4299 hsa-mir-133b Pre-Eclampsia 21309633 Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b. 4300 hsa-mir-182 Pre-Eclampsia 21309633 Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b. 4301 hsa-mir-302a Pre-Eclampsia 21309633 Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b. 4302 hsa-mir-302b Pre-Eclampsia 21309633 Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b. 4303 hsa-mir-302c Pre-Eclampsia 21309633 Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b. 4304 hsa-mir-302d Pre-Eclampsia 21309633 Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b. 4305 hsa-mir-302e Pre-Eclampsia 21309633 Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b. 4306 hsa-mir-302f Pre-Eclampsia 21309633 Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b. 4307 hsa-mir-21 Pre-Eclampsia 21309633 Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b. 4308 hsa-mir-155 Inflammation 21310411 HUVECs highly expressed miR-155 may co-target AT1R and Ets-1 while miR-221/222 targets Ets-1, which indirectly regulate the expression of several inflammatory molecules of ECs, and therefore attenuate the adhesion of Jurkat T cells to activated HUVECs and reduce HUVECs migration. These findings present possible therapeutic targets in atherosclerosis. 4309 hsa-mir-221 Inflammation 21310411 HUVECs highly expressed miR-155 may co-target AT1R and Ets-1 while miR-221/222 targets Ets-1, which indirectly regulate the expression of several inflammatory molecules of ECs, and therefore attenuate the adhesion of Jurkat T cells to activated HUVECs and reduce HUVECs migration. These findings present possible therapeutic targets in atherosclerosis. 4310 hsa-mir-222 Inflammation 21310411 HUVECs highly expressed miR-155 may co-target AT1R and Ets-1 while miR-221/222 targets Ets-1, which indirectly regulate the expression of several inflammatory molecules of ECs, and therefore attenuate the adhesion of Jurkat T cells to activated HUVECs and reduce HUVECs migration. These findings present possible therapeutic targets in atherosclerosis. 4311 hsa-mir-542 Neuroblastoma 21310526 MicroRNA-542-5p as a novel tumor suppressor in neuroblastoma. 4312 hsa-mir-29c Diabetes Mellitus 21310958 MicroRNA-29c is a signature MicroRNA under high glucose conditions which targets sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy. 4313 hsa-mir-199a-1 Carcinoma, Hepatocellular 21316602 Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma 4314 hsa-mir-199a-2 Carcinoma, Hepatocellular 21316602 Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma 4315 hsa-mir-199b Carcinoma, Hepatocellular 21316602 Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma 4316 hsa-mir-125a Hepatitis B 21317190 hsa-miR-125a-5p, was found to interact with the viral sequence and to suppress the reporter activity markedly. 4317 hsa-mir-17 Mesothelioma 21317924 Hsa-miR-17* was significantly upregulated and hsa-miR-30c was significantly downregulated by Onconase treatment in all cell lines 4318 hsa-mir-30c-1 Mesothelioma 21317924 Hsa-miR-17* was significantly upregulated and hsa-miR-30c was significantly downregulated by Onconase treatment in all cell lines 4319 hsa-mir-30c-2 Mesothelioma 21317924 Hsa-miR-17* was significantly upregulated and hsa-miR-30c was significantly downregulated by Onconase treatment in all cell lines 4320 hsa-mir-21 Prostatic Neoplasms 21317927 MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4 4321 hsa-mir-34a Carcinoma, Non-Small-Cell Lung 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 4322 hsa-mir-34a Breast Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 4323 hsa-mir-34a Colorectal Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 4324 hsa-mir-199a-1 Carcinoma, Non-Small-Cell Lung 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 4325 hsa-mir-199a-1 Breast Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 4326 hsa-mir-199a-1 Colorectal Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 4327 hsa-mir-199a-2 Carcinoma, Non-Small-Cell Lung 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 4328 hsa-mir-199a-2 Breast Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 4329 hsa-mir-199a-2 Colorectal Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 4330 hsa-mir-199b Carcinoma, Non-Small-Cell Lung 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 4331 hsa-mir-199b Breast Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 4332 hsa-mir-199b Colorectal Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 4333 hsa-mir-124-1 Breast Neoplasms 21318219 Genetic variants (SNP rs1042538 A/T) at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. 4334 hsa-mir-124-2 Breast Neoplasms 21318219 Genetic variants (SNP rs1042538 A/T) at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. 4335 hsa-mir-124-3 Breast Neoplasms 21318219 Genetic variants (SNP rs1042538 A/T) at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. 4336 hsa-mir-492 Hepatoblastoma 21319197 MicroRNA-492 is processed from the keratin 19 gene and up-regulated in metastatic hepatoblastoma. 4337 hsa-mir-499a Esophageal Neoplasms 21319225 SNP (rs3746444 A/G): Significantly increased CSCC risks were found to be associated with G allele of rs3746444 4338 hsa-mir-146a Esophageal Neoplasms 21319225 SNP (rs2910164 G/C): Significantly increased CSCC risks were found to be associated with G allele of rs2910164 4339 hsa-mir-499a Carcinoma, Squamous Cell 21319225 SNP (rs3746444 A/G): Significantly increased CSCC risks were found to be associated with G allele of rs3746444 4340 hsa-mir-146a Carcinoma, Squamous Cell 21319225 SNP (rs2910164 G/C): Significantly increased CSCC risks were found to be associated with G allele of rs2910164 4341 hsa-mir-30d Carcinoma, Hepatocellular 21319996 miR-30d and miR-151 were amplified in ~50% of Hepatitis B Virus-Associated HCC tumor tissues 4342 hsa-mir-151a Carcinoma, Hepatocellular 21319996 miR-30d and miR-151 were amplified in ~50% of Hepatitis B Virus-Associated HCC tumor tissues 4343 hsa-mir-1224 Neoplasms 21320120 Lipopolysaccharide-induced miR-1224 negatively regulates tumour necrosis factor-alpha gene expression by modulating Sp1. 4344 hsa-mir-204 Hypertension 21321078 Reestablishing miR-204 expression should be explored as a potential new therapy for this disease 4345 hsa-mir-101-1 Glioblastoma 21321380 miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis. 4346 hsa-mir-101-2 Glioblastoma 21321380 miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis. 4347 hsa-mir-499a Ovarian Neoplasms 21321636 miR-449b and miR-34c on inducing down-regulation of cell cycle-related proteins and cycle arrests in SKOV3-ipl cell, an ovarian cancer cell line. 4348 hsa-mir-34c Ovarian Neoplasms 21321636 miR-449b and miR-34c on inducing down-regulation of cell cycle-related proteins and cycle arrests in SKOV3-ipl cell, an ovarian cancer cell line. 4349 hsa-mir-203 Leukemia, Myeloid, Acute 21323860 The frequent hsa-miR-203 methylation in lymphoid malignancies suggested a pathogenetic role of hsa-miR-203 methylation. 4350 hsa-mir-517a Carcinoma, Hepatocellular 21324318 miR-517a is an oncogenic miRNA that promotes tumor progression. There is rationale for developing therapies that miRNA 517 for patients with HCC. 4351 hsa-mir-21 Breast Neoplasms 21326627 miR-21 Expression in Pregnancy-Associated Breast Cancer: A Possible Marker of Poor Prognosis. 4352 hsa-mir-1-1 Colorectal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4353 hsa-mir-1-1 Gastrointestinal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4354 hsa-mir-1-1 Endometrial Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4355 hsa-mir-124-1 Colorectal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4356 hsa-mir-124-1 Gastrointestinal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4357 hsa-mir-124-1 Endometrial Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4358 hsa-mir-124-2 Colorectal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4359 hsa-mir-124-2 Gastrointestinal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4360 hsa-mir-124-2 Endometrial Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4361 hsa-mir-124-3 Colorectal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4362 hsa-mir-124-3 Gastrointestinal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4363 hsa-mir-124-3 Endometrial Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4364 hsa-mir-148a Colorectal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4365 hsa-mir-148a Gastrointestinal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4366 hsa-mir-148a Endometrial Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4367 hsa-mir-152 Colorectal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4368 hsa-mir-152 Gastrointestinal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4369 hsa-mir-152 Endometrial Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4370 hsa-mir-18b Colorectal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4371 hsa-mir-18b Gastrointestinal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4372 hsa-mir-18b Endometrial Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4373 hsa-mir-200a Colorectal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4374 hsa-mir-200a Gastrointestinal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4375 hsa-mir-200a Endometrial Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4376 hsa-mir-208a Colorectal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4377 hsa-mir-208a Gastrointestinal Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4378 hsa-mir-208a Endometrial Neoplasms 21327300 Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a; 4379 hsa-mir-21 Neoplasms 21328460 miR-21 downregulates the tumor suppressor P12(CDK2AP1) and Stimulates Cell Proliferation and Invasion. 4380 hsa-mir-451a Carcinoma, Non-Small-Cell Lung 21329503 Upregulation of microRNA-451 increases cisplatin sensitivity of non-small cell lung cancer cell line (A549). 4381 hsa-mir-132 Pancreatic Neoplasms 21329664 miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor. 4382 hsa-mir-212 Pancreatic Neoplasms 21329664 miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor. 4383 hsa-mir-34b Colorectal Neoplasms 21329882 MK5 regulates translation of Myc, since it is required for expression of miR-34b and miR-34c that bind to the 3'UTR of MYC. MK5 activates miR-34b/c expression via phosphorylation of FoxO3a, thereby promoting nuclear localization of FoxO3a and enabling it to induce miR-34b/c expression and arrest proliferation. Expression of MK5 in turn is directly activated by Myc, forming a negative feedback loop. 4384 hsa-mir-34c Colorectal Neoplasms 21329882 MK5 regulates translation of Myc, since it is required for expression of miR-34b and miR-34c that bind to the 3'UTR of MYC. MK5 activates miR-34b/c expression via phosphorylation of FoxO3a, thereby promoting nuclear localization of FoxO3a and enabling it to induce miR-34b/c expression and arrest proliferation. Expression of MK5 in turn is directly activated by Myc, forming a negative feedback loop. 4385 hsa-mir-205 Carcinoma, Renal Cell 21330408 MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer. 4386 hsa-mir-21 Endometrial Neoplasms 21330826 Highly increased maspin expression corresponds with up-regulation of miR-21 in endometrial cancer 4387 hsa-let-7a-1 Myelodysplastic Syndromes 21332710 dysregulated 4388 hsa-let-7a-2 Myelodysplastic Syndromes 21332710 dysregulated 4389 hsa-let-7a-3 Myelodysplastic Syndromes 21332710 dysregulated 4390 hsa-let-7b Myelodysplastic Syndromes 21332710 dysregulated 4391 hsa-let-7c Myelodysplastic Syndromes 21332710 dysregulated 4392 hsa-let-7d Myelodysplastic Syndromes 21332710 dysregulated 4393 hsa-let-7e Myelodysplastic Syndromes 21332710 dysregulated 4394 hsa-let-7f-1 Myelodysplastic Syndromes 21332710 dysregulated 4395 hsa-let-7f-2 Myelodysplastic Syndromes 21332710 dysregulated 4396 hsa-let-7g Myelodysplastic Syndromes 21332710 dysregulated 4397 hsa-let-7i Myelodysplastic Syndromes 21332710 dysregulated 4398 hsa-mir-181a-1 Myelodysplastic Syndromes 21332710 dysregulated 4399 hsa-mir-181a-2 Myelodysplastic Syndromes 21332710 dysregulated 4400 hsa-mir-181b-2 Myelodysplastic Syndromes 21332710 dysregulated 4401 hsa-mir-181c Myelodysplastic Syndromes 21332710 dysregulated 4402 hsa-mir-181d Myelodysplastic Syndromes 21332710 dysregulated 4403 hsa-mir-29a Aortic Aneurysm, Thoracic 21334170 dysregulated 4404 hsa-mir-29b-1 Aortic Aneurysm, Thoracic 21334170 dysregulated 4405 hsa-mir-29b-2 Aortic Aneurysm, Thoracic 21334170 dysregulated 4406 hsa-mir-29c Aortic Aneurysm, Thoracic 21334170 dysregulated 4407 hsa-mir-30a Aortic Aneurysm, Thoracic 21334170 dysregulated 4408 hsa-mir-30b Aortic Aneurysm, Thoracic 21334170 dysregulated 4409 hsa-mir-30c-1 Aortic Aneurysm, Thoracic 21334170 dysregulated 4410 hsa-mir-30c-2 Aortic Aneurysm, Thoracic 21334170 dysregulated 4411 hsa-mir-30d Aortic Aneurysm, Thoracic 21334170 dysregulated 4412 hsa-mir-30e Aortic Aneurysm, Thoracic 21334170 dysregulated 4413 hsa-mir-16-1 Carcinoma, Hepatocellular 21336967 P-glycoprotein enhances radiation-induced apoptotic cell death through the regulation of miR-16 and Bcl-2 expressions in hepatocellular carcinoma cells. 4414 hsa-mir-16-2 Carcinoma, Hepatocellular 21336967 P-glycoprotein enhances radiation-induced apoptotic cell death through the regulation of miR-16 and Bcl-2 expressions in hepatocellular carcinoma cells. 4415 hsa-mir-124-1 Arthritis, Rheumatoid 21339227 miR-124a is a key miRNA in the post-transcriptional regulatory mechanisms of RA synoviocytes, and has a therapeutic potential. 4416 hsa-mir-124-2 Arthritis, Rheumatoid 21339227 miR-124a is a key miRNA in the post-transcriptional regulatory mechanisms of RA synoviocytes, and has a therapeutic potential. 4417 hsa-mir-124-3 Arthritis, Rheumatoid 21339227 miR-124a is a key miRNA in the post-transcriptional regulatory mechanisms of RA synoviocytes, and has a therapeutic potential. 4418 hsa-mir-34b Lung Neoplasms 21339737 A microRNA, miR-34b, that suppresses the expression of alpha4 through specific binding to the 3'-untranslated region of alpha4 is downregulated in transformed or human lung tumors. 4419 hsa-mir-520b Breast Neoplasms 21343296 miR-520b regulates migration of breast cancer cells through targeting hepatitis B X-interacting protein and interleukin-8. 4420 hsa-mir-375 Gastrointestinal Neoplasms 21343377 A high frequency recurrence and poor survival were observed in GC cases with high level of hsa-miR-375 and low level of hsa-miR-142-5p (P < 0.001),indicating that the combination of hsa-miR-375 and hsa-miR-142-5p as a predictor of disease progression has the potential to predict recurrence risk for GC patients 4421 hsa-mir-142 Gastrointestinal Neoplasms 21343377 A high frequency recurrence and poor survival were observed in GC cases with high level of hsa-miR-375 and low level of hsa-miR-142-5p (P < 0.001),indicating that the combination of hsa-miR-375 and hsa-miR-142-5p as a predictor of disease progression has the potential to predict recurrence risk for GC patients 4422 hsa-mir-375 Stomach Neoplasms 21343377 A high frequency recurrence and poor survival were observed in gastric cancer cases with high level of hsa-miR-375 and low level of hsa-miR-142-5p (P < 0.001). The results indicate that the combination of hsa-miR-375 and hsa-miR-142-5p as a predictor of disease progression has the potential to predict recurrence risk for GC patients. 4423 hsa-mir-142 Stomach Neoplasms 21343377 A high frequency recurrence and poor survival were observed in gastric cancer cases with high level of hsa-miR-375 and low level of hsa-miR-142-5p (P < 0.001). The results indicate that the combination of hsa-miR-375 and hsa-miR-142-5p as a predictor of disease progression has the potential to predict recurrence risk for GC patients. 4424 hsa-mir-196a-2 Urinary Bladder Neoplasms 21345130 Our results showed that the heterozygous genotype of rs11614913 (hsa-mir-196a2 C>T rs11614913) was higher in cases than controls but the results were marginally significant (p=0.055; odds ratio, 1.44). 4425 hsa-mir-196b Urinary Bladder Neoplasms 21345130 Our results showed that the heterozygous genotype of rs11614913 (hsa-mir-196a2 C>T rs11614913) was higher in cases than controls but the results were marginally significant (p=0.055; odds ratio, 1.44). 4426 hsa-mir-200c Ovarian Neoplasms 21345725 miR-200c has potential as a predictor of survival, and is a biomarker of relapse, in stage I EOC. 4427 hsa-mir-146a Gastrointestinal Neoplasms 21347720 MicroRNA-146a is down-regulated in gastric cancer and regulates cell proliferation and apoptosis. 4428 hsa-mir-142 Pancreatic Neoplasms 21347785 patients with high miR-142-5p and miR-204 expression had significantly longer survival times than those with low miR-142-5p (P = 0.0077) and miR-204 (P = 0.0054) expression in the gemcitabine-treated group. 4429 hsa-mir-204 Pancreatic Neoplasms 21347785 patients with high miR-142-5p and miR-204 expression had significantly longer survival times than those with low miR-142-5p (P = 0.0077) and miR-204 (P = 0.0054) expression in the gemcitabine-treated group. 4430 hsa-let-7a-1 Gastrointestinal Neoplasms 21349817 let-7a is significant in suppressing gastric cancer growth in vivo and in vitro and provided the first evidence that RAB40C is negatively regulated by let-7a at the post-transcriptional level via binding to the 3'-untranslated region of RAB40C mRNA in gastric cancer. 4431 hsa-mir-145 Prostatic Neoplasms 21349819 this is the first report documenting that downregulation of miR-145 is through DNA methylation and p53 mutation pathways in prostate cancer. 4432 hsa-mir-195 Breast Neoplasms 21350001 both miR-195 and miR-497 play important inhibitory roles in breast cancer malignancy and may be the potential therapeutic and diagnostic targets. 4433 hsa-mir-497 Breast Neoplasms 21350001 both miR-195 and miR-497 play important inhibitory roles in breast cancer malignancy and may be the potential therapeutic and diagnostic targets. 4434 hsa-mir-34c Prostatic Neoplasms 21351256 miR-34c is downregulated in prostate cancer and exerts tumor suppressive functions. 4435 hsa-mir-145 Carcinoma, Squamous Cell 21351259 miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma. 4436 hsa-mir-133a-1 Carcinoma, Squamous Cell 21351259 miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma. 4437 hsa-mir-133a-2 Carcinoma, Squamous Cell 21351259 miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma. 4438 hsa-mir-133b Carcinoma, Squamous Cell 21351259 miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma. 4439 hsa-mir-200b Diabetic Retinopathy 21357793 MicroRNA-200b Regulates Vascular Endothelial Growth Factor-Mediated Alterations in Diabetic Retinopathy. 4440 hsa-mir-224 Medulloblastoma 21358093 A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas. 4441 hsa-mir-452 Medulloblastoma 21358093 A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas. 4442 hsa-mir-182 Medulloblastoma 21358093 A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas. 4443 hsa-mir-183 Medulloblastoma 21358093 A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas. 4444 hsa-mir-96 Medulloblastoma 21358093 A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas. 4445 hsa-mir-148a Medulloblastoma 21358093 A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas. 4446 hsa-mir-193a Medulloblastoma 21358093 A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas. 4447 hsa-mir-193b Medulloblastoma 21358093 A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas. 4448 hsa-mir-17 Mesothelioma 21358347 miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated 4449 hsa-mir-18a Mesothelioma 21358347 miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated 4450 hsa-mir-20a Mesothelioma 21358347 miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated 4451 hsa-mir-25 Mesothelioma 21358347 miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated 4452 hsa-mir-106a Mesothelioma 21358347 miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated 4453 hsa-mir-106b Mesothelioma 21358347 miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated 4454 hsa-mir-20b Mesothelioma 21358347 miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated 4455 hsa-mir-182 Mesothelioma 21358347 dysregulated 4456 hsa-mir-214 Mesothelioma 21358347 dysregulated 4457 hsa-mir-497 Mesothelioma 21358347 dysregulated 4458 hsa-mir-19b-1 Mesothelioma 21358347 miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated 4459 hsa-mir-19b-2 Mesothelioma 21358347 miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated 4460 hsa-mir-92a-1 Mesothelioma 21358347 miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated 4461 hsa-mir-92a-2 Mesothelioma 21358347 miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated 4462 hsa-mir-7-1 Mesothelioma 21358347 dysregulated 4463 hsa-mir-7-2 Mesothelioma 21358347 dysregulated 4464 hsa-mir-7-3 Mesothelioma 21358347 dysregulated 4465 hsa-mir-451a Carcinoma, Non-Small-Cell Lung 21358675 MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14). 4466 hsa-mir-29b-1 Breast Neoplasms 21359530 miR-29b regulates migration of human breast cancer cells. 4467 hsa-mir-29b-2 Breast Neoplasms 21359530 miR-29b regulates migration of human breast cancer cells. 4468 hsa-mir-569 Lupus Erythematosus, Systemic 21360505 rs1057233 alters a target sequence for microRNA hsa-miR-569 (miR-569). 4469 hsa-mir-145 Prostatic Neoplasms 21360565 SWAP70, actin-binding protein, function as an oncogene targeting tumor-suppressive miR-145 in prostate cancer. 4470 hsa-mir-16-1 Laryngeal Neoplasms 21360639 MicroRNA-16 targets zyxin and promotes cell motility in human laryngeal carcinoma cell line HEp-2. 4471 hsa-mir-16-2 Laryngeal Neoplasms 21360639 MicroRNA-16 targets zyxin and promotes cell motility in human laryngeal carcinoma cell line HEp-2. 4472 hsa-let-7a-2 Lung Neoplasms 21365266 9-cis-RA, all-trans-RA,lithium chloride and CEBP might play important regulatory roles in let-7a2 gene expression in A549 cells 4473 hsa-mir-124-1 Stomach Neoplasms 21365509 Significant associations were found between hypermethylation of hsa-miR-124a and tumor size, differentiation, lymphatic metastasis, and invasion depth(P<0.01). 4474 hsa-mir-124-2 Stomach Neoplasms 21365509 Significant associations were found between hypermethylation of hsa-miR-124a and tumor size, differentiation, lymphatic metastasis, and invasion depth(P<0.01). 4475 hsa-mir-124-3 Stomach Neoplasms 21365509 Significant associations were found between hypermethylation of hsa-miR-124a and tumor size, differentiation, lymphatic metastasis, and invasion depth(P<0.01). 4476 hsa-mir-145 Adenocarcinoma 21365617 Up-regulation of microRNA-145 promotes differentiation by repressing OCT4 in human endometrial adenocarcinoma cells. 4477 hsa-mir-144 Tuberculosis, Pulmonary 21367459 Modulation of T cell cytokine production by miR-144* with elevated expression in patients with pulmonary tuberculosis. 4478 hsa-mir-34a Leukemia 21367750 miR-34a induces the down-regulation of both E2F1 and B-Myb oncogenes in leukemic cells. 4479 hsa-mir-17 Obesity 21367929 Expression of two miRNAs (miR-17-5p and miR-132) differed significantly between obese and nonobese omental fat (P = 0.048 and P = 0.016). 4480 hsa-mir-132 Obesity 21367929 Expression of two miRNAs (miR-17-5p and miR-132) differed significantly between obese and nonobese omental fat (P = 0.048 and P = 0.016). 4481 hsa-mir-203 Prostatic Neoplasms 21368580 MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines. 4482 hsa-let-7a-1 Breast Neoplasms 21368581 Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFbeta-induced oncomiR miRNA-181a. 4483 hsa-let-7a-2 Breast Neoplasms 21368581 Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFbe-induced oncomiR miRNA-181a. 4484 hsa-let-7a-3 Breast Neoplasms 21368581 Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFbeta-induced oncomiR miRNA-181a. 4485 hsa-mir-181a-1 Breast Neoplasms 21368581 Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFbeta-induced oncomiR miRNA-181a. 4486 hsa-mir-181a-2 Breast Neoplasms 21368581 Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFbeta-induced oncomiR miRNA-181a. 4487 hsa-mir-101-1 Nasopharyngeal Neoplasms 21368858 Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98. 4488 hsa-mir-101-2 Nasopharyngeal Neoplasms 21368858 Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98. 4489 hsa-mir-26a-1 Nasopharyngeal Neoplasms 21368858 Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98. 4490 hsa-mir-26a-2 Nasopharyngeal Neoplasms 21368858 Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98. 4491 hsa-mir-98 Nasopharyngeal Neoplasms 21368858 Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98. 4492 hsa-mir-200a Lupus Erythematosus, Systemic 21372198 The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls. 4493 hsa-mir-200b Lupus Erythematosus, Systemic 21372198 The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls. 4494 hsa-mir-200c Lupus Erythematosus, Systemic 21372198 The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls. 4495 hsa-mir-205 Lupus Erythematosus, Systemic 21372198 The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls. 4496 hsa-mir-429 Lupus Erythematosus, Systemic 21372198 The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls. 4497 hsa-mir-192 Lupus Erythematosus, Systemic 21372198 The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls. 4498 hsa-mir-141 Lupus Erythematosus, Systemic 21372198 The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls. 4499 hsa-mir-21 Ischemia 21373187 deregulated 4500 hsa-mir-29b-1 Ischemia 21373187 deregulated 4501 hsa-mir-29b-2 Ischemia 21373187 deregulated 4502 hsa-mir-30b Ischemia 21373187 deregulated 4503 hsa-mir-125a Retinoblastoma 21373755 We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions. 4504 hsa-mir-30c-2 Retinoblastoma 21373755 We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions. 4505 hsa-mir-497 Retinoblastoma 21373755 We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions. 4506 hsa-mir-491 Retinoblastoma 21373755 We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions. 4507 hsa-mir-181b-1 Retinoblastoma 21373755 We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions. 4508 hsa-mir-181b-2 Retinoblastoma 21373755 We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions. 4509 hsa-mir-18a Nasopharyngeal Neoplasms 21373758 overexpressed 4510 hsa-mir-34b Nasopharyngeal Neoplasms 21373758 underexpressed 4511 hsa-mir-34c Nasopharyngeal Neoplasms 21373758 underexpressed 4512 hsa-let-7a-1 Nasopharyngeal Neoplasms 21373758 underexpressed 4513 hsa-let-7a-2 Nasopharyngeal Neoplasms 21373758 underexpressed 4514 hsa-let-7a-3 Nasopharyngeal Neoplasms 21373758 underexpressed 4515 hsa-let-7b Nasopharyngeal Neoplasms 21373758 underexpressed 4516 hsa-let-7c Nasopharyngeal Neoplasms 21373758 underexpressed 4517 hsa-let-7d Nasopharyngeal Neoplasms 21373758 underexpressed 4518 hsa-let-7e Nasopharyngeal Neoplasms 21373758 underexpressed 4519 hsa-let-7f-1 Nasopharyngeal Neoplasms 21373758 underexpressed 4520 hsa-let-7f-2 Nasopharyngeal Neoplasms 21373758 underexpressed 4521 hsa-let-7g Nasopharyngeal Neoplasms 21373758 underexpressed 4522 hsa-let-7i Nasopharyngeal Neoplasms 21373758 underexpressed 4523 hsa-mir-195 Breast Neoplasms 21375733 dysregulated 4524 hsa-mir-182 Breast Neoplasms 21375733 dysregulated 4525 hsa-mir-183 Breast Neoplasms 21375733 dysregulated 4526 hsa-mir-125b-1 Breast Neoplasms 21375733 dysregulated 4527 hsa-mir-125b-2 Breast Neoplasms 21375733 dysregulated 4528 hsa-mir-21 Pancreatic Neoplasms 21376256 Bcl-2 Upregulation Induced by miR-21 Via a Direct Interaction Is Associated with Apoptosis and Chemoresistance in MIA PaCa-2 Pancreatic Cancer Cells. 4529 hsa-mir-221 Prostatic Neoplasms 21378318 miR-221 Is Down-regulated in TMPRSS2:ERG Fusion-positive Prostate Cancer. 4530 hsa-mir-222 Prostatic Neoplasms 21378318 miR-221 Is Down-regulated in TMPRSS2:ERG Fusion-positive Prostate Cancer. 4531 hsa-mir-1-1 Head and Neck Neoplasms 21378409 miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. 4532 hsa-mir-1-2 Head and Neck Neoplasms 21378409 miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. 4533 hsa-mir-1-1 Carcinoma, Squamous Cell 21378409 miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. 4534 hsa-mir-1-2 Carcinoma, Squamous Cell 21378409 miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. 4535 hsa-mir-34b Carcinoma, Non-Small-Cell Lung 21383543 DNA hypermethylation of microRNA-34b/c has prognostic value for stage ⅿnon-small cell lung cancer. 4536 hsa-mir-34c Carcinoma, Non-Small-Cell Lung 21383543 DNA hypermethylation of microRNA-34b/c has prognostic value for stage ⅿnon-small cell lung cancer. 4537 hsa-mir-199a-1 Testicular Neoplasms 21383689 PODXL is a downstream effector mediating the action of miR199a-5p. This report identifies DNA methylation, miR-199a dysregulation and PODXL as critical factors in tumor malignancy. 4538 hsa-mir-199a-2 Testicular Neoplasms 21383689 PODXL is a downstream effector mediating the action of miR199a-5p. This report identifies DNA methylation, miR-199a dysregulation and PODXL as critical factors in tumor malignancy. 4539 hsa-mir-99a Neoplasms 21383697 miR-99a-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways. 4540 hsa-mir-92a-1 Lymphoma 21383985 Down-Regulated Plasma miR-92a Levels in Non-Hodgkin's Lymphoma. 4541 hsa-mir-92a-2 Lymphoma 21383985 Down-Regulated Plasma miR-92a Levels in Non-Hodgkin's Lymphoma. 4542 hsa-mir-181a-1 Lupus Erythematosus, Systemic 21385555 miR-181-a was significantly downregulated in SLE pediatrics as compared to healthy controls. 4543 hsa-mir-181a-2 Lupus Erythematosus, Systemic 21385555 miR-181-a was significantly downregulated in SLE pediatrics as compared to healthy controls. 4544 hsa-mir-9-1 Glioblastoma 21385897 miR-9 suppresses mesenchymal differentiation in glioblastoma by downregulating expression of JAK kinases and inhibiting activation of STAT3. 4545 hsa-mir-9-2 Glioblastoma 21385897 miR-9 suppresses mesenchymal differentiation in glioblastoma by downregulating expression of JAK kinases and inhibiting activation of STAT3. 4546 hsa-mir-9-3 Glioblastoma 21385897 miR-9 suppresses mesenchymal differentiation in glioblastoma by downregulating expression of JAK kinases and inhibiting activation of STAT3. 4547 hsa-mir-218-1 Nasopharyngeal Neoplasms 21385904 miR-218 Suppresses Nasopharyngeal Cancer Progression through Downregulation of Survivin and the SLIT2-ROBO1 Pathway. 4548 hsa-mir-218-2 Nasopharyngeal Neoplasms 21385904 miR-218 Suppresses Nasopharyngeal Cancer Progression through Downregulation of Survivin and the SLIT2-ROBO1 Pathway. 4549 hsa-mir-1-1 Myocardial Infarction 21386882 miR-1, miR-29b and miR-98 dysregulated. 4550 hsa-mir-1-2 Myocardial Infarction 21386882 miR-1, miR-29b and miR-98 dysregulated. 4551 hsa-mir-29b-1 Myocardial Infarction 21386882 miR-1, miR-29b and miR-98 dysregulated. 4552 hsa-mir-29b-2 Myocardial Infarction 21386882 miR-1, miR-29b and miR-98 dysregulated. 4553 hsa-mir-98 Myocardial Infarction 21386882 miR-1, miR-29b and miR-98 dysregulated. 4554 hsa-mir-210 Pre-Eclampsia 21388516 Elevated levels of hypoxia-inducible microRNA-210 in preeclampsia. 4555 hsa-mir-18a Urinary Bladder Neoplasms 21388952 Specific deletion of p53 in urothelial cells is associated with specific overexpression of miR-18a and miR-19a and down-regulation of miR-107. 4556 hsa-mir-19a Urinary Bladder Neoplasms 21388952 Specific deletion of p53 in urothelial cells is associated with specific overexpression of miR-18a and miR-19a and down-regulation of miR-107. 4557 hsa-mir-107 Urinary Bladder Neoplasms 21388952 Specific deletion of p53 in urothelial cells is associated with specific overexpression of miR-18a and miR-19a and down-regulation of miR-107. 4558 hsa-mir-195 Colorectal Neoplasms 21390519 Downregulation of miR-195 correlates with lymph node metastasis and poor prognosis in colorectal cancer. 4559 hsa-mir-301a Breast Neoplasms 21393507 miR-301 as a crucial oncogene in human breast cancer that acts through multiple pathways and mechanisms to promote nodal or distant relapses. 4560 hsa-mir-301b Breast Neoplasms 21393507 miR-301 as a crucial oncogene in human breast cancer that acts through multiple pathways and mechanisms to promote nodal or distant relapses. 4561 hsa-mir-133a-1 Urinary Bladder Neoplasms 21396852 MiR-133a induces apoptosis through direct regulation of GSTP1 in bladder cancer cell lines. 4562 hsa-mir-146a Osteoarthritis 21397669 miR-146a controls knee joint homeostasis and OA associated algesia by balancing inflammatory responses in cartilage and synovium with pain-related factors in glial cells. Hence, miR-146a may be useful for the treatment of both cartilage regeneration and pain symptoms caused by OA (osteoarthritis). 4563 hsa-mir-193a Leukemia, Myeloid, Acute 21399664 MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia. 4564 hsa-mir-125b-1 Colorectal Neoplasms 21399871 miR-125b is directly involved in cancer progression and is associated with poor prognosis in human colorectal cancer. Our findings suggest that miR-125b could be an important prognostic indicator for colorectal cancer patients. 4565 hsa-mir-125b-2 Colorectal Neoplasms 21399871 miR-125b is directly involved in cancer progression and is associated with poor prognosis in human colorectal cancer. Our findings suggest that miR-125b could be an important prognostic indicator for colorectal cancer patients. 4566 hsa-mir-34a Breast Neoplasms 21399894 increased expression of miR-34a in an acquired model of docetaxel resistance in breast cancer. 4567 hsa-mir-204 Endometrial Neoplasms 21400511 Dysregulation of microRNA-204 mediates migration and invasion of endometrial cancer by regulating FOXC1. 4568 hsa-mir-16-1 Carcinoma, Non-Small-Cell Lung 21400525 miR-16 levels in tumor samples may be a prognostic marker in NSCLC. 4569 hsa-mir-16-2 Carcinoma, Non-Small-Cell Lung 21400525 miR-16 levels in tumor samples may be a prognostic marker in NSCLC. 4570 hsa-mir-221 Liver Failure 21400558 We identified miR-221 as a potent posttranscriptional regulator of FAS-induced apoptosis. miR-221 may serve as a potential therapeutic target for the treatment of hepatitis and liver failure. 4571 hsa-mir-223 Multiple Myeloma 21401705 Expression of CD19 and lack of miR-223 distinguish extramedullary plasmacytoma from multiple myeloma. 4572 hsa-mir-200a Lung Neoplasms 21403400 The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. 4573 hsa-mir-200b Lung Neoplasms 21403400 The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. 4574 hsa-mir-200c Lung Neoplasms 21403400 The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. 4575 hsa-mir-155 Mycosis Fungoides 21406335 upregulated in tumor stage MF compared to benign inflammatory dermatoses. 4576 hsa-mir-93 Mycosis Fungoides 21406335 upregulated in tumor stage MF compared to benign inflammatory dermatoses. 4577 hsa-mir-92a-1 Mycosis Fungoides 21406335 upregulated in tumor stage MF compared to benign inflammatory dermatoses. 4578 hsa-mir-92a-2 Mycosis Fungoides 21406335 upregulated in tumor stage MF compared to benign inflammatory dermatoses. 4579 hsa-mir-31 Breast Neoplasms 21406558 Activation of miR-31 function in already-established metastases elicits metastatic regression. 4580 hsa-mir-16-1 Colorectal Neoplasms 21406606 Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways. 4581 hsa-mir-16-2 Colorectal Neoplasms 21406606 Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways. 4582 hsa-mir-21 Colorectal Neoplasms 21406606 Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways. 4583 hsa-mir-26b Colorectal Neoplasms 21406606 Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways. 4584 hsa-mir-27b Colorectal Neoplasms 21406606 Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways. 4585 hsa-mir-93 Colorectal Neoplasms 21406606 Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways. 4586 hsa-mir-203 Colorectal Neoplasms 21406606 Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways. 4587 hsa-mir-19b-1 Colorectal Neoplasms 21406606 Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways. 4588 hsa-mir-19b-2 Colorectal Neoplasms 21406606 Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways. 4589 hsa-mir-145 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. 4590 hsa-mir-203 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. 4591 hsa-mir-15b Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. 4592 hsa-mir-21 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. 4593 hsa-mir-486 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. 4594 hsa-let-7a-1 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. 4595 hsa-let-7a-2 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. 4596 hsa-let-7a-3 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. 4597 hsa-mir-21 Pancreatic Neoplasms 21408027 Anti-Tumor Activity of a Novel Compound-CDF Is Mediated by Regulating miR-21, miR-200, and PTEN in Pancreatic Cancer. 4598 hsa-mir-200a Pancreatic Neoplasms 21408027 Anti-Tumor Activity of a Novel Compound-CDF Is Mediated by Regulating miR-21, miR-200, and PTEN in Pancreatic Cancer. 4599 hsa-mir-21 Pancreatic Neoplasms 21408027 in gemcitabine-resistant (MIAPaCa-2) PC cells containing high proportion of CSCs consistent with increased miR-21 and decreased miR-200. 4600 hsa-mir-200a Pancreatic Neoplasms 21408027 in gemcitabine-resistant (MIAPaCa-2) PC cells containing high proportion of CSCs consistent with increased miR-21 and decreased miR-200. 4601 hsa-mir-200b Pancreatic Neoplasms 21408027 in gemcitabine-resistant (MIAPaCa-2) PC cells containing high proportion of CSCs consistent with increased miR-21 and decreased miR-200. 4602 hsa-mir-200c Pancreatic Neoplasms 21408027 in gemcitabine-resistant (MIAPaCa-2) PC cells containing high proportion of CSCs consistent with increased miR-21 and decreased miR-200. 4603 hsa-mir-34a Leukemia, Lymphocytic, Chronic, B-Cell 21408091 upregulation 4604 hsa-mir-155 Leukemia, Lymphocytic, Chronic, B-Cell 21408091 upregulation 4605 hsa-mir-342 Leukemia, Lymphocytic, Chronic, B-Cell 21408091 miR-342-3p upregulation 4606 hsa-mir-103a-1 Leukemia, Lymphocytic, Chronic, B-Cell 21408091 downregulation 4607 hsa-mir-103a-2 Leukemia, Lymphocytic, Chronic, B-Cell 21408091 downregulation 4608 hsa-mir-181a-1 Leukemia, Lymphocytic, Chronic, B-Cell 21408091 downregulation 4609 hsa-mir-181a-2 Leukemia, Lymphocytic, Chronic, B-Cell 21408091 downregulation 4610 hsa-mir-181b-1 Leukemia, Lymphocytic, Chronic, B-Cell 21408091 downregulation 4611 hsa-mir-181b-2 Leukemia, Lymphocytic, Chronic, B-Cell 21408091 downregulation 4612 hsa-mir-200c Breast Neoplasms 21409395 Both miR-200c and miR-429, two members of the miR-200 family were expressed in the luminal and basal type of breast cancer in contrast to malignant myoepithelioma. 4613 hsa-mir-429 Breast Neoplasms 21409395 Both miR-200c and miR-429, two members of the miR-200 family were expressed in the luminal and basal type of breast cancer in contrast to malignant myoepithelioma. 4614 hsa-let-7c Breast Neoplasms 21409395 let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells 4615 hsa-mir-126 Breast Neoplasms 21409395 let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells 4616 hsa-mir-127 Breast Neoplasms 21409395 let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells 4617 hsa-mir-143 Breast Neoplasms 21409395 let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells 4618 hsa-mir-145 Breast Neoplasms 21409395 let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells 4619 hsa-mir-146b Breast Neoplasms 21409395 let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells 4620 hsa-mir-200c Breast Neoplasms 21409395 Two members of the miR-200 family (miR-200c and miR-429) were predominantly luminal. 4621 hsa-mir-429 Breast Neoplasms 21409395 Two members of the miR-200 family (miR-200c and miR-429) were predominantly luminal. 4622 hsa-mir-125b-1 Breast Neoplasms 21409395 let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells 4623 hsa-mir-125b-2 Breast Neoplasms 21409395 let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells 4624 hsa-mir-199a-1 Breast Neoplasms 21409395 let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells 4625 hsa-mir-199a-2 Breast Neoplasms 21409395 let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells 4626 hsa-mir-21 Colorectal Neoplasms 21412018 High miR-21 expression was significantly associated with venous invasion, liver metastasis and tumor stage.The overall (OS) and disease-free survival (DFS) rates of patients with high miR-21 expression were significantly worse than those of patients with low miR-21 expression. 4627 hsa-mir-155 Colorectal Neoplasms 21412018 High miR-155 expression was significantly correlated with lymph node metastases. The overall (OS) and disease-free survival (DFS) rates of patients with high miR-155 expression were also significantly worse than those in patients with low miR-155 expression. 4628 hsa-mir-125b-1 Psoriasis 21412257 MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2. 4629 hsa-mir-125b-2 Psoriasis 21412257 MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2. 4630 hsa-let-7b Liposarcoma 21412931 Let-7 MicroRNA and HMGA2 levels of expression are not inversely linked in adipocytic tumors: Analysis of 56 lipomas and liposarcomas with molecular cytogenetic data. 4631 hsa-let-7g Liposarcoma 21412931 Let-7 MicroRNA and HMGA2 levels of expression are not inversely linked in adipocytic tumors: Analysis of 56 lipomas and liposarcomas with molecular cytogenetic data. 4632 hsa-mir-486 Stomach Neoplasms 21415212 Genomic Loss of miR-486 Regulates Tumor Progression and the OLFM4 Anti-apoptotic Factor in Gastric Cancer. 4633 hsa-mir-204 Stomach Neoplasms 21416062 MiR-204, which was predicted to target ezrin, was downregulated in gastric cancer cells and gastric carcinomas. MiR-204 inhibited ezrin expression, Ras activation, cell growth and cell migration 4634 hsa-mir-1-1 Hypertrophy 21418519 IGF-1 deficiency retards AAC-induced cardiac hypertrophic and contractile changes via alleviating downregulation of miR-1 and miR-133a in response to left ventricular pressure overload. 4635 hsa-mir-1-2 Hypertrophy 21418519 IGF-1 deficiency retards AAC-induced cardiac hypertrophic and contractile changes via alleviating downregulation of miR-1 and miR-133a in response to left ventricular pressure overload. 4636 hsa-mir-133a-1 Hypertrophy 21418519 IGF-1 deficiency retards AAC-induced cardiac hypertrophic and contractile changes via alleviating downregulation of miR-1 and miR-133a in response to left ventricular pressure overload. 4637 hsa-mir-133a-2 Hypertrophy 21418519 IGF-1 deficiency retards AAC-induced cardiac hypertrophic and contractile changes via alleviating downregulation of miR-1 and miR-133a in response to left ventricular pressure overload. 4638 hsa-mir-449a Stomach Neoplasms 21418558 miR-449 inhibits cell proliferation and is down-regulated in gastric cancer. 4639 hsa-mir-449b Stomach Neoplasms 21418558 miR-449 inhibits cell proliferation and is down-regulated in gastric cancer. 4640 hsa-mir-449c Stomach Neoplasms 21418558 miR-449 inhibits cell proliferation and is down-regulated in gastric cancer. 4641 hsa-mir-10b Glioblastoma 21419107 MicroRNA-10b induces glioma cell invasion by modulating MMP-14 and uPAR expression via HOXD10. 4642 hsa-mir-99b Esophageal Neoplasms 21420070 The expression of three miRNAs (miR-99b and miR-199a_3p and _5p) was associated with the presence of lymph node metastasis. 4643 hsa-mir-193a Esophageal Neoplasms 21420070 The expression of three miRNAs (miR-99b and miR-199a_3p and _5p) was associated with the presence of lymph node metastasis. 4644 hsa-mir-328 Myopia 21421876 SNPs rs644242 and rs662702 had marginal significance (p=0.063) and further analyses showed that these SNPs were associated with extreme myopia. The OR for extreme myopia was 2.1 (empirical p=0.007) for the CC genotype at SNP rs662702 at 3' UTR. The functional assay for SNP rs662702 demonstrated that the C allele had a significantly lower expression level than the T allele (P=0.0001). SNP rs662702 was predicted to be located in the microRNA-328 binding site, which may explain the differential allelic effect on gene expression. 4645 hsa-mir-34b Huntington Disease 21421997 Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease. 4646 hsa-mir-137 Carcinoma, Squamous Cell 21425146 MicroRNA-137 promoter methylation is associated with poorer overall survival in patients with squamous cell carcinoma of the head and neck. 4647 hsa-mir-1-1 Muscular Dystrophy, Duchenne 21425469 miR-1, miR-133, and miR-206 are new and valuable biomarkers for the diagnosis of DMD and possibly also for monitoring the outcomes of therapeutic interventions in humans 4648 hsa-mir-1-2 Muscular Dystrophy, Duchenne 21425469 miR-1, miR-133, and miR-206 are new and valuable biomarkers for the diagnosis of DMD and possibly also for monitoring the outcomes of therapeutic interventions in humans 4649 hsa-mir-133a-1 Muscular Dystrophy, Duchenne 21425469 miR-1, miR-133, and miR-206 are new and valuable biomarkers for the diagnosis of DMD and possibly also for monitoring the outcomes of therapeutic interventions in humans 4650 hsa-mir-133a-2 Muscular Dystrophy, Duchenne 21425469 miR-1, miR-133, and miR-206 are new and valuable biomarkers for the diagnosis of DMD and possibly also for monitoring the outcomes of therapeutic interventions in humans 4651 hsa-mir-133b Muscular Dystrophy, Duchenne 21425469 miR-1, miR-133, and miR-206 are new and valuable biomarkers for the diagnosis of DMD and possibly also for monitoring the outcomes of therapeutic interventions in humans 4652 hsa-mir-205 Esophageal Neoplasms 21426561 MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells. 4653 hsa-mir-205 Carcinoma, Squamous Cell 21426561 MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells. 4654 hsa-mir-21 Obesity 21426570 mir-21 is up-regulated in subcutaneous adipose tissue in human obesity 4655 hsa-mir-21 Carcinoma, Squamous Cell 21426775 Anti-sense miRNA-21 oligonucleotide inhibits Tb 3.1 human tongue squamous cell carcinoma growth in vitro.] 4656 hsa-mir-95 Colorectal Neoplasms 21427358 MicroRNA-95 Promotes Cell Proliferation and Targets Sorting Nexin 1 in Human Colorectal Carcinoma. 4657 hsa-mir-143 Osteosarcoma 21427707 MicroRNA-143 Regulates Human Osteosarcoma Metastasis by Regulating Matrix Metalloprotease-13 Expression. 4658 hsa-mir-101-1 Prostatic Neoplasms 21430074 Enforced Expression of miR-101 inhibits prostate cancer cell growth by modulating cyclooxygenase-2 pathway in vivo. 4659 hsa-mir-101-2 Prostatic Neoplasms 21430074 Enforced Expression of miR-101 inhibits prostate cancer cell growth by modulating cyclooxygenase-2 pathway in vivo. 4660 hsa-mir-205 Prostatic Neoplasms 21431706 Differentially expressed between androgen-dependent and androgen-independent metastatic prostate cancer cells 4661 hsa-mir-200c Prostatic Neoplasms 21431706 Differentially expressed between androgen-dependent and androgen-independent metastatic prostate cancer cells 4662 hsa-mir-211 Melanoma 21435193 Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor. 4663 hsa-mir-381 Glioblastoma 21435336 Interaction of hsa-miR-381 and glioma suppressor LRRC4 is involved in glioma growth. 4664 hsa-mir-202 Endometriosis 21436257 up-regulated in endometriomas compared with endometrium. 4665 hsa-mir-193a Endometriosis 21436257 miR-193a-3p and miR-193a-5p up-regulated in endometriomas compared with endometrium. 4666 hsa-mir-29c Endometriosis 21436257 up-regulated in endometriomas compared with endometrium. 4667 hsa-mir-708 Endometriosis 21436257 up-regulated in endometriomas compared with endometrium. 4668 hsa-mir-509-3 Endometriosis 21436257 miR-509-3-5p up-regulated in endometriomas compared with endometrium. 4669 hsa-mir-574 Endometriosis 21436257 miR-574-3p up-regulated in endometriomas compared with endometrium. 4670 hsa-mir-485 Endometriosis 21436257 miR-485-3p up-regulated in endometriomas compared with endometrium. 4671 hsa-mir-100 Endometriosis 21436257 up-regulated in endometriomas compared with endometrium. 4672 hsa-mir-720 Endometriosis 21436257 up-regulated in endometriomas compared with endometrium. 4673 hsa-mir-504 Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. 4674 hsa-mir-141 Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. 4675 hsa-mir-429 Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. 4676 hsa-mir-203 Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. 4677 hsa-mir-10a Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. 4678 hsa-mir-200b Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. 4679 hsa-mir-873 Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. 4680 hsa-mir-200c Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. 4681 hsa-mir-200a Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. 4682 hsa-mir-449b Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. 4683 hsa-mir-375 Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. 4684 hsa-mir-34c Endometriosis 21436257 miR-34c-5p down-regulated in endometriomas compared with endometrium. 4685 hsa-mir-126 Carcinoma, Non-Small-Cell Lung 21439283 miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5. 4686 hsa-mir-143 Diabetes Mellitus, Type 2 21441927 Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. 4687 hsa-mir-16-1 Leukemia-Lymphoma, Adult T-Cell 21441948 Triptolide inhibits the proliferation of cells from lymphocytic leukemic cell lines in association with downregulation of NF-kB activity and miR-16-1(*). 4688 hsa-mir-125b-1 Breast Neoplasms 21444677 miR-125b is Methylated and Functions as A Tumor Suppressor by Regulating the ETS1 proto-oncogene in Human Invasive Breast Cancer. 4689 hsa-mir-125b-2 Breast Neoplasms 21444677 miR-125b is Methylated and Functions as A Tumor Suppressor by Regulating the ETS1 proto-oncogene in Human Invasive Breast Cancer. 4690 hsa-mir-141 Colorectal Neoplasms 21445232 High levels of plasma miR-141 predicted poor survival in both cohorts and that miR-141 was an independent prognostic factor for advanced colon cancer. 4691 hsa-mir-204 Prostatic Neoplasms 21446014 PDEF expression is regulated via a functional microRNA-204 (miR-204) binding site within the 3'UTR. Furthermore, we demonstrate the biologic significance of miR-204 expression and that miR-204 is over-expressed in human prostate cancer specimens. 4692 hsa-mir-34a Radiation Injuries 21448283 Differing responses to ionizing radiation (IR) of young and adult mice were related to miR-34a. miR-34a may be a novel indicator, mediator and target of radiation injury, radio-sensitivity and radioprotection. 4693 hsa-mir-200a Barrett Esophagus 21448356 miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus. 4694 hsa-mir-200b Barrett Esophagus 21448356 miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus. 4695 hsa-mir-200c Barrett Esophagus 21448356 miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus. 4696 hsa-mir-141 Barrett Esophagus 21448356 miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus. 4697 hsa-mir-429 Barrett Esophagus 21448356 miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus. 4698 hsa-mir-328 Carcinoma, Non-Small-Cell Lung 21448905 MicroRNA-328 is associated with (non-small) cell lung cancer (NSCLC) brain metastasis and mediates NSCLC migration. 4699 hsa-mir-143 Esophageal Neoplasms 21453382 The high levels of expression of mature MIR143 and mature MIR145 were associated with recurrence of metastasis in ESCC patients.The high expression of mature MIR21 and mature MIR205 was associated with lymph node positivity in ESCC patients (P < 0.05). 4700 hsa-mir-145 Esophageal Neoplasms 21453382 The high levels of expression of mature MIR143 and mature MIR145 were associated with recurrence of metastasis in ESCC patients.The high expression of mature MIR21 and mature MIR205 was associated with lymph node positivity in ESCC patients (P < 0.05). 4701 hsa-mir-21 Esophageal Neoplasms 21453382 The high levels of expression of mature MIR143 and mature MIR145 were associated with recurrence of metastasis in ESCC patients.The high expression of mature MIR21 and mature MIR205 was associated with lymph node positivity in ESCC patients (P < 0.05). 4702 hsa-mir-205 Esophageal Neoplasms 21453382 The high levels of expression of mature MIR143 and mature MIR145 were associated with recurrence of metastasis in ESCC patients.The high expression of mature MIR21 and mature MIR205 was associated with lymph node positivity in ESCC patients (P < 0.05). 4703 hsa-mir-223 Esophageal Neoplasms 21453483 miR-223 regulates migration and invasion by targeting Artemin in human esophageal carcinoma. 4704 hsa-mir-203 Lymphoma 21454413 Epigenetic silencing of microRNA-203 dysregulates ABL1 expression and drives Helicobacter-associated gastric lymphomagenesis. 4705 hsa-mir-205 Melanoma 21454583 miR-205 suppresses melanoma cell proliferation and induces senescence via regulation of E2F1. 4706 hsa-mir-7-1 Neurofibromatosis 2 21454924 We found that miR-7 functions as a "tumor suppressor" by targeting proteins in three major oncogenic pathways - EGFR, Pak1, and Ack1. 4707 hsa-mir-7-2 Neurofibromatosis 2 21454924 We found that miR-7 functions as a "tumor suppressor" by targeting proteins in three major oncogenic pathways - EGFR, Pak1, and Ack1. 4708 hsa-mir-7-3 Neurofibromatosis 2 21454924 We found that miR-7 functions as a "tumor suppressor" by targeting proteins in three major oncogenic pathways - EGFR, Pak1, and Ack1. 4709 hsa-mir-148a Colorectal Neoplasms 21455217 MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer. 4710 hsa-mir-210 Sarcoma 21455991 Expression of microRNA 210 associates with poor survival and age of tumor onset of soft-tissue sarcoma patients. 4711 hsa-mir-221 Carcinoma, Hepatocellular 21458843 Deregulated expression of microRNA-221 with the potential for prognostic biomarkers in surgically resected hepatocellular carcinoma. 4712 hsa-mir-122 Carcinoma, Hepatocellular 21458843 Deregulated expression of microRNA-221 with the potential for prognostic biomarkers in surgically resected hepatocellular carcinoma. 4713 hsa-mir-34a Lymphoma, B-Cell 21460242 Myc-mediated repression of microRNA-34a promotes high grade transformation of B-cell lymphoma by dysregulation of FoxP1. 4714 hsa-mir-20a Leukemia, Lymphocytic, Chronic, B-Cell 21460253 circulating miR-20a correlates reliably with diagnosis-to-treatment time. 4715 hsa-mir-125b-1 Melanoma 21460750 the expression of miRNA-125b (miR-125b) was two-fold lower in malignant melanoma producing lymph node micrometastases than in nonmetastasizing tumors. MicroRNA miR-125b induces senescence in human melanoma cells.We propose that downregulation of miR-125b in an early cutaneous malignant melanoma can contribute to the increased metastatic capability of this tumor. 4716 hsa-mir-125b-2 Melanoma 21460750 the expression of miRNA-125b (miR-125b) was two-fold lower in malignant melanoma producing lymph node micrometastases than in nonmetastasizing tumors. MicroRNA miR-125b induces senescence in human melanoma cells.We propose that downregulation of miR-125b in an early cutaneous malignant melanoma can contribute to the increased metastatic capability of this tumor. 4717 hsa-mir-155 Breast Neoplasms 21460854 miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT. 4718 hsa-mir-203 Uterine Cervical Neoplasms 21461574 hypermethylation of miR-124a and miR-203 in the precursor lesions compared to the control samples 4719 hsa-mir-217 Pancreatic Neoplasms 21463235 altered expression 4720 hsa-mir-196a-1 Pancreatic Neoplasms 21463235 altered expression 4721 hsa-mir-196a-2 Pancreatic Neoplasms 21463235 altered expression 4722 hsa-mir-24-2 Breast Neoplasms 21463514 miR-24-2 controls H2AFX expression regardless of gene copy number alteration and induces apoptosis by targeting anti-apoptotic gene BCL-2: a potential for therapeutic intervention. 4723 hsa-mir-21 Pancreatic Neoplasms 21463919 over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype 4724 hsa-mir-200b Pancreatic Neoplasms 21463919 over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype 4725 hsa-mir-200c Pancreatic Neoplasms 21463919 over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype 4726 hsa-let-7a-1 Pancreatic Neoplasms 21463919 over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype 4727 hsa-let-7a-2 Pancreatic Neoplasms 21463919 over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype 4728 hsa-let-7a-3 Pancreatic Neoplasms 21463919 over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype 4729 hsa-let-7b Pancreatic Neoplasms 21463919 over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype 4730 hsa-let-7c Pancreatic Neoplasms 21463919 over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype 4731 hsa-mir-181a-1 Carcinoma, Hepatocellular 21464043 HBx promotes "stemness" by activating {beta}-catenin and epigenetic up-regulation of miR-181, both of which target EpCAM. 4732 hsa-mir-181a-2 Carcinoma, Hepatocellular 21464043 HBx promotes "stemness" by activating {beta}-catenin and epigenetic up-regulation of miR-181, both of which target EpCAM. 4733 hsa-mir-181b-1 Carcinoma, Hepatocellular 21464043 HBx promotes "stemness" by activating {beta}-catenin and epigenetic up-regulation of miR-181, both of which target EpCAM. 4734 hsa-mir-181b-2 Carcinoma, Hepatocellular 21464043 HBx promotes "stemness" by activating {beta}-catenin and epigenetic up-regulation of miR-181, both of which target EpCAM. 4735 hsa-mir-181c Carcinoma, Hepatocellular 21464043 HBx promotes "stemness" by activating {beta}-catenin and epigenetic up-regulation of miR-181, both of which target EpCAM. 4736 hsa-mir-181d Carcinoma, Hepatocellular 21464043 HBx promotes "stemness" by activating {beta}-catenin and epigenetic up-regulation of miR-181, both of which target EpCAM. 4737 hsa-mir-451a Leukemia-Lymphoma, Adult T-Cell 21464222 Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL. 4738 hsa-mir-9-1 Lung Neoplasms 21464588 miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFKB1. 4739 hsa-mir-9-2 Lung Neoplasms 21464588 miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFKB1. 4740 hsa-mir-9-3 Lung Neoplasms 21464588 miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFKB1. 4741 hsa-let-7g Lung Neoplasms 21464588 miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFKB1. 4742 hsa-mir-96 Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4743 hsa-mir-183 Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4744 hsa-mir-200b Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4745 hsa-mir-429 Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4746 hsa-mir-200c Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4747 hsa-mir-141 Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4748 hsa-mir-17 Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4749 hsa-mir-200a Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4750 hsa-mir-18a Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4751 hsa-mir-19a Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4752 hsa-mir-20a Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4753 hsa-mir-143 Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, downregulated. 4754 hsa-mir-145 Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, downregulated. 4755 hsa-mir-19b-1 Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4756 hsa-mir-19b-2 Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4757 hsa-mir-92a-1 Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4758 hsa-mir-92a-2 Urinary Bladder Neoplasms 21464941 Compared to matched histologically normal urothelium, upregulated. 4759 hsa-mir-210 Carcinoma, Renal Cell 21465485 Overexpression of miR-210, a downstream target of HIF1, causes centrosome amplification in renal carcinoma cells. 4760 hsa-mir-155 Melanoma 21466664 MicroRNA-155 Targets the SKI Gene in Human Melanoma Cell Lines 4761 hsa-mir-214 Melanoma 21468029 miR-214 is highly expressed in human melanomas and contributes to melanoma tumour progression through suppression of TFAP2C 4762 hsa-mir-21 Urinary Bladder Neoplasms 21468550 microRNA-21 modulates cell proliferation and sensitivity to doxorubicin in bladder cancer cells 4763 hsa-let-7a-1 Carcinoma, Non-Small-Cell Lung 21468581 Let-7a miRNAs were under-expressed in the blood of NSCLC patients, as well as NSCLC cells and NSCLC tissues, compared to normal controls. 4764 hsa-let-7a-2 Carcinoma, Non-Small-Cell Lung 21468581 Let-7a miRNAs were under-expressed in the blood of NSCLC patients, as well as NSCLC cells and NSCLC tissues, compared to normal controls. 4765 hsa-let-7a-3 Carcinoma, Non-Small-Cell Lung 21468581 Let-7a miRNAs were under-expressed in the blood of NSCLC patients, as well as NSCLC cells and NSCLC tissues, compared to normal controls. 4766 hsa-mir-146a Sjogren's Syndrome 21469088 Altered miR-146a expression in Sjogren's syndrome 4767 hsa-mir-139 Adrenocortical Carcinoma 21471143 ACCs (adrenocortical carcinomas) exhibited significantly lower levels of miR-139-3p (up to 8.49-fold, p<0.001), miR-675 (up to 23.25-fold, p<0.001) and miR-335 (up to 5.25-fold, p<0.001). 4768 hsa-mir-675 Adrenocortical Carcinoma 21471143 ACCs (adrenocortical carcinomas) exhibited significantly lower levels of miR-139-3p (up to 8.49-fold, p<0.001), miR-675 (up to 23.25-fold, p<0.001) and miR-335 (up to 5.25-fold, p<0.001). 4769 hsa-mir-375 Adrenocortical Carcinoma 21471143 ACCs (adrenocortical carcinomas) exhibited significantly lower levels of miR-139-3p (up to 8.49-fold, p<0.001), miR-675 (up to 23.25-fold, p<0.001) and miR-335 (up to 5.25-fold, p<0.001). 4770 hsa-mir-21 Breast Neoplasms 21471222 Upregulation of MIR-21 mediates resistance to trastuzumab therapy for breast cancer. 4771 hsa-mir-10b Glioblastoma 21471404 Human glioma growth is controlled by microRNA-10b 4772 hsa-mir-146a Carcinoma, Renal Cell 21472233 Carbamylated albumin stimulates microRNA-146, which is increased in human renal cell carcinoma. 4773 hsa-mir-146b Carcinoma, Renal Cell 21472233 Carbamylated albumin stimulates microRNA-146, which is increased in human renal cell carcinoma. 4774 hsa-mir-100 Endometrial Neoplasms 21472251 hsa-miR-100 and hsa-miR-99a were predicted to target ESR1, and hsa-miR-378 and hsa-miR-768-3p to target PGR. Hsa-miR-100 was significantly down-regulated in the estrogen-dependent endometrial cancer samples as compared to the estrogen-independent samples and thus has the potential to target ESR1. 4775 hsa-mir-378a Endometrial Neoplasms 21472251 hsa-miR-100 and hsa-miR-99a were predicted to target ESR1, and hsa-miR-378 and hsa-miR-768-3p to target PGR. Hsa-miR-100 was significantly down-regulated in the estrogen-dependent endometrial cancer samples as compared to the estrogen-independent samples and thus has the potential to target ESR1. 4776 hsa-mir-99a Endometrial Neoplasms 21472251 hsa-miR-100 and hsa-miR-99a were predicted to target ESR1, and hsa-miR-378 and hsa-miR-768-3p to target PGR. Hsa-miR-100 was significantly down-regulated in the estrogen-dependent endometrial cancer samples as compared to the estrogen-independent samples and thus has the potential to target ESR1. 4777 hsa-let-7g Lung Neoplasms 21472347 Precursor let-7g microRNA can supress A549 lung cancer cell migration. 4778 hsa-mir-483 Adrenocortical Carcinoma 21472710 miRs -100, -125b, and -195 were significantly down-regulated, whereas miR-483-5p was significantly up-regulated in malignant as compared with benign tumors. 4779 hsa-mir-100 Adrenocortical Carcinoma 21472710 miRs -100, -125b, and -195 were significantly down-regulated, whereas miR-483-5p was significantly up-regulated in malignant as compared with benign tumors. 4780 hsa-mir-195 Adrenocortical Carcinoma 21472710 miRs -100, -125b, and -195 were significantly down-regulated, whereas miR-483-5p was significantly up-regulated in malignant as compared with benign tumors. 4781 hsa-mir-125b-1 Adrenocortical Carcinoma 21472710 miRs -100, -125b, and -195 were significantly down-regulated, whereas miR-483-5p was significantly up-regulated in malignant as compared with benign tumors. 4782 hsa-mir-125b-2 Adrenocortical Carcinoma 21472710 miRs -100, -125b, and -195 were significantly down-regulated, whereas miR-483-5p was significantly up-regulated in malignant as compared with benign tumors. 4783 hsa-mir-15a Prostatic Neoplasms 21472816 The miR-15a-miR-16-1 locus is homozygously deleted in a subset of prostate cancers. 4784 hsa-mir-16-1 Prostatic Neoplasms 21472816 The miR-15a-miR-16-1 locus is homozygously deleted in a subset of prostate cancers. 4785 hsa-mir-146a Breast Neoplasms 21472990 Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. 4786 hsa-mir-146b Breast Neoplasms 21472990 Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. 4787 hsa-mir-1-1 Muscular Dystrophy, Duchenne 21479190 the serum levels of several muscle-specific miRNAs (miR-1, miR-133a and miR-206) are increased 4788 hsa-mir-1-2 Muscular Dystrophy, Duchenne 21479190 the serum levels of several muscle-specific miRNAs (miR-1, miR-133a and miR-206) are increased 4789 hsa-mir-133a-1 Muscular Dystrophy, Duchenne 21479190 the serum levels of several muscle-specific miRNAs (miR-1, miR-133a and miR-206) are increased 4790 hsa-mir-133a-2 Muscular Dystrophy, Duchenne 21479190 the serum levels of several muscle-specific miRNAs (miR-1, miR-133a and miR-206) are increased 4791 hsa-mir-206 Muscular Dystrophy, Duchenne 21479190 the serum levels of several muscle-specific miRNAs (miR-1, miR-133a and miR-206) are increased 4792 hsa-mir-145 Lung Neoplasms 21479367 microRNA-145 suppresses lung adenocarcinoma-initiating cell proliferation by targeting OCT4. 4793 hsa-mir-517a Urinary Bladder Neoplasms 21479368 Restoration of miR-517a expression induces cell apoptosis in bladder cancer cell lines. 4794 hsa-mir-373 Carcinoma, Hepatocellular 21481188 miR-373 can regulate cell cycle progression by targeting PPP6C transcripts and promotes the growth activity of hepatocellular carcinoma cells in vitro. This miRNA functions as an oncogene in hepatocellular carcinoma. 4795 hsa-mir-221 Neoplasms 21481725 miRNA-221/-222 control radiation sensitivity by regulating the PTEN/AKT pathway and can be explored as novel targets for radiosensitization. 4796 hsa-mir-222 Neoplasms 21481725 miRNA-221/-222 control radiation sensitivity by regulating the PTEN/AKT pathway and can be explored as novel targets for radiosensitization. 4797 hsa-mir-142 Carcinoma, Hepatocellular 21482222 MicroRNA-142-3p, a new regulator of RAC1, suppresses the migration and invasion of hepatocellular carcinoma cells. 4798 hsa-let-7a-1 Ovarian Neoplasms 21482675 rs12194974 (G>A), a SNP in a putative transcription factor binding site in the LIN28B promoter region (summary OR=0.90, 95% CI: 0.82-0.98; P=0.015). LIN28B LIN28B over-expression in epithelial ovarian cancer (EOC) contributes to tumorigenesis by repressing tumor suppressor let-7 expression. 4799 hsa-let-7a-2 Ovarian Neoplasms 21482675 rs12194974 (G>A), a SNP in a putative transcription factor binding site in the LIN28B promoter region (summary OR=0.90, 95% CI: 0.82-0.98; P=0.015). LIN28B LIN28B over-expression in epithelial ovarian cancer (EOC) contributes to tumorigenesis by repressing tumor suppressor let-7 expression. 4800 hsa-let-7a-3 Ovarian Neoplasms 21482675 rs12194974 (G>A), a SNP in a putative transcription factor binding site in the LIN28B promoter region (summary OR=0.90, 95% CI: 0.82-0.98; P=0.015). LIN28B LIN28B over-expression in epithelial ovarian cancer (EOC) contributes to tumorigenesis by repressing tumor suppressor let-7 expression. 4801 hsa-mir-126 Mesothelioma 21483773 Levels of miR-126 in serum, and its levels in patients' serum in association with a specific marker of MPM, SMRPs, correlate with subjects at high risk to develop malignant pleural mesothelioma (MPM). 4802 hsa-mir-196a-2 Breast Neoplasms 21483822 rs11614913 polymorphism:Overall, individuals with the TC/CC genotypes were associated with higher cancer risk than those with the TT genotype (OR?=?1.18, 95% CI?=?1.03-1.34, P<0.001 for heterogeneity test). In the stratified analyses, we observed that the CC genotype might modulate breast cancer risk (OR?=?1.11, 95%CI?=?1.01-1.23, P(heterogeneity)?=?0.210) and lung cancer risk (OR?=?1.25, 95%CI?=?1.06-1.46, P(heterogeneity)?=?0.958), comparing with the TC/TT genotype. Moreover, a significantly increased risk was found among Asian populations in a dominant model (TC/CC versus TT, OR?=?1.24, 95% CI?=?1.07-1.43, P(heterogeneity)?=?0.006). 4803 hsa-mir-196a-2 Lung Neoplasms 21483822 rs11614913 polymorphism:Overall, individuals with the TC/CC genotypes were associated with higher cancer risk than those with the TT genotype (OR?=?1.18, 95% CI?=?1.03-1.34, P<0.001 for heterogeneity test). In the stratified analyses, we observed that the CC genotype might modulate breast cancer risk (OR?=?1.11, 95%CI?=?1.01-1.23, P(heterogeneity)?=?0.210) and lung cancer risk (OR?=?1.25, 95%CI?=?1.06-1.46, P(heterogeneity)?=?0.958), comparing with the TC/TT genotype. Moreover, a significantly increased risk was found among Asian populations in a dominant model (TC/CC versus TT, OR?=?1.24, 95% CI?=?1.07-1.43, P(heterogeneity)?=?0.006). 4804 hsa-mir-20a Glioblastoma 21483847 miR-20a upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma. 4805 hsa-mir-106a Glioblastoma 21483847 miR-106aa upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma. 4806 hsa-mir-17 Glioblastoma 21483847 miR-17-5p upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma. 4807 hsa-mir-31 Glioblastoma 21483847 miR-31 downregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma. 4808 hsa-mir-222 Glioblastoma 21483847 miR-222 downregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma. 4809 hsa-mir-148a Glioblastoma 21483847 miR-148a upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma. 4810 hsa-mir-221 Glioblastoma 21483847 miR-221 downregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma. 4811 hsa-mir-146b Glioblastoma 21483847 miR-146b upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma. 4812 hsa-mir-200b Glioblastoma 21483847 miR-200b upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma. 4813 hsa-mir-193a Glioblastoma 21483847 miR-193a upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma. 4814 hsa-mir-221 Prostatic Neoplasms 21487968 MiR-221 expression affects invasion potential of human prostate carcinoma cell lines by targeting DVL2. 4815 hsa-mir-223 Carcinoma, Hepatocellular 21492514 microRNA-223 and its target gene oncogene c-myc have roles in hepatocellular carcinoma pathogenesis. 4816 hsa-mir-503 Carcinoma, Hepatocellular 21495032 microRNA-503 regulates metastatic function in hepatocellular cancer cell. 4817 hsa-mir-145 Lung Neoplasms 21496429 miR-145 Inhibits Lung Adenocarcinoma Stem Cells Proliferation by Targeting OCT4 Gene. 4818 hsa-mir-18a Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 4819 hsa-mir-18b Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 4820 hsa-mir-19a Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 4821 hsa-mir-19b-1 Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 4822 hsa-mir-19b-2 Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 4823 hsa-mir-22 Neoplasms 21502362 miR-22 represses cancer progression by inducing cellular senescence. 4824 hsa-mir-150 Lymphoma 21502955 microRNA-150 is a tumor suppressor in malignant lymphoma 4825 hsa-mir-183 Lung Neoplasms 21503569 microRNA-182 inhibits the proliferation and invasion of human lung adenocarcinoma cells through its effect on human cortical actin-associated protein. 4826 hsa-mir-20a Melanoma 21509659 significantly up-regulated in uveal melanomas compared with normal uveal tissues 4827 hsa-mir-106a Melanoma 21509659 significantly up-regulated in uveal melanomas compared with normal uveal tissues 4828 hsa-mir-17 Melanoma 21509659 significantly up-regulated in uveal melanomas compared with normal uveal tissues 4829 hsa-mir-21 Melanoma 21509659 significantly up-regulated in uveal melanomas compared with normal uveal tissues 4830 hsa-mir-34a Melanoma 21509659 significantly up-regulated in uveal melanomas compared with normal uveal tissues 4831 hsa-mir-145 Melanoma 21509659 significantly down-regulated in uveal melanomas compared with normal uveal tissues 4832 hsa-mir-204 Melanoma 21509659 significantly down-regulated in uveal melanomas compared with normal uveal tissues 4833 hsa-mir-26b Breast Neoplasms 21510944 MicroRNA-26b is underexpressed in human breast cancer and induces cell apoptosis by targeting SLC7A11. 4834 hsa-mir-451a Leukemia, Myelogenous, Chronic, BCR-ABL Positive 21511335 downregulated 4835 hsa-mir-192 Retinoblastoma 21511813 MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells. 4836 hsa-mir-21 Lung Neoplasms 21516486 High expression of serum miR-21 and tumor miR-200c associated with poor prognosis in patients with lung cancer 4837 hsa-mir-200c Lung Neoplasms 21516486 High expression of serum miR-21 and tumor miR-200c associated with poor prognosis in patients with lung cancer 4838 hsa-mir-663a Leukemia, Myeloid, Acute 21518431 Retinoic acid induces HL-60 cell differentiation via the upregulation of miR-663 4839 hsa-mir-143 Leukemia 21518477 miR-143 is differentially expressed of in Bone Marrow Cells between Acute Leukemia Patients and Normal People. 4840 hsa-mir-218-1 Urinary Bladder Neoplasms 21519788 miR-218 on the genomic loss region of chromosome 4p15.31 functions as a tumor suppressor in bladder cancer. 4841 hsa-mir-218-2 Urinary Bladder Neoplasms 21519788 miR-218 on the genomic loss region of chromosome 4p15.31 functions as a tumor suppressor in bladder cancer. 4842 hsa-mir-1-1 Hepatitis B 21520166 MiR-1 regulates the expression of several host genes to enhance HBV replication and reverse cancer cell phenotype, which is apparently beneficial for HBV replication. 4843 hsa-mir-1-2 Hepatitis B 21520166 MiR-1 regulates the expression of several host genes to enhance HBV replication and reverse cancer cell phenotype, which is apparently beneficial for HBV replication. 4844 hsa-mir-499a Tuberculosis, Pulmonary 21524676 There was no association between rs3746444 (in hsa-mir-499) and PTB risk (p = 0.118) in the Han population, but subjects carrying the C allele exhibited decreased PTB risk (odds ratio [OR] = 0.403 [95% confidence interval (95% CI) 0.278-0.583]). There was an association between rs3746444 and PTB in the Tibetan population, and individuals carrying the C allele exhibited increased PTB risk (OR = 1.870 [95% CI 1.218-2.871]). 4845 hsa-mir-146a Tuberculosis, Pulmonary 21524676 A polymorphism (rs2910164 G>C, in miR-146a) indicated an association with PTB risk in both Tibetan (p = 0.031) and Han (p = 0.000) populations. However, the role of the G allele of rs2910164, like the C allele in rs3746444, differed in the Tibetan (OR = 1.509, p < 0.05) and Han (OR = 0.575, p < 0.05) groups. 4846 hsa-mir-519d Carcinoma, Hepatocellular 21524841 MicroRNA-519d targets MKi67 and suppresses cell growth in the hepatocellular carcinoma cell line QGY-7703. 4847 hsa-mir-21 Sezary Syndrome 21525938 MicroRNA profiling reveals that miR-21, miR-486 and miR-214 are upregulated and involved in cell survival in Sezary Syndrome. 4848 hsa-mir-486 Sezary Syndrome 21525938 MicroRNA profiling reveals that miR-21, miR-486 and miR-214 are upregulated and involved in cell survival in Sezary Syndrome. 4849 hsa-mir-214 Sezary Syndrome 21525938 MicroRNA profiling reveals that miR-21, miR-486 and miR-214 are upregulated and involved in cell survival in Sezary Syndrome. 4850 hsa-mir-622 Stomach Neoplasms 21528065 Down-regulation of miR-622 in gastric cancer promotes cellular invasion and tumor metastasis by targeting ING1 gene. 4851 hsa-mir-146a Lupus Erythematosus, Systemic 21529448 Increased Expression in Peripheral Blood Mononuclear Cells in Patients with Systemic Lupus Erythematosus. 4852 hsa-mir-200a Ovarian Neoplasms 21529905 MicroRNA-200a inhibits CD133/1+ ovarian cancer stem cells migration and invasion by targeting E-cadherin repressor ZEB2. 4853 hsa-mir-146a Uterine Cervical Neoplasms 21529907 Polymorphism (rs2910164) of the pre-miR-146a is associated with risk of cervical cancer in a Chinese population. The subjects carrying GG homozygote had a 1.496-foldincreased risk than those carrying CG/CC genotypes. The carriers of GG genotype had obviously more reduced miR-146a expression level compared with the carriers of CC genotype. 4854 hsa-mir-9-1 Glioblastoma 21531766 ID4 Imparts Chemoresistance and Cancer Stemness to Glioma Cells by Derepressing miR-9*-Mediated Suppression of SOX2. 4855 hsa-mir-9-2 Glioblastoma 21531766 ID4 Imparts Chemoresistance and Cancer Stemness to Glioma Cells by Derepressing miR-9*-Mediated Suppression of SOX2. 4856 hsa-mir-9-3 Glioblastoma 21531766 ID4 Imparts Chemoresistance and Cancer Stemness to Glioma Cells by Derepressing miR-9*-Mediated Suppression of SOX2. 4857 hsa-mir-16-1 Prostatic Neoplasms 21532615 miR-15 and miR-16 are downregulated in fibroblasts surrounding the prostate tumors of the majority of 23 patients analyzed. 4858 hsa-mir-16-2 Prostatic Neoplasms 21532615 miR-15 and miR-16 are downregulated in fibroblasts surrounding the prostate tumors of the majority of 23 patients analyzed. 4859 hsa-mir-15a Prostatic Neoplasms 21532615 miR-15 and miR-16 are downregulated in fibroblasts surrounding the prostate tumors of the majority of 23 patients analyzed. 4860 hsa-mir-15b Prostatic Neoplasms 21532615 miR-15 and miR-16 are downregulated in fibroblasts surrounding the prostate tumors of the majority of 23 patients analyzed. 4861 hsa-mir-101-1 Carcinoma, Squamous Cell 21532618 The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma. 4862 hsa-mir-101-2 Carcinoma, Squamous Cell 21532618 The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma. 4863 hsa-mir-215 Colorectal Neoplasms 21532750 miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors. 4864 hsa-mir-137 Colorectal Neoplasms 21532750 miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors. 4865 hsa-mir-708 Colorectal Neoplasms 21532750 miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors. 4866 hsa-mir-31 Colorectal Neoplasms 21532750 miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors. 4867 hsa-mir-135b Colorectal Neoplasms 21532750 miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors. 4868 hsa-mir-133a-1 Colorectal Neoplasms 21532750 miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors. 4869 hsa-mir-133a-2 Colorectal Neoplasms 21532750 miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors. 4870 hsa-mir-218-1 Colorectal Neoplasms 21532750 miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors. 4871 hsa-mir-218-2 Colorectal Neoplasms 21532750 miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors. 4872 hsa-let-7f-1 Stomach Neoplasms 21533124 MicroRNA Let-7f Inhibits Tumor Invasion and Metastasis by Targeting MYH9 in Human Gastric Cancer. 4873 hsa-let-7f-2 Stomach Neoplasms 21533124 MicroRNA Let-7f Inhibits Tumor Invasion and Metastasis by Targeting MYH9 in Human Gastric Cancer. 4874 hsa-mir-375 Esophageal Neoplasms 21533613 Epigenetic Silencing of MicroRNA-375 Regulates PDK1 Expression in Esophageal Cancer 4875 hsa-mir-375 Esophageal Neoplasms 21533613 Epigenetic Silencing of MicroRNA-375 Regulates PDK1 Expression in Esophageal Cancer. 4876 hsa-mir-146b Thyroid Neoplasms 21537871 miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC. 4877 hsa-mir-221 Thyroid Neoplasms 21537871 miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC. 4878 hsa-mir-222 Thyroid Neoplasms 21537871 miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC. 4879 hsa-mir-155 Thyroid Neoplasms 21537871 miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC. 4880 hsa-mir-31 Thyroid Neoplasms 21537871 miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC. 4881 hsa-mir-1-1 Thyroid Neoplasms 21537871 miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC. 4882 hsa-mir-1-2 Thyroid Neoplasms 21537871 miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC. 4883 hsa-mir-34b Thyroid Neoplasms 21537871 miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC. 4884 hsa-mir-133b Thyroid Neoplasms 21537871 miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC. 4885 hsa-mir-138-1 Thyroid Neoplasms 21537871 miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC. 4886 hsa-mir-138-2 Thyroid Neoplasms 21537871 miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC. 4887 hsa-mir-221 Colorectal Neoplasms 21538272 MicroRNA-221 controls CDKN1C/P57 expression in human colorectal carcinoma 4888 hsa-mir-126 Lupus Erythematosus, Systemic 21538319 MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1. 4889 hsa-mir-9-1 Wounds and Injuries 21538484 Upregulated in in serum 4890 hsa-mir-9-2 Wounds and Injuries 21538484 Upregulated in in serum 4891 hsa-mir-9-3 Wounds and Injuries 21538484 Upregulated in in serum 4892 hsa-mir-16-1 Prostatic Neoplasms 21539977 We observed correlations with clinical-pathologic parameters: miR-16, miR-195, and miR-26a were significantly correlated with surgical margin positivity; miR-195 and miR-let7i were significantly correlated with the Gleason score. 4893 hsa-mir-16-2 Prostatic Neoplasms 21539977 We observed correlations with clinical-pathologic parameters: miR-16, miR-195, and miR-26a were significantly correlated with surgical margin positivity; miR-195 and miR-let7i were significantly correlated with the Gleason score. 4894 hsa-mir-195 Prostatic Neoplasms 21539977 We observed correlations with clinical-pathologic parameters: miR-16, miR-195, and miR-26a were significantly correlated with surgical margin positivity; miR-195 and miR-let7i were significantly correlated with the Gleason score. 4895 hsa-mir-26a-1 Prostatic Neoplasms 21539977 We observed correlations with clinical-pathologic parameters: miR-16, miR-195, and miR-26a were significantly correlated with surgical margin positivity; miR-195 and miR-let7i were significantly correlated with the Gleason score. 4896 hsa-mir-26a-2 Prostatic Neoplasms 21539977 We observed correlations with clinical-pathologic parameters: miR-16, miR-195, and miR-26a were significantly correlated with surgical margin positivity; miR-195 and miR-let7i were significantly correlated with the Gleason score. 4897 hsa-mir-379 Carcinoma, Hepatocellular 21540293 Down-regulation of ABCC2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379. 4898 hsa-mir-155 Nasopharyngeal Neoplasms 21541331 Upregulation of MiR-155 in Nasopharyngeal Carcinoma is Partly Driven by LMP1 and LMP2A and Downregulates a Negative Prognostic Marker JMJD1A. 4899 hsa-mir-142 Melanoma 21543894 miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04). 4900 hsa-mir-486 Melanoma 21543894 miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04). 4901 hsa-mir-214 Melanoma 21543894 miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04). 4902 hsa-mir-362 Melanoma 21543894 miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04). 4903 hsa-mir-650 Melanoma 21543894 miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04). 4904 hsa-mir-31 Melanoma 21543894 miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04). 4905 hsa-mir-137 Melanoma 21543894 miR-137 under expression was significantly associated with melanomas with the KRAS-variant. 4906 hsa-mir-218-1 Melanoma 21543894 miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04). 4907 hsa-mir-218-2 Melanoma 21543894 miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04). 4908 hsa-mir-24-1 Lymphoma 21544199 miR-124-1 is epigenetically inactivated in Haematological Malignancies. 4909 hsa-mir-24-1 Multiple Myeloma 21544199 miR-124-1 is epigenetically inactivated in Haematological Malignancies. 4910 hsa-mir-24-1 Leukemia, Myeloid, Acute 21544199 miR-124-1 is epigenetically inactivated in Haematological Malignancies. 4911 hsa-mir-146b Carcinoma, Non-Small-Cell Lung 21544802 The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased. 4912 hsa-mir-221 Carcinoma, Non-Small-Cell Lung 21544802 The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased. 4913 hsa-let-7a-1 Carcinoma, Non-Small-Cell Lung 21544802 The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased. 4914 hsa-let-7a-2 Carcinoma, Non-Small-Cell Lung 21544802 The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased. 4915 hsa-let-7a-3 Carcinoma, Non-Small-Cell Lung 21544802 The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased. 4916 hsa-mir-155 Carcinoma, Non-Small-Cell Lung 21544802 The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased. 4917 hsa-mir-17 Carcinoma, Non-Small-Cell Lung 21544802 The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased. 4918 hsa-mir-27a Carcinoma, Non-Small-Cell Lung 21544802 The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased. 4919 hsa-mir-106a Carcinoma, Non-Small-Cell Lung 21544802 The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased. 4920 hsa-mir-29c Carcinoma, Non-Small-Cell Lung 21544802 The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased. 4921 hsa-let-7b Carcinoma, Non-Small-Cell Lung 21544802 Reduced plasma expression of let-7b was modestly associated with worse cancer-specific mortality in all patients and reduced serum expression of miR-223 was modestly associated with cancer-specific mortality in stage IA/B patients. 4922 hsa-mir-223 Carcinoma, Non-Small-Cell Lung 21544802 Reduced plasma expression of let-7b was modestly associated with worse cancer-specific mortality in all patients and reduced serum expression of miR-223 was modestly associated with cancer-specific mortality in stage IA/B patients. 4923 hsa-mir-21 Colorectal Neoplasms 21546206 This study demonstrates the inverse relationship between miR-21 and PDCD4, thus suggesting that miR-21 post-transcriptionally modulates PDCD4 via mRNA degradation. Pharmacological manipulation of the miR-21/PDCD4 axis could represent a novel therapeutic strategy in the treatment of colorectal cancer. 4924 hsa-mir-34a Esophageal Neoplasms 21547903 The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01). 4925 hsa-mir-34b Esophageal Neoplasms 21547903 The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01). 4926 hsa-mir-34c Esophageal Neoplasms 21547903 The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01). 4927 hsa-mir-129-2 Esophageal Neoplasms 21547903 The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01). 4928 hsa-mir-34a Carcinoma, Squamous Cell 21547903 The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01). 4929 hsa-mir-34b Carcinoma, Squamous Cell 21547903 The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01). 4930 hsa-mir-34c Carcinoma, Squamous Cell 21547903 The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01). 4931 hsa-mir-129-2 Carcinoma, Squamous Cell 21547903 The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01). 4932 hsa-mir-590 Alzheimer Disease 21548758 Decreased relative expression levels of hsa-miR-590-3p in blood cells was observed in patients with AD versus controls. hnRNP-A1 and its transcription regulatory factor miR-590-3p are disregulated in patients with AD, and the hnRNP-A1 rs7967622 C/C genotype is likely a risk factor for FTLD in male populations. 4933 hsa-let-7d Prostatic Neoplasms 21548940 PBX3 is up-regulated in prostate cancer and post- transcriptionally regulated by androgen through Let-7d. 4934 hsa-mir-143 Urinary Bladder Neoplasms 21550168 MicroRNA-143 functions as a tumor suppressor in human bladder cancer T24 cells 4935 hsa-mir-29c Esophageal Neoplasms 21551130 miR-29c induces cell cycle arrest in Esophageal Squamous Cell Carcinoma by modulating Cyclin E expression. 4936 hsa-mir-29c Carcinoma, Squamous Cell 21551130 miR-29c induces cell cycle arrest in Esophageal Squamous Cell Carcinoma by modulating Cyclin E expression. 4937 hsa-mir-124-1 Cerebral Infarction 21551949 Plasma concentrations of miR-124 were significantly elevated at 6 h, and remained elevated at 48 h after middle cerebral artery occlusion introduction. 4938 hsa-mir-124-2 Cerebral Infarction 21551949 Plasma concentrations of miR-124 were significantly elevated at 6 h, and remained elevated at 48 h after middle cerebral artery occlusion introduction. 4939 hsa-mir-124-3 Cerebral Infarction 21551949 Plasma concentrations of miR-124 were significantly elevated at 6 h, and remained elevated at 48 h after middle cerebral artery occlusion introduction. 4940 hsa-mir-135a-1 Carcinoma, Non-Small-Cell Lung 21552288 miR-135a contributes to paclitaxel resistance in tumor cells both in vitro and in vivo. 4941 hsa-mir-135a-2 Carcinoma, Non-Small-Cell Lung 21552288 miR-135a contributes to paclitaxel resistance in tumor cells both in vitro and in vivo. 4942 hsa-mir-148a Stomach Neoplasms 21552422 miR-148a Promoted Cell Proliferation by Targeting p27 in Gastric Cancer Cells. 4943 hsa-mir-200c Breast Neoplasms 21553120 Suppression of miR-200c, miR-203, and miR-205 and increases in miR-222 and miR-221 are involved in the inducement of EMT and repression of the estrogen receptor. 4944 hsa-mir-203 Breast Neoplasms 21553120 Suppression of miR-200c, miR-203, and miR-205 and increases in miR-222 and miR-221 are involved in the inducement of EMT and repression of the estrogen receptor. 4945 hsa-mir-205 Breast Neoplasms 21553120 Suppression of miR-200c, miR-203, and miR-205 and increases in miR-222 and miR-221 are involved in the inducement of EMT and repression of the estrogen receptor. 4946 hsa-mir-222 Breast Neoplasms 21553120 Suppression of miR-200c, miR-203, and miR-205 and increases in miR-222 and miR-221 are involved in the inducement of EMT and repression of the estrogen receptor. 4947 hsa-mir-221 Breast Neoplasms 21553120 Suppression of miR-200c, miR-203, and miR-205 and increases in miR-222 and miR-221 are involved in the inducement of EMT and repression of the estrogen receptor. 4948 hsa-mir-7-1 Thyroid Neoplasms 21553140 miR-7 and miR-126 could be candidate diagnostic microRNAs for thyroid histologic subtypes. 4949 hsa-mir-7-2 Thyroid Neoplasms 21553140 miR-7 and miR-126 could be candidate diagnostic microRNAs for thyroid histologic subtypes. 4950 hsa-mir-7-3 Thyroid Neoplasms 21553140 miR-7 and miR-126 could be candidate diagnostic microRNAs for thyroid histologic subtypes. 4951 hsa-mir-126 Thyroid Neoplasms 21553140 miR-7 and miR-126 could be candidate diagnostic microRNAs for thyroid histologic subtypes. 4952 hsa-mir-125b-1 Prostatic Neoplasms 21556765 rs1434536 in the 3'UTR of BMPR1B gene affects the binding ability of miR-125b to BMPR1B mRNA and contributes to the genetic hspredisposition to localized prostate cancer and patients aged >70years. 4953 hsa-mir-125b-2 Prostatic Neoplasms 21556765 rs1434536 in the 3'UTR of BMPR1B gene affects the binding ability of miR-125b to BMPR1B mRNA and contributes to the genetic hspredisposition to localized prostate cancer and patients aged >70years. 4954 hsa-mir-143 Colitis, Ulcerative 21557394 miR-143 and miR-145 are downregulated in ulcerative colitis 4955 hsa-mir-145 Colitis, Ulcerative 21557394 miR-143 and miR-145 are downregulated in ulcerative colitis 4956 hsa-mir-199b Carcinoma, Hepatocellular 21557766 hsa-miR-199b-5p: Patients with lower levels of miR-199b expression had poorer overall survival and progression-free survival rates, whereas patients with higher levels of miR-199b expression had better survival. 4957 hsa-mir-637 Hypertension 21558123 A common genetic variant (rs938671) in the 3'-UTR of Vacuolar H+-ATPase ATP6V0A1 creates a micro-RNA (hsa-miR-637) motif to alter Chromogranin A (CHGA) processing and hypertension risk. 4958 hsa-mir-519a-1 Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4959 hsa-mir-519a-2 Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4960 hsa-mir-519b Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4961 hsa-mir-519c Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4962 hsa-mir-519d Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4963 hsa-mir-519e Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4964 hsa-mir-520a Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4965 hsa-mir-520b Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4966 hsa-mir-520e Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4967 hsa-mir-520d Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4968 hsa-mir-520f Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4969 hsa-mir-520g Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4970 hsa-mir-520h Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. 4971 hsa-mir-34b Parkinson Disease 21558425 This miRNA was downregulated in brain areas with variable neuropathological affectation at clinical (motor) stages (Braak stages 4 and 5) of the disease,including the amygdala, frontal cortex, substantia nigra and cerebellum. This miRNA modulate mitochondrial function. 4972 hsa-mir-34c Parkinson Disease 21558425 This miRNA was downregulated in brain areas with variable neuropathological affectation at clinical (motor) stages (Braak stages 4 and 5) of the disease,including the amygdala, frontal cortex, substantia nigra and cerebellum. This miRNA modulate mitochondrial function. 4973 hsa-mir-100 Head and Neck Neoplasms 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4974 hsa-mir-130a Head and Neck Neoplasms 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4975 hsa-mir-197 Head and Neck Neoplasms 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4976 hsa-mir-181d Head and Neck Neoplasms 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4977 hsa-mir-195 Head and Neck Neoplasms 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4978 hsa-mir-100 Carcinoma, Squamous Cell 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4979 hsa-mir-130a Carcinoma, Squamous Cell 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4980 hsa-mir-197 Carcinoma, Squamous Cell 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4981 hsa-mir-181d Carcinoma, Squamous Cell 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4982 hsa-mir-195 Carcinoma, Squamous Cell 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4983 hsa-mir-101-1 Head and Neck Neoplasms 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4984 hsa-mir-101-2 Head and Neck Neoplasms 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4985 hsa-mir-181b-1 Head and Neck Neoplasms 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4986 hsa-mir-181b-2 Head and Neck Neoplasms 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4987 hsa-mir-101-1 Carcinoma, Squamous Cell 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4988 hsa-mir-101-2 Carcinoma, Squamous Cell 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4989 hsa-mir-181b-1 Carcinoma, Squamous Cell 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4990 hsa-mir-181b-2 Carcinoma, Squamous Cell 21560177 Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01). 4991 hsa-mir-342 Glioblastoma 21561454 miR-342-3p: downregulated in the peripheral blood of glioblastoma patients. 4992 hsa-mir-128-1 Glioblastoma 21561454 upregulated in the peripheral blood of glioblastoma patients. 4993 hsa-mir-128-2 Glioblastoma 21561454 upregulated in the peripheral blood of glioblastoma patients. 4994 hsa-mir-10b Stomach Neoplasms 21562367 miR-10b methylation may be a useful molecular biomarker for assessing the risk of gastric cancer development, and modulation of miR-10b may represent a therapeutic approach for treating gastric cancer. 4995 hsa-mir-9-1 Colorectal Neoplasms 21562850 MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility. 4996 hsa-mir-9-2 Colorectal Neoplasms 21562850 MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility. 4997 hsa-mir-9-3 Colorectal Neoplasms 21562850 MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility. 4998 hsa-mir-196a-2 Pulmonary Disease, Chronic Obstructive 21565178 The TT genotype and T allele of miR-196a2 rs11614913 were significantly associated with a decreased risk for COPD (Chronic obstructive pulmonary disease), compared with the CC genotype and C allele. Similarly, the GG genotype and G allele of miR-499 rs3746444 were associated with a decreased risk for COPD, compared with the AA genotype and A allele. 4999 hsa-mir-499a Pulmonary Disease, Chronic Obstructive 21565178 The TT genotype and T allele of miR-196a2 rs11614913 were significantly associated with a decreased risk for COPD (Chronic obstructive pulmonary disease), compared with the CC genotype and C allele. Similarly, the GG genotype and G allele of miR-499 rs3746444 were associated with a decreased risk for COPD, compared with the AA genotype and A allele. 5000 hsa-mir-196a-2 Colorectal Neoplasms 21565628 A Functional Variant in MicroRNA-196a2 (rs11614913 SNP) Is Associated with Susceptibility of Colorectal Cancer in a Chinese Population. 5001 hsa-mir-342 Colorectal Neoplasms 21565830 MicroRNA-342 Inhibits Colorectal Cancer Cell Proliferation and Invasion by Directly Targeting DNA Methyltransferase 1. 5002 hsa-mir-34a Leukemia, Lymphocytic, Chronic, B-Cell 21565980 Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network. 5003 hsa-mir-21 Rectal Neoplasms 21567082 Altered levels of the onco-microRNA 21 and the tumor-supressor microRNAs 143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapy. 5004 hsa-mir-145 Rectal Neoplasms 21567082 Altered levels of the onco-microRNA 21 and the tumor-supressor microRNAs 143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapy. 5005 hsa-mir-143 Rectal Neoplasms 21567082 Altered levels of the onco-microRNA 21 and the tumor-supressor microRNAs 143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapy. 5006 hsa-mir-27a Stomach Neoplasms 21569481 Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells. 5007 hsa-let-7a-1 Ovarian Neoplasms 21571355 let-7a is a potential marker for selection of paclitaxel in ovarian cancer management. 5008 hsa-mir-92a-1 Neuroblastoma 21572098 MYCN-regulated miRNA-92 Inhibits Secretion of the Tumor Suppressor DICKKOPF-3 (DKK3) in Neuroblastoma. 5009 hsa-mir-92a-2 Neuroblastoma 21572098 MYCN-regulated miRNA-92 Inhibits Secretion of the Tumor Suppressor DICKKOPF-3 (DKK3) in Neuroblastoma. 5010 hsa-mir-92b Neuroblastoma 21572098 MYCN-regulated miRNA-92 Inhibits Secretion of the Tumor Suppressor DICKKOPF-3 (DKK3) in Neuroblastoma. 5011 hsa-mir-29a Carcinoma, Hepatocellular 21573166 Upregulated MicroRNA-29a by Hepatitis B Virus X Protein Enhances Hepatoma Cell Migration by Targeting PTEN in Cell Culture Model. 5012 hsa-mir-185 Colorectal Neoplasms 21573504 High expression of miR-185 and low expression of miR-133b were correlated with poor survival (p=0.001 and 0.028, respectively) and metastasis (p=0.007 and 0.036, respectively) in colorectal cancer. 5013 hsa-mir-133b Colorectal Neoplasms 21573504 High expression of miR-185 and low expression of miR-133b were correlated with poor survival (p=0.001 and 0.028, respectively) and metastasis (p=0.007 and 0.036, respectively) in colorectal cancer. 5014 hsa-mir-34a Carcinoma, Non-Small-Cell Lung 21575235 miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. 5015 hsa-mir-15a Carcinoma, Non-Small-Cell Lung 21575235 miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. 5016 hsa-mir-16-1 Carcinoma, Non-Small-Cell Lung 21575235 miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. 5017 hsa-mir-16-2 Carcinoma, Non-Small-Cell Lung 21575235 miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. 5018 hsa-mir-335 Astrocytoma 21592405 Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells. 5019 hsa-mir-7-1 Neoplasms 21592959 USP18 regulates EGF receptor expression and cancer cell survival via microrna-7. 5020 hsa-mir-7-2 Neoplasms 21592959 USP18 regulates EGF receptor expression and cancer cell survival via microrna-7. 5021 hsa-mir-7-3 Neoplasms 21592959 USP18 regulates EGF receptor expression and cancer cell survival via microrna-7. 5022 hsa-mir-375 Prostatic Neoplasms 21593139 miRNA-375 Downregulated Sec23A protein in prostate carcinoma. 5023 hsa-mir-22 Colorectal Neoplasms 21594648 Overexpression of miR-22 reverses paclitaxel-induced chemoresistance through activation of PTEN signaling in p53-mutated colon cancer cells. 5024 hsa-mir-1302-1 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro. 5025 hsa-mir-1302-2 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro. 5026 hsa-mir-1302-3 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro. 5027 hsa-mir-1302-4 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro. 5028 hsa-mir-1302-5 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro. 5029 hsa-mir-1302-6 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro. 5030 hsa-mir-1302-7 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro. 5031 hsa-mir-1302-8 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro. 5032 hsa-mir-21 Lupus Erythematosus, Systemic 21602271 miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression.Upregulated miR-21 affects PDCD4 expression and regulates aberrant T cell responses in human SLE. 5033 hsa-let-7a-1 Myelodysplastic Syndromes 21602527 Circulating microRNAs let-7a and miR-16 predict progression-free survival and overall survival in patients with myelodysplastic syndrome. 5034 hsa-let-7a-2 Myelodysplastic Syndromes 21602527 Circulating microRNAs let-7a and miR-16 predict progression-free survival and overall survival in patients with myelodysplastic syndrome. 5035 hsa-let-7a-3 Myelodysplastic Syndromes 21602527 Circulating microRNAs let-7a and miR-16 predict progression-free survival and overall survival in patients with myelodysplastic syndrome. 5036 hsa-mir-16-1 Myelodysplastic Syndromes 21602527 Circulating microRNAs let-7a and miR-16 predict progression-free survival and overall survival in patients with myelodysplastic syndrome. 5037 hsa-mir-16-2 Myelodysplastic Syndromes 21602527 Circulating microRNAs let-7a and miR-16 predict progression-free survival and overall survival in patients with myelodysplastic syndrome. 5038 hsa-mir-196a-2 Hepatitis C 21604580 SNP rs11614913 on miR196a-2 gene is associated with the antiviral therapy efficacy of hepatitis C patients.The TT genotype or T alleles be associated with the SVR while the CC genotype or C allele could be related to the NVR or recurrence. 5039 hsa-mir-126 Asthma 21605405 upregulated compared with normal control 5040 hsa-mir-29a Hepatitis C 21606534 Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture. 5041 hsa-mir-29c Hepatitis C 21606534 Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture. 5042 hsa-mir-29b-1 Hepatitis C 21606534 Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture. 5043 hsa-mir-29b-2 Hepatitis C 21606534 Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture. 5044 hsa-mir-122 Hepatitis B, Chronic 21606975 The serum level of miR-122 strongly correlates with serum ALT activity and with necroinflammatory activity in patients with CHC and elevated ALT levels, but not with fibrosis stage and functional capacity of the liver 5045 hsa-mir-372 Hepatitis B 21608007 MicroRNAs-372/373 promote the expression of hepatitis B Virus through the targeting of nuclear factor I/B. 5046 hsa-mir-373 Hepatitis B 21608007 MicroRNAs-372/373 promote the expression of hepatitis B Virus through the targeting of nuclear factor I/B. 5047 hsa-mir-146a Lymphoma 21610143 MicroRNA-146a downregulates NF{kappa}B activity via targeting TRAF6, and functions as a tumor suppressor having strong prognostic implications in NK/T cell lymphoma. 5048 hsa-mir-26a-1 Carcinoma, Hepatocellular 21610700 Tumor-specific Expression of MicroRNA-26a Suppresses Human Hepatocellular Carcinoma Growth via Cyclin-dependent and -independent Pathways. 5049 hsa-mir-26a-2 Carcinoma, Hepatocellular 21610700 Tumor-specific Expression of MicroRNA-26a Suppresses Human Hepatocellular Carcinoma Growth via Cyclin-dependent and -independent Pathways. 5050 hsa-mir-34b Colorectal Neoplasms 21610744 Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer. 5051 hsa-mir-34c Colorectal Neoplasms 21610744 Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer. 5052 hsa-mir-346 Arthritis, Rheumatoid 21611196 miR-346 Controls Release of TNF-a Protein and Stability of Its mRNA in Rheumatoid Arthritis via Tristetraprolin Stabilization. 5053 hsa-mir-21 Diabetes Mellitus 21613227 microRNA-21 orchestrates high glucose-induced signals to TORC1 for renal cell pathology in diabetes. 5054 hsa-let-7a-1 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 5055 hsa-let-7a-2 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 5056 hsa-let-7a-3 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 5057 hsa-let-7b Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 5058 hsa-let-7c Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 5059 hsa-let-7d Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 5060 hsa-let-7e Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 5061 hsa-let-7f-1 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 5062 hsa-let-7f-2 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 5063 hsa-let-7g Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 5064 hsa-let-7i Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 5065 hsa-mir-196a-2 Carcinoma, Non-Small-Cell Lung 21617338 MicroRNA196a2 rs11614913 Genotypes are associated with the Risk of Non-Small Cell Lung Cancer in Korean Population. 5066 hsa-mir-21 Glioblastoma 21618027 A miR-21 inhibitor enhances apoptosis and reduces G(2)-M accumulation induced by ionizing radiation in human glioblastoma U251 cells. 5067 hsa-mir-335 Breast Neoplasms 21618216 Breast miR-335 regulates the known BRCA1 activators ERα, IGF1R, SP1 and the repressor ID4, including a feedback regulation of miR-335 expression by estrogens. Overexpression of miR-335 resulted in an upregulation of BRCA1 mRNA expression.miR-335 affects different targets in the upstream BRCA1-regulatory cascade with impact on key cellular functions such as proliferation and apoptosis. 5068 hsa-mir-195 Myocytes, Cardiac 21622680 MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1. 5069 hsa-mir-29a Carcinoma, Hepatocellular 21625215 microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer. 5070 hsa-mir-29b-1 Carcinoma, Hepatocellular 21625215 microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer. 5071 hsa-mir-29b-2 Carcinoma, Hepatocellular 21625215 microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer. 5072 hsa-mir-29c Carcinoma, Hepatocellular 21625215 microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer. 5073 hsa-mir-21 Carcinoma, Non-Small-Cell Lung 21627863 Plasma miR-21 was significantly higher in NSCLC patients than in age- and sex-matched controls (P < 0.001). miR-21 was related to TNM stage (P < 0.001), but not related to age, sex, smoking status, histological classification, lymph node status, and metastasis (all P > 0.05). 5074 hsa-mir-223 Stomach Neoplasms 21628394 miRNA-223 Promotes Gastric Cancer Invasion and Metastasis by Targeting Tumor Suppressor EPB41L3. 5075 hsa-mir-15a Carcinoma, Hepatocellular 21629246 Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro. 5076 hsa-mir-16-1 Carcinoma, Hepatocellular 21629246 Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro. 5077 hsa-mir-16-2 Carcinoma, Hepatocellular 21629246 Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro. 5078 hsa-mir-22 Colorectal Neoplasms 21629773 MicroRNA-22 regulates hypoxia signaling in colon cancer cells. 5079 hsa-mir-146a Stomach Neoplasms 21632853 miR-146a levels in cancer tissues were significantly lower than those in the corresponding noncancerous tissue. Lower levels of miR-146a were associated with lymph node metastasis and venous invasion. Moreover, a lower level of miR-146a was an independent prognostic factor for overall survival.Ectopic expression of miR-146a inhibited migration and invasion and downregulated EGFR and IRAK1 expression in gastric cancer cells. In addition, G/C SNP within the pre-miR-146a seed sequence significantly reduced miR-146a levels in the GG genotype compared with the CC genotype. 5080 hsa-mir-30a Carcinoma, Non-Small-Cell Lung 21633953 MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer. 5081 hsa-mir-100 Breast Neoplasms 21634028 micro-RNA 100 Regulated beta-tubulin isotypes in MCF7 breast cancer cells. 5082 hsa-mir-100 Uterine Cervical Neoplasms 21636267 Reduced expression and had carcinogenic effect through targeting PLK1 protein. 5083 hsa-mir-21 Glioblastoma 21636706 Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo. 5084 hsa-mir-21 Inflammation 21636785 MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation. 5085 hsa-mir-181b-1 Leukemia, Lymphocytic, Chronic, B-Cell 21636858 MiR-181b is a biomarker of disease progression in chronic lymphocytic leukemia 5086 hsa-mir-181b-2 Leukemia, Lymphocytic, Chronic, B-Cell 21636858 MiR-181b is a biomarker of disease progression in chronic lymphocytic leukemia 5087 hsa-mir-1246 Down Syndrome 21637297 p53 downregulates Down syndrome-associated DYRK1A through miR-1246. 5088 hsa-mir-181a-2 Head and Neck Neoplasms 21637912 hsa-miR-181a-2* was upregulated compared with normal tissue. 5089 hsa-mir-181a-1 Head and Neck Neoplasms 21637912 hsa-miR-181a was upregulated compared with normal tissue. 5090 hsa-mir-181b-1 Head and Neck Neoplasms 21637912 hsa-miR-181b was upregulated compared with normal tissue. 5091 hsa-mir-181b-2 Head and Neck Neoplasms 21637912 hsa-miR-181b was upregulated compared with normal tissue. 5092 hsa-mir-744 Head and Neck Neoplasms 21637912 hsa-miR-744 was upregulated compared with normal tissue. 5093 hsa-mir-1271 Head and Neck Neoplasms 21637912 hsa-miR-1271 was upregulated compared with normal tissue. 5094 hsa-mir-221 Head and Neck Neoplasms 21637912 hsa-miR-221* was upregulated compared with normal tissue. 5095 hsa-mir-141 Head and Neck Neoplasms 21637912 hsa-miR-141 was downregulated compared with normal tissue. 5096 hsa-mir-95 Head and Neck Neoplasms 21637912 hsa-miR-95 was downregulated compared with normal tissue. 5097 hsa-mir-101-1 Head and Neck Neoplasms 21637912 hsa-miR-101 was downregulated compared with normal tissue. 5098 hsa-mir-101-2 Head and Neck Neoplasms 21637912 hsa-miR-101 was downregulated compared with normal tissue. 5099 hsa-mir-130a Leukemia, Myeloid 21638198 MicroRNAs 130a/b are regulated by BCR-ABL and downregulate expression of CCN3 in CML (Chronic Myeloid Leukaemia). 5100 hsa-mir-130b Leukemia, Myeloid 21638198 MicroRNAs 130a/b are regulated by BCR-ABL and downregulate expression of CCN3 in CML (Chronic Myeloid Leukaemia). 5101 hsa-mir-1-1 Myocardial Infarction 21642241 Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage. 5102 hsa-mir-1-2 Myocardial Infarction 21642241 Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage. 5103 hsa-mir-133a-1 Myocardial Infarction 21642241 Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage. 5104 hsa-mir-133a-2 Myocardial Infarction 21642241 Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage. 5105 hsa-mir-100 Leukemia, Myeloid, Acute 21643017 MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia. 5106 hsa-mir-372 Uterine Cervical Neoplasms 21646351 MicroRNA-372 Is Down-regulated and Targets Cyclin-dependent Kinase 2 (CDK2) and Cyclin A1 in Human Cervical Cancer, Which May Contribute to Tumorigenesis. 5107 hsa-mir-21 Wounds and Injuries 21647251 miR-21 promotes keratinocyte migration and re-epithelialization during wound healing. 5108 hsa-mir-143 Prostatic Neoplasms 21647377 miRs-143 and -145 are associated with bone metastasis of prostate cancer and involved in the regulation of EMT. 5109 hsa-mir-145 Prostatic Neoplasms 21647377 miRs-143 and -145 are associated with bone metastasis of prostate cancer and involved in the regulation of EMT. 5110 hsa-mir-720 Myelodysplastic Syndromes 21649547 up-regulation 5111 hsa-mir-21 Myelodysplastic Syndromes 21649547 up-regulation 5112 hsa-mir-671 Myelodysplastic Syndromes 21649547 miR-671-5p: down-regulation 5113 hsa-mir-10b Pancreatic Neoplasms 21652542 microRNA-10b Expression Correlates with Response to Neoadjuvant Therapy and Survival in Pancreatic Ductal Adenocarcinoma. 5114 hsa-mir-122 Hepatitis C 21653556 miR-122 activates hepatitis C virus translation by a specialized mechanism requiring particular RNA components. 5115 hsa-mir-122 Carcinoma, Hepatocellular 21654638 MicroRNA122 is a key regulator of alpha-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma. 5116 hsa-mir-103a-1 Diabetes Mellitus, Type 2 21654750 MicroRNAs 103 and 107 regulate insulin sensitivity. 5117 hsa-mir-103a-2 Diabetes Mellitus, Type 2 21654750 MicroRNAs 103 and 107 regulate insulin sensitivity. 5118 hsa-mir-492 Psoriasis 21655935 The rs8259 T allele was associated with significantly decreased psoriasis susceptibility (OR?=?0.758, 95% CI 0.638-0.901, p?=?0.002) compared to A allele. the rs8259 polymorphism was located in a seed region for miR-492 binding. 5119 hsa-mir-222 Lung Neoplasms 21656127 High-mobility group A1 proteins enhance the expression of the oncogenic miR-222 in lung cancer cells. 5120 hsa-mir-106a Glioblastoma 21656380 MiR-106a inhibits glioma cell growth by targeting E2F1 independent of p53 status. 5121 hsa-mir-31 Carcinoma, Squamous Cell 21658006 miR-31 was up-regulated in 77.8% of the ESCC tissues. Serum miR-31 levels in ESCC patients were significantly higher than in normal controls (P<0.001). 5122 hsa-mir-198 Carcinoma, Hepatocellular 21658389 miR-198 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the HGF/c-MET pathway. 5123 hsa-mir-17 Multiple Myeloma 21664042 miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. 5124 hsa-mir-18a Multiple Myeloma 21664042 miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. 5125 hsa-mir-19a Multiple Myeloma 21664042 miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. 5126 hsa-mir-20a Multiple Myeloma 21664042 miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. 5127 hsa-mir-19b-1 Multiple Myeloma 21664042 miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. 5128 hsa-mir-92a-1 Multiple Myeloma 21664042 miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. 5129 hsa-mir-132 Pancreatic Neoplasms 21665894 Downregulation of miR-132 by promoter methylation contributes to pancreatic cancer development. 5130 hsa-mir-345 Colorectal Neoplasms 21665895 MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer. 5131 hsa-mir-199a-1 Osteosarcoma 21666078 MicroRNA-199a-3p Is Downregulated in Human Osteosarcoma and Regulates Cell Proliferation and Migration. 5132 hsa-mir-199a-2 Osteosarcoma 21666078 MicroRNA-199a-3p Is Downregulated in Human Osteosarcoma and Regulates Cell Proliferation and Migration. 5133 hsa-mir-451a Breast Neoplasms 21666713 Tamoxifen downregulation of miR-451 increases 14-3-3 and promotes breast cancer cell survival and endocrine resistance. 5134 hsa-mir-370 Stomach Neoplasms 21666718 Overexpression of miR-370 and downregulation of its novel target TGFbeta-RII contribute to the progression of gastric carcinoma. 5135 hsa-mir-1-1 Myocardium 21671035 ES cells overexpressing microRNA-1 attenuate apoptosis in the injured myocardium. 5136 hsa-mir-1-2 Myocardium 21671035 ES cells overexpressing microRNA-1 attenuate apoptosis in the injured myocardium. 5137 hsa-mir-338 Carcinoma, Hepatocellular 21671467 miR-338-3p suppresses invasion of liver cancer cell by targeting smoothened. 5138 hsa-mir-192 Carcinoma, Hepatocellular 21672525 MiR-192 inhibits nucleotide excision repair by targeting ERCC3 and ERCC4 in HepG2.2.15 cells. 5139 hsa-mir-124-1 Carcinoma, Hepatocellular 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. 5140 hsa-mir-124-2 Carcinoma, Hepatocellular 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. 5141 hsa-mir-124-3 Carcinoma, Hepatocellular 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. 5142 hsa-mir-34b Mesothelioma 21673066 Epigenetic Silencing of MicroRNA-34b/c Plays an Important Role in the Pathogenesis of Malignant Pleural Mesothelioma. 5143 hsa-mir-34c Mesothelioma 21673066 Epigenetic Silencing of MicroRNA-34b/c Plays an Important Role in the Pathogenesis of Malignant Pleural Mesothelioma. 5144 hsa-mir-221 Breast Neoplasms 21673316 TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer. 5145 hsa-mir-21 Carcinoma, Squamous Cell 21673684 the plasma level of miR-21 was significantly higher (P=0.0218) and that of miR-375 (P=0.0052) was significantly lower in ESCC patients than controls. (2) The high plasma miR-21 levels reflected tumour levels in all cases (100%). The plasma level of miR-21 was significantly reduced in postoperative samples (P=0.0058). (3) On validation analysis, the plasma level of miR-21 tended to be higher in ESCC patients (P=0.0649), while that of miR-375 was significantly lower (P<0.0001) and the miR-21/miR-375 ratio was significantly higher (P<0.0001) in ESCC patients than in controls. The value of the area under the receiver-operating characteristic curve (AUC) was 0.816 for the miR-21/miR-375 ratio assay. Patients with a high plasma level of miR-21 tended to have greater vascular invasion (P=0.1554) and to show a high correlation with recurrence (P=0.0164). 5146 hsa-mir-375 Carcinoma, Squamous Cell 21673684 the plasma level of miR-21 was significantly higher (P=0.0218) and that of miR-375 (P=0.0052) was significantly lower in ESCC patients than controls. (2) The high plasma miR-21 levels reflected tumour levels in all cases (100%). The plasma level of miR-21 was significantly reduced in postoperative samples (P=0.0058). (3) On validation analysis, the plasma level of miR-21 tended to be higher in ESCC patients (P=0.0649), while that of miR-375 was significantly lower (P<0.0001) and the miR-21/miR-375 ratio was significantly higher (P<0.0001) in ESCC patients than in controls. The value of the area under the receiver-operating characteristic curve (AUC) was 0.816 for the miR-21/miR-375 ratio assay. Patients with a high plasma level of miR-21 tended to have greater vascular invasion (P=0.1554) and to show a high correlation with recurrence (P=0.0164). 5147 hsa-mir-1827 Carcinoma, Small Cell 21676885 Genetic Variation in an miRNA-1827 Binding Site in MYCL1 Alters Susceptibility to Small-Cell Lung Cancer. The rs3134615T allele was associated with a significantly increased risk of SCLC, with the OR for carrying the GT or TT genotype being 2.08 (95% confidence interval, 1.39-3.21; P = 0.0004) compared with the GG genotype. 5148 hsa-mir-483 Wounds and Injuries 21676945 miR-483-3p controls proliferation in wounded epithelial cells. 5149 hsa-mir-29a Leukemia, Myeloid, Acute 21678057 miR-29a and miR-142-3p show downregulation and diagnostic implication in human acute myeloid leukemia. 5150 hsa-mir-143 Leukemia, Myeloid, Acute 21678057 miR-29a and miR-142-3p show downregulation and diagnostic implication in human acute myeloid leukemia. 5151 hsa-mir-429 Stomach Neoplasms 21684154 miR-429 Modulates the expression of c-myc in human gastric carcinoma cells. 5152 hsa-mir-9-1 Myocytes, Cardiac 21684288 MicroRNA-9 is an activation-induced regulator of PDGFR-beta expression in cardiomyocytes. 5153 hsa-mir-9-2 Myocytes, Cardiac 21684288 MicroRNA-9 is an activation-induced regulator of PDGFR-beta expression in cardiomyocytes. 5154 hsa-mir-9-3 Myocytes, Cardiac 21684288 MicroRNA-9 is an activation-induced regulator of PDGFR-beta expression in cardiomyocytes. 5155 hsa-mir-1-1 Myotonic Dystrophy 21685920 As a consequence of miR-1 loss, expression of GJA1 (connexin 43) and CACNA1C (Cav1.2), which are targets of miR-1, is increased in both DM1- and DM2-affected hearts. 5156 hsa-mir-1-2 Myotonic Dystrophy 21685920 As a consequence of miR-1 loss, expression of GJA1 (connexin 43) and CACNA1C (Cav1.2), which are targets of miR-1, is increased in both DM1- and DM2-affected hearts. 5157 hsa-mir-21 Carcinoma, Squamous Cell 21685938 Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells. 5158 hsa-mir-128-1 Alzheimer Disease 21686130 miR-128a/b levels were significantly reduced in the temporal cortex and miR-128b in the frontal cortex in AD. 5159 hsa-mir-128-2 Alzheimer Disease 21686130 miR-128a/b levels were significantly reduced in the temporal cortex and miR-128b in the frontal cortex in AD. 5160 hsa-mir-99a Psoriasis 21687694 differentially expressed. miR-99a is one of the regulators of the IGF-1R signaling pathway in keratinocytes. Activation of IGF1 signaling results in elevation of miR-99a which represses the expression of IGF-1R. 5161 hsa-mir-150 Psoriasis 21687694 differentially expressed 5162 hsa-mir-423 Psoriasis 21687694 differentially expressed 5163 hsa-mir-197 Psoriasis 21687694 differentially expressed 5164 hsa-mir-211 Melanoma 21687938 Downregulation of microRNA-211 is involved in expression of preferentially expressed antigen of melanoma in melanoma cells. 5165 hsa-mir-214 Stomach Neoplasms 21688200 Down-Regulated miRNA-214 Induces a Cell Cycle G1 Arrest in Gastric Cancer Cells by Up-Regulating the PTEN Protein. 5166 hsa-mir-155 Arthritis, Rheumatoid 21690378 miR-155 is up-regulated in synovial membrane and synovial fluid (SF) macrophages from patients with rheumatoid arthritis (RA). The increased expression of miR-155 in SF CD14(+) cells was associated with lower expression of the miR-155 target, Src homology 2-containing inositol phosphatase-1 (SHIP-1), an inhibitor of inflammation. 5167 hsa-mir-145 Colorectal Neoplasms 21690566 The authors' findings show that chemically unmodified miRNAs complexed with PEI can be used in an efficient and biocompatible strategy of miRNA replacement therapy, as illustrated by efficacious delivery of PEI/miR-145 and PEI/miR-33a complexes in colon carcinoma. 5168 hsa-mir-33a Colorectal Neoplasms 21690566 The authors' findings show that chemically unmodified miRNAs complexed with PEI can be used in an efficient and biocompatible strategy of miRNA replacement therapy, as illustrated by efficacious delivery of PEI/miR-145 and PEI/miR-33a complexes in colon carcinoma. 5169 hsa-mir-340 Breast Neoplasms 21692045 miR-340 inhibites breast cancer cell migration and invasion through targeting of oncoprotein c-Met. 5170 hsa-mir-122 Hepatitis B 21692939 Expression of the liver-specific miR-122 was significantly up-regulated in HBV-infected patients. 5171 hsa-mir-122 Liver Failure 21692939 The expression levels of miR-122 and miR-194 correlated negatively with the age of patients with CHB (chronic hepatitis B) or ACLF (acute-on-chronic liver failure). 5172 hsa-mir-194-1 Liver Failure 21692939 The expression levels of miR-122 and miR-194 correlated negatively with the age of patients with CHB (chronic hepatitis B) or ACLF (acute-on-chronic liver failure). 5173 hsa-mir-194-2 Liver Failure 21692939 The expression levels of miR-122 and miR-194 correlated negatively with the age of patients with CHB (chronic hepatitis B) or ACLF (acute-on-chronic liver failure). 5174 hsa-mir-196a-2 Carcinoma, Hepatocellular 21692953 The CC genotype of the miR-196a-2 rs11614913 polymorphism is associated with increased risk of HCC development in this Turkish population. 5175 hsa-mir-143 Liposarcoma 21693658 microRNA-143 is a tumor suppressor activity in liposarcoma 5176 hsa-mir-146a Glomerulonephritis, IGA 21694443 The expression levels of miR-146a and miR-155 in kidney biopsy and urine from patients with IgA nephropathy were elevated. 5177 hsa-mir-155 Glomerulonephritis, IGA 21694443 The expression levels of miR-146a and miR-155 in kidney biopsy and urine from patients with IgA nephropathy were elevated. 5178 hsa-mir-1-1 Colorectal Neoplasms 21694772 deregulated 5179 hsa-mir-1-2 Colorectal Neoplasms 21694772 deregulated 5180 hsa-mir-31 Colorectal Neoplasms 21694772 deregulated 5181 hsa-mir-9-1 Colorectal Neoplasms 21694772 deregulated 5182 hsa-mir-9-2 Colorectal Neoplasms 21694772 deregulated 5183 hsa-mir-9-3 Colorectal Neoplasms 21694772 deregulated 5184 hsa-mir-99a Colorectal Neoplasms 21694772 deregulated 5185 hsa-mir-137 Colorectal Neoplasms 21694772 deregulated 5186 hsa-mir-135a-1 Colorectal Neoplasms 21694772 deregulated 5187 hsa-mir-135a-2 Colorectal Neoplasms 21694772 deregulated 5188 hsa-mir-135b Colorectal Neoplasms 21694772 deregulated 5189 hsa-mir-210 Kidney Failure, Acute 21700819 Circulating miR-210 predicts survival in critically ill patients with acute kidney injury. 5190 hsa-mir-34b Carcinoma, Non-Small-Cell Lung 21702040 mir-34b and mir-126 were silenced by DNA methylation. 5191 hsa-mir-126 Carcinoma, Non-Small-Cell Lung 21702040 mir-34b and mir-126 were silenced by DNA methylation. 5192 hsa-mir-34a Urinary Bladder Neoplasms 21702042 MiR-34a chemo-sensitizes bladder cancer cells to cisplatin treatment regardless of P53-Rb pathway status. 5193 hsa-mir-148a Stomach Neoplasms 21703006 miR-148a could reduce the invasiveness, migratory and adhesive activities of gastric tumor cells. Most importantly, elevated miR-148a level in gastric cancer tissues was strongly correlated with distant metastasis, organ and peritoneal invasion and reduced survival rate. 5194 hsa-mir-125b-1 Carcinoma, Hepatocellular 21703189 microRNA-125b regulates of placenta growth factor in hepatocellular cancer 5195 hsa-mir-125b-2 Carcinoma, Hepatocellular 21703189 microRNA-125b regulates of placenta growth factor in hepatocellular cancer 5196 hsa-mir-519d Prostatic Neoplasms 21703393 miR-519d,and miR-647 could be used to separate patients with and without biochemical recurrence 5197 hsa-mir-647 Prostatic Neoplasms 21703393 miR-519d,and miR-647 could be used to separate patients with and without biochemical recurrence 5198 hsa-mir-378a Myelodysplastic Syndromes 21703983 hsa-miR-378, hsa-miR-632, and hsa-miR-636 demonstrated particularly high discrimination between MDS and normal controls. 5199 hsa-mir-632 Myelodysplastic Syndromes 21703983 hsa-miR-378, hsa-miR-632, and hsa-miR-636 demonstrated particularly high discrimination between MDS and normal controls. 5200 hsa-mir-636 Myelodysplastic Syndromes 21703983 hsa-miR-378, hsa-miR-632, and hsa-miR-636 demonstrated particularly high discrimination between MDS and normal controls. 5201 hsa-mir-143 Precursor Cell Lymphoblastic Leukemia-Lymphoma 21706045 Methylation-mediated repression of microRNA-143 enhances MLL-AF4 oncogene expression. 5202 hsa-mir-130a Carcinoma, Non-Small-Cell Lung 21706050 miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221 and 222. 5203 hsa-mir-221 Carcinoma, Non-Small-Cell Lung 21706050 miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221 and 222. 5204 hsa-mir-222 Carcinoma, Non-Small-Cell Lung 21706050 miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221 and 222. 5205 hsa-mir-155 Intervertebral Disk 21706480 Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3. 5206 hsa-mir-203 Multiple Myeloma 21707582 MIR203 is epigeneticlly silenced in multiple myeloma. 5207 hsa-mir-23a Ischemia 21709246 miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia. 5208 hsa-mir-148a Pancreatic Neoplasms 21709669 MicroRNA-148a is down-regulated in human pancreatic ductal adenocarcinomas and regulates cell survival by targeting CDC25B. 5209 hsa-mir-488 Prostatic Neoplasms 21710544 miR 488* inhibits androgen receptor expression in prostate carcinoma cells. 5210 hsa-mir-181a-1 Carcinoma, Hepatocellular 21711587 Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma. 5211 hsa-mir-181a-2 Carcinoma, Hepatocellular 21711587 Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma. 5212 hsa-mir-181b-1 Carcinoma, Hepatocellular 21711587 Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma. 5213 hsa-mir-181b-2 Carcinoma, Hepatocellular 21711587 Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma. 5214 hsa-mir-181c Carcinoma, Hepatocellular 21711587 Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma. 5215 hsa-mir-181d Carcinoma, Hepatocellular 21711587 Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma. 5216 hsa-mir-130a Carcinoma, Hepatocellular 21712254 The hepatitis B virus-associated estrogen receptor alpha (ER{alpha}) was regulated by microRNA-130a in HepG2.2.15 human hepatocellular carcinoma cells. 5217 hsa-mir-21 Multiple Myeloma 21718132 Myeloma cell adhesion to bone marrow stromal cells confers drug resistance by microRNA-21 up-regulation. 5218 hsa-mir-302a Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. 5219 hsa-mir-302b Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. 5220 hsa-mir-302c Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. 5221 hsa-mir-302d Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. 5222 hsa-mir-367 Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. 5223 hsa-mir-21 Carcinoma, Non-Small-Cell Lung 21721011 serum miR-21 expression was an independent prognostic factor for NSCLC patients. 5224 hsa-let-7b Colorectal Neoplasms 21722265 The miRNA has a role in colorectal liver metastases. 5225 hsa-mir-1275 Colorectal Neoplasms 21722265 The miRNA has a role in colorectal liver metastases. 5226 hsa-mir-143 Colorectal Neoplasms 21722265 The miRNA has a role in colorectal liver metastases. 5227 hsa-mir-145 Colorectal Neoplasms 21722265 The miRNA has a role in colorectal liver metastases. 5228 hsa-mir-638 Colorectal Neoplasms 21722265 The miRNA has a role in colorectal liver metastases. 5229 hsa-mir-19b-1 Colorectal Neoplasms 21722265 The miRNA has a role in colorectal liver metastases. 5230 hsa-mir-19b-2 Colorectal Neoplasms 21722265 The miRNA has a role in colorectal liver metastases. 5231 hsa-mir-194-1 Colorectal Neoplasms 21722265 The miRNA has a role in colorectal liver metastases. 5232 hsa-mir-194-2 Colorectal Neoplasms 21722265 The miRNA has a role in colorectal liver metastases. 5233 hsa-mir-375 Melanoma 21723283 Ectopic expression of miR-375 inhibited melanoma cell proliferation, invasion, and cell motility, and induced cell shape changes, strongly suggesting that miR-375 may have an important function in the development and progression of human melanomas. 5234 hsa-mir-141 Prostatic Neoplasms 21723797 miR-141 demonstrated high correlation with changes of the other biomarkers. 5235 hsa-mir-145 Breast Neoplasms 21723890 Ad-miR-145 suppressed cell growth and motility in both the in vitro and in vivo systems. Furthermore, a treatment combining Ad-miR-145 with 5-FU significantly showed anti-tumor effects, compared to treating alone. 5236 hsa-mir-193b Leukemia, Myeloid, Acute 21724256 MicroRNA-193b regulates c-Kit proto-oncogene and represses cell proliferation in acute myeloid leukemia. 5237 hsa-mir-187 Ovarian Neoplasms 21725366 microRNA-187 Regulates of ovarian cancer progression through targeting Disabled homolog-2. 5238 hsa-mir-200b Tongue Neoplasms 21725369 MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1. 5239 hsa-mir-15b Tongue Neoplasms 21725369 MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1. 5240 hsa-let-7d Carcinoma, Squamous Cell 21725603 Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer. 5241 hsa-mir-122 Carcinoma, Hepatocellular 21725618 miR-122 inhibits viral replication and cell proliferation in hepatitis B virus-related hepatocellular carcinoma and targets NDRG3. 5242 hsa-mir-141 Choriocarcinoma 21726338 Reduction in miR-141 is induced by leukemia inhibitory factor and inhibits proliferation in choriocarcinoma cell line JEG-3. 5243 hsa-mir-21 Carcinoma, Small Cell 21731696 The authors observed significantly lower miR-21, miR-29b, and miR-34a expression in SCLC cell lines than in NSCLC cell lines. 5244 hsa-mir-29b-1 Carcinoma, Small Cell 21731696 The authors observed significantly lower miR-21, miR-29b, and miR-34a expression in SCLC cell lines than in NSCLC cell lines. 5245 hsa-mir-29b-2 Carcinoma, Small Cell 21731696 The authors observed significantly lower miR-21, miR-29b, and miR-34a expression in SCLC cell lines than in NSCLC cell lines. 5246 hsa-mir-34a Carcinoma, Small Cell 21731696 The authors observed significantly lower miR-21, miR-29b, and miR-34a expression in SCLC cell lines than in NSCLC cell lines. 5247 hsa-mir-146a Lupus Erythematosus, Systemic 21738483 A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus. 5248 hsa-mir-210 Breast Neoplasms 21738599 MiR-210 associated with tumor proliferation, invasion and poor clinical outcome in breast cancer. 5249 hsa-mir-34a Schizophrenia 21738743 peripheral blood miR-34a was differentially expressed between cases and controls in both the learning and the testing set. 5250 hsa-mir-34a Glioblastoma 21743299 MicroRNA-34a targets notch1 and inhibits cell proliferation in glioblastoma multiforme. 5251 hsa-mir-221 Glioblastoma 21743492 miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTP mu. 5252 hsa-mir-222 Glioblastoma 21743492 miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTP mu. 5253 hsa-mir-302f Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5254 hsa-mir-302a Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5255 hsa-mir-342 Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5256 hsa-mir-425 Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5257 hsa-mir-455 Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5258 hsa-mir-486 Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5259 hsa-mir-519c Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5260 hsa-mir-617 Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5261 hsa-mir-758 Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5262 hsa-mir-766 Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5263 hsa-mir-1286 Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5264 hsa-mir-199a-1 Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5265 hsa-mir-199a-2 Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5266 hsa-mir-548d-1 Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5267 hsa-mir-548d-2 Esophageal Neoplasms 21743970 Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy. 5268 hsa-mir-146a Glioblastoma 21744077 A functional polymorphism in the pre-miR-146a gene is associated with risk and prognosis in adult glioma. An increased glioma risk was observed among rs2910164 minor allele (C) carriers (per allele OR (95%CI)?=?1.22 (1.01-1.46, p (trend)?=?0.039)). The association was stronger among older subjects carrying at least one copy of the C allele (OR (95% CI)?=?1.38 (1.04-1.83, P?=?0.026). Mortality was increased among minor allele carriers (HR(95% CI)=1.33 (1.03-1.72, P?=?0.029)), with the association largely restricted to females (HR (95% CI)=2.02 (1.28-3.17, P=0.002)). 5269 hsa-mir-374a Carcinoma, Non-Small-Cell Lung 21748820 The authors show that low expression of miR-374a in early-stage NSCLC is associated with poor patient survival. Theresults demonstrate that expression of miR-374a at early stages of NSCLC progression can serve as a prognostic marker for patient risk stratification and may be a promising therapeutic target for the treatment of lung cancer. 5270 hsa-mir-21 Carcinoma, Hepatocellular 21749846 In the 10-patient group, plasma microRNA-21 levels significantly diminished after surgery compared with the pre-operative values (p=0.0125). Plasma microRNA-21 level in the 126 patients with hepatocellular carcinoma was significantly higher than in patients with chronic hepatitis and healthy volunteers (p<0.0001, p<0.0001, respectively). ROC analysis of plasma microRNA-21 yielded an AUC of 0.773 with 61.1% sensitivity and 83.3% specificity when differentiating hepatocellular carcinoma from chronic hepatitis, and an AUC of 0.953 with 87.3% sensitivity and 92.0% specificity when differentiating hepatocellular carcinoma from healthy volunteers. 5271 hsa-mir-22 Carcinoma, Hepatocellular 21750200 miR-22 promotes HBV related hepatocellular carcinoma development in males. 5272 hsa-mir-7-1 Carcinoma, Non-Small-Cell Lung 21750649 MicroRNA-7 inhibits the growth of human non-small cell lung cancer A549 cells through targeting BCL-2. 5273 hsa-mir-7-2 Carcinoma, Non-Small-Cell Lung 21750649 MicroRNA-7 inhibits the growth of human non-small cell lung cancer A549 cells through targeting BCL-2. 5274 hsa-mir-7-3 Carcinoma, Non-Small-Cell Lung 21750649 MicroRNA-7 inhibits the growth of human non-small cell lung cancer A549 cells through targeting BCL-2. 5275 hsa-mir-122 Carcinoma, Hepatocellular 21750653 The down-regulation of miR-122 activated the CDK4-PSMD10-UPR pathway to decrease tumor cell anticancer drug-mediated apoptosis. 5276 hsa-mir-155 Hepatitis C 21750860 Coordinated increase of miRNA-155 and miRNA-196b expression correlates with the detection of the antigenomic strand of hepatitis C virus in peripheral blood mononuclear cells. 5277 hsa-mir-196b Hepatitis C 21750860 Coordinated increase of miRNA-155 and miRNA-196b expression correlates with the detection of the antigenomic strand of hepatitis C virus in peripheral blood mononuclear cells. 5278 hsa-mir-215 Colorectal Neoplasms 21752725 miR-215 has a unique potential as a prognostic biomarker in stage II and III colon cancer. 5279 hsa-mir-1-1 Thyroid Neoplasms 21752897 MiR-1 suppress Thyroid Cancer by Targeting CCND2, CXCR4, and SDF-1{alpha} 5280 hsa-mir-1-2 Thyroid Neoplasms 21752897 MiR-1 suppress Thyroid Cancer by Targeting CCND2, CXCR4, and SDF-1{alpha} 5281 hsa-mir-375 Carcinoma, Squamous Cell 21753766 Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC). 5282 hsa-mir-103a-1 Hypertension 21753805 MicroRNA-130a Mediates Proliferation of Vascular Smooth Muscle Cells in Hypertension. 5283 hsa-mir-103a-2 Hypertension 21753805 MicroRNA-130a Mediates Proliferation of Vascular Smooth Muscle Cells in Hypertension. 5284 hsa-mir-18a Breast Neoplasms 21755340 miR-18a expression was much higher in ERa-negative than in ERa-positive tumors (P < 0.0001), with the expression levels of miR-18a not differing in ERa-positive breast cancer as a function of ERa protein level. 5285 hsa-mir-193b Breast Neoplasms 21755340 The expression levels of miR-193b and miR-221 were significantly lower in ERa-negative than in ERa-positive tumors (P = 0.0015 and P = 0.0045, respectively), and the levels of these miRNAs gradually increased as ERa protein expression increased. 5286 hsa-mir-221 Breast Neoplasms 21755340 The expression levels of miR-193b and miR-221 were significantly lower in ERa-negative than in ERa-positive tumors (P = 0.0015 and P = 0.0045, respectively), and the levels of these miRNAs gradually increased as ERa protein expression increased. 5287 hsa-mir-18b Breast Neoplasms 21755340 Low miR-18b expression was significantly associated with improved survival in HER2-negative breast cancer, although miR-18b expression was not correlated with ERa protein expression. 5288 hsa-mir-542 Neoplasms 21756784 miR-542-3p affects carcinogenesis induced by anti-benzo(a) pyrene-7,8-diol-9,10-epoxide 5289 hsa-mir-21 Adenocarcinoma 21757972 Elevated microRNA miR-21 Levels in Pancreatic Cyst Fluid Are Predictive of Mucinous Precursor Lesions of Ductal Adenocarcinoma. 5290 hsa-mir-21 Breast Neoplasms 21761201 3,3'-Diindolylmethane inhibits breast cancer cell growth via miR-21-mediated Cdc25A degradation. 5291 hsa-mir-130b Multiple Myeloma 21761344 miR-130b, miR-181a, and miR-636 to be differentially expressed between GC-sensitive and GC-resistant MM.1 cell lines. 5292 hsa-mir-636 Multiple Myeloma 21761344 miR-130b, miR-181a, and miR-636 to be differentially expressed between GC-sensitive and GC-resistant MM.1 cell lines. 5293 hsa-mir-181a-1 Multiple Myeloma 21761344 miR-130b, miR-181a, and miR-636 to be differentially expressed between GC-sensitive and GC-resistant MM.1 cell lines. 5294 hsa-mir-181a-2 Multiple Myeloma 21761344 miR-130b, miR-181a, and miR-636 to be differentially expressed between GC-sensitive and GC-resistant MM.1 cell lines. 5295 hsa-mir-155 Carcinoma, Hepatocellular 21762537 ectopic expression of miR-155 upregulated the expression of several IFN-inducible antivirus genes in human hepatoma cells. 5296 hsa-mir-155 Lung Neoplasms 21762626 miR-155 could significantly inhibit the growth of human lung cancer 95D cells in vitro, which might be closely related to miR-155 induced G0/G1 phase arrest. 5297 hsa-mir-29c Carcinoma, Hepatocellular 21763284 miR-29c targets TNFAIP3, inhibits cell proliferation and induces apoptosis in hepatitis B virus-related hepatocellular carcinoma. 5298 hsa-mir-26a-1 Cerebral Hemorrhage 21764522 Circulating miR-26a is a potential predictors and therapeutic targets for non-hypertensive ICH (intracerebral hemorrhage). 5299 hsa-mir-26a-2 Cerebral Hemorrhage 21764522 Circulating miR-26a is a potential predictors and therapeutic targets for non-hypertensive ICH (intracerebral hemorrhage). 5300 hsa-mir-216a Fatty Liver 21764575 altered expression 5301 hsa-mir-216b Fatty Liver 21764575 altered expression 5302 hsa-mir-302a Fatty Liver 21764575 altered expression 5303 hsa-mir-133a-1 Hypertension 21769867 MiR-133a regulates collagen 1A1, which has potential role in myocardial fibrosis in angiotensin II dependent hypertension. 5304 hsa-mir-138-1 Carcinoma, Squamous Cell 21770894 MicroRNA-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines. 5305 hsa-mir-138-2 Carcinoma, Squamous Cell 21770894 MicroRNA-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines. 5306 hsa-mir-155 Hypertrophy 21771600 the C allele of rs5186 was associated with a significant increase in SWT (p=0.003) and LVM (p=0.001). This functional polymorphism increases expression of AGTR1 by altering the binding site for miR-155 5307 hsa-mir-155 Hypertrophy 21771600 A polymorphic miR-155 binding site ( rs5186) in AGTR1 is associated with cardiac hypertrophy in Friedreich ataxia. 5308 hsa-mir-21 Medulloblastoma 21775132 MicroRNA-21 suppression impedes medulloblastoma cell migration. 5309 hsa-mir-21 Fibrosis 21775484 miR-21 expression was upregulated in response to treatment with TGF-beta1 or TNF-alpha in human renal tubular epithelial cells in vitro. 5310 hsa-mir-21 Fibrosis 21775484 miR-21 expression was upregulated in response to treatment with TGF-beta1 or TNF-alpha in human renal tubular epithelial cells in vitro. 5311 hsa-mir-125a Lung Neoplasms 21777146 MicroRNA HSA-miR-125a-5p induces apoptosis by activating p53 in lung cancer cells. 5312 hsa-mir-16-1 Lymphoma 21778999 Hypoxia-microRNA-16 downregulation induces VEGF expression in anaplastic lymphoma kinase (ALK)-positive anaplastic large-cell lymphomas. 5313 hsa-mir-16-2 Lymphoma 21778999 Hypoxia-microRNA-16 downregulation induces VEGF expression in anaplastic lymphoma kinase (ALK)-positive anaplastic large-cell lymphomas. 5314 hsa-mir-122 Thyroid Neoplasms 21779480 The miRNA increased 8.9-fold (P < 0.05) in all Thyroid Neoplasms versus normal. 5315 hsa-mir-375 Pancreatic Neoplasms 21779484 The miRNA is Potentially Associated with Antiproliferative Activity of Benzyl Isothiocyanate in Pancreatic Cancer 5316 hsa-mir-221 Pancreatic Neoplasms 21779484 The miRNA is Potentially Associated with Antiproliferative Activity of Benzyl Isothiocyanate in Pancreatic Cancer 5317 hsa-mir-10a Leukemia, Myeloid, Acute 21784052 miR-10a overexpression is associated with NPM1 mutations and MDM4 downregulation in intermediate-risk acute myeloid leukemia. 5318 hsa-mir-122 Carcinoma, Renal Cell 21784468 Overexpression 5319 hsa-mir-155 Carcinoma, Renal Cell 21784468 Overexpression 5320 hsa-mir-210 Carcinoma, Renal Cell 21784468 Overexpression 5321 hsa-mir-200c Carcinoma, Renal Cell 21784468 Underexpression 5322 hsa-mir-335 Carcinoma, Renal Cell 21784468 Underexpression 5323 hsa-mir-218-1 Carcinoma, Renal Cell 21784468 Underexpression 5324 hsa-mir-218-2 Carcinoma, Renal Cell 21784468 Underexpression 5325 hsa-mir-29a Fibrosis 21784902 TGF-{beta}/Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29. 5326 hsa-mir-29b-1 Fibrosis 21784902 TGF-{beta}/Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29. 5327 hsa-mir-29b-2 Fibrosis 21784902 TGF-{beta}/Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29. 5328 hsa-mir-29c Fibrosis 21784902 TGF-{beta}/Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29. 5329 hsa-mir-99a Pancreatic Neoplasms 21785383 Differentially expressed miRNAs including miR-99a, miR-100, miR-125b, miR-192, and miR-429 were detected in pancreatic cancer stem cells. 5330 hsa-mir-100 Pancreatic Neoplasms 21785383 Differentially expressed miRNAs including miR-99a, miR-100, miR-125b, miR-192, and miR-429 were detected in pancreatic cancer stem cells. 5331 hsa-mir-192 Pancreatic Neoplasms 21785383 Differentially expressed miRNAs including miR-99a, miR-100, miR-125b, miR-192, and miR-429 were detected in pancreatic cancer stem cells. 5332 hsa-mir-429 Pancreatic Neoplasms 21785383 Differentially expressed miRNAs including miR-99a, miR-100, miR-125b, miR-192, and miR-429 were detected in pancreatic cancer stem cells. 5333 hsa-mir-125b-1 Pancreatic Neoplasms 21785383 Differentially expressed miRNAs including miR-99a, miR-100, miR-125b, miR-192, and miR-429 were detected in pancreatic cancer stem cells. 5334 hsa-mir-125b-2 Pancreatic Neoplasms 21785383 Differentially expressed miRNAs including miR-99a, miR-100, miR-125b, miR-192, and miR-429 were detected in pancreatic cancer stem cells. 5335 hsa-mir-373 Colorectal Neoplasms 21785829 Epigenetic silencing of microRNA-373 plays an important role in regulating cell proliferation in colon cancer. 5336 hsa-mir-203 Carcinoma, Hepatocellular 21786180 miR-203 expression predicts outcome after liver transplantation for hepatocellular carcinoma in cirrhotic liver. 5337 hsa-mir-138-1 Carcinoma, Non-Small-Cell Lung 21787234 miR-138 could play an important role in the development of cisplatin resistance in non-small cell lung cancer (NSCLC) 5338 hsa-mir-138-2 Carcinoma, Non-Small-Cell Lung 21787234 miR-138 could play an important role in the development of cisplatin resistance in non-small cell lung cancer (NSCLC) 5339 hsa-mir-205 Breast Neoplasms 21787752 ErbB2 down-regulates microRNA-205 in breast cancer. 5340 hsa-mir-155 Encephalomyelitis, Autoimmune, Experimental 21788439 Silencing MicroRNA-155 Ameliorates Experimental Autoimmune Encephalomyelitis. 5341 hsa-mir-24-1 Myocardial Infarction 21788589 MicroRNA-24 Regulates Vascularity After Myocardial Infarction 5342 hsa-mir-24-2 Myocardial Infarction 21788589 MicroRNA-24 Regulates Vascularity After Myocardial Infarction 5343 hsa-mir-125a Abortion, Habitual 21788734 Two common SNPs (rs41275794, rs12976445) in pri-miR-125a alter the mature miRNA expression and associate with Abortion, Habitual in a Han-Chinese population. 5344 hsa-mir-135b Osteosarcoma 21789031 deregulated 5345 hsa-mir-150 Osteosarcoma 21789031 deregulated 5346 hsa-mir-542 Osteosarcoma 21789031 miR-542-5p: deregulated 5347 hsa-mir-652 Osteosarcoma 21789031 deregulated 5348 hsa-mir-146b Lung Neoplasms 21789255 Overexpression of the Lung Cancer-Prognostic miR-146b MicroRNAs Has a Minimal and Negative Effect on the Malignant Phenotype of A549 Lung Cancer Cells. 5349 hsa-mir-146a Periodontal Diseases 21789961 hsa-miRNA-146a, hsa-miRNA-146b, and hsa-miRNA-155, showed significant differences between inflamed and healthy gingiva. 5350 hsa-mir-146b Periodontal Diseases 21789961 hsa-miRNA-146a, hsa-miRNA-146b, and hsa-miRNA-155, showed significant differences between inflamed and healthy gingiva. 5351 hsa-mir-155 Periodontal Diseases 21789961 hsa-miRNA-146a, hsa-miRNA-146b, and hsa-miRNA-155, showed significant differences between inflamed and healthy gingiva. 5352 hsa-mir-143 Urinary Bladder Neoplasms 21790228 Expression of miR-143 Reduces Growth and Migration of Human Bladder Carcinoma Cells by Targeting Cyclooxygenase-2. 5353 hsa-mir-29b-1 Carcinoma, Hepatocellular 21793034 MicroRNA-29b suppresses tumor angiogenesis, invasion and metastasis by regulating MMP-2 expression. 5354 hsa-mir-29b-2 Carcinoma, Hepatocellular 21793034 MicroRNA-29b suppresses tumor angiogenesis, invasion and metastasis by regulating MMP-2 expression. 5355 hsa-mir-186 Medulloblastoma 21793975 deletion 5356 hsa-mir-135a-1 Medulloblastoma 21793975 deletion 5357 hsa-mir-548d-1 Medulloblastoma 21793975 deletion 5358 hsa-mir-548d-2 Medulloblastoma 21793975 deletion 5359 hsa-mir-512-2 Medulloblastoma 21793975 deletion. Antisense-based knockdown of miR-512-5p (mature sequence of miR-512-2) resulted in significant upregulation of MYCC expression in HeLa and A549 cells, while forced overexpression of miR-512-2 in medulloblastoma/PNET cell lines DAOY, UW-228-2, PFSK resulted in downregulation of MYCC protein. 5360 hsa-mir-135a-2 Medulloblastoma 21793975 deletion or amplification 5361 hsa-mir-135b Medulloblastoma 21793975 deletion or amplification 5362 hsa-mir-33b Medulloblastoma 21793975 deletion, amplification or a mutation at the precursor miRNA 5363 hsa-mir-19b-1 Lupus Erythematosus, Systemic 21794077 Down-regulation of miR-19b and miR-20a observed in patients with SLE and SAF could contribute to increase TF expression and thus provoke the hypercoagulable state characteristic of these patients. 5364 hsa-mir-20a Lupus Erythematosus, Systemic 21794077 Down-regulation of miR-19b and miR-20a observed in patients with SLE and SAF could contribute to increase TF expression and thus provoke the hypercoagulable state characteristic of these patients. 5365 hsa-mir-19b-1 Antiphospholipid Syndrome 21794077 Down-regulation of miR-19b and miR-20a observed in patients with SLE and SAF could contribute to increase TF expression and thus provoke the hypercoagulable state characteristic of these patients. 5366 hsa-mir-20a Antiphospholipid Syndrome 21794077 Down-regulation of miR-19b and miR-20a observed in patients with SLE and SAF could contribute to increase TF expression and thus provoke the hypercoagulable state characteristic of these patients. 5367 hsa-mir-19b-1 Lupus Erythematosus, Systemic 21794077 Down-regulation of miR-19b and miR-20a observed in patients with SLE and APS could contribute to increased TF expression and thus provoke the hypercoagulable state characteristic of these patients. 5368 hsa-mir-20a Lupus Erythematosus, Systemic 21794077 Down-regulation of miR-19b and miR-20a observed in patients with SLE and APS could contribute to increased TF expression and thus provoke the hypercoagulable state characteristic of these patients. 5369 hsa-mir-19b-1 Antiphospholipid Syndrome 21794077 Down-regulation of miR-19b and miR-20a observed in patients with SLE and APS could contribute to increased TF expression and thus provoke the hypercoagulable state characteristic of these patients. 5370 hsa-mir-20a Antiphospholipid Syndrome 21794077 Down-regulation of miR-19b and miR-20a observed in patients with SLE and APS could contribute to increased TF expression and thus provoke the hypercoagulable state characteristic of these patients. 5371 hsa-mir-142 Kidney Failure, Chronic 21794090 Differential expression was detected for miR-142-3p, miR-204, miR-107 and miR-211 (p < 0.001) and miR-32 (p < 0.05). Furthermore, differential expression of miR-142-3p (p < 0.01), miR-204 (p < 0.01) and miR-211 (p < 0.05) was also observed between patient groups in urine samples. 5372 hsa-mir-204 Kidney Failure, Chronic 21794090 Differential expression was detected for miR-142-3p, miR-204, miR-107 and miR-211 (p < 0.001) and miR-32 (p < 0.05). Furthermore, differential expression of miR-142-3p (p < 0.01), miR-204 (p < 0.01) and miR-211 (p < 0.05) was also observed between patient groups in urine samples. 5373 hsa-mir-211 Kidney Failure, Chronic 21794090 Differential expression was detected for miR-142-3p, miR-204, miR-107 and miR-211 (p < 0.001) and miR-32 (p < 0.05). Furthermore, differential expression of miR-142-3p (p < 0.01), miR-204 (p < 0.01) and miR-211 (p < 0.05) was also observed between patient groups in urine samples. 5374 hsa-mir-107 Kidney Failure, Chronic 21794090 Differential expression was detected for miR-142-3p, miR-204, miR-107 and miR-211 (p < 0.001) and miR-32 (p < 0.05). 5375 hsa-mir-32 Kidney Failure, Chronic 21794090 Differential expression was detected for miR-142-3p, miR-204, miR-107 and miR-211 (p < 0.001) and miR-32 (p < 0.05). 5376 hsa-mir-218-1 Carcinoma, Squamous Cell 21795477 The tumor suppressive microRNA miR-218 targets the mTOR component Rictor and inhibits AKT phosphorylation in oral cancer. 5377 hsa-mir-218-2 Carcinoma, Squamous Cell 21795477 The tumor suppressive microRNA miR-218 targets the mTOR component Rictor and inhibits AKT phosphorylation in oral cancer. 5378 hsa-mir-17 Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma 5379 hsa-mir-18a Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma 5380 hsa-mir-19a Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma 5381 hsa-mir-20a Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma 5382 hsa-mir-19b-1 Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma 5383 hsa-mir-92a-1 Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma 5384 hsa-mir-210 Pre-Eclampsia 21801864 miR-210 Targets Iron-Sulfur Cluster Scaffold Homologue 5385 hsa-mir-491 Hepatitis C 21802413 miR-491 was involved in regulation of HCV replication via the PI3 kinase/Akt pathway. 5386 hsa-mir-122 Carcinoma, Hepatocellular 21802841 MicroRNA-122 sensitizes HCC cancer cells to adriamycin and vincristine through modulating expression of MDR and inducing cell cycle arrest. 5387 hsa-mir-17 Lymphoma, B-Cell 21803762 miR-17-5p is upregulated. 5388 hsa-mir-20a Lymphoma, B-Cell 21803762 miR-20a is upregulated. 5389 hsa-mir-9-1 Lymphoma, B-Cell 21803762 miR-9 is upregulated. 5390 hsa-mir-9-2 Lymphoma, B-Cell 21803762 miR-9 is upregulated. 5391 hsa-mir-9-3 Lymphoma, B-Cell 21803762 miR-9 is upregulated. 5392 hsa-mir-199a-1 Lymphoma, B-Cell 21803762 miR-9 is upregulated. 5393 hsa-mir-199a-2 Lymphoma, B-Cell 21803762 miR-9 is upregulated. 5394 hsa-mir-214 Lymphoma, B-Cell 21803762 miR-9 is upregulated. 5395 hsa-mir-193b Lymphoma, B-Cell 21803762 miR-9 is upregulated. 5396 hsa-mir-145 Lymphoma, B-Cell 21803762 miR-9 is upregulated. 5397 hsa-mir-103a-1 Pain 21804529 knocking-down or over-expressing miR-103, respectively, up- or down-regulate the level of Cav1.2-LTC translation.miR-103 knockdown in naive rats results in hypersensitivity to pain. Moreover, we demonstrate that miR-103 is down-regulated in neuropathic animals and that miR-103 intrathecal applications successfully relieve pain, identifying miR-103 as a novel possible therapeutic target in neuropathic chronic pain. 5398 hsa-mir-103a-2 Pain 21804529 knocking-down or over-expressing miR-103, respectively, up- or down-regulate the level of Cav1.2-LTC translation.miR-103 knockdown in naive rats results in hypersensitivity to pain. Moreover, we demonstrate that miR-103 is down-regulated in neuropathic animals and that miR-103 intrathecal applications successfully relieve pain, identifying miR-103 as a novel possible therapeutic target in neuropathic chronic pain. 5399 hsa-mir-155 Acute Coronary Syndrome 21804579 The altered expression of inflammation-related microRNAs with microRNA-155 expression correlates with Th17 differentiation in patients with acute coronary syndrome. 5400 hsa-mir-21 Colorectal Neoplasms 21806946 Neurotensin Signaling Activates MicroRNAs -21 and -155 and Akt, Promotes Tumor Growth in Mice, and is Increased in Human Colon Tumors. 5401 hsa-mir-155 Colorectal Neoplasms 21806946 Neurotensin Signaling Activates MicroRNAs -21 and -155 and Akt, Promotes Tumor Growth in Mice, and is Increased in Human Colon Tumors. 5402 hsa-mir-1-1 Acute Coronary Syndrome 21806992 The miRNA was independently associated with hsTnT levels. 5403 hsa-mir-1-2 Acute Coronary Syndrome 21806992 The miRNA was independently associated with hsTnT levels. 5404 hsa-mir-133a-1 Acute Coronary Syndrome 21806992 The miRNA was independently associated with hsTnT levels. Its level was significantly associated with the risk of death in univariate and age- and gender-adjusted analyses. 5405 hsa-mir-133a-2 Acute Coronary Syndrome 21806992 The miRNA was independently associated with hsTnT levels. Its level was significantly associated with the risk of death in univariate and age- and gender-adjusted analyses. 5406 hsa-mir-133b Acute Coronary Syndrome 21806992 The miRNA was independently associated with hsTnT levels. 5407 hsa-mir-208b Acute Coronary Syndrome 21806992 The miRNA was independently associated with hsTnT levels. Its level was significantly associated with the risk of death in univariate and age- and gender-adjusted analyses. 5408 hsa-mir-1-1 Acute Coronary Syndrome 21806992 miR-1, miR-133a, miR-133b, and miR-208b were independently associated with hsTnT levels (all P<0.001). Patients with myocardial infarction presented with higher levels of miR-1, miR-133a, and miR-208b compared with patients with unstable angina. 5409 hsa-mir-1-2 Acute Coronary Syndrome 21806992 miR-1, miR-133a, miR-133b, and miR-208b were independently associated with hsTnT levels (all P<0.001). Patients with myocardial infarction presented with higher levels of miR-1, miR-133a, and miR-208b compared with patients with unstable angina. 5410 hsa-mir-133a-1 Acute Coronary Syndrome 21806992 miR-1, miR-133a, miR-133b, and miR-208b were independently associated with hsTnT levels (all P<0.001). Patients with myocardial infarction presented with higher levels of miR-1, miR-133a, and miR-208b compared with patients with unstable angina. 5411 hsa-mir-133a-2 Acute Coronary Syndrome 21806992 miR-1, miR-133a, miR-133b, and miR-208b were independently associated with hsTnT levels (all P<0.001). Patients with myocardial infarction presented with higher levels of miR-1, miR-133a, and miR-208b compared with patients with unstable angina. 5412 hsa-mir-133b Acute Coronary Syndrome 21806992 miR-1, miR-133a, miR-133b, and miR-208b were independently associated with hsTnT levels (all P<0.001). Patients with myocardial infarction presented with higher levels of miR-1, miR-133a, and miR-208b compared with patients with unstable angina. 5413 hsa-mir-208b Acute Coronary Syndrome 21806992 miR-1, miR-133a, miR-133b, and miR-208b were independently associated with hsTnT levels (all P<0.001). Patients with myocardial infarction presented with higher levels of miR-1, miR-133a, and miR-208b compared with patients with unstable angina. 5414 hsa-mir-142 Psoriasis 21807764 miR-142-3p: deregulated 5415 hsa-mir-223 Psoriasis 21807764 miR-223 and miR-223*: deregulated 5416 hsa-mir-21 Psoriasis 21807764 deregulated 5417 hsa-mir-378a Psoriasis 21807764 deregulated 5418 hsa-mir-100 Psoriasis 21807764 deregulated 5419 hsa-mir-132 Supranuclear Palsy, Progressive 21807765 MicroRNA-132 loss is associated with tau exon 10 inclusion in Supranuclear Palsy, Progressive. 5420 hsa-mir-199a-1 Carcinoma, Hepatocellular 21807947 MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. 5421 hsa-mir-199a-2 Carcinoma, Hepatocellular 21807947 MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. 5422 hsa-mir-199a-1 Urinary Bladder Neoplasms 21807947 MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. 5423 hsa-mir-199a-2 Urinary Bladder Neoplasms 21807947 MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. 5424 hsa-mir-494 Cholangiocarcinoma 21809359 miRNA-494 downregulated in human cholangiocarcinoma controls cell cycle through multiple targets involved in the G1/S checkpoint. 5425 hsa-mir-637 Carcinoma, Hepatocellular 21809363 Primate-specific miRNA-637 inhibits tumorigenesis in hepatocellular carcinoma by disrupting stat3 signaling. 5426 hsa-mir-146a Arthritis, Rheumatoid 21810022 miRNA 146a expression was significantly higher in patients with RA than in those with OA and in controls.In patients with RA, miRNA 146a positively correlated with TNF-a (p=0.0003), erythrocyte sedimentation rate (ESR)(p=0.022), and DAS 28 (p=0.009). 5427 hsa-mir-367 Breast Neoplasms 21810988 Functional SNP (rs1044129, is present in binding region) in the microRNA-367 binding site in the 3'UTR of the calcium channel ryanodine receptor gene 3 (RYR3) affects breast cancer risk and calcification. 5428 hsa-mir-375 Carcinoma, Squamous Cell 21813472 MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor. 5429 hsa-mir-34a Breast Neoplasms 21814748 Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA. 5430 hsa-mir-196a-2 Colorectal Neoplasms 21815818 A Functional Polymorphism (rs11614913 (T>C)) in miRNA-196a2 Is Associated with Colorectal Cancer Risk in a Chinese Population. 5431 hsa-mir-32 Leukemia, Myeloid 21816906 MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis. 5432 hsa-mir-17 Retinoblastoma 21816922 miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. 5433 hsa-mir-18a Retinoblastoma 21816922 miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. 5434 hsa-mir-19a Retinoblastoma 21816922 miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. 5435 hsa-mir-20a Retinoblastoma 21816922 miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. 5436 hsa-mir-19b-1 Retinoblastoma 21816922 miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. 5437 hsa-mir-92a-1 Retinoblastoma 21816922 miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. 5438 hsa-mir-21 Atherosclerosis 21817107 MicroRNA-21 Regulates Vascular Smooth Muscle Cell Function via Targeting Tropomyosin 1 in Arteriosclerosis Obliterans of Lower Extremities. 5439 hsa-mir-100 Atherosclerosis 21817153 deregulated 5440 hsa-mir-127 Atherosclerosis 21817153 deregulated 5441 hsa-mir-145 Atherosclerosis 21817153 deregulated 5442 hsa-mir-133a-1 Atherosclerosis 21817153 deregulated 5443 hsa-mir-133a-2 Atherosclerosis 21817153 deregulated 5444 hsa-mir-133b Atherosclerosis 21817153 deregulated 5445 hsa-mir-101-1 Ovarian Neoplasms 21818714 MicroRNA-101 Inhibits Growth of Epithelial Ovarian Cancer by Relieving Chromatin-Mediated Transcriptional Repression of p21(waf1/cip1). 5446 hsa-mir-101-2 Ovarian Neoplasms 21818714 MicroRNA-101 Inhibits Growth of Epithelial Ovarian Cancer by Relieving Chromatin-Mediated Transcriptional Repression of p21(waf1/cip1). 5447 hsa-mir-196a-1 Leukemia, Myeloid, Acute 21818844 High miR-196a and -b expression was observed in patients carrying MLL gene rearrangements, NPM1 mutations, or FLT3-ITD in a cytogenetically normal background, compared to all other patients. In contrast, CEBPA mutated cases had a low expression of miR-196a and -b. Expression of miR-196a and -b was correlated with expression of neighboring HOXA and HOXB genes. 5448 hsa-mir-196a-2 Leukemia, Myeloid, Acute 21818844 High miR-196a and -b expression was observed in patients carrying MLL gene rearrangements, NPM1 mutations, or FLT3-ITD in a cytogenetically normal background, compared to all other patients. In contrast, CEBPA mutated cases had a low expression of miR-196a and -b. Expression of miR-196a and -b was correlated with expression of neighboring HOXA and HOXB genes. 5449 hsa-mir-196b Leukemia, Myeloid, Acute 21818844 High miR-196a and -b expression was observed in patients carrying MLL gene rearrangements, NPM1 mutations, or FLT3-ITD in a cytogenetically normal background, compared to all other patients. In contrast, CEBPA mutated cases had a low expression of miR-196a and -b. Expression of miR-196a and -b was correlated with expression of neighboring HOXA and HOXB genes. 5450 hsa-mir-29a Leukemia, Myeloid, Acute 21818844 Lower miR-29a expression was mainly observed in MLL-rearranged pediatric acute myeloid leukemia, specifically in cases carrying t(10;11). 5451 hsa-mir-106b Laryngeal Neoplasms 21819631 MiR-106b promotes cell proliferation via targeting RB in laryngeal carcinoma. 5452 hsa-mir-21 Carcinoma, Renal Cell 21820586 miR-21 Modulates Cell Apoptosis by Targeting Multiple Genes in Renal Cell Carcinoma. 5453 hsa-mir-21 Breast Neoplasms 21820606 MicroRNA-21 Modulates Chemosensitivity of Breast Cancer Cells to?Doxorubicin by Targeting PTEN. 5454 hsa-mir-21 Atherosclerosis 21820659 miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques (compared to non-atherosclerotic left internal thoracic arteries (LITA)) in the Tampere Vascular Study. 5455 hsa-mir-210 Atherosclerosis 21820659 miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques (compared to non-atherosclerotic left internal thoracic arteries (LITA)) in the Tampere Vascular Study. 5456 hsa-mir-34a Atherosclerosis 21820659 miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques (compared to non-atherosclerotic left internal thoracic arteries (LITA)) in the Tampere Vascular Study. 5457 hsa-mir-146a Atherosclerosis 21820659 miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques (compared to non-atherosclerotic left internal thoracic arteries (LITA)) in the Tampere Vascular Study. 5458 hsa-mir-146b Atherosclerosis 21820659 miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques (compared to non-atherosclerotic left internal thoracic arteries (LITA)) in the Tampere Vascular Study. 5459 hsa-mir-335 Stomach Neoplasms 21822301 MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1. 5460 hsa-mir-542 Colorectal Neoplasms 21822307 A common single-nucleotide polymorphism (T8473CA) in cyclooxygenase-2 disrupts microRNA (miR-542-3p)-mediated regulation. 5461 hsa-mir-146b Pancreatic Neoplasms 21823013 miR-146b-5p has inhibitory effects of on cell migration and invasion of pancreatic cancer by targeting MMP16. 5462 hsa-mir-125b-1 Ovarian Neoplasms 21823019 miR-125b confers resistance of ovarian cancer cells to cisplatin by targeting pro-apoptotic Bcl-2 antagonist killer 1. 5463 hsa-mir-125b-2 Ovarian Neoplasms 21823019 miR-125b confers resistance of ovarian cancer cells to cisplatin by targeting pro-apoptotic Bcl-2 antagonist killer 1. 5464 hsa-mir-21 Prostatic Neoplasms 21826097 Spry1 is a target for miR-21-mediated gene silencing. 5465 hsa-mir-214 Pancreatic Neoplasms 21826251 preferential expression in holoclones 5466 hsa-mir-21 Pancreatic Neoplasms 21826251 preferential expression in holoclones 5467 hsa-mir-221 Pancreatic Neoplasms 21826251 preferential expression in holoclones 5468 hsa-mir-222 Pancreatic Neoplasms 21826251 preferential expression in holoclones 5469 hsa-mir-155 Pancreatic Neoplasms 21826251 preferential expression in holoclones 5470 hsa-mir-182 Colorectal Neoplasms 21826996 upregulated in colon cancer compared to normal colonic mucosa 5471 hsa-mir-17 Colorectal Neoplasms 21826996 upregulated in colon cancer compared to normal colonic mucosa 5472 hsa-mir-106a Colorectal Neoplasms 21826996 upregulated in colon cancer compared to normal colonic mucosa 5473 hsa-mir-93 Colorectal Neoplasms 21826996 upregulated in colon cancer compared to normal colonic mucosa 5474 hsa-mir-200c Colorectal Neoplasms 21826996 upregulated in colon cancer compared to normal colonic mucosa 5475 hsa-mir-92a-1 Colorectal Neoplasms 21826996 upregulated in colon cancer compared to normal colonic mucosa 5476 hsa-mir-92a-2 Colorectal Neoplasms 21826996 upregulated in colon cancer compared to normal colonic mucosa 5477 hsa-let-7a-1 Colorectal Neoplasms 21826996 upregulated in colon cancer compared to normal colonic mucosa 5478 hsa-let-7a-2 Colorectal Neoplasms 21826996 upregulated in colon cancer compared to normal colonic mucosa 5479 hsa-let-7a-3 Colorectal Neoplasms 21826996 upregulated in colon cancer compared to normal colonic mucosa 5480 hsa-mir-20a Colorectal Neoplasms 21826996 upregulated in colon cancer compared to normal colonic mucosa 5481 hsa-mir-143 Colorectal Neoplasms 21826996 downregulated in colon cancer compared to normal colonic mucosa 5482 hsa-mir-145 Colorectal Neoplasms 21826996 downregulated in colon cancer compared to normal colonic mucosa 5483 hsa-mir-451a Diabetic Nephropathies 21827757 MicroRNA-451 regulates p38 MAPK signaling by targeting of Ywhaz and suppresses the mesangial hypertrophy in early Diabetic Nephropathies. 5484 hsa-mir-214 Breast Neoplasms 21828058 Decreased MicroRNA-214 Levels In Breast Cancer Cells Coincides with Increased Cell Proliferation, Invasion, and Accumulation of the Polycomb Ezh2 Methyltransferase. 5485 hsa-mir-144 Diabetes Mellitus, Type 2 21829658 MicroRNA 144 Impairs Insulin Signaling by Inhibiting the Expression of Insulin Receptor Substrate 1 in Type 2 Diabetes Mellitus. 5486 hsa-mir-26a-1 Carcinoma, Hepatocellular 21829663 miRNAs miR-26a, -29c, -146a and -190 were significantly down-regulated in a subset of HCC tissues with carboxyl-terminal HBx truncation compared to their matching non-tumor tissues. 5487 hsa-mir-26a-2 Carcinoma, Hepatocellular 21829663 miRNAs miR-26a, -29c, -146a and -190 were significantly down-regulated in a subset of HCC tissues with carboxyl-terminal HBx truncation compared to their matching non-tumor tissues. 5488 hsa-mir-29c Carcinoma, Hepatocellular 21829663 miRNAs miR-26a, -29c, -146a and -190 were significantly down-regulated in a subset of HCC tissues with carboxyl-terminal HBx truncation compared to their matching non-tumor tissues. 5489 hsa-mir-146a Carcinoma, Hepatocellular 21829663 miRNAs miR-26a, -29c, -146a and -190 were significantly down-regulated in a subset of HCC tissues with carboxyl-terminal HBx truncation compared to their matching non-tumor tissues. 5490 hsa-mir-190a Carcinoma, Hepatocellular 21829663 miRNAs miR-26a, -29c, -146a and -190 were significantly down-regulated in a subset of HCC tissues with carboxyl-terminal HBx truncation compared to their matching non-tumor tissues. 5491 hsa-mir-93 Burkitt Lymphoma 21831295 miR-93 repressed human activation induced cytidine deaminase. 5492 hsa-mir-155 Burkitt Lymphoma 21831295 miR-93 repressed human activation induced cytidine deaminase. 5493 hsa-mir-885 Glioblastoma 21831363 miR-885-5p has high positive correlation with MMP-9 expression and its upregulation was demonstrated to reduce the levels of MMP-9 expression and inhibit cellular invasion in U251 and U87 glioma cells. 5494 hsa-mir-491 Glioblastoma 21831363 miR-491-5p has high positive correlation with MMP-9 expression and its upregulation was demonstrated to reduce the levels of MMP-9 expression and inhibit cellular invasion in U251 and U87 glioma cells. Furthermore, miR-491-5p suppressed glioma cell invasion via targeting MMP-9 directly. 5495 hsa-mir-148a Amyloidosis 21834602 upregulated in bone marrow plasma cells from patients with immunoglobulin light chain (AL) amyloidosis compared with controls. 5496 hsa-mir-16-2 Amyloidosis 21834602 upregulated in bone marrow plasma cells from patients with immunoglobulin light chain (AL) amyloidosis compared with controls. 5497 hsa-mir-26a-1 Amyloidosis 21834602 upregulated in bone marrow plasma cells from patients with immunoglobulin light chain (AL) amyloidosis compared with controls. 5498 hsa-mir-26a-2 Amyloidosis 21834602 upregulated in bone marrow plasma cells from patients with immunoglobulin light chain (AL) amyloidosis compared with controls. 5499 hsa-mir-203 Urinary Bladder Neoplasms 21836020 Curcumin modulates microRNA-203 mediated regulation of the Src-Akt axis in bladder cancer. 5500 hsa-mir-145 Melanoma 21836381 MiR-145 was significantly down-regulated in canine malignant melanoma tissues. The ectopic expression of miR-145 showed a significant growth inhibition in both canine and human melanoma cells tested, and the effect was achieved partly by suppressing c-MYC in canine melanoma LMeC, and human melanoma A2058 and Mewo cells. 5501 hsa-mir-200a Carcinoma, Hepatocellular 21837748 The histone deacetylase 4/Sp1/miR-200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma. 5502 hsa-mir-100 Muscular Dystrophies 21840938 highly expressed in fetal muscle. 5503 hsa-mir-127 Muscular Dystrophies 21840938 miR-127-3p: highly expressed in fetal muscle. 5504 hsa-mir-148a Muscular Dystrophies 21840938 highly expressed in fetal muscle. 5505 hsa-mir-136 Muscular Dystrophies 21840938 miR-136*: highly expressed in fetal muscle. 5506 hsa-mir-192 Muscular Dystrophies 21840938 highly expressed in fetal muscle. 5507 hsa-mir-335 Muscular Dystrophies 21840938 highly expressed in fetal muscle. 5508 hsa-mir-376c Muscular Dystrophies 21840938 highly expressed in fetal muscle. 5509 hsa-mir-489 Muscular Dystrophies 21840938 highly expressed in fetal muscle. 5510 hsa-mir-502 Muscular Dystrophies 21840938 miR-502-3p: highly expressed in fetal muscle. 5511 hsa-mir-107 Breast Neoplasms 21841313 miR-107 promotes tumor progression by targeting the let-7 microRNA in mice and humans. 5512 hsa-mir-184 Carcinoma, Renal Cell 21844955 miR-184 show abnormal expression in human renal carcinoma. 5513 hsa-mir-194-1 Stomach Neoplasms 21845495 There is an inverse Association between miR-194 Expression and Tumor Invasion in Gastric Cancer. 5514 hsa-mir-194-2 Stomach Neoplasms 21845495 There is an inverse Association between miR-194 Expression and Tumor Invasion in Gastric Cancer. 5515 hsa-mir-637 Hypertension 21846868 ATP6V0A1 Polymorphism and MicroRNA-637 may have A Pathogenetic Role for MicroRNAs in Essential Hypertension. 5516 hsa-mir-874 Carcinoma, Squamous Cell 21847129 Tumour suppressive microRNA-874 regulates novel cancer networks in maxillary sinus squamous cell carcinoma. 5517 hsa-mir-199a-1 Carcinoma, Hepatocellular 21847633 Lentivirus-Mediated Overexpression of MicroRNA-199a Inhibits Cell Proliferation of Human Hepatocellular Carcinoma. 5518 hsa-mir-199a-2 Carcinoma, Hepatocellular 21847633 Lentivirus-Mediated Overexpression of MicroRNA-199a Inhibits Cell Proliferation of Human Hepatocellular Carcinoma. 5519 hsa-mir-101-1 Lung Neoplasms 21849855 miR-101 DNA Copy Loss is a Prominent Subtype Specific Event in Lung Cancer. 5520 hsa-mir-101-2 Lung Neoplasms 21849855 miR-101 DNA Copy Loss is a Prominent Subtype Specific Event in Lung Cancer. 5521 hsa-mir-194-1 Endometrial Neoplasms 21851624 MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1. 5522 hsa-mir-194-2 Endometrial Neoplasms 21851624 MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1. 5523 hsa-mir-708 Carcinoma, Renal Cell 21852381 MicroRNA-708 induces apoptosis and suppresses tumorigenicity in renal cancer cells. 5524 hsa-mir-21 Fibrosis 21852586 Smad3-Mediated Upregulation of miR-21 Promotes Renal Fibrosis. 5525 hsa-let-7a-1 Sarcoma, Ewing's 21853155 Let-7a Is a Direct EWS-FLI-1 Target Implicated in Ewing's Sarcoma Development. 5526 hsa-let-7a-2 Sarcoma, Ewing's 21853155 Let-7a Is a Direct EWS-FLI-1 Target Implicated in Ewing's Sarcoma Development. 5527 hsa-let-7a-3 Sarcoma, Ewing's 21853155 Let-7a Is a Direct EWS-FLI-1 Target Implicated in Ewing's Sarcoma Development. 5528 hsa-mir-375 Lung Neoplasms 21856745 miR-375 is activated by ASH1 and inhibits YAP1 in a lineage dependent manner in lung cancer. 5529 hsa-mir-126 Ischemia 21856785 MicroRNA-126 modulates endothelial SDF-1 expression and mobilization of Sca-1+/Lin- progenitor cells in ischemia. 5530 hsa-mir-9-1 Glioblastoma 21857646 CAMTA1 is a novel tumour suppressor regulated by miR-9/9(*) in glioblastoma stem cells. 5531 hsa-mir-9-2 Glioblastoma 21857646 CAMTA1 is a novel tumour suppressor regulated by miR-9/9(*) in glioblastoma stem cells. 5532 hsa-mir-9-3 Glioblastoma 21857646 CAMTA1 is a novel tumour suppressor regulated by miR-9/9(*) in glioblastoma stem cells. 5533 hsa-mir-9-1 Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. 5534 hsa-mir-9-2 Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. 5535 hsa-mir-9-3 Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. 5536 hsa-mir-302c Biliary Tract Neoplasms 21858175 The miRNA miR-302c* was significantly more highly expressed in the malignant group than in the benign group. 5537 hsa-mir-199a-1 Biliary Tract Neoplasms 21858175 The miRNA miR-199a-3p was significantly more highly expressed in the malignant group than in the benign group. 5538 hsa-mir-199a-2 Biliary Tract Neoplasms 21858175 The miRNA miR-199a-3p was significantly more highly expressed in the malignant group than in the benign group. 5539 hsa-mir-222 Biliary Tract Neoplasms 21858175 The miRNA miR-222* was significantly more highly expressed in the malignant group than in the benign group. 5540 hsa-mir-145 Biliary Tract Neoplasms 21858175 The miRNA miR-145* was significantly more highly expressed in the malignant group than in the benign group. 5541 hsa-mir-942 Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. 5542 hsa-mir-147b Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. 5543 hsa-let-7f-2 Biliary Tract Neoplasms 21858175 The miRNA let-7f-2* was significantly more highly expressed in the malignant group than in the benign group. 5544 hsa-let-7i Biliary Tract Neoplasms 21858175 The miRNA let-7i* was significantly more highly expressed in the malignant group than in the benign group. 5545 hsa-mir-105-1 Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. 5546 hsa-mir-105-2 Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. 5547 hsa-mir-494 Uterine Cervical Neoplasms 21859890 miR-494 Competitively regulates Nucleolin expression with HuR. 5548 hsa-mir-506 Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5549 hsa-mir-507 Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5550 hsa-mir-508 Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5551 hsa-mir-510 Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5552 hsa-mir-509-1 Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5553 hsa-mir-509-2 Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5554 hsa-mir-509-3 Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5555 hsa-mir-513a-1 Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5556 hsa-mir-513a-2 Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5557 hsa-mir-513b Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5558 hsa-mir-513c Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5559 hsa-mir-514a-1 Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5560 hsa-mir-514a-2 Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5561 hsa-mir-514a-3 Melanoma 21860416 miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf. 5562 hsa-mir-542 Neoplasms 21860426 downregulation of miR-542-3p is significantly correlated with the upregulation of c-Src and ILK. Our results suggest that the novel c-Src-miR-542-3p-ILK-FAK circuit plays a crucial role in controlling tumor progression. 5563 hsa-mir-21 Melanoma 21863027 PCR analysis revealed primary cutaneous melanomas had an 8.6-fold overexpression of miR-21 and a 7.5-fold overexpression of miR-155 compared with benign naevi (P<0.0001). 5564 hsa-mir-155 Melanoma 21863027 PCR analysis revealed primary cutaneous melanomas had an 8.6-fold overexpression of miR-21 and a 7.5-fold overexpression of miR-155 compared with benign naevi (P<0.0001). 5565 hsa-mir-144 Colorectal Neoplasms 21863218 Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancer. 5566 hsa-mir-224 Colorectal Neoplasms 21864507 Underexpression in methotrexate resistant human colon cancer cells. 5567 hsa-mir-326 Leukemia-Lymphoma, Adult T-Cell 21865341 induced 5568 hsa-mir-663a Leukemia-Lymphoma, Adult T-Cell 21865341 induced 5569 hsa-mir-711 Leukemia-Lymphoma, Adult T-Cell 21865341 induced 5570 hsa-mir-203 Leukemia-Lymphoma, Adult T-Cell 21865341 repressed 5571 hsa-mir-205 Leukemia-Lymphoma, Adult T-Cell 21865341 repressed 5572 hsa-mir-221 Breast Neoplasms 21868360 miR-221/222 Targeting of Trichorhinophalangeal 1 (TRPS1) Promotes Epithelial-to-Mesenchymal Transition in Breast Cancer. 5573 hsa-mir-222 Breast Neoplasms 21868360 miR-221/222 Targeting of Trichorhinophalangeal 1 (TRPS1) Promotes Epithelial-to-Mesenchymal Transition in Breast Cancer. 5574 hsa-mir-132 Myocardial Infarction 21868695 Transplantation of Human Pericyte Progenitor Cells Improves the Repair of Infarcted Heart Through Activation of an Angiogenic Program Involving Micro-RNA-132. 5575 hsa-mir-152 Endometrial Neoplasms 21868754 miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer. 5576 hsa-let-7g Breast Neoplasms 21868760 Treatment with estrogen or EGF specifically reduced the expression of mature let-7g through activation of p44/42 MAPK and subsequently stimulated expression of GAB2 and FN1, which in turn promoted tumor invasion. We thus identify let-7g as a unique member of the let-7 miRNA family which can serve as a prognostic biomarker in breast cancer and also propose a paradigm utilized by specific signaling molecules via let-7g to cooperatively promote breast cancer invasion and metastasis. 5577 hsa-let-7a-1 Mesothelioma 21869823 EphrinA1 inhibits malignant mesothelioma tumor growth via let-7 microRNA-mediated repression of the RAS oncogene.EphrinA1 activation induced several fold increases in let-7a1, let-7a3, let-7f1 and let-7f2 miRNA expression in MMCs. 5578 hsa-let-7a-3 Mesothelioma 21869823 EphrinA1 inhibits malignant mesothelioma tumor growth via let-7 microRNA-mediated repression of the RAS oncogene.EphrinA1 activation induced several fold increases in let-7a1, let-7a3, let-7f1 and let-7f2 miRNA expression in MMCs. 5579 hsa-let-7f-1 Mesothelioma 21869823 EphrinA1 inhibits malignant mesothelioma tumor growth via let-7 microRNA-mediated repression of the RAS oncogene.EphrinA1 activation induced several fold increases in let-7a1, let-7a3, let-7f1 and let-7f2 miRNA expression in MMCs. 5580 hsa-let-7f-2 Mesothelioma 21869823 EphrinA1 inhibits malignant mesothelioma tumor growth via let-7 microRNA-mediated repression of the RAS oncogene.EphrinA1 activation induced several fold increases in let-7a1, let-7a3, let-7f1 and let-7f2 miRNA expression in MMCs. 5581 hsa-mir-140 Osteoarthritis 21872590 MiR-140 is co-expressed with Wwp2-C transcript and activated by Sox9 to target Sp1 in maintaining the chondrocyte proliferation. 5582 hsa-mir-21 Colorectal Neoplasms 21872591 miR-21 targets the tumor suppressor RhoB and regulates proliferation, invasion and apoptosis in colorectal cancer cells. 5583 hsa-mir-200c Colorectal Neoplasms 21873159 Oncogenic KRAS Regulates miR-200c and miR-221/222 in a 3D-Specific Manner in Colorectal Cancer Cells. 5584 hsa-mir-221 Colorectal Neoplasms 21873159 Oncogenic KRAS Regulates miR-200c and miR-221/222 in a 3D-Specific Manner in Colorectal Cancer Cells. 5585 hsa-mir-222 Colorectal Neoplasms 21873159 Oncogenic KRAS Regulates miR-200c and miR-221/222 in a 3D-Specific Manner in Colorectal Cancer Cells. 5586 hsa-mir-145 Myelodysplastic Syndromes 21873545 miR-145 affects megakaryocyte and erythroid differentiation.Patients with del(5q) MDS have decreased expression of miR-145 and increased expression of Fli-1. Combined loss of miR-145 and RPS14 cooperate to alter erythroid-megakaryocytic differentiation in a manner similar to the 5q- syndrome. 5587 hsa-mir-149 Nasopharyngeal Neoplasms 21873783 miR-149 promotes epithelial-mesenchymal transition and invasion in nasopharyngeal carcinoma cells. 5588 hsa-mir-146b Thyroid Neoplasms 21874046 MicroRNA miR-146b-5p regulates signal transduction of TGF-beta by repressing SMAD4 in thyroid cancer. 5589 hsa-mir-128-1 Glioblastoma 21874051 Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases. 5590 hsa-mir-128-2 Glioblastoma 21874051 Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases. 5591 hsa-mir-145 Stomach Neoplasms 21874264 miR-145, miR-27a, miR-494 are differently expressed between intestinal-type and diffuse-type gastric cancers. 5592 hsa-mir-27a Stomach Neoplasms 21874264 miR-145, miR-27a, miR-494 are differently expressed between intestinal-type and diffuse-type gastric cancers. 5593 hsa-mir-494 Stomach Neoplasms 21874264 miR-145, miR-27a, miR-494 are differently expressed between intestinal-type and diffuse-type gastric cancers. 5594 hsa-mir-32 Stomach Neoplasms 21874264 miR-32,miR-182 and miR-143 dysregulated expression levels are related with different pathological stages of intestinal-type gastric cancers. 5595 hsa-mir-182 Stomach Neoplasms 21874264 miR-32,miR-182 and miR-143 dysregulated expression levels are related with different pathological stages of intestinal-type gastric cancers. 5596 hsa-mir-143 Stomach Neoplasms 21874264 miR-32,miR-182 and miR-143 dysregulated expression levels are related with different pathological stages of intestinal-type gastric cancers. 5597 hsa-mir-145 Stomach Neoplasms 21874264 miR-145, miR-27a, miR-494 are differently expressed between intestinal-type and diffuse-type gastric cancers. miR-32, miR-182 and miR-143 dysregulated expression levels are related with different pathological stages of intestinal-type gastric cancers (p<0.01). 5598 hsa-mir-27a Stomach Neoplasms 21874264 miR-145, miR-27a, miR-494 are differently expressed between intestinal-type and diffuse-type gastric cancers. miR-32, miR-182 and miR-143 dysregulated expression levels are related with different pathological stages of intestinal-type gastric cancers (p<0.01). 5599 hsa-mir-494 Stomach Neoplasms 21874264 miR-145, miR-27a, miR-494 are differently expressed between intestinal-type and diffuse-type gastric cancers. miR-32, miR-182 and miR-143 dysregulated expression levels are related with different pathological stages of intestinal-type gastric cancers (p<0.01). 5600 hsa-mir-32 Stomach Neoplasms 21874264 miR-145, miR-27a, miR-494 are differently expressed between intestinal-type and diffuse-type gastric cancers. miR-32, miR-182 and miR-143 dysregulated expression levels are related with different pathological stages of intestinal-type gastric cancers (p<0.01). 5601 hsa-mir-182 Stomach Neoplasms 21874264 miR-145, miR-27a, miR-494 are differently expressed between intestinal-type and diffuse-type gastric cancers. miR-32, miR-182 and miR-143 dysregulated expression levels are related with different pathological stages of intestinal-type gastric cancers (p<0.01). 5602 hsa-mir-143 Stomach Neoplasms 21874264 miR-145, miR-27a, miR-494 are differently expressed between intestinal-type and diffuse-type gastric cancers. miR-32, miR-182 and miR-143 dysregulated expression levels are related with different pathological stages of intestinal-type gastric cancers (p<0.01). 5603 hsa-mir-138-1 Carcinoma, Renal Cell 21875287 MiR-138 Suppresses Expression of Hypoxia-inducible factor 1a (HIF-1a) in Clear Cell Renal Cell Carcinoma 786-O Cells. 5604 hsa-mir-138-2 Carcinoma, Renal Cell 21875287 MiR-138 Suppresses Expression of Hypoxia-inducible factor 1a (HIF-1a) in Clear Cell Renal Cell Carcinoma 786-O Cells. 5605 hsa-mir-21 Multiple Sclerosis 21875645 In peripheral mononuclear cells, a statistically significant increased expression of miR-21, miR-146a and -b was observed in relapsing remitting (RR)MS patients as compared with controls. 5606 hsa-mir-146a Multiple Sclerosis 21875645 In peripheral mononuclear cells, a statistically significant increased expression of miR-21, miR-146a and -b was observed in relapsing remitting (RR)MS patients as compared with controls. 5607 hsa-mir-146b Multiple Sclerosis 21875645 In peripheral mononuclear cells, a statistically significant increased expression of miR-21, miR-146a and -b was observed in relapsing remitting (RR)MS patients as compared with controls. 5608 hsa-mir-451a Carcinoma, Non-Small-Cell Lung 21875770 This study showed that miRNA-451 expression decreased in non-small cell lung cancer (NSCLC) tissues and that its expression was negatively associated with lymph node metastasis, the stage of TNM classification and poor prognosis of NSCLC patients. Moreover, significantly different miRNA-451 expression levels were found between smoking and non-smoking patients. The overexpression of miRNA-451 inhibited cell cycle progression, cellular migration and the invasive ability of NSCLC cells.Increased miRNA-451 expression also promoted anoikis of NSCLC cells. 5609 hsa-mir-451a Carcinoma, Non-Small-Cell Lung 21875770 miRNA-451 expression decreased in non-small cell lung cancer (NSCLC) tissues and that its expression was negatively associated with lymph node metastasis, the stage of TNM classification and poor prognosis of NSCLC patients. Moreover, significantly different miRNA-451 expression levels were found between smoking and non-smoking patients. The overexpression of miRNA-451 inhibited cell cycle progression, cellular migration and the invasive ability of NSCLC cells. Increased miRNA-451 expression also promoted anoikis of NSCLC cells. Together, these data suggested that aberrantly expressed miRNA-451 may be associated with the development of NSCLC. 5610 hsa-mir-31 Neoplasms 21875932 miR-31 is a master regulator of integrins. The expression of miR-31 in cancer cells resulted in a significant repression of these integrin subunits both at the mRNA and protein levels. 5611 hsa-mir-18a Hepatitis B 21876625 potential associated miRNA 5612 hsa-mir-18b Hepatitis B 21876625 potential associated miRNA 5613 hsa-mir-221 Hepatitis B 21876625 downregulated in acute HBV infection, normally expressed in chronic HBV infection, and upregulated in HCC 5614 hsa-mir-18a Carcinoma, Hepatocellular 21876625 potential associated miRNA 5615 hsa-mir-18b Carcinoma, Hepatocellular 21876625 potential associated miRNA 5616 hsa-mir-221 Carcinoma, Hepatocellular 21876625 downregulated in acute HBV infection, normally expressed in chronic HBV infection, and upregulated in HCC 5617 hsa-mir-106a Hepatitis B 21876625 potential associated miRNA 5618 hsa-mir-106b Hepatitis B 21876625 potential associated miRNA 5619 hsa-mir-101-1 Hepatitis B 21876625 potential associated miRNA 5620 hsa-mir-101-2 Hepatitis B 21876625 potential associated miRNA 5621 hsa-mir-106a Carcinoma, Hepatocellular 21876625 potential associated miRNA 5622 hsa-mir-106b Carcinoma, Hepatocellular 21876625 potential associated miRNA 5623 hsa-mir-101-1 Carcinoma, Hepatocellular 21876625 potential associated miRNA 5624 hsa-mir-101-2 Carcinoma, Hepatocellular 21876625 potential associated miRNA 5625 hsa-mir-181b-1 Stomach Neoplasms 21876743 Doxifluridine/Oxaliplatin treated advanced stage gastric cancer patients. The expression of miR-181b and miR-21 was significantly overexpressed in gastric tumors compared to normal gastric tissues. 5626 hsa-mir-181b-2 Stomach Neoplasms 21876743 Doxifluridine/Oxaliplatin treated advanced stage gastric cancer patients. The expression of miR-181b and miR-21 was significantly overexpressed in gastric tumors compared to normal gastric tissues. 5627 hsa-mir-21 Stomach Neoplasms 21876743 Doxifluridine/Oxaliplatin treated advanced stage gastric cancer patients. The expression of miR-181b and miR-21 was significantly overexpressed in gastric tumors compared to normal gastric tissues. 5628 hsa-mir-216b Nasopharyngeal Neoplasms 21878506 miR-216b suppresses tumor growth and invasion by targeting KRAS in nasopharyngeal carcinoma. 5629 hsa-mir-99a Carcinoma, Hepatocellular 21878637 Lower miR-99a expression in HCC tissues significantly correlated with shorter survival of HCC patients, and miR-99a was identified to be an independent predictor for prognosis of HCC patients. Furthermore, restoration of miR-99a dramatically suppressed HCC cell growth in vitro by inducing G1 phase cell cycle arrest. 5630 hsa-mir-125b-2 Glioblastoma 21879257 miR-125b-2 overexpression might confer glioblastoma stem cells resistance to TMZ. 5631 hsa-mir-125b-1 Leukemia, Promyelocytic, Acute 21880154 Upregulation of microRNA-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia. 5632 hsa-mir-98 Carcinoma, Non-Small-Cell Lung 21880462 miR-98 regulates cisplatin-induced A549 cell death by inhibiting TP53 pathway. 5633 hsa-mir-15a Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5634 hsa-mir-16-1 Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5635 hsa-mir-16-2 Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5636 hsa-mir-25 Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5637 hsa-mir-32 Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5638 hsa-mir-100 Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5639 hsa-mir-143 Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5640 hsa-mir-145 Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5641 hsa-mir-146a Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5642 hsa-mir-191 Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5643 hsa-mir-199a-1 Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5644 hsa-mir-199a-2 Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5645 hsa-mir-218-1 Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5646 hsa-let-7c Prostatic Neoplasms 21880514 significantly changed during the progression of cancer 5647 hsa-mir-29a Leukemia, Myeloid, Acute 21880628 miR-29a and miR-30c might contribute to the sensitivity to cytarabine 5648 hsa-mir-30c-1 Leukemia, Myeloid, Acute 21880628 miR-29a and miR-30c might contribute to the sensitivity to cytarabine 5649 hsa-mir-30c-2 Leukemia, Myeloid, Acute 21880628 miR-29a and miR-30c might contribute to the sensitivity to cytarabine 5650 hsa-mir-637 Osteoporosis 21880893 miR-637 suppressed the growth of hMSCs and induced S-phase arrest. Expression of miR-637 was increased during adipocyte differentiation (AD) whereas it was decreased during osteoblast differentiation (OS), which suggests that miR-637 could act as a mediator of adipo-osteogenic differentiation. Disruption of this differentiation balance leads to various bone-related metabolic diseases, including osteoporosis. Therefore, miR-637 could contributes to osteoporosis. 5651 hsa-mir-155 Gastritis, Atrophic 21880981 MicroRNA-155 Is Essential for the T Cell-Mediated Control of Helicobacter pylori Infection and for the Induction of Chronic Gastritis and Colitis. 5652 hsa-mir-155 Colitis 21880981 MicroRNA-155 Is Essential for the T Cell-Mediated Control of Helicobacter pylori Infection and for the Induction of Chronic Gastritis and Colitis. 5653 hsa-mir-133a-1 Myocardial Infarction 21881276 The miR-133 levels in plasma from AMI patients exhibited a 4.4-fold increase compared with control subjects (p=0.006). Moreover, the increased miR-133 levels in whole blood were comparable with those in plasma samples. 5654 hsa-mir-133a-2 Myocardial Infarction 21881276 The miR-133 levels in plasma from AMI patients exhibited a 4.4-fold increase compared with control subjects (p=0.006). Moreover, the increased miR-133 levels in whole blood were comparable with those in plasma samples. 5655 hsa-mir-133b Myocardial Infarction 21881276 The miR-133 levels in plasma from AMI patients exhibited a 4.4-fold increase compared with control subjects (p=0.006). Moreover, the increased miR-133 levels in whole blood were comparable with those in plasma samples. 5656 hsa-mir-328 Myocardial Infarction 21881276 miR-328 levels in plasma and whole blood of AMI patients were markedly increased by 10.9-fold and 16.1-fold, respectively, compared to those in control subjects (p=0.033 and p<0.001). 5657 hsa-mir-31 Carcinoma, Squamous Cell 21882196 MiR-31 and miR-142-3p expression were correlated to histological differentiation in ESCC (P?60 years), males, nonsmokers, and Helicobacter pylori (H. pylori)-infected individuals (adjusted OR = 2.66, 95% CI: 1.38-5.13, P = 0.004; adjusted OR = 1.90, 95% CI: 1.10-3.27, P = 0.022; adjusted OR = 1.94, 95% CI: 1.12-3.35, P = 0.018; adjusted OR = 1.83, 95% CI: 1.08-3.10, P = 0.024, respectively). Further stratified analysis indicated that AA genotype facilitated developing of gastric cancer with lymph node metastasis (adjusted OR = 2.23, 95% CI: 1.07-4.64, P = 0.032). Expression analysis detected that rs928508 AA showed a significantly increased level of mature miR-30c compared with GG or AG/GG genotype (P = 0.011 or P = 0.013). Patients with AA genotype were associated with unfavorable outcome in overall survival compared with AG/GG genotype (Log rank 5.848, P = 0.016). This study demonstrates that pre-miR-30c A/G polymorphism may be associated with an increased risk of gastric cancer in a Chinese population through altering mature miR-30c expression. 6650 hsa-mir-30c-2 Stomach Neoplasms 22108846 The genotype frequencies of pre-miR-30c A/G (Polymorphism rs928508 in pre-miR-30c) in gastric cancer patients were obviously different from those in the controls (P = 0.022). AA genotype carriers were associated with an increased risk of gastric cancer compared with GG genotype (adjusted odds ratio (OR) = 1.83, 95% confidence interval (CI): 1.07-3.15, P = 0.029). Moreover, the gastric cancer risk especially elevated in older individuals (aged >60 years), males, nonsmokers, and Helicobacter pylori (H. pylori)-infected individuals (adjusted OR = 2.66, 95% CI: 1.38-5.13, P = 0.004; adjusted OR = 1.90, 95% CI: 1.10-3.27, P = 0.022; adjusted OR = 1.94, 95% CI: 1.12-3.35, P = 0.018; adjusted OR = 1.83, 95% CI: 1.08-3.10, P = 0.024, respectively). Further stratified analysis indicated that AA genotype facilitated developing of gastric cancer with lymph node metastasis (adjusted OR = 2.23, 95% CI: 1.07-4.64, P = 0.032). Expression analysis detected that rs928508 AA showed a significantly increased level of mature miR-30c compared with GG or AG/GG genotype (P = 0.011 or P = 0.013). Patients with AA genotype were associated with unfavorable outcome in overall survival compared with AG/GG genotype (Log rank 5.848, P = 0.016). This study demonstrates that pre-miR-30c A/G polymorphism may be associated with an increased risk of gastric cancer in a Chinese population through altering mature miR-30c expression. 6651 hsa-mir-23b Colonic Neoplasms 22109528 Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis. 6652 hsa-mir-206 Laryngeal Neoplasms 22110210 Down-regulation of MiR-206 Promotes Proliferation and Invasion of Laryngeal Cancer by Regulating VEGF Expression. 6653 hsa-mir-212 Carcinoma, Non-Small-Cell Lung 22110741 We identified histone modifications rather than DNA hypermethylation as epigenetic events that regulate miR-212 levels in NSCLC. Moreover, we found that miR-212 silencing in vivo is closely associated with the severity of the disease. 6654 hsa-mir-195 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6655 hsa-mir-146b Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6656 hsa-mir-26b Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6657 hsa-mir-374a Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6658 hsa-mir-374b Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6659 hsa-mir-199b Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6660 hsa-mir-132 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6661 hsa-mir-140 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6662 hsa-mir-487b Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6663 hsa-let-7g Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6664 hsa-mir-340 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6665 hsa-mir-155 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6666 hsa-mir-95 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6667 hsa-mir-186 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6668 hsa-mir-130a Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6669 hsa-mir-342 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6670 hsa-mir-577 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6671 hsa-mir-128-2 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6672 hsa-mir-146a Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6673 hsa-mir-16-1 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6674 hsa-mir-16-2 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6675 hsa-mir-503 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6676 hsa-mir-224 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6677 hsa-mir-223 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6678 hsa-mir-128-1 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6679 hsa-mir-181b-1 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6680 hsa-mir-181b-2 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6681 hsa-mir-1-1 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6682 hsa-mir-1-2 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6683 hsa-mir-421 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6684 hsa-mir-127 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6685 hsa-mir-34c Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6686 hsa-mir-497 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6687 hsa-mir-526a-1 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6688 hsa-mir-526a-2 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6689 hsa-mir-122 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6690 hsa-mir-518f Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6691 hsa-mir-591 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6692 hsa-mir-524 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6693 hsa-mir-320a Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6694 hsa-mir-520a Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6695 hsa-mir-183 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6696 hsa-mir-516a-1 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6697 hsa-mir-516a-2 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6698 hsa-mir-516b-1 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6699 hsa-mir-516b-2 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6700 hsa-mir-629 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6701 hsa-mir-595 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6702 hsa-mir-640 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6703 hsa-mir-520d Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6704 hsa-mir-519e Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6705 hsa-mir-363 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6706 hsa-mir-513a-1 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6707 hsa-mir-513a-2 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6708 hsa-mir-513b Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6709 hsa-mir-513c Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6710 hsa-mir-328 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6711 hsa-mir-519a-1 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6712 hsa-mir-519a-2 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6713 hsa-mir-185 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6714 hsa-mir-658 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6715 hsa-mir-517a Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6716 hsa-mir-515-1 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6717 hsa-mir-515-2 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6718 hsa-mir-519c Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6719 hsa-mir-661 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6720 hsa-mir-182 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6721 hsa-mir-206 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6722 hsa-mir-193b Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6723 hsa-mir-601 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance 6724 hsa-let-7f-1 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6725 hsa-let-7f-2 Stomach Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity 6726 hsa-mir-34b Breast Neoplasms 22113133 In this study, we identified one such estrogen down-regulated microRNA, miR-34b, as an onco-suppressor that targets cyclin D1 and JAG-1 (jagged 1) in a ER-positive/wild-type p53 breast cancer cell line (MCF-7) as well as in ovarian and endometrial cells, but not in ER-negative or mutant p53 breast cancer cell lines (T47D, MBA-MB-361 and MDA-MB-435). There is a negative association between ER and miR-34b expression levels in ER-positive breast cancer patients. Tet-on induction of miR-34b can cause inhibition of tumor growth and cell proliferation. Also, the overexpression of miR-34b inhibited ER-positive breast tumor growth in an orthotropic mammary fat pad xenograft mouse model. Further validations indicated that estrogen inhibition of miR-34b expression was mediated by interactions between ER and p53, not by DNA methylation regulation. The xenoestrogens diethylstilbestrol and zeranol also showed similar estrogenic effects by inhibiting miR-34b expression and by restoring the protein levels of miR-34b targets, cyclin D1 and JAG-1, in MCF-7 cells. 6727 hsa-mir-629 Lung Neoplasms 22114071 The rs2735383CC (NBS1 gene) genotype had a significantly increased risk of lung cancer under a recessive genetic model in the total 1559 cases versus 1679 controls (OR = 1.40, 95% C.I. = 1.18-1.66, P = 0.0001) when compared with GG or GC genotypes; the rs2735383CC genotype carriers had lower mRNA and protein expression levels in tumor tissues than those of other genotypes as qPCR and western blot shown. Luciferase assay revealed that the rs2735383C allele had a lower transcription activity than G allele; and the hsa-miR-629 but not hsa-miR-499-5P had effect on modulation of NBS1 gene in vitro. We further observed that the X-ray radiation induced more chromatid breaks in lymphocyte cells from the carriers of rs2735383CC homozygote than those from the subjects with other genotypes (P = 0.0008). Our data suggested that the rs2735383G>C variation contributes to an increased risk of lung cancer by diminishing gene's expression through binding of microRNA-629 to the polymorphic site in the 3'-UTR of NBS1 gene. 6728 hsa-mir-21 Pancreatic Neoplasms 22114136 In the initial cohort of 48 PDAC (pancreatic ductal adenocarcinoma) patients, high expression of miR-21 (Hazard ratio (HR): 3.22, 95% Confidence Interval (CI):1.21-8.58) and reduced expression of miR-34a (HR 0.15, 95%CI: 0.06-0.37) and miR-30d (HR:0.30, 95%CI:0.12-0.79) were associated with poor overall survival following resection independent of clinical covariates. In a further validation set of 24 patients miR-21 and miR-34a expression again significantly correlated with overall survival (P = 0.031 and P = 0.001). 6729 hsa-mir-34a Pancreatic Neoplasms 22114136 In the initial cohort of 48 PDAC (pancreatic ductal adenocarcinoma) patients, high expression of miR-21 (Hazard ratio (HR): 3.22, 95% Confidence Interval (CI):1.21-8.58) and reduced expression of miR-34a (HR 0.15, 95%CI: 0.06-0.37) and miR-30d (HR:0.30, 95%CI:0.12-0.79) were associated with poor overall survival following resection independent of clinical covariates. In a further validation set of 24 patients miR-21 and miR-34a expression again significantly correlated with overall survival (P = 0.031 and P = 0.001). 6730 hsa-mir-21 Pancreatic Neoplasms 22114139 altered expression 6731 hsa-mir-200a Pancreatic Neoplasms 22114139 altered expression 6732 hsa-mir-200b Pancreatic Neoplasms 22114139 altered expression 6733 hsa-mir-200c Pancreatic Neoplasms 22114139 altered expression 6734 hsa-mir-216a Pancreatic Neoplasms 22114139 altered expression 6735 hsa-mir-216b Pancreatic Neoplasms 22114139 altered expression 6736 hsa-mir-217 Pancreatic Neoplasms 22114139 altered expression 6737 hsa-mir-146a Pancreatic Neoplasms 22114139 altered expression 6738 hsa-mir-155 Pancreatic Neoplasms 22114139 altered expression 6739 hsa-mir-182 Pancreatic Neoplasms 22114139 altered expression 6740 hsa-mir-196b Pancreatic Neoplasms 22114139 altered expression 6741 hsa-mir-203 Pancreatic Neoplasms 22114139 altered expression 6742 hsa-mir-222 Pancreatic Neoplasms 22114139 altered expression 6743 hsa-mir-338 Pancreatic Neoplasms 22114139 miR-338-3p;altered expression 6744 hsa-mir-486 Pancreatic Neoplasms 22114139 miR-486-3p:altered expression 6745 hsa-mir-125b-1 Pancreatic Neoplasms 22114139 altered expression 6746 hsa-mir-125b-2 Pancreatic Neoplasms 22114139 altered expression 6747 hsa-mir-296 Pancreatic Neoplasms 22114139 miR-296-5p:altered expression 6748 hsa-mir-183 Pancreatic Neoplasms 22114139 miR-183*:altered expression 6749 hsa-mir-603 Pancreatic Neoplasms 22114139 altered expression 6750 hsa-mir-625 Pancreatic Neoplasms 22114139 miR-625*:altered expression 6751 hsa-mir-708 Pancreatic Neoplasms 22114139 altered expression 6752 hsa-mir-122 Hepatitis C 22114337 A high level of miR122 was expressed by lentiviral vector into human liver cell lines at a level comparable to the endogenous level in Huh7 cells. Among the cell lines we examined, Hep3B cells stably expressing miR122 (Hep3B/miR122) exhibited a significant enhancement of HCVcc propagation. Surprisingly, the productions of infectious particles in Hep3B/miR122 cells upon infection with HCVcc were comparable to those in Huh7 cells. Furthermore, a line of "cured" cells established by elimination of HCV RNA from the Hep3B/miR122 replicon cells exhibited an enhanced expression of miR122 and a continuous increase of infectious titers of HCVcc in every passage. 6753 hsa-mir-17 Lymphoma, Mantle-Cell 22116552 The miRNA-17-92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. 6754 hsa-mir-18a Lymphoma, Mantle-Cell 22116552 The miRNA-17-92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. 6755 hsa-mir-19a Lymphoma, Mantle-Cell 22116552 The miRNA-17-92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. 6756 hsa-mir-20a Lymphoma, Mantle-Cell 22116552 The miRNA-17-92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. 6757 hsa-mir-19b-1 Lymphoma, Mantle-Cell 22116552 The miRNA-17-92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. 6758 hsa-mir-92a-1 Lymphoma, Mantle-Cell 22116552 The miRNA-17-92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. 6759 hsa-mir-193a Carcinoma, Hepatocellular 22117060 DNA methylation regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via SRSF2. 6760 hsa-mir-10b Pancreatic Neoplasms 22117151 miR-10b is upregulated in pancreatic ductal adenocarcinoma and can be used as a diagnostic marker in endoscopic ultrasound-guided fine-needle aspiration biopsies of suspicious pancreatic lesions. In addition, miR-10b may be able to guide neoadjuvant gemcitabine-based chemoradiotherapy and predict metastatic-free survival and overall survival. 6761 hsa-mir-221 Prostatic Neoplasms 22117988 The level of ARHI mRNA was significantly lower in aggressive compared with non-aggressive prostate cancer tissue samples. In contrast, microRNA 221 and 222 levels were significantly higher in aggressive compared with non-aggressive prostate cancer tissue samples. 6762 hsa-mir-222 Prostatic Neoplasms 22117988 The level of ARHI mRNA was significantly lower in aggressive compared with non-aggressive prostate cancer tissue samples. In contrast, microRNA 221 and 222 levels were significantly higher in aggressive compared with non-aggressive prostate cancer tissue samples. 6763 hsa-mir-378a Myocytes, Cardiac 22119805 Overexpression of microRNA-378 attenuates ischemia-induced apoptosis by inhibiting caspase-3 expression in cardiac myocytes. 6764 hsa-mir-21 Colorectal Neoplasms 22120473 Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases. 6765 hsa-mir-135a-1 Colorectal Neoplasms 22120473 Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases. 6766 hsa-mir-135a-2 Colorectal Neoplasms 22120473 Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases. 6767 hsa-mir-335 Colorectal Neoplasms 22120473 Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases. 6768 hsa-mir-206 Colorectal Neoplasms 22120473 Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases. 6769 hsa-let-7a-1 Colorectal Neoplasms 22120473 Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases. 6770 hsa-let-7a-2 Colorectal Neoplasms 22120473 Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases. 6771 hsa-let-7a-3 Colorectal Neoplasms 22120473 Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases. 6772 hsa-mir-100 Lung Neoplasms 22120675 MiR-100 Resensitizes Docetaxel-Resistant Human Lung Adenocarcinoma Cells (SPC-A1) to Docetaxel by Targeting Plk1. 6773 hsa-mir-27b Neuroblastoma 22120719 MiR-27b targets PPARgamma to inhibit growth, tumor progression and the inflammatory response in neuroblastoma cells. 6774 hsa-mir-7-1 Glioma 22120825 The absence of miR-7 function could cause downstream molecules to switch on or off, resulting in glioma development, invasion, and metastases. MiR-7-based gene treatment may be a novel anti-invasion therapeutic strategy for malignant glioma. 6775 hsa-mir-7-2 Glioma 22120825 The absence of miR-7 function could cause downstream molecules to switch on or off, resulting in glioma development, invasion, and metastases. MiR-7-based gene treatment may be a novel anti-invasion therapeutic strategy for malignant glioma. 6776 hsa-mir-7-3 Glioma 22120825 The absence of miR-7 function could cause downstream molecules to switch on or off, resulting in glioma development, invasion, and metastases. MiR-7-based gene treatment may be a novel anti-invasion therapeutic strategy for malignant glioma. 6777 hsa-mir-423 Heart Failure 22120965 miR-423-5p: significantly increased serum level 6778 hsa-mir-320a Heart Failure 22120965 significantly increased serum level 6779 hsa-mir-22 Heart Failure 22120965 significantly increased serum level 6780 hsa-mir-92b Heart Failure 22120965 significantly increased serum level 6781 hsa-mir-1915 Colorectal Neoplasms 22121083 miR-1915 inhibits Bcl-2 to modulate multidrug resistance by increasing drug-sensitivity in human colorectal carcinoma cells. 6782 hsa-mir-124-1 Neuroblastoma 22123030 Ectopic overexpression of miR-124 resulted in the downregulation of CDK6, decreased cellular proliferation, and induced cellular morphological changes. 6783 hsa-mir-124-2 Neuroblastoma 22123030 Ectopic overexpression of miR-124 resulted in the downregulation of CDK6, decreased cellular proliferation, and induced cellular morphological changes. 6784 hsa-mir-124-3 Neuroblastoma 22123030 Ectopic overexpression of miR-124 resulted in the downregulation of CDK6, decreased cellular proliferation, and induced cellular morphological changes. 6785 hsa-mir-221 Colonic Neoplasms 22126772 MicroRNA-221 promotes colon carcinoma cell proliferation in vitro by inhibiting CDKN1C/p57 expression. 6786 hsa-mir-221 Prostatic Neoplasms 22127852 The altered expression of MiR-221/-222 (increased miR-221/-222 expression ) and MiR-23b/-27b (down-regulated ) is associated with the development of human castration resistant prostate cancer. 6787 hsa-mir-222 Prostatic Neoplasms 22127852 The altered expression of MiR-221/-222 (increased miR-221/-222 expression ) and MiR-23b/-27b (down-regulated ) is associated with the development of human castration resistant prostate cancer. 6788 hsa-mir-23b Prostatic Neoplasms 22127852 The altered expression of MiR-221/-222 (increased miR-221/-222 expression ) and MiR-23b/-27b (down-regulated ) is associated with the development of human castration resistant prostate cancer. 6789 hsa-mir-27b Prostatic Neoplasms 22127852 The altered expression of MiR-221/-222 (increased miR-221/-222 expression ) and MiR-23b/-27b (down-regulated ) is associated with the development of human castration resistant prostate cancer. 6790 hsa-let-7c Prostatic Neoplasms 22128178 MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cells. 6791 hsa-let-7a-1 Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6792 hsa-let-7a-2 Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6793 hsa-let-7a-3 Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6794 hsa-let-7c Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6795 hsa-mir-130a Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6796 hsa-mir-301a Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6797 hsa-mir-520d Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6798 hsa-mir-181b-1 Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6799 hsa-mir-181b-2 Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6800 hsa-mir-19b-1 Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6801 hsa-mir-19b-2 Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6802 hsa-mir-23a Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6803 hsa-mir-30a Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6804 hsa-mir-548a-1 Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6805 hsa-mir-548a-2 Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6806 hsa-mir-548a-3 Periodontitis 22128589 Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones. 6807 hsa-mir-206 Muscular Dystrophies 22129894 The expression of miR-206 is increased in muscular dystrophy. 6808 hsa-mir-21 Melanoma 22130252 Increased levels of microRNA-21 expression were shown from dysplastic nevi to primary cutaneous melanomas to melanoma metastases. Moreover, high miR-21 expression was found to be correlated with Breslow thickness and advanced clinical stage. Patients with high microRNA-21 expression showed shorter 5-year disease-free or overall survival than those with low microRNA-21 expression. Furthermore, multivariate regression analysis showed that the status of microRNA-21 expression was an independent prognostic factor for overall survival of patients. Antisense-mediated microRNA-21 inhibition could significantly suppress growth, increase apoptosis and enhance chemo- or radiosensitivity of human cutaneous melanoma cells by inducing the increased Bax/Bcl-2 ratio. Thus, the status of microRNA-21 might be an independent prognostic factor for patients with cutaneous melanoma, and microRNA-21 has the potential of being a novel molecular target for the treatment of human cutaneous melanoma. 6809 hsa-mir-9-1 Melanoma 22131135 MicroRNA-9 up-regulates E-cadherin through inhibition of NF-kB1-Snail1 pathway in melanoma. 6810 hsa-mir-184 Eye Abnormalities 22131394 Bi-directional sequencing identified a single-base substitution +57C>T in miR-184. This variation segregated with the disease phenotype and was absent in the 1000 Genomes project, 1130 control chromosomes, and 28 non-human vertebrates.Conclusion:The single-base pair substitution in the seed region of miR-184 is responsible for the disease phenotype observed in EDICT syndrome. 6811 hsa-mir-375 Mouth Neoplasms 22132151 MiR-375 is repressed and miR-127 activated in OSCC, and we confirm previous reports of miR-137 hypermethylation in oral cancer. The miR-200 s/miR-205 were epigenetically activated in tumors vs normal tissues, but repressed in the absence of DNA hypermethylation specifically in CD44(high) oral CSCs. Aberrant miR-375 and miR-200a expression and miR-200c-141 methylation could be detected in and distinguish OSCC patient oral rinse and saliva from healthy volunteers. 6812 hsa-mir-127 Mouth Neoplasms 22132151 MiR-375 is repressed and miR-127 activated in OSCC, and we confirm previous reports of miR-137 hypermethylation in oral cancer. The miR-200 s/miR-205 were epigenetically activated in tumors vs normal tissues, but repressed in the absence of DNA hypermethylation specifically in CD44(high) oral CSCs. Aberrant miR-375 and miR-200a expression and miR-200c-141 methylation could be detected in and distinguish OSCC patient oral rinse and saliva from healthy volunteers. 6813 hsa-mir-137 Mouth Neoplasms 22132151 MiR-375 is repressed and miR-127 activated in OSCC, and we confirm previous reports of miR-137 hypermethylation in oral cancer. The miR-200 s/miR-205 were epigenetically activated in tumors vs normal tissues, but repressed in the absence of DNA hypermethylation specifically in CD44(high) oral CSCs. Aberrant miR-375 and miR-200a expression and miR-200c-141 methylation could be detected in and distinguish OSCC patient oral rinse and saliva from healthy volunteers. 6814 hsa-mir-200a Mouth Neoplasms 22132151 MiR-375 is repressed and miR-127 activated in OSCC, and we confirm previous reports of miR-137 hypermethylation in oral cancer. The miR-200 s/miR-205 were epigenetically activated in tumors vs normal tissues, but repressed in the absence of DNA hypermethylation specifically in CD44(high) oral CSCs. Aberrant miR-375 and miR-200a expression and miR-200c-141 methylation could be detected in and distinguish OSCC patient oral rinse and saliva from healthy volunteers. 6815 hsa-mir-200c Mouth Neoplasms 22132151 MiR-375 is repressed and miR-127 activated in OSCC, and we confirm previous reports of miR-137 hypermethylation in oral cancer. The miR-200 s/miR-205 were epigenetically activated in tumors vs normal tissues, but repressed in the absence of DNA hypermethylation specifically in CD44(high) oral CSCs. Aberrant miR-375 and miR-200a expression and miR-200c-141 methylation could be detected in and distinguish OSCC patient oral rinse and saliva from healthy volunteers. 6816 hsa-mir-141 Mouth Neoplasms 22132151 MiR-375 is repressed and miR-127 activated in OSCC, and we confirm previous reports of miR-137 hypermethylation in oral cancer. The miR-200 s/miR-205 were epigenetically activated in tumors vs normal tissues, but repressed in the absence of DNA hypermethylation specifically in CD44(high) oral CSCs. Aberrant miR-375 and miR-200a expression and miR-200c-141 methylation could be detected in and distinguish OSCC patient oral rinse and saliva from healthy volunteers. 6817 hsa-mir-17 Colorectal Neoplasms 22132820 Up-regulated miR-17 promotes cell proliferation, tumor growth and cell cycle progression by targeting RND3 tumor suppressor gene in colorectal carcinoma. 6818 hsa-mir-330 Lung Neoplasms 22132977 Expression of miR-330 in various colon and lung cancer cell lines, as measured by QRT-PCR, varied five-fold between samples and correlated with in-vitro gemcitabine resistance (R = 0.82, p = 0.04). Exposure to gemcitabine also appeared to influence miR-330 levels in these cell lines. Furthermore, in our cell line panel, miR-330 expression negatively correlated with dCK mRNA expression (R = 0.74), suggesting a role of miR-330 in post-transcriptional regulation of dCK. 6819 hsa-mir-330 Colonic Neoplasms 22132977 Expression of miR-330 in various colon and lung cancer cell lines, as measured by QRT-PCR, varied five-fold between samples and correlated with in-vitro gemcitabine resistance (R = 0.82, p = 0.04). Exposure to gemcitabine also appeared to influence miR-330 levels in these cell lines. Furthermore, in our cell line panel, miR-330 expression negatively correlated with dCK mRNA expression (R = 0.74), suggesting a role of miR-330 in post-transcriptional regulation of dCK. 6820 hsa-mir-15a Leukemia, Lymphocytic, Chronic, B-Cell 22133358 miR-15a and miR-16-1 inhibit the proliferation of leukemic cells by down-regulating WT1 protein level. 6821 hsa-mir-15a Multiple Myeloma 22133358 miR-15a and miR-16-1 inhibit the proliferation of leukemic cells by down-regulating WT1 protein level. 6822 hsa-mir-15a Leukemia, Myeloid, Acute 22133358 miR-15a and miR-16-1 inhibit the proliferation of leukemic cells by down-regulating WT1 protein level. 6823 hsa-mir-1266 Psoriasis 22133505 Increased serum levels of miR-1266 in patients with psoriasis vulgaris. 6824 hsa-mir-9-1 Carcinoma, Squamous Cell 22133638 Methylation of microRNA-9 is a specific and sensitive biomarker for oral and oropharyngeal squamous cell carcinomas. 6825 hsa-mir-9-3 Carcinoma, Squamous Cell 22133638 Methylation of microRNA-9 is a specific and sensitive biomarker for oral and oropharyngeal squamous cell carcinomas. 6826 hsa-mir-21 Urinary Bladder Neoplasms 22133680 Nuclear and cytoplasmatic PDCD4 immunostaining decreased significantly with histopathological progression of the tumor (p<0001). Controls showed strong nuclear and cytoplasmatic immunohistochemical staining. MiR-21 up regulation in tissue corresponded to PDCD4 suppression. 6827 hsa-mir-320a Colorectal Neoplasms 22134529 microRNA-320a inhibits tumor invasion by targeting neuropilin 1 and is associated with liver metastasis in colorectal cancer. 6828 hsa-mir-182 Medulloblastoma 22134538 MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma. 6829 hsa-mir-23a Vascular Diseases 22136461 miRNA-23/27/24 cluster has potential therapetic application in vascular disorders and ischemic heart disease 6830 hsa-mir-27a Vascular Diseases 22136461 miRNA-23/27/24 cluster has potential therapetic application in vascular disorders and ischemic heart disease 6831 hsa-mir-24-2 Vascular Diseases 22136461 miRNA-23/27/24 cluster has potential therapetic application in vascular disorders and ischemic heart disease 6832 hsa-mir-23a Heart Diseases 22136461 miRNA-23/27/24 cluster has potential therapetic application in vascular disorders and ischemic heart disease 6833 hsa-mir-27a Heart Diseases 22136461 miRNA-23/27/24 cluster has potential therapetic application in vascular disorders and ischemic heart disease 6834 hsa-mir-24-2 Heart Diseases 22136461 miRNA-23/27/24 cluster has potential therapetic application in vascular disorders and ischemic heart disease 6835 hsa-mir-135a-1 Glioma 22139076 MiR-135a functions as a selective killer of malignant glioma. 6836 hsa-mir-135a-2 Glioma 22139076 MiR-135a functions as a selective killer of malignant glioma. 6837 hsa-mir-7-1 Stomach Neoplasms 22139078 Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells. 6838 hsa-mir-7-2 Stomach Neoplasms 22139078 Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells. 6839 hsa-mir-7-3 Stomach Neoplasms 22139078 Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells. 6840 hsa-mir-24-1 Laryngeal Neoplasms 22139384 miR-24 functions as a tumor suppressor in Hep2 laryngeal carcinoma cells partly through down-regulation of the S100A8 protein. 6841 hsa-mir-24-2 Laryngeal Neoplasms 22139384 miR-24 functions as a tumor suppressor in Hep2 laryngeal carcinoma cells partly through down-regulation of the S100A8 protein. 6842 hsa-mir-146a Lichen Planus, Oral 22139425 Increased miRNA-146a and miRNA-155 expressions in oral lichen planus. 6843 hsa-mir-155 Lichen Planus, Oral 22139425 Increased miRNA-146a and miRNA-155 expressions in oral lichen planus. 6844 hsa-mir-30c-1 Endometrial Neoplasms 22139444 Endometrial Neoplasms 6845 hsa-mir-30c-2 Endometrial Neoplasms 22139444 Endometrial Neoplasms 6846 hsa-mir-200b Lung Neoplasms 22139708 MicroRNA-200b reverses chemoresistance of docetaxel-resistant human lung adenocarcinoma cells by targeting E2F3. 6847 hsa-mir-125b-1 Leukemia, B-Cell 22139839 MiR-125b and miR-155 contribute to BCL2 repression and proliferation in response to CD40 ligand (CD154) in human leukemic B-cells. 6848 hsa-mir-125b-2 Leukemia, B-Cell 22139839 MiR-125b and miR-155 contribute to BCL2 repression and proliferation in response to CD40 ligand (CD154) in human leukemic B-cells. 6849 hsa-mir-155 Leukemia, B-Cell 22139839 MiR-125b and miR-155 contribute to BCL2 repression and proliferation in response to CD40 ligand (CD154) in human leukemic B-cells. 6850 hsa-mir-122 Carcinoma, Hepatocellular 22140464 miR-122 expression is highly elevated in quiescent human primary hepatocytes (hPHs) but lost or attenuated in hESCs and HCCs, while an opposing expression pattern is observed for Pkm2. Depleting hESCs and HCCs of Pkm2, or overexpressing miR-122, leads to a common deficiency in self-renewal and proliferation. 6851 hsa-mir-182 Urinary Bladder Neoplasms 22140553 deregulated 6852 hsa-mir-183 Urinary Bladder Neoplasms 22140553 deregulated 6853 hsa-mir-10a Urinary Bladder Neoplasms 22140553 deregulated 6854 hsa-mir-203 Urinary Bladder Neoplasms 22140553 deregulated 6855 hsa-mir-224 Urinary Bladder Neoplasms 22140553 deregulated 6856 hsa-mir-1-1 Urinary Bladder Neoplasms 22140553 deregulated 6857 hsa-mir-1-2 Urinary Bladder Neoplasms 22140553 deregulated 6858 hsa-mir-143 Urinary Bladder Neoplasms 22140553 deregulated 6859 hsa-mir-145 Urinary Bladder Neoplasms 22140553 deregulated 6860 hsa-mir-133a-1 Urinary Bladder Neoplasms 22140553 deregulated 6861 hsa-mir-133a-2 Urinary Bladder Neoplasms 22140553 deregulated 6862 hsa-mir-133b Urinary Bladder Neoplasms 22140553 deregulated 6863 hsa-mir-125b-1 Urinary Bladder Neoplasms 22140553 deregulated 6864 hsa-mir-125b-2 Urinary Bladder Neoplasms 22140553 deregulated 6865 hsa-mir-210 Carcinoma, Hepatocellular 22144109 Hypoxia-inducible MicroRNA-210 augments the metastatic potential of tumor cells by targeting vacuole membrane protein 1 in hepatocellular carcinoma. 6866 hsa-mir-200c Breast Neoplasms 22144583 MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F. 6867 hsa-mir-223 Lymphoproliferative Disorders 22145958 microRNA-223 expression is uniformly down-regulated in B cell lymphoproliferative disorders and is associated with poor survival in chronic lymphocytic leukemia patients. 6868 hsa-mir-223 Leukemia, Lymphocytic, Chronic, B-Cell 22145958 microRNA-223 expression is uniformly down-regulated in B cell lymphoproliferative disorders and is associated with poor survival in chronic lymphocytic leukemia patients. 6869 hsa-mir-421 Biliary Tract Neoplasms 22146319 MicroRNA-421 functions as an oncogenic miRNA in biliary tract cancer through down-regulating farnesoid X receptor expression. 6870 hsa-mir-23b Pain 22149086 MiR23b Ameliorates Neuropathic Pain in Spinal Cord by Silencing NOX4. 6871 hsa-mir-494 Lung Neoplasms 22151897 MicroRNA-494 suppresses cell proliferation and induces senescence in A549 lung cancer cells. 6872 hsa-mir-221 Carcinoma, Hepatocellular 22152314 MiR-221 contributes to the growth of hepatocellular carcinoma cells and miR-221 inhibition can induce cell apoptosis. miR-221 has the potential to become one of the new molecular targets for liver cancer therapy. 6873 hsa-mir-92a-1 Myocardial Infarction 22153007 In STEMI (ST-segment elevation myocardial infarction) patients, the expression of circulating miR-92a is up-regulated. PCI therapy may suppress such up-regulation. Survival rate is higher in patients showing down-regulation of miR-92a. Our data suggest that miR-92a might have potential for diagnosis and therapeutic application in the prevention and treatment of STEMI. 6874 hsa-mir-92a-2 Myocardial Infarction 22153007 In STEMI (ST-segment elevation myocardial infarction) patients, the expression of circulating miR-92a is up-regulated. PCI therapy may suppress such up-regulation. Survival rate is higher in patients showing down-regulation of miR-92a. Our data suggest that miR-92a might have potential for diagnosis and therapeutic application in the prevention and treatment of STEMI. 6875 hsa-mir-137 Alzheimer Disease 22155483 Blood serum expressio level of these miRNAs may be non-invasive biomarkers for Alzheimer's disease. 6876 hsa-mir-181c Alzheimer Disease 22155483 Blood serum expressio level of these miRNAs may be non-invasive biomarkers for Alzheimer's disease. 6877 hsa-mir-9-1 Alzheimer Disease 22155483 Blood serum expressio level of these miRNAs may be non-invasive biomarkers for Alzheimer's disease. 6878 hsa-mir-9-2 Alzheimer Disease 22155483 Blood serum expressio level of these miRNAs may be non-invasive biomarkers for Alzheimer's disease. 6879 hsa-mir-9-3 Alzheimer Disease 22155483 Blood serum expressio level of these miRNAs may be non-invasive biomarkers for Alzheimer's disease. 6880 hsa-mir-29a Alzheimer Disease 22155483 Blood serum expressio level of these miRNAs may be non-invasive biomarkers for Alzheimer's disease. 6881 hsa-mir-29b-1 Alzheimer Disease 22155483 Blood serum expressio level of these miRNAs may be non-invasive biomarkers for Alzheimer's disease. 6882 hsa-mir-29b-2 Alzheimer Disease 22155483 Blood serum expressio level of these miRNAs may be non-invasive biomarkers for Alzheimer's disease. 6883 hsa-mir-30e Glioma 22156201 MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop. 6884 hsa-mir-221 Breast Neoplasms 22156446 The expression level of miR-221 was significantly associated with hormone receptor (HR) status (p = 0.008). Patients with higher plasma miR-221 levels tended to be HR-negative. Patients with different miR-221 levels had significant differences in the overall response rate (p = 0.044) but not in the pathologic complete response rate (p = 0.477). 6885 hsa-mir-30b Lung Neoplasms 22157681 Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC). 6886 hsa-mir-221 Lung Neoplasms 22157681 Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC). 6887 hsa-mir-222 Lung Neoplasms 22157681 Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC). 6888 hsa-mir-203 Lung Neoplasms 22157681 Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC). 6889 hsa-mir-103a-1 Lung Neoplasms 22157681 Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC). 6890 hsa-mir-103b-1 Lung Neoplasms 22157681 Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC). 6891 hsa-mir-103a-2 Lung Neoplasms 22157681 Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC). 6892 hsa-mir-103b-2 Lung Neoplasms 22157681 Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC). 6893 hsa-mir-30c-1 Lung Neoplasms 22157681 Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC). 6894 hsa-mir-30c-2 Lung Neoplasms 22157681 Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC). 6895 hsa-mir-30a Breast Neoplasms 22157765 MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagy. 6896 hsa-mir-30a Ovarian Neoplasms 22157765 MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagy. 6897 hsa-mir-30a Carcinoma, Hepatocellular 22157765 MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagy. 6898 hsa-mir-107 Head and Neck Neoplasms 22158047 microRNA-107 functions as a candidate tumor-suppressor gene in head and neck squamous cell carcinoma by downregulation of protein kinase C? 6899 hsa-mir-520a Breast Neoplasms 22158050 MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kB and TGF-beta signaling pathways. 6900 hsa-mir-520b Breast Neoplasms 22158050 MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kB and TGF-beta signaling pathways. 6901 hsa-mir-520c Breast Neoplasms 22158050 MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kB and TGF-beta signaling pathways. 6902 hsa-mir-520d Breast Neoplasms 22158050 MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kB and TGF-beta signaling pathways. 6903 hsa-mir-373 Breast Neoplasms 22158050 MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kB and TGF-beta signaling pathways. 6904 hsa-mir-1245b Breast Neoplasms 22158906 Upregulation of miR-1245 by c-myc targets BRCA2 and impairs DNA repair. 6905 hsa-mir-1245a Breast Neoplasms 22158906 Upregulation of miR-1245 by c-myc targets BRCA2 and impairs DNA repair. 6906 hsa-mir-34a Carcinoma, Renal Cell 22159222 MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma. 6907 hsa-mir-205 Glioblastoma 22159356 MicroRNA-205 functions as a tumor suppressor in human glioblastoma cells by targeting VEGF-A. 6908 hsa-mir-1301 Carcinoma, Hepatocellular 22159405 microRNA-1301-mediated inhibition of tumorigenesis. 6909 hsa-mir-196a-2 Coronary Artery Disease 22159951 The variant genotypes CC/CT of hsa-mir-196a2 rs11614913 T ↿C were not associated with a significantly increased risk of CAD (adjusted OR = 1.02, 95% CI = 0.76-1.38), compared with wide genotype TT, but CC and CC/CT genotypes were associated with 34 and 35% increased risks of serious prognosis of CAD (adjusted HR = 1.34, 95% CI = 1.02-1.75 for CC; adjusted HR = 1.35, 95% CI = 1.03-1.75 for CC/CT). In the variant of hsa-mir-499 rs3746444A ↿G, GG was associated with the 223% increased risk of CAD (adjusted OR = 3.23, 95% CI = 1.56-6.67). Cox regression analysis showed that age, smoking status, numbers of pathological changes in coronary arteries, rs11614913 T ↿C, and diabetes mellitus were associated with serious prognosis of CAD. 6910 hsa-mir-499a Coronary Artery Disease 22159951 The variant genotypes CC/CT of hsa-mir-196a2 rs11614913 T ↿C were not associated with a significantly increased risk of CAD (adjusted OR = 1.02, 95% CI = 0.76-1.38), compared with wide genotype TT, but CC and CC/CT genotypes were associated with 34 and 35% increased risks of serious prognosis of CAD (adjusted HR = 1.34, 95% CI = 1.02-1.75 for CC; adjusted HR = 1.35, 95% CI = 1.03-1.75 for CC/CT). In the variant of hsa-mir-499 rs3746444A ↿G, GG was associated with the 223% increased risk of CAD (adjusted OR = 3.23, 95% CI = 1.56-6.67). Cox regression analysis showed that age, smoking status, numbers of pathological changes in coronary arteries, rs11614913 T ↿C, and diabetes mellitus were associated with serious prognosis of CAD. 6911 hsa-mir-96 Carcinoma, Hepatocellular 22160187 Suppression of microRNA-96 expression inhibits the invasion of hepatocellular carcinoma cells. 6912 hsa-mir-143 Uterine Cervical Neoplasms 22160209 miR-143 is downregulated in cervical cancer and promotes apoptosis and inhibits tumor formation by targeting Bcl-2. 6913 hsa-mir-17 Hypertension 22161164 Inhibition of microRNA-17 Improves Lung and Heart Function in Experimental Pulmonary Hypertension. 6914 hsa-mir-34a Arthritis, Rheumatoid 22161761 Downregulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance. 6915 hsa-mir-196a-2 Colorectal Neoplasms 22161766 The authors found a significantly increased colorectal cancer risk with the miR-196a2CC (rs11614913) genotype compared with the TT/CT genotype (AOR?=?1.50; 95% CI?=?1.11-2.04; P?=?0.01; FDR-P?=?0.04) in Korean population. 6916 hsa-mir-146a Prostatic Neoplasms 22161865 MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castration-resistant prostate cancer. 6917 hsa-mir-200a Prostatic Neoplasms 22161972 miR-200a overexpression reduced prostate cancer cell growth and may have potential, in combination with other markers, in stratifying prostate cancer patients for more intensive monitoring and therapy. 6918 hsa-mir-1-1 Heart Failure 22163007 MicroRNA-1 and -133 Increase Arrhythmogenesis in Heart Failure by Dissociating Phosphatase Activity from RyR2 Complex. 6919 hsa-mir-1-2 Heart Failure 22163007 MicroRNA-1 and -133 Increase Arrhythmogenesis in Heart Failure by Dissociating Phosphatase Activity from RyR2 Complex. 6920 hsa-mir-133a-1 Heart Failure 22163007 MicroRNA-1 and -133 Increase Arrhythmogenesis in Heart Failure by Dissociating Phosphatase Activity from RyR2 Complex. 6921 hsa-mir-133a-2 Heart Failure 22163007 MicroRNA-1 and -133 Increase Arrhythmogenesis in Heart Failure by Dissociating Phosphatase Activity from RyR2 Complex. 6922 hsa-mir-133b Heart Failure 22163007 MicroRNA-1 and -133 Increase Arrhythmogenesis in Heart Failure by Dissociating Phosphatase Activity from RyR2 Complex. 6923 hsa-mir-29a Biliary Atresia 22167021 MicroRNA Profiling Identifies miR-29 as a Regulator of Disease-Associated Pathways in Experimental Biliary Atresia. 6924 hsa-mir-29b-1 Biliary Atresia 22167021 MicroRNA Profiling Identifies miR-29 as a Regulator of Disease-Associated Pathways in Experimental Biliary Atresia. 6925 hsa-mir-146a Carcinoma, Hepatocellular 22167321 The authors demonstrate that miR-146a, miR-99b and miR-205, induced in HCC1937 BRCA1-expressing cells, bind and regulate TRAF2 gene. In addition, re-expression of miR-146a, miR-99b or miR-205 in HCC1937 BRCA1-null cells was sufficient to modulate NF-κB activity. 6926 hsa-mir-99b Carcinoma, Hepatocellular 22167321 The authors demonstrate that miR-146a, miR-99b and miR-205, induced in HCC1937 BRCA1-expressing cells, bind and regulate TRAF2 gene. In addition, re-expression of miR-146a, miR-99b or miR-205 in HCC1937 BRCA1-null cells was sufficient to modulate NF-κB activity. 6927 hsa-mir-205 Carcinoma, Hepatocellular 22167321 The authors demonstrate that miR-146a, miR-99b and miR-205, induced in HCC1937 BRCA1-expressing cells, bind and regulate TRAF2 gene. In addition, re-expression of miR-146a, miR-99b or miR-205 in HCC1937 BRCA1-null cells was sufficient to modulate NF-κB activity. 6928 hsa-mir-148a Stomach Neoplasms 22167392 MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in gastric cancer. 6929 hsa-mir-187 Stomach Neoplasms 22169097 Genome-wide miRNA expression profiles followed with Real-Time quantitative RT-PCR (qRT-PCR) assays revealed that miR-187(*), miR-371-5p and miR-378 were significantly elevated in GC patients. Further validation indicated that miR-378 alone could yields a ROC curve area of 0.861 with 87.5% sensitivity and 70.73% specificity in discriminating GC patients from healthy controls. 6930 hsa-mir-371a Stomach Neoplasms 22169097 Genome-wide miRNA expression profiles followed with Real-Time quantitative RT-PCR (qRT-PCR) assays revealed that miR-187(*), miR-371-5p and miR-378 were significantly elevated in GC patients. Further validation indicated that miR-378 alone could yields a ROC curve area of 0.861 with 87.5% sensitivity and 70.73% specificity in discriminating GC patients from healthy controls. 6931 hsa-mir-378a Stomach Neoplasms 22169097 Genome-wide miRNA expression profiles followed with Real-Time quantitative RT-PCR (qRT-PCR) assays revealed that miR-187(*), miR-371-5p and miR-378 were significantly elevated in GC patients. Further validation indicated that miR-378 alone could yields a ROC curve area of 0.861 with 87.5% sensitivity and 70.73% specificity in discriminating GC patients from healthy controls. 6932 hsa-mir-155 Inflammation 22170100 Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*. 6933 hsa-mir-375 Small Cell Lung Carcinoma 22172490 miR-375 is highly expressed and possibly transactivated by achaete-scute complex homolog 1 in small-cell lung cancer cells. 6934 hsa-mir-335 Glioma 22172575 MiR-335 is Required for Differentiation of Malignant Glioma Cells Induced by Activation of cAMP/PKA Pathway. 6935 hsa-mir-1183 Rectal Neoplasms 22172905 Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909?, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases. 6936 hsa-mir-483 Rectal Neoplasms 22172905 Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909?, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases. 6937 hsa-mir-622 Rectal Neoplasms 22172905 Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909?, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases. 6938 hsa-mir-125a Rectal Neoplasms 22172905 Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909?, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases. 6939 hsa-mir-1224 Rectal Neoplasms 22172905 Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909?, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases. 6940 hsa-mir-188 Rectal Neoplasms 22172905 Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909?, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases. 6941 hsa-mir-1471 Rectal Neoplasms 22172905 Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909?, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases. 6942 hsa-mir-671 Rectal Neoplasms 22172905 Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909?, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases. 6943 hsa-mir-1909 Rectal Neoplasms 22172905 Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909?, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases. 6944 hsa-mir-630 Rectal Neoplasms 22172905 Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909?, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases. 6945 hsa-mir-765 Rectal Neoplasms 22172905 Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909?, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases. 6946 hsa-mir-720 Rectal Neoplasms 22172905 Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909?, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases. 6947 hsa-mir-122 Carcinoma, Hepatocellular 22174818 Although miR-222, miR-223 or miR-21 were significantly up- or down-regulated between HCC patients and healthy controls, no significant difference was observed in the levels of these miRNAs between HBV patients without and with HCC. MiR-122 in serum was significantly higher in HCC patients than healthy controls (p<0.001). More importantly, it was found that the levels of miR-122 were significantly reduced in the post-operative serum samples when compared to the pre-operative samples. Although serum miR-122 was also elevated in HBV patients with HCC comparing with those without HCC, the difference was at the border line (p?=?0.043). 6948 hsa-mir-21 Carcinoma, Hepatocellular 22174818 Although miR-222, miR-223 or miR-21 were significantly up- or down-regulated between HCC patients and healthy controls, no significant difference was observed in the levels of these miRNAs between HBV patients without and with HCC. MiR-122 in serum was significantly higher in HCC patients than healthy controls (p<0.001). More importantly, it was found that the levels of miR-122 were significantly reduced in the post-operative serum samples when compared to the pre-operative samples. Although serum miR-122 was also elevated in HBV patients with HCC comparing with those without HCC, the difference was at the border line (p?=?0.043). 6949 hsa-mir-222 Carcinoma, Hepatocellular 22174818 Although miR-222, miR-223 or miR-21 were significantly up- or down-regulated between HCC patients and healthy controls, no significant difference was observed in the levels of these miRNAs between HBV patients without and with HCC. MiR-122 in serum was significantly higher in HCC patients than healthy controls (p<0.001). More importantly, it was found that the levels of miR-122 were significantly reduced in the post-operative serum samples when compared to the pre-operative samples. Although serum miR-122 was also elevated in HBV patients with HCC comparing with those without HCC, the difference was at the border line (p?=?0.043). 6950 hsa-mir-223 Carcinoma, Hepatocellular 22174818 Although miR-222, miR-223 or miR-21 were significantly up- or down-regulated between HCC patients and healthy controls, no significant difference was observed in the levels of these miRNAs between HBV patients without and with HCC. MiR-122 in serum was significantly higher in HCC patients than healthy controls (p<0.001). More importantly, it was found that the levels of miR-122 were significantly reduced in the post-operative serum samples when compared to the pre-operative samples. Although serum miR-122 was also elevated in HBV patients with HCC comparing with those without HCC, the difference was at the border line (p?=?0.043). 6951 hsa-mir-21 Ovarian Neoplasms 22176994 miR-21 might play an important role in the proliferation and apoptosis of ovarian epithelial carcinoma cells through negatively control the expression of PDCD4. 6952 hsa-mir-1-1 Urinary Bladder Neoplasms 22178073 Tumor suppressive microRNA-1 mediated novel apoptosis pathways through direct inhibition of splicing factor serine/arginine-rich 9 (SRSF9/SRp30c) in bladder cancer. 6953 hsa-mir-1-2 Urinary Bladder Neoplasms 22178073 Tumor suppressive microRNA-1 mediated novel apoptosis pathways through direct inhibition of splicing factor serine/arginine-rich 9 (SRSF9/SRp30c) in bladder cancer. 6954 hsa-mir-224 Carcinoma, Hepatocellular 22178270 Transcriptional regulation of mir-224 upregulated in human HCCs by NFkB inflammatory pathways. 6955 hsa-mir-124-1 Alzheimer Disease 22178568 The miR-124 regulates the expression of BACE1/-secretase correlated with cell death in Alzheimer's disease. 6956 hsa-mir-124-2 Alzheimer Disease 22178568 The miR-124 regulates the expression of BACE1/-secretase correlated with cell death in Alzheimer's disease. 6957 hsa-mir-124-3 Alzheimer Disease 22178568 The miR-124 regulates the expression of BACE1/-secretase correlated with cell death in Alzheimer's disease. 6958 hsa-mir-320a Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. 6959 hsa-mir-320b-1 Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. 6960 hsa-mir-320b-2 Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. 6961 hsa-mir-320c-1 Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. 6962 hsa-mir-320c-2 Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. 6963 hsa-mir-320d-1 Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. 6964 hsa-mir-320d-2 Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. 6965 hsa-mir-320e Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. 6966 hsa-mir-451a Glioma 22179124 MicroRNA miR-451 downregulates the PI3K/AKT pathway through CAB39 in human glioma. 6967 hsa-mir-574 Urinary Bladder Neoplasms 22179486 Novel oncogenic function of mesoderm development candidate 1 and its regulation by MiR-574-3p in bladder cancer cell lines. 6968 hsa-mir-1-1 Colonic Neoplasms 22179665 MIR-1 DOWNREGULATION COOPERATES WITH MACC1 IN PROMOTING MET OVEREXPRESSION IN HUMAN COLON CANCER. 6969 hsa-mir-409 Stomach Neoplasms 22179828 MicroRNA-409 suppresses tumour cell invasion and metastasis by directly targeting radixin in gastric cancers. 6970 hsa-mir-133b Uterine Cervical Neoplasms 22179829 MicroRNA-133b is a key promoter of cervical carcinoma development through the activation of the ERK and AKT1 pathways. 6971 hsa-mir-146a Carcinoma, Squamous Cell 22182931 This study identifies that areca nut extract, TNFalpha and TGFbeta up-regulates miR-146a in OSCC cells. The increased expression of miR-146a enhanced the oncogenicity of OSCC cells. In addition, a G to C polymorphism (rs2910164), which is located in the pre-miR-146a and has been associated with functional alterations in miR-146a, was significantly more prevalent among OSCC patients having more advanced nodal involvement. Our analysis also suggested a higher miR-146a expression in OSCC tissues of patients carrying C polymorphism. The present study concluded a higher prevalence of the pre-mir-146a C-variant was associated with OSCC progression in patients with this disease. 6972 hsa-mir-137 Schizophrenia 22182936 Schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 are miR-137 targets. 6973 hsa-mir-155 Down Syndrome 22182977 a screening of micro-RNA (miRNA) from Down's syndrome brain and peripheral tissues indicated an upregulation of a chromosome 21-encoded miRNA-155 and a decrease in the abundance of the miRNA-155 mRNA target complement factor H (CFH), an important repressor of the innate immune response. 6974 hsa-mir-200a Lymphoma 22183793 MicroRNA-200 is commonly repressed in conjunctival MALT lymphoma, and targets cyclin E2. 6975 hsa-mir-200b Lymphoma 22183793 MicroRNA-200 is commonly repressed in conjunctival MALT lymphoma, and targets cyclin E2. 6976 hsa-mir-200c Lymphoma 22183793 MicroRNA-200 is commonly repressed in conjunctival MALT lymphoma, and targets cyclin E2. 6977 hsa-mir-7-1 Rhinitis, Allergic, Perennial 22185732 up-regulated 6978 hsa-mir-7-2 Rhinitis, Allergic, Perennial 22185732 up-regulated 6979 hsa-mir-7-3 Rhinitis, Allergic, Perennial 22185732 up-regulated 6980 hsa-mir-498 Rhinitis, Allergic, Perennial 22185732 down-regulated 6981 hsa-mir-187 Rhinitis, Allergic, Perennial 22185732 down-regulated 6982 hsa-mir-874 Rhinitis, Allergic, Perennial 22185732 down-regulated 6983 hsa-mir-143 Rhinitis, Allergic, Perennial 22185732 down-regulated 6984 hsa-mir-224 Rhinitis, Allergic, Perennial 22185732 down-regulated 6985 hsa-mir-767 Rhinitis, Allergic, Perennial 22185732 miR-767-5p: down-regulated 6986 hsa-mir-365a Lung Neoplasms 22185756 MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1. 6987 hsa-mir-365b Lung Neoplasms 22185756 MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1. 6988 hsa-mir-20a Osteosarcoma 22186140 miR-20a increases the metastatic potential of osteosarcoma cells by regulating Fas expression. 6989 hsa-mir-21 Breast Neoplasms 22187223 Re-expression of miR-21 contributes to migration and invasion by inducing epithelial-mesenchymal transition consistent with cancer stem cell characteristics in MCF-7 cells. 6990 hsa-mir-24-1 Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 6991 hsa-mir-24-2 Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 6992 hsa-mir-26a-1 Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 6993 hsa-mir-26a-2 Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 6994 hsa-mir-181a-1 Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 6995 hsa-mir-181a-2 Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 6996 hsa-mir-342 Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 6997 hsa-mir-574 Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 6998 hsa-mir-130b Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 6999 hsa-mir-103a-1 Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 7000 hsa-mir-103b-1 Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 7001 hsa-mir-103a-2 Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 7002 hsa-mir-103b-2 Pre-Eclampsia 22187671 Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis. 7003 hsa-mir-610 Stomach Neoplasms 22189055 MicroRNA-610 inhibits the migration and invasion of gastric cancer cells by suppressing the expression of vasodilator-stimulated phosphoprotein. 7004 hsa-mir-122 Hepatitis C 22189820 Here we show that HCV IRES-dependent translation efficiency in the hepatoma cell line Huh7 is highest during the G 0 and G 1 phases of the cell cycle but significantly drops during the S phase and even more in the G 2/M phase. The superimposed stimulation of HCV translation by ectopic miR-122 works best during the G 0, G 1 and G 2/M phases but is lower during the S phase. However, the levels of Ago2 protein do not substantially change during cell cycle phases, indicating that other cellular factors involved in HCV translation stimulation by miR-122 may be differentially expressed in different cell cycle phases. Moreover, the levels of endogenously expressed miR-122 in Huh7 cells are lowest in the S phase, indicating that the predominant G 0/G 1 state of non-dividing hepatocytes in the liver facilitates high expression of the HCV genome and stimulation by miR-122, with yet unknown factors involved in the differential extent of stimulation by miR-122. 7005 hsa-mir-570 Stomach Neoplasms 22190470 A guanine-to-cytosine mutation at the 3'-UTR of CD274 mRNA led to CD274 over-expression by disrupting the miR-570 binding. A frequent somatic mutation in CD274 3'-UTR leads to protein over-expression in gastric cancer by disrupting miR-570 binding. 7006 hsa-mir-21 Uterine Cervical Neoplasms 22194833 mir-21 expression increased with worsening clinical diagnosis but that mir-143 was not correlated with histology. These observations were in stark contrast to previous reports involving cervical cancer cell lines in which mir-143 was consistently down-regulated but mir-21 largely unaffected. 7007 hsa-mir-143 Uterine Cervical Neoplasms 22194833 mir-21 expression increased with worsening clinical diagnosis but that mir-143 was not correlated with histology. These observations were in stark contrast to previous reports involving cervical cancer cell lines in which mir-143 was consistently down-regulated but mir-21 largely unaffected. 7008 hsa-mir-200b Endometrial Neoplasms 22194984 Luciferase assays and Western blot analysis demonstrated that the miR-200b/200c/429 family recognized the MRE in the 3' UTR of AP-2α gene and negatively regulated the expression of endogenous AP-2α proteins. SNP rs1045385 A>C variation enhanced AP-2α expression by disrupting the binding of the miR-200b/200c/429 family to the 3' UTR of AP-2α. The effects of the two polymorphic variants on cisplatin sensitivity were determined by clonogenic assay. The overexpression of AP-2α with mutant 3' UTR (C allele) in the endometrial cancer cell line HEC-1A, which has high levels of endogenous miR-200b/200c/429 and low levels of AP-2α protein, significantly increased cisplatin sensitivity, but overexpression of A allele of AP-2α has no significant effects, compared with mock transfection. We concluded that miR-200b/200c/429 induced cisplatin resistance by repressing AP-2α expression in endometrial cancer cells. The SNP (rs1045385) A>C variation decreased the binding of miR-200b/200c/429 to the 3' UTR of AP-2α, which upregulated AP-2α protein expression and increased cisplatin sensitivity. Our results suggest that SNP (rs1045385) may be a potential prognostic marker for cisplatin treatment. 7009 hsa-mir-200c Endometrial Neoplasms 22194984 Luciferase assays and Western blot analysis demonstrated that the miR-200b/200c/429 family recognized the MRE in the 3' UTR of AP-2α gene and negatively regulated the expression of endogenous AP-2α proteins. SNP rs1045385 A>C variation enhanced AP-2α expression by disrupting the binding of the miR-200b/200c/429 family to the 3' UTR of AP-2α. The effects of the two polymorphic variants on cisplatin sensitivity were determined by clonogenic assay. The overexpression of AP-2α with mutant 3' UTR (C allele) in the endometrial cancer cell line HEC-1A, which has high levels of endogenous miR-200b/200c/429 and low levels of AP-2α protein, significantly increased cisplatin sensitivity, but overexpression of A allele of AP-2α has no significant effects, compared with mock transfection. We concluded that miR-200b/200c/429 induced cisplatin resistance by repressing AP-2α expression in endometrial cancer cells. The SNP (rs1045385) A>C variation decreased the binding of miR-200b/200c/429 to the 3' UTR of AP-2α, which upregulated AP-2α protein expression and increased cisplatin sensitivity. Our results suggest that SNP (rs1045385) may be a potential prognostic marker for cisplatin treatment. 7010 hsa-mir-429 Endometrial Neoplasms 22194984 Luciferase assays and Western blot analysis demonstrated that the miR-200b/200c/429 family recognized the MRE in the 3' UTR of AP-2α gene and negatively regulated the expression of endogenous AP-2α proteins. SNP rs1045385 A>C variation enhanced AP-2α expression by disrupting the binding of the miR-200b/200c/429 family to the 3' UTR of AP-2α. The effects of the two polymorphic variants on cisplatin sensitivity were determined by clonogenic assay. The overexpression of AP-2α with mutant 3' UTR (C allele) in the endometrial cancer cell line HEC-1A, which has high levels of endogenous miR-200b/200c/429 and low levels of AP-2α protein, significantly increased cisplatin sensitivity, but overexpression of A allele of AP-2α has no significant effects, compared with mock transfection. We concluded that miR-200b/200c/429 induced cisplatin resistance by repressing AP-2α expression in endometrial cancer cells. The SNP (rs1045385) A>C variation decreased the binding of miR-200b/200c/429 to the 3' UTR of AP-2α, which upregulated AP-2α protein expression and increased cisplatin sensitivity. Our results suggest that SNP (rs1045385) may be a potential prognostic marker for cisplatin treatment. 7011 hsa-mir-34a Colonic Neoplasms 22198213 MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1. 7012 hsa-mir-20a Colorectal Neoplasms 22202009 miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks. 7013 hsa-mir-21 Colorectal Neoplasms 22202009 miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks. 7014 hsa-mir-106a Colorectal Neoplasms 22202009 miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks. 7015 hsa-mir-181b-1 Colorectal Neoplasms 22202009 miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks. 7016 hsa-mir-181b-2 Colorectal Neoplasms 22202009 miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks. 7017 hsa-mir-203 Colorectal Neoplasms 22202009 miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks. 7018 hsa-mir-324 Colorectal Neoplasms 22202009 miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks. 7019 hsa-mir-210 Pre-Eclampsia 22203747 Hydroxysteroid (17-beta) Dehydrogenase 1 Is Dysregulated by Mir-210 and Mir-518c That Are Aberrantly Expressed in Preeclamptic Placentas. 7020 hsa-mir-518c Pre-Eclampsia 22203747 Hydroxysteroid (17-beta) Dehydrogenase 1 Is Dysregulated by Mir-210 and Mir-518c That Are Aberrantly Expressed in Preeclamptic Placentas. 7021 hsa-mir-192 Stomach Neoplasms 22205577 The down-regulation of miR-192 and -215 was demonstrated to be associated with increased tumor sizes and advanced Borrmann type tumors. 7022 hsa-mir-181d Glioma 22207524 MiR-181d acts as a tumor suppressor in glioma by targeting K-ras and Bcl-2. 7023 hsa-mir-203 Breast Neoplasms 22207897 Anti-miR-203 Upregulates SOCS3 Expression in Breast Cancer Cells and Enhances Cisplatin Chemosensitivity. 7024 hsa-mir-181a-1 Leukemia 22209977 miR-181a sensitizes resistant leukaemia HL-60/Ara-C cells to Ara-C by inducing apoptosis. 7025 hsa-mir-1-1 Prostatic Neoplasms 22210864 MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer. 7026 hsa-mir-1-2 Prostatic Neoplasms 22210864 MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer. 7027 hsa-mir-21 Diabetic Nephropathies 22211842 TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated. 7028 hsa-mir-192 Diabetic Nephropathies 22211842 TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated. 7029 hsa-mir-29a Diabetic Nephropathies 22211842 TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated. 7030 hsa-mir-29b-1 Diabetic Nephropathies 22211842 TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated. 7031 hsa-mir-29b-2 Diabetic Nephropathies 22211842 TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated. 7032 hsa-mir-29c Diabetic Nephropathies 22211842 TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated. 7033 hsa-mir-200a Diabetic Nephropathies 22211842 TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated. 7034 hsa-mir-200b Diabetic Nephropathies 22211842 TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated. 7035 hsa-mir-200c Diabetic Nephropathies 22211842 TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated. 7036 hsa-mir-31 Stomach Neoplasms 22212233 PDCD4 expression inversely correlated with miR-21 levels in gastric cancers. 7037 hsa-mir-520e Carcinoma, Hepatocellular 22212428 A novel tumor suppressor miRNA miR-520e contributes to suppression of hepatoma. 7038 hsa-mir-21 Carcinoma, Hepatocellular 22213236 up-regulated in HCC tissues.correlated with cirrhosis;associated with tumor stage and poor prognosis. 7039 hsa-mir-31 Carcinoma, Hepatocellular 22213236 up-regulated in HCC tissues.correlated with cirrhosis 7040 hsa-mir-122 Carcinoma, Hepatocellular 22213236 up-regulated in HCC tissues.correlated with cirrhosis 7041 hsa-mir-221 Carcinoma, Hepatocellular 22213236 up-regulated in HCC tissues.correlated with cirrhosis;associated with tumor stage and poor prognosis. 7042 hsa-mir-222 Carcinoma, Hepatocellular 22213236 up-regulated in HCC tissues. 7043 hsa-mir-145 Carcinoma, Hepatocellular 22213236 down-regulated in HCC tissues. 7044 hsa-mir-146a Carcinoma, Hepatocellular 22213236 down-regulated in HCC tissues. 7045 hsa-mir-200c Carcinoma, Hepatocellular 22213236 down-regulated in HCC tissues. 7046 hsa-mir-223 Carcinoma, Hepatocellular 22213236 down-regulated in HCC tissues. 7047 hsa-mir-125b-1 Melanoma 22213330 Treatment with 5-Aza, but not with TSA, reduced the expression of miR-125b in the 1,25(OH)(2)D(3)-responsive and -resistant melanoma cell lines and in the NHM. 7048 hsa-mir-27b Melanoma 22213330 Treatment with 1,25(OH)(2)D(3) and/or epigenetic drugs (5-Aza, TSA) reduced the miR-27b expression in three out of four melanoma cell lines. 7049 hsa-mir-125b-2 Melanoma 22213330 Treatment with 5-Aza, but not with TSA, reduced the expression of miR-125b in the 1,25(OH)(2)D(3)-responsive and -resistant melanoma cell lines and in the NHM. 7050 hsa-mir-21 Muscular Dystrophy, Duchenne 22213800 PAI-1-regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy. 7051 hsa-mir-195 Glioblastoma 22217655 MicroRNA-195 plays a tumor-suppressor role in human glioblastoma cells by targeting signaling pathways involved in cellular proliferation and invasion. 7052 hsa-mir-146a Lupus Erythematosus, Systemic 22218224 The SNP (rs2431697) was associated with the microRNA-146a, where the risk allele correlates with lower expression of the miRNA. 7053 hsa-mir-26b Hypertrophy 22219180 GATA4 expression is primarily regulated via a miR-26b-dependent post-transcriptional mechanism during cardiac hypertrophy. 7054 hsa-mir-196a-2 Abortion, Habitual 22222140 RSA(recurrent spontaneous abortion) patients exhibited significantly different frequencies of the miR-196a2CC (TT+TC vs. CC; adjusted odds ratio [AOR], 1.587; 95% confidence interval [CI], 1.042-2.417) and miR-499AG+GG genotypes (AOR, 1.671; 95% CI, 1.054-2.651) compared with the control group. 7055 hsa-mir-499a Abortion, Habitual 22222140 RSA(recurrent spontaneous abortion) patients exhibited significantly different frequencies of the miR-196a2CC (TT+TC vs. CC; adjusted odds ratio [AOR], 1.587; 95% confidence interval [CI], 1.042-2.417) and miR-499AG+GG genotypes (AOR, 1.671; 95% CI, 1.054-2.651) compared with the control group. 7056 hsa-mir-200c Melanoma 22223089 miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors. 7057 hsa-mir-205 Melanoma 22223089 miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors. 7058 hsa-mir-211 Melanoma 22223089 miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors. 7059 hsa-mir-483 Diabetes Mellitus, Type 2 22223106 Increased miR-483-3p expression in vivo, programmed by early-life nutrition, limits storage of lipids in adipose tissue, causing lipotoxicity and insulin resistance and thus increasing susceptibility to metabolic disease. 7060 hsa-mir-1236 Inflammation 22223733 Mirtron MicroRNA-1236 Inhibits VEGFR-3 Signaling During Inflammatory Lymphangiogenesis. 7061 hsa-mir-192 Diabetic Nephropathies 22223877 Inhibiting MicroRNA-192 Ameliorates Renal Fibrosis in Diabetic Nephropathy 7062 hsa-mir-17 Schizophrenia 22228753 Expression of NPAS3 in the Human Cortex is regulated by miR-17 During Development and has Implications for Schizophrenia. 7063 hsa-mir-23b Breast Neoplasms 22231442 ERalpha downregulates miR-30a by binding to two specific sites proximal to the gene and thereby inhibiting pri-miR synthesis. On the other hand, the receptor promotes miR-23b, -27b and 24-1 accumulation in the cell by binding in close proximity of the corresponding gene cluster and preventing in situ the inhibitory effects of ERα on pri-miR maturation by the p68/DDX5-Drosha microprocessor complex. 7064 hsa-mir-27b Breast Neoplasms 22231442 ERalpha downregulates miR-30a by binding to two specific sites proximal to the gene and thereby inhibiting pri-miR synthesis. On the other hand, the receptor promotes miR-23b, -27b and 24-1 accumulation in the cell by binding in close proximity of the corresponding gene cluster and preventing in situ the inhibitory effects of ERα on pri-miR maturation by the p68/DDX5-Drosha microprocessor complex. 7065 hsa-mir-24-1 Breast Neoplasms 22231442 ERalpha downregulates miR-30a by binding to two specific sites proximal to the gene and thereby inhibiting pri-miR synthesis. On the other hand, the receptor promotes miR-23b, -27b and 24-1 accumulation in the cell by binding in close proximity of the corresponding gene cluster and preventing in situ the inhibitory effects of ERα on pri-miR maturation by the p68/DDX5-Drosha microprocessor complex. 7066 hsa-mir-30a Breast Neoplasms 22231442 ERalpha downregulates miR-30a by binding to two specific sites proximal to the gene and thereby inhibiting pri-miR synthesis. On the other hand, the receptor promotes miR-23b, -27b and 24-1 accumulation in the cell by binding in close proximity of the corresponding gene cluster and preventing in situ the inhibitory effects of ERα on pri-miR maturation by the p68/DDX5-Drosha microprocessor complex. 7067 hsa-mir-200b Breast Neoplasms 22231446 Methylation of functional promoters of the Hsa-mir-200b is associated with metastasis or hormone receptor status in advanced breast cancer. 7068 hsa-mir-614 Multiple Sclerosis 22231906 Six plasma miRNA (miR-614, miR-572, miR-648, miR-1826, miR-422a and miR-22) that were significantly up-regulated and one plasma miRNA (miR-1979) that was significantly down-regulated in MS individuals. 7069 hsa-mir-572 Multiple Sclerosis 22231906 Six plasma miRNA (miR-614, miR-572, miR-648, miR-1826, miR-422a and miR-22) that were significantly up-regulated and one plasma miRNA (miR-1979) that was significantly down-regulated in MS individuals. 7070 hsa-mir-648 Multiple Sclerosis 22231906 Six plasma miRNA (miR-614, miR-572, miR-648, miR-1826, miR-422a and miR-22) that were significantly up-regulated and one plasma miRNA (miR-1979) that was significantly down-regulated in MS individuals. 7071 hsa-mir-422a Multiple Sclerosis 22231906 Six plasma miRNA (miR-614, miR-572, miR-648, miR-1826, miR-422a and miR-22) that were significantly up-regulated and one plasma miRNA (miR-1979) that was significantly down-regulated in MS individuals. 7072 hsa-mir-22 Multiple Sclerosis 22231906 Six plasma miRNA (miR-614, miR-572, miR-648, miR-1826, miR-422a and miR-22) that were significantly up-regulated and one plasma miRNA (miR-1979) that was significantly down-regulated in MS individuals. 7073 hsa-mir-375 Head and Neck Neoplasms 22234174 Low-Level Expression of miR-375 Correlates with Poor Outcome and Metastasis While Altering the Invasive Properties of Head and Neck Squamous Cell Carcinomas. 7074 hsa-mir-650 Leukemia, Lymphocytic, Chronic, B-Cell 22234685 MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia. 7075 hsa-mir-7-1 Carcinoma, Hepatocellular 22234835 miR-7 inhibits tumor growth and metastasis by targeting the PI3K/AKT pathway in hepatocellular carcinoma. 7076 hsa-mir-7-2 Carcinoma, Hepatocellular 22234835 miR-7 inhibits tumor growth and metastasis by targeting the PI3K/AKT pathway in hepatocellular carcinoma. 7077 hsa-mir-7-3 Carcinoma, Hepatocellular 22234835 miR-7 inhibits tumor growth and metastasis by targeting the PI3K/AKT pathway in hepatocellular carcinoma. 7078 hsa-mir-17 Ovarian Neoplasms 22235027 The most notable cluster is the tumorigenic miR-17-92 cluster with five microRNAs, all of which are significantly associated with rs3814113 7079 hsa-mir-18a Ovarian Neoplasms 22235027 The most notable cluster is the tumorigenic miR-17-92 cluster with five microRNAs, all of which are significantly associated with rs3814113 7080 hsa-mir-19a Ovarian Neoplasms 22235027 The most notable cluster is the tumorigenic miR-17-92 cluster with five microRNAs, all of which are significantly associated with rs3814113 7081 hsa-mir-20a Ovarian Neoplasms 22235027 The most notable cluster is the tumorigenic miR-17-92 cluster with five microRNAs, all of which are significantly associated with rs3814113 7082 hsa-mir-19b-1 Ovarian Neoplasms 22235027 The most notable cluster is the tumorigenic miR-17-92 cluster with five microRNAs, all of which are significantly associated with rs3814113 7083 hsa-mir-92a-1 Ovarian Neoplasms 22235027 The most notable cluster is the tumorigenic miR-17-92 cluster with five microRNAs, all of which are significantly associated with rs3814113 7084 hsa-mir-122 Lymphoma 22235305 miR-122 regulates p53/Akt signalling and the chemotherapy-induced apoptosis in cutaneous T-cell lymphoma. 7085 hsa-mir-34a Prostatic Neoplasms 22235332 MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells. 7086 hsa-mir-211 Colorectal Neoplasms 22235338 MicroRNA-211 expression promotes colorectal cancer cell growth in vitro and in vivo by targeting tumor suppressor CHD5. 7087 hsa-mir-203 Melanoma 22235882 A decreased expression of miR-203 was significantly associated with a shorter survival time. Also, miR-203 and -205 were markedly down-regulated in canine and human MM cell lines tested. 7088 hsa-mir-205 Melanoma 22235882 A decreased expression of miR-203 was significantly associated with a shorter survival time. Also, miR-203 and -205 were markedly down-regulated in canine and human MM cell lines tested. 7089 hsa-mir-21 Carcinoma, Non-Small-Cell Lung 22237007 Increased miR-21 expression significantly increased the resistance of A549 cell to platinum, whereas reduced miR-21 decreased the resistance of A549/CDDP cell. 7090 hsa-mir-218-1 Uterine Cervical Neoplasms 22237456 Circulating microRNA-218 was reduced in cervical cancer and correlated with tumor invasion. 7091 hsa-mir-218-2 Uterine Cervical Neoplasms 22237456 Circulating microRNA-218 was reduced in cervical cancer and correlated with tumor invasion. 7092 hsa-mir-155 Leukemia, Lymphocytic, Chronic, B-Cell 22238073 SOCS1 is significantly up-regulated in Nutlin-3-treated p53(wild-type) B chronic lymphocytic leukemia (B-CLL) samples and shows an inverse correlation with miR-155. 7093 hsa-mir-122 Hepatitis B 22239527 Serum miR-122 levels are strongly correlated with HBs antigen. 7094 hsa-mir-28 Colorectal Neoplasms 22240480 miR-28-5p altered expression of CCND1 and HOXB3, whereas miR-28-3p bound NM23-H1. Overexpression of miR-28-5p reduced CRC cell proliferation, migration, and invasion in vitro, whereas miR-28-3p increased CRC cell migration and invasion in vitro. 7095 hsa-mir-141 Prostatic Neoplasms 22240788 Circulating miR-141 and miR-375 have association with metastatic prostate cancer. 7096 hsa-mir-375 Prostatic Neoplasms 22240788 Circulating miR-141 and miR-375 have association with metastatic prostate cancer. 7097 hsa-mir-107 Prostatic Neoplasms 22240788 miR-107 and miR-574-3p were quantified at significantly higher concentrations in the urine of men with prostate cancer compared with controls. 7098 hsa-mir-574 Prostatic Neoplasms 22240788 miR-107 and miR-574-3p were quantified at significantly higher concentrations in the urine of men with prostate cancer compared with controls. 7099 hsa-mir-212 Leukemia, Myelogenous, Chronic, BCR-ABL Positive 22241070 ABCG2 protein was 7.2-fold elevated after long-term treatment with imatinib and decreased gradually at higher concentrations. miRNAs miR-212 and miR-328 were identified to correlate inversely with ABCG2 expression under these conditions. 7100 hsa-mir-328 Leukemia, Myelogenous, Chronic, BCR-ABL Positive 22241070 ABCG2 protein was 7.2-fold elevated after long-term treatment with imatinib and decreased gradually at higher concentrations. miRNAs miR-212 and miR-328 were identified to correlate inversely with ABCG2 expression under these conditions. 7101 hsa-mir-122 Colorectal Neoplasms 22241525 Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143) 7102 hsa-mir-181a-1 Colorectal Neoplasms 22241525 Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143) 7103 hsa-mir-181a-2 Colorectal Neoplasms 22241525 Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143) 7104 hsa-mir-146b Colorectal Neoplasms 22241525 Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143) 7105 hsa-let-7e Colorectal Neoplasms 22241525 Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143) 7106 hsa-mir-17 Colorectal Neoplasms 22241525 Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143) 7107 hsa-mir-143 Colorectal Neoplasms 22241525 Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143) 7108 hsa-mir-483 Pheochromocytoma 22241719 miR-483-5p, miR-183, and miR-101 had significantly higher expression in malignant tumors as compared to their benign counterparts. 7109 hsa-mir-101-1 Pheochromocytoma 22241719 miR-483-5p, miR-183, and miR-101 had significantly higher expression in malignant tumors as compared to their benign counterparts. 7110 hsa-mir-101-2 Pheochromocytoma 22241719 miR-483-5p, miR-183, and miR-101 had significantly higher expression in malignant tumors as compared to their benign counterparts. 7111 hsa-mir-183 Pheochromocytoma 22241719 miR-483-5p, miR-183, and miR-101 had significantly higher expression in malignant tumors as compared to their benign counterparts. 7112 hsa-mir-4306 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients 7113 hsa-mir-202 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients 7114 hsa-mir-4257 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients 7115 hsa-mir-1323 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients 7116 hsa-mir-335 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients 7117 hsa-mir-497 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients 7118 hsa-mir-106b Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients 7119 hsa-mir-922 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients 7120 hsa-mir-516b-1 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients 7121 hsa-mir-516b-2 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients 7122 hsa-let-7a-1 Breast Neoplasms 22242178 let-7a* is up-regulated in whole blood of breast cancer patients 7123 hsa-let-7a-2 Breast Neoplasms 22242178 let-7a* is up-regulated in whole blood of breast cancer patients 7124 hsa-let-7a-3 Breast Neoplasms 22242178 let-7a* is up-regulated in whole blood of breast cancer patients 7125 hsa-mir-718 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7126 hsa-mir-625 Breast Neoplasms 22242178 miR-625* is down-regulated in whole blood of breast cancer patients 7127 hsa-mir-1471 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7128 hsa-mir-193a Breast Neoplasms 22242178 miR-193a-3p is down-regulated in whole blood of breast cancer patients 7129 hsa-mir-182 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7130 hsa-mir-1915 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7131 hsa-mir-107 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7132 hsa-mir-2355 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7133 hsa-mir-3186 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7134 hsa-mir-24-1 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7135 hsa-mir-24-2 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7136 hsa-mir-3130-1 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7137 hsa-mir-3130-2 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7138 hsa-mir-526a-1 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7139 hsa-mir-526a-2 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7140 hsa-mir-1469 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7141 hsa-mir-874 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients 7142 hsa-mir-152 Neuroblastoma 22244746 under-expressed in mature neuron. 7143 hsa-mir-146b Neuroblastoma 22244746 under-expressed in mature neuron. 7144 hsa-mir-339 Neuroblastoma 22244746 miR-339-5p: under-expressed in mature neuron. 7145 hsa-mir-370 Neuroblastoma 22244746 under-expressed in neuroblastoma. 7146 hsa-mir-9-1 Neuroblastoma 22244746 under-expressed in neuroblastoma. 7147 hsa-mir-9-2 Neuroblastoma 22244746 under-expressed in neuroblastoma. 7148 hsa-mir-9-3 Neuroblastoma 22244746 under-expressed in neuroblastoma. 7149 hsa-mir-26a-1 Pancreatic Neoplasms 22245693 Metformin up-regulated the expression of miR-26a, miR-192 and let-7c in a dose-dependent manner. Forced expression of miR-26a significantly inhibited cell proliferation, invasion, migration and increased cell apoptosis, whereas knockdown of miR-26a obtained the opposite effect. 7150 hsa-mir-26a-2 Pancreatic Neoplasms 22245693 Metformin up-regulated the expression of miR-26a, miR-192 and let-7c in a dose-dependent manner. Forced expression of miR-26a significantly inhibited cell proliferation, invasion, migration and increased cell apoptosis, whereas knockdown of miR-26a obtained the opposite effect. 7151 hsa-mir-192 Pancreatic Neoplasms 22245693 Metformin up-regulated the expression of miR-26a, miR-192 and let-7c in a dose-dependent manner. 7152 hsa-let-7c Pancreatic Neoplasms 22245693 Metformin up-regulated the expression of miR-26a, miR-192 and let-7c in a dose-dependent manner. 7153 hsa-mir-155 Breast Neoplasms 22245916 Up-regulated miR-155 expression was associated with lymph node positivity (P=0.034), higher proliferation index (Ki-67 >10%) (P=0.019) and advanced breast cancer TNM clinical stage (P=0.002). 7154 hsa-mir-100 Ovarian Neoplasms 22246341 The level of miR-100 was significantly lower in EOC (epithelial ovarian cancer) tissues compared to adjacent normal tissues. Low miR-100 expression was found to be closely correlated with advanced FIGO stage, higher serum CA125 expression level and lymph node involvement. 7155 hsa-mir-34a Laryngeal Neoplasms 22246523 MicroRNA-34a affects the occurrence of laryngeal squamous cell carcinoma by targeting the antiapoptotic gene survivin. 7156 hsa-mir-100 Carcinoma, Hepatocellular 22249248 Sequential analysis of multistage hepatocarcinogenesis reveals that miR-100 and PLK1 dysregulation is an early event maintained along tumor progression. 7157 hsa-mir-210 Myelodysplastic Syndromes 22249254 Loss of SHIP-1 protein expression in high-risk myelodysplastic syndromes is associated with miR-210 and miR-155. 7158 hsa-mir-155 Myelodysplastic Syndromes 22249254 Loss of SHIP-1 protein expression in high-risk myelodysplastic syndromes is associated with miR-210 and miR-155. 7159 hsa-mir-29b-1 Lung Neoplasms 22249264 MicroRNA-29b is involved in the Src-ID1 signaling pathway and is dysregulated in human lung adenocarcinoma. 7160 hsa-mir-29b-2 Lung Neoplasms 22249264 MicroRNA-29b is involved in the Src-ID1 signaling pathway and is dysregulated in human lung adenocarcinoma. 7161 hsa-mir-663a Nasopharyngeal Neoplasms 22249270 MiR-663, a microRNA targeting p21(WAF1/CIP1), promotes the proliferation and tumorigenesis of nasopharyngeal carcinoma. 7162 hsa-mir-21 Mouth Neoplasms 22249446 miR-21 inhibitor sensitizes human OSCC(oral squamous cell carcinoma) cells to cisplatin. 7163 hsa-mir-124-1 Medulloblastoma 22249617 hsa-miR-124a targeted 3'UTR of HMGA1 and negatively modulated the expression in MB cells. 7164 hsa-mir-181a-1 Leukemia, Myeloid, Acute 22251480 Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. 7165 hsa-mir-181a-2 Leukemia, Myeloid, Acute 22251480 Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. 7166 hsa-mir-181b-1 Leukemia, Myeloid, Acute 22251480 Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. 7167 hsa-mir-181b-2 Leukemia, Myeloid, Acute 22251480 Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. 7168 hsa-mir-181c Leukemia, Myeloid, Acute 22251480 Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. 7169 hsa-mir-181d Leukemia, Myeloid, Acute 22251480 Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. 7170 hsa-let-7a-1 Breast Neoplasms 22251626 MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7. 7171 hsa-let-7a-2 Breast Neoplasms 22251626 MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7. 7172 hsa-let-7a-3 Breast Neoplasms 22251626 MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7. 7173 hsa-mir-499a Myocardial Infarction 22252325 Serum miR-499 and hs-cTnT provided comparable diagnostic value with areas under the ROC curves of 0.97. The reclassification index of miR-499 to a clinical model including several risk factors and hs-cTnT was not significant (P = 0.15). 7174 hsa-mir-124-1 Glioma 22253443 Loss of brain-enriched miR-124 enhances the stem-like traits and invasiveness of glioma cells. 7175 hsa-mir-124-2 Glioma 22253443 Loss of brain-enriched miR-124 enhances the stem-like traits and invasiveness of glioma cells. 7176 hsa-mir-124-3 Glioma 22253443 Loss of brain-enriched miR-124 enhances the stem-like traits and invasiveness of glioma cells. 7177 hsa-mir-103a-1 Mesothelioma 22253921 miR-103 was identified as a potential biomarker for malignant mesothelioma 7178 hsa-mir-103a-2 Mesothelioma 22253921 miR-103 was identified as a potential biomarker for malignant mesothelioma 7179 hsa-mir-196a-1 Gastrointestinal Neoplasms 22258453 Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors. 7180 hsa-mir-196a-2 Gastrointestinal Neoplasms 22258453 Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors. 7181 hsa-mir-16-1 Breast Neoplasms 22260523 E2 significantly induced bcl-2, cyclin D1 and survivin expression by suppressing the levels of a panel of miRNAs (miR-16, miR-143, miR-203) in MCF-7 cells. 7182 hsa-mir-16-2 Breast Neoplasms 22260523 E2 significantly induced bcl-2, cyclin D1 and survivin expression by suppressing the levels of a panel of miRNAs (miR-16, miR-143, miR-203) in MCF-7 cells. 7183 hsa-mir-143 Breast Neoplasms 22260523 E2 significantly induced bcl-2, cyclin D1 and survivin expression by suppressing the levels of a panel of miRNAs (miR-16, miR-143, miR-203) in MCF-7 cells. 7184 hsa-mir-203 Breast Neoplasms 22260523 E2 significantly induced bcl-2, cyclin D1 and survivin expression by suppressing the levels of a panel of miRNAs (miR-16, miR-143, miR-203) in MCF-7 cells. 7185 hsa-mir-24-1 Myocardial Infarction 22260784 MicroRNA-24 Regulates Cardiac Fibrosis after Myocardial Infarction. 7186 hsa-mir-24-2 Myocardial Infarction 22260784 MicroRNA-24 Regulates Cardiac Fibrosis after Myocardial Infarction. 7187 hsa-let-7i Pancreatic Neoplasms 22261338 The miRNAs, let-7i and miR-143 was found to target Ras, and forced re-expression of let-7i and miR-143 inhibited Ras activity, cell proliferation and colony formation in vitro. 7188 hsa-mir-143 Pancreatic Neoplasms 22261338 The miRNAs, let-7i and miR-143 was found to target Ras, and forced re-expression of let-7i and miR-143 inhibited Ras activity, cell proliferation and colony formation in vitro. 7189 hsa-mir-519d Carcinoma, Hepatocellular 22262409 In hepatocellular carcinoma miR-519d is upregulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2. 7190 hsa-let-7e Crohn Disease 22262659 The rs10889677 variant in the 3'-untranslated region of the IL-23R gene displays enhanced levels of both mRNA and protein production of IL-23R. This can be attributed to a loss of binding capacity for the microRNAs (miRNAs) Let-7e and Let-7f by the variant allele. 7191 hsa-let-7f-1 Crohn Disease 22262659 The rs10889677 variant in the 3'-untranslated region of the IL-23R gene displays enhanced levels of both mRNA and protein production of IL-23R. This can be attributed to a loss of binding capacity for the microRNAs (miRNAs) Let-7e and Let-7f by the variant allele. 7192 hsa-let-7f-2 Crohn Disease 22262659 The rs10889677 variant in the 3'-untranslated region of the IL-23R gene displays enhanced levels of both mRNA and protein production of IL-23R. This can be attributed to a loss of binding capacity for the microRNAs (miRNAs) Let-7e and Let-7f by the variant allele. 7193 hsa-mir-421 Stomach Neoplasms 22263628 MiR-421 is a functional marker of circulating tumor cells in gastric cancer patients. 7194 hsa-mir-31 Leukemia 22264793 Polycomb-mediated loss of miR-31 activates NIK-dependent NF-kB pathway in adult T cell leukemia and other cancers. 7195 hsa-mir-195 Urinary Bladder Neoplasms 22265971 MicroRNA-195-5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulating GLUT3 expression. 7196 hsa-mir-449a Urinary Bladder Neoplasms 22266187 MicroRNA-449a acts as a tumor suppressor in human bladder cancer through the regulation of pocket proteins. 7197 hsa-mir-133a-1 Head and Neck Neoplasms 22266319 Tumor suppressive microRNA-133a regulates novel targets: Moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma. 7198 hsa-mir-32 Prostatic Neoplasms 22266859 Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer. 7199 hsa-mir-21 Stomach Neoplasms 22267008 microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN. 7200 hsa-mir-21 Colorectal Neoplasms 22267128 Significant inverse correlations were demonstrated between PDCD4 and miR-21. 7201 hsa-mir-221 Liver Cirrhosis 22267590 MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis. 7202 hsa-mir-222 Liver Cirrhosis 22267590 MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis. 7203 hsa-mir-155 Lymphoma 22268450 Epstein-Barr virus latent membrane protein-1 protects B-cell lymphoma from rituximab-induced apoptosis through miR-155-mediated Akt activation and up-regulation of Mcl-1. 7204 hsa-mir-125b-1 Neoplasms 22268450 Camptothecin Induces Apoptosis in Cancer Cells via miR-125b Mediated Mitochondrial Pathways. 7205 hsa-mir-125b-2 Neoplasms 22268450 Camptothecin Induces Apoptosis in Cancer Cells via miR-125b Mediated Mitochondrial Pathways. 7206 hsa-mir-145 Glioma 22269208 Over-expression of miR-145 enhances the effectiveness of HSVtk gene therapy for malignant glioma. 7207 hsa-mir-223 Stomach Neoplasms 22270966 MicroRNA-223 functions as an oncogene in human gastric cancer by targeting FBXW7/hCdc4. 7208 hsa-mir-143 Colorectal Neoplasms 22273643 Down-regulation of fecal miR-143 and miR-145 are potential markers for colorectal cancer. 7209 hsa-mir-145 Colorectal Neoplasms 22273643 Down-regulation of fecal miR-143 and miR-145 are potential markers for colorectal cancer. 7210 hsa-mir-221 Hypertrophy 22275134 MiR-221 promotes cardiac hypertrophy in vitro through the modulation of p27 expression. 7211 hsa-mir-122 Carcinoma, Hepatocellular 22276989 MicroRNA-122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting Wnt/β-catenin pathway. 7212 hsa-mir-125b-1 Breast Neoplasms 22277129 We observed a significant reduction on the expression of miR-125b1 in cancer cells in comparison with controls, suggesting that DNA methylation at the CpG island might reduce miR-125b1 expression. 7213 hsa-mir-21 Aging 22281474 Aging and DMH are associated with increases in CSLC biomarkers and miR21, each of which have been linked to colorectal cancer. 7214 hsa-mir-9-3 Carcinoma, Non-Small-Cell Lung 22282464 Genome-Wide miRNA Expression Profiling Identifies miR-9-3 and miR-193a as Targets for DNA Methylation in Non-Small Cell Lung Cancers. 7215 hsa-mir-193a Carcinoma, Non-Small-Cell Lung 22282464 Genome-Wide miRNA Expression Profiling Identifies miR-9-3 and miR-193a as Targets for DNA Methylation in Non-Small Cell Lung Cancers. 7216 hsa-mir-145 Ovarian Neoplasms 22285623 The loss of miR-145 can result in the activation of factors that promote oncogenesis and cellular pluripotency which in turn could lead to the development of ovarian cancer. 7217 hsa-mir-181a-1 Leukemia 22285729 miR-181a sensitizes a multidrug-resistant leukemia cell line K562/A02 to daunorubicin by targeting BCL-2. 7218 hsa-mir-181a-2 Leukemia 22285729 miR-181a sensitizes a multidrug-resistant leukemia cell line K562/A02 to daunorubicin by targeting BCL-2. 7219 hsa-mir-199a-1 Leukemia 22285730 Low microRNA-199a expression in human amniotic epithelial cell feeder layers maintains human-induced pluripotent stem cell pluripotency via increased leukemia inhibitory factor expression. 7220 hsa-mir-199a-2 Leukemia 22285730 Low microRNA-199a expression in human amniotic epithelial cell feeder layers maintains human-induced pluripotent stem cell pluripotency via increased leukemia inhibitory factor expression. 7221 hsa-mir-21 Leprosy 22286305 MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy 7222 hsa-mir-10b Breast Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. 7223 hsa-mir-17 Breast Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. 7224 hsa-mir-21 Breast Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. 7225 hsa-mir-9-1 Breast Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. 7226 hsa-mir-9-2 Breast Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. 7227 hsa-mir-9-3 Breast Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. 7228 hsa-mir-10b Colonic Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. 7229 hsa-mir-17 Colonic Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. 7230 hsa-mir-21 Colonic Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. 7231 hsa-mir-9-1 Colonic Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. 7232 hsa-mir-9-2 Colonic Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. 7233 hsa-mir-9-3 Colonic Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. 7234 hsa-mir-200a Colorectal Neoplasms 22286765 SIX1-induced CDH1 repression and EMT in CRC cells were correlated at least in part with posttranscriptional ZEB1 activation and miR-200-family transcriptional repression. 7235 hsa-mir-200b Colorectal Neoplasms 22286765 SIX1-induced CDH1 repression and EMT in CRC cells were correlated at least in part with posttranscriptional ZEB1 activation and miR-200-family transcriptional repression. 7236 hsa-mir-200c Colorectal Neoplasms 22286765 SIX1-induced CDH1 repression and EMT in CRC cells were correlated at least in part with posttranscriptional ZEB1 activation and miR-200-family transcriptional repression. 7237 hsa-mir-106b Breast Neoplasms 22286770 The miR-106b-25 cluster targets Smad7, activates TGF-beta signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer. 7238 hsa-mir-25 Breast Neoplasms 22286770 The miR-106b-25 cluster targets Smad7, activates TGF-beta signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer. 7239 hsa-mir-145 Uterine Cervical Neoplasms 22287315 Glucocorticoid regulation of a novel HPV E6-p53-miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells. 7240 hsa-mir-30a Colonic Neoplasms 22287560 MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL. 7241 hsa-mir-127 Inflammation 22287715 MicroRNA-127 Inhibits Lung Inflammation by Targeting IgG Fcgamma Receptor I. 7242 hsa-mir-195 Urinary Bladder Neoplasms 22289176 Cyclin-dependent kinase 4 is a novel target in micoRNA-195-mediated cell cycle arrest in bladder cancer cells. 7243 hsa-mir-31 Breast Neoplasms 22289355 miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer. 7244 hsa-mir-21 Cholesteatoma 22289526 Levels of miR-21 and let-7a microRNA were significantly higher in cholesteatoma tissue compared with normal skin, especially in paediatric patients. 7245 hsa-let-7a-1 Cholesteatoma 22289526 Levels of miR-21 and let-7a microRNA were significantly higher in cholesteatoma tissue compared with normal skin, especially in paediatric patients. 7246 hsa-let-7a-2 Cholesteatoma 22289526 Levels of miR-21 and let-7a microRNA were significantly higher in cholesteatoma tissue compared with normal skin, especially in paediatric patients. 7247 hsa-let-7a-3 Cholesteatoma 22289526 Levels of miR-21 and let-7a microRNA were significantly higher in cholesteatoma tissue compared with normal skin, especially in paediatric patients. 7248 hsa-mir-21 Colorectal Neoplasms 22289545 There was a significantly higher level of miR-21 in CRC tumour tissue than in NAT and high expression of miR-21 was significantly correlated with advanced clinical stage and poor cell differentiation. 7249 hsa-let-7c Carcinoma, Hepatocellular 22289550 Levels of let-7c miRNA were significantly lower in HCC tissues than in corresponding normal adjacent tumour tissues and there was a correlation between the downregulation of let-7c and poor tissue differentiation in HCC. 7250 hsa-mir-29b-1 Carcinoma, Non-Small-Cell Lung 22290228 miR-29b is an upstream molecule of PTEN. miR-29b regulates PTEN gene expression through downregulating Dnmts expression and subsequently induces hypomethylation in PTEN promoter. 7251 hsa-mir-29b-2 Carcinoma, Non-Small-Cell Lung 22290228 miR-29b is an upstream molecule of PTEN. miR-29b regulates PTEN gene expression through downregulating Dnmts expression and subsequently induces hypomethylation in PTEN promoter. 7252 hsa-mir-34a Esophageal Neoplasms 22292433 Transcriptional activation of microRNA-34a by NF-kappa B in human esophageal cancer cells. 7253 hsa-mir-133a-1 Breast Neoplasms 22292984 Loss of miR-133a expression associated with poor survival of breast cancer and restoration of miR-133a expression inhibited breast cancer cell growth and invasion. 7254 hsa-mir-133a-2 Breast Neoplasms 22292984 Loss of miR-133a expression associated with poor survival of breast cancer and restoration of miR-133a expression inhibited breast cancer cell growth and invasion. 7255 hsa-mir-125b-1 Carcinoma, Hepatocellular 22293115 MicroRNA-125b induces cancer cell apoptosis through suppression of Bcl-2 expression. 7256 hsa-mir-125b-2 Carcinoma, Hepatocellular 22293115 MicroRNA-125b induces cancer cell apoptosis through suppression of Bcl-2 expression. 7257 hsa-mir-10b Stomach Neoplasms 22293682 miR-10b promotes cell invasion through RhoC-AKT signaling pathway by targeting HOXD10 in gastric cancer. 7258 hsa-mir-221 Glioblastoma 22294051 miR-221/222 is the regulator of Cx43 expression in human glioblastoma cells. 7259 hsa-mir-200b Crohn Disease 22294131 miR-200b is involved in intestinal fibrosis of Crohn's disease. 7260 hsa-let-7b Breast Neoplasms 22294324 let-7b expression was shown to be associated with luminal tumours, and to have an independent significant positive prognostic value in this group. miR-205 is associated with tumours of ductal morphology, and is of significant positive prognostic value within these tumours. 7261 hsa-mir-205 Breast Neoplasms 22294324 let-7b expression was shown to be associated with luminal tumours, and to have an independent significant positive prognostic value in this group. miR-205 is associated with tumours of ductal morphology, and is of significant positive prognostic value within these tumours. 7262 hsa-mir-9-1 Breast Neoplasms 22294488 The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer. 7263 hsa-mir-9-2 Breast Neoplasms 22294488 The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer. 7264 hsa-mir-9-3 Breast Neoplasms 22294488 The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer. 7265 hsa-mir-200a Breast Neoplasms 22294488 The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer. 7266 hsa-mir-200b Breast Neoplasms 22294488 The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer. 7267 hsa-mir-200c Breast Neoplasms 22294488 The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer. 7268 hsa-mir-1285-1 Carcinoma, Renal Cell 22294552 Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma. 7269 hsa-mir-1285-2 Carcinoma, Renal Cell 22294552 Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma. 7270 hsa-mir-21 Carcinoma, Non-Small-Cell Lung 22295063 The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r?=?0.17, P?=?0.002), though most prominent in the subgroup with nodal metastasis (r?=?0.34, P<0.001). 7271 hsa-mir-155 Carcinoma, Non-Small-Cell Lung 22295063 The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r?=?0.17, P?=?0.002), though most prominent in the subgroup with nodal metastasis (r?=?0.34, P<0.001). 7272 hsa-mir-126 Carcinoma, Non-Small-Cell Lung 22295063 The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r?=?0.17, P?=?0.002), though most prominent in the subgroup with nodal metastasis (r?=?0.34, P<0.001). 7273 hsa-mir-106a Carcinoma, Non-Small-Cell Lung 22295063 The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r?=?0.17, P?=?0.002), though most prominent in the subgroup with nodal metastasis (r?=?0.34, P<0.001). 7274 hsa-mir-182 Carcinoma, Non-Small-Cell Lung 22295063 The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r?=?0.17, P?=?0.002), though most prominent in the subgroup with nodal metastasis (r?=?0.34, P<0.001). 7275 hsa-mir-210 Carcinoma, Non-Small-Cell Lung 22295063 The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r?=?0.17, P?=?0.002), though most prominent in the subgroup with nodal metastasis (r?=?0.34, P<0.001). 7276 hsa-mir-424 Carcinoma, Non-Small-Cell Lung 22295063 The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r?=?0.17, P?=?0.002), though most prominent in the subgroup with nodal metastasis (r?=?0.34, P<0.001). 7277 hsa-mir-152 Atherosclerosis 22295098 MicroRNA-152 mediates DNMT1-regulated DNA methylation in the estrogen receptor α gene. 7278 hsa-mir-638 Lupus Nephritis 22295894 Intra-renal expression of miR-638, miR-198 and miR-146a are differentially expressed between LN patients and normal controls. Furthermore, the degree of change in glomerular miR-146a and tubulointerstitial miR-638 expression correlated with clinical disease severity. 7279 hsa-mir-198 Lupus Nephritis 22295894 Intra-renal expression of miR-638, miR-198 and miR-146a are differentially expressed between LN patients and normal controls. Furthermore, the degree of change in glomerular miR-146a and tubulointerstitial miR-638 expression correlated with clinical disease severity. 7280 hsa-mir-146a Lupus Nephritis 22295894 Intra-renal expression of miR-638, miR-198 and miR-146a are differentially expressed between LN patients and normal controls. Furthermore, the degree of change in glomerular miR-146a and tubulointerstitial miR-638 expression correlated with clinical disease severity. 7281 hsa-mir-20a Prostatic Neoplasms 22298119 miR-20a was significantly overexpressed in plasma from patients with stage 3 tumors compared to stage 2 or below (P?=?0.03). 7282 hsa-mir-21 Prostatic Neoplasms 22298119 The expression levels for miR-20a and miR-21 were significantly increased in patients with high risk CAPRA scores 7283 hsa-mir-21 Prostatic Neoplasms 22298119 The expression levels for miR-20a and miR-21 were significantly increased in patients with high risk CAPRA scores. Significantly increased miR-21 and miR-145 expression were observed for patients with intermediate or high risk D'Amico scores compared to patients with low risk scores 7284 hsa-mir-145 Prostatic Neoplasms 22298119 Significantly increased miR-145 expression were observed for patients with intermediate or high risk D'Amico scores compared to patients with low risk scores 7285 hsa-mir-16-1 Breast Neoplasms 22298638 Serum miR-16, miR-25, miR-222 and miR-324-3p that were consistently differentially expressed between breast cancer cases and controls. 7286 hsa-mir-16-2 Breast Neoplasms 22298638 Serum miR-16, miR-25, miR-222 and miR-324-3p that were consistently differentially expressed between breast cancer cases and controls. 7287 hsa-mir-25 Breast Neoplasms 22298638 Serum miR-16, miR-25, miR-222 and miR-324-3p that were consistently differentially expressed between breast cancer cases and controls. 7288 hsa-mir-222 Breast Neoplasms 22298638 Serum miR-16, miR-25, miR-222 and miR-324-3p that were consistently differentially expressed between breast cancer cases and controls. 7289 hsa-mir-324 Breast Neoplasms 22298638 Serum miR-16, miR-25, miR-222 and miR-324-3p that were consistently differentially expressed between breast cancer cases and controls. 7290 hsa-mir-196b Stomach Neoplasms 22298639 miR-196b expression was significantly repressed by ETS2 during gastric cancer oncogenesis. 7291 hsa-mir-31 Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. 7292 hsa-let-7a-1 Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. 7293 hsa-let-7a-2 Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. 7294 hsa-let-7a-3 Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. 7295 hsa-let-7b Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. 7296 hsa-let-7c Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. 7297 hsa-let-7d Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. 7298 hsa-let-7e Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. 7299 hsa-let-7f-1 Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. 7300 hsa-let-7f-2 Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. 7301 hsa-let-7g Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. 7302 hsa-let-7i Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. 7303 hsa-mir-125b-1 Alzheimer Disease 22302353 miR-125b and miR-146a regulate Complement Factor H (CFH) in Alzheimer's Disease (AD) Brain. 7304 hsa-mir-125b-2 Alzheimer Disease 22302353 miR-125b and miR-146a regulate Complement Factor H (CFH) in Alzheimer's Disease (AD) Brain. 7305 hsa-mir-146a Alzheimer Disease 22302353 miR-125b and miR-146a regulate Complement Factor H (CFH) in Alzheimer's Disease (AD) Brain. 7306 hsa-mir-31 Barrett Esophagus 22302717 The authors propose miR-31 and -375 as novel candidate microRNAs specifically associated with early- and late-stage malignant progression, respectively, in Barrett's esophagus. 7307 hsa-mir-375 Barrett Esophagus 22302717 The authors propose miR-31 and -375 as novel candidate microRNAs specifically associated with early- and late-stage malignant progression, respectively, in Barrett's esophagus. 7308 hsa-mir-27b Lung Neoplasms 22306127 miR-27b and miR-134 levels were significantly lower in the tumors than normal tissue. 7309 hsa-mir-134 Lung Neoplasms 22306127 miR-27b and miR-134 levels were significantly lower in the tumors than normal tissue. 7310 hsa-mir-203 Laryngeal Neoplasms 22306317 MicroRNA-203 leads to G1 phase cell cycle arrest in laryngeal carcinoma cells by directly targeting survivin. 7311 hsa-mir-205 Nasopharyngeal Neoplasms 22306986 MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN. 7312 hsa-mir-21 Lymphoma 22307176 significantly overexpressed in SMZL (splenic marginal zone lymphoma). 7313 hsa-mir-155 Lymphoma 22307176 significantly overexpressed in SMZL (splenic marginal zone lymphoma). 7314 hsa-mir-146a Lymphoma 22307176 significantly overexpressed in SMZL (splenic marginal zone lymphoma). 7315 hsa-mir-139 Lymphoma 22307176 significantly underexpressed in SMZL (splenic marginal zone lymphoma). 7316 hsa-mir-345 Lymphoma 22307176 significantly underexpressed in SMZL (splenic marginal zone lymphoma). 7317 hsa-mir-125a Lymphoma 22307176 significantly underexpressed in SMZL (splenic marginal zone lymphoma). 7318 hsa-mir-126 Lymphoma 22307176 significantly underexpressed in SMZL (splenic marginal zone lymphoma). 7319 hsa-mir-125b-1 Breast Neoplasms 22307404 miR-125b targets ARID3B in breast cancer cells. 7320 hsa-mir-125b-2 Breast Neoplasms 22307404 miR-125b targets ARID3B in breast cancer cells. 7321 hsa-mir-21 Scleroderma, Systemic 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis 7322 hsa-mir-31 Scleroderma, Systemic 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis 7323 hsa-mir-146a Scleroderma, Systemic 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis 7324 hsa-mir-146b Scleroderma, Systemic 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis 7325 hsa-mir-503 Scleroderma, Systemic 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis 7326 hsa-mir-145 Scleroderma, Systemic 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis 7327 hsa-mir-29b-1 Scleroderma, Systemic 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis 7328 hsa-mir-29b-2 Scleroderma, Systemic 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis 7329 hsa-mir-155 Carcinoma, Renal Cell 22307849 microRNA-155 silencing inhibits proliferation and migration and induces apoptosis by upregulating BACH1 in renal cancer cells. 7330 hsa-let-7a-1 Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. 7331 hsa-let-7a-2 Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. 7332 hsa-let-7a-3 Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. 7333 hsa-let-7b Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. 7334 hsa-let-7c Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. 7335 hsa-let-7d Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. 7336 hsa-let-7e Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. 7337 hsa-let-7f-1 Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. 7338 hsa-let-7f-2 Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. 7339 hsa-let-7g Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. 7340 hsa-let-7i Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. 7341 hsa-mir-17 Colorectal Neoplasms 22308110 Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. 7342 hsa-mir-18a Colorectal Neoplasms 22308110 Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. 7343 hsa-mir-19a Colorectal Neoplasms 22308110 Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. 7344 hsa-mir-20a Colorectal Neoplasms 22308110 Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. 7345 hsa-mir-19b-1 Colorectal Neoplasms 22308110 Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. 7346 hsa-mir-92a-1 Colorectal Neoplasms 22308110 Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. 7347 hsa-mir-132 Prostatic Neoplasms 22310291 DNA methylation silences miR-132 in prostate cancer. 7348 hsa-mir-9-1 Hodgkin Disease 22310293 Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo. 7349 hsa-mir-9-2 Hodgkin Disease 22310293 Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo. 7350 hsa-mir-9-3 Hodgkin Disease 22310293 Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo. 7351 hsa-mir-181c Fanconi Anemia 22310912 Downregulated expression of hsa-miR-181c in Fanconi anemia patients: implications in TNFα regulation and proliferation of hematopoietic progenitor cells. 7352 hsa-mir-135a-1 Stomach Neoplasms 22310976 MiR-135a targets JAK2 and inhibits gastric cancer cell proliferation. 7353 hsa-mir-135a-2 Stomach Neoplasms 22310976 MiR-135a targets JAK2 and inhibits gastric cancer cell proliferation. 7354 hsa-mir-499a Carcinoma, Hepatocellular 22311030 hsa-mir-499 (rs3746444; adenine to guanine [C-T]) .Significant differences were found in frequency and distribution of the genotypes of miRNA-499 between the HCC and the control group. Compared with miRNA-499 T/T, the odds ratio (OR) of patients with miRNA-499 C/C for developing HCC was 3.630 (95% CI: 1.545-8.532), and OR for developing HBV-related HCC was 3.133 (95% CI: 1.248-7.861). 7355 hsa-mir-200b Stomach Neoplasms 22311119 MicroRNA-200b Regulates Cell Proliferation, Invasion, and Migration by Directly Targeting ZEB2 in Gastric Carcinoma. 7356 hsa-mir-146a Pancreatic Neoplasms 22311263 Aberrant elevated microRNA-146a in dendritic cells (DC) induced by human pancreatic cancer cell line BxPC-3-conditioned medium inhibits DC maturation and activation. 7357 hsa-mir-122 Carcinoma, Hepatocellular 22312705 MiR-122 increases sensitivity of drug-resistant BEL-7402/5-FU cells to 5-fluorouracil via down-regulation of bcl-2 family proteins. 7358 hsa-mir-141 Prostatic Neoplasms 22314666 miR-141 modulates androgen receptor transcriptional activity in human prostate cancer cells through targeting the small heterodimer partner protein. 7359 hsa-mir-1322 Esophageal Neoplasms 22315007 miR-1322 could significantly down-regulate the ECRG2 with TCA3 allele (P??0.05). MicroRNA-1322 regulates ECRG2 allele specifically and acts as a potential biomarker in patients with esophageal squamous cell carcinoma. 7360 hsa-mir-132 Schizophrenia 22315408 MicroRNA-132 downregulation in schizophrenia has implications for both neurodevelopment and adult brain function. 7361 hsa-let-7d Breast Neoplasms 22315424 let-7d, miR-210, and -221 were down-regulated in the in situ and up-regulated in the invasive transition, thus featuring an expression reversal along the cancer progression path. 7362 hsa-mir-210 Breast Neoplasms 22315424 let-7d, miR-210, and -221 were down-regulated in the in situ and up-regulated in the invasive transition, thus featuring an expression reversal along the cancer progression path. 7363 hsa-mir-221 Breast Neoplasms 22315424 let-7d, miR-210, and -221 were down-regulated in the in situ and up-regulated in the invasive transition, thus featuring an expression reversal along the cancer progression path. 7364 hsa-mir-21 Breast Neoplasms 22315424 Five noncoding genes were associated with both prognostic signatures-miR-210, -21, -106b*, -197, and let-7i, with miR-210 the only one also involved in the invasive transition. 7365 hsa-mir-106b Breast Neoplasms 22315424 Five noncoding genes were associated with both prognostic signatures-miR-210, -21, -106b*, -197, and let-7i, with miR-210 the only one also involved in the invasive transition. 7366 hsa-mir-197 Breast Neoplasms 22315424 Five noncoding genes were associated with both prognostic signatures-miR-210, -21, -106b*, -197, and let-7i, with miR-210 the only one also involved in the invasive transition. 7367 hsa-let-7i Breast Neoplasms 22315424 Five noncoding genes were associated with both prognostic signatures-miR-210, -21, -106b*, -197, and let-7i, with miR-210 the only one also involved in the invasive transition. 7368 hsa-mir-10b Mouth Neoplasms 22318752 hsa-mir-10b has the potential for Oncogenic Function and Early Detection in Oral Cancer as Identified by microRNA Profiling. 7369 hsa-mir-23a Carcinoma, Hepatocellular 22318941 Stat3-mediated activation of miR-23a suppresses gluconeogenesis in hepatocellular carcinoma by downregulating G6PC and PGC-1α 7370 hsa-mir-1207 Glomerulonephritis 22319602 A miR-1207-5p binding site polymorphism (C1936T, rs13385) abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy. 7371 hsa-mir-520b Carcinoma, Hepatocellular 22319632 MicroRNA-520b inhibits growth of hepatoma cells by targeting MEKK2 and cyclin D1. 7372 hsa-mir-30c-1 Carcinoma, Hepatocellular 22320217 miR-30c-1* promotes natural killer cell cytotoxicity against human hepatoma cells by targeting the transcription factor HMBOX1. 7373 hsa-mir-30c-2 Carcinoma, Hepatocellular 22320217 miR-30c-1* promotes natural killer cell cytotoxicity against human hepatoma cells by targeting the transcription factor HMBOX1. 7374 hsa-mir-21 Laryngeal Neoplasms 22320969 Mir-21 was up-regulated in LSCCs and HSCCs compared to adjacent non-tumor tissues (P < 0.05), and the up-regulated expression of mir-21 was associated with clinical stage (P = 0.001), T classification (P = 0.007), pathologic differentiation (P = 0.025), and lymph node positivity (P = 0.002). 7375 hsa-mir-21 Hypopharyngeal Neoplasms 22320969 Mir-21 was up-regulated in LSCCs (laryngeal squamous cell carcinomas) and HSCCs(hypopharyngeal squamous cell carcinomas) compared to adjacent non-tumor tissues (P < 0.05), and the up-regulated expression of mir-21 was associated with clinical stage (P = 0.001), T classification (P = 0.007), pathologic differentiation (P = 0.025), and lymph node positivity (P = 0.002). 7376 hsa-mir-222 Stomach Neoplasms 22321642 Increased miR-222 in H. pylori-associated gastric cancer correlated with tumor progression by promoting cancer cell proliferation and targeting RECK. 7377 hsa-mir-223 Lymphoproliferative Disorders 22321781 The down-regulation of microRNA-223 was associated with disease aggressiveness in CLL. 7378 hsa-mir-21 Carcinoma, Hepatocellular 22322403 miR-21 promotes migration and invasion by the miR-21-PDCD4-AP-1 feedback loop in human hepatocellular carcinoma. 7379 hsa-mir-21 Colonic Neoplasms 22322462 microRNA-21-mediated regulation of Sprouty2 protein expression enhances the cytotoxic effect of 5-fluorouracil and metformin in colon cancer cells. 7380 hsa-mir-182 Ovarian Neoplasms 22322863 miR-182 overexpression resulted in increased tumor transformation in vitro, and enhanced tumor invasiveness in vitro and metastasis in vivo. The oncogenic properties of miR-182 in ovarian cancer were mediated in part by its impaired repair of DNA double-strand breaks and negative regulation of breast cancer 1 (BRCA1) and metastasis suppressor 1 (MTSS1) expressions as well as its positive regulation of oncogene high-mobility group AT-hook 2 (HMGA2). 7381 hsa-mir-125a Stomach Neoplasms 22322911 Low expression levels of miR-125a-3p were associated with indicators of enhanced malignant potential such as tumor size (p=0.0002), tumor invasion (p=0.0149), lymph node metastasis (p=0.018), liver metastasis (p=0.016), peritoneal dissemination (p=0.03), advanced clinical stage (p=0.0037) and poor prognosis (p=0.0083). 7382 hsa-mir-10b Colorectal Neoplasms 22322955 MicroRNA-10b is a Prognostic Indicator in Colorectal Cancer and Confers Resistance to the Chemotherapeutic Agent 5-Fluorouracil in Colorectal Cancer Cells. 7383 hsa-mir-210 Breast Neoplasms 22323552 High Expression of MicroRNA-210 is an Independent Factor Indicating a Poor Prognosis in Japanese Triple-negative Breast Cancer Patients. 7384 hsa-mir-21 Breast Neoplasms 22323912 High miR-21 expression was associated with mastectomy, larger tumor size, higher stage, higher grade, estrogen receptor (ER) negative, human epidermal growth factor receptor 2 (HER2) positive, HER2 positive breast cancer subtype, high Ki-67 expression, and death. 7385 hsa-mir-33a Lung Neoplasms 22325218 mir-33a was down-regulated by 92.8% and mir-193a-3p by 86.5% in epithelial-mesenchymal transition (EMT) on the expression of microRNAs (miRNAs) in lung cancer A549 cells. 7386 hsa-mir-193a Lung Neoplasms 22325218 mir-33a was down-regulated by 92.8% and mir-193a-3p by 86.5% in epithelial-mesenchymal transition (EMT) on the expression of microRNAs (miRNAs) in lung cancer A549 cells. 7387 hsa-mir-182 Stomach Neoplasms 22325466 MicroRNA-182 targets cAMP-responsive element-binding protein 1 and suppresses cell growth in human gastric adenocarcinoma. 7388 hsa-mir-224 Giant Cell Tumors 22326282 altered expression 7389 hsa-mir-155 Inflammation 22326887 Glucocorticoids inhibit lipopolysaccharide-mediated inflammatory response by downregulating microRNA-155 7390 hsa-mir-22 Colonic Neoplasms 22328083 MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells. 7391 hsa-mir-195 Breast Neoplasms 22328513 miR-195, miR-24-2 and miR-365-2 act as negative regulators of BCL2 through direct binding to their respective binding sites in the 3' UTR of human BCL2 gene.over expression of these miRNAs not only caused an increase in apoptosis but also augmented the apoptotic effect of etoposide in breast cancer MCF7 cells. 7392 hsa-mir-24-2 Breast Neoplasms 22328513 miR-195, miR-24-2 and miR-365-2 act as negative regulators of BCL2 through direct binding to their respective binding sites in the 3' UTR of human BCL2 gene.over expression of these miRNAs not only caused an increase in apoptosis but also augmented the apoptotic effect of etoposide in breast cancer MCF7 cells. 7393 hsa-mir-365b Breast Neoplasms 22328513 miR-195, miR-24-2 and miR-365-2 act as negative regulators of BCL2 through direct binding to their respective binding sites in the 3' UTR of human BCL2 gene.over expression of these miRNAs not only caused an increase in apoptosis but also augmented the apoptotic effect of etoposide in breast cancer MCF7 cells. 7394 hsa-mir-1-1 Myocardial Infarction 22330002 MiR-1, -21 -133a and -423-5p showed a 3- to 10-fold increase and miR-499-5p exhibited >80-fold increase in acute NSTEMI patient vs. CTR. 7395 hsa-mir-1-2 Myocardial Infarction 22330002 MiR-1, -21 -133a and -423-5p showed a 3- to 10-fold increase and miR-499-5p exhibited >80-fold increase in acute NSTEMI patient vs. CTR. 7396 hsa-mir-21 Myocardial Infarction 22330002 MiR-1, -21 -133a and -423-5p showed a 3- to 10-fold increase and miR-499-5p exhibited >80-fold increase in acute NSTEMI patient vs. CTR. 7397 hsa-mir-133a-1 Myocardial Infarction 22330002 MiR-1, -21 -133a and -423-5p showed a 3- to 10-fold increase and miR-499-5p exhibited >80-fold increase in acute NSTEMI patient vs. CTR. 7398 hsa-mir-133a-2 Myocardial Infarction 22330002 MiR-1, -21 -133a and -423-5p showed a 3- to 10-fold increase and miR-499-5p exhibited >80-fold increase in acute NSTEMI patient vs. CTR. 7399 hsa-mir-423 Myocardial Infarction 22330002 MiR-1, -21 -133a and -423-5p showed a 3- to 10-fold increase and miR-499-5p exhibited >80-fold increase in acute NSTEMI patient vs. CTR. 7400 hsa-mir-143 Neoplasms 22330136 Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. 7401 hsa-mir-145 Neoplasms 22330136 Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. 7402 hsa-mir-9-1 Uterine Cervical Neoplasms 22330141 Altered expression of five significantly differentially expressed miRNAs, hsa-miR-9 (1q23.2), hsa-miR-15b (3q25.32), hsa-miR-28-5p (3q27.3), hsa-miR-100 and hsa-miR-125b (both 11q24.1), was directly linked to frequent chromosomal alterations. 7403 hsa-mir-15b Uterine Cervical Neoplasms 22330141 Altered expression of five significantly differentially expressed miRNAs, hsa-miR-9 (1q23.2), hsa-miR-15b (3q25.32), hsa-miR-28-5p (3q27.3), hsa-miR-100 and hsa-miR-125b (both 11q24.1), was directly linked to frequent chromosomal alterations. 7404 hsa-mir-28 Uterine Cervical Neoplasms 22330141 Altered expression of five significantly differentially expressed miRNAs, hsa-miR-9 (1q23.2), hsa-miR-15b (3q25.32), hsa-miR-28-5p (3q27.3), hsa-miR-100 and hsa-miR-125b (both 11q24.1), was directly linked to frequent chromosomal alterations. 7405 hsa-mir-100 Uterine Cervical Neoplasms 22330141 Altered expression of five significantly differentially expressed miRNAs, hsa-miR-9 (1q23.2), hsa-miR-15b (3q25.32), hsa-miR-28-5p (3q27.3), hsa-miR-100 and hsa-miR-125b (both 11q24.1), was directly linked to frequent chromosomal alterations. 7406 hsa-mir-125b-1 Uterine Cervical Neoplasms 22330141 Altered expression of five significantly differentially expressed miRNAs, hsa-miR-9 (1q23.2), hsa-miR-15b (3q25.32), hsa-miR-28-5p (3q27.3), hsa-miR-100 and hsa-miR-125b (both 11q24.1), was directly linked to frequent chromosomal alterations. 7407 hsa-mir-1-1 Rhabdomyosarcoma 22330340 Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma. 7408 hsa-mir-1-2 Rhabdomyosarcoma 22330340 Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma. 7409 hsa-mir-106a Rhabdomyosarcoma 22330340 Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma. 7410 hsa-mir-29a Rhabdomyosarcoma 22330340 Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma. 7411 hsa-mir-29b-1 Rhabdomyosarcoma 22330340 Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma. 7412 hsa-mir-29b-2 Rhabdomyosarcoma 22330340 Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma. 7413 hsa-mir-29c Rhabdomyosarcoma 22330340 Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma. 7414 hsa-mir-29a Breast Neoplasms 22330642 Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly, the authors demonstrate that PR itself is regulated by a progestin-upregulated miRNA, miR-513a-5p, providing a novel mechanism for tight control of PR protein expression. 7415 hsa-mir-29b-1 Breast Neoplasms 22330642 Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly, the authors demonstrate that PR itself is regulated by a progestin-upregulated miRNA, miR-513a-5p, providing a novel mechanism for tight control of PR protein expression. 7416 hsa-mir-29b-2 Breast Neoplasms 22330642 Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly, the authors demonstrate that PR itself is regulated by a progestin-upregulated miRNA, miR-513a-5p, providing a novel mechanism for tight control of PR protein expression. 7417 hsa-mir-29c Breast Neoplasms 22330642 Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly, the authors demonstrate that PR itself is regulated by a progestin-upregulated miRNA, miR-513a-5p, providing a novel mechanism for tight control of PR protein expression. 7418 hsa-mir-513a-1 Breast Neoplasms 22330642 Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly, the authors demonstrate that PR itself is regulated by a progestin-upregulated miRNA, miR-513a-5p, providing a novel mechanism for tight control of PR protein expression. 7419 hsa-mir-513a-2 Breast Neoplasms 22330642 Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly, the authors demonstrate that PR itself is regulated by a progestin-upregulated miRNA, miR-513a-5p, providing a novel mechanism for tight control of PR protein expression. 7420 hsa-mir-145 Carcinoma, Non-Small-Cell Lung 22331473 miR-145* inhibits cell invasion and metastasis, and is associated with brain metastasis. 7421 hsa-mir-124-1 Breast Neoplasms 22333974 miR-124, miR-147 and miR-193a-3p are three novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer. 7422 hsa-mir-124-2 Breast Neoplasms 22333974 miR-124, miR-147 and miR-193a-3p are three novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer. 7423 hsa-mir-124-3 Breast Neoplasms 22333974 miR-124, miR-147 and miR-193a-3p are three novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer. 7424 hsa-mir-147a Breast Neoplasms 22333974 miR-124, miR-147 and miR-193a-3p are three novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer. 7425 hsa-mir-193a Breast Neoplasms 22333974 miR-124, miR-147 and miR-193a-3p are three novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer. 7426 hsa-let-7b Cataract 22334139 Let-7b microRNA expression was demonstrated to be positively associated with patient age (R=0.472; p<0.001). A positive correlation was also observed between higher N, C and P cataract scores and higher expression of let-7b microRNA in patients with age-related cataracts (p<0.001). 7427 hsa-mir-27a Urinary Bladder Neoplasms 22334592 The anticancer activity of CSL in 253JB-V cells is due to induction of ROS and ROS-mediated induction of Sp repressors (ZBTB4/ZBTB10) through downregulation of miR-27a and miR-20a/17-5p. 7428 hsa-mir-20a Urinary Bladder Neoplasms 22334592 The anticancer activity of CSL in 253JB-V cells is due to induction of ROS and ROS-mediated induction of Sp repressors (ZBTB4/ZBTB10) through downregulation of miR-27a and miR-20a/17-5p. 7429 hsa-mir-17 Urinary Bladder Neoplasms 22334592 The anticancer activity of CSL in 253JB-V cells is due to induction of ROS and ROS-mediated induction of Sp repressors (ZBTB4/ZBTB10) through downregulation of miR-27a and miR-20a/17-5p. 7430 hsa-mir-21 Carcinoma, Non-Small-Cell Lung 22335905 Overexpression of miR-21 promotes proliferation and reduces apoptosis in non-small cell lung cancer]. 7431 hsa-mir-21 Glioma 22335906 miR-21 was up-regulated 1.49-fold in SHG-44(R) cells (Radioresistant cell line) relative to the SHG-44 cells. 7432 hsa-mir-15a Breast Neoplasms 22335947 The expression level of miR-15a in MCF-7 cells was lower than that in the MCF-10A cells (0.253:1, P < 0.0001). The expression of MiR-15a was significantly inhibited by Bcl-2 (P < 0.05). 7433 hsa-mir-24-1 Retinoblastoma 22336108 Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development. 7434 hsa-mir-24-2 Retinoblastoma 22336108 Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development. 7435 hsa-mir-141 Aortic Valve Stenosis 22336757 miRNA-141 is a novel regulator of BMP-2-mediated calcification in aortic stenosis. 7436 hsa-mir-199a-2 Sezary Syndrome 22336940 Deep-Sequencing Analysis Reveals that the miR-199a2/214 Cluster within DNM3os Represents the Vast Majority of Aberrantly Expressed MicroRNAs in Sézary Syndrome. 7437 hsa-mir-214 Sezary Syndrome 22336940 Deep-Sequencing Analysis Reveals that the miR-199a2/214 Cluster within DNM3os Represents the Vast Majority of Aberrantly Expressed MicroRNAs in Sézary Syndrome. 7438 hsa-mir-449a Ovarian Neoplasms 22340095 The expressions of miR-449a/b, miR-34b and miR-34c were 19-fold to 21-fold elevated after p53 activation by genotoxic agent adriamycin. 7439 hsa-mir-449b Ovarian Neoplasms 22340095 The expressions of miR-449a/b, miR-34b and miR-34c were 19-fold to 21-fold elevated after p53 activation by genotoxic agent adriamycin. 7440 hsa-mir-34b Ovarian Neoplasms 22340095 The expressions of miR-449a/b, miR-34b and miR-34c were 19-fold to 21-fold elevated after p53 activation by genotoxic agent adriamycin. 7441 hsa-mir-34c Ovarian Neoplasms 22340095 The expressions of miR-449a/b, miR-34b and miR-34c were 19-fold to 21-fold elevated after p53 activation by genotoxic agent adriamycin. 7442 hsa-mir-21 Prostatic Neoplasms 22341810 miR-21 is an Independent Biochemical Recurrence Predictor and Potential Therapeutic Target for Prostate Cancer. 7443 hsa-mir-122 Hepatitis C 22342424 Suppression of hepatitis C virus replicon by adenovirus vector-mediated expression of tough decoy RNA against miR-122a. 7444 hsa-mir-1-1 Colorectal Neoplasms 22343615 MicroRNA profiling in colorectal cancer highlights miR-1 involvement in MET-dependent proliferation. 7445 hsa-mir-196a-1 Stomach Neoplasms 22343731 MiR-196a Is Up-regulated in Gastric cancer and Promotes Cell proliferation by Down-regulating p27kip1. 7446 hsa-mir-196a-2 Stomach Neoplasms 22343731 MiR-196a Is Up-regulated in Gastric cancer and Promotes Cell proliferation by Down-regulating p27kip1. 7447 hsa-mir-17 Leukemia, Lymphocytic, Chronic, B-Cell 22343732 The miR-17-92 family regulates the response to toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes. 7448 hsa-mir-18a Leukemia, Lymphocytic, Chronic, B-Cell 22343732 The miR-17-92 family regulates the response to toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes. 7449 hsa-mir-19a Leukemia, Lymphocytic, Chronic, B-Cell 22343732 The miR-17-92 family regulates the response to toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes. 7450 hsa-mir-20a Leukemia, Lymphocytic, Chronic, B-Cell 22343732 The miR-17-92 family regulates the response to toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes. 7451 hsa-mir-19b-1 Leukemia, Lymphocytic, Chronic, B-Cell 22343732 The miR-17-92 family regulates the response to toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes. 7452 hsa-mir-92a-1 Leukemia, Lymphocytic, Chronic, B-Cell 22343732 The miR-17-92 family regulates the response to toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes. 7453 hsa-mir-96 Hodgkin Disease 22343918 In cHL cell lines FOXO1 is inactivated by multiple mechanisms, including constitutive activation of AKT/PKB and MAPK/ERK kinases and up-regulation of microRNAs miR-96, miR-182, and miR-183. 7454 hsa-mir-182 Hodgkin Disease 22343918 In cHL cell lines FOXO1 is inactivated by multiple mechanisms, including constitutive activation of AKT/PKB and MAPK/ERK kinases and up-regulation of microRNAs miR-96, miR-182, and miR-183. 7455 hsa-mir-183 Hodgkin Disease 22343918 In cHL cell lines FOXO1 is inactivated by multiple mechanisms, including constitutive activation of AKT/PKB and MAPK/ERK kinases and up-regulation of microRNAs miR-96, miR-182, and miR-183. 7456 hsa-mir-297 Sepsis 22344312 Microarray analysis showed that serum miR-297 and miR-574-5p were differentially expressed in sepsis survivors and nonsurvivors. Upon validation with 118 sepsis patients' samples, these two miRNA expressions were significantly different, with P < 0.001. miR-297 was more closely associated with survival from sepsis, whereas miR-574-5p was associated with death from sepsis. 7457 hsa-mir-574 Sepsis 22344312 Microarray analysis showed that serum miR-297 and miR-574-5p were differentially expressed in sepsis survivors and nonsurvivors. Upon validation with 118 sepsis patients' samples, these two miRNA expressions were significantly different, with P < 0.001. miR-297 was more closely associated with survival from sepsis, whereas miR-574-5p was associated with death from sepsis. 7458 hsa-mir-31 Pancreatic Neoplasms 22344632 Both inhibition and enhanced expression of miR-31 lead to reduced migration and invasion of pancreatic cancer cells. 7459 hsa-mir-21 Fibrosis 22344686 MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways. 7460 hsa-mir-148b Ovarian Neoplasms 22344713 miR-148b was overexpressed in 92.21% (71/77) of the ovarian cancer samples examined, and overexpression of miR-148b in ovarian cancer tissues was not associated with any of the clinicopathological features of patients with ovarian cancer. 7461 hsa-mir-21 Kidney Neoplasms 22347428 Up-Regulation of MicroRNA-21 Correlates with Lower Kidney Cancer Survival. 7462 hsa-mir-155 Lymphoma, Non-Hodgkin 22347493 Variant rs928883, near miR-155, showed an association (OR per A-allele: 2.80 [95% CI: 1.63-4.82]; p(F)?=?0.027) with marginal zone lymphoma that is significant after correction for multiple testing. 7463 hsa-mir-34a Prostatic Neoplasms 22347519 Epigenetic silencing of miR-34a in human prostate cancer cells and tumor tissue specimens can be reversed by BR-DIM treatment. 7464 hsa-mir-1273c Colorectal Neoplasms 22348132 hsa-mir-1273c, hsa-mir-1303 and hsa-mir-567, with frequent and sometimes bi-allelic mutations in MSI tumors. 7465 hsa-mir-1303 Colorectal Neoplasms 22348132 hsa-mir-1273c, hsa-mir-1303 and hsa-mir-567, with frequent and sometimes bi-allelic mutations in MSI tumors. 7466 hsa-mir-567 Colorectal Neoplasms 22348132 hsa-mir-1273c, hsa-mir-1303 and hsa-mir-567, with frequent and sometimes bi-allelic mutations in MSI tumors. 7467 hsa-mir-10a Leukemia, Myeloid, Acute 22348345 miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated Acute Myeloid Leukaemia and its suppression induces cell death. 7468 hsa-mir-29a Lung Neoplasms 22349807 Bberrant expression of miRNAs such as miR-29ab, miR-183, miR-17-5p and miR-127-3P may play an important role in regulating the bio-behavior of TICs (tumor initiating cells). 7469 hsa-mir-29b-1 Lung Neoplasms 22349807 Bberrant expression of miRNAs such as miR-29ab, miR-183, miR-17-5p and miR-127-3P may play an important role in regulating the bio-behavior of TICs (tumor initiating cells). 7470 hsa-mir-29b-2 Lung Neoplasms 22349807 Bberrant expression of miRNAs such as miR-29ab, miR-183, miR-17-5p and miR-127-3P may play an important role in regulating the bio-behavior of TICs (tumor initiating cells). 7471 hsa-mir-183 Lung Neoplasms 22349807 Bberrant expression of miRNAs such as miR-29ab, miR-183, miR-17-5p and miR-127-3P may play an important role in regulating the bio-behavior of TICs (tumor initiating cells). 7472 hsa-mir-17 Lung Neoplasms 22349807 Bberrant expression of miRNAs such as miR-29ab, miR-183, miR-17-5p and miR-127-3P may play an important role in regulating the bio-behavior of TICs (tumor initiating cells). 7473 hsa-mir-127 Lung Neoplasms 22349807 Bberrant expression of miRNAs such as miR-29ab, miR-183, miR-17-5p and miR-127-3P may play an important role in regulating the bio-behavior of TICs (tumor initiating cells). 7474 hsa-mir-25 Lung Neoplasms 22349819 REV3L 3'UTR 460 T>C polymorphism in microRNA(miR-25/32) target sites contributes to lung cancer susceptibility. 7475 hsa-mir-32 Lung Neoplasms 22349819 REV3L 3'UTR 460 T>C polymorphism in microRNA(miR-25/32) target sites contributes to lung cancer susceptibility. 7476 hsa-mir-181b-1 Leukemia, Lymphocytic, Chronic, B-Cell 22350310 miR-181b is a biomarker for the progression of this disease from indolent to aggressive. 7477 hsa-mir-181b-2 Leukemia, Lymphocytic, Chronic, B-Cell 22350310 miR-181b is a biomarker for the progression of this disease from indolent to aggressive. 7478 hsa-mir-155 Liposarcoma 22350414 MiR-155 is a liposarcoma oncogene that targets casein kinase-1α and enhances β-catenin signaling. 7479 hsa-mir-130a Leukemia, Lymphocytic, Chronic, B-Cell 22350415 MicroRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells. 7480 hsa-mir-181a-1 Osteosarcoma 22350417 high expression 7481 hsa-mir-181a-2 Osteosarcoma 22350417 high expression 7482 hsa-mir-181b-1 Osteosarcoma 22350417 high expression 7483 hsa-mir-181b-2 Osteosarcoma 22350417 high expression 7484 hsa-mir-181c Osteosarcoma 22350417 high expression 7485 hsa-mir-16-1 Osteosarcoma 22350417 reduced expression 7486 hsa-mir-16-2 Osteosarcoma 22350417 reduced expression 7487 hsa-mir-29b-1 Osteosarcoma 22350417 reduced expression 7488 hsa-mir-142 Osteosarcoma 22350417 reduced expression 7489 hsa-mir-29b-2 Osteosarcoma 22350417 reduced expression 7490 hsa-mir-27a Stomach Neoplasms 22350505 The SNP rs895819 in the miR-27a gene with the minor allele C presented significantly reduced risk to gastric cancer in Chinese population. 7491 hsa-mir-20a Breast Neoplasms 22350790 Levels of preoperative serum miR-20a and miR-21 were significantly higher in patients with breast cancer and benign disease than in healthy women (p = 0.0001), but only serum miR-214 could discriminate malignant from benign tumors and healthy controls (p = 0.0001) with an area under the curve of 0.878 and 0.883 in ROC analysis, respectively. 7492 hsa-mir-21 Breast Neoplasms 22350790 Levels of preoperative serum miR-20a and miR-21 were significantly higher in patients with breast cancer and benign disease than in healthy women (p = 0.0001), but only serum miR-214 could discriminate malignant from benign tumors and healthy controls (p = 0.0001) with an area under the curve of 0.878 and 0.883 in ROC analysis, respectively. 7493 hsa-mir-214 Breast Neoplasms 22350790 Levels of preoperative serum miR-20a and miR-21 were significantly higher in patients with breast cancer and benign disease than in healthy women (p = 0.0001), but only serum miR-214 could discriminate malignant from benign tumors and healthy controls (p = 0.0001) with an area under the curve of 0.878 and 0.883 in ROC analysis, respectively. 7494 hsa-mir-21 Thyroid Neoplasms 22351693 A SVM model with 4 miRNAs (miR-222, miR-328, miR-197 and miR-21) was initially estimated to have 86% predictive accuracy using cross-validation to differentiate Malignant from Benign. 7495 hsa-mir-222 Thyroid Neoplasms 22351693 A SVM model with 4 miRNAs (miR-222, miR-328, miR-197 and miR-21) was initially estimated to have 86% predictive accuracy using cross-validation to differentiate Malignant from Benign. 7496 hsa-mir-328 Thyroid Neoplasms 22351693 A SVM model with 4 miRNAs (miR-222, miR-328, miR-197 and miR-21) was initially estimated to have 86% predictive accuracy using cross-validation to differentiate Malignant from Benign. 7497 hsa-mir-197 Thyroid Neoplasms 22351693 A SVM model with 4 miRNAs (miR-222, miR-328, miR-197 and miR-21) was initially estimated to have 86% predictive accuracy using cross-validation to differentiate Malignant from Benign. 7498 hsa-let-7i Brain Injuries 22352906 MicroRNA Let-7i is a Promising Serum Biomarker for Blast Induced Traumatic Brain Injury. 7499 hsa-mir-21 Glioblastoma 22353043 Ursolic Acid Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Cell Lines U251 by Suppressing TGF-beta1/miR-21 /PDCD4 Pathway. 7500 hsa-mir-196b Leukemia 22353710 miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia. 7501 hsa-mir-215 Breast Neoplasms 22353773 miR-215, miR-299-5p, miR-411, and miR-452 are differentially expressed between serum samples from patients with cancer and serum samples from healthy controls 7502 hsa-mir-299 Breast Neoplasms 22353773 miR-215, miR-299-5p, miR-411, and miR-452 are differentially expressed between serum samples from patients with cancer and serum samples from healthy controls 7503 hsa-mir-411 Breast Neoplasms 22353773 miR-215, miR-299-5p, miR-411, and miR-452 are differentially expressed between serum samples from patients with cancer and serum samples from healthy controls 7504 hsa-mir-452 Breast Neoplasms 22353773 miR-215, miR-299-5p, miR-411, and miR-452 are differentially expressed between serum samples from patients with cancer and serum samples from healthy controls 7505 hsa-mir-101-1 Colonic Neoplasms 22353936 MicroRNA-101 (miR-101) post-transcriptionally regulates the expression of EP4 receptor in colon cancers. 7506 hsa-mir-101-2 Colonic Neoplasms 22353936 MicroRNA-101 (miR-101) post-transcriptionally regulates the expression of EP4 receptor in colon cancers. 7507 hsa-mir-155 Breast Neoplasms 22354042 A novel miR-155/miR-143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells. 7508 hsa-mir-143 Breast Neoplasms 22354042 A novel miR-155/miR-143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells. 7509 hsa-mir-21 Esophageal Neoplasms 22354855 Serum concentration of miRNA-21 in ESCC patients was significantly higher than that in healthy controls (P?T)) of pri-microRNA 325, targeting SLC6A4 3'-UTR, is closely associated with the risk of functional dyspepsia in Japan. 7882 hsa-mir-34a Carcinoma, Non-Small-Cell Lung 22438124 Delta-tocotrienol suppresses Notch-1 pathway by up-regulating miR-34a in non-small cell lung cancer cells. 7883 hsa-mir-17 Pre-Eclampsia 22438230 Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta. 7884 hsa-mir-20a Pre-Eclampsia 22438230 Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta. 7885 hsa-mir-20b Pre-Eclampsia 22438230 Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta. 7886 hsa-mir-193a Prostatic Neoplasms 22438885 miR-193a-3p and miRPlus-E1245 observed to be specific to XMRV infection in all 4 cell types (Two prostate cell lines (LNCaP and DU145) and two primary cells). 7887 hsa-let-7c Carcinoma, Small Cell 22438992 Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix. 7888 hsa-mir-100 Carcinoma, Small Cell 22438992 Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix. 7889 hsa-mir-125b-1 Carcinoma, Small Cell 22438992 Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix. 7890 hsa-mir-125b-2 Carcinoma, Small Cell 22438992 Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix. 7891 hsa-mir-143 Carcinoma, Small Cell 22438992 Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix. 7892 hsa-mir-199a-1 Carcinoma, Small Cell 22438992 Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix. 7893 hsa-mir-199a-2 Carcinoma, Small Cell 22438992 Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix. 7894 hsa-mir-145 Carcinoma, Small Cell 22438992 Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix. 7895 hsa-mir-135a-1 Breast Neoplasms 22439757 miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10. 7896 hsa-mir-135a-2 Breast Neoplasms 22439757 miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10. 7897 hsa-mir-34b Breast Neoplasms 22439831 MiR-34b is associated with clinical outcome in triple-negative breast cancer patients.Expression levels of miR-34b significantly correlate with disease free survival (DFS) (p = 0.0020, log-rank test) and overall survival (OS) (p = 0.0008, log-rank test) of TNBC patients. 7898 hsa-mir-760 Carcinoma, Renal Cell 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7899 hsa-mir-629 Carcinoma, Renal Cell 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7900 hsa-mir-26b Carcinoma, Renal Cell 22440013 miR-26b*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7901 hsa-mir-126 Carcinoma, Renal Cell 22440013 miR-126*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7902 hsa-mir-571 Carcinoma, Renal Cell 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7903 hsa-mir-29c Carcinoma, Renal Cell 22440013 miR-29c*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7904 hsa-mir-625 Carcinoma, Renal Cell 22440013 miR-625*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7905 hsa-mir-134 Carcinoma, Renal Cell 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7906 hsa-mir-339 Carcinoma, Renal Cell 22440013 miR-339-3p: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7907 hsa-mir-203 Carcinoma, Renal Cell 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7908 hsa-mir-454 Carcinoma, Renal Cell 22440013 miR-454*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7909 hsa-mir-144 Carcinoma, Renal Cell 22440013 miR-144*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7910 hsa-mir-655 Carcinoma, Renal Cell 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7911 hsa-mir-425 Carcinoma, Renal Cell 22440013 miR-425*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7912 hsa-mir-381 Carcinoma, Renal Cell 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7913 hsa-mir-150 Carcinoma, Renal Cell 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7914 hsa-mir-219-1 Carcinoma, Renal Cell 22440013 miR-219-5p: Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7915 hsa-mir-219-2 Carcinoma, Renal Cell 22440013 miR-219-5p: Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7916 hsa-mir-302b Carcinoma, Renal Cell 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7917 hsa-let-7f-1 Carcinoma, Renal Cell 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7918 hsa-let-7f-2 Carcinoma, Renal Cell 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7919 hsa-let-7a-1 Carcinoma, Renal Cell 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7920 hsa-let-7a-2 Carcinoma, Renal Cell 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7921 hsa-let-7a-3 Carcinoma, Renal Cell 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7922 hsa-mir-19a Carcinoma, Renal Cell 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7923 hsa-mir-302c Carcinoma, Renal Cell 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7924 hsa-mir-367 Carcinoma, Renal Cell 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7925 hsa-mir-142 Carcinoma, Renal Cell 22440013 miR-142-5p: Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7926 hsa-mir-378a Carcinoma, Renal Cell 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7927 hsa-mir-151a Carcinoma, Renal Cell 22440013 miR-151-30: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7928 hsa-mir-151b Carcinoma, Renal Cell 22440013 miR-151-30: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7929 hsa-mir-320a Carcinoma, Renal Cell 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7930 hsa-mir-365a Carcinoma, Renal Cell 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7931 hsa-mir-365b Carcinoma, Renal Cell 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7932 hsa-mir-451a Carcinoma, Renal Cell 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. 7933 hsa-mir-128-1 Glioma 22442669 miR-128 expression levels were decreased in glioma. MiR-128 Inhibits Tumor Growth and Angiogenesis by Targeting p70S6K1. 7934 hsa-mir-128-2 Glioma 22442669 miR-128 expression levels were decreased in glioma. MiR-128 Inhibits Tumor Growth and Angiogenesis by Targeting p70S6K1. 7935 hsa-mir-181a-1 Leukemia, Myelogenous, Chronic, BCR-ABL Positive 22442671 miR-181a Post-Transcriptionally Downregulates Oncogenic RalA and Contributes to Growth Inhibition and Apoptosis in Chronic Myelogenous Leukemia (CML). 7936 hsa-mir-181b-1 Liver Cirrhosis 22446332 miR-181b Promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients. 7937 hsa-mir-181b-2 Liver Cirrhosis 22446332 miR-181b Promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients. 7938 hsa-mir-363 Leiomyoma 22446413 deregulated 7939 hsa-mir-490 Leiomyoma 22446413 deregulated 7940 hsa-mir-137 Leiomyoma 22446413 deregulated 7941 hsa-mir-217 Leiomyoma 22446413 deregulated 7942 hsa-mir-4792 Leiomyoma 22446413 deregulated 7943 hsa-mir-421 Carcinoma, Hepatocellular 22446874 Downregulation of Human Farnesoid X Receptor by miR-421 Promotes Proliferation and Migration of Hepatocellular Carcinoma Cells. 7944 hsa-mir-148a Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM.High levels of miR-20a and miR-148a were related to shorter relapse-free survival. 7945 hsa-mir-181a-1 Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM. 7946 hsa-mir-20a Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM. 7947 hsa-mir-221 Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM.High levels of miR-20a and miR-148a were related to shorter relapse-free survival. 7948 hsa-mir-625 Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM. 7949 hsa-mir-99b Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM. 7950 hsa-mir-181a-2 Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM. 7951 hsa-mir-328 Myopia 22447870 MicroRNA-328 may influence myopia development by mediating the PAX6 gene. 7952 hsa-mir-15a Leukemia 22449094 Pure curcumin decreases the expression of WT1 by upregulation of miR-15a and miR-16-1 in leukemic cells. 7953 hsa-mir-16-1 Leukemia 22449094 Pure curcumin decreases the expression of WT1 by upregulation of miR-15a and miR-16-1 in leukemic cells. 7954 hsa-mir-16-2 Leukemia 22449094 Pure curcumin decreases the expression of WT1 by upregulation of miR-15a and miR-16-1 in leukemic cells. 7955 hsa-mir-219-2 Carcinoma, Hepatocellular 22449976 MiR-219-5p inhibits hepatocellular carcinoma cell proliferation by targeting glypican-3. 7956 hsa-mir-219-1 Carcinoma, Hepatocellular 22449976 MiR-219-5p inhibits hepatocellular carcinoma cell proliferation by targeting glypican-3. 7957 hsa-mir-20a Uterine Cervical Neoplasms 22449978 miR-20a promotes migration and invasion by regulating TNKS2 in human cervical cancer cells. 7958 hsa-mir-25 Esophageal Neoplasms 22450326 MicroRNA-25 promotes cell migration and invasion in esophageal squamous cell carcinoma. 7959 hsa-mir-20a Hypertension 22450430 AntagomiR directed against miR-20a restores functional BMPR2 signalling and prevents vascular remodelling in hypoxia-induced pulmonary hypertension. 7960 hsa-mir-124-1 Stomach Neoplasms 22450659 MiR-124 Inhibits Cell Proliferation in Gastric Cancer through Downregulation of SPHK1. 7961 hsa-mir-124-2 Stomach Neoplasms 22450659 MiR-124 Inhibits Cell Proliferation in Gastric Cancer through Downregulation of SPHK1. 7962 hsa-mir-124-3 Stomach Neoplasms 22450659 MiR-124 Inhibits Cell Proliferation in Gastric Cancer through Downregulation of SPHK1. 7963 hsa-mir-101-1 Stomach Neoplasms 22450781 Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 upregulation in intestinal gastric cancer. 7964 hsa-mir-101-2 Stomach Neoplasms 22450781 Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 upregulation in intestinal gastric cancer. 7965 hsa-let-7c Influenza, Human 22452878 Cellular MicroRNA let-7c Inhibits M1 Protein Expression of the H1N1 Influenza A Virus in Infected Human Lung Epithelial Cells. 7966 hsa-mir-140 Ovarian Neoplasms 22452920 The expression level of RAD51AP1 was found to be strongly anti-correlated with the expression of hsa-miR-140-3p, which was significantly down-regulated in the tumour samples. 7967 hsa-mir-145 Ovarian Neoplasms 22452920 Other pairs of potentially biological relevance include: hsa-miR-145/E2F3, hsa-miR-139-5p/TOP2A, and hsa-miR-133a/GCLC. 7968 hsa-mir-133a-1 Ovarian Neoplasms 22452920 Other pairs of potentially biological relevance include: hsa-miR-145/E2F3, hsa-miR-139-5p/TOP2A, and hsa-miR-133a/GCLC. 7969 hsa-mir-133a-2 Ovarian Neoplasms 22452920 Other pairs of potentially biological relevance include: hsa-miR-145/E2F3, hsa-miR-139-5p/TOP2A, and hsa-miR-133a/GCLC. 7970 hsa-mir-328 Colorectal Neoplasms 22453125 MicroRNA expression profiling identifies miR-328 regulates cancer stem cell-like SP cells in colorectal cancer. 7971 hsa-mir-130a Ovarian Neoplasms 22455133 The over expression of miR-130a is associated with cisplatin resistance of ovarian cancer. Inhibiting miR-130a expression may help reverse the cisplatin resistance of ovarian cancer. 7972 hsa-mir-146a Stomach Neoplasms 22455393 A Functional Polymorphism (rs2910164) in Pre-miR-146a Is Associated with Susceptibility to Gastric Cancer in a Chinese Population. 7973 hsa-mir-23a Colorectal Neoplasms 22455847 MiR-23a expression promotes colon carcinoma cell growth, invasion and metastasis through inhibition of MTSS gene. 7974 hsa-mir-372 Colorectal Neoplasms 22456107 MicroRNA-372 Is Associated with Poor Prognosis in Colorectal Cancer. 7975 hsa-mir-154 Graves Disease 22456620 The expression of miR-154*, miR-376b, and miR-431* were suppressed in PBMC (peripheral blood mononuclear cells) from initial GD patients. In addition, their expression levels were recovered in GD patients in remission. 7976 hsa-mir-376b Graves Disease 22456620 The expression of miR-154*, miR-376b, and miR-431* were suppressed in PBMC (peripheral blood mononuclear cells) from initial GD patients. In addition, their expression levels were recovered in GD patients in remission. 7977 hsa-mir-431 Graves Disease 22456620 The expression of miR-154*, miR-376b, and miR-431* were suppressed in PBMC (peripheral blood mononuclear cells) from initial GD patients. In addition, their expression levels were recovered in GD patients in remission. 7978 hsa-mir-34a Osteosarcoma 22457788 MicroRNA-34a Inhibits the Proliferation and Metastasis of Osteosarcoma Cells Both In Vitro and In Vivo. 7979 hsa-mir-143 Esophageal Neoplasms 22457808 The Cluster of miR-143 and miR-145 Affects the Risk for Esophageal Squamous Cell Carcinoma through Co-Regulating Fascin Homolog 1. 7980 hsa-mir-145 Esophageal Neoplasms 22457808 The Cluster of miR-143 and miR-145 Affects the Risk for Esophageal Squamous Cell Carcinoma through Co-Regulating Fascin Homolog 1. 7981 hsa-mir-224 Carcinoma, Hepatocellular 22459148 MicroRNA-224 is up-regulated in hepatocellular carcinoma through epigenetic mechanisms. 7982 hsa-mir-320a Colorectal Neoplasms 22459450 MicroRNA-320a suppresses human colon cancer cell proliferation by directly targeting beta-catenin. 7983 hsa-mir-125b-1 Endometrial Neoplasms 22460089 MicroRNA-125b down-regulation mediates endometrial cancer invasion by targeting ERBB2. 7984 hsa-mir-125b-2 Endometrial Neoplasms 22460089 MicroRNA-125b down-regulation mediates endometrial cancer invasion by targeting ERBB2. 7985 hsa-mir-15a Multiple Sclerosis 22463747 miR-15a and 16-1 are downregulated in CD4(+) T cells of multiple sclerosis relapsing patients. 7986 hsa-mir-16-1 Multiple Sclerosis 22463747 miR-15a and 16-1 are downregulated in CD4(+) T cells of multiple sclerosis relapsing patients. 7987 hsa-mir-21 Stomach Neoplasms 22464652 MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer. 7988 hsa-mir-483 Glioma 22465663 MiR-483-5p suppresses the proliferation of glioma cells via directly targeting ERK1. 7989 hsa-mir-93 Ovarian Neoplasms 22465665 Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells. 7990 hsa-mir-21 Pancreatic Neoplasms 22466166 Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions. 7991 hsa-mir-221 Pancreatic Neoplasms 22466166 Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions. 7992 hsa-mir-155 Pancreatic Neoplasms 22466166 Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions. 7993 hsa-mir-100 Pancreatic Neoplasms 22466166 Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions. 7994 hsa-mir-181b-1 Pancreatic Neoplasms 22466166 Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions. 7995 hsa-mir-196a-1 Pancreatic Neoplasms 22466166 Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions. 7996 hsa-mir-181b-2 Pancreatic Neoplasms 22466166 Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions. 7997 hsa-mir-196a-2 Pancreatic Neoplasms 22466166 Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions. 7998 hsa-mir-486 Spinal Cord Injuries 22466292 MicroRNA 486 is a potentially novel target for the treatment of spinal cord injury. 7999 hsa-mir-215 Colorectal Neoplasms 22469014 MiR-215, miR-375, miR-378 and miR-422a were significantly decreased, whereas miR-135b was increased in CRC tumor tissues. Levels of miR-215 and miR-422a correlated with clinical stage. 8000 hsa-mir-422a Colorectal Neoplasms 22469014 MiR-215, miR-375, miR-378 and miR-422a were significantly decreased, whereas miR-135b was increased in CRC tumor tissues. Levels of miR-215 and miR-422a correlated with clinical stage. 8001 hsa-mir-378a Colorectal Neoplasms 22469014 MiR-215, miR-375, miR-378 and miR-422a were significantly decreased, whereas miR-135b was increased in CRC tumor tissues. Levels of miR-215 and miR-422a correlated with clinical stage. 8002 hsa-mir-29a Liver Diseases 22469499 Hepatic miR-29ab1 expression modulates chronic hepatic injury. 8003 hsa-mir-29b-1 Liver Diseases 22469499 Hepatic miR-29ab1 expression modulates chronic hepatic injury. 8004 hsa-mir-29b-2 Liver Diseases 22469499 Hepatic miR-29ab1 expression modulates chronic hepatic injury. 8005 hsa-mir-26a-1 Lung Neoplasms 22469510 MicroRNA-26a regulates tumorigenic properties of EZH2 in human lung carcinoma cells. 8006 hsa-mir-26a-2 Lung Neoplasms 22469510 MicroRNA-26a regulates tumorigenic properties of EZH2 in human lung carcinoma cells. 8007 hsa-mir-125b-1 Precursor Cell Lymphoblastic Leukemia-Lymphoma 22469780 B-cell regulator of immunoglobulin heavy chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells. 8008 hsa-mir-125b-2 Precursor Cell Lymphoblastic Leukemia-Lymphoma 22469780 B-cell regulator of immunoglobulin heavy chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells. 8009 hsa-mir-495 Stomach Neoplasms 22469786 MiR-495 and miR-551a inhibit the migration and invasion of human gastric cancer cells by directly interacting with PRL-3. 8010 hsa-mir-551a Stomach Neoplasms 22469786 MiR-495 and miR-551a inhibit the migration and invasion of human gastric cancer cells by directly interacting with PRL-3. 8011 hsa-mir-22 Ovarian Neoplasms 22469921 Tiam1, negatively regulated by miR-22, miR-183 and miR-31, is involved in migration, invasion and viability of ovarian cancer cells. 8012 hsa-mir-183 Ovarian Neoplasms 22469921 Tiam1, negatively regulated by miR-22, miR-183 and miR-31, is involved in migration, invasion and viability of ovarian cancer cells. 8013 hsa-mir-31 Ovarian Neoplasms 22469921 Tiam1, negatively regulated by miR-22, miR-183 and miR-31, is involved in migration, invasion and viability of ovarian cancer cells. 8014 hsa-mir-424 Uterine Cervical Neoplasms 22469983 Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancer. 8015 hsa-mir-143 Head and Neck Neoplasms 22469988 miR-143 regulates hexokinase 2 expression in cancer cells. 8016 hsa-mir-155 Glioblastoma 22470130 miR-155 is up-regulated in primary and secondary glioblastoma and promotes tumour growth by inhibiting GABA receptors. 8017 hsa-mir-140 Mouth Neoplasms 22470160 miR-140-3p, miR-29c, and miR-29a were differentially expressed in metastasis versus nonmetastatic samples and had a strong positive correlation with their DNA copy numbers and a negative correlation with the expression of their target genes. 8018 hsa-mir-29a Mouth Neoplasms 22470160 miR-140-3p, miR-29c, and miR-29a were differentially expressed in metastasis versus nonmetastatic samples and had a strong positive correlation with their DNA copy numbers and a negative correlation with the expression of their target genes. 8019 hsa-mir-29c Mouth Neoplasms 22470160 miR-140-3p, miR-29c, and miR-29a were differentially expressed in metastasis versus nonmetastatic samples and had a strong positive correlation with their DNA copy numbers and a negative correlation with the expression of their target genes. 8020 hsa-mir-223 Stomach Neoplasms 22470493 Stathmin1 Plays Oncogenic Role and Is a Target of MicroRNA-223 in Gastric Cancer. 8021 hsa-let-7e Thyroid Neoplasms 22472564 The expression of serum let-7e, miR-151-5p, and miR-222 was significantly increased in PTC (papillary thyroid carcinomas ) cases relative to benign cases and healthy controls. Serum let-7e, miR-151-5p, and miR-222 levels were found to be well correlated with certain clinicopathological variables, such as nodal status, tumor size, multifocal lesion status, and Tumor-Node-Metastasis stage. 8022 hsa-mir-222 Thyroid Neoplasms 22472564 The expression of serum let-7e, miR-151-5p, and miR-222 was significantly increased in PTC (papillary thyroid carcinomas ) cases relative to benign cases and healthy controls. Serum let-7e, miR-151-5p, and miR-222 levels were found to be well correlated with certain clinicopathological variables, such as nodal status, tumor size, multifocal lesion status, and Tumor-Node-Metastasis stage. 8023 hsa-mir-151a Thyroid Neoplasms 22472564 The expression of serum let-7e, miR-151-5p, and miR-222 was significantly increased in PTC (papillary thyroid carcinomas ) cases relative to benign cases and healthy controls. Serum let-7e, miR-151-5p, and miR-222 levels were found to be well correlated with certain clinicopathological variables, such as nodal status, tumor size, multifocal lesion status, and Tumor-Node-Metastasis stage. 8024 hsa-mir-151b Thyroid Neoplasms 22472564 The expression of serum let-7e, miR-151-5p, and miR-222 was significantly increased in PTC (papillary thyroid carcinomas ) cases relative to benign cases and healthy controls. Serum let-7e, miR-151-5p, and miR-222 levels were found to be well correlated with certain clinicopathological variables, such as nodal status, tumor size, multifocal lesion status, and Tumor-Node-Metastasis stage. 8025 hsa-mir-145 Osteosarcoma 22472569 MicroRNA-145 targets vascular endothelial growth factor and inhibits invasion and metastasis of osteosarcoma cells. 8026 hsa-mir-15a Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8027 hsa-mir-16-1 Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8028 hsa-mir-16-2 Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8029 hsa-mir-195 Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8030 hsa-mir-497 Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8031 hsa-mir-143 Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8032 hsa-mir-145 Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8033 hsa-mir-106a Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8034 hsa-mir-363 Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8035 hsa-mir-18b Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8036 hsa-mir-20b Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8037 hsa-mir-19b-2 Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8038 hsa-mir-92a-2 Carcinoma, Squamous Cell 22472886 The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis. 8039 hsa-mir-17 Precursor Cell Lymphoblastic Leukemia-Lymphoma 22475310 Down-regulation of miR17 plays an important role in glucocorticoid-induced cell death suggesting that targeting miR17 may improve the current ALL combination therapy. 8040 hsa-mir-21 Colorectal Neoplasms 22476768 Kaplan-Meier analysis proved that the miR-21 expression levels are correlated to shorter overall survival of CRC patients. 8041 hsa-mir-30a Breast Neoplasms 22476851 MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer. 8042 hsa-let-7c Prostatic Neoplasms 22479342 MicroRNA let-7c Is Downregulated in Prostate Cancer and Suppresses Prostate Cancer Growth. 8043 hsa-mir-195 Colorectal Neoplasms 22479426 The driving miRNAs were miR-195, miR-1280, miR-140-3p and miR-1246 in colorectal tumors. 8044 hsa-mir-1280 Colorectal Neoplasms 22479426 The driving miRNAs were miR-195, miR-1280, miR-140-3p and miR-1246 in colorectal tumors. 8045 hsa-mir-140 Colorectal Neoplasms 22479426 The driving miRNAs were miR-195, miR-1280, miR-140-3p and miR-1246 in colorectal tumors. 8046 hsa-mir-1246 Colorectal Neoplasms 22479426 The driving miRNAs were miR-195, miR-1280, miR-140-3p and miR-1246 in colorectal tumors. 8047 hsa-mir-23a Pancreatic Neoplasms 22479426 The driving miRNAs were miR-103, miR-23a and miR-15b in pancreatic cancers. 8048 hsa-mir-15b Pancreatic Neoplasms 22479426 The driving miRNAs were miR-103, miR-23a and miR-15b in pancreatic cancers. 8049 hsa-mir-103a-1 Pancreatic Neoplasms 22479426 The driving miRNAs were miR-103, miR-23a and miR-15b in pancreatic cancers. 8050 hsa-mir-103b-1 Pancreatic Neoplasms 22479426 The driving miRNAs were miR-103, miR-23a and miR-15b in pancreatic cancers. 8051 hsa-mir-103a-2 Pancreatic Neoplasms 22479426 The driving miRNAs were miR-103, miR-23a and miR-15b in pancreatic cancers. 8052 hsa-mir-103b-2 Pancreatic Neoplasms 22479426 The driving miRNAs were miR-103, miR-23a and miR-15b in pancreatic cancers. 8053 hsa-mir-34a Glioma 22479456 miR-34a Repression in Proneural Malignant Gliomas Upregulates Expression of Its Target PDGFRA and Promotes Tumorigenesis. 8054 hsa-mir-141 Hepatitis B 22479552 MicroRNA-141 Represses HBV Replication by Targeting PPARA 8055 hsa-mir-26a-1 Cholangiocarcinoma 22484120 MicroRNA-26a Promotes Cholangiocarcinoma Growth by Activating beta-catenin. 8056 hsa-mir-26a-2 Cholangiocarcinoma 22484120 MicroRNA-26a Promotes Cholangiocarcinoma Growth by Activating beta-catenin. 8057 hsa-mir-22 Lung Neoplasms 22484852 miR-22 suppresses lung cancer cell progression through post-transcriptional regulation of ErbB3. 8058 hsa-mir-21 Lymphoma, Non-Hodgkin 22487708 B-cell activation induced microRNA-21 is elevated in circulating B cells preceding the diagnosis of AIDS-related non-Hodgkin lymphomas. 8059 hsa-mir-1258 Carcinoma, Non-Small-Cell Lung 22488243 The miR-1258 regulates the expression level of HPSE to influence the morbidity and metastasis of NSCLC. 8060 hsa-mir-151a Breast Neoplasms 22489664 miR-151-5p upregulation may suppress metastasis in primary breast tumors. 8061 hsa-mir-151b Breast Neoplasms 22489664 miR-151-5p upregulation may suppress metastasis in primary breast tumors. 8062 hsa-mir-143 Glioblastoma 22490015 Serial selection for invasiveness increases expression of miR-143/miR-145 in glioblastoma cell lines. 8063 hsa-mir-145 Glioblastoma 22490015 Serial selection for invasiveness increases expression of miR-143/miR-145 in glioblastoma cell lines. 8064 hsa-mir-135a-1 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma 8065 hsa-mir-135a-2 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma 8066 hsa-mir-708 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma 8067 hsa-mir-150 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma 8068 hsa-mir-363 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma 8069 hsa-mir-184 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma 8070 hsa-mir-342 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma 8071 hsa-mir-574 Colorectal Neoplasms 22490519 miR-574-5p negatively regulates Qki6/7 to impact β-catenin/Wnt signalling and the development of colorectal cancer. 8072 hsa-mir-130a Prolactinoma 22490835 down-regulated 8073 hsa-mir-199b Prolactinoma 22490835 miR-199b-3p: down-regulated 8074 hsa-mir-200b Prolactinoma 22490835 down-regulated 8075 hsa-mir-125b-1 Prolactinoma 22490835 down-regulated 8076 hsa-mir-125b-2 Prolactinoma 22490835 down-regulated 8077 hsa-mir-342 Prolactinoma 22490835 miR-342-3p: up-regulated 8078 hsa-mir-432 Prolactinoma 22490835 up-regulated 8079 hsa-mir-23b Prolactinoma 22490835 up-regulated 8080 hsa-mir-493 Prolactinoma 22490835 up-regulated 8081 hsa-mir-493 Prolactinoma 22490835 miR-493*: up-regulated 8082 hsa-mir-664 Prolactinoma 22490835 miR-664*: up-regulated 8083 hsa-mir-107 Head and Neck Neoplasms 22491216 Lipid-based Nanoparticle Delivery of Pre-miR-107 Inhibits the Tumorigenicity of Head and Neck Squamous Cell Carcinoma. 8084 hsa-mir-193b Carcinoma, Non-Small-Cell Lung 22491710 MicroRNA-193b modulates proliferation, migration, and invasion of non-small cell lung cancer cells. 8085 hsa-mir-22 Colorectal Neoplasms 22492279 The relative expression levels of miR-22 were significantly lower in colorectal cancer tissues than those in the normal adjacent mucosa, and low expression of miR-22 correlated with liver metastasis. Kaplan-Meier analysis indicated that patients with reduced miR-22 had a poor overall survival. 8086 hsa-mir-143 Carcinoma, Renal Cell 22492545 Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse. 8087 hsa-mir-145 Carcinoma, Renal Cell 22492545 Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse. 8088 hsa-mir-10b Carcinoma, Renal Cell 22492545 Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse. 8089 hsa-mir-195 Carcinoma, Renal Cell 22492545 Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse. 8090 hsa-mir-126 Carcinoma, Renal Cell 22492545 Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse. 8091 hsa-mir-127 Carcinoma, Renal Cell 22492545 miR-127-3p, miR-145, and miR-126 are significantly correlated with relapse-free survival of nonmetastatic RCC patients. 8092 hsa-mir-145 Carcinoma, Renal Cell 22492545 miR-127-3p, miR-145, and miR-126 are significantly correlated with relapse-free survival of nonmetastatic RCC patients. 8093 hsa-mir-126 Carcinoma, Renal Cell 22492545 miR-127-3p, miR-145, and miR-126 are significantly correlated with relapse-free survival of nonmetastatic RCC patients. 8094 hsa-mir-26a-1 Carcinoma, Renal Cell 22492545 Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse. 8095 hsa-mir-26a-2 Carcinoma, Renal Cell 22492545 Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse. 8096 hsa-mir-21 Glioblastoma 22492962 The levels of miR-10b and miR-21 are found significantly increased in the CSF (cerebrospinal fluid) of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions. 8097 hsa-mir-10b Glioblastoma 22492962 The levels of miR-10b and miR-21 are found significantly increased in the CSF (cerebrospinal fluid) of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions. 8098 hsa-mir-21 Breast Neoplasms 22492962 The levels of miR-10b and miR-21 are found significantly increased in the CSF (cerebrospinal fluid) of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions. 8099 hsa-mir-10b Breast Neoplasms 22492962 The levels of miR-10b and miR-21 are found significantly increased in the CSF (cerebrospinal fluid) of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions. 8100 hsa-mir-21 Lung Neoplasms 22492962 The levels of miR-10b and miR-21 are found significantly increased in the CSF (cerebrospinal fluid) of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions. 8101 hsa-mir-10b Lung Neoplasms 22492962 The levels of miR-10b and miR-21 are found significantly increased in the CSF (cerebrospinal fluid) of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions. 8102 hsa-mir-29a Leukemia, Myeloid, Acute 22493297 MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia. 8103 hsa-mir-142 Leukemia, Myeloid, Acute 22493297 MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia. 8104 hsa-mir-148a Carcinoma, Hepatocellular 22496917 miR-148a may play a central role in HBx/URG11 mediated HCC, and may be an early diagnostic marker and/or therapeutic target associated with this tumor type. 8105 hsa-mir-106b Neuroblastoma 22498172 Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells) 8106 hsa-mir-92a-1 Neuroblastoma 22498172 Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells) 8107 hsa-mir-92a-2 Neuroblastoma 22498172 Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells) 8108 hsa-mir-92b Neuroblastoma 22498172 Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells) 8109 hsa-mir-93 Neuroblastoma 22498172 Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells) 8110 hsa-mir-7-1 Neuroblastoma 22498172 Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells) 8111 hsa-mir-34a Neuroblastoma 22498172 Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells) 8112 hsa-mir-99a Neuroblastoma 22498172 Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells) 8113 hsa-mir-199a-1 Ovarian Neoplasms 22498306 MicroRNA-199a targets CD44 to suppress the tumorigenicity and multi-drug resistance of ovarian cancer-initiating cells. 8114 hsa-mir-199a-2 Ovarian Neoplasms 22498306 MicroRNA-199a targets CD44 to suppress the tumorigenicity and multi-drug resistance of ovarian cancer-initiating cells. 8115 hsa-mir-214 Carcinoma, Non-Small-Cell Lung 22502680 MicroRNA-214 Regulates the Acquired Resistance to Gefitinib via the PTEN/AKT Pathway in EGFR-mutant Cell Lines. 8116 hsa-mir-331 Prostatic Neoplasms 22505520 The authors experientially validated the miRNA-KLK interaction by transfecting miR-331-3p and miR-143 into a PCa cell line. 8117 hsa-mir-143 Prostatic Neoplasms 22505520 The authors experientially validated the miRNA-KLK interaction by transfecting miR-331-3p and miR-143 into a PCa cell line. 8118 hsa-mir-27a Prostatic Neoplasms 22505583 Androgen regulated processing of the oncomir MiR-27a, which targets Prohibitin in prostate cancer. 8119 hsa-mir-133a-1 Osteoporosis 22506038 miR-133a in circulating monocytes is a potential biomarker for postmenopausal osteoporosis. 8120 hsa-mir-133a-2 Osteoporosis 22506038 miR-133a in circulating monocytes is a potential biomarker for postmenopausal osteoporosis. 8121 hsa-mir-375 Breast Neoplasms 22508479 Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer. 8122 hsa-mir-21 Osteolysis 22508494 miR-21 Expression is related to particle-induced osteolysis pathogenesis. 8123 hsa-mir-126 Carcinoma, Non-Small-Cell Lung 22510476 miR-126 enhances the sensitivity of non-small cell lung cancer cells to anticancer agents by targeting vascular endothelial growth factor A. 8124 hsa-mir-31 Leukemia, Myelogenous, Chronic, BCR-ABL Positive 22511990 Downregulation of mir-31, mir-155, and mir-564 in chronic myeloid leukemia cells. 8125 hsa-mir-155 Leukemia, Myelogenous, Chronic, BCR-ABL Positive 22511990 Downregulation of mir-31, mir-155, and mir-564 in chronic myeloid leukemia cells. 8126 hsa-mir-564 Leukemia, Myelogenous, Chronic, BCR-ABL Positive 22511990 Downregulation of mir-31, mir-155, and mir-564 in chronic myeloid leukemia cells. 8127 hsa-mir-125b-1 Lung Diseases, Interstitial 22512273 (miR-125b-5p, miR-128, miR-30e, and miR-20b) were significantly changed, both in the lung tissue and in plasma, and exhibited mainstream (MS) exposure duration-dependent pathological changes in the lung. 8128 hsa-mir-125b-2 Lung Diseases, Interstitial 22512273 (miR-125b-5p, miR-128, miR-30e, and miR-20b) were significantly changed, both in the lung tissue and in plasma, and exhibited mainstream (MS) exposure duration-dependent pathological changes in the lung. 8129 hsa-mir-128-1 Lung Diseases, Interstitial 22512273 (miR-125b-5p, miR-128, miR-30e, and miR-20b) were significantly changed, both in the lung tissue and in plasma, and exhibited mainstream (MS) exposure duration-dependent pathological changes in the lung. 8130 hsa-mir-128-2 Lung Diseases, Interstitial 22512273 (miR-125b-5p, miR-128, miR-30e, and miR-20b) were significantly changed, both in the lung tissue and in plasma, and exhibited mainstream (MS) exposure duration-dependent pathological changes in the lung. 8131 hsa-mir-30e Lung Diseases, Interstitial 22512273 (miR-125b-5p, miR-128, miR-30e, and miR-20b) were significantly changed, both in the lung tissue and in plasma, and exhibited mainstream (MS) exposure duration-dependent pathological changes in the lung. 8132 hsa-mir-20b Lung Diseases, Interstitial 22512273 (miR-125b-5p, miR-128, miR-30e, and miR-20b) were significantly changed, both in the lung tissue and in plasma, and exhibited mainstream (MS) exposure duration-dependent pathological changes in the lung. 8133 hsa-mir-15b Kidney Failure, Chronic 22512691 Reduced Circulating miR-15b Is Correlated with Phosphate Metabolism in Patients with End-Stage Renal Disease on Maintenance Hemodialysis. 8134 hsa-mir-200c Endometrial Neoplasms 22514717 The expression levels of miR-200c (P<0.0001) and miR-205 (P<0.0001) were significantly increased in endometrial tumors compared to normal tissues. Kaplan-Meier survival analysis revealed that high levels of miR-205 expression were associated with poor patient overall survival. 8135 hsa-mir-205 Endometrial Neoplasms 22514717 The expression levels of miR-200c (P<0.0001) and miR-205 (P<0.0001) were significantly increased in endometrial tumors compared to normal tissues. Kaplan-Meier survival analysis revealed that high levels of miR-205 expression were associated with poor patient overall survival. 8136 hsa-mir-204 Carcinoma, Renal Cell 22516261 VHL-Regulated MiR-204 Suppresses Tumor Growth through Inhibition of LC3B-Mediated Autophagy in Renal Clear Cell Carcinoma. 8137 hsa-mir-301a Demyelinating Diseases 22517757 Both in vivo and in vitro, myelin antigen stimulation resulted in significant up-regulation of miR-301a, miR-21, and miR-155. miR-301a has a role in regulating the function of myelin-reactive T-helper type 17 cells, supporting a role for miR-301a as candidate for therapeutic targets for controlling of autoimmune demyelination. 8138 hsa-mir-21 Demyelinating Diseases 22517757 Both in vivo and in vitro, myelin antigen stimulation resulted in significant up-regulation of miR-301a, miR-21, and miR-155. 8139 hsa-mir-155 Demyelinating Diseases 22517757 Both in vivo and in vitro, myelin antigen stimulation resulted in significant up-regulation of miR-301a, miR-21, and miR-155. 8140 hsa-mir-21 Esophageal Neoplasms 22519435 Circulating miR-21 and miR-375 could be reliable prognostic markers for ESCC. 8141 hsa-mir-375 Esophageal Neoplasms 22519435 Circulating miR-21 and miR-375 could be reliable prognostic markers for ESCC. 8142 hsa-mir-298 Breast Neoplasms 22521303 Increased expression of P-glycoprotein and doxorubicin chemoresistance of metastatic breast cancer is regulated by miR-298. 8143 hsa-mir-34a Lymphoma, Large B-Cell, Diffuse 22522790 Systemic microRNA-34a delivery induces apoptosis and abrogates growth of diffuse large B-cell lymphoma in vivo. 8144 hsa-mir-125b-1 Breast Neoplasms 22523546 miR-125b was significantly associated with therapeutic response, exhibiting higher expression level in non-responsive patients. 8145 hsa-mir-125b-2 Breast Neoplasms 22523546 miR-125b was significantly associated with therapeutic response, exhibiting higher expression level in non-responsive patients. 8146 hsa-mir-10a Breast Neoplasms 22524830 The BC patients showed an up-regulation in miRNAs (mir-155, mir-10,mir-21 and mir-373) 8147 hsa-mir-10b Breast Neoplasms 22524830 The BC patients showed an up-regulation in miRNAs (mir-155, mir-10,mir-21 and mir-373) 8148 hsa-mir-126 Breast Neoplasms 22524830 down regulation in mir-17p, mir-126, mir-335, mir-30b 8149 hsa-mir-155 Breast Neoplasms 22524830 The BC patients showed an up-regulation in miRNAs (mir-155, mir-10,mir-21 and mir-373) 8150 hsa-mir-17 Breast Neoplasms 22524830 down regulation in mir-17p, mir-126, mir-335, mir-30b 8151 hsa-mir-21 Breast Neoplasms 22524830 The BC patients showed an up-regulation in miRNAs (mir-155, mir-10,mir-21 and mir-373) 8152 hsa-mir-30b Breast Neoplasms 22524830 down regulation in mir-17p, mir-126, mir-335, mir-30b 8153 hsa-mir-335 Breast Neoplasms 22524830 down regulation in mir-17p, mir-126, mir-335, mir-30b 8154 hsa-mir-373 Breast Neoplasms 22524830 The BC patients showed an up-regulation in miRNAs (mir-155, mir-10,mir-21 and mir-373) 8155 hsa-mir-126 Diabetes Mellitus 22525256 Downregulation of microRNA-126 in endothelial progenitor cells from diabetes patients, impairs their functional properties, via target gene Spred-1. 8156 hsa-mir-205 Melanoma 22525428 Loss of microRNA-205 expression is associated with melanoma progression. 8157 hsa-mir-183 Osteosarcoma 22525461 Down-regulation of miR-183 promotes migration and invasion of osteosarcoma by targeting Ezrin. 8158 hsa-mir-675 Osteoarthritis 22527881 Proinflammatory cytokines IL-1beta and TNF-alpha downregulated COL2A1, H19, and miR-675 significantly without close statistical correlation. 8159 hsa-mir-21 Glioblastoma 22528454 MicroRNA-21 inhibitor sensitizes human glioblastoma U251 stem cells to chemotherapeutic drug temozolomide. 8160 hsa-mir-10b Carcinoma, Hepatocellular 22528944 MicroRNA-10b promotes migration and invasion through CADM1 in human hepatocellular carcinoma cells. 8161 hsa-mir-3151 Leukemia, Myeloid, Acute 22529287 miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia. 8162 hsa-mir-143 Colorectal Neoplasms 22533346 MicroRNA-143 targets MACC1 to inhibit cell invasion and migration in colorectal cancer. 8163 hsa-mir-181a-1 Coronary Artery Disease 22535975 Decreased miR-181a Expression in Monocytes of Obese Patients Is Associated with the Occurrence of Metabolic Syndrome and Coronary Artery Disease. 8164 hsa-mir-181a-2 Coronary Artery Disease 22535975 Decreased miR-181a Expression in Monocytes of Obese Patients Is Associated with the Occurrence of Metabolic Syndrome and Coronary Artery Disease. 8165 hsa-mir-129-1 Carcinoma, Hepatocellular 22536440 VCP/p97, down-regulated by microRNA-129-5p, could regulate the progression of hepatocellular carcinoma. 8166 hsa-mir-129-2 Carcinoma, Hepatocellular 22536440 VCP/p97, down-regulated by microRNA-129-5p, could regulate the progression of hepatocellular carcinoma. 8167 hsa-mir-938 Stomach Neoplasms 22537748 Genetic polymorphisms of IL17A ((rs2275913 (-197 G > A), rs3748067 (*1249 C > T)) and pri-microRNA-938 (pri-miR-938, rs2505901 (T > C).), targeting IL17A 3'-UTR, influence susceptibility to gastric cancer. 8168 hsa-mir-181b-1 Stomach Neoplasms 22539488 MicroRNA-181b targets cAMP responsive element binding protein 1 in gastric adenocarcinomas. 8169 hsa-mir-181b-2 Stomach Neoplasms 22539488 MicroRNA-181b targets cAMP responsive element binding protein 1 in gastric adenocarcinomas. 8170 hsa-mir-106b Carcinoma, Basal Cell 22540308 upregulated in the tumor center 8171 hsa-mir-125a Carcinoma, Basal Cell 22540308 miR-125a-5p is upregulated in the tumor center 8172 hsa-mir-139 Carcinoma, Basal Cell 22540308 miR-139-5p is downregulated in the tumor center 8173 hsa-mir-140 Carcinoma, Basal Cell 22540308 miR-140-3p is downregulated in the tumor center 8174 hsa-mir-145 Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8175 hsa-mir-17 Carcinoma, Basal Cell 22540308 upregulated in the tumor center 8176 hsa-mir-181c Carcinoma, Basal Cell 22540308 miR-181c and miR-181c* are upregulated in the tumor center 8177 hsa-mir-181d Carcinoma, Basal Cell 22540308 upregulated in the tumor center 8178 hsa-mir-182 Carcinoma, Basal Cell 22540308 upregulated in the tumor center 8179 hsa-mir-18a Carcinoma, Basal Cell 22540308 upregulated in the tumor center 8180 hsa-mir-18b Carcinoma, Basal Cell 22540308 upregulated in the tumor center 8181 hsa-mir-19b-1 Carcinoma, Basal Cell 22540308 miR-19b is upregulated in the tumor center 8182 hsa-mir-19b-1 Carcinoma, Basal Cell 22540308 miR-19b-1* upregulated in the tumor center 8183 hsa-mir-19b-2 Carcinoma, Basal Cell 22540308 miR-19b is upregulated in the tumor center 8184 hsa-mir-2861 Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8185 hsa-mir-29c Carcinoma, Basal Cell 22540308 miR-29c and miR-29c* are downregulated in the tumor center 8186 hsa-mir-3196 Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8187 hsa-mir-455 Carcinoma, Basal Cell 22540308 miR-455-5p and miR-455-3p are upregulated in the tumor center 8188 hsa-mir-542 Carcinoma, Basal Cell 22540308 miR-542 is upregulated in the tumor center 8189 hsa-mir-572 Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8190 hsa-mir-638 Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8191 hsa-mir-93 Carcinoma, Basal Cell 22540308 upregulated in the tumor center 8192 hsa-mir-378a Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8193 hsa-mir-378b Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8194 hsa-mir-378c Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8195 hsa-mir-378d-1 Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8196 hsa-mir-378d-2 Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8197 hsa-mir-378e Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8198 hsa-mir-378f Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8199 hsa-mir-378g Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8200 hsa-mir-378h Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8201 hsa-mir-378i Carcinoma, Basal Cell 22540308 downregulated in the tumor center 8202 hsa-mir-214 Cholangiocarcinoma 22540680 Downregulated miR-214 contributes to intrahepatic cholangiocarcinoma metastasis by targeting Twist. 8203 hsa-mir-21 Lymphoma 22541087 The expression of miR-21 in plasma of lymphoma patient group significantly correlated with their serum LDH level. The expressions of miR-21 and miR-210 in plasma of previously untreated lymphoma patient group were higher than those of the patients treated for 6 or more courses 8204 hsa-mir-210 Lymphoma 22541087 The expression of miR-21 in plasma of lymphoma patient group significantly correlated with their serum LDH level. The expressions of miR-21 and miR-210 in plasma of previously untreated lymphoma patient group were higher than those of the patients treated for 6 or more courses 8205 hsa-mir-206 Rhabdomyosarcoma 22541669 miR-206 integrates multiple components of differentiation pathways to control the transition from growth to differentiation in rhabdomyosarcoma cells. 8206 hsa-mir-378a Carcinoma, Renal Cell 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. 8207 hsa-mir-378b Carcinoma, Renal Cell 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. 8208 hsa-mir-378c Carcinoma, Renal Cell 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. 8209 hsa-mir-378d-1 Carcinoma, Renal Cell 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. 8210 hsa-mir-378d-2 Carcinoma, Renal Cell 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. 8211 hsa-mir-378e Carcinoma, Renal Cell 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. 8212 hsa-mir-378f Carcinoma, Renal Cell 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. 8213 hsa-mir-378g Carcinoma, Renal Cell 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. 8214 hsa-mir-378h Carcinoma, Renal Cell 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. 8215 hsa-mir-378i Carcinoma, Renal Cell 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. 8216 hsa-mir-30b Mouth Neoplasms 22542163 Amplification and up-regulation of microRNA-30b in oral squamous cell cancers. 8217 hsa-mir-142 Endometrial Neoplasms 22543862 miR-142-5p: Increased expression after Progesterone Treatment. 8218 hsa-mir-146b Endometrial Neoplasms 22543862 miR-146b-5p: Increased expression after Progesterone Treatment. 8219 hsa-mir-193b Endometrial Neoplasms 22543862 Decreased expression after Progesterone Treatment. 8220 hsa-mir-21 Endometrial Neoplasms 22543862 Increased expression after Progesterone Treatment. 8221 hsa-mir-29c Endometrial Neoplasms 22543862 Decreased expression after Progesterone Treatment. 8222 hsa-mir-625 Endometrial Neoplasms 22543862 miR-625*: Increased expression after Progesterone Treatment. 8223 hsa-mir-633 Endometrial Neoplasms 22543862 Decreased expression after Progesterone Treatment. 8224 hsa-mir-21 Breast Neoplasms 22547075 DNA damage induces NF-kB-dependent microRNA-21 upregulation and promotes breast cancer cell invasion. 8225 hsa-mir-143 Colorectal Neoplasms 22549179 Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer. 8226 hsa-mir-142 Lupus Erythematosus, Systemic 22549634 Decreased miR-142-3p/5p expression causes CD4(+) T cell activation and B cell hyperstimulation in systemic lupus erythematosus. 8227 hsa-mir-127 Thyroid Neoplasms 22550943 MTC (medullary thyroid carcinomas) and CCH (C-cell hyperplasia) were both characterized by a significant overexpression of the miRNA. 8228 hsa-mir-154 Thyroid Neoplasms 22550943 MTC (medullary thyroid carcinomas) and CCH (C-cell hyperplasia) were both characterized by a significant overexpression of the miRNA. 8229 hsa-mir-183 Thyroid Neoplasms 22550943 MTC (medullary thyroid carcinomas) and CCH (C-cell hyperplasia) were both characterized by a significant overexpression of the miRNA. 8230 hsa-mir-21 Thyroid Neoplasms 22550943 MTC (medullary thyroid carcinomas) and CCH (C-cell hyperplasia) were both characterized by a significant overexpression of the miRNA. 8231 hsa-mir-370 Thyroid Neoplasms 22550943 MTC (medullary thyroid carcinomas) and CCH (C-cell hyperplasia) were both characterized by a significant overexpression of the miRNA. 8232 hsa-mir-375 Thyroid Neoplasms 22550943 MTC (medullary thyroid carcinomas) and CCH (C-cell hyperplasia) were both characterized by a significant overexpression of the miRNA. 8233 hsa-mir-9-1 Thyroid Neoplasms 22550943 MTC (medullary thyroid carcinomas) and CCH (C-cell hyperplasia) were both characterized by a significant overexpression of the miRNA, miR-9*. 8234 hsa-mir-9-2 Thyroid Neoplasms 22550943 MTC (medullary thyroid carcinomas) and CCH (C-cell hyperplasia) were both characterized by a significant overexpression of the miRNA, miR-9*. 8235 hsa-mir-9-3 Thyroid Neoplasms 22550943 MTC (medullary thyroid carcinomas) and CCH (C-cell hyperplasia) were both characterized by a significant overexpression of the miRNA, miR-9*. 8236 hsa-mir-323a Thyroid Neoplasms 22550943 MTC (medullary thyroid carcinomas) and CCH (C-cell hyperplasia) were both characterized by a significant overexpression of the miRNA. 8237 hsa-mir-323b Thyroid Neoplasms 22550943 MTC (medullary thyroid carcinomas) and CCH (C-cell hyperplasia) were both characterized by a significant overexpression of the miRNA. 8238 hsa-let-7g Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. 8239 hsa-mir-138-1 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. 8240 hsa-mir-138-2 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. 8241 hsa-mir-15a Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. 8242 hsa-mir-16-1 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. 8243 hsa-mir-16-2 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. 8244 hsa-mir-181a-1 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. 8245 hsa-mir-191 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. 8246 hsa-mir-933 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. 8247 hsa-mir-181a-2 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. 8248 hsa-mir-126 Carcinoma, Hepatocellular 22552153 recurrence-related in hepatocellular carcinoma 8249 hsa-mir-147a Carcinoma, Hepatocellular 22552153 recurrence-related in hepatocellular carcinoma 8250 hsa-mir-19a Carcinoma, Hepatocellular 22552153 recurrence-related in hepatocellular carcinoma 8251 hsa-mir-223 Carcinoma, Hepatocellular 22552153 recurrence-related in hepatocellular carcinoma 8252 hsa-mir-24-1 Carcinoma, Hepatocellular 22552153 recurrence-related in hepatocellular carcinoma 8253 hsa-mir-24-2 Carcinoma, Hepatocellular 22552153 recurrence-related in hepatocellular carcinoma 8254 hsa-mir-708 Prostatic Neoplasms 22552290 miRNA-708 control of CD44+ prostate cancer initiating cells. 8255 hsa-mir-27a Breast Neoplasms 22553354 Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer. 8256 hsa-mir-520a Colorectal Neoplasms 22553375 A 3' untranslated region (UTR) mutation was also shown to be associated with increased sensitivity to saracatinib and have a reduced affinity for miR-520a and miR-525a. 8257 hsa-mir-21 Colorectal Neoplasms 22553926 EGF/Ras efficiently induces the miR-21 primary transcript, but this does not rapidly and simply translate into higher mature miR-21 levels. 8258 hsa-mir-205 Prostatic Neoplasms 22555458 miR-205 regulates basement membrane deposition in human prostate. 8259 hsa-mir-106b Leiomyoma 22556343 miR-93/106b and Their Host Gene, MCM7, Are Differentially Expressed in Leiomyomas and Functionally Target F3 and IL-8. 8260 hsa-mir-93 Leiomyoma 22556343 miR-93/106b and Their Host Gene, MCM7, Are Differentially Expressed in Leiomyomas and Functionally Target F3 and IL-8. 8261 hsa-mir-155 Asthma 22558995 The decreased expression level of miR-155 is correlated to asthma disease severity. 8262 hsa-mir-19a Uterine Cervical Neoplasms 22561557 MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5. 8263 hsa-mir-19b-1 Uterine Cervical Neoplasms 22561557 MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5. 8264 hsa-mir-19b-2 Uterine Cervical Neoplasms 22561557 MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5. 8265 hsa-mir-34a Colorectal Neoplasms 22562822 microRNA-34a, microRNA-155 and microRNA-200c overexpression in human colorectal cancer. 8266 hsa-mir-92a-1 Breast Neoplasms 22563438 Downregulation of miR-92a is associated with aggressive breast cancer features and increased tumour macrophage infiltration. 8267 hsa-mir-92a-2 Breast Neoplasms 22563438 Downregulation of miR-92a is associated with aggressive breast cancer features and increased tumour macrophage infiltration. 8268 hsa-mir-9-1 Neuroblastoma 22564723 microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells. 8269 hsa-mir-9-2 Neuroblastoma 22564723 microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells. 8270 hsa-mir-9-3 Neuroblastoma 22564723 microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells. 8271 hsa-mir-93 Stomach Neoplasms 22567743 miR-93 is highly elevated in gastric cancer, especially in advanced and metastasized gastric cancer, suggesting miR-93 may play critical roles in carcinogenesis of gastric cancer. Overexpression of miR-93 can serve as a novel prognostic marker for gastric cancer. 8272 hsa-mir-34a Glioma 22568628 MicroRNA-34a Suppresses Cell Proliferation and Induces Apoptosis in U87 Glioma Stem Cells. 8273 hsa-mir-221 Asthma 22572970 Inhibition of miRNA-221 Suppresses the Airway Inflammation in Asthma. 8274 hsa-mir-708 Carcinoma, Non-Small-Cell Lung 22573352 Increased miR-708 expression in NSCLC and its association with poor survival in lung adenocarcinoma from never smokers. 8275 hsa-mir-10b Breast Neoplasms 22573479 Targeting of syndecan-1 by microRNA miR-10b promotes breast cancer cell motility and invasiveness via a Rho-GTPase- and E-cadherin-dependent mechanism. 8276 hsa-mir-15a Colonic Neoplasms 22574716 Vector-based miR-15a/16-1 plasmid inhibits colon cancer growth in vivo. 8277 hsa-mir-16-1 Colonic Neoplasms 22574716 Vector-based miR-15a/16-1 plasmid inhibits colon cancer growth in vivo. 8278 hsa-mir-205 Breast Neoplasms 22578566 Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer. 8279 hsa-mir-139 Colorectal Neoplasms 22580051 MiR-139 inhibits invasion and metastasis of colorectal cancer by targeting the type I insulin-like growth factor receptor. 8280 hsa-mir-502 Colonic Neoplasms 22580605 Inhibition of autophagy and tumor growth in colon cancer by miR-502. 8281 hsa-mir-34a Glioblastoma 22580610 miR-34a functions as a tumor suppressor modulating EGFR in glioblastoma multiforme. 8282 hsa-mir-181a-1 Stomach Neoplasms 22581522 MicroRNA-181a promotes gastric cancer by negatively regulating tumor suppressor KLF6. 8283 hsa-mir-181a-2 Stomach Neoplasms 22581522 MicroRNA-181a promotes gastric cancer by negatively regulating tumor suppressor KLF6. 8284 hsa-mir-93 Colorectal Neoplasms 22581829 MicroRNA-93 inhibits tumor growth and early relapse of human colorectal cancer by affecting genes involved in the cell cycle. 8285 hsa-mir-182 Precursor Cell Lymphoblastic Leukemia-Lymphoma 22582938 Aberrant microRNA-182 expression is associated with glucocorticoid resistance in lymphoblastic malignancies. 8286 hsa-mir-17 Carcinoma, Hepatocellular 22583011 miR-17-5p was significantly upregulated in HCCs. HCC with metastasis had higher miR-17-5p levels than that without metastasis. 8287 hsa-mir-16-1 Breast Neoplasms 22583478 Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development. 8288 hsa-let-7a-1 Colorectal Neoplasms 22584434 High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease. 8289 hsa-let-7a-2 Colorectal Neoplasms 22584434 High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease. 8290 hsa-let-7a-3 Colorectal Neoplasms 22584434 High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease. 8291 hsa-mir-608 Breast Neoplasms 22586447 Polymorphism rs4919510:C>G in mature sequence of human microRNA-608 contributes to the risk of HER2-positive breast cancer but not other subtypes. 8292 hsa-mir-122 Coronary Artery Disease 22587332 Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease. 8293 hsa-mir-370 Coronary Artery Disease 22587332 Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease. 8294 hsa-mir-122 Hyperlipidemias 22587332 Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease. 8295 hsa-mir-370 Hyperlipidemias 22587332 Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease. 8296 hsa-mir-92a-1 Carcinoma, Hepatocellular 22587342 Oxidative DNA damage correlates with cell immortalization and mir-92 expression in hepatocellular carcinoma. 8297 hsa-mir-103a-1 Breast Neoplasms 22588912 The serum levels of miR-103 expression were significantly higher in the cancer patients than in the healthy control group (P<0.01). In the cancer patients, high miR-103 expression was significantly correlated to advanced clinical stage (P<0.05) and lymph node metastasis (P<0.05). 8298 hsa-mir-103a-2 Breast Neoplasms 22588912 The serum levels of miR-103 expression were significantly higher in the cancer patients than in the healthy control group (P<0.01). In the cancer patients, high miR-103 expression was significantly correlated to advanced clinical stage (P<0.05) and lymph node metastasis (P<0.05). 8299 hsa-mir-103b-1 Breast Neoplasms 22588912 The serum levels of miR-103 expression were significantly higher in the cancer patients than in the healthy control group (P<0.01). In the cancer patients, high miR-103 expression was significantly correlated to advanced clinical stage (P<0.05) and lymph node metastasis (P<0.05). 8300 hsa-mir-103b-2 Breast Neoplasms 22588912 The serum levels of miR-103 expression were significantly higher in the cancer patients than in the healthy control group (P<0.01). In the cancer patients, high miR-103 expression was significantly correlated to advanced clinical stage (P<0.05) and lymph node metastasis (P<0.05). 8301 hsa-mir-381 Lung Neoplasms 22592211 MicroRNA-381 represses ID1 and is deregulated in lung adenocarcinoma. 8302 hsa-mir-145 Breast Neoplasms 22592534 MiR-145 inhibits tumor angiogenesis and growth by N-RAS and VEGF. 8303 hsa-mir-122 Hepatitis C 22593164 Expression of MicroRNA miR-122 Facilitates an Efficient Replication in Nonhepatic Cells upon Infection with Hepatitis C Virus. 8304 hsa-mir-107 Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 8305 hsa-mir-103a-1 Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 8306 hsa-mir-103a-2 Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 8307 hsa-mir-103b-1 Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 8308 hsa-mir-103b-2 Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 8309 hsa-mir-423 Breast Neoplasms 22593246 A genetic variant (rs6505162:A>C) located in miR-423 is associated with reduced breast cancer risk. 8310 hsa-mir-34b Carcinoma, Non-Small-Cell Lung 22593438 Overexpression of miR-34b significantly reduced cell survival at lower than 4 Gy radiation doses. 8311 hsa-mir-125b-1 Laryngeal Neoplasms 22605671 Downregulation 8312 hsa-mir-125b-2 Laryngeal Neoplasms 22605671 Downregulation 8313 hsa-mir-145 Laryngeal Neoplasms 22605671 Downregulation 8314 hsa-mir-205 Laryngeal Neoplasms 22605671 Upregulation 8315 hsa-mir-21 Laryngeal Neoplasms 22605671 Upregulation 8316 hsa-mir-708 Laryngeal Neoplasms 22605671 Upregulation 8317 hsa-mir-93 Laryngeal Neoplasms 22605671 Upregulation 8318 hsa-mir-608 Colorectal Neoplasms 22606253 rs4919510 in hsa-mir-608 is associated with outcome but not risk of colorectal cancer. 8319 hsa-mir-155 Lymphoma, Large B-Cell, Diffuse 22609116 miR-155 Regulates the PI3K-AKT pathway in diffuse large B-cell lymphoma. 8320 hsa-mir-101-1 Carcinoma, Renal Cell 22609199 The enhancer of zeste homolog 2 (EZH2), a potential therapeutic target, is regulated by miR-101 in renal cancer cells. 8321 hsa-mir-101-2 Carcinoma, Renal Cell 22609199 The enhancer of zeste homolog 2 (EZH2), a potential therapeutic target, is regulated by miR-101 in renal cancer cells. 8322 hsa-mir-181a-1 Leukemia, Lymphocytic, Chronic, B-Cell 22610076 miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes. 8323 hsa-mir-181a-2 Leukemia, Lymphocytic, Chronic, B-Cell 22610076 miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes. 8324 hsa-mir-181b-1 Leukemia, Lymphocytic, Chronic, B-Cell 22610076 miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes. 8325 hsa-mir-181b-2 Leukemia, Lymphocytic, Chronic, B-Cell 22610076 miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes. 8326 hsa-mir-214 Carcinoma, Hepatocellular 22613005 MicroRNA-214 downregulation contributes to tumor angiogenesis by inducing secretion of the hepatoma-derived growth factor in human hepatoma. 8327 hsa-mir-221 Stomach Neoplasms 22613407 MiR-221 was up-regulated in 88% (81/92) of gastric cancer tissue samples compared with their paired adjacent nontumour tissue samples. High expression of miR-221 showed a significant correlation with advanced tumour-node-metastasis stage, local invasion and lymphatic metastasis. 8328 hsa-mir-106b Myocardial Infarction 22613985 MiR-106b and MiR-15b modulate apoptosis and angiogenesis in myocardial infarction. 8329 hsa-mir-7-1 Stomach Neoplasms 22614005 MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor. 8330 hsa-mir-7-2 Stomach Neoplasms 22614005 MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor. 8331 hsa-mir-7-3 Stomach Neoplasms 22614005 MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor. 8332 hsa-mir-27a Glioma 22614734 Lentiviral expression of anti-microRNAs targeting miR-27a inhibits proliferation and invasiveness of U87 glioma cells. 8333 hsa-mir-130a Ovarian Neoplasms 22614869 Altered microRNA expression in cisplatin-resistant ovarian cancer cells and upregulation of miR-130a associated with MDR1/P-glycoprotein-mediated drug resistance. 8334 hsa-mir-625 Mesothelioma 22617246 Increased circulating miR-625-3p is a potential biomarker for patients with malignant pleural mesothelioma. 8335 hsa-mir-30a Leukemia, Myelogenous, Chronic, BCR-ABL Positive 22617440 microRNA 30A promotes autophagy in response to cancer therapy. 8336 hsa-mir-21 Breast Neoplasms 22618231 Regulatory interplay between miR-21, JAG1 and 17beta-estradiol (E2) in breast cancer cells. 8337 hsa-mir-34a Breast Neoplasms 22623155 MiR-34a inhibits proliferation and migration of breast cancer through down-regulation of Bcl-2 and SIRT1. 8338 hsa-mir-10b Carcinoma, Renal Cell 22623952 The expression levels of miR-10b, miR-139-5p, miR-130b and miR-199b-5p could determine the status of ccRCC metastasis. 8339 hsa-mir-130b Carcinoma, Renal Cell 22623952 The expression levels of miR-10b, miR-139-5p, miR-130b and miR-199b-5p could determine the status of ccRCC metastasis. 8340 hsa-mir-139 Carcinoma, Renal Cell 22623952 The expression levels of miR-10b, miR-139-5p, miR-130b and miR-199b-5p could determine the status of ccRCC metastasis. 8341 hsa-mir-195 Carcinoma, Renal Cell 22623952 The expression levels of miR-10b, miR-139-5p, miR-130b and miR-199b-5p could determine the status of ccRCC metastasis. 8342 hsa-mir-199b Carcinoma, Renal Cell 22623952 The expression levels of miR-10b, miR-139-5p, miR-130b and miR-199b-5p could determine the status of ccRCC metastasis. 8343 hsa-mir-34a Carcinoma, Squamous Cell 22624980 miR-34a is downregulated in cis-diamminedichloroplatinum treated sinonasal squamous cell carcinoma patients with poor prognosis. 8344 hsa-mir-23a Colorectal Neoplasms 22628407 miR-23a promotes the transition from indolent to invasive colorectal cancer. 8345 hsa-mir-155 Carcinoma, Hepatocellular 22629365 High expression levels of miR-155, miR-15a, miR-432, miR-486-3p, miR-15b and miR-30b were significantly associated with recurrence-free. 8346 hsa-mir-15a Carcinoma, Hepatocellular 22629365 High expression levels of miR-155, miR-15a, miR-432, miR-486-3p, miR-15b and miR-30b were significantly associated with recurrence-free. 8347 hsa-mir-15b Carcinoma, Hepatocellular 22629365 High expression levels of miR-155, miR-15a, miR-432, miR-486-3p, miR-15b and miR-30b were significantly associated with recurrence-free. 8348 hsa-mir-30b Carcinoma, Hepatocellular 22629365 High expression levels of miR-155, miR-15a, miR-432, miR-486-3p, miR-15b and miR-30b were significantly associated with recurrence-free. 8349 hsa-mir-432 Carcinoma, Hepatocellular 22629365 High expression levels of miR-155, miR-15a, miR-432, miR-486-3p, miR-15b and miR-30b were significantly associated with recurrence-free. 8350 hsa-mir-486 Carcinoma, Hepatocellular 22629365 High expression levels of miR-155, miR-15a, miR-432, miR-486-3p, miR-15b and miR-30b were significantly associated with recurrence-free. 8351 hsa-mir-34a Head and Neck Neoplasms 22629428 Dysregulation of microRNA-34a expression in head and neck squamous cell carcinoma promotes tumor growth and tumor angiogenesis. 8352 hsa-mir-21 Glioma 22630347 MicroRNA-21 expression is regulated by β-catenin/STAT3 pathway and promotes glioma cell invasion by direct targeting RECK. 8353 hsa-mir-205 Breast Neoplasms 22631664 miR-205 and miR-342 may be used as potential biomarkers for diagnosis of triple negative breast cancer. 8354 hsa-mir-342 Breast Neoplasms 22631664 miR-205 and miR-342 may be used as potential biomarkers for diagnosis of triple negative breast cancer. 8355 hsa-mir-10a Uterine Cervical Neoplasms 22634495 MicroRNA-10a targets CHL1 and promotes cell growth, migration and invasion in human cervical cancer cells. 8356 hsa-mir-200a Pancreatic Neoplasms 22637745 Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer. 8357 hsa-mir-200b Pancreatic Neoplasms 22637745 Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer. 8358 hsa-mir-200c Pancreatic Neoplasms 22637745 Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer. 8359 hsa-mir-21 Breast Neoplasms 22638884 miR-21 was significantly overexpressed in human solid cancerous serum relative to normal control (P < 0.001), and its sensitivity and specificity were significantly higher than the currently used tumor markers. 8360 hsa-mir-21 Esophageal Neoplasms 22638884 miR-21 was significantly overexpressed in human solid cancerous serum relative to normal control (P < 0.001), and its sensitivity and specificity were significantly higher than the currently used tumor markers. 8361 hsa-mir-21 Lung Neoplasms 22638884 miR-21 was significantly overexpressed in human solid cancerous serum relative to normal control (P < 0.001), and its sensitivity and specificity were significantly higher than the currently used tumor markers. 8362 hsa-mir-21 Colorectal Neoplasms 22638884 miR-21 was significantly overexpressed in human solid cancerous serum relative to normal control (P < 0.001), and its sensitivity and specificity were significantly higher than the currently used tumor markers. 8363 hsa-mir-21 Stomach Neoplasms 22638884 miR-21 was significantly overexpressed in human solid cancerous serum relative to normal control (P < 0.001), and its sensitivity and specificity were significantly higher than the currently used tumor markers. 8364 hsa-mir-499a Carcinoma, Hepatocellular 22641068 Histone Deacetylases Activate Hepatocyte Growth Factor Signaling by Repressing MicroRNA-449 in Hepatocellular Carcinoma Cells. 8365 hsa-mir-499b Carcinoma, Hepatocellular 22641068 Histone Deacetylases Activate Hepatocyte Growth Factor Signaling by Repressing MicroRNA-449 in Hepatocellular Carcinoma Cells. 8366 hsa-mir-133a-1 Esophageal Neoplasms 22641236 CD47 expression regulated by the miR-133a tumor suppressor is a novel prognostic marker in esophageal squamous cell carcinoma. 8367 hsa-mir-133a-2 Esophageal Neoplasms 22641236 CD47 expression regulated by the miR-133a tumor suppressor is a novel prognostic marker in esophageal squamous cell carcinoma. 8368 hsa-mir-181a-1 Colorectal Neoplasms 22641662 KRAS up-regulates the expression of miR-181a, miR-200c and miR-210 in a three-dimensional-specific manner in DLD-1 colorectal cancer cells. 8369 hsa-mir-181a-2 Colorectal Neoplasms 22641662 KRAS up-regulates the expression of miR-181a, miR-200c and miR-210 in a three-dimensional-specific manner in DLD-1 colorectal cancer cells. 8370 hsa-mir-200c Colorectal Neoplasms 22641662 KRAS up-regulates the expression of miR-181a, miR-200c and miR-210 in a three-dimensional-specific manner in DLD-1 colorectal cancer cells. 8371 hsa-mir-210 Colorectal Neoplasms 22641662 KRAS up-regulates the expression of miR-181a, miR-200c and miR-210 in a three-dimensional-specific manner in DLD-1 colorectal cancer cells. 8372 hsa-mir-139 Colorectal Neoplasms 22642900 Regulation of RAP1B by miR-139 suppresses human colorectal carcinoma cell proliferation. 8373 hsa-mir-21 Prostatic Neoplasms 22642976 miR-21 may acts as an oncomir by targeting RECK, a matrix metalloproteinase regulator, in prostate cancer. 8374 hsa-mir-100 Urinary Bladder Neoplasms 22644299 differential expression in urinary samples 8375 hsa-mir-1224 Urinary Bladder Neoplasms 22644299 differential expression in urinary samples 8376 hsa-mir-135b Urinary Bladder Neoplasms 22644299 differential expression in urinary samples 8377 hsa-mir-15a Urinary Bladder Neoplasms 22644299 differential expression in urinary samples 8378 hsa-mir-15b Urinary Bladder Neoplasms 22644299 differential expression in urinary samples 8379 hsa-mir-203 Urinary Bladder Neoplasms 22644299 differential expression in urinary samples 8380 hsa-mir-212 Urinary Bladder Neoplasms 22644299 differential expression in urinary samples 8381 hsa-mir-24-1 Urinary Bladder Neoplasms 22644299 differential expression in urinary samples 8382 hsa-mir-27b Urinary Bladder Neoplasms 22644299 differential expression in urinary samples 8383 hsa-mir-328 Urinary Bladder Neoplasms 22644299 differential expression in urinary samples 8384 hsa-mir-335 Glioma 22644918 Tumor microRNA-335 expression is associated with poor prognosis in human glioma. 8385 hsa-mir-107 Obesity 22645244 miR-107: a Toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes. 8386 hsa-mir-107 Diabetes Mellitus, Type 2 22645244 miR-107: a Toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes. 8387 hsa-mir-34a Colorectal Neoplasms 22648208 Circulating miR-34a levels are reduced in colorectal cancer. 8388 hsa-mir-146a Moyamoya Disease 22659075 Association of the miR-146aC>G, miR-196a2C>T, and miR-499A>G polymorphisms with moyamoya disease in the Korean population. 8389 hsa-mir-196a-2 Moyamoya Disease 22659075 Association of the miR-146aC>G, miR-196a2C>T, and miR-499A>G polymorphisms with moyamoya disease in the Korean population. 8390 hsa-mir-23b Inflammation 22660635 The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α. 8391 hsa-mir-31 Pulmonary Fibrosis 22661007 miR-31 is a negative regulator of fibrogenesis and pulmonary fibrosis. 8392 hsa-mir-219-1 Colorectal Neoplasms 22661538 The mir219-1:rs213210 showed consistent association with death in the training set, the replication set, and combined data set 8393 hsa-mir-608 Colorectal Neoplasms 22661538 In patients with stage III disease, mir608: rs4919510 was associated with increased risk for both recurrence and death. 8394 hsa-mir-92a-1 Scleroderma, Systemic 22661558 microRNA-92a expression in the sera and dermal fibroblasts increases in patients with scleroderma. 8395 hsa-mir-92a-2 Scleroderma, Systemic 22661558 microRNA-92a expression in the sera and dermal fibroblasts increases in patients with scleroderma. 8396 hsa-mir-9-1 Head and Neck Neoplasms 22664743 IRS-1 suppresses metastasis of head and neck cancer possibly through miR-9 8397 hsa-mir-9-2 Head and Neck Neoplasms 22664743 IRS-1 suppresses metastasis of head and neck cancer possibly through miR-9 8398 hsa-mir-9-3 Head and Neck Neoplasms 22664743 IRS-1 suppresses metastasis of head and neck cancer possibly through miR-9 8399 hsa-mir-1-1 Carcinoma, Hepatocellular 22664953 MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells. 8400 hsa-mir-1-2 Carcinoma, Hepatocellular 22664953 MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells. 8401 hsa-mir-499a Carcinoma, Hepatocellular 22664953 MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells. 8402 hsa-mir-499b Carcinoma, Hepatocellular 22664953 MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells. 8403 hsa-mir-210 Pancreatic Neoplasms 22672828 miR-210 expression in PC cells is induced by hypoxia through a HIF-1alpha-dependent pathway, but does not influence PC cell proliferation. 8404 hsa-mir-133a-1 Astrocytoma 22674182 Significantly decreased in grades II-IV patients. 8405 hsa-mir-133a-2 Astrocytoma 22674182 Significantly decreased in grades II-IV patients. 8406 hsa-mir-150 Astrocytoma 22674182 miR-150*:Significantly decreased in grades II-IV patients. 8407 hsa-mir-15b Astrocytoma 22674182 miR-15b*: Significantly decreased in grades II-IV patients. 8408 hsa-mir-197 Astrocytoma 22674182 Significantly decreased in grades II-IV patients. 8409 hsa-mir-23a Astrocytoma 22674182 Significantly decreased in grades II-IV patients. 8410 hsa-mir-497 Astrocytoma 22674182 Significantly decreased in grades II-IV patients. 8411 hsa-mir-548b Astrocytoma 22674182 miR-548b-5p: Significantly decreased in grades II-IV patients. 8412 hsa-mir-190a Meningioma 22674195 Downregulation of miR-29c-3p and miR-219-5p were found to be associated with advanced clinical stages of meningioma. Kaplan-Meier analysis showed that high expression of miR-190a and low expression of miR-29c-3p and miR-219-5p correlated significantly with higher recurrence rates in meningioma patients. 8413 hsa-mir-219-1 Meningioma 22674195 Downregulation of miR-29c-3p and miR-219-5p were found to be associated with advanced clinical stages of meningioma. Kaplan-Meier analysis showed that high expression of miR-190a and low expression of miR-29c-3p and miR-219-5p correlated significantly with higher recurrence rates in meningioma patients. 8414 hsa-mir-219-2 Meningioma 22674195 Downregulation of miR-29c-3p and miR-219-5p were found to be associated with advanced clinical stages of meningioma. Kaplan-Meier analysis showed that high expression of miR-190a and low expression of miR-29c-3p and miR-219-5p correlated significantly with higher recurrence rates in meningioma patients. 8415 hsa-mir-29c Meningioma 22674195 Downregulation of miR-29c-3p and miR-219-5p were found to be associated with advanced clinical stages of meningioma. Kaplan-Meier analysis showed that high expression of miR-190a and low expression of miR-29c-3p and miR-219-5p correlated significantly with higher recurrence rates in meningioma patients. 8416 hsa-mir-193b Aging 22674437 MicroRNA-199a-3p, microRNA-193b, and microRNA-320c are correlated to aging and regulate human cartilage metabolism. 8417 hsa-mir-199a-1 Aging 22674437 MicroRNA-199a-3p, microRNA-193b, and microRNA-320c are correlated to aging and regulate human cartilage metabolism. 8418 hsa-mir-199a-2 Aging 22674437 MicroRNA-199a-3p, microRNA-193b, and microRNA-320c are correlated to aging and regulate human cartilage metabolism. 8419 hsa-mir-320c-1 Aging 22674437 MicroRNA-199a-3p, microRNA-193b, and microRNA-320c are correlated to aging and regulate human cartilage metabolism. 8420 hsa-mir-320c-2 Aging 22674437 MicroRNA-199a-3p, microRNA-193b, and microRNA-320c are correlated to aging and regulate human cartilage metabolism. 8421 hsa-mir-361 Carcinoma, Non-Small-Cell Lung 22675530 Low levels of cell-free circulating miR-361-3p and miR-625* could be blood-based markers for discriminating malignant from benign lung tumors. 8422 hsa-mir-625 Carcinoma, Non-Small-Cell Lung 22675530 Low levels of cell-free circulating miR-361-3p and miR-625* could be blood-based markers for discriminating malignant from benign lung tumors. 8423 hsa-mir-297 Colorectal Neoplasms 22676135 miR-297 modulates multidrug resistance in human colorectal carcinoma by down-regulating MRP-2. 8424 hsa-mir-222 Colorectal Neoplasms 22677042 MiR-222 modulates multidrug resistance in human colorectal carcinoma by down-regulating ADAM-17. 8425 hsa-mir-625 Stomach Neoplasms 22677169 Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer by targeting ILK. 8426 hsa-mir-17 Colonic Neoplasms 22677902 miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer. 8427 hsa-mir-19a Colonic Neoplasms 22677902 miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer. 8428 hsa-mir-21 Colonic Neoplasms 22677902 miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer. 8429 hsa-mir-21 Breast Neoplasms 22678116 miR-21 is targeted by omega-3 polyunsaturated fatty acid to regulate breast tumor CSF-1 expression. 8430 hsa-mir-182 Carcinoma, Hepatocellular 22681717 MicroRNA-182 downregulates metastasis suppressor 1 and contributes to metastasis of hepatocellular carcinoma. 8431 hsa-mir-155 Leukemia, Myeloid, Acute 22681934 MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status. 8432 hsa-mir-424 Leukemia, Myeloid, Acute 22681934 MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status. 8433 hsa-mir-221 Glioma 22681957 High level of miR-221/222 confers increased cell invasion and poor prognosis in glioma. 8434 hsa-mir-222 Glioma 22681957 High level of miR-221/222 confers increased cell invasion and poor prognosis in glioma. 8435 hsa-mir-17 Osteosarcoma 22682620 up-regulated in osteosarcoma. 8436 hsa-mir-18a Osteosarcoma 22682620 up-regulated in osteosarcoma. 8437 hsa-mir-19a Osteosarcoma 22682620 up-regulated in osteosarcoma. 8438 hsa-mir-19b-1 Osteosarcoma 22682620 up-regulated in osteosarcoma. 8439 hsa-mir-20a Osteosarcoma 22682620 up-regulated in osteosarcoma. 8440 hsa-mir-92a-1 Osteosarcoma 22682620 up-regulated in osteosarcoma. 8441 hsa-mir-574 Stomach Neoplasms 22683180 miR-574-3p: Aberrant expression 8442 hsa-mir-126 Lupus Erythematosus, Systemic 22683424 miR-126 was specifically enriched only in the blood of the SLE patients 8443 hsa-let-7b Liver Neoplasms 22683924 Downregulation of HMGA2 by the pan-deacetylase inhibitor panobinostat is dependent on hsa-let-7b expression in liver cancer cell lines. 8444 hsa-mir-376a-1 Carcinoma, Hepatocellular 22684007 miR-376a suppresses proliferation and induces apoptosis in hepatocellular carcinoma. 8445 hsa-mir-376a-2 Carcinoma, Hepatocellular 22684007 miR-376a suppresses proliferation and induces apoptosis in hepatocellular carcinoma. 8446 hsa-mir-23a Colorectal Neoplasms 22684455 miR-23a, a critical regulator of "migR"ation and metastasis in colorectal cancer. 8447 hsa-mir-34a Glioma 22684560 MicroRNA-34a inhibits human brain glioma cell growth by down-regulation of Notch1. 8448 hsa-mir-34a Urinary Bladder Neoplasms 22684561 microRNA-34a inhibit cell migration and invasion of invasive urothelial bladder carcinoma by targeting Notch1. 8449 hsa-mir-15a Odontogenic Tumors 22684875 miR-15a/16-1 influences BCL2 expression in keratocystic odontogenic tumors. 8450 hsa-mir-16-1 Odontogenic Tumors 22684875 miR-15a/16-1 influences BCL2 expression in keratocystic odontogenic tumors. 8451 hsa-mir-16-2 Odontogenic Tumors 22684875 miR-15a/16-1 influences BCL2 expression in keratocystic odontogenic tumors. 8452 hsa-mir-590 Carcinoma, Hepatocellular 22684895 MicroRNA-590-5p regulates proliferation and invasion in human hepatocellular carcinoma cells by targeting TGF-beta RII. 8453 hsa-mir-200a Leiomyoma 22685266 miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5. 8454 hsa-mir-93 Breast Neoplasms 22685420 MicroRNA93 regulates proliferation and differentiation of normal and malignant breast stem cells. 8455 hsa-mir-21 Carcinoma, Renal Cell 22685542 microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion. 8456 hsa-mir-100 Pulmonary Disease, Chronic Obstructive 22686440 There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls. 8457 hsa-mir-20a Pulmonary Disease, Chronic Obstructive 22686440 There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls. 8458 hsa-mir-28 Pulmonary Disease, Chronic Obstructive 22686440 There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls. 8459 hsa-mir-34c Pulmonary Disease, Chronic Obstructive 22686440 There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls. 8460 hsa-mir-7-1 Pulmonary Disease, Chronic Obstructive 22686440 There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls. 8461 hsa-mir-7-2 Pulmonary Disease, Chronic Obstructive 22686440 There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls. 8462 hsa-mir-7-3 Pulmonary Disease, Chronic Obstructive 22686440 There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls. 8463 hsa-mir-21 Esophageal Neoplasms 22689922 Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer. 8464 hsa-mir-31 Esophageal Neoplasms 22689922 Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer. 8465 hsa-mir-125a Head and Neck Neoplasms 22690848 Differential expression 8466 hsa-mir-125b-1 Head and Neck Neoplasms 22690848 Differential expression 8467 hsa-mir-125b-2 Head and Neck Neoplasms 22690848 Differential expression 8468 hsa-mir-203 Head and Neck Neoplasms 22690848 Differential expression 8469 hsa-mir-21 Head and Neck Neoplasms 22690848 Differential expression 8470 hsa-mir-31 Head and Neck Neoplasms 22690848 Differential expression 8471 hsa-mir-143 Colonic Neoplasms 22691140 microRNA-143 down-regulates Hexokinase 2 in colon cancer cells. 8472 hsa-mir-181a-1 Breast Neoplasms 22692639 Decreased serum miR-181a is a potential new tool for breast cancer screening. 8473 hsa-mir-181a-2 Breast Neoplasms 22692639 Decreased serum miR-181a is a potential new tool for breast cancer screening. 8474 hsa-mir-125b-1 Breast Neoplasms 22693547 MicroRNA-125b induces metastasis by targeting STARD13 in MCF-7 and MDA-MB-231 breast cancer cells. 8475 hsa-mir-125b-2 Breast Neoplasms 22693547 MicroRNA-125b induces metastasis by targeting STARD13 in MCF-7 and MDA-MB-231 breast cancer cells. 8476 hsa-mir-30c-1 Breast Neoplasms 22701724 miR-30c overexpression inhibited proliferation of breast cancer cells.miR-30c binds the 3'UTR of KRAS transcripts and expression of pre-miR-30c down-regulated KRAS mRNA and protein. 8477 hsa-mir-30c-2 Breast Neoplasms 22701724 miR-30c overexpression inhibited proliferation of breast cancer cells.miR-30c binds the 3'UTR of KRAS transcripts and expression of pre-miR-30c down-regulated KRAS mRNA and protein. 8478 hsa-mir-34a Neuroblastoma 22703967 Inhibition of cyclin-dependent kinase 1-induced cell death in neuroblastoma cells through the microRNA-34a-MYCN-survivin pathway. 8479 hsa-mir-10b Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8480 hsa-mir-126 Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8481 hsa-mir-145 Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8482 hsa-mir-19a Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8483 hsa-mir-21 Urinary Bladder Neoplasms 22704449 High miR-21 expression correlated with worse overall patient survival (p = 0.0099). 8484 hsa-mir-221 Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8485 hsa-mir-296 Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8486 hsa-mir-378a Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8487 hsa-mir-378b Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8488 hsa-mir-378c Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8489 hsa-mir-378d-1 Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8490 hsa-mir-378d-2 Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8491 hsa-mir-378e Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8492 hsa-mir-378f Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8493 hsa-mir-378g Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8494 hsa-mir-378h Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8495 hsa-mir-378i Urinary Bladder Neoplasms 22704449 miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium. 8496 hsa-mir-7-1 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. 8497 hsa-mir-7-2 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. 8498 hsa-mir-7-3 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. 8499 hsa-mir-218-1 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. 8500 hsa-mir-218-2 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. 8501 hsa-mir-31 Esophageal Neoplasms 22706599 MicroRNA-31 modulates tumour sensitivity to radiation in oesophageal adenocarcinoma. 8502 hsa-mir-200c Cholangiocarcinoma 22707408 Inactivation of miR-200c resulted in an induction of EMT, whereas activation of miR-200c led to a reduction of EMT including a reduced cell migration and invasion in ICC cells. 8503 hsa-mir-21 Glioblastoma 22709411 MiR-21 Modulates hTERT Through a STAT3-Dependent Manner on Glioblastoma Cell Growth. 8504 hsa-mir-23b Prostatic Neoplasms 22710126 MicroRNA-23b downregulates peroxiredoxin III in human prostate cancer. 8505 hsa-mir-325 Pre-Eclampsia 22710575 The expression of hsa-miR-325 was downregulated in the case of PE. Changes in hsa-miR?325 expression in the case of pregnancy-related hypertensive disorders might affect the oxidative stress pathways and heat-shock protein production. 8506 hsa-mir-497 Colorectal Neoplasms 22710713 MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer. 8507 hsa-mir-632 Breast Neoplasms 22710984 Micro-RNA-632 downregulates DNAJB6 in breast cancer. 8508 hsa-mir-146a Stomach Neoplasms 22711166 microRNA-146a targets the L1 cell adhesion molecule and suppresses the metastatic potential of gastric cancer. 8509 hsa-mir-146a Nasopharyngeal Neoplasms 22711332 A single nucleotide polymorphism (rs2910164) in microRNA-146a is associated with the risk for nasopharyngeal carcinoma. 8510 hsa-mir-125b-1 Glioblastoma 22711523 miR-125b expression plays an essential role in the invasion of glioblastoma CD133-positive cells but not CD133-negative cells. 8511 hsa-mir-125b-2 Glioblastoma 22711523 miR-125b expression plays an essential role in the invasion of glioblastoma CD133-positive cells but not CD133-negative cells. 8512 hsa-mir-199a-1 Carcinoma, Hepatocellular 22713463 Cisplatin-induced downregulation of miR-199a-5p increases drug resistance by activating autophagy in HCC cell. 8513 hsa-mir-199a-2 Carcinoma, Hepatocellular 22713463 Cisplatin-induced downregulation of miR-199a-5p increases drug resistance by activating autophagy in HCC cell. 8514 hsa-mir-203 Breast Neoplasms 22713668 MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells. 8515 hsa-mir-21 Melanoma 22716245 microRNA-21 is upregulated in malignant melanoma and influences apoptosis of melanocytic cells. 8516 hsa-mir-29b-1 Pre-Eclampsia 22716646 MicroRNA-29b contributes to pre-eclampsia through its effects on apoptosis, invasion and angiogenesis of trophoblast cells. 8517 hsa-mir-29b-2 Pre-Eclampsia 22716646 MicroRNA-29b contributes to pre-eclampsia through its effects on apoptosis, invasion and angiogenesis of trophoblast cells. 8518 hsa-mir-204 Nerve Sheath Neoplasms 22718995 MicroRNA-204 critically regulates carcinogenesis in malignant peripheral nerve sheath tumors. 8519 hsa-let-7b Prostatic Neoplasms 22719071 downregulated in prostate cancer stem/progenitor cell. 8520 hsa-mir-106a Prostatic Neoplasms 22719071 downregulated in prostate cancer stem/progenitor cell. 8521 hsa-mir-141 Prostatic Neoplasms 22719071 downregulated in prostate cancer stem/progenitor cell. 8522 hsa-mir-34a Prostatic Neoplasms 22719071 downregulated in prostate cancer stem/progenitor cell. 8523 hsa-mir-452 Prostatic Neoplasms 22719071 upregulated in prostate cancer stem/progenitor cell. 8524 hsa-mir-301a Prostatic Neoplasms 22719071 upregulated in prostate cancer stem/progenitor cell. 8525 hsa-mir-301b Prostatic Neoplasms 22719071 upregulated in prostate cancer stem/progenitor cell. 8526 hsa-mir-1-1 Myocardial Infarction 22719221 Increased miR-1 and decreased miR-126 in plasma from patients with AMI after the onset of symptoms compared with healthy subjects were found. 8527 hsa-mir-1-2 Myocardial Infarction 22719221 Increased miR-1 and decreased miR-126 in plasma from patients with AMI after the onset of symptoms compared with healthy subjects were found. 8528 hsa-mir-126 Myocardial Infarction 22719221 Increased miR-1 and decreased miR-126 in plasma from patients with AMI after the onset of symptoms compared with healthy subjects were found. 8529 hsa-mir-31 Leukoplakia, Oral 22719913 Upregulation of miR-31* is negatively associated with recurrent/newly formed oral leukoplakia. 8530 hsa-mir-122 Sepsis 22719975 Serum miR-223, miR-15a, miR-16, miR-122, miR-193*, and miR-483-5p were significantly differentially expressed. 8531 hsa-mir-15a Sepsis 22719975 Serum miR-223, miR-15a, miR-16, miR-122, miR-193*, and miR-483-5p were significantly differentially expressed. 8532 hsa-mir-16-1 Sepsis 22719975 Serum miR-223, miR-15a, miR-16, miR-122, miR-193*, and miR-483-5p were significantly differentially expressed. 8533 hsa-mir-16-2 Sepsis 22719975 Serum miR-223, miR-15a, miR-16, miR-122, miR-193*, and miR-483-5p were significantly differentially expressed. 8534 hsa-mir-193a Sepsis 22719975 Serum miR-223, miR-15a, miR-16, miR-122, miR-193*, and miR-483-5p were significantly differentially expressed. 8535 hsa-mir-223 Sepsis 22719975 Serum miR-223, miR-15a, miR-16, miR-122, miR-193*, and miR-483-5p were significantly differentially expressed. 8536 hsa-mir-483 Sepsis 22719975 Serum miR-223, miR-15a, miR-16, miR-122, miR-193*, and miR-483-5p were significantly differentially expressed. 8537 hsa-mir-195 Alzheimer Disease 22721728 MicroRNA-195 downregulates Alzheimer's disease amyloid-beta production by targeting BACE1. 8538 hsa-let-7d Glioblastoma 22722712 miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract). 8539 hsa-mir-137 Glioblastoma 22722712 miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract). 8540 hsa-mir-145 Glioblastoma 22722712 miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract). 8541 hsa-mir-153-1 Glioblastoma 22722712 miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract). 8542 hsa-mir-153-2 Glioblastoma 22722712 miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract). 8543 hsa-mir-181b-1 Glioblastoma 22722712 miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract). 8544 hsa-mir-181b-2 Glioblastoma 22722712 miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract). 8545 hsa-mir-708 Sarcoma, Ewing 22723308 EWS/FLI1 Regulates EYA3 in Ewing Sarcoma via Modulation of miRNA-708, Resulting in Increased Cell Survival and Chemoresistance. 8546 hsa-mir-125b-1 Leukemia, Lymphocytic, Chronic, B-Cell 22723551 The downregulation of miR-125b in chronic lymphocytic leukemias leads to metabolic adaptation of cells to a transformed state. 8547 hsa-mir-125b-2 Leukemia, Lymphocytic, Chronic, B-Cell 22723551 The downregulation of miR-125b in chronic lymphocytic leukemias leads to metabolic adaptation of cells to a transformed state. 8548 hsa-mir-196b Glioblastoma 22723849 Upregulation of miR-196b confers a poor prognosis in glioblastoma patients via inducing a proliferative phenotype. 8549 hsa-mir-137 Breast Neoplasms 22723937 MiR-137 targets estrogen-related receptor alpha and impairs the proliferative and migratory capacity of breast cancer cells. 8550 hsa-mir-337 Carcinoma, Non-Small-Cell Lung 22723956 miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers. 8551 hsa-mir-17 Uterine Cervical Neoplasms 22730212 MiR-17-5p targets TP53INP1 and regulates cell proliferation and apoptosis of cervical cancer cells. 8552 hsa-mir-153-1 Alzheimer Disease 22733824 MicroRNA-153 physiologically inhibits expression of amyloid-beta precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients. 8553 hsa-mir-153-2 Alzheimer Disease 22733824 MicroRNA-153 physiologically inhibits expression of amyloid-beta precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients. 8554 hsa-mir-200c Colorectal Neoplasms 22735571 MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis. 8555 hsa-mir-31 Lupus Erythematosus, Systemic 22736314 microRNA-31 is a novel regulator contributing to impaired IL-2 production in T cells from patients with systemic lupus erythematosus. 8556 hsa-mir-138-1 Nasopharyngeal Neoplasms 22739938 MiR-138 suppressed nasopharyngeal carcinoma growth and tumorigenesis by targeting the CCND1 oncogene. 8557 hsa-mir-138-2 Nasopharyngeal Neoplasms 22739938 MiR-138 suppressed nasopharyngeal carcinoma growth and tumorigenesis by targeting the CCND1 oncogene. 8558 hsa-mir-23b Glioblastoma 22745829 miRNA expression profiling in migrating glioblastoma cells: regulation of cell migration and invasion by miR-23b via targeting of Pyk2. 8559 hsa-mir-513a-1 Lung Neoplasms 22749944 miR-513a-3p sensitizes human lung adenocarcinoma cells to chemotherapy by targeting GSTP1. 8560 hsa-mir-513a-2 Lung Neoplasms 22749944 miR-513a-3p sensitizes human lung adenocarcinoma cells to chemotherapy by targeting GSTP1. 8561 hsa-mir-410 Glioma 22750473 MiR-410 regulates MET to influence the proliferation and invasion of glioma. 8562 hsa-mir-34a Glioblastoma 22750848 microRNA Regulatory Network Inference Identifies miR-34a as a Novel Regulator of TGF-beta Signaling in Glioblastoma. 8563 hsa-mir-29a Breast Neoplasms 22751119 Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4. 8564 hsa-mir-29b-2 Breast Neoplasms 22751119 Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4. 8565 hsa-mir-29c Breast Neoplasms 22751119 Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4. 8566 hsa-mir-29b-1 Breast Neoplasms 22751119 Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4. 8567 hsa-mir-99a Mouth Neoplasms 22751686 Downregulation of microRNA 99a in oral squamous cell carcinomas contributes to the growth and survival of oral cancer cells. 8568 hsa-mir-23a Lung Neoplasms 22752005 MiR-23a regulates TGF-beta-induced epithelial-mesenchymal transition by targeting E-cadherin in lung cancer cells. 8569 hsa-mir-21 Glioblastoma 22753745 MicroRNA-21 inhibition enhances in vitro chemosensitivity of temozolomide-resistant glioblastoma cells. 8570 hsa-mir-21 Mouth Neoplasms 22761427 Keratinization-associated miR-7 and miR-21 Regulate Tumor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal Motifs (RECK) in Oral Cancer. 8571 hsa-mir-7-1 Mouth Neoplasms 22761427 Keratinization-associated miR-7 and miR-21 Regulate Tumor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal Motifs (RECK) in Oral Cancer. 8572 hsa-mir-7-2 Mouth Neoplasms 22761427 Keratinization-associated miR-7 and miR-21 Regulate Tumor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal Motifs (RECK) in Oral Cancer. 8573 hsa-mir-7-3 Mouth Neoplasms 22761427 Keratinization-associated miR-7 and miR-21 Regulate Tumor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal Motifs (RECK) in Oral Cancer. 8574 hsa-mir-9-1 Breast Neoplasms 22761433 MicroRNA-9 Inhibition of Cell Proliferation and Identification of Novel miR-9 Targets by Transcriptome Profiling in Breast Cancer Cells. 8575 hsa-mir-9-2 Breast Neoplasms 22761433 MicroRNA-9 Inhibition of Cell Proliferation and Identification of Novel miR-9 Targets by Transcriptome Profiling in Breast Cancer Cells. 8576 hsa-mir-9-3 Breast Neoplasms 22761433 MicroRNA-9 Inhibition of Cell Proliferation and Identification of Novel miR-9 Targets by Transcriptome Profiling in Breast Cancer Cells. 8577 hsa-mir-499a Carcinoma, Squamous Cell 22761899 This study determined that a significant association of miRNA499 with CC genotype, as compared to the subjects with TT genotype, had a higher risk of oral squamous cell carcinoma. 8578 hsa-mir-499b Carcinoma, Squamous Cell 22761899 This study determined that a significant association of miRNA499 with CC genotype, as compared to the subjects with TT genotype, had a higher risk of oral squamous cell carcinoma. 8579 hsa-mir-145 Colonic Neoplasms 22766504 MiR-145 regulates PAK4 via the MAPK pathway and exhibits an antitumor effect in human colon cells. 8580 hsa-mir-1-1 Colorectal Neoplasms 22766685 Silencing of miR-1-1 and miR-133a-2 cluster expression by DNA hypermethylation in colorectal cancer. 8581 hsa-mir-133a-1 Colorectal Neoplasms 22766685 Silencing of miR-1-1 and miR-133a-2 cluster expression by DNA hypermethylation in colorectal cancer. 8582 hsa-mir-133a-2 Colorectal Neoplasms 22766685 Silencing of miR-1-1 and miR-133a-2 cluster expression by DNA hypermethylation in colorectal cancer. 8583 hsa-mir-10b Glioma 22766763 Co-inhibition of microRNA-10b and microRNA-21 exerts synergistic inhibition on the proliferation and invasion of human glioma cells. 8584 hsa-mir-21 Glioma 22766763 Co-inhibition of microRNA-10b and microRNA-21 exerts synergistic inhibition on the proliferation and invasion of human glioma cells. 8585 hsa-mir-182 Endometrial Neoplasms 22766795 In distinguishing endometrial endometrial carcinoma from complex atypical hyperplasia, the composite panel of four miRNAs (miR-182, 183, 200a, 200c) produced 95% sensitivity and 91% specificity. 8586 hsa-mir-183 Endometrial Neoplasms 22766795 In distinguishing endometrial endometrial carcinoma from complex atypical hyperplasia, the composite panel of four miRNAs (miR-182, 183, 200a, 200c) produced 95% sensitivity and 91% specificity. 8587 hsa-mir-200a Endometrial Neoplasms 22766795 In distinguishing endometrial endometrial carcinoma from complex atypical hyperplasia, the composite panel of four miRNAs (miR-182, 183, 200a, 200c) produced 95% sensitivity and 91% specificity. 8588 hsa-mir-200c Endometrial Neoplasms 22766795 In distinguishing endometrial endometrial carcinoma from complex atypical hyperplasia, the composite panel of four miRNAs (miR-182, 183, 200a, 200c) produced 95% sensitivity and 91% specificity. 8589 hsa-mir-138-1 Carcinoma, Renal Cell 22766839 Tumor suppressive microRNA-138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma. 8590 hsa-mir-138-2 Carcinoma, Renal Cell 22766839 Tumor suppressive microRNA-138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma. 8591 hsa-mir-218-1 Glioblastoma 22766851 MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1. 8592 hsa-mir-218-2 Glioblastoma 22766851 MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1. 8593 hsa-mir-650 Carcinoma, Hepatocellular 22767438 Upregulation of miR-650 is correlated with down-regulation of ING4 and progression of hepatocellular carcinoma. 8594 hsa-mir-125b-1 Myotonic Dystrophy 22768114 miR-125b-5p: decreased levels compared to controls 8595 hsa-mir-125b-2 Myotonic Dystrophy 22768114 miR-125b-5p: decreased levels compared to controls 8596 hsa-mir-146b Myotonic Dystrophy 22768114 higher levels compared to controls 8597 hsa-mir-193a Myotonic Dystrophy 22768114 miR-193a-3p: decreased levels compared to controls 8598 hsa-mir-193b Myotonic Dystrophy 22768114 miR-193b-3p: decreased levels compared to controls 8599 hsa-mir-208a Myotonic Dystrophy 22768114 miR-146b-5p: higher levels compared to controls 8600 hsa-mir-221 Myotonic Dystrophy 22768114 higher levels compared to controls 8601 hsa-mir-34a Myotonic Dystrophy 22768114 miR-34a-5p: higher levels compared to controls 8602 hsa-mir-34b Myotonic Dystrophy 22768114 miR-34b-3p: higher levels compared to controls 8603 hsa-mir-34c Myotonic Dystrophy 22768114 miR-34c-5p: higher levels compared to controls 8604 hsa-mir-378a Myotonic Dystrophy 22768114 miR-378a-3p: decreased levels compared to controls 8605 hsa-mir-381 Myotonic Dystrophy 22768114 higher levels compared to controls 8606 hsa-mir-7-1 Urinary Bladder Neoplasms 22768238 A microRNA-7 binding site polymorphism (1010A/G) in HOXB5 leads to differential gene expression in bladder cancer. 8607 hsa-mir-7-2 Urinary Bladder Neoplasms 22768238 A microRNA-7 binding site polymorphism (1010A/G) in HOXB5 leads to differential gene expression in bladder cancer. 8608 hsa-mir-7-3 Urinary Bladder Neoplasms 22768238 A microRNA-7 binding site polymorphism (1010A/G) in HOXB5 leads to differential gene expression in bladder cancer. 8609 hsa-mir-125a Carcinoma, Hepatocellular 22768249 Ectopic expression of MiR-125a inhibits the proliferation and metastasis of hepatocellular carcinoma by targeting MMP11 and VEGF. 8610 hsa-mir-21 Cholangiocarcinoma 22770403 PTEN and PDCD4 are bona fide targets of microRNA-21 in human cholangiocarcinoma. 8611 hsa-mir-29a Multiple Sclerosis 22772450 miR-29ab Deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias That Is Dysregulated in Multiple Sclerosis. 8612 hsa-mir-29b-1 Multiple Sclerosis 22772450 miR-29ab Deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias That Is Dysregulated in Multiple Sclerosis. 8613 hsa-mir-29b-2 Multiple Sclerosis 22772450 miR-29ab Deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias That Is Dysregulated in Multiple Sclerosis. 8614 hsa-mir-92a-1 Colorectal Neoplasms 22772712 Overexpression of miR-92a correlates with tumor metastasis and poor prognosis in patients with colorectal cancer. 8615 hsa-mir-93 Carcinoma, Hepatocellular 22773266 Downregulation of MiR-93 Expression Reduces Cell Proliferation and Clonogenicity of HepG2 Cells. 8616 hsa-mir-27b Dyslipidemias 22777896 MicroRNA-27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia. 8617 hsa-let-7e Lung Diseases, Interstitial 22782705 downregulated 8618 hsa-mir-142 Lung Diseases, Interstitial 22782705 miR-142-5p: downregulated 8619 hsa-mir-142 Lung Diseases, Interstitial 22782705 miR-191*: downregulated 8620 hsa-mir-19a Lung Diseases, Interstitial 22782705 downregulated 8621 hsa-mir-668 Lung Diseases, Interstitial 22782705 upregulated 8622 hsa-mir-92b Lung Diseases, Interstitial 22782705 upregulated 8623 hsa-mir-125b-1 Carcinoma, Squamous Cell 22782903 MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration, and Invasion. 8624 hsa-mir-125b-2 Carcinoma, Squamous Cell 22782903 MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration, and Invasion. 8625 hsa-mir-15a Myocardial Ischemia 22783320 MicroRNA-15a/b are up-regulated in response to myocardial ischemia/reperfusion injury. 8626 hsa-mir-15a Reperfusion Injury 22783320 MicroRNA-15a/b are up-regulated in response to myocardial ischemia/reperfusion injury. 8627 hsa-mir-15b Myocardial Ischemia 22783320 MicroRNA-15a/b are up-regulated in response to myocardial ischemia/reperfusion injury. 8628 hsa-mir-15b Reperfusion Injury 22783320 MicroRNA-15a/b are up-regulated in response to myocardial ischemia/reperfusion injury. 8629 hsa-mir-103a-1 Endometrial Neoplasms 22783422 microRNA-103 regulates the growth and invasion of endometrial cancer cells through the downregulation of tissue inhibitor of metalloproteinase 3. 8630 hsa-mir-103a-2 Endometrial Neoplasms 22783422 microRNA-103 regulates the growth and invasion of endometrial cancer cells through the downregulation of tissue inhibitor of metalloproteinase 3. 8631 hsa-mir-103b-1 Endometrial Neoplasms 22783422 microRNA-103 regulates the growth and invasion of endometrial cancer cells through the downregulation of tissue inhibitor of metalloproteinase 3. 8632 hsa-mir-103b-2 Endometrial Neoplasms 22783422 microRNA-103 regulates the growth and invasion of endometrial cancer cells through the downregulation of tissue inhibitor of metalloproteinase 3. 8633 hsa-mir-494 Cholangiocarcinoma 22785131 Coordinated effects of microRNA-494 induce G/M arrest in human cholangiocarcinoma. 8634 hsa-mir-20a Prostatic Neoplasms 22785209 CX43 expression is suppressed by miR-20a in the progression of human prostate cancer. 8635 hsa-mir-21 Stomach Neoplasms 22792096 miR-21 Is a Promising Novel Biomarker for Lymph Node Metastasis in Patients with Gastric Cancer. 8636 hsa-mir-340 Neuroblastoma 22797059 miR-340 is upregulated by demethylation of an upstream genomic region that occurs during the process of neuroblastoma cell differentiation induced by all-trans retinoic acid (ATRA). 8637 hsa-mir-125b-1 Melanoma 22797068 MicroRNA miR-125b controls melanoma progression by direct regulation of c-Jun protein expression. 8638 hsa-mir-125b-2 Melanoma 22797068 MicroRNA miR-125b controls melanoma progression by direct regulation of c-Jun protein expression. 8639 hsa-mir-155 Breast Neoplasms 22797073 Mutant p53 drives invasion in breast tumors through up-regulation of miR-155. 8640 hsa-mir-193b Prostatic Neoplasms 22797075 CFTR suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer. 8641 hsa-mir-200a Thyroid Neoplasms 22797360 The miR-200 family regulates the epithelial-mesenchymal transition induced by EGF/EGFR in anaplastic thyroid cancer cells. 8642 hsa-mir-200b Thyroid Neoplasms 22797360 The miR-200 family regulates the epithelial-mesenchymal transition induced by EGF/EGFR in anaplastic thyroid cancer cells. 8643 hsa-mir-200c Thyroid Neoplasms 22797360 The miR-200 family regulates the epithelial-mesenchymal transition induced by EGF/EGFR in anaplastic thyroid cancer cells. 8644 hsa-mir-21 Esophageal Neoplasms 22799367 Serum miR-21 expression in ESCC samples was significantly higher than in paired cancer-free samples (P <0.05). Metastasis was associated with mir-21 expression in serum (P <0.05), ESCC patients with metastasis having 8.4-fold higher serum miR-21 concentrations than healthy controls. 8645 hsa-mir-195 Breast Neoplasms 22800791 The levels of miR-195 in the breast cancer with histological high grade, tumor size of T3-4, lymph nodal involvement or vessel invasion were significantly down-regulated, compared with those of patients with histological low grade (Z = -2.271, P = 0.023), tumor size of T1-2 (Z = -2.687, P = 0.007), no lymph node metastasis (Z = -1.967, P = 0.049) and vessel invasion (Z = -2.432, P = 0.015). 8646 hsa-mir-10a Uterine Cervical Neoplasms 22801550 differentially expressed 8647 hsa-mir-193b Uterine Cervical Neoplasms 22801550 differentially expressed 8648 hsa-mir-203 Uterine Cervical Neoplasms 22801550 differentially expressed 8649 hsa-mir-20b Uterine Cervical Neoplasms 22801550 differentially expressed 8650 hsa-mir-338 Uterine Cervical Neoplasms 22801550 differentially expressed 8651 hsa-mir-345 Uterine Cervical Neoplasms 22801550 differentially expressed 8652 hsa-mir-34b Uterine Cervical Neoplasms 22801550 differentially expressed 8653 hsa-mir-34c Uterine Cervical Neoplasms 22801550 differentially expressed 8654 hsa-mir-424 Uterine Cervical Neoplasms 22801550 differentially expressed 8655 hsa-mir-9-1 Uterine Cervical Neoplasms 22801550 differentially expressed 8656 hsa-mir-9-2 Uterine Cervical Neoplasms 22801550 differentially expressed 8657 hsa-mir-9-3 Uterine Cervical Neoplasms 22801550 differentially expressed 8658 hsa-mir-512-1 Uterine Cervical Neoplasms 22801550 differentially expressed 8659 hsa-mir-512-2 Uterine Cervical Neoplasms 22801550 differentially expressed 8660 hsa-mir-518a-1 Uterine Cervical Neoplasms 22801550 differentially expressed 8661 hsa-mir-518a-2 Uterine Cervical Neoplasms 22801550 differentially expressed 8662 hsa-mir-335 Stomach Neoplasms 22802949 A high frequency recurrence and poor survival were observed in GC cases with high level of hsa-miR-335 (P<0.001). 8663 hsa-mir-200b Colorectal Neoplasms 22804917 In KRAS mutated tumours increased miR-200b and decreased miR-143 expression were associated with a good progression-free survival . 8664 hsa-mir-1256 Prostatic Neoplasms 22805767 Epigenetic deregulation of miR-29a and miR-1256 by isoflavone contributes to the inhibition of prostate cancer cell growth and invasion. 8665 hsa-mir-29a Prostatic Neoplasms 22805767 Epigenetic deregulation of miR-29a and miR-1256 by isoflavone contributes to the inhibition of prostate cancer cell growth and invasion. 8666 hsa-mir-125b-1 Carcinoma, Non-Small-Cell Lung 22806310 Circulating miR-125b is a novel biomarker for screening non-small-cell lung cancer and predicts poor prognosis. 8667 hsa-mir-125b-2 Carcinoma, Non-Small-Cell Lung 22806310 Circulating miR-125b is a novel biomarker for screening non-small-cell lung cancer and predicts poor prognosis. 8668 hsa-mir-21 Lung Neoplasms 22806311 miR-21 induces cell cycle at S phase and modulates cell proliferation by down-regulating hMSH2 in lung cancer. 8669 hsa-let-7a-1 Breast Neoplasms 22808086 Lin28 Mediates Paclitaxel Resistance by Modulating p21, Rb and Let-7a miRNA in Breast Cancer Cells. 8670 hsa-let-7a-2 Breast Neoplasms 22808086 Lin28 Mediates Paclitaxel Resistance by Modulating p21, Rb and Let-7a miRNA in Breast Cancer Cells. 8671 hsa-let-7a-3 Breast Neoplasms 22808086 Lin28 Mediates Paclitaxel Resistance by Modulating p21, Rb and Let-7a miRNA in Breast Cancer Cells. 8672 hsa-mir-224 Breast Neoplasms 22809510 MicroRNA-224 targets RKIP to control cell invasion and expression of metastasis genes in human breast cancer cells. 8673 hsa-mir-34a Leukemia, Myeloid, Acute 22810507 Clinically, low miR-34a expression and TP53 alterations predicted for chemotherapy resistance and inferior outcome. Notably, in TP53(unaltered) CK-AML, high miR-34a expression predicted for inferior overall survival (OS), whereas in TP53(biallelic altered) CK-AML, high miR-34a expression pointed to better OS. 8674 hsa-mir-21 Head and Neck Neoplasms 22811001 The expression level of miR-21 was significantly up-regulated in plasma samples obtained from HNSCC patients (p? 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation. 9034 hsa-mir-146b Atrial Fibrillation 22944230 MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation. 9035 hsa-mir-155 Atrial Fibrillation 22944230 MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation. 9036 hsa-mir-193a Atrial Fibrillation 22944230 MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation. 9037 hsa-mir-193b Atrial Fibrillation 22944230 MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation. 9038 hsa-mir-19a Atrial Fibrillation 22944230 MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation. 9039 hsa-mir-19b-1 Atrial Fibrillation 22944230 MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation. 9040 hsa-mir-19b-2 Atrial Fibrillation 22944230 MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation. 9041 hsa-mir-223 Atrial Fibrillation 22944230 MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation. 9042 hsa-mir-486 Atrial Fibrillation 22944230 MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation. 9043 hsa-mir-519b Atrial Fibrillation 22944230 MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation. 9044 hsa-mir-125b-1 Myelodysplastic Syndromes 22944560 Myelodysplastic syndrome with a t(2;11)(p21;q23-24) and translocation breakpoint close to miR-125b-1. 9045 hsa-mir-31 Melanoma 22948084 Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma. 9046 hsa-mir-143 Prostatic Neoplasms 22948942 miR-143 and miR-145 inhibit stem cell characteristics of PC-3 prostate cancer cells. 9047 hsa-mir-145 Prostatic Neoplasms 22948942 miR-143 and miR-145 inhibit stem cell characteristics of PC-3 prostate cancer cells. 9048 hsa-mir-146a Breast Neoplasms 22949171 MicroRNA-146a suppresses metastatic activity in brain metastasis. 9049 hsa-mir-205 Prostatic Neoplasms 22949650 Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. 9050 hsa-mir-141 Breast Neoplasms 22952344 CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05). 9051 hsa-mir-200a Breast Neoplasms 22952344 CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05). 9052 hsa-mir-200b Breast Neoplasms 22952344 CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05). 9053 hsa-mir-200c Breast Neoplasms 22952344 CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05). 9054 hsa-mir-203 Breast Neoplasms 22952344 CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05). 9055 hsa-mir-210 Breast Neoplasms 22952344 CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05). 9056 hsa-mir-375 Breast Neoplasms 22952344 CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05). 9057 hsa-mir-138-1 Urinary Bladder Neoplasms 22954303 Decreasing miR-138 increased the cisplatin sensitivity in half of the cell lines and increasing miR-27a and miR-642 generally increased cisplatin sensitivity. 9058 hsa-mir-138-2 Urinary Bladder Neoplasms 22954303 Decreasing miR-138 increased the cisplatin sensitivity in half of the cell lines and increasing miR-27a and miR-642 generally increased cisplatin sensitivity. 9059 hsa-mir-27a Urinary Bladder Neoplasms 22954303 Decreasing miR-138 increased the cisplatin sensitivity in half of the cell lines and increasing miR-27a and miR-642 generally increased cisplatin sensitivity. 9060 hsa-mir-642a Urinary Bladder Neoplasms 22954303 Decreasing miR-138 increased the cisplatin sensitivity in half of the cell lines and increasing miR-27a and miR-642 generally increased cisplatin sensitivity. 9061 hsa-mir-642b Urinary Bladder Neoplasms 22954303 Decreasing miR-138 increased the cisplatin sensitivity in half of the cell lines and increasing miR-27a and miR-642 generally increased cisplatin sensitivity. 9062 hsa-mir-944 Urinary Bladder Neoplasms 22954303 Three miRNAs were associated with both response (to chemotherapy) and survival (886-3p, 923, 944). 9063 hsa-mir-200c Stomach Neoplasms 22954417 The miR-200c blood expression levels in GC patients were significantly higher than in normal controls (p = 0.018). increased miR-200c levels are detected in the blood of gastric cancer patients. MiR-200c has the potential to be a predictor of progression and survival. 9064 hsa-mir-151a Stomach Neoplasms 22956063 Plasma miRNA-199a-3p and miRNA-151-5p were significantly elevated (p < 0.05) and were significantly reduced after surgery (p < 0.05) in gastric cancer patients. 9065 hsa-mir-151b Stomach Neoplasms 22956063 Plasma miRNA-199a-3p and miRNA-151-5p were significantly elevated (p < 0.05) and were significantly reduced after surgery (p < 0.05) in gastric cancer patients. 9066 hsa-mir-199a-1 Stomach Neoplasms 22956063 Plasma miRNA-199a-3p and miRNA-151-5p were significantly elevated (p < 0.05) and were significantly reduced after surgery (p < 0.05) in gastric cancer patients. 9067 hsa-mir-199a-2 Stomach Neoplasms 22956063 Plasma miRNA-199a-3p and miRNA-151-5p were significantly elevated (p < 0.05) and were significantly reduced after surgery (p < 0.05) in gastric cancer patients. 9068 hsa-mir-200a Melanoma 22956368 Loss of microRNA-200a and c, and microRNA-203 expression at the invasive front of primary cutaneous melanoma is associated with increased thickness and disease progression. 9069 hsa-mir-200c Melanoma 22956368 Loss of microRNA-200a and c, and microRNA-203 expression at the invasive front of primary cutaneous melanoma is associated with increased thickness and disease progression. 9070 hsa-mir-203 Melanoma 22956368 Loss of microRNA-200a and c, and microRNA-203 expression at the invasive front of primary cutaneous melanoma is associated with increased thickness and disease progression. 9071 hsa-mir-21 Carcinoma, Non-Small-Cell Lung 22956424 MicroRNA-21 (miR-21) expression promotes growth, metastasis, and chemo- or radioresistance in non-small cell lung cancer cells by targeting PTEN. 9072 hsa-mir-127 Osteosarcoma 22957032 Treatment with 4-phenylbutyrate increased acetylation of histones associated with 14q32 miRNAs, but interestingly, robust restoration of 14q32 miRNA expression, attenuation of cMYC expression, and induction of apoptosis required concomitant treatment with 5-Azacytidine, an inhibitor of DNA methylation. combination of these chromatin-modifying drugs may be a useful adjuvant in the treatment of rapidly progressive osteosarcoma. 9073 hsa-mir-411 Osteosarcoma 22957032 Treatment with 4-phenylbutyrate increased acetylation of histones associated with 14q32 miRNAs, but interestingly, robust restoration of 14q32 miRNA expression, attenuation of cMYC expression, and induction of apoptosis required concomitant treatment with 5-Azacytidine, an inhibitor of DNA methylation. combination of these chromatin-modifying drugs may be a useful adjuvant in the treatment of rapidly progressive osteosarcoma. 9074 hsa-mir-431 Osteosarcoma 22957032 Treatment with 4-phenylbutyrate increased acetylation of histones associated with 14q32 miRNAs, but interestingly, robust restoration of 14q32 miRNA expression, attenuation of cMYC expression, and induction of apoptosis required concomitant treatment with 5-Azacytidine, an inhibitor of DNA methylation. combination of these chromatin-modifying drugs may be a useful adjuvant in the treatment of rapidly progressive osteosarcoma. 9075 hsa-mir-432 Osteosarcoma 22957032 Treatment with 4-phenylbutyrate increased acetylation of histones associated with 14q32 miRNAs, but interestingly, robust restoration of 14q32 miRNA expression, attenuation of cMYC expression, and induction of apoptosis required concomitant treatment with 5-Azacytidine, an inhibitor of DNA methylation. combination of these chromatin-modifying drugs may be a useful adjuvant in the treatment of rapidly progressive osteosarcoma. 9076 hsa-mir-122 Hepatitis C 22957141 Silencing of microRNA-122 enhances interferon-alpha signaling in the liver through regulating SOCS3 promoter methylation. 9077 hsa-mir-219-2 Inflammation 22957142 Delayed resolution undermines endogenous resolution programs, altering miR-219-2 expression, increasing pro-inflammatory mediators and compromising SPM production that contribute to failed catabasis and homeostasis. 9078 hsa-mir-34a Lung Neoplasms 23036084 microRNA-34a Sensitizes Lung Cancer Cell Lines to DDP Treatment Independent of p53 Status. 9079 hsa-mir-155 Colonic Neoplasms 23036199 Adrenaline promotes cell proliferation and increases chemoresistance in colon cancer HT29 cells through induction of miR-155 9080 hsa-mir-200c Prostatic Neoplasms 23041061 Epithelial-to-mesenchymal transition leads to docetaxel resistance in prostate cancer and is mediated by reduced expression of miR-200c and miR-205 9081 hsa-mir-205 Prostatic Neoplasms 23041061 Epithelial-to-mesenchymal transition leads to docetaxel resistance in prostate cancer and is mediated by reduced expression of miR-200c and miR-205 9082 hsa-mir-155 Atherosclerosis 23041630 MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages 9083 hsa-mir-9-1 Colonic Neoplasms 23045246 Prospero homeobox 1 promotes epithelial-mesenchymal transition in colon cancer cells by inhibiting E-cadherin via miR-9 9084 hsa-mir-9-2 Colonic Neoplasms 23045246 Prospero homeobox 1 promotes epithelial-mesenchymal transition in colon cancer cells by inhibiting E-cadherin via miR-9 9085 hsa-mir-141 Ovarian Neoplasms 23045278 miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells 9086 hsa-mir-145 Breast Neoplasms 23049906 MiR-145 regulates epithelial to mesenchymal transition of breast cancer cells by targeting Oct4 9087 hsa-mir-196b Glioma 23049982 We have provided the first evidence that expression of miR-196b was associated with the occurrence of pre-operative seizures in low-grade gliomas,and may predict seizure prognosis in patients without pre-operative seizures 9088 hsa-mir-155 Carcinoma, Renal Cell 23050614 MicroRNA-155 is a predictive marker for survival in patients with clear cell renal cell carcinoma 9089 hsa-mir-21 Breast Neoplasms 23052036 Endocrine Disruptors Fludioxonil and Fenhexamid Stimulate miR-21 Expression in Breast Cancer Cells 9090 hsa-mir-21 Breast Neoplasms 23052693 Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer 9091 hsa-mir-92a-1 Breast Neoplasms 23052693 Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer 9092 hsa-mir-92a-2 Breast Neoplasms 23052693 Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer 9093 hsa-mir-451a Esophageal Neoplasms 23053883 Effect of miR-451 on the Biological Behavior of the Esophageal Carcinoma Cell Line EC9706 9094 hsa-mir-498 Neoplasms 23055531 1,25-Dihydroxyvitamin D3 suppresses telomerase expression and human cancer growth through microRNA-498 9095 hsa-mir-122 Hepatitis B 23055569 Inhibition of Alpha Interferon (IFN-alpha)-Induced MicroRNA-122 Negatively Affects the Anti-Hepatitis B Virus Efficiency of IFN-α 9096 hsa-mir-100 Leukemia, Myeloid, Acute 23055746 Upregulation of microRNA-100 predicts poor prognosis in patients with pediatric acute myeloid leukemia 9097 hsa-mir-17 Nasopharyngeal Neoplasms 23056289 Circulating miR-17, miR-20a, miR-29c, and miR-223 combined as non-invasive biomarkers in nasopharyngeal carcinoma 9098 hsa-mir-20a Nasopharyngeal Neoplasms 23056289 Circulating miR-17, miR-20a, miR-29c, and miR-223 combined as non-invasive biomarkers in nasopharyngeal carcinoma 9099 hsa-mir-223 Nasopharyngeal Neoplasms 23056289 Circulating miR-17, miR-20a, miR-29c, and miR-223 combined as non-invasive biomarkers in nasopharyngeal carcinoma 9100 hsa-mir-29c Nasopharyngeal Neoplasms 23056289 Circulating miR-17, miR-20a, miR-29c, and miR-223 combined as non-invasive biomarkers in nasopharyngeal carcinoma 9101 hsa-mir-148a Colorectal Neoplasms 23056401 The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer 9102 hsa-mir-1280 Urinary Bladder Neoplasms 23056431 MicroRNA-1280 inhibits invasion and metastasis by targeting ROCK1 in bladder cancer 9103 hsa-mir-205 Uterine Cervical Neoplasms 23056551 miR-205 expression promotes cell proliferation and migration of human cervical cancer cells 9104 hsa-mir-122 Breast Neoplasms 23056576 MiR-122 inhibits cell proliferation and tumorigenesis of breast cancer by targeting IGF1R 9105 hsa-mir-371a Testicular Neoplasms 23059743 MicroRNAs miR-371-3 in serum as diagnostic tools in the management of testicular germ cell tumours 9106 hsa-mir-17 Leukemia, Myeloid 23059786 HIF-1a downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation 9107 hsa-mir-20a Leukemia, Myeloid 23059786 HIF-1a downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation 9108 hsa-mir-153-1 Prostatic Neoplasms 23060044 Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer 9109 hsa-mir-153-2 Prostatic Neoplasms 23060044 Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer 9110 hsa-mir-187 Breast Neoplasms 23060431 miR-187 Is an Independent Prognostic Factor in Breast Cancer and Confers Increased Invasive Potential In Vitro 9111 hsa-mir-199a-1 Neoplasms 23060436 The microRNA miR-199a-5p down-regulation switches on wound angiogenesis by derepressing the v-ets erythroblastosis virus E26 oncogene homolog 1-matrix metalloproteinase-1 pathway 9112 hsa-mir-199a-2 Neoplasms 23060436 The microRNA miR-199a-5p down-regulation switches on wound angiogenesis by derepressing the v-ets erythroblastosis virus E26 oncogene homolog 1-matrix metalloproteinase-1 pathway 9113 hsa-mir-218-1 Neoplasms 23060446 miR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells 9114 hsa-mir-218-2 Neoplasms 23060446 miR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells 9115 hsa-mir-371a Thyroid Neoplasms 23062364 Activation of the two microRNA clusters C19MC and miR-371-3 does not play prominent role in thyroid cancer 9116 hsa-mir-210 Carcinoma, Renal Cell 23064048 Serum miR-210 as a novel biomarker for molecular diagnosis of clear cell renal cell carcinoma 9117 hsa-mir-337 Leukemia, Myeloid, Acute 23065518 A polymorphism in the 3'-untranslated region of the NPM1 gene causes illegitimate regulation by microRNA-337-5p and correlates with adverse outcome in acute myeloid leukemia 9118 hsa-mir-200c Stomach Neoplasms 23065816 G-A variant in miR-200c binding site of EFNA1 alters susceptibility to gastric cancer 9119 hsa-mir-214 Carcinoma, Hepatocellular 23068095 MiR-214 inhibits cell growth in hepatocellular carcinoma through suppression of beta-catenin 9120 hsa-mir-198 Prostatic Neoplasms 23069480 Livin expression may be regulated by miR-198 in human prostate cancer cell lines 9121 hsa-mir-124-1 Prostatic Neoplasms 23069658 Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells 9122 hsa-mir-124-2 Prostatic Neoplasms 23069658 Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells 9123 hsa-mir-124-3 Prostatic Neoplasms 23069658 Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells 9124 hsa-mir-126 Kidney Diseases 23070235 Circulating levels of inflammation-associated miR-155 and endothelial-enriched miR-126 in patients with end-stage renal disease 9125 hsa-mir-155 Kidney Diseases 23070235 Circulating levels of inflammation-associated miR-155 and endothelial-enriched miR-126 in patients with end-stage renal disease 9126 hsa-mir-143 Pancreatic Neoplasms 23070684 miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway 9127 hsa-mir-1297 Lung Neoplasms 23071539 miR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2 9128 hsa-mir-511-1 Lung Neoplasms 23071539 miR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2 9129 hsa-mir-511-2 Lung Neoplasms 23071539 miR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2 9130 hsa-mir-101-1 Breast Neoplasms 23071542 MiR-101 is involved in human breast carcinogenesis by targeting Stathmin1 9131 hsa-mir-101-2 Breast Neoplasms 23071542 MiR-101 is involved in human breast carcinogenesis by targeting Stathmin1 9132 hsa-mir-155 Breast Neoplasms 23071695 Serum microRNA-155 as a potential biomarker to track disease in breast cancer 9133 hsa-mir-203 Lung Neoplasms 23073851 miR-203 negatively regulates survivin protein expression and inhibits the proliferation and invasion of lung cancer cells 9134 hsa-mir-200a Carcinoma, Renal Cell 23074016 The entire miR-200 seed family is strongly deregulated in clear cell renal cell cancer compared to the proximal tubular epithelial cells of the kidney 9135 hsa-mir-200b Carcinoma, Renal Cell 23074016 The entire miR-200 seed family is strongly deregulated in clear cell renal cell cancer compared to the proximal tubular epithelial cells of the kidney 9136 hsa-mir-200c Carcinoma, Renal Cell 23074016 The entire miR-200 seed family is strongly deregulated in clear cell renal cell cancer compared to the proximal tubular epithelial cells of the kidney 9137 hsa-mir-200c Ovarian Neoplasms 23074172 Restoration of miR-200c to Ovarian Cancer Reduces Tumor Burden and Increases Sensitivity to Paclitaxel 9138 hsa-mir-23b Prostatic Neoplasms 23074286 miR-23b Represses Proto-oncogene Src Kinase and Functions as Methylation-Silenced Tumor Suppressor with Diagnostic and Prognostic Significance in Prostate Cancer 9139 hsa-mir-145 Glioma 23076445 MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells 9140 hsa-mir-328 Glioblastoma 23077581 MiR-328 expression is decreased in high-grade gliomas and is associated with worse survival in primary glioblastoma 9141 hsa-mir-21 Glioma 23077620 Silencing of microRNA-21 confers radio-sensitivity through inhibition of the PI3K/AKT pathway and enhancing autophagy in malignant glioma cell lines 9142 hsa-mir-370 Leukemia, Myeloid, Acute 23077663 Integration of SNP and mRNA arrays with microRNA profiling reveals that MiR-370 is upregulated and targets NF1 in acute myeloid leukemia 9143 hsa-mir-29a Lymphoma, B-Cell 23079660 Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas 9144 hsa-mir-29b-1 Lymphoma, B-Cell 23079660 Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas 9145 hsa-mir-29b-2 Lymphoma, B-Cell 23079660 Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-Cell lymphomas 9146 hsa-mir-150 Leukemia 23079661 Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia 9147 hsa-mir-125a Carcinoma, Hepatocellular 23079745 SIRT7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors mir-125a-5p and mir-125b 9148 hsa-mir-125b-1 Carcinoma, Hepatocellular 23079745 SIRT7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors mir-125a-5p and mir-125b 9149 hsa-mir-125b-2 Carcinoma, Hepatocellular 23079745 SIRT7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors mir-125a-5p and mir-125b 9150 hsa-mir-21 Neuroblastoma 23084187 Micro-RNA-21 regulates the sensitivity to cisplatin in human neuroblastoma cells 9151 hsa-mir-34a Breast Neoplasms 23085450 MicroRNA-34a modulates chemosensitivity of breast cancer cells to adriamycin by targeting Notch1 9152 hsa-mir-122 Hepatitis C 23085648 Hepatic and serum levels of miR-122 after chronic HCV-induced fibrosis 9153 hsa-mir-181a-1 Neoplasms 23085757 miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer 9154 hsa-mir-181a-2 Neoplasms 23085757 miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer 9155 hsa-mir-199a-1 Neoplasms 23085757 miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer 9156 hsa-mir-199a-2 Neoplasms 23085757 miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer 9157 hsa-mir-30d Neoplasms 23085757 miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer 9158 hsa-mir-106b Carcinoma, Hepatocellular 23087084 miR-106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma 9159 hsa-mir-376a-1 Glioblastoma 23093778 Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells 9160 hsa-mir-376a-2 Glioblastoma 23093778 Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells 9161 hsa-mir-17 Prostatic Neoplasms 23095762 miR-17-5p targets the p300/CBP-associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells 9162 hsa-mir-26a-1 Leukemia, Myeloid, Acute 23096114 The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells 9163 hsa-mir-26a-2 Leukemia, Myeloid, Acute 23096114 The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells 9164 hsa-mir-18a Nasopharyngeal Neoplasms 23097559 miR-18a promotes malignant progression by impairing microRNA biogenesis in nasopharyngeal carcinoma 9165 hsa-mir-181a-1 Leukemia, Myeloid, Acute 23100311 Lenalidomide-mediated enhanced translation of C/EBPalpha-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia 9166 hsa-mir-181a-2 Leukemia, Myeloid, Acute 23100311 Lenalidomide-mediated enhanced translation of C/EBPalpha-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia 9167 hsa-mir-29b-1 Multiple Myeloma 23100393 DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma 9168 hsa-mir-29b-2 Multiple Myeloma 23100393 DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma 9169 hsa-mir-375 Glioma 23103713 Correlation of microRNA-375 downregulation with unfavorable clinical outcome of patients with glioma 9170 hsa-mir-15a Multiple Myeloma 23104180 miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF 9171 hsa-mir-16-1 Multiple Myeloma 23104180 miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF 9172 hsa-mir-16-2 Multiple Myeloma 23104180 miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF 9173 hsa-mir-143 Urinary Bladder Neoplasms 23104321 Replacement treatment with microRNA-143 and -145 induces synergistic inhibition of the growth of human bladder cancer cells by regulating PI3K/Akt and MAPK signaling pathways 9174 hsa-mir-145 Urinary Bladder Neoplasms 23104321 Replacement treatment with microRNA-143 and -145 induces synergistic inhibition of the growth of human bladder cancer cells by regulating PI3K/Akt and MAPK signaling pathways 9175 hsa-mir-21 Glioma 23104517 MiR-21 expression in the tumor cell compartment holds unfavorable prognostic value in gliomas 9176 hsa-mir-21 Laryngeal Neoplasms 23104547 Downregulation of miR-21 regulates MMP-2 expression and suppress migration of Laryngeal squamous cell carcinoma 9177 hsa-mir-17 Carcinoma, Hepatocellular 23108086 High expression of serum miR-17-5p associated with poor prognosis in patients with hepatocellular carcinoma 9178 hsa-mir-145 Meningioma 23108408 miRNA-145 is downregulated in atypical and anaplastic meningiomas and negatively regulates motility and proliferation of meningioma cells 9179 hsa-mir-210 Neuroblastoma 23108914 MicroRNA-210 targets antiapoptotic Bcl-2 expression and mediates hypoxia-induced apoptosis of neuroblastoma cells 9180 hsa-mir-26a-1 Esophageal Neoplasms 23108995 MiR-26a regulates cell cycle and anoikis of human esophageal adenocarcinoma cells through Rb1-E2F1 signaling pathway 9181 hsa-mir-26a-2 Esophageal Neoplasms 23108995 MiR-26a regulates cell cycle and anoikis of human esophageal adenocarcinoma cells through Rb1-E2F1 signaling pathway 9182 hsa-mir-370 Cholangiocarcinoma 23110045 Silencing of miR-370 in human cholangiocarcinoma by allelic loss and interleukin-6 induced maternal to paternal epigenotype switch 9183 hsa-mir-429 Colorectal Neoplasms 23111103 MiR-429 is an independent prognostic factor in colorectal cancer and exerts its anti-apoptotic function by targeting SOX2 9184 hsa-mir-200a Breast Neoplasms 23112837 the expression and methylation status of miR-200f could be used as hypothetical biomarkers to assess the occurrence of EMT in breast cancer 9185 hsa-mir-200b Breast Neoplasms 23112837 the expression and methylation status of miR-200f could be used as hypothetical biomarkers to assess the occurrence of EMT in breast cancer 9186 hsa-mir-200c Breast Neoplasms 23112837 the expression and methylation status of miR-200f could be used as hypothetical biomarkers to assess the occurrence of EMT in breast cancer 9187 hsa-mir-29a Osteosarcoma 23113351 data obtained highlight the role of miRNA-29a in the regulation of osteoblastic cell apoptosis by silencing Bcl-2 and Mcl-1 and inducing E2F1 and E2F3 expression 9188 hsa-mir-29a Leukemia, Myeloid, Chronic-Phase 23113544 Regulation of Human RNase-L by the miR-29 Family Reveals a Novel Oncogenic Role in Chronic Myelogenous Leukemia 9189 hsa-mir-29b-1 Leukemia, Myeloid, Chronic-Phase 23113544 Regulation of Human RNase-L by the miR-29 Family Reveals a Novel Oncogenic Role in Chronic Myelogenous Leukemia 9190 hsa-mir-29b-2 Leukemia, Myeloid, Chronic-Phase 23113544 Regulation of Human RNase-L by the miR-29 Family Reveals a Novel Oncogenic Role in Chronic Myelogenous Leukemia 9191 hsa-mir-149 Colorectal Neoplasms 23115050 Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer 9192 hsa-mir-7-1 Head and Neck Neoplasms 23115635 Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7 9193 hsa-mir-7-2 Head and Neck Neoplasms 23115635 Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7 9194 hsa-mir-7-3 Head and Neck Neoplasms 23115635 Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7 9195 hsa-mir-27a Lung Neoplasms 23117485 miR-27a regulates the self renewal of the H446 small cell lung cancer cell line in vitro 9196 hsa-mir-27a Carcinoma, Renal Cell 23118855 A genetic variant in pre-miR-27a is associated with a reduced renal cell cancer risk in a Chinese population 9197 hsa-mir-137 Mouth Neoplasms 23121285 MicroRNA-137 promoter methylation in oral lichen planus and oral squamous cell carcinoma 9198 hsa-mir-125b-1 Myocardial Ischemia 23123599 SR-A deficiency reduces myocardial ischemia/reperfusion injury; involvement of increased microRNA-125b expression in macrophages 9199 hsa-mir-125b-2 Myocardial Ischemia 23123599 SR-A deficiency reduces myocardial ischemia/reperfusion injury; involvement of increased microRNA-125b expression in macrophages 9200 hsa-mir-101-1 Hepatitis B 23124077 miR-101 is down-regulated by the hepatitis B virus x protein and induces aberrant DNA methylation by targeting DNA methyltransferase 3A 9201 hsa-mir-101-2 Hepatitis B 23124077 miR-101 is down-regulated by the hepatitis B virus x protein and induces aberrant DNA methylation by targeting DNA methyltransferase 3A 9202 hsa-mir-10b Breast Neoplasms 23125021 miR-10b*, a master inhibitor of the cell cycle, is down-regulated in human breast tumours 9203 hsa-mir-144 Nasopharyngeal Neoplasms 23125220 MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN 9204 hsa-mir-205 Parkinson Disease 23125283 MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein 9205 hsa-mir-122 Hepatitis C 23126531 Alcohol Facilitates HCV RNA Replication Via Up-Regulation of miR-122 Expression and Inhibition of Cyclin G1 in Human Hepatoma Cells 9206 hsa-mir-143 Colorectal Neoplasms 23128394 Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression 9207 hsa-mir-145 Colorectal Neoplasms 23128394 Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression 9208 hsa-mir-125b-1 Stomach Neoplasms 23128435 MicroRNA-125b expression in gastric adenocarcinoma and its effect on the proliferation of gastric cancer cells 9209 hsa-mir-125b-2 Stomach Neoplasms 23128435 MicroRNA-125b expression in gastric adenocarcinoma and its effect on the proliferation of gastric cancer cells 9210 hsa-mir-17 Lupus Erythematosus, Systemic 23129428 Dual downregulation of microRNA 17-5p and E2F1 transcriptional factor in pediatric systemic lupus erythematosus patients 9211 hsa-mir-9-1 HIV 23129528 The microRNA-9/B-lymphocyte-induced maturation protein-1/IL-2 axis is differentially regulated in progressive HIV infection 9212 hsa-mir-9-2 HIV 23129528 The microRNA-9/B-lymphocyte-induced maturation protein-1/IL-2 axis is differentially regulated in progressive HIV infection 9213 hsa-mir-495 Leukemia 23132946 MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia 9214 hsa-mir-574 Lung Neoplasms 23133627 MicroRNA-574-5p was pivotal for TLR9 signaling enhanced tumor progression via down-regulating checkpoint suppressor 1 in human lung cancer 9215 hsa-mir-7-1 Lung Neoplasms 23135998 MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway 9216 hsa-mir-7-2 Lung Neoplasms 23135998 MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway 9217 hsa-mir-7-3 Lung Neoplasms 23135998 MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway 9218 hsa-mir-126 Heart Failure 23136161 Loss of AngiomiR-126 and 130a in Angiogenic Early Outgrowth Cells From Patients With Chronic Heart Failure: Role for Impaired In Vivo Neovascularization and Cardiac Repair Capacity 9219 hsa-mir-130a Heart Failure 23136161 Loss of AngiomiR-126 and 130a in Angiogenic Early Outgrowth Cells From Patients With Chronic Heart Failure: Role for Impaired In Vivo Neovascularization and Cardiac Repair Capacity 9220 hsa-mir-224 Prostatic Neoplasms 23136246 Downregulation and Prognostic Performance of MicroRNA 224 Expression in Prostate Cancer 9221 hsa-mir-133a-1 Myocardial Infarction 23137501 Relation of circulating MicroRNA-133a concentrations with myocardial damage and clinical prognosis in ST-elevation myocardial infarction 9222 hsa-mir-133a-2 Myocardial Infarction 23137501 Relation of circulating MicroRNA-133a concentrations with myocardial damage and clinical prognosis in ST-elevation myocardial infarction 9223 hsa-mir-186 Colorectal Neoplasms 23137536 miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells 9224 hsa-mir-216b Colorectal Neoplasms 23137536 miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells 9225 hsa-mir-337 Colorectal Neoplasms 23137536 miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells 9226 hsa-mir-760 Colorectal Neoplasms 23137536 miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells 9227 hsa-mir-196a-1 Mouth Neoplasms 23138850 miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells 9228 hsa-mir-196a-2 Mouth Neoplasms 23138850 miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells 9229 hsa-mir-197 Pancreatic Neoplasms 23139153 MiR-197 induces epithelial-mesenchymal transition in pancreatic cancer cells by targeting p120 catenin 9230 hsa-mir-101-1 Pancreatic Neoplasms 23139258 The good, the bad and the ugly: a tale of miR-101, miR-21 and miR-155 in pancreatic intraductal papillary mucinous neoplasms 9231 hsa-mir-101-2 Pancreatic Neoplasms 23139258 The good, the bad and the ugly: a tale of miR-101, miR-21 and miR-155 in pancreatic intraductal papillary mucinous neoplasms 9232 hsa-mir-155 Pancreatic Neoplasms 23139258 The good, the bad and the ugly: a tale of miR-101, miR-21 and miR-155 in pancreatic intraductal papillary mucinous neoplasms 9233 hsa-mir-21 Pancreatic Neoplasms 23139258 The good, the bad and the ugly: a tale of miR-101, miR-21 and miR-155 in pancreatic intraductal papillary mucinous neoplasms 9234 hsa-mir-101-1 Lupus Erythematosus, Systemic 23139385 MicroRNA-101, mitogen-activated protein kinases and mitogen-activated protein kinases phosphatase-1 in systemic lupus erythematosus 9235 hsa-mir-101-2 Lupus Erythematosus, Systemic 23139385 MicroRNA-101, mitogen-activated protein kinases and mitogen-activated protein kinases phosphatase-1 in systemic lupus erythematosus 9236 hsa-mir-34a Pancreatic Neoplasms 23140286 Genistein Inhibits Cell Growth and Induces Apoptosis Through Up-regulation of miR-34a in Pancreatic Cancer Cell 9237 hsa-mir-1-1 Lung Neoplasms 23142026 MicroRNA-1 targets Slug and endows lung cancer A549 cells with epithelial and anti-tumorigenic properties 9238 hsa-mir-1-2 Lung Neoplasms 23142026 MicroRNA-1 targets Slug and endows lung cancer A549 cells with epithelial and anti-tumorigenic properties 9239 hsa-mir-29b-1 Lupus Erythematosus, Systemic 23142053 MicroRNA-29b contributes to DNA hypomethylation of CD4+ T cells in systemic lupus erythematosus by indirectly targeting DNA methyltransferase 1 9240 hsa-mir-29b-2 Lupus Erythematosus, Systemic 23142053 MicroRNA-29b contributes to DNA hypomethylation of CD4+ T cells in systemic lupus erythematosus by indirectly targeting DNA methyltransferase 1 9241 hsa-mir-152 Glioma 23142217 MiR-15b and miR-152 reduce glioma cell invasion and angiogenesis via NRP-2 and MMP-3 9242 hsa-mir-15b Glioma 23142217 MiR-15b and miR-152 reduce glioma cell invasion and angiogenesis via NRP-2 and MMP-3 9243 hsa-mir-24-1 Glioma 23142218 MiR-24 regulates the proliferation and invasion of glioma by ST7L via beta-catenin/Tcf-4 signaling 9244 hsa-mir-24-2 Glioma 23142218 MiR-24 regulates the proliferation and invasion of glioma by ST7L via beta-catenin/Tcf-4 signaling 9245 hsa-mir-517a Carcinoma, Hepatocellular 23142219 Down-regulation of miR-517a and miR-517c promotes proliferation of hepatocellular carcinoma cells via targeting Pyk2 9246 hsa-mir-517c Carcinoma, Hepatocellular 23142219 Down-regulation of miR-517a and miR-517c promotes proliferation of hepatocellular carcinoma cells via targeting Pyk2 9247 hsa-mir-29c Nasopharyngeal Neoplasms 23142283 MicroRNA-29c enhances the sensitivities of human nasopharyngeal carcinoma to cisplatin-based chemotherapy and radiotherapy 9248 hsa-mir-1290 Colonic Neoplasms 23142292 Up-regulation of microRNA-1290 impairs cytokinesis and affects the reprogramming of colon cancer cells 9249 hsa-mir-326 Lung Neoplasms 23142363 miR-326 associates with biochemical markers of bone turnover in lung cancer bone metastasis 9250 hsa-mir-27a Cardiomyopathies 23143062 MicroRNA-27a regulates cardiomyocytic apoptosis during cardioplegia-induced cardiac arrest by targeting interleukin 10-related pathways 9251 hsa-mir-135b Colorectal Neoplasms 23143558 Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-beta in colorectal cells 9252 hsa-mir-196a-1 Lung Neoplasms 23143626 Hsa-miR-196a2 functional SNP is associated with severe toxicity after platinum-based chemotherapy of advanced nonsmall cell lung cancer patients in a Chinese population 9253 hsa-mir-196a-2 Lung Neoplasms 23143626 Hsa-miR-196a2 functional SNP is associated with severe toxicity after platinum-based chemotherapy of advanced nonsmall cell lung cancer patients in a Chinese population 9254 hsa-mir-126 Diabetes Mellitus, Type 2 23144172 AngiomiR-126 expression and secretion from circulating CD34+ and CD14+ PBMCs:role for proangiogenic effects and alterations in type 2 diabetics 9255 hsa-mir-149 Stomach Neoplasms 23144691 MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer 9256 hsa-mir-550a-1 Carcinoma, Hepatocellular 23145039 MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic polyadenylation element-binding protein 4 in hepatocellular carcinoma 9257 hsa-mir-550a-2 Carcinoma, Hepatocellular 23145039 MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic polyadenylation element-binding protein 4 in hepatocellular carcinoma 9258 hsa-mir-550a-3 Carcinoma, Hepatocellular 23145039 MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic polyadenylation element-binding protein 4 in hepatocellular carcinoma 9259 hsa-mir-34b Prostatic Neoplasms 23147995 miRNA-34b Inhibits Prostate Cancer through Demethylation, Active Chromatin Modifications, and AKT Pathways 9260 hsa-mir-210 Carcinoma, Renal Cell 23150176 MiR-210 expression in tumor tissue and in vitro effects of its silencing in renal cell carcinoma 9261 hsa-mir-100 Lung Neoplasms 23151088 MicroRNA-100 is a potential molecular marker of non-small cell lung cancer and functions as a tumor suppressor by targeting polo-like kinase 1 9262 hsa-mir-96 Carcinoma, Hepatocellular 23151657 Inhibition of miR-96 expression reduces cell proliferation and clonogenicity of HepG2 hepatoma cells 9263 hsa-mir-137 Melanoma 23151846 miR-137 Inhibits the Invasion of Melanoma Cells through Downregulation of Multiple Oncogenic Target Genes 9264 hsa-mir-204 Stomach Neoplasms 23152059 miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer 9265 hsa-mir-182 HIV-1 23153509 Down-regulation of NAMPT expression by miR-182 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation 9266 hsa-mir-720 Esophageal Neoplasms 23154181 SnoN/SKIL modulates proliferation through control of hsa-miR-720 transcription in esophageal cancer cells 9267 hsa-mir-638 Neoplasms 23155245 Expression of human endogenous retrovirus-K coincides with that of micro-RNA-663 and -638 in germ-cell tumor cells 9268 hsa-mir-663a Neoplasms 23155245 Expression of human endogenous retrovirus-K coincides with that of micro-RNA-663 and -638 in germ-cell tumor cells 9269 hsa-mir-663b Neoplasms 23155245 Expression of human endogenous retrovirus-K coincides with that of micro-RNA-663 and -638 in germ-cell tumor cells 9270 hsa-mir-34b Mesothelioma 23155254 MicroRNA miR-34b/c enhances cellular radiosensitivity of malignant pleural mesothelioma cells 9271 hsa-mir-34c Mesothelioma 23155254 MicroRNA miR-34b/c enhances cellular radiosensitivity of malignant pleural mesothelioma cells 9272 hsa-mir-211 Pancreatic Neoplasms 23155457 High-throughput microRNA (miRNAs) arrays unravel the prognostic role of MiR-211 in pancreatic cancer 9273 hsa-mir-1-1 Cardiomegaly 23156720 Effects of microRNA-1 on negatively regulating L-type calcium channel beta2 subunit gene expression during cardiac hypertrophy 9274 hsa-mir-1-2 Cardiomegaly 23156720 Effects of microRNA-1 on negatively regulating L-type calcium channel beta2 subunit gene expression during cardiac hypertrophy 9275 hsa-mir-383 Medulloblastoma 23157748 Compared with normal brain tissue, decreased expression of miR-383 but elevated expression of PRDX3 are medulloblastoma tumour and Daoy cell lines 9276 hsa-mir-200c Urinary Bladder Neoplasms 23159064 Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2,9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells 9277 hsa-mir-30c-1 Lung Neoplasms 23159078 Single nucleotide polymorphism in flanking region of miR-30c influences the maturing process of miR-30c in lung carcinoma 9278 hsa-mir-30c-2 Lung Neoplasms 23159078 Single nucleotide polymorphism in flanking region of miR-30c influences the maturing process of miR-30c in lung carcinoma 9279 hsa-mir-21 Wounds and Injuries 23159215 miR-21 regulates skin wound healing by targeting multiple aspects of the healing process 9280 hsa-mir-218-1 Neoplasms, Squamous Cell 23159910 Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma 9281 hsa-mir-218-2 Neoplasms, Squamous Cell 23159910 Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma 9282 hsa-mir-150 Scleroderma, Systemic 23159943 miR-150 Down-Regulation Contributes to the Constitutive Type I Collagen Overexpression in Scleroderma Dermal Fibroblasts via the Induction of Integrin β3 9283 hsa-mir-125b-1 Uterine Cervical Neoplasms 23160634 MiR-125b Inhibits Tumor Growth and Promotes Apoptosis of Cervical Cancer Cells by Targeting Phosphoinositide 3-Kinase Catalytic Subunit Delta 9284 hsa-mir-125b-2 Uterine Cervical Neoplasms 23160634 MiR-125b Inhibits Tumor Growth and Promotes Apoptosis of Cervical Cancer Cells by Targeting Phosphoinositide 3-Kinase Catalytic Subunit Delta 9285 hsa-mir-199a-1 Melanoma 23162627 Let-7b and microRNA-199a inhibit the proliferation of B16F10 melanoma cells 9286 hsa-mir-199a-2 Melanoma 23162627 Let-7b and microRNA-199a inhibit the proliferation of B16F10 melanoma cells 9287 hsa-mir-155 Breast Neoplasms 23162645 miR-155 and miR-31 are differentially expressed in breast cancer patients and are correlated with the estrogen receptor and progesterone receptor status 9288 hsa-mir-31 Breast Neoplasms 23162645 miR-155 and miR-31 are differentially expressed in breast cancer patients and are correlated with the estrogen receptor and progesterone receptor status 9289 hsa-mir-195 Osteosarcoma 23162665 microRNA-195 suppresses osteosarcoma cell invasion and migration in vitro by targeting FASN 9290 hsa-mir-133a-1 Cardiomegaly 23166348 Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy 9291 hsa-mir-133a-2 Cardiomegaly 23166348 Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy 9292 hsa-mir-361 Neoplasms, Squamous Cell 23166713 The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinoma 9293 hsa-mir-99a Carcinoma, Renal Cell 23173671 MicroRNA-99a induces G1-phase cell cycle arrest and suppresses tumorigenicity in renal cell carcinoma 9294 hsa-mir-99b Carcinoma, Renal Cell 23173671 MicroRNA-99a induces G1-phase cell cycle arrest and suppresses tumorigenicity in renal cell carcinoma 9295 hsa-mir-210 Neoplasms 23173806 Considering that the exact function of miR-210 is still not well characterized and understood, more investigations should be performed to promote the success of therapeutic-clinical use of miR-210 in cancer 9296 hsa-mir-100 Urinary Bladder Neoplasms 23173870 Reduced expression of microRNA-100 confers unfavorable prognosis in patients with bladder cancer 9297 hsa-mir-199a-1 Carcinoma, Renal Cell 23174576 A decreased expression of miR-199a is significantly correlated with a higher tumor stage, a greater likeliness of tumor recurrence, and a poorer prognosis in RCC patients 9298 hsa-mir-199a-2 Carcinoma, Renal Cell 23174576 A decreased expression of miR-199a is significantly correlated with a higher tumor stage, a greater likeliness of tumor recurrence, and a poorer prognosis in RCC patients 9299 hsa-mir-216a Pancreatic Neoplasms 23174591 The down-regulated expression of miR-216a in pancreatic cancer suggests the involvement of miR-216a in the tumorigenesis and development of pancreatic cancer 9300 hsa-mir-21 Colorectal Neoplasms 23174819 MiR-21 regulates biological behavior through the PTEN/PI-3 K/Akt signaling pathway in human colorectal cancer cells 9301 hsa-mir-29c Neoplasms 23175151 MicroRNA profiling of peripheral nerve sheath tumours identifies miR-29c as a tumour suppressor gene involved in tumour progression 9302 hsa-mir-27a Stomach Neoplasms 23175237 MicroRNA-27a inhibitors alone or in combination with perifosine suppress the growth of gastric cancer cells 9303 hsa-mir-16-1 Glioma 23175429 Zyxin may be one of putative target genes of miR-16-1 9304 hsa-mir-16-2 Glioma 23175429 Zyxin may be one of putative target genes of miR-16-1 9305 hsa-mir-657 Carcinoma, Hepatocellular 23175432 MiR-657 promotes tumorigenesis in hepatocellular carcinoma by targeting transducin-like enhancer protein 1 through NF-kB pathways 9306 hsa-mir-15a Neuroblastoma 23176145 MicroRNA-15a promotes neuroblastoma migration by targeting reversion-inducing cysteine-rich protein with Kazal motifs (RECK) and regulating matrix metalloproteinase-9 expression 9307 hsa-mir-135a-1 Carcinoma, Renal Cell 23176581 Tumor-suppressive microRNA-135a inhibits cancer cell proliferation by targeting the c-MYC oncogene in renal cell carcinoma 9308 hsa-mir-135a-2 Carcinoma, Renal Cell 23176581 Tumor-suppressive microRNA-135a inhibits cancer cell proliferation by targeting the c-MYC oncogene in renal cell carcinoma 9309 hsa-mir-21 Pancreatic Neoplasms 23177026 The serum miR-21 level serves as a predictor for the chemosensitivity of advanced pancreatic cancer, and miR-21 expression confers chemoresistance by targeting FasL 9310 hsa-mir-137 Lung Neoplasms 23178712 miR-137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6 9311 hsa-mir-101-1 Neoplasms 23178713 MicroRNA-101 suppresses SOX9-dependent tumorigenicity and promotes favorable prognosis of human hepatocellular carcinoma 9312 hsa-mir-101-2 Neoplasms 23178713 MicroRNA-101 suppresses SOX9-dependent tumorigenicity and promotes favorable prognosis of human hepatocellular carcinoma 9313 hsa-mir-29b-1 Leukemia, Myeloid, Acute 23178755 Increased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: a novel epigenetic-targeting approach in acute myeloid leukemia 9314 hsa-mir-29b-2 Leukemia, Myeloid, Acute 23178755 Increased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: a novel epigenetic-targeting approach in acute myeloid leukemia 9315 hsa-mir-106a Colorectal Neoplasms 23178825 miR-106a overexpression and pRB downregulation in sporadic colorectal cancer 9316 hsa-mir-137 Neoplasms 23178914 miR-137 restoration sensitizes multidrug-resistant MCF-7/ADM cells to anticancer agents by targeting YB-1 9317 hsa-mir-29b-1 Ovarian Neoplasms 23179556 Anticancer role of MUC1 aptamer-miR-29b chimera in epithelial ovarian carcinoma cells through regulation of PTEN methylation 9318 hsa-mir-29b-2 Ovarian Neoplasms 23179556 Anticancer role of MUC1 aptamer-miR-29b chimera in epithelial ovarian carcinoma cells through regulation of PTEN methylation 9319 hsa-mir-1290 Breast Neoplasms 23183268 MiR-1290 and its potential targets are associated with characteristics of estrogen receptor alpha-positive breast cancer 9320 hsa-mir-133a-1 Liver Cirrhosis 23183523 miR-133a mediates TGF-beta-dependent de-repression of collagen-synthesis in hepatic stellate cells during liver fibrosis 9321 hsa-mir-133a-2 Liver Cirrhosis 23183523 miR-133a mediates TGF-beta-dependent de-repression of collagen-synthesis in hepatic stellate cells during liver fibrosis 9322 hsa-mir-211 Glioma 23183822 Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis,Chemosensitivity and Radiosensitivity 9323 hsa-mir-302a Breast Neoplasms 23184229 MicroRNA-302 Replacement Therapy Sensitizes Breast Cancer Cells to Ionizing Radiation 9324 hsa-mir-182 Prostatic Neoplasms 23184537 Expression of MicroRNAs associated with Gleason grading system in prostate cancer: miR-182-5p is a useful marker for high grade prostate cancer 9325 hsa-mir-367 Uterine Cervical Neoplasms 23185040 The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1 9326 hsa-mir-302a Uterine Cervical Neoplasms 23185040 The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1 9327 hsa-mir-9-1 Glioma 23185366 The CREB-miR-9 negative feedback minicircuitry coordinates the migration and proliferation of glioma cells 9328 hsa-mir-9-2 Glioma 23185366 The CREB-miR-9 negative feedback minicircuitry coordinates the migration and proliferation of glioma cells 9329 hsa-mir-200c Breast Neoplasms 23185507 miR-200c targets a NF-kB up-regulated TrkB/NTF3 autocrine signaling loop to enhance anoikis sensitivity in triple negative breast cancer 9330 hsa-mir-214 Glioma 23187003 microRNA-214-mediated UBC9 expression in glioma 9331 hsa-mir-22 Esophageal Neoplasms 23188185 Increased miRNA-22 expression sensitizes esophageal squamous cell carcinoma to irradiation 9332 hsa-mir-153-1 Neoplasms, Glandular and Epithelial 23188671 Downregulation of miR-153 contributes to epithelial-mesenchymal transition and tumor metastasis in human epithelial cancer 9333 hsa-mir-153-2 Neoplasms, Glandular and Epithelial 23188671 Downregulation of miR-153 contributes to epithelial-mesenchymal transition and tumor metastasis in human epithelial cancer 9334 hsa-mir-320a Prostatic Neoplasms 23188675 MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway 9335 hsa-mir-98 Prostatic Neoplasms 23188821 Identification of microRNA-98 as a Therapeutic Target Inhibiting Prostate Cancer Growth and a Biomarker Induced by Vitamin D 9336 hsa-mir-23b Carcinoma, Renal Cell 23189187 Inhibition of PTEN gene expression by oncogenic miR-23b-3p in renal cancer 9337 hsa-mir-29b-1 Multiple Myeloma 23190608 miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1 9338 hsa-mir-29b-2 Multiple Myeloma 23190608 miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1 9339 hsa-mir-26a-1 Melanoma 23190898 MicroRNA-26a Is Strongly Downregulated in Melanoma and Induces Cell Death through Repression of Silencer of Death Domains 9340 hsa-mir-26a-2 Melanoma 23190898 MicroRNA-26a Is Strongly Downregulated in Melanoma and Induces Cell Death through Repression of Silencer of Death Domains 9341 hsa-mir-7-1 Neuroblastoma 23192662 Overexpression of miR-7-1 Increases Efficacy of Green Tea Polyphenols for Induction of Apoptosis in Human Malignant Neuroblastoma SH-SY5Y and SK-N-DZ Cells 9342 hsa-mir-7-2 Neuroblastoma 23192662 Overexpression of miR-7-1 Increases Efficacy of Green Tea Polyphenols for Induction of Apoptosis in Human Malignant Neuroblastoma SH-SY5Y and SK-N-DZ Cells 9343 hsa-mir-133b Gastrointestinal Neoplasms 23196799 Fascin-1 overexpression and miR-133b downregulation in the progression of gastrointestinal stromal tumor 9344 hsa-mir-320a Myasthenia Gravis 23196978 MiR-320a is Downregulated in Patients with Myasthenia Gravis and Modulates Inflammatory Cytokines Production by Targeting Mitogen-activated Protein Kinase 1 9345 hsa-mir-145 Lupus Erythematosus, Systemic 23199328 Decreased microRNA(miR)-145 and increased miR-224 expression in T cells from patients with systemic lupus erythematosus involved in lupus immunopathogenesis 9346 hsa-mir-224 Lupus Erythematosus, Systemic 23199328 Decreased microRNA(miR)-145 and increased miR-224 expression in T cells from patients with systemic lupus erythematosus involved in lupus immunopathogenesis 9347 hsa-mir-421 Carcinoma, Squamous Cell 23199656 Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma 9348 hsa-mir-146a Neoplasms 23200854 Epistasis between MicroRNAs 155 and 146a during T Cell-Mediated Antitumor Immunity 9349 hsa-mir-155 Neoplasms 23200854 Epistasis between MicroRNAs 155 and 146a during T Cell-Mediated Antitumor Immunity 9350 hsa-mir-199a-1 Cystitis, Interstitial 23201090 miR-199a-5p Regulates Urothelial Permeability and May Play a Role in Bladder Pain Syndrome 9351 hsa-mir-199a-2 Cystitis, Interstitial 23201090 miR-199a-5p Regulates Urothelial Permeability and May Play a Role in Bladder Pain Syndrome 9352 hsa-mir-126 Myocytes, Cardiac 23201405 Synergistic induction of miR-126 by hypoxia and HDAC inhibitors in cardiac myocytes 9353 hsa-mir-21 Glioblastoma 23201752 MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma 9354 hsa-mir-146a Cerebral Infarction 23202363 Association of the miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms With Ischemic Stroke and Silent Brain Infarction Risk 9355 hsa-mir-149 Cerebral Infarction 23202363 Association of the miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms With Ischemic Stroke and Silent Brain Infarction Risk 9356 hsa-mir-196a-1 Cerebral Infarction 23202363 Association of the miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms With Ischemic Stroke and Silent Brain Infarction Risk 9357 hsa-mir-196a-2 Cerebral Infarction 23202363 Association of the miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms With Ischemic Stroke and Silent Brain Infarction Risk 9358 hsa-mir-17 Endometriosis 23203215 Plasma miR-17-5p, miR-20a and miR-22 are down-regulated in women with endometriosis 9359 hsa-mir-20a Endometriosis 23203215 Plasma miR-17-5p, miR-20a and miR-22 are down-regulated in women with endometriosis 9360 hsa-mir-22 Endometriosis 23203215 Plasma miR-17-5p, miR-20a and miR-22 are down-regulated in women with endometriosis 9361 hsa-mir-186 Lung Neoplasms 23204228 miR-186 Downregulation Correlates with Poor Survival in Lung Adenocarcinoma,Where It Interferes with Cell-Cycle Regulation 9362 hsa-mir-204 Glioma 23204229 Loss of miR-204 Expression Enhances Glioma Migration and Stem Cell-like Phenotype 9363 hsa-mir-544a Glioma 23205130 Downregulation of miR-544 in tissue, but not in serum, is a novel biomarker of malignant transformation in glioma 9364 hsa-mir-544b Glioma 23205130 Downregulation of miR-544 in tissue, but not in serum, is a novel biomarker of malignant transformation in glioma 9365 hsa-mir-200b Endometrial Neoplasms 23205572 MicroRNA-200b Is Overexpressed in Endometrial Adenocarcinomas and Enhances MMP2 Activity by Downregulating TIMP2 in Human Endometrial Cancer Cell Line HEC-1A Cells 9366 hsa-mir-133a-1 Urinary Bladder Neoplasms 23206218 MicroRNA-133 inhibits cell proliferation, migration and invasion by targeting epidermal growth factor receptor and its downstream effector proteins in bladder cancer 9367 hsa-mir-133a-2 Urinary Bladder Neoplasms 23206218 MicroRNA-133 inhibits cell proliferation, migration and invasion by targeting epidermal growth factor receptor and its downstream effector proteins in bladder cancer 9368 hsa-mir-133b Urinary Bladder Neoplasms 23206218 MicroRNA-133 inhibits cell proliferation, migration and invasion by targeting epidermal growth factor receptor and its downstream effector proteins in bladder cancer 9369 hsa-mir-141 Carcinoma, Renal Cell 23206420 A possible role for micro-RNA 141 down-regulation in sunitinib resistant metastatic clear cell renal cell carcinoma through induction of epithelial-to-mesenchymal transition and hypoxia resistance 9370 hsa-mir-375 Lung Neoplasms 23206448 miR-375 is a novel prognostic indicator in NSCLC and might be a potential target for diagnosis and gene therapy 9371 hsa-mir-7-1 Melanoma 23206698 miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling 9372 hsa-mir-7-2 Melanoma 23206698 miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling 9373 hsa-mir-7-3 Melanoma 23206698 miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling 9374 hsa-mir-10b Endometriosis 23206733 Targeting of syndecan-1 by micro-ribonucleic acid miR-10b modulates invasiveness of endometriotic cells via dysregulation of the proteolytic milieu and interleukin-6 secretion 9375 hsa-mir-21 Carcinoma, Renal Cell 23206776 miR-21 Downregulated TCF21 to Inhibit KISS1 in Renal Cancer 9376 hsa-mir-223 Osteosarcoma 23208072 Heat Shock Protein 90B1 Plays an Oncogenic Role and is a Target of microRNA-223 in Human Osteosarcoma 9377 hsa-mir-7-1 Colorectal Neoplasms 23208495 microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis 9378 hsa-mir-7-2 Colorectal Neoplasms 23208495 microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis 9379 hsa-mir-7-3 Colorectal Neoplasms 23208495 microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis 9380 hsa-mir-138-1 Leukemia, Myeloid 23208504 BCR-ABL/GATA1/miR-138 mini circuitry contributes to the leukemogenesis of chronic myeloid leukemia 9381 hsa-mir-138-2 Leukemia, Myeloid 23208504 BCR-ABL/GATA1/miR-138 mini circuitry contributes to the leukemogenesis of chronic myeloid leukemia 9382 hsa-mir-146a Myocardial Reperfusion Injury 23208587 Increased expression of microRNA-146a decreases myocardial ischaemia/reperfusion injury 9383 hsa-mir-142 Stomach Diseases 23209550 Overexpression of miR-142-5p and miR-155 in Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma Resistant to Helicobacter pylori Eradication 9384 hsa-mir-155 Stomach Diseases 23209550 Overexpression of miR-142-5p and miR-155 in Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma Resistant to Helicobacter pylori Eradication 9385 hsa-mir-200a Breast Neoplasms 23209748 miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression 9386 hsa-mir-200b Breast Neoplasms 23209748 miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression 9387 hsa-mir-200c Breast Neoplasms 23209748 miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression 9388 hsa-mir-98 Neoplasms 23211491 MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11 9389 hsa-mir-150 Cardiomegaly 23211718 miR-150 regulates high glucose-induced cardiomyocyte hypertrophy by targeting the transcriptional co-activator p300 9390 hsa-mir-205 Mouth Neoplasms 23212344 MicroRNA-205 directly regulates the tumor suppressor, interleukin-24, in human KB oral cancer cells 9391 hsa-mir-218-1 Medulloblastoma 23212916 MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype associated genes in medulloblastoma 9392 hsa-mir-218-2 Medulloblastoma 23212916 MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype associated genes in medulloblastoma 9393 hsa-mir-21 Breast Neoplasms 23216894 Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells 9394 hsa-mir-122 Hepatitis C 23218444 Can tobacco use promote HCV-induced miR-122 hijacking and hepatocarcinogenesis? 9395 hsa-mir-181a-1 Inflammation 23220232 miR-181a and inflammation: miRNA homeostasis response to inflammatory stimuli in vivo 9396 hsa-mir-181a-2 Inflammation 23220232 miR-181a and inflammation: miRNA homeostasis response to inflammatory stimuli in vivo 9397 hsa-mir-107 Glioma 23220650 P53-induced microRNA-107 inhibits proliferation of glioma cells and down-regulates the expression of CDK6 and Notch-2 9398 hsa-mir-150 Hypertension 23220912 Reduced miR-150 is Associated with Poor Survival in Pulmonary Arterial Hypertension 9399 hsa-mir-29b-1 Cicatrix 23221517 Identification of Collagen 1 as a Post-transcriptional Target of miR-29b in Skin Fibroblasts: Therapeutic Implication for Scar Reduction 9400 hsa-mir-29b-2 Cicatrix 23221517 Identification of Collagen 1 as a Post-transcriptional Target of miR-29b in Skin Fibroblasts: Therapeutic Implication for Scar Reduction 9401 hsa-mir-122 Hepatitis B 23221562 HBV mRNAs-mediated miR-122 inhibition up-regulates PTTG1-binding protein which promotes HCC tumor growth and cell invasion 9402 hsa-mir-146a Melanoma 23222547 The rs2910164 G>C polymorphism in microRNA-146a is associated with the incidence of malignant melanoma 9403 hsa-mir-145 Neuroblastoma 23222716 MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha 9404 hsa-mir-200a Carcinoma, Hepatocellular 23222811 Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma 9405 hsa-mir-200b Carcinoma, Hepatocellular 23222811 Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma 9406 hsa-mir-200c Carcinoma, Hepatocellular 23222811 Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma 9407 hsa-mir-193a Leukemia, Myeloid, Acute 23223432 Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21)acute myeloid leukemia by activating the PTEN/PI3K signal pathway 9408 hsa-mir-21 Inflammatory Bowel Diseases 23224068 PDCD4/miR-21 dysregulation in inflammatory bowel disease-associated carcinogenesis 9409 hsa-mir-30c-1 Breast Neoplasms 23224145 MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion. 9410 hsa-mir-30c-2 Breast Neoplasms 23224145 MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion. 9411 hsa-mir-21 Esophageal Neoplasms 23224754 Clinical impact of serum exosomal microRNA-21 as a clinical biomarker in human esophageal squamous cell carcinoma 9412 hsa-mir-449a Hepatitis C 23226395 Hepatitis C Virus Mediated Changes in miRNA-449a Modulates Inflammatory Biomarker YKL40 through Components of the NOTCH Signaling Pathway 9413 hsa-mir-16-1 Carcinoma, Hepatocellular 23226427 Cyclooxygenase-2 Is a Target of MicroRNA-16 in Human Hepatoma Cells 9414 hsa-mir-16-2 Carcinoma, Hepatocellular 23226427 Cyclooxygenase-2 Is a Target of MicroRNA-16 in Human Hepatoma Cells 9415 hsa-mir-182 Urinary Bladder Neoplasms 23226455 Oncogenic miRNA-182-5p Targets Smad4 and RECK in Human Bladder Cancer 9416 hsa-mir-21 Carcinoma, Endometrioid 23226804 microRNA-21 overexpression contributes to cell proliferation by targeting PTEN in endometrioid endometrial cancer 9417 hsa-mir-17 Glioma 23226946 Increased Expression of microRNA-17 Predicts Poor Prognosis in Human Glioma 9418 hsa-mir-7-1 Breast Neoplasms 23227519 An induction of microRNA, miR-7 through estrogen treatment in breast carcinoma 9419 hsa-mir-7-2 Breast Neoplasms 23227519 An induction of microRNA, miR-7 through estrogen treatment in breast carcinoma 9420 hsa-mir-7-3 Breast Neoplasms 23227519 An induction of microRNA, miR-7 through estrogen treatment in breast carcinoma 9421 hsa-mir-383 Medulloblastoma 23227829 MiR-383 is Downregulated in Medulloblastoma and Targets Peroxiredoxin 3 (PRDX3) 9422 hsa-mir-196a-1 Breast Neoplasms 23228090 Evaluation of single nucleotide polymorphisms in microRNAs (hsa-miR-196a2 rs11614913 C/T) from Brazilian women with breast cancer 9423 hsa-mir-196a-2 Breast Neoplasms 23228090 Evaluation of single nucleotide polymorphisms in microRNAs (hsa-miR-196a2 rs11614913 C/T) from Brazilian women with breast cancer 9424 hsa-mir-150 Carcinoma, Non-Small-Cell Lung 23228962 Expression of miR-150 and miR-3940-5p is reduced in non-small cell lung carcinoma and correlates with clinicopathological features 9425 hsa-mir-3940 Carcinoma, Non-Small-Cell Lung 23228962 Expression of miR-150 and miR-3940-5p is reduced in non-small cell lung carcinoma and correlates with clinicopathological features 9426 hsa-mir-24-1 Carcinoma, Hepatocellular 23229173 Human hepatocellular carcinoma cell-specific miRNAs reveal the differential expression of miR-24 and miR-27a in cirrhotic/non-cirrhotic HCC 9427 hsa-mir-24-2 Carcinoma, Hepatocellular 23229173 Human hepatocellular carcinoma cell-specific miRNAs reveal the differential expression of miR-24 and miR-27a in cirrhotic/non-cirrhotic HCC 9428 hsa-mir-27a Carcinoma, Hepatocellular 23229173 Human hepatocellular carcinoma cell-specific miRNAs reveal the differential expression of miR-24 and miR-27a in cirrhotic/non-cirrhotic HCC 9429 hsa-mir-1-1 Osteosarcoma 23229283 miRNA expression profile in human osteosarcoma: Role of miR-1 and miR-133b in proliferation and cell cycle control 9430 hsa-mir-1-2 Osteosarcoma 23229283 miRNA expression profile in human osteosarcoma: Role of miR-1 and miR-133b in proliferation and cell cycle control 9431 hsa-mir-133b Osteosarcoma 23229283 miRNA expression profile in human osteosarcoma: Role of miR-1 and miR-133b in proliferation and cell cycle control 9432 hsa-mir-18a Colonic Neoplasms 23229340 MicroRNA-18a upregulates autophagy and ataxia telangiectasia mutated gene expression in HCT116 colon cancer cells 9433 hsa-mir-335 Carcinoma, Hepatocellular 23229728 Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma 9434 hsa-mir-125b-1 Mouth Neoplasms 23230394 Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins 9435 hsa-mir-125b-2 Mouth Neoplasms 23230394 Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins 9436 hsa-mir-203 Mouth Neoplasms 23230394 Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins 9437 hsa-mir-21 Mouth Neoplasms 23230394 Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins 9438 hsa-mir-370 Mouth Neoplasms 23231387 miR-370 modulates insulin receptor substrate-1 expression and inhibits the tumor phenotypes of oral carcinoma 9439 hsa-mir-30d Prostatic Neoplasms 23231923 Identification of miR-30d as a novel prognostic maker of prostate cancer 9440 hsa-mir-335 Lung Neoplasms 23232114 Genetic variation in a miR-335 binding site in BIRC5 alters susceptibility to lung cancer in Chinese Han populations 9441 hsa-mir-200c Lymphoma, Large B-Cell, Diffuse 23232598 High expression of microRNA-200c predicts poor clinical outcome in diffuse large B-cell lymphoma 9442 hsa-mir-145 Stomach Neoplasms 23233482 microRNA-145 targets v-ets erythroblastosis virus E26 oncogene homolog 1 to suppress the invasion, metastasis and angiogenesis of gastric cancer cells 9443 hsa-mir-148b Breast Neoplasms 23233531 miR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS,and CSF1 9444 hsa-mir-31 Psoriasis 23233723 MicroRNA-31 Is Overexpressed in Psoriasis and Modulates Inflammatory Cytokine and Chemokine Production in Keratinocytes via Targeting Serine/Threonine Kinase 40 9445 hsa-mir-31 Prostatic Neoplasms 23233736 Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression 9446 hsa-mir-596 Mouth Neoplasms 23233740 Potential of tumor-suppressive miR-596 targeting LGALS3BP as a therapeutic agent in oral cancer 9447 hsa-mir-15a Ischemia 23233752 MicroRNA-15a and MicroRNA-16 Impair Human Circulating Proangiogenic Cell Functions and Are Increased in the Proangiogenic Cells and Serum of Patients With Critical Limb Ischemia 9448 hsa-mir-27a Leukemia, Myeloid, Acute 23236401 MiR-27a Functions as a Tumor Suppressor in Acute Leukemia by Regulating 14-3-3 9449 hsa-mir-195 Myocardial Infarction 23236408 Our results imply that the plasma concentration of miR-30a, miR-195 and let-7b can be potential indicators for AMI 9450 hsa-mir-30a Myocardial Infarction 23236408 Our results imply that the plasma concentration of miR-30a, miR-195 and let-7b can be potential indicators for AMI 9451 hsa-mir-21 Spinal Cord Injuries 23238710 microRNA-21 Regulates Astrocytic Response Following Spinal Cord Injury 9452 hsa-mir-10b Breast Neoplasms 23238818 The level of circulating miRNA-10b and miRNA-373 in detecting lymph node metastasis of breast cancer: potential biomarkers 9453 hsa-mir-373 Breast Neoplasms 23238818 The level of circulating miRNA-10b and miRNA-373 in detecting lymph node metastasis of breast cancer: potential biomarkers 9454 hsa-mir-155 Inflammation 23239035 microRNA-155 can be used as a potential biomarker or therapeutic in the autoimmune diseases,especially rheumatoid arthritis 9455 hsa-mir-92a-1 Neoplasms 23239404 Development of miR-92a delivery system for antiangiogenesis-based cancer therapy 9456 hsa-mir-92a-2 Neoplasms 23239404 Development of miR-92a delivery system for antiangiogenesis-based cancer therapy 9457 hsa-mir-205 Urinary Bladder Neoplasms 23239884 The p63 isoform deltaNp63α inhibits epithelial-mesenchymal transition in human bladder cancer cells: Role of miR205 9458 hsa-mir-27a Breast Neoplasms 23240057 MiR-27 as a Prognostic Marker for Breast Cancer Progression and Patient Survival 9459 hsa-mir-27b Breast Neoplasms 23240057 MiR-27 as a Prognostic Marker for Breast Cancer Progression and Patient Survival 9460 hsa-mir-181a-1 Breast Neoplasms 23241956 TGF-beta upregulates miR-181a expression to promote breast cancer metastasis 9461 hsa-mir-181a-2 Breast Neoplasms 23241956 TGF-beta upregulates miR-181a expression to promote breast cancer metastasis 9462 hsa-mir-372 Stomach Neoplasms 23242208 microRNA-372 maintains oncogene characteristics by targeting TNFAIP1 and affects NFkB signaling in human gastric carcinoma cells 9463 hsa-mir-218-1 Glioma 23243056 MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-kB activity 9464 hsa-mir-218-2 Glioma 23243056 MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-kB activity 9465 hsa-mir-34a Colonic Neoplasms 23243217 Detection of miR-34a Promoter Methylation in Combination with Elevated Expression of c-Met and beta-Catenin Predicts Distant Metastasis of Colon Cancer 9466 hsa-mir-190a Neuroblastoma 23245204 MiR-190 leads to aggressive phenotype of neuroblastoma through indirect activation of TrkB pathway 9467 hsa-mir-190b Neuroblastoma 23245204 MiR-190 leads to aggressive phenotype of neuroblastoma through indirect activation of TrkB pathway 9468 hsa-mir-29a Melanoma 23245396 Interferon-gamma-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells 9469 hsa-mir-29b-1 Melanoma 23245396 Interferon-gamma-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells 9470 hsa-mir-29b-2 Melanoma 23245396 Interferon-gamma-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells 9471 hsa-mir-122 Hepatitis C 23245472 MicroRNA-122-dependent and -independent replication of Hepatitis C Virus in Hep3B human hepatoma cells 9472 hsa-mir-17 Myelodysplastic Syndromes 23246221 Expression analysis of mir-17-5p, mir-20a and let-7a microRNAs and their target proteins in CD34+ bone marrow cells of patients with myelodysplastic syndromes 9473 hsa-mir-20a Myelodysplastic Syndromes 23246221 Expression analysis of mir-17-5p, mir-20a and let-7a microRNAs and their target proteins in CD34+ bone marrow cells of patients with myelodysplastic syndromes 9474 hsa-mir-25 Neoplasms 23246404 Downregulation of the Mitochondrial Calcium Uniporter by Cancer-Related miR-25 9475 hsa-mir-363 Head and Neck Neoplasms 23246488 Dysregulated miR-363 affects head and neck cancer invasion and metastasis by targeting podoplanin 9476 hsa-mir-27a Stomach Neoplasms 23246964 Genetic variations in miR-27a gene decrease mature miR-27a level and reduce gastric cancer susceptibility 9477 hsa-mir-21 Multiple Myeloma 23247593 Set9, NF-kB, and microRNA-21 mediate berberine-induced apoptosis of human multiple myeloma cells 9478 hsa-mir-122 Hepatitis C 23248316 Competing and noncompeting activities of miR-122 and the 5' exonuclease Xrn1 in regulation of hepatitis C virus replication 9479 hsa-mir-18a Glioblastoma 23249750 Targeting of TGFbeta signature and its essential component CTGF by miR-18 correlates with improved survival in glioblastoma 9480 hsa-mir-143 Glioma 23250070 Rapamycin inhibits human glioma cell proliferation through down-regulating mammalian target of rapamycin pathway and up-regulating microRNA-143 9481 hsa-mir-17 Colorectal Neoplasms 23250421 Elevated oncofoetal miR-17-5p expression regulates colorectal cancer progression by repressing its target gene P130 9482 hsa-mir-196a-1 Breast Neoplasms 23250869 A MicroRNA196a2* and TP63 Circuit Regulated by Estrogen Receptor-alpha and ERK2 that Controls Breast Cancer Proliferation and Invasiveness Properties 9483 hsa-mir-196a-2 Breast Neoplasms 23250869 A MicroRNA196a2* and TP63 Circuit Regulated by Estrogen Receptor-alpha and ERK2 that Controls Breast Cancer Proliferation and Invasiveness Properties 9484 hsa-mir-124-1 Breast Neoplasms 23250910 MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer 9485 hsa-mir-124-2 Breast Neoplasms 23250910 MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer 9486 hsa-mir-124-3 Breast Neoplasms 23250910 MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer 9487 hsa-mir-155 Diabetes Complications 23250986 Global Remodeling of the Vascular Stem Cell Niche in Bone Marrow of Diabetic Patients: Implication of the miR-155/FOXO3a Signaling Pathway 9488 hsa-mir-145 Choriocarcinoma 23251245 Cell proliferation and invasion ability of human choriocarcinoma cells lessened due to inhibition of Sox2 expression by microRNA-145 9489 hsa-mir-125b-1 HIV-1 23251514 Cocaine Enhances HIV-1 Replication in CD4+ T Cells by Down-Regulating MiR-125b 9490 hsa-mir-125b-2 HIV-1 23251514 Cocaine Enhances HIV-1 Replication in CD4+ T Cells by Down-Regulating MiR-125b 9491 hsa-mir-137 Oligodendroglioma 23252729 MIR-137 Suppresses Growth and Invasion, is Downregulated in Oligodendroglial Tumors and Targets CSE1L 9492 hsa-mir-182 Glioma 23252827 The miR-183/96/182 Cluster Regulates Oxidative Apoptosis and Sensitizes Cells to Chemotherapy in Gliomas 9493 hsa-mir-183 Glioma 23252827 The miR-183/96/182 Cluster Regulates Oxidative Apoptosis and Sensitizes Cells to Chemotherapy in Gliomas 9494 hsa-mir-96 Glioma 23252827 The miR-183/96/182 Cluster Regulates Oxidative Apoptosis and Sensitizes Cells to Chemotherapy in Gliomas 9495 hsa-mir-29b-1 Multiple Myeloma 23254643 miR-29b negatively regulates human osteoclastic cell differentiation and function: Implications for the treatment of multiple myeloma-related bone disease 9496 hsa-mir-29b-2 Multiple Myeloma 23254643 miR-29b negatively regulates human osteoclastic cell differentiation and function: Implications for the treatment of multiple myeloma-related bone disease 9497 hsa-mir-24-1 Glioma 23254855 miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1 9498 hsa-mir-24-2 Glioma 23254855 miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1 9499 hsa-mir-27a Glioma 23254855 miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1 9500 hsa-mir-27a Ovarian Neoplasms 23254909 The microRNA-27a: ZBTB10-specificity protein pathway is involved in follicle stimulating hormone-induced VEGF, Cox2 and survivin expression in ovarian epithelial cancer cells 9501 hsa-mir-218-1 Colonic Neoplasms 23255074 MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating oncogene BMI-1 9502 hsa-mir-218-2 Colonic Neoplasms 23255074 MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating oncogene BMI-1 9503 hsa-mir-491 Cerebral Infarction 23257658 A functional polymorphism at miR-491-5p binding site in the 3'-UTR of MMP-9 gene confers increased risk for atherosclerotic cerebral infarction in a Chinese population 9504 hsa-mir-31 Colonic Neoplasms 23258531 miR-31 acts as an oncogene in colon cancer and identified RhoBTB1 as a new target of miR-31 further study demonstrated that miR-31 contributed to the development of colon cancer at least partly by targeting RhoBTB1 9505 hsa-mir-21 Laryngeal Neoplasms 23259291 Expression of mir-21 and mir-375 in laryngeal squamous cell carcinoma 9506 hsa-mir-375 Laryngeal Neoplasms 23259291 Expression of mir-21 and mir-375 in laryngeal squamous cell carcinoma 9507 hsa-mir-16-1 Leukemia-Lymphoma, Adult T-Cell 23260326 Micro-RNA-16 expression in paraffin-embedded specimen correlates with overall survival of T-lymphoblastic lymphoma/leukemia 9508 hsa-mir-16-2 Leukemia-Lymphoma, Adult T-Cell 23260326 Micro-RNA-16 expression in paraffin-embedded specimen correlates with overall survival of T-lymphoblastic lymphoma/leukemia 9509 hsa-mir-182 Ovarian Neoplasms 23262295 The upregulation of signal transducer and activator of transcription 5-dependent microRNA-182 and microRNA-96 promotes ovarian cancer cell proliferation by targeting forkhead box O3 upon leptin stimulation 9510 hsa-mir-96 Ovarian Neoplasms 23262295 The upregulation of signal transducer and activator of transcription 5-dependent microRNA-182 and microRNA-96 promotes ovarian cancer cell proliferation by targeting forkhead box O3 upon leptin stimulation 9511 hsa-mir-424 Hypertension 23263626 An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension 9512 hsa-mir-503 Hypertension 23263626 An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension 9513 hsa-mir-183 Glioma 23263745 MicroRNA-183 upregulates HIF-1a by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells 9514 hsa-mir-17 Lung Neoplasms 23263848 miR-17-5p may be potential biomarker for prediction the prognosis in patients with lung cancer. 9515 hsa-mir-224 Glioma 23263909 Upregulation of microRNA-224 confers a poor prognosis in glioma patients 9516 hsa-mir-34a Stomach Neoplasms 23264087 Expression and regulatory function of miRNA-34a in targeting survivin in gastric cancer cells 9517 hsa-mir-146b Thyroid Neoplasms 23264400 Prognostic Implications of miR-146b Expression and Its Functional Role in Papillary Thyroid Carcinoma 9518 hsa-mir-501 Hepatitis B 23266610 MicroRNA-501 promotes HBV replication by targeting HBXIP 9519 hsa-mir-146a Behcet Syndrome 23268366 MicroRNA-146a and Ets-1 gene polymorphisms in ocular Behcet's disease and Vogt-Koyanagi-Harada syndrome 9520 hsa-mir-100 Urinary Bladder Neoplasms 23270926 MicroRNA-100 inhibits human bladder urothelial carcinogenesis by directly targeting mTOR 9521 hsa-mir-885 Head and Neck Neoplasms 23271051 A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer 9522 hsa-mir-149 Neoplasms, Squamous Cell 23272122 The Association between Genetic Polymorphism and the Processing Efficiency of miR-149 Affects the Prognosis of Patients with Head and Neck Squamous Cell Carcinoma 9523 hsa-mir-21 Prostatic Neoplasms 23272133 Resveratrol Reduces Prostate Cancer Growth and Metastasis by Inhibiting the Akt/MicroRNA-21 Pathway 9524 hsa-mir-200a Ovarian Neoplasms 23272653 Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer 9525 hsa-mir-200b Ovarian Neoplasms 23272653 Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer 9526 hsa-mir-200c Ovarian Neoplasms 23272653 Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer 9527 hsa-mir-30d Neoplasms 23274497 mir-30d Regulates multiple genes in the autophagy pathway and impairs autophagy process in human cancer cells 9528 hsa-mir-137 Colorectal Neoplasms 23275153 Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer 9529 hsa-mir-21 Lymphoma, Large B-Cell, Diffuse 23275230 MicroRNA-21 regulates the sensitivity of diffuse large B-cell lymphoma cells to the CHOP chemotherapy regimen 9530 hsa-mir-143 Esophageal Neoplasms 23276710 miR-143 may act as a tumor suppressor in ESCC 9531 hsa-mir-18a Arthritis, Rheumatoid 23280137 The TNFa-induced miR-18a activates rheumatoid arthritis synovial fibroblasts through a feedback loop in NF-κB signaling 9532 hsa-mir-362 Colorectal Neoplasms 23280316 MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer 9533 hsa-mir-140 Osteoarthritis 23281373 Detection of the expression level of miR-140 using realtime fluorescent quantitative PCR in knee synovial fluid of osteoarthritis patients 9534 hsa-mir-7-1 Parkinson Disease 23281385 MiR-7 variation is not associated with PD in Chinese patients 9535 hsa-mir-7-2 Parkinson Disease 23281385 MiR-7 variation is not associated with PD in Chinese patients 9536 hsa-mir-7-3 Parkinson Disease 23281385 MiR-7 variation is not associated with PD in Chinese patients 9537 hsa-mir-182 Urinary Bladder Neoplasms 23284967 Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells 9538 hsa-mir-183 Urinary Bladder Neoplasms 23284967 Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells 9539 hsa-mir-210 Urinary Bladder Neoplasms 23284967 Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells 9540 hsa-mir-96 Urinary Bladder Neoplasms 23284967 Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells 9541 hsa-mir-29a Hepatitis B 23285022 MicroRNA-29a-5p Is a Novel Predictor for Early Recurrence of Hepatitis B Virus-Related Hepatocellular Carcinoma after Surgical Resection 9542 hsa-mir-204 Neoplasms 23285024 Genomic Loss of Tumor Suppressor miRNA-204 Promotes Cancer Cell Migration and Invasion by Activating AKT/mTOR/Rac1 Signaling and Actin Reorganization 9543 hsa-mir-126 Colitis, Ulcerative 23285182 Up-Regulation of microRNA-126 May Contribute to Pathogenesis of Ulcerative Colitis via Regulating NF-kappaB Inhibitor IκBα 9544 hsa-mir-15b Fatty Liver 23287814 Upregulation of miR-15b in NAFLD models and in the serum of patients with fatty liver disease 9545 hsa-mir-155 Inflammatory Bowel Diseases 23288924 OVER EXPRESSION OF MICRORNAS-155 AND 21 TARGETING MISMATCH REPAIR PROTEINS IN INFLAMMATORY BOWEL DISEASES 9546 hsa-mir-21 Inflammatory Bowel Diseases 23288924 OVER EXPRESSION OF MICRORNAS-155 AND 21 TARGETING MISMATCH REPAIR PROTEINS IN INFLAMMATORY BOWEL DISEASES 9547 hsa-mir-9-1 Nasopharyngeal Neoplasms 23291181 miR-9 modulates the expression of interferon-regulated genes and MHC class I molecules in human nasopharyngeal carcinoma cells 9548 hsa-mir-9-2 Nasopharyngeal Neoplasms 23291181 miR-9 modulates the expression of interferon-regulated genes and MHC class I molecules in human nasopharyngeal carcinoma cells 9549 hsa-mir-372 Carcinoma, Hepatocellular 23291979 Upregulation of microRNA-372 associates with tumor progression and prognosis in hepatocellular carcinoma 9550 hsa-mir-34a Neoplasms 23292172 Oncolytic adenovirus co-expressing miRNA-34a and IL-24 induces superior antitumor activity in experimental tumor model 9551 hsa-mir-146a Hepatitis B 23292505 Association of a single-nucleotide polymorphism within the miR-146a gene with susceptibility for acute-on-chronic hepatitis B liver failure 9552 hsa-mir-100 Esophageal Neoplasms 23292834 MicroRNA-99a/100 promotes apoptosis by targeting mTOR in human esophageal squamous cell carcinoma 9553 hsa-mir-99a Esophageal Neoplasms 23292834 MicroRNA-99a/100 promotes apoptosis by targeting mTOR in human esophageal squamous cell carcinoma 9554 hsa-mir-326 Glioma 23292865 Down-regulation of miR-326 may have potential value for predicting clinical outcomes in glioma patients with high pathological grades, suggesting that miR-326 is an important candidate tumor suppressor, and its down-regulated expression may contribute to glioma progression 9555 hsa-mir-199a-1 Colorectal Neoplasms 23292866 miR-199a-3p may serve as an efficient biomarker for diagnosis and novel prognostic indicator in colorectal cancer 9556 hsa-mir-199a-2 Colorectal Neoplasms 23292866 miR-199a-3p may serve as an efficient biomarker for diagnosis and novel prognostic indicator in colorectal cancer 9557 hsa-mir-34a Breast Neoplasms 23292869 Downregulation of miR-34a in breast tumors is not associated with either p53 mutations or promoter hypermethylation while it correlates with metastasis 9558 hsa-mir-196b Endometriosis 23293219 miR-196b targets c-myc and Bcl-2 expression, inhibits proliferation and induces apoptosis in endometriotic stromal cells 9559 hsa-mir-146a Psychotic Disorders 23295264 Down-regulation of inflammation-protective microRNAs 146a and 212 in monocytes of patients with postpartum psychosis 9560 hsa-mir-212 Psychotic Disorders 23295264 Down-regulation of inflammation-protective microRNAs 146a and 212 in monocytes of patients with postpartum psychosis 9561 hsa-mir-200a Endometrial Neoplasms 23295740 Tamoxifen Represses miR-200 MicroRNAs and Promotes Epithelial-to-Mesenchymal Transition by Up-Regulating c-Myc in Endometrial Carcinoma Cell Lines 9562 hsa-mir-200b Endometrial Neoplasms 23295740 Tamoxifen Represses miR-200 MicroRNAs and Promotes Epithelial-to-Mesenchymal Transition by Up-Regulating c-Myc in Endometrial Carcinoma Cell Lines 9563 hsa-mir-200c Endometrial Neoplasms 23295740 Tamoxifen Represses miR-200 MicroRNAs and Promotes Epithelial-to-Mesenchymal Transition by Up-Regulating c-Myc in Endometrial Carcinoma Cell Lines 9564 hsa-mir-133b Stomach Neoplasms 23296701 miR-133b acts as a tumor suppressor and negatively regulates FGFR1 in gastric cancer 9565 hsa-mir-199b Breast Neoplasms 23296799 MiR-199b-5p targets HER2 in breast cancer cells 9566 hsa-mir-182 Ovarian Neoplasms 23296900 MicroRNA-182 promotes cell growth, invasion and chemoresistance by targeting programmed cell death 4 (PDCD4) in human ovarian carcinomas 9567 hsa-mir-149 Glioma 23298478 MicroRNA-149 inhibits proliferation and invasion of glioma cells via blockade of AKT1 signaling 9568 hsa-mir-99a Glioblastoma 23298836 The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma 9569 hsa-mir-107 Glioma 23299462 MicroRNA-107 inhibits glioma cell migration and invasion by modulating Notch2 expression 9570 hsa-mir-23b Prostatic Neoplasms 23300597 The microRNA -23b/-27b Cluster Suppresses the Metastatic Phenotype of Castration-Resistant Prostate Cancer Cells 9571 hsa-mir-27b Prostatic Neoplasms 23300597 The microRNA -23b/-27b Cluster Suppresses the Metastatic Phenotype of Castration-Resistant Prostate Cancer Cells 9572 hsa-mir-138-1 Neoplasms 23300839 MicroRNA-138 Suppresses Neutrophil Gelatinase-Associated Lipocalin Expression and Inhibits Tumorigenicity 9573 hsa-mir-138-2 Neoplasms 23300839 MicroRNA-138 Suppresses Neutrophil Gelatinase-Associated Lipocalin Expression and Inhibits Tumorigenicity 9574 hsa-mir-150 Esophageal Neoplasms 23301507 MiR-150 regulates the EMT-inducer ZEB1 in esophageal squamous cell carcinoma.Wound healing assays of premiR-150-treated esophageal squamous cell carcinoma TE-8 cells 9575 hsa-mir-16-1 Ovarian Neoplasms 23302126 MicroRNA-16 regulates the proliferation, invasion and apoptosis of ovarian epithelial carcinoma cells in vitro 9576 hsa-mir-16-2 Ovarian Neoplasms 23302126 MicroRNA-16 regulates the proliferation, invasion and apoptosis of ovarian epithelial carcinoma cells in vitro 9577 hsa-mir-130a Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients 9578 hsa-mir-155 Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients 9579 hsa-mir-210 Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients 9580 hsa-mir-326 Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients 9581 hsa-mir-329-1 Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients 9582 hsa-mir-329-2 Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients 9583 hsa-mir-323a Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients 9584 hsa-mir-323b Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients 9585 hsa-mir-155 Breast Neoplasms 23302487 miR-155, as an oncomir, promotes lymph node involvement and vascular invasion and accompanies over-expressed HER-2 on breast cancer FFPE tissue 9586 hsa-mir-210 Heart Failure 23302636 MicroRNA 210 as a Biomarker for Congestive Heart Failure 9587 hsa-mir-34b Pancreatic Neoplasms 23305226 MicroRNA-34b inhibits pancreatic cancer metastasis through repressing Smad3 9588 hsa-mir-125b-1 Lupus Erythematosus, Systemic 23305626 Further analysis showed that the down-regulation of miR-125b, mainly in T cells, was negatively correlated with lupus nephritis 9589 hsa-mir-125b-2 Lupus Erythematosus, Systemic 23305626 Further analysis showed that the down-regulation of miR-125b, mainly in T cells, was negatively correlated with lupus nephritis 9590 hsa-mir-636 Carcinoma, Hepatocellular 23306701 ANT2 suppression by shRNA restores miR-636 expression, thereby downregulating Ras and inhibiting tumorigenesis of hepatocellular carcinoma 9591 hsa-mir-146a Colorectal Neoplasms 23306950 A genetic variant in miR-146a modifies colorectal cancer susceptibility in a chinese population 9592 hsa-mir-129-1 Stomach Neoplasms 23307240 Gastric juice miR-129 as a potential biomarker for screening gastric cancer 9593 hsa-mir-129-2 Stomach Neoplasms 23307240 Gastric juice miR-129 as a potential biomarker for screening gastric cancer 9594 hsa-mir-10b Glioblastoma 23307328 Inhibition of miR-10b strongly reduced cell invasion and migration in glioblastoma cell and stem cell lines while overexpression of miR-10b induced cell migration and invasion 9595 hsa-mir-16-1 Colonic Neoplasms 23308284 The Induction of microRNA-16 in Colon Cancer Cells by Protein Arginine Deiminase Inhibition Causes a p53-Dependent Cell Cycle Arrest 9596 hsa-mir-16-2 Colonic Neoplasms 23308284 The Induction of microRNA-16 in Colon Cancer Cells by Protein Arginine Deiminase Inhibition Causes a p53-Dependent Cell Cycle Arrest 9597 hsa-mir-145 Endometriosis 23312222 MicroRNA miR-145 inhibits proliferation, invasiveness, and stem cell phenotype of an in vitro endometriosis model by targeting multiple cytoskeletal elements and pluripotency factors 9598 hsa-mir-182 Uterine Cervical Neoplasms 23313739 MicroRNA-182 plays an onco-miRNA role in cervical cancer 9599 hsa-mir-34a Osteosarcoma 23314380 miR-34a inhibits the metastasis of osteosarcoma cells by repressing the expression of CD44. 9600 hsa-mir-34b Neoplasms 23314612 MicroRNA-34b functions as a tumor suppressor and acts as a nodal point in the feedback loop with Met 9601 hsa-mir-384 Myocardial Ischemia 23315007 MicroRNA-384-5p regulates ischemia-induced cardioprotection by targeting phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (PI3Kp110δ) 9602 hsa-mir-155 Carcinoma, Hepatocellular 23316018 These results suggest that S100A4 exerts its effects through the regulation of miR-155 expression in HCC cells 9603 hsa-mir-30b Vascular Calcification 23316327 Bone Morphogenetic Protein-2 Decreases MicroRNA-30b and MicroRNA-30c to Promote Vascular Smooth Muscle Cell Calcification 9604 hsa-mir-30c-1 Vascular Calcification 23316327 Bone Morphogenetic Protein-2 Decreases MicroRNA-30b and MicroRNA-30c to Promote Vascular Smooth Muscle Cell Calcification 9605 hsa-mir-30c-2 Vascular Calcification 23316327 Bone Morphogenetic Protein-2 Decreases MicroRNA-30b and MicroRNA-30c to Promote Vascular Smooth Muscle Cell Calcification 9606 hsa-mir-30c-1 Neoplasms 23318178 Sulfuretin-induced miR-30C selectively downregulates cyclin D1 and D2 and triggers cell death in human cancer cell lines 9607 hsa-mir-30c-2 Neoplasms 23318178 Sulfuretin-induced miR-30C selectively downregulates cyclin D1 and D2 and triggers cell death in human cancer cell lines 9608 hsa-mir-152 Ovarian Neoplasms 23318422 MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine 9609 hsa-mir-185 Ovarian Neoplasms 23318422 MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine 9610 hsa-mir-200a Breast Neoplasms 23318438 WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells 9611 hsa-mir-200b Breast Neoplasms 23318438 WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells 9612 hsa-mir-200c Breast Neoplasms 23318438 WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells 9613 hsa-mir-199a-1 Carcinoma, Hepatocellular 23319430 Propofol induces apoptosis of hepatocellular carcinoma cells by upregulation of microRNA-199a expression 9614 hsa-mir-199a-2 Carcinoma, Hepatocellular 23319430 Propofol induces apoptosis of hepatocellular carcinoma cells by upregulation of microRNA-199a expression 9615 hsa-mir-221 Carcinoma, Hepatocellular 23320393 Increased MiR-221 expression in hepatocellular carcinoma tissues and its role in enhancing cell growth and inhibiting apoptosis in vitro 9616 hsa-mir-218-1 Uterine Cervical Neoplasms 23320911 The pri-miR-218 rs11134527 SNP was significantly associated with the risk of cervical carcinoma in Eastern Chinese women 9617 hsa-mir-218-2 Uterine Cervical Neoplasms 23320911 The pri-miR-218 rs11134527 SNP was significantly associated with the risk of cervical carcinoma in Eastern Chinese women 9618 hsa-mir-21 Osteosarcoma 23321165 Identification of Serum MicroRNA-21 as a Biomarker for Chemosensitivity and Prognosis in Human Osteosarcoma 9619 hsa-mir-124-1 Carcinoma, Renal Cell 23321515 Hsa-mir-124-3 CpG island methylation is associated with advanced tumours and disease recurrence of patients with clear cell renal cell carcinoma 9620 hsa-mir-124-2 Carcinoma, Renal Cell 23321515 Hsa-mir-124-3 CpG island methylation is associated with advanced tumours and disease recurrence of patients with clear cell renal cell carcinoma 9621 hsa-mir-124-3 Carcinoma, Renal Cell 23321515 Hsa-mir-124-3 CpG island methylation is associated with advanced tumours and disease recurrence of patients with clear cell renal cell carcinoma 9622 hsa-mir-143 Prostatic Neoplasms 23321517 Mir143 expression inversely correlates with nuclear ERK5 immunoreactivity in clinical prostate cancer 9623 hsa-mir-374a Breast Neoplasms 23321667 MicroRNA-374a activates Wnt/beta-catenin signaling to promote breast cancer metastasis 9624 hsa-mir-18a Stomach Neoplasms 23322197 MicroRNA-18a modulates STAT3 activity through negative regulation of PIAS3 during gastric adenocarcinogenesis 9625 hsa-mir-31 Colorectal Neoplasms 23322774 MicroRNA-31 activates the Ras pathway and functions as an oncogenic microRNA in human colorectal cancer by repressing RAS p21 GTPase activating protein 1(RASA1). 9626 hsa-mir-126 Atherosclerosis 23324496 whereas the endothelial cell-specific miRNA-126 signals the need for endothelial repair through its transfer from apoptotic endothelial cells in microvesicles 9627 hsa-mir-145 Atherosclerosis 23324496 Downregulation of miR-145, which controls differentiation of smooth muscle cells, promotes lesion formation 9628 hsa-mir-155 Atherosclerosis 23324496 Elevated miR-155 levels are characteristic of proinflammatory macrophages and atherosclerotic lesions 9629 hsa-mir-125a Colonic Neoplasms 23327190 miR-125a/b Regulates the Activation of Cancer Stem Cells in Paclitaxel-resistant Colon Cancer 9630 hsa-mir-125b-1 Colonic Neoplasms 23327190 miR-125a/b Regulates the Activation of Cancer Stem Cells in Paclitaxel-resistant Colon Cancer 9631 hsa-mir-125b-2 Colonic Neoplasms 23327190 miR-125a/b Regulates the Activation of Cancer Stem Cells in Paclitaxel-resistant Colon Cancer 9632 hsa-mir-122 Infertility, Male 23327642 MicroRNA-122 influences the development of sperm abnormalities from human induced pluripotent stem cells by regulating TNP2 expression. 9633 hsa-mir-34a Choriocarcinoma 23327670 MiR-34a was either inhibited or ectopically expressed transiently in two choriocarcinoma cell lines (BeWo and JEG-3) respectively. 9634 hsa-mir-708 Breast Neoplasms 23328481 Our findings uncover a mechanistic role for miR-708 in metastasis and provide arationale for developing miR-708 as a therapeutic agent against metastatic breast cancer. 9635 hsa-mir-135b Stomach Neoplasms 23328512 Quantitative real-time PCR was used to validate the reliability of microarray and detect miR-135b expression in the above clinical samples, as well as cell lines GES-1, BGC-823 and SGC-7901. 9636 hsa-mir-211 Pancreatic Neoplasms 23329235 Clinical impact of circulating miR-221 in plasma of patients with pancreatic cancer 9637 hsa-mir-182 Prostatic Neoplasms 23329838 MicroRNA-182 and microRNA-200a control G-protein subunit alpha-13 (GNA13) expression and cell invasion synergistically in prostate cancer cells. 9638 hsa-mir-200a Prostatic Neoplasms 23329838 MicroRNA-182 and microRNA-200a control G-protein subunit alpha-13 (GNA13) expression and cell invasion synergistically in prostate cancer cells. 9639 hsa-mir-370 Neoplasms 23333300 Stat3 inhibits WTX expression through up-regulation of microRNA-370 in Wilms tumor 9640 hsa-mir-182 Breast Neoplasms 23333633 Up-regulation of miR-182 by beta-catenin in breast cancer increases tumorigenicity and invasiveness by targeting the matrix metalloproteinase inhibitor RECK 9641 hsa-mir-195 Stomach Neoplasms 23333942 MicroRNA-195 and microRNA-378 mediate tumor growth suppression by epigenetical regulation in gastric cancer 9642 hsa-mir-378a Stomach Neoplasms 23333942 MicroRNA-195 and microRNA-378 mediate tumor growth suppression by epigenetical regulation in gastric cancer 9643 hsa-mir-124-1 Pancreatic Neoplasms 23334332 Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1 9644 hsa-mir-124-2 Pancreatic Neoplasms 23334332 Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1 9645 hsa-mir-124-3 Pancreatic Neoplasms 23334332 Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1 9646 hsa-mir-193b Neoplasms 23335975 MicroRNA-193b enhances tumor progression via down regulation of neurofibromin 1 9647 hsa-mir-133b Lung Neoplasms 23337359 serum;Alteration of serum miR-206 and miR-133b is associated with lung carcinogenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone 9648 hsa-mir-206 Lung Neoplasms 23337359 serum;Alteration of serum miR-206 and miR-133b is associated with lung carcinogenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone 9649 hsa-mir-330 Colorectal Neoplasms 23337504 miR-330 regulates the proliferation of colorectal cancer cells by targeting Cdc42 9650 hsa-mir-199a-1 Breast Neoplasms 23337876 our data identify miR-199a-5p as a novel and unique regulator of autophagy, which plays an important role in cancer biology and cancer therapy 9651 hsa-mir-199a-2 Breast Neoplasms 23337876 our data identify miR-199a-5p as a novel and unique regulator of autophagy, which plays an important role in cancer biology and cancer therapy 9652 hsa-mir-214 Uterine Cervical Neoplasms 23337879 MiR-214 reduces cell survival and enhances cisplatin-induced cytotoxicity via down-regulation of Bcl2l2 in cervical cancer cells 9653 hsa-mir-301a Stomach Neoplasms 23338485 Overexpressed miR-301a promotes cell proliferation and invasion by targeting RUNX3 in gastric cancer 9654 hsa-mir-106b Lung Diseases 23338559 plasma;Clinical relevance of plasma miR-106b levels in patients with chronic obstructive pulmonary disease 9655 hsa-mir-23b Breast Neoplasms 23338610 Pro-oncogenic factors miR-23b- and miR-27b are regulated by Her2/Neu, EGF, and TNFa in breast cancer 9656 hsa-mir-145 Hypertension 23339529 Overexpression of microRNA-145 in atherosclerotic plaques from hypertensive patients 9657 hsa-mir-200a Breast Neoplasms 23340296 MicroRNA-200a Promotes Anoikis Resistance and Metastasis by Targeting YAP1 in Human Breast Cancer 9658 hsa-mir-30c-1 Breast Neoplasms 23340433 MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11 9659 hsa-mir-30c-2 Breast Neoplasms 23340433 MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11 9660 hsa-mir-146a Influenza, Human 23343627 Host microRNA molecular signatures associated with human H1N1 and H3N2 influenza A viruses reveal an unanticipated antiviral activity for miR-146a 9661 hsa-mir-138-1 Lung Neoplasms 23343715 MiR-138 Inhibits Tumor Growth Through Repression of EZH2 in Non-Small Cell Lung Cancer 9662 hsa-mir-138-2 Lung Neoplasms 23343715 MiR-138 Inhibits Tumor Growth Through Repression of EZH2 in Non-Small Cell Lung Cancer 9663 hsa-mir-133a-2 Myocardial Infarction 23347612 Circulating;Circulating miR-133a and miR-423-5p fail as biomarkers for left ventricular remodeling after myocardial infarction 9664 hsa-mir-423 Myocardial Infarction 23347612 Circulating;Circulating miR-133a and miR-423-5p fail as biomarkers for left ventricular remodeling after myocardial infarction 9665 hsa-mir-206 Stomach Neoplasms 23348698 MiR-206 inhibits gastric cancer proliferation in part by repressing CyclinD2 9666 hsa-mir-30a Glioma 23348703 PRDM1 is directly targeted by miR-30a-5p and modulates the Wnt/beta-catenin pathway in a Dkk1-dependent manner during glioma growth 9667 hsa-mir-34a Lung Neoplasms 23349340 Ectopic expression of miR-34a enhances radiosensitivity of non-small cell lung cancer cells, partly by suppressing the LyGDI signaling pathway 9668 hsa-mir-22 Huntington Disease 23349832 MicroRNA-22 (miR-22) Overexpression Is Neuroprotective via General Anti-Apoptotic Effects and May also Target Specific Huntington's Disease-Related Mechanisms 9669 hsa-mir-15a Neoplasms 23353574 Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines 9670 hsa-mir-21 Prostatic Neoplasms 23353719 miR-21, miR-221 and miR-222 expression and prostate cancer recurrence among obese and non-obese cases 9671 hsa-mir-221 Prostatic Neoplasms 23353719 miR-21, miR-221 and miR-222 expression and prostate cancer recurrence among obese and non-obese cases 9672 hsa-mir-222 Prostatic Neoplasms 23353719 miR-21, miR-221 and miR-222 expression and prostate cancer recurrence among obese and non-obese cases 9673 hsa-mir-296 Stomach Neoplasms 23353818 MicroRNA-296-5p increases proliferation in gastric cancer through repression of Caudal-related homeobox 1 9674 hsa-mir-155 Breast Neoplasms 23353819 Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cance 9675 hsa-mir-93 Colorectal Neoplasms 23354160 the downregulation of miR-93 was significantly correlated with unfavorable clinicopathologic features and short overall survival in patients with colon cancer, suggesting that decreased expression of miR-93 be used as a novel prognostic factor for this disease 9676 hsa-mir-29b-1 Neoplasms 23354167 GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating?microRNA-29b expression 9677 hsa-mir-29b-2 Neoplasms 23354167 GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating?microRNA-29b expression 9678 hsa-mir-199a-1 Neoplasms 23354452 MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines 9679 hsa-mir-199a-2 Neoplasms 23354452 MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines 9680 hsa-mir-199b Neoplasms 23354452 MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines 9681 hsa-mir-198 Lung Neoplasms 23354517 Circulating;Downregulation of cell-free miR-198 as a diagnostic biomarker for lung adenocarcinoma-associated malignant pleural effusion 9682 hsa-mir-34a Colorectal Neoplasms 23355243 The down-regulated expression of miR-34a in colorectal cancer patients is associated with recurrence after radical operation 9683 hsa-mir-145 Prostatic Neoplasms 23355420 HEF1 promotes epithelial mesenchymal transition and bone invasion in prostate cancer under the regulation of microRNA-145 9684 hsa-mir-21 Liver Neoplasms 23355454 microRNA 21-mediated suppression of Sprouty1 by Pokemon affects liver cancer cell growth and proliferation 9685 hsa-mir-132 HIV-1 23357732 miR-132 enhances HIV-1 replication 9686 hsa-mir-21 Pancreatic Neoplasms 23359184 Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression 9687 hsa-mir-214 Cardiomyopathies 23360823 TWIST1 regulates the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy 9688 hsa-mir-199a-1 Cardiomyopathies 23360823 TWIST1 regulates the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy 9689 hsa-mir-199a-2 Cardiomyopathies 23360823 TWIST1 regulates the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy 9690 hsa-mir-199b Cardiomyopathies 23360823 TWIST1 regulates the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy 9691 hsa-mir-1246 Esophageal Neoplasms 23361059 Serum;Serum microRNA expression profile: miR-1246 as a novel diagnostic and prognostic biomarker for oesophageal squamous cell carcinoma 9692 hsa-mir-34a Neoplasms 23361983 Modeling miRNA Regulation in Cancer Signaling Systems: miR-34a Regulation of the p53/Sirt1 Signaling Module 9693 hsa-mir-520a Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women 9694 hsa-mir-520b Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women 9695 hsa-mir-520c Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women 9696 hsa-mir-520d Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women 9697 hsa-mir-520e Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women 9698 hsa-mir-520f Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women 9699 hsa-mir-520g Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women 9700 hsa-mir-520h Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women 9701 hsa-mir-31 Breast Neoplasms 23364795 microRNA-31 sensitizes human breast cells to apoptosis by direct targeting of protein kinase C epsilon 9702 hsa-mir-18b Melanoma 23365201 The Role of miR-18b in MDM2-p53 Pathway Signaling and Melanoma Progression 9703 hsa-mir-451a Glioblastoma 23367447 A computational multiscale model of glioblastoma growth: Regulation of cell migration and proliferation via microRNA-451, LKB1 and AMPK 9704 hsa-mir-155 Breast Neoplasms 23372341 serum;miR-205 was down-regulated and miR-155 was up-regulated in BC patient serum 9705 hsa-mir-205 Breast Neoplasms 23372341 serum;miR-205 was down-regulated and miR-155 was up-regulated in BC patient serum 9706 hsa-mir-221 Osteosarcoma 23372675 MicroRNA-221 Induces Cell Survival and Cisplatin Resistance through PI3K/Akt Pathway in Human Osteosarcoma 9707 hsa-mir-150 Sepsis 23372743 Circulating;Circulating MicroRNA-150 Serum Levels Predict Survival in Patients with Critical Illness and Sepsis 9708 hsa-mir-100 Pancreatic Neoplasms 23373509 MicroRNA-100 regulates IGF1-receptor expression in metastatic pancreatic cancer cells 9709 hsa-mir-122 Liver Neoplasms 23373973 Effect of miR-122 and its target gene cationic amino acid transporter 1 on colorectal liver metastasis 9710 hsa-mir-376a-1 Retinoblastoma 23373993 Arsenic trioxide induced apoptosis in retinoblastoma cells by abnormal expression of microRNA-376a 9711 hsa-mir-376a-2 Retinoblastoma 23373993 Arsenic trioxide induced apoptosis in retinoblastoma cells by abnormal expression of microRNA-376a 9712 hsa-mir-7-1 Glioma 23373996 Regulation of Epidermal Growth Factor Receptor Signaling by plasmid-based MicroRNA-7 inhibits human malignant gliomas growth and metastasis in vivo 9713 hsa-mir-7-2 Glioma 23373996 Regulation of Epidermal Growth Factor Receptor Signaling by plasmid-based MicroRNA-7 inhibits human malignant gliomas growth and metastasis in vivo 9714 hsa-mir-7-3 Glioma 23373996 Regulation of Epidermal Growth Factor Receptor Signaling by plasmid-based MicroRNA-7 inhibits human malignant gliomas growth and metastasis in vivo 9715 hsa-mir-26b Breast Neoplasms 23374284 MiRNA-26b inhibits proliferation by targeting PTGS2 in breast cancer 9716 hsa-mir-132 Hepatitis B 23376496 serum;miR-132 may be a promising biochemical marker and may have therapeutic applications in HBV-related HCC 9717 hsa-mir-143 Glioblastoma 23376635 miR-143 inhibits glycolysis and depletes stemness of glioblastoma stem-like cells 9718 hsa-mir-141 Prostatic Neoplasms 23377530 serum;An elevated serum miR-141 level in patients with bone-metastatic prostate cancer is correlated with more bone lesions 9719 hsa-mir-106b Glioma 23377830 miR-106b facilitates glioma cell growth by promoting cell cycle progression through the negative regulation of RBL2 9720 hsa-mir-100 Carcinoma, Renal Cell 23378187 miR-100 overexpression strongly associates with advanced tumor progression and unfavorable clinical outcome of patients with RCC 9721 hsa-mir-126 Carcinoma, Hepatocellular 23378255 down-regulation of miR-126 plays an important role in HCC metastasis, and suggest a potential application of miR-126 in prognosis prediction and HCC treatment 9722 hsa-mir-16-1 Colorectal Neoplasms 23380758 microRNA-16 represses colorectal cancer cell growth in?vitro by regulating the p53/survivin signaling pathway 9723 hsa-mir-16-2 Colorectal Neoplasms 23380758 microRNA-16 represses colorectal cancer cell growth in?vitro by regulating the p53/survivin signaling pathway 9724 hsa-mir-200a Stomach Neoplasms 23381389 Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/beta-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma 9725 hsa-mir-195 Glioma 23383003 MicroRNA-195 Inhibits the Proliferation of Human Glioma Cells by Directly Targeting Cyclin D1 and Cyclin E1 9726 hsa-mir-30a Glioma 23383034 MiR-30a-5p Antisense Oligonucleotide Suppresses Glioma Cell Growth by Targeting SEPT7 9727 hsa-mir-182 Prostatic Neoplasms 23383207 MicroRNA-182-5p Promotes Cell Invasion and Proliferation by Down Regulating FOXF2, RECK and MTSS1 Genes in Human Prostate Cancer 9728 hsa-mir-9-1 Stomach Neoplasms 23383271 microRNA-9 Suppresses the Proliferation, Invasion and Metastasis of Gastric Cancer Cells through Targeting Cyclin D1 and Ets1 9729 hsa-mir-122 Hepatitis C 23383654 circulating;Sensitive detection of hepatocellular injury in chronic hepatitis C patients with circulating hepatocyte-derived microRNA-122 9730 hsa-mir-143 Prostatic Neoplasms 23383988 Up-regulated microRNA-143 in cancer stem cells differentiation promotes prostate cancer cells metastasis by modulating FNDC3B expression 9731 hsa-mir-7-1 Breast Neoplasms 23384942 miR-7 Suppresses Brain Metastasis of Breast Cancer Stem-Like Cells By Modulating KLF4 9732 hsa-mir-7-2 Breast Neoplasms 23384942 miR-7 Suppresses Brain Metastasis of Breast Cancer Stem-Like Cells By Modulating KLF4 9733 hsa-mir-7-3 Breast Neoplasms 23384942 miR-7 Suppresses Brain Metastasis of Breast Cancer Stem-Like Cells By Modulating KLF4 9734 hsa-mir-126 Vascular Diseases 23386708 plasma;Aspirin treatment hampers the use of plasma microRNA-126 as a biomarker for the progression of vascular disease 9735 hsa-mir-138-1 Ovarian Neoplasms 23389731 MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1a 9736 hsa-mir-138-2 Ovarian Neoplasms 23389731 MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1a 9737 hsa-mir-26a-1 Carcinoma, Hepatocellular 23389848 MicroRNA-26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting IL-6-Stat3 pathway 9738 hsa-mir-26a-2 Carcinoma, Hepatocellular 23389848 MicroRNA-26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting IL-6-Stat3 pathway 9739 hsa-mir-30a Breast Neoplasms 23389917 plasma; plasma miRNA-30a decreased in patients with BC and has great potential to use as novel biomarkers for BC diagnosis 9740 hsa-mir-200b Prostatic Neoplasms 23389960 Down-regulation of miR-200b-3p by low p73 contributes to the androgen-independence of prostate cancer cells 9741 hsa-mir-20a Hepatitis C 23390075 circulating;The circulating miR-20a may serve as a potential for predictive biomarker in HCV mediated fibrosis 9742 hsa-mir-145 Glioma 23390502 MicroRNA-145 Is Downregulated in Glial Tumors and Regulates Glioma Cell Migration by Targeting Connective Tissue Growth Factor 9743 hsa-mir-150 Leukemia, Myeloid, Acute 23391324 plasma;Circulating miR-150 and miR-342 in plasma are novel potential biomarkers for acute myeloid leukemia 9744 hsa-mir-342 Leukemia, Myeloid, Acute 23391324 plasma;Circulating miR-150 and miR-342 in plasma are novel potential biomarkers for acute myeloid leukemia 9745 hsa-mir-198 Carcinoma, Hepatocellular 23391410 Control of mitogenic and motogenic pathways by miR-198, diminishing hepatoma cell growth and migration 9746 hsa-mir-17 Glioblastoma 23391506 Stress Response of Glioblastoma Cells Mediated by miR-17-5p Targeting PTEN and the Passenger Strand miR-17-3p Targeting MDM2 9747 hsa-mir-145 Urinary Bladder Neoplasms 23392170 socs7, a target gene of microRNA-145, regulates interferon-alpha induction through STAT3 nuclear translocation in bladder cancer cells 9748 hsa-mir-130b Endometrial Neoplasms 23392577 miR-130b is an EMT-related microRNA that targets DICER1 for aggression in endometrial cancer 9749 hsa-mir-181a-1 Leukemia 23393335 MicroRNA 181a Influences the Expression of HMGB1 and CD4 in Acute Leukemias 9750 hsa-mir-181a-2 Leukemia 23393335 MicroRNA 181a Influences the Expression of HMGB1 and CD4 in Acute Leukemias 9751 hsa-mir-367 Colorectal Neoplasms 23393343 the functional variant (rs1044129) in the miR-367 binding site of RYR3 may be a potential marker for prognosis in patients following curative surgery for CRC 9752 hsa-mir-130a Colorectal Neoplasms 23393589 The Oncogenic Role of microRNA-130a/301a/454 in Human Colorectal Cancer via Targeting Smad4 Expression 9753 hsa-mir-301a Colorectal Neoplasms 23393589 The Oncogenic Role of microRNA-130a/301a/454 in Human Colorectal Cancer via Targeting Smad4 Expression 9754 hsa-mir-454 Colorectal Neoplasms 23393589 The Oncogenic Role of microRNA-130a/301a/454 in Human Colorectal Cancer via Targeting Smad4 Expression 9755 hsa-mir-200c Ovarian Neoplasms 23394580 a model for the combined regulatory activity of miR-200c and HuR on TUBB3 expression in ovarian cancer 9756 hsa-mir-126 Breast Neoplasms 23396050 miR-126 and miR-126(*) repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis 9757 hsa-mir-17 Ovarian Neoplasms 23396109 Downregulation of miR-17~92 Expression Increase Paclitaxel Sensitivity in Human Ovarian Carcinoma SKOV3-TR30 Cells via BIM Instead of PTEN 9758 hsa-mir-92a-1 Ovarian Neoplasms 23396109 Downregulation of miR-17~92 Expression Increase Paclitaxel Sensitivity in Human Ovarian Carcinoma SKOV3-TR30 Cells via BIM Instead of PTEN 9759 hsa-mir-92a-2 Ovarian Neoplasms 23396109 Downregulation of miR-17~92 Expression Increase Paclitaxel Sensitivity in Human Ovarian Carcinoma SKOV3-TR30 Cells via BIM Instead of PTEN 9760 hsa-mir-153-1 Glioblastoma 23397238 reactivation of miR-153 expression suggests novel therapeutic strategies for GBM-SCs 9761 hsa-mir-153-2 Glioblastoma 23397238 reactivation of miR-153 expression suggests novel therapeutic strategies for GBM-SCs 9762 hsa-mir-142 Colorectal Neoplasms 23397547 Downregulation of anti-oncomirs miR-143/145 cluster occurs before APC gene aberration in the development of colorectal tumors 9763 hsa-mir-145 Colorectal Neoplasms 23397547 Downregulation of anti-oncomirs miR-143/145 cluster occurs before APC gene aberration in the development of colorectal tumors 9764 hsa-mir-132 Breast Neoplasms 23399321 MicroRNA-132 is frequently down-regulated in ductal carcinoma in situ (DCIS) of breast and acts as a tumor suppressor by inhibiting cell proliferation 9765 hsa-mir-224 Inflammatory Bowel Diseases 23399735 MicroRNA-224 Negatively Regulates p21 Expression During Late Neoplastic Progression in Inflammatory Bowel Disease 9766 hsa-mir-137 Neuroblastoma 23400681 miR-137 directly targets KDM1A mRNA in neuroblastoma cells, and activates cell properties consistent with tumor suppression 9767 hsa-mir-221 Melanoma 23400877 The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway 9768 hsa-mir-222 Melanoma 23400877 The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway 9769 hsa-mir-29a Neoplasms 23401122 miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer 9770 hsa-mir-140 Carcinoma, Hepatocellular 23401231 MicroRNA-140-5p suppresses tumor growth and metastasis by targeting TGFBR1 and FGF9 in hepatocellular carcinoma 9771 hsa-mir-129-2 Carcinoma, Hepatocellular 23402613 Methylation-mediated repression of microRNA 129-2 enhances oncogenic SOX4 expression in HCC 9772 hsa-mir-124-1 Melanoma 23404119 miR-124a could function as a potent tumor suppressor in the development of uveal melanoma 9773 hsa-mir-124-2 Melanoma 23404119 miR-124a could function as a potent tumor suppressor in the development of uveal melanoma 9774 hsa-mir-124-3 Melanoma 23404119 miR-124a could function as a potent tumor suppressor in the development of uveal melanoma 9775 hsa-mir-145 Melanoma 23404256 miR-145 is an invasion suppressor in metastatic melanoma cells. Despite the fact that it remains unclear which genes or pathways are regulated by miR-145 in melanoma, miR-145 may serve as a useful therapeutic agent in melanoma when re-expressed in?situ 9776 hsa-mir-145 Prostatic Neoplasms 23404342 Wild-type p53 suppresses the epithelial-mesenchymal transition and stemness in PC-3 prostate cancer cells by modulating miR-145 9777 hsa-mir-7-1 Glioma 23404538 Poly(amido amine) is an ideal carrier of miR-7 for enhancing gene silencing effects on the EGFR pathway in U251 glioma cells 9778 hsa-mir-7-2 Glioma 23404538 Poly(amido amine) is an ideal carrier of miR-7 for enhancing gene silencing effects on the EGFR pathway in U251 glioma cells 9779 hsa-mir-7-3 Glioma 23404538 Poly(amido amine) is an ideal carrier of miR-7 for enhancing gene silencing effects on the EGFR pathway in U251 glioma cells 9780 hsa-mir-122 Hepatitis C 23405269 microRNA-122 Dependent Binding of Ago2 Protein to Hepatitis C Virus RNA Is Associated with Enhanced RNA Stability and Translation Stimulation 9781 hsa-mir-31 Urinary Bladder Neoplasms 23408039 Decreased expression of microRNA-31 associates with aggressive tumor progression and poor prognosis in patients with bladder cancer 9782 hsa-mir-342 Breast Neoplasms 23408138 miR-342 is associated with estrogen receptor-α expression and response to tamoxifen in breast cancer 9783 hsa-mir-99a Glioblastoma 23409016 Photofrin Based Photodynamic Therapy and miR-99a Transfection Inhibited FGFR3 and PI3K/Akt Signaling Mechanisms to Control Growth of Human Glioblastoma In Vitro and In Vivo 9784 hsa-mir-133a-1 Urinary Bladder Neoplasms 23410519 A Common microRNA Signature Consisting of miR-133a, miR-139-3p, and miR-142-3p Clusters Bladder Carcinoma in Situ With Normal Umbrella Cells 9785 hsa-mir-139 Urinary Bladder Neoplasms 23410519 A Common microRNA Signature Consisting of miR-133a, miR-139-3p, and miR-142-3p Clusters Bladder Carcinoma in Situ With Normal Umbrella Cells 9786 hsa-mir-142 Urinary Bladder Neoplasms 23410519 A Common microRNA Signature Consisting of miR-133a, miR-139-3p, and miR-142-3p Clusters Bladder Carcinoma in Situ With Normal Umbrella Cells 9787 hsa-mir-142 Lung Neoplasms 23410826 Serum: miR-142-3p is associated with early relapse in operable lung adenocarcinoma patients 9788 hsa-mir-142 Lung Neoplasms 23410826 Serum miR-142-3p is associated with early relapse in operable lung adenocarcinoma patients 9789 hsa-mir-151a Nasopharyngeal Neoplasms 23416081 A miR-151 binding site polymorphism in the 3'-untranslated region of the cyclin E1 gene associated with nasopharyngeal carcinoma 9790 hsa-mir-151b Nasopharyngeal Neoplasms 23416081 A miR-151 binding site polymorphism in the 3'-untranslated region of the cyclin E1 gene associated with nasopharyngeal carcinoma 9791 hsa-mir-30d Carcinoma, Renal Cell 23416459 MiR-30d induces apoptosis and is regulated by the Akt/FOXO pathway in renal cell carcinoma 9792 hsa-mir-106a Glioblastoma 23416698 MiR-106a is an independent prognostic marker in patients with glioblastoma 9793 hsa-mir-92b Glioma 23416699 miR-92b controls glioma proliferation and invasion through regulating Wnt/beta-catenin signaling via Nemo-like kinase 9794 hsa-mir-125b-1 Head and Neck Neoplasms 23416980 Loss of miR-125b-1 contributes to head and neck cancer development by dysregulating TACSTD2 and MAPK pathway 9795 hsa-mir-125b-2 Head and Neck Neoplasms 23416980 Loss of miR-125b-1 contributes to head and neck cancer development by dysregulating TACSTD2 and MAPK pathway 9796 hsa-mir-185 Prostatic Neoplasms 23417242 MicroRNA-185 suppresses proliferation, invasion, migration, and tumorigenicity of human prostate cancer cells through targeting androgen receptor 9797 hsa-mir-21 Liver Cirrhosis 23417858 Overexpression of microRNA-21 regulating PDCD4 during tumorigenesis of liver fluke-associated cholangiocarcinoma contributes to tumor growth and metastasis 9798 hsa-mir-17 Carcinoma, Hepatocellular 23418359 Mature MiR-17-5p and passenger miR-17-3p induce hepatocellular carcinoma by targeting PTEN, GalNT7, and vimentin in different signal pathways 9799 hsa-mir-24-1 Neoplasms 23418360 MicroRNA miR-24 Enhances Tumor Invasion and Metastasis by Targeting PTPN9 and PTPRF to Promote EGF Signaling 9800 hsa-mir-24-2 Neoplasms 23418360 MicroRNA miR-24 Enhances Tumor Invasion and Metastasis by Targeting PTPN9 and PTPRF to Promote EGF Signaling 9801 hsa-mir-320d-1 Sarcoma, Kaposi 23418466 Cellular MicroRNAs 498 and 320d Regulate Herpes Simplex Virus 1 Induction of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by Targeting RTA 9802 hsa-mir-320d-2 Sarcoma, Kaposi 23418466 Cellular MicroRNAs 498 and 320d Regulate Herpes Simplex Virus 1 Induction of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by Targeting RTA 9803 hsa-mir-498 Sarcoma, Kaposi 23418466 Cellular MicroRNAs 498 and 320d Regulate Herpes Simplex Virus 1 Induction of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by Targeting RTA 9804 hsa-mir-125a Breast Neoplasms 23420759 rs12976445 variant in the pri-miR-125a correlates with a lower level of hsa-miR-125a and ERBB2 overexpression in breast cancer patients 9805 hsa-mir-34c Stomach Neoplasms 23423488 Regulation of microtubule-associated protein tau (MAPT) by miR-34c-5p determines the chemosensitivity of gastric cancer to paclitaxel 9806 hsa-mir-181c Stomach Neoplasms 23425811 miR-181c expression level was significantly related to several clinicopathological features of gastric cancer 9807 hsa-mir-125b-1 Urinary Bladder Neoplasms 23425975 microRNA-125b inhibits cell migration and invasion by targeting matrix metallopeptidase 13 in bladder cancer 9808 hsa-mir-125b-2 Urinary Bladder Neoplasms 23425975 microRNA-125b inhibits cell migration and invasion by targeting matrix metallopeptidase 13 in bladder cancer 9809 hsa-mir-487b Lung Neoplasms 23426183 Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis 9810 hsa-mir-154 Prostatic Neoplasms 23428540 miR-154 inhibits prostate cancer cell proliferation by targeting CCND2 9811 hsa-mir-210 Osteosarcoma 23430441 miR-210 upregulation showed a strong correlation with tumor aggressive progression of pediatric osteosarcoma and could help prognostic screening of patients with this malignancy 9812 hsa-mir-570 Stomach Neoplasms 23430453 A miR-570 binding site polymorphism in the B7-H1 gene is associated with the risk of gastric adenocarcinoma 9813 hsa-mir-182 Breast Neoplasms 23430586 Expression and regulatory function of miRNA-182 in triple-negative breast cancer cells through its targeting of profilin 1 9814 hsa-mir-27a Pancreatic Neoplasms 23430754 blood;Combined serum CA19-9 and miR-27a-3p in peripheral blood mononuclear cells to diagnose pancreatic cancer 9815 hsa-mir-181b-1 Glioma 23431408 MiRNA-181b suppresses IGF-1R and functions as a tumor suppressor gene in gliomas 9816 hsa-mir-181b-2 Glioma 23431408 MiRNA-181b suppresses IGF-1R and functions as a tumor suppressor gene in gliomas 9817 hsa-mir-196a-2 Vitiligo 23433405 A Single Nucleotide Polymorphism of miR-196a-2 and Vitiligo: An Association Study and Functional Analysis in a Han Chinese Population 9818 hsa-mir-25 Colorectal Neoplasms 23435373 MicroRNA-25 functions as a potential tumor suppressor in colon cancer by targeting Smad7 9819 hsa-mir-146a Stomach Neoplasms 23435376 MicroRNA-146a acts as a metastasis suppressor in gastric cancer by targeting WASF2 9820 hsa-mir-29b-1 Alzheimer Disease 23435408 blood;Expression of the Transcription Factor Sp1 and its Regulatory hsa-miR-29b in Peripheral Blood Mononuclear Cells from Patients with Alzheimer's Disease 9821 hsa-mir-29b-2 Alzheimer Disease 23435408 blood;Expression of the Transcription Factor Sp1 and its Regulatory hsa-miR-29b in Peripheral Blood Mononuclear Cells from Patients with Alzheimer's Disease 9822 hsa-mir-155 Laryngeal Neoplasms 23437123 Overexpression of miR -155 Promotes Proliferation and Invasion of Human Laryngeal Squamous Cell Carcinoma via Targeting SOCS1 and STAT3 9823 hsa-mir-125b-1 Neoplasms 23437196 Forced expression of HER2 and HER3 rescued miR-199a- and miR-125b-inhibiting angiogenesis responses and Akt/p70S6K1/HIF-1α pathway. 9824 hsa-mir-125b-2 Neoplasms 23437196 Forced expression of HER2 and HER3 rescued miR-199a- and miR-125b-inhibiting angiogenesis responses and Akt/p70S6K1/HIF-1α pathway. 9825 hsa-mir-199a-1 Neoplasms 23437196 Forced expression of HER2 and HER3 rescued miR-199a- and miR-125b-inhibiting angiogenesis responses and Akt/p70S6K1/HIF-1α pathway. 9826 hsa-mir-199a-2 Neoplasms 23437196 Forced expression of HER2 and HER3 rescued miR-199a- and miR-125b-inhibiting angiogenesis responses and Akt/p70S6K1/HIF-1α pathway. 9827 hsa-mir-126 Melanoma 23437250 miR-126&126* Restored Expressions Play a Tumor Suppressor Role by Directly Regulating ADAM9 and MMP7 in Melanoma 9828 hsa-mir-18a Colorectal Neoplasms 23437304 MicroRNA-18a Attenuates DNA Damage Repair through Suppressing the Expression of Ataxia Telangiectasia Mutated in Colorectal Cancer 9829 hsa-mir-27a Ovarian Neoplasms 23438830 Oncogenic MicroRNA-27a is a Target for Genistein in Ovarian Cancer Cells 9830 hsa-mir-135a-1 Neoplasms 23438844 MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells 9831 hsa-mir-135a-2 Neoplasms 23438844 MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells 9832 hsa-mir-138-1 Neoplasms 23438844 MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells 9833 hsa-mir-138-2 Neoplasms 23438844 MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells 9834 hsa-mir-200a Colorectal Neoplasms 23441132 Down-Regulation of the miRNA-200 Family at the Invasive Front of Colorectal Cancers with Degraded Basement Membrane Indicates EMT Is Involved in Cancer Progression 9835 hsa-mir-200b Colorectal Neoplasms 23441132 Down-Regulation of the miRNA-200 Family at the Invasive Front of Colorectal Cancers with Degraded Basement Membrane Indicates EMT Is Involved in Cancer Progression 9836 hsa-mir-200c Colorectal Neoplasms 23441132 Down-Regulation of the miRNA-200 Family at the Invasive Front of Colorectal Cancers with Degraded Basement Membrane Indicates EMT Is Involved in Cancer Progression 9837 hsa-mir-145 Carcinoma, Renal Cell 23441135 MicroRNA-145 Targets the Metalloprotease ADAM17 and Is Suppressed in Renal Cell Carcinoma Patients 9838 hsa-mir-21 Carcinoma, Hepatocellular 23442323 Thyroid hormone regulation of miR-21 enhances migration and invasion of hepatoma 9839 hsa-mir-29c Stomach Neoplasms 23442884 MiR-29c is downregulated in gastric carcinomas and regulates cell proliferation by targeting RCC2 9840 hsa-mir-218-1 Uterine Cervical Neoplasms 23443110 MiR-218 Impairs Tumor Growth and Increases Chemo-Sensitivity to Cisplatin in Cervical Cancer 9841 hsa-mir-218-2 Uterine Cervical Neoplasms 23443110 MiR-218 Impairs Tumor Growth and Increases Chemo-Sensitivity to Cisplatin in Cervical Cancer 9842 hsa-mir-30a Breast Neoplasms 23445407 MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells 9843 hsa-mir-138-1 Head and Neck Neoplasms 23445815 Role of microRNA-138 as a Potential Tumor Suppressor in Head and Neck Squamous Cell Carcinoma 9844 hsa-mir-138-2 Head and Neck Neoplasms 23445815 Role of microRNA-138 as a Potential Tumor Suppressor in Head and Neck Squamous Cell Carcinoma 9845 hsa-mir-21 Multiple Myeloma 23446999 Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth 9846 hsa-mir-203 Breast Neoplasms 23447531 Signaling between TGF-beta and Transcription factor SNAI2 Represses Expression of microRNA miR-203 to Promote Epithelial-Mesenchymal Transition and Tumor Metastasis 9847 hsa-mir-378a Cardiomegaly 23447532 A cardiac enriched microRNA, miR-378 blocks cardiac hypertrophy by targeting Ras-signaling 9848 hsa-mir-210 Carcinoma, Renal Cell 23449350 miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis 9849 hsa-mir-27a Hepatitis C 23449803 MicroRNA-27a regulates lipid metabolism and inhibits hepatitis C virus replication in human hepatoma cells 9850 hsa-mir-23a Endometriosis 23450049 MicroRNA23a and MicroRNA23b Deregulation Derepresses SF-1 and Upregulates Estrogen Signaling in Ovarian Endometriosis 9851 hsa-mir-23b Endometriosis 23450049 MicroRNA23a and MicroRNA23b Deregulation Derepresses SF-1 and Upregulates Estrogen Signaling in Ovarian Endometriosis 9852 hsa-mir-30a Lupus Erythematosus, Systemic 23450709 MicroRNA-30a promotes B cell hyperactivity in patient with SLE by direct interaction with LYN 9853 hsa-mir-195 Tongue Neoplasms 23451060 Prognostic Implications of MicoRNA miR-195 Expression in Human Tongue Squamous Cell Carcinoma 9854 hsa-mir-146a Thyroid Neoplasms 23451063 Association between the rs2910164 Polymorphism in Pre-Mir-146a Sequence and Thyroid Carcinogenesis 9855 hsa-mir-497 Uterine Cervical Neoplasms 23453369 MicroRNA-497 is a potential prognostic marker in human cervical cancer and functions as a tumor suppressor by targeting the insulin-like growth factor 1 receptor 9856 hsa-mir-218-1 Carcinoma, Renal Cell 23454155 microRNA-218 inhibits cell migration and invasion in renal cell carcinoma through targeting caveolin-2 involved in focal adhesion pathway 9857 hsa-mir-218-2 Carcinoma, Renal Cell 23454155 microRNA-218 inhibits cell migration and invasion in renal cell carcinoma through targeting caveolin-2 involved in focal adhesion pathway 9858 hsa-mir-335 Prostatic Neoplasms 23456549 Our data demonstrated for the first time the inhibitory effect of miR-335 on cell proliferation and invasion for PCa cells 9859 hsa-mir-146a Thyroid Neoplasms 23457043 MicroRNA-146a targets PRKCE to modulate papillary thyroid tumor development 9860 hsa-mir-22 Carcinoma, Hepatocellular 23766411 miR-22 is downregulated in HCC and its expression is associated with the differentiation, metastasis and prognosis of the carcinoma. Ezrin is a potential regulatory protein of miR-22. 9861 hsa-mir-30a Ovarian Neoplasms 23766361 The clear cell histotype is characterized by a five-fold (log scale) higher expression of miR-30a and miR-30a*, while mucinous histotype has five-fold (log scale) higher levels of miR-192/194. Furthermore a mucinous-specific regulatory loop involving miR-192/194 cluster and a differential regulation of E2F3 in clear cell histotype were identified. 9862 hsa-mir-192 Ovarian Neoplasms 23766361 The clear cell histotype is characterized by a five-fold (log scale) higher expression of miR-30a and miR-30a*, while mucinous histotype has five-fold (log scale) higher levels of miR-192/194. Furthermore a mucinous-specific regulatory loop involving miR-192/194 cluster and a differential regulation of E2F3 in clear cell histotype were identified. 9863 hsa-mir-194-1 Ovarian Neoplasms 23766361 The clear cell histotype is characterized by a five-fold (log scale) higher expression of miR-30a and miR-30a*, while mucinous histotype has five-fold (log scale) higher levels of miR-192/194. Furthermore a mucinous-specific regulatory loop involving miR-192/194 cluster and a differential regulation of E2F3 in clear cell histotype were identified. 9864 hsa-mir-194-2 Ovarian Neoplasms 23766361 The clear cell histotype is characterized by a five-fold (log scale) higher expression of miR-30a and miR-30a*, while mucinous histotype has five-fold (log scale) higher levels of miR-192/194. Furthermore a mucinous-specific regulatory loop involving miR-192/194 cluster and a differential regulation of E2F3 in clear cell histotype were identified. 9865 hsa-mir-18b Nasopharyngeal Neoplasms 23764853 Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma. 9866 hsa-mir-199a-1 Muscular Dystrophy, Duchenne 23764775 MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation. 9867 hsa-mir-199a-2 Muscular Dystrophy, Duchenne 23764775 MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation. 9868 hsa-mir-155 Leukemia-Lymphoma, Adult T-Cell 23762762 Cellular MicroRNA miR-155 has Important Roles in Leukemogenesis by Human T-Cell Leukemia Virus Type 1 Infection. 9869 hsa-mir-149 Carcinoma, Non-Small-Cell Lung 23762558 miR-149 Inhibits Non-Small-Cell Lung Cancer Cells EMT by Targeting FOXM1. 9870 hsa-mir-127 Carcinoma, Hepatocellular 23762330 A Feedback Inhibition between miRNA-127 and TGFbeta/c-Jun Cascade in HCC Cell Migration via MMP13. 9871 hsa-mir-99a Diabetes Mellitus, Type 2 23762265 Insulin Promotes Glucose Consumption via Regulation of miR-99a/mTOR/PKM2 Pathway. 9872 hsa-mir-15a Esophageal Neoplasms 23761828 upregulated 9873 hsa-mir-28 Esophageal Neoplasms 23761828 miR-28-3p: upregulated 9874 hsa-mir-31 Esophageal Neoplasms 23761828 upregulated 9875 hsa-mir-99b Esophageal Neoplasms 23761828 upregulated 9876 hsa-mir-101-1 Esophageal Neoplasms 23761828 upregulated 9877 hsa-mir-101-2 Esophageal Neoplasms 23761828 upregulated 9878 hsa-mir-130a Esophageal Neoplasms 23761828 upregulated 9879 hsa-mir-130b Esophageal Neoplasms 23761828 upregulated 9880 hsa-mir-143 Esophageal Neoplasms 23761828 upregulated 9881 hsa-mir-196b Esophageal Neoplasms 23761828 upregulated 9882 hsa-mir-200a Esophageal Neoplasms 23761828 upregulated 9883 hsa-mir-210 Esophageal Neoplasms 23761828 upregulated 9884 hsa-mir-452 Esophageal Neoplasms 23761828 upregulated 9885 hsa-mir-27a Esophageal Neoplasms 23761828 upregulated 9886 hsa-mir-223 Esophageal Neoplasms 23761828 downregulated 9887 hsa-mir-454 Esophageal Neoplasms 23761828 downregulated 9888 hsa-mir-486 Esophageal Neoplasms 23761828 downregulated 9889 hsa-mir-574 Esophageal Neoplasms 23761828 miR-574-3p:downregulated 9890 hsa-mir-126 Esophageal Neoplasms 23761828 downregulated 9891 hsa-mir-30b Esophageal Neoplasms 23761828 downregulated 9892 hsa-mir-1-1 Lung Neoplasms 23761296 Sustainable downregulation in the lung tissues in lung carcinogenesis induced by urethane. 9893 hsa-mir-1-2 Lung Neoplasms 23761296 Sustainable downregulation in the lung tissues in lung carcinogenesis induced by urethane. 9894 hsa-mir-124-1 Glioma 23761023 miR-124 radiosensitizes human glioma cells by targeting CDK4. 9895 hsa-mir-124-2 Glioma 23761023 miR-124 radiosensitizes human glioma cells by targeting CDK4. 9896 hsa-mir-200a Carcinoma, Hepatocellular 23760980 MicroRNA-200a/b influenced the therapeutic effects of curcumin in hepatocellular carcinoma (HCC) cells. 9897 hsa-mir-200b Carcinoma, Hepatocellular 23760980 MicroRNA-200a/b influenced the therapeutic effects of curcumin in hepatocellular carcinoma (HCC) cells. 9898 hsa-mir-199a-1 HCMV Infection 23760629 MiR-199a-5p promotes migration and tube formation of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and eNOS. 9899 hsa-mir-199a-2 HCMV Infection 23760629 MiR-199a-5p promotes migration and tube formation of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and eNOS. 9900 hsa-mir-195 Breast Neoplasms 23760062 Upregulation of miR-195 increases the sensitivity of breast cancer cells to Adriamycin treatment through inhibition of Raf-1. 9901 hsa-mir-17 Polycystic Kidney Diseases 23759744 miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. 9902 hsa-mir-18a Polycystic Kidney Diseases 23759744 miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. 9903 hsa-mir-19a Polycystic Kidney Diseases 23759744 miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. 9904 hsa-mir-19b-1 Polycystic Kidney Diseases 23759744 miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. 9905 hsa-mir-20a Polycystic Kidney Diseases 23759744 miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. 9906 hsa-mir-92a-1 Polycystic Kidney Diseases 23759744 miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. 9907 hsa-mir-200a Neoplasms 23759590 KDM5B histone demethylase controls epithelial-mesenchymal transition of cancer cells by regulating the expression of the microRNA-200 family. 9908 hsa-mir-200b Neoplasms 23759590 KDM5B histone demethylase controls epithelial-mesenchymal transition of cancer cells by regulating the expression of the microRNA-200 family. 9909 hsa-mir-200c Neoplasms 23759590 KDM5B histone demethylase controls epithelial-mesenchymal transition of cancer cells by regulating the expression of the microRNA-200 family. 9910 hsa-mir-125b-1 Multiple Myeloma 23759586 Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression. 9911 hsa-mir-125b-2 Multiple Myeloma 23759586 Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression. 9912 hsa-mir-181a-1 Breast Neoplasms 23759567 MicroRNA-181a/b: Novel biomarkers to stratify breast cancer patients for PARPi treatment. 9913 hsa-mir-181a-2 Breast Neoplasms 23759567 MicroRNA-181a/b: Novel biomarkers to stratify breast cancer patients for PARPi treatment. 9914 hsa-mir-181b-1 Breast Neoplasms 23759567 MicroRNA-181a/b: Novel biomarkers to stratify breast cancer patients for PARPi treatment. 9915 hsa-mir-181b-2 Breast Neoplasms 23759567 MicroRNA-181a/b: Novel biomarkers to stratify breast cancer patients for PARPi treatment. 9916 hsa-mir-30a Carcinoma, Non-Small-Cell Lung 23758992 BCL11A overexpression predicts survival and relapse in non-small cell lung cancer and is modulated by microRNA-30a and gene amplification. 9917 hsa-mir-193a Colorectal Neoplasms 23758639 Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer. 9918 hsa-mir-23a Colorectal Neoplasms 23758639 Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer. 9919 hsa-mir-338 Colorectal Neoplasms 23758639 Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer. 9920 hsa-mir-223 Barrett Esophagus 23757351 MicroRNA 223 is Up-regulated in the Multistep Progression of Barrett's Esophagus and Modulates Sensitivity to Chemotherapy by Targeting PARP1. 9921 hsa-mir-221 Obesity 23756832 Human adipose microRNA-221 is upregulated in obesity and affects fat metabolism downstream of leptin and TNF-alpha 9922 hsa-mir-483 Adrenocortical Carcinoma 23756429 Serum miR-483-5p and miR-195 are predictive of recurrence risk in adrenocortical cancer patients. 9923 hsa-mir-195 Adrenocortical Carcinoma 23756429 Serum miR-483-5p and miR-195 are predictive of recurrence risk in adrenocortical cancer patients. 9924 hsa-mir-146a Sepsis 23756365 Morphine induced exacerbation of sepsis is mediated by tempering endotoxin tolerance through modulation of miR-146a. 9925 hsa-mir-133a-1 Osteosarcoma 23756231 microRNA-133a, downregulated in osteosarcoma, suppresses proliferation and promotes apoptosis by targeting Bcl-xL and Mcl-1. 9926 hsa-mir-133a-2 Osteosarcoma 23756231 microRNA-133a, downregulated in osteosarcoma, suppresses proliferation and promotes apoptosis by targeting Bcl-xL and Mcl-1. 9927 hsa-mir-21 Carcinoma, Non-Small-Cell Lung 23756108 Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed 9928 hsa-mir-30d Carcinoma, Non-Small-Cell Lung 23756108 Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed 9929 hsa-mir-451a Carcinoma, Non-Small-Cell Lung 23756108 Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed 9930 hsa-mir-451b Carcinoma, Non-Small-Cell Lung 23756108 Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed 9931 hsa-mir-10a Carcinoma, Non-Small-Cell Lung 23756108 Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed 9932 hsa-mir-30e Carcinoma, Non-Small-Cell Lung 23756108 Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed 9933 hsa-mir-126 Carcinoma, Non-Small-Cell Lung 23756108 Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed 9934 hsa-mir-145 Carcinoma, Non-Small-Cell Lung 23756108 Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed 9935 hsa-mir-124a-2 Carcinoma, Renal Cell 23755536 The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue 9936 hsa-mir-124a-3 Carcinoma, Renal Cell 23755536 The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue 9937 hsa-mir-9-1 Carcinoma, Renal Cell 23755536 The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue 9938 hsa-mir-9-3 Carcinoma, Renal Cell 23755536 The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue 9939 hsa-mir-34b Carcinoma, Renal Cell 23755536 The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue 9940 hsa-mir-34c Carcinoma, Renal Cell 23755536 The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue 9941 hsa-mir-129-2 Carcinoma, Renal Cell 23755536 The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue 9942 hsa-mir-124-1 Cerebral Ischemia 23754622 MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation. 9943 hsa-mir-124-2 Cerebral Ischemia 23754622 MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation. 9944 hsa-mir-200c Carcinoma, Renal Cell 23754305 microRNA-200c modulates the epithelial-to-mesenchymal transition in human renal cell carcinoma metastasis. 9945 hsa-mir-708 Glioblastoma 23754151 miR-708 acts as a tumor suppressor in human glioblastoma cells. 9946 hsa-mir-21 Pancreatic Neoplasms 23752880 Endoscopically Acquired Pancreatic Cyst Fluid MicroRNA 21 and 221 Are Associated With Invasive Cancer. 9947 hsa-mir-221 Pancreatic Neoplasms 23752880 Endoscopically Acquired Pancreatic Cyst Fluid MicroRNA 21 and 221 Are Associated With Invasive Cancer. 9948 hsa-mir-142 SIV Infection 23752207 Up-regulation of microRNA-142 in simian immunodeficiency virus encephalitis leads to repression of sirtuin1. 9949 hsa-mir-140 Breast Neoplasms 23752191 Downregulation of miR-140 promotes cancer stem cell formation in basal-like early stage breast cancer. 9950 hsa-mir-96 Pancreatic Neoplasms 23752186 EVI1 oncogene promotes KRAS pathway through suppression of microRNA-96 in pancreatic carcinogenesis. 9951 hsa-mir-27a Breast Neoplasms 23752185 miR-27a regulates endothelial differentiation of breast cancer stem like cells. 9952 hsa-mir-206 Stomach Neoplasms 23751352 Downregulation of microRNA-206 is a potent prognostic marker for patients with gastric cancer. 9953 hsa-mir-26a-1 Breast Neoplasms 23750239 MiR-26a Inhibits Proliferation and Migration of Breast Cancer through Repression of MCL-1. 9954 hsa-mir-26a-2 Breast Neoplasms 23750239 MiR-26a Inhibits Proliferation and Migration of Breast Cancer through Repression of MCL-1. 9955 hsa-mir-155 Leukemia, Lymphocytic, Chronic, B-Cell 23750211 Signal Transducer and Activator of Transcription-3 Induces MicroRNA-155 Expression in Chronic Lymphocytic Leukemia. 9956 hsa-mir-21 Uterine Cervical Neoplasms 23749909 altered expression 9957 hsa-mir-27a Uterine Cervical Neoplasms 23749909 altered expression 9958 hsa-mir-34a Uterine Cervical Neoplasms 23749909 altered expression 9959 hsa-mir-146a Uterine Cervical Neoplasms 23749909 altered expression 9960 hsa-mir-155 Uterine Cervical Neoplasms 23749909 altered expression 9961 hsa-mir-196a-1 Uterine Cervical Neoplasms 23749909 altered expression 9962 hsa-mir-196a-2 Uterine Cervical Neoplasms 23749909 altered expression 9963 hsa-mir-203 Uterine Cervical Neoplasms 23749909 altered expression 9964 hsa-mir-221 Uterine Cervical Neoplasms 23749909 altered expression 9965 hsa-mir-17 Breast Neoplasms 23748853 Deregulated Serum Concentrations of Circulating Cell-Free MicroRNAs miR-17, miR-34a, miR-155, and miR-373 in Human Breast Cancer Development and Progression. 9966 hsa-mir-34a Breast Neoplasms 23748853 Deregulated Serum Concentrations of Circulating Cell-Free MicroRNAs miR-17, miR-34a, miR-155, and miR-373 in Human Breast Cancer Development and Progression. 9967 hsa-mir-155 Breast Neoplasms 23748853 Deregulated Serum Concentrations of Circulating Cell-Free MicroRNAs miR-17, miR-34a, miR-155, and miR-373 in Human Breast Cancer Development and Progression. 9968 hsa-mir-373 Breast Neoplasms 23748853 Deregulated Serum Concentrations of Circulating Cell-Free MicroRNAs miR-17, miR-34a, miR-155, and miR-373 in Human Breast Cancer Development and Progression. 9969 hsa-mir-1-1 Myocardial Infarction 23747779 Circulating miR-1, miR-208a, and miR-133a continuously rose during the first 4 h after induction of AMI. 9970 hsa-mir-1-2 Myocardial Infarction 23747779 Circulating miR-1, miR-208a, and miR-133a continuously rose during the first 4 h after induction of AMI. 9971 hsa-mir-133a-1 Myocardial Infarction 23747779 Circulating miR-1, miR-208a, and miR-133a continuously rose during the first 4 h after induction of AMI. 9972 hsa-mir-133a-2 Myocardial Infarction 23747779 Circulating miR-1, miR-208a, and miR-133a continuously rose during the first 4 h after induction of AMI. 9973 hsa-mir-208a Myocardial Infarction 23747779 Circulating miR-1, miR-208a, and miR-133a continuously rose during the first 4 h after induction of AMI. 9974 hsa-mir-150 Lung Neoplasms 23747308 miR-150 promotes the proliferation of lung cancer cells by targeting P53. 9975 hsa-mir-145 Stroke 23745809 antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo. 9976 hsa-mir-497 Stroke 23745809 antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo. 9977 hsa-mir-181a-1 Stroke 23745809 antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo. 9978 hsa-mir-181a-2 Stroke 23745809 antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo. 9979 hsa-mir-1-1 Stroke 23745809 antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo. 9980 hsa-mir-1-2 Stroke 23745809 antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo. 9981 hsa-let-7f-1 Stroke 23745809 antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo. 9982 hsa-let-7f-2 Stroke 23745809 antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo. 9983 hsa-mir-126 Colonic Neoplasms 23744532 Expression of miR-126 suppresses migration and invasion of colon cancer cells by targeting CXCR4. 9984 hsa-mir-129-1 Colorectal Neoplasms 23744359 miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer. 9985 hsa-mir-129-2 Colorectal Neoplasms 23744359 miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer. 9986 hsa-mir-200a Endometrial Neoplasms 23743934 ZEB1 overexpression associated with E-cadherin and microRNA-200 downregulation is characteristic of undifferentiated endometrial carcinoma. 9987 hsa-mir-200b Endometrial Neoplasms 23743934 ZEB1 overexpression associated with E-cadherin and microRNA-200 downregulation is characteristic of undifferentiated endometrial carcinoma. 9988 hsa-mir-200c Endometrial Neoplasms 23743934 ZEB1 overexpression associated with E-cadherin and microRNA-200 downregulation is characteristic of undifferentiated endometrial carcinoma. 9989 hsa-mir-7-1 Uterine Cervical Neoplasms 23742934 MicroRNA-7 downregulates XIAP expression to suppress cell growth and promote apoptosis in cervical cancer cells. 9990 hsa-mir-7-2 Uterine Cervical Neoplasms 23742934 MicroRNA-7 downregulates XIAP expression to suppress cell growth and promote apoptosis in cervical cancer cells. 9991 hsa-mir-7-3 Uterine Cervical Neoplasms 23742934 MicroRNA-7 downregulates XIAP expression to suppress cell growth and promote apoptosis in cervical cancer cells. 9992 hsa-mir-199a-1 Carcinoma, Hepatocellular 23742776 Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression. 9993 hsa-mir-199a-2 Carcinoma, Hepatocellular 23742776 Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression. 9994 hsa-mir-96 Urinary Bladder Neoplasms 23741253 miR-96 regulates FOXO1-mediated cell apoptosis in bladder cancer. 9995 hsa-mir-224 Carcinoma, Hepatocellular 23741247 miR-224 functions as an onco-miRNA in hepatocellular carcinoma cells by activating AKT signaling. 9996 hsa-mir-181a-1 PRRSV Infection 23740977 MicroRNA-181 suppresses PRRSV infection by targeting its receptor CD163. 9997 hsa-mir-181a-2 PRRSV Infection 23740977 MicroRNA-181 suppresses PRRSV infection by targeting its receptor CD163. 9998 hsa-mir-181b-1 PRRSV Infection 23740977 MicroRNA-181 suppresses PRRSV infection by targeting its receptor CD163. 9999 hsa-mir-181b-2 PRRSV Infection 23740977 MicroRNA-181 suppresses PRRSV infection by targeting its receptor CD163. 10000 hsa-mir-181c PRRSV Infection 23740977 MicroRNA-181 suppresses PRRSV infection by targeting its receptor CD163. 10001 hsa-mir-451a Carcinoma, Hepatocellular 23740840 miR-451 Inhibits Cell Proliferation in Human Hepatocellular Carcinoma through Direct Suppression of IKK-beta 10002 hsa-mir-181a-1 Osteosarcoma 23740615 MicroRNA 181a improves proliferation and invasion, suppresses apoptosis of osteosarcoma cell. 10003 hsa-mir-181a-2 Osteosarcoma 23740615 MicroRNA 181a improves proliferation and invasion, suppresses apoptosis of osteosarcoma cell. 10004 hsa-mir-26b Heart Failure 23736534 Changed circulating miRNA-26b-5p, miRNA-145-5p, miRNA-92a-3p, miRNA-30e-5p, and miRNA-29a-3p 10005 hsa-mir-145 Heart Failure 23736534 Changed circulating miRNA-26b-5p, miRNA-145-5p, miRNA-92a-3p, miRNA-30e-5p, and miRNA-29a-3p 10006 hsa-mir-92a-1 Heart Failure 23736534 Changed circulating miRNA-26b-5p, miRNA-145-5p, miRNA-92a-3p, miRNA-30e-5p, and miRNA-29a-3p 10007 hsa-mir-92a-2 Heart Failure 23736534 Changed circulating miRNA-26b-5p, miRNA-145-5p, miRNA-92a-3p, miRNA-30e-5p, and miRNA-29a-3p 10008 hsa-mir-30e Heart Failure 23736534 Changed circulating miRNA-26b-5p, miRNA-145-5p, miRNA-92a-3p, miRNA-30e-5p, and miRNA-29a-3p 10009 hsa-mir-29a Heart Failure 23736534 Changed circulating miRNA-26b-5p, miRNA-145-5p, miRNA-92a-3p, miRNA-30e-5p, and miRNA-29a-3p 10010 hsa-mir-485 Carcinoma, Non-Small-Cell Lung 23734217 hsa-mir-485 Prostatic Neoplasms Prostatic Neoplasms Cytotoxic treatment of DU-145 cells enhanced the release of PCS-miRNAs with the exception of miR-485-3p which was retained by surviving cells. 10011 hsa-mir-199a-1 Stomach Neoplasms 23733518 MiRNA-199a-3p: A Potential Circulating Diagnostic Biomarker for Early Gastric Cancer. 10012 hsa-mir-199a-2 Stomach Neoplasms 23733518 MiRNA-199a-3p: A Potential Circulating Diagnostic Biomarker for Early Gastric Cancer. 10013 hsa-mir-128-1 Glioma 23733246 MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells. 10014 hsa-mir-128-2 Glioma 23733246 MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells. 10015 hsa-mir-218-1 Pancreatic Neoplasms 23733161 The microRNA-218 and ROBO-1 signaling axis correlates with the lymphatic metastasis of pancreatic cancer. 10016 hsa-mir-218-2 Pancreatic Neoplasms 23733161 The microRNA-218 and ROBO-1 signaling axis correlates with the lymphatic metastasis of pancreatic cancer. 10017 hsa-mir-203 Pancreatic Neoplasms 23732815 miR-203 regulates the proliferation, apoptosis and cell cycle progression of pancreatic cancer cells by targeting Survivin. 10018 hsa-mir-143 Prostatic Neoplasms 23732700 MicroRNA-143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer. 10019 hsa-mir-21 Glioblastoma 23732394 Silencing of miR-21 by locked nucleic acid-lipid nanocapsule complexes sensitize human glioblastoma cells to radiation-induced cell death. 10020 hsa-mir-432 HPV Infection 23732000 We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines. 10021 hsa-mir-1286 HPV Infection 23732000 We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines. 10022 hsa-mir-641 HPV Infection 23732000 We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines. 10023 hsa-mir-1290 HPV Infection 23732000 We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines. 10024 hsa-mir-1287 HPV Infection 23732000 We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines. 10025 hsa-mir-95 HPV Infection 23732000 We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines. 10026 hsa-mir-503 Carcinoma, Endometrioid 23731275 MicroRNA-503 suppresses proliferation and cell cycle progression of endometrioid ndometrial cancer via negatively regulating cyclin D1. 10027 hsa-mir-370 Carcinoma, Hepatocellular 23728999 Perturbation of miR-370-LIN28A-NF-NJB regulatory circuit contributes to the development of hepatocellular carcinoma. 10028 hsa-mir-29c Carcinoma, Hepatocellular 23728341 MicroRNA-29c functions as a tumor suppressor by direct targeting oncogenic SIRT1 in hepatocellular carcinoma. 10029 hsa-mir-21 Fatty Liver, Non-Alcoholic 23727030 Serum levels of miRNAs, miR-21, miR-34a, miR-122, and miR-451 were higher in participants with NAFLD. The serum level of miR-122 was correlated with the severity of liver steatosis. 10030 hsa-mir-34a Fatty Liver, Non-Alcoholic 23727030 Serum levels of miRNAs, miR-21, miR-34a, miR-122, and miR-451 were higher in participants with NAFLD. The serum level of miR-122 was correlated with the severity of liver steatosis. 10031 hsa-mir-122 Fatty Liver, Non-Alcoholic 23727030 Serum levels of miRNAs, miR-21, miR-34a, miR-122, and miR-451 were higher in participants with NAFLD. The serum level of miR-122 was correlated with the severity of liver steatosis. 10032 hsa-mir-451 Fatty Liver, Non-Alcoholic 23727030 Serum levels of miRNAs, miR-21, miR-34a, miR-122, and miR-451 were higher in participants with NAFLD. The serum level of miR-122 was correlated with the severity of liver steatosis. 10033 hsa-mir-211 Head and Neck Neoplasms 23726841 miR-211 promotes the progression of head and neck carcinomas by targeting TGFbeta R2. 10034 hsa-mir-491 Carcinoma, Hepatocellular 23725476 MicroRNA-491 is involved in metastasis of hepatocellular carcinoma by inhibitions of matrix metalloproteinase and epithelial to mesenchymal transition. 10035 hsa-mir-184 Stomach Neoplasms 23724109 The miR-184 Binding-Site rs8126 T>C Polymorphism in TNFAIP2 Is Associated with Risk of Gastric Cancer. 10036 hsa-mir-122 Carcinoma, Hepatocellular 23723713 Circulating microRNA-122a as a diagnostic marker for hepatocellular carcinoma. 10037 hsa-mir-133a-1 Colorectal Neoplasms 23723074 MiR-133a activates the p53/p21 pathway and functions as a tumor suppressor in colorectal cancer by repressing RFFL. 10038 hsa-mir-133a-2 Colorectal Neoplasms 23723074 MiR-133a activates the p53/p21 pathway and functions as a tumor suppressor in colorectal cancer by repressing RFFL. 10039 hsa-mir-370 Stomach Neoplasms 23721824 Upregulation of miR-370 contributes to the progression of gastric carcinoma via suppression of FOXO1. 10040 hsa-mir-218-2 Thyroid Neoplasms 23720784 Down-regulation of miR-218-2 and its host gene SLIT3 cooperate to promote invasion and progression of thyroid cancer. 10041 hsa-mir-7-1 Breast Neoplasms 23720754 MicroRNA-7 Suppresses the Invasive Potential of Breast Cancer Cells and Sensitizes Cells to DNA Damages by Targeting Histone Methyltransferase SET8. 10042 hsa-mir-7-2 Breast Neoplasms 23720754 MicroRNA-7 Suppresses the Invasive Potential of Breast Cancer Cells and Sensitizes Cells to DNA Damages by Targeting Histone Methyltransferase SET8. 10043 hsa-mir-7-3 Breast Neoplasms 23720754 MicroRNA-7 Suppresses the Invasive Potential of Breast Cancer Cells and Sensitizes Cells to DNA Damages by Targeting Histone Methyltransferase SET8. 10044 hsa-mir-34c Osteosarcoma 23720736 MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma. 10045 hsa-mir-125b-1 Carcinoma, Non-Small-Cell Lung 23718732 MTA1 promotes the invasion and migration of non-small cell lung cancer cells by downregulating miR-125b. 10046 hsa-mir-125b-2 Carcinoma, Non-Small-Cell Lung 23718732 MTA1 promotes the invasion and migration of non-small cell lung cancer cells by downregulating miR-125b. 10047 hsa-mir-506 Breast Neoplasms 23717581 miR-506 Regulates Epithelial Mesenchymal Transition in Breast Cancer Cell Lines. 10048 hsa-mir-155 Pancreatic Neoplasms 23715647 MLH1 as a Direct Target of MiR-155 and a Potential Predictor of Favorable Prognosis in Pancreatic Cancer. 10049 hsa-mir-135a-1 Lung Neoplasms 23715500 A microRNA-135a/b binding polymorphism in CD133 confers decreased risk and favorable prognosis of lung cancer in Chinese by reducing CD133 expression. 10050 hsa-mir-135a-2 Lung Neoplasms 23715500 A microRNA-135a/b binding polymorphism in CD133 confers decreased risk and favorable prognosis of lung cancer in Chinese by reducing CD133 expression. 10051 hsa-mir-135b Lung Neoplasms 23715500 A microRNA-135a/b binding polymorphism in CD133 confers decreased risk and favorable prognosis of lung cancer in Chinese by reducing CD133 expression. 10052 hsa-mir-137 Glioblastoma 23714687 MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1. 10053 hsa-mir-328 Atrial Fibrillation 23710743 miR-328 expression is significantly increased in patients with AF 10054 hsa-mir-197 HBV Infection 23710316 miR-197 Expression in Peripheral Blood Mononuclear Cells from Hepatitis B Virus-Infected Patients. 10055 hsa-mir-335 Ovarian Neoplasms 23708561 miR-335 represents an invasion suppressor gene in ovarian cancer by targeting Bcl-w. 10056 hsa-mir-146a Hepatitis B 23698745 MicroRNA-146a Feedback Suppresses T Cell Immune Function by Targeting Stat1 in Patients with Chronic Hepatitis B. 10057 hsa-mir-375 Ovarian Neoplasms 23696927 Mir-375 enhances ruthenium-derived compound Rawq01 induced cell death in human ovarian cancer. 10058 hsa-mir-339 Colorectal Neoplasms 23696794 MiR-339-5p Regulates the Growth, Colony Formation and Metastasis of Colorectal Cancer Cells by Targeting PRL-1. 10059 hsa-mir-192-2 Esophageal Neoplasms 23677061 miR-129-2 suppresses proliferation and migration of esophageal carcinoma cells through downregulation of SOX4 expression. 10060 hsa-mir-150 Pancreatic Neoplasms 23675407 Upregulation of miR-150* and miR-630 Induces Apoptosis in Pancreatic Cancer Cells by Targeting IGF-1R. 10061 hsa-mir-630 Pancreatic Neoplasms 23675407 Upregulation of miR-150* and miR-630 Induces Apoptosis in Pancreatic Cancer Cells by Targeting IGF-1R. 10062 hsa-mir-18a Colorectal Neoplasms 23673725 Serum miR-18a and miR-29a could be promising biomarkers for the screening and monitoring of CRC patients. 10063 hsa-mir-29a Colorectal Neoplasms 23673725 Serum miR-18a and miR-29a could be promising biomarkers for the screening and monitoring of CRC patients. 10064 hsa-mir-497 Carcinoma, Non-Small-Cell Lung 23673296 Downregulation of miR-497 promotes tumor growth and angiogenesis by targeting HDGF in non-small cell lung cancer. 10065 hsa-mir-146a Carcinoma, Hepatocellular 23671131 MiR-146a enhances angiogenic activity of endothelial cells in hepatocellular carcinoma by promoting PDGFRA expression. 10066 hsa-mir-186 Carcinoma, Non-Small-Cell Lung 23671127 PTTG1 promotes migration and invasion of human non-small cell lung cancer cells and is modulated by miR-186. 10067 hsa-mir-148a Carcinoma, Non-Small-Cell Lung 23670799 MicroRNA-148a suppresses epithelial-to-mesenchymal transition by targeting ROCK1 in non-small cell lung cancer cells. 10068 hsa-mir-10b Ovarian Neoplasms 23670532 Loss of HOXD10 expression induced by upregulation of miR-10b accelerates the migration and invasion activities of ovarian cancer cells. 10069 hsa-mir-129-1 Carcinoma, Hepatocellular 23580407 Frequent DNA methylation of MiR-129-2 and its potential clinical implication in hepatocellular carcinoma 10070 hsa-mir-129-2 Carcinoma, Hepatocellular 23580407 Frequent DNA methylation of MiR-129-2 and its potential clinical implication in hepatocellular carcinoma 10071 hsa-mir-221 HEV 23579640 Identification of miR-221 and -222 as important regulators in genotype IV swine hepatitis E virus ORF3-expressing HEK 293 cells 10072 hsa-mir-222 HEV 23579640 Identification of miR-221 and -222 as important regulators in genotype IV swine hepatitis E virus ORF3-expressing HEK 293 cells 10073 hsa-mir-18a Carcinoma, Squamous Cell 23579215 Clinical impact of circulating miR-18a in plasma of patients with oesophageal squamous cell carcinoma 10074 hsa-mir-24-1 Osteosarcoma 23578572 MicroRNA-24 Inhibits Osteosarcoma Cell Proliferation Both In Vitro and In Vivo by Targeting LPAATʇ 10075 hsa-mir-24-2 Osteosarcoma 23578572 MicroRNA-24 Inhibits Osteosarcoma Cell Proliferation Both In Vitro and In Vivo by Targeting LPAATʇ 10076 hsa-mir-345 Carcinoma, Hepatocellular 23577194 Hepatitis C Virus Core Protein Down-Regulates p21(Waf1/Cip1) and Inhibits Curcumin-Induced Apoptosis through MicroRNA-345 Targeting in Human Hepatoma Cells 10077 hsa-mir-370 Gastric Neoplasms 23576572 Fork head box M1 is overexpressed in Helicobacter pylori-induced gastric carcinogenesis and is negatively regulated by hsa-miR-370 10078 hsa-mir-19b-1 Osteosarcoma 23574781 MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma 10079 hsa-mir-19b-2 Osteosarcoma 23574781 MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma 10080 hsa-mir-143 Colorectal Neoplasms 23574723 MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers 10081 hsa-mir-301a Diabetes Mellitus 23573265 MicroRNA-301a Mediated Regulation of Kv4.2 in Diabetes: Identification of Key Modulators 10082 hsa-mir-107 Glioma 23572380 MicroRNA-107 Inhibits U87 Glioma Stem Cells Growth and Invasion 10083 hsa-mir-205 Prostatic Neoplasms 23571738 miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients 10084 hsa-mir-26 Carcinoma, Hepatocellular 23569435 Development of a miR-26 Companion Diagnostic Test for Adjuvant Interferon-alpha Therapy in Hepatocellular Carcinoma 10085 hsa-mir-34a Osteosarcoma 23569431 MicroRNA-34a Inhibits Human Osteosarcoma Proliferation by Downregulating Ether go-go 1 Expression 10086 hsa-mir-221 Ovarian Neoplasms 23569131 Prognostic significance of serum microRNA-221 expression in human epithelial ovarian cancer 10087 hsa-mir-708 Bladder Neoplasms 23568547 miR-708 promotes the development of bladder carcinoma via direct repression of Caspase-2 10088 hsa-mir-155 Breast Neoplasms 23568502 17ʇ-Estradiol up-regulates miR-155 expression and reduces TP53INP1 expression in MCF-7 breast cancer cells 10089 hsa-mir-221 Leukemia, lymphoblastic, Acute 23566596 Increased expression of miR-221 is associated with shorter overall survival in T-cell acute lymphoid leukemia 10090 hsa-mir-383 Glioma 23564324 Downregulation of miR-383 promotes glioma cell invasion by targeting insulin-like growth factor 1 receptor 10091 hsa-mir-10b Thyroid Neoplasms 23563786 The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma 10092 hsa-mir-221 Thyroid Neoplasms 23563786 The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma 10093 hsa-mir-222 Thyroid Neoplasms 23563786 The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma 10094 hsa-mir-92a-1 Thyroid Neoplasms 23563786 The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma 10095 hsa-mir-92a-2 Thyroid Neoplasms 23563786 The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma 10096 hsa-mir-138-1 Neuroblastoma 23562653 miR-138 Overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivo 10097 hsa-mir-138-2 Neuroblastoma 23562653 miR-138 Overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivo 10098 hsa-mir-155 Diabetes Mellitus 23560074 Bone Marrow Progenitor Cell Therapy-Mediated Paracrine Regulation of Cardiac miRNA-155 Modulates Fibrotic Response in Diabetic Hearts 10099 hsa-mir-141 Azoospermia 23559187 Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p 10100 hsa-mir-429 Azoospermia 23559187 Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p 10101 hsa-mir-7-1 Azoospermia 23559187 Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p 10102 hsa-mir-7-2 Azoospermia 23559187 Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p 10103 hsa-mir-7-3 Azoospermia 23559187 Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p 10104 hsa-mir-21 Carcinoma, Renal Cell 23558936 MiR-21 is overexpressed in RCC tissue and modulates the growth, apoptosis and cell cycle progression of RCC cells and regulates the expression of PDCD4 and TPM1 10105 hsa-mir-874 Neoplasms, Squamous Cell 23558898 Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma 10106 hsa-mir-146a Lung Neoplasms 23555954 miR-146a Inhibits Cell Growth, Cell Migration and Induces Apoptosis in Non-Small Cell Lung Cancer Cells 10107 hsa-mir-221 HIV 23555914 HIV Tat Induces Expression of ICAM-1 in HUVECs: Implications for miR-221/-222 in HIV-Associated Cardiomyopathy 10108 hsa-mir-222 HIV 23555914 HIV Tat Induces Expression of ICAM-1 in HUVECs: Implications for miR-221/-222 in HIV-Associated Cardiomyopathy 10109 hsa-mir-574 Prostate Neoplasms 23554959 Genistein Up-Regulates Tumor Suppressor MicroRNA-574-3p in Prostate Cancer 10110 hsa-mir-1228 Stomach Neoplasms 23554909 Restoration of miR-1228* Expression Suppresses Epithelial-Mesenchymal Transition in Gastric Cancer 10111 hsa-mir-583 Hepatitis B 23554832 Circulating miR-583 and miR-663 Refer to ZHENG Differentiation in Chronic Hepatitis B 10112 hsa-mir-663 Hepatitis B 23554832 Circulating miR-583 and miR-663 Refer to ZHENG Differentiation in Chronic Hepatitis B 10113 hsa-mir-429 Gastric Neoplasms 23554776 miRNA-429 may serve as a tumor suppressor during tumorigenesis of gastric cancer and may be a potential gastric cancer therapeutic target 10114 hsa-mir-101-1 HIV 23554480 HIV-1 Tat C Modulates Expression of miRNA-101 to Suppress VE-Cadherin in Human Brain Microvascular Endothelial Cells 10115 hsa-mir-101-2 HIV 23554480 HIV-1 Tat C Modulates Expression of miRNA-101 to Suppress VE-Cadherin in Human Brain Microvascular Endothelial Cells 10116 hsa-mir-23a Gastric Neoplasms 23553990 MiR-23a in Amplified 19p13.13 Loci Targets Metallothionein 2A and Promotes Growth in Gastric Cancer Cells 10117 hsa-mir-31 Ovarian Neoplasms 23552883 Downregulation of miRNA-31 induces taxane resistance in ovarian cancer cells through increase of receptor tyrosine kinase MET 10118 hsa-mir-139 Glioma 23551751 MiR-139 Inhibits Mcl-1 Expression and Potentiates TMZ-Induced Apoptosis in Glioma 10119 hsa-mir-148a Gastric Neoplasms 23549984 MicroRNA-148a can regulate runt-related transcription factor 3 gene expression via modulation of DNA methyltransferase 1 in gastric cancer 10120 hsa-mir-515-1 Breast Neoplasms 23549953 Involvement of IGF-1R regulation by miR-515-5p modifies breast cancer risk among BRCA1 carriers 10121 hsa-mir-515-2 Breast Neoplasms 23549953 Involvement of IGF-1R regulation by miR-515-5p modifies breast cancer risk among BRCA1 carriers 10122 hsa-mir-145 Carcinoma, Squamous Cell 23548968 Downregulation of miR-145 Expression in Oral Squamous Cell Carcinomas and Its Clinical Significance 10123 hsa-mir-21 Lymphoma, B-Cell 23548551 Inhibition of miR-21 Induces Biological and Behavioral Alterations in Diffuse Large B-Cell Lymphoma 10124 hsa-mir-145 Head and Neck Neoplasms 23548270 miR145 targets the SOX9/ADAM17 axis to inhibit tumor initiating cells and IL-6-mediated paracrine effects in head and neck cancer 10125 hsa-mir-150 Myocardial Infarction 23547171 MicroRNA-150: A Novel Marker of Left Ventricular Remodeling After Acute Myocardial Infarction 10126 hsa-mir-144 Alzheimer Disease 23546882 MicroRNA-144 Is Regulated by Activator Protein-1 (AP-1) and Decreases Expression of Alzheimer's Disease-related A Disintegrin And Metalloprotease 10 (ADAM10) 10127 hsa-mir-92 Carcinoma, Hepatocellular 23546593 Expression and significance of PTEN and miR-92 in hepatocellular carcinoma 10128 hsa-mir-200c Breast Neoplasms 23546450 miRNA-200c increases the sensitivity of breast cancer cells to doxorubicin through the suppression of E-cadherin-mediated PTEN/Akt signaling 10129 hsa-mir-21 Colonic Neoplasms 23544170 Down-regulation of miR-21 Induces Differentiation of Chemoresistant Colon Cancer Cells and Enhances Susceptibility to Therapeutic Regimens 10130 hsa-mir-195 Carcinoma, Hepatocellular 23544130 The Tumor-Suppressive miR-497-195 Cluster Targets Multiple Cell-Cycle Regulators in Hepatocellular Carcinoma 10131 hsa-mir-497 Carcinoma, Hepatocellular 23544130 The Tumor-Suppressive miR-497-195 Cluster Targets Multiple Cell-Cycle Regulators in Hepatocellular Carcinoma 10132 hsa-mir-200b Glioma 23543137 MicroRNA-200b targets CREB1 and suppresses cell growth in human malignant glioma 10133 hsa-mir-191 Breast Neoplasms 23542418 MicroRNA-191, an estrogen responsive microRNA, functions as an oncogenic regulator in human breast cancer 10134 hsa-mir-31 Neoplasms 23539435 MicroRNA-31-5p modulates cell cycle by targeting human mutL homolog 1 in human cancer cells 10135 hsa-mir-183 Prostate Neoplasms 23538390 microRNA-183 is an oncogene targeting Dkk-3 and SMAD4 in prostate cancer 10136 hsa-mir-122 HCV 23537271 Down-regulating miR-122 expression by HCV core protein may give a new insight into the interaction between HCV and miR-122 and chronic HCV infection 10137 hsa-mir-34a Neoplasms 23533633 CD24 Induces Expression of the Oncomir miR-21 via Src, and CD24 and Src Are Both Post-Transcriptionally Downregulated by the Tumor Suppressor miR-34a 10138 hsa-mir-18a Glioma 23533157 Tumorigenic Potential of miR-18A* in Glioma Initiating Cells Requires NOTCH-1 Signaling 10139 hsa-mir-215 Colorectal Neoplasms 23532818 MicroRNA-215 inhibits relapse of colorectal cancer patients following radical surgery 10140 hsa-mir-497 Neuroblastoma 23531080 MicroRNA-497 increases apoptosis in MYCN amplified neuroblastoma cells by targeting the key cell cycle regulator WEE1 10141 hsa-mir-27a Colorectal Neoplasms 23530649 Resveratrol and Quercetin in Combination Have Anticancer Activity in Colon Cancer Cells and Repress Oncogenic microRNA-27a 10142 hsa-mir-9-1 Breast Neoplasms 23530058 miR-9-3p targets integrin beta 1 to sensitize claudin-low breast cancer cells to MEK inhibition 10143 hsa-mir-9-2 Breast Neoplasms 23530058 miR-9-3p targets integrin beta 1 to sensitize claudin-low breast cancer cells to MEK inhibition 10144 hsa-mir-9-3 Breast Neoplasms 23530058 miR-9-3p targets integrin beta 1 to sensitize claudin-low breast cancer cells to MEK inhibition 10145 hsa-mir-34a Glioma 23529798 These findings indicate the role of miR-34a in tumor progression may be closely associated with p53 mutation and inversely correlated to Bcl-2 expression 10146 hsa-mir-22 Stomach Neoplasms 23529765 miR-22 is down-regulated in gastric cancer, and its overexpression inhibits cell migration and invasion via targeting transcription factor Sp1 10147 hsa-mir-125b-1 Lymphoma, T-Cell 23527180 cMyc/miR-125b-5p Signalling Determines Sensitivity to Bortezomib in Preclinical Model of Cutaneous T-Cell Lymphomas 10148 hsa-mir-125b-2 Lymphoma, T-Cell 23527180 cMyc/miR-125b-5p Signalling Determines Sensitivity to Bortezomib in Preclinical Model of Cutaneous T-Cell Lymphomas 10149 hsa-mir-128-1 Breast Neoplasms 23526655 Downregulation of miRNA-128 sensitizes breast cancer cell to chemodrugs by targeting Bax 10150 hsa-mir-128-2 Breast Neoplasms 23526655 Downregulation of miRNA-128 sensitizes breast cancer cell to chemodrugs by targeting Bax 10151 hsa-mir-195 Colorectal Neoplasms 23526568 MicroRNA-195 chemosensitizes colon cancer cells to the chemotherapeutic drug doxorubicin by targeting the first binding site of BCL2L2 mRNA 10152 hsa-mir-34a Leukemia, lymphoblastic, Chronic 23525797 Inactivation of TP53 correlates with disease progression and low miR-34a expression in previously treated chronic lymphocytic leukemia patients 10153 hsa-mir-26a-1 Pituitary Adenomas 23525216 miR-26a Plays an Important Role in Cell Cycle Regulation in ACTH-Secreting Pituitary Adenomas by Modulating Protein Kinase C 10154 hsa-mir-26a-2 Pituitary Adenomas 23525216 miR-26a Plays an Important Role in Cell Cycle Regulation in ACTH-Secreting Pituitary Adenomas by Modulating Protein Kinase C 10155 hsa-mir-200 Breast Neoplasms 23525011 Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem cell-like state 10156 hsa-mir-181 Breast Neoplasms 23524334 Activin and TGFʇ regulate expression of the microRNA-181 family to promote cell migration and invasion in breast cancer cells 10157 hsa-mir-222 Leukemia, Acute 23522449 MicroRNA profiling reveals aberrant microRNA expression in adult ETP-ALL and functional studies implicate a role for miR-222 in acute leukemia 10158 hsa-mir-20a Stomach Neoplasms 23521833 The levels of serum miR-20a-5p, let-7a and miR-320a were positively correlated with PGA/PGC, which may indirectly reflect the functional status of the gastric mucosa. 10159 hsa-mir-320a Stomach Neoplasms 23521833 The levels of serum miR-20a-5p, let-7a and miR-320a were positively correlated with PGA/PGC, which may indirectly reflect the functional status of the gastric mucosa. 10160 hsa-mir-150 Lymphoma 23521217 Re-expression of miR-150 induces EBV-positive Burkitt lymphoma differentiation by modulating c-Myb in vitro 10161 hsa-mir-125a Breast Neoplasms 23519125 Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells 10162 hsa-mir-125b-1 Breast Neoplasms 23519125 Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells 10163 hsa-mir-125b-2 Breast Neoplasms 23519125 Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells 10164 hsa-mir-205 Breast Neoplasms 23519125 Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells 10165 hsa-mir-196a-1 HBV Infection 23516510 Associations of pri-miR-34b/c and pre-miR-196a2 Polymorphisms and Their Multiplicative Interactions with Hepatitis B Virus Mutations with Hepatocellular Carcinoma Risk 10166 hsa-mir-196a-2 HBV Infection 23516510 Associations of pri-miR-34b/c and pre-miR-196a2 Polymorphisms and Their Multiplicative Interactions with Hepatitis B Virus Mutations with Hepatocellular Carcinoma Risk 10167 hsa-mir-34b HBV Infection 23516510 Associations of pri-miR-34b/c and pre-miR-196a2 Polymorphisms and Their Multiplicative Interactions with Hepatitis B Virus Mutations with Hepatocellular Carcinoma Risk 10168 hsa-mir-34c HBV Infection 23516510 Associations of pri-miR-34b/c and pre-miR-196a2 Polymorphisms and Their Multiplicative Interactions with Hepatitis B Virus Mutations with Hepatocellular Carcinoma Risk 10169 hsa-mir-29c Brain Injury 23516428 MicroRNA miR-29c Down-Regulation Leading to De-Repression of Its Target DNA Methyltransferase 3a Promotes Ischemic Brain Damage 10170 hsa-mir-155 Atherosclerosis 23513069 The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1-and microRNA-155-Dependent Pathway during Atherosclerosis 10171 hsa-mir-342 Atherosclerosis 23513069 The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1-and microRNA-155-Dependent Pathway during Atherosclerosis 10172 hsa-mir-9-1 Leukemia 23509296 a unique role of miR-9 in myelopoiesis and in the pathogenesis of EVI1-induced myeloid neoplasms and provide insights into the epigenetic regulation of miR9 in tumorigenesis 10173 hsa-mir-9-2 Leukemia 23509296 a unique role of miR-9 in myelopoiesis and in the pathogenesis of EVI1-induced myeloid neoplasms and provide insights into the epigenetic regulation of miR9 in tumorigenesis 10174 hsa-mir-9-3 Leukemia 23509296 a unique role of miR-9 in myelopoiesis and in the pathogenesis of EVI1-induced myeloid neoplasms and provide insights into the epigenetic regulation of miR9 in tumorigenesis 10175 hsa-mir-122 HBV Infection 23508904 Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B 10176 hsa-mir-22 HBV Infection 23508904 Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B 10177 hsa-mir-9-1 HIV Infection 23508624 Modulation of BK Channel by MicroRNA-9 in Neurons After Exposure to HIV and Methamphetamine 10178 hsa-mir-16-1 Osteosarcoma 23507142 miR-16 inhibits cell proliferation by targeting IGF1R and the Raf1-MEK1/2-ERK1/2 pathway in osteosarcoma 10179 hsa-mir-16-2 Osteosarcoma 23507142 miR-16 inhibits cell proliferation by targeting IGF1R and the Raf1-MEK1/2-ERK1/2 pathway in osteosarcoma 10180 hsa-mir-625 Colorectal Neoplasms 23506979 High expression of microRNA-625-3p is associated with poor response to first-line oxaliplatin based treatment of metastatic colorectal cancer 10181 hsa-mir-191 Breast Neoplasms 23505378 Estrogen Mediated-Activation of miR-191/425 Cluster Modulates Tumorigenicity of Breast Cancer Cells Depending on Estrogen Receptor Status 10182 hsa-mir-425 Breast Neoplasms 23505378 Estrogen Mediated-Activation of miR-191/425 Cluster Modulates Tumorigenicity of Breast Cancer Cells Depending on Estrogen Receptor Status 10183 hsa-mir-34b Nasopharyngeal Neoplasms 23504554 Interactions of miR-34b/c and TP-53 polymorphisms on the risk of nasopharyngeal carcinoma 10184 hsa-mir-34c Nasopharyngeal Neoplasms 23504554 Interactions of miR-34b/c and TP-53 polymorphisms on the risk of nasopharyngeal carcinoma 10185 hsa-mir-21 Esophageal Neoplasms 23504349 miR-21 Down-Regulation Suppresses Cell Growth, Invasion and Induces Cell Apoptosis by Targeting FASL, TIMP3, and RECK Genes in Esophageal Carcinoma 10186 hsa-mir-125b-1 Prostate Neoplasms 23503464 Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells 10187 hsa-mir-125b-2 Prostate Neoplasms 23503464 Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells 10188 hsa-mir-99a Prostate Neoplasms 23503464 Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells 10189 hsa-mir-145 Carcinoma, Hepatocellular 23499894 MiR-145 functions as a tumor suppressor by directly targeting histone deacetylase 2 in liver cancer 10190 hsa-mir-145 Colorectal Neoplasms 23499891 Tumor-suppressive microRNA-145 targets catenin to regulate Wnt/beta-catenin signaling in human colon cancer cells 10191 hsa-mir-92a-1 Ovarian Neoplasms 23499550 miR-92a Inhibits Peritoneal Dissemination of Ovarian Cancer Cells by Inhibiting Integrin Expression. 10192 hsa-mir-92a-2 Ovarian Neoplasms 23499550 miR-92a Inhibits Peritoneal Dissemination of Ovarian Cancer Cells by Inhibiting Integrin ϫ5 Expression. 10193 hsa-mir-155 Leukemia, Myeloid, Acute 23497456 Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia 10194 hsa-mir-125b-1 Neoplasms 23497288 miR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor 10195 hsa-mir-125b-2 Neoplasms 23497288 miR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor 10196 hsa-mir-93 Ovary Syndrome 23493574 miRNA-93 inhibits GLUT4 and is overexpressed in adipose tissue of Polycystic Ovary Syndrome patients and women with insulin resistance 10197 hsa-mir-29b-1 Leukemia, Myeloid, Acute 23493348 Targeted Delivery of microRNA-29b by Transferrin Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia 10198 hsa-mir-29b-2 Leukemia, Myeloid, Acute 23493348 Targeted Delivery of microRNA-29b by Transferrin Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia 10199 hsa-mir-210 Lung Neoplasms 23492775 MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines 10200 hsa-mir-205 Neoplasms 23487795 Arf tumor suppressor and miR-205 regulate cell adhesion and formation of extraembryonic endoderm from pluripotent stem cells 10201 hsa-mir-195 Carcinoma, Hepatocellular 23487264 Genome-wide screening revealed that miR-195 targets the TNF-alpha/NF-kB pathway by downregulating IKK and TAB3 in hepatocellular carcinoma 10202 hsa-mir-30a Colorectal Neoplasms 23486085 miR-30a Suppresses Cell Migration and Invasion Through Downregulation of PIK3CD in Colorectal Carcinoma 10203 hsa-mir-106b Carcinoma, Hepatocellular 23483935 Over-Expression of miR-106b Promotes Cell Migration and Metastasis in Hepatocellular Carcinoma by Activating Epithelial-Mesenchymal Transition Process 10204 hsa-mir-218-1 Cervical Neoplasms 23483249 Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion by targeting focal adhesion pathways in cervical squamous cell carcinoma 10205 hsa-mir-218-2 Cervical Neoplasms 23483249 Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion by targeting focal adhesion pathways in cervical squamous cell carcinoma 10206 hsa-mir-101-1 Carcinoma, Hepatocellular 23483142 miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells 10207 hsa-mir-101-2 Carcinoma, Hepatocellular 23483142 miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells 10208 hsa-mir-128-1 Glioblastoma 23482671 NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200 10209 hsa-mir-128-2 Glioblastoma 23482671 NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200 10210 hsa-mir-200 Glioblastoma 23482671 NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200 10211 hsa-mir-21 Glioblastoma 23482671 NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200 10212 hsa-mir-145 Prostate Neoplasms 23480797 The proto-oncogene ERG is a target of microRNA miR-145 in prostate cancer 10213 hsa-mir-584 Breast Neoplasms 23479725 Micro-RNA-584 and the protein phosphatase and actin regulator 1 (PHACTR1): New Signaling Route Through Which Transforming Growth Factor-Beta Mediates the Migration and Actin Dynamics of Breast Cancer Cells 10214 hsa-mir-221 Multiple Myeloma 23479461 In Vitro and in Vivo Anti-tumor Activity of miR-221/222 Inhibitors in Multiple Myeloma 10215 hsa-mir-222 Multiple Myeloma 23479461 In Vitro and in Vivo Anti-tumor Activity of miR-221/222 Inhibitors in Multiple Myeloma 10216 hsa-mir-214 Nasopharyngeal Neoplasms 23479198 miR-214 promotes tumorigenesis by targeting lactotransferrin in nasopharyngeal carcinoma 10217 hsa-mir-612 Carcinoma, Hepatocellular 23478189 miR-612 suppresses the invasive-metastatic cascade in hepatocellular carcinoma 10218 hsa-mir-486 Lung Neoplasms 23474761 Downregulation of miR-486-5p contributes to tumor progression and metastasis by targeting protumorigenic ARHGAP5 in lung cancer 10219 hsa-mir-182 Breast Neoplasms 23474751 Suppression of MIM by microRNA-182 activates RhoA and promotes breast cancer metastasis 10220 hsa-mir-182 Colorectal Neoplasms 23474644 Up-regulation of miR-182 expression in colorectal cancer tissues and its prognostic value 10221 hsa-mir-27a Carcinoma, Oral 23472065 Primary Microcephaly Gene MCPH1 Shows Signatures of Tumor Suppressors and Is Regulated by miR-27a in Oral Squamous Cell Carcinoma 10222 hsa-mir-27a Colorectal Neoplasms 23471840 The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis 10223 hsa-mir-216a Carcinoma, Hepatocellular 23471579 MiR-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer 10224 hsa-mir-217 Carcinoma, Hepatocellular 23471579 MiR-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer 10225 hsa-mir-3148 Lupus Erythematosus, Systemic 23468661 MicroRNA-3148 Modulates Allelic Expression of Toll-Like Receptor 7 Variant Associated with Systemic Lupus Erythematosus 10226 hsa-mir-195 Carcinoma, Hepatocellular 23468064 MicroRNA-195 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting the expression of VEGF, VAV2 and CDC42 10227 hsa-mir-134 Glioblastoma 23467648 MiR-134 regulates the proliferation and invasion of glioblastoma cells by reducing Nanog expression 10228 hsa-mir-371 Carcinoma, Hepatocellular 23466643 miR-371-5p down-regulates pre mRNA processing factor 4 homolog B (PRPF4B) and facilitates the G1/S transition in human hepatocellular carcinoma cells 10229 hsa-mir-21 Stomach Neoplasms 23466500 miR-21 confers cisplatin resistance in gastric cancer cells by regulating PTEN 10230 hsa-mir-206 Breast Neoplasms 23466356 miR-206 is down-regulated in breast cancer and inhibits cell proliferation through the up-regulation of cyclinD2 10231 hsa-mir-126 Heart Failure 23465244 Expression of miR-126 and miR-508-5p in endothelial progenitor cells is associated with the prognosis of chronic heart failure patients 10232 hsa-mir-508 Heart Failure 23465244 Expression of miR-126 and miR-508-5p in endothelial progenitor cells is associated with the prognosis of chronic heart failure patients 10233 hsa-mir-129-1 Lymphoma, Large B-Cell, Diffuse 23463124 Low expression of microRNA-129-5p predicts poor clinical outcome in diffuse large B cell lymphoma (DLBCL) 10234 hsa-mir-129-2 Lymphoma, Large B-Cell, Diffuse 23463124 Low expression of microRNA-129-5p predicts poor clinical outcome in diffuse large B cell lymphoma (DLBCL) 10235 hsa-mir-152 Prostatic Neoplasms 23460133 miR-152 controls migration and invasive potential by targeting TGFϫ in prostate cancer cell lines 10236 hsa-mir-126 Cholangiocarcinoma 23458262 Concomitant dysregulation of microRNAs miR-151-3p and miR-126 correlates with improved survival in resected cholangiocarcinoma 10237 hsa-mir-151 Cholangiocarcinoma 23458262 Concomitant dysregulation of microRNAs miR-151-3p and miR-126 correlates with improved survival in resected cholangiocarcinoma 10238 hsa-mir-17 Breast Neoplasms 18695042 A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. 10239 hsa-mir-20a Breast Neoplasms 18695042 A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. 10240 hsa-mir-146b Glioma 19265686 microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs. 10241 hsa-mir-101-1 Stomach Neoplasms 20712078 miR-101-3p: MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion 10242 hsa-mir-101-2 Stomach Neoplasms 20712078 miR-101-3p: MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion 10243 hsa-mir-21 Osteosarcoma 20480266 MicroRNA-21 is involved in osteosarcoma cell invasion and migration. 10244 hsa-mir-21 Carcinoma, Squamous Cell 20831814 Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma. 10245 hsa-mir-203 Carcinoma, Hepatocellular 22886454 miR-203 inhibits proliferation of HCC cells by targeting surviving. 10246 hsa-let-7a Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 10247 hsa-let-7b Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 10248 hsa-let-7d Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 10249 hsa-let-7g Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 10250 hsa-let-7a Stomach Neoplasms 18413822 Clinical significance of high mobility group A2 in human gastric cancer and its relationship to let-7 microRNA family. 10251 hsa-mir-17 Breast Neoplasms 18695042 A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. 10252 hsa-mir-20a Breast Neoplasms 18695042 A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. 10253 hsa-mir-146b Glioma 19265686 microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs. 10254 hsa-mir-101-1 Stomach Neoplasms 20712078 miR-101-3p: MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion 10255 hsa-mir-101-2 Stomach Neoplasms 20712078 miR-101-3p: MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion 10256 hsa-mir-21 Osteosarcoma 20480266 MicroRNA-21 is involved in osteosarcoma cell invasion and migration. 10257 hsa-mir-21 Carcinoma, Squamous Cell 20831814 Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma. 10258 hsa-mir-203 Carcinoma, Hepatocellular 22886454 miR-203 inhibits proliferation of HCC cells by targeting surviving. 10259 hsa-let-7a-1 Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 10260 hsa-let-7a-2 Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 10261 hsa-let-7a-3 Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 10262 hsa-let-7b Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 10263 hsa-let-7d Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 10264 hsa-let-7g Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 10265 hsa-let-7a Stomach Neoplasms 18413822 Clinical significance of high mobility group A2 in human gastric cancer and its relationship to let-7 microRNA family. 10266 hsa-mir-34a Neuroblastoma 18505919 A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene. 10267 hsa-mir-34a Neuroblastoma 18505919 A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene. 10268 hsa-mir-372 Testicular Neoplasms 16564011 A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. 10269 hsa-mir-373 Testicular Neoplasms 16564011 A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. 10270 hsa-let-7c Leiomyoma 17243163 HMGA2 was identified as one of target genes of the let-7 family of miRNAs and has been found to be suppressed by let-7 in vitro. 10271 hsa-mir-125b Breast Neoplasms 19738052 A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis. 10272 hsa-mir-128 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 10273 hsa-mir-485 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 10274 hsa-mir-509 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 10275 hsa-mir-765 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 10276 hsa-mir-148a Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 10277 hsa-mir-148b Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 10278 hsa-mir-152 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 10279 hsa-mir-146a Alzheimer Disease 18801740 An NF-kB-sensitive microRNA-146a-mediated inflammatory circuit in Alzheimer's disease and in stressed human brain cells. 10280 hsa-mir-17 Neuroblastoma 18493594 Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM 10281 hsa-mir-17 Neuroblastoma 18493594 Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM 10282 hsa-mir-127 Burkitt Lymphoma 19530237 B cell differentiation in EBV-positive Burkitt Lymphoma is impaired at post-transcriptional level by miRNA altered expression. 10283 hsa-mir-127 Burkitt Lymphoma 19530237 B cell differentiation in EBV-positive Burkitt Lymphoma is impaired at post-transcriptional level by miRNA altered expression. 10284 hsa-mir-182 Breast Neoplasms 19574223 Coordinate Regulation of FOXO1 by miR-27a, miR-96, and miR-182 in Breast Cancer Cells. 10285 hsa-mir-27a Breast Neoplasms 19574223 Coordinate Regulation of FOXO1 by miR-27a, miR-96, and miR-182 in Breast Cancer Cells. 10286 hsa-mir-96 Breast Neoplasms 19574223 Coordinate Regulation of FOXO1 by miR-27a, miR-96, and miR-182 in Breast Cancer Cells. 10287 hsa-mir-221 Glioma 19424584 Co-suppression of miR-221/222 cluster suppresses human glioma cell growth by targeting p27kip1 in vitro and in vivo. 10288 hsa-mir-222 Glioma 19424584 Co-suppression of miR-221/222 cluster suppresses human glioma cell growth by targeting p27kip1 in vitro and in vivo. 10289 hsa-mir-122 Carcinoma, Hepatocellular 17616664 Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. 10290 hsa-mir-106a Colon Neoplasms 18521848 Deregulated expression of miR-106a predicts survival in human colon cancer patients. 10291 hsa-mir-17 Colon Neoplasms 18521848 Deregulated expression of miR-106a predicts survival in human colon cancer patients. 10292 hsa-mir-143 Lymphoma, B-Cell 17892514 Downregulation of microRNAs-143 and -145 in B-cell malignancies. 10293 hsa-mir-143 Lymphoma, B-Cell 17892514 Downregulation of microRNAs-143 and -145 in B-cell malignancies. 10294 hsa-mir-1-1 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 10295 hsa-mir-1-2 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 10296 hsa-mir-133a-1 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 10297 hsa-mir-133a-2 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 10298 hsa-mir-133a-1 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 10299 hsa-mir-133a-2 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 10300 hsa-mir-133b Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 10301 hsa-mir-133b Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 10302 hsa-mir-10b Fatty Liver, Non-Alcoholic 19780876 Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-alpha expression, a novel mechanism for the pathogenesis of NAFLD 10303 hsa-mir-510 Irritable Bowel Syndrome 18614545 First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor type 3E gene with diarrhea predominant irritable bowel syndrome. 10304 hsa-let-7a-1 Melanoma 18679415 Integrin beta(3) expression is regulated by let-7a miRNA in malignant melanoma. 10305 hsa-let-7a-2 Melanoma 18679415 Integrin beta(3) expression is regulated by let-7a miRNA in malignant melanoma. 10306 hsa-let-7a-3 Melanoma 18679415 Integrin beta(3) expression is regulated by let-7a miRNA in malignant melanoma. 10307 hsa-mir-145 Colon Neoplasms 17827156 Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. 10308 hsa-mir-210 Lung Neoplasms 19654003 low expression, targets pro-survival molecules MCL-1 and BCL2L2 10309 hsa-mir-210 Lung Neoplasms 19654003 low expression, targets pro-survival molecules MCL-1 and BCL2L2 10310 hsa-mir-21 Glioma 18591254 MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. 10311 hsa-mir-21 Glioma 18591254 MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. 10312 hsa-let-7b Melanoma 18379589 MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. 10313 hsa-mir-1-1 Rhabdomyosarcoma 19710019 MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development. 10314 hsa-mir-1-2 Rhabdomyosarcoma 19710019 MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development. 10315 hsa-mir-206 Rhabdomyosarcoma 19710019 MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development. 10316 hsa-mir-125a Breast Neoplasms 19875930 MicroRNA-125a represses cell growth by targeting HuR in breast cancer 10317 hsa-mir-128 Glioma 18810376 MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. 10318 hsa-mir-215 Glioma 18810376 MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. 10319 hsa-mir-143 Colorectal Neoplasms 19638978 MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. 10320 hsa-mir-145 Prostatic Neoplasms 20332243 MicroRNA145 targets BNIP3 and suppresses prostate cancer progression. 10321 hsa-mir-15b Glioma 19135980 MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells. 10322 hsa-mir-21 Prostatic Neoplasms 19302977 MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells. 10323 hsa-mir-21 Glioblastoma 18829576 MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. 10324 hsa-mir-21 Glioblastoma 18829576 MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. 10325 hsa-mir-21 Glioblastoma 18829576 MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. 10326 hsa-mir-21 Glioblastoma 19559015 MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme. 10327 hsa-mir-21 Glioblastoma 19559015 MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme. 10328 hsa-mir-222 Carcinoma, Squamous Cell 19487542 MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1(MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cellcarcinoma cell lines. 10329 hsa-mir-222 Carcinoma, Squamous Cell 19487542 MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1(MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cellcarcinoma cell lines. 10330 hsa-mir-29a Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 10331 hsa-mir-29a Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 10332 hsa-mir-29b Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 10333 hsa-mir-29b Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 10334 hsa-mir-29c Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 10335 hsa-mir-29c Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 10336 hsa-mir-34a Glioblastoma 19773441 MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes 10337 hsa-mir-34a Glioblastoma 19773441 MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes 10338 hsa-mir-34a Glioblastoma 19773441 MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes 10339 hsa-mir-34a Glioblastoma 19773441 MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes 10340 hsa-mir-122 Carcinoma, Hepatocellular 18692484 miR-122 targets an anti-apoptotic gene, Bcl-w, in human hepatocellular carcinoma cell lines. 10341 hsa-mir-15b Stomach Neoplasms 18449891 miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. 10342 hsa-mir-16-1 Stomach Neoplasms 18449891 miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. 10343 hsa-mir-16-2 Stomach Neoplasms 18449891 miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. 10344 hsa-mir-206 Breast Neoplasms 18593897 miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer. 10345 hsa-mir-22 Breast Neoplasms 19414598 miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA. 10346 hsa-mir-221 Prostatic Neoplasms 17569667 miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1. 10347 hsa-mir-222 Prostatic Neoplasms 17569667 miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1. 10348 hsa-mir-34b Leukemia, Myeloid, Acute 19258499 miR-34b targets cyclic AMP-responsive element binding protein in acute myeloid leukemia. 10349 hsa-mir-449a Prostatic Neoplasms 19252524 miR-449a targets HDAC-1 and induces growth arrest in prostate cancer. 10350 hsa-mir-224 Carcinoma, Hepatocellular 18319255 Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target. 10351 hsa-mir-143 Colorectal Neoplasms 19137007 miR-143 directly recognize the 3'-untranslated region of KRAS transcripts 10352 hsa-mir-189 Tourette Syndrome 16224024 Sequence variants in SLITRK1 are associated with Tourette's syndrome. 10353 hsa-mir-206 Breast Neoplasms 17312270 The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines. 10354 hsa-mir-15a Prostatic Neoplasms 18931683 The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. 10355 hsa-mir-15a Prostatic Neoplasms 18931683 The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. 10356 hsa-mir-16-1 Prostatic Neoplasms 18931683 The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. 10357 hsa-mir-16-1 Prostatic Neoplasms 18931683 The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. 10358 hsa-mir-18a Carcinoma, Squamous Cell 19372139 The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras 10359 hsa-mir-200a Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 10360 hsa-mir-200b Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 10361 hsa-mir-200c Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 10362 hsa-mir-429 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 10363 hsa-mir-141 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 10364 hsa-mir-205 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 10365 hsa-mir-200a Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 10366 hsa-mir-200b Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 10367 hsa-mir-200c Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 10368 hsa-mir-429 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 10369 hsa-mir-141 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 10370 hsa-mir-205 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 10371 hsa-mir-34a Neuroblastoma 18504438 The MYCN oncogene is a direct target of miR-34a. 10372 hsa-mir-126 Colon Neoplasms 18663744 The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers. 10373 hsa-mir-27a Breast Neoplasms 18006846 The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. 10374 hsa-mir-27a Breast Neoplasms 18006846 The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. 10375 hsa-mir-16-1 Lymphoma, Mantle-Cell 18483394 Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma. 10376 hsa-mir-155 Pancreatic Neoplasms 17911264 Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development. 10377 hsa-mir-16-1 Breast Neoplasms 19250063 Two new miR-16 targets: Caprin-1 and HMGA1, proteins implicated in cell proliferation 10378 hsa-mir-16-1 Breast Neoplasms 19250063 Two new miR-16 targets: Caprin-1 and HMGA1, proteins implicated in cell proliferation 10379 hsa-mir-16-2 Breast Neoplasms 19250063 Two new miR-16 targets: Caprin-1 and HMGA1, proteins implicated in cell proliferation 10380 hsa-mir-16-2 Breast Neoplasms 19250063 Two new miR-16 targets: Caprin-1 and HMGA1, proteins implicated in cell proliferation 10381 hsa-mir-433 Parkinson Disease 18252210 Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein.