category mir disease pmid description circulation_biomarker_diagnosis_down hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 15737576 Some human miRNAs are linked to leukemias: the miR-15a/miR-16 locus is frequently deleted or down-regulated in patients with B-cell chronic lymphocytic leukemia and miR-142 is at a translocation site found in a case of aggressive B-cell leukemia. circulation_biomarker_diagnosis_down hsa-mir-16 "Leukemia, Lymphocytic, Chronic, B-Cell" 15737576 Some human miRNAs are linked to leukemias: the miR-15a/miR-16 locus is frequently deleted or down-regulated in patients with B-cell chronic lymphocytic leukemia and miR-142 is at a translocation site found in a case of aggressive B-cell leukemia. circulation_biomarker_diagnosis_down hsa-mir-143 Colon Neoplasms 16195701 downregulation circulation_biomarker_diagnosis_down hsa-mir-145 Colon Neoplasms 16195701 downregulation circulation_biomarker_diagnosis_down hsa-mir-223 "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 downregulated circulation_biomarker_diagnosis_down hsa-mir-29a "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 downregulated circulation_biomarker_diagnosis_down hsa-mir-29c "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 downregulated circulation_biomarker_diagnosis_down hsa-mir-10b Breast Neoplasms 16466964 down-regulated circulation_biomarker_diagnosis_down hsa-mir-125b-1 Breast Neoplasms 16466964 down-regulated circulation_biomarker_diagnosis_down hsa-mir-125b-2 Breast Neoplasms 16466964 down-regulated circulation_biomarker_diagnosis_down hsa-mir-145 Breast Neoplasms 16466964 down-regulated circulation_biomarker_diagnosis_down hsa-mir-106 Leukemia 16549775 "we performed microRNA expression profiling of in vitro-differentiated megakaryocytes derived from CD34(+) hematopoietic progenitors. The main finding was down-regulation of miR-10a, miR-126, miR-106, miR-10b, miR-17 and miR-20." circulation_biomarker_diagnosis_down hsa-mir-10a Leukemia 16549775 "we performed microRNA expression profiling of in vitro-differentiated megakaryocytes derived from CD34(+) hematopoietic progenitors. The main finding was down-regulation of miR-10a, miR-126, miR-106, miR-10b, miR-17 and miR-20." circulation_biomarker_diagnosis_down hsa-mir-10b Leukemia 16549775 "we performed microRNA expression profiling of in vitro-differentiated megakaryocytes derived from CD34(+) hematopoietic progenitors. The main finding was down-regulation of miR-10a, miR-126, miR-106, miR-10b, miR-17 and miR-20." circulation_biomarker_diagnosis_down hsa-mir-126 Leukemia 16549775 "we performed microRNA expression profiling of in vitro-differentiated megakaryocytes derived from CD34(+) hematopoietic progenitors. The main finding was down-regulation of miR-10a, miR-126, miR-106, miR-10b, miR-17 and miR-20." circulation_biomarker_diagnosis_down hsa-mir-17 Leukemia 16549775 "we performed microRNA expression profiling of in vitro-differentiated megakaryocytes derived from CD34(+) hematopoietic progenitors. The main finding was down-regulation of miR-10a, miR-126, miR-106, miR-10b, miR-17 and miR-20." circulation_biomarker_diagnosis_down hsa-mir-20 Leukemia 16549775 "we performed microRNA expression profiling of in vitro-differentiated megakaryocytes derived from CD34(+) hematopoietic progenitors. The main finding was down-regulation of miR-10a, miR-126, miR-106, miR-10b, miR-17 and miR-20." circulation_biomarker_diagnosis_down hsa-let-7a-1 Lung Neoplasms 16712479 downregulation circulation_biomarker_diagnosis_down hsa-let-7a-2 Lung Neoplasms 16712479 downregulation circulation_biomarker_diagnosis_down hsa-let-7a-3 Lung Neoplasms 16712479 downregulation circulation_biomarker_diagnosis_down hsa-let-7b Lung Neoplasms 16712479 downregulation circulation_biomarker_diagnosis_down hsa-let-7c Lung Neoplasms 16712479 downregulation circulation_biomarker_diagnosis_down hsa-let-7d Lung Neoplasms 16712479 downregulation circulation_biomarker_diagnosis_down hsa-let-7e Lung Neoplasms 16712479 downregulation circulation_biomarker_diagnosis_down hsa-let-7f-1 Lung Neoplasms 16712479 downregulation circulation_biomarker_diagnosis_down hsa-let-7f-2 Lung Neoplasms 16712479 downregulation circulation_biomarker_diagnosis_down hsa-let-7g Lung Neoplasms 16712479 downregulation circulation_biomarker_diagnosis_down hsa-let-7i Lung Neoplasms 16712479 downregulation circulation_biomarker_diagnosis_down hsa-mir-143 Colorectal Carcinoma 16847880 reduced circulation_biomarker_diagnosis_down hsa-mir-145 Colorectal Carcinoma 16847880 reduced circulation_biomarker_diagnosis_down hsa-mir-181a-2 "Leukemia, Promyelocytic, Acute" 16847880 miR-181 expression is decreased inTPA-induced differentiation of human promyelocytic leukemia cells. circulation_biomarker_diagnosis_down hsa-mir-181b-1 "Leukemia, Promyelocytic, Acute" 16847880 miR-181 expression is decreased inTPA-induced differentiation of human promyelocytic leukemia cells. circulation_biomarker_diagnosis_down hsa-mir-181b-2 "Leukemia, Promyelocytic, Acute" 16847880 miR-181 expression is decreased inTPA-induced differentiation of human promyelocytic leukemia cells. circulation_biomarker_diagnosis_down hsa-mir-181d "Leukemia, Promyelocytic, Acute" 16847880 miR-181 expression is decreased inTPA-induced differentiation of human promyelocytic leukemia cells. circulation_biomarker_diagnosis_down hsa-mir-143 Colon Neoplasms 16885332 miR-143 and miR-145 expression is reduced. circulation_biomarker_diagnosis_down hsa-mir-145 Breast Neoplasms 16885332 Reduced expression in breast cancers circulation_biomarker_diagnosis_down hsa-mir-155 Neoplasms [unspecific] 16885332 "High expression of precursor miR-155/BIC in pediatric BL, but lack of BIC and miR-155 expression in adult BL" circulation_biomarker_diagnosis_down hsa-mir-143 Colon Neoplasms 16940181 Downregulation of Mir-143 and Mir-145 has been observed in colorectal cancer. circulation_biomarker_diagnosis_down hsa-mir-145 Colon Neoplasms 16940181 Downregulation of Mir-143 and Mir-145 has beenobserved in colorectal cancer. circulation_biomarker_diagnosis_down hsa-mir-15a Pituitary Neoplasms 17028302 Downregulation of miR-15 and miR-16 miRNAs also appears to be a feature of pituitary adenomas. circulation_biomarker_diagnosis_down hsa-mir-15b Pituitary Neoplasms 17028302 Downregulation of miR-15 and miR-16 miRNAs also appears to be a feature of pituitary adenomas. circulation_biomarker_diagnosis_down hsa-mir-16-1 Pituitary Neoplasms 17028302 Downregulation of miR-15 and miR-16 miRNAs also appears to be a feature of pituitary adenomas. circulation_biomarker_diagnosis_down hsa-mir-16-2 Pituitary Neoplasms 17028302 Downregulation of miR-15 and miR-16 miRNAs also appears to be a feature of pituitary adenomas. circulation_biomarker_diagnosis_down hsa-let-7a-1 Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. circulation_biomarker_diagnosis_down hsa-let-7a-2 Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. circulation_biomarker_diagnosis_down hsa-let-7a-3 Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. circulation_biomarker_diagnosis_down hsa-let-7b Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. circulation_biomarker_diagnosis_down hsa-let-7c Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. circulation_biomarker_diagnosis_down hsa-let-7d Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. circulation_biomarker_diagnosis_down hsa-let-7e Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. circulation_biomarker_diagnosis_down hsa-let-7f-1 Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. circulation_biomarker_diagnosis_down hsa-let-7f-2 Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. circulation_biomarker_diagnosis_down hsa-let-7g Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. circulation_biomarker_diagnosis_down hsa-let-7i Lung Neoplasms 17096367 Recent study demonstrated that the expression of let-7 was significantly reduced while the expression of RAS was dramatically increased in lung tumor tissues. circulation_biomarker_diagnosis_down hsa-let-7e "Carcinoma, Hepatocellular" 17188425 "Independent observations showed that the expression of miRNAs let-7e, 125a and 99b, located at 19q13.4, were considerably lower in HCC compared to nontumor liver [59] and [65]. Given that miRNA-125a targets expression of the mitochondrial tumor suppressor gene, MTSG1, and RAR|§Ú§Ó, chromosomal instability in and around FRA19A may extinguish expression of these tumor suppressor genes." circulation_biomarker_diagnosis_down hsa-mir-125a "Carcinoma, Hepatocellular" 17188425 "Independent observations showed that the expression of miRNAs let-7e, 125a and 99b, located at 19q13.4, were considerably lower in HCC compared to nontumor liver [59] and [65]. Given that miRNA-125a targets expression of the mitochondrial tumor suppressor gene, MTSG1, and RAR|§Ú§Ó, chromosomal instability in and around FRA19A may extinguish expression of these tumor suppressor genes." circulation_biomarker_diagnosis_down hsa-mir-99b "Carcinoma, Hepatocellular" 17188425 "Independent observations showed that the expression of miRNAs let-7e, 125a and 99b, located at 19q13.4, were considerably lower in HCC compared to nontumor liver [59] and [65]. Given that miRNA-125a targets expression of the mitochondrial tumor suppressor gene, MTSG1, and RAR|§Ú§Ó, chromosomal instability in and around FRA19A may extinguish expression of these tumor suppressor genes." circulation_biomarker_diagnosis_down hsa-mir-1-1 "Cardiomyopathy, Hypertrophic" 17234972 "Significantly,the muscle-specific microRNA-1 (miR-1) was singularly downregulatedas early as day 1, persisting through day7, after aortic constriction Cinduced hypertrophy in a mouse model." circulation_biomarker_diagnosis_down hsa-mir-1-2 "Cardiomyopathy, Hypertrophic" 17234972 "Significantly,the muscle-specific microRNA-1 (miR-1) was singularly downregulatedas early as day 1, persisting through day7, after aortic constriction Cinduced hypertrophy in a mouse model." circulation_biomarker_diagnosis_down hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 17327404 "Both approaches show that miR-21 and miR-155 are dramatically overexpressed in patients with CLL, although the corresponding genomic loci are not amplified. miR-150 and miR-92 are also significantly deregulated in patients with CLL. In addition, we detected a marked miR-15a and miR-16 decrease in about 11% of cases" circulation_biomarker_diagnosis_down hsa-mir-16 "Leukemia, Lymphocytic, Chronic, B-Cell" 17327404 "Both approaches show that miR-21 and miR-155 are dramatically overexpressed in patients with CLL, although the corresponding genomic loci are not amplified. miR-150 and miR-92 are also significantly deregulated in patients with CLL. In addition, we detected a marked miR-15a and miR-16 decrease in about 11% of cases" circulation_biomarker_diagnosis_down hsa-mir-127 Thyroid Neoplasms 17355635 "three miRNAs showed significantly more underexpression compared to the other downregulated miRNAs. These miRNAs are as follows mir-127, mir-130a and mir-144." circulation_biomarker_diagnosis_down hsa-mir-130a Thyroid Neoplasms 17355635 "three miRNAs showed significantly more underexpression compared to the other downregulated miRNAs. These miRNAs are as follows mir-127, mir-130a and mir-144." circulation_biomarker_diagnosis_down hsa-mir-144 Thyroid Neoplasms 17355635 "three miRNAs showed significantly more underexpression compared to the other downregulated miRNAs. These miRNAs are as follows mir-127, mir-130a and mir-144." circulation_biomarker_diagnosis_down hsa-mir-17 Breast Neoplasms 17442096 "In breast cancer cells, mir-17-5p expression is decreased." circulation_biomarker_diagnosis_down hsa-mir-1-1 "Cardiomyopathy, Hypertrophic" 17468766 downregulation circulation_biomarker_diagnosis_down hsa-mir-1-2 "Cardiomyopathy, Hypertrophic" 17468766 downregulation circulation_biomarker_diagnosis_down hsa-mir-133a-1 "Cardiomyopathy, Hypertrophic" 17468766 downregulation circulation_biomarker_diagnosis_down hsa-mir-133a-2 "Cardiomyopathy, Hypertrophic" 17468766 downregulation circulation_biomarker_diagnosis_down hsa-mir-1-1 "Cardiomyopathy, Hypertrophic" 17479098 "The researchers showed that expression of miR-1 and another muscle-specific miRNA, miR-133, is decreased in human and mouse hypertrophic heart tissue." circulation_biomarker_diagnosis_down hsa-mir-1-2 "Cardiomyopathy, Hypertrophic" 17479098 "The researchers showed that expression of miR-1 and another muscle-specific miRNA, miR-133, is decreased in human and mouse hypertrophic heart tissue." circulation_biomarker_diagnosis_down hsa-mir-133a-1 "Cardiomyopathy, Hypertrophic" 17479098 "The researchers showed that expression of miR-1 and another muscle-specific miRNA, miR-133, is decreased in human and mouse hypertrophic heart tissue." circulation_biomarker_diagnosis_down hsa-mir-133a-2 "Cardiomyopathy, Hypertrophic" 17479098 "The researchers showed that expression of miR-1 and another muscle-specific miRNA, miR-133, is decreased in human and mouse hypertrophic heart tissue." circulation_biomarker_diagnosis_down hsa-mir-148a Asthma 17847008 "Previously, we identified HLA-G as an asthma-susceptibility gene and discovered that the risk of asthma in a child was determined by both the child's HLA-G genotype and the mother's affection status. The activity of pluc-HLAG-G in the presence of each of the three miRNAs was significantly lower than those of pluc-HLAG-C and pluc-HLA-G-Del." circulation_biomarker_diagnosis_down hsa-mir-148b Asthma 17847008 "Previously, we identified HLA-G as an asthma-susceptibility gene and discovered that the risk of asthma in a child was determined by both the child's HLA-G genotype and the mother's affection status. The activity of pluc-HLAG-G in the presence of each of the three miRNAs was significantly lower than those of pluc-HLAG-C and pluc-HLA-G-Del." circulation_biomarker_diagnosis_down hsa-mir-152 Asthma 17847008 "Previously, we identified HLA-G as an asthma-susceptibility gene and discovered that the risk of asthma in a child was determined by both the child's HLA-G genotype and the mother's affection status. The activity of pluc-HLAG-G in the presence of each of the three miRNAs was significantly lower than those of pluc-HLAG-C and pluc-HLA-G-Del." circulation_biomarker_diagnosis_down hsa-mir-143 "Lymphoma, B-Cell" 17892514 Downregulation of microRNAs-143 and -145 in B-cell malignancies. circulation_biomarker_diagnosis_down hsa-mir-143 Breast Neoplasms 17940623 "Studies have implicated other miRNAs in tumorigenesis. MiR-143 and miR-145, for instance, have been shown to be constantly down-regulated in colorectal tumors, and recent studies by Croce et al. also have shown that the downregulation of these miRNAs is a common occurrence in breast carcinomas and breast cancer lines." circulation_biomarker_diagnosis_down hsa-mir-143 Colon Neoplasms 17940623 "Studies have implicated other miRNAs in tumorigenesis. MiR-143 and miR-145, for instance, have been shown to be constantly down-regulated in colorectal tumors, and recent studies by Croce et al. also have shown that the downregulation of these miRNAs is a common occurrence in breast carcinomas and breast cancer lines." circulation_biomarker_diagnosis_down hsa-mir-145 Breast Neoplasms 17940623 "Studies have implicated other miRNAs in tumorigenesis. MiR-143 and miR-145, for instance, have been shown to be constantly down-regulated in colorectal tumors, and recent studies by Croce et al. also have shown that the downregulation of these miRNAs is a common occurrence in breast carcinomas and breast cancer lines." circulation_biomarker_diagnosis_down hsa-mir-145 Colon Neoplasms 17940623 "Studies have implicated other miRNAs in tumorigenesis. MiR-143 and miR-145, for instance, have been shown to be constantly down-regulated in colorectal tumors, and recent studies by Croce et al. also have shown that the downregulation of these miRNAs is a common occurrence in breast carcinomas and breast cancer lines." circulation_biomarker_diagnosis_down hsa-mir-17 Breast Neoplasms 17965831 "miR-17-5p was down-regulated in breast cancer cells, and enhanced expression decreased tumour cell proliferation." circulation_biomarker_diagnosis_down hsa-let-7a-3 Ovarian Neoplasms 17974952 decreased circulation_biomarker_diagnosis_down hsa-mir-150 Polycythemia Vera 17976518 "Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11." circulation_biomarker_diagnosis_down hsa-mir-155 Polycythemia Vera 17976518 "Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11." circulation_biomarker_diagnosis_down hsa-mir-221 Polycythemia Vera 17976518 "Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11." circulation_biomarker_diagnosis_down hsa-let-7b "Leukemia, Myeloid, Acute" 18056805 "Among them, miR-128a and -128b are significantly overexpressed, whereas let-7b and miR-223 are significantly down-regulated in ALL compared with AML." circulation_biomarker_diagnosis_down hsa-mir-223 "Leukemia, Lymphoblastic" 18056805 "Among them, miR-128a and -128b are significantly overexpressed, whereas let-7b and miR-223 are significantly down-regulated in ALL compared with AML." circulation_biomarker_diagnosis_down hsa-mir-128-1 "Lymphoma, Hodgkin" 18089852 down-regulated circulation_biomarker_diagnosis_down hsa-mir-128-2 "Lymphoma, Hodgkin" 18089852 down-regulated circulation_biomarker_diagnosis_down hsa-mir-96 "Lymphoma, Hodgkin" 18089852 down-regulated circulation_biomarker_diagnosis_down hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 18362358 lost or downregulated circulation_biomarker_diagnosis_down hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 18362358 lost or downregulated circulation_biomarker_diagnosis_down hsa-mir-29c Nasopharyngeal Neoplasms 18390668 down-regulated circulation_biomarker_diagnosis_down hsa-mir-199a-1 Neoplasms [unspecific] 18430245 decreased circulation_biomarker_diagnosis_down hsa-let-7a Polycythemia Vera 18508790 "We observed down-regulation of let-7a and up-regulation of miR-182 in polycythemia vera granulocytes, up-regulation of miR-143, miR-145 and miR-223 in polycythemia vera mononuclear cells, up-regulation of miR-26b in polycythemia vera platelets, and down-regulation of miR-30b, miR-30c and miR-150 in polycythemia vera reticulocytes." circulation_biomarker_diagnosis_down hsa-mir-150 Polycythemia Vera 18508790 "We observed down-regulation of let-7a and up-regulation of miR-182 in polycythemia vera granulocytes, up-regulation of miR-143, miR-145 and miR-223 in polycythemia vera mononuclear cells, up-regulation of miR-26b in polycythemia vera platelets, and down-regulation of miR-30b, miR-30c and miR-150 in polycythemia vera reticulocytes." circulation_biomarker_diagnosis_down hsa-mir-30b Polycythemia Vera 18508790 "We observed down-regulation of let-7a and up-regulation of miR-182 in polycythemia vera granulocytes, up-regulation of miR-143, miR-145 and miR-223 in polycythemia vera mononuclear cells, up-regulation of miR-26b in polycythemia vera platelets, and down-regulation of miR-30b, miR-30c and miR-150 in polycythemia vera reticulocytes." circulation_biomarker_diagnosis_down hsa-mir-30c Polycythemia Vera 18508790 "We observed down-regulation of let-7a and up-regulation of miR-182 in polycythemia vera granulocytes, up-regulation of miR-143, miR-145 and miR-223 in polycythemia vera mononuclear cells, up-regulation of miR-26b in polycythemia vera platelets, and down-regulation of miR-30b, miR-30c and miR-150 in polycythemia vera reticulocytes." circulation_biomarker_diagnosis_down hsa-mir-222 Breast Neoplasms 18777135 miR-222: decreased expression in c-Myc induced mouse mammary tumors circulation_biomarker_diagnosis_down hsa-let-7e Ovarian Neoplasms 18823650 let-7e: deregulated circulation_biomarker_diagnosis_down hsa-mir-182 Retinal Degeneration 18834879 miR-182: decreased expression circulation_biomarker_diagnosis_down hsa-mir-183 Retinal Degeneration 18834879 miR-183: decreased expression circulation_biomarker_diagnosis_down hsa-mir-96 Retinal Degeneration 18834879 miR-96: decreased expression circulation_biomarker_diagnosis_down hsa-mir-141 "Carcinoma, Renal Cell" 18925646 miR-141: down-regulation circulation_biomarker_diagnosis_down hsa-mir-200c "Carcinoma, Renal Cell" 18925646 miR-200c: down-regulation circulation_biomarker_diagnosis_down hsa-mir-125b-1 Myelodysplastic Syndromes 18936236 miR-125b-1: Myeloid cell differentiation arrest by miR-125b-1 circulation_biomarker_diagnosis_down hsa-mir-17 "Lymphoma, B-Cell" 18941111 miR-17: down-regulates expression of distinct targets circulation_biomarker_diagnosis_down hsa-mir-18a "Lymphoma, B-Cell" 18941111 miR-18a: down-regulates expression of distinct targets circulation_biomarker_diagnosis_down hsa-mir-19a "Lymphoma, B-Cell" 18941111 miR-19a: down-regulates expression of distinct targets circulation_biomarker_diagnosis_down hsa-mir-19b-1 "Lymphoma, B-Cell" 18941111 miR-19b: down-regulates expression of distinct targets circulation_biomarker_diagnosis_down hsa-mir-19b-2 "Lymphoma, B-Cell" 18941111 miR-19b: down-regulates expression of distinct targets circulation_biomarker_diagnosis_down hsa-mir-20a "Lymphoma, B-Cell" 18941111 miR-20a: down-regulates expression of distinct targets circulation_biomarker_diagnosis_down hsa-mir-92a-1 "Lymphoma, B-Cell" 18941111 miR-92a: down-regulates expression of distinct targets circulation_biomarker_diagnosis_down hsa-mir-92a-2 "Lymphoma, B-Cell" 18941111 miR-92a: down-regulates expression of distinct targets circulation_biomarker_diagnosis_down hsa-mir-127 "Carcinoma, Hepatocellular" 18942116 miR-127: Down-regulation during hepatocarcinogenesis induced by a methyl-deficient diet circulation_biomarker_diagnosis_down hsa-mir-200b "Carcinoma, Hepatocellular" 18942116 miR-200b: Down-regulation during hepatocarcinogenesis induced by a methyl-deficient diet circulation_biomarker_diagnosis_down hsa-mir-34a "Carcinoma, Hepatocellular" 18942116 miR-34a: Down-regulation during hepatocarcinogenesis induced by a methyl-deficient diet circulation_biomarker_diagnosis_down hsa-mir-337 Neurodegenerative Diseases [unspecific] 18987751 miR-337-3p: down-regulated circulation_biomarker_diagnosis_down hsa-mir-338 Neurodegenerative Diseases [unspecific] 18987751 miR-338-3p: down-regulated circulation_biomarker_diagnosis_down hsa-mir-150 Lupus Vulgaris 18998140 miR-150: downregulation circulation_biomarker_diagnosis_down hsa-mir-210 Lupus Vulgaris 18998140 miR-210: downregulation circulation_biomarker_diagnosis_down hsa-mir-223 Lupus Vulgaris 18998140 miR-223: downregulation circulation_biomarker_diagnosis_down hsa-mir-296 Lupus Vulgaris 18998140 miR-296: downregulation circulation_biomarker_diagnosis_down hsa-mir-30d Lupus Vulgaris 18998140 miR-30d: downregulation circulation_biomarker_diagnosis_down hsa-mir-324 Lupus Vulgaris 18998140 miR-324-3p: downregulation circulation_biomarker_diagnosis_down hsa-mir-346 Lupus Vulgaris 18998140 miR-346: downregulation circulation_biomarker_diagnosis_down hsa-mir-365a Lupus Vulgaris 18998140 miR-365: downregulation circulation_biomarker_diagnosis_down hsa-mir-365b Lupus Vulgaris 18998140 miR-365: downregulation circulation_biomarker_diagnosis_down hsa-mir-423 Lupus Vulgaris 18998140 miR-423: downregulation circulation_biomarker_diagnosis_down hsa-mir-484 Lupus Vulgaris 18998140 miR-484: downregulation circulation_biomarker_diagnosis_down hsa-mir-486 Lupus Vulgaris 18998140 miR-486: downregulation circulation_biomarker_diagnosis_down hsa-mir-500a Lupus Vulgaris 18998140 miR-500: downregulation circulation_biomarker_diagnosis_down hsa-mir-518b Lupus Vulgaris 18998140 miR-518b: downregulation circulation_biomarker_diagnosis_down hsa-mir-557 Lupus Vulgaris 18998140 miR-557: downregulation circulation_biomarker_diagnosis_down hsa-mir-596 Lupus Vulgaris 18998140 miR-596: downregulation circulation_biomarker_diagnosis_down hsa-mir-602 Lupus Vulgaris 18998140 miR-602: downregulation circulation_biomarker_diagnosis_down hsa-mir-611 Lupus Vulgaris 18998140 miR-611: downregulation circulation_biomarker_diagnosis_down hsa-mir-615 Lupus Vulgaris 18998140 miR-615: downregulation circulation_biomarker_diagnosis_down hsa-mir-629 Lupus Vulgaris 18998140 miR-629: downregulation circulation_biomarker_diagnosis_down hsa-mir-637 Lupus Vulgaris 18998140 miR-637: downregulation circulation_biomarker_diagnosis_down hsa-mir-642a Lupus Vulgaris 18998140 miR-642: downregulation circulation_biomarker_diagnosis_down hsa-mir-654 Lupus Vulgaris 18998140 miR-654: downregulation circulation_biomarker_diagnosis_down hsa-mir-663a Lupus Vulgaris 18998140 miR-663: downregulation circulation_biomarker_diagnosis_down hsa-mir-769 Lupus Vulgaris 18998140 miR-769-3p: downregulation circulation_biomarker_diagnosis_down hsa-mir-99a Lupus Vulgaris 18998140 miR-99a: downregulation circulation_biomarker_diagnosis_down hsa-mir-181a-2 Leukemia 19022373 miR-181a*: downregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal circulation_biomarker_diagnosis_down hsa-mir-199b Leukemia 19022373 miR-199b: downregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal circulation_biomarker_diagnosis_down hsa-mir-378a Leukemia 19022373 miR-378: downregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal circulation_biomarker_diagnosis_down hsa-mir-454 Leukemia 19022373 miR-454-3p: downregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal circulation_biomarker_diagnosis_down hsa-mir-575 Leukemia 19022373 miR-575: downregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal circulation_biomarker_diagnosis_down hsa-mir-10a "Leukemia, Myeloid, Chronic-Phase" 19074828 miR-10a: Down-regulation of hsa-miR-10a in chronic myeloid leukemia CD34+ cells increases USF2-mediated cell growth circulation_biomarker_diagnosis_down hsa-mir-22 "Leukemia, Lymphocytic, Chronic, B-Cell" 19144983 miR-22: downregulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification circulation_biomarker_diagnosis_down hsa-mir-29c "Leukemia, Lymphocytic, Chronic, B-Cell" 19144983 miR-29c: downregulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification circulation_biomarker_diagnosis_down hsa-mir-373 "Leukemia-Lymphoma, Precursor B-Cell Lymphoblastic" 19206004 miR-373*: down-regulated circulation_biomarker_diagnosis_down hsa-mir-451a "Leukemia-Lymphoma, Precursor B-Cell Lymphoblastic" 19206004 miR-451: down-regulated circulation_biomarker_diagnosis_down hsa-mir-143 Colorectal Carcinoma 19242066 miR-143: only down-regulated in colon cancer but not in rectal cancer circulation_biomarker_diagnosis_down hsa-mir-145 Colorectal Carcinoma 19242066 miR-145: down-regulated in both colon and rectal cancer circulation_biomarker_diagnosis_down hsa-mir-346 Schizophrenia 19264453 miR-346: Expression of both miR-346 and GRID1 is lower in SZ patients than that in normal controls circulation_biomarker_diagnosis_down hsa-mir-150 Marek Disease 19297609 miR-150: down-regulated circulation_biomarker_diagnosis_down hsa-mir-223 Marek Disease 19297609 miR-223: down-regulated circulation_biomarker_diagnosis_down hsa-mir-363 Autistic Disorder 19360674 miR-363: downregulated circulation_biomarker_diagnosis_down hsa-mir-92a-1 Autistic Disorder 19360674 miR-92a-1: downregulated circulation_biomarker_diagnosis_down hsa-mir-92a-2 Autistic Disorder 19360674 miR-92a-2: downregulated circulation_biomarker_diagnosis_down hsa-mir-181b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 "low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion" circulation_biomarker_diagnosis_down hsa-mir-181b-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 "low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion" circulation_biomarker_diagnosis_down hsa-mir-181c "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 "low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion" circulation_biomarker_diagnosis_down hsa-mir-223 "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 "low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion" circulation_biomarker_diagnosis_down hsa-mir-29b-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 "low expression of the miR-223, miR-29c, miR-29b, and miR-181 family were strongly associated with disease progression in CLL cases harboring 17p deletion" circulation_biomarker_diagnosis_down hsa-mir-145 Atherosclerosis 19744308 downregulated circulation_biomarker_diagnosis_down hsa-mir-150 Sepsis 19823581 miR-150 as a plasma prognostic marker in patients with sepsis circulation_biomarker_diagnosis_down hsa-mir-199b Choriocarcinoma 19900756 miR-199b:Decreased expression of microRNA-199b increases protein levels of SET (protein phosphatase 2A inhibitor) in human choriocarcinoma circulation_biomarker_diagnosis_down hsa-mir-146a Sepsis 20188071 Serum miR-146a and miR-223 as potential new biomarkers for sepsis circulation_biomarker_diagnosis_down hsa-mir-223 Sepsis 20188071 Serum miR-146a and miR-223 as potential new biomarkers for sepsis circulation_biomarker_diagnosis_down hsa-mir-200a Glomerulonephritis 20364043 down-regulated circulation_biomarker_diagnosis_down hsa-mir-200b Glomerulonephritis 20364043 down-regulated circulation_biomarker_diagnosis_down hsa-mir-429 Glomerulonephritis 20364043 down-regulated circulation_biomarker_diagnosis_down hsa-mir-106b "Child Development Disorders, Pervasive" 20374639 down-regulation circulation_biomarker_diagnosis_down hsa-mir-181b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 20393129 "miR-181b:We found that miR-15a, miR-21, miR-34a, miR-155, and miR-181b were differentially expressed between CLLs with chromosome 17p deletion and CLLs with normal 17p and normal karyotype, and that miR-181b was down-regulated in therapy-refractory cases" circulation_biomarker_diagnosis_down hsa-mir-181b-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 20393129 "miR-181b:We found that miR-15a, miR-21, miR-34a, miR-155, and miR-181b were differentially expressed between CLLs with chromosome 17p deletion and CLLs with normal 17p and normal karyotype, and that miR-181b was down-regulated in therapy-refractory cases" circulation_biomarker_diagnosis_down hsa-let-7i Melanoma 20529253 let-7i*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-106b Melanoma 20529253 miR-106b:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-107 Melanoma 20529253 miR-107:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-17 Melanoma 20529253 miR-17:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-20a Melanoma 20529253 miR-20a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-20b Melanoma 20529253 miR-20b:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-214 Melanoma 20529253 miR-214:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-216a Melanoma 20529253 miR-216a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-217 Melanoma 20529253 miR-217:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-221 Melanoma 20529253 miR-221*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-330 Melanoma 20529253 miR-330-3p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-452 Melanoma 20529253 miR-452:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-509-3 Melanoma 20529253 miR-509-3-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-517a Melanoma 20529253 miR-517*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-518e Melanoma 20529253 miR-518e*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-519b Melanoma 20529253 miR-519b-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-593 Melanoma 20529253 miR-593*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-621 Melanoma 20529253 miR-621:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-646 Melanoma 20529253 miR-646:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-767 Melanoma 20529253 miR-767-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_down hsa-mir-126 "Diabetes Mellitus, Type 2" 20651284 decreased in plasma circulation_biomarker_diagnosis_down hsa-mir-15a "Diabetes Mellitus, Type 2" 20651284 decreased in plasma circulation_biomarker_diagnosis_down hsa-mir-191 "Diabetes Mellitus, Type 2" 20651284 decreased in plasma circulation_biomarker_diagnosis_down hsa-mir-197 "Diabetes Mellitus, Type 2" 20651284 decreased in plasma circulation_biomarker_diagnosis_down hsa-mir-20b "Diabetes Mellitus, Type 2" 20651284 decreased in plasma circulation_biomarker_diagnosis_down hsa-mir-21 "Diabetes Mellitus, Type 2" 20651284 decreased in plasma circulation_biomarker_diagnosis_down hsa-mir-223 "Diabetes Mellitus, Type 2" 20651284 decreased in plasma circulation_biomarker_diagnosis_down hsa-mir-24-1 "Diabetes Mellitus, Type 2" 20651284 decreased in plasma circulation_biomarker_diagnosis_down hsa-mir-24-2 "Diabetes Mellitus, Type 2" 20651284 decreased in plasma circulation_biomarker_diagnosis_down hsa-mir-320a "Diabetes Mellitus, Type 2" 20651284 decreased in plasma circulation_biomarker_diagnosis_down hsa-mir-486 "Diabetes Mellitus, Type 2" 20651284 decreased in plasma circulation_biomarker_diagnosis_down hsa-mir-101-1 "Lymphoma, Large-Cell, Anaplastic" 20805506 miR-101:miR-101 was down-regulated in all ALCL model systems circulation_biomarker_diagnosis_down hsa-mir-101-2 "Lymphoma, Large-Cell, Anaplastic" 20805506 miR-101:miR-101 was down-regulated in all ALCL model systems circulation_biomarker_diagnosis_down hsa-mir-181b-1 Autistic Disorder 20868653 miR-181b:deregulated circulation_biomarker_diagnosis_down hsa-mir-486 Autistic Disorder 20868653 miR-486:deregulated circulation_biomarker_diagnosis_down hsa-mir-27a Leukemia 21070600 Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia. circulation_biomarker_diagnosis_down hsa-mir-331 Leukemia 21070600 Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia. circulation_biomarker_diagnosis_down hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 21130495 Downregulation circulation_biomarker_diagnosis_down hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 21130495 Downregulation circulation_biomarker_diagnosis_down hsa-mir-181a-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 21130495 Downregulation circulation_biomarker_diagnosis_down hsa-mir-181b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 21130495 Downregulation circulation_biomarker_diagnosis_down hsa-mir-181b-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 21130495 Downregulation circulation_biomarker_diagnosis_down hsa-mir-29b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 21130495 Downregulation circulation_biomarker_diagnosis_down hsa-mir-29b-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 21130495 Downregulation circulation_biomarker_diagnosis_down hsa-let-7d Pancreatic Neoplasms 21139804 downregulated circulation_biomarker_diagnosis_down hsa-mir-146a Pancreatic Neoplasms 21139804 downregulated circulation_biomarker_diagnosis_down hsa-mir-126 Heart Failure 21157109 "The plasma concentration of miR-126 was negatively correlated with age and NYHA class, and could be a useful biomarker for heart failure" circulation_biomarker_diagnosis_down hsa-mir-424 Hemangioma 21179471 Down-Regulation of mir-424 Contributes to the Abnormal Angiogenesis via MEK1 and Cyclin E1 in Senile Hemangioma: Its Implications to Therapy. circulation_biomarker_diagnosis_down hsa-mir-503 Diabetes Mellitus 21220732 Deregulation of microRNA-503 Contributes to Diabetes Mellitus-Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia. circulation_biomarker_diagnosis_down hsa-mir-125b-1 Human Immunodeficiency Virus Infection 21224041 "heroin-dependent subjects had significantly lower levels of anti-HIV miRNAs (miRNA-28, 125b, 150, and 382) in peripheral blood mononuclear cells than the healthy subjects" circulation_biomarker_diagnosis_down hsa-mir-125b-2 Human Immunodeficiency Virus Infection 21224041 "heroin-dependent subjects had significantly lower levels of anti-HIV miRNAs (miRNA-28, 125b, 150, and 382) in peripheral blood mononuclear cells than the healthy subjects" circulation_biomarker_diagnosis_down hsa-mir-150 Human Immunodeficiency Virus Infection 21224041 "heroin-dependent subjects had significantly lower levels of anti-HIV miRNAs (miRNA-28, 125b, 150, and 382) in peripheral blood mononuclear cells than the healthy subjects" circulation_biomarker_diagnosis_down hsa-mir-28 Human Immunodeficiency Virus Infection 21224041 "heroin-dependent subjects had significantly lower levels of anti-HIV miRNAs (miRNA-28, 125b, 150, and 382) in peripheral blood mononuclear cells than the healthy subjects" circulation_biomarker_diagnosis_down hsa-mir-382 Human Immunodeficiency Virus Infection 21224041 "heroin-dependent subjects had significantly lower levels of anti-HIV miRNAs (miRNA-28, 125b, 150, and 382) in peripheral blood mononuclear cells than the healthy subjects" circulation_biomarker_diagnosis_down hsa-let-7a-1 "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-let-7a-2 "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-let-7a-3 "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-let-7b "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-let-7c "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-let-7d "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-let-7e "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-let-7f-1 "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-let-7f-2 "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-let-7g "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-let-7i "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-mir-26a-1 "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-mir-26a-2 "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-mir-30c-1 "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-mir-30c-2 "Carcinoma, Renal Cell" 21229250 "let-7 family, miR-30c, miR-26a are decreased in highly aggressive primary metastatic tumours." circulation_biomarker_diagnosis_down hsa-let-7b "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 21242186 "aberrant downregulation of let-7b (~70-fold) in MLL-rearranged acute lymphoblastic leukemia was linked to upregulation of oncoprotein c-Myc (P<0.0001). Resistance to vincristine and daunorubicin was characterized by ~20-fold upregulation of miR-125b, miR-99a and miR-100 (P<0.002)." circulation_biomarker_diagnosis_down hsa-mir-16-1 "Carcinoma, Hepatocellular" 21278583 Serum levels of miR-16 and miR-199a were significantly lower in HCC than in CLD patients or control subjects (P<0.01). circulation_biomarker_diagnosis_down hsa-mir-16-2 "Carcinoma, Hepatocellular" 21278583 Serum levels of miR-16 and miR-199a were significantly lower in HCC than in CLD patients or control subjects (P<0.01). circulation_biomarker_diagnosis_down hsa-mir-199a-1 "Carcinoma, Hepatocellular" 21278583 Serum levels of miR-16 and miR-199a were significantly lower in HCC than in CLD patients or control subjects (P<0.01). circulation_biomarker_diagnosis_down hsa-mir-199a-2 "Carcinoma, Hepatocellular" 21278583 Serum levels of miR-16 and miR-199a were significantly lower in HCC than in CLD patients or control subjects (P<0.01). circulation_biomarker_diagnosis_down hsa-mir-1-1 Hypertrophy 21303526 "The downregulation of miR-1, miR-133a, and upregulation of miR-21 can be reversed by one single upstream regulator, SRF." circulation_biomarker_diagnosis_down hsa-mir-1-2 Hypertrophy 21303526 "The downregulation of miR-1, miR-133a, and upregulation of miR-21 can be reversed by one single upstream regulator, SRF." circulation_biomarker_diagnosis_down hsa-mir-133a-1 Hypertrophy 21303526 "The downregulation of miR-1, miR-133a, and upregulation of miR-21 can be reversed by one single upstream regulator, SRF." circulation_biomarker_diagnosis_down hsa-mir-133a-2 Hypertrophy 21303526 "The downregulation of miR-1, miR-133a, and upregulation of miR-21 can be reversed by one single upstream regulator, SRF." circulation_biomarker_diagnosis_down hsa-mir-101-1 Glioblastoma 21321380 "miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis." circulation_biomarker_diagnosis_down hsa-mir-101-2 Glioblastoma 21321380 "miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis." circulation_biomarker_diagnosis_down hsa-mir-141 Systemic Lupus Erythematosus 21372198 "The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls." circulation_biomarker_diagnosis_down hsa-mir-192 Systemic Lupus Erythematosus 21372198 "The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls." circulation_biomarker_diagnosis_down hsa-mir-200a Systemic Lupus Erythematosus 21372198 "The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls." circulation_biomarker_diagnosis_down hsa-mir-200b Systemic Lupus Erythematosus 21372198 "The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls." circulation_biomarker_diagnosis_down hsa-mir-200c Systemic Lupus Erythematosus 21372198 "The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls." circulation_biomarker_diagnosis_down hsa-mir-205 Systemic Lupus Erythematosus 21372198 "The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls." circulation_biomarker_diagnosis_down hsa-mir-429 Systemic Lupus Erythematosus 21372198 "The serum levels of miR-200a, miR-200b, miR-200c, miR-429, miR-205 and miR-192, and urinary miR-200a, miR-200c, miR-141, miR-429 and miR-192 of SLE patients were lower than those of controls." circulation_biomarker_diagnosis_down hsa-mir-92a-1 Lymphoma 21383985 Down-Regulated Plasma miR-92a Levels in Non-Hodgkin's Lymphoma. circulation_biomarker_diagnosis_down hsa-mir-92a-2 Lymphoma 21383985 Down-Regulated Plasma miR-92a Levels in Non-Hodgkin's Lymphoma. circulation_biomarker_diagnosis_down hsa-mir-103a-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 21408091 downregulation circulation_biomarker_diagnosis_down hsa-mir-103a-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 21408091 downregulation circulation_biomarker_diagnosis_down hsa-mir-181a-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 21408091 downregulation circulation_biomarker_diagnosis_down hsa-mir-181b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 21408091 downregulation circulation_biomarker_diagnosis_down hsa-mir-181b-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 21408091 downregulation circulation_biomarker_diagnosis_down hsa-mir-16-1 "Leukemia-Lymphoma, Adult T-Cell" 21441948 Triptolide inhibits the proliferation of cells from lymphocytic leukemic cell lines in association with downregulation of NF-kB activity and miR-16-1(*). circulation_biomarker_diagnosis_down hsa-mir-100 "Carcinoma, Adrenocortical" 21472710 "miRs -100, -125b, and -195 were significantly down-regulated, whereas miR-483-5p was significantly up-regulated in malignant as compared with benign tumors." circulation_biomarker_diagnosis_down hsa-mir-126 Mesothelioma 21483773 "Levels of miR-126 in serum, and its levels in patients' serum in association with a specific marker of MPM, SMRPs, correlate with subjects at high risk to develop malignant pleural mesothelioma (MPM)." circulation_biomarker_diagnosis_down hsa-mir-451a "Leukemia, Myeloid, Chronic" 21511335 downregulated circulation_biomarker_diagnosis_down hsa-mir-106a "Carcinoma, Lung, Non-Small-Cell" 21544802 "The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased." circulation_biomarker_diagnosis_down hsa-mir-146b "Carcinoma, Lung, Non-Small-Cell" 21544802 "The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased." circulation_biomarker_diagnosis_down hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 21544802 "The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased." circulation_biomarker_diagnosis_down hsa-mir-17 "Carcinoma, Lung, Non-Small-Cell" 21544802 "The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased." circulation_biomarker_diagnosis_down hsa-mir-221 "Carcinoma, Lung, Non-Small-Cell" 21544802 "The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased." circulation_biomarker_diagnosis_down hsa-mir-223 "Carcinoma, Lung, Non-Small-Cell" 21544802 Reduced plasma expression of let-7b was modestly associated with worse cancer-specific mortality in all patients and reduced serum expression of miR-223 was modestly associated with cancer-specific mortality in stage IA/B patients. circulation_biomarker_diagnosis_down hsa-mir-27a "Carcinoma, Lung, Non-Small-Cell" 21544802 "The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased." circulation_biomarker_diagnosis_down hsa-mir-590 Alzheimer Disease 21548758 "Decreased relative expression levels of hsa-miR-590-3p in blood cells was observed in patients with AD versus controls. hnRNP-A1 and its transcription regulatory factor miR-590-3p are disregulated in patients with AD, and the hnRNP-A1 rs7967622 C/C genotype is likely a risk factor for FTLD in male populations." circulation_biomarker_diagnosis_down hsa-mir-342 Glioblastoma 21561454 miR-342-3p: downregulated in the peripheral blood of glioblastoma patients. circulation_biomarker_diagnosis_down hsa-mir-181b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 21636858 MiR-181b is a biomarker of disease progression in chronic lymphocytic leukemia circulation_biomarker_diagnosis_down hsa-mir-181b-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 21636858 MiR-181b is a biomarker of disease progression in chronic lymphocytic leukemia circulation_biomarker_diagnosis_down hsa-mir-671 Myelodysplastic Syndromes 21649547 miR-671-5p: down-regulation circulation_biomarker_diagnosis_down hsa-mir-375 "Squamous Cell Carcinoma, Esophageal" 21673684 "the plasma level of miR-21 was significantly higher (P=0.0218) and that of miR-375 (P=0.0052) was significantly lower in ESCC patients than controls. (2) The high plasma miR-21 levels reflected tumour levels in all cases (100%). The plasma level of miR-21 was significantly reduced in postoperative samples (P=0.0058). (3) On validation analysis, the plasma level of miR-21 tended to be higher in ESCC patients (P=0.0649), while that of miR-375 was significantly lower (P<0.0001) and the miR-21/miR-375 ratio was significantly higher (P<0.0001) in ESCC patients than in controls. The value of the area under the receiver-operating characteristic curve (AUC) was 0.816 for the miR-21/miR-375 ratio assay. Patients with a high plasma level of miR-21 tended to have greater vascular invasion (P=0.1554) and to show a high correlation with recurrence (P=0.0164)." circulation_biomarker_diagnosis_down hsa-mir-143 "Leukemia, Myeloid, Acute" 21678057 miR-29a and miR-142-3p show downregulation and diagnostic implication in human acute myeloid leukemia. circulation_biomarker_diagnosis_down hsa-mir-29a "Leukemia, Myeloid, Acute" 21678057 miR-29a and miR-142-3p show downregulation and diagnostic implication in human acute myeloid leukemia. circulation_biomarker_diagnosis_down hsa-mir-21 "Carcinoma, Hepatocellular" 21749846 "In the 10-patient group, plasma microRNA-21 levels significantly diminished after surgery compared with the pre-operative values (p=0.0125). Plasma microRNA-21 level in the 126 patients with hepatocellular carcinoma was significantly higher than in patients with chronic hepatitis and healthy volunteers (p<0.0001, p<0.0001, respectively). ROC analysis of plasma microRNA-21 yielded an AUC of 0.773 with 61.1% sensitivity and 83.3% specificity when differentiating hepatocellular carcinoma from chronic hepatitis, and an AUC of 0.953 with 87.3% sensitivity and 92.0% specificity when differentiating hepatocellular carcinoma from healthy volunteers." circulation_biomarker_diagnosis_down hsa-mir-29a "Leukemia, Myeloid, Acute" 21818844 "Lower miR-29a expression was mainly observed in MLL-rearranged pediatric acute myeloid leukemia, specifically in cases carrying t(10;11)." circulation_biomarker_diagnosis_down hsa-mir-17 Lymphoma 21910161 "miR-17-5p: Compared with normal canine peripheral blood mononuclear cells (PBMC) and normal lymph nodes (LN), the miRNA show an increased expression level." circulation_biomarker_diagnosis_down hsa-mir-181a-2 Lymphoma 21910161 "Compared with normal canine peripheral blood mononuclear cells (PBMC) and normal lymph nodes (LN), the miRNA show a decreased expression level." circulation_biomarker_diagnosis_down hsa-mir-19a Lymphoma 21910161 "Compared with normal canine peripheral blood mononuclear cells (PBMC) and normal lymph nodes (LN), the miRNA show an increased expression level." circulation_biomarker_diagnosis_down hsa-mir-19b-1 Lymphoma 21910161 "Compared with normal canine peripheral blood mononuclear cells (PBMC) and normal lymph nodes (LN), the miRNA show an increased expression level." circulation_biomarker_diagnosis_down hsa-mir-19b-2 Lymphoma 21910161 "Compared with normal cani ne peripheral blood mononuclear cells (PBMC) and normal lymph nodes (LN), the miRNA show an increased expression level." circulation_biomarker_diagnosis_down hsa-mir-203 Lymphoma 21910161 "Compared with normal canine peripheral blood mononuclear cells (PBMC) and normal lymph nodes (LN), the miRNA show a decreased expression level." circulation_biomarker_diagnosis_down hsa-mir-218-1 Lymphoma 21910161 "Compared with normal canine peripheral blood mononuclear cells (PBMC) and normal lymph nodes (LN), the miRNA show a decreased expression level." circulation_biomarker_diagnosis_down hsa-mir-218-2 Lymphoma 21910161 "Compared with normal canine peripheral blood mononuclear cells (PBMC) and normal lymph nodes (LN), the miRNA show a decreased expression level." circulation_biomarker_diagnosis_down hsa-mir-133b Hypertension 21924071 "MiR-296-5p (Fold change 0.47, P = 0.013) and miR-133b (Fold change 0.57, P = 0.033) were consistently down-regulated in the patient plasma, whereas let-7e (Fold change 1.62, P = 0.009) and hcmv-miR-UL112 (Fold change 2.72, P = 0.004), one human cytomegalovirus encoded microRNAs, were up-regulated in the patient samples." circulation_biomarker_diagnosis_down hsa-mir-296 Hypertension 21924071 "MiR-296-5p (Fold change 0.47, P = 0.013) and miR-133b (Fold change 0.57, P = 0.033) were consistently down-regulated in the patient plasma, whereas let-7e (Fold change 1.62, P = 0.009) and hcmv-miR-UL112 (Fold change 2.72, P = 0.004), one human cytomegalovirus encoded microRNAs, were up-regulated in the patient samples." circulation_biomarker_diagnosis_down hsa-mir-152 Preeclampsia 22095477 Serum expression level of mir-152 was down-regulated in preeclampsia patients. circulation_biomarker_diagnosis_down hsa-mir-218-1 Urinary Bladder Cancer 22237456 Circulating microRNA-218 was reduced in cervical cancer and correlated with tumor invasion. circulation_biomarker_diagnosis_down hsa-mir-218-2 Urinary Bladder Cancer 22237456 Circulating microRNA-218 was reduced in cervical cancer and correlated with tumor invasion. circulation_biomarker_diagnosis_down hsa-mir-107 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-1469 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-1471 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-182 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-1915 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-193a Breast Neoplasms 22242178 miR-193a-3p is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-2355 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-24-1 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-24-2 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-3130-1 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-3130-2 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-3186 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-526a-1 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-526a-2 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-625 Breast Neoplasms 22242178 miR-625* is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-718 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-874 Breast Neoplasms 22242178 The miRNA is down-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_down hsa-mir-181a-2 "Leukemia, Myeloid, Acute" 22251480 Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. circulation_biomarker_diagnosis_down hsa-mir-181b-1 "Leukemia, Myeloid, Acute" 22251480 Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. circulation_biomarker_diagnosis_down hsa-mir-181b-2 "Leukemia, Myeloid, Acute" 22251480 Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. circulation_biomarker_diagnosis_down hsa-mir-181c "Leukemia, Myeloid, Acute" 22251480 Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. circulation_biomarker_diagnosis_down hsa-mir-181d "Leukemia, Myeloid, Acute" 22251480 Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. circulation_biomarker_diagnosis_down hsa-mir-508 "Carcinoma, Renal Cell" 22369946 "Both miR-508-3p and miR-509-3p were down-regulated in renal cancer tissues. The level of miR-508-3p but not miR-509-3p in renal cell carcinoma (RCC) patient plasma demonstrated significant differences from that in control plasma. In addition, the overexpression of miR-508-3p and miR-509-3p suppressed the proliferation of RCC cells (786-0), induced cell apoptosis and inhibited cell migration in vitro." circulation_biomarker_diagnosis_down hsa-mir-509-1 "Carcinoma, Renal Cell" 22369946 "Both miR-508-3p and miR-509-3p were down-regulated in renal cancer tissues. The level of miR-508-3p but not miR-509-3p in renal cell carcinoma (RCC) patient plasma demonstrated significant differences from that in control plasma. In addition, the overexpression of miR-508-3p and miR-509-3p suppressed the proliferation of RCC cells (786-0), induced cell apoptosis and inhibited cell migration in vitro." circulation_biomarker_diagnosis_down hsa-mir-509-2 "Carcinoma, Renal Cell" 22369946 "Both miR-508-3p and miR-509-3p were down-regulated in renal cancer tissues. The level of miR-508-3p but not miR-509-3p in renal cell carcinoma (RCC) patient plasma demonstrated significant differences from that in control plasma. In addition, the overexpression of miR-508-3p and miR-509-3p suppressed the proliferation of RCC cells (786-0), induced cell apoptosis and inhibited cell migration in vitro." circulation_biomarker_diagnosis_down hsa-mir-509-3 "Carcinoma, Renal Cell" 22369946 "Both miR-508-3p and miR-509-3p were down-regulated in renal cancer tissues. The level of miR-508-3p but not miR-509-3p in renal cell carcinoma (RCC) patient plasma demonstrated significant differences from that in control plasma. In addition, the overexpression of miR-508-3p and miR-509-3p suppressed the proliferation of RCC cells (786-0), induced cell apoptosis and inhibited cell migration in vitro." circulation_biomarker_diagnosis_down hsa-mir-126 Mesothelioma 22374169 Kaplan-Meier analysis revealed that low level of circulating miR-126 in MM patients was strongly associated with worse prognosis. circulation_biomarker_diagnosis_down hsa-let-7c Eosinophilic Esophagitis 22391115 downregulated circulation_biomarker_diagnosis_down hsa-mir-144 Eosinophilic Esophagitis 22391115 miR-144*: downregulated circulation_biomarker_diagnosis_down hsa-mir-193a Eosinophilic Esophagitis 22391115 miR-193a-5p and miR-193a-3p: downregulated circulation_biomarker_diagnosis_down hsa-mir-193b Eosinophilic Esophagitis 22391115 downregulated circulation_biomarker_diagnosis_down hsa-mir-203 Eosinophilic Esophagitis 22391115 downregulated circulation_biomarker_diagnosis_down hsa-mir-210 Eosinophilic Esophagitis 22391115 downregulated circulation_biomarker_diagnosis_down hsa-mir-211 Eosinophilic Esophagitis 22391115 downregulated circulation_biomarker_diagnosis_down hsa-mir-30a Eosinophilic Esophagitis 22391115 miR-30a-3p: downregulated circulation_biomarker_diagnosis_down hsa-mir-365a Eosinophilic Esophagitis 22391115 downregulated circulation_biomarker_diagnosis_down hsa-mir-375 Eosinophilic Esophagitis 22391115 "The most downregulated miRNA, which strongly correlated with esophageal eosinophil levels." circulation_biomarker_diagnosis_down hsa-mir-517a Ectopic Pregnancy 22395025 "Concentrations of serum hCG, progesterone, miR-517a, miR-519d, and miR-525-3p were significantly lower in EP and SA cases than in VIP cases. In contrast, the concentration of miR-323-3p was significantly increased in EP cases, compared with SA and VIP cases. As a single marker, miR-323-3p had the highest sensitivity of 37.0% (at a fixed specificity of 90%)." circulation_biomarker_diagnosis_down hsa-mir-519d Ectopic Pregnancy 22395025 "Concentrations of serum hCG, progesterone, miR-517a, miR-519d, and miR-525-3p were significantly lower in EP and SA cases than in VIP cases. In contrast, the concentration of miR-323-3p was significantly increased in EP cases, compared with SA and VIP cases. As a single marker, miR-323-3p had the highest sensitivity of 37.0% (at a fixed specificity of 90%)." circulation_biomarker_diagnosis_down hsa-mir-525 Ectopic Pregnancy 22395025 "Concentrations of serum hCG, progesterone, miR-517a, miR-519d, and miR-525-3p were significantly lower in EP and SA cases than in VIP cases. In contrast, the concentration of miR-323-3p was significantly increased in EP cases, compared with SA and VIP cases. As a single marker, miR-323-3p had the highest sensitivity of 37.0% (at a fixed specificity of 90%)." circulation_biomarker_diagnosis_down hsa-let-7a-1 "Carcinoma, Renal Cell" 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-let-7a-2 "Carcinoma, Renal Cell" 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-let-7a-3 "Carcinoma, Renal Cell" 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-let-7f-1 "Carcinoma, Renal Cell" 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-let-7f-2 "Carcinoma, Renal Cell" 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-mir-142 "Carcinoma, Renal Cell" 22440013 miR-142-5p: Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-mir-150 "Carcinoma, Renal Cell" 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-mir-19a "Carcinoma, Renal Cell" 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-mir-219 "Carcinoma, Renal Cell" 22440013 miR-219-5p: Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-mir-302b "Carcinoma, Renal Cell" 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-mir-302c "Carcinoma, Renal Cell" 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-mir-367 "Carcinoma, Renal Cell" 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-mir-381 "Carcinoma, Renal Cell" 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-mir-451a "Carcinoma, Renal Cell" 22440013 Down-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_down hsa-mir-154 Graves Disease 22456620 "The expression of miR-154*, miR-376b, and miR-431* were suppressed in PBMC (peripheral blood mononuclear cells) from initial GD patients. In addition, their expression levels were recovered in GD patients in remission." circulation_biomarker_diagnosis_down hsa-mir-376b Graves Disease 22456620 "The expression of miR-154*, miR-376b, and miR-431* were suppressed in PBMC (peripheral blood mononuclear cells) from initial GD patients. In addition, their expression levels were recovered in GD patients in remission." circulation_biomarker_diagnosis_down hsa-mir-431 Graves Disease 22456620 "The expression of miR-154*, miR-376b, and miR-431* were suppressed in PBMC (peripheral blood mononuclear cells) from initial GD patients. In addition, their expression levels were recovered in GD patients in remission." circulation_biomarker_diagnosis_down hsa-mir-34a Colorectal Carcinoma 22648208 Circulating miR-34a levels are reduced in colorectal cancer. circulation_biomarker_diagnosis_down hsa-mir-361 "Carcinoma, Lung, Non-Small-Cell" 22675530 Low levels of cell-free circulating miR-361-3p and miR-625* could be blood-based markers for discriminating malignant from benign lung tumors. circulation_biomarker_diagnosis_down hsa-mir-625 "Carcinoma, Lung, Non-Small-Cell" 22675530 Low levels of cell-free circulating miR-361-3p and miR-625* could be blood-based markers for discriminating malignant from benign lung tumors. circulation_biomarker_diagnosis_down hsa-mir-181a-2 Breast Neoplasms 22692639 Decreased serum miR-181a is a potential new tool for breast cancer screening. circulation_biomarker_diagnosis_down hsa-let-7b Prostate Neoplasms 22719071 downregulated in prostate cancer stem/progenitor cell. circulation_biomarker_diagnosis_down hsa-mir-126 Myocardial Infarction 22719221 Increased miR-1 and decreased miR-126 in plasma from patients with AMI after the onset of symptoms compared with healthy subjects were found. circulation_biomarker_diagnosis_down hsa-mir-21 Lung Neoplasms 22782668 "In addition, miR-21 and miR-24 serum levels were lower in post-operative samples than those in pre-operative samples, suggesting they can potentially be used as biomarkers for disease recurrence after surgery operation." circulation_biomarker_diagnosis_down hsa-mir-24 Lung Neoplasms 22782668 "In addition, miR-21 and miR-24 serum levels were lower in post-operative samples than those in pre-operative samples, suggesting they can potentially be used as biomarkers for disease recurrence after surgery operation." circulation_biomarker_diagnosis_down hsa-mir-92a-1 Multiple Myeloma 22829237 Downregulated plasma miR-92a levels have clinical impact on multiple myeloma and related disorders. circulation_biomarker_diagnosis_down hsa-mir-155 Hepatitis C Virus Infection 22846613 Increased microRNA-155 expression in the serum and peripheral monocytes in chronic HCV infection. circulation_biomarker_diagnosis_down hsa-mir-218-1 Gastric Neoplasms 22860003 "The plasma levels of miR-223 (P<0.001) and miR-21 (P<0.001) were significantly higher in GC patients than in healthy controls, while miR-218 (P<0.001) was significantly lower. The ROC analyses yielded the AUC values of 0.9089 for miR-223, 0.7944 for miR-21 and 0.7432 for miR-218, and combined ROC analysis revealed the highest AUC value of 0.9531 in discriminating GC patients from healthy controls." circulation_biomarker_diagnosis_down hsa-mir-218-2 Gastric Neoplasms 22860003 "The plasma levels of miR-223 (P<0.001) and miR-21 (P<0.001) were significantly higher in GC patients than in healthy controls, while miR-218 (P<0.001) was significantly lower. The ROC analyses yielded the AUC values of 0.9089 for miR-223, 0.7944 for miR-21 and 0.7432 for miR-218, and combined ROC analysis revealed the highest AUC value of 0.9531 in discriminating GC patients from healthy controls." circulation_biomarker_diagnosis_down hsa-let-7c Lung Neoplasms 22862169 "Some miRNAs as hsa-miR-126, hsa-miR-145, hsa-let-7g, hsa-let-7d, hsa-let-7c, hsa-let-7e and hsa-miR-98, which were lowly expressed in SPC-A1 cells, were not expressed in the pulmospheres." circulation_biomarker_diagnosis_down hsa-let-7d Lung Neoplasms 22862169 "Some miRNAs as hsa-miR-126, hsa-miR-145, hsa-let-7g, hsa-let-7d, hsa-let-7c, hsa-let-7e and hsa-miR-98, which were lowly expressed in SPC-A1 cells, were not expressed in the pulmospheres." circulation_biomarker_diagnosis_down hsa-let-7e Lung Neoplasms 22862169 "Some miRNAs as hsa-miR-126, hsa-miR-145, hsa-let-7g, hsa-let-7d, hsa-let-7c, hsa-let-7e and hsa-miR-98, which were lowly expressed in SPC-A1 cells, were not expressed in the pulmospheres." circulation_biomarker_diagnosis_down hsa-let-7g Lung Neoplasms 22862169 "Some miRNAs as hsa-miR-126, hsa-miR-145, hsa-let-7g, hsa-let-7d, hsa-let-7c, hsa-let-7e and hsa-miR-98, which were lowly expressed in SPC-A1 cells, were not expressed in the pulmospheres." circulation_biomarker_diagnosis_down hsa-mir-126 Lung Neoplasms 22862169 "Some miRNAs as hsa-miR-126, hsa-miR-145, hsa-let-7g, hsa-let-7d, hsa-let-7c, hsa-let-7e and hsa-miR-98, which were lowly expressed in SPC-A1 cells, were not expressed in the pulmospheres." circulation_biomarker_diagnosis_down hsa-mir-145 Lung Neoplasms 22862169 "Some miRNAs as hsa-miR-126, hsa-miR-145, hsa-let-7g, hsa-let-7d, hsa-let-7c, hsa-let-7e and hsa-miR-98, which were lowly expressed in SPC-A1 cells, were not expressed in the pulmospheres." circulation_biomarker_diagnosis_down hsa-mir-98 Lung Neoplasms 22862169 "Some miRNAs as hsa-miR-126, hsa-miR-145, hsa-let-7g, hsa-let-7d, hsa-let-7c, hsa-let-7e and hsa-miR-98, which were lowly expressed in SPC-A1 cells, were not expressed in the pulmospheres." circulation_biomarker_diagnosis_down hsa-mir-409 Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_down hsa-mir-125b Prostate Neoplasms 22892455 An increase in serum miR-223 and a decrease in miR-125b and miR-146a were observed in group B. circulation_biomarker_diagnosis_down hsa-mir-146a Prostate Neoplasms 22892455 An increase in serum miR-223 and a decrease in miR-125b and miR-146a were observed in group B. circulation_biomarker_diagnosis_down hsa-mir-421 Gastric Neoplasms 22926798 Gastric juice microRNA-421 is a new biomarker for screening gastric cancer. circulation_biomarker_diagnosis_down hsa-mir-29a "Leukemia, Myeloid, Acute" 22981932 "Our data indicate for the first time that the down-regulation of miR-29a was associated with advanced clinical features and poor prognosis of pediatric AML patients, suggesting that miR-29a down-regulation may be used as an unfavorable prognostic marker in pediatric AML." circulation_biomarker_diagnosis_down hsa-mir-21 Breast Neoplasms 23052693 Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer circulation_biomarker_diagnosis_down hsa-mir-92a-1 Breast Neoplasms 23052693 Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer circulation_biomarker_diagnosis_down hsa-mir-92a-2 Breast Neoplasms 23052693 Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer circulation_biomarker_diagnosis_down hsa-mir-17 Systemic Lupus Erythematosus 23129428 Dual downregulation of microRNA 17-5p and E2F1 transcriptional factor in pediatric systemic lupus erythematosus patients circulation_biomarker_diagnosis_down hsa-mir-145 Systemic Lupus Erythematosus 23199328 Decreased microRNA(miR)-145 and increased miR-224 expression in T cells from patients with systemic lupus erythematosus involved in lupus immunopathogenesis circulation_biomarker_diagnosis_down hsa-mir-17 Endometriosis 23203215 "Plasma miR-17-5p, miR-20a and miR-22 are down-regulated in women with endometriosis" circulation_biomarker_diagnosis_down hsa-mir-20a Endometriosis 23203215 "Plasma miR-17-5p, miR-20a and miR-22 are down-regulated in women with endometriosis" circulation_biomarker_diagnosis_down hsa-mir-22 Endometriosis 23203215 "Plasma miR-17-5p, miR-20a and miR-22 are down-regulated in women with endometriosis" circulation_biomarker_diagnosis_down hsa-mir-146b "Leukemia, Lymphocytic, Chronic, B-Cell" 23286334 "we found that malignant B-cells from patients with CLL subsequently developing AIHA present nine down-regulated (i.e. miR-19a, miR-20a, miR-29c, miR-146b-5p, miR-186, miR-223, miR-324-3p, miR-484 and miR-660) miRNAs." circulation_biomarker_diagnosis_down hsa-mir-186 "Leukemia, Lymphocytic, Chronic, B-Cell" 23286334 "we found that malignant B-cells from patients with CLL subsequently developing AIHA present nine down-regulated (i.e. miR-19a, miR-20a, miR-29c, miR-146b-5p, miR-186, miR-223, miR-324-3p, miR-484 and miR-660) miRNAs." circulation_biomarker_diagnosis_down hsa-mir-19a "Leukemia, Lymphocytic, Chronic, B-Cell" 23286334 "we found that malignant B-cells from patients with CLL subsequently developing AIHA present nine down-regulated (i.e. miR-19a, miR-20a, miR-29c, miR-146b-5p, miR-186, miR-223, miR-324-3p, miR-484 and miR-660) miRNAs." circulation_biomarker_diagnosis_down hsa-mir-20a "Leukemia, Lymphocytic, Chronic, B-Cell" 23286334 "we found that malignant B-cells from patients with CLL subsequently developing AIHA present nine down-regulated (i.e. miR-19a, miR-20a, miR-29c, miR-146b-5p, miR-186, miR-223, miR-324-3p, miR-484 and miR-660) miRNAs." circulation_biomarker_diagnosis_down hsa-mir-223 "Leukemia, Lymphocytic, Chronic, B-Cell" 23286334 "we found that malignant B-cells from patients with CLL subsequently developing AIHA present nine down-regulated (i.e. miR-19a, miR-20a, miR-29c, miR-146b-5p, miR-186, miR-223, miR-324-3p, miR-484 and miR-660) miRNAs." circulation_biomarker_diagnosis_down hsa-mir-29c "Leukemia, Lymphocytic, Chronic, B-Cell" 23286334 "we found that malignant B-cells from patients with CLL subsequently developing AIHA present nine down-regulated (i.e. miR-19a, miR-20a, miR-29c, miR-146b-5p, miR-186, miR-223, miR-324-3p, miR-484 and miR-660) miRNAs." circulation_biomarker_diagnosis_down hsa-mir-324 "Leukemia, Lymphocytic, Chronic, B-Cell" 23286334 "we found that malignant B-cells from patients with CLL subsequently developing AIHA present nine down-regulated (i.e. miR-19a, miR-20a, miR-29c, miR-146b-5p, miR-186, miR-223, miR-324-3p, miR-484 and miR-660) miRNAs." circulation_biomarker_diagnosis_down hsa-mir-484 "Leukemia, Lymphocytic, Chronic, B-Cell" 23286334 "we found that malignant B-cells from patients with CLL subsequently developing AIHA present nine down-regulated (i.e. miR-19a, miR-20a, miR-29c, miR-146b-5p, miR-186, miR-223, miR-324-3p, miR-484 and miR-660) miRNAs." circulation_biomarker_diagnosis_down hsa-mir-660 "Leukemia, Lymphocytic, Chronic, B-Cell" 23286334 "we found that malignant B-cells from patients with CLL subsequently developing AIHA present nine down-regulated (i.e. miR-19a, miR-20a, miR-29c, miR-146b-5p, miR-186, miR-223, miR-324-3p, miR-484 and miR-660) miRNAs." circulation_biomarker_diagnosis_down hsa-mir-198 Lung Neoplasms 23354517 Circulating;Downregulation of cell-free miR-198 as a diagnostic biomarker for lung adenocarcinoma-associated malignant pleural effusion circulation_biomarker_diagnosis_down hsa-mir-150 Sepsis 23372743 Circulating;Circulating MicroRNA-150 Serum Levels Predict Survival in Patients with Critical Illness and Sepsis circulation_biomarker_diagnosis_down hsa-mir-30a Breast Neoplasms 23389917 plasma; plasma miRNA-30a decreased in patients with BC and has great potential to use as novel biomarkers for BC diagnosis circulation_biomarker_diagnosis_down hsa-mir-106a Systemic Lupus Erythematosus 23401079 "Seven miRNAs were statistically significantly differentially expressed in plasma from patients with SLE. The expression of miRNA-142-3p (miR-142-3p) and miR-181a was increased, and the expression of miR-106a, miR-17, miR-20a, miR-203,and miR-92a was decreased" circulation_biomarker_diagnosis_down hsa-mir-17 Systemic Lupus Erythematosus 23401079 "Seven miRNAs were statistically significantly differentially expressed in plasma from patients with SLE. The expression of miRNA-142-3p (miR-142-3p) and miR-181a was increased, and the expression of miR-106a, miR-17, miR-20a, miR-203,and miR-92a was decreased" circulation_biomarker_diagnosis_down hsa-mir-203 Systemic Lupus Erythematosus 23401079 "Seven miRNAs were statistically significantly differentially expressed in plasma from patients with SLE. The expression of miRNA-142-3p (miR-142-3p) and miR-181a was increased, and the expression of miR-106a, miR-17, miR-20a, miR-203,and miR-92a was decreased" circulation_biomarker_diagnosis_down hsa-mir-20a Systemic Lupus Erythematosus 23401079 "Seven miRNAs were statistically significantly differentially expressed in plasma from patients with SLE. The expression of miRNA-142-3p (miR-142-3p) and miR-181a was increased, and the expression of miR-106a, miR-17, miR-20a, miR-203,and miR-92a was decreased" circulation_biomarker_diagnosis_down hsa-mir-92a Systemic Lupus Erythematosus 23401079 "Seven miRNAs were statistically significantly differentially expressed in plasma from patients with SLE. The expression of miRNA-142-3p (miR-142-3p) and miR-181a was increased, and the expression of miR-106a, miR-17, miR-20a, miR-203,and miR-92a was decreased" circulation_biomarker_diagnosis_down hsa-mir-133 Heart Failure 23711953 "In surgical CAD patients, a decreased miR-133 expression is associated with variables characteristic of heart failure." circulation_biomarker_diagnosis_down hsa-mir-197 Primary Biliary Cirrhosis 23776611 Our results indicate that sera from patients with PBC have a unique mirNA expression profile and that the down-regulated expression of mir-505-3p and mir-197-3p can serve as clinical biomarkers of PBC. circulation_biomarker_diagnosis_down hsa-mir-505 Primary Biliary Cirrhosis 23776611 Our results indicate that sera from patients with PBC have a unique mirNA expression profile and that the down-regulated expression of mir-505-3p and mir-197-3p can serve as clinical biomarkers of PBC. circulation_biomarker_diagnosis_down hsa-let-7f Alzheimer Disease 23895045 A blood based 12-miRNA signature of Alzheimer disease patients. circulation_biomarker_diagnosis_down hsa-mir-103a Alzheimer Disease 23895045 A blood based 12-miRNA signature of Alzheimer disease patients. circulation_biomarker_diagnosis_down hsa-mir-107 Alzheimer Disease 23895045 A blood based 12-miRNA signature of Alzheimer disease patients. circulation_biomarker_diagnosis_down hsa-mir-1285 Alzheimer Disease 23895045 A blood based 12-miRNA signature of Alzheimer disease patients. circulation_biomarker_diagnosis_down hsa-mir-26a Alzheimer Disease 23895045 A blood based 12-miRNA signature of Alzheimer disease patients. circulation_biomarker_diagnosis_down hsa-mir-26b Alzheimer Disease 23895045 A blood based 12-miRNA signature of Alzheimer disease patients. circulation_biomarker_diagnosis_down hsa-mir-532 Alzheimer Disease 23895045 A blood based 12-miRNA signature of Alzheimer disease patients. circulation_biomarker_diagnosis_down hsa-mir-145 Myasthenia Gravis 24043548 Identification of novel MicroRNA signatures linked to experimental autoimmune myasthenia gravis pathogenesis: down-regulated miR-145 promotes pathogenetic Th17 cell response. circulation_biomarker_diagnosis_down hsa-mir-21 Leukemia 24141112 "Moreover, the down-regulated expression of microRNA-21 in DF-1 chicken fibroblast cells infected with subgroup J avian leukemia virus (ALVs) was confirmed by the developed method, indicating that microRNA-21 might be a new biomarker for avian leukemia." circulation_biomarker_diagnosis_down hsa-mir-15b Multiple Sclerosis 24277735 Decreased circulating miRNA levels in patients with primary progressive multiple sclerosis. circulation_biomarker_diagnosis_down hsa-mir-223 Multiple Sclerosis 24277735 Decreased circulating miRNA levels in patients with primary progressive multiple sclerosis. circulation_biomarker_diagnosis_down hsa-mir-23a Multiple Sclerosis 24277735 Decreased circulating miRNA levels in patients with primary progressive multiple sclerosis. circulation_biomarker_diagnosis_down hsa-mir-1 Polycystic Kidney Disease 24489795 "We found that in ADPKD urine specimens, miRNA previously implicated as kidney tumor suppressors (miR-1 and miR-133), as well as miRNA of presumed inflammatory and fibroblast cell origin (miR-223/miR-199), are dysregulated when compared to other CKD patients. Concordant with findings in the primary tubule epithelial cell model, this suggests roles for dysregulated miRNA in ADPKD pathogenesis and potential use as biomarkers. We intend to assess prognostic potential of miRNA in a followup analysis." circulation_biomarker_diagnosis_down hsa-mir-29a Parkinson Disease 24648008 "We found four statistically significant miRNAs that were downregulated in either LRRK2 or IPD (miR-29a, miR-29c, miR-19a, and miR-19b)." circulation_biomarker_diagnosis_down hsa-mir-96 "Leukemia, Myeloid, Acute" 24678958 "Our data demonstrated that the expression of miR-96 was downregulated in newly diagnosed AML patients and associated with leukemic burden, as well as RFS and OS. This suggests that miR-96 detection might become a potential biomarker of prognosis and monitoring in AML." circulation_biomarker_diagnosis_down hsa-mir-199b "Leukemia, Myeloid, Chronic" 24680705 Down-regulation of miR-199b associated with imatinib drug resistance in 9q34.1 deleted BCR/ABL positive CML patients. circulation_biomarker_diagnosis_down hsa-let-7e Retinoblastoma 24748987 "Plasma miRNA (miR)-320, miR-let-7e and miR-21 levels were downregulated in the patient samples" circulation_biomarker_diagnosis_down hsa-mir-146 "Diabetes Mellitus, Type 1" 24796653 Decreased miR-146 expression in peripheral blood mononuclear cells is correlated with ongoing islet autoimmunity in type 1 diabetes patients 1miR-146. circulation_biomarker_diagnosis_down hsa-mir-125b Melanoma 24878024 "Exosomes can provide a suitable material to measure circulating miRNA in melanoma, and miR-16 can be used as an endogenous normalizer. Lower levels of miR-125b in exosomes obtained from serum are associated with advanced melanoma disease, probably reflecting the tumoral cell dysregulation." circulation_biomarker_diagnosis_down hsa-mir-16 Melanoma 24878024 "Exosomes can provide a suitable material to measure circulating miRNA in melanoma, and miR-16 can be used as an endogenous normalizer. Lower levels of miR-125b in exosomes obtained from serum are associated with advanced melanoma disease, probably reflecting the tumoral cell dysregulation." circulation_biomarker_diagnosis_down hsa-mir-107 Diabetes Mellitus 24908639 "Hyperglycemia may downregulate the expressions of miR-223 and miR-146a, leading to subsequent platelet activation in patients with diabetes mellitus. Low platelet and plasma miR-223 and miR-146a expression is a risk factor for ischemic stroke in Chinese diabetes mellitus patients." circulation_biomarker_diagnosis_down hsa-mir-146a Diabetes Mellitus 24908639 "Hyperglycemia may downregulate the expressions of miR-223 and miR-146a, leading to subsequent platelet activation in patients with diabetes mellitus. Low platelet and plasma miR-223 and miR-146a expression is a risk factor for ischemic stroke in Chinese diabetes mellitus patients." circulation_biomarker_diagnosis_down hsa-mir-223 Diabetes Mellitus 24908639 "Hyperglycemia may downregulate the expressions of miR-223 and miR-146a, leading to subsequent platelet activation in patients with diabetes mellitus. Low platelet and plasma miR-223 and miR-146a expression is a risk factor for ischemic stroke in Chinese diabetes mellitus patients." circulation_biomarker_diagnosis_down hsa-mir-495 Diabetes Mellitus 24908639 "Hyperglycemia may downregulate the expressions of miR-223 and miR-146a, leading to subsequent platelet activation in patients with diabetes mellitus. Low platelet and plasma miR-223 and miR-146a expression is a risk factor for ischemic stroke in Chinese diabetes mellitus patients." circulation_biomarker_diagnosis_down hsa-let-7b Crohn Disease 24910152 Both inflamed and non-inflamed terminal ileal mucosa in adult patients with active CD have their distinct miRNA expression patterns compared with healthy controls. Dysregulated miRNAs may be responsible for pathogenesis of CD. circulation_biomarker_diagnosis_down hsa-mir-9-1 Methylmalonic Acidemia 24927441 "Plasma miR-9-1 is significantly down-regulated in MMA patients, but it is significantly up-regulated after vitamin B12 treatment, suggesting that miR-9-1 may act as a biomarker in monitoring the progression of MMA." circulation_biomarker_diagnosis_down hsa-mir-155 Sjogren Syndrome 24931100 "Our results demonstrated miR-146a overexpression and miR-155 underexpression in the peripheral mononuclear blood cells of the patients with pSS. Furthermore, the expression levels of these miRNAs correlated with the patients' clinical features. Our data suggest that miR-146a and miR-155 might play important roles in the pathogenesis of pSS and that their expression levels may be useful for diagnosing pSS and for predicting disease activity and therapeutic responses." circulation_biomarker_diagnosis_down hsa-mir-1 Bladder Neoplasms 25015192 Hsa-miR-1 downregulates long non-coding RNA urothelial cancer associated 1 in bladder cancer. circulation_biomarker_diagnosis_down hsa-mir-16 Heart Failure 25033200 "We provide evidence that miR-16 decreases in the circulation of end-stage HF patients and increases with a LVAD. Modeling studies suggest that miR-16 binds to and decreases expression of VPS4a. Overexpression of VPS4a decreases cell number. Together, these experiments suggest that miR-16 and VPS4a expression are altered in end-stage HF and in response to unloading with a LVAD. This signaling pathway may lead to reduced circulating cell number in HF." circulation_biomarker_diagnosis_down hsa-mir-195 Breast Neoplasms 25103018 Serum microRNA-195 is down-regulated in breast cancer: a potential marker for the diagnosis of breast cancer. circulation_biomarker_diagnosis_down hsa-mir-181b Autism Spectrum Disorder 25126405 "MiR-151a-3p, miR-181b-5p, miR-320a, miR-328, miR-433, miR-489, miR-572, and miR-663a were downregulated, while miR-101-3p, miR-106b-5p, miR-130a-3p, miR-195-5p, and miR-19b-3p were upregulated." circulation_biomarker_diagnosis_down hsa-mir-21 Rheumatoid Arthritis 25164131 Decreased expression of microRNA-21 correlates with the imbalance of Th17 and Treg cells in patients with rheumatoid arthritis. circulation_biomarker_diagnosis_down hsa-mir-146b "Fatty Liver, Non-Alcoholic" 25232454 "Serum levels of miR-181d, miR-99a, miR-197 and miR-146b were significantly lower in biopsy-proven NAFLD patients than in the healthy controls." circulation_biomarker_diagnosis_down hsa-mir-29a "Fatty Liver, Non-Alcoholic" 25232454 "Serum levels of miR-181d, miR-99a, miR-197 and miR-146b were significantly lower in biopsy-proven NAFLD patients than in the healthy controls." circulation_biomarker_diagnosis_down hsa-mir-124 Stroke 25257664 serum miR-124 was significantly decreased within 24 hours after stroke onset and serum miR-9 was decreased in patients with larger stroke. circulation_biomarker_diagnosis_down hsa-mir-9 Stroke 25257664 serum miR-124 was significantly decreased within 24 hours after stroke onset and serum miR-9 was decreased in patients with larger stroke. circulation_biomarker_diagnosis_down hsa-mir-150 Sepsis 25394245 "The expression of two miRNAs, that is, let-7a (P < 0.001) and miR-150 (P < 0.001), were confirmed to be significantly downregulated in GNB urosepsis patients compared with healthy controls." circulation_biomarker_diagnosis_down hsa-mir-320a Multiple Sclerosis 25468268 expression of miR-320a is decreased in B cells of MS patients and may contribute to increased blood-brain barrier permeability and neurological disability. circulation_biomarker_diagnosis_down hsa-mir-210 Acute Cerebral Infarction 25476086 "The serum level of miR-210 in ACI was significantly lower than that in normal healthy persons, and it may be an important new serological marker in screening and diagnosis of ACI." circulation_biomarker_diagnosis_down hsa-mir-146a "Diabetes Mellitus, Type 2" 25500583 "decreased serum anti-inflammatory miR-146a, increased pro-inflammatory IL-8 and increased HGF (a vascular/insular repair factor) as discriminating markers of failure of glucose control occurring on the background of obesity and dyslipidemia." circulation_biomarker_diagnosis_down hsa-mir-155 "Diabetes Mellitus, Type 2" 25500583 "decreased serum anti-inflammatory miR-146a, increased pro-inflammatory IL-8 and increased HGF (a vascular/insular repair factor) as discriminating markers of failure of glucose control occurring on the background of obesity and dyslipidemia." circulation_biomarker_diagnosis_down hsa-mir-22 Premature Ovarian Failure 25585503 Mir-22-3p showed a lower expression level in POF and was modestly effective in distinguishing POF from control subjects. The decreased expression of miR-22-3p in plasma of POF may reflect the diminished ovarian reserve and be a consequence of the pathologic process of POF. circulation_biomarker_diagnosis_down hsa-mir-1 Arrhythmia 25625292 patients with SVT had lower miR-1 expression levels while those with VT had higher miR-133 expression levels. circulation_biomarker_diagnosis_down hsa-mir-223 "Leukemia, Myeloid, Acute" 25793640 MIR233 is genetically or epigenetically silenced in a subset of acute myeloid leukemia (AML). circulation_biomarker_diagnosis_down hsa-mir-218 "Carcinoma, Esophageal" 25812647 "The serum expression of miR-218 is downregulated in esophageal cancer patients and is correlated with tumor differentiation, stage, and lymph node metastasis. Serum miR-218 may be a potential biomarker for early detection and clinical evaluation in patient with esophageal cancer." circulation_biomarker_diagnosis_down hsa-mir-181b Atherosclerosis 25896908 Hyperlipidemia reduced the expression of miR-181b and increased NT and N/M ratio. circulation_biomarker_diagnosis_down hsa-mir-16 Plasmodium vivax Infection 25913668 Downregulation of plasma miR-451 and miR-16 in Plasmodium vivax infection. circulation_biomarker_diagnosis_down hsa-mir-451 Plasmodium vivax Infection 25913668 Downregulation of plasma miR-451 and miR-16 in Plasmodium vivax infection. circulation_biomarker_diagnosis_down hsa-mir-148a "Leukemia, Myeloid, Acute" 25924238 whilst anti-oncogenic microRNAsincluding miR-148a and miR-193a were down-regulated in MAPKBP1high patients with CN-AML circulation_biomarker_diagnosis_down hsa-mir-214 Acute Myocardial Infarction 25931214 "The circulating level of miR-214 was significantly decreased in the AMI group, which might be correlated with the extent of the coronary lesion.Circulating miR-214 may be a promising biomarker for the diagnosis and prognosis of severe AMI." circulation_biomarker_diagnosis_down hsa-mir-145 Coronary Artery Disease 25938589 "Lower plasma levels of miRNA-145 were significantly associated with the presence as well as severity of CAD. As a potential biomarker for CAD, plasma miRNA-145 may be useful in predicting CAD and its severity in patients presenting with chest pain." circulation_biomarker_diagnosis_down hsa-mir-22 Rheumatoid Arthritis 25939484 "MiRNAs with a P-value <0.05 using three different normalizations were included in a multivariate model.After backwards elimination, the combination of low expression of miR-22 and high expression of miR-886.3p was associated with EULAR good response. Future studies to assess the utility of these miRNAs as predictive biomarkers are needed." circulation_biomarker_diagnosis_down hsa-mir-181c Myasthenia Gravis 25962782 Decreased microRNA miR-181c expression in peripheral blood mononuclear cells correlates with elevated serum levels of IL-7 and IL-17 in patients with myasthenia gravis. circulation_biomarker_diagnosis_down hsa-mir-130a Spinal Cord Injuries 25973054 Increased HDAC3 and decreased miRNA-130a expression in PBMCs through recruitment HDAC3 in patients with spinal cord injuries. circulation_biomarker_diagnosis_down hsa-mir-126 Atherosclerosis 25975504 miR-126 and miR-223 platelets were reduced in the rabbit atherosclerotic plaque model group circulation_biomarker_diagnosis_down hsa-mir-33b Multiple Myeloma 25975752 Downregulated miR-33b is a novel predictor associated with disease progression and poor prognosis in multiple myeloma. circulation_biomarker_diagnosis_down hsa-mir-374a Hypoxic-Ischemic Encephalopathy 26001314 We have shown a significant step-wise downregulation of hsa-miR-374a expression in cord blood of infants with perinatal asphyxia and subsequent HIE. circulation_biomarker_diagnosis_down hsa-mir-146a "Stroke, Ischemic" 26044809 miR-146a and miR-185 were present with quite low abundance in ISA compared with healthy individuals circulation_biomarker_diagnosis_down hsa-mir-143 Alzheimer Disease 26078483 "The results showed that four miRNAs (miR-31, miR-93, miR-143, and miR-146a) were markedly decreased in AD patients'serum compared with controls." circulation_biomarker_diagnosis_down hsa-mir-146a Alzheimer Disease 26078483 "The results showed that four miRNAs (miR-31, miR-93, miR-143, and miR-146a) were markedly decreased in AD patients'serum compared with controls." circulation_biomarker_diagnosis_down hsa-mir-31 Alzheimer Disease 26078483 "The results showed that four miRNAs (miR-31, miR-93, miR-143, and miR-146a) were markedly decreased in AD patients'serum compared with controls." circulation_biomarker_diagnosis_down hsa-mir-93 Alzheimer Disease 26078483 "The results showed that four miRNAs (miR-31, miR-93, miR-143, and miR-146a) were markedly decreased in AD patients'serum compared with controls." circulation_biomarker_diagnosis_down hsa-mir-378 Dengue Virus Infection 26166761 "This study found that miR-27a*, miR-30e, and miR-378 were down-regulated in DENV-infected patients" circulation_biomarker_diagnosis_down hsa-mir-155 Diabetes Mellitus 26188366 Downregulated microRNA-155 expression in peripheral blood mononuclear cells of type 2 diabetic patients is not correlated with increased inflammatory cytokine production. circulation_biomarker_diagnosis_down hsa-mir-130b Heart Failure 26211628 MiR-130b levels were reduced in obese HF patients compared with HF lean (P=0.036) and controls (P=0.025). circulation_biomarker_diagnosis_down hsa-mir-143 Obesity 26223376 "Circulating miR-335 (Pâ€?â€?.001), miR-143 (Pâ€?â€?.001) and miR-758 (Pâ€?â€?.006) in obese children were significantly lower than those of controls." circulation_biomarker_diagnosis_down hsa-mir-335 Obesity 26223376 "Circulating miR-335 (Pâ€?â€?.001), miR-143 (Pâ€?â€?.001) and miR-758 (Pâ€?â€?.006) in obese children were significantly lower than those of controls." circulation_biomarker_diagnosis_down hsa-mir-205 Glioma 26230475 Downregulation of serum microRNA-205 as a potential diagnostic and prognostic biomarker for human glioma. circulation_biomarker_diagnosis_down hsa-mir-203 Gastric Neoplasms 26233325 serum miR-203 levels were significantly lower in stage IV than stage I-III GC patients. circulation_biomarker_diagnosis_down hsa-mir-126 Diabetes Mellitus 26299579 Diabetes mellitus circulation_biomarker_diagnosis_down hsa-mir-181b Atherosclerosis 26420120 The serum miR-181b level was significantly reduced in patients with atherosclerosis. miR-181b may function as an atherosclerosis suppressor by interupting the NF-¦ÊB pathway in endothelial cells and inhibiting the proliferation and migration of vascular smooth muscle cells. circulation_biomarker_diagnosis_down hsa-mir-15a Diabetes Mellitus 26460159 "These results demonstrated that peripheral blood miR-15a expression levels were significantly lower in patients with T2D and IFG/IGT individuals, compared with healthy individuals. Thus, miR-15a in peripheral whole blood may serve as a potential biomarker for T2D and pre-diabetes." circulation_biomarker_diagnosis_down hsa-mir-106a Cholangiocarcinoma 26534789 "Together, reduced expression of serum miR-106a is a powerful prognostic indicator for CCA patients. The dismal outcome of these CCA patients might correlate with a higher risk of lymph node metastasis." circulation_biomarker_diagnosis_down hsa-mir-27a Acute Heart Failure 26569364 "The increase in creatinine during the first 3 days of hospitalization was significantly associated with lower levels of miR-199a-3p, miR-27a-3p, miR-652-3p, miR-423-5p, and miR-let-7i-5p" circulation_biomarker_diagnosis_down hsa-mir-126 Acute Heart Failure 26580972 Levels of miR-126 and miR-423-5p were lower in AHF and in non-AHF patients compared to stable CHF patients (both p<0.001). circulation_biomarker_diagnosis_down hsa-mir-122 Stroke 26661204 our recent studies have demonstrated that miR-122 decreased in whole blood of patients and in whole blood of rats following ischemic stroke circulation_biomarker_diagnosis_down hsa-mir-150 Spondylarthritis 26689798 miR-150 was downregulated in all of the samples circulation_biomarker_diagnosis_down hsa-mir-181a "Leukemia, Myeloid, Chronic" 26722250 The expression levels of miR-181a were significantly reduced in the patient with CML and in the CML K562 cell line. circulation_biomarker_diagnosis_down hsa-mir-106b Human Immunodeficiency Virus Infection 26755399 we found that the miRNAs miR-106b and miR-20a that target p21 were specifically downregulated in HIV-1 infected CD4+ T cells. circulation_biomarker_diagnosis_down hsa-mir-20a Human Immunodeficiency Virus Infection 26755399 we found that the miRNAs miR-106b and miR-20a that target p21 were specifically downregulated in HIV-1 infected CD4+ T cells. circulation_biomarker_diagnosis_down hsa-mir-146a "Squamous Cell Carcinoma, Esophageal" 26794279 MicroRNA-146a is significantly reduced in cancerous tissue and serum samples of ESCC patients. It is an ideal biomarker for the prognosis and diagnosis of ESCC. circulation_biomarker_diagnosis_down hsa-mir-221 Prostate Neoplasms 26831660 downregulation of hsa-miR-221* (now hsa-miR-221-5p) and hsa-miR-708* (now hsa-miR-708-3p) in PCa compared to BPH. circulation_biomarker_diagnosis_down hsa-mir-708 Prostate Neoplasms 26831660 downregulation of hsa-miR-221* (now hsa-miR-221-5p) and hsa-miR-708* (now hsa-miR-708-3p) in PCa compared to BPH. circulation_biomarker_diagnosis_down hsa-mir-199b "Leukemia, Myeloid, Acute" 26848406 Low miR-199b in AML patients correlates with worse overall survival and has prognostic significance for FAB-M5 subtype. circulation_biomarker_diagnosis_down hsa-mir-199b Polycystic Ovarian Syndrome 26860517 whereas that of miR-199b-5p was down-regulated. circulation_biomarker_diagnosis_down hsa-mir-34b "Leukemia, Myeloid, Acute, Pediatric" 26861642 miRâ€?4b levels in leukemia cell lines and primary leukemic cells were significantly lower than those in normal cells. circulation_biomarker_diagnosis_down hsa-mir-194 Cholangiocarcinoma 26864161 miR-483-5p and miR-194 showed deregulated expression in CC compared with controls. circulation_biomarker_diagnosis_down hsa-mir-483 Cholangiocarcinoma 26864161 whereas miR-483-5p and miR-194 showed deregulated expression in CC compared with controls circulation_biomarker_diagnosis_down hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 26908869 Downregulation of miR-15a and miR-16-1 at 13q14 in Chronic Lymphocytic Leukemia. circulation_biomarker_diagnosis_down hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 26908869 Downregulation of miR-15a and miR-16-1 at 13q14 in Chronic Lymphocytic Leukemia. circulation_biomarker_diagnosis_down hsa-mir-126 Diabetes Mellitus 27005938 "Among those, miR-126 and miR-26a were significantly reduced in diabetic patients compared to non-diabetic patients." circulation_biomarker_diagnosis_down hsa-mir-20a Endometriosis 27049094 "For recurred cases, miR-199 showed a remarkably high expression and miR-17-5p and miR-20a expressed significantly low." circulation_biomarker_diagnosis_down hsa-mir-155 Chronic Hepatitis B 27110261 "In the HBV-infected patients, the miR-155 levels were significantly lower than in the healthy controls" circulation_biomarker_diagnosis_down hsa-mir-106a Aortic Stenosis 27129184 "Levels of miR-30c were higher in the AS group than in the controls (P<0.01), whereas levels of miR-106a, miR-148a, miR-204, miR-211, miR-31 and miR-424 were lower in the AS group than in the controls (P<0.01)." circulation_biomarker_diagnosis_down hsa-mir-148a Aortic Stenosis 27129184 "Levels of miR-30c were higher in the AS group than in the controls (P<0.01), whereas levels of miR-106a, miR-148a, miR-204, miR-211, miR-31 and miR-424 were lower in the AS group than in the controls (P<0.01)." circulation_biomarker_diagnosis_down hsa-mir-204 Aortic Stenosis 27129184 "Levels of miR-30c were higher in the AS group than in the controls (P<0.01), whereas levels of miR-106a, miR-148a, miR-204, miR-211, miR-31 and miR-424 were lower in the AS group than in the controls (P<0.01)." circulation_biomarker_diagnosis_down hsa-mir-211 Aortic Stenosis 27129184 "Levels of miR-30c were higher in the AS group than in the controls (P<0.01), whereas levels of miR-106a, miR-148a, miR-204, miR-211, miR-31 and miR-424 were lower in the AS group than in the controls (P<0.01)." circulation_biomarker_diagnosis_down hsa-mir-30a Aortic Stenosis 27129184 "Levels of miR-30c were higher in the AS group than in the controls (P<0.01), whereas levels of miR-106a, miR-148a, miR-204, miR-211, miR-31 and miR-424 were lower in the AS group than in the controls (P<0.01)." circulation_biomarker_diagnosis_down hsa-mir-31 Aortic Stenosis 27129184 "Levels of miR-30c were higher in the AS group than in the controls (P<0.01), whereas levels of miR-106a, miR-148a, miR-204, miR-211, miR-31 and miR-424 were lower in the AS group than in the controls (P<0.01)." circulation_biomarker_diagnosis_down hsa-mir-424 Aortic Stenosis 27129184 "Levels of miR-30c were higher in the AS group than in the controls (P<0.01), whereas levels of miR-106a, miR-148a, miR-204, miR-211, miR-31 and miR-424 were lower in the AS group than in the controls (P<0.01)." circulation_biomarker_diagnosis_down hsa-mir-1297 "Squamous Cell Carcinoma, Esophageal" 27152453 It was statistically decreased in ESCC patients compared with healthy controls. circulation_biomarker_diagnosis_down hsa-mir-125b "Carcinoma, Hepatocellular, HBV-Related" 27152955 The levels of plasma miR-125b were remarkably decreased in HBV-HCC patients compared to healthy controls circulation_biomarker_diagnosis_down hsa-mir-181a Human Immunodeficiency Virus Infection 27171002 "hsa-miR-155 and hsa-miR-181a were downregulated in VP whereas in the other groups, either an upregulation or no differences were observed after stimulation, respectively." circulation_biomarker_diagnosis_down hsa-mir-200c Breast Neoplasms 27197674 "miR-21 (P < 0.001) and miR-146a (P = 0.001) were overexpressed, whereas miR-200c (P = 0.004) and miR-210 (P = 0.002) were underexpressed." circulation_biomarker_diagnosis_down hsa-mir-210 Breast Neoplasms 27197674 "miR-21 (P < 0.001) and miR-146a (P = 0.001) were overexpressed, whereas miR-200c (P = 0.004) and miR-210 (P = 0.002) were underexpressed." circulation_biomarker_diagnosis_down hsa-mir-182 Atherosclerosis 27199451 Atherosclerotic lesions from patients with high asymmetrical dimethylarginine plasma levels exhibited decreased miR-182-3p expression levels and elevated MYADM expression levels. circulation_biomarker_diagnosis_down hsa-mir-181a Allergic Rhinitis 27199509 The OPN protein and miR-181a levels may serve as predictors of disease severity in childhood AR and appear to be promising targets for modulating AR. circulation_biomarker_diagnosis_down hsa-mir-19a Lung Fibrosis 27312312 miR-19a in peripheral blood leukocyte could be used as an effective biomarker for silicosis circulation_biomarker_diagnosis_down hsa-mir-126 Coronary Artery Disease 27321479 MiR-126 strongly associated with T2D and CAD circulation_biomarker_diagnosis_down hsa-mir-126 "Diabetes Mellitus, Type 2" 27321479 "expression levels of circulating miR-126, determined by quantitative real time PCR, were decrease in peripheral blood of T2D patients and T2D with CAD compared with healthy controls." circulation_biomarker_diagnosis_down hsa-mir-30 Atherosclerosis 27379414 circulating miR-30 might be used as a biomarker for atherosclerosis circulation_biomarker_diagnosis_down hsa-mir-375 Diabetes Mellitus 27383196 lower circulating levels of miR-192 and miR-375 compared to CD period circulation_biomarker_diagnosis_down hsa-mir-4505 Anxiety Disorders 27423364 "Results showed that the level of miR-4505 and miR-663 was negatively correlated with the total HAMA scores in GAD patients (r=0.2228, r=0.264 P<0.05)." circulation_biomarker_diagnosis_down hsa-mir-663 Anxiety Disorders 27423364 "esults showed that the level of miR-4505 and miR-663 was negatively correlated with the total HAMA scores in GAD patients (r=0.2228, r=0.264 P<0.05)." circulation_biomarker_diagnosis_down hsa-mir-320b Carotid Artery Diseases 27460454 Low serum miR-320b expression as a novel indicator of carotid atherosclerosis. circulation_biomarker_diagnosis_down hsa-mir-335 Spinal Muscular Atrophy 27483257 The expression of miR-335-5p; already identified to control self-renewal or differentiation of mouse embryonic stem cells (mESCs); resulted to be reduced during the early steps of differentiation of SMA hiPSCs compared to wild type cells. circulation_biomarker_diagnosis_down hsa-mir-31 Systemic Lupus Erythematosus 27510529 "The results revealed that miR-31 was lower expressed, while miR-21 was high expressed in SLE patients compared to their first-degree relatives and controls." circulation_biomarker_diagnosis_down hsa-mir-200b Kideny Transplant Rejection 27521993 our findings indicated that the aberrant urinary miR-21 and miR-200b expression levels were accompanied with renal allograft dysfunction and IFTA. circulation_biomarker_diagnosis_down hsa-mir-29a "Leukemia, Lymphoblastic" 27535859 "The expression of hsa-miR-29a , hsa-miR-126 and has-miR-181 family were significantly different in B-ALL." circulation_biomarker_diagnosis_down hsa-mir-663 Leukemia 27535859 "The expression of hsa-miR-29a , hsa-miR-126 and has-miR-181 family were significantly different in B-ALL." circulation_biomarker_diagnosis_down hsa-mir-150 Cholangiocarcinoma 27658773 Profiling of downregulated blood-circulating miR-150-5p as a novel tumor marker for cholangiocarcinoma. circulation_biomarker_diagnosis_down hsa-mir-155 "Fatty Liver, Non-Alcoholic" 27832630 Decreased MiR-155 Level in the Peripheral Blood of Non-Alcoholic Fatty Liver Disease Patients may Serve as a Biomarker and may Influence LXR Activity. circulation_biomarker_diagnosis_down hsa-mir-335 Acute Ischemic Stroke 27856935 Decreased plasma miR-335 expression in patients with acute ischemic stroke and its association with calmodulin expression. circulation_biomarker_diagnosis_down hsa-mir-126 Cardiovascular Diseases [unspecific] 28065883 Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy. circulation_biomarker_diagnosis_down hsa-mir-132 Cardiovascular Diseases [unspecific] 28065883 Down-regulation of proangiogenic microRNA-126 and microRNA-132 are early modulators of diabetic cardiac microangiopathy. circulation_biomarker_diagnosis_down hsa-mir-27a Heart Failure 28293796 Low circulating microRNA levels in heart failure patients are associated with atherosclerotic disease and cardiovascular-related rehospitalizations. circulation_biomarker_diagnosis_down hsa-mir-204 Aortic Valve Disease 28377507 miR-486 inhibits Smurf2 expression to augment the miR-204 down-regulation circulation_biomarker_diagnosis_down hsa-mir-150 "Leukemia, Lymphocytic, Chronic, B-Cell" 28407516 Quantitative miR analysis in chronic lymphocytic leukaemia/small lymphocytic lymphoma - proliferation centres are characterized by high miR-92a and miR-155 and low miR-150 expression. circulation_biomarker_diagnosis_down hsa-mir-155 Myocardial Infarction 28618412 Failed Downregulation of Circulating MicroRNA-155 in the Early Phase after ST Elevation Myocardial Infarction Is Associated with Adverse Left Ventricular Remodeling. circulation_biomarker_diagnosis_down hsa-mir-133a Vascular Hypertrophy 28772031 Local microRNA-133a downregulation is associated with hypertrophy in the dyssynchronous heart. circulation_biomarker_diagnosis_down hsa-let-7f "Leukemia, Lymphoblastic, Acute, Childhood" 28910942 "The expression levels of let-7f-5p, miR-5100 and miR-25-3p in the cALL patients were significantly lower than those of the controls" circulation_biomarker_diagnosis_down hsa-mir-25 "Leukemia, Lymphoblastic, Acute, Childhood" 28910942 "The expression levels of let-7f-5p, miR-5100 and miR-25-3p in the cALL patients were significantly lower than those of the controls" circulation_biomarker_diagnosis_down hsa-mir-5100 "Leukemia, Lymphoblastic, Acute, Childhood" 28910942 "The expression levels of let-7f-5p, miR-5100 and miR-25-3p in the cALL patients were significantly lower than those of the controls" circulation_biomarker_diagnosis_down hsa-mir-126 Coronary Artery Disease 29062343 miR-126 expression was significantly down-regulated in the circulation of CAD patients compared with control subjects circulation_biomarker_diagnosis_down hsa-mir-18a "Leukemia, Lymphoblastic, Acute" 29068867 Low Expression of miR-18a as a Characteristic of Pediatric Acute Lymphoblastic Leukemia. circulation_biomarker_diagnosis_down hsa-mir-21 "Diabetes Mellitus, Type 2" 29113498 Decreased serum microRNA-21 level is associated with obesity in healthy and type 2 diabetic subjects. circulation_biomarker_diagnosis_down hsa-mir-638 "Carcinoma, Hepatocellular" 29278659 Decreased levels of serum exosomal miR-638 predict poor prognosis in hepatocellular carcinoma. circulation_biomarker_diagnosis_down hsa-mir-133a Myocardial Infarction 29324314 Down-regulation of miR-133a/b in patients with myocardial infarction correlates with the presence of ventricular fibrillation circulation_biomarker_diagnosis_down hsa-mir-133b Myocardial Infarction 29324314 Down-regulation of miR-133a/b in patients with myocardial infarction correlates with the presence of ventricular fibrillation circulation_biomarker_diagnosis_down hsa-mir-222 Preeclampsia 29381395 serum miR-222 expression levels showed a significant decrease in PE compared to GH and normotensive groups circulation_biomarker_diagnosis_down hsa-mir-34a Pulmonary Hypertension 29431643 Circulatory miR-34a-3p expression is decreased in both patients with PAH and preclinical models of PAH circulation_biomarker_diagnosis_down hsa-mir-204 Frontotemporal Dementia 29434051 Downregulation of exosomal miR-204-5p and miR-632 as a biomarker for FTD: a GENFI study. circulation_biomarker_diagnosis_down hsa-mir-632 Frontotemporal Dementia 29434051 Downregulation of exosomal miR-204-5p and miR-632 as a biomarker for FTD: a GENFI study. circulation_biomarker_diagnosis_down hsa-mir-17 Myocardial Infarction 29536180 Downregulation of microRNA-17-5p improves cardiac function after myocardial infarction via attenuation of apoptosis in endothelial cells. circulation_biomarker_diagnosis_down hsa-mir-20a "Diabetes Mellitus, Gestational" 29556924 Decreased Expression of Circulating miR-20a-5p in South African Women with Gestational Diabetes Mellitus. circulation_biomarker_diagnosis_down hsa-mir-221 Colorectal Carcinoma 29630521 "Following the overexpression of GAS5, the GAS5expressions was up-regulated and miR-221 expression was down-regulated; the rate of cell proliferation, migration and invasion were decreased" circulation_biomarker_diagnosis_down hsa-mir-29a Spinal Stenosis 29749498 Detection of miR?29a in plasma of patients with lumbar spinal stenosis and the clinical significance. circulation_biomarker_diagnosis_down hsa-let-7d Familial Mediterranean Fever 29787577 "four miRNAs were upregulated (miR-144-3p, miR-21-5p, miR-4454, and miR-451a), and three were downregulated (miR-107, let-7d-5p, and miR-148b-3p)" circulation_biomarker_diagnosis_down hsa-mir-107 Familial Mediterranean Fever 29787577 "four miRNAs were upregulated (miR-144-3p, miR-21-5p, miR-4454, and miR-451a), and three were downregulated (miR-107, let-7d-5p, and miR-148b-3p)" circulation_biomarker_diagnosis_down hsa-mir-148b Familial Mediterranean Fever 29787577 "four miRNAs were upregulated (miR-144-3p, miR-21-5p, miR-4454, and miR-451a), and three were downregulated (miR-107, let-7d-5p, and miR-148b-3p)" circulation_biomarker_diagnosis_down hsa-mir-122 Preeclampsia 29800045 "Circulating levels of miR-126-3p, -146a-5p, and -122-5p were significantly decreased in women with premature ACS who reported prior PE compared to those with prior normotensive pregnancy" circulation_biomarker_diagnosis_down hsa-mir-126 Preeclampsia 29800045 "Circulating levels of miR-126-3p, -146a-5p, and -122-5p were significantly decreased in women with premature ACS who reported prior PE compared to those with prior normotensive pregnancy" circulation_biomarker_diagnosis_down hsa-mir-146a Preeclampsia 29800045 "Circulating levels of miR-126-3p, -146a-5p, and -122-5p were significantly decreased in women with premature ACS who reported prior PE compared to those with prior normotensive pregnancy" circulation_biomarker_diagnosis_down hsa-mir-1246 Systemic Lupus Erythematosus 29873187 "Although the levels of many miRNAs were unaffected after passage through the plasma adsorption membrane, expression of some miRNAs, including miR-1246, miR-4732-5p, and miR-6088 are declined" circulation_biomarker_diagnosis_down hsa-mir-4732 Systemic Lupus Erythematosus 29873187 "Although the levels of many miRNAs were unaffected after passage through the plasma adsorption membrane, expression of some miRNAs, including miR-1246, miR-4732-5p, and miR-6088 are declined" circulation_biomarker_diagnosis_down hsa-mir-6088 Systemic Lupus Erythematosus 29873187 "Although the levels of many miRNAs were unaffected after passage through the plasma adsorption membrane, expression of some miRNAs, including miR-1246, miR-4732-5p, and miR-6088 are declined" circulation_biomarker_diagnosis_down hsa-mir-194 Traumatic Brain Injury 29873258 miR-300-3p and miR-598-3p increased while miR-450-3p and miR-194-5p significantly decreased following TBI circulation_biomarker_diagnosis_down hsa-mir-450 Traumatic Brain Injury 29873258 miR-300-3p and miR-598-3p increased while miR-450-3p and miR-194-5p significantly decreased following TBI circulation_biomarker_diagnosis_down hsa-mir-128 Systemic Lupus Erythematosus 29873766 "miR-361-5p, miR-128-3p and miR-181a-2-3p expression was lower in patients with a high IFN signature (false discovery rate <0.05) as compared with patients with a low IFN signature and HCs." circulation_biomarker_diagnosis_down hsa-mir-181a Systemic Lupus Erythematosus 29873766 "miR-361-5p, miR-128-3p and miR-181a-2-3p expression was lower in patients with a high IFN signature (false discovery rate <0.05) as compared with patients with a low IFN signature and HCs." circulation_biomarker_diagnosis_down hsa-mir-361 Systemic Lupus Erythematosus 29873766 "miR-361-5p, miR-128-3p and miR-181a-2-3p expression was lower in patients with a high IFN signature (false discovery rate <0.05) as compared with patients with a low IFN signature and HCs." circulation_biomarker_diagnosis_down hsa-mir-142 Acute Lung Injury 29904430 "9 miRNAs were significantly upregulated (miR-1843-3p, miR-323-3p, miR-183-5p, miR-182 and miR-196b-3p) or downregulated (miR-547-3p, miR-301b-5p, miR-503-3p and miR-142-3p)" circulation_biomarker_diagnosis_down hsa-mir-301b Acute Lung Injury 29904430 "9 miRNAs were significantly upregulated (miR-1843-3p, miR-323-3p, miR-183-5p, miR-182 and miR-196b-3p) or downregulated (miR-547-3p, miR-301b-5p, miR-503-3p and miR-142-3p)" circulation_biomarker_diagnosis_down hsa-mir-503 Acute Lung Injury 29904430 "9 miRNAs were significantly upregulated (miR-1843-3p, miR-323-3p, miR-183-5p, miR-182 and miR-196b-3p) or downregulated (miR-547-3p, miR-301b-5p, miR-503-3p and miR-142-3p)" circulation_biomarker_diagnosis_down hsa-mir-547 Acute Lung Injury 29904430 "9 miRNAs were significantly upregulated (miR-1843-3p, miR-323-3p, miR-183-5p, miR-182 and miR-196b-3p) or downregulated (miR-547-3p, miR-301b-5p, miR-503-3p and miR-142-3p)" circulation_biomarker_diagnosis_down hsa-mir-141 Parkinson Disease 29935433 "We identified differential expression of 10 miRNA of which 5 were upregulated in PD (miR-9-5p, miR-135a-5p, miR-135b-5p, miR-449a, and miR-449b-5p) and 5 downregulated (miR-141-3p, miR-199a-5p, miR-299-5p, miR-518e-3p, and miR-519a-3p)" circulation_biomarker_diagnosis_down hsa-mir-199a Parkinson Disease 29935433 "We identified differential expression of 10 miRNA of which 5 were upregulated in PD (miR-9-5p, miR-135a-5p, miR-135b-5p, miR-449a, and miR-449b-5p) and 5 downregulated (miR-141-3p, miR-199a-5p, miR-299-5p, miR-518e-3p, and miR-519a-3p)" circulation_biomarker_diagnosis_down hsa-mir-299 Parkinson Disease 29935433 "We identified differential expression of 10 miRNA of which 5 were upregulated in PD (miR-9-5p, miR-135a-5p, miR-135b-5p, miR-449a, and miR-449b-5p) and 5 downregulated (miR-141-3p, miR-199a-5p, miR-299-5p, miR-518e-3p, and miR-519a-3p)" circulation_biomarker_diagnosis_down hsa-mir-518e Parkinson Disease 29935433 "We identified differential expression of 10 miRNA of which 5 were upregulated in PD (miR-9-5p, miR-135a-5p, miR-135b-5p, miR-449a, and miR-449b-5p) and 5 downregulated (miR-141-3p, miR-199a-5p, miR-299-5p, miR-518e-3p, and miR-519a-3p)" circulation_biomarker_diagnosis_down hsa-mir-519a Parkinson Disease 29935433 "We identified differential expression of 10 miRNA of which 5 were upregulated in PD (miR-9-5p, miR-135a-5p, miR-135b-5p, miR-449a, and miR-449b-5p) and 5 downregulated (miR-141-3p, miR-199a-5p, miR-299-5p, miR-518e-3p, and miR-519a-3p)" circulation_biomarker_diagnosis_down hsa-mir-151a Lupus Nephritis 29998838 Down-regulation of serum miR-151a-3p is associated with renal tissue activity in class IV lupus nephritis. circulation_biomarker_diagnosis_down hsa-mir-15b Systemic Lupus Erythematosus 30008716 "the downregulated expression of miR-19b, miR-25, miR-93, and miR-15b was associated with SLE disease activity (P?0.7, including miR-24, miR-134, miR-146a, miR-378, miR-484, miR-628-3p, and miR-1825." circulation_biomarker_diagnosis_ns hsa-mir-146a Pancreatic Neoplasms 23697990 "Several other circulating miRNAs distinguished sera of patients with pancreatic cancer from those of healthy controls with AUCs >0.7, including miR-24, miR-134, miR-146a, miR-378, miR-484, miR-628-3p, and miR-1825." circulation_biomarker_diagnosis_ns hsa-mir-1825 Pancreatic Neoplasms 23697990 "Several other circulating miRNAs distinguished sera of patients with pancreatic cancer from those of healthy controls with AUCs >0.7, including miR-24, miR-134, miR-146a, miR-378, miR-484, miR-628-3p, and miR-1825." circulation_biomarker_diagnosis_ns hsa-mir-24 Pancreatic Neoplasms 23697990 "Several other circulating miRNAs distinguished sera of patients with pancreatic cancer from those of healthy controls with AUCs >0.7, including miR-24, miR-134, miR-146a, miR-378, miR-484, miR-628-3p, and miR-1825." circulation_biomarker_diagnosis_ns hsa-mir-378 Pancreatic Neoplasms 23697990 "Several other circulating miRNAs distinguished sera of patients with pancreatic cancer from those of healthy controls with AUCs >0.7, including miR-24, miR-134, miR-146a, miR-378, miR-484, miR-628-3p, and miR-1825." circulation_biomarker_diagnosis_ns hsa-mir-484 Pancreatic Neoplasms 23697990 "Several other circulating miRNAs distinguished sera of patients with pancreatic cancer from those of healthy controls with AUCs >0.7, including miR-24, miR-134, miR-146a, miR-378, miR-484, miR-628-3p, and miR-1825." circulation_biomarker_diagnosis_ns hsa-mir-628 Pancreatic Neoplasms 23697990 "Several other circulating miRNAs distinguished sera of patients with pancreatic cancer from those of healthy controls with AUCs >0.7, including miR-24, miR-134, miR-146a, miR-378, miR-484, miR-628-3p, and miR-1825." circulation_biomarker_diagnosis_ns hsa-mir-122 "Carcinoma, Hepatocellular" 23723713 Circulating microRNA-122a as a diagnostic marker for hepatocellular carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-199a-1 Gastric Neoplasms 23733518 MiRNA-199a-3p: A Potential Circulating Diagnostic Biomarker for Early Gastric Cancer. circulation_biomarker_diagnosis_ns hsa-mir-199a-2 Gastric Neoplasms 23733518 MiRNA-199a-3p: A Potential Circulating Diagnostic Biomarker for Early Gastric Cancer. circulation_biomarker_diagnosis_ns hsa-mir-145 Heart Failure 23736534 "Changed circulating miRNA-26b-5p, miRNA-145-5p, miRNA-92a-3p, miRNA-30e-5p, and miRNA-29a-3p" circulation_biomarker_diagnosis_ns hsa-mir-26b Heart Failure 23736534 "Changed circulating miRNA-26b-5p, miRNA-145-5p, miRNA-92a-3p, miRNA-30e-5p, and miRNA-29a-3p" circulation_biomarker_diagnosis_ns hsa-mir-29a Heart Failure 23736534 "Changed circulating miRNA-26b-5p, miRNA-145-5p, miRNA-92a-3p, miRNA-30e-5p, and miRNA-29a-3p" circulation_biomarker_diagnosis_ns hsa-mir-30e Heart Failure 23736534 "Changed circulating miRNA-26b-5p, miRNA-145-5p, miRNA-92a-3p, miRNA-30e-5p, and miRNA-29a-3p" circulation_biomarker_diagnosis_ns hsa-mir-92a-1 Heart Failure 23736534 "Changed circulating miRNA-26b-5p, miRNA-145-5p, miRNA-92a-3p, miRNA-30e-5p, and miRNA-29a-3p" circulation_biomarker_diagnosis_ns hsa-mir-92a-2 Heart Failure 23736534 "Changed circulating miRNA-26b-5p, miRNA-145-5p, miRNA-92a-3p, miRNA-30e-5p, and miRNA-29a-3p" circulation_biomarker_diagnosis_ns hsa-mir-1-1 Myocardial Infarction 23747779 "Circulating miR-1, miR-208a, and miR-133a continuously rose during the first 4 h after induction of AMI." circulation_biomarker_diagnosis_ns hsa-mir-1-2 Myocardial Infarction 23747779 "Circulating miR-1, miR-208a, and miR-133a continuously rose during the first 4 h after induction of AMI." circulation_biomarker_diagnosis_ns hsa-mir-133a-1 Myocardial Infarction 23747779 "Circulating miR-1, miR-208a, and miR-133a continuously rose during the first 4 h after induction of AMI." circulation_biomarker_diagnosis_ns hsa-mir-133a-2 Myocardial Infarction 23747779 "Circulating miR-1, miR-208a, and miR-133a continuously rose during the first 4 h after induction of AMI." circulation_biomarker_diagnosis_ns hsa-mir-208a Myocardial Infarction 23747779 "Circulating miR-1, miR-208a, and miR-133a continuously rose during the first 4 h after induction of AMI." circulation_biomarker_diagnosis_ns hsa-mir-155 Breast Neoplasms 23748853 "Deregulated Serum Concentrations of Circulating Cell-Free MicroRNAs miR-17, miR-34a, miR-155, and miR-373 in Human Breast Cancer Development and Progression." circulation_biomarker_diagnosis_ns hsa-mir-17 Breast Neoplasms 23748853 "Deregulated Serum Concentrations of Circulating Cell-Free MicroRNAs miR-17, miR-34a, miR-155, and miR-373 in Human Breast Cancer Development and Progression." circulation_biomarker_diagnosis_ns hsa-mir-34a Breast Neoplasms 23748853 "Deregulated Serum Concentrations of Circulating Cell-Free MicroRNAs miR-17, miR-34a, miR-155, and miR-373 in Human Breast Cancer Development and Progression." circulation_biomarker_diagnosis_ns hsa-mir-373 Breast Neoplasms 23748853 "Deregulated Serum Concentrations of Circulating Cell-Free MicroRNAs miR-17, miR-34a, miR-155, and miR-373 in Human Breast Cancer Development and Progression." circulation_biomarker_diagnosis_ns hsa-mir-10a "Carcinoma, Lung, Non-Small-Cell" 23756108 "Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed" circulation_biomarker_diagnosis_ns hsa-mir-126 "Carcinoma, Lung, Non-Small-Cell" 23756108 "Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed" circulation_biomarker_diagnosis_ns hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 23756108 "Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed" circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 23756108 "Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed" circulation_biomarker_diagnosis_ns hsa-mir-30d "Carcinoma, Lung, Non-Small-Cell" 23756108 "Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed" circulation_biomarker_diagnosis_ns hsa-mir-30e "Carcinoma, Lung, Non-Small-Cell" 23756108 "Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed" circulation_biomarker_diagnosis_ns hsa-mir-451a "Carcinoma, Lung, Non-Small-Cell" 23756108 "Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed" circulation_biomarker_diagnosis_ns hsa-mir-451b "Carcinoma, Lung, Non-Small-Cell" 23756108 "Plasma miR-21, miR-30d, miR-451, miR-10a, miR-30e-5p and miR-126*, miR-126, miR-145) were differentially expressed" circulation_biomarker_diagnosis_ns hsa-mir-195 "Carcinoma, Adrenocortical" 23756429 Serum miR-483-5p and miR-195 are predictive of recurrence risk in adrenocortical cancer patients. circulation_biomarker_diagnosis_ns hsa-mir-483 "Carcinoma, Adrenocortical" 23756429 Serum miR-483-5p and miR-195 are predictive of recurrence risk in adrenocortical cancer patients. circulation_biomarker_diagnosis_ns hsa-mir-145 Multiple Sclerosis 23773985 "RRMS patients in remission had altered expression of mirNAs. We validated mir-145 as a potential diagnostic biomarker for the diagnosis of MS in blood, plasma and serum." circulation_biomarker_diagnosis_ns hsa-mir-27a Pancreatic Neoplasms 23782250 Combined serum CA19-9 and miR-27a-3p in peripheral blood mononuclear cells to diagnose pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-424 Fragile X Syndrome 23790110 MicroRNA expression profiling in blood from fragile X-associated tremor/ataxia syndrome patients. circulation_biomarker_diagnosis_ns hsa-mir-574 Fragile X Syndrome 23790110 MicroRNA expression profiling in blood from fragile X-associated tremor/ataxia syndrome patients. circulation_biomarker_diagnosis_ns hsa-mir-1246 Early-Stage Cervical Squamous Cell Carcinoma 23799609 Serum microRNA expression levels can predict lymph node metastasis in patients with early-stage cervical squamous cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-20a Early-Stage Cervical Squamous Cell Carcinoma 23799609 Serum microRNA expression levels can predict lymph node metastasis in patients with early-stage cervical squamous cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-2392 Early-Stage Cervical Squamous Cell Carcinoma 23799609 Serum microRNA expression levels can predict lymph node metastasis in patients with early-stage cervical squamous cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-3162 Early-Stage Cervical Squamous Cell Carcinoma 23799609 Serum microRNA expression levels can predict lymph node metastasis in patients with early-stage cervical squamous cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-4484 Early-Stage Cervical Squamous Cell Carcinoma 23799609 Serum microRNA expression levels can predict lymph node metastasis in patients with early-stage cervical squamous cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-106b Gastric Neoplasms 23806809 Validation of circulating miRNA biomarkers for predicting lymph node metastasis in gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-146a Gastric Neoplasms 23806809 Validation of circulating miRNA biomarkers for predicting lymph node metastasis in gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-148a Gastric Neoplasms 23806809 Validation of circulating miRNA biomarkers for predicting lymph node metastasis in gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-21 Gastric Neoplasms 23806809 Validation of circulating miRNA biomarkers for predicting lymph node metastasis in gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-223 Gastric Neoplasms 23806809 Validation of circulating miRNA biomarkers for predicting lymph node metastasis in gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-27a Gastric Neoplasms 23806809 Validation of circulating miRNA biomarkers for predicting lymph node metastasis in gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-433 Gastric Neoplasms 23806809 Validation of circulating miRNA biomarkers for predicting lymph node metastasis in gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-1 "Carcinoma, Hepatocellular" 23810247 Our data indicate that serum miR-1 is a new independent parameter of OS in HCC patients and may therefore improve the predictive value of classical HCC staging scores. circulation_biomarker_diagnosis_ns hsa-mir-122 "Carcinoma, Hepatocellular" 23810247 Our data indicate that serum miR-1 is a new independent parameter of OS in HCC patients and may therefore improve the predictive value of classical HCC staging scores. circulation_biomarker_diagnosis_ns hsa-mir-122 Chronic Obstructive Pulmonary Disease 23814167 Plasma levels of individual myomiRs are altered in patients with COPD but alone do not predict muscle fibre size or proportion. Our findings are consistent with an increase in muscle wasting and turnover associated with the development of skeletal muscle dysfunction and fibre-type shift in patients with stable COPD. circulation_biomarker_diagnosis_ns hsa-mir-16 Chronic Obstructive Pulmonary Disease 23814167 Plasma levels of individual myomiRs are altered in patients with COPD but alone do not predict muscle fibre size or proportion. Our findings are consistent with an increase in muscle wasting and turnover associated with the development of skeletal muscle dysfunction and fibre-type shift in patients with stable COPD. circulation_biomarker_diagnosis_ns hsa-mir-107 Pancreatic Neoplasms 23834149 "At last, we have also explained the role of miRNAs in diagnostic marker (miR- 200, miR-21, miR-103, miR-107, and miR-155) and as a therapeutic modulator (miR-34, miR-21, miR-221, and miR-101) in pancreatic cancer." circulation_biomarker_diagnosis_ns hsa-mir-29c Colorectal Carcinoma 23840538 "miRNA-29c shows anti-tumorigenesis activity, and preoperative circulating miRNA-29c levels can be used to predict postoperative early relapse of CRC." circulation_biomarker_diagnosis_ns hsa-mir-145 Stroke 23860376 Serum miR-145 was not detected in over 50% of the patients and it may not be an ideal marker to predict stroke. MiR-21 and miR-221 are novel biomarkers for atherosclerosis and stroke. circulation_biomarker_diagnosis_ns hsa-mir-221 Stroke 23860376 Serum miR-145 was not detected in over 50% of the patients and it may not be an ideal marker to predict stroke. MiR-21 and miR-221 are novel biomarkers for atherosclerosis and stroke. circulation_biomarker_diagnosis_ns hsa-mir-145 Melanoma 23863473 Sensitive detection of melanoma metastasis using circulating microRNA expression profiles. circulation_biomarker_diagnosis_ns hsa-mir-150 Melanoma 23863473 Sensitive detection of melanoma metastasis using circulating microRNA expression profiles. circulation_biomarker_diagnosis_ns hsa-mir-155 Melanoma 23863473 Sensitive detection of melanoma metastasis using circulating microRNA expression profiles. circulation_biomarker_diagnosis_ns hsa-mir-203 Melanoma 23863473 Sensitive detection of melanoma metastasis using circulating microRNA expression profiles. circulation_biomarker_diagnosis_ns hsa-mir-205 Melanoma 23863473 Sensitive detection of melanoma metastasis using circulating microRNA expression profiles. circulation_biomarker_diagnosis_ns hsa-mir-9 Melanoma 23863473 Sensitive detection of melanoma metastasis using circulating microRNA expression profiles. circulation_biomarker_diagnosis_ns hsa-mir-130b Metabolic Syndrome 23868745 Circulating miR-130b reflects the degree of obesity and could serve as a potential biomarker for hypertriacylglycerolaemia and metabolic syndrome. Circulating miR-130b could function as a metabolic mediator for adipose muscle crosstalk and might be involved in the pathogenesis of obesity associated metabolic diseases. circulation_biomarker_diagnosis_ns hsa-mir-106b Neoplasms [unspecific] 23874370 Principal component analysis based feature extraction approach to identify circulating microRNA biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-140 Neoplasms [unspecific] 23874370 Principal component analysis based feature extraction approach to identify circulating microRNA biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-15b Neoplasms [unspecific] 23874370 Principal component analysis based feature extraction approach to identify circulating microRNA biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-16 Neoplasms [unspecific] 23874370 Principal component analysis based feature extraction approach to identify circulating microRNA biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-185 Neoplasms [unspecific] 23874370 Principal component analysis based feature extraction approach to identify circulating microRNA biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-191 Neoplasms [unspecific] 23874370 Principal component analysis based feature extraction approach to identify circulating microRNA biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-19b Neoplasms [unspecific] 23874370 Principal component analysis based feature extraction approach to identify circulating microRNA biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-30d Neoplasms [unspecific] 23874370 Principal component analysis based feature extraction approach to identify circulating microRNA biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-320a Neoplasms [unspecific] 23874370 Principal component analysis based feature extraction approach to identify circulating microRNA biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-425 Neoplasms [unspecific] 23874370 Principal component analysis based feature extraction approach to identify circulating microRNA biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-486 Neoplasms [unspecific] 23874370 Principal component analysis based feature extraction approach to identify circulating microRNA biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-92a Neoplasms [unspecific] 23874370 Principal component analysis based feature extraction approach to identify circulating microRNA biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-125a Rheumatoid Arthritis 23874885 Comprehensive microRNA analysis identifies miR-24 and miR-125a-5p as plasma biomarkers for rheumatoid arthritis. circulation_biomarker_diagnosis_ns hsa-mir-24 Rheumatoid Arthritis 23874885 Comprehensive microRNA analysis identifies miR-24 and miR-125a-5p as plasma biomarkers for rheumatoid arthritis. circulation_biomarker_diagnosis_ns hsa-mir-125b Machado-Joseph Disease 23879331 MicroRNA profiling in the serums of SCA3/MJD patients. circulation_biomarker_diagnosis_ns hsa-mir-25 Machado-Joseph Disease 23879331 MicroRNA profiling in the serums of SCA3/MJD patients. circulation_biomarker_diagnosis_ns hsa-mir-29a Machado-Joseph Disease 23879331 MicroRNA profiling in the serums of SCA3/MJD patients. circulation_biomarker_diagnosis_ns hsa-mir-34b Machado-Joseph Disease 23879331 MicroRNA profiling in the serums of SCA3/MJD patients. circulation_biomarker_diagnosis_ns hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 23881177 "Relative expressions of miR-205-5p, miR-205-3p, and miR-21 in tissues and serum of non-small cell lung cancer patients." circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 23881177 "Relative expressions of miR-205-5p, miR-205-3p, and miR-21 in tissues and serum of non-small cell lung cancer patients." circulation_biomarker_diagnosis_ns hsa-mir-16 Liver Diseases [unspecific] 23886700 Incubation of whole blood at room temperature does not alter the plasma concentrations of microRNA-16 and -223. circulation_biomarker_diagnosis_ns hsa-mir-223 Liver Diseases [unspecific] 23886700 Incubation of whole blood at room temperature does not alter the plasma concentrations of microRNA-16 and -223. circulation_biomarker_diagnosis_ns hsa-let-7d Alzheimer Disease 23922807 Circulating miRNA biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-let-7g Alzheimer Disease 23922807 Circulating miRNA biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-142 Alzheimer Disease 23922807 Circulating miRNA biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-15b Alzheimer Disease 23922807 Circulating miRNA biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-191 Alzheimer Disease 23922807 Circulating miRNA biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-301a Alzheimer Disease 23922807 Circulating miRNA biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-545 Alzheimer Disease 23922807 Circulating miRNA biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-122 Metabolic Syndrome 23922812 These findings cast new light on the regulation of miR-33a and miR-122 in a dyslipidemic model of obese rats and the way these miRNAs are modulated by dietary components in the liver and in PBMCs. circulation_biomarker_diagnosis_ns hsa-mir-33a Metabolic Syndrome 23922812 These findings cast new light on the regulation of miR-33a and miR-122 in a dyslipidemic model of obese rats and the way these miRNAs are modulated by dietary components in the liver and in PBMCs. circulation_biomarker_diagnosis_ns hsa-mir-141 Prostate Neoplasms 23935962 Circulating microRNA profiling identifies a subset of metastatic prostate cancer patients with evidence of cancer-associated hypoxia. circulation_biomarker_diagnosis_ns hsa-mir-200a Prostate Neoplasms 23935962 Circulating microRNA profiling identifies a subset of metastatic prostate cancer patients with evidence of cancer-associated hypoxia. circulation_biomarker_diagnosis_ns hsa-mir-200c Prostate Neoplasms 23935962 Circulating microRNA profiling identifies a subset of metastatic prostate cancer patients with evidence of cancer-associated hypoxia. circulation_biomarker_diagnosis_ns hsa-mir-210 Prostate Neoplasms 23935962 Circulating microRNA profiling identifies a subset of metastatic prostate cancer patients with evidence of cancer-associated hypoxia. circulation_biomarker_diagnosis_ns hsa-mir-375 Prostate Neoplasms 23935962 Circulating microRNA profiling identifies a subset of metastatic prostate cancer patients with evidence of cancer-associated hypoxia. circulation_biomarker_diagnosis_ns hsa-mir-124 Glioma 23936026 These results suggest that miR-124 may function as anti-migration and anti-invasion influence in glioma and provides a potential approach for developing miR-124-based therapeutic strategies for malignant glioma therapy. circulation_biomarker_diagnosis_ns hsa-mir-133a Aortic Stenosis 23948643 "Preoperative plasma levels of miR-133a reflect their myocardial pression and predict the regression potential of LV hypertrophy after AVR. The value of this bedside information for the surgical timing, particularly in asymptomatic aortic stenosis patients, deserves confirmation in further clinical studies." circulation_biomarker_diagnosis_ns hsa-mir-92 Ovary Mixed Epithelial Carcinoma 23963852 The detection of miR-92 levels in the serum might serve as a new tumour biomarker in the diagnosis and assessment of prognosis of EOC. circulation_biomarker_diagnosis_ns hsa-mir-193b Leukemia 23998571 MicroRNA-193b expression in newly diagnosed leukemia patients and its significance. circulation_biomarker_diagnosis_ns hsa-mir-139 Colorectal Carcinoma 24022433 "Plasma miRNAs are reliable, noninvasive, and inexpensive markers for CR adenomas. This miRNA panel warrants study in larger cohorts. Plasma-based assays could provide better screening compliance compared to fecal occult blood or endoscopic screening." circulation_biomarker_diagnosis_ns hsa-mir-142 Colorectal Carcinoma 24022433 "Plasma miRNAs are reliable, noninvasive, and inexpensive markers for CR adenomas. This miRNA panel warrants study in larger cohorts. Plasma-based assays could provide better screening compliance compared to fecal occult blood or endoscopic screening." circulation_biomarker_diagnosis_ns hsa-mir-15b Colorectal Carcinoma 24022433 "Plasma miRNAs are reliable, noninvasive, and inexpensive markers for CR adenomas. This miRNA panel warrants study in larger cohorts. Plasma-based assays could provide better screening compliance compared to fecal occult blood or endoscopic screening." circulation_biomarker_diagnosis_ns hsa-mir-431 Colorectal Carcinoma 24022433 "Plasma miRNAs are reliable, noninvasive, and inexpensive markers for CR adenomas. This miRNA panel warrants study in larger cohorts. Plasma-based assays could provide better screening compliance compared to fecal occult blood or endoscopic screening." circulation_biomarker_diagnosis_ns hsa-mir-532 Colorectal Carcinoma 24022433 "Plasma miRNAs are reliable, noninvasive, and inexpensive markers for CR adenomas. This miRNA panel warrants study in larger cohorts. Plasma-based assays could provide better screening compliance compared to fecal occult blood or endoscopic screening." circulation_biomarker_diagnosis_ns hsa-mir-652 Colorectal Carcinoma 24022433 "Plasma miRNAs are reliable, noninvasive, and inexpensive markers for CR adenomas. This miRNA panel warrants study in larger cohorts. Plasma-based assays could provide better screening compliance compared to fecal occult blood or endoscopic screening." circulation_biomarker_diagnosis_ns hsa-mir-16 "Carcinoma, Nasopharyngeal" 24025417 "plasma miRNA expression is a useful biomarker for NPC diagnosis but not for its prognosis. More importantly, it is simple, effective, and non-invasive. Combination of several plasma miRNAs can increase both NPC diagnostic sensitivity and specificity. miR-329,hsa-mir-487b,hsa-mir-494,hsa-mir-495" circulation_biomarker_diagnosis_ns hsa-mir-210 Preeclampsia 24035613 "Hence, we conclude that aberrant expression of miR-210 may contribute to trophoblast function and that miR-210 is a novel predictive serum biomarker for preeclampsia that can help in identifying at-risk women for monitoring and treatment." circulation_biomarker_diagnosis_ns hsa-mir-155 Graft-Versus-Host Disease 24041574 Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease. circulation_biomarker_diagnosis_ns hsa-mir-199a Graft-Versus-Host Disease 24041574 Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease. circulation_biomarker_diagnosis_ns hsa-mir-30a Graft-Versus-Host Disease 24041574 Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease. circulation_biomarker_diagnosis_ns hsa-mir-377 Graft-Versus-Host Disease 24041574 Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease. circulation_biomarker_diagnosis_ns hsa-mir-423 Graft-Versus-Host Disease 24041574 Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease. circulation_biomarker_diagnosis_ns hsa-mir-93 Graft-Versus-Host Disease 24041574 Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease. circulation_biomarker_diagnosis_ns hsa-mir-133a Acute Myocardial Infarction 24053180 Circulating miR-133a may be a new biomarker for AMI and as a potential diagnostic tool. And increased miR-133a level may be used to predict both the presence and severity of coronary lesions in CHD patients. circulation_biomarker_diagnosis_ns hsa-mir-210 "Carcinoma, Lung, Non-Small-Cell" 24065453 These findings suggest that serum miR-210 levels might be a novel diagnostic and prognostic marker of NSCLC. circulation_biomarker_diagnosis_ns hsa-mir-135a "Leukemia, Myeloid, Acute" 24072101 "miR-409-3p, miR-135a, miR-196b and mir-644 arose as prognostic markers for IR-AML, both overall and within specific molecular subgroups." circulation_biomarker_diagnosis_ns hsa-mir-196b "Leukemia, Myeloid, Acute" 24072101 "miR-409-3p, miR-135a, miR-196b and mir-644 arose as prognostic markers for IR-AML, both overall and within specific molecular subgroups." circulation_biomarker_diagnosis_ns hsa-mir-409 "Leukemia, Myeloid, Acute" 24072101 "miR-409-3p, miR-135a, miR-196b and mir-644 arose as prognostic markers for IR-AML, both overall and within specific molecular subgroups." circulation_biomarker_diagnosis_ns hsa-mir-644 "Leukemia, Myeloid, Acute" 24072101 "miR-409-3p, miR-135a, miR-196b and mir-644 arose as prognostic markers for IR-AML, both overall and within specific molecular subgroups." circulation_biomarker_diagnosis_ns hsa-mir-122 Liver Injury 24086271 "serum miR-122 has strong potential as a novel, specific and noninvasive biomarker for diagnosis of cholestasis-induced liver injury." circulation_biomarker_diagnosis_ns hsa-mir-21 Biliary Tract Neoplasms 24118467 "Plasma miR-21 is a novel diagnostic biomarker for BTC, and may be useful in distinguishing between BTC and BBD patients." circulation_biomarker_diagnosis_ns hsa-mir-15b Peripheral Vascular Disease 24129591 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses.miR-16, miR-363, and miR-15b had the best predictive values" circulation_biomarker_diagnosis_ns hsa-mir-16 Peripheral Vascular Disease 24129591 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses.miR-16, miR-363, and miR-15b had the best predictive values" circulation_biomarker_diagnosis_ns hsa-mir-363 Peripheral Vascular Disease 24129591 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses.miR-16, miR-363, and miR-15b had the best predictive values" circulation_biomarker_diagnosis_ns hsa-mir-126 Peripheral Vascular Disease 24129592 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses." circulation_biomarker_diagnosis_ns hsa-mir-15b Peripheral Vascular Disease 24129592 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses." circulation_biomarker_diagnosis_ns hsa-mir-16 Peripheral Vascular Disease 24129592 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses." circulation_biomarker_diagnosis_ns hsa-mir-181a-2 Peripheral Vascular Disease 24129592 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses." circulation_biomarker_diagnosis_ns hsa-mir-195 Peripheral Vascular Disease 24129592 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses." circulation_biomarker_diagnosis_ns hsa-mir-20b Peripheral Vascular Disease 24129592 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses." circulation_biomarker_diagnosis_ns hsa-mir-25 Peripheral Vascular Disease 24129592 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses." circulation_biomarker_diagnosis_ns hsa-mir-26b Peripheral Vascular Disease 24129592 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses." circulation_biomarker_diagnosis_ns hsa-mir-27b Peripheral Vascular Disease 24129592 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses." circulation_biomarker_diagnosis_ns hsa-mir-28 Peripheral Vascular Disease 24129592 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses." circulation_biomarker_diagnosis_ns hsa-mir-335 Peripheral Vascular Disease 24129592 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses." circulation_biomarker_diagnosis_ns hsa-mir-363 Peripheral Vascular Disease 24129592 "A 12-miRNA PAD-specific signature, which includes let 7e, miR-15b, -16, -20b, -25, -26b,-27b, -28-5p, -126, -195, -335, and -363, was further investigated and validated in 2 additional sample sets. Each of these 12 miRNAs exhibited good diagnostic value as evidenced by receiver operating characteristic curve analyses." circulation_biomarker_diagnosis_ns hsa-mir-423 Hereditary Breast Carcinoma 24129975 miR-4417 and miR-423-3p expressions differentiated 70.1 % of hereditary and non-hereditary BCs. Array miR expression profiles can differentiate the four study groups using FFPE BC. circulation_biomarker_diagnosis_ns hsa-mir-4417 Hereditary Breast Carcinoma 24129975 miR-4417 and miR-423-3p expressions differentiated 70.1 % of hereditary and non-hereditary BCs. Array miR expression profiles can differentiate the four study groups using FFPE BC. circulation_biomarker_diagnosis_ns hsa-mir-19a "Squamous Cell Carcinoma, Lung" 24130905 "Tumor cells secrete miRNA-containing exosomes into circulation, and that miRNA profiling of the exosomal plasma fraction may reveal powerful cancer biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-19b "Squamous Cell Carcinoma, Lung" 24130905 "Tumor cells secrete miRNA-containing exosomes into circulation, and that miRNA profiling of the exosomal plasma fraction may reveal powerful cancer biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-205 "Squamous Cell Carcinoma, Lung" 24130905 "Tumor cells secrete miRNA-containing exosomes into circulation, and that miRNA profiling of the exosomal plasma fraction may reveal powerful cancer biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-20a "Squamous Cell Carcinoma, Lung" 24130905 "Tumor cells secrete miRNA-containing exosomes into circulation, and that miRNA profiling of the exosomal plasma fraction may reveal powerful cancer biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-30b "Squamous Cell Carcinoma, Lung" 24130905 "Tumor cells secrete miRNA-containing exosomes into circulation, and that miRNA profiling of the exosomal plasma fraction may reveal powerful cancer biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-125b Alzheimer Disease 24139697 Our results indicate that serum miR-125b may serve as a useful noninvasive biomarker for AD. circulation_biomarker_diagnosis_ns hsa-mir-150 Sepsis 24146790 microRNA miR-150 and miR-4772-5p-iso were able to discriminate between patients who have systemic inflammatory response syndrome and patients with sepsis. circulation_biomarker_diagnosis_ns hsa-mir-24 Leukemia 24153013 "Altered expression of miR-24, miR-126 and miR-365 does not affect viability of childhood TCF3-rearranged leukemia cells." circulation_biomarker_diagnosis_ns hsa-mir-365 Leukemia 24153013 "Altered expression of miR-24, miR-126 and miR-365 does not affect viability of childhood TCF3-rearranged leukemia cells." circulation_biomarker_diagnosis_ns hsa-mir-127 Breast Neoplasms 24194846 Plasma microRNA panel for minimally invasive detection of breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-148b Breast Neoplasms 24194846 Plasma microRNA panel for minimally invasive detection of breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-376a Breast Neoplasms 24194846 Plasma microRNA panel for minimally invasive detection of breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-376c Breast Neoplasms 24194846 Plasma microRNA panel for minimally invasive detection of breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-409 Breast Neoplasms 24194846 Plasma microRNA panel for minimally invasive detection of breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-652 Breast Neoplasms 24194846 Plasma microRNA panel for minimally invasive detection of breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-801 Breast Neoplasms 24194846 Plasma microRNA panel for minimally invasive detection of breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-138 "Diabetes Mellitus, Type 2" 24204780 "This study is the first to show a panel of serum miRNAs for obesity, and compare them with miRNAs identified in serum for diabetes and obesity with diabetes. Our results support the use of some miRNAs extracted from serum samples as potential predictive tools for obesity and type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-15b "Diabetes Mellitus, Type 2" 24204780 "This study is the first to show a panel of serum miRNAs for obesity, and compare them with miRNAs identified in serum for diabetes and obesity with diabetes. Our results support the use of some miRNAs extracted from serum samples as potential predictive tools for obesity and type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-376a "Diabetes Mellitus, Type 2" 24204780 "This study is the first to show a panel of serum miRNAs for obesity, and compare them with miRNAs identified in serum for diabetes and obesity with diabetes. Our results support the use of some miRNAs extracted from serum samples as potential predictive tools for obesity and type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-503 "Diabetes Mellitus, Type 2" 24204780 "This study is the first to show a panel of serum miRNAs for obesity, and compare them with miRNAs identified in serum for diabetes and obesity with diabetes. Our results support the use of some miRNAs extracted from serum samples as potential predictive tools for obesity and type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-210 "Carcinoma, Renal Cell, Clear-Cell" 24212760 Serum miR-210 as a potential biomarker of early clear cell renal cell carcinoma. circulation_biomarker_diagnosis_ns hsa-let-7b "Stroke, Ischemic" 24237608 "These data suggest that miR-30a, miR-126 and let-7b might be useful biomarkers for ischemic stroke in humans." circulation_biomarker_diagnosis_ns hsa-mir-126 "Stroke, Ischemic" 24237608 "These data suggest that miR-30a, miR-126 and let-7b might be useful biomarkers for ischemic stroke in humans." circulation_biomarker_diagnosis_ns hsa-mir-30a "Stroke, Ischemic" 24237608 "These data suggest that miR-30a, miR-126 and let-7b might be useful biomarkers for ischemic stroke in humans." circulation_biomarker_diagnosis_ns hsa-mir-34a "Carcinoma, Adrenocortical" 24238045 We show that dysregulated miRNAs in ACC are detectable in human serum samples. MiR-34a and miR-483-5p are candidate serum biomarkers for distinguishing between benign and malignant adrenocortical tumors. circulation_biomarker_diagnosis_ns hsa-mir-483 "Carcinoma, Adrenocortical" 24238045 We show that dysregulated miRNAs in ACC are detectable in human serum samples. MiR-34a and miR-483-5p are candidate serum biomarkers for distinguishing between benign and malignant adrenocortical tumors. circulation_biomarker_diagnosis_ns hsa-mir-1 Acute Myocardial Infarction 24253456 Early in acute myocardial infarction the expression of miR-423-5p in plasma is significantly increased with subsequent normalization within 6 hours.Potentially it is an early marker of myocardial necrosis. circulation_biomarker_diagnosis_ns hsa-mir-195 "Adenocarcinoma, Lung" 24282590 "Plasma levels of miR-195 and miR-122 expression were also associated with overall survival in the patients, especially in those with advanced stage (HR=0.23, 95%CI:0.07-0.84; and HR=0.22, 95%CI:0.06-0.77) and EGFR mutation (HR=0.27, 95%CI:0.08-0.96; and HR=0.23, 95%CI=0.06-0.81)." circulation_biomarker_diagnosis_ns hsa-let-7b Myocardial Infarction 24284400 "The circulating let-7b is suspected to be the biomarker of acute MI and let-7i, the biomarker of DCM." circulation_biomarker_diagnosis_ns hsa-mir-122 Liver Injury 24287929 Plasma miR-122 expression is correlated with hepatectomy-induced liver injury in patients with HCC. Increase in miR-122 expression could be used as an index of such injury before and after hepatectomy in these patients. circulation_biomarker_diagnosis_ns hsa-mir-146b "Carcinoma, Thyroid, Papillary" 24301304 This study demonstrated that tumor levels of miR-222 and miR-146b are associated with PTC recurrence and that miR-222 and miR-146b levels in the circulation correspond to the presence of PTC. The potential of these miRNAs as tumor biomarkers to improve patient stratification according to the risk of recurrence and as circulating biomarkers for PTC surveillance warrants further study. circulation_biomarker_diagnosis_ns hsa-mir-222 "Carcinoma, Thyroid, Papillary" 24301304 This study demonstrated that tumor levels of miR-222 and miR-146b are associated with PTC recurrence and that miR-222 and miR-146b levels in the circulation correspond to the presence of PTC. The potential of these miRNAs as tumor biomarkers to improve patient stratification according to the risk of recurrence and as circulating biomarkers for PTC surveillance warrants further study. circulation_biomarker_diagnosis_ns hsa-mir-122 HELLP Syndrome 24304191 "In our proof of principle study, we demonstrated that patients with HELLP syndrome showed alterations of serum miRNA expression patterns. Data analysis goes along with the hypothesis that HELLP syndrome is regarded to be a heterogeneous disease." circulation_biomarker_diagnosis_ns hsa-mir-133a HELLP Syndrome 24304191 "In our proof of principle study, we demonstrated that patients with HELLP syndrome showed alterations of serum miRNA expression patterns. Data analysis goes along with the hypothesis that HELLP syndrome is regarded to be a heterogeneous disease." circulation_biomarker_diagnosis_ns hsa-mir-758 HELLP Syndrome 24304191 "In our proof of principle study, we demonstrated that patients with HELLP syndrome showed alterations of serum miRNA expression patterns. Data analysis goes along with the hypothesis that HELLP syndrome is regarded to be a heterogeneous disease." circulation_biomarker_diagnosis_ns hsa-mir-122 "Fatty Liver, Non-Alcoholic" 24313922 We found that the hepatic and serum miR-122 levels were associated with hepatic steatosis and fibrosis. The serum miR-122 level can be a useful predictive marker of liver fibrosis in patients with NAFLD. circulation_biomarker_diagnosis_ns hsa-mir-9 "Carcinoma, Nasopharyngeal" 24327016 Our study reports that plasma miR-9 may serve as a useful biomarker to predict NPC metastasis and to monitor tumour dynamics. circulation_biomarker_diagnosis_ns hsa-mir-100 Adrenal Cortex Neoplasms 24336071 "In contrast, of the selected eight miRNAs reported in the literature as differentially expressed in ACT tissues, five (hsa-miR-100, hsa-miR-181b, hsa-miR-184, hsa-miR-210 and hsa-miR-483-5p) showed a statistically significant overexpression in adrenocortical cancer vs adenoma when normalized on hsa-miR-16 as a reference gene." circulation_biomarker_diagnosis_ns hsa-mir-210 Adrenal Cortex Neoplasms 24336071 "In contrast, of the selected eight miRNAs reported in the literature as differentially expressed in ACT tissues, five (hsa-miR-100, hsa-miR-181b, hsa-miR-184, hsa-miR-210 and hsa-miR-483-5p) showed a statistically significant overexpression in adrenocortical cancer vs adenoma when normalized on hsa-miR-16 as a reference gene." circulation_biomarker_diagnosis_ns hsa-mir-128 Mild Cognitive Impairment 24368295 Plasma microRNA biomarkers for detection of mild cognitive impairment: biomarker validation study. circulation_biomarker_diagnosis_ns hsa-mir-132 Mild Cognitive Impairment 24368295 Plasma microRNA biomarkers for detection of mild cognitive impairment: biomarker validation study. circulation_biomarker_diagnosis_ns hsa-mir-134 Mild Cognitive Impairment 24368295 Plasma microRNA biomarkers for detection of mild cognitive impairment: biomarker validation study. circulation_biomarker_diagnosis_ns hsa-mir-323 Mild Cognitive Impairment 24368295 Plasma microRNA biomarkers for detection of mild cognitive impairment: biomarker validation study. circulation_biomarker_diagnosis_ns hsa-mir-370 Mild Cognitive Impairment 24368295 Plasma microRNA biomarkers for detection of mild cognitive impairment: biomarker validation study. circulation_biomarker_diagnosis_ns hsa-mir-382 Mild Cognitive Impairment 24368295 Plasma microRNA biomarkers for detection of mild cognitive impairment: biomarker validation study. circulation_biomarker_diagnosis_ns hsa-mir-491 Mild Cognitive Impairment 24368295 Plasma microRNA biomarkers for detection of mild cognitive impairment: biomarker validation study. circulation_biomarker_diagnosis_ns hsa-mir-874 Mild Cognitive Impairment 24368295 Plasma microRNA biomarkers for detection of mild cognitive impairment: biomarker validation study. circulation_biomarker_diagnosis_ns hsa-mir-125b Uveal Melanoma 24370793 The development of metastasis in uveal melanoma is associated with changes in immune effector and regulatory cells consistent with lessening tumor immune surveillance. These changes are associated with changes in plasma and cellular levels of immune regulatory miRs. The results may help guide uveal melanoma immunotherapy and biomarker development. circulation_biomarker_diagnosis_ns hsa-mir-146a Uveal Melanoma 24370793 The development of metastasis in uveal melanoma is associated with changes in immune effector and regulatory cells consistent with lessening tumor immune surveillance. These changes are associated with changes in plasma and cellular levels of immune regulatory miRs. The results may help guide uveal melanoma immunotherapy and biomarker development. circulation_biomarker_diagnosis_ns hsa-mir-155 Uveal Melanoma 24370793 The development of metastasis in uveal melanoma is associated with changes in immune effector and regulatory cells consistent with lessening tumor immune surveillance. These changes are associated with changes in plasma and cellular levels of immune regulatory miRs. The results may help guide uveal melanoma immunotherapy and biomarker development. circulation_biomarker_diagnosis_ns hsa-mir-20a Uveal Melanoma 24370793 The development of metastasis in uveal melanoma is associated with changes in immune effector and regulatory cells consistent with lessening tumor immune surveillance. These changes are associated with changes in plasma and cellular levels of immune regulatory miRs. The results may help guide uveal melanoma immunotherapy and biomarker development. circulation_biomarker_diagnosis_ns hsa-mir-223 Uveal Melanoma 24370793 The development of metastasis in uveal melanoma is associated with changes in immune effector and regulatory cells consistent with lessening tumor immune surveillance. These changes are associated with changes in plasma and cellular levels of immune regulatory miRs. The results may help guide uveal melanoma immunotherapy and biomarker development. circulation_biomarker_diagnosis_ns hsa-mir-21 "Lymphoma, Large B-Cell, Diffuse" 24400911 Clinical significance and detection of microRNA-21 in serum of patients with diffuse large B-cell lymphoma in Chinese population. circulation_biomarker_diagnosis_ns hsa-mir-133a Sepsis 24413579 Levels of circulating miR-133a are elevated in sepsis and predict mortality in critically ill patients. circulation_biomarker_diagnosis_ns hsa-mir-223 Immune Thrombocytopenic Purpura 24418947 Plasma microRNA profiling of pediatric patients with immune thrombocytopenic purpura. circulation_biomarker_diagnosis_ns hsa-mir-302a Immune Thrombocytopenic Purpura 24418947 Plasma microRNA profiling of pediatric patients with immune thrombocytopenic purpura. circulation_biomarker_diagnosis_ns hsa-mir-302c Immune Thrombocytopenic Purpura 24418947 Plasma microRNA profiling of pediatric patients with immune thrombocytopenic purpura. circulation_biomarker_diagnosis_ns hsa-mir-410 Immune Thrombocytopenic Purpura 24418947 Plasma microRNA profiling of pediatric patients with immune thrombocytopenic purpura. circulation_biomarker_diagnosis_ns hsa-mir-483 Immune Thrombocytopenic Purpura 24418947 Plasma microRNA profiling of pediatric patients with immune thrombocytopenic purpura. circulation_biomarker_diagnosis_ns hsa-mir-544a Immune Thrombocytopenic Purpura 24418947 Plasma microRNA profiling of pediatric patients with immune thrombocytopenic purpura. circulation_biomarker_diagnosis_ns hsa-mir-597 Immune Thrombocytopenic Purpura 24418947 Plasma microRNA profiling of pediatric patients with immune thrombocytopenic purpura. circulation_biomarker_diagnosis_ns hsa-mir-122 Sepsis 24421215 Serum miR-122 levels are related to coagulation disorders in sepsis patients. circulation_biomarker_diagnosis_ns hsa-mir-378 Colorectal Carcinoma 24423916 "Plasma levels of miR-378 could be used to discriminate CRC patients from healthy individuals, irrespective of the level of haemoglobin of plasma samples." circulation_biomarker_diagnosis_ns hsa-mir-122 Pancreatic Neoplasms 24449318 MicroRNA biomarkers in whole blood for detection of pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-126 Pancreatic Neoplasms 24449318 MicroRNA biomarkers in whole blood for detection of pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-145 Pancreatic Neoplasms 24449318 MicroRNA biomarkers in whole blood for detection of pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-150 Pancreatic Neoplasms 24449318 MicroRNA biomarkers in whole blood for detection of pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-223 Pancreatic Neoplasms 24449318 MicroRNA biomarkers in whole blood for detection of pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-26b Pancreatic Neoplasms 24449318 MicroRNA biomarkers in whole blood for detection of pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-34a Pancreatic Neoplasms 24449318 MicroRNA biomarkers in whole blood for detection of pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-505 Pancreatic Neoplasms 24449318 MicroRNA biomarkers in whole blood for detection of pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-636 Pancreatic Neoplasms 24449318 MicroRNA biomarkers in whole blood for detection of pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-885 Pancreatic Neoplasms 24449318 MicroRNA biomarkers in whole blood for detection of pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-186 "Squamous Cell Carcinoma, Oral" 24452363 "miR-186, miR-3651 and miR-494: potential biomarkers for oral squamous cell carcinoma extracted from whole blood." circulation_biomarker_diagnosis_ns hsa-mir-3651 "Squamous Cell Carcinoma, Oral" 24452363 "miR-186, miR-3651 and miR-494: potential biomarkers for oral squamous cell carcinoma extracted from whole blood." circulation_biomarker_diagnosis_ns hsa-mir-494 "Squamous Cell Carcinoma, Oral" 24452363 "miR-186, miR-3651 and miR-494: potential biomarkers for oral squamous cell carcinoma extracted from whole blood." circulation_biomarker_diagnosis_ns hsa-mir-126 "Diabetes Mellitus, Type 2" 24455723 Plasma miR-126 is a potential biomarker for early prediction of type 2 diabetes mellitus in susceptible individuals. circulation_biomarker_diagnosis_ns hsa-mir-1827 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-1973 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-298 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-299 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-3201 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-3611 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-3646 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-3686 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-3915 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-423 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-4268 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-4279 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-4290 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-483 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-498 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-518b "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-525 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-612 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-665 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-711 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-943 "Leukemia, Myeloid, Chronic" 24460325 Selective miRNA expression profile in chronic myeloid leukemia K562 cell-derived exosomes. circulation_biomarker_diagnosis_ns hsa-mir-1 "Muscular Dystrophy, Duchenne" 24460924 Serum miR-206 and other muscle-specific microRNAs as non-invasive biomarkers for Duchenne muscular dystrophy. circulation_biomarker_diagnosis_ns hsa-mir-133 "Muscular Dystrophy, Duchenne" 24460924 Serum miR-206 and other muscle-specific microRNAs as non-invasive biomarkers for Duchenne muscular dystrophy. circulation_biomarker_diagnosis_ns hsa-mir-206 "Muscular Dystrophy, Duchenne" 24460924 Serum miR-206 and other muscle-specific microRNAs as non-invasive biomarkers for Duchenne muscular dystrophy. circulation_biomarker_diagnosis_ns hsa-mir-628 Prostate Neoplasms 24477576 "Our results demonstrate that the three miRNAs, particularly miR-628-5p, may be further developed as a biomarker, which can serve as novel noninvasive biomarker for PCa diagnosis and prognosis." circulation_biomarker_diagnosis_ns hsa-mir-126 "Leukemia, Myeloid, Acute" 24477595 Attenuation of microRNA-126 expression that drives CD34+38- stem/progenitor cells in acute myeloid leukemia leads to tumor eradication. circulation_biomarker_diagnosis_ns hsa-mir-122 Gastric Neoplasms 24481716 Plasma miR-122 and miR-192 as potential novel biomarkers for the early detection of distant metastasis of gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-192 Gastric Neoplasms 24481716 Plasma miR-122 and miR-192 as potential novel biomarkers for the early detection of distant metastasis of gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-182 Breast Neoplasms 24498016 "This study provides insight into the underlying molecular portrait of Luminal A-like breast cancer subtype. From an initial 76 miRNAs, 4 were validated with altered expression in the blood of women with Luminal A-like breast cancer. The expression profiles of these 3 miRNAs, in combination with mammography, has potential to facilitate accurate subtype-specific breast tumor detection." circulation_biomarker_diagnosis_ns hsa-mir-19b Breast Neoplasms 24498016 "This study provides insight into the underlying molecular portrait of Luminal A-like breast cancer subtype. From an initial 76 miRNAs, 4 were validated with altered expression in the blood of women with Luminal A-like breast cancer. The expression profiles of these 3 miRNAs, in combination with mammography, has potential to facilitate accurate subtype-specific breast tumor detection." circulation_biomarker_diagnosis_ns hsa-mir-223 Breast Neoplasms 24498016 "This study provides insight into the underlying molecular portrait of Luminal A-like breast cancer subtype. From an initial 76 miRNAs, 4 were validated with altered expression in the blood of women with Luminal A-like breast cancer. The expression profiles of these 3 miRNAs, in combination with mammography, has potential to facilitate accurate subtype-specific breast tumor detection." circulation_biomarker_diagnosis_ns hsa-mir-29a Breast Neoplasms 24498016 "This study provides insight into the underlying molecular portrait of Luminal A-like breast cancer subtype. From an initial 76 miRNAs, 4 were validated with altered expression in the blood of women with Luminal A-like breast cancer. The expression profiles of these 3 miRNAs, in combination with mammography, has potential to facilitate accurate subtype-specific breast tumor detection." circulation_biomarker_diagnosis_ns hsa-mir-301a Breast Neoplasms 24498016 "This study provides insight into the underlying molecular portrait of Luminal A-like breast cancer subtype. From an initial 76 miRNAs, 4 were validated with altered expression in the blood of women with Luminal A-like breast cancer. The expression profiles of these 3 miRNAs, in combination with mammography, has potential to facilitate accurate subtype-specific breast tumor detection." circulation_biomarker_diagnosis_ns hsa-mir-423 Breast Neoplasms 24498016 "This study provides insight into the underlying molecular portrait of Luminal A-like breast cancer subtype. From an initial 76 miRNAs, 4 were validated with altered expression in the blood of women with Luminal A-like breast cancer. The expression profiles of these 3 miRNAs, in combination with mammography, has potential to facilitate accurate subtype-specific breast tumor detection." circulation_biomarker_diagnosis_ns hsa-mir-486 Breast Neoplasms 24498016 "This study provides insight into the underlying molecular portrait of Luminal A-like breast cancer subtype. From an initial 76 miRNAs, 4 were validated with altered expression in the blood of women with Luminal A-like breast cancer. The expression profiles of these 3 miRNAs, in combination with mammography, has potential to facilitate accurate subtype-specific breast tumor detection." circulation_biomarker_diagnosis_ns hsa-mir-652 Breast Neoplasms 24498016 "This study provides insight into the underlying molecular portrait of Luminal A-like breast cancer subtype. From an initial 76 miRNAs, 4 were validated with altered expression in the blood of women with Luminal A-like breast cancer. The expression profiles of these 3 miRNAs, in combination with mammography, has potential to facilitate accurate subtype-specific breast tumor detection." circulation_biomarker_diagnosis_ns hsa-mir-93 Breast Neoplasms 24498016 "This study provides insight into the underlying molecular portrait of Luminal A-like breast cancer subtype. From an initial 76 miRNAs, 4 were validated with altered expression in the blood of women with Luminal A-like breast cancer. The expression profiles of these 3 miRNAs, in combination with mammography, has potential to facilitate accurate subtype-specific breast tumor detection." circulation_biomarker_diagnosis_ns hsa-mir-21 Myelodysplastic Syndromes 24503739 Serum microRNA-21 as a potential biomarker for response to hypomethylating agents in myelodysplastic syndromes. circulation_biomarker_diagnosis_ns hsa-mir-29c Early-Stage Non-Small-Cell Lung Carcinoma 24523873 "The results of the current study suggest that detection of serum miR-29c and miR-429 expression should be further evaluated as a novel,non-invasive biomarker for early stage NSCLC." circulation_biomarker_diagnosis_ns hsa-mir-429 Early-Stage Non-Small-Cell Lung Carcinoma 24523873 "The results of the current study suggest that detection of serum miR-29c and miR-429 expression should be further evaluated as a novel,non-invasive biomarker for early stage NSCLC." circulation_biomarker_diagnosis_ns hsa-mir-93 Early-Stage Non-Small-Cell Lung Carcinoma 24523873 "The results of the current study suggest that detection of serum miR-29c and miR-429 expression should be further evaluated as a novel,non-invasive biomarker for early stage NSCLC." circulation_biomarker_diagnosis_ns hsa-mir-499 Myocardial Infarction 24533109 "MiRNAs, especially miR-499 and miR-133a, may be suitable for use as diagnostic biomarkers of myocardial infarction." circulation_biomarker_diagnosis_ns hsa-mir-499 "Carcinoma, Lung, Non-Small-Cell" 24549225 Serum miR-499 as a novel diagnostic and prognostic biomarker in non-small cell lung cancer. circulation_biomarker_diagnosis_ns hsa-mir-206 Early-Stage Lung Carcinoma 24553369 4-(Methylnitrosamino)-1-(3-pyridyl) -1-butanone induces circulating microRNA deregulation in early lung carcinogenesis. circulation_biomarker_diagnosis_ns hsa-mir-210 Early-Stage Lung Carcinoma 24553369 4-(Methylnitrosamino)-1-(3-pyridyl) -1-butanone induces circulating microRNA deregulation in early lung carcinogenesis. circulation_biomarker_diagnosis_ns hsa-mir-223 Cardiovascular Diseases [unspecific] 24573468 Smoking alters circulating plasma microvesicle pattern and microRNA signatures. circulation_biomarker_diagnosis_ns hsa-mir-29b Cardiovascular Diseases [unspecific] 24573468 Smoking alters circulating plasma microvesicle pattern and microRNA signatures. circulation_biomarker_diagnosis_ns hsa-mir-34a Colorectal Carcinoma 24573638 Detection of miR-34a and miR-34b/c in stool sample as potential screening biomarkers for noninvasive diagnosis of colorectal cancer. circulation_biomarker_diagnosis_ns hsa-mir-34b Colorectal Carcinoma 24573638 Detection of miR-34a and miR-34b/c in stool sample as potential screening biomarkers for noninvasive diagnosis of colorectal cancer. circulation_biomarker_diagnosis_ns hsa-mir-34c Colorectal Carcinoma 24573638 Detection of miR-34a and miR-34b/c in stool sample as potential screening biomarkers for noninvasive diagnosis of colorectal cancer. circulation_biomarker_diagnosis_ns hsa-let-7d Alzheimer Disease 24577456 Genome-wide serum microRNA expression profiling identifies serum biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-191 Alzheimer Disease 24577456 Genome-wide serum microRNA expression profiling identifies serum biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-342 Alzheimer Disease 24577456 Genome-wide serum microRNA expression profiling identifies serum biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-483 Alzheimer Disease 24577456 Genome-wide serum microRNA expression profiling identifies serum biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-885 Alzheimer Disease 24577456 Genome-wide serum microRNA expression profiling identifies serum biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-98 Alzheimer Disease 24577456 Genome-wide serum microRNA expression profiling identifies serum biomarkers for Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-let-7a Breast Neoplasms 24584717 "In summary, the data suggested that miRNAs in milk from milk stasis patients may contribute to breast carcinogenesis and that they are more sensitive biomarkers for breast cancer than miRNAs in the blood." circulation_biomarker_diagnosis_ns hsa-mir-10 Breast Neoplasms 24584717 "In summary, the data suggested that miRNAs in milk from milk stasis patients may contribute to breast carcinogenesis and that they are more sensitive biomarkers for breast cancer than miRNAs in the blood." circulation_biomarker_diagnosis_ns hsa-mir-107 Breast Neoplasms 24584717 "In summary, the data suggested that miRNAs in milk from milk stasis patients may contribute to breast carcinogenesis and that they are more sensitive biomarkers for breast cancer than miRNAs in the blood." circulation_biomarker_diagnosis_ns hsa-mir-140 Breast Neoplasms 24584717 "In summary, the data suggested that miRNAs in milk from milk stasis patients may contribute to breast carcinogenesis and that they are more sensitive biomarkers for breast cancer than miRNAs in the blood." circulation_biomarker_diagnosis_ns hsa-mir-146 Breast Neoplasms 24584717 "In summary, the data suggested that miRNAs in milk from milk stasis patients may contribute to breast carcinogenesis and that they are more sensitive biomarkers for breast cancer than miRNAs in the blood." circulation_biomarker_diagnosis_ns hsa-mir-21 Breast Neoplasms 24584717 "In summary, the data suggested that miRNAs in milk from milk stasis patients may contribute to breast carcinogenesis and that they are more sensitive biomarkers for breast cancer than miRNAs in the blood." circulation_biomarker_diagnosis_ns hsa-mir-223 Breast Neoplasms 24584717 "In summary, the data suggested that miRNAs in milk from milk stasis patients may contribute to breast carcinogenesis and that they are more sensitive biomarkers for breast cancer than miRNAs in the blood." circulation_biomarker_diagnosis_ns hsa-mir-29a Breast Neoplasms 24584717 "In summary, the data suggested that miRNAs in milk from milk stasis patients may contribute to breast carcinogenesis and that they are more sensitive biomarkers for breast cancer than miRNAs in the blood." circulation_biomarker_diagnosis_ns hsa-mir-451 Breast Neoplasms 24584717 "In summary, the data suggested that miRNAs in milk from milk stasis patients may contribute to breast carcinogenesis and that they are more sensitive biomarkers for breast cancer than miRNAs in the blood." circulation_biomarker_diagnosis_ns hsa-mir-486 Breast Neoplasms 24584717 "In summary, the data suggested that miRNAs in milk from milk stasis patients may contribute to breast carcinogenesis and that they are more sensitive biomarkers for breast cancer than miRNAs in the blood." circulation_biomarker_diagnosis_ns hsa-mir-92 Breast Neoplasms 24584717 "In summary, the data suggested that miRNAs in milk from milk stasis patients may contribute to breast carcinogenesis and that they are more sensitive biomarkers for breast cancer than miRNAs in the blood." circulation_biomarker_diagnosis_ns hsa-mir-21 Colorectal Carcinoma 24586105 Re: Serum miR-21 as a diagnostic and prognostic biomarker in colorectal cancer. circulation_biomarker_diagnosis_ns hsa-mir-206 Amyotrophic Lateral Sclerosis 24586506 MicroRNA-206: a potential circulating biomarker candidate for amyotrophic lateral sclerosis. circulation_biomarker_diagnosis_ns hsa-mir-122 Non-Neoplastic Diseases 24586876 "Only a subset of reported blood-based microRNA biomarkers have specificity for a particular disease. The remainder of the reported non-neoplastic biomarkers are either biologically implausible, non-specific, or uninterpretable due to limitations of our current understanding of microRNA expression." circulation_biomarker_diagnosis_ns hsa-mir-126 Non-Neoplastic Diseases 24586876 "Only a subset of reported blood-based microRNA biomarkers have specificity for a particular disease. The remainder of the reported non-neoplastic biomarkers are either biologically implausible, non-specific, or uninterpretable due to limitations of our current understanding of microRNA expression." circulation_biomarker_diagnosis_ns hsa-mir-146a Non-Neoplastic Diseases 24586876 "Only a subset of reported blood-based microRNA biomarkers have specificity for a particular disease. The remainder of the reported non-neoplastic biomarkers are either biologically implausible, non-specific, or uninterpretable due to limitations of our current understanding of microRNA expression." circulation_biomarker_diagnosis_ns hsa-mir-155 Non-Neoplastic Diseases 24586876 "Only a subset of reported blood-based microRNA biomarkers have specificity for a particular disease. The remainder of the reported non-neoplastic biomarkers are either biologically implausible, non-specific, or uninterpretable due to limitations of our current understanding of microRNA expression." circulation_biomarker_diagnosis_ns hsa-mir-16 Non-Neoplastic Diseases 24586876 "Only a subset of reported blood-based microRNA biomarkers have specificity for a particular disease. The remainder of the reported non-neoplastic biomarkers are either biologically implausible, non-specific, or uninterpretable due to limitations of our current understanding of microRNA expression." circulation_biomarker_diagnosis_ns hsa-mir-21 Non-Neoplastic Diseases 24586876 "Only a subset of reported blood-based microRNA biomarkers have specificity for a particular disease. The remainder of the reported non-neoplastic biomarkers are either biologically implausible, non-specific, or uninterpretable due to limitations of our current understanding of microRNA expression." circulation_biomarker_diagnosis_ns hsa-mir-223 Non-Neoplastic Diseases 24586876 "Only a subset of reported blood-based microRNA biomarkers have specificity for a particular disease. The remainder of the reported non-neoplastic biomarkers are either biologically implausible, non-specific, or uninterpretable due to limitations of our current understanding of microRNA expression." circulation_biomarker_diagnosis_ns hsa-mir-16 Early-Stage Gastric Carcinoma 24595006 A five-microRNA panel in plasma was identified as potential biomarker for early detection of gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-25 Early-Stage Gastric Carcinoma 24595006 A five-microRNA panel in plasma was identified as potential biomarker for early detection of gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-451 Early-Stage Gastric Carcinoma 24595006 A five-microRNA panel in plasma was identified as potential biomarker for early detection of gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-486 Early-Stage Gastric Carcinoma 24595006 A five-microRNA panel in plasma was identified as potential biomarker for early detection of gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-92a Early-Stage Gastric Carcinoma 24595006 A five-microRNA panel in plasma was identified as potential biomarker for early detection of gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-125b Hepatitis B Virus Infection 24595450 Profiles of serum microRNAs; miR-125b-5p and miR223-3p serve as novel biomarkers for HBV-positive hepatocellular carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-223 Hepatitis B Virus Infection 24595450 Profiles of serum microRNAs; miR-125b-5p and miR223-3p serve as novel biomarkers for HBV-positive hepatocellular carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-16 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 24598659 Expression of miR-16 in patients with T lymphoblastic lymphoma/acute lymphoblastic leukemia. circulation_biomarker_diagnosis_ns hsa-mir-425 Gastric Neoplasms 24603541 "Taken together, our results revealed the oncogenic roles of miR-191 and miR-425 in gastric carcinogenesis, and indicated the potential use of serum miR-191 as a novel and stable biomarker for GC diagnosis." circulation_biomarker_diagnosis_ns hsa-mir-18a Gastric Neoplasms 24626859 Circulating miR-18a could be a useful biomarker for screening GC and monitoring tumor dynamics. circulation_biomarker_diagnosis_ns hsa-mir-122 Myasthenia Gravis 24637658 Analysis of serum miRNA profiles of myasthenia gravis patients. circulation_biomarker_diagnosis_ns hsa-mir-140 Myasthenia Gravis 24637658 Analysis of serum miRNA profiles of myasthenia gravis patients. circulation_biomarker_diagnosis_ns hsa-mir-15b Myasthenia Gravis 24637658 Analysis of serum miRNA profiles of myasthenia gravis patients. circulation_biomarker_diagnosis_ns hsa-mir-185 Myasthenia Gravis 24637658 Analysis of serum miRNA profiles of myasthenia gravis patients. circulation_biomarker_diagnosis_ns hsa-mir-192 Myasthenia Gravis 24637658 Analysis of serum miRNA profiles of myasthenia gravis patients. circulation_biomarker_diagnosis_ns hsa-mir-20b Myasthenia Gravis 24637658 Analysis of serum miRNA profiles of myasthenia gravis patients. circulation_biomarker_diagnosis_ns hsa-mir-885 Myasthenia Gravis 24637658 Analysis of serum miRNA profiles of myasthenia gravis patients. circulation_biomarker_diagnosis_ns hsa-mir-106b Ovarian Neoplasms 24641401 "This study shows that Solexa sequencing provides a promising method for cancer-related miRNA profiling, and selectively expressed miRNAs could be used as potential serum-based biomarkers for ovarian cancer diagnosis." circulation_biomarker_diagnosis_ns hsa-mir-22 Ovarian Neoplasms 24641401 "This study shows that Solexa sequencing provides a promising method for cancer-related miRNA profiling, and selectively expressed miRNAs could be used as potential serum-based biomarkers for ovarian cancer diagnosis." circulation_biomarker_diagnosis_ns hsa-mir-451 Ovarian Neoplasms 24641401 "This study shows that Solexa sequencing provides a promising method for cancer-related miRNA profiling, and selectively expressed miRNAs could be used as potential serum-based biomarkers for ovarian cancer diagnosis." circulation_biomarker_diagnosis_ns hsa-mir-93 Ovarian Neoplasms 24641401 "This study shows that Solexa sequencing provides a promising method for cancer-related miRNA profiling, and selectively expressed miRNAs could be used as potential serum-based biomarkers for ovarian cancer diagnosis." circulation_biomarker_diagnosis_ns hsa-mir-484 Early-Stage Breast Carcinoma 24641801 "In this study, we found that miR-484 is significantly differentially expressed in serum of early breast cancer patients compared to healthy volunteers. We did not however find any correlation between miR-484 levels with histopathological parameters of the breast cancers. With further studies, miR-484 may prove useful as an adjunct to mammography for detection of early breast cancer." circulation_biomarker_diagnosis_ns hsa-mir-122 Chronic Hepatitis B 24643113 "Comparison of circulating, hepatocyte specific messenger RNA and microRNA as biomarkers for chronic hepatitis B and C." circulation_biomarker_diagnosis_ns hsa-mir-122 Chronic Hepatitis C 24643113 "Comparison of circulating, hepatocyte specific messenger RNA and microRNA as biomarkers for chronic hepatitis B and C." circulation_biomarker_diagnosis_ns hsa-mir-15b Colorectal Carcinoma 24646542 miR-15b and miR-17 Are Tumor-derived Plasma MicroRNAs Dysregulated in Colorectal Neoplasia. circulation_biomarker_diagnosis_ns hsa-mir-17 Colorectal Carcinoma 24646542 miR-15b and miR-17 Are Tumor-derived Plasma MicroRNAs Dysregulated in Colorectal Neoplasia. circulation_biomarker_diagnosis_ns hsa-mir-33 Psoriasis 24656994 In psoriasis patients plasma levels of lipid and glucose metabolism-related miRNA-33 are increased and correlated with insulin. The study of circulating miRNA-33 in psoriasis may provide new insights about the associated systemic inflammatory abnormalities. circulation_biomarker_diagnosis_ns hsa-mir-223 "Lymphoma, Non-Hodgkin" 24675587 "Altered serum levels of miR-21, miR-122, and miR-223 are seen in HIV-infected individuals." circulation_biomarker_diagnosis_ns hsa-mir-135b Colorectal Carcinoma 24691020 Stool-based miR-135b can be used as a noninvasive biomarker for the detection of CRC and advanced adenoma. circulation_biomarker_diagnosis_ns hsa-mir-107 Early-Stage Breast Carcinoma 24694649 "We present herein a 9 miRNA signature capable of discriminating between ER-positive breast cancer and healthy controls. Using a specific algorithm based on the 9 miRNA signature, the risk for future individuals can be predicted. Since microRNAs are highly stable in blood components, this signature might be useful in the development of a blood-based multi-marker test to improve early detection of breast cancer. Such a test could potentially be used as a screening tool to identify individuals who would benefit from further diagnostic assessment." circulation_biomarker_diagnosis_ns hsa-mir-133a Early-Stage Breast Carcinoma 24694649 "We present herein a 9 miRNA signature capable of discriminating between ER-positive breast cancer and healthy controls. Using a specific algorithm based on the 9 miRNA signature, the risk for future individuals can be predicted. Since microRNAs are highly stable in blood components, this signature might be useful in the development of a blood-based multi-marker test to improve early detection of breast cancer. Such a test could potentially be used as a screening tool to identify individuals who would benefit from further diagnostic assessment." circulation_biomarker_diagnosis_ns hsa-mir-139 Early-Stage Breast Carcinoma 24694649 "We present herein a 9 miRNA signature capable of discriminating between ER-positive breast cancer and healthy controls. Using a specific algorithm based on the 9 miRNA signature, the risk for future individuals can be predicted. Since microRNAs are highly stable in blood components, this signature might be useful in the development of a blood-based multi-marker test to improve early detection of breast cancer. Such a test could potentially be used as a screening tool to identify individuals who would benefit from further diagnostic assessment." circulation_biomarker_diagnosis_ns hsa-mir-143 Early-Stage Breast Carcinoma 24694649 "We present herein a 9 miRNA signature capable of discriminating between ER-positive breast cancer and healthy controls. Using a specific algorithm based on the 9 miRNA signature, the risk for future individuals can be predicted. Since microRNAs are highly stable in blood components, this signature might be useful in the development of a blood-based multi-marker test to improve early detection of breast cancer. Such a test could potentially be used as a screening tool to identify individuals who would benefit from further diagnostic assessment." circulation_biomarker_diagnosis_ns hsa-mir-145 Early-Stage Breast Carcinoma 24694649 "We present herein a 9 miRNA signature capable of discriminating between ER-positive breast cancer and healthy controls. Using a specific algorithm based on the 9 miRNA signature, the risk for future individuals can be predicted. Since microRNAs are highly stable in blood components, this signature might be useful in the development of a blood-based multi-marker test to improve early detection of breast cancer. Such a test could potentially be used as a screening tool to identify individuals who would benefit from further diagnostic assessment." circulation_biomarker_diagnosis_ns hsa-mir-15a Early-Stage Breast Carcinoma 24694649 "We present herein a 9 miRNA signature capable of discriminating between ER-positive breast cancer and healthy controls. Using a specific algorithm based on the 9 miRNA signature, the risk for future individuals can be predicted. Since microRNAs are highly stable in blood components, this signature might be useful in the development of a blood-based multi-marker test to improve early detection of breast cancer. Such a test could potentially be used as a screening tool to identify individuals who would benefit from further diagnostic assessment." circulation_biomarker_diagnosis_ns hsa-mir-18a Early-Stage Breast Carcinoma 24694649 "We present herein a 9 miRNA signature capable of discriminating between ER-positive breast cancer and healthy controls. Using a specific algorithm based on the 9 miRNA signature, the risk for future individuals can be predicted. Since microRNAs are highly stable in blood components, this signature might be useful in the development of a blood-based multi-marker test to improve early detection of breast cancer. Such a test could potentially be used as a screening tool to identify individuals who would benefit from further diagnostic assessment." circulation_biomarker_diagnosis_ns hsa-mir-365 Early-Stage Breast Carcinoma 24694649 "We present herein a 9 miRNA signature capable of discriminating between ER-positive breast cancer and healthy controls. Using a specific algorithm based on the 9 miRNA signature, the risk for future individuals can be predicted. Since microRNAs are highly stable in blood components, this signature might be useful in the development of a blood-based multi-marker test to improve early detection of breast cancer. Such a test could potentially be used as a screening tool to identify individuals who would benefit from further diagnostic assessment." circulation_biomarker_diagnosis_ns hsa-mir-425 Early-Stage Breast Carcinoma 24694649 "We present herein a 9 miRNA signature capable of discriminating between ER-positive breast cancer and healthy controls. Using a specific algorithm based on the 9 miRNA signature, the risk for future individuals can be predicted. Since microRNAs are highly stable in blood components, this signature might be useful in the development of a blood-based multi-marker test to improve early detection of breast cancer. Such a test could potentially be used as a screening tool to identify individuals who would benefit from further diagnostic assessment." circulation_biomarker_diagnosis_ns hsa-let-7f "Carcinoma, Hepatocellular" 24697119 "Serum miR-16, let-7f, and miR-21 are related with the biological behavior of HCC, which means that they could be considered as the potential indicators to estimate the tumor size or the recurrence of HCC." circulation_biomarker_diagnosis_ns hsa-mir-16 "Carcinoma, Hepatocellular" 24697119 "Serum miR-16, let-7f, and miR-21 are related with the biological behavior of HCC, which means that they could be considered as the potential indicators to estimate the tumor size or the recurrence of HCC." circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Hepatocellular" 24697119 "Serum miR-16, let-7f, and miR-21 are related with the biological behavior of HCC, which means that they could be considered as the potential indicators to estimate the tumor size or the recurrence of HCC." circulation_biomarker_diagnosis_ns hsa-mir-17 Influenza 24699363 Comprehensive characterization of serum microRNA profile in response to the emerging avian influenza A (H7N9) virus infection in humans. circulation_biomarker_diagnosis_ns hsa-mir-20a Influenza 24699363 Comprehensive characterization of serum microRNA profile in response to the emerging avian influenza A (H7N9) virus infection in humans. circulation_biomarker_diagnosis_ns hsa-mir-376c Influenza 24699363 Comprehensive characterization of serum microRNA profile in response to the emerging avian influenza A (H7N9) virus infection in humans. circulation_biomarker_diagnosis_ns hsa-let-7g Colorectal Carcinoma 24709885 Identification of a circulating microRNA signature for colorectal cancer detection. circulation_biomarker_diagnosis_ns hsa-mir-181b Colorectal Carcinoma 24709885 Identification of a circulating microRNA signature for colorectal cancer detection. circulation_biomarker_diagnosis_ns hsa-mir-203 Colorectal Carcinoma 24709885 Identification of a circulating microRNA signature for colorectal cancer detection. circulation_biomarker_diagnosis_ns hsa-mir-21 Colorectal Carcinoma 24709885 Identification of a circulating microRNA signature for colorectal cancer detection. circulation_biomarker_diagnosis_ns hsa-mir-31 Colorectal Carcinoma 24709885 Identification of a circulating microRNA signature for colorectal cancer detection. circulation_biomarker_diagnosis_ns hsa-mir-92a Colorectal Carcinoma 24709885 Identification of a circulating microRNA signature for colorectal cancer detection. circulation_biomarker_diagnosis_ns hsa-mir-186 Myocardial Infarction 24727883 "In a validation phase, a miRNA panel including miR-132, miR-150, and miR-186 showed the highest discriminatory power" circulation_biomarker_diagnosis_ns hsa-mir-105 Breast Neoplasms 24735924 "miR-105 can be detected in the circulation at the premetastatic stage, and its levels in the blood and tumor are associated with ZO-1 expression and metastatic progression in early-stage breast cancer." circulation_biomarker_diagnosis_ns hsa-mir-150 Irritable Bowel Syndrome 24768587 "This preliminary study reports the association of two miRNAs,detected in whole blood, with IBS. These miRNAs link to pain and inflammatory pathways both of which are thought to be dysregulated in IBS. Larger sample sizes are needed to confirm their importance and potential as biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-342 Irritable Bowel Syndrome 24768587 "This preliminary study reports the association of two miRNAs,detected in whole blood, with IBS. These miRNAs link to pain and inflammatory pathways both of which are thought to be dysregulated in IBS. Larger sample sizes are needed to confirm their importance and potential as biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-1207 Metabolic Syndrome 24784704 Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study. circulation_biomarker_diagnosis_ns hsa-mir-1237 Metabolic Syndrome 24784704 Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study. circulation_biomarker_diagnosis_ns hsa-mir-1288 Metabolic Syndrome 24784704 Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study. circulation_biomarker_diagnosis_ns hsa-mir-129-1 Metabolic Syndrome 24784704 Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study. circulation_biomarker_diagnosis_ns hsa-mir-129-2 Metabolic Syndrome 24784704 Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study. circulation_biomarker_diagnosis_ns hsa-mir-144 Metabolic Syndrome 24784704 Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study. circulation_biomarker_diagnosis_ns hsa-mir-331 Metabolic Syndrome 24784704 Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study. circulation_biomarker_diagnosis_ns hsa-mir-484 Metabolic Syndrome 24784704 Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study. circulation_biomarker_diagnosis_ns hsa-mir-625 Metabolic Syndrome 24784704 Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study. circulation_biomarker_diagnosis_ns hsa-mir-18a Neoplasms [unspecific] 24815829 Circulating miR-18a: a sensitive cancer screening biomarker in human cancer. circulation_biomarker_diagnosis_ns hsa-mir-21 Acute Cerebral Infarction 24841240 Identification of miRNA-21 and miRNA-24 in plasma as potential early stage markers of acute cerebral infarction. circulation_biomarker_diagnosis_ns hsa-mir-24 Acute Cerebral Infarction 24841240 Identification of miRNA-21 and miRNA-24 in plasma as potential early stage markers of acute cerebral infarction. circulation_biomarker_diagnosis_ns hsa-mir-3620 Immune Thrombocytopenic Purpura 24851893 The plasma differential miRNA profiles are identified in ITP patients. And miRNA is involved in calcium signaling pathway and T cell receptor signaling pathway may be associated with ITP pathogenesis. circulation_biomarker_diagnosis_ns hsa-mir-378i Immune Thrombocytopenic Purpura 24851893 The plasma differential miRNA profiles are identified in ITP patients. And miRNA is involved in calcium signaling pathway and T cell receptor signaling pathway may be associated with ITP pathogenesis. circulation_biomarker_diagnosis_ns hsa-mir-4721 Immune Thrombocytopenic Purpura 24851893 The plasma differential miRNA profiles are identified in ITP patients. And miRNA is involved in calcium signaling pathway and T cell receptor signaling pathway may be associated with ITP pathogenesis. circulation_biomarker_diagnosis_ns hsa-let-7g Glioma 24858071 miRNA profile of the peripheral blood may serve as a new biomarker for glioma diagnosis with high specificity and sensitivity. circulation_biomarker_diagnosis_ns hsa-mir-320 Glioma 24858071 miRNA profile of the peripheral blood may serve as a new biomarker for glioma diagnosis with high specificity and sensitivity. circulation_biomarker_diagnosis_ns hsa-mir-340 Glioma 24858071 miRNA profile of the peripheral blood may serve as a new biomarker for glioma diagnosis with high specificity and sensitivity. circulation_biomarker_diagnosis_ns hsa-mir-576 Glioma 24858071 miRNA profile of the peripheral blood may serve as a new biomarker for glioma diagnosis with high specificity and sensitivity. circulation_biomarker_diagnosis_ns hsa-mir-626 Glioma 24858071 miRNA profile of the peripheral blood may serve as a new biomarker for glioma diagnosis with high specificity and sensitivity. circulation_biomarker_diagnosis_ns hsa-mir-7 Glioma 24858071 miRNA profile of the peripheral blood may serve as a new biomarker for glioma diagnosis with high specificity and sensitivity. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Lung" 24865991 The current evidence suggests that serum miR-21 can be rapidly measured in lung carcinoma patients and has potential diagnostic value with moderate sensitivity and specificity. Further prospective studies to assess the early stage diagnostic value are needed in the future. circulation_biomarker_diagnosis_ns hsa-mir-126 Cardiovascular Diseases [unspecific] 24874084 We have demonstrated that this panel of five serum miRNAs is expected to become potential non-invasive biomarkers for detection of MB. circulation_biomarker_diagnosis_ns hsa-mir-151 Cardiovascular Diseases [unspecific] 24874084 We have demonstrated that this panel of five serum miRNAs is expected to become potential non-invasive biomarkers for detection of MB. circulation_biomarker_diagnosis_ns hsa-mir-29b Cardiovascular Diseases [unspecific] 24874084 We have demonstrated that this panel of five serum miRNAs is expected to become potential non-invasive biomarkers for detection of MB. circulation_biomarker_diagnosis_ns hsa-mir-503 Cardiovascular Diseases [unspecific] 24874084 We have demonstrated that this panel of five serum miRNAs is expected to become potential non-invasive biomarkers for detection of MB. circulation_biomarker_diagnosis_ns hsa-mir-645 Cardiovascular Diseases [unspecific] 24874084 We have demonstrated that this panel of five serum miRNAs is expected to become potential non-invasive biomarkers for detection of MB. circulation_biomarker_diagnosis_ns hsa-mir-483 "Carcinoma, Nasopharyngeal" 24874644 Plasma microRNA profiling in nasopharyngeal carcinoma patients reveals miR-548q and miR-483-5p as potential biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-548q "Carcinoma, Nasopharyngeal" 24874644 Plasma microRNA profiling in nasopharyngeal carcinoma patients reveals miR-548q and miR-483-5p as potential biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-19 Prostate Neoplasms 24893170 "miR-19, miR-345, miR-519c-5p serum levels predict adverse pathology in prostate cancer patients eligible for active surveillance." circulation_biomarker_diagnosis_ns hsa-mir-345 Prostate Neoplasms 24893170 "miR-19, miR-345, miR-519c-5p serum levels predict adverse pathology in prostate cancer patients eligible for active surveillance." circulation_biomarker_diagnosis_ns hsa-mir-519c Prostate Neoplasms 24893170 "miR-19, miR-345, miR-519c-5p serum levels predict adverse pathology in prostate cancer patients eligible for active surveillance." circulation_biomarker_diagnosis_ns hsa-mir-143 Psoriasis 24909097 "We suggest that changes in the miR-223 and miR-143 expressions in PBMCs from patients with psoriasis may serve as novel biomarkers for disease activity in psoriasis; however, further investigations are warranted to clarify their specific roles." circulation_biomarker_diagnosis_ns hsa-mir-223 Psoriasis 24909097 "We suggest that changes in the miR-223 and miR-143 expressions in PBMCs from patients with psoriasis may serve as novel biomarkers for disease activity in psoriasis; however, further investigations are warranted to clarify their specific roles." circulation_biomarker_diagnosis_ns hsa-mir-138 Ovarian Neoplasms 24911418 our study suggests that detecting these ovarian cancer specific miRNAs in plasma might serve as novel non-invasive biomarkers for ovarian cancer. circulation_biomarker_diagnosis_ns hsa-mir-126 Diabetes Mellitus 24927146 The role of circulating microRNA-126 (miR-126): a novel biomarker for screening prediabetes and newly diagnosed type 2 diabetes mellitus. circulation_biomarker_diagnosis_ns hsa-mir-200c Gastric Neoplasms 24947260 "GDF15 and MMP7 serum levels have diagnostic value for GC. The combination marker formed by GDF15, MMP7 and miR-200c is indicative of adverse evolution in GC patients." circulation_biomarker_diagnosis_ns hsa-mir-146a "Leukemia, Lymphoblastic, Acute" 24955371 these miRNAs not only may be used as biomarkers in diagnosis of ALL and monitoring the disease but also provide new insights into the potential roles of them in leukemogenesis. circulation_biomarker_diagnosis_ns hsa-mir-155 "Leukemia, Lymphoblastic, Acute" 24955371 these miRNAs not only may be used as biomarkers in diagnosis of ALL and monitoring the disease but also provide new insights into the potential roles of them in leukemogenesis. circulation_biomarker_diagnosis_ns hsa-mir-195 "Leukemia, Lymphoblastic, Acute" 24955371 these miRNAs not only may be used as biomarkers in diagnosis of ALL and monitoring the disease but also provide new insights into the potential roles of them in leukemogenesis. circulation_biomarker_diagnosis_ns hsa-mir-152 Bladder Neoplasms 24961907 expression level of serum miR-152 could provide information on the recurrence risk of NMIBC. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Hepatocellular" 24963487 Expression of serum exosomal microRNA-21 in human hepatocellular carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Esophageal" 24968850 "Both salivary and plasmatic miR-21 can be sensitive biomarkers for EC, and salivary miR-21 detection has the potential to replace plasma detection for EC diagnosis." circulation_biomarker_diagnosis_ns hsa-mir-23a "Diabetes Mellitus, Type 2" 24981880 "Serum miR-23a, a potential biomarker for diagnosis of pre-diabetes and type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-107 Breast Neoplasms 25004125 "A panel of 4 circulating miRNAs exhibited significantly altered levels following radical resection of primary ER+ breast cancers in post-menopausal women. These specific miRNAs may be involved in tumorigenesis and could potentially be used to monitor whether all cancer cells have been removed at surgery and/or, subsequently, whether the patients develop recurrence." circulation_biomarker_diagnosis_ns hsa-mir-148a Breast Neoplasms 25004125 "A panel of 4 circulating miRNAs exhibited significantly altered levels following radical resection of primary ER+ breast cancers in post-menopausal women. These specific miRNAs may be involved in tumorigenesis and could potentially be used to monitor whether all cancer cells have been removed at surgery and/or, subsequently, whether the patients develop recurrence." circulation_biomarker_diagnosis_ns hsa-mir-223 Breast Neoplasms 25004125 "A panel of 4 circulating miRNAs exhibited significantly altered levels following radical resection of primary ER+ breast cancers in post-menopausal women. These specific miRNAs may be involved in tumorigenesis and could potentially be used to monitor whether all cancer cells have been removed at surgery and/or, subsequently, whether the patients develop recurrence." circulation_biomarker_diagnosis_ns hsa-mir-338 Breast Neoplasms 25004125 "A panel of 4 circulating miRNAs exhibited significantly altered levels following radical resection of primary ER+ breast cancers in post-menopausal women. These specific miRNAs may be involved in tumorigenesis and could potentially be used to monitor whether all cancer cells have been removed at surgery and/or, subsequently, whether the patients develop recurrence." circulation_biomarker_diagnosis_ns hsa-mir-25 Pancreatic Neoplasms 25030590 "Plasma miR-21, miR-155, miR-25, miR-210 have diagnostic value for pancreatic cancer, and deserve further study." circulation_biomarker_diagnosis_ns hsa-mir-1301 Preeclampsia 25064070 miR-1301 is dysregulated in early-onset preeclampsia and could possibly play a role in the regulation of leptin during pregnancy. circulation_biomarker_diagnosis_ns hsa-mir-223 Preeclampsia 25064070 miR-1301 is dysregulated in early-onset preeclampsia and could possibly play a role in the regulation of leptin during pregnancy. circulation_biomarker_diagnosis_ns hsa-mir-224 Preeclampsia 25064070 miR-1301 is dysregulated in early-onset preeclampsia and could possibly play a role in the regulation of leptin during pregnancy. circulation_biomarker_diagnosis_ns hsa-mir-122 Hepatitis C Virus Infection 25065618 "miR-122, miR-126, miR-136 and miR-181a have been shown to be involved in HCV infection with different genotypes. Their expression has been associated with the gender, stage and grade of liver disease, mode of transmission, serum HCV load and the presence of steatosis." circulation_biomarker_diagnosis_ns hsa-mir-126 Hepatitis C Virus Infection 25065618 "miR-122, miR-126, miR-136 and miR-181a have been shown to be involved in HCV infection with different genotypes. Their expression has been associated with the gender, stage and grade of liver disease, mode of transmission, serum HCV load and the presence of steatosis." circulation_biomarker_diagnosis_ns hsa-mir-136 Hepatitis C Virus Infection 25065618 "miR-122, miR-126, miR-136 and miR-181a have been shown to be involved in HCV infection with different genotypes. Their expression has been associated with the gender, stage and grade of liver disease, mode of transmission, serum HCV load and the presence of steatosis." circulation_biomarker_diagnosis_ns hsa-mir-181a Hepatitis C Virus Infection 25065618 "miR-122, miR-126, miR-136 and miR-181a have been shown to be involved in HCV infection with different genotypes. Their expression has been associated with the gender, stage and grade of liver disease, mode of transmission, serum HCV load and the presence of steatosis." circulation_biomarker_diagnosis_ns hsa-mir-146a Sepsis 25086335 "So far, miR-223, miR-146a and miR-150 have been identified to have promising prognostic and diagnostic value to sepsis." circulation_biomarker_diagnosis_ns hsa-mir-150 Sepsis 25086335 "So far, miR-223, miR-146a and miR-150 have been identified to have promising prognostic and diagnostic value to sepsis." circulation_biomarker_diagnosis_ns hsa-mir-21 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 25099764 Combined detection of serum exosomal miR-21 and HOTAIR as diagnostic and prognostic biomarkers for laryngeal squamous cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-182 Colorectal Adenocarcinoma 25115394 Circulating miR-182 is a biomarker of colorectal adenocarcinoma progression. circulation_biomarker_diagnosis_ns hsa-mir-25 "Squamous Cell Carcinoma, Esophageal" 25117812 Plasma miR-25 might be a clinically useful biomarker for cancer detection and the monitoring of tumour dynamics in ESCC patients. circulation_biomarker_diagnosis_ns hsa-mir-193b Alzheimer Disease 25119742 MicroRNA-193b is a regulator of amyloid precursor protein in the blood and cerebrospinal fluid derived exosomal microRNA-193b is a biomarker of Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-375 Diabetes Mellitus 25120598 "Compared with the miR-375 levels in patients with normal glucose tolerance (NGT; n=53), the samples from patients with IGT (n=44) exhibited downregulation of miR-375, while those from patients with T2DM (n=54) exhibited upregulation of miR-375 in the plasma." circulation_biomarker_diagnosis_ns hsa-mir-222 Gastric Neoplasms 25129310 Circulating miR-222 in plasma and its potential diagnostic and prognostic value in gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-24 "Carcinoma, Hepatocellular" 25129312 Diagnostic and prognostic significance of serum miR-24-3p in HBV-related hepatocellular carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-124 Chronic Hepatitis B 25131617 Serum microRNA-124 is a novel biomarker for liver necroinflammation in patients with chronic hepatitis B virus infection. circulation_biomarker_diagnosis_ns hsa-mir-29 Chronic Hepatitis B 25138057 Serum miR-29 levels are negatively correlated with liver fibrotic stages and necroinflammation grades in patients with chronic HBV infection. miR-29 appears to be a novel biomarkers for predicting disease progression in these patients. circulation_biomarker_diagnosis_ns hsa-mir-1 Muscle Diseases [unspecific] 25146754 These miRNAs are potential biomarkers of muscle damage or adaptation to exercise. circulation_biomarker_diagnosis_ns hsa-mir-1 "Muscular Dystrophy, Duchenne" 25150707 "Taken together, our data demonstrate that levels of miR-1, miR-133a, and miR-206 in serum of BMD and miR-1 in sera of LGMD and FSHD patients showed no significant differences compared with those of controls by Bonferroni correction. However, the results might need increase in sample sizes to evaluate these three miRNAs as variable biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-133a "Muscular Dystrophy, Duchenne" 25150707 "Taken together, our data demonstrate that levels of miR-1, miR-133a, and miR-206 in serum of BMD and miR-1 in sera of LGMD and FSHD patients showed no significant differences compared with those of controls by Bonferroni correction. However, the results might need increase in sample sizes to evaluate these three miRNAs as variable biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-206 "Muscular Dystrophy, Duchenne" 25150707 "Taken together, our data demonstrate that levels of miR-1, miR-133a, and miR-206 in serum of BMD and miR-1 in sera of LGMD and FSHD patients showed no significant differences compared with those of controls by Bonferroni correction. However, the results might need increase in sample sizes to evaluate these three miRNAs as variable biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-196a "Scleroderma, Localized" 25152444 Down-regulation of miR-196a and subsequent overexpression of type 1 collagen in dermal fibroblasts may play a key role in the pathogenesis of LSc. The serum levels of miR-196a may be useful as a diagnostic marker of LSc. circulation_biomarker_diagnosis_ns hsa-mir-21 "Squamous Cell Carcinoma, Oral" 25174622 Circulating microRNA-21 (MIR-21) and phosphatase and tensin homolog (PTEN) are promising novel biomarkers for detection of oral squamous cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-148a Osteosarcoma 25185654 Circulating miR-148a is a significant diagnostic and prognostic biomarker for patients with osteosarcoma. circulation_biomarker_diagnosis_ns hsa-mir-371a Germ Cell Tumor 25187505 MicroRNA miR-371a-3p in serum of patients with germ cell tumours: evaluations for establishing a serum biomarker. circulation_biomarker_diagnosis_ns hsa-mir-192 Choriocarcinoma 25202432 "Normalization of miR-98 expression levels to those of U6 snRNA, miR-192 or a combination of these genes enabled the detection of a significant difference between BPE and LA-MPE samples." circulation_biomarker_diagnosis_ns hsa-mir-708 "Leukemia, Lymphoblastic, Acute, Childhood" 25214155 MiR-708-5p is differentially expressed in childhood acute lymphoblastic leukemia but not strongly associated to clinical features. circulation_biomarker_diagnosis_ns hsa-mir-483 Myeloma 25216866 Circulating microRNA 483-5p as a novel biomarker for diagnosis survival prediction in multiple myeloma. circulation_biomarker_diagnosis_ns hsa-mir-106b Gastric Neoplasms 25218271 MicroRNA-106b~25 expressions in tumor tissues and plasma of patients with gastric cancers. circulation_biomarker_diagnosis_ns hsa-mir-186 Focal Segmental Glomerulosclerosis 25218681 Plasma miR-186 may be a biomarker for FSGS with nephrotic proteinuria. circulation_biomarker_diagnosis_ns hsa-mir-155 Systemic Lupus Erythematosus 25253569 Correcting the expression of miRNA-155 represses PP2Ac and enhances the release of IL-2 in PBMCs of juvenile SLE patients. circulation_biomarker_diagnosis_ns hsa-mir-146a Sepsis 25265569 "miR-182, miR-143, miR-145, miR-146a, miR-150, and miR-155 were dysregulated in sepsis patients." circulation_biomarker_diagnosis_ns hsa-mir-199a Colorectal Carcinoma 25269744 Circulating miR-199a-3p as a novel serum biomarker for colorectal cancer. circulation_biomarker_diagnosis_ns hsa-mir-335 "Leukemia, Myeloid, Acute" 25301405 Our data offer the convincing evidence for the first time that serum miR-335 level may be markedly and consistently increased in pediatric AML patients. Serum miR-335 may serve as a promising marker for monitoring the progression and predicting the clinical outcome of patients with this disease. circulation_biomarker_diagnosis_ns hsa-mir-182 Pancreatic Neoplasms 25326859 Circulating microRNA-182 in plasma and its potential diagnostic and prognostic value for pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-126 Coronary Artery Disease 25327597 "Plasma miR-126 level is positively correlated to the CCC formation and is an independent predictor of CCC development in patients with severely narrowed coronary arteries, suggesting that plasma miR-126 might be a useful new, stable blood biomarker for predicting CCC formation in patients with severely narrowed coronary arteries." circulation_biomarker_diagnosis_ns hsa-mir-126 Coronary Artery Disease 25349183 "In contrast, increased expression of miR-126 and miR-199a in circulating MVs was significantly associated with a lower major adverse CV event rate." circulation_biomarker_diagnosis_ns hsa-mir-24 Heart Failure 25364765 miR-24 and miR-214 are bi-functional cardio-miRs. circulation_biomarker_diagnosis_ns hsa-mir-29 Glioma 25367878 Identification and Evaluation of Serum MicroRNA-29 Family for Glioma Screening. circulation_biomarker_diagnosis_ns hsa-mir-19a Acute Myocardial Infarction 25383678 Circulating microRNA-19a as a potential novel biomarker for diagnosis of acute myocardial infarction. circulation_biomarker_diagnosis_ns hsa-mir-17 "Carcinoma, Hepatocellular" 25391771 "miR-30c-5p, miR-223-3p, miR-302c-3p and miR-17-8p could be used as novel non-invasive biomarkers of HCV-positive HCC in very early, even at cirrhosis stage of liver disease." circulation_biomarker_diagnosis_ns hsa-mir-206 "Carcinoma, Hepatocellular" 25391771 "miR-30c-5p, miR-223-3p, miR-302c-3p and miR-17-9p could be used as novel non-invasive biomarkers of HCV-positive HCC in very early, even at cirrhosis stage of liver disease." circulation_biomarker_diagnosis_ns hsa-mir-223 "Carcinoma, Hepatocellular" 25391771 "miR-30c-5p, miR-223-3p, miR-302c-3p and miR-17-6p could be used as novel non-invasive biomarkers of HCV-positive HCC in very early, even at cirrhosis stage of liver disease." circulation_biomarker_diagnosis_ns hsa-mir-302c "Carcinoma, Hepatocellular" 25391771 "miR-30c-5p, miR-223-3p, miR-302c-3p and miR-17-7p could be used as novel non-invasive biomarkers of HCV-positive HCC in very early, even at cirrhosis stage of liver disease." circulation_biomarker_diagnosis_ns hsa-mir-30c "Carcinoma, Hepatocellular" 25391771 "miR-30c-5p, miR-223-3p, miR-302c-3p and miR-17-5p could be used as novel non-invasive biomarkers of HCV-positive HCC in very early, even at cirrhosis stage of liver disease." circulation_biomarker_diagnosis_ns hsa-mir-142 Systemic Lupus Erythematosus 25399392 "Circulating miRNA profiles are characteristic for SSc compared with both HC and SLE cases. Some of the predicted targets of the differentially regulated miRNA are of relevance for transforming growth factor-¦Â signaling andfibrosis, but need to be validated in independent studies." circulation_biomarker_diagnosis_ns hsa-mir-150 Systemic Lupus Erythematosus 25399392 "Circulating miRNA profiles are characteristic for SSc compared with both HC and SLE cases. Some of the predicted targets of the differentially regulated miRNA are of relevance for transforming growth factor-¦Â signaling andfibrosis, but need to be validated in independent studies." circulation_biomarker_diagnosis_ns hsa-mir-16 Systemic Lupus Erythematosus 25399392 "Circulating miRNA profiles are characteristic for SSc compared with both HC and SLE cases. Some of the predicted targets of the differentially regulated miRNA are of relevance for transforming growth factor-¦Â signaling andfibrosis, but need to be validated in independent studies." circulation_biomarker_diagnosis_ns hsa-mir-223 Systemic Lupus Erythematosus 25399392 "Circulating miRNA profiles are characteristic for SSc compared with both HC and SLE cases. Some of the predicted targets of the differentially regulated miRNA are of relevance for transforming growth factor-¦Â signaling andfibrosis, but need to be validated in independent studies." circulation_biomarker_diagnosis_ns hsa-mir-638 Systemic Lupus Erythematosus 25399392 "Circulating miRNA profiles are characteristic for SSc compared with both HC and SLE cases. Some of the predicted targets of the differentially regulated miRNA are of relevance for transforming growth factor-¦Â signaling andfibrosis, but need to be validated in independent studies." circulation_biomarker_diagnosis_ns hsa-mir-125b Colorectal Carcinoma 25405754 "The measured levels of miRNAs in serum and plasma from same patients varied in the presence of hemolysis, and since hemolysis and other factors affected miRNA expression, it is important to consider these confounders while developing miRNA-based diagnostic assays." circulation_biomarker_diagnosis_ns hsa-mir-16 Colorectal Carcinoma 25405754 "The measured levels of miRNAs in serum and plasma from same patients varied in the presence of hemolysis, and since hemolysis and other factors affected miRNA expression, it is important to consider these confounders while developing miRNA-based diagnostic assays." circulation_biomarker_diagnosis_ns hsa-mir-21 Colorectal Carcinoma 25405754 "The measured levels of miRNAs in serum and plasma from same patients varied in the presence of hemolysis, and since hemolysis and other factors affected miRNA expression, it is important to consider these confounders while developing miRNA-based diagnostic assays." circulation_biomarker_diagnosis_ns hsa-mir-29a Colorectal Carcinoma 25405754 "The measured levels of miRNAs in serum and plasma from same patients varied in the presence of hemolysis, and since hemolysis and other factors affected miRNA expression, it is important to consider these confounders while developing miRNA-based diagnostic assays." circulation_biomarker_diagnosis_ns hsa-mir-124 Neoplasms [unspecific] 25416717 "This study describes a pipeline for robust diagnostic serum miRNA profiling in childhood solid tumors, and has identified candidate miRNA profiles for prospective testing." circulation_biomarker_diagnosis_ns hsa-mir-1538 Neoplasms [unspecific] 25416717 "This study describes a pipeline for robust diagnostic serum miRNA profiling in childhood solid tumors, and has identified candidate miRNA profiles for prospective testing." circulation_biomarker_diagnosis_ns hsa-mir-218 Neoplasms [unspecific] 25416717 "This study describes a pipeline for robust diagnostic serum miRNA profiling in childhood solid tumors, and has identified candidate miRNA profiles for prospective testing." circulation_biomarker_diagnosis_ns hsa-mir-490 Neoplasms [unspecific] 25416717 "This study describes a pipeline for robust diagnostic serum miRNA profiling in childhood solid tumors, and has identified candidate miRNA profiles for prospective testing." circulation_biomarker_diagnosis_ns hsa-mir-9 Neoplasms [unspecific] 25416717 "This study describes a pipeline for robust diagnostic serum miRNA profiling in childhood solid tumors, and has identified candidate miRNA profiles for prospective testing." circulation_biomarker_diagnosis_ns hsa-mir-1179 Proliferative Diabetic Retinopathy 25427542 "serum miRNAs have the potential to be sensitive, cost-effective biomarkers for the early detection of PDR. These biomarkers could serve as a dynamic monitoring factor for detecting the progression of PDR from NPDR." circulation_biomarker_diagnosis_ns hsa-mir-181c Proliferative Diabetic Retinopathy 25427542 "serum miRNAs have the potential to be sensitive, cost-effective biomarkers for the early detection of PDR. These biomarkers could serve as a dynamic monitoring factor for detecting the progression of PDR from NPDR." circulation_biomarker_diagnosis_ns hsa-mir-21 Proliferative Diabetic Retinopathy 25427542 "serum miRNAs have the potential to be sensitive, cost-effective biomarkers for the early detection of PDR. These biomarkers could serve as a dynamic monitoring factor for detecting the progression of PDR from NPDR." circulation_biomarker_diagnosis_ns hsa-mir-320a Macroglobulinemia 25428891 Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenstr?m macroglobulinemia. circulation_biomarker_diagnosis_ns hsa-mir-320b Macroglobulinemia 25428891 Combination of serum microRNA-320a and microRNA-321b as a marker for Waldenstr?m macroglobulinemia. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Breast" 25431259 "MiR-21 has a relatively high diagnostic value for detecting breast cancer, and miR-21 assays based on plasma, serum, and tissue achieved relatively higher accuracy" circulation_biomarker_diagnosis_ns hsa-mir-21 Neoplasms [unspecific] 25431259 "MiR-21 has a relatively high diagnostic value for detecting breast cancer, and miR-21 assays based on plasma, serum, and tissue achieved relatively higher accuracy" circulation_biomarker_diagnosis_ns hsa-mir-505 Hypertension 25449503 "hsa-mir-505 is a novel circulating signature of hypertension, which may play a role in angiogenesis. Our results provide mechanistic insights into hypertension-associated pathogenesis and point " circulation_biomarker_diagnosis_ns hsa-mir-122 Hepatitis B Virus Infection 25452043 Serum microRNA levels reflect differences in the etiology and stage of viral hepatitis. circulation_biomarker_diagnosis_ns hsa-mir-125b Hepatitis B Virus Infection 25452043 Serum microRNA levels reflect differences in the etiology and stage of viral hepatitis. circulation_biomarker_diagnosis_ns hsa-mir-1275 Hepatitis B Virus Infection 25452043 Serum microRNA levels reflect differences in the etiology and stage of viral hepatitis. circulation_biomarker_diagnosis_ns hsa-mir-22 Hepatitis B Virus Infection 25452043 Serum microRNA levels reflect differences in the etiology and stage of viral hepatitis. circulation_biomarker_diagnosis_ns hsa-mir-720 Hepatitis B Virus Infection 25452043 Serum microRNA levels reflect differences in the etiology and stage of viral hepatitis. circulation_biomarker_diagnosis_ns hsa-mir-99a Hepatitis B Virus Infection 25452043 Serum microRNA levels reflect differences in the etiology and stage of viral hepatitis. circulation_biomarker_diagnosis_ns hsa-mir-146b Thyroid Neoplasms 25456009 miR-146b and miR-155 helped to discriminate between benign and malignant lesions. Circulating miRNA is likely a useful alternate serological marker for PTC. This preliminary study suggested that circulating miRNAs may be useful as follow-up tools as well as diagnostic tools. circulation_biomarker_diagnosis_ns hsa-mir-155 Thyroid Neoplasms 25456009 miR-146b and miR-155 helped to discriminate between benign and malignant lesions. Circulating miRNA is likely a useful alternate serological marker for PTC. This preliminary study suggested that circulating miRNAs may be useful as follow-up tools as well as diagnostic tools. circulation_biomarker_diagnosis_ns hsa-mir-29 Endomyocardial Fibrosis 25457410 "Reply: MicroRNA-29, a mysterious regulator in myocardial fibrosis and circulating miR-29a as a biomarker." circulation_biomarker_diagnosis_ns hsa-mir-21 Glomerulonephritis 25468389 "Furthermore, the glomerular and serum levels of miR-21, a putative microRNA ligand of TLR8, were higher in BXSB-Yaa mice than in BXSB mice." circulation_biomarker_diagnosis_ns hsa-mir-150 Intrahepatic Cholangiocarcinoma 25482320 "combination of these two markers improved the power of screening ICC. Moreover, on the basis of the plasma miR-150 level, 15 ICC patients were divided into a low or high expression group. We found that plasma miR-150 is a potential diagnostic biomarker for ICC." circulation_biomarker_diagnosis_ns hsa-mir-196a Oral Neoplasms 25485932 Combined determination of circulating miR-196a and miR-196b levels may serve as panel plasma biomarkers for the early detection of oral cancer. circulation_biomarker_diagnosis_ns hsa-mir-196b Oral Neoplasms 25485932 Combined determination of circulating miR-196a and miR-196b levels may serve as panel plasma biomarkers for the early detection of oral cancer. circulation_biomarker_diagnosis_ns hsa-mir-132 Schizophrenia 25487174 "miRNA expression is more significant in plasma than in PBMC, and suggest that miR-30e in plasma may be a more sensitive biomarker for schizophrenia diagnosis, although its aberrant expression can be detected in both plasma and PBMC." circulation_biomarker_diagnosis_ns hsa-mir-181b Schizophrenia 25487174 "miRNA expression is more significant in plasma than in PBMC, and suggest that miR-30e in plasma may be a more sensitive biomarker for schizophrenia diagnosis, although its aberrant expression can be detected in both plasma and PBMC." circulation_biomarker_diagnosis_ns hsa-mir-195 Schizophrenia 25487174 "miRNA expression is more significant in plasma than in PBMC, and suggest that miR-30e in plasma may be a more sensitive biomarker for schizophrenia diagnosis, although its aberrant expression can be detected in both plasma and PBMC." circulation_biomarker_diagnosis_ns hsa-mir-212 Schizophrenia 25487174 "miRNA expression is more significant in plasma than in PBMC, and suggest that miR-30e in plasma may be a more sensitive biomarker for schizophrenia diagnosis, although its aberrant expression can be detected in both plasma and PBMC." circulation_biomarker_diagnosis_ns hsa-mir-30e Schizophrenia 25487174 "miRNA expression is more significant in plasma than in PBMC, and suggest that miR-30e in plasma may be a more sensitive biomarker for schizophrenia diagnosis, although its aberrant expression can be detected in both plasma and PBMC." circulation_biomarker_diagnosis_ns hsa-mir-346 Schizophrenia 25487174 "miRNA expression is more significant in plasma than in PBMC, and suggest that miR-30e in plasma may be a more sensitive biomarker for schizophrenia diagnosis, although its aberrant expression can be detected in both plasma and PBMC." circulation_biomarker_diagnosis_ns hsa-mir-34a Schizophrenia 25487174 "miRNA expression is more significant in plasma than in PBMC, and suggest that miR-30e in plasma may be a more sensitive biomarker for schizophrenia diagnosis, although its aberrant expression can be detected in both plasma and PBMC." circulation_biomarker_diagnosis_ns hsa-mir-432 Schizophrenia 25487174 "miRNA expression is more significant in plasma than in PBMC, and suggest that miR-30e in plasma may be a more sensitive biomarker for schizophrenia diagnosis, although its aberrant expression can be detected in both plasma and PBMC." circulation_biomarker_diagnosis_ns hsa-mir-7 Schizophrenia 25487174 "miRNA expression is more significant in plasma than in PBMC, and suggest that miR-30e in plasma may be a more sensitive biomarker for schizophrenia diagnosis, although its aberrant expression can be detected in both plasma and PBMC." circulation_biomarker_diagnosis_ns hsa-mir-148a Lung Neoplasms 25501703 miRNAs have great potential to serve as promising novel biomarkers in NSCLC screening. Further large-scale studies are needed to validate our results. circulation_biomarker_diagnosis_ns hsa-mir-148b Lung Neoplasms 25501703 miRNAs have great potential to serve as promising novel biomarkers in NSCLC screening. Further large-scale studies are needed to validate our results. circulation_biomarker_diagnosis_ns hsa-mir-152 Lung Neoplasms 25501703 miRNAs have great potential to serve as promising novel biomarkers in NSCLC screening. Further large-scale studies are needed to validate our results. circulation_biomarker_diagnosis_ns hsa-mir-21 Lung Neoplasms 25501703 miRNAs have great potential to serve as promising novel biomarkers in NSCLC screening. Further large-scale studies are needed to validate our results. circulation_biomarker_diagnosis_ns hsa-mir-377 "Leukemia, Myeloid, Acute" 25502508 a miRNA signature in human cord blood stem and progenitor cells with a potential role in hematopoietic stemness properties and possibly in leukemogenesis of specific AML subtypes. circulation_biomarker_diagnosis_ns hsa-mir-4739 "Leukemia, Myeloid, Acute" 25502508 a miRNA signature in human cord blood stem and progenitor cells with a potential role in hematopoietic stemness properties and possibly in leukemogenesis of specific AML subtypes. circulation_biomarker_diagnosis_ns hsa-mir-142 "Lymphoma, T-Cell" 25503151 miR profiling in CTCL may be a key to improving both diagnosis and risk prediction. circulation_biomarker_diagnosis_ns hsa-mir-146b "Lymphoma, T-Cell" 25503151 miR profiling in CTCL may be a key to improving both diagnosis and risk prediction. circulation_biomarker_diagnosis_ns hsa-mir-155 "Lymphoma, T-Cell" 25503151 miR profiling in CTCL may be a key to improving both diagnosis and risk prediction. circulation_biomarker_diagnosis_ns hsa-mir-16 "Lymphoma, T-Cell" 25503151 miR profiling in CTCL may be a key to improving both diagnosis and risk prediction. circulation_biomarker_diagnosis_ns hsa-mir-21 "Lymphoma, T-Cell" 25503151 miR profiling in CTCL may be a key to improving both diagnosis and risk prediction. circulation_biomarker_diagnosis_ns hsa-mir-342 "Lymphoma, T-Cell" 25503151 miR profiling in CTCL may be a key to improving both diagnosis and risk prediction. circulation_biomarker_diagnosis_ns hsa-mir-92a "Lymphoma, T-Cell" 25503151 miR profiling in CTCL may be a key to improving both diagnosis and risk prediction. circulation_biomarker_diagnosis_ns hsa-mir-93 "Lymphoma, T-Cell" 25503151 miR profiling in CTCL may be a key to improving both diagnosis and risk prediction. circulation_biomarker_diagnosis_ns hsa-mir-16 Chronic Hepatitis C 25505813 "the expression levels of miR-16, miR-193b, miR-199a, miR-222, and miR-324 target miRNAs in PBMCs of CHC may act as significant risk biomarkers for the development of CHC." circulation_biomarker_diagnosis_ns hsa-mir-193b Chronic Hepatitis C 25505813 "the expression levels of miR-16, miR-193b, miR-199a, miR-222, and miR-324 target miRNAs in PBMCs of CHC may act as significant risk biomarkers for the development of CHC." circulation_biomarker_diagnosis_ns hsa-mir-199a Chronic Hepatitis C 25505813 "the expression levels of miR-16, miR-193b, miR-199a, miR-222, and miR-324 target miRNAs in PBMCs of CHC may act as significant risk biomarkers for the development of CHC." circulation_biomarker_diagnosis_ns hsa-mir-222 Chronic Hepatitis C 25505813 "the expression levels of miR-16, miR-193b, miR-199a, miR-222, and miR-324 target miRNAs in PBMCs of CHC may act as significant risk biomarkers for the development of CHC." circulation_biomarker_diagnosis_ns hsa-mir-324 Chronic Hepatitis C 25505813 "the expression levels of miR-16, miR-193b, miR-199a, miR-222, and miR-324 target miRNAs in PBMCs of CHC may act as significant risk biomarkers for the development of CHC." circulation_biomarker_diagnosis_ns hsa-mir-21 Breast Neoplasms 25516467 "miR-21 is a potential biomarker for early diagnosis of breast cancer with high sensitivity and specificity, and its clinical application warrants further investigation" circulation_biomarker_diagnosis_ns hsa-mir-200a "Carcinoma, Hepatocellular, HBV-Related" 25519019 "only in the HCC group, miR-18a, miR-100, miR-145 and miR-223 were up-regulated 3.48-, 2.95-, 2.12- and 3.91-fold, respectively, and miR-200a and miR-222 were down-regulated 2.56- and 2.00-fold, respectively." circulation_biomarker_diagnosis_ns hsa-let-7c Prostate Neoplasms 25521481 the combination of the studied circulating plasma miRNAs and serum PSA has the potential to be used as a noninvasive diagnostic biomarker for PC screening outperforming the PSA testing alone. circulation_biomarker_diagnosis_ns hsa-mir-141 Prostate Neoplasms 25521481 the combination of the studied circulating plasma miRNAs and serum PSA has the potential to be used as a noninvasive diagnostic biomarker for PC screening outperforming the PSA testing alone. circulation_biomarker_diagnosis_ns hsa-mir-30c Prostate Neoplasms 25521481 the combination of the studied circulating plasma miRNAs and serum PSA has the potential to be used as a noninvasive diagnostic biomarker for PC screening outperforming the PSA testing alone. circulation_biomarker_diagnosis_ns hsa-mir-375 Prostate Neoplasms 25521481 the combination of the studied circulating plasma miRNAs and serum PSA has the potential to be used as a noninvasive diagnostic biomarker for PC screening outperforming the PSA testing alone. circulation_biomarker_diagnosis_ns hsa-mir-21 Colorectal Carcinoma 25524942 Circulating miR-21 may be a suitable diagnostic biomarker for CRC with moderate sensitivity and specificity. Further studies should evaluate the diagnostic value of miR-21 for CRC in the future. circulation_biomarker_diagnosis_ns hsa-mir-21 Neoplasms [unspecific] 25527152 the circulating miR-21 may be a potential biomarker as diagnostic tool for early-stage cancer diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-182 "Diabetes Mellitus, Type 2" 25530976 miR-182 can be a biomarker in diagnosis of the potential T2D that has benefits for medical purpose. circulation_biomarker_diagnosis_ns hsa-mir-192 Prediabetes 25532038 "the pattern of circulating miRNAs is modified by defects in glucose metabolism in a similar manner in mice and humans. This circulating miRNA signature for prediabetes could be used as a new diagnostic tool, as well as to monitor response to intervention." circulation_biomarker_diagnosis_ns hsa-mir-193b Prediabetes 25532038 "the pattern of circulating miRNAs is modified by defects in glucose metabolism in a similar manner in mice and humans. This circulating miRNA signature for prediabetes could be used as a new diagnostic tool, as well as to monitor response to intervention." circulation_biomarker_diagnosis_ns hsa-mir-16 Multiple Myeloma 25593199 A serum microRNA signature associated with complete remission and progression after autologous stem-cell transplantation in patients with multiple myeloma. circulation_biomarker_diagnosis_ns hsa-mir-17 Multiple Myeloma 25593199 A serum microRNA signature associated with complete remission and progression after autologous stem-cell transplantation in patients with multiple myeloma. circulation_biomarker_diagnosis_ns hsa-mir-19b Multiple Myeloma 25593199 A serum microRNA signature associated with complete remission and progression after autologous stem-cell transplantation in patients with multiple myeloma. circulation_biomarker_diagnosis_ns hsa-mir-20a Multiple Myeloma 25593199 A serum microRNA signature associated with complete remission and progression after autologous stem-cell transplantation in patients with multiple myeloma. circulation_biomarker_diagnosis_ns hsa-mir-25 Multiple Myeloma 25593199 A serum microRNA signature associated with complete remission and progression after autologous stem-cell transplantation in patients with multiple myeloma. circulation_biomarker_diagnosis_ns hsa-mir-331 Multiple Myeloma 25593199 A serum microRNA signature associated with complete remission and progression after autologous stem-cell transplantation in patients with multiple myeloma. circulation_biomarker_diagnosis_ns hsa-mir-660 Multiple Myeloma 25593199 A serum microRNA signature associated with complete remission and progression after autologous stem-cell transplantation in patients with multiple myeloma. circulation_biomarker_diagnosis_ns hsa-mir-199a "Carcinoma, Hepatocellular" 25618599 "circulating miR-199a-3p showed better predictive value in patients with long-term drinking. Our data suggested that circulating miR-375 and miR-199a-3p could be a novel serum biomarker for HCC. Nevertheless, further validating and improving study with larger sample should be conducted to confirm our results." circulation_biomarker_diagnosis_ns hsa-mir-375 "Carcinoma, Hepatocellular" 25618599 "circulating miR-199a-3p showed better predictive value in patients with long-term drinking. Our data suggested that circulating miR-375 and miR-199a-3p could be a novel serum biomarker for HCC. Nevertheless, further validating and improving study with larger sample should be conducted to confirm our results." circulation_biomarker_diagnosis_ns hsa-mir-125a Heart Failure 25619197 "Of these, miR-1233, -183-3p, -190a, -193b-3p, -193b-5p, -211-5p, -494, and -671-5p distinguished HF from controls." circulation_biomarker_diagnosis_ns hsa-mir-211 Heart Failure 25619197 "Of these, miR-1233, -183-3p, -190a, -193b-3p, -193b-5p, -211-5p, -494, and -671-5p distinguished HF from controls." circulation_biomarker_diagnosis_ns hsa-let-7a "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-let-7b "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-let-7c "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-let-7f "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-10a "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-1244 "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-135 "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-141 "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-16 "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-182 "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-200b "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-205 "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-429 "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-520b "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-96 "Carcinoma, Urothelial, Upper Tract" 25629698 MicroRNA expression is altered in UUTUC. The analysis of circulating miR-141 may be useful to identify patients with UUTUC. circulation_biomarker_diagnosis_ns hsa-mir-143 Obesity 25637573 Obesity leads to alterations in miRNA expressions and miRNA-143 and -223s can be used as biomarkers for the metabolic changes in obesity. circulation_biomarker_diagnosis_ns hsa-mir-223 Obesity 25637573 Obesity leads to alterations in miRNA expressions and miRNA-143 and -223s can be used as biomarkers for the metabolic changes in obesity. circulation_biomarker_diagnosis_ns hsa-mir-125a Lung Neoplasms 25639977 the panel of miRNA biomarkers had the potential for the early detection of lung cancer. circulation_biomarker_diagnosis_ns hsa-mir-126 Lung Neoplasms 25639977 the panel of miRNA biomarkers had the potential for the early detection of lung cancer. circulation_biomarker_diagnosis_ns hsa-mir-25 Lung Neoplasms 25639977 the panel of miRNA biomarkers had the potential for the early detection of lung cancer. circulation_biomarker_diagnosis_ns hsa-mir-132 Schizophrenia 25656957 A preliminary analysis of microRNA as potential clinical biomarker for schizophrenia. circulation_biomarker_diagnosis_ns hsa-mir-181b Schizophrenia 25656957 A preliminary analysis of microRNA as potential clinical biomarker for schizophrenia. circulation_biomarker_diagnosis_ns hsa-mir-212 Schizophrenia 25656957 A preliminary analysis of microRNA as potential clinical biomarker for schizophrenia. circulation_biomarker_diagnosis_ns hsa-mir-30e Schizophrenia 25656957 A preliminary analysis of microRNA as potential clinical biomarker for schizophrenia. circulation_biomarker_diagnosis_ns hsa-mir-346 Schizophrenia 25656957 A preliminary analysis of microRNA as potential clinical biomarker for schizophrenia. circulation_biomarker_diagnosis_ns hsa-mir-432 Schizophrenia 25656957 A preliminary analysis of microRNA as potential clinical biomarker for schizophrenia. circulation_biomarker_diagnosis_ns hsa-mir-149 Coronary Artery Disease 25664324 Circulating miR-765 and miR-149: potential noninvasive diagnostic biomarkers for geriatric coronary artery disease patients. circulation_biomarker_diagnosis_ns hsa-mir-765 Coronary Artery Disease 25664324 Circulating miR-765 and miR-149: potential noninvasive diagnostic biomarkers for geriatric coronary artery disease patients. circulation_biomarker_diagnosis_ns hsa-mir-223 Allergic Rhinitis 25675113 Serum hsa-miR-223 was significantly up-regulated in postseason compared with preseason samples. circulation_biomarker_diagnosis_ns hsa-mir-103 "Diabetes Mellitus, Type 2" 25677225 "This meta-analysis confirms that 40 miRNAs are significantly dysregulated in type 2 diabetes. miR-29a, miR-34a, miR-375,miR-103, miR-107, miR-132, miR-142-3p and miR-144 are potential circulating biomarkers of type 2 diabetes. In addition, miR-199a-3p and miR-223 are potential tissue biomarkers of type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-107 "Diabetes Mellitus, Type 2" 25677225 "This meta-analysis confirms that 40 miRNAs are significantly dysregulated in type 2 diabetes. miR-29a, miR-34a, miR-375,miR-103, miR-107, miR-132, miR-142-3p and miR-144 are potential circulating biomarkers of type 2 diabetes. In addition, miR-199a-3p and miR-223 are potential tissue biomarkers of type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-132 "Diabetes Mellitus, Type 2" 25677225 "This meta-analysis confirms that 40 miRNAs are significantly dysregulated in type 2 diabetes. miR-29a, miR-34a, miR-375,miR-103, miR-107, miR-132, miR-142-3p and miR-144 are potential circulating biomarkers of type 2 diabetes. In addition, miR-199a-3p and miR-223 are potential tissue biomarkers of type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-142 "Diabetes Mellitus, Type 2" 25677225 "This meta-analysis confirms that 40 miRNAs are significantly dysregulated in type 2 diabetes. miR-29a, miR-34a, miR-375,miR-103, miR-107, miR-132, miR-142-3p and miR-144 are potential circulating biomarkers of type 2 diabetes. In addition, miR-199a-3p and miR-223 are potential tissue biomarkers of type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-144 "Diabetes Mellitus, Type 2" 25677225 "This meta-analysis confirms that 40 miRNAs are significantly dysregulated in type 2 diabetes. miR-29a, miR-34a, miR-375,miR-103, miR-107, miR-132, miR-142-3p and miR-144 are potential circulating biomarkers of type 2 diabetes. In addition, miR-199a-3p and miR-223 are potential tissue biomarkers of type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-199a "Diabetes Mellitus, Type 2" 25677225 "This meta-analysis confirms that 40 miRNAs are significantly dysregulated in type 2 diabetes. miR-29a, miR-34a, miR-375,miR-103, miR-107, miR-132, miR-142-3p and miR-144 are potential circulating biomarkers of type 2 diabetes. In addition, miR-199a-3p and miR-223 are potential tissue biomarkers of type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-223 "Diabetes Mellitus, Type 2" 25677225 "This meta-analysis confirms that 40 miRNAs are significantly dysregulated in type 2 diabetes. miR-29a, miR-34a, miR-375,miR-103, miR-107, miR-132, miR-142-3p and miR-144 are potential circulating biomarkers of type 2 diabetes. In addition, miR-199a-3p and miR-223 are potential tissue biomarkers of type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-29a "Diabetes Mellitus, Type 2" 25677225 "This meta-analysis confirms that 40 miRNAs are significantly dysregulated in type 2 diabetes. miR-29a, miR-34a, miR-375,miR-103, miR-107, miR-132, miR-142-3p and miR-144 are potential circulating biomarkers of type 2 diabetes. In addition, miR-199a-3p and miR-223 are potential tissue biomarkers of type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-30e "Diabetes Mellitus, Type 2" 25677225 "This meta-analysis confirms that 40 miRNAs are significantly dysregulated in type 2 diabetes. miR-29a, miR-34a, miR-375,miR-103, miR-107, miR-132, miR-142-3p and miR-144 are potential circulating biomarkers of type 2 diabetes. In addition, miR-199a-3p and miR-223 are potential tissue biomarkers of type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-34a "Diabetes Mellitus, Type 2" 25677225 "This meta-analysis confirms that 40 miRNAs are significantly dysregulated in type 2 diabetes. miR-29a, miR-34a, miR-375,miR-103, miR-107, miR-132, miR-142-3p and miR-144 are potential circulating biomarkers of type 2 diabetes. In addition, miR-199a-3p and miR-223 are potential tissue biomarkers of type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-375 "Diabetes Mellitus, Type 2" 25677225 "This meta-analysis confirms that 40 miRNAs are significantly dysregulated in type 2 diabetes. miR-29a, miR-34a, miR-375,miR-103, miR-107, miR-132, miR-142-3p and miR-144 are potential circulating biomarkers of type 2 diabetes. In addition, miR-199a-3p and miR-223 are potential tissue biomarkers of type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-92a "Diabetes Mellitus, Type 2" 25677225 "This meta-analysis confirms that 40 miRNAs are significantly dysregulated in type 2 diabetes. miR-29a, miR-34a, miR-375,miR-103, miR-107, miR-132, miR-142-3p and miR-144 are potential circulating biomarkers of type 2 diabetes. In addition, miR-199a-3p and miR-223 are potential tissue biomarkers of type 2 diabetes." circulation_biomarker_diagnosis_ns hsa-mir-1225 Focal Segmental Glomerulosclerosis 25682967 Patients with FSGS and minimal change disease (MCD) have a unique circulating and urinary miRNA profile. The diagnostic and prognostic potential of miRNAs in FSGS and minimal change disease (MCD) warrants further studies. circulation_biomarker_diagnosis_ns hsa-mir-1915 Focal Segmental Glomerulosclerosis 25682967 Patients with FSGS and minimal change disease (MCD) have a unique circulating and urinary miRNA profile. The diagnostic and prognostic potential of miRNAs in FSGS and minimal change disease (MCD) warrants further studies. circulation_biomarker_diagnosis_ns hsa-mir-30b Focal Segmental Glomerulosclerosis 25682967 Patients with FSGS and minimal change disease (MCD) have a unique circulating and urinary miRNA profile. The diagnostic and prognostic potential of miRNAs in FSGS and minimal change disease (MCD) warrants further studies. circulation_biomarker_diagnosis_ns hsa-mir-30c Focal Segmental Glomerulosclerosis 25682967 Patients with FSGS and minimal change disease (MCD) have a unique circulating and urinary miRNA profile. The diagnostic and prognostic potential of miRNAs in FSGS and minimal change disease (MCD) warrants further studies. circulation_biomarker_diagnosis_ns hsa-mir-342 Focal Segmental Glomerulosclerosis 25682967 Patients with FSGS and minimal change disease (MCD) have a unique circulating and urinary miRNA profile. The diagnostic and prognostic potential of miRNAs in FSGS and minimal change disease (MCD) warrants further studies. circulation_biomarker_diagnosis_ns hsa-mir-34b Focal Segmental Glomerulosclerosis 25682967 Patients with FSGS and minimal change disease (MCD) have a unique circulating and urinary miRNA profile. The diagnostic and prognostic potential of miRNAs in FSGS and minimal change disease (MCD) warrants further studies. circulation_biomarker_diagnosis_ns hsa-mir-34c Focal Segmental Glomerulosclerosis 25682967 Patients with FSGS and minimal change disease (MCD) have a unique circulating and urinary miRNA profile. The diagnostic and prognostic potential of miRNAs in FSGS and minimal change disease (MCD) warrants further studies. circulation_biomarker_diagnosis_ns hsa-mir-663 Focal Segmental Glomerulosclerosis 25682967 Patients with FSGS and minimal change disease (MCD) have a unique circulating and urinary miRNA profile. The diagnostic and prognostic potential of miRNAs in FSGS and minimal change disease (MCD) warrants further studies. circulation_biomarker_diagnosis_ns hsa-mir-21 Colorectal Carcinoma 25683351 The accuracy of circulating microRNA-21 in the diagnosis of colorectal cancer: a systematic review and meta-analysis. circulation_biomarker_diagnosis_ns hsa-mir-127 "Carcinoma, Cervical" 25701838 Plasma miR-127 and miR-218 Might Serve as Potential Biomarkers for Cervical Cancer. circulation_biomarker_diagnosis_ns hsa-mir-218 "Carcinoma, Cervical" 25701838 Plasma miR-127 and miR-218 Might Serve as Potential Biomarkers for Cervical Cancer. circulation_biomarker_diagnosis_ns hsa-mir-28 Unstable Angina 25704294 "Our findings suggest that circulating miR-28-5p, involved in LXR¦Á-ABCA1 pathway, may be a potential biomarker for diagnosis and prognosis of unstable angina." circulation_biomarker_diagnosis_ns hsa-mir-125a "Carcinoma, Biliary Tract" 25706130 Our results suggest that the assessment of these miRNA markers is clinically valuable to identify patients with pancreato-biliary cancers who could benefit from surgical intervention. circulation_biomarker_diagnosis_ns hsa-mir-4294 "Carcinoma, Biliary Tract" 25706130 Our results suggest that the assessment of these miRNA markers is clinically valuable to identify patients with pancreato-biliary cancers who could benefit from surgical intervention. circulation_biomarker_diagnosis_ns hsa-mir-4476 "Carcinoma, Biliary Tract" 25706130 Our results suggest that the assessment of these miRNA markers is clinically valuable to identify patients with pancreato-biliary cancers who could benefit from surgical intervention. circulation_biomarker_diagnosis_ns hsa-mir-4530 "Carcinoma, Biliary Tract" 25706130 Our results suggest that the assessment of these miRNA markers is clinically valuable to identify patients with pancreato-biliary cancers who could benefit from surgical intervention. circulation_biomarker_diagnosis_ns hsa-mir-6075 "Carcinoma, Biliary Tract" 25706130 Our results suggest that the assessment of these miRNA markers is clinically valuable to identify patients with pancreato-biliary cancers who could benefit from surgical intervention. circulation_biomarker_diagnosis_ns hsa-mir-6799 "Carcinoma, Biliary Tract" 25706130 Our results suggest that the assessment of these miRNA markers is clinically valuable to identify patients with pancreato-biliary cancers who could benefit from surgical intervention. circulation_biomarker_diagnosis_ns hsa-mir-6836 "Carcinoma, Biliary Tract" 25706130 Our results suggest that the assessment of these miRNA markers is clinically valuable to identify patients with pancreato-biliary cancers who could benefit from surgical intervention. circulation_biomarker_diagnosis_ns hsa-mir-6880 "Carcinoma, Biliary Tract" 25706130 Our results suggest that the assessment of these miRNA markers is clinically valuable to identify patients with pancreato-biliary cancers who could benefit from surgical intervention. circulation_biomarker_diagnosis_ns hsa-mir-21 Allergic Asthma 25707810 Serum MicroRNA-21 as a Biomarker for Allergic Inflammatory Disease in Children. circulation_biomarker_diagnosis_ns hsa-mir-145 Ovarian Neoplasms 25722112 Serum microRNA-145 as a novel biomarker in human ovarian cancer. circulation_biomarker_diagnosis_ns hsa-mir-100 Breast Neoplasms 25722304 These results point to using high levels of tRNA-derived small RNA fragments in combination with known miR signatures of tumors to distinguish tumor-derived EVs in circulation from EVs derived from other cell sources. Such biomarkers would be unique to the EVs where high abundances of tRNA fragments are amplified with respect to their cellular levels. circulation_biomarker_diagnosis_ns hsa-let-7d Hyperactivity Disorder 25724585 Circulating MicroRNA Let-7d in Attention-Deficit/Hyperactivity Disorder. circulation_biomarker_diagnosis_ns hsa-mir-92a Colorectal Carcinoma 25736690 All 3 miRNAs studied were positively inter-correlated. circulation_biomarker_diagnosis_ns hsa-mir-196a Chronic Hepatitis C 25738504 Circulating microRNA-196a as a candidate diagnostic biomarker for chronic hepatitis C. circulation_biomarker_diagnosis_ns hsa-mir-126 Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-130a Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-135b Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-142 Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-149 Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-188 Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-18a Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-18b Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-203 Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-205 Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-224 Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-27a Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-29a Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-301a Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-517c Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-518 Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-518e Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-519d Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-93 Preeclampsia 25738738 "the miRNAs identified in this study as being abnormally expressed in PE, may be useful as non-invasive diagnostic biomarkers. Co-regulated mRNAs and possible causal pathways involved in the pathogenesis of PE were also identified." circulation_biomarker_diagnosis_ns hsa-mir-146a Heart Failure 25739750 "This study has shown for the first time that various miRNA combinations are useful biomarkers for HF, and also in the differentiation of HFpEF from HFrEF. The utility of these biomarker combinations can be altered by inclusion of natriuretic peptide. MiRNA biomarkers may support diagnostic strategies in subpopulations of patients with HF." circulation_biomarker_diagnosis_ns hsa-mir-221 Heart Failure 25739750 "This study has shown for the first time that various miRNA combinations are useful biomarkers for HF, and also in the differentiation of HFpEF from HFrEF. The utility of these biomarker combinations can be altered by inclusion of natriuretic peptide. MiRNA biomarkers may support diagnostic strategies in subpopulations of patients with HF." circulation_biomarker_diagnosis_ns hsa-mir-30c Heart Failure 25739750 "This study has shown for the first time that various miRNA combinations are useful biomarkers for HF, and also in the differentiation of HFpEF from HFrEF. The utility of these biomarker combinations can be altered by inclusion of natriuretic peptide. MiRNA biomarkers may support diagnostic strategies in subpopulations of patients with HF." circulation_biomarker_diagnosis_ns hsa-mir-328 Heart Failure 25739750 "This study has shown for the first time that various miRNA combinations are useful biomarkers for HF, and also in the differentiation of HFpEF from HFrEF. The utility of these biomarker combinations can be altered by inclusion of natriuretic peptide. MiRNA biomarkers may support diagnostic strategies in subpopulations of patients with HF." circulation_biomarker_diagnosis_ns hsa-mir-375 Heart Failure 25739750 "This study has shown for the first time that various miRNA combinations are useful biomarkers for HF, and also in the differentiation of HFpEF from HFrEF. The utility of these biomarker combinations can be altered by inclusion of natriuretic peptide. MiRNA biomarkers may support diagnostic strategies in subpopulations of patients with HF." circulation_biomarker_diagnosis_ns hsa-mir-155 Male Infertility 25740880 Serum miR-155 as a potential biomarker of male fertility. circulation_biomarker_diagnosis_ns hsa-mir-100 Acute Coronary Syndrome 25744750 Plasma microRNA-100 as a biomarker of coronary plaque vulnerability ¨C a new generation of biomarker for developing acute coronary syndrome. circulation_biomarker_diagnosis_ns hsa-mir-93 Tuberculosis 25753045 Identification of miR-93 as a suitable miR for normalizing miRNA in plasma of tuberculosis patients. circulation_biomarker_diagnosis_ns hsa-mir-375 Prostate Neoplasms 25754273 The combined serum levels of miR-375 and urokinase plasminogen activator receptor are suggested as diagnostic and prognostic biomarkers in prostate cancer. circulation_biomarker_diagnosis_ns hsa-mir-125a "Carcinoma, Lung, Non-Small-Cell" 25755772 "These preliminary data suggest that serum miR-125a-5p, miR-145 and miR-146a may be useful noninvasive biomarkers for the clinical diagnosis of NSCLC." circulation_biomarker_diagnosis_ns hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 25755772 "These preliminary data suggest that serum miR-125a-5p, miR-145 and miR-146a may be useful noninvasive biomarkers for the clinical diagnosis of NSCLC." circulation_biomarker_diagnosis_ns hsa-mir-146a "Carcinoma, Lung, Non-Small-Cell" 25755772 "These preliminary data suggest that serum miR-125a-5p, miR-145 and miR-146a may be useful noninvasive biomarkers for the clinical diagnosis of NSCLC." circulation_biomarker_diagnosis_ns hsa-mir-210 Glioma 25756397 Serum miR-210 is a promising diagnostic and prognostic biomarker that can be detected in the peripheral blood of patients with glioma. circulation_biomarker_diagnosis_ns hsa-let-7b Heart Failure 25763857 "Measured microRNA profiles did not separate the samples according to the clinical features of the patients. However, several previously identified heart failure marker microRNAs were detected. The pericardial fluid microRNA profile appeared to be a result of an active and selective secretory process indicating that microRNAs may act as paracrine signalling factors by mediating the local crosstalk between cardiac cells." circulation_biomarker_diagnosis_ns hsa-mir-31 Lung Neoplasms 25765717 miRNA-31 may be a molecular marker for the diagnostic and prognostic evaluation of primary lung cancer. circulation_biomarker_diagnosis_ns hsa-mir-195 Osteosarcoma 25775010 "Our data suggest that altered levels of circulating miRNAs might have great potential to serve as novel, non-invasive biomarkers for osteosarcoma." circulation_biomarker_diagnosis_ns hsa-mir-199a Osteosarcoma 25775010 "Our data suggest that altered levels of circulating miRNAs might have great potential to serve as novel, non-invasive biomarkers for osteosarcoma." circulation_biomarker_diagnosis_ns hsa-mir-320a Osteosarcoma 25775010 "Our data suggest that altered levels of circulating miRNAs might have great potential to serve as novel, non-invasive biomarkers for osteosarcoma." circulation_biomarker_diagnosis_ns hsa-mir-374a Osteosarcoma 25775010 "Our data suggest that altered levels of circulating miRNAs might have great potential to serve as novel, non-invasive biomarkers for osteosarcoma." circulation_biomarker_diagnosis_ns hsa-mir-21 Neoplasms [unspecific] 25777797 "Finally, the protocol was applied to monitor miRNA-21 expression in epithelial to mesenchymal transition (EMT)-induced MCF-7 cells, an epithelial tumor cell line. CK expression was lost in these cells,whereas miRNA-21 was still expressed, suggesting that miRNA-21 might be a good marker for detecting CTCs with an EMT phenotype." circulation_biomarker_diagnosis_ns hsa-mir-1 Myocardial Ischemic-Reperfusion Injury 25791720 "A time-dependent change in miR-1/208a/499 levels occurred during open-heart surgery, and these were associated with levels of cTnI and CK-MB.These results reveal that miRNAs may be sensitive biomarkers for I/R injury during open-heart surgery." circulation_biomarker_diagnosis_ns hsa-mir-208a Myocardial Ischemic-Reperfusion Injury 25791720 "A time-dependent change in miR-1/208a/499 levels occurred during open-heart surgery, and these were associated with levels of cTnI and CK-MB.These results reveal that miRNAs may be sensitive biomarkers for I/R injury during open-heart surgery." circulation_biomarker_diagnosis_ns hsa-mir-21 Myocardial Ischemic-Reperfusion Injury 25791720 "A time-dependent change in miR-1/208a/499 levels occurred during open-heart surgery, and these were associated with levels of cTnI and CK-MB.These results reveal that miRNAs may be sensitive biomarkers for I/R injury during open-heart surgery." circulation_biomarker_diagnosis_ns hsa-mir-499 Myocardial Ischemic-Reperfusion Injury 25791720 "A time-dependent change in miR-1/208a/499 levels occurred during open-heart surgery, and these were associated with levels of cTnI and CK-MB.These results reveal that miRNAs may be sensitive biomarkers for I/R injury during open-heart surgery." circulation_biomarker_diagnosis_ns hsa-mir-423 Colorectal Carcinoma 25807655 The significance of detection of serum miR-423-5p and miR-484 for diagnosis of colorectal cancer. circulation_biomarker_diagnosis_ns hsa-mir-484 Colorectal Carcinoma 25807655 The significance of detection of serum miR-423-5p and miR-484 for diagnosis of colorectal cancer. circulation_biomarker_diagnosis_ns hsa-mir-223 Sepsis 25810564 "Recent reports on alterations in miR-223 serum levels during sepsis revealed contradictory results, preventing a potential use of this miRNA in clinical routine. We clearly show that miR-223 serum levels do not reflect the presence of sepsis neither in mouse models nor in a large cohort of ICU patients and do not indicate clinical outcome of critically ill patients. Thus miR-223 serum levels should not be used as a biomarker in this setting." circulation_biomarker_diagnosis_ns hsa-let-7a "Carcinoma, Hepatocellular, HBV-Related" 25814782 "These findings highlight the importance of validating reference genes before quantifying target miRNAs.Furthermore, our findings will improve studies that monitor hepatitis progression and will aid in the discovery of noninvasive biomarkers to diagnose early stage HCC." circulation_biomarker_diagnosis_ns hsa-mir-125a Liver Diseases [unspecific] 25815788 "Serum microRNA-125a-5p, a useful biomarker in liver diseases, correlates with disease progression." circulation_biomarker_diagnosis_ns hsa-mir-223 Pancreatic Neoplasms 25819175 "Plasma miR-223 might be a clinically useful biomarker for screening PCa, and predicting malignant potential of IPMN and the invasiveness of PCa." circulation_biomarker_diagnosis_ns hsa-let-7d Epilepsy 25825351 "Circulating miRNAs were differentially regulated in epilepsy patients as compared with controls. MiR-106b-5p may serve as a novel, noninvasive biomarker to improve the current diagnosis of epilepsy." circulation_biomarker_diagnosis_ns hsa-mir-106b Epilepsy 25825351 "Circulating miRNAs were differentially regulated in epilepsy patients as compared with controls. MiR-106b-5p may serve as a novel, noninvasive biomarker to improve the current diagnosis of epilepsy." circulation_biomarker_diagnosis_ns hsa-mir-130a Epilepsy 25825351 "Circulating miRNAs were differentially regulated in epilepsy patients as compared with controls. MiR-106b-5p may serve as a novel, noninvasive biomarker to improve the current diagnosis of epilepsy." circulation_biomarker_diagnosis_ns hsa-mir-146a Epilepsy 25825351 "Circulating miRNAs were differentially regulated in epilepsy patients as compared with controls. MiR-106b-5p may serve as a novel, noninvasive biomarker to improve the current diagnosis of epilepsy." circulation_biomarker_diagnosis_ns hsa-mir-15a Epilepsy 25825351 "Circulating miRNAs were differentially regulated in epilepsy patients as compared with controls. MiR-106b-5p may serve as a novel, noninvasive biomarker to improve the current diagnosis of epilepsy." circulation_biomarker_diagnosis_ns hsa-mir-194 Epilepsy 25825351 "Circulating miRNAs were differentially regulated in epilepsy patients as compared with controls. MiR-106b-5p may serve as a novel, noninvasive biomarker to improve the current diagnosis of epilepsy." circulation_biomarker_diagnosis_ns hsa-mir-155 "Cardiomyopathy, Dilated" 25840506 We identified specific miRNAs that are differentially regulated between children with DCM who need a transplant compared with children with DCM who recover. A unique biomarker signature of miRNAs that are specific to children with DCM who have the potential to recover would be valuable in risk stratification of this challenging patient population. circulation_biomarker_diagnosis_ns hsa-mir-636 "Cardiomyopathy, Dilated" 25840506 We identified specific miRNAs that are differentially regulated between children with DCM who need a transplant compared with children with DCM who recover. A unique biomarker signature of miRNAs that are specific to children with DCM who have the potential to recover would be valuable in risk stratification of this challenging patient population. circulation_biomarker_diagnosis_ns hsa-mir-639 "Cardiomyopathy, Dilated" 25840506 We identified specific miRNAs that are differentially regulated between children with DCM who need a transplant compared with children with DCM who recover. A unique biomarker signature of miRNAs that are specific to children with DCM who have the potential to recover would be valuable in risk stratification of this challenging patient population. circulation_biomarker_diagnosis_ns hsa-mir-646 "Cardiomyopathy, Dilated" 25840506 We identified specific miRNAs that are differentially regulated between children with DCM who need a transplant compared with children with DCM who recover. A unique biomarker signature of miRNAs that are specific to children with DCM who have the potential to recover would be valuable in risk stratification of this challenging patient population. circulation_biomarker_diagnosis_ns hsa-let-7 Neoplasms [unspecific] 25856466 "Let-7, mir-98 and mir-183 as biomarkers for cancer and schizophrenia [corrected]." circulation_biomarker_diagnosis_ns hsa-mir-125b "Squamous Cell Carcinoma, Oral" 25858373 "Due to the satisfactory diagnostic performance, plasma miR-125b can be used as a promising biomarker in OSCC." circulation_biomarker_diagnosis_ns hsa-let-7a "Carcinoma, Gallbladder" 25861754 "Our results suggest a possible pathological relationship between the differential expression of miRNA in peripheral blood and GBC, and these dysregulated miRNAs could be novel tumor biomarkers for early detection of GBC." circulation_biomarker_diagnosis_ns hsa-mir-143 "Carcinoma, Gallbladder" 25861754 "Our results suggest a possible pathological relationship between the differential expression of miRNA in peripheral blood and GBC, and these dysregulated miRNAs could be novel tumor biomarkers for early detection of GBC." circulation_biomarker_diagnosis_ns hsa-mir-187 "Carcinoma, Gallbladder" 25861754 "Our results suggest a possible pathological relationship between the differential expression of miRNA in peripheral blood and GBC, and these dysregulated miRNAs could be novel tumor biomarkers for early detection of GBC." circulation_biomarker_diagnosis_ns hsa-mir-202 "Carcinoma, Gallbladder" 25861754 "Our results suggest a possible pathological relationship between the differential expression of miRNA in peripheral blood and GBC, and these dysregulated miRNAs could be novel tumor biomarkers for early detection of GBC." circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Gallbladder" 25861754 "Our results suggest a possible pathological relationship between the differential expression of miRNA in peripheral blood and GBC, and these dysregulated miRNAs could be novel tumor biomarkers for early detection of GBC." circulation_biomarker_diagnosis_ns hsa-mir-335 "Carcinoma, Gallbladder" 25861754 "Our results suggest a possible pathological relationship between the differential expression of miRNA in peripheral blood and GBC, and these dysregulated miRNAs could be novel tumor biomarkers for early detection of GBC." circulation_biomarker_diagnosis_ns hsa-mir-146a Chronic Hepatitis C 25877355 Involvement of TLR2-MyD88 in abnormal expression of miR-146a in peripheral blood monocytes of patients with chronic hepatitis C. circulation_biomarker_diagnosis_ns hsa-mir-10b Huntington Disease 25889241 "These results demonstrate that miRNA expression in cortical BA9 provides insight into striatal involvement and support a role for these miRNAs,particularly miR-10b-5p, in HD pathogenicity. The miRNAs identified in our studies of postmortem brain tissue may be detectable in peripheral fluids and thus warrant consideration as accessible biomarkers for disease stage, rate of progression, and other important clinical characteristics of HD." circulation_biomarker_diagnosis_ns hsa-mir-106b "Carcinoma, Hepatocellular" 25894380 We found that plasma miR-106b has clinical value in the detection of HCC from healthy people and CLD patients. Further large-scale study may be needed to validate our findings. circulation_biomarker_diagnosis_ns hsa-mir-34b "Carcinoma, Colon" 25894979 Increased microRNA-34b and -34c predominantly expressed in stromal tissues is associated with poor prognosis in human colon cancer. circulation_biomarker_diagnosis_ns hsa-mir-34c "Carcinoma, Colon" 25894979 Increased microRNA-34b and -34c predominantly expressed in stromal tissues is associated with poor prognosis in human colon cancer. circulation_biomarker_diagnosis_ns hsa-mir-1275 Intrahepatic Cholangiocarcinoma 25903557 "The association of unique miRNA profiles with different ICC subtypes suggests the involvement of specific miRNAs during ICC tumor progression. In plasma, an eight-miRNA signature associated with ICC could form the foundation of an accessible (plasma-based) miRNA-based biomarker for the early detection of ICC." circulation_biomarker_diagnosis_ns hsa-mir-193a Intrahepatic Cholangiocarcinoma 25903557 "The association of unique miRNA profiles with different ICC subtypes suggests the involvement of specific miRNAs during ICC tumor progression. In plasma, an eight-miRNA signature associated with ICC could form the foundation of an accessible (plasma-based) miRNA-based biomarker for the early detection of ICC." circulation_biomarker_diagnosis_ns hsa-mir-199b Intrahepatic Cholangiocarcinoma 25903557 "The association of unique miRNA profiles with different ICC subtypes suggests the involvement of specific miRNAs during ICC tumor progression. In plasma, an eight-miRNA signature associated with ICC could form the foundation of an accessible (plasma-based) miRNA-based biomarker for the early detection of ICC." circulation_biomarker_diagnosis_ns hsa-mir-320a Intrahepatic Cholangiocarcinoma 25903557 "The association of unique miRNA profiles with different ICC subtypes suggests the involvement of specific miRNAs during ICC tumor progression. In plasma, an eight-miRNA signature associated with ICC could form the foundation of an accessible (plasma-based) miRNA-based biomarker for the early detection of ICC." circulation_biomarker_diagnosis_ns hsa-mir-483 Intrahepatic Cholangiocarcinoma 25903557 "The association of unique miRNA profiles with different ICC subtypes suggests the involvement of specific miRNAs during ICC tumor progression. In plasma, an eight-miRNA signature associated with ICC could form the foundation of an accessible (plasma-based) miRNA-based biomarker for the early detection of ICC." circulation_biomarker_diagnosis_ns hsa-mir-505 Intrahepatic Cholangiocarcinoma 25903557 "The association of unique miRNA profiles with different ICC subtypes suggests the involvement of specific miRNAs during ICC tumor progression. In plasma, an eight-miRNA signature associated with ICC could form the foundation of an accessible (plasma-based) miRNA-based biomarker for the early detection of ICC." circulation_biomarker_diagnosis_ns hsa-mir-874 Intrahepatic Cholangiocarcinoma 25903557 "The association of unique miRNA profiles with different ICC subtypes suggests the involvement of specific miRNAs during ICC tumor progression. In plasma, an eight-miRNA signature associated with ICC could form the foundation of an accessible (plasma-based) miRNA-based biomarker for the early detection of ICC." circulation_biomarker_diagnosis_ns hsa-mir-148 "Carcinoma, Lung, Non-Small-Cell" 25904302 The results of present study suggest that the expression levels of circulating miR-148/152 family may serve as biomarkers for NSCLC. circulation_biomarker_diagnosis_ns hsa-mir-152 "Carcinoma, Lung, Non-Small-Cell" 25904302 The results of present study suggest that the expression levels of circulating miR-148/152 family may serve as biomarkers for NSCLC. circulation_biomarker_diagnosis_ns hsa-mir-21 Neoplasms [unspecific] 25907045 "we selectively detected cancer cell-derived exosomal miRNA-21 among heterogeneous exosome mixtures and in human serum. The method developed in the article is simple, fast, and sensitive, so it will offer great opportunities for the high-throughput diagnosis and prognosis of diseases." circulation_biomarker_diagnosis_ns hsa-mir-221 "Carcinoma, Renal Cell" 25909813 Combined Influence of EGF+61G>A and TGFB+869T>C Functional Polymorphisms in Renal Cell Carcinoma Progression and Overall Survival: The Link to Plasma Circulating MiR-7 and MiR-221/222 Expression. circulation_biomarker_diagnosis_ns hsa-mir-222 "Carcinoma, Renal Cell" 25909813 Combined Influence of EGF+61G>A and TGFB+869T>C Functional Polymorphisms in Renal Cell Carcinoma Progression and Overall Survival: The Link to Plasma Circulating MiR-7 and MiR-221/222 Expression. circulation_biomarker_diagnosis_ns hsa-mir-7 "Carcinoma, Renal Cell" 25909813 Combined Influence of EGF+61G>A and TGFB+869T>C Functional Polymorphisms in Renal Cell Carcinoma Progression and Overall Survival: The Link to Plasma Circulating MiR-7 and MiR-221/222 Expression. circulation_biomarker_diagnosis_ns hsa-let-7a "Squamous Cell Carcinoma, Esophageal" 25914476 Plasma miR-20a and let-7a levels are significantly altered in patients with ESCC and can be used as potential biomarkers in the diagnosis of ESCC. circulation_biomarker_diagnosis_ns hsa-mir-20a "Squamous Cell Carcinoma, Esophageal" 25914476 Plasma miR-20a and let-7a levels are significantly altered in patients with ESCC and can be used as potential biomarkers in the diagnosis of ESCC. circulation_biomarker_diagnosis_ns hsa-mir-122 Acute Coronary Syndrome 25933289 "Plasma miR-122, -140-3p, -720, -2861, and -3149 were associated with and potentially novel biomarkers for ACS." circulation_biomarker_diagnosis_ns hsa-mir-3149 Acute Coronary Syndrome 25933289 "Plasma miR-122, -140-3p, -720, -2861, and -3149 were associated with and potentially novel biomarkers for ACS." circulation_biomarker_diagnosis_ns hsa-mir-572 Multiple Sclerosis 25947625 Evaluation of miR-572 may serve as a non-invasive biomarker for remyelination. circulation_biomarker_diagnosis_ns hsa-mir-126 Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-142 Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-146b Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-150 Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-155 Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-15b Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-191 Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-193a Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-29b Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-30c Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-32 Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-34a Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-744 Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-886 Brain Disease [unspecific] 25947950 MiRNAs are detectable in cerebral microdialysate; a large group of miRNAs consistently showed a high RR in cerebral microdialysate. Measurement of cerebral interstitial miRNA concentrations may aid in the investigation of secondary brain injury in neurocritical conditions. circulation_biomarker_diagnosis_ns hsa-mir-146a Uveal Melanoma 25951497 "Our findings suggest the possibility to detect in VH and serum of UM patients diagnostic miRNAs released by the affected eye: based on this,miR-146a could be considered a potential circulating marker of UM." circulation_biomarker_diagnosis_ns hsa-mir-21 Uveal Melanoma 25951497 "Our findings suggest the possibility to detect in VH and serum of UM patients diagnostic miRNAs released by the affected eye: based on this,miR-146a could be considered a potential circulating marker of UM." circulation_biomarker_diagnosis_ns hsa-mir-34a Uveal Melanoma 25951497 "Our findings suggest the possibility to detect in VH and serum of UM patients diagnostic miRNAs released by the affected eye: based on this,miR-146a could be considered a potential circulating marker of UM." circulation_biomarker_diagnosis_ns hsa-mir-130b Diabetic Nephropathy 25952368 "Our findings suggest that serum miR-130b may be a new biomarker for the early diagnosis of DN in T2DM. Circulating miR-130b may possibly be involved in the pathological mechanism of DN, such as lipid metabolic disorders, oxidative stress, extracellular matrix deposition and renal fibrosis." circulation_biomarker_diagnosis_ns hsa-mir-27a Osteosarcoma 25960240 miR-27a expression may be elevated in sera of osteosarcoma patients and in turn contributes to aggressive progression of this malignancy. Detection of serum miR-27a levels may have clinical potentials as a non-invasive diagnostic/prognostic biomarker for osteosarcoma patients. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Hepatocellular" 25973032 Significance of serum microRNA-21 in diagnosis of hepatocellular carcinoma (HCC):clinical analyses of patients and an HCC rat model. circulation_biomarker_diagnosis_ns hsa-mir-194 Myelodysplastic Syndromes 25975751 MicroRNA-194-5p could serve as a diagnostic and prognostic biomarker in myelodysplastic syndromes. circulation_biomarker_diagnosis_ns hsa-mir-181b Hepatitis B Virus Infection 25976622 Serum miR-181b is correlated with liver and serum HBV DNA levels as well as disease progression in CHB. circulation_biomarker_diagnosis_ns hsa-mir-155 Preeclampsia 25981845 "The systemic effect of PE on maternal systems is evident in the circulating miRNAome with substantial alterations in miRNA expression in women who develop severe PE. In addition we provide novel evidence of disruption to miR-221 expression 1 year postpartum following a pregnancy complicated by PE compared to normotensive time-matched controls, which may allude to persistent inflammation in these women after delivery." circulation_biomarker_diagnosis_ns hsa-mir-210 Preeclampsia 25981845 "The systemic effect of PE on maternal systems is evident in the circulating miRNAome with substantial alterations in miRNA expression in women who develop severe PE. In addition we provide novel evidence of disruption to miR-221 expression 1 year postpartum following a pregnancy complicated by PE compared to normotensive time-matched controls, which may allude to persistent inflammation in these women after delivery." circulation_biomarker_diagnosis_ns hsa-mir-222 Preeclampsia 25981845 "The systemic effect of PE on maternal systems is evident in the circulating miRNAome with substantial alterations in miRNA expression in women who develop severe PE. In addition we provide novel evidence of disruption to miR-221 expression 1 year postpartum following a pregnancy complicated by PE compared to normotensive time-matched controls, which may allude to persistent inflammation in these women after delivery." circulation_biomarker_diagnosis_ns hsa-mir-296 Preeclampsia 25981845 "The systemic effect of PE on maternal systems is evident in the circulating miRNAome with substantial alterations in miRNA expression in women who develop severe PE. In addition we provide novel evidence of disruption to miR-221 expression 1 year postpartum following a pregnancy complicated by PE compared to normotensive time-matched controls, which may allude to persistent inflammation in these women after delivery." circulation_biomarker_diagnosis_ns hsa-mir-29b Preeclampsia 25981845 "The systemic effect of PE on maternal systems is evident in the circulating miRNAome with substantial alterations in miRNA expression in women who develop severe PE. In addition we provide novel evidence of disruption to miR-221 expression 1 year postpartum following a pregnancy complicated by PE compared to normotensive time-matched controls, which may allude to persistent inflammation in these women after delivery." circulation_biomarker_diagnosis_ns hsa-mir-98 Preeclampsia 25981845 "The systemic effect of PE on maternal systems is evident in the circulating miRNAome with substantial alterations in miRNA expression in women who develop severe PE. In addition we provide novel evidence of disruption to miR-221 expression 1 year postpartum following a pregnancy complicated by PE compared to normotensive time-matched controls, which may allude to persistent inflammation in these women after delivery." circulation_biomarker_diagnosis_ns hsa-mir-520h Breast Neoplasms 25982274 miR-520h is crucial for DAPK2 regulation and breast cancer progression. circulation_biomarker_diagnosis_ns hsa-mir-19 Crohn Disease 25985247 These data identify miR-19-3p as a potential circulating marker of stricturing CD. Our data show that microRNAs have utility as noninvasive biomarkers of stricturing CD. Further longitudinal studies are required to determine the prognostic value of miR-19-3p at diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-182 Heart Failure 25985726 "miR-182 (p = 0.04), miR-200a* (p = 0.019), and miR-568 (p = 0.023) were found to be inversely correlated with LVM index (LVMI), while miR-155 (p = 0.019) and miR-595 (p = 0.04) were determined to be positively correlated with LVMI." circulation_biomarker_diagnosis_ns hsa-mir-132 Schizophrenia 25985888 Alterations of miR-132 are novel diagnostic biomarkers in peripheral blood of schizophrenia patients. circulation_biomarker_diagnosis_ns hsa-mir-18b Rectal Neoplasms 25990502 MicroRNA expression in patient plasma changes during preoperative CRT. The alteration is not continuous and the meaning requires additional analysis on a larger patient cohort. The co-occurrence of reduced miR-18b and miR-20a expression with lymph node negativity after preoperative CRT could help to stratify the surgical procedure with respect to total mesorectal excision and LR if validated prospectively. circulation_biomarker_diagnosis_ns hsa-mir-20a Rectal Neoplasms 25990502 MicroRNA expression in patient plasma changes during preoperative CRT. The alteration is not continuous and the meaning requires additional analysis on a larger patient cohort. The co-occurrence of reduced miR-18b and miR-20a expression with lymph node negativity after preoperative CRT could help to stratify the surgical procedure with respect to total mesorectal excision and LR if validated prospectively. circulation_biomarker_diagnosis_ns hsa-mir-30d Heart Failure 25995320 Baseline plasma miR-30d level is associated with response to CRT in HFDYS in this translational pilot study. MiR-30d increase in cardiomyocytes correlates with areas of increased wall stress in HFDYS and is protective against deleterious tumor necrosis factor signaling. circulation_biomarker_diagnosis_ns hsa-mir-183 Human Immunodeficiency Virus Infection 25997625 "We show for the first time a joint miRNA and mRNA expression profile related to a HIV-1 latency phenotype, outline a dynamic network of potential regulators involving in HIV-1 latency or replication state, and gain new insights into the source messages for affecting HIV-1 latency." circulation_biomarker_diagnosis_ns hsa-mir-125 Polycythemia Vera 26011312 "In conclusion, our data indicate that other factors such as aberrant miR-125 expression may influence on the disease phenotype in patients with PV and ET." circulation_biomarker_diagnosis_ns hsa-mir-497 Bladder Neoplasms 26014226 Circulating miR-497 and miR-663b in plasma are potential novel biomarkers for bladder cancer. circulation_biomarker_diagnosis_ns hsa-mir-663a Bladder Neoplasms 26014226 Circulating miR-497 and miR-663b in plasma are potential novel biomarkers for bladder cancer. circulation_biomarker_diagnosis_ns hsa-mir-142 Vasculitis 26016752 "In this first study ever on circulating miRNA profiles in AAV, we find clear indication of their potential as biomarkers for diagnosis and classification, but more studies are needed to identify the best markers as well as the mechanisms responsible for variations." circulation_biomarker_diagnosis_ns hsa-mir-20a Vasculitis 26016752 "In this first study ever on circulating miRNA profiles in AAV, we find clear indication of their potential as biomarkers for diagnosis and classification, but more studies are needed to identify the best markers as well as the mechanisms responsible for variations." circulation_biomarker_diagnosis_ns hsa-mir-221 Vasculitis 26016752 "In this first study ever on circulating miRNA profiles in AAV, we find clear indication of their potential as biomarkers for diagnosis and classification, but more studies are needed to identify the best markers as well as the mechanisms responsible for variations." circulation_biomarker_diagnosis_ns hsa-mir-29a Vasculitis 26016752 "In this first study ever on circulating miRNA profiles in AAV, we find clear indication of their potential as biomarkers for diagnosis and classification, but more studies are needed to identify the best markers as well as the mechanisms responsible for variations." circulation_biomarker_diagnosis_ns hsa-mir-34a Vasculitis 26016752 "In this first study ever on circulating miRNA profiles in AAV, we find clear indication of their potential as biomarkers for diagnosis and classification, but more studies are needed to identify the best markers as well as the mechanisms responsible for variations." circulation_biomarker_diagnosis_ns hsa-mir-383 Vasculitis 26016752 "In this first study ever on circulating miRNA profiles in AAV, we find clear indication of their potential as biomarkers for diagnosis and classification, but more studies are needed to identify the best markers as well as the mechanisms responsible for variations." circulation_biomarker_diagnosis_ns hsa-mir-92a Vasculitis 26016752 "In this first study ever on circulating miRNA profiles in AAV, we find clear indication of their potential as biomarkers for diagnosis and classification, but more studies are needed to identify the best markers as well as the mechanisms responsible for variations." circulation_biomarker_diagnosis_ns hsa-mir-24 "Carcinoma, Nasopharyngeal" 26018275 Plasma miR-24 may serve as a novel molecular biomarker for early diagnosis and prognosis of NPC. circulation_biomarker_diagnosis_ns hsa-let-7g Osteoporosis 26026730 "In total 6 miRNAs, miR-10a-5p, miR-10b-5p, miR-133b, miR-22-3p, miR-328-3p, and let-7g-5p exhibited significantly different serum levels in response to fracture" circulation_biomarker_diagnosis_ns hsa-mir-107 Breast Neoplasms 26033453 "Aberrant plasma levels of circulating miR-16, miR-107, miR-130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients." circulation_biomarker_diagnosis_ns hsa-mir-130a Breast Neoplasms 26033453 "Aberrant plasma levels of circulating miR-16, miR-107, miR-130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients." circulation_biomarker_diagnosis_ns hsa-mir-146a Breast Neoplasms 26033453 "Aberrant plasma levels of circulating miR-16, miR-107, miR-130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients." circulation_biomarker_diagnosis_ns hsa-mir-16 Breast Neoplasms 26033453 "Aberrant plasma levels of circulating miR-16, miR-107, miR-130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients." circulation_biomarker_diagnosis_ns hsa-mir-200c Neoplasms [unspecific] 26035744 "in clinicopathology analysis,miR-200c expression in blood was significantly associated with TNM stage, lymph node metastasis and distant metastasis. MiR-200c may have the potential to become a new blood biomarker to monitor cancer prognosis and progression." circulation_biomarker_diagnosis_ns hsa-mir-125b Colorectal Carcinoma 26038573 "Because serum levels of miR-21, miR-29a, and miR-125b discriminated patients with early colorectal neoplasm from healthy controls, our data highlight the potential clinical use of these molecular signatures for noninvasive screening of patients with colorectal neoplasia." circulation_biomarker_diagnosis_ns hsa-mir-21 Colorectal Carcinoma 26038573 "Because serum levels of miR-21, miR-29a, and miR-125b discriminated patients with early colorectal neoplasm from healthy controls, our data highlight the potential clinical use of these molecular signatures for noninvasive screening of patients with colorectal neoplasia." circulation_biomarker_diagnosis_ns hsa-mir-29a Colorectal Carcinoma 26038573 "Because serum levels of miR-21, miR-29a, and miR-125b discriminated patients with early colorectal neoplasm from healthy controls, our data highlight the potential clinical use of these molecular signatures for noninvasive screening of patients with colorectal neoplasia." circulation_biomarker_diagnosis_ns hsa-mir-1246 Melanoma 26039581 A profile of 2 miRNAs (miR-1246 and miR-185) significantly associated with metastatic melanoma with a sensitivity of 90.5% and a specificity of 89.1% was identified. This plasma miRNA profile may become an accurate non-invasive biomarker for melanoma. circulation_biomarker_diagnosis_ns hsa-mir-185 Melanoma 26039581 A profile of 2 miRNAs (miR-1246 and miR-185) significantly associated with metastatic melanoma with a sensitivity of 90.5% and a specificity of 89.1% was identified. This plasma miRNA profile may become an accurate non-invasive biomarker for melanoma. circulation_biomarker_diagnosis_ns hsa-mir-206 Melanoma 26045823 "Our results offer the convincing evidence that miR-206 may be implicated in aggressive progression of melanoma. More importantly, the serum level of miR-206 may be a noninvasive prognostic biomarker for the patients with melanoma." circulation_biomarker_diagnosis_ns hsa-mir-586 Graft-Versus-Host Disease 26051902 Plasma microRNA-586 is a new biomarker for acute graft-versus-host disease. circulation_biomarker_diagnosis_ns hsa-mir-101 Mycobacterium tuberculosis Infection 26053546 A unique signature of 11 microRNAs in human macrophages was identified to differentiate active MTB disease from LTBI and healthy controls. circulation_biomarker_diagnosis_ns hsa-mir-140 Mycobacterium tuberculosis Infection 26053546 A unique signature of 11 microRNAs in human macrophages was identified to differentiate active MTB disease from LTBI and healthy controls. circulation_biomarker_diagnosis_ns hsa-mir-146b Mycobacterium tuberculosis Infection 26053546 A unique signature of 11 microRNAs in human macrophages was identified to differentiate active MTB disease from LTBI and healthy controls. circulation_biomarker_diagnosis_ns hsa-mir-150 Mycobacterium tuberculosis Infection 26053546 A unique signature of 11 microRNAs in human macrophages was identified to differentiate active MTB disease from LTBI and healthy controls. circulation_biomarker_diagnosis_ns hsa-mir-193a Mycobacterium tuberculosis Infection 26053546 A unique signature of 11 microRNAs in human macrophages was identified to differentiate active MTB disease from LTBI and healthy controls. circulation_biomarker_diagnosis_ns hsa-mir-21 Mycobacterium tuberculosis Infection 26053546 A unique signature of 11 microRNAs in human macrophages was identified to differentiate active MTB disease from LTBI and healthy controls. circulation_biomarker_diagnosis_ns hsa-mir-296 Mycobacterium tuberculosis Infection 26053546 A unique signature of 11 microRNAs in human macrophages was identified to differentiate active MTB disease from LTBI and healthy controls. circulation_biomarker_diagnosis_ns hsa-mir-485 Mycobacterium tuberculosis Infection 26053546 A unique signature of 11 microRNAs in human macrophages was identified to differentiate active MTB disease from LTBI and healthy controls. circulation_biomarker_diagnosis_ns hsa-mir-125b Breast Neoplasms 26056355 Circulating miRNAs reflect the presence of breast tumors. The identification of deregulated miRNAs in plasma of patients with breast cancer supports the use of circulating miRNAs as a method for early breast cancer detection. circulation_biomarker_diagnosis_ns hsa-mir-21 Breast Neoplasms 26056355 Circulating miRNAs reflect the presence of breast tumors. The identification of deregulated miRNAs in plasma of patients with breast cancer supports the use of circulating miRNAs as a method for early breast cancer detection. circulation_biomarker_diagnosis_ns hsa-mir-505 Breast Neoplasms 26056355 Circulating miRNAs reflect the presence of breast tumors. The identification of deregulated miRNAs in plasma of patients with breast cancer supports the use of circulating miRNAs as a method for early breast cancer detection. circulation_biomarker_diagnosis_ns hsa-mir-96 Breast Neoplasms 26056355 Circulating miRNAs reflect the presence of breast tumors. The identification of deregulated miRNAs in plasma of patients with breast cancer supports the use of circulating miRNAs as a method for early breast cancer detection. circulation_biomarker_diagnosis_ns hsa-mir-185 Gastric Neoplasms 26059512 "In conclusion, we identified a five-miRNA signature in the peripheral plasma which could serve as a non-invasive biomarker in detection of GC." circulation_biomarker_diagnosis_ns hsa-mir-20a Gastric Neoplasms 26059512 "In conclusion, we identified a five-miRNA signature in the peripheral plasma which could serve as a non-invasive biomarker in detection of GC." circulation_biomarker_diagnosis_ns hsa-mir-210 Gastric Neoplasms 26059512 "In conclusion, we identified a five-miRNA signature in the peripheral plasma which could serve as a non-invasive biomarker in detection of GC." circulation_biomarker_diagnosis_ns hsa-mir-92b Gastric Neoplasms 26059512 "In conclusion, we identified a five-miRNA signature in the peripheral plasma which could serve as a non-invasive biomarker in detection of GC." circulation_biomarker_diagnosis_ns hsa-mir-103a Autism Spectrum Disorder 26061495 "this study provides the first global miRNA expression profile of ASD in China. The differentially expressed miR-34b may potentially explain the higher percentage of male ASD patients, and the aberrantly expressed miR-103a-3p may contribute to the abnormal ubiquitin-mediated proteolysis observed in ASD." circulation_biomarker_diagnosis_ns hsa-mir-34b Autism Spectrum Disorder 26061495 "this study provides the first global miRNA expression profile of ASD in China. The differentially expressed miR-34b may potentially explain the higher percentage of male ASD patients, and the aberrantly expressed miR-103a-3p may contribute to the abnormal ubiquitin-mediated proteolysis observed in ASD." circulation_biomarker_diagnosis_ns hsa-mir-21 Breast Neoplasms 26063582 "In conclusion, our findings demonstrate that serum miR-21 expression profile may serve as a potential non-invasive diagnostic and prognostic biomarker for breast cancer." circulation_biomarker_diagnosis_ns hsa-mir-1246 "Leukemia, Myeloid, Acute" 26067326 "We propose development of serum exosome miRNA as a platform for a novel,sensitive compartment biomarker for prospective tracking and early detection of AML recurrence." circulation_biomarker_diagnosis_ns hsa-mir-155 "Leukemia, Myeloid, Acute" 26067326 "We propose development of serum exosome miRNA as a platform for a novel,sensitive compartment biomarker for prospective tracking and early detection of AML recurrence." circulation_biomarker_diagnosis_ns hsa-mir-199a Osteosarcoma 26069101 Identification of miR-199a-5p in serum as noninvasive biomarkers for detecting and monitoring osteosarcoma. circulation_biomarker_diagnosis_ns hsa-mir-3662 Lung Neoplasms 26079400 Plasma circulating microRNA-944 and microRNA-3662 as potential histologic type-specific early lung cancer biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-944 Lung Neoplasms 26079400 Plasma circulating microRNA-944 and microRNA-3662 as potential histologic type-specific early lung cancer biomarkers. circulation_biomarker_diagnosis_ns hsa-let-7a Liver Neoplasms 26082194 Assessment of endogenous reference gene suitability for serum exosomal microRNA expression analysis in liver carcinoma resection studies. circulation_biomarker_diagnosis_ns hsa-mir-103 Liver Neoplasms 26082194 Assessment of endogenous reference gene suitability for serum exosomal microRNA expression analysis in liver carcinoma resection studies. circulation_biomarker_diagnosis_ns hsa-mir-16 Liver Neoplasms 26082194 Assessment of endogenous reference gene suitability for serum exosomal microRNA expression analysis in liver carcinoma resection studies. circulation_biomarker_diagnosis_ns hsa-mir-191 Liver Neoplasms 26082194 Assessment of endogenous reference gene suitability for serum exosomal microRNA expression analysis in liver carcinoma resection studies. circulation_biomarker_diagnosis_ns hsa-mir-221 Liver Neoplasms 26082194 Assessment of endogenous reference gene suitability for serum exosomal microRNA expression analysis in liver carcinoma resection studies. circulation_biomarker_diagnosis_ns hsa-mir-26a Liver Neoplasms 26082194 Assessment of endogenous reference gene suitability for serum exosomal microRNA expression analysis in liver carcinoma resection studies. circulation_biomarker_diagnosis_ns hsa-mir-451 Liver Neoplasms 26082194 Assessment of endogenous reference gene suitability for serum exosomal microRNA expression analysis in liver carcinoma resection studies. circulation_biomarker_diagnosis_ns hsa-mir-34c "Diabetes Mellitus, Type 2" 26083362 "The expression profile of microRNAs/mRNAs in monocytes of T2D patients indicates an altered adhesion, differentiation, and shape change potential. Monocyte inflammatory activation was only found in patients with normal serum lipids. Abnormal lipid values coincided with a reduced monocyte inflammatory state." circulation_biomarker_diagnosis_ns hsa-mir-133a "Cardiomyopathy, Hypertrophic" 26086795 "We demonstrated that miR-29a and miR-29c show a specific signature to distinguish between aortic stenosis, hypertrophic non-obstructive and obstructive cardiomyopathies and thus could be developed into clinically useful biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-143 "Cardiomyopathy, Hypertrophic" 26086795 "We demonstrated that miR-29a and miR-29c show a specific signature to distinguish between aortic stenosis, hypertrophic non-obstructive and obstructive cardiomyopathies and thus could be developed into clinically useful biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-145 "Cardiomyopathy, Hypertrophic" 26086795 "We demonstrated that miR-29a and miR-29c show a specific signature to distinguish between aortic stenosis, hypertrophic non-obstructive and obstructive cardiomyopathies and thus could be developed into clinically useful biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-192 "Cardiomyopathy, Hypertrophic" 26086795 "We demonstrated that miR-29a and miR-29c show a specific signature to distinguish between aortic stenosis, hypertrophic non-obstructive and obstructive cardiomyopathies and thus could be developed into clinically useful biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-29a "Cardiomyopathy, Hypertrophic" 26086795 "We demonstrated that miR-29a and miR-29c show a specific signature to distinguish between aortic stenosis, hypertrophic non-obstructive and obstructive cardiomyopathies and thus could be developed into clinically useful biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-29c "Cardiomyopathy, Hypertrophic" 26086795 "We demonstrated that miR-29a and miR-29c show a specific signature to distinguish between aortic stenosis, hypertrophic non-obstructive and obstructive cardiomyopathies and thus could be developed into clinically useful biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-505 "Cardiomyopathy, Hypertrophic" 26086795 "We demonstrated that miR-29a and miR-29c show a specific signature to distinguish between aortic stenosis, hypertrophic non-obstructive and obstructive cardiomyopathies and thus could be developed into clinically useful biomarkers." circulation_biomarker_diagnosis_ns hsa-mir-26a Cholangiocarcinoma 26087181 Serum miR-26a as a diagnostic and prognostic biomarker in cholangiocarcinoma. circulation_biomarker_diagnosis_ns hsa-mir-143 "Carcinoma, Hepatocellular" 26088272 "A serum microRNA classifier for early detection of hepatocellular carcinoma: a multicentre, retrospective, longitudinal biomarker identification study with a nested case-control study." circulation_biomarker_diagnosis_ns hsa-mir-145 "Carcinoma, Hepatocellular" 26088272 "A serum microRNA classifier for early detection of hepatocellular carcinoma: a multicentre, retrospective, longitudinal biomarker identification study with a nested case-control study." circulation_biomarker_diagnosis_ns hsa-mir-192 "Carcinoma, Hepatocellular" 26088272 "A serum microRNA classifier for early detection of hepatocellular carcinoma: a multicentre, retrospective, longitudinal biomarker identification study with a nested case-control study." circulation_biomarker_diagnosis_ns hsa-mir-29a "Carcinoma, Hepatocellular" 26088272 "A serum microRNA classifier for early detection of hepatocellular carcinoma: a multicentre, retrospective, longitudinal biomarker identification study with a nested case-control study." circulation_biomarker_diagnosis_ns hsa-mir-29c "Carcinoma, Hepatocellular" 26088272 "A serum microRNA classifier for early detection of hepatocellular carcinoma: a multicentre, retrospective, longitudinal biomarker identification study with a nested case-control study." circulation_biomarker_diagnosis_ns hsa-mir-505 "Carcinoma, Hepatocellular" 26088272 "A serum microRNA classifier for early detection of hepatocellular carcinoma: a multicentre, retrospective, longitudinal biomarker identification study with a nested case-control study." circulation_biomarker_diagnosis_ns hsa-mir-126a Acute Pancreatitis 26094040 Serum levels of unique miR-551-5p and endothelial-specific miR-126a-5p allow discrimination of patients in the early phase of acute pancreatitis. circulation_biomarker_diagnosis_ns hsa-mir-551 Acute Pancreatitis 26094040 Serum levels of unique miR-551-5p and endothelial-specific miR-126a-6p allow discrimination of patients in the early phase of acute pancreatitis. circulation_biomarker_diagnosis_ns hsa-mir-520d Neoplasms [unspecific] 26094174 "Among HKGs that were expressed in all samples, we suggest that RNU6 and miR-520d-5p were the best candidates for HKGs for studies of plasma miRNA because of the consistent and high Ct in all samples and a very narrow,reproducible SD." circulation_biomarker_diagnosis_ns hsa-mir-145 Acute Ischemic Stroke 26096228 Circulating miR-145 is associated with plasma high-sensitivity C-reactive protein in acute ischemic stroke patients. circulation_biomarker_diagnosis_ns hsa-mir-145 Acute Kidney Failure 26106607 "miR-200a/b/c, miR-145, miR-192, miR-194, miR-216a/b, miR-217, and miR-449a expression profiles are useful as biomarkers for identification of various kidney injuries." circulation_biomarker_diagnosis_ns hsa-mir-192 Acute Kidney Failure 26106607 "miR-200a/b/c, miR-145, miR-192, miR-194, miR-216a/b, miR-217, and miR-449a expression profiles are useful as biomarkers for identification of various kidney injuries." circulation_biomarker_diagnosis_ns hsa-mir-194 Acute Kidney Failure 26106607 "miR-200a/b/c, miR-145, miR-192, miR-194, miR-216a/b, miR-217, and miR-449a expression profiles are useful as biomarkers for identification of various kidney injuries." circulation_biomarker_diagnosis_ns hsa-mir-200a Acute Kidney Failure 26106607 "miR-200a/b/c, miR-145, miR-192, miR-194, miR-216a/b, miR-217, and miR-449a expression profiles are useful as biomarkers for identification of various kidney injuries." circulation_biomarker_diagnosis_ns hsa-mir-200b Acute Kidney Failure 26106607 "miR-200a/b/c, miR-145, miR-192, miR-194, miR-216a/b, miR-217, and miR-449a expression profiles are useful as biomarkers for identification of various kidney injuries." circulation_biomarker_diagnosis_ns hsa-mir-200c Acute Kidney Failure 26106607 "miR-200a/b/c, miR-145, miR-192, miR-194, miR-216a/b, miR-217, and miR-449a expression profiles are useful as biomarkers for identification of various kidney injuries." circulation_biomarker_diagnosis_ns hsa-mir-216a Acute Kidney Failure 26106607 "miR-200a/b/c, miR-145, miR-192, miR-194, miR-216a/b, miR-217, and miR-449a expression profiles are useful as biomarkers for identification of various kidney injuries." circulation_biomarker_diagnosis_ns hsa-mir-216b Acute Kidney Failure 26106607 "miR-200a/b/c, miR-145, miR-192, miR-194, miR-216a/b, miR-217, and miR-449a expression profiles are useful as biomarkers for identification of various kidney injuries." circulation_biomarker_diagnosis_ns hsa-mir-217 Acute Kidney Failure 26106607 "miR-200a/b/c, miR-145, miR-192, miR-194, miR-216a/b, miR-217, and miR-449a expression profiles are useful as biomarkers for identification of various kidney injuries." circulation_biomarker_diagnosis_ns hsa-mir-449a Acute Kidney Failure 26106607 "miR-200a/b/c, miR-145, miR-192, miR-194, miR-216a/b, miR-217, and miR-449a expression profiles are useful as biomarkers for identification of various kidney injuries." circulation_biomarker_diagnosis_ns hsa-mir-21 Lung Neoplasms 26109362 "MiR-21 expression levels in whole blood and peripheral blood cells did not show significant differences between lung cancer patients and healthy controls, and it might be ineffective to measure miR-21 expression to achieve an early diagnosis of lung cancer." circulation_biomarker_diagnosis_ns hsa-mir-21 Hypertension 26114349 "The decreased levels of NOx and eNOS found in this study indicate the co-existence of endothelial dysfunction and hypertension once more. In the absence of microalbuminuria, the increased miR-21 expression in patients with iCIMT made us conclude that this miRNA might be involved in the early stages of atherosclerotic process in hypertensive patients." circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Hepatocellular" 26114756 Our current findings suggested that circulating miR-21 can serve as a potential co-biomarker for early-stage HCC diagnosis. Thorough large-scale studies are needed to confirm the generalizability of our findings. circulation_biomarker_diagnosis_ns hsa-mir-15b "Carcinoma, Hepatocellular" 26119771 "Circulating miR-15b-5p, miR-338-5p, and miR-764 may be biomarkers for diagnosis of HCC." circulation_biomarker_diagnosis_ns hsa-mir-338 "Carcinoma, Hepatocellular" 26119771 "Circulating miR-15b-5p, miR-338-5p, and miR-764 may be biomarkers for diagnosis of HCC." circulation_biomarker_diagnosis_ns hsa-mir-764 "Carcinoma, Hepatocellular" 26119771 "Circulating miR-15b-5p, miR-338-5p, and miR-764 may be biomarkers for diagnosis of HCC." circulation_biomarker_diagnosis_ns hsa-mir-144 Breast Neoplasms 26124344 Differentially expressed miRNAs from PBMCs may be potential non-invasive biomarkers for breast cancer prediction. Larger prospective studies are required to confirm whether our findings with specific miRNA loci were related to timing before diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-183 Breast Neoplasms 26124344 Differentially expressed miRNAs from PBMCs may be potential non-invasive biomarkers for breast cancer prediction. Larger prospective studies are required to confirm whether our findings with specific miRNA loci were related to timing before diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-451a Breast Neoplasms 26124344 Differentially expressed miRNAs from PBMCs may be potential non-invasive biomarkers for breast cancer prediction. Larger prospective studies are required to confirm whether our findings with specific miRNA loci were related to timing before diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-708 Breast Neoplasms 26124344 Differentially expressed miRNAs from PBMCs may be potential non-invasive biomarkers for breast cancer prediction. Larger prospective studies are required to confirm whether our findings with specific miRNA loci were related to timing before diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-146a Chronic Hepatitis B 26131144 Positive correlation was found between the levels of hsa- miR-146a and ALT circulation_biomarker_diagnosis_ns hsa-mir-122 "Carcinoma, Hepatocellular" 26133725 The combination of serum miR-16 and serum AFP is a significant improvement on the current best practice of serum AFP for HCC in HCVpositive patients. Serum miR-199a and miR-16 could be used as potential indicators of the progress of HCC. circulation_biomarker_diagnosis_ns hsa-mir-16 "Carcinoma, Hepatocellular" 26133725 The combination of serum miR-16 and serum AFP is a significant improvement on the current best practice of serum AFP for HCC in HCVpositive patients. Serum miR-199a and miR-18 could be used as potential indicators of the progress of HCC. circulation_biomarker_diagnosis_ns hsa-mir-199a "Carcinoma, Hepatocellular" 26133725 The combination of serum miR-16 and serum AFP is a significant improvement on the current best practice of serum AFP for HCC in HCVpositive patients. Serum miR-199a and miR-17 could be used as potential indicators of the progress of HCC. circulation_biomarker_diagnosis_ns hsa-mir-103 Colorectal Carcinoma 26134152 Circulating miR-103 and miR-720 as novel serum biomarkers for patients with colorectal cancer. circulation_biomarker_diagnosis_ns hsa-mir-720 Colorectal Carcinoma 26134152 Circulating miR-103 and miR-720 as novel serum biomarkers for patients with colorectal cancer. circulation_biomarker_diagnosis_ns hsa-mir-19b "Carcinoma, Lung" 26146958 The assessment of miRs-19b-3p and -29b-3p miRNAs may provide a new diagnostic approach for the early detection of non-small cell lung cancer circulation_biomarker_diagnosis_ns hsa-mir-100 Coronary Atherosclerosis 26159918 "miR-221, miR-155, miR-100 and hsa-miR-1273,expression level can be used as potential markersfor early coronary atherosclerotic plaque formation." circulation_biomarker_diagnosis_ns hsa-mir-1273 Coronary Atherosclerosis 26159918 "miR-221, miR-155, miR-100 and hsa-miR-1273,expression level can be used as potential markersfor early coronary atherosclerotic plaque formation." circulation_biomarker_diagnosis_ns hsa-mir-155 Coronary Atherosclerosis 26159918 "miR-221, miR-155, miR-100 and hsa-miR-1273,expression level can be used as potential markersfor early coronary atherosclerotic plaque formation." circulation_biomarker_diagnosis_ns hsa-mir-221 Coronary Atherosclerosis 26159918 "miR-221, miR-155, miR-100 and hsa-miR-1273,expression level can be used as potential markersfor early coronary atherosclerotic plaque formation." circulation_biomarker_diagnosis_ns hsa-mir-103 Prediabetes 26164754 Dysregulated miR-103 and miR-143 expression in peripheral blood mononuclear cells from induced prediabetes and type 2 diabetes rats. circulation_biomarker_diagnosis_ns hsa-mir-143 Prediabetes 26164754 Dysregulated miR-103 and miR-143 expression in peripheral blood mononuclear cells from induced prediabetes and type 2 diabetes rats. circulation_biomarker_diagnosis_ns hsa-mir-25 "Carcinoma, Thyroid, Papillary" 26168287 Circulating miR-25-3p and miR-451a May Be Potential Biomarkers for the Diagnosis of Papillary Thyroid Carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-451a "Carcinoma, Thyroid, Papillary" 26168287 Circulating miR-25-3p and miR-451a May Be Potential Biomarkers for the Diagnosis of Papillary Thyroid Carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-141 "Carcinoma, Lung, Non-Small-Cell" 26202143 we identified a serum 4-miRNA signature that discriminated with high accuracy lung cancer patients from NC. Further prospective validation of this miRNA signature is warranted. circulation_biomarker_diagnosis_ns hsa-mir-193b "Carcinoma, Lung, Non-Small-Cell" 26202143 we identified a serum 4-miRNA signature that discriminated with high accuracy lung cancer patients from NC. Further prospective validation of this miRNA signature is warranted. circulation_biomarker_diagnosis_ns hsa-mir-200b "Carcinoma, Lung, Non-Small-Cell" 26202143 we identified a serum 4-miRNA signature that discriminated with high accuracy lung cancer patients from NC. Further prospective validation of this miRNA signature is warranted. circulation_biomarker_diagnosis_ns hsa-mir-301 "Carcinoma, Lung, Non-Small-Cell" 26202143 we identified a serum 4-miRNA signature that discriminated with high accuracy lung cancer patients from NC. Further prospective validation of this miRNA signature is warranted. circulation_biomarker_diagnosis_ns hsa-mir-200 Endometriosis 26206343 Circulating miR-200-family micro-RNAs have altered plasma levels in patients with endometriosis and vary with blood collection time. circulation_biomarker_diagnosis_ns hsa-mir-10b Melanoma 26208390 "Evaluation of the expressions pattern of miR-10b, 21, 200c, 373 and 520c to find the correlation between epithelial-to-mesenchymal transition and melanoma stem cell potential in isolated cancer stem cells." circulation_biomarker_diagnosis_ns hsa-mir-200c Melanoma 26208390 "Evaluation of the expressions pattern of miR-10b, 21, 200c, 373 and 520c to find the correlation between epithelial-to-mesenchymal transition and melanoma stem cell potential in isolated cancer stem cells." circulation_biomarker_diagnosis_ns hsa-mir-21 Melanoma 26208390 "Evaluation of the expressions pattern of miR-10b, 21, 200c, 373 and 520c to find the correlation between epithelial-to-mesenchymal transition and melanoma stem cell potential in isolated cancer stem cells." circulation_biomarker_diagnosis_ns hsa-mir-373 Melanoma 26208390 "Evaluation of the expressions pattern of miR-10b, 21, 200c, 373 and 520c to find the correlation between epithelial-to-mesenchymal transition and melanoma stem cell potential in isolated cancer stem cells." circulation_biomarker_diagnosis_ns hsa-mir-520c Melanoma 26208390 "Evaluation of the expressions pattern of miR-10b, 21, 200c, 373 and 520c to find the correlation between epithelial-to-mesenchymal transition and melanoma stem cell potential in isolated cancer stem cells." circulation_biomarker_diagnosis_ns hsa-mir-21 Heart Failure 26211628 MiR-21 levels were not different among the groups. circulation_biomarker_diagnosis_ns hsa-let-7d Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-let-7e Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-181c Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-18b Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-21 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-223 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-26a Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-29b Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-29c Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-324 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-328 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-335 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-345 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-362 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-365 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-494 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-532 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-579 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-629 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-744 Systemic Lupus Erythematosus 26225955 MicroRNA Profiling of B Cell Subsets from Systemic Lupus Erythematosus Patients Reveals Promising Novel Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-21 Intestinal Schistosomiasis 26230095 "The inconsistent levels of the host circulating miRNAs, miR-122, miR-21 and miR-34a in serum were confirmed in the two murine models during infection" circulation_biomarker_diagnosis_ns hsa-mir-486 "Carcinoma, Lung, Non-Small-Cell" 26237047 The results suggest that miR-486 and miR-150 could be potential blood-based biomarkers for early diagnosis of NSCLC. Monitoring change of miR-486 expression in plasma might be an effective and non-invasive method for recurrence prediction of early-staged NSCLC patients. circulation_biomarker_diagnosis_ns hsa-mir-146b Synovial Sarcoma 26250552 "Our results have identified a specific whole blood miRNA signature that may serve as an independent biomarker for the diagnosis of local recurrence or distant metastasis of synovial sarcoma. It even distinguishes synovial sarcoma from other sarcoma subtypes, thus potentially serving as a specific biomarker for synovial sarcoma." circulation_biomarker_diagnosis_ns hsa-mir-148b Synovial Sarcoma 26250552 "Our results have identified a specific whole blood miRNA signature that may serve as an independent biomarker for the diagnosis of local recurrence or distant metastasis of synovial sarcoma. It even distinguishes synovial sarcoma from other sarcoma subtypes, thus potentially serving as a specific biomarker for synovial sarcoma." circulation_biomarker_diagnosis_ns hsa-mir-195 Synovial Sarcoma 26250552 "Our results have identified a specific whole blood miRNA signature that may serve as an independent biomarker for the diagnosis of local recurrence or distant metastasis of synovial sarcoma. It even distinguishes synovial sarcoma from other sarcoma subtypes, thus potentially serving as a specific biomarker for synovial sarcoma." circulation_biomarker_diagnosis_ns hsa-mir-223 Synovial Sarcoma 26250552 "Our results have identified a specific whole blood miRNA signature that may serve as an independent biomarker for the diagnosis of local recurrence or distant metastasis of synovial sarcoma. It even distinguishes synovial sarcoma from other sarcoma subtypes, thus potentially serving as a specific biomarker for synovial sarcoma." circulation_biomarker_diagnosis_ns hsa-mir-500b Synovial Sarcoma 26250552 "Our results have identified a specific whole blood miRNA signature that may serve as an independent biomarker for the diagnosis of local recurrence or distant metastasis of synovial sarcoma. It even distinguishes synovial sarcoma from other sarcoma subtypes, thus potentially serving as a specific biomarker for synovial sarcoma." circulation_biomarker_diagnosis_ns hsa-mir-505 Synovial Sarcoma 26250552 "Our results have identified a specific whole blood miRNA signature that may serve as an independent biomarker for the diagnosis of local recurrence or distant metastasis of synovial sarcoma. It even distinguishes synovial sarcoma from other sarcoma subtypes, thus potentially serving as a specific biomarker for synovial sarcoma." circulation_biomarker_diagnosis_ns hsa-mir-99a Synovial Sarcoma 26250552 "Our results have identified a specific whole blood miRNA signature that may serve as an independent biomarker for the diagnosis of local recurrence or distant metastasis of synovial sarcoma. It even distinguishes synovial sarcoma from other sarcoma subtypes, thus potentially serving as a specific biomarker for synovial sarcoma." circulation_biomarker_diagnosis_ns hsa-mir-210 Bladder Neoplasms 26252880 "Serum miR-210 Contributes to Tumor Detection, Stage Prediction and Dynamic Surveillance in Patients with Bladder Cancer." circulation_biomarker_diagnosis_ns hsa-mir-192 Nephrotic Syndrome 26261628 Differential microRNA expression in the serum of patients with nephrotic syndrome and clinical correlation analysis. circulation_biomarker_diagnosis_ns hsa-mir-210 Nephrotic Syndrome 26261628 Differential microRNA expression in the serum of patients with nephrotic syndrome and clinical correlation analysis. circulation_biomarker_diagnosis_ns hsa-mir-30a Nephrotic Syndrome 26261628 Differential microRNA expression in the serum of patients with nephrotic syndrome and clinical correlation analysis. circulation_biomarker_diagnosis_ns hsa-mir-586 Nephrotic Syndrome 26261628 Differential microRNA expression in the serum of patients with nephrotic syndrome and clinical correlation analysis. circulation_biomarker_diagnosis_ns hsa-mir-942 Nephrotic Syndrome 26261628 Differential microRNA expression in the serum of patients with nephrotic syndrome and clinical correlation analysis. circulation_biomarker_diagnosis_ns hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 26262588 "Serum miR-21 and miR-34a are potentially useful diagnostic biomarkers of PDAC. In addition, our results suggest that these miRNAs are not differentially expressed in saliva, making them unsuitable for use as noninvasive biomarkers for diagnostic purposes." circulation_biomarker_diagnosis_ns hsa-mir-34a "Adenocarcinoma, Pancreatic Ductal" 26262588 "Serum miR-21 and miR-34a are potentially useful diagnostic biomarkers of PDAC. In addition, our results suggest that these miRNAs are not differentially expressed in saliva, making them unsuitable for use as noninvasive biomarkers for diagnostic purposes." circulation_biomarker_diagnosis_ns hsa-mir-143 "Carcinoma, Hepatocellular, HBV-Related" 26267843 "The miRNA expression profile of PBMCs is altered in patients with HBV-ACLF, and a signature of six miRNAs may be a promising biomarker for HBV-ACLF progression." circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Hepatocellular, HBV-Related" 26267843 "The miRNA expression profile of PBMCs is altered in patients with HBV-ACLF, and a signature of six miRNAs may be a promising biomarker for HBV-ACLF progression." circulation_biomarker_diagnosis_ns hsa-mir-34c "Carcinoma, Hepatocellular, HBV-Related" 26267843 "The miRNA expression profile of PBMCs is altered in patients with HBV-ACLF, and a signature of six miRNAs may be a promising biomarker for HBV-ACLF progression." circulation_biomarker_diagnosis_ns hsa-mir-374a "Carcinoma, Hepatocellular, HBV-Related" 26267843 "The miRNA expression profile of PBMCs is altered in patients with HBV-ACLF, and a signature of six miRNAs may be a promising biomarker for HBV-ACLF progression." circulation_biomarker_diagnosis_ns hsa-mir-542 "Carcinoma, Hepatocellular, HBV-Related" 26267843 "The miRNA expression profile of PBMCs is altered in patients with HBV-ACLF, and a signature of six miRNAs may be a promising biomarker for HBV-ACLF progression." circulation_biomarker_diagnosis_ns hsa-mir-155 "Carcinoma, Hepatocellular, HCV-Related" 26272105 "This study shows that some microRNAs are differently expressed in peripheral blood mononuclear cells from hepatitis C virus patients who develop hepatocellular carcinoma or lymphoma, while others share a common behavior. Thus,analysis of the expression of microRNAs could be a noninvasive marker of hepatitis C virus-related carcinogenesis. This analysis could be a suitable tool for identifying the existence of a malignancy and also discriminating between these two hepatitis C virus-related cancers." circulation_biomarker_diagnosis_ns hsa-mir-16 "Carcinoma, Hepatocellular, HCV-Related" 26272105 "This study shows that some microRNAs are differently expressed in peripheral blood mononuclear cells from hepatitis C virus patients who develop hepatocellular carcinoma or lymphoma, while others share a common behavior. Thus,analysis of the expression of microRNAs could be a noninvasive marker of hepatitis C virus-related carcinogenesis. This analysis could be a suitable tool for identifying the existence of a malignancy and also discriminating between these two hepatitis C virus-related cancers." circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Hepatocellular, HCV-Related" 26272105 "This study shows that some microRNAs are differently expressed in peripheral blood mononuclear cells from hepatitis C virus patients who develop hepatocellular carcinoma or lymphoma, while others share a common behavior. Thus,analysis of the expression of microRNAs could be a noninvasive marker of hepatitis C virus-related carcinogenesis. This analysis could be a suitable tool for identifying the existence of a malignancy and also discriminating between these two hepatitis C virus-related cancers." circulation_biomarker_diagnosis_ns hsa-mir-26b "Carcinoma, Hepatocellular, HCV-Related" 26272105 "This study shows that some microRNAs are differently expressed in peripheral blood mononuclear cells from hepatitis C virus patients who develop hepatocellular carcinoma or lymphoma, while others share a common behavior. Thus,analysis of the expression of microRNAs could be a noninvasive marker of hepatitis C virus-related carcinogenesis. This analysis could be a suitable tool for identifying the existence of a malignancy and also discriminating between these two hepatitis C virus-related cancers." circulation_biomarker_diagnosis_ns hsa-mir-183 "Carcinoma, Hepatocellular" 26278140 "Sensitivity and specificity of miR-183 as a diagnostic marker of HCC were 57.9% and 76.2% in serum, and 78.9% and 81.0% in plasma" circulation_biomarker_diagnosis_ns hsa-mir-122 Hepatitis C Virus Infection 26283876 Dysregulated Serum MicroRNA Expression Profile and Potential Biomarkers in Hepatitis C Virus-infected Patients. circulation_biomarker_diagnosis_ns hsa-mir-134 Hepatitis C Virus Infection 26283876 Dysregulated Serum MicroRNA Expression Profile and Potential Biomarkers in Hepatitis C Virus-infected Patients. circulation_biomarker_diagnosis_ns hsa-mir-424 Hepatitis C Virus Infection 26283876 Dysregulated Serum MicroRNA Expression Profile and Potential Biomarkers in Hepatitis C Virus-infected Patients. circulation_biomarker_diagnosis_ns hsa-mir-629 Hepatitis C Virus Infection 26283876 Dysregulated Serum MicroRNA Expression Profile and Potential Biomarkers in Hepatitis C Virus-infected Patients. circulation_biomarker_diagnosis_ns hsa-mir-21 Glioma 26284486 "Therefore, we concluded that the exosomal miR-21 levels could be demonstrated as a promising indicator for glioma diagnosis and prognosis, particularly with values to predict tumor recurrence or metastasis." circulation_biomarker_diagnosis_ns hsa-mir-150 Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-15b Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-199a Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-211 Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-33a Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-424 Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-4487 Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-4706 Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-4731 Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-506 Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-509 Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-514 Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-514a Melanoma 26288839 This panel was found to be superior to currently used serological markers for melanoma progression circulation_biomarker_diagnosis_ns hsa-mir-17 Bronchopulmonary Dysplasia 26291337 Our data are the first to demonstrate altered expression of the miR-17-92 cluster in bronchopulmonary dysplasia. The consistency between our autopsy and plasma findings further support our working hypothesis that the miR-17-92 cluster contributes to the molecular pathogenesis of bronchopulmonary dysplasia. circulation_biomarker_diagnosis_ns hsa-mir-367 Neoplasms [unspecific] 26306513 Targeted miRNA-based blood tests for miR-371-3 and miR-367 clusters are currently under development and hold a great promise for the future. circulation_biomarker_diagnosis_ns hsa-mir-185 "Squamous Cell Carcinoma, Esophageal" 26316588 "In conclusion, our findings shed novel light on the role of miR-185/RAGE in ESCC metastasis, and plasma miR-185 has potential as a novel diagnostic biomarker in ESCC." circulation_biomarker_diagnosis_ns hsa-mir-196b "Leukemia, Myeloid, Acute" 26317787 "These results suggest that microRNA-155 is a potential diagnostic biomarker for all subgroups of paediatric AML, whereas microRNA-196b is specific for subgroups M4-M5." circulation_biomarker_diagnosis_ns hsa-mir-210 Chronic Hepatitis B 26319884 "Serum miR-210 can be used as an indicator of HBV replication and translation, and a potential marker of necroinflammation in patients with CHB." circulation_biomarker_diagnosis_ns hsa-mir-191 "Carcinoma, Urothelial, Upper Tract" 26323574 Identification of circulating microRNA signatures for upper tract urothelial carcinoma detection. circulation_biomarker_diagnosis_ns hsa-mir-22 "Carcinoma, Urothelial, Upper Tract" 26323574 Identification of circulating microRNA signatures for upper tract urothelial carcinoma detection. circulation_biomarker_diagnosis_ns hsa-mir-26a "Carcinoma, Urothelial, Upper Tract" 26323574 Identification of circulating microRNA signatures for upper tract urothelial carcinoma detection. circulation_biomarker_diagnosis_ns hsa-mir-33b "Carcinoma, Urothelial, Upper Tract" 26323574 Identification of circulating microRNA signatures for upper tract urothelial carcinoma detection. circulation_biomarker_diagnosis_ns hsa-mir-423 "Carcinoma, Urothelial, Upper Tract" 26323574 Identification of circulating microRNA signatures for upper tract urothelial carcinoma detection. circulation_biomarker_diagnosis_ns hsa-mir-431 "Carcinoma, Urothelial, Upper Tract" 26323574 Identification of circulating microRNA signatures for upper tract urothelial carcinoma detection. circulation_biomarker_diagnosis_ns hsa-mir-664a "Carcinoma, Urothelial, Upper Tract" 26323574 Identification of circulating microRNA signatures for upper tract urothelial carcinoma detection. circulation_biomarker_diagnosis_ns hsa-mir-92a "Carcinoma, Urothelial, Upper Tract" 26323574 Identification of circulating microRNA signatures for upper tract urothelial carcinoma detection. circulation_biomarker_diagnosis_ns hsa-let-7b Atherosclerosis 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-let-7b Stroke 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-22 Atherosclerosis 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-22 Stroke 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-221 Atherosclerosis 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-221 Stroke 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-26a Atherosclerosis 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-26a Stroke 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-26b Atherosclerosis 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-26b Stroke 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-27b Atherosclerosis 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-27b Stroke 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-29b Atherosclerosis 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-29b Stroke 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-30b Atherosclerosis 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-30b Stroke 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-30e Atherosclerosis 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-30e Stroke 26333279 "A specific circulating miRNAs profile is associated with migraine without aura. Remarkably, the same miRNAs are known to be modulated in the setting of atherosclerosis and stroke in humans. This study represents a first step towards further characterization of MO diagnosis/pathophysiology, also in relation to its link with cardiovascular risk." circulation_biomarker_diagnosis_ns hsa-mir-146a Myocardial Infarction 26337652 Circulating miR-146a and miR-21 may be novel biomarkers predictive of LVR after acute MI. Their combination may better predict LVR than either alone. circulation_biomarker_diagnosis_ns hsa-mir-21 Myocardial Infarction 26337652 Circulating miR-146a and miR-21 may be novel biomarkers predictive of LVR after acute MI. Their combination may better predict LVR than either alone. circulation_biomarker_diagnosis_ns hsa-let-7b "Carcinoma, Thyroid, Papillary" 26341226 MicroRNA is differentially expressed in the serum of patients with PTC. Serum miRNA has the potential to aid in thyroid cancer diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-10a "Carcinoma, Thyroid, Papillary" 26341226 MicroRNA is differentially expressed in the serum of patients with PTC. Serum miRNA has the potential to aid in thyroid cancer diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-146a "Carcinoma, Thyroid, Papillary" 26341226 MicroRNA is differentially expressed in the serum of patients with PTC. Serum miRNA has the potential to aid in thyroid cancer diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-199b "Carcinoma, Thyroid, Papillary" 26341226 MicroRNA is differentially expressed in the serum of patients with PTC. Serum miRNA has the potential to aid in thyroid cancer diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-27a Acute Heart Failure 26345695 Fifteen miRNAs found in the discovery phase to differ most significantly between healthy controls and patients with AHF circulation_biomarker_diagnosis_ns hsa-mir-1 Essential Hypertension 26358152 Hypertrophic and antihypertrophic microRNA levels in peripheral blood mononuclear cells and their relationship to left ventricular hypertrophy in patients with essential hypertension. circulation_biomarker_diagnosis_ns hsa-mir-133a Essential Hypertension 26358152 Hypertrophic and antihypertrophic microRNA levels in peripheral blood mononuclear cells and their relationship to left ventricular hypertrophy in patients with essential hypertension. circulation_biomarker_diagnosis_ns hsa-mir-208b Essential Hypertension 26358152 Hypertrophic and antihypertrophic microRNA levels in peripheral blood mononuclear cells and their relationship to left ventricular hypertrophy in patients with essential hypertension. circulation_biomarker_diagnosis_ns hsa-mir-21 Essential Hypertension 26358152 Hypertrophic and antihypertrophic microRNA levels in peripheral blood mononuclear cells and their relationship to left ventricular hypertrophy in patients with essential hypertension. circulation_biomarker_diagnosis_ns hsa-mir-26b Essential Hypertension 26358152 Hypertrophic and antihypertrophic microRNA levels in peripheral blood mononuclear cells and their relationship to left ventricular hypertrophy in patients with essential hypertension. circulation_biomarker_diagnosis_ns hsa-mir-499 Essential Hypertension 26358152 Hypertrophic and antihypertrophic microRNA levels in peripheral blood mononuclear cells and their relationship to left ventricular hypertrophy in patients with essential hypertension. circulation_biomarker_diagnosis_ns hsa-mir-26a Osteosarcoma 26377680 "In conclusion, our findings suggested that expression level of miR-26a and miR-27a contributes to aggressive progression of this malignancy.Therefore, may have clinical potentials as a non-invasive diagnostic/prognostic biomarker for osteosarcoma patients." circulation_biomarker_diagnosis_ns hsa-mir-27a Osteosarcoma 26377680 "In conclusion, our findings suggested that expression level of miR-26a and miR-27a contributes to aggressive progression of this malignancy.Therefore, may have clinical potentials as a non-invasive diagnostic/prognostic biomarker for osteosarcoma patients." circulation_biomarker_diagnosis_ns hsa-mir-146a Epilepsy 26382856 "Those miRNAs that are altered in plasma before the first spontaneous seizure,like miR-9a-3p, may be proposed as putative biomarkers of epileptogenesis." circulation_biomarker_diagnosis_ns hsa-mir-181c Epilepsy 26382856 "Those miRNAs that are altered in plasma before the first spontaneous seizure,like miR-9a-3p, may be proposed as putative biomarkers of epileptogenesis." circulation_biomarker_diagnosis_ns hsa-mir-21 Epilepsy 26382856 "Those miRNAs that are altered in plasma before the first spontaneous seizure,like miR-9a-3p, may be proposed as putative biomarkers of epileptogenesis." circulation_biomarker_diagnosis_ns hsa-mir-23a Epilepsy 26382856 "Those miRNAs that are altered in plasma before the first spontaneous seizure,like miR-9a-3p, may be proposed as putative biomarkers of epileptogenesis." circulation_biomarker_diagnosis_ns hsa-mir-9a Epilepsy 26382856 "Those miRNAs that are altered in plasma before the first spontaneous seizure,like miR-9a-3p, may be proposed as putative biomarkers of epileptogenesis." circulation_biomarker_diagnosis_ns hsa-mir-103 Obesity 26406295 This study provides the first identification of altered circulating miRNAs in maternal obesity and suggests a possible role of such miRNAS as markers for pre- and postnatal growth. circulation_biomarker_diagnosis_ns hsa-mir-122 Obesity 26406295 This study provides the first identification of altered circulating miRNAs in maternal obesity and suggests a possible role of such miRNAS as markers for pre- and postnatal growth. circulation_biomarker_diagnosis_ns hsa-mir-130a Obesity 26406295 This study provides the first identification of altered circulating miRNAs in maternal obesity and suggests a possible role of such miRNAS as markers for pre- and postnatal growth. circulation_biomarker_diagnosis_ns hsa-mir-150 Obesity 26406295 This study provides the first identification of altered circulating miRNAs in maternal obesity and suggests a possible role of such miRNAS as markers for pre- and postnatal growth. circulation_biomarker_diagnosis_ns hsa-mir-221 Obesity 26406295 This study provides the first identification of altered circulating miRNAs in maternal obesity and suggests a possible role of such miRNAS as markers for pre- and postnatal growth. circulation_biomarker_diagnosis_ns hsa-mir-29c Obesity 26406295 This study provides the first identification of altered circulating miRNAs in maternal obesity and suggests a possible role of such miRNAS as markers for pre- and postnatal growth. circulation_biomarker_diagnosis_ns hsa-mir-30a Obesity 26406295 This study provides the first identification of altered circulating miRNAs in maternal obesity and suggests a possible role of such miRNAS as markers for pre- and postnatal growth. circulation_biomarker_diagnosis_ns hsa-mir-324 Obesity 26406295 This study provides the first identification of altered circulating miRNAs in maternal obesity and suggests a possible role of such miRNAS as markers for pre- and postnatal growth. circulation_biomarker_diagnosis_ns hsa-mir-340 Obesity 26406295 This study provides the first identification of altered circulating miRNAs in maternal obesity and suggests a possible role of such miRNAS as markers for pre- and postnatal growth. circulation_biomarker_diagnosis_ns hsa-mir-375 Obesity 26406295 This study provides the first identification of altered circulating miRNAs in maternal obesity and suggests a possible role of such miRNAS as markers for pre- and postnatal growth. circulation_biomarker_diagnosis_ns hsa-mir-652 Obesity 26406295 This study provides the first identification of altered circulating miRNAs in maternal obesity and suggests a possible role of such miRNAS as markers for pre- and postnatal growth. circulation_biomarker_diagnosis_ns hsa-mir-99b Obesity 26406295 This study provides the first identification of altered circulating miRNAs in maternal obesity and suggests a possible role of such miRNAS as markers for pre- and postnatal growth. circulation_biomarker_diagnosis_ns hsa-let-7e "Stroke, Ischemic" 26415639 MicroRNA let-7e Is a Potential Circulating Biomarker of Acute Stage Ischemic Stroke. circulation_biomarker_diagnosis_ns hsa-mir-210 "Carcinoma, Renal Cell" 26426010 Combination of MiR-378 and MiR-210 Serum Levels Enables Sensitive Detection of Renal Cell Carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-378 "Carcinoma, Renal Cell" 26426010 Combination of MiR-378 and MiR-210 Serum Levels Enables Sensitive Detection of Renal Cell Carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-3151 "Leukemia, Myeloid, Acute" 26430723 "In conclusion, the analysis of miR-3151 and BAALC expression may well contribute to an improved prognostic stratification of younger patients with IR-AML." circulation_biomarker_diagnosis_ns hsa-let-7i Heart Failure 26430739 "Our data show a different miR expression pattern after LVAD support, suggesting that differentially expressed miRs are partially responsible for the cardiac morphological and functional changes observed after support. However, the miR expression patterns do not seem to significantly differ between pf- and cf-LVAD implying that most cardiac changes or clinical outcomes specific to each device do not relate to differences in miR expression levels." circulation_biomarker_diagnosis_ns hsa-mir-129 Heart Failure 26430739 "Our data show a different miR expression pattern after LVAD support, suggesting that differentially expressed miRs are partially responsible for the cardiac morphological and functional changes observed after support. However, the miR expression patterns do not seem to significantly differ between pf- and cf-LVAD implying that most cardiac changes or clinical outcomes specific to each device do not relate to differences in miR expression levels." circulation_biomarker_diagnosis_ns hsa-mir-146a Heart Failure 26430739 "Our data show a different miR expression pattern after LVAD support, suggesting that differentially expressed miRs are partially responsible for the cardiac morphological and functional changes observed after support. However, the miR expression patterns do not seem to significantly differ between pf- and cf-LVAD implying that most cardiac changes or clinical outcomes specific to each device do not relate to differences in miR expression levels." circulation_biomarker_diagnosis_ns hsa-mir-155 Heart Failure 26430739 "Our data show a different miR expression pattern after LVAD support, suggesting that differentially expressed miRs are partially responsible for the cardiac morphological and functional changes observed after support. However, the miR expression patterns do not seem to significantly differ between pf- and cf-LVAD implying that most cardiac changes or clinical outcomes specific to each device do not relate to differences in miR expression levels." circulation_biomarker_diagnosis_ns hsa-mir-21 Heart Failure 26430739 "Our data show a different miR expression pattern after LVAD support, suggesting that differentially expressed miRs are partially responsible for the cardiac morphological and functional changes observed after support. However, the miR expression patterns do not seem to significantly differ between pf- and cf-LVAD implying that most cardiac changes or clinical outcomes specific to each device do not relate to differences in miR expression levels." circulation_biomarker_diagnosis_ns hsa-mir-221 Heart Failure 26430739 "Our data show a different miR expression pattern after LVAD support, suggesting that differentially expressed miRs are partially responsible for the cardiac morphological and functional changes observed after support. However, the miR expression patterns do not seem to significantly differ between pf- and cf-LVAD implying that most cardiac changes or clinical outcomes specific to each device do not relate to differences in miR expression levels." circulation_biomarker_diagnosis_ns hsa-mir-222 Heart Failure 26430739 "Our data show a different miR expression pattern after LVAD support, suggesting that differentially expressed miRs are partially responsible for the cardiac morphological and functional changes observed after support. However, the miR expression patterns do not seem to significantly differ between pf- and cf-LVAD implying that most cardiac changes or clinical outcomes specific to each device do not relate to differences in miR expression levels." circulation_biomarker_diagnosis_ns hsa-mir-378 Heart Failure 26430739 "Our data show a different miR expression pattern after LVAD support, suggesting that differentially expressed miRs are partially responsible for the cardiac morphological and functional changes observed after support. However, the miR expression patterns do not seem to significantly differ between pf- and cf-LVAD implying that most cardiac changes or clinical outcomes specific to each device do not relate to differences in miR expression levels." circulation_biomarker_diagnosis_ns hsa-mir-200 "Carcinoma, Hepatocellular" 26447841 Circulating microRNA-200 family members are significantly deregulated in patients with HCC and liver cirrhosis. Further studies are necessary to confirm the diagnostic value of the microRNA-200 family as accurate serum marker for cirrhosis-associated HCC. circulation_biomarker_diagnosis_ns hsa-mir-185 Glioma 26458593 These findings suggest that plasma miR-185 has become potential biomarkers for glioma and may be useful in clinical management for glioma patients. circulation_biomarker_diagnosis_ns hsa-mir-126 Chronic Kidney Disease 26475583 Plasma levels of microRNA in chronic kidney disease: patterns in acute and chronic exercise. circulation_biomarker_diagnosis_ns hsa-mir-146a Chronic Kidney Disease 26475583 Plasma levels of microRNA in chronic kidney disease: patterns in acute and chronic exercise. circulation_biomarker_diagnosis_ns hsa-mir-150 Chronic Kidney Disease 26475583 Plasma levels of microRNA in chronic kidney disease: patterns in acute and chronic exercise. circulation_biomarker_diagnosis_ns hsa-mir-21 Chronic Kidney Disease 26475583 Plasma levels of microRNA in chronic kidney disease: patterns in acute and chronic exercise. circulation_biomarker_diagnosis_ns hsa-mir-210 Chronic Kidney Disease 26475583 Plasma levels of microRNA in chronic kidney disease: patterns in acute and chronic exercise. circulation_biomarker_diagnosis_ns hsa-mir-199a Breast Neoplasms 26476723 "Our data demonstrate that the SdM-RT-PCR assay is an effective breast cancer profiling method that utilizes very small volumes and is compatible with Biobank.Furthermore, the identified 3-miRNA signature is a promising circulating biomarker for breast cancer diagnosis." circulation_biomarker_diagnosis_ns hsa-mir-29c Breast Neoplasms 26476723 "Our data demonstrate that the SdM-RT-PCR assay is an effective breast cancer profiling method that utilizes very small volumes and is compatible with Biobank.Furthermore, the identified 3-miRNA signature is a promising circulating biomarker for breast cancer diagnosis." circulation_biomarker_diagnosis_ns hsa-mir-424 Breast Neoplasms 26476723 "Our data demonstrate that the SdM-RT-PCR assay is an effective breast cancer profiling method that utilizes very small volumes and is compatible with Biobank.Furthermore, the identified 3-miRNA signature is a promising circulating biomarker for breast cancer diagnosis." circulation_biomarker_diagnosis_ns hsa-mir-10a Chronic Hepatitis B 26483130 We constructed serum miRNA panels with considerable clinical value in diagnosing PNALT. circulation_biomarker_diagnosis_ns hsa-mir-122 Chronic Hepatitis B 26483130 We constructed serum miRNA panels with considerable clinical value in diagnosing PNALT. circulation_biomarker_diagnosis_ns hsa-mir-192 Chronic Hepatitis B 26483130 We constructed serum miRNA panels with considerable clinical value in diagnosing PNALT. circulation_biomarker_diagnosis_ns hsa-mir-26a Chronic Hepatitis B 26483130 We constructed serum miRNA panels with considerable clinical value in diagnosing PNALT. circulation_biomarker_diagnosis_ns hsa-mir-30b Chronic Hepatitis B 26483130 We constructed serum miRNA panels with considerable clinical value in diagnosing PNALT. circulation_biomarker_diagnosis_ns hsa-mir-511 Chronic Hepatitis B 26483130 We constructed serum miRNA panels with considerable clinical value in diagnosing PNALT. circulation_biomarker_diagnosis_ns hsa-mir-574 Chronic Hepatitis B 26483130 We constructed serum miRNA panels with considerable clinical value in diagnosing PNALT. circulation_biomarker_diagnosis_ns hsa-mir-885 Chronic Hepatitis B 26483130 We constructed serum miRNA panels with considerable clinical value in diagnosing PNALT. circulation_biomarker_diagnosis_ns hsa-mir-98 Chronic Hepatitis B 26483130 We constructed serum miRNA panels with considerable clinical value in diagnosing PNALT. circulation_biomarker_diagnosis_ns hsa-mir-339 Ovarian Neoplasms 26485143 "10 miRNAs (miR-193a-5p, miR-375, miR-339-3p, miR-340-5p, miR-532-3p, miR-133a-3p, miR-25-3p, miR-10a-5p, miR-616-5p, and miR-148b-5p) displayed fold changes in concentration ranging from -2.9 to 4 (p<0.05), in recurrent platinum resistant ovarian cancer patients" circulation_biomarker_diagnosis_ns hsa-mir-139 Behcet Disease 26486198 miR199-3p and miR720 deserve further confirmation as biomarkers of BD in larger studies. PBMCs from active BD displayed a unique signature of microRNAs which may be implicated in regulation of innate immunity activation and T-cell function. circulation_biomarker_diagnosis_ns hsa-mir-720 Behcet Disease 26486198 miR199-3p and miR720 deserve further confirmation as biomarkers of BD in larger studies. PBMCs from active BD displayed a unique signature of microRNAs which may be implicated in regulation of innate immunity activation and T-cell function. circulation_biomarker_diagnosis_ns hsa-mir-143 Bladder Neoplasms 26489968 MiRNAs detected in urine and serum/plasma will demonstrate their potentiality to describe the variegated scenario of BC and to become relevant clinical markers. circulation_biomarker_diagnosis_ns hsa-mir-92a Bladder Neoplasms 26489968 MiRNAs detected in urine and serum/plasma will demonstrate their potentiality to describe the variegated scenario of BC and to become relevant clinical markers. circulation_biomarker_diagnosis_ns hsa-mir-126 Diabetes Mellitus 26498351 MiR-21-5p and miR-126a-3p levels in plasma and circulating angiogenic cells:relationship with type 2 diabetes complications. circulation_biomarker_diagnosis_ns hsa-mir-21 Diabetes Mellitus 26498351 MiR-21-5p and miR-126a-3p levels in plasma and circulating angiogenic cells:relationship with type 2 diabetes complications. circulation_biomarker_diagnosis_ns hsa-mir-1 Heart Failure 26498537 Dysregulation of miR-1 and miR-21 expression may be essential for the development of HF; miR-1 might become a biomarker for predicting HF exacerbation. circulation_biomarker_diagnosis_ns hsa-mir-208a Heart Failure 26498537 Dysregulation of miR-1 and miR-21 expression may be essential for the development of HF; miR-1 might become a biomarker for predicting HF exacerbation. circulation_biomarker_diagnosis_ns hsa-mir-21 Heart Failure 26498537 Dysregulation of miR-1 and miR-21 expression may be essential for the development of HF; miR-1 might become a biomarker for predicting HF exacerbation. circulation_biomarker_diagnosis_ns hsa-mir-744 Pancreatic Neoplasms 26505678 "Plasma miR-744 might be useful biomarker for screening PCa,monitoring, and predicting poor prognosis and chemoresistance in PCa patients." circulation_biomarker_diagnosis_ns hsa-mir-494 "Carcinoma, Hepatocellular" 26509672 "Therefore, we show that circulating microRNAs deserve attention as non-invasive biomarkers in the diagnostic setting of HCC and that exosomal secretion contributes to discharging a subset of microRNAs into the extracellular compartment." circulation_biomarker_diagnosis_ns hsa-mir-519d "Carcinoma, Hepatocellular" 26509672 "Therefore, we show that circulating microRNAs deserve attention as non-invasive biomarkers in the diagnostic setting of HCC and that exosomal secretion contributes to discharging a subset of microRNAs into the extracellular compartment." circulation_biomarker_diagnosis_ns hsa-mir-595 "Carcinoma, Hepatocellular" 26509672 "Therefore, we show that circulating microRNAs deserve attention as non-invasive biomarkers in the diagnostic setting of HCC and that exosomal secretion contributes to discharging a subset of microRNAs into the extracellular compartment." circulation_biomarker_diagnosis_ns hsa-mir-939 "Carcinoma, Hepatocellular" 26509672 "Therefore, we show that circulating microRNAs deserve attention as non-invasive biomarkers in the diagnostic setting of HCC and that exosomal secretion contributes to discharging a subset of microRNAs into the extracellular compartment." circulation_biomarker_diagnosis_ns hsa-mir-21 Gastric Neoplasms 26509997 "In summary, we verified the diagnostic and prognostic value of tissue hsa-miR-21hsa-miR-21 and hsa-miR-29 in GC. Both of them can be potentially applied as novel and non-invasive biomarkers for GC." circulation_biomarker_diagnosis_ns hsa-mir-29 Gastric Neoplasms 26509997 "In summary, we verified the diagnostic and prognostic value of tissue hsa-miR-21hsa-miR-21 and hsa-miR-29 in GC. Both of them can be potentially applied as novel and non-invasive biomarkers for GC." circulation_biomarker_diagnosis_ns hsa-mir-126 Angiosarcoma 26512652 "Our findings suggest that these malignant endothelial proliferative diseases over-secreted miR-214 and miR-126, thus suggesting that these miRNAs have potential as diagnostic biomarkers for malignant endothelial proliferative diseases in canine and possible in human angiosarcoma." circulation_biomarker_diagnosis_ns hsa-mir-214 Angiosarcoma 26512652 "Our findings suggest that these malignant endothelial proliferative diseases over-secreted miR-214 and miR-126, thus suggesting that these miRNAs have potential as diagnostic biomarkers for malignant endothelial proliferative diseases in canine and possible in human angiosarcoma." circulation_biomarker_diagnosis_ns hsa-mir-15a Multiple Myeloma 26516702 "Therefore, our data suggest that the expression patterns of miR-15a/16-1 are different in MM patients, and miR-15a seems to be linked with disease progression and prognosis while miR-16-1 acts as a valuable diagnostic marker." circulation_biomarker_diagnosis_ns hsa-mir-16-1 Multiple Myeloma 26516702 "Therefore, our data suggest that the expression patterns of miR-15a/16-1 are different in MM patients, and miR-15a seems to be linked with disease progression and prognosis while miR-16-1 acts as a valuable diagnostic marker." circulation_biomarker_diagnosis_ns hsa-mir-10b Neoplasms [unspecific] 26522916 Heterogeneity of miR-10b expression in circulating tumor cells. circulation_biomarker_diagnosis_ns hsa-mir-1 Acute Myocardial Infarction 26526403 "In summary, we confirmed the predictive values of plasma miR-1,miR-208 and miR-499 in AMI. In contrast to miR-1, the cardiac-specific miR-208 and miR-499 were supposed to be more reliable as biomarkers in AMI screening and prediction." circulation_biomarker_diagnosis_ns hsa-mir-208 Acute Myocardial Infarction 26526403 "In summary, we confirmed the predictive values of plasma miR-1,miR-208 and miR-499 in AMI. In contrast to miR-1, the cardiac-specific miR-208 and miR-499 were supposed to be more reliable as biomarkers in AMI screening and prediction." circulation_biomarker_diagnosis_ns hsa-mir-499 Acute Myocardial Infarction 26526403 "In summary, we confirmed the predictive values of plasma miR-1,miR-208 and miR-499 in AMI. In contrast to miR-1, the cardiac-specific miR-208 and miR-499 were supposed to be more reliable as biomarkers in AMI screening and prediction." circulation_biomarker_diagnosis_ns hsa-mir-1183 Rheumatic Heart Diseases 26539505 Detection of Differentially Expressed MicroRNAs in Rheumatic Heart Disease:miR-1183 and miR-1299 as Potential Diagnostic Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-1299 Rheumatic Heart Diseases 26539505 Detection of Differentially Expressed MicroRNAs in Rheumatic Heart Disease:miR-1183 and miR-1299 as Potential Diagnostic Biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-499 Acute Myocardial Infarction 26547429 "favorable sensitivity and selectivity,thus provides an alternative for the detection of miRNA. Most importantly, this effort may promote miRNA to work as an effective biomarker in the diagnosis of AMI." circulation_biomarker_diagnosis_ns hsa-mir-10b "Squamous Cell Carcinoma, Esophageal" 26554762 "Predictive Value of Serum miR-10b, miR-29c, and miR-205 as Promising Biomarkers in Esophageal Squamous Cell Carcinoma Screening." circulation_biomarker_diagnosis_ns hsa-mir-205 "Squamous Cell Carcinoma, Esophageal" 26554762 "Predictive Value of Serum miR-10b, miR-29c, and miR-205 as Promising Biomarkers in Esophageal Squamous Cell Carcinoma Screening." circulation_biomarker_diagnosis_ns hsa-mir-29c "Squamous Cell Carcinoma, Esophageal" 26554762 "Predictive Value of Serum miR-10b, miR-29c, and miR-205 as Promising Biomarkers in Esophageal Squamous Cell Carcinoma Screening." circulation_biomarker_diagnosis_ns hsa-mir-320d "Diabetes Mellitus, Type 2" 26554942 This study provided evidence that serum miRNAs had differential expressions between healthy controls and T2DM patients. These five differential expression miRNAs might be of help for subsequent study in T2DM. circulation_biomarker_diagnosis_ns hsa-mir-3960 "Diabetes Mellitus, Type 2" 26554942 This study provided evidence that serum miRNAs had differential expressions between healthy controls and T2DM patients. These five differential expression miRNAs might be of help for subsequent study in T2DM. circulation_biomarker_diagnosis_ns hsa-mir-451a "Diabetes Mellitus, Type 2" 26554942 This study provided evidence that serum miRNAs had differential expressions between healthy controls and T2DM patients. These five differential expression miRNAs might be of help for subsequent study in T2DM. circulation_biomarker_diagnosis_ns hsa-mir-4534 "Diabetes Mellitus, Type 2" 26554942 This study provided evidence that serum miRNAs had differential expressions between healthy controls and T2DM patients. These five differential expression miRNAs might be of help for subsequent study in T2DM. circulation_biomarker_diagnosis_ns hsa-mir-572 "Diabetes Mellitus, Type 2" 26554942 This study provided evidence that serum miRNAs had differential expressions between healthy controls and T2DM patients. These five differential expression miRNAs might be of help for subsequent study in T2DM. circulation_biomarker_diagnosis_ns hsa-mir-146b "Colitis, Ulcerative" 26569605 "This is the first study to show the differential expression of miRNA involving different sites of colon in UC patients. Taking our data and previous reports into consideration, we propose that differential miRNA expression during UC perhaps contribute in the development of UC-associated CRC at the rectosigmoid area." circulation_biomarker_diagnosis_ns hsa-mir-335 "Colitis, Ulcerative" 26569605 "This is the first study to show the differential expression of miRNA involving different sites of colon in UC patients. Taking our data and previous reports into consideration, we propose that differential miRNA expression during UC perhaps contribute in the development of UC-associated CRC at the rectosigmoid area." circulation_biomarker_diagnosis_ns hsa-mir-342 "Colitis, Ulcerative" 26569605 "This is the first study to show the differential expression of miRNA involving different sites of colon in UC patients. Taking our data and previous reports into consideration, we propose that differential miRNA expression during UC perhaps contribute in the development of UC-associated CRC at the rectosigmoid area." circulation_biomarker_diagnosis_ns hsa-mir-4732 "Colitis, Ulcerative" 26569605 "This is the first study to show the differential expression of miRNA involving different sites of colon in UC patients. Taking our data and previous reports into consideration, we propose that differential miRNA expression during UC perhaps contribute in the development of UC-associated CRC at the rectosigmoid area." circulation_biomarker_diagnosis_ns hsa-mir-491 "Colitis, Ulcerative" 26569605 "This is the first study to show the differential expression of miRNA involving different sites of colon in UC patients. Taking our data and previous reports into consideration, we propose that differential miRNA expression during UC perhaps contribute in the development of UC-associated CRC at the rectosigmoid area." circulation_biomarker_diagnosis_ns hsa-mir-644b "Colitis, Ulcerative" 26569605 "This is the first study to show the differential expression of miRNA involving different sites of colon in UC patients. Taking our data and previous reports into consideration, we propose that differential miRNA expression during UC perhaps contribute in the development of UC-associated CRC at the rectosigmoid area." circulation_biomarker_diagnosis_ns hsa-mir-140 Gastric Neoplasms 26607322 "This study revealed a three-miRNA signature as a promising classifier for gastric cancer, and greatly enhances the feasibility of circulating miRNAs as non-invasive diagnostic marker for this disease." circulation_biomarker_diagnosis_ns hsa-mir-18a Gastric Neoplasms 26607322 "This study revealed a three-miRNA signature as a promising classifier for gastric cancer, and greatly enhances the feasibility of circulating miRNAs as non-invasive diagnostic marker for this disease." circulation_biomarker_diagnosis_ns hsa-mir-199a Gastric Neoplasms 26607322 "This study revealed a three-miRNA signature as a promising classifier for gastric cancer, and greatly enhances the feasibility of circulating miRNAs as non-invasive diagnostic marker for this disease." circulation_biomarker_diagnosis_ns hsa-mir-627 Gastric Neoplasms 26607322 "This study revealed a three-miRNA signature as a promising classifier for gastric cancer, and greatly enhances the feasibility of circulating miRNAs as non-invasive diagnostic marker for this disease." circulation_biomarker_diagnosis_ns hsa-mir-629 Gastric Neoplasms 26607322 "This study revealed a three-miRNA signature as a promising classifier for gastric cancer, and greatly enhances the feasibility of circulating miRNAs as non-invasive diagnostic marker for this disease." circulation_biomarker_diagnosis_ns hsa-mir-652 Gastric Neoplasms 26607322 "This study revealed a three-miRNA signature as a promising classifier for gastric cancer, and greatly enhances the feasibility of circulating miRNAs as non-invasive diagnostic marker for this disease." circulation_biomarker_diagnosis_ns hsa-mir-29b Glioma 26620922 miR-29b and VEGFA in blood were significantly different compared with the control group circulation_biomarker_diagnosis_ns hsa-mir-193a "Carcinoma, Lung, Non-Small-Cell" 26629532 This serum miRNA panel holds the potential for diagnosing ethnically diverse NSCLC patients circulation_biomarker_diagnosis_ns hsa-mir-214 "Carcinoma, Lung, Non-Small-Cell" 26629532 This serum miRNA panel holds the potential for diagnosing ethnically diverse NSCLC patients circulation_biomarker_diagnosis_ns hsa-mir-25 "Carcinoma, Lung, Non-Small-Cell" 26629532 This serum miRNA panel holds the potential for diagnosing ethnically diverse NSCLC patients circulation_biomarker_diagnosis_ns hsa-mir-483 "Carcinoma, Lung, Non-Small-Cell" 26629532 This serum miRNA panel holds the potential for diagnosing ethnically diverse NSCLC patients circulation_biomarker_diagnosis_ns hsa-mir-7 "Carcinoma, Lung, Non-Small-Cell" 26629532 This serum miRNA panel holds the potential for diagnosing ethnically diverse NSCLC patients circulation_biomarker_diagnosis_ns hsa-mir-125b "Carcinoma, Hepatocellular" 26637228 "A combination of serum miR-125b, miR-223, miR-27a, and miR-26a as a second-line tests could help detect HCC in AFP (-) subjects." circulation_biomarker_diagnosis_ns hsa-mir-122 Rheumatoid Arthritis 26637811 "In conclusion, this study identified 9-plasma miRNAs signature in Chinese patients with RA which may serve as noninvasive biomarkers for the diagnosis of RA." circulation_biomarker_diagnosis_ns hsa-mir-219-2 Rheumatoid Arthritis 26637811 "In conclusion, this study identified 9-plasma miRNAs signature in Chinese patients with RA which may serve as noninvasive biomarkers for the diagnosis of RA." circulation_biomarker_diagnosis_ns hsa-mir-342 Rheumatoid Arthritis 26637811 "In conclusion, this study identified 9-plasma miRNAs signature in Chinese patients with RA which may serve as noninvasive biomarkers for the diagnosis of RA." circulation_biomarker_diagnosis_ns hsa-mir-3925 Rheumatoid Arthritis 26637811 "In conclusion, this study identified 9-plasma miRNAs signature in Chinese patients with RA which may serve as noninvasive biomarkers for the diagnosis of RA." circulation_biomarker_diagnosis_ns hsa-mir-3926 Rheumatoid Arthritis 26637811 "In conclusion, this study identified 9-plasma miRNAs signature in Chinese patients with RA which may serve as noninvasive biomarkers for the diagnosis of RA." circulation_biomarker_diagnosis_ns hsa-mir-4634 Rheumatoid Arthritis 26637811 "In conclusion, this study identified 9-plasma miRNAs signature in Chinese patients with RA which may serve as noninvasive biomarkers for the diagnosis of RA." circulation_biomarker_diagnosis_ns hsa-mir-4764 Rheumatoid Arthritis 26637811 "In conclusion, this study identified 9-plasma miRNAs signature in Chinese patients with RA which may serve as noninvasive biomarkers for the diagnosis of RA." circulation_biomarker_diagnosis_ns hsa-mir-9 Rheumatoid Arthritis 26637811 "In conclusion, this study identified 9-plasma miRNAs signature in Chinese patients with RA which may serve as noninvasive biomarkers for the diagnosis of RA." circulation_biomarker_diagnosis_ns hsa-mir-16-2 "Carcinoma, Cervical" 26656154 "Serum miRNAs panel (miR-16-2*, miR-195, miR-2861, miR-497) as novel non-invasive biomarkers for detection of cervical cancer." circulation_biomarker_diagnosis_ns hsa-mir-195 "Carcinoma, Cervical" 26656154 "Serum miRNAs panel (miR-16-2*, miR-195, miR-2861, miR-497) as novel non-invasive biomarkers for detection of cervical cancer." circulation_biomarker_diagnosis_ns hsa-mir-2861 "Carcinoma, Cervical" 26656154 "Serum miRNAs panel (miR-16-2*, miR-195, miR-2861, miR-497) as novel non-invasive biomarkers for detection of cervical cancer." circulation_biomarker_diagnosis_ns hsa-mir-497 "Carcinoma, Cervical" 26656154 "Serum miRNAs panel (miR-16-2*, miR-195, miR-2861, miR-497) as novel non-invasive biomarkers for detection of cervical cancer." circulation_biomarker_diagnosis_ns hsa-mir-34 Ewing Sarcoma 26659003 MicroRNA expression profiling may have some potential for prediction of disease progression and survival in Ewing sarcoma. circulation_biomarker_diagnosis_ns hsa-mir-367 Germ Cell Tumor 26671749 A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ-cell tumours. circulation_biomarker_diagnosis_ns hsa-mir-371a Germ Cell Tumor 26671749 A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ-cell tumours. circulation_biomarker_diagnosis_ns hsa-mir-372 Germ Cell Tumor 26671749 A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ-cell tumours. circulation_biomarker_diagnosis_ns hsa-mir-373 Germ Cell Tumor 26671749 A pipeline to quantify serum and cerebrospinal fluid microRNAs for diagnosis and detection of relapse in paediatric malignant germ-cell tumours. circulation_biomarker_diagnosis_ns hsa-mir-20a "Carcinoma, Lung, Non-Small-Cell" 26672767 "Among the top markers that were concordant between both studies we found hsa-miR-20b-5p, hsa-miR-20a-5p, hsa-miR-17-5p, and hsa-miR-106a-5p." circulation_biomarker_diagnosis_ns hsa-mir-31 "Tuberculosis, Pulmonary" 26681217 "Therefore, miR-31 has the potential to be a diagnostic marker in pediatric TB patients." circulation_biomarker_diagnosis_ns hsa-mir-21 Digestive System Neoplasms 26683919 Potential Role of Circulating MiR-21 in the Diagnosis and Prognosis of Digestive System Cancer: A Systematic Review and Meta-Analysis. circulation_biomarker_diagnosis_ns hsa-mir-16 Spondylarthritis 26689798 The most repressed miRNA was miR-16 and is predicted to regulate the expression of activin A receptor circulation_biomarker_diagnosis_ns hsa-mir-21 Gastric Neoplasms 26720919 Two-stage cyclic enzymatic amplification method for ultrasensitive electrochemical assay of microRNA-21 in the blood serum of gastric cancer patients. circulation_biomarker_diagnosis_ns hsa-mir-1246 Breast Neoplasms 26749252 Novel combination of serum microRNA for detecting breast cancer in the early stage. circulation_biomarker_diagnosis_ns hsa-mir-1307 Breast Neoplasms 26749252 Novel combination of serum microRNA for detecting breast cancer in the early stage. circulation_biomarker_diagnosis_ns hsa-mir-4634 Breast Neoplasms 26749252 Novel combination of serum microRNA for detecting breast cancer in the early stage. circulation_biomarker_diagnosis_ns hsa-mir-6861 Breast Neoplasms 26749252 Novel combination of serum microRNA for detecting breast cancer in the early stage. circulation_biomarker_diagnosis_ns hsa-mir-6875 Breast Neoplasms 26749252 Novel combination of serum microRNA for detecting breast cancer in the early stage. circulation_biomarker_diagnosis_ns hsa-mir-126 "Carcinoma, Hepatocellular" 26756996 Hepatic miR-126 is a potential plasma biomarker for detection of hepatitis B virus infected hepatocellular carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-155 Neoplasms [unspecific] 26765436 Appraising MicroRNA-155 as a Noninvasive Diagnostic Biomarker for Cancer Detection: A Meta-Analysis. circulation_biomarker_diagnosis_ns hsa-mir-223 "Carcinoma, Hepatocellular" 26776075 Serum miR-30e and miR-224 as Novel Noninvasive Biomarkers for Hepatocellular Carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-30e "Carcinoma, Hepatocellular" 26776075 Serum miR-30e and miR-223 as Novel Noninvasive Biomarkers for Hepatocellular Carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-196a "Carcinoma, Cervical" 26782446 Clinical significance of serum miR-196a in cervical intraepithelial neoplasia and cervical cancer. circulation_biomarker_diagnosis_ns hsa-mir-132 Stroke 26806865 "These results indicated that there was a substantial correlation between serum miR-132 expression and post-stroke cognitive functionality,suggesting that miR-132 may be a risk marker for PSCI. Because of the limitations of this study, the results should be treated with caution. cel-mir-39" circulation_biomarker_diagnosis_ns hsa-mir-204 Pancreatic Adenocarcinoma 26807325 miR-223 and miR-204 were able to distinguish patients with early stage cancer from patients with CP circulation_biomarker_diagnosis_ns hsa-mir-34b Major Depressive Disorder 26807671 "Differentially Notch-associated miRNAs expressions in peripheral blood might be involved in MDD, and the miR-34b-5p and miR-34c-5p levels in peripheral blood leukocytes are closely related to MDD, suicide idea and cognitive function, further studies with large sample size are warranted to test the feasibility of these miRNAs serving as biomarkers for MDD." circulation_biomarker_diagnosis_ns hsa-mir-34c Major Depressive Disorder 26807671 "Differentially Notch-associated miRNAs expressions in peripheral blood might be involved in MDD, and the miR-34b-5p and miR-34c-5p levels in peripheral blood leukocytes are closely related to MDD, suicide idea and cognitive function, further studies with large sample size are warranted to test the feasibility of these miRNAs serving as biomarkers for MDD." circulation_biomarker_diagnosis_ns hsa-mir-3663 Inherited Hemoglobin Disease 26837891 "Discussion Five of these microRNAs including U101, hsa-miR-4726-5p, hsa-miR7109 5p, hsa-miR3663, and hsa-miR940 had significant changes in expression and volume." circulation_biomarker_diagnosis_ns hsa-mir-4726 Inherited Hemoglobin Disease 26837891 "Discussion Five of these microRNAs including U101, hsa-miR-4726-5p, hsa-miR7109 5p, hsa-miR3663, and hsa-miR940 had significant changes in expression and volume." circulation_biomarker_diagnosis_ns hsa-mir-7109 Inherited Hemoglobin Disease 26837891 "Discussion Five of these microRNAs including U101, hsa-miR-4726-5p, hsa-miR7109 5p, hsa-miR3663, and hsa-miR940 had significant changes in expression and volume." circulation_biomarker_diagnosis_ns hsa-mir-940 Inherited Hemoglobin Disease 26837891 "Discussion Five of these microRNAs including U101, hsa-miR-4726-5p, hsa-miR7109 5p, hsa-miR3663, and hsa-miR940 had significant changes in expression and volume." circulation_biomarker_diagnosis_ns hsa-mir-200c Cholangiocarcinoma 26864161 miR-200c was found to be expressed differentially in PSC versus controls circulation_biomarker_diagnosis_ns hsa-mir-222 Cholangiocarcinoma 26864161 a difference in the expression of miR-222 and miR-483-5p in CC versus PSC circulation_biomarker_diagnosis_ns hsa-mir-21 Acute Myocardial Infarction 26875904 Plasma miR-21 may be a novel biomarker for the diagnosis of AMI. Our study may also provide implications for the development of new biomarkers. circulation_biomarker_diagnosis_ns hsa-mir-132 Alzheimer Disease 26899870 Dysregulation of miRNA isoform level at 5' end in Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-136 Alzheimer Disease 26899870 Dysregulation of miRNA isoform level at 5' end in Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-137 Alzheimer Disease 26899870 Dysregulation of miRNA isoform level at 5' end in Alzheimer's disease. circulation_biomarker_diagnosis_ns hsa-mir-103 Myotonic Dystrophy Type 1 26919350 "a selection of six candidate miRNAs, miR-103, miR-107, miR-21, miR-29a, miR-30c, and miR-652 all failed to show consistent differences in serum expression in subsequent validation experiments." circulation_biomarker_diagnosis_ns hsa-mir-107 Myotonic Dystrophy Type 1 26919350 "a selection of six candidate miRNAs, miR-103, miR-107, miR-21, miR-29a, miR-30c, and miR-652 all failed to show consistent differences in serum expression in subsequent validation experiments." circulation_biomarker_diagnosis_ns hsa-mir-107 Hirschsprung Disease 26933947 miRNA Profiling Reveals Dysregulation of RET and RET-Regulating Pathways in Hirschsprung's Disease. circulation_biomarker_diagnosis_ns hsa-mir-142 Hirschsprung Disease 26933947 miRNA Profiling Reveals Dysregulation of RET and RET-Regulating Pathways in Hirschsprung's Disease. circulation_biomarker_diagnosis_ns hsa-mir-146b Hirschsprung Disease 26933947 miRNA Profiling Reveals Dysregulation of RET and RET-Regulating Pathways in Hirschsprung's Disease. circulation_biomarker_diagnosis_ns hsa-mir-369 Hirschsprung Disease 26933947 miRNA Profiling Reveals Dysregulation of RET and RET-Regulating Pathways in Hirschsprung's Disease. circulation_biomarker_diagnosis_ns hsa-mir-429 Hirschsprung Disease 26933947 miRNA Profiling Reveals Dysregulation of RET and RET-Regulating Pathways in Hirschsprung's Disease. circulation_biomarker_diagnosis_ns hsa-mir-638 Hirschsprung Disease 26933947 miRNA Profiling Reveals Dysregulation of RET and RET-Regulating Pathways in Hirschsprung's Disease. circulation_biomarker_diagnosis_ns hsa-mir-885 Hirschsprung Disease 26933947 miRNA Profiling Reveals Dysregulation of RET and RET-Regulating Pathways in Hirschsprung's Disease. circulation_biomarker_diagnosis_ns hsa-mir-938 Hirschsprung Disease 26933947 miRNA Profiling Reveals Dysregulation of RET and RET-Regulating Pathways in Hirschsprung's Disease. circulation_biomarker_diagnosis_ns hsa-mir-133a Hypertension 26984682 miRNA-208b and miRNA-133a show distinct profiling in peripheral blood cells isolated from untreated patients circulation_biomarker_diagnosis_ns hsa-mir-208b Hypertension 26984682 miRNA-208b and miRNA-133a show distinct profiling in peripheral blood cells isolated from untreated patients circulation_biomarker_diagnosis_ns hsa-mir-26a Gastric Neoplasms 27010210 Circulating MicroRNA-26a in Plasma and Its Potential Diagnostic Value in Gastric Cancer. circulation_biomarker_diagnosis_ns hsa-mir-146a Autoimmune Lymphoproliferative Syndrome 27060458 "miR-21-3p was over-expressed significantly (P = 0·0313) in the son, with no significant change in the expression of miR-146a, miR-146a-3p and miR-21." circulation_biomarker_diagnosis_ns hsa-mir-130a "Carcinoma, Ovarian" 27062783 Expression of MiR-130a in Serum Samples of Patients with Epithelial Ovarian Cancer and Its Association with Platinum Resistance. circulation_biomarker_diagnosis_ns hsa-mir-144 Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-16 Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-184 Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-19a Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-202 Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-205 Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-22 Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-24 Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-29a Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-29c Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-3074 Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-30a Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-30d Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-4448 Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-451a Glaucoma 27064390 "Our data illustrate the feasibility of miRNA analysis by NGS in small individual aqueous humor samples. Intraocular cells as well as blood plasma contribute to the extracellular aqueous humor miRNome. The data suggest possible roles of miRNA in intraocular cell adhesion and signaling by TGF-¦Â and Wnt, which are important in intraocular pressure regulation and glaucoma." circulation_biomarker_diagnosis_ns hsa-mir-122 "Fatty Liver, Non-Alcoholic" 27077736 Association of Circulating Serum miR-34a and miR-122 with Dyslipidemia among Patients with Non-Alcoholic Fatty Liver Disease. circulation_biomarker_diagnosis_ns hsa-mir-34a "Fatty Liver, Non-Alcoholic" 27077736 Association of Circulating Serum miR-34a and miR-122 with Dyslipidemia among Patients with Non-Alcoholic Fatty Liver Disease. circulation_biomarker_diagnosis_ns hsa-mir-125b "Carcinoma, Ovarian" 27092777 Utility of Serum miR-125b as a Diagnostic and Prognostic Indicator and Its Alliance with a Panel of Tumor Suppressor Genes in Epithelial Ovarian Cancer. circulation_biomarker_diagnosis_ns hsa-mir-126 Early-Stage Non-Small-Cell Lung Carcinoma 27093275 "Diagnostic Value of Serum miR-182, miR-183, miR-210, and miR-126 Levels in Patients with Early-Stage Non-Small Cell Lung Cancer." circulation_biomarker_diagnosis_ns hsa-mir-182 Early-Stage Non-Small-Cell Lung Carcinoma 27093275 "Diagnostic Value of Serum miR-182, miR-183, miR-210, and miR-126 Levels in Patients with Early-Stage Non-Small Cell Lung Cancer." circulation_biomarker_diagnosis_ns hsa-mir-183 Early-Stage Non-Small-Cell Lung Carcinoma 27093275 "Diagnostic Value of Serum miR-182, miR-183, miR-210, and miR-126 Levels in Patients with Early-Stage Non-Small Cell Lung Cancer." circulation_biomarker_diagnosis_ns hsa-mir-210 Early-Stage Non-Small-Cell Lung Carcinoma 27093275 "Diagnostic Value of Serum miR-182, miR-183, miR-210, and miR-126 Levels in Patients with Early-Stage Non-Small Cell Lung Cancer." circulation_biomarker_diagnosis_ns hsa-mir-372 "Carcinoma, Lung, Non-Small-Cell" 27122989 "A sputum mir-21, mir-210, and mir-372 expression profile might provide a sensitive and highly specific means for detecting nsclc." circulation_biomarker_diagnosis_ns hsa-mir-122 "Stroke, Ischemic" 27151415 Two miRNAs (miR-145 and miR-122) may represent potential biomarkers in ischemic stroke circulation_biomarker_diagnosis_ns hsa-let-7g Myocardial Infarction 27192016 we identified several miRs associated with future AMI circulation_biomarker_diagnosis_ns hsa-mir-106a Myocardial Infarction 27192016 we identified several miRs associated with future AMI circulation_biomarker_diagnosis_ns hsa-mir-144 Myocardial Infarction 27192016 we identified several miRs associated with future AMI circulation_biomarker_diagnosis_ns hsa-mir-26a Myocardial Infarction 27192016 miR-424-5p and miR-26a-5p were associated exclusively with risk in men and women circulation_biomarker_diagnosis_ns hsa-mir-424 Myocardial Infarction 27192016 we identified several miRs associated with future AMI circulation_biomarker_diagnosis_ns hsa-mir-660 Myocardial Infarction 27192016 we identified several miRs associated with future AMI circulation_biomarker_diagnosis_ns hsa-mir-122 Hepatitis C Virus Infection 27239848 Evaluation of miR-122 level in the plasma of chronically HCV infected patients. circulation_biomarker_diagnosis_ns hsa-mir-122 Idiopathic Asthenospermia 27264812 Seminal plasma miR-122-3p and miR-141-5p stability and its diagnosis value for idiopathic asthenospermia. circulation_biomarker_diagnosis_ns hsa-mir-141 Idiopathic Asthenospermia 27264812 Seminal plasma miR-122-3p and miR-141-5p stability and its diagnosis value for idiopathic asthenospermia. circulation_biomarker_diagnosis_ns hsa-mir-122 "Carcinoma, Hepatocellular" 27271989 "Using miRNA panel of miR-122, miR-885-5p, and miR-29b with alpha fetoprotein (AFP) provided high diagnostic accuracy" circulation_biomarker_diagnosis_ns hsa-mir-199a "Carcinoma, Hepatocellular" 27271989 using miRNA panel of miR-22 and miR-199a-3p with AFP provided high diagnostic accuracy circulation_biomarker_diagnosis_ns hsa-mir-22 "Carcinoma, Hepatocellular" 27271989 using miRNA panel of miR-22 and miR-199a-3p with AFP provided high diagnostic accuracy circulation_biomarker_diagnosis_ns hsa-mir-221 "Carcinoma, Hepatocellular" 27271989 "using miRNA panel of miR-122, miR-885-5p, miR-221, and miR-22 with AFP provided high diagnostic accuracy" circulation_biomarker_diagnosis_ns hsa-mir-29b "Carcinoma, Hepatocellular" 27271989 "Using miRNA panel of miR-122, miR-885-5p, and miR-29b with alpha fetoprotein (AFP) provided high diagnostic accuracy" circulation_biomarker_diagnosis_ns hsa-mir-885 "Carcinoma, Hepatocellular" 27271989 "Using miRNA panel of miR-122, miR-885-5p, and miR-29b with alpha fetoprotein (AFP) provided high diagnostic accuracy" circulation_biomarker_diagnosis_ns hsa-mir-21 Breast Neoplasms 27311114 MicroRNA-21 (miR-21) is a promising diagnostic biomarker for breast cancer screening and disease progression circulation_biomarker_diagnosis_ns hsa-mir-132 Spinal Muscular Atrophy 27377135 confirmed a significant alteration of miR-9 and miR-132 level in serum samples from SMA patients. circulation_biomarker_diagnosis_ns hsa-mir-193b Pancreatic Neoplasms 27380024 "Patients with PDAC or IPMN showed significantly higher amounts of serum MAPK-associated miRNAs than those with AIP (p<0.009 for miR-7, p<0.002 for miR-34a, p<0.001 for miR-181d, p<0.002 for miR-193b)." circulation_biomarker_diagnosis_ns hsa-mir-34a Pancreatic Neoplasms 27380024 "Patients with PDAC or IPMN showed significantly higher amounts of serum MAPK-associated miRNAs than those with AIP (p<0.009 for miR-7, p<0.002 for miR-34a, p<0.001 for miR-181d, p<0.002 for miR-193b)." circulation_biomarker_diagnosis_ns hsa-mir-7 Pancreatic Neoplasms 27380024 "Patients with PDAC or IPMN showed significantly higher amounts of serum MAPK-associated miRNAs than those with AIP (p<0.009 for miR-7, p<0.002 for miR-34a, p<0.001 for miR-181d, p<0.002 for miR-193b)." circulation_biomarker_diagnosis_ns hsa-mir-122 Sepsis 27434572 "The researches regarding circulating miRNA as biomarkers of sepsis were collected to analyze the characteristics of differential expression of miRNAs including miR-150, miR-133a, miR-122, miR-223, miR-4772, miR-297 and miR-574-5p etc." circulation_biomarker_diagnosis_ns hsa-mir-133a Sepsis 27434572 "The researches regarding circulating miRNA as biomarkers of sepsis were collected to analyze the characteristics of differential expression of miRNAs including miR-150, miR-133a, miR-122, miR-223, miR-4772, miR-297 and miR-574-5p etc." circulation_biomarker_diagnosis_ns hsa-mir-150 Sepsis 27434572 "The researches regarding circulating miRNA as biomarkers of sepsis were collected to analyze the characteristics of differential expression of miRNAs including miR-150, miR-133a, miR-122, miR-223, miR-4772, miR-297 and miR-574-5p etc." circulation_biomarker_diagnosis_ns hsa-mir-223 Sepsis 27434572 "The researches regarding circulating miRNA as biomarkers of sepsis were collected to analyze the characteristics of differential expression of miRNAs including miR-150, miR-133a, miR-122, miR-223, miR-4772, miR-297 and miR-574-5p etc." circulation_biomarker_diagnosis_ns hsa-mir-297 Sepsis 27434572 "The researches regarding circulating miRNA as biomarkers of sepsis were collected to analyze the characteristics of differential expression of miRNAs including miR-150, miR-133a, miR-122, miR-223, miR-4772, miR-297 and miR-574-5p etc." circulation_biomarker_diagnosis_ns hsa-mir-4772 Sepsis 27434572 "The researches regarding circulating miRNA as biomarkers of sepsis were collected to analyze the characteristics of differential expression of miRNAs including miR-150, miR-133a, miR-122, miR-223, miR-4772, miR-297 and miR-574-5p etc." circulation_biomarker_diagnosis_ns hsa-mir-574 Sepsis 27434572 "The researches regarding circulating miRNA as biomarkers of sepsis were collected to analyze the characteristics of differential expression of miRNAs including miR-150, miR-133a, miR-122, miR-223, miR-4772, miR-297 and miR-574-5p etc." circulation_biomarker_diagnosis_ns hsa-mir-16 "Carcinoma, Pancreatic" 27464352 "We found that 34 miRNAs in serum from PC patients in the discovery cohort were expressed differently than in controls. These miRNAs were tested in the training cohort, and four diagnostic panels were constructed that included 5 or 12 miRNAs (miR-16, -18a, -20a, -24, -25, -27a, -29c, -30a.5p, -191, -323.3p, -345 and -483.5p)." circulation_biomarker_diagnosis_ns hsa-mir-18a "Carcinoma, Pancreatic" 27464352 "We found that 34 miRNAs in serum from PC patients in the discovery cohort were expressed differently than in controls. These miRNAs were tested in the training cohort, and four diagnostic panels were constructed that included 5 or 12 miRNAs (miR-16, -18a, -20a, -24, -25, -27a, -29c, -30a.5p, -191, -323.3p, -345 and -483.5p)." circulation_biomarker_diagnosis_ns hsa-mir-191 "Carcinoma, Pancreatic" 27464352 "We found that 34 miRNAs in serum from PC patients in the discovery cohort were expressed differently than in controls. These miRNAs were tested in the training cohort, and four diagnostic panels were constructed that included 5 or 12 miRNAs (miR-16, -18a, -20a, -24, -25, -27a, -29c, -30a.5p, -191, -323.3p, -345 and -483.5p)." circulation_biomarker_diagnosis_ns hsa-mir-20a "Carcinoma, Pancreatic" 27464352 "We found that 34 miRNAs in serum from PC patients in the discovery cohort were expressed differently than in controls. These miRNAs were tested in the training cohort, and four diagnostic panels were constructed that included 5 or 12 miRNAs (miR-16, -18a, -20a, -24, -25, -27a, -29c, -30a.5p, -191, -323.3p, -345 and -483.5p)." circulation_biomarker_diagnosis_ns hsa-mir-24 "Carcinoma, Pancreatic" 27464352 "We found that 34 miRNAs in serum from PC patients in the discovery cohort were expressed differently than in controls. These miRNAs were tested in the training cohort, and four diagnostic panels were constructed that included 5 or 12 miRNAs (miR-16, -18a, -20a, -24, -25, -27a, -29c, -30a.5p, -191, -323.3p, -345 and -483.5p)." circulation_biomarker_diagnosis_ns hsa-mir-25 "Carcinoma, Pancreatic" 27464352 "We found that 34 miRNAs in serum from PC patients in the discovery cohort were expressed differently than in controls. These miRNAs were tested in the training cohort, and four diagnostic panels were constructed that included 5 or 12 miRNAs (miR-16, -18a, -20a, -24, -25, -27a, -29c, -30a.5p, -191, -323.3p, -345 and -483.5p)." circulation_biomarker_diagnosis_ns hsa-mir-27a "Carcinoma, Pancreatic" 27464352 "We found that 34 miRNAs in serum from PC patients in the discovery cohort were expressed differently than in controls. These miRNAs were tested in the training cohort, and four diagnostic panels were constructed that included 5 or 12 miRNAs (miR-16, -18a, -20a, -24, -25, -27a, -29c, -30a.5p, -191, -323.3p, -345 and -483.5p)." circulation_biomarker_diagnosis_ns hsa-mir-29c "Carcinoma, Pancreatic" 27464352 "We found that 34 miRNAs in serum from PC patients in the discovery cohort were expressed differently than in controls. These miRNAs were tested in the training cohort, and four diagnostic panels were constructed that included 5 or 12 miRNAs (miR-16, -18a, -20a, -24, -25, -27a, -29c, -30a.5p, -191, -323.3p, -345 and -483.5p)." circulation_biomarker_diagnosis_ns hsa-mir-30a "Carcinoma, Pancreatic" 27464352 "We found that 34 miRNAs in serum from PC patients in the discovery cohort were expressed differently than in controls. These miRNAs were tested in the training cohort, and four diagnostic panels were constructed that included 5 or 12 miRNAs (miR-16, -18a, -20a, -24, -25, -27a, -29c, -30a.5p, -191, -323.3p, -345 and -483.5p)." circulation_biomarker_diagnosis_ns hsa-mir-323 "Carcinoma, Pancreatic" 27464352 "We found that 34 miRNAs in serum from PC patients in the discovery cohort were expressed differently than in controls. These miRNAs were tested in the training cohort, and four diagnostic panels were constructed that included 5 or 12 miRNAs (miR-16, -18a, -20a, -24, -25, -27a, -29c, -30a.5p, -191, -323.3p, -345 and -483.5p)." circulation_biomarker_diagnosis_ns hsa-mir-345 "Carcinoma, Pancreatic" 27464352 "We found that 34 miRNAs in serum from PC patients in the discovery cohort were expressed differently than in controls. These miRNAs were tested in the training cohort, and four diagnostic panels were constructed that included 5 or 12 miRNAs (miR-16, -18a, -20a, -24, -25, -27a, -29c, -30a.5p, -191, -323.3p, -345 and -483.5p)." circulation_biomarker_diagnosis_ns hsa-mir-483 "Carcinoma, Pancreatic" 27464352 "We found that 34 miRNAs in serum from PC patients in the discovery cohort were expressed differently than in controls. These miRNAs were tested in the training cohort, and four diagnostic panels were constructed that included 5 or 12 miRNAs (miR-16, -18a, -20a, -24, -25, -27a, -29c, -30a.5p, -191, -323.3p, -345 and -483.5p)." circulation_biomarker_diagnosis_ns hsa-mir-148b "Carcinoma, Thyroid, Follicular" 27473101 The best two-miRNA classifier (miR-484/miR-148b-3p) identified thyroid malignancy with a sensitivity of 89â€? and a specificity of 87â€?. circulation_biomarker_diagnosis_ns hsa-mir-142 "Carcinoma, Colon" 27485599 "diagnostic four-microRNA signature consisting of miR-23a-3p, miR-27a-3p, miR-142-5p and miR-376c-3p was established (AUC = 0.917), distinguishing colon cancer patients from healthy donors." circulation_biomarker_diagnosis_ns hsa-mir-23a "Carcinoma, Colon" 27485599 "A diagnostic four-microRNA signature consisting of miR-23a-3p, miR-27a-3p, miR-142-5p and miR-376c-3p was established (AUC = 0.917), distinguishing colon cancer patients from healthy donors with sensitivity of 89% and specificity of 81% (AUC = 0.922)." circulation_biomarker_diagnosis_ns hsa-mir-27a "Carcinoma, Colon" 27485599 "A diagnostic four-microRNA signature consisting of miR-23a-3p, miR-27a-3p, miR-142-5p and miR-376c-3p was established (AUC = 0.917), distinguishing colon cancer patients from healthy donors with sensitivity of 89% and specificity of 81% (AUC = 0.922)." circulation_biomarker_diagnosis_ns hsa-mir-376c "Carcinoma, Colon" 27485599 "A diagnostic four-microRNA signature consisting of miR-23a-3p, miR-27a-3p, miR-142-5p and miR-376c-3p was established (AUC = 0.917), distinguishing colon cancer patients from healthy donors with sensitivity of 89% and specificity of 81% (AUC = 0.922)." circulation_biomarker_diagnosis_ns hsa-mir-206 Muscular Dystrophy 27529242 "miR-206 has potential as a ""liquid biopsy"" for carrier detection and genetic counseling in DMD." circulation_biomarker_diagnosis_ns hsa-mir-221 Pancreatic Neoplasms 27539232 "Circulating microRNAs as Potential Diagnostic, Prognostic and Therapeutic Targets in Pancreatic Cancer." circulation_biomarker_diagnosis_ns hsa-mir-96 Pancreatic Neoplasms 27539232 "Circulating microRNAs as Potential Diagnostic, Prognostic and Therapeutic Targets in Pancreatic Cancer." circulation_biomarker_diagnosis_ns hsa-mir-26b Graft-Versus-Host Disease 27553380 The predictive value of selected serum microRNAs for acute GVHD by TaqMan MicroRNA arrays. circulation_biomarker_diagnosis_ns hsa-mir-28 Graft-Versus-Host Disease 27553380 The predictive value of selected serum microRNAs for acute GVHD by TaqMan MicroRNA arrays. circulation_biomarker_diagnosis_ns hsa-mir-374a Graft-Versus-Host Disease 27553380 The predictive value of selected serum microRNAs for acute GVHD by TaqMan MicroRNA arrays. circulation_biomarker_diagnosis_ns hsa-mir-411 Graft-Versus-Host Disease 27553380 The predictive value of selected serum microRNAs for acute GVHD by TaqMan MicroRNA arrays. circulation_biomarker_diagnosis_ns hsa-mir-489 Graft-Versus-Host Disease 27553380 The predictive value of selected serum microRNAs for acute GVHD by TaqMan MicroRNA arrays. circulation_biomarker_diagnosis_ns hsa-mir-671 Graft-Versus-Host Disease 27553380 The predictive value of selected serum microRNAs for acute GVHD by TaqMan MicroRNA arrays. circulation_biomarker_diagnosis_ns hsa-mir-23a "Squamous Cell Carcinoma, Esophageal" 27566562 Plasma microRNA profiles: identification of miR-23a as a novel biomarker for chemoresistance in esophageal squamous cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-21 Acute Coronary Syndrome 27590242 The role of serum levels of microRNA-21 and matrix metalloproteinase-9 in patients with acute coronary syndrome. circulation_biomarker_diagnosis_ns hsa-mir-122 Acute Myocardial Infarction 27593229 Circulating miR-122-5p/miR-133b Ratio Is a Specific Early Prognostic Biomarker in Acute Myocardial Infarction. circulation_biomarker_diagnosis_ns hsa-mir-133b Acute Myocardial Infarction 27593229 Circulating miR-122-5p/miR-133b Ratio Is a Specific Early Prognostic Biomarker in Acute Myocardial Infarction. circulation_biomarker_diagnosis_ns hsa-mir-21 Hepatoblastoma 27601233 Diagnostic and prognostic values of serum exosomal microRNA-21 in children with hepatoblastoma: a Chinese population-based study. circulation_biomarker_diagnosis_ns hsa-mir-208a Coronary Artery Disease 27602213 Analysis of plasma miR-208a and miR-370 expression levels for early diagnosis of coronary artery disease. circulation_biomarker_diagnosis_ns hsa-mir-370 Coronary Artery Disease 27602213 Analysis of plasma miR-208a and miR-370 expression levels for early diagnosis of coronary artery disease. circulation_biomarker_diagnosis_ns hsa-mir-27a Multiple Sclerosis 27606352 Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis. circulation_biomarker_diagnosis_ns hsa-mir-206 "Carcinoma, Gastric" 27614739 Diagnostic and Prognostic Value of Serum MicroRNA-206 in Patients with Gastric Cancer. circulation_biomarker_diagnosis_ns hsa-mir-22 "Carcinoma, Pancreatic" 27631726 "Plasma miR-22-3p, miR-642b-3p and miR-885-5p as diagnostic biomarkers for pancreatic cancer." circulation_biomarker_diagnosis_ns hsa-mir-642b "Carcinoma, Pancreatic" 27631726 "Plasma miR-22-3p, miR-642b-3p and miR-885-5p as diagnostic biomarkers for pancreatic cancer." circulation_biomarker_diagnosis_ns hsa-mir-885 "Carcinoma, Pancreatic" 27631726 "Plasma miR-22-3p, miR-642b-3p and miR-885-5p as diagnostic biomarkers for pancreatic cancer." circulation_biomarker_diagnosis_ns hsa-mir-122 Colorectal Carcinoma 27632639 Plasma miR-122 and miR-200 family are prognostic markers in colorectal cancer. circulation_biomarker_diagnosis_ns hsa-mir-200 Colorectal Carcinoma 27632639 Plasma miR-122 and miR-200 family are prognostic markers in colorectal cancer. circulation_biomarker_diagnosis_ns hsa-mir-139 "Carcinoma, Hepatocellular" 27633066 Reanalysis of microRNA expression profiles identifies novel biomarkers for hepatocellular carcinoma prognosis. circulation_biomarker_diagnosis_ns hsa-let-7f Liver Diseases [unspecific] 27639178 Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood. circulation_biomarker_diagnosis_ns hsa-mir-29a Liver Diseases [unspecific] 27639178 Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood. circulation_biomarker_diagnosis_ns hsa-mir-340 Liver Diseases [unspecific] 27639178 Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood. circulation_biomarker_diagnosis_ns hsa-mir-25 "Carcinoma, Pancreatic" 27639768 Identification of Circulating MiR-25 as a Potential Biomarker for Pancreatic Cancer Diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-1 Aplastic Anemia 27658437 A plasma microRNA signature as a biomarker for acquired aplastic anemia. circulation_biomarker_diagnosis_ns hsa-mir-146b Aplastic Anemia 27658437 A plasma microRNA signature as a biomarker for acquired aplastic anemia. circulation_biomarker_diagnosis_ns hsa-mir-150 Aplastic Anemia 27658437 A plasma microRNA signature as a biomarker for acquired aplastic anemia. circulation_biomarker_diagnosis_ns hsa-mir-125b Age-Related Macular Degeneration 27658786 "mir-17, miR-125b and miR-155 were dysregulated in multiple AMD mouse models as well as in human AMD plasma or retinae" circulation_biomarker_diagnosis_ns hsa-mir-155 Age-Related Macular Degeneration 27658786 "mir-17, miR-125b and miR-155 were dysregulated in multiple AMD mouse models as well as in human AMD plasma or retinae" circulation_biomarker_diagnosis_ns hsa-mir-17 Age-Related Macular Degeneration 27658786 "mir-17, miR-125b and miR-155 were dysregulated in multiple AMD mouse models as well as in human AMD plasma or retinae" circulation_biomarker_diagnosis_ns hsa-mir-33a Atherosclerosis 27664032 Aberrant expression of plasma microRNA-33a in an atherosclerosis-risk group. circulation_biomarker_diagnosis_ns hsa-let-7g "Tuberculosis, Pulmonary" 27682490 The expression of serum miRNAs in pneumoconiosis complicated with pulmonary tuberculosis patients. circulation_biomarker_diagnosis_ns hsa-mir-155 "Tuberculosis, Pulmonary" 27682490 The expression of serum miRNAs in pneumoconiosis complicated with pulmonary tuberculosis patients. circulation_biomarker_diagnosis_ns hsa-mir-16 "Tuberculosis, Pulmonary" 27682490 The expression of serum miRNAs in pneumoconiosis complicated with pulmonary tuberculosis patients. circulation_biomarker_diagnosis_ns hsa-mir-192 "Tuberculosis, Pulmonary" 27682490 The expression of serum miRNAs in pneumoconiosis complicated with pulmonary tuberculosis patients. circulation_biomarker_diagnosis_ns hsa-mir-200c "Tuberculosis, Pulmonary" 27682490 The expression of serum miRNAs in pneumoconiosis complicated with pulmonary tuberculosis patients. circulation_biomarker_diagnosis_ns hsa-mir-204 "Tuberculosis, Pulmonary" 27682490 The expression of serum miRNAs in pneumoconiosis complicated with pulmonary tuberculosis patients. circulation_biomarker_diagnosis_ns hsa-mir-206 "Tuberculosis, Pulmonary" 27682490 The expression of serum miRNAs in pneumoconiosis complicated with pulmonary tuberculosis patients. circulation_biomarker_diagnosis_ns hsa-mir-21 "Tuberculosis, Pulmonary" 27682490 The expression of serum miRNAs in pneumoconiosis complicated with pulmonary tuberculosis patients. circulation_biomarker_diagnosis_ns hsa-mir-29a "Tuberculosis, Pulmonary" 27682490 The expression of serum miRNAs in pneumoconiosis complicated with pulmonary tuberculosis patients. circulation_biomarker_diagnosis_ns hsa-mir-30b "Tuberculosis, Pulmonary" 27682490 The expression of serum miRNAs in pneumoconiosis complicated with pulmonary tuberculosis patients. circulation_biomarker_diagnosis_ns hsa-mir-21 Cholangiocarcinoma 27685844 Circulating Plasma Levels of MicroRNA-21 and MicroRNA-221 Are Potential Diagnostic Markers for Primary Intrahepatic Cholangiocarcinoma. circulation_biomarker_diagnosis_ns hsa-mir-221 Cholangiocarcinoma 27685844 Circulating Plasma Levels of MicroRNA-21 and MicroRNA-221 Are Potential Diagnostic Markers for Primary Intrahepatic Cholangiocarcinoma. circulation_biomarker_diagnosis_ns hsa-mir-23a Cardiovascular Diseases [unspecific] 27725938 Optimized Collection Protocol for Plasma MicroRNA Measurement in Patients with Cardiovascular Disease. circulation_biomarker_diagnosis_ns hsa-mir-451a Cardiovascular Diseases [unspecific] 27725938 Optimized Collection Protocol for Plasma MicroRNA Measurement in Patients with Cardiovascular Disease. circulation_biomarker_diagnosis_ns hsa-mir-150 "Leukemia, Lymphocytic, Chronic, B-Cell" 27730344 Expression of circulating miRNAs associated with lymphocyte differentiation and activation in CLL-another piece in the puzzle. circulation_biomarker_diagnosis_ns hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 27730344 Expression of circulating miRNAs associated with lymphocyte differentiation and activation in CLL-another piece in the puzzle. circulation_biomarker_diagnosis_ns hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 27730344 Expression of circulating miRNAs associated with lymphocyte differentiation and activation in CLL-another piece in the puzzle. circulation_biomarker_diagnosis_ns hsa-mir-29a "Leukemia, Lymphocytic, Chronic, B-Cell" 27730344 Expression of circulating miRNAs associated with lymphocyte differentiation and activation in CLL-another piece in the puzzle. circulation_biomarker_diagnosis_ns hsa-mir-31 "Leukemia, Lymphocytic, Chronic, B-Cell" 27730344 Expression of circulating miRNAs associated with lymphocyte differentiation and activation in CLL-another piece in the puzzle. circulation_biomarker_diagnosis_ns hsa-mir-34a "Leukemia, Lymphocytic, Chronic, B-Cell" 27730344 Expression of circulating miRNAs associated with lymphocyte differentiation and activation in CLL-another piece in the puzzle. circulation_biomarker_diagnosis_ns hsa-mir-195 "Carcinoma, Lung, Non-Small-Cell" 27733164 Diagnostic and prognostic value of plasma microRNA-195 in patients with non-small cell lung cancer. circulation_biomarker_diagnosis_ns hsa-mir-497 Osteosarcoma 27735043 miR-497 as a potential serum biomarker for the diagnosis and prognosis of osteosarcoma. circulation_biomarker_diagnosis_ns hsa-mir-221 Parkinson Disease 27748571 Serum miR-221 serves as a biomarker for Parkinson's disease. circulation_biomarker_diagnosis_ns hsa-mir-155 "Carcinoma, Hepatocellular" 27751368 Relationship Between Serum microRNA155 and Telomerase Expression in Hepatocellular Carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-146a Ischemia-Reperfusion Injury 27760486 Micro RNA-320 as a novel potential biomarker in renal ischemia reperfusion. circulation_biomarker_diagnosis_ns hsa-mir-155 Hematologic Neoplasms 27761889 "EV miR155 may serve as an attractive new, non-invasive diagnostic biomarker in human hematologic malignancies" circulation_biomarker_diagnosis_ns hsa-mir-183 "Carcinoma, Lung" 27768748 Plasma miR-19b and miR-183 as Potential Biomarkers of Lung Cancer. circulation_biomarker_diagnosis_ns hsa-mir-19b "Carcinoma, Lung" 27768748 Plasma miR-19b and miR-183 as Potential Biomarkers of Lung Cancer. circulation_biomarker_diagnosis_ns hsa-let-7e "Stroke, Ischemic" 27776139 Identification of Blood Let-7e-5p as a Biomarker for Ischemic Stroke. circulation_biomarker_diagnosis_ns hsa-mir-21 Atherosclerosis 27785570 "Association of serum microRNA-21 levels with Visfatin, inflammation, and acute coronary syndromes." circulation_biomarker_diagnosis_ns hsa-mir-150 "Carcinoma, Colon" 27798914 "miR-21, miR-221 and miR-150 Are Deregulated in Peripheral Blood of Patients with Colorectal Cancer." circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Colon" 27798914 "miR-21, miR-221 and miR-150 Are Deregulated in Peripheral Blood of Patients with Colorectal Cancer." circulation_biomarker_diagnosis_ns hsa-mir-221 "Carcinoma, Colon" 27798914 "miR-21, miR-221 and miR-150 Are Deregulated in Peripheral Blood of Patients with Colorectal Cancer." circulation_biomarker_diagnosis_ns hsa-mir-15a "Squamous Cell Carcinoma, Esophageal" 27802201 Serum microRNA-15a level acts as a potential diagnostic and prognostic biomarker for human esophageal squamous cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-106a "Carcinoma, Renal Cell" 27814278 Functional analysis of serum microRNAs miR-21 and miR-106a in renal cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Renal Cell" 27814278 Functional analysis of serum microRNAs miR-21 and miR-106a in renal cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-181a Systemic Lupus Erythematosus 27816459 "MicroRNA-21, microRNA-181a and microRNA-196a as potential biomarkers in adult Egyptian patients with systemic lupus erythematosus." circulation_biomarker_diagnosis_ns hsa-mir-196a Systemic Lupus Erythematosus 27816459 "MicroRNA-21, microRNA-181a and microRNA-196a as potential biomarkers in adult Egyptian patients with systemic lupus erythematosus." circulation_biomarker_diagnosis_ns hsa-mir-21 Systemic Lupus Erythematosus 27816459 "MicroRNA-21, microRNA-181a and microRNA-196a as potential biomarkers in adult Egyptian patients with systemic lupus erythematosus." circulation_biomarker_diagnosis_ns hsa-mir-143 Mesial Temporal Lobe Epilepsy 27833019 Changes in serum miRNAs following generalized convulsive seizures in human mesial temporal lobe epilepsy. circulation_biomarker_diagnosis_ns hsa-mir-145 Mesial Temporal Lobe Epilepsy 27833019 Changes in serum miRNAs following generalized convulsive seizures in human mesial temporal lobe epilepsy. circulation_biomarker_diagnosis_ns hsa-mir-365a Mesial Temporal Lobe Epilepsy 27833019 Changes in serum miRNAs following generalized convulsive seizures in human mesial temporal lobe epilepsy. circulation_biomarker_diagnosis_ns hsa-mir-532 Mesial Temporal Lobe Epilepsy 27833019 Changes in serum miRNAs following generalized convulsive seizures in human mesial temporal lobe epilepsy. circulation_biomarker_diagnosis_ns hsa-mir-663b Mesial Temporal Lobe Epilepsy 27833019 Changes in serum miRNAs following generalized convulsive seizures in human mesial temporal lobe epilepsy. circulation_biomarker_diagnosis_ns hsa-mir-221 Systemic Lupus Erythematosus 27835701 High-Throughput Sequencing Reveals Circulating miRNAs as Potential Biomarkers of Kidney Damage in Patients with Systemic Lupus Erythematosus. circulation_biomarker_diagnosis_ns hsa-mir-3074 Systemic Lupus Erythematosus 27835701 High-Throughput Sequencing Reveals Circulating miRNAs as Potential Biomarkers of Kidney Damage in Patients with Systemic Lupus Erythematosus. circulation_biomarker_diagnosis_ns hsa-mir-380 Systemic Lupus Erythematosus 27835701 High-Throughput Sequencing Reveals Circulating miRNAs as Potential Biomarkers of Kidney Damage in Patients with Systemic Lupus Erythematosus. circulation_biomarker_diagnosis_ns hsa-mir-556 Systemic Lupus Erythematosus 27835701 High-Throughput Sequencing Reveals Circulating miRNAs as Potential Biomarkers of Kidney Damage in Patients with Systemic Lupus Erythematosus. circulation_biomarker_diagnosis_ns hsa-mir-758 Systemic Lupus Erythematosus 27835701 High-Throughput Sequencing Reveals Circulating miRNAs as Potential Biomarkers of Kidney Damage in Patients with Systemic Lupus Erythematosus. circulation_biomarker_diagnosis_ns hsa-mir-106b Epilepsy 27840934 Identification of serum miRNAs differentially expressed in human epilepsy at seizure onset and post-seizure. circulation_biomarker_diagnosis_ns hsa-mir-15a Epilepsy 27840934 Identification of serum miRNAs differentially expressed in human epilepsy at seizure onset and post-seizure. circulation_biomarker_diagnosis_ns hsa-mir-30a Epilepsy 27840934 Identification of serum miRNAs differentially expressed in human epilepsy at seizure onset and post-seizure. circulation_biomarker_diagnosis_ns hsa-mir-378 Epilepsy 27840934 Identification of serum miRNAs differentially expressed in human epilepsy at seizure onset and post-seizure. circulation_biomarker_diagnosis_ns hsa-mir-16 Acute Cerebral Infarction 27846323 "Plasma MicroRNA-16 Is a Biomarker for Diagnosis, Stratification, and Prognosis of Hyperacute Cerebral Infarction." circulation_biomarker_diagnosis_ns hsa-mir-1266 Atrial Fibrillation 27855199 The Values of Coronary Circulating miRNAs in Patients with Atrial Fibrillation. circulation_biomarker_diagnosis_ns hsa-mir-3149 Atrial Fibrillation 27855199 The Values of Coronary Circulating miRNAs in Patients with Atrial Fibrillation. circulation_biomarker_diagnosis_ns hsa-mir-3171 Atrial Fibrillation 27855199 The Values of Coronary Circulating miRNAs in Patients with Atrial Fibrillation. circulation_biomarker_diagnosis_ns hsa-mir-4279 Atrial Fibrillation 27855199 The Values of Coronary Circulating miRNAs in Patients with Atrial Fibrillation. circulation_biomarker_diagnosis_ns hsa-mir-4666a Atrial Fibrillation 27855199 The Values of Coronary Circulating miRNAs in Patients with Atrial Fibrillation. circulation_biomarker_diagnosis_ns hsa-mir-892a Atrial Fibrillation 27855199 The Values of Coronary Circulating miRNAs in Patients with Atrial Fibrillation. circulation_biomarker_diagnosis_ns hsa-mir-222 Neoplasms [unspecific] 27859748 Use of Serum MicroRNAs as Biomarker for Hepatobiliary Diseases in Dogs. circulation_biomarker_diagnosis_ns hsa-mir-126 "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-146a "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-148 "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-150 "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-155 "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-21 "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-223 "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-24 "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-27a "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-28 "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-29b "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-30d "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-34a "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-93 "Diabetes Mellitus, Type 2" 27869909 Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-155 "Carcinoma, Colon" 27872469 Preoperative Serum MicroRNA-155 Expression Independently Predicts Postoperative Cognitive Dysfunction After Laparoscopic Surgery for Colon Cancer. circulation_biomarker_diagnosis_ns hsa-mir-34a "Carcinoma, Hepatocellular" 27893432 MicroRNA-34a expression levels in serum and intratumoral tissue can predict bone metastasis in patients with hepatocellular carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-126 Arteriosclerosis Obliterans 27900989 Negative Association of Circulating MicroRNA-126 with High-sensitive C-reactive Protein and Vascular Cell Adhesion Molecule-1 in Patients with Coronary Artery Disease Following Percutaneous Coronary Intervention. circulation_biomarker_diagnosis_ns hsa-mir-103 "Carcinoma, Gastric" 27909811 "Plasma microRNA-103, microRNA-107, and microRNA-194 levels are not biomarkers for human diffuse gastric cancer." circulation_biomarker_diagnosis_ns hsa-mir-107 "Carcinoma, Gastric" 27909811 "Plasma microRNA-103, microRNA-107, and microRNA-194 levels are not biomarkers for human diffuse gastric cancer." circulation_biomarker_diagnosis_ns hsa-mir-194 "Carcinoma, Gastric" 27909811 "Plasma microRNA-103, microRNA-107, and microRNA-194 levels are not biomarkers for human diffuse gastric cancer." circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Colon" 27910062 Plasma and saliva miR-21 expression in colorectal cancer patients. circulation_biomarker_diagnosis_ns hsa-mir-21 Osteosarcoma 27922432 miR-21 predicts poor prognosis in patients with osteosarcoma. circulation_biomarker_diagnosis_ns hsa-mir-133 Cardiomyopathy 27922664 Expression of Bcl-2 and microRNAs in cardiac tissues of patients with dilated cardiomyopathy. circulation_biomarker_diagnosis_ns hsa-mir-133a Cardiomyopathy 27922664 Expression of Bcl-2 and microRNAs in cardiac tissues of patients with dilated cardiomyopathy. circulation_biomarker_diagnosis_ns hsa-mir-133b Cardiomyopathy 27922664 Expression of Bcl-2 and microRNAs in cardiac tissues of patients with dilated cardiomyopathy. circulation_biomarker_diagnosis_ns hsa-mir-21 Cardiomyopathy 27922664 Expression of Bcl-2 and microRNAs in cardiac tissues of patients with dilated cardiomyopathy. circulation_biomarker_diagnosis_ns hsa-mir-29 Cardiomyopathy 27922664 Expression of Bcl-2 and microRNAs in cardiac tissues of patients with dilated cardiomyopathy. circulation_biomarker_diagnosis_ns hsa-mir-29a Cardiomyopathy 27922664 Expression of Bcl-2 and microRNAs in cardiac tissues of patients with dilated cardiomyopathy. circulation_biomarker_diagnosis_ns hsa-mir-29b Cardiomyopathy 27922664 Expression of Bcl-2 and microRNAs in cardiac tissues of patients with dilated cardiomyopathy. circulation_biomarker_diagnosis_ns hsa-mir-29c Cardiomyopathy 27922664 Expression of Bcl-2 and microRNAs in cardiac tissues of patients with dilated cardiomyopathy. circulation_biomarker_diagnosis_ns hsa-mir-126 Cardiovascular Diseases [unspecific] 27924211 Circulating miR-126 and miR-499 reflect progression of cardiovascular disease; correlations with uric acid and ejection fraction. circulation_biomarker_diagnosis_ns hsa-mir-122 "Fatty Liver, Non-Alcoholic" 27955628 Analysis of association between circulating miR-122 and histopathological features of nonalcoholic fatty liver disease in patients free of hepatocellular carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-34a "Fatty Liver, Non-Alcoholic" 27956809 Disease-specific miR-34a as diagnostic marker of non-alcoholic steatohepatitis in a Chinese population. circulation_biomarker_diagnosis_ns hsa-mir-21 Ischemia-Reperfusion Injury 27979484 MicroRNA-125b as a new potential biomarker on diagnosis of renal ischemia-reperfusion injury. circulation_biomarker_diagnosis_ns hsa-mir-199a Glioma 27981547 Circulating miR-199a-3p in plasma and its potential diagnostic and prognostic value in glioma. circulation_biomarker_diagnosis_ns hsa-mir-125 "Carcinoma, Gastric" 27986464 Circular RNA profile identifies circPVT1 as a proliferative factor and prognostic marker in gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-125b "Lymphoma, Burkitt" 27991481 "Circulating MicroRNA-21, MicroRNA-23a, and MicroRNA-125b as Biomarkers for Diagnosis and Prognosis of Burkitt Lymphoma in Children." circulation_biomarker_diagnosis_ns hsa-mir-21 "Lymphoma, Burkitt" 27991481 "Circulating MicroRNA-21, MicroRNA-23a, and MicroRNA-125b as Biomarkers for Diagnosis and Prognosis of Burkitt Lymphoma in Children." circulation_biomarker_diagnosis_ns hsa-mir-23a "Lymphoma, Burkitt" 27991481 "Circulating MicroRNA-21, MicroRNA-23a, and MicroRNA-125b as Biomarkers for Diagnosis and Prognosis of Burkitt Lymphoma in Children." circulation_biomarker_diagnosis_ns hsa-mir-29a Atherosclerosis 27997904 The Relationship of Plasma miR-29a and Oxidized Low Density Lipoprotein with Atherosclerosis. circulation_biomarker_diagnosis_ns hsa-mir-181a Acute Myocardial Infarction 27997916 Circulating miR-181a as a Potential Novel Biomarker for Diagnosis of Acute Myocardial Infarction. circulation_biomarker_diagnosis_ns hsa-mir-135a Colorectal Carcinoma 27998467 Expression and significance of serum microRNA-135a-5p level in colorectal cancer. circulation_biomarker_diagnosis_ns hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 28002496 "a combination of miRs 21, 205, 155 and possibly other miRs as serum biomarkers for early detection of NSCLC" circulation_biomarker_diagnosis_ns hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 28002496 "a combination of miRs 21, 205, 155 and possibly other miRs as serum biomarkers for early detection of NSCLC" circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 28002496 "a combination of miRs 21, 205, 155 and possibly other miRs as serum biomarkers for early detection of NSCLC" circulation_biomarker_diagnosis_ns hsa-mir-1246 "Carcinoma, Ovarian, Serous" 28017893 Circulating miRNA landscape identifies miR-1246 as promising diagnostic biomarker in high-grade serous ovarian carcinoma: A validation across two independent cohorts. circulation_biomarker_diagnosis_ns hsa-mir-375 "Squamous Cell Carcinoma, Oral" 28030794 Circulating miRNAs as biomarkers for oral squamous cell carcinoma recurrence in operated patients. circulation_biomarker_diagnosis_ns hsa-mir-10b "Carcinoma, Hepatocellular" 28049231 An Explorative Analysis for the Role of Serum miR-10b-3p Levels in Predicting Response to Sorafenib in Patients with Advanced Hepatocellular Carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-1 Lofgren Syndrome 28050119 The Serum Expression of Selected miRNAs in Pulmonary Sarcoidosis with/without L?fgren's Syndrome. circulation_biomarker_diagnosis_ns hsa-mir-146 Lofgren Syndrome 28050119 The Serum Expression of Selected miRNAs in Pulmonary Sarcoidosis with/without L?fgren's Syndrome. circulation_biomarker_diagnosis_ns hsa-mir-150 Lofgren Syndrome 28050119 The Serum Expression of Selected miRNAs in Pulmonary Sarcoidosis with/without L?fgren's Syndrome. circulation_biomarker_diagnosis_ns hsa-mir-16 Lofgren Syndrome 28050119 The Serum Expression of Selected miRNAs in Pulmonary Sarcoidosis with/without L?fgren's Syndrome. circulation_biomarker_diagnosis_ns hsa-mir-21 Lofgren Syndrome 28050119 The Serum Expression of Selected miRNAs in Pulmonary Sarcoidosis with/without L?fgren's Syndrome. circulation_biomarker_diagnosis_ns hsa-mir-212 Lofgren Syndrome 28050119 The Serum Expression of Selected miRNAs in Pulmonary Sarcoidosis with/without L?fgren's Syndrome. circulation_biomarker_diagnosis_ns hsa-mir-340 Lofgren Syndrome 28050119 The Serum Expression of Selected miRNAs in Pulmonary Sarcoidosis with/without L?fgren's Syndrome. circulation_biomarker_diagnosis_ns hsa-mir-425 Lofgren Syndrome 28050119 The Serum Expression of Selected miRNAs in Pulmonary Sarcoidosis with/without L?fgren's Syndrome. circulation_biomarker_diagnosis_ns hsa-mir-93 Lofgren Syndrome 28050119 The Serum Expression of Selected miRNAs in Pulmonary Sarcoidosis with/without L?fgren's Syndrome. circulation_biomarker_diagnosis_ns hsa-mir-145 Acute Myocardial Infarction 28051023 Circulating MicroRNA-145 is Associated with Acute Myocardial Infarction and Heart Failure. circulation_biomarker_diagnosis_ns hsa-mir-99a Acute Myocardial Infarction 28051249 The clinical value of circulating miR-99a in plasma of patients with acute myocardial infarction. circulation_biomarker_diagnosis_ns hsa-mir-378 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 28051256 Expression of serum microRNA-378 and its clinical significance in laryngeal squamous cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-1 Heart Failure 28052002 Circulating miR-1 as a potential biomarker of doxorubicin-induced cardiotoxicity in breast cancer patients. circulation_biomarker_diagnosis_ns hsa-mir-10b "Carcinoma, Lung, Non-Small-Cell" 28055956 Circulating exosomal microRNAs as prognostic biomarkers for non-small-cell lung cancer. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 28055956 Circulating exosomal microRNAs as prognostic biomarkers for non-small-cell lung cancer. circulation_biomarker_diagnosis_ns hsa-mir-23b "Carcinoma, Lung, Non-Small-Cell" 28055956 Circulating exosomal microRNAs as prognostic biomarkers for non-small-cell lung cancer. circulation_biomarker_diagnosis_ns hsa-mir-192 Kidney Injury 28056546 Urinary MicroRNA-30c-5p and MicroRNA-192-5p as potential biomarkers of ischemia-reperfusion-induced kidney injury. circulation_biomarker_diagnosis_ns hsa-mir-30c Kidney Injury 28056546 Urinary MicroRNA-30c-5p and MicroRNA-192-5p as potential biomarkers of ischemia-reperfusion-induced kidney injury. circulation_biomarker_diagnosis_ns hsa-mir-132 "Carcinoma, Breast" 28058628 A pilot study on plasma levels of micro-RNAs involved in angiogenesis and vascular maturation in patients with breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-221 "Carcinoma, Breast" 28058628 A pilot study on plasma levels of micro-RNAs involved in angiogenesis and vascular maturation in patients with breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-27b "Carcinoma, Breast" 28058628 A pilot study on plasma levels of micro-RNAs involved in angiogenesis and vascular maturation in patients with breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-221 "Carcinoma, Thyroid, Papillary" 28061868 "MiR-221, a potential prognostic biomarker for recurrence in papillary thyroid cancer." circulation_biomarker_diagnosis_ns hsa-mir-122 Liver Diseases [unspecific] 28070111 "circulating liver-specific miR-122 and miR-192 levels also increased 24 hr or later compared with ALT, suggesting that circulating miR-122 and miR-192 may serve as potential biomarkers to detect hepatotoxicity in cynomolgus monkeys" circulation_biomarker_diagnosis_ns hsa-mir-192 Liver Diseases [unspecific] 28070111 "circulating liver-specific miR-122 and miR-192 levels also increased 24 hr or later compared with ALT, suggesting that circulating miR-122 and miR-192 may serve as potential biomarkers to detect hepatotoxicity in cynomolgus monkeys" circulation_biomarker_diagnosis_ns hsa-let-7a Chronic Kidney Disease 28077372 "miRNA are associated with kidney fibrosis, and specific urinary and plasma miRNA profile may have diagnostic and prognostic utility in CKD" circulation_biomarker_diagnosis_ns hsa-mir-1281 Chronic Kidney Disease 28077372 "miRNA are associated with kidney fibrosis, and specific urinary and plasma miRNA profile may have diagnostic and prognostic utility in CKD" circulation_biomarker_diagnosis_ns hsa-mir-130a Chronic Kidney Disease 28077372 "miRNA are associated with kidney fibrosis, and specific urinary and plasma miRNA profile may have diagnostic and prognostic utility in CKD" circulation_biomarker_diagnosis_ns hsa-mir-1825 Chronic Kidney Disease 28077372 "miRNA are associated with kidney fibrosis, and specific urinary and plasma miRNA profile may have diagnostic and prognostic utility in CKD" circulation_biomarker_diagnosis_ns hsa-mir-423 Chronic Kidney Disease 28077372 "miRNA are associated with kidney fibrosis, and specific urinary and plasma miRNA profile may have diagnostic and prognostic utility in CKD" circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Breast, Triple Negative" 28078851 Mechanism of serum miR-21 in the pathogenesis of familial and triple negative breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-107 "Carcinoma, Hepatocellular" 28079796 Serum microRNA panel for early diagnosis of the onset of hepatocellular carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-16 "Carcinoma, Hepatocellular" 28079796 Serum microRNA panel for early diagnosis of the onset of hepatocellular carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-3126 "Carcinoma, Hepatocellular" 28079796 Serum microRNA panel for early diagnosis of the onset of hepatocellular carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-92 "Carcinoma, Hepatocellular" 28079796 Serum microRNA panel for early diagnosis of the onset of hepatocellular carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-19b "Carcinoma, Prostate" 28091918 Changes in the Level of Circulating hsa-miR-297 and hsa-miR-19b-3p miRNA Are Associated with Generalization of Prostate Cancer. circulation_biomarker_diagnosis_ns hsa-mir-297 "Carcinoma, Prostate" 28091918 Changes in the Level of Circulating hsa-miR-297 and hsa-miR-19b-3p miRNA Are Associated with Generalization of Prostate Cancer. circulation_biomarker_diagnosis_ns hsa-mir-196a "Squamous Cell Carcinoma, Esophageal" 28095062 MicroRNA-196a as a Potential Diagnostic Biomarker for Esophageal Squamous Cell Carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-92a "Carcinoma, Lung, Small-Cell" 28106539 Plasma miR-92a-2 as a biomarker for small cell lung cancer. circulation_biomarker_diagnosis_ns hsa-mir-142 Traumatic Brain Injury 28117263 Plasma micro-RNA biomarkers for diagnosis and prognosis after traumatic brain injury: A pilot study. circulation_biomarker_diagnosis_ns hsa-mir-423 Traumatic Brain Injury 28117263 Plasma micro-RNA biomarkers for diagnosis and prognosis after traumatic brain injury: A pilot study. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Gastric" 28121346 miR-21 can be used for the diagnosis of gastric cancer and prognosis of lymph node metastasis in gastric cancer circulation_biomarker_diagnosis_ns hsa-mir-222 "Adenocarcinoma, Lung" 28123597 Identification of A Panel of Serum microRNAs as Biomarkers for Early Detection of Lung Adenocarcinoma. circulation_biomarker_diagnosis_ns hsa-mir-223 "Adenocarcinoma, Lung" 28123597 Identification of A Panel of Serum microRNAs as Biomarkers for Early Detection of Lung Adenocarcinoma. circulation_biomarker_diagnosis_ns hsa-mir-208b Myocardial Infarction 28164501 Circulating miR-208b: A Potentially Sensitive and Reliable Biomarker for the Diagnosis and Prognosis of Acute Myocardial Infarction. circulation_biomarker_diagnosis_ns hsa-mir-146a Sepsis 28164567 The Prognostic Value of Plasma MicroRNA-155 and MicroRNA-146a Level in Severe Sepsis and Sepsis-Induced Acute Lung Injury Patients. circulation_biomarker_diagnosis_ns hsa-mir-155 Sepsis 28164567 The Prognostic Value of Plasma MicroRNA-155 and MicroRNA-146a Level in Severe Sepsis and Sepsis-Induced Acute Lung Injury Patients. circulation_biomarker_diagnosis_ns hsa-mir-19a Colorectal Carcinoma 28177881 A panel of microRNA signature in serum for colorectal cancer diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-21 Colorectal Carcinoma 28177881 A panel of microRNA signature in serum for colorectal cancer diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-425 Colorectal Carcinoma 28177881 A panel of microRNA signature in serum for colorectal cancer diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-23a Polycystic Ovarian Syndrome 28193283 Circulatory microRNA 23a and microRNA 23b and polycystic ovary syndrome (PCOS): the effects of body mass index and sex hormones in an Eastern Han Chinese population. circulation_biomarker_diagnosis_ns hsa-mir-23b Polycystic Ovarian Syndrome 28193283 Circulatory microRNA 23a and microRNA 23b and polycystic ovary syndrome (PCOS): the effects of body mass index and sex hormones in an Eastern Han Chinese population. circulation_biomarker_diagnosis_ns hsa-mir-145 Coronary Artery Disease 28205634 "Circulating miR-155, miR-145 and let-7c as diagnostic biomarkers of the coronary artery disease." circulation_biomarker_diagnosis_ns hsa-mir-122 Chronic Hepatitis C 28211229 Serum microRNAs as predictors for liver fibrosis staging in hepatitis C virus-associated chronic liver disease patients. circulation_biomarker_diagnosis_ns hsa-mir-107 "Neuralgia, Postherpetic" 28225487 Comparing serum microRNA levels of acute herpes zoster patients with those of postherpetic neuralgia patients. circulation_biomarker_diagnosis_ns hsa-mir-127 "Neuralgia, Postherpetic" 28225487 Comparing serum microRNA levels of acute herpes zoster patients with those of postherpetic neuralgia patients. circulation_biomarker_diagnosis_ns hsa-mir-34c "Neuralgia, Postherpetic" 28225487 Comparing serum microRNA levels of acute herpes zoster patients with those of postherpetic neuralgia patients. circulation_biomarker_diagnosis_ns hsa-mir-486 "Neuralgia, Postherpetic" 28225487 Comparing serum microRNA levels of acute herpes zoster patients with those of postherpetic neuralgia patients. circulation_biomarker_diagnosis_ns hsa-mir-892b "Neuralgia, Postherpetic" 28225487 Comparing serum microRNA levels of acute herpes zoster patients with those of postherpetic neuralgia patients. circulation_biomarker_diagnosis_ns hsa-let-7a "Carcinoma, Pancreatic" 28232049 A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-10b "Carcinoma, Pancreatic" 28232049 A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-181a "Carcinoma, Pancreatic" 28232049 A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Pancreatic" 28232049 A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-30c "Carcinoma, Pancreatic" 28232049 A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-122 Hepatitis C Virus Infection 28232800 Circulating ECV-Associated miRNAs as Potential Clinical Biomarkers in Early Stage HBV and HCV Induced Liver Fibrosis. circulation_biomarker_diagnosis_ns hsa-mir-200b Hepatitis C Virus Infection 28232800 Circulating ECV-Associated miRNAs as Potential Clinical Biomarkers in Early Stage HBV and HCV Induced Liver Fibrosis. circulation_biomarker_diagnosis_ns hsa-mir-146b "Carcinoma, Bladder" 28239818 Identification of miR-146b-5p in tissues as a novel biomarker for prognosis of gallbladder carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-383 "Carcinoma, Gastric" 28243881 "The Value of MiR-383, an Intronic MiRNA, as a Diagnostic and Prognostic Biomarker in Intestinal-Type Gastric Cancer." circulation_biomarker_diagnosis_ns hsa-mir-193a Focal Segmental Glomerulosclerosis 28246603 Urinary Exosomal miR-193a Can Be a Potential Biomarker for the Diagnosis of Primary Focal Segmental Glomerulosclerosis in Children. circulation_biomarker_diagnosis_ns hsa-mir-126 "Carcinoma, Lung, Non-Small-Cell" 28253725 Predicative values of serum microRNA-22 and microRNA-126 levels for non-small cell lung cancer development and metastasis: a case-control study. circulation_biomarker_diagnosis_ns hsa-mir-22 "Carcinoma, Lung, Non-Small-Cell" 28253725 Predicative values of serum microRNA-22 and microRNA-126 levels for non-small cell lung cancer development and metastasis: a case-control study. circulation_biomarker_diagnosis_ns hsa-mir-144 "Diabetes Mellitus, Type 2" 28260062 Serum microRNA profiling and bioinformatics analysis of patients with type 2 diabetes mellitus in a Chinese population. circulation_biomarker_diagnosis_ns hsa-mir-409 "Diabetes Mellitus, Type 2" 28260062 Serum microRNA profiling and bioinformatics analysis of patients with type 2 diabetes mellitus in a Chinese population. circulation_biomarker_diagnosis_ns hsa-mir-454 "Diabetes Mellitus, Type 2" 28260062 Serum microRNA profiling and bioinformatics analysis of patients with type 2 diabetes mellitus in a Chinese population. circulation_biomarker_diagnosis_ns hsa-mir-455 "Diabetes Mellitus, Type 2" 28260062 Serum microRNA profiling and bioinformatics analysis of patients with type 2 diabetes mellitus in a Chinese population. circulation_biomarker_diagnosis_ns hsa-mir-665 "Diabetes Mellitus, Type 2" 28260062 Serum microRNA profiling and bioinformatics analysis of patients with type 2 diabetes mellitus in a Chinese population. circulation_biomarker_diagnosis_ns hsa-mir-766 "Diabetes Mellitus, Type 2" 28260062 Serum microRNA profiling and bioinformatics analysis of patients with type 2 diabetes mellitus in a Chinese population. circulation_biomarker_diagnosis_ns hsa-mir-96 "Diabetes Mellitus, Type 2" 28260062 Serum microRNA profiling and bioinformatics analysis of patients with type 2 diabetes mellitus in a Chinese population. circulation_biomarker_diagnosis_ns hsa-mir-208b Acute Myocardial Infarction 28272696 A meta-analysis of the relations between blood microRNA-208b detection and acute myocardial infarction. circulation_biomarker_diagnosis_ns hsa-mir-141 "Carcinoma, Thyroid, Papillary" 28288173 Microarray profiling of circular RNAs in human papillary thyroid carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-200a "Carcinoma, Thyroid, Papillary" 28288173 Microarray profiling of circular RNAs in human papillary thyroid carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-132 Mesothelioma 28321148 Circulating miR-132-3p as a Candidate Diagnostic Biomarker for Malignant Mesothelioma. circulation_biomarker_diagnosis_ns hsa-mir-124 Acute Myocardial Infarction 28338188 Implication of peripheral blood miRNA-124 in predicting acute myocardial infarction. circulation_biomarker_diagnosis_ns hsa-mir-182 "Carcinoma, Breast" 28359916 Identification of microRNA biomarkers in the blood of breast cancer patients based on microRNA profiling. circulation_biomarker_diagnosis_ns hsa-mir-30b "Carcinoma, Breast" 28359916 Identification of microRNA biomarkers in the blood of breast cancer patients based on microRNA profiling. circulation_biomarker_diagnosis_ns hsa-mir-374b "Carcinoma, Breast" 28359916 Identification of microRNA biomarkers in the blood of breast cancer patients based on microRNA profiling. circulation_biomarker_diagnosis_ns hsa-mir-942 "Carcinoma, Breast" 28359916 Identification of microRNA biomarkers in the blood of breast cancer patients based on microRNA profiling. circulation_biomarker_diagnosis_ns hsa-mir-96 "Carcinoma, Breast" 28359916 Identification of microRNA biomarkers in the blood of breast cancer patients based on microRNA profiling. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Colon" 28376502 Circulating Exosomal MicroRNA-21 as a Biomarker in Each Tumor Stage of Colorectal Cancer. circulation_biomarker_diagnosis_ns hsa-mir-126 Cardiovascular Diseases [unspecific] 28379027 Regulatory RNAs and cardiovascular disease - with a special focus on circulating microRNAs. circulation_biomarker_diagnosis_ns hsa-mir-143 Cardiovascular Diseases [unspecific] 28379027 Regulatory RNAs and cardiovascular disease - with a special focus on circulating microRNAs. circulation_biomarker_diagnosis_ns hsa-mir-145 Cardiovascular Diseases [unspecific] 28379027 Regulatory RNAs and cardiovascular disease - with a special focus on circulating microRNAs. circulation_biomarker_diagnosis_ns hsa-mir-221 Cardiovascular Diseases [unspecific] 28379027 Regulatory RNAs and cardiovascular disease - with a special focus on circulating microRNAs. circulation_biomarker_diagnosis_ns hsa-mir-222 Cardiovascular Diseases [unspecific] 28379027 Regulatory RNAs and cardiovascular disease - with a special focus on circulating microRNAs. circulation_biomarker_diagnosis_ns hsa-mir-26 Cardiovascular Diseases [unspecific] 28379027 Regulatory RNAs and cardiovascular disease - with a special focus on circulating microRNAs. circulation_biomarker_diagnosis_ns hsa-mir-33 Cardiovascular Diseases [unspecific] 28379027 Regulatory RNAs and cardiovascular disease - with a special focus on circulating microRNAs. circulation_biomarker_diagnosis_ns hsa-mir-758 Cardiovascular Diseases [unspecific] 28379027 Regulatory RNAs and cardiovascular disease - with a special focus on circulating microRNAs. circulation_biomarker_diagnosis_ns hsa-mir-221 Glioblastoma 28381184 "microRNA expression levels was built, which has the potential to be used in clinics and thus to improve the survival status of glioblastoma multiforme patients" circulation_biomarker_diagnosis_ns hsa-mir-222 Glioblastoma 28381184 "microRNA expression levels was built, which has the potential to be used in clinics and thus to improve the survival status of glioblastoma multiforme patients" circulation_biomarker_diagnosis_ns hsa-mir-134 Mesial Temporal Lobe Epilepsy 28384161 MicroRNA hsa-miR-134 is a circulating biomarker for mesial temporal lobe epilepsy. circulation_biomarker_diagnosis_ns hsa-mir-31 Foot-and-Mouth Disease 28388926 Proof-of-concept study: profile of circulating microRNAs in Bovine serum harvested during acute and persistent FMDV infection. circulation_biomarker_diagnosis_ns hsa-mir-20a Gastric Neoplasms 28413641 Serum miR-20a is a promising biomarker for gastric cancer. circulation_biomarker_diagnosis_ns hsa-let-7g Colon Neoplasms 28415718 Exosomal microRNAs isolated from plasma of mesenteric veins linked to liver metastases in resected patients with colon cancer. circulation_biomarker_diagnosis_ns hsa-mir-155 Colon Neoplasms 28415718 Exosomal microRNAs isolated from plasma of mesenteric veins linked to liver metastases in resected patients with colon cancer. circulation_biomarker_diagnosis_ns hsa-mir-126 "Aortic Aneurysm, Abdominal" 28425970 Aneurysm-Specific miR-221 and miR-146a Participates in Human Thoracic and Abdominal Aortic Aneurysms. circulation_biomarker_diagnosis_ns hsa-mir-145 "Aortic Aneurysm, Abdominal" 28425970 Aneurysm-Specific miR-221 and miR-146a Participates in Human Thoracic and Abdominal Aortic Aneurysms. circulation_biomarker_diagnosis_ns hsa-mir-361 Essential Hypertension 28445253 micro-RNA screening and prediction model construction for diagnosis of salt-sensitive essential hypertension. circulation_biomarker_diagnosis_ns hsa-mir-362 Essential Hypertension 28445253 micro-RNA screening and prediction model construction for diagnosis of salt-sensitive essential hypertension. circulation_biomarker_diagnosis_ns hsa-mir-16 Multiple Myeloma 28446295 Circulating Serum MicroRNA as Diagnostic Biomarkers for Multiple Myeloma. circulation_biomarker_diagnosis_ns hsa-mir-375 "Adenocarcinoma, Lung" 28449331 miR-130A as a diagnostic marker to differentiate malignant mesothelioma from lung adenocarcinoma in pleural effusion cytology. circulation_biomarker_diagnosis_ns hsa-mir-196a Pancreatic Adenocarcinoma 28466015 "Evaluation of Plasma MicroRNAs as Diagnostic and Prognostic Biomarkers in Pancreatic Adenocarcinoma: miR-196a and miR-210 Could Be Negative and Positive Prognostic Markers, Respectively." circulation_biomarker_diagnosis_ns hsa-mir-210 Pancreatic Adenocarcinoma 28466015 "Evaluation of Plasma MicroRNAs as Diagnostic and Prognostic Biomarkers in Pancreatic Adenocarcinoma: miR-196a and miR-210 Could Be Negative and Positive Prognostic Markers, Respectively." circulation_biomarker_diagnosis_ns hsa-mir-149 Cutaneous Melanoma 28466785 Identification of plasma microRNAs as new potential biomarkers with high diagnostic power in human cutaneous melanoma. circulation_biomarker_diagnosis_ns hsa-mir-150 Cutaneous Melanoma 28466785 Identification of plasma microRNAs as new potential biomarkers with high diagnostic power in human cutaneous melanoma. circulation_biomarker_diagnosis_ns hsa-mir-15b Cutaneous Melanoma 28466785 Identification of plasma microRNAs as new potential biomarkers with high diagnostic power in human cutaneous melanoma. circulation_biomarker_diagnosis_ns hsa-mir-193a Cutaneous Melanoma 28466785 Identification of plasma microRNAs as new potential biomarkers with high diagnostic power in human cutaneous melanoma. circulation_biomarker_diagnosis_ns hsa-mir-524 Cutaneous Melanoma 28466785 Identification of plasma microRNAs as new potential biomarkers with high diagnostic power in human cutaneous melanoma. circulation_biomarker_diagnosis_ns hsa-mir-873 Ectopic Pregnancy 28472791 MicroRNA-873 is a Potential Serum Biomarker for the Detection of Ectopic Pregnancy. circulation_biomarker_diagnosis_ns hsa-mir-1825 Glioma 28475008 A novel serum microRNA-based identification and classification biomarker of human glioma. circulation_biomarker_diagnosis_ns hsa-mir-27a Heart Failure 28475616 Rodent heart failure models do not reflect the human circulating microRNA signature in heart failure. circulation_biomarker_diagnosis_ns hsa-mir-125b Kidney Diseases [unspecific] 28522697 Circulating MicroRNA-125b Predicts the Presence and Progression of Uremic Vascular Calcification. circulation_biomarker_diagnosis_ns hsa-mir-146a Sepsis 28552958 Characterization of basal and lipopolysaccharide-induced microRNA expression in equine peripheral blood mononuclear cells using Next-Generation Sequencing. circulation_biomarker_diagnosis_ns hsa-mir-155 Sepsis 28552958 Characterization of basal and lipopolysaccharide-induced microRNA expression in equine peripheral blood mononuclear cells using Next-Generation Sequencing. circulation_biomarker_diagnosis_ns hsa-mir-206 Pulmonary Hypertension 28554172 The Circulating MicroRNA-206 Level Predicts the Severity of Pulmonary Hypertension in Patients with Left Heart Diseases. circulation_biomarker_diagnosis_ns hsa-mir-210 Rheumatoid Arthritis 28560518 miR-210 expression in PBMCs from patients with systemic lupus erythematosus and rheumatoid arthritis. circulation_biomarker_diagnosis_ns hsa-mir-210 Systemic Lupus Erythematosus 28560518 miR-210 expression in PBMCs from patients with systemic lupus erythematosus and rheumatoid arthritis. circulation_biomarker_diagnosis_ns hsa-mir-182 Chronic Hepatitis B 28562750 Circulating microRNA as a marker for predicting liver disease progression in patients with chronic hepatitis B. circulation_biomarker_diagnosis_ns hsa-mir-125a Kideny Transplant Rejection 28577875 "Circulating miR-150, miR-192, miR-200b, and miR-423-3p as Non-invasive Biomarkers of Chronic Allograft Dysfunction." circulation_biomarker_diagnosis_ns hsa-mir-150 Kideny Transplant Rejection 28577875 "Circulating miR-150, miR-192, miR-200b, and miR-423-3p as Non-invasive Biomarkers of Chronic Allograft Dysfunction." circulation_biomarker_diagnosis_ns hsa-mir-192 Kideny Transplant Rejection 28577875 "Circulating miR-150, miR-192, miR-200b, and miR-423-3p as Non-invasive Biomarkers of Chronic Allograft Dysfunction." circulation_biomarker_diagnosis_ns hsa-mir-200b Kideny Transplant Rejection 28577875 "Circulating miR-150, miR-192, miR-200b, and miR-423-3p as Non-invasive Biomarkers of Chronic Allograft Dysfunction." circulation_biomarker_diagnosis_ns hsa-mir-423 Kideny Transplant Rejection 28577875 "Circulating miR-150, miR-192, miR-200b, and miR-423-3p as Non-invasive Biomarkers of Chronic Allograft Dysfunction." circulation_biomarker_diagnosis_ns hsa-mir-499 Myocardial Infarction 28614255 miRNA-499 had better diagnostic accuracy over other miRNAs circulation_biomarker_diagnosis_ns hsa-mir-130a Coronary Artery Disease 28628920 "Predictive Effects of Circulating miR-221, miR-130a and miR-155 for Coronary Heart Disease: A Multi-Ethnic Study in China." circulation_biomarker_diagnosis_ns hsa-mir-155 Coronary Artery Disease 28628920 "Predictive Effects of Circulating miR-221, miR-130a and miR-155 for Coronary Heart Disease: A Multi-Ethnic Study in China." circulation_biomarker_diagnosis_ns hsa-mir-221 Coronary Artery Disease 28628920 "Predictive Effects of Circulating miR-221, miR-130a and miR-155 for Coronary Heart Disease: A Multi-Ethnic Study in China." circulation_biomarker_diagnosis_ns hsa-mir-143 Hyperhomocysteinemia 28633641 Expression levels of atherosclerosis-associated miR-143 and miR-145 in the plasma of patients with hyperhomocysteinaemia. circulation_biomarker_diagnosis_ns hsa-mir-145 Hyperhomocysteinemia 28633641 Expression levels of atherosclerosis-associated miR-143 and miR-145 in the plasma of patients with hyperhomocysteinaemia. circulation_biomarker_diagnosis_ns hsa-mir-16 "Carcinoma, Lung, Non-Small-Cell" 28634901 "Changes in plasma miR-9, miR-16, miR-205 and miR-486 levels after non-small cell lung cancer resection." circulation_biomarker_diagnosis_ns hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 28634901 "Changes in plasma miR-9, miR-16, miR-205 and miR-486 levels after non-small cell lung cancer resection." circulation_biomarker_diagnosis_ns hsa-mir-375 Neoplasms [unspecific] 28638226 Validation of a serum microRNA panel as biomarkers for early diagnosis of hepatocellular carcinoma post-hepatitis C infection in Egyptian patients. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Gastric" 28641313 Evaluation of serum microRNA biomarkers for gastric cancer based on blood and tissue pools profiling: the importance of miR-21 and miR-331. circulation_biomarker_diagnosis_ns hsa-mir-331 "Carcinoma, Gastric" 28641313 Evaluation of serum microRNA biomarkers for gastric cancer based on blood and tissue pools profiling: the importance of miR-21 and miR-331. circulation_biomarker_diagnosis_ns hsa-mir-146a Osteoarthritis 28647559 "miRNA-146a, miRNA-155 and JNK expression levels in peripheral blood mononuclear cells according to grade of knee osteoarthritis." circulation_biomarker_diagnosis_ns hsa-mir-155 Osteoarthritis 28647559 "miRNA-146a, miRNA-155 and JNK expression levels in peripheral blood mononuclear cells according to grade of knee osteoarthritis." circulation_biomarker_diagnosis_ns hsa-mir-1 Myocardial Infarction 28663047 Diagnostic and prognostic value of miR-1 and miR-29b on adverse ventricular remodeling after acute myocardial infarction circulation_biomarker_diagnosis_ns hsa-mir-29b Myocardial Infarction 28663047 Diagnostic and prognostic value of miR-1 and miR-29b on adverse ventricular remodeling after acute myocardial infarction circulation_biomarker_diagnosis_ns hsa-mir-133a Heart Failure 28666417 Identifying differential miR and gene consensus patterns in peripheral blood of patients with cardiovascular diseases from literature data. circulation_biomarker_diagnosis_ns hsa-mir-155 Preeclampsia 28700503 MiR-210 and miR-155 as potential diagnostic markers for pre-eclampsia pregnancies. circulation_biomarker_diagnosis_ns hsa-mir-210 Preeclampsia 28700503 MiR-210 and miR-155 as potential diagnostic markers for pre-eclampsia pregnancies. circulation_biomarker_diagnosis_ns hsa-mir-21 Osteosarcoma 28742209 The expression significance of serum MiR-21 in patients with osteosarcoma and its relationship with chemosensitivity. circulation_biomarker_diagnosis_ns hsa-mir-122 "Carcinoma, Hepatocellular" 28750770 Circulating microRNAs panel as a diagnostic tool for discrimination of HCV-associated hepatocellular carcinoma circulation_biomarker_diagnosis_ns hsa-mir-122 Ischemic Heart Disease 28768728 "six miRNA mimics (miR-34a, -122, -133a, -142, -146a, and -208a) induced cytokine production in a dose-dependent manner" circulation_biomarker_diagnosis_ns hsa-mir-133a Ischemic Heart Disease 28768728 "six miRNA mimics (miR-34a, -122, -133a, -142, -146a, and -208a) induced cytokine production in a dose-dependent manner" circulation_biomarker_diagnosis_ns hsa-mir-142 Ischemic Heart Disease 28768728 "six miRNA mimics (miR-34a, -122, -133a, -142, -146a, and -208a) induced cytokine production in a dose-dependent manner" circulation_biomarker_diagnosis_ns hsa-mir-146a Ischemic Heart Disease 28768728 "six miRNA mimics (miR-34a, -122, -133a, -142, -146a, and -208a) induced cytokine production in a dose-dependent manner" circulation_biomarker_diagnosis_ns hsa-mir-208a Ischemic Heart Disease 28768728 "six miRNA mimics (miR-34a, -122, -133a, -142, -146a, and -208a) induced cytokine production in a dose-dependent manner" circulation_biomarker_diagnosis_ns hsa-mir-34a Ischemic Heart Disease 28768728 "six miRNA mimics (miR-34a, -122, -133a, -142, -146a, and -208a) induced cytokine production in a dose-dependent manner" circulation_biomarker_diagnosis_ns hsa-mir-155 Rheumatoid Arthritis 28782994 Serum miR-210 and miR-155 expression levels as novel biomarkers for rheumatoid arthritis diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-210 Rheumatoid Arthritis 28782994 Serum miR-210 and miR-155 expression levels as novel biomarkers for rheumatoid arthritis diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-33a Hyperlipoproteinemia Type III 28811385 Circulating miR-200c is up-regulated in paediatric patients with familial hypercholesterolaemia and correlates with miR-33a/b levels: implication of a ZEB1-dependent mechanism. circulation_biomarker_diagnosis_ns hsa-mir-33b Hyperlipoproteinemia Type III 28811385 Circulating miR-200c is up-regulated in paediatric patients with familial hypercholesterolaemia and correlates with miR-33a/b levels: implication of a ZEB1-dependent mechanism. circulation_biomarker_diagnosis_ns hsa-mir-454 Glioma 28815332 "A signature composed of miR-93, miR-590-3p, and miR-454 enabled to nearly perfectly separate patients from controls" circulation_biomarker_diagnosis_ns hsa-mir-590 Glioma 28815332 "A signature composed of miR-93, miR-590-3p, and miR-454 enabled to nearly perfectly separate patients from controls" circulation_biomarker_diagnosis_ns hsa-mir-93 Glioma 28815332 "A signature composed of miR-93, miR-590-3p, and miR-454 enabled to nearly perfectly separate patients from controls" circulation_biomarker_diagnosis_ns hsa-mir-181a "Leukemia, Lymphocytic, Chronic, B-Cell" 28830603 Comparison of microRNA expression in high-count monoclonal B-cell lymphocytosis and Binet A chronic lymphocytic leukemia circulation_biomarker_diagnosis_ns hsa-mir-181a Acute Respiratory Distress Syndrome 28856588 "miR-181a and miR-92a are risk biomarkers for ARDS, whereas miR-424 is a protective biomarker" circulation_biomarker_diagnosis_ns hsa-mir-424 Acute Respiratory Distress Syndrome 28856588 "miR-181a and miR-92a are risk biomarkers for ARDS, whereas miR-424 is a protective biomarker" circulation_biomarker_diagnosis_ns hsa-mir-92a Acute Respiratory Distress Syndrome 28856588 "miR-181a and miR-92a are risk biomarkers for ARDS, whereas miR-424 is a protective biomarker" circulation_biomarker_diagnosis_ns hsa-mir-146a Peripheral Nervous System Diseases 28870579 Aberrant microRNA expression in patients with painful peripheral neuropathies. circulation_biomarker_diagnosis_ns hsa-mir-155 Peripheral Nervous System Diseases 28870579 Aberrant microRNA expression in patients with painful peripheral neuropathies. circulation_biomarker_diagnosis_ns hsa-mir-21 Peripheral Nervous System Diseases 28870579 Aberrant microRNA expression in patients with painful peripheral neuropathies. circulation_biomarker_diagnosis_ns hsa-mir-9 Schizophrenia 28877483 Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells. circulation_biomarker_diagnosis_ns hsa-mir-449a Celiac Disease 28878141 Intestinal and Circulating MicroRNAs in Coeliac Disease. circulation_biomarker_diagnosis_ns hsa-mir-23a "Carcinoma, Hepatocellular" 28878865 MicroRNA 23a can be used as a screening test for early detection of HCC circulation_biomarker_diagnosis_ns hsa-mir-143 "Leukemia, Myeloid, Acute" 28890884 "Circulating miR-92a, miR-143 and miR-342 in Plasma are Novel Potential Biomarkers for Acute Myeloid Leukemia" circulation_biomarker_diagnosis_ns hsa-mir-342 "Leukemia, Myeloid, Acute" 28890884 "Circulating miR-92a, miR-143 and miR-342 in Plasma are Novel Potential Biomarkers for Acute Myeloid Leukemia" circulation_biomarker_diagnosis_ns hsa-mir-92a "Leukemia, Myeloid, Acute" 28890884 "Circulating miR-92a, miR-143 and miR-342 in Plasma are Novel Potential Biomarkers for Acute Myeloid Leukemia" circulation_biomarker_diagnosis_ns hsa-mir-155 Cervical Neoplasms 28934937 "MiR-9, miR-21, and miR-155 as potential biomarkers for HPV positive and negative cervical cancer" circulation_biomarker_diagnosis_ns hsa-mir-21 Cervical Neoplasms 28934937 "MiR-9, miR-21, and miR-155 as potential biomarkers for HPV positive and negative cervical cancer" circulation_biomarker_diagnosis_ns hsa-mir-9 Cervical Neoplasms 28934937 "MiR-9, miR-21, and miR-155 as potential biomarkers for HPV positive and negative cervical cancer" circulation_biomarker_diagnosis_ns hsa-mir-21 Human Immunodeficiency Virus Infection 28955339 Deregulated MicroRNA-21 Expression in Monocytes from HIV-Infected Patients Contributes to Elevated IP-10 Secretion in HIV Infection. circulation_biomarker_diagnosis_ns hsa-mir-100 "Diabetes Mellitus, Type 1" 28986402 "Regarding circulating miRNAs, 11 were consistently dysregulated in T1DM patients compared to controls: miR-21-5p, miR-24-3p, miR-100-5p, miR-146a-5p, miR-148a-3p, miR-150-5p, miR-181a-5p, miR-210-5p, miR-342-3p, miR-375 and miR-1275" circulation_biomarker_diagnosis_ns hsa-mir-1275 "Diabetes Mellitus, Type 1" 28986402 "Regarding circulating miRNAs, 11 were consistently dysregulated in T1DM patients compared to controls: miR-21-5p, miR-24-3p, miR-100-5p, miR-146a-5p, miR-148a-3p, miR-150-5p, miR-181a-5p, miR-210-5p, miR-342-3p, miR-375 and miR-1275" circulation_biomarker_diagnosis_ns hsa-mir-146a "Diabetes Mellitus, Type 1" 28986402 "Regarding circulating miRNAs, 11 were consistently dysregulated in T1DM patients compared to controls: miR-21-5p, miR-24-3p, miR-100-5p, miR-146a-5p, miR-148a-3p, miR-150-5p, miR-181a-5p, miR-210-5p, miR-342-3p, miR-375 and miR-1275" circulation_biomarker_diagnosis_ns hsa-mir-148a "Diabetes Mellitus, Type 1" 28986402 "Regarding circulating miRNAs, 11 were consistently dysregulated in T1DM patients compared to controls: miR-21-5p, miR-24-3p, miR-100-5p, miR-146a-5p, miR-148a-3p, miR-150-5p, miR-181a-5p, miR-210-5p, miR-342-3p, miR-375 and miR-1275" circulation_biomarker_diagnosis_ns hsa-mir-150 "Diabetes Mellitus, Type 1" 28986402 "Regarding circulating miRNAs, 11 were consistently dysregulated in T1DM patients compared to controls: miR-21-5p, miR-24-3p, miR-100-5p, miR-146a-5p, miR-148a-3p, miR-150-5p, miR-181a-5p, miR-210-5p, miR-342-3p, miR-375 and miR-1275" circulation_biomarker_diagnosis_ns hsa-mir-181a "Diabetes Mellitus, Type 1" 28986402 "Regarding circulating miRNAs, 11 were consistently dysregulated in T1DM patients compared to controls: miR-21-5p, miR-24-3p, miR-100-5p, miR-146a-5p, miR-148a-3p, miR-150-5p, miR-181a-5p, miR-210-5p, miR-342-3p, miR-375 and miR-1275" circulation_biomarker_diagnosis_ns hsa-mir-21 "Diabetes Mellitus, Type 1" 28986402 "Regarding circulating miRNAs, 11 were consistently dysregulated in T1DM patients compared to controls: miR-21-5p, miR-24-3p, miR-100-5p, miR-146a-5p, miR-148a-3p, miR-150-5p, miR-181a-5p, miR-210-5p, miR-342-3p, miR-375 and miR-1275" circulation_biomarker_diagnosis_ns hsa-mir-210 "Diabetes Mellitus, Type 1" 28986402 "Regarding circulating miRNAs, 11 were consistently dysregulated in T1DM patients compared to controls: miR-21-5p, miR-24-3p, miR-100-5p, miR-146a-5p, miR-148a-3p, miR-150-5p, miR-181a-5p, miR-210-5p, miR-342-3p, miR-375 and miR-1275" circulation_biomarker_diagnosis_ns hsa-mir-24 "Diabetes Mellitus, Type 1" 28986402 "Regarding circulating miRNAs, 11 were consistently dysregulated in T1DM patients compared to controls: miR-21-5p, miR-24-3p, miR-100-5p, miR-146a-5p, miR-148a-3p, miR-150-5p, miR-181a-5p, miR-210-5p, miR-342-3p, miR-375 and miR-1275" circulation_biomarker_diagnosis_ns hsa-mir-342 "Diabetes Mellitus, Type 1" 28986402 "Regarding circulating miRNAs, 11 were consistently dysregulated in T1DM patients compared to controls: miR-21-5p, miR-24-3p, miR-100-5p, miR-146a-5p, miR-148a-3p, miR-150-5p, miR-181a-5p, miR-210-5p, miR-342-3p, miR-375 and miR-1275" circulation_biomarker_diagnosis_ns hsa-mir-375 "Diabetes Mellitus, Type 1" 28986402 "Regarding circulating miRNAs, 11 were consistently dysregulated in T1DM patients compared to controls: miR-21-5p, miR-24-3p, miR-100-5p, miR-146a-5p, miR-148a-3p, miR-150-5p, miR-181a-5p, miR-210-5p, miR-342-3p, miR-375 and miR-1275" circulation_biomarker_diagnosis_ns hsa-mir-19b "Leukemia, Myeloid, Acute" 28987820 Transfer of multidrug resistance among acute myeloid leukemia cells via extracellular vesicles and their microRNA cargo. circulation_biomarker_diagnosis_ns hsa-mir-483 Adrenal Cortex Neoplasms 29029450 "we demonstrated that miR483-5p absolute plasma levels in ACC patients are powerful molecular markers that may help in the follow-up of patients after surgery and chemotherapy, and contribute to more accurately classify and predict tumor progression." circulation_biomarker_diagnosis_ns hsa-mir-1 Myocardial Infarction 29030746 Platelet microRNA for predicting acute myocardial infarction. circulation_biomarker_diagnosis_ns hsa-mir-126 Myocardial Infarction 29030746 Platelet microRNA for predicting acute myocardial infarction. circulation_biomarker_diagnosis_ns hsa-mir-150 Myocardial Infarction 29030746 Platelet microRNA for predicting acute myocardial infarction. circulation_biomarker_diagnosis_ns hsa-mir-21 Myocardial Infarction 29030746 Platelet microRNA for predicting acute myocardial infarction. circulation_biomarker_diagnosis_ns hsa-mir-181b Diabetic Cardiomyopathies 29044172 Circulating miR-19b and miR-181b are potential biomarkers for diabetic cardiomyopathy. circulation_biomarker_diagnosis_ns hsa-mir-19b Diabetic Cardiomyopathies 29044172 Circulating miR-19b and miR-181b are potential biomarkers for diabetic cardiomyopathy. circulation_biomarker_diagnosis_ns hsa-mir-155 Hypertension 29057982 Characterization of serum miRNAs as molecular biomarkers for acute Stanford type A aortic dissection diagnosis. circulation_biomarker_diagnosis_ns hsa-mir-19b Acute Myocardial Infarction 29085838 The miRNA Expression Profile in Acute Myocardial Infarct Using Sheep Model with Left Ventricular Assist Device Unloading. circulation_biomarker_diagnosis_ns hsa-mir-1246 Pancreatic Neoplasms 29100367 Plasma exosome miR-196a and miR-1246 are potential indicators of localized pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-196a Pancreatic Neoplasms 29100367 Plasma exosome miR-196a and miR-1246 are potential indicators of localized pancreatic cancer. circulation_biomarker_diagnosis_ns hsa-mir-21 "Adenocarcinoma, Lung" 29103767 Circulating microRNA-339-5p and -21 in plasma as an early detection predictors of lung adenocarcinoma. circulation_biomarker_diagnosis_ns hsa-mir-339 "Adenocarcinoma, Lung" 29103767 Circulating microRNA-339-5p and -21 in plasma as an early detection predictors of lung adenocarcinoma. circulation_biomarker_diagnosis_ns hsa-mir-346 Schizophrenia 29127368 Diagnostic value of blood-derived microRNAs for schizophrenia: results of a meta-analysis and validation. circulation_biomarker_diagnosis_ns hsa-mir-16 Transitional Cell Carcinoma 29141625 MicroRNA profiling of dogs with transitional cell carcinoma of the bladder using blood and urine samples. circulation_biomarker_diagnosis_ns hsa-mir-34a Transitional Cell Carcinoma 29141625 MicroRNA profiling of dogs with transitional cell carcinoma of the bladder using blood and urine samples. circulation_biomarker_diagnosis_ns hsa-mir-126 Hypertension 29186297 "Cardiovascular morbidity is associated with differential expression of myriad miRNAs; miR-21, miR-155, miR-126, miR-146a/b, miR-143/145, miR-223, and miR-221 are the top 9 most reported miRNAs in hypertension and atherosclerotic disease" circulation_biomarker_diagnosis_ns hsa-mir-143 Hypertension 29186297 "Cardiovascular morbidity is associated with differential expression of myriad miRNAs; miR-21, miR-155, miR-126, miR-146a/b, miR-143/145, miR-223, and miR-221 are the top 9 most reported miRNAs in hypertension and atherosclerotic disease" circulation_biomarker_diagnosis_ns hsa-mir-145 Hypertension 29186297 "Cardiovascular morbidity is associated with differential expression of myriad miRNAs; miR-21, miR-155, miR-126, miR-146a/b, miR-143/145, miR-223, and miR-221 are the top 9 most reported miRNAs in hypertension and atherosclerotic disease" circulation_biomarker_diagnosis_ns hsa-mir-146a Hypertension 29186297 "Cardiovascular morbidity is associated with differential expression of myriad miRNAs; miR-21, miR-155, miR-126, miR-146a/b, miR-143/145, miR-223, and miR-221 are the top 9 most reported miRNAs in hypertension and atherosclerotic disease" circulation_biomarker_diagnosis_ns hsa-mir-146b Hypertension 29186297 "Cardiovascular morbidity is associated with differential expression of myriad miRNAs; miR-21, miR-155, miR-126, miR-146a/b, miR-143/145, miR-223, and miR-221 are the top 9 most reported miRNAs in hypertension and atherosclerotic disease" circulation_biomarker_diagnosis_ns hsa-mir-155 Hypertension 29186297 "Cardiovascular morbidity is associated with differential expression of myriad miRNAs; miR-21, miR-155, miR-126, miR-146a/b, miR-143/145, miR-223, and miR-221 are the top 9 most reported miRNAs in hypertension and atherosclerotic disease" circulation_biomarker_diagnosis_ns hsa-mir-21 Hypertension 29186297 "Cardiovascular morbidity is associated with differential expression of myriad miRNAs; miR-21, miR-155, miR-126, miR-146a/b, miR-143/145, miR-223, and miR-221 are the top 9 most reported miRNAs in hypertension and atherosclerotic disease" circulation_biomarker_diagnosis_ns hsa-mir-221 Hypertension 29186297 "Cardiovascular morbidity is associated with differential expression of myriad miRNAs; miR-21, miR-155, miR-126, miR-146a/b, miR-143/145, miR-223, and miR-221 are the top 9 most reported miRNAs in hypertension and atherosclerotic disease" circulation_biomarker_diagnosis_ns hsa-mir-223 Hypertension 29186297 "Cardiovascular morbidity is associated with differential expression of myriad miRNAs; miR-21, miR-155, miR-126, miR-146a/b, miR-143/145, miR-223, and miR-221 are the top 9 most reported miRNAs in hypertension and atherosclerotic disease" circulation_biomarker_diagnosis_ns hsa-mir-21 Myocardial Infarction 29188800 Chip-based digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction patients circulation_biomarker_diagnosis_ns hsa-mir-499 Myocardial Infarction 29188800 Chip-based digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction patients circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Hepatocellular" 29215815 "Combination of plasma miRNA-21, -26a, and -29a-3p expression could predict early TACE refractoriness in patients with TACE-treated HCC" circulation_biomarker_diagnosis_ns hsa-mir-26a "Carcinoma, Hepatocellular" 29215815 "Combination of plasma miRNA-21, -26a, and -29a-3p expression could predict early TACE refractoriness in patients with TACE-treated HCC" circulation_biomarker_diagnosis_ns hsa-mir-29a "Carcinoma, Hepatocellular" 29215815 "Combination of plasma miRNA-21, -26a, and -29a-3p expression could predict early TACE refractoriness in patients with TACE-treated HCC" circulation_biomarker_diagnosis_ns hsa-mir-145 Multiple Sclerosis 29246612 "miR-145, miR-223 and miR-326 expression profile is a promising diagnostic biomarker for MS and NPSLE, but not for NMOSD" circulation_biomarker_diagnosis_ns hsa-mir-145 Systemic Lupus Erythematosus 29246612 "miR-145, miR-223 and miR-326 expression profile is a promising diagnostic biomarker for MS and NPSLE, but not for NMOSD" circulation_biomarker_diagnosis_ns hsa-mir-223 Multiple Sclerosis 29246612 "miR-145, miR-223 and miR-326 expression profile is a promising diagnostic biomarker for MS and NPSLE, but not for NMOSD" circulation_biomarker_diagnosis_ns hsa-mir-223 Systemic Lupus Erythematosus 29246612 "miR-145, miR-223 and miR-326 expression profile is a promising diagnostic biomarker for MS and NPSLE, but not for NMOSD" circulation_biomarker_diagnosis_ns hsa-mir-326 Multiple Sclerosis 29246612 "miR-145, miR-223 and miR-326 expression profile is a promising diagnostic biomarker for MS and NPSLE, but not for NMOSD" circulation_biomarker_diagnosis_ns hsa-mir-326 Systemic Lupus Erythematosus 29246612 "miR-145, miR-223 and miR-326 expression profile is a promising diagnostic biomarker for MS and NPSLE, but not for NMOSD" circulation_biomarker_diagnosis_ns hsa-mir-223 Prostate Neoplasms 29246734 "A 3-miR (miRNA-223, miRNA-24 and miRNA-375) score was significant to predict patient reclassification" circulation_biomarker_diagnosis_ns hsa-mir-24 Prostate Neoplasms 29246734 "A 3-miR (miRNA-223, miRNA-24 and miRNA-375) score was significant to predict patient reclassification" circulation_biomarker_diagnosis_ns hsa-mir-375 Prostate Neoplasms 29246734 "A 3-miR (miRNA-223, miRNA-24 and miRNA-375) score was significant to predict patient reclassification" circulation_biomarker_diagnosis_ns hsa-mir-146a Heart Failure 29258606 Inflammation-associated microRNA changes in circulating exosomes of heart failure patients circulation_biomarker_diagnosis_ns hsa-mir-16 Heart Failure 29258606 Inflammation-associated microRNA changes in circulating exosomes of heart failure patients circulation_biomarker_diagnosis_ns hsa-mir-1233 "Carcinoma, Renal Cell" 29262564 "Plasmatic miR-210, miR-221 and miR-1233 profile: potential liquid biopsies candidates for renal cell carcinoma" circulation_biomarker_diagnosis_ns hsa-mir-210 "Carcinoma, Renal Cell" 29262564 "Plasmatic miR-210, miR-221 and miR-1233 profile: potential liquid biopsies candidates for renal cell carcinoma" circulation_biomarker_diagnosis_ns hsa-mir-221 "Carcinoma, Renal Cell" 29262564 "Plasmatic miR-210, miR-221 and miR-1233 profile: potential liquid biopsies candidates for renal cell carcinoma" circulation_biomarker_diagnosis_ns hsa-mir-598 Crohn Colitis 29272478 "Two miRNAs (miR-598, miR-642) were consistently different between the patient groups" circulation_biomarker_diagnosis_ns hsa-mir-642 Crohn Colitis 29272478 "Two miRNAs (miR-598, miR-642) were consistently different between the patient groups" circulation_biomarker_diagnosis_ns hsa-mir-145 Endometriosis 29308623 miR-31 and miR-145 as Potential Non-Invasive Regulatory Biomarkers in Patients with Endometriosis circulation_biomarker_diagnosis_ns hsa-mir-31 Endometriosis 29308623 miR-31 and miR-145 as Potential Non-Invasive Regulatory Biomarkers in Patients with Endometriosis circulation_biomarker_diagnosis_ns hsa-mir-106b "Carcinoma, Hepatocellular" 29312570 Serum microRNA signatures and metabolomics have high diagnostic value in hepatocellular carcinoma circulation_biomarker_diagnosis_ns hsa-mir-182 "Carcinoma, Hepatocellular" 29312570 Serum microRNA signatures and metabolomics have high diagnostic value in hepatocellular carcinoma circulation_biomarker_diagnosis_ns hsa-mir-126 Heart Failure 29314582 "A differential modulation of circulating levels of miR-423, -34a, -21-3p, -126, -199 and -30a was found across the aetiology groups" circulation_biomarker_diagnosis_ns hsa-mir-199 Heart Failure 29314582 "A differential modulation of circulating levels of miR-423, -34a, -21-3p, -126, -199 and -30a was found across the aetiology groups" circulation_biomarker_diagnosis_ns hsa-mir-21 Heart Failure 29314582 "A differential modulation of circulating levels of miR-423, -34a, -21-3p, -126, -199 and -30a was found across the aetiology groups" circulation_biomarker_diagnosis_ns hsa-mir-30a Heart Failure 29314582 "A differential modulation of circulating levels of miR-423, -34a, -21-3p, -126, -199 and -30a was found across the aetiology groups" circulation_biomarker_diagnosis_ns hsa-mir-34a Heart Failure 29314582 "A differential modulation of circulating levels of miR-423, -34a, -21-3p, -126, -199 and -30a was found across the aetiology groups" circulation_biomarker_diagnosis_ns hsa-mir-423 Heart Failure 29314582 "A differential modulation of circulating levels of miR-423, -34a, -21-3p, -126, -199 and -30a was found across the aetiology groups" circulation_biomarker_diagnosis_ns hsa-mir-125a "Carcinoma, Hepatocellular" 29333940 "the measurement of serum levels of miR-125a, miR-139, miR-145, and miR-199a can help to differentiate HCC from CHC and LC" circulation_biomarker_diagnosis_ns hsa-mir-139 "Carcinoma, Hepatocellular" 29333940 "the measurement of serum levels of miR-125a, miR-139, miR-145, and miR-200a can help to differentiate HCC from CHC and LC" circulation_biomarker_diagnosis_ns hsa-mir-145 "Carcinoma, Hepatocellular" 29333940 "the measurement of serum levels of miR-125a, miR-139, miR-145, and miR-201a can help to differentiate HCC from CHC and LC" circulation_biomarker_diagnosis_ns hsa-mir-199a "Carcinoma, Hepatocellular" 29333940 "the measurement of serum levels of miR-125a, miR-139, miR-145, and miR-202a can help to differentiate HCC from CHC and LC" circulation_biomarker_diagnosis_ns hsa-mir-1 Acute Coronary Syndrome 29350392 "although most investigated miRs levels differ significantly between patients with ACS and CIE, similar levels of circulating miR-1-3p, miR-133a-3p, miR-133b, and miR-375 were observed; furthermore, we identified several common miRs as possible risk factors for recurrent cardiovascular events" circulation_biomarker_diagnosis_ns hsa-mir-133a Acute Coronary Syndrome 29350392 "although most investigated miRs levels differ significantly between patients with ACS and CIE, similar levels of circulating miR-1-3p, miR-133a-3p, miR-133b, and miR-375 were observed; furthermore, we identified several common miRs as possible risk factors for recurrent cardiovascular events" circulation_biomarker_diagnosis_ns hsa-mir-133b Acute Coronary Syndrome 29350392 "although most investigated miRs levels differ significantly between patients with ACS and CIE, similar levels of circulating miR-1-3p, miR-133a-3p, miR-133b, and miR-375 were observed; furthermore, we identified several common miRs as possible risk factors for recurrent cardiovascular events" circulation_biomarker_diagnosis_ns hsa-mir-375 Acute Coronary Syndrome 29350392 "although most investigated miRs levels differ significantly between patients with ACS and CIE, similar levels of circulating miR-1-3p, miR-133a-3p, miR-133b, and miR-375 were observed; furthermore, we identified several common miRs as possible risk factors for recurrent cardiovascular events" circulation_biomarker_diagnosis_ns hsa-mir-146a Coronary Artery Disease 29357324 Circulating MiR-146a May be a Potential Biomarker of Coronary Heart Disease in Patients with Subclinical Hypothyroidism. circulation_biomarker_diagnosis_ns hsa-mir-375 "Diabetes Mellitus, Type 2" 29373500 Evaluation of Two-Diabetes Related microRNAs Suitability as Earlier Blood Biomarkers for Detecting Prediabetes and type 2 Diabetes Mellitus circulation_biomarker_diagnosis_ns hsa-mir-155 Coronary Artery Disease 29411649 serum miR-155 content may serve as a novel biomarker for evaluating severity of CHD circulation_biomarker_diagnosis_ns hsa-mir-126 Diabetes Mellitus 29452547 Plasma miR-126 and miR-210 levels may be biomarkers for diabetes with or without CAD circulation_biomarker_diagnosis_ns hsa-mir-106a Bicuspid Aortic Valve Disease 29462317 Expression of circulating miR-17 and miR-106a in the BAV root phenotype patients correlates with the severity of aortopathy and the risk of adverse aortic events circulation_biomarker_diagnosis_ns hsa-mir-17 Bicuspid Aortic Valve Disease 29462317 Expression of circulating miR-17 and miR-106a in the BAV root phenotype patients correlates with the severity of aortopathy and the risk of adverse aortic events circulation_biomarker_diagnosis_ns hsa-mir-136 Amyotrophic Lateral Sclerosis 29466830 "Changes in 4 miRNAs (miR-136-3p, miR-30b-5p, miR-331-3p, miR-496) correlated positively and change in 1 miRNA (miR-2110) correlated negatively with changes in clinical parameters in longitudinal analysis" circulation_biomarker_diagnosis_ns hsa-mir-2110 Amyotrophic Lateral Sclerosis 29466830 "Changes in 4 miRNAs (miR-136-3p, miR-30b-5p, miR-331-3p, miR-496) correlated positively and change in 1 miRNA (miR-2110) correlated negatively with changes in clinical parameters in longitudinal analysis" circulation_biomarker_diagnosis_ns hsa-mir-30b Amyotrophic Lateral Sclerosis 29466830 "Changes in 4 miRNAs (miR-136-3p, miR-30b-5p, miR-331-3p, miR-496) correlated positively and change in 1 miRNA (miR-2110) correlated negatively with changes in clinical parameters in longitudinal analysis" circulation_biomarker_diagnosis_ns hsa-mir-331 Amyotrophic Lateral Sclerosis 29466830 "Changes in 4 miRNAs (miR-136-3p, miR-30b-5p, miR-331-3p, miR-496) correlated positively and change in 1 miRNA (miR-2110) correlated negatively with changes in clinical parameters in longitudinal analysis" circulation_biomarker_diagnosis_ns hsa-mir-496 Amyotrophic Lateral Sclerosis 29466830 "Changes in 4 miRNAs (miR-136-3p, miR-30b-5p, miR-331-3p, miR-496) correlated positively and change in 1 miRNA (miR-2110) correlated negatively with changes in clinical parameters in longitudinal analysis" circulation_biomarker_diagnosis_ns hsa-mir-208b Myocardial Infarction 29475914 plasma levels of circulating miR-208b and miR-499 could serve as potential AMI biomarkers circulation_biomarker_diagnosis_ns hsa-mir-499 Myocardial Infarction 29475914 plasma levels of circulating miR-208b and miR-500 could serve as potential AMI biomarkers circulation_biomarker_diagnosis_ns hsa-mir-25 Heart Failure 29499204 "miR-25 expression during different stages of heart disease, offers a new perspective for the role of miR-25 function in heart failure" circulation_biomarker_diagnosis_ns hsa-mir-128 Friedreich Ataxia 29509186 "We found different expression profiles of miRNAs (hsa-miR-128-3p, hsa-miR-625-3p, hsa-miR-130b-5p, hsa-miR-151a-5p, hsa-miR-330-3p, hsa-miR-323a-3p, and hsa-miR-142-3p) between samples from patients and samples from healthy subjects" circulation_biomarker_diagnosis_ns hsa-mir-130b Friedreich Ataxia 29509186 "We found different expression profiles of miRNAs (hsa-miR-128-3p, hsa-miR-625-3p, hsa-miR-130b-5p, hsa-miR-151a-5p, hsa-miR-330-3p, hsa-miR-323a-3p, and hsa-miR-142-3p) between samples from patients and samples from healthy subjects" circulation_biomarker_diagnosis_ns hsa-mir-142 Friedreich Ataxia 29509186 "We found different expression profiles of miRNAs (hsa-miR-128-3p, hsa-miR-625-3p, hsa-miR-130b-5p, hsa-miR-151a-5p, hsa-miR-330-3p, hsa-miR-323a-3p, and hsa-miR-142-3p) between samples from patients and samples from healthy subjects" circulation_biomarker_diagnosis_ns hsa-mir-151a Friedreich Ataxia 29509186 "We found different expression profiles of miRNAs (hsa-miR-128-3p, hsa-miR-625-3p, hsa-miR-130b-5p, hsa-miR-151a-5p, hsa-miR-330-3p, hsa-miR-323a-3p, and hsa-miR-142-3p) between samples from patients and samples from healthy subjects" circulation_biomarker_diagnosis_ns hsa-mir-323a Friedreich Ataxia 29509186 "We found different expression profiles of miRNAs (hsa-miR-128-3p, hsa-miR-625-3p, hsa-miR-130b-5p, hsa-miR-151a-5p, hsa-miR-330-3p, hsa-miR-323a-3p, and hsa-miR-142-3p) between samples from patients and samples from healthy subjects" circulation_biomarker_diagnosis_ns hsa-mir-330 Friedreich Ataxia 29509186 "We found different expression profiles of miRNAs (hsa-miR-128-3p, hsa-miR-625-3p, hsa-miR-130b-5p, hsa-miR-151a-5p, hsa-miR-330-3p, hsa-miR-323a-3p, and hsa-miR-142-3p) between samples from patients and samples from healthy subjects" circulation_biomarker_diagnosis_ns hsa-mir-625 Friedreich Ataxia 29509186 "We found different expression profiles of miRNAs (hsa-miR-128-3p, hsa-miR-625-3p, hsa-miR-130b-5p, hsa-miR-151a-5p, hsa-miR-330-3p, hsa-miR-323a-3p, and hsa-miR-142-3p) between samples from patients and samples from healthy subjects" circulation_biomarker_diagnosis_ns hsa-mir-146a Periodontitis 29517812 MicroRNA-146a and microRNA-155 as novel crevicular fluid biomarkers for periodontitis in non-diabetic and type 2 diabetic patients. circulation_biomarker_diagnosis_ns hsa-mir-155 Periodontitis 29517812 MicroRNA-146a and microRNA-155 as novel crevicular fluid biomarkers for periodontitis in non-diabetic and type 2 diabetic patients. circulation_biomarker_diagnosis_ns hsa-mir-191 "Aortic Aneurysm, Abdominal" 29518510 Expression in Whole Blood Samples of miRNA-191 and miRNA-455-3p in Patients with AAA and Their Relationship to Clinical Outcomes after Endovascular Repair. circulation_biomarker_diagnosis_ns hsa-mir-455 "Aortic Aneurysm, Abdominal" 29518510 Expression in Whole Blood Samples of miRNA-191 and miRNA-455-3p in Patients with AAA and Their Relationship to Clinical Outcomes after Endovascular Repair. circulation_biomarker_diagnosis_ns hsa-mir-128 Multiple Sclerosis 29527713 "Evaluation of serum miR-191-5p, miR-24-3p, miR-128-3p, and miR-376c-3 in multiple sclerosis patients." circulation_biomarker_diagnosis_ns hsa-mir-191 Multiple Sclerosis 29527713 "Evaluation of serum miR-191-5p, miR-24-3p, miR-128-3p, and miR-376c-3 in multiple sclerosis patients." circulation_biomarker_diagnosis_ns hsa-mir-24 Multiple Sclerosis 29527713 "Evaluation of serum miR-191-5p, miR-24-3p, miR-128-3p, and miR-376c-3 in multiple sclerosis patients." circulation_biomarker_diagnosis_ns hsa-mir-376c Multiple Sclerosis 29527713 "Evaluation of serum miR-191-5p, miR-24-3p, miR-128-3p, and miR-376c-3 in multiple sclerosis patients." circulation_biomarker_diagnosis_ns hsa-mir-126 Atherosclerosis 29531852 "A common microRNA profile to different atherosclerotic disease locations was identified, including deregulation of miR-21, miR-30, miR-126, and miR-221-4p" circulation_biomarker_diagnosis_ns hsa-mir-21 Atherosclerosis 29531852 "A common microRNA profile to different atherosclerotic disease locations was identified, including deregulation of miR-21, miR-30, miR-126, and miR-221-3p" circulation_biomarker_diagnosis_ns hsa-mir-221 Atherosclerosis 29531852 "A common microRNA profile to different atherosclerotic disease locations was identified, including deregulation of miR-21, miR-30, miR-126, and miR-221-5p" circulation_biomarker_diagnosis_ns hsa-mir-30 Atherosclerosis 29531852 "A common microRNA profile to different atherosclerotic disease locations was identified, including deregulation of miR-21, miR-30, miR-126, and miR-221-3p" circulation_biomarker_diagnosis_ns hsa-mir-196a Gastric Neoplasms 29535809 circulating miRNA-196a is a novel biomarker for detection of early gastric cancer and its precursor circulation_biomarker_diagnosis_ns hsa-mir-204 Spinal Cord Injuries 29547407 "We identified 4 targeted miRNAs, including mir-204-5p, mir-519d-3p, mir-20b-5p, mir-6838-5p, which may be potential biomarkers for SCI patients" circulation_biomarker_diagnosis_ns hsa-mir-20b Spinal Cord Injuries 29547407 "We identified 4 targeted miRNAs, including mir-204-5p, mir-519d-3p, mir-20b-5p, mir-6838-5p, which may be potential biomarkers for SCI patients" circulation_biomarker_diagnosis_ns hsa-mir-519d Spinal Cord Injuries 29547407 "We identified 4 targeted miRNAs, including mir-204-5p, mir-519d-3p, mir-20b-5p, mir-6838-5p, which may be potential biomarkers for SCI patients" circulation_biomarker_diagnosis_ns hsa-mir-6838 Spinal Cord Injuries 29547407 "We identified 4 targeted miRNAs, including mir-204-5p, mir-519d-3p, mir-20b-5p, mir-6838-5p, which may be potential biomarkers for SCI patients" circulation_biomarker_diagnosis_ns hsa-mir-199a Multiple Sclerosis 29551498 "Analysis of the expression of mir-34a, mir-199a, mir-30c and mir-19a in peripheral blood CD4+T lymphocytes of relapsing-remitting multiple sclerosis patients." circulation_biomarker_diagnosis_ns hsa-mir-19a Multiple Sclerosis 29551498 "Analysis of the expression of mir-34a, mir-199a, mir-30c and mir-19a in peripheral blood CD4+T lymphocytes of relapsing-remitting multiple sclerosis patients." circulation_biomarker_diagnosis_ns hsa-mir-30c Multiple Sclerosis 29551498 "Analysis of the expression of mir-34a, mir-199a, mir-30c and mir-19a in peripheral blood CD4+T lymphocytes of relapsing-remitting multiple sclerosis patients." circulation_biomarker_diagnosis_ns hsa-mir-34a Multiple Sclerosis 29551498 "Analysis of the expression of mir-34a, mir-199a, mir-30c and mir-19a in peripheral blood CD4+T lymphocytes of relapsing-remitting multiple sclerosis patients." circulation_biomarker_diagnosis_ns hsa-mir-143 "Leukemia, Lymphoblastic, Acute, Childhood" 29556721 Clinical utility of miR-143/miR-182 levels in prognosis and risk stratification specificity of BFM-treated childhood acute lymphoblastic leukemia. circulation_biomarker_diagnosis_ns hsa-mir-182 "Leukemia, Lymphoblastic, Acute, Childhood" 29556721 Clinical utility of miR-143/miR-182 levels in prognosis and risk stratification specificity of BFM-treated childhood acute lymphoblastic leukemia. circulation_biomarker_diagnosis_ns hsa-mir-106a "Carcinoma, Breast" 29557526 Circulating microRNAs from the miR-106a-363 cluster on chromosome X as novel diagnostic biomarkers for breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-223 Dementia 29559383 Serum Exosomal miR-223 Serves as a Potential Diagnostic and Prognostic Biomarker for Dementia circulation_biomarker_diagnosis_ns hsa-mir-208a Chagas Disease 29559958 Circulating Plasma MicroRNA-208a as Potential Biomarker of Chronic Indeterminate Phase of Chagas Disease circulation_biomarker_diagnosis_ns hsa-let-7e Dengue Virus Infection 29566761 "six significantly differentially expressed miRNAs, including hsa-miR-184, hsa-let-7e-5p, hsa-miR-132-3p, hsa-miR-155-5p, and hsa-miR-1246, were chosen for RT-qPCR analysis" circulation_biomarker_diagnosis_ns hsa-mir-1246 Dengue Virus Infection 29566761 "six significantly differentially expressed miRNAs, including hsa-miR-184, hsa-let-7e-5p, hsa-miR-132-3p, hsa-miR-155-5p, and hsa-miR-1246, were chosen for RT-qPCR analysis" circulation_biomarker_diagnosis_ns hsa-mir-132 Dengue Virus Infection 29566761 "six significantly differentially expressed miRNAs, including hsa-miR-184, hsa-let-7e-5p, hsa-miR-132-3p, hsa-miR-155-5p, and hsa-miR-1246, were chosen for RT-qPCR analysis" circulation_biomarker_diagnosis_ns hsa-mir-155 Dengue Virus Infection 29566761 "six significantly differentially expressed miRNAs, including hsa-miR-184, hsa-let-7e-5p, hsa-miR-132-3p, hsa-miR-155-5p, and hsa-miR-1246, were chosen for RT-qPCR analysis" circulation_biomarker_diagnosis_ns hsa-mir-184 Dengue Virus Infection 29566761 "six significantly differentially expressed miRNAs, including hsa-miR-184, hsa-let-7e-5p, hsa-miR-132-3p, hsa-miR-155-5p, and hsa-miR-1246, were chosen for RT-qPCR analysis" circulation_biomarker_diagnosis_ns hsa-mir-155 "Leukemia, Myeloid, Acute" 29601851 MicroRNA-155 expression and function in AML: An evolving paradigm. circulation_biomarker_diagnosis_ns hsa-mir-33a "Diabetes Mellitus, Type 2" 29601916 B-RCA revealed circulating miR-33a/b associates with serum cholesterol in type 2 diabetes patients at high risk of ASCVD. circulation_biomarker_diagnosis_ns hsa-mir-33b "Diabetes Mellitus, Type 2" 29601916 B-RCA revealed circulating miR-33a/b associates with serum cholesterol in type 2 diabetes patients at high risk of ASCVD. circulation_biomarker_diagnosis_ns hsa-mir-126 Obesity 29607782 Dysregulation of circulating miRs may contribute mechanistically to the heightened inflammatory state associated with overweight and obesity circulation_biomarker_diagnosis_ns hsa-mir-146a Obesity 29607782 Dysregulation of circulating miRs may contribute mechanistically to the heightened inflammatory state associated with overweight and obesity circulation_biomarker_diagnosis_ns hsa-mir-150 Obesity 29607782 Dysregulation of circulating miRs may contribute mechanistically to the heightened inflammatory state associated with overweight and obesity circulation_biomarker_diagnosis_ns hsa-mir-181b Obesity 29607782 Dysregulation of circulating miRs may contribute mechanistically to the heightened inflammatory state associated with overweight and obesity circulation_biomarker_diagnosis_ns hsa-mir-34a Obesity 29607782 Dysregulation of circulating miRs may contribute mechanistically to the heightened inflammatory state associated with overweight and obesity circulation_biomarker_diagnosis_ns hsa-mir-126 Hypertension 29615793 "Specifically, altered circulating expression of miR-17, miR-21, miR-34a, miR-92a, miR-126, miR-145, miR-146a, and miR-154 has been linked with the pathogenesis and progression of cardiovascular disease" circulation_biomarker_diagnosis_ns hsa-mir-145 Hypertension 29615793 "Specifically, altered circulating expression of miR-17, miR-21, miR-34a, miR-92a, miR-126, miR-145, miR-146a, and miR-155 has been linked with the pathogenesis and progression of cardiovascular disease" circulation_biomarker_diagnosis_ns hsa-mir-146a Hypertension 29615793 "Specifically, altered circulating expression of miR-17, miR-21, miR-34a, miR-92a, miR-126, miR-145, miR-146a, and miR-156 has been linked with the pathogenesis and progression of cardiovascular disease" circulation_biomarker_diagnosis_ns hsa-mir-157 Hypertension 29615793 "Specifically, altered circulating expression of miR-17, miR-21, miR-34a, miR-92a, miR-126, miR-145, miR-146a, and miR-157 has been linked with the pathogenesis and progression of cardiovascular disease" circulation_biomarker_diagnosis_ns hsa-mir-17 Hypertension 29615793 "Specifically, altered circulating expression of miR-17, miR-21, miR-34a, miR-92a, miR-126, miR-145, miR-146a, and miR-150 has been linked with the pathogenesis and progression of cardiovascular disease" circulation_biomarker_diagnosis_ns hsa-mir-21 Hypertension 29615793 "Specifically, altered circulating expression of miR-17, miR-21, miR-34a, miR-92a, miR-126, miR-145, miR-146a, and miR-151 has been linked with the pathogenesis and progression of cardiovascular disease" circulation_biomarker_diagnosis_ns hsa-mir-34a Hypertension 29615793 "Specifically, altered circulating expression of miR-17, miR-21, miR-34a, miR-92a, miR-126, miR-145, miR-146a, and miR-152 has been linked with the pathogenesis and progression of cardiovascular disease" circulation_biomarker_diagnosis_ns hsa-mir-92a Hypertension 29615793 "Specifically, altered circulating expression of miR-17, miR-21, miR-34a, miR-92a, miR-126, miR-145, miR-146a, and miR-153 has been linked with the pathogenesis and progression of cardiovascular disease" circulation_biomarker_diagnosis_ns hsa-mir-3162 Human Immunodeficiency Virus Infection 29627523 mircoRNA-3162-3p is a potential biomarker to identify new infections in HIV-1-infected patients. circulation_biomarker_diagnosis_ns hsa-mir-200c "Leukemia, Lymphoblastic, Acute" 29630744 MicroRNA-326 and microRNA-200c: Two novel biomarkers for diagnosis and prognosis of pediatric acute lymphoblastic leukemia. circulation_biomarker_diagnosis_ns hsa-mir-326 "Leukemia, Lymphoblastic, Acute" 29630744 MicroRNA-326 and microRNA-200c: Two novel biomarkers for diagnosis and prognosis of pediatric acute lymphoblastic leukemia. circulation_biomarker_diagnosis_ns hsa-mir-141 Parkinson Disease 29631008 "Differential expression of miR-34a, miR-141, and miR-9 in MPP+-treated differentiated PC12 cells as a model of Parkinson's disease." circulation_biomarker_diagnosis_ns hsa-mir-34a Parkinson Disease 29631008 "Differential expression of miR-34a, miR-141, and miR-9 in MPP+-treated differentiated PC12 cells as a model of Parkinson's disease." circulation_biomarker_diagnosis_ns hsa-mir-9 Parkinson Disease 29631008 "Differential expression of miR-34a, miR-141, and miR-9 in MPP+-treated differentiated PC12 cells as a model of Parkinson's disease." circulation_biomarker_diagnosis_ns hsa-mir-145 Endometriosis 29633787 miR-31 and miR-145 as Potential Non-Invasive Regulatory Biomarkers in Patients with Endometriosis circulation_biomarker_diagnosis_ns hsa-mir-31 Endometriosis 29633787 miR-31 and miR-145 as Potential Non-Invasive Regulatory Biomarkers in Patients with Endometriosis circulation_biomarker_diagnosis_ns hsa-mir-539 Azoospermia 29635626 a model that included miR-539-5p and miR-941 expression values is also described as being useful for predicting the presence of residual spermatogenesis in individuals with severe spermatogenic disorders with diagnostic accuracy circulation_biomarker_diagnosis_ns hsa-mir-941 Azoospermia 29635626 a model that included miR-539-5p and miR-941 expression values is also described as being useful for predicting the presence of residual spermatogenesis in individuals with severe spermatogenic disorders with diagnostic accuracy circulation_biomarker_diagnosis_ns hsa-mir-122 Liver Diseases [unspecific] 29636028 Comprehensive analysis of blood cells and plasma identifies tissue-specific miRNAs as potential novel circulating biomarkers circulation_biomarker_diagnosis_ns hsa-mir-155 Inflammatory Bowel Diseases 29668922 "Target-based approach (miR-16, miR-21, miR-155, and miR-223) has been used to evaluate miRNA expression" circulation_biomarker_diagnosis_ns hsa-mir-16 Inflammatory Bowel Diseases 29668922 "Target-based approach (miR-16, miR-21, miR-155, and miR-223) has been used to evaluate miRNA expression" circulation_biomarker_diagnosis_ns hsa-mir-21 Inflammatory Bowel Diseases 29668922 "Target-based approach (miR-16, miR-21, miR-155, and miR-223) has been used to evaluate miRNA expression" circulation_biomarker_diagnosis_ns hsa-mir-223 Inflammatory Bowel Diseases 29668922 "Target-based approach (miR-16, miR-21, miR-155, and miR-223) has been used to evaluate miRNA expression" circulation_biomarker_diagnosis_ns hsa-let-7b Amyotrophic Lateral Sclerosis 29670510 "We observed significant aberrant dysregulation across our patient cohort for miR-124a, miR-206, miR-9, let-7b, and miR-638" circulation_biomarker_diagnosis_ns hsa-mir-124a Amyotrophic Lateral Sclerosis 29670510 "We observed significant aberrant dysregulation across our patient cohort for miR-124a, miR-206, miR-9, let-7b, and miR-638" circulation_biomarker_diagnosis_ns hsa-mir-206 Amyotrophic Lateral Sclerosis 29670510 "We observed significant aberrant dysregulation across our patient cohort for miR-124a, miR-206, miR-9, let-7b, and miR-638" circulation_biomarker_diagnosis_ns hsa-mir-638 Amyotrophic Lateral Sclerosis 29670510 "We observed significant aberrant dysregulation across our patient cohort for miR-124a, miR-206, miR-9, let-7b, and miR-638" circulation_biomarker_diagnosis_ns hsa-mir-9 Amyotrophic Lateral Sclerosis 29670510 "We observed significant aberrant dysregulation across our patient cohort for miR-124a, miR-206, miR-9, let-7b, and miR-638" circulation_biomarker_diagnosis_ns hsa-mir-106a "Squamous Cell Carcinoma, Lung" 29673101 "a four-miRNA signature (miR-181a-5p, miR-21-5p, miR-106a-5p, and miR-93-5p) was identified for LSCC detection" circulation_biomarker_diagnosis_ns hsa-mir-181a "Squamous Cell Carcinoma, Lung" 29673101 "a four-miRNA signature (miR-181a-5p, miR-21-5p, miR-106a-5p, and miR-93-5p) was identified for LSCC detection" circulation_biomarker_diagnosis_ns hsa-mir-21 "Squamous Cell Carcinoma, Lung" 29673101 "a four-miRNA signature (miR-181a-5p, miR-21-5p, miR-106a-5p, and miR-93-5p) was identified for LSCC detection" circulation_biomarker_diagnosis_ns hsa-mir-93 "Squamous Cell Carcinoma, Lung" 29673101 "a four-miRNA signature (miR-181a-5p, miR-21-5p, miR-106a-5p, and miR-93-5p) was identified for LSCC detection" circulation_biomarker_diagnosis_ns hsa-let-7a Breast Neoplasms 29683112 "A panel of serum ncRNAs, including let-7a, miR-155, miR-574-5p, and MALAT1, was shown to be present in patients with breast cancer." circulation_biomarker_diagnosis_ns hsa-mir-155 Breast Neoplasms 29683112 "A panel of serum ncRNAs, including let-7a, miR-155, miR-574-5p, and MALAT1, was shown to be present in patients with breast cancer." circulation_biomarker_diagnosis_ns hsa-mir-574 Breast Neoplasms 29683112 "A panel of serum ncRNAs, including let-7a, miR-155, miR-574-5p, and MALAT1, was shown to be present in patients with breast cancer." circulation_biomarker_diagnosis_ns hsa-mir-137 Schizophrenia 29684772 "Identification of miR-22-3p, miR-92a-3p, and miR-137 in peripheral blood as biomarker for schizophrenia" circulation_biomarker_diagnosis_ns hsa-mir-22 Schizophrenia 29684772 "Identification of miR-22-3p, miR-92a-3p, and miR-137 in peripheral blood as biomarker for schizophrenia" circulation_biomarker_diagnosis_ns hsa-mir-92a Schizophrenia 29684772 "Identification of miR-22-3p, miR-92a-3p, and miR-137 in peripheral blood as biomarker for schizophrenia" circulation_biomarker_diagnosis_ns hsa-mir-3613 Liposarcoma 29689704 Whole blood miRNA expression analysis reveals miR-3613-3p as a potential biomarker for dedifferentiated liposarcoma. circulation_biomarker_diagnosis_ns hsa-mir-1 Myocardial Infarction 29698386 "Following the identification of cardiac-specific microRNA miR-208a in circulation, more non-coding RNAs (miR-1, miR-499 and miR-133) have been identified as biomarkers not only for the diagnosis of AMI but also for prognosis post infarction" circulation_biomarker_diagnosis_ns hsa-mir-133 Myocardial Infarction 29698386 "Following the identification of cardiac-specific microRNA miR-208a in circulation, more non-coding RNAs (miR-1, miR-499 and miR-133) have been identified as biomarkers not only for the diagnosis of AMI but also for prognosis post infarction" circulation_biomarker_diagnosis_ns hsa-mir-208a Myocardial Infarction 29698386 "Following the identification of cardiac-specific microRNA miR-208a in circulation, more non-coding RNAs (miR-1, miR-499 and miR-133) have been identified as biomarkers not only for the diagnosis of AMI but also for prognosis post infarction" circulation_biomarker_diagnosis_ns hsa-mir-499 Myocardial Infarction 29698386 "Following the identification of cardiac-specific microRNA miR-208a in circulation, more non-coding RNAs (miR-1, miR-499 and miR-133) have been identified as biomarkers not only for the diagnosis of AMI but also for prognosis post infarction" circulation_biomarker_diagnosis_ns hsa-mir-21 "Leukemia, Lymphocytic, Chronic, B-Cell" 29730931 "specifically miR-21-5p and a 23 nucleotide long 5'-phosphorylated miRNA with 3'-uridylation (iso-miR-16-5p), were only detected in the CLL patients" circulation_biomarker_diagnosis_ns hsa-let-7c Respiratory Syncytial Virus Pneumonia 29733865 "MicroRNA 146-5p, miR-let-7c-5p, miR-221 and miR-345-5p are differentially expressed in Respiratory Syncytial Virus (RSV) persistently infected HEp-2 cells." circulation_biomarker_diagnosis_ns hsa-mir-146 Respiratory Syncytial Virus Pneumonia 29733865 "MicroRNA 146-5p, miR-let-7c-5p, miR-221 and miR-345-5p are differentially expressed in Respiratory Syncytial Virus (RSV) persistently infected HEp-2 cells." circulation_biomarker_diagnosis_ns hsa-mir-221 Respiratory Syncytial Virus Pneumonia 29733865 "MicroRNA 146-5p, miR-let-7c-5p, miR-221 and miR-345-5p are differentially expressed in Respiratory Syncytial Virus (RSV) persistently infected HEp-2 cells." circulation_biomarker_diagnosis_ns hsa-mir-345 Respiratory Syncytial Virus Pneumonia 29733865 "MicroRNA 146-5p, miR-let-7c-5p, miR-221 and miR-345-5p are differentially expressed in Respiratory Syncytial Virus (RSV) persistently infected HEp-2 cells." circulation_biomarker_diagnosis_ns hsa-mir-146a Cerebral Malaria 29747626 "The differential expression profiles of these selected miRNA (miR-146a, miR-150, miR-193b, miR-205, miR-215, miR-467a, and miR-486) were analyzed in mouse MV" circulation_biomarker_diagnosis_ns hsa-mir-150 Cerebral Malaria 29747626 "The differential expression profiles of these selected miRNA (miR-146a, miR-150, miR-193b, miR-205, miR-215, miR-467a, and miR-486) were analyzed in mouse MV" circulation_biomarker_diagnosis_ns hsa-mir-193b Cerebral Malaria 29747626 "The differential expression profiles of these selected miRNA (miR-146a, miR-150, miR-193b, miR-205, miR-215, miR-467a, and miR-486) were analyzed in mouse MV" circulation_biomarker_diagnosis_ns hsa-mir-205 Cerebral Malaria 29747626 "The differential expression profiles of these selected miRNA (miR-146a, miR-150, miR-193b, miR-205, miR-215, miR-467a, and miR-486) were analyzed in mouse MV" circulation_biomarker_diagnosis_ns hsa-mir-215 Cerebral Malaria 29747626 "The differential expression profiles of these selected miRNA (miR-146a, miR-150, miR-193b, miR-205, miR-215, miR-467a, and miR-486) were analyzed in mouse MV" circulation_biomarker_diagnosis_ns hsa-mir-467a Cerebral Malaria 29747626 "The differential expression profiles of these selected miRNA (miR-146a, miR-150, miR-193b, miR-205, miR-215, miR-467a, and miR-486) were analyzed in mouse MV" circulation_biomarker_diagnosis_ns hsa-mir-486 Cerebral Malaria 29747626 "The differential expression profiles of these selected miRNA (miR-146a, miR-150, miR-193b, miR-205, miR-215, miR-467a, and miR-486) were analyzed in mouse MV" circulation_biomarker_diagnosis_ns hsa-mir-106a Proliferative Glomerulonephritis 29748623 Plasma microRNA panel is a novel biomarker for focal segmental glomerulosclerosis and associated with podocyte apoptosis. circulation_biomarker_diagnosis_ns hsa-mir-1229 Colorectal Carcinoma 29780253 "A 5-serum miRNA panel (miRNA-1246, miRNA-202-3p, miRNA-21-3p, miRNA-1229-3p, and miRNA-532-3p) effectively distinguished CRCs from HCs" circulation_biomarker_diagnosis_ns hsa-mir-1246 Colorectal Carcinoma 29780253 "A 5-serum miRNA panel (miRNA-1246, miRNA-202-3p, miRNA-21-3p, miRNA-1229-3p, and miRNA-532-3p) effectively distinguished CRCs from HCs" circulation_biomarker_diagnosis_ns hsa-mir-202 Colorectal Carcinoma 29780253 "A 5-serum miRNA panel (miRNA-1246, miRNA-202-3p, miRNA-21-3p, miRNA-1229-3p, and miRNA-532-3p) effectively distinguished CRCs from HCs" circulation_biomarker_diagnosis_ns hsa-mir-21 Colorectal Carcinoma 29780253 "A 5-serum miRNA panel (miRNA-1246, miRNA-202-3p, miRNA-21-3p, miRNA-1229-3p, and miRNA-532-3p) effectively distinguished CRCs from HCs" circulation_biomarker_diagnosis_ns hsa-mir-532 Colorectal Carcinoma 29780253 "A 5-serum miRNA panel (miRNA-1246, miRNA-202-3p, miRNA-21-3p, miRNA-1229-3p, and miRNA-532-3p) effectively distinguished CRCs from HCs" circulation_biomarker_diagnosis_ns hsa-mir-451 Pulmonary Hypertension 29795360 Plasma miR-451 with echocardiography serves as a diagnostic reference for pulmonary hypertension. circulation_biomarker_diagnosis_ns hsa-let-7a Diabetic Retinopathy 29812988 "a panel of three miRNAs (hsa-let-7a-5p, hsa-miR-novel-chr5_15976, and hsa-miR-28-3p) presented 0.92 sensitivity and 0.94 specificity for distinguishing T2DM-DR from T2DM-no-DR" circulation_biomarker_diagnosis_ns hsa-mir-28 Diabetic Retinopathy 29812988 "a panel of three miRNAs (hsa-let-7a-5p, hsa-miR-novel-chr5_15976, and hsa-miR-28-3p) presented 0.92 sensitivity and 0.94 specificity for distinguishing T2DM-DR from T2DM-no-DR" circulation_biomarker_diagnosis_ns hsa-mir-93 Uterine Cancer 29844841 Expression of serum Hsa-miR-93 in uterine cancer and its clinical significance. circulation_biomarker_diagnosis_ns hsa-mir-192 Diabetic Nephropathy 29845236 Expression of microRNA?377 and microRNA?192 and their potential as blood?based biomarkers for early detection of type 2 diabetic nephropathy. circulation_biomarker_diagnosis_ns hsa-mir-377 Diabetic Nephropathy 29845236 Expression of microRNA?377 and microRNA?192 and their potential as blood?based biomarkers for early detection of type 2 diabetic nephropathy. circulation_biomarker_diagnosis_ns hsa-mir-29b Endometrial Neoplasms 29848072 Expression and prognostic value of miRNA-29b in peripheral blood for endometrial cancer. circulation_biomarker_diagnosis_ns hsa-mir-21 Atrial Fibrillation 29848477 Circulating MicroRNA-21 Correlates With Left Atrial Low-Voltage Areas and Is Associated With Procedure Outcome in Patients Undergoing Atrial Fibrillation Ablation. circulation_biomarker_diagnosis_ns hsa-mir-503 Coronary Artery Disease 29870767 The relationship of plasma miR-503 and coronary collateral circulation in patients with coronary artery disease. circulation_biomarker_diagnosis_ns hsa-mir-122 Chronic Hepatitis B 29881991 Plasma miRNA-122-5p and miRNA-151a-3p identified as potential biomarkers for liver injury among CHB patients with PNALT. circulation_biomarker_diagnosis_ns hsa-mir-151a Chronic Hepatitis B 29881991 Plasma miRNA-122-5p and miRNA-151a-3p identified as potential biomarkers for liver injury among CHB patients with PNALT. circulation_biomarker_diagnosis_ns hsa-mir-107 Alzheimer Disease 29885309 "Only six of these were consistent in their direction of expression between studies (miR-107, miR-125b, miR-146a, miR-181c, miR-29b, and miR-342), and they were all shown to be down regulated in individuals with AD compared to controls" circulation_biomarker_diagnosis_ns hsa-mir-125b Alzheimer Disease 29885309 "Only six of these were consistent in their direction of expression between studies (miR-107, miR-125b, miR-146a, miR-181c, miR-29b, and miR-342), and they were all shown to be down regulated in individuals with AD compared to controls" circulation_biomarker_diagnosis_ns hsa-mir-146a Alzheimer Disease 29885309 "Only six of these were consistent in their direction of expression between studies (miR-107, miR-125b, miR-146a, miR-181c, miR-29b, and miR-342), and they were all shown to be down regulated in individuals with AD compared to controls" circulation_biomarker_diagnosis_ns hsa-mir-181c Alzheimer Disease 29885309 "Only six of these were consistent in their direction of expression between studies (miR-107, miR-125b, miR-146a, miR-181c, miR-29b, and miR-342), and they were all shown to be down regulated in individuals with AD compared to controls" circulation_biomarker_diagnosis_ns hsa-mir-29b Alzheimer Disease 29885309 "Only six of these were consistent in their direction of expression between studies (miR-107, miR-125b, miR-146a, miR-181c, miR-29b, and miR-342), and they were all shown to be down regulated in individuals with AD compared to controls" circulation_biomarker_diagnosis_ns hsa-mir-342 Alzheimer Disease 29885309 "Only six of these were consistent in their direction of expression between studies (miR-107, miR-125b, miR-146a, miR-181c, miR-29b, and miR-342), and they were all shown to be down regulated in individuals with AD compared to controls" circulation_biomarker_diagnosis_ns hsa-mir-509 Congenital Heart Diseases 29890280 Clinical diagnostic value of circulating serum miR-509-3p in pulmonary arterial hypertension with congenital heart disease. circulation_biomarker_diagnosis_ns hsa-mir-16 Rheumatoid Arthritis 29892977 Circulating serum miR-223-3p and miR-16-5p as possible biomarkers of early rheumatoid arthritis. circulation_biomarker_diagnosis_ns hsa-mir-223 Rheumatoid Arthritis 29892977 Circulating serum miR-223-3p and miR-16-5p as possible biomarkers of early rheumatoid arthritis. circulation_biomarker_diagnosis_ns hsa-mir-17 Endometriosis 29901577 "the present study characterizes the role of miR-17, IL-4, and IL-6 in the pathogenesis of endometriosis, suggesting the feasibility of using miR-17 and selected cytokines as a noninvasive diagnostic test for the detection of endometriosis" circulation_biomarker_diagnosis_ns hsa-mir-126 Diabetic Nephropathy 29902497 "6 miRNAs were consistently dysregulated in DKD patients compared to controls: miR-21-5p, miR-29a-3p, miR-126-3p, miR-192-5p, miR-214-3p, and miR-342-3p" circulation_biomarker_diagnosis_ns hsa-mir-192 Diabetic Nephropathy 29902497 "6 miRNAs were consistently dysregulated in DKD patients compared to controls: miR-21-5p, miR-29a-3p, miR-126-3p, miR-192-5p, miR-214-3p, and miR-342-3p" circulation_biomarker_diagnosis_ns hsa-mir-21 Diabetic Nephropathy 29902497 "6 miRNAs were consistently dysregulated in DKD patients compared to controls: miR-21-5p, miR-29a-3p, miR-126-3p, miR-192-5p, miR-214-3p, and miR-342-3p" circulation_biomarker_diagnosis_ns hsa-mir-214 Diabetic Nephropathy 29902497 "6 miRNAs were consistently dysregulated in DKD patients compared to controls: miR-21-5p, miR-29a-3p, miR-126-3p, miR-192-5p, miR-214-3p, and miR-342-3p" circulation_biomarker_diagnosis_ns hsa-mir-29a Diabetic Nephropathy 29902497 "6 miRNAs were consistently dysregulated in DKD patients compared to controls: miR-21-5p, miR-29a-3p, miR-126-3p, miR-192-5p, miR-214-3p, and miR-342-3p" circulation_biomarker_diagnosis_ns hsa-mir-342 Diabetic Nephropathy 29902497 "6 miRNAs were consistently dysregulated in DKD patients compared to controls: miR-21-5p, miR-29a-3p, miR-126-3p, miR-192-5p, miR-214-3p, and miR-342-3p" circulation_biomarker_diagnosis_ns hsa-mir-215 Osteosarcoma 29907935 Circulating miR-215-5p and miR-642a-5p as potential biomarker for diagnosis of osteosarcoma in Mexican population. circulation_biomarker_diagnosis_ns hsa-mir-642a Osteosarcoma 29907935 Circulating miR-215-5p and miR-642a-5p as potential biomarker for diagnosis of osteosarcoma in Mexican population. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Pancreatic" 29922178 the diagnostic value of miR-21 in PA was also demonstrated by the pooled sensitivity circulation_biomarker_diagnosis_ns hsa-mir-122 Primary Sclerosing Cholangitis 29922759 Serum miRNA-122 is an independent biomarker of survival in patients with primary sclerosing cholangitis. circulation_biomarker_diagnosis_ns hsa-let-7a Gastric Neoplasms 29923196 "deregulation of several circulating miRNAs (i.e., let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer)" circulation_biomarker_diagnosis_ns hsa-mir-100 Esophageal Neoplasms 29923196 "deregulation of several circulating miRNAs (i.e., let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer)" circulation_biomarker_diagnosis_ns hsa-mir-10b Gastric Neoplasms 29923196 "deregulation of several circulating miRNAs (i.e., let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer)" circulation_biomarker_diagnosis_ns hsa-mir-151a Esophageal Neoplasms 29923196 "deregulation of several circulating miRNAs (i.e., let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer)" circulation_biomarker_diagnosis_ns hsa-mir-18a Gastric Neoplasms 29923196 "deregulation of several circulating miRNAs (i.e., let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer)" circulation_biomarker_diagnosis_ns hsa-mir-192a Gastric Neoplasms 29923196 "deregulation of several circulating miRNAs (i.e., let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer)" circulation_biomarker_diagnosis_ns hsa-mir-21 Esophageal Neoplasms 29923196 "deregulation of several circulating miRNAs (i.e., let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer)" circulation_biomarker_diagnosis_ns hsa-mir-21 Gastric Neoplasms 29923196 "deregulation of several circulating miRNAs (i.e., let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer)" circulation_biomarker_diagnosis_ns hsa-mir-25 Esophageal Neoplasms 29923196 "deregulation of several circulating miRNAs (i.e., let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer)" circulation_biomarker_diagnosis_ns hsa-mir-375 Esophageal Neoplasms 29923196 "deregulation of several circulating miRNAs (i.e., let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer)" circulation_biomarker_diagnosis_ns hsa-mir-93 Gastric Neoplasms 29923196 "deregulation of several circulating miRNAs (i.e., let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer)" circulation_biomarker_diagnosis_ns hsa-mir-106a Gastric Neoplasms 29929476 "circulating miR-21, miR-93, miR-106a and miR-106b could be used as diagnostic plasma biomarkers in gastric cancer patients" circulation_biomarker_diagnosis_ns hsa-mir-106b Gastric Neoplasms 29929476 "circulating miR-21, miR-93, miR-106a and miR-106b could be used as diagnostic plasma biomarkers in gastric cancer patients" circulation_biomarker_diagnosis_ns hsa-mir-21 Gastric Neoplasms 29929476 "circulating miR-21, miR-93, miR-106a and miR-106b could be used as diagnostic plasma biomarkers in gastric cancer patients" circulation_biomarker_diagnosis_ns hsa-mir-93 Gastric Neoplasms 29929476 "circulating miR-21, miR-93, miR-106a and miR-106b could be used as diagnostic plasma biomarkers in gastric cancer patients" circulation_biomarker_diagnosis_ns hsa-mir-21 Gastric Neoplasms 29936770 Clinical application value of combined detection of serum miR-378 and miR-21 in gastric cancer circulation_biomarker_diagnosis_ns hsa-mir-378 Gastric Neoplasms 29936770 Clinical application value of combined detection of serum miR-378 and miR-21 in gastric cancer circulation_biomarker_diagnosis_ns hsa-mir-146b Asthma 29940952 "Stepwise logistic regression yielded a 3-microRNA model (miR-146b, miR-206 and miR-720) that, combined with the exacerbation clinical score, had excellent predictive power with a 0.81 AUROC" circulation_biomarker_diagnosis_ns hsa-mir-206 Asthma 29940952 "Stepwise logistic regression yielded a 3-microRNA model (miR-146b, miR-206 and miR-720) that, combined with the exacerbation clinical score, had excellent predictive power with a 0.81 AUROC" circulation_biomarker_diagnosis_ns hsa-mir-720 Asthma 29940952 "Stepwise logistic regression yielded a 3-microRNA model (miR-146b, miR-206 and miR-720) that, combined with the exacerbation clinical score, had excellent predictive power with a 0.81 AUROC" circulation_biomarker_diagnosis_ns hsa-mir-338 Colorectal Carcinoma 29952077 Circulating miR-338-5p is a potential diagnostic biomarker in colorectal cancer. circulation_biomarker_diagnosis_ns hsa-mir-146a Pulmonary Sarcoidosis 29956871 "Our data provide evidence that exosomes and microvesicles as extracellular vesicles are present in the bronchoalveolar space of sarcoidosis patients and they differentially express EV miRNA (miR-146a and miR-150), the expression of which correlates negatively with pulmonary function indices" circulation_biomarker_diagnosis_ns hsa-mir-150 Pulmonary Sarcoidosis 29956871 "Our data provide evidence that exosomes and microvesicles as extracellular vesicles are present in the bronchoalveolar space of sarcoidosis patients and they differentially express EV miRNA (miR-146a and miR-150), the expression of which correlates negatively with pulmonary function indices" circulation_biomarker_diagnosis_ns hsa-mir-10a "Carcinoma, Hepatocellular" 29962816 "The four serum miRNAs (miR-375, miR-10a, miR-122 and miR-423) could potentially serve as novel biomarkers for the diagnostic and prognostic of HCC" circulation_biomarker_diagnosis_ns hsa-mir-122 "Carcinoma, Hepatocellular" 29962816 "The four serum miRNAs (miR-375, miR-10a, miR-122 and miR-423) could potentially serve as novel biomarkers for the diagnostic and prognostic of HCC" circulation_biomarker_diagnosis_ns hsa-mir-375 "Carcinoma, Hepatocellular" 29962816 "The four serum miRNAs (miR-375, miR-10a, miR-122 and miR-423) could potentially serve as novel biomarkers for the diagnostic and prognostic of HCC" circulation_biomarker_diagnosis_ns hsa-mir-423 "Carcinoma, Hepatocellular" 29962816 "The four serum miRNAs (miR-375, miR-10a, miR-122 and miR-423) could potentially serve as novel biomarkers for the diagnostic and prognostic of HCC" circulation_biomarker_diagnosis_ns hsa-let-7i Traumatic Brain Injury 29963002 "Promising miRNAs such as miR-21, miR-16 or let-7i were identified as suitable candidate biomarkers for TBI" circulation_biomarker_diagnosis_ns hsa-mir-16 Traumatic Brain Injury 29963002 "Promising miRNAs such as miR-21, miR-16 or let-7i were identified as suitable candidate biomarkers for TBI" circulation_biomarker_diagnosis_ns hsa-mir-21 Traumatic Brain Injury 29963002 "Promising miRNAs such as miR-21, miR-16 or let-7i were identified as suitable candidate biomarkers for TBI" circulation_biomarker_diagnosis_ns hsa-mir-125a Lupus Nephritis 29963250 "mir-125a-5p, miR-146a-5p, and mir-221-3p were found to be statistically significant not only in the screening study but also in the real-time qPCR verification studies" circulation_biomarker_diagnosis_ns hsa-mir-146a Lupus Nephritis 29963250 "mir-125a-5p, miR-146a-5p, and mir-221-3p were found to be statistically significant not only in the screening study but also in the real-time qPCR verification studies" circulation_biomarker_diagnosis_ns hsa-mir-221 Lupus Nephritis 29963250 "mir-125a-5p, miR-146a-5p, and mir-221-3p were found to be statistically significant not only in the screening study but also in the real-time qPCR verification studies" circulation_biomarker_diagnosis_ns hsa-mir-652 "Leukemia, Lymphoblastic, Acute" 29967774 Expression of miR-652-3p and Effect on Apoptosis and Drug Sensitivity in Pediatric Acute Lymphoblastic Leukemia. circulation_biomarker_diagnosis_ns hsa-mir-146a Rheumatoid Arthritis 29968332 MiR-146a levels in rheumatoid arthritis and their correlation with disease activity: a meta-analysis. circulation_biomarker_diagnosis_ns hsa-mir-100 Recurrent Spontaneous Abortion 29973278 "Circulating miR-23a-3p, miR-27a-3p, miR-29a-3p, miR-100-5p, miR-127-3p and miR-486-5 might be involved in RM pathogenesis and present potential diagnostic biomarkers for RM" circulation_biomarker_diagnosis_ns hsa-mir-127 Recurrent Spontaneous Abortion 29973278 "Circulating miR-23a-3p, miR-27a-3p, miR-29a-3p, miR-100-5p, miR-127-3p and miR-486-5 might be involved in RM pathogenesis and present potential diagnostic biomarkers for RM" circulation_biomarker_diagnosis_ns hsa-mir-23a Recurrent Spontaneous Abortion 29973278 "Circulating miR-23a-3p, miR-27a-3p, miR-29a-3p, miR-100-5p, miR-127-3p and miR-486-5 might be involved in RM pathogenesis and present potential diagnostic biomarkers for RM" circulation_biomarker_diagnosis_ns hsa-mir-27a Recurrent Spontaneous Abortion 29973278 "Circulating miR-23a-3p, miR-27a-3p, miR-29a-3p, miR-100-5p, miR-127-3p and miR-486-5 might be involved in RM pathogenesis and present potential diagnostic biomarkers for RM" circulation_biomarker_diagnosis_ns hsa-mir-29a Recurrent Spontaneous Abortion 29973278 "Circulating miR-23a-3p, miR-27a-3p, miR-29a-3p, miR-100-5p, miR-127-3p and miR-486-5 might be involved in RM pathogenesis and present potential diagnostic biomarkers for RM" circulation_biomarker_diagnosis_ns hsa-mir-486 Recurrent Spontaneous Abortion 29973278 "Circulating miR-23a-3p, miR-27a-3p, miR-29a-3p, miR-100-5p, miR-127-3p and miR-486-5 might be involved in RM pathogenesis and present potential diagnostic biomarkers for RM" circulation_biomarker_diagnosis_ns hsa-let-7b Graves Disease 29976201 Serum and thyroid tissue level of let-7b and their correlation with TRAb in Graves' disease. circulation_biomarker_diagnosis_ns hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 29976637 Pre-operative Plasma miR-21-5p Is a Sensitive Biomarker and Independent Prognostic Factor in Patients with Pancreatic Ductal Adenocarcinoma Undergoing Surgical Resection. circulation_biomarker_diagnosis_ns hsa-mir-411 "Carcinoma, Lung, Non-Small-Cell" 29976955 "miR-411-5p edited in position 5 was significantly dysregulated in tissues as well as in exosomes of NSCLC patients, suggesting a potential targetome shift relevant to lung cancer biology" circulation_biomarker_diagnosis_ns hsa-mir-19b "Lymphoma, Large B-Cell, Diffuse" 29977116 "miR-19b, miR-20a, and miR-451 could enable to differentiate, at the remission review, patients with residual tumor, from patients with complete remission." circulation_biomarker_diagnosis_ns hsa-mir-20a "Lymphoma, Large B-Cell, Diffuse" 29977116 "miR-19b, miR-20a, and miR-451 could enable to differentiate, at the remission review, patients with residual tumor, from patients with complete remission." circulation_biomarker_diagnosis_ns hsa-mir-451 "Lymphoma, Large B-Cell, Diffuse" 29977116 "miR-19b, miR-20a, and miR-451 could enable to differentiate, at the remission review, patients with residual tumor, from patients with complete remission." circulation_biomarker_diagnosis_ns hsa-mir-155 "Carcinoma, Breast" 29981251 "the serum levels of c-miR16, c-miR21, c-miR155, and c-miR195 could be used as biomarkers to improve the early diagnosis of breast cancer" circulation_biomarker_diagnosis_ns hsa-mir-16 "Carcinoma, Breast" 29981251 "the serum levels of c-miR16, c-miR21, c-miR155, and c-miR195 could be used as biomarkers to improve the early diagnosis of breast cancer" circulation_biomarker_diagnosis_ns hsa-mir-195 "Carcinoma, Breast" 29981251 "the serum levels of c-miR16, c-miR21, c-miR155, and c-miR195 could be used as biomarkers to improve the early diagnosis of breast cancer" circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Breast" 29981251 "the serum levels of c-miR16, c-miR21, c-miR155, and c-miR195 could be used as biomarkers to improve the early diagnosis of breast cancer" circulation_biomarker_diagnosis_ns hsa-mir-190 "Carcinoma, Breast" 29996899 "A combination of of miR-21, miR-23b and miR-190 showe higher sensitivity and specificity in ROC analyses compared to each miRNA alone" circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Breast" 29996899 "A combination of of miR-21, miR-23b and miR-190 showe higher sensitivity and specificity in ROC analyses compared to each miRNA alone" circulation_biomarker_diagnosis_ns hsa-mir-23b "Carcinoma, Breast" 29996899 "A combination of of miR-21, miR-23b and miR-190 showe higher sensitivity and specificity in ROC analyses compared to each miRNA alone" circulation_biomarker_diagnosis_ns hsa-mir-150 "Carcinoma, Hepatocellular" 30003924 Role of circulating miR-182 and miR-150 as biomarkers for cirrhosis and hepatocellular carcinoma post HCV infection in Egyptian patients. circulation_biomarker_diagnosis_ns hsa-mir-182 "Carcinoma, Hepatocellular" 30003924 Role of circulating miR-182 and miR-150 as biomarkers for cirrhosis and hepatocellular carcinoma post HCV infection in Egyptian patients. circulation_biomarker_diagnosis_ns hsa-mir-122 "Fatty Liver, Non-Alcoholic" 30006517 "we have re-examined the predictive value of these serum microRNAs and found that 9 of them (miR-34a, -192, -27b, -122, -22, -21, -197, -30c and -16) associated to NAFLD severity in our independent cohort" circulation_biomarker_diagnosis_ns hsa-mir-16 "Fatty Liver, Non-Alcoholic" 30006517 "we have re-examined the predictive value of these serum microRNAs and found that 9 of them (miR-34a, -192, -27b, -122, -22, -21, -197, -30c and -16) associated to NAFLD severity in our independent cohort" circulation_biomarker_diagnosis_ns hsa-mir-192 "Fatty Liver, Non-Alcoholic" 30006517 "we have re-examined the predictive value of these serum microRNAs and found that 9 of them (miR-34a, -192, -27b, -122, -22, -21, -197, -30c and -16) associated to NAFLD severity in our independent cohort" circulation_biomarker_diagnosis_ns hsa-mir-197 "Fatty Liver, Non-Alcoholic" 30006517 "we have re-examined the predictive value of these serum microRNAs and found that 9 of them (miR-34a, -192, -27b, -122, -22, -21, -197, -30c and -16) associated to NAFLD severity in our independent cohort" circulation_biomarker_diagnosis_ns hsa-mir-21 "Fatty Liver, Non-Alcoholic" 30006517 "we have re-examined the predictive value of these serum microRNAs and found that 9 of them (miR-34a, -192, -27b, -122, -22, -21, -197, -30c and -16) associated to NAFLD severity in our independent cohort" circulation_biomarker_diagnosis_ns hsa-mir-22 "Fatty Liver, Non-Alcoholic" 30006517 "we have re-examined the predictive value of these serum microRNAs and found that 9 of them (miR-34a, -192, -27b, -122, -22, -21, -197, -30c and -16) associated to NAFLD severity in our independent cohort" circulation_biomarker_diagnosis_ns hsa-mir-27b "Fatty Liver, Non-Alcoholic" 30006517 "we have re-examined the predictive value of these serum microRNAs and found that 9 of them (miR-34a, -192, -27b, -122, -22, -21, -197, -30c and -16) associated to NAFLD severity in our independent cohort" circulation_biomarker_diagnosis_ns hsa-mir-30c "Fatty Liver, Non-Alcoholic" 30006517 "we have re-examined the predictive value of these serum microRNAs and found that 9 of them (miR-34a, -192, -27b, -122, -22, -21, -197, -30c and -16) associated to NAFLD severity in our independent cohort" circulation_biomarker_diagnosis_ns hsa-mir-34a "Fatty Liver, Non-Alcoholic" 30006517 "we have re-examined the predictive value of these serum microRNAs and found that 9 of them (miR-34a, -192, -27b, -122, -22, -21, -197, -30c and -16) associated to NAFLD severity in our independent cohort" circulation_biomarker_diagnosis_ns hsa-let-7a "Cardiomyopathy, Dilated" 30008018 "Among the candidates, let-7a-5p, miR-142-3p, miR-145-5p and miR-454-3p levels were significantly increased in LMNAMUT carriers compared to LMNAWT controls and iDCM patients" circulation_biomarker_diagnosis_ns hsa-mir-142 "Cardiomyopathy, Dilated" 30008018 "Among the candidates, let-7a-5p, miR-142-3p, miR-145-5p and miR-454-3p levels were significantly increased in LMNAMUT carriers compared to LMNAWT controls and iDCM patients" circulation_biomarker_diagnosis_ns hsa-mir-145 "Cardiomyopathy, Dilated" 30008018 "Among the candidates, let-7a-5p, miR-142-3p, miR-145-5p and miR-454-3p levels were significantly increased in LMNAMUT carriers compared to LMNAWT controls and iDCM patients" circulation_biomarker_diagnosis_ns hsa-mir-454 "Cardiomyopathy, Dilated" 30008018 "Among the candidates, let-7a-5p, miR-142-3p, miR-145-5p and miR-454-3p levels were significantly increased in LMNAMUT carriers compared to LMNAWT controls and iDCM patients" circulation_biomarker_diagnosis_ns hsa-mir-150 Diabetic Retinopathy 30008390 "Our data suggest a role for miR-150-5p, miR-21-3p and miR-30b-5p as potential biomarkers of the onset of diabetic retinopathy" circulation_biomarker_diagnosis_ns hsa-mir-21 Diabetic Retinopathy 30008390 "Our data suggest a role for miR-150-5p, miR-21-3p and miR-30b-5p as potential biomarkers of the onset of diabetic retinopathy" circulation_biomarker_diagnosis_ns hsa-mir-30b Diabetic Retinopathy 30008390 "Our data suggest a role for miR-150-5p, miR-21-3p and miR-30b-5p as potential biomarkers of the onset of diabetic retinopathy" circulation_biomarker_diagnosis_ns hsa-let-7b Pulmonary Hypertension 30013141 "dysregulations in miRNAs let-7b-5p, -7c-5p, miR-1307-3p, -185-3p, -8084, -331-3p and -210-3p may be detrimental for the development and function of the lungs and pulmonary vasculature" circulation_biomarker_diagnosis_ns hsa-let-7c Pulmonary Hypertension 30013141 "dysregulations in miRNAs let-7b-5p, -7c-5p, miR-1307-3p, -185-3p, -8084, -331-3p and -210-3p may be detrimental for the development and function of the lungs and pulmonary vasculature" circulation_biomarker_diagnosis_ns hsa-mir-1307 Pulmonary Hypertension 30013141 "dysregulations in miRNAs let-7b-5p, -7c-5p, miR-1307-3p, -185-3p, -8084, -331-3p and -210-3p may be detrimental for the development and function of the lungs and pulmonary vasculature" circulation_biomarker_diagnosis_ns hsa-mir-185 Pulmonary Hypertension 30013141 "dysregulations in miRNAs let-7b-5p, -7c-5p, miR-1307-3p, -185-3p, -8084, -331-3p and -210-3p may be detrimental for the development and function of the lungs and pulmonary vasculature" circulation_biomarker_diagnosis_ns hsa-mir-210 Pulmonary Hypertension 30013141 "dysregulations in miRNAs let-7b-5p, -7c-5p, miR-1307-3p, -185-3p, -8084, -331-3p and -210-3p may be detrimental for the development and function of the lungs and pulmonary vasculature" circulation_biomarker_diagnosis_ns hsa-mir-331 Pulmonary Hypertension 30013141 "dysregulations in miRNAs let-7b-5p, -7c-5p, miR-1307-3p, -185-3p, -8084, -331-3p and -210-3p may be detrimental for the development and function of the lungs and pulmonary vasculature" circulation_biomarker_diagnosis_ns hsa-mir-8084 Pulmonary Hypertension 30013141 "dysregulations in miRNAs let-7b-5p, -7c-5p, miR-1307-3p, -185-3p, -8084, -331-3p and -210-3p may be detrimental for the development and function of the lungs and pulmonary vasculature" circulation_biomarker_diagnosis_ns hsa-mir-18a Cystic Fibrosis 30014495 Expression levels of serum miR-18a-5p were correlated with increasing hepatic fibrosis stage in CFLD circulation_biomarker_diagnosis_ns hsa-mir-1165 Allergic Asthma 30015513 A novel microRNA miR-1165-3p as a potential diagnostic biomarker for allergic asthma. circulation_biomarker_diagnosis_ns hsa-mir-21 Hepatic Veno-Occlusive Disease 30019166 we found that LSEC-derived miR-21-5p and especially miR-511-3p in serum would serve as early phase biomarkers for SOS in response to LSEC damage circulation_biomarker_diagnosis_ns hsa-mir-511 Hepatic Veno-Occlusive Disease 30019166 we found that LSEC-derived miR-21-5p and especially miR-511-3p in serum would serve as early phase biomarkers for SOS in response to LSEC damage circulation_biomarker_diagnosis_ns hsa-mir-155 Lymphoma 30021904 Enhancer control of miR-155 expression in Epstein-Barr virus infected B cells. circulation_biomarker_diagnosis_ns hsa-mir-122 "Fatty Liver, Non-Alcoholic" 30030064 "Plasma miR-17, miR-20a, miR-20b and miR-122 as potential biomarkers for diagnosis of NAFLD in type 2 diabetes mellitus patients." circulation_biomarker_diagnosis_ns hsa-mir-17 "Fatty Liver, Non-Alcoholic" 30030064 "Plasma miR-17, miR-20a, miR-20b and miR-122 as potential biomarkers for diagnosis of NAFLD in type 2 diabetes mellitus patients." circulation_biomarker_diagnosis_ns hsa-mir-20a "Fatty Liver, Non-Alcoholic" 30030064 "Plasma miR-17, miR-20a, miR-20b and miR-122 as potential biomarkers for diagnosis of NAFLD in type 2 diabetes mellitus patients." circulation_biomarker_diagnosis_ns hsa-mir-20b "Fatty Liver, Non-Alcoholic" 30030064 "Plasma miR-17, miR-20a, miR-20b and miR-122 as potential biomarkers for diagnosis of NAFLD in type 2 diabetes mellitus patients." circulation_biomarker_diagnosis_ns hsa-mir-126 Acute Ischemic Stroke 30030634 "Circulating miR-126 and miR-130a levels correlate with lower disease risk, disease severity, and reduced inflammatory cytokine levels in acute ischemic stroke patients." circulation_biomarker_diagnosis_ns hsa-mir-130a Acute Ischemic Stroke 30030634 "Circulating miR-126 and miR-130a levels correlate with lower disease risk, disease severity, and reduced inflammatory cytokine levels in acute ischemic stroke patients." circulation_biomarker_diagnosis_ns hsa-let-7c Graft-Versus-Host Disease 30042760 Differential MicroRNA Expression Levels in Cutaneous Acute Graft-Versus-Host Disease. circulation_biomarker_diagnosis_ns hsa-mir-34a Graft-Versus-Host Disease 30042760 Differential MicroRNA Expression Levels in Cutaneous Acute Graft-Versus-Host Disease. circulation_biomarker_diagnosis_ns hsa-mir-365a Graft-Versus-Host Disease 30042760 Differential MicroRNA Expression Levels in Cutaneous Acute Graft-Versus-Host Disease. circulation_biomarker_diagnosis_ns hsa-mir-503 Graft-Versus-Host Disease 30042760 Differential MicroRNA Expression Levels in Cutaneous Acute Graft-Versus-Host Disease. circulation_biomarker_diagnosis_ns hsa-mir-1915 "Carcinoma, Breast" 30048472 Identification of serum miR-1915-3p and miR-455-3p as biomarkers for breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-455 "Carcinoma, Breast" 30048472 Identification of serum miR-1915-3p and miR-455-3p as biomarkers for breast cancer. circulation_biomarker_diagnosis_ns hsa-mir-142 Cerebral Malaria 30050092 "Differentially expressed microRNAs in experimental cerebral malaria and their involvement in endocytosis, adherens junctions, FoxO and TGF-¦Â signalling pathways." circulation_biomarker_diagnosis_ns hsa-mir-19a Cerebral Malaria 30050092 "Differentially expressed microRNAs in experimental cerebral malaria and their involvement in endocytosis, adherens junctions, FoxO and TGF-¦Â signalling pathways." circulation_biomarker_diagnosis_ns hsa-mir-19b Cerebral Malaria 30050092 "Differentially expressed microRNAs in experimental cerebral malaria and their involvement in endocytosis, adherens junctions, FoxO and TGF-¦Â signalling pathways." circulation_biomarker_diagnosis_ns hsa-mir-223 Cerebral Malaria 30050092 "Differentially expressed microRNAs in experimental cerebral malaria and their involvement in endocytosis, adherens junctions, FoxO and TGF-¦Â signalling pathways." circulation_biomarker_diagnosis_ns hsa-mir-126 Heart Failure 30054123 Serum microRNA-126 and -223 as new-generation biomarkers for sarcoidosis in patients with heart failure. circulation_biomarker_diagnosis_ns hsa-mir-223 Heart Failure 30054123 Serum microRNA-126 and -223 as new-generation biomarkers for sarcoidosis in patients with heart failure. circulation_biomarker_diagnosis_ns hsa-mir-488 "Carcinoma, Breast" 30061217 Circulating Pre-microRNA-488 in Peripheral Blood Is a Potential Biomarker for Predicting Recurrence in Breast Cancer. circulation_biomarker_diagnosis_ns hsa-mir-144 "Carcinoma, Hepatocellular" 30065664 Extracellular Vesicle-Associated mir-21 and mir-144 Are Markedly Elevated in Serum of Patients With Hepatocellular Carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-21 "Carcinoma, Hepatocellular" 30065664 Extracellular Vesicle-Associated mir-21 and mir-144 Are Markedly Elevated in Serum of Patients With Hepatocellular Carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-106a Inflammatory Bowel Diseases 30069249 Micro-RNAs -106a and -362-3p in Peripheral Blood of Inflammatory Bowel Disease Patients. circulation_biomarker_diagnosis_ns hsa-mir-362 Inflammatory Bowel Diseases 30069249 Micro-RNAs -106a and -362-3p in Peripheral Blood of Inflammatory Bowel Disease Patients. circulation_biomarker_diagnosis_ns hsa-mir-183 Asthma 30074411 "Circulating miRs-183-5p, -206-3p and -381-3p may serve as novel biomarkers for 4,4'-methylene diphenyl diisocyanate exposure." circulation_biomarker_diagnosis_ns hsa-mir-206 Asthma 30074411 "Circulating miRs-183-5p, -206-3p and -381-3p may serve as novel biomarkers for 4,4'-methylene diphenyl diisocyanate exposure." circulation_biomarker_diagnosis_ns hsa-mir-381 Asthma 30074411 "Circulating miRs-183-5p, -206-3p and -381-3p may serve as novel biomarkers for 4,4'-methylene diphenyl diisocyanate exposure." circulation_biomarker_diagnosis_ns hsa-mir-155 "Lymphoma, Large B-Cell, Diffuse" 30076183 "MicroRNA profiling of diffuse large B-cell lymphoma cells treated with OTX015 revealed changes in the expression levels of a limited number of microRNAs, including miR-92a-1-5p, miR-21-3p, miR-155-5p and miR-96-5p" circulation_biomarker_diagnosis_ns hsa-mir-21 "Lymphoma, Large B-Cell, Diffuse" 30076183 "MicroRNA profiling of diffuse large B-cell lymphoma cells treated with OTX015 revealed changes in the expression levels of a limited number of microRNAs, including miR-92a-1-5p, miR-21-3p, miR-155-5p and miR-96-5p" circulation_biomarker_diagnosis_ns hsa-mir-92a "Lymphoma, Large B-Cell, Diffuse" 30076183 "MicroRNA profiling of diffuse large B-cell lymphoma cells treated with OTX015 revealed changes in the expression levels of a limited number of microRNAs, including miR-92a-1-5p, miR-21-3p, miR-155-5p and miR-96-5p" circulation_biomarker_diagnosis_ns hsa-mir-96 "Lymphoma, Large B-Cell, Diffuse" 30076183 "MicroRNA profiling of diffuse large B-cell lymphoma cells treated with OTX015 revealed changes in the expression levels of a limited number of microRNAs, including miR-92a-1-5p, miR-21-3p, miR-155-5p and miR-96-5p" circulation_biomarker_diagnosis_ns hsa-mir-193b "Diabetes Mellitus, Type 2" 30083267 "Levels of miR-193b-3p, miR-199a-3p, miR-20a-3p, miR-26b-5p, miR-30b-5p, miR-30c-5p, miR-374a-5p, miR-409-3p, and miR-95-3p were significantly different between Ects obtained from patients with T2DM and those obtained from healthy controls" circulation_biomarker_diagnosis_ns hsa-mir-199a "Diabetes Mellitus, Type 2" 30083267 "Levels of miR-193b-3p, miR-199a-3p, miR-20a-3p, miR-26b-5p, miR-30b-5p, miR-30c-5p, miR-374a-5p, miR-409-3p, and miR-95-3p were significantly different between Ects obtained from patients with T2DM and those obtained from healthy controls" circulation_biomarker_diagnosis_ns hsa-mir-20a "Diabetes Mellitus, Type 2" 30083267 "Levels of miR-193b-3p, miR-199a-3p, miR-20a-3p, miR-26b-5p, miR-30b-5p, miR-30c-5p, miR-374a-5p, miR-409-3p, and miR-95-3p were significantly different between Ects obtained from patients with T2DM and those obtained from healthy controls" circulation_biomarker_diagnosis_ns hsa-mir-26b "Diabetes Mellitus, Type 2" 30083267 "Levels of miR-193b-3p, miR-199a-3p, miR-20a-3p, miR-26b-5p, miR-30b-5p, miR-30c-5p, miR-374a-5p, miR-409-3p, and miR-95-3p were significantly different between Ects obtained from patients with T2DM and those obtained from healthy controls" circulation_biomarker_diagnosis_ns hsa-mir-30b "Diabetes Mellitus, Type 2" 30083267 "Levels of miR-193b-3p, miR-199a-3p, miR-20a-3p, miR-26b-5p, miR-30b-5p, miR-30c-5p, miR-374a-5p, miR-409-3p, and miR-95-3p were significantly different between Ects obtained from patients with T2DM and those obtained from healthy controls" circulation_biomarker_diagnosis_ns hsa-mir-30c "Diabetes Mellitus, Type 2" 30083267 "Levels of miR-193b-3p, miR-199a-3p, miR-20a-3p, miR-26b-5p, miR-30b-5p, miR-30c-5p, miR-374a-5p, miR-409-3p, and miR-95-3p were significantly different between Ects obtained from patients with T2DM and those obtained from healthy controls" circulation_biomarker_diagnosis_ns hsa-mir-374a "Diabetes Mellitus, Type 2" 30083267 "Levels of miR-193b-3p, miR-199a-3p, miR-20a-3p, miR-26b-5p, miR-30b-5p, miR-30c-5p, miR-374a-5p, miR-409-3p, and miR-95-3p were significantly different between Ects obtained from patients with T2DM and those obtained from healthy controls" circulation_biomarker_diagnosis_ns hsa-mir-409 "Diabetes Mellitus, Type 2" 30083267 "Levels of miR-193b-3p, miR-199a-3p, miR-20a-3p, miR-26b-5p, miR-30b-5p, miR-30c-5p, miR-374a-5p, miR-409-3p, and miR-95-3p were significantly different between Ects obtained from patients with T2DM and those obtained from healthy controls" circulation_biomarker_diagnosis_ns hsa-mir-95 "Diabetes Mellitus, Type 2" 30083267 "Levels of miR-193b-3p, miR-199a-3p, miR-20a-3p, miR-26b-5p, miR-30b-5p, miR-30c-5p, miR-374a-5p, miR-409-3p, and miR-95-3p were significantly different between Ects obtained from patients with T2DM and those obtained from healthy controls" circulation_biomarker_diagnosis_ns hsa-mir-134 Gastric Neoplasms 30083331 "We further validated the deregulation of miR-196a-5p in precursor lesions of gastric cancer and the deregulation of miR-134-5p, miR-144-3p and miR-451a in gastric cancer" circulation_biomarker_diagnosis_ns hsa-mir-144 Gastric Neoplasms 30083331 "We further validated the deregulation of miR-196a-5p in precursor lesions of gastric cancer and the deregulation of miR-134-5p, miR-144-3p and miR-451a in gastric cancer" circulation_biomarker_diagnosis_ns hsa-mir-196a Gastric Neoplasms 30083331 "We further validated the deregulation of miR-196a-5p in precursor lesions of gastric cancer and the deregulation of miR-134-5p, miR-144-3p and miR-451a in gastric cancer" circulation_biomarker_diagnosis_ns hsa-mir-451a Gastric Neoplasms 30083331 "We further validated the deregulation of miR-196a-5p in precursor lesions of gastric cancer and the deregulation of miR-134-5p, miR-144-3p and miR-451a in gastric cancer" circulation_biomarker_diagnosis_ns hsa-mir-19b Coronary Artery Disease 30088484 "Combination of peripheral blood mononuclear cell miR-19b-5p, miR- 221, miR-25-5p, and hypertension correlates with an increased heart failure risk in coronary heart disease patients." circulation_biomarker_diagnosis_ns hsa-mir-221 Coronary Artery Disease 30088484 "Combination of peripheral blood mononuclear cell miR-19b-5p, miR- 221, miR-25-5p, and hypertension correlates with an increased heart failure risk in coronary heart disease patients." circulation_biomarker_diagnosis_ns hsa-mir-25 Coronary Artery Disease 30088484 "Combination of peripheral blood mononuclear cell miR-19b-5p, miR- 221, miR-25-5p, and hypertension correlates with an increased heart failure risk in coronary heart disease patients." circulation_biomarker_diagnosis_ns hsa-mir-22 Pulmonary Hypertension 30090067 Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention. circulation_biomarker_diagnosis_ns hsa-mir-451a Pulmonary Hypertension 30090067 Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention. circulation_biomarker_diagnosis_ns hsa-mir-126 "Diabetes Mellitus, Type 2" 30093963 "For instance, three miRNAs (miR-126-3p, miR-28-3p miR-486-5p) were dysregulated in prediabetes compared to screen-detected diabetes" circulation_biomarker_diagnosis_ns hsa-mir-28 "Diabetes Mellitus, Type 2" 30093963 "For instance, three miRNAs (miR-126-3p, miR-28-3p miR-486-5p) were dysregulated in prediabetes compared to screen-detected diabetes" circulation_biomarker_diagnosis_ns hsa-mir-486 "Diabetes Mellitus, Type 2" 30093963 "For instance, three miRNAs (miR-126-3p, miR-28-3p miR-486-5p) were dysregulated in prediabetes compared to screen-detected diabetes" circulation_biomarker_diagnosis_ns hsa-mir-30a "Squamous Cell Carcinoma, Oral" 30098778 The proposed combination of miR-30a-5p and miR-769-5p in plasma from OSCC patients could serve as a minimal invasive biomarker for diagnosis and control of T-site recurrences circulation_biomarker_diagnosis_ns hsa-mir-769 "Squamous Cell Carcinoma, Oral" 30098778 The proposed combination of miR-30a-5p and miR-769-5p in plasma from OSCC patients could serve as a minimal invasive biomarker for diagnosis and control of T-site recurrences circulation_biomarker_diagnosis_ns hsa-mir-21 Systemic Lupus Erythematosus 30105262 "miR-22-3p¦¤CT and miR-21-5p¦¤CT, were negatively correlated with caspase-10 levels, which may repress extrinsic apoptosis and increase cell survival" circulation_biomarker_diagnosis_ns hsa-mir-22 Systemic Lupus Erythematosus 30105262 "miR-22-3p¦¤CT and miR-21-5p¦¤CT, were negatively correlated with caspase-10 levels, which may repress extrinsic apoptosis and increase cell survival" circulation_biomarker_diagnosis_ns hsa-mir-146a Hypertension 30107841 Urinary exosome miR-146a is a potential marker of albuminuria in essential hypertension. circulation_biomarker_diagnosis_ns hsa-mir-221 Cardiovascular Diseases [unspecific] 30115076 The inverted pattern of circulating miR-221-3p and miR-222-3p associated with isolated low HDL-C phenotype. circulation_biomarker_diagnosis_ns hsa-mir-222 Cardiovascular Diseases [unspecific] 30115076 The inverted pattern of circulating miR-221-3p and miR-222-3p associated with isolated low HDL-C phenotype. circulation_biomarker_diagnosis_ns hsa-mir-21 Frailty 30116492 Positive correlations between miR-21 and AOPP and between miR-483 and IL-8 were detected circulation_biomarker_diagnosis_ns hsa-mir-483 Frailty 30116492 Positive correlations between miR-21 and AOPP and between miR-483 and IL-8 were detected circulation_biomarker_diagnosis_ns hsa-mir-103a Spinal Cord Injuries 30122113 "miR-125b-5p, miR-146a-5p, miR-328-3p, miR-191-5p, miR-103a-3p, and miR-30b-5p correlated with both oxLDL and cIMT, and showed distinct expression between the SCI-A and SCI-S groups" circulation_biomarker_diagnosis_ns hsa-mir-125b Spinal Cord Injuries 30122113 "miR-125b-5p, miR-146a-5p, miR-328-3p, miR-191-5p, miR-103a-3p, and miR-30b-5p correlated with both oxLDL and cIMT, and showed distinct expression between the SCI-A and SCI-S groups" circulation_biomarker_diagnosis_ns hsa-mir-146a Spinal Cord Injuries 30122113 "miR-125b-5p, miR-146a-5p, miR-328-3p, miR-191-5p, miR-103a-3p, and miR-30b-5p correlated with both oxLDL and cIMT, and showed distinct expression between the SCI-A and SCI-S groups" circulation_biomarker_diagnosis_ns hsa-mir-191 Spinal Cord Injuries 30122113 "miR-125b-5p, miR-146a-5p, miR-328-3p, miR-191-5p, miR-103a-3p, and miR-30b-5p correlated with both oxLDL and cIMT, and showed distinct expression between the SCI-A and SCI-S groups" circulation_biomarker_diagnosis_ns hsa-mir-30b Spinal Cord Injuries 30122113 "miR-125b-5p, miR-146a-5p, miR-328-3p, miR-191-5p, miR-103a-3p, and miR-30b-5p correlated with both oxLDL and cIMT, and showed distinct expression between the SCI-A and SCI-S groups" circulation_biomarker_diagnosis_ns hsa-mir-328 Spinal Cord Injuries 30122113 "miR-125b-5p, miR-146a-5p, miR-328-3p, miR-191-5p, miR-103a-3p, and miR-30b-5p correlated with both oxLDL and cIMT, and showed distinct expression between the SCI-A and SCI-S groups" circulation_biomarker_diagnosis_ns hsa-let-7b Liver Injury 30125006 "Identification of Specific MicroRNA Biomarkers in Early Stages of Hepatocellular Injury, Cholestasis, and Steatosis in Rats." circulation_biomarker_diagnosis_ns hsa-mir-1 Liver Injury 30125006 "Identification of Specific MicroRNA Biomarkers in Early Stages of Hepatocellular Injury, Cholestasis, and Steatosis in Rats." circulation_biomarker_diagnosis_ns hsa-mir-143 Liver Injury 30125006 "Identification of Specific MicroRNA Biomarkers in Early Stages of Hepatocellular Injury, Cholestasis, and Steatosis in Rats." circulation_biomarker_diagnosis_ns hsa-mir-218a Liver Injury 30125006 "Identification of Specific MicroRNA Biomarkers in Early Stages of Hepatocellular Injury, Cholestasis, and Steatosis in Rats." circulation_biomarker_diagnosis_ns hsa-mir-320 Liver Injury 30125006 "Identification of Specific MicroRNA Biomarkers in Early Stages of Hepatocellular Injury, Cholestasis, and Steatosis in Rats." circulation_biomarker_diagnosis_ns hsa-mir-208a Coronary Artery Disease 30126654 "Droplet digital PCR of serum miR-499, miR-21 and miR-208a for the detection of functionally relevant coronary artery disease." circulation_biomarker_diagnosis_ns hsa-mir-21 Coronary Artery Disease 30126654 "Droplet digital PCR of serum miR-499, miR-21 and miR-208a for the detection of functionally relevant coronary artery disease." circulation_biomarker_diagnosis_ns hsa-mir-499 Coronary Artery Disease 30126654 "Droplet digital PCR of serum miR-499, miR-21 and miR-208a for the detection of functionally relevant coronary artery disease." circulation_biomarker_diagnosis_ns hsa-mir-30d Multiple Myeloma 30132507 Serum miR-30d as a novel biomarker for multiple myeloma and its antitumor role in U266 cells through the targeting of the MTDH/PI3K/Akt signaling pathway. circulation_biomarker_diagnosis_ns hsa-mir-1260a Melanoma 30132912 Differential expression of miR-150-5p and miR-1260a is present in plasma following surgical resection of metastatic melanoma in this small sample (n?=?6) of melanoma patients circulation_biomarker_diagnosis_ns hsa-mir-150 Melanoma 30132912 Differential expression of miR-150-5p and miR-1260a is present in plasma following surgical resection of metastatic melanoma in this small sample (n?=?6) of melanoma patients circulation_biomarker_diagnosis_ns hsa-mir-106 Hepatitis C Virus Infection 30133717 "miR-23b and miR-106 might be a useful biomarker for chronic hepatitis C (CHC). MiR-27a, miR-93, and miR-199 might have a potential role in the progression of liver diseases" circulation_biomarker_diagnosis_ns hsa-mir-23b Hepatitis C Virus Infection 30133717 "miR-23b and miR-106 might be a useful biomarker for chronic hepatitis C (CHC). MiR-27a, miR-93, and miR-199 might have a potential role in the progression of liver diseases" circulation_biomarker_diagnosis_ns hsa-let-7b "Leukemia, Lymphoblastic, Acute" 30139235 Expression of Micro-RNA 128 and Let-7b in Pediatric Acute Lymphoblastic Leukemia Cases circulation_biomarker_diagnosis_ns hsa-mir-128 "Leukemia, Lymphoblastic, Acute" 30139235 Expression of Micro-RNA 128 and Let-7b in Pediatric Acute Lymphoblastic Leukemia Cases circulation_biomarker_diagnosis_ns hsa-mir-125b Graft-Versus-Host Disease 30142940 "we selected the 10 miRNAs (miR-423-5p, miR-19a, miR-142-3p, miR-128, miR-193b, miR-30c, miR-193a, miR-191, miR-125b, and miR-574-3p) with the most significant differential expression" circulation_biomarker_diagnosis_ns hsa-mir-128 Graft-Versus-Host Disease 30142940 "we selected the 10 miRNAs (miR-423-5p, miR-19a, miR-142-3p, miR-128, miR-193b, miR-30c, miR-193a, miR-191, miR-125b, and miR-574-3p) with the most significant differential expression" circulation_biomarker_diagnosis_ns hsa-mir-142 Graft-Versus-Host Disease 30142940 "we selected the 10 miRNAs (miR-423-5p, miR-19a, miR-142-3p, miR-128, miR-193b, miR-30c, miR-193a, miR-191, miR-125b, and miR-574-3p) with the most significant differential expression" circulation_biomarker_diagnosis_ns hsa-mir-191 Graft-Versus-Host Disease 30142940 "we selected the 10 miRNAs (miR-423-5p, miR-19a, miR-142-3p, miR-128, miR-193b, miR-30c, miR-193a, miR-191, miR-125b, and miR-574-3p) with the most significant differential expression" circulation_biomarker_diagnosis_ns hsa-mir-193a Graft-Versus-Host Disease 30142940 "we selected the 10 miRNAs (miR-423-5p, miR-19a, miR-142-3p, miR-128, miR-193b, miR-30c, miR-193a, miR-191, miR-125b, and miR-574-3p) with the most significant differential expression" circulation_biomarker_diagnosis_ns hsa-mir-193b Graft-Versus-Host Disease 30142940 "we selected the 10 miRNAs (miR-423-5p, miR-19a, miR-142-3p, miR-128, miR-193b, miR-30c, miR-193a, miR-191, miR-125b, and miR-574-3p) with the most significant differential expression" circulation_biomarker_diagnosis_ns hsa-mir-19a Graft-Versus-Host Disease 30142940 "we selected the 10 miRNAs (miR-423-5p, miR-19a, miR-142-3p, miR-128, miR-193b, miR-30c, miR-193a, miR-191, miR-125b, and miR-574-3p) with the most significant differential expression" circulation_biomarker_diagnosis_ns hsa-mir-30c Graft-Versus-Host Disease 30142940 "we selected the 10 miRNAs (miR-423-5p, miR-19a, miR-142-3p, miR-128, miR-193b, miR-30c, miR-193a, miR-191, miR-125b, and miR-574-3p) with the most significant differential expression" circulation_biomarker_diagnosis_ns hsa-mir-423 Graft-Versus-Host Disease 30142940 "we selected the 10 miRNAs (miR-423-5p, miR-19a, miR-142-3p, miR-128, miR-193b, miR-30c, miR-193a, miR-191, miR-125b, and miR-574-3p) with the most significant differential expression" circulation_biomarker_diagnosis_ns hsa-mir-574 Graft-Versus-Host Disease 30142940 "we selected the 10 miRNAs (miR-423-5p, miR-19a, miR-142-3p, miR-128, miR-193b, miR-30c, miR-193a, miR-191, miR-125b, and miR-574-3p) with the most significant differential expression" circulation_biomarker_diagnosis_ns hsa-mir-144 Coronary Artery Disease 30143484 Altered Plasma miR-144 as a Novel Biomarker for Coronary Artery Disease. circulation_biomarker_diagnosis_ns hsa-mir-12 Viral Infectious Disease 30146762 "To date, numerous biomarkers have been identified for thediagnostic or prognostic purpose; for instance, miR-182, miR-486, and miR15a in sepsis; miR-320 and miR505 in inflammatory bowel disease; miR-155 and miR-1260 in influenza; miR-12, miRVP-3p, and miR-184 in arboviruses; and miR-29b and miR-125 in hepatitis infection" circulation_biomarker_diagnosis_ns hsa-mir-125 Hepatitis [unspecific] 30146762 "To date, numerous biomarkers have been identified for thediagnostic or prognostic purpose; for instance, miR-182, miR-486, and miR15a in sepsis; miR-320 and miR505 in inflammatory bowel disease; miR-155 and miR-1260 in influenza; miR-12, miRVP-3p, and miR-184 in arboviruses; and miR-29b and miR-125 in hepatitis infection" circulation_biomarker_diagnosis_ns hsa-mir-1260 Influenza 30146762 "To date, numerous biomarkers have been identified for thediagnostic or prognostic purpose; for instance, miR-182, miR-486, and miR15a in sepsis; miR-320 and miR505 in inflammatory bowel disease; miR-155 and miR-1260 in influenza; miR-12, miRVP-3p, and miR-184 in arboviruses; and miR-29b and miR-125 in hepatitis infection" circulation_biomarker_diagnosis_ns hsa-mir-155 Influenza 30146762 "To date, numerous biomarkers have been identified for thediagnostic or prognostic purpose; for instance, miR-182, miR-486, and miR15a in sepsis; miR-320 and miR505 in inflammatory bowel disease; miR-155 and miR-1260 in influenza; miR-12, miRVP-3p, and miR-184 in arboviruses; and miR-29b and miR-125 in hepatitis infection" circulation_biomarker_diagnosis_ns hsa-mir-15a Sepsis 30146762 "To date, numerous biomarkers have been identified for thediagnostic or prognostic purpose; for instance, miR-182, miR-486, and miR15a in sepsis; miR-320 and miR505 in inflammatory bowel disease; miR-155 and miR-1260 in influenza; miR-12, miRVP-3p, and miR-184 in arboviruses; and miR-29b and miR-125 in hepatitis infection" circulation_biomarker_diagnosis_ns hsa-mir-182 Sepsis 30146762 "To date, numerous biomarkers have been identified for thediagnostic or prognostic purpose; for instance, miR-182, miR-486, and miR15a in sepsis; miR-320 and miR505 in inflammatory bowel disease; miR-155 and miR-1260 in influenza; miR-12, miRVP-3p, and miR-184 in arboviruses; and miR-29b and miR-125 in hepatitis infection" circulation_biomarker_diagnosis_ns hsa-mir-184 Viral Infectious Disease 30146762 "To date, numerous biomarkers have been identified for thediagnostic or prognostic purpose; for instance, miR-182, miR-486, and miR15a in sepsis; miR-320 and miR505 in inflammatory bowel disease; miR-155 and miR-1260 in influenza; miR-12, miRVP-3p, and miR-184 in arboviruses; and miR-29b and miR-125 in hepatitis infection" circulation_biomarker_diagnosis_ns hsa-mir-29b Hepatitis [unspecific] 30146762 "To date, numerous biomarkers have been identified for thediagnostic or prognostic purpose; for instance, miR-182, miR-486, and miR15a in sepsis; miR-320 and miR505 in inflammatory bowel disease; miR-155 and miR-1260 in influenza; miR-12, miRVP-3p, and miR-184 in arboviruses; and miR-29b and miR-125 in hepatitis infection" circulation_biomarker_diagnosis_ns hsa-mir-320 Inflammatory Bowel Diseases 30146762 "To date, numerous biomarkers have been identified for thediagnostic or prognostic purpose; for instance, miR-182, miR-486, and miR15a in sepsis; miR-320 and miR505 in inflammatory bowel disease; miR-155 and miR-1260 in influenza; miR-12, miRVP-3p, and miR-184 in arboviruses; and miR-29b and miR-125 in hepatitis infection" circulation_biomarker_diagnosis_ns hsa-mir-486 Sepsis 30146762 "To date, numerous biomarkers have been identified for thediagnostic or prognostic purpose; for instance, miR-182, miR-486, and miR15a in sepsis; miR-320 and miR505 in inflammatory bowel disease; miR-155 and miR-1260 in influenza; miR-12, miRVP-3p, and miR-184 in arboviruses; and miR-29b and miR-125 in hepatitis infection" circulation_biomarker_diagnosis_ns hsa-mir-505 Inflammatory Bowel Diseases 30146762 "To date, numerous biomarkers have been identified for thediagnostic or prognostic purpose; for instance, miR-182, miR-486, and miR15a in sepsis; miR-320 and miR505 in inflammatory bowel disease; miR-155 and miR-1260 in influenza; miR-12, miRVP-3p, and miR-184 in arboviruses; and miR-29b and miR-125 in hepatitis infection" circulation_biomarker_diagnosis_ns hsa-mir-140 Osteoporosis 30171938 Serum miRNAs miR-140-3p and miR-23b-3p as potential biomarkers for osteoporosis and osteoporotic fracture in postmenopausal Mexican-Mestizo women. circulation_biomarker_diagnosis_ns hsa-mir-23b Osteoporosis 30171938 Serum miRNAs miR-140-3p and miR-23b-3p as potential biomarkers for osteoporosis and osteoporotic fracture in postmenopausal Mexican-Mestizo women. circulation_biomarker_diagnosis_ns hsa-let-7b Atherosclerosis 30178428 "miR-125b, miR-125a, let-7b, and let-7e could discriminate CARD patients from normal controls and other subtypes. Furthermore, ROC curves shown that miR-7-2-3p and miR-1908 showed significant area-under-the-curve values in both LAA and LAC patients" circulation_biomarker_diagnosis_ns hsa-let-7e Atherosclerosis 30178428 "miR-125b, miR-125a, let-7b, and let-7e could discriminate CARD patients from normal controls and other subtypes. Furthermore, ROC curves shown that miR-7-2-3p and miR-1908 showed significant area-under-the-curve values in both LAA and LAC patients" circulation_biomarker_diagnosis_ns hsa-mir-125a Atherosclerosis 30178428 "miR-125b, miR-125a, let-7b, and let-7e could discriminate CARD patients from normal controls and other subtypes. Furthermore, ROC curves shown that miR-7-2-3p and miR-1908 showed significant area-under-the-curve values in both LAA and LAC patients" circulation_biomarker_diagnosis_ns hsa-mir-125b Atherosclerosis 30178428 "miR-125b, miR-125a, let-7b, and let-7e could discriminate CARD patients from normal controls and other subtypes. Furthermore, ROC curves shown that miR-7-2-3p and miR-1908 showed significant area-under-the-curve values in both LAA and LAC patients" circulation_biomarker_diagnosis_ns hsa-mir-1908 Atherosclerosis 30178428 "miR-125b, miR-125a, let-7b, and let-7e could discriminate CARD patients from normal controls and other subtypes. Furthermore, ROC curves shown that miR-7-2-3p and miR-1908 showed significant area-under-the-curve values in both LAA and LAC patients" circulation_biomarker_diagnosis_ns hsa-mir-7-2 Atherosclerosis 30178428 "miR-125b, miR-125a, let-7b, and let-7e could discriminate CARD patients from normal controls and other subtypes. Furthermore, ROC curves shown that miR-7-2-3p and miR-1908 showed significant area-under-the-curve values in both LAA and LAC patients" circulation_biomarker_diagnosis_ns hsa-mir-376 Preeclampsia 30186390 Expression of miR-376 in blood of pregnant women with preeclampsia and its effect on 25-hydroxyvitamin D. circulation_biomarker_diagnosis_ns hsa-mir-134 Kawasaki Syndrome 30186482 "Serum exosomal miR-328, miR-575, miR-134 and miR-671-5p as potential biomarkers for the diagnosis of Kawasaki disease and the prediction of therapeutic outcomes of intravenous immunoglobulin therapy." circulation_biomarker_diagnosis_ns hsa-mir-328 Kawasaki Syndrome 30186482 "Serum exosomal miR-328, miR-575, miR-134 and miR-671-5p as potential biomarkers for the diagnosis of Kawasaki disease and the prediction of therapeutic outcomes of intravenous immunoglobulin therapy." circulation_biomarker_diagnosis_ns hsa-mir-575 Kawasaki Syndrome 30186482 "Serum exosomal miR-328, miR-575, miR-134 and miR-671-5p as potential biomarkers for the diagnosis of Kawasaki disease and the prediction of therapeutic outcomes of intravenous immunoglobulin therapy." circulation_biomarker_diagnosis_ns hsa-mir-671 Kawasaki Syndrome 30186482 "Serum exosomal miR-328, miR-575, miR-134 and miR-671-5p as potential biomarkers for the diagnosis of Kawasaki disease and the prediction of therapeutic outcomes of intravenous immunoglobulin therapy." circulation_biomarker_diagnosis_ns hsa-mir-103a "Carcinoma, Breast" 30220214 miR-24 and miR-103a were valuable biomarkers for distinguishing AH and early-stage BC from healthy individuals/benign proliferative tumor patients circulation_biomarker_diagnosis_ns hsa-mir-24 "Carcinoma, Breast" 30220214 miR-24 and miR-103a were valuable biomarkers for distinguishing AH and early-stage BC from healthy individuals/benign proliferative tumor patients circulation_biomarker_diagnosis_ns hsa-mir-331 "Adenocarcinoma, Esophageal" 30228315 Serum miR-331-3p predicts tumor recurrence in esophageal adenocarcinoma. circulation_biomarker_diagnosis_ns hsa-mir-126 Glioma 30233327 "Many microRNAs (miRNAs) such as miR-183, miR-9, miR-137 and miR-126 expression change may be involved in the cross talk between glioma prevalence and schizophrenia" circulation_biomarker_diagnosis_ns hsa-mir-126 Schizophrenia 30233327 "Many microRNAs (miRNAs) such as miR-183, miR-9, miR-137 and miR-126 expression change may be involved in the cross talk between glioma prevalence and schizophrenia" circulation_biomarker_diagnosis_ns hsa-mir-137 Glioma 30233327 "Many microRNAs (miRNAs) such as miR-183, miR-9, miR-137 and miR-126 expression change may be involved in the cross talk between glioma prevalence and schizophrenia" circulation_biomarker_diagnosis_ns hsa-mir-137 Schizophrenia 30233327 "Many microRNAs (miRNAs) such as miR-183, miR-9, miR-137 and miR-126 expression change may be involved in the cross talk between glioma prevalence and schizophrenia" circulation_biomarker_diagnosis_ns hsa-mir-183 Glioma 30233327 "Many microRNAs (miRNAs) such as miR-183, miR-9, miR-137 and miR-126 expression change may be involved in the cross talk between glioma prevalence and schizophrenia" circulation_biomarker_diagnosis_ns hsa-mir-183 Schizophrenia 30233327 "Many microRNAs (miRNAs) such as miR-183, miR-9, miR-137 and miR-126 expression change may be involved in the cross talk between glioma prevalence and schizophrenia" circulation_biomarker_diagnosis_ns hsa-mir-9 Glioma 30233327 "Many microRNAs (miRNAs) such as miR-183, miR-9, miR-137 and miR-126 expression change may be involved in the cross talk between glioma prevalence and schizophrenia" circulation_biomarker_diagnosis_ns hsa-mir-9 Schizophrenia 30233327 "Many microRNAs (miRNAs) such as miR-183, miR-9, miR-137 and miR-126 expression change may be involved in the cross talk between glioma prevalence and schizophrenia" circulation_biomarker_diagnosis_ns hsa-mir-138 Lung Neoplasms 30233883 "We validated a panel of miRNAs (hsa-miR-199a-3p, hsa-miR-148a-3p, hsa-miR-210-3p, hsa-miR-378d and hsa-miR-138-5p) to aid early diagnosis of lung adenocarcinoma by blood test in lung cancer" circulation_biomarker_diagnosis_ns hsa-mir-148a Lung Neoplasms 30233883 "We validated a panel of miRNAs (hsa-miR-199a-3p, hsa-miR-148a-3p, hsa-miR-210-3p, hsa-miR-378d and hsa-miR-138-5p) to aid early diagnosis of lung adenocarcinoma by blood test in lung cancer" circulation_biomarker_diagnosis_ns hsa-mir-199a Lung Neoplasms 30233883 "We validated a panel of miRNAs (hsa-miR-199a-3p, hsa-miR-148a-3p, hsa-miR-210-3p, hsa-miR-378d and hsa-miR-138-5p) to aid early diagnosis of lung adenocarcinoma by blood test in lung cancer" circulation_biomarker_diagnosis_ns hsa-mir-210 Lung Neoplasms 30233883 "We validated a panel of miRNAs (hsa-miR-199a-3p, hsa-miR-148a-3p, hsa-miR-210-3p, hsa-miR-378d and hsa-miR-138-5p) to aid early diagnosis of lung adenocarcinoma by blood test in lung cancer" circulation_biomarker_diagnosis_ns hsa-mir-378d Lung Neoplasms 30233883 "We validated a panel of miRNAs (hsa-miR-199a-3p, hsa-miR-148a-3p, hsa-miR-210-3p, hsa-miR-378d and hsa-miR-138-5p) to aid early diagnosis of lung adenocarcinoma by blood test in lung cancer" circulation_biomarker_diagnosis_ns hsa-mir-192 Diabetes Mellitus 30250222 Circulating microRNAs -192 and -194 are associated with the presence and incidence of diabetes mellitus. circulation_biomarker_diagnosis_ns hsa-mir-194 Diabetes Mellitus 30250222 Circulating microRNAs -192 and -194 are associated with the presence and incidence of diabetes mellitus. circulation_biomarker_diagnosis_ns hsa-mir-223 Prostate Neoplasms 30250541 Monitoring of platelet function parameters and microRNA expression levels in patients with prostate cancer treated with volumetric modulated arc radiotherapy. circulation_biomarker_diagnosis_ns hsa-mir-122 "Fatty Liver, Non-Alcoholic" 30252499 "The liver-specific microRNAs including miR-122, miR-130,miR-183, miR-196, miR-209 and miR-96 are potential indicators of liver injury" circulation_biomarker_diagnosis_ns hsa-mir-130 "Fatty Liver, Non-Alcoholic" 30252499 "The liver-specific microRNAs including miR-122, miR-130,miR-183, miR-196, miR-209 and miR-96 are potential indicators of liver injury" circulation_biomarker_diagnosis_ns hsa-mir-183 "Fatty Liver, Non-Alcoholic" 30252499 "The liver-specific microRNAs including miR-122, miR-130,miR-183, miR-196, miR-209 and miR-96 are potential indicators of liver injury" circulation_biomarker_diagnosis_ns hsa-mir-196 "Fatty Liver, Non-Alcoholic" 30252499 "The liver-specific microRNAs including miR-122, miR-130,miR-183, miR-196, miR-209 and miR-96 are potential indicators of liver injury" circulation_biomarker_diagnosis_ns hsa-mir-209 "Fatty Liver, Non-Alcoholic" 30252499 "The liver-specific microRNAs including miR-122, miR-130,miR-183, miR-196, miR-209 and miR-96 are potential indicators of liver injury" circulation_biomarker_diagnosis_ns hsa-mir-96 "Fatty Liver, Non-Alcoholic" 30252499 "The liver-specific microRNAs including miR-122, miR-130,miR-183, miR-196, miR-209 and miR-96 are potential indicators of liver injury" circulation_biomarker_diagnosis_ns hsa-mir-183 "Carcinoma, Hepatocellular" 30256056 Expression Analysis of Serum microRNA-34a and microRNA-183 in Hepatocellular Carcinoma circulation_biomarker_diagnosis_ns hsa-mir-34a "Carcinoma, Hepatocellular" 30256056 Expression Analysis of Serum microRNA-34a and microRNA-183 in Hepatocellular Carcinoma circulation_biomarker_diagnosis_ns hsa-mir-22 Myocardial Infarction 30256407 Circulating miR-22-5p and miR-122-5p are promising novel biomarkers for diagnosis of acute myocardial infarction. circulation_biomarker_diagnosis_ns hsa-mir-22 Myocardial Infarction 30256407 Circulating miR-22-5p and miR-122-5p are promising novel biomarkers for diagnosis of acute myocardial infarction. circulation_biomarker_diagnosis_ns hsa-mir-199a Diabetes Mellitus 30258406 "Diabetes Modulates MicroRNAs 29b-3p, 29c-3p, 199a-5p and 532-3p Expression in Muscle: Possible Role in GLUT4 and HK2 Repression." circulation_biomarker_diagnosis_ns hsa-mir-29b Diabetes Mellitus 30258406 "Diabetes Modulates MicroRNAs 29b-3p, 29c-3p, 199a-5p and 532-3p Expression in Muscle: Possible Role in GLUT4 and HK2 Repression." circulation_biomarker_diagnosis_ns hsa-mir-29c Diabetes Mellitus 30258406 "Diabetes Modulates MicroRNAs 29b-3p, 29c-3p, 199a-5p and 532-3p Expression in Muscle: Possible Role in GLUT4 and HK2 Repression." circulation_biomarker_diagnosis_ns hsa-mir-532 Diabetes Mellitus 30258406 "Diabetes Modulates MicroRNAs 29b-3p, 29c-3p, 199a-5p and 532-3p Expression in Muscle: Possible Role in GLUT4 and HK2 Repression." circulation_biomarker_diagnosis_ns hsa-let-7g "Diabetes Mellitus, Type 1" 30259606 Temporal dynamics of serum let-7g expression mirror the decline of residual beta-cell function in longitudinal observation of children with type 1 diabetes. circulation_biomarker_diagnosis_ns hsa-mir-136 Preeclampsia 30261165 "Role of mesenchymal stem cells exosomes derived microRNAs; miR-136, miR-494 and miR-495 in pre-eclampsia diagnosis and evaluation." circulation_biomarker_diagnosis_ns hsa-mir-494 Preeclampsia 30261165 "Role of mesenchymal stem cells exosomes derived microRNAs; miR-136, miR-494 and miR-495 in pre-eclampsia diagnosis and evaluation." circulation_biomarker_diagnosis_ns hsa-mir-495 Preeclampsia 30261165 "Role of mesenchymal stem cells exosomes derived microRNAs; miR-136, miR-494 and miR-495 in pre-eclampsia diagnosis and evaluation." circulation_biomarker_diagnosis_ns hsa-mir-200 Ovarian Neoplasms 30275195 Increased Soluble PD-L1 Levels in the Plasma of Patients with Epithelial Ovarian Cancer Correlate with Plasma Levels of miR34a and miR200. circulation_biomarker_diagnosis_ns hsa-mir-34a Ovarian Neoplasms 30275195 Increased Soluble PD-L1 Levels in the Plasma of Patients with Epithelial Ovarian Cancer Correlate with Plasma Levels of miR34a and miR200. circulation_biomarker_diagnosis_ns hsa-mir-142a Myocardial Infarction 30279543 A novel system-level approach using RNA-sequencing data identifies miR-30-5p and miR-142a-5p as key regulators of apoptosis in myocardial infarction. circulation_biomarker_diagnosis_ns hsa-mir-30 Myocardial Infarction 30279543 A novel system-level approach using RNA-sequencing data identifies miR-30-5p and miR-142a-5p as key regulators of apoptosis in myocardial infarction. circulation_biomarker_diagnosis_ns hsa-mir-210 "Carcinoma, Renal Cell, Clear-Cell" 30304555 Serum exosomal miR-210 as a potential biomarker for clear cell renal cell carcinoma. circulation_biomarker_diagnosis_ns hsa-mir-371b Systemic Lupus Erythematosus 30304699 Serum miRNA-371b-5p and miRNA-5100 act as biomarkers for systemic lupus erythematosus. circulation_biomarker_diagnosis_ns hsa-mir-5100 Systemic Lupus Erythematosus 30304699 Serum miRNA-371b-5p and miRNA-5100 act as biomarkers for systemic lupus erythematosus. circulation_biomarker_diagnosis_ns hsa-mir-146a Lupus Nephritis 30306067 "miR-3135b, miR-654-5p and miR-146a-5p in urinary exosomes could be used as novel non-invasive diagnostic markers for LNIV-CC" circulation_biomarker_diagnosis_ns hsa-mir-3135b Lupus Nephritis 30306067 "miR-3135b, miR-654-5p and miR-146a-5p in urinary exosomes could be used as novel non-invasive diagnostic markers for LNIV-CC" circulation_biomarker_diagnosis_ns hsa-mir-654 Lupus Nephritis 30306067 "miR-3135b, miR-654-5p and miR-146a-5p in urinary exosomes could be used as novel non-invasive diagnostic markers for LNIV-CC" circulation_biomarker_diagnosis_ns hsa-mir-29c Atherosclerosis 30308507 Plasma MicroRNA-29c Levels Are Associated with Carotid Intima-Media Thickness and is a Potential Biomarker for the Early Detection of Atherosclerosis. circulation_biomarker_diagnosis_ns hsa-mir-1254 Myocardial Infarction 30310086 Circulating miR-1254 predicts ventricular remodeling in patients with ST-Segment-Elevation Myocardial Infarction: A cardiovascular magnetic resonance study. circulation_biomarker_diagnosis_ns hsa-mir-142a Alzheimer Disease 30314521 "four of these (miR-142a-5p, miR-146a-5p, miR-155-5p and miR-455-5p) are altered in AD patients" circulation_biomarker_diagnosis_ns hsa-mir-146a Alzheimer Disease 30314521 "four of these (miR-142a-5p, miR-146a-5p, miR-155-5p and miR-455-5p) are altered in AD patients" circulation_biomarker_diagnosis_ns hsa-mir-155 Alzheimer Disease 30314521 "four of these (miR-142a-5p, miR-146a-5p, miR-155-5p and miR-455-5p) are altered in AD patients" circulation_biomarker_diagnosis_ns hsa-mir-455 Alzheimer Disease 30314521 "four of these (miR-142a-5p, miR-146a-5p, miR-155-5p and miR-455-5p) are altered in AD patients" circulation_biomarker_diagnosis_ns hsa-mir-2166 "Stroke, Ischemic" 30316639 "Ten of these miRNA had not previously been associated with ischemic stroke (miR-664a-3p, -2116-5pp, -4531, -4765-5p, -647, -4709-3p, -4742-3p, -5584-3p, -4756-3p, and -5187-3p)" circulation_biomarker_diagnosis_ns hsa-mir-4531 "Stroke, Ischemic" 30316639 "Ten of these miRNA had not previously been associated with ischemic stroke (miR-664a-3p, -2116-5pp, -4531, -4765-5p, -647, -4709-3p, -4742-3p, -5584-3p, -4756-3p, and -5187-3p)" circulation_biomarker_diagnosis_ns hsa-mir-4709 "Stroke, Ischemic" 30316639 "Ten of these miRNA had not previously been associated with ischemic stroke (miR-664a-3p, -2116-5pp, -4531, -4765-5p, -647, -4709-3p, -4742-3p, -5584-3p, -4756-3p, and -5187-3p)" circulation_biomarker_diagnosis_ns hsa-mir-4742 "Stroke, Ischemic" 30316639 "Ten of these miRNA had not previously been associated with ischemic stroke (miR-664a-3p, -2116-5pp, -4531, -4765-5p, -647, -4709-3p, -4742-3p, -5584-3p, -4756-3p, and -5187-3p)" circulation_biomarker_diagnosis_ns hsa-mir-4756 "Stroke, Ischemic" 30316639 "Ten of these miRNA had not previously been associated with ischemic stroke (miR-664a-3p, -2116-5pp, -4531, -4765-5p, -647, -4709-3p, -4742-3p, -5584-3p, -4756-3p, and -5187-3p)" circulation_biomarker_diagnosis_ns hsa-mir-4765 "Stroke, Ischemic" 30316639 "Ten of these miRNA had not previously been associated with ischemic stroke (miR-664a-3p, -2116-5pp, -4531, -4765-5p, -647, -4709-3p, -4742-3p, -5584-3p, -4756-3p, and -5187-3p)" circulation_biomarker_diagnosis_ns hsa-mir-5187 "Stroke, Ischemic" 30316639 "Ten of these miRNA had not previously been associated with ischemic stroke (miR-664a-3p, -2116-5pp, -4531, -4765-5p, -647, -4709-3p, -4742-3p, -5584-3p, -4756-3p, and -5187-3p)" circulation_biomarker_diagnosis_ns hsa-mir-5584 "Stroke, Ischemic" 30316639 "Ten of these miRNA had not previously been associated with ischemic stroke (miR-664a-3p, -2116-5pp, -4531, -4765-5p, -647, -4709-3p, -4742-3p, -5584-3p, -4756-3p, and -5187-3p)" circulation_biomarker_diagnosis_ns hsa-mir-647 "Stroke, Ischemic" 30316639 "Ten of these miRNA had not previously been associated with ischemic stroke (miR-664a-3p, -2116-5pp, -4531, -4765-5p, -647, -4709-3p, -4742-3p, -5584-3p, -4756-3p, and -5187-3p)" circulation_biomarker_diagnosis_ns hsa-mir-664a "Stroke, Ischemic" 30316639 "Ten of these miRNA had not previously been associated with ischemic stroke (miR-664a-3p, -2116-5pp, -4531, -4765-5p, -647, -4709-3p, -4742-3p, -5584-3p, -4756-3p, and -5187-3p)" circulation_biomarker_diagnosis_ns hsa-mir-371a Testicular Germ Cell Tumor 30321995 MiR-371a-3p Serum Levels Are Increased in Recurrence of Testicular Germ Cell Tumor Patients. circulation_biomarker_diagnosis_ns hsa-mir-210 Preeclampsia 30324123 miR-210 could serve as a novel biomarker to predict PE pathophysiology circulation_biomarker_diagnosis_ns hsa-let-7b Prostate Neoplasms 30324582 "miR-1825, miR-484, miR-205, miR-141, and let-7b were shown to be highly specific for PCa" circulation_biomarker_diagnosis_ns hsa-mir-141 Prostate Neoplasms 30324582 "miR-1825, miR-484, miR-205, miR-141, and let-7b were shown to be highly specific for PCa" circulation_biomarker_diagnosis_ns hsa-mir-1825 Prostate Neoplasms 30324582 "miR-1825, miR-484, miR-205, miR-141, and let-7b were shown to be highly specific for PCa" circulation_biomarker_diagnosis_ns hsa-mir-205 Prostate Neoplasms 30324582 "miR-1825, miR-484, miR-205, miR-141, and let-7b were shown to be highly specific for PCa" circulation_biomarker_diagnosis_ns hsa-mir-484 Prostate Neoplasms 30324582 "miR-1825, miR-484, miR-205, miR-141, and let-7b were shown to be highly specific for PCa" circulation_biomarker_diagnosis_ns hsa-mir-143 Sepsis 30332984 MicroRNAs 143 and 150 in whole blood enable detection of T-cell immunoparalysis in sepsis. circulation_biomarker_diagnosis_ns hsa-mir-150 Sepsis 30332984 MicroRNAs 143 and 150 in whole blood enable detection of T-cell immunoparalysis in sepsis. circulation_biomarker_diagnosis_ns hsa-mir-10a Vascular Myelopathy 30352301 "MicroRNA-10a, -210 and -563 as circulating biomarkers for Ossification of the Posterior Longitudinal Ligament." circulation_biomarker_diagnosis_ns hsa-mir-210 Vascular Myelopathy 30352301 "MicroRNA-10a, -210 and -563 as circulating biomarkers for Ossification of the Posterior Longitudinal Ligament." circulation_biomarker_diagnosis_ns hsa-mir-563 Vascular Myelopathy 30352301 "MicroRNA-10a, -210 and -563 as circulating biomarkers for Ossification of the Posterior Longitudinal Ligament." circulation_biomarker_diagnosis_ns hsa-mir-3177 Aneurysmal Subarachnoid Hemorrhage 30354977 whole-blood miRNA levels of hsa-miR-3177-3p could serve as a biomarker for vasospasm circulation_biomarker_diagnosis_ns hsa-mir-126 Colorectal Carcinoma 30357530 "Role of miRNA-210, miRNA-21 and miRNA-126 as diagnostic biomarkers in colorectal carcinoma: impact of HIF-1¦Á-VEGF signaling pathway." circulation_biomarker_diagnosis_ns hsa-mir-21 Colorectal Carcinoma 30357530 "Role of miRNA-210, miRNA-21 and miRNA-126 as diagnostic biomarkers in colorectal carcinoma: impact of HIF-1¦Á-VEGF signaling pathway." circulation_biomarker_diagnosis_ns hsa-mir-210 Colorectal Carcinoma 30357530 "Role of miRNA-210, miRNA-21 and miRNA-126 as diagnostic biomarkers in colorectal carcinoma: impact of HIF-1¦Á-VEGF signaling pathway." circulation_biomarker_diagnosis_ns hsa-mir-128 Huntington Disease 30359470 "hsa-miR-338-3p, hsa-miR-128-3p, hsa-miR-23a-3p and hsa-miR-24-3p are potential HD-biomarkers" circulation_biomarker_diagnosis_ns hsa-mir-23a Huntington Disease 30359470 "hsa-miR-338-3p, hsa-miR-128-3p, hsa-miR-23a-3p and hsa-miR-24-3p are potential HD-biomarkers" circulation_biomarker_diagnosis_ns hsa-mir-24 Huntington Disease 30359470 "hsa-miR-338-3p, hsa-miR-128-3p, hsa-miR-23a-3p and hsa-miR-24-3p are potential HD-biomarkers" circulation_biomarker_diagnosis_ns hsa-mir-338 Huntington Disease 30359470 "hsa-miR-338-3p, hsa-miR-128-3p, hsa-miR-23a-3p and hsa-miR-24-3p are potential HD-biomarkers" circulation_biomarker_diagnosis_ns hsa-mir-122 Gastric Neoplasms 30364858 miR-122-5p as a novel biomarker for alpha-fetoprotein-producing gastric cancer. circulation_biomarker_diagnosis_ns hsa-mir-142 Gastric Neoplasms 30373600 miR-338-3p and miR-142-3p may be promising predictive biomarkers for such patients circulation_biomarker_diagnosis_ns hsa-mir-338 Gastric Neoplasms 30373600 miR-338-3p and miR-142-3p may be promising predictive biomarkers for such patients circulation_biomarker_diagnosis_ns hsa-mir-1185-1 "Carcinoma, Bladder" 30382619 Circulating miRNA Panels for Specific and Early Detection in Bladder Cancer. circulation_biomarker_diagnosis_ns hsa-mir-1343 "Carcinoma, Bladder" 30382619 Circulating miRNA Panels for Specific and Early Detection in Bladder Cancer. circulation_biomarker_diagnosis_ns hsa-mir-3960 "Carcinoma, Bladder" 30382619 Circulating miRNA Panels for Specific and Early Detection in Bladder Cancer. circulation_biomarker_diagnosis_ns hsa-mir-4695 "Carcinoma, Bladder" 30382619 Circulating miRNA Panels for Specific and Early Detection in Bladder Cancer. circulation_biomarker_diagnosis_ns hsa-mir-6087 "Carcinoma, Bladder" 30382619 Circulating miRNA Panels for Specific and Early Detection in Bladder Cancer. circulation_biomarker_diagnosis_ns hsa-mir-6724 "Carcinoma, Bladder" 30382619 Circulating miRNA Panels for Specific and Early Detection in Bladder Cancer. circulation_biomarker_diagnosis_ns hsa-mir-6831 "Carcinoma, Bladder" 30382619 Circulating miRNA Panels for Specific and Early Detection in Bladder Cancer. circulation_biomarker_diagnosis_up hsa-mir-155 "Lymphoma, Burkitt" 14695998 upregulated circulation_biomarker_diagnosis_up hsa-mir-155 "Lymphoma, B-Cell" 15738415 upregulated circulation_biomarker_diagnosis_up hsa-mir-155 "Lymphoma, Burkitt" 16195701 overexpression circulation_biomarker_diagnosis_up hsa-mir-17 "Leukemia, B-Cell" 16224045 Overexpression circulation_biomarker_diagnosis_up hsa-mir-18a "Leukemia, B-Cell" 16224045 Overexpression circulation_biomarker_diagnosis_up hsa-mir-19a "Leukemia, B-Cell" 16224045 Overexpression circulation_biomarker_diagnosis_up hsa-mir-19b-1 "Leukemia, B-Cell" 16224045 Overexpression circulation_biomarker_diagnosis_up hsa-mir-20a "Leukemia, B-Cell" 16224045 Overexpression circulation_biomarker_diagnosis_up hsa-mir-92a-1 "Leukemia, B-Cell" 16224045 Overexpression circulation_biomarker_diagnosis_up hsa-mir-146a "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 overexpression circulation_biomarker_diagnosis_up hsa-mir-146b "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 overexpression circulation_biomarker_diagnosis_up hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 overexpression circulation_biomarker_diagnosis_up hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 overexpression circulation_biomarker_diagnosis_up hsa-mir-195 "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 overexpression circulation_biomarker_diagnosis_up hsa-mir-221 "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 overexpression circulation_biomarker_diagnosis_up hsa-mir-23b "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 overexpression circulation_biomarker_diagnosis_up hsa-mir-24-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 overexpression circulation_biomarker_diagnosis_up hsa-mir-17 Lung Neoplasms 16266980 overexpressed circulation_biomarker_diagnosis_up hsa-mir-18a Lung Neoplasms 16266980 overexpressed circulation_biomarker_diagnosis_up hsa-mir-19a Lung Neoplasms 16266980 overexpressed circulation_biomarker_diagnosis_up hsa-mir-19b-1 Lung Neoplasms 16266980 overexpressed circulation_biomarker_diagnosis_up hsa-mir-20a Lung Neoplasms 16266980 overexpressed circulation_biomarker_diagnosis_up hsa-mir-92a-1 Lung Neoplasms 16266980 overexpressed circulation_biomarker_diagnosis_up hsa-mir-155 Breast Neoplasms 16466964 overexpressed circulation_biomarker_diagnosis_up hsa-mir-155 "Leukemia, B-Cell" 16466964 overexpressed circulation_biomarker_diagnosis_up hsa-mir-155 "Lymphoma, Burkitt" 16466964 overexpressed circulation_biomarker_diagnosis_up hsa-mir-155 "Lymphoma, Hodgkin" 16466964 overexpressed circulation_biomarker_diagnosis_up hsa-mir-21 Brain Neoplasms 16466964 overexpressed circulation_biomarker_diagnosis_up hsa-mir-21 Glioblastoma 16466964 overexpressed circulation_biomarker_diagnosis_up hsa-mir-155 "Leukemia, B-Cell" 16736018 upregulation of miR-155 and the miR-17-92 cluster circulation_biomarker_diagnosis_up hsa-mir-17 "Leukemia, B-Cell" 16736018 upregulation of miR-155 and the miR-17-92 cluster circulation_biomarker_diagnosis_up hsa-mir-18a "Leukemia, B-Cell" 16736018 upregulation of miR-155 and the miR-17-92 cluster circulation_biomarker_diagnosis_up hsa-mir-19a "Leukemia, B-Cell" 16736018 upregulation of miR-155 and the miR-17-92 cluster circulation_biomarker_diagnosis_up hsa-mir-19b-1 "Leukemia, B-Cell" 16736018 upregulation of miR-155 and the miR-17-92 cluster circulation_biomarker_diagnosis_up hsa-mir-20a "Leukemia, B-Cell" 16736018 upregulation of miR-155 and the miR-17-92 cluster circulation_biomarker_diagnosis_up hsa-mir-92a-1 "Leukemia, B-Cell" 16736018 upregulation of miR-155 and the miR-17-92 cluster circulation_biomarker_diagnosis_up hsa-mir-127 Breast Neoplasms 16766263 upregulation circulation_biomarker_diagnosis_up hsa-mir-145 Colon Neoplasms 16885332 Reduced accumulation in colon adenomas and carcinomas circulation_biomarker_diagnosis_up hsa-mir-146a Thyroid Neoplasms 16885332 up-regulation circulation_biomarker_diagnosis_up hsa-mir-146b Thyroid Neoplasms 16885332 up-regulation circulation_biomarker_diagnosis_up hsa-mir-155 Breast Neoplasms 16885332 Overexpression in breast cancers circulation_biomarker_diagnosis_up hsa-mir-17 Lung Neoplasms 16885332 Overexpressed in lung cancers circulation_biomarker_diagnosis_up hsa-mir-17 Lymphoma 16885332 Primary transcripts overexpressed in lymphomas circulation_biomarker_diagnosis_up hsa-mir-18a Lung Neoplasms 16885332 Overexpressed in lung cancers circulation_biomarker_diagnosis_up hsa-mir-18a Lymphoma 16885332 Primary transcripts overexpressed in lymphomas circulation_biomarker_diagnosis_up hsa-mir-19a Lung Neoplasms 16885332 Overexpressed in lung cancers circulation_biomarker_diagnosis_up hsa-mir-19a Lymphoma 16885332 Primary transcripts overexpressed in lymphomas circulation_biomarker_diagnosis_up hsa-mir-19b-1 Lung Neoplasms 16885332 Overexpressed in lung cancers circulation_biomarker_diagnosis_up hsa-mir-19b-1 Lymphoma 16885332 Primary transcripts overexpressed in lymphomas circulation_biomarker_diagnosis_up hsa-mir-20a Lung Neoplasms 16885332 Overexpressed in lung cancers circulation_biomarker_diagnosis_up hsa-mir-20a Lymphoma 16885332 Primary transcripts overexpressed in lymphomas circulation_biomarker_diagnosis_up hsa-mir-21 Breast Neoplasms 16885332 Overexpression in breast cancers circulation_biomarker_diagnosis_up hsa-mir-21 Glioblastoma 16885332 Elevated levels in glioblastoma primary tumors and cell lines circulation_biomarker_diagnosis_up hsa-mir-221 Thyroid Neoplasms 16885332 "It was shown that miR-221, highly overexpressed in papillary thyroid tumors, is also overexpressed in normal thyroid tissue adjacent to tumors but not in normal thyroid tissues from individuals without clinical thyroid disease." circulation_biomarker_diagnosis_up hsa-mir-222 Thyroid Neoplasms 16885332 up-regulation circulation_biomarker_diagnosis_up hsa-mir-92a-1 Lung Neoplasms 16885332 Overexpressed in lung cancers circulation_biomarker_diagnosis_up hsa-mir-92a-1 Lymphoma 16885332 Primary transcripts overexpressed in lymphomas circulation_biomarker_diagnosis_up hsa-mir-155 "Lymphoma, Burkitt" 16940181 Increased expression of the precursor of Mir-155has been detected in pediatric Burkitt lymphoma. circulation_biomarker_diagnosis_up hsa-mir-21 Glioblastoma 17028302 "miR-21 is strongly overexpressed in this highly malignant brain tumor type, while knockdown of miR-21 in glioblastoma cells by an antisense-oligonucleotide triggered activation of caspases and led to increased apoptotic cell death, suggesting that miR-21 overexpression may contribute to the malignant phenotype by suppressing critical apoptosis-related genes." circulation_biomarker_diagnosis_up hsa-mir-17 Neoplasms [unspecific] 17060945 overexpressed circulation_biomarker_diagnosis_up hsa-mir-191 Neoplasms [unspecific] 17060945 overexpressed circulation_biomarker_diagnosis_up hsa-mir-17 Neoplasms [unspecific] 17189674 "Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer." circulation_biomarker_diagnosis_up hsa-mir-18a Neoplasms [unspecific] 17189674 "Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17§Ò§ÙC19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer." circulation_biomarker_diagnosis_up hsa-mir-18b Neoplasms [unspecific] 17189674 "Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17§Ò§ÙC19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer." circulation_biomarker_diagnosis_up hsa-mir-19a Neoplasms [unspecific] 17189674 "Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17§Ò§ÙC19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer." circulation_biomarker_diagnosis_up hsa-mir-19b-1 Neoplasms [unspecific] 17189674 "Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17§Ò§ÙC19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer." circulation_biomarker_diagnosis_up hsa-mir-19b-2 Neoplasms [unspecific] 17189674 "Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17§Ò§ÙC19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer." circulation_biomarker_diagnosis_up hsa-mir-20a Neoplasms [unspecific] 17189674 "Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17§Ò§ÙC19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer." circulation_biomarker_diagnosis_up hsa-mir-20b Neoplasms [unspecific] 17189674 "Co-expression of a cluster of miRNAs derived from one genomic locus (miR-17, -18, -19, and -20) caused a significant acceleration of tumorigenesis in a c-Myc driven mouse model of lymphomagenesis. The miR-17§Ò§ÙC19 cluster for instance was found to be highly expressed in follicular lymphoma, low grade B cell malignancy , several types of lymphoma and solid tumors and small cell lung cancer." circulation_biomarker_diagnosis_up hsa-mir-372 Testicular Neoplasms 17189674 "The relevance to human tumorigenesis was shown when it was found that these miRNAs are hyper-expressed in Testicular Germ Cell Tumors, a tumor type characterized by its prevalence of wild type p53." circulation_biomarker_diagnosis_up hsa-mir-373 Testicular Neoplasms 17189674 "The relevance to human tumorigenesis was shown when it was found that these miRNAs are hyper-expressed in Testicular Germ Cell Tumors, a tumor type characterized by its prevalence of wild type p53." circulation_biomarker_diagnosis_up hsa-let-7a-3 "Leukemia, Promyelocytic, Acute" 17260024 "We found upregulation of miR-15a, miR-15b, miR-16-1, let-7a-3, let-7c, let-7d, miR-223, miR-342 and miR-107, whereas miR-181b was downregulated. Among the upregulated miRNAs, miR-107 is predicted to target NFI-A, a gene that has been involved in a regulatory loop involving miR-223 and C/EBPa during granulocytic differentiation." circulation_biomarker_diagnosis_up hsa-let-7c "Leukemia, Promyelocytic, Acute" 17260024 "We found upregulation of miR-15a, miR-15b, miR-16-1, let-7a-3, let-7c, let-7d, miR-223, miR-342 and miR-107, whereas miR-181b was downregulated. Among the upregulated miRNAs, miR-107 is predicted to target NFI-A, a gene that has been involved in a regulatory loop involving miR-223 and C/EBPa during granulocytic differentiation." circulation_biomarker_diagnosis_up hsa-let-7d "Leukemia, Promyelocytic, Acute" 17260024 "We found upregulation of miR-15a, miR-15b, miR-16-1, let-7a-3, let-7c, let-7d, miR-223, miR-342 and miR-107, whereas miR-181b was downregulated. Among the upregulated miRNAs, miR-107 is predicted to target NFI-A, a gene that has been involved in a regulatory loop involving miR-223 and C/EBPa during granulocytic differentiation." circulation_biomarker_diagnosis_up hsa-mir-107 "Leukemia, Promyelocytic, Acute" 17260024 "We found upregulation of miR-15a, miR-15b, miR-16-1, let-7a-3, let-7c, let-7d, miR-223, miR-342 and miR-107, whereas miR-181b was downregulated. Among the upregulated miRNAs, miR-107 is predicted to target NFI-A, a gene that has been involved in a regulatory loop involving miR-223 and C/EBPa during granulocytic differentiation." circulation_biomarker_diagnosis_up hsa-mir-15a "Leukemia, Promyelocytic, Acute" 17260024 "We found upregulation of miR-15a, miR-15b, miR-16-1, let-7a-3, let-7c, let-7d, miR-223, miR-342 and miR-107, whereas miR-181b was downregulated. Among the upregulated miRNAs, miR-107 is predicted to target NFI-A, a gene that has been involved in a regulatory loop involving miR-223 and C/EBPa during granulocytic differentiation." circulation_biomarker_diagnosis_up hsa-mir-15b "Leukemia, Promyelocytic, Acute" 17260024 "We found upregulation of miR-15a, miR-15b, miR-16-1, let-7a-3, let-7c, let-7d, miR-223, miR-342 and miR-107, whereas miR-181b was downregulated. Among the upregulated miRNAs, miR-107 is predicted to target NFI-A, a gene that has been involved in a regulatory loop involving miR-223 and C/EBPa during granulocytic differentiation." circulation_biomarker_diagnosis_up hsa-mir-16-1 "Leukemia, Promyelocytic, Acute" 17260024 "We found upregulation of miR-15a, miR-15b, miR-16-1, let-7a-3, let-7c, let-7d, miR-223, miR-342 and miR-107, whereas miR-181b was downregulated. Among the upregulated miRNAs, miR-107 is predicted to target NFI-A, a gene that has been involved in a regulatory loop involving miR-223 and C/EBPa during granulocytic differentiation." circulation_biomarker_diagnosis_up hsa-mir-223 "Leukemia, Promyelocytic, Acute" 17260024 "We found upregulation of miR-15a, miR-15b, miR-16-1, let-7a-3, let-7c, let-7d, miR-223, miR-342 and miR-107, whereas miR-181b was downregulated. Among the upregulated miRNAs, miR-107 is predicted to target NFI-A, a gene that has been involved in a regulatory loop involving miR-223 and C/EBPa during granulocytic differentiation." circulation_biomarker_diagnosis_up hsa-mir-342 "Leukemia, Promyelocytic, Acute" 17260024 "We found upregulation of miR-15a, miR-15b, miR-16-1, let-7a-3, let-7c, let-7d, miR-223, miR-342 and miR-107, whereas miR-181b was downregulated. Among the upregulated miRNAs, miR-107 is predicted to target NFI-A, a gene that has been involved in a regulatory loop involving miR-223 and C/EBPa during granulocytic differentiation." circulation_biomarker_diagnosis_up hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 17327404 "Both approaches show that miR-21 and miR-155 are dramatically overexpressed in patients with CLL, although the corresponding genomic loci are not amplified. miR-150 and miR-92 are also significantly deregulated in patients with CLL. In addition, we detected a marked miR-15a and miR-16 decrease in about 11% of cases" circulation_biomarker_diagnosis_up hsa-mir-21 "Leukemia, Lymphocytic, Chronic, B-Cell" 17327404 "Both approaches show that miR-21 and miR-155 are dramatically overexpressed in patients with CLL, although the corresponding genomic loci are not amplified. miR-150 and miR-92 are also significantly deregulated in patients with CLL. In addition, we detected a marked miR-15a and miR-16 decrease in about 11% of cases" circulation_biomarker_diagnosis_up hsa-mir-141 Cholangiocarcinoma 17355635 These include miR-200b and miR-141 which have been shown to be highly overexpressed in malignant cholangiocytes and in colon carcinoma. circulation_biomarker_diagnosis_up hsa-mir-141 Colon Neoplasms 17355635 These include miR-200b and miR-141 which have been shown to be highly overexpressed in malignant cholangiocytes and in colon carcinoma. circulation_biomarker_diagnosis_up hsa-mir-146a Thyroid Neoplasms 17355635 "Recent studies in miRNA deregulation PTC found an aberrant miRNA expression profile in PTCs compared to normal thyroid tissues. In particular, a significant increase in mir-222, mir-221, mir-146." circulation_biomarker_diagnosis_up hsa-mir-146b Thyroid Neoplasms 17355635 "Recent studies in miRNA deregulation PTC found an aberrant miRNA expression profile in PTCs compared to normal thyroid tissues. In particular, a significant increase in mir-222, mir-221, mir-146." circulation_biomarker_diagnosis_up hsa-mir-200a Thyroid Neoplasms 17355635 "Three of these upregulated miRNAs showed significantly higher fold change than the other upregulated miRNAs, these are mir-200a, mir-200b and mir-141." circulation_biomarker_diagnosis_up hsa-mir-200b Cholangiocarcinoma 17355635 These include miR-200b and miR-141 which have been shown to be highly overexpressed in malignant cholangiocytes and in colon carcinoma. circulation_biomarker_diagnosis_up hsa-mir-200b Colon Neoplasms 17355635 These include miR-200b and miR-141 which have been shown to be highly overexpressed in malignant cholangiocytes and in colon carcinoma. circulation_biomarker_diagnosis_up hsa-mir-200b Thyroid Neoplasms 17355635 "Three of these upregulated miRNAs showed significantly higher fold change than the other upregulated miRNAs, these are mir-200a, mir-200b and mir-141." circulation_biomarker_diagnosis_up hsa-mir-221 Thyroid Neoplasms 17355635 "Recent studies in miRNA deregulation PTC found an aberrant miRNA expression profile in PTCs compared to normal thyroid tissues. In particular, a significant increase in mir-222, mir-221, mir-146." circulation_biomarker_diagnosis_up hsa-mir-222 Thyroid Neoplasms 17355635 "Recent studies in miRNA deregulation PTC found an aberrant miRNA expression profile in PTCs compared to normal thyroid tissues. In particular, a significant increase in mir-222, mir-221, mir-146." circulation_biomarker_diagnosis_up hsa-mir-208a Heart Failure 17379774 upregulation circulation_biomarker_diagnosis_up hsa-mir-106a Colon Neoplasms 17442096 "Indeed, in human solid tumors, mir-106a expression is increased in colon, pancreas, and prostate tumors." circulation_biomarker_diagnosis_up hsa-mir-106a Pancreatic Neoplasms 17442096 "Indeed, in human solid tumors, mir-106a expression is increased in colon, pancreas, and prostate tumors." circulation_biomarker_diagnosis_up hsa-mir-106a Prostate Neoplasms 17442096 "Indeed, in human solid tumors, mir-106a expression is increased in colon, pancreas, and prostate tumors." circulation_biomarker_diagnosis_up hsa-mir-17 Lung Neoplasms 17442096 The mir-17 cluster is also overexpressed in human lung cancer. circulation_biomarker_diagnosis_up hsa-mir-132 Breast Neoplasms 17447837 "miR-132, previously shown to be differentially upregulated in six solid cancer types (breast, colon, lung, pancreas, prostate, and stomach carcinomas)" circulation_biomarker_diagnosis_up hsa-mir-132 Colon Neoplasms 17447837 "miR-132, previously shown to be differentially upregulated in six solid cancer types (breast, colon, lung, pancreas, prostate, and stomach carcinomas)" circulation_biomarker_diagnosis_up hsa-mir-132 Gastric Neoplasms 17447837 "miR-132, previously shown to be differentially upregulated in six solid cancer types (breast, colon, lung, pancreas, prostate, and stomach carcinomas)" circulation_biomarker_diagnosis_up hsa-mir-132 Lung Neoplasms 17447837 "miR-132, previously shown to be differentially upregulated in six solid cancer types (breast, colon, lung, pancreas, prostate, and stomach carcinomas)" circulation_biomarker_diagnosis_up hsa-mir-132 Pancreatic Neoplasms 17447837 "miR-132, previously shown to be differentially upregulated in six solid cancer types (breast, colon, lung, pancreas, prostate, and stomach carcinomas)" circulation_biomarker_diagnosis_up hsa-mir-132 Prostate Neoplasms 17447837 "miR-132, previously shown to be differentially upregulated in six solid cancer types (breast, colon, lung, pancreas, prostate, and stomach carcinomas)" circulation_biomarker_diagnosis_up hsa-mir-21 Focal Epithelial Hyperplasia 17478730 We found that miR-21 was one of the most upregulated miRNAs in the vascular wall after balloon injury. Our results strongly indicate that miR-21 is an important regulator for neointimal hyperplasia. circulation_biomarker_diagnosis_up hsa-mir-155 "Lymphoma, Large B-Cell, Diffuse" 17487835 "DLBCL cases over-expressed miR-21, miR-155 and miR-221 by an average of 9.3, 4.6 and 2.3-fold respectively compared to normal peripheral blood B cells." circulation_biomarker_diagnosis_up hsa-mir-21 "Lymphoma, Large B-Cell, Diffuse" 17487835 "DLBCL cases over-expressed miR-21, miR-155 and miR-221 by an average of 9.3, 4.6 and 2.3-fold respectively compared to normal peripheral blood B cells." circulation_biomarker_diagnosis_up hsa-mir-221 "Lymphoma, Large B-Cell, Diffuse" 17487835 "DLBCL cases over-expressed miR-21, miR-155 and miR-221 by an average of 9.3, 4.6 and 2.3-fold respectively compared to normal peripheral blood B cells." circulation_biomarker_diagnosis_up hsa-mir-195 "Cardiomyopathy, Hypertrophic" 17786230 "Cardiac-specific overexpression of miRNA-195 (miR-195), which is consistently upregulated in rodent and human hypertrophic hearts, for example, results in dilated cardiomyopathy and heart failure in mice as early as two weeks of age, implying that upregulation of miR-195 during cardiac hypertrophy actively contributes to the disease process." circulation_biomarker_diagnosis_up hsa-mir-1-1 Coronary Artery Disease 17919180 elevated expression circulation_biomarker_diagnosis_up hsa-mir-1-2 Coronary Artery Disease 17919180 elevated expression circulation_biomarker_diagnosis_up hsa-mir-128b "Leukemia, Lymphoblastic, Acute" 17934639 "The five most highly expressed miRNAs were miR-128b, miR-204, miR-218, miR-331, and miR-181b-1 in ALL, and miR-331, miR-29a, miR-195, miR-34a, and miR-29c in CLL." circulation_biomarker_diagnosis_up hsa-mir-17 "Leukemia, Lymphoblastic, Acute" 17934639 "The miR-17-92 cluster was also found to be up-regulated in ALL, as previously reported for some types of lymphomas." circulation_biomarker_diagnosis_up hsa-mir-18 "Leukemia, Lymphoblastic, Acute" 17934639 "The miR-17-92 cluster was also found to be up-regulated in ALL, as previously reported for some types of lymphomas." circulation_biomarker_diagnosis_up hsa-mir-181b-1 "Leukemia, Lymphoblastic, Acute" 17934639 "The five most highly expressed miRNAs were miR-128b, miR-204, miR-218, miR-331, and miR-181b-1 in ALL, and miR-331, miR-29a, miR-195, miR-34a, and miR-29c in CLL." circulation_biomarker_diagnosis_up hsa-mir-195 "Leukemia, Lymphocytic, Chronic, B-Cell" 17934639 "The five most highly expressed miRNAs were miR-128b, miR-204, miR-218, miR-331, and miR-181b-1 in ALL, and miR-331, miR-29a, miR-195, miR-34a, and miR-29c in CLL." circulation_biomarker_diagnosis_up hsa-mir-19a "Leukemia, Lymphoblastic, Acute" 17934639 "The miR-17-92 cluster was also found to be up-regulated in ALL, as previously reported for some types of lymphomas." circulation_biomarker_diagnosis_up hsa-mir-19b-1 "Leukemia, Lymphoblastic, Acute" 17934639 "The miR-17-92 cluster was also found to be up-regulated in ALL, as previously reported for some types of lymphomas." circulation_biomarker_diagnosis_up hsa-mir-204 "Leukemia, Lymphoblastic, Acute" 17934639 "The five most highly expressed miRNAs were miR-128b, miR-204, miR-218, miR-331, and miR-181b-1 in ALL, and miR-331, miR-29a, miR-195, miR-34a, and miR-29c in CLL." circulation_biomarker_diagnosis_up hsa-mir-20a "Leukemia, Lymphoblastic, Acute" 17934639 "The miR-17-92 cluster was also found to be up-regulated in ALL, as previously reported for some types of lymphomas." circulation_biomarker_diagnosis_up hsa-mir-218 "Leukemia, Lymphoblastic, Acute" 17934639 "The five most highly expressed miRNAs were miR-128b, miR-204, miR-218, miR-331, and miR-181b-1 in ALL, and miR-331, miR-29a, miR-195, miR-34a, and miR-29c in CLL." circulation_biomarker_diagnosis_up hsa-mir-29a "Leukemia, Lymphocytic, Chronic, B-Cell" 17934639 "The five most highly expressed miRNAs were miR-128b, miR-204, miR-218, miR-331, and miR-181b-1 in ALL, and miR-331, miR-29a, miR-195, miR-34a, and miR-29c in CLL." circulation_biomarker_diagnosis_up hsa-mir-29c "Leukemia, Lymphocytic, Chronic, B-Cell" 17934639 "The five most highly expressed miRNAs were miR-128b, miR-204, miR-218, miR-331, and miR-181b-1 in ALL, and miR-331, miR-29a, miR-195, miR-34a, and miR-29c in CLL." circulation_biomarker_diagnosis_up hsa-mir-331 "Leukemia, Lymphoblastic, Acute" 17934639 "The five most highly expressed miRNAs were miR-128b, miR-204, miR-218, miR-331, and miR-181b-1 in ALL, and miR-331, miR-29a, miR-195, miR-34a, and miR-29c in CLL." circulation_biomarker_diagnosis_up hsa-mir-331 "Leukemia, Lymphocytic, Chronic, B-Cell" 17934639 "The five most highly expressed miRNAs were miR-128b, miR-204, miR-218, miR-331, and miR-181b-1 in ALL, and miR-331, miR-29a, miR-195, miR-34a, and miR-29c in CLL." circulation_biomarker_diagnosis_up hsa-mir-34a "Leukemia, Lymphocytic, Chronic, B-Cell" 17934639 "The five most highly expressed miRNAs were miR-128b, miR-204, miR-218, miR-331, and miR-181b-1 in ALL, and miR-331, miR-29a, miR-195, miR-34a, and miR-29c in CLL." circulation_biomarker_diagnosis_up hsa-mir-92-1 "Leukemia, Lymphoblastic, Acute" 17934639 "The miR-17-92 cluster was also found to be up-regulated in ALL, as previously reported for some types of lymphomas." circulation_biomarker_diagnosis_up hsa-mir-155 "Leukemia, B-Cell" 17940623 "miR-155 is encoded by nucleotides 241-262 of BIC, which was originally identified as a transcript derived from an integration site for the avian leucosis virus and found to be overexpressed in B-cell lymphomas. The role of miR-155 is not restricted to B cell lymphomas, however. Recent studies have reported that miR-155 is upregulated in breast, lung, colon, and thyroid cancers." circulation_biomarker_diagnosis_up hsa-mir-1-1 "Cardiomyopathy, Hypertrophic" 17965831 "miR-1 is overexpressed in patients with coronary artery disease and that overexpression of miR-1 in a rat model of cardiac infarction exacerbated arrhythmogenesis. Cardiac hypertrophy may also be regulated by miR-1, which is significantly down-regulated in hypertrophic tissue." circulation_biomarker_diagnosis_up hsa-mir-1-1 Coronary Artery Disease 17965831 "miR-1 is overexpressed in patients with coronary artery disease and that overexpression of miR-1 in a rat model of cardiac infarction exacerbated arrhythmogenesis. Cardiac hypertrophy may also be regulated by miR-1, which is significantly down-regulated in hypertrophic tissue." circulation_biomarker_diagnosis_up hsa-mir-1-2 "Cardiomyopathy, Hypertrophic" 17965831 "miR-1 is overexpressed in patients with coronary artery disease and that overexpression of miR-1 in a rat model of cardiac infarction exacerbated arrhythmogenesis. Cardiac hypertrophy may also be regulated by miR-1, which is significantly down-regulated in hypertrophic tissue." circulation_biomarker_diagnosis_up hsa-mir-1-2 Coronary Artery Disease 17965831 "miR-1 is overexpressed in patients with coronary artery disease and that overexpression of miR-1 in a rat model of cardiac infarction exacerbated arrhythmogenesis. Cardiac hypertrophy may also be regulated by miR-1, which is significantly down-regulated in hypertrophic tissue." circulation_biomarker_diagnosis_up hsa-mir-146a Psoriasis 17965831 miR-146 is also expressed highly in the skin of psoriasis patients. circulation_biomarker_diagnosis_up hsa-mir-146a Thyroid Neoplasms 17965831 "Numerous miRNAs are also up-regulated in papillary thyroid carcinoma, including miR-221, miR-22 and miR-146. This up-regulation was associated with a downregulation in the expression of the oncogene KIT, a tyrosine kinase important for the control of cell proliferation." circulation_biomarker_diagnosis_up hsa-mir-146b Psoriasis 17965831 miR-146 is also expressed highly in the skin of psoriasis patients. circulation_biomarker_diagnosis_up hsa-mir-146b Thyroid Neoplasms 17965831 "Numerous miRNAs are also up-regulated in papillary thyroid carcinoma, including miR-221, miR-22 and miR-146. This up-regulation was associated with a downregulation in the expression of the oncogene KIT, a tyrosine kinase important for the control of cell proliferation." circulation_biomarker_diagnosis_up hsa-mir-22 Thyroid Neoplasms 17965831 "Numerous miRNAs are also up-regulated in papillary thyroid carcinoma, including miR-221, miR-22 and miR-146. This up-regulation was associated with a downregulation in the expression of the oncogene KIT, a tyrosine kinase important for the control of cell proliferation." circulation_biomarker_diagnosis_up hsa-mir-221 Thyroid Neoplasms 17965831 "Numerous miRNAs are also up-regulated in papillary thyroid carcinoma, including miR-221, miR-22 and miR-146. This up-regulation was associated with a downregulation in the expression of the oncogene KIT, a tyrosine kinase important for the control of cell proliferation." circulation_biomarker_diagnosis_up hsa-mir-16-1 Polycythemia Vera 17976518 "Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11." circulation_biomarker_diagnosis_up hsa-mir-16-2 Polycythemia Vera 17976518 "Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11." circulation_biomarker_diagnosis_up hsa-mir-21 Polycythemia Vera 17976518 "Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11." circulation_biomarker_diagnosis_up hsa-mir-26b Polycythemia Vera 17976518 "Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11." circulation_biomarker_diagnosis_up hsa-mir-451a Polycythemia Vera 17976518 "Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11." circulation_biomarker_diagnosis_up hsa-mir-128a "Leukemia, Lymphoblastic" 18056805 "Among them, miR-128a and -128b are significantly overexpressed, whereas let-7b and miR-223 are significantly down-regulated in ALL compared with AML." circulation_biomarker_diagnosis_up hsa-mir-128b "Leukemia, Lymphoblastic" 18056805 "Among them, miR-128a and -128b are significantly overexpressed, whereas let-7b and miR-223 are significantly down-regulated in ALL compared with AML." circulation_biomarker_diagnosis_up hsa-mir-212 Liver Diseases [unspecific] 18162065 increased circulation_biomarker_diagnosis_up hsa-mir-21 "Carcinoma, Hepatocellular" 18223217 increased circulation_biomarker_diagnosis_up hsa-mir-128-2 Lung Neoplasms 18304967 increased circulation_biomarker_diagnosis_up hsa-mir-150 Lymphoma 18348159 "Three of 15 miRNAs (miR-16, miR-21, and miR-150) showed a high expression level in both blood and lymph node samples. " circulation_biomarker_diagnosis_up hsa-mir-16 Lymphoma 18348159 "Three of 15 miRNAs (miR-16, miR-21, and miR-150) showed a high expression level in both blood and lymph node samples. " circulation_biomarker_diagnosis_up hsa-mir-21 Lymphoma 18348159 "Three of 15 miRNAs (miR-16, miR-21, and miR-150) showed a high expression level in both blood and lymph node samples. " circulation_biomarker_diagnosis_up hsa-mir-146a Eczema Herpeticum 18419608 upregulation circulation_biomarker_diagnosis_up hsa-mir-143 Polycythemia Vera 18508790 "We observed down-regulation of let-7a and up-regulation of miR-182 in polycythemia vera granulocytes, up-regulation of miR-143, miR-145 and miR-223 in polycythemia vera mononuclear cells, up-regulation of miR-26b in polycythemia vera platelets, and down-regulation of miR-30b, miR-30c and miR-150 in polycythemia vera reticulocytes." circulation_biomarker_diagnosis_up hsa-mir-145 Polycythemia Vera 18508790 "We observed down-regulation of let-7a and up-regulation of miR-182 in polycythemia vera granulocytes, up-regulation of miR-143, miR-145 and miR-223 in polycythemia vera mononuclear cells, up-regulation of miR-26b in polycythemia vera platelets, and down-regulation of miR-30b, miR-30c and miR-150 in polycythemia vera reticulocytes." circulation_biomarker_diagnosis_up hsa-mir-182 Polycythemia Vera 18508790 "We observed down-regulation of let-7a and up-regulation of miR-182 in polycythemia vera granulocytes, up-regulation of miR-143, miR-145 and miR-223 in polycythemia vera mononuclear cells, up-regulation of miR-26b in polycythemia vera platelets, and down-regulation of miR-30b, miR-30c and miR-150 in polycythemia vera reticulocytes." circulation_biomarker_diagnosis_up hsa-mir-223 Polycythemia Vera 18508790 "We observed down-regulation of let-7a and up-regulation of miR-182 in polycythemia vera granulocytes, up-regulation of miR-143, miR-145 and miR-223 in polycythemia vera mononuclear cells, up-regulation of miR-26b in polycythemia vera platelets, and down-regulation of miR-30b, miR-30c and miR-150 in polycythemia vera reticulocytes." circulation_biomarker_diagnosis_up hsa-mir-26b Polycythemia Vera 18508790 "We observed down-regulation of let-7a and up-regulation of miR-182 in polycythemia vera granulocytes, up-regulation of miR-143, miR-145 and miR-223 in polycythemia vera mononuclear cells, up-regulation of miR-26b in polycythemia vera platelets, and down-regulation of miR-30b, miR-30c and miR-150 in polycythemia vera reticulocytes." circulation_biomarker_diagnosis_up hsa-let-7a-1 "Lymphoma, Hodgkin" 18583325 "let-7a: overexpressed, down-regulation of PRDM1/Blimp-1" circulation_biomarker_diagnosis_up hsa-let-7a-2 "Lymphoma, Hodgkin" 18583325 "let-7a: overexpressed, down-regulation of PRDM1/Blimp-1" circulation_biomarker_diagnosis_up hsa-let-7a-3 "Lymphoma, Hodgkin" 18583325 "let-7a: overexpressed, down-regulation of PRDM1/Blimp-1" circulation_biomarker_diagnosis_up hsa-mir-9-1 "Lymphoma, Hodgkin" 18583325 "miR-9: overexpressed, down-regulation of PRDM1/Blimp-1" circulation_biomarker_diagnosis_up hsa-mir-9-2 "Lymphoma, Hodgkin" 18583325 "miR-9: overexpressed, down-regulation of PRDM1/Blimp-1" circulation_biomarker_diagnosis_up hsa-mir-9-3 "Lymphoma, Hodgkin" 18583325 "miR-9: overexpressed, down-regulation of PRDM1/Blimp-1" circulation_biomarker_diagnosis_up hsa-mir-17 "Carcinoma, Hepatocellular" 18688024 miR-17: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype circulation_biomarker_diagnosis_up hsa-mir-18a "Carcinoma, Hepatocellular" 18688024 miR-18a: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype circulation_biomarker_diagnosis_up hsa-mir-19a "Carcinoma, Hepatocellular" 18688024 miR-19a: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype circulation_biomarker_diagnosis_up hsa-mir-19b-1 "Carcinoma, Hepatocellular" 18688024 miR-19b: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype circulation_biomarker_diagnosis_up hsa-mir-19b-2 "Carcinoma, Hepatocellular" 18688024 miR-19b: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype circulation_biomarker_diagnosis_up hsa-mir-20a "Carcinoma, Hepatocellular" 18688024 miR-20a: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype circulation_biomarker_diagnosis_up hsa-mir-21 "Carcinoma, Hepatocellular" 18688024 miR-21: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype circulation_biomarker_diagnosis_up hsa-mir-92a-1 "Carcinoma, Hepatocellular" 18688024 miR-92a: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype circulation_biomarker_diagnosis_up hsa-mir-92a-2 "Carcinoma, Hepatocellular" 18688024 miR-92a: Elevated expression of the miR-17-92 polycistron and miR-21 contributes to the malignant phenotype circulation_biomarker_diagnosis_up hsa-mir-377 Diabetic Nephropathy 18716028 miR-377: MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy circulation_biomarker_diagnosis_up hsa-mir-20a Breast Neoplasms 18777135 miR-20a: increased expression in c-Myc induced mouse mammary tumors circulation_biomarker_diagnosis_up hsa-mir-20b Breast Neoplasms 18777135 miR-20b: increased expression in c-Myc induced mouse mammary tumors circulation_biomarker_diagnosis_up hsa-mir-9-1 Breast Neoplasms 18777135 miR-9: increased expression in c-Myc induced mouse mammary tumors circulation_biomarker_diagnosis_up hsa-mir-9-2 Breast Neoplasms 18777135 miR-9: increased expression in c-Myc induced mouse mammary tumors circulation_biomarker_diagnosis_up hsa-mir-9-3 Breast Neoplasms 18777135 miR-9: increased expression in c-Myc induced mouse mammary tumors circulation_biomarker_diagnosis_up hsa-mir-206 Muscular Dystrophy 18827405 miR-206: miR-206 high expression for muscle regeneration and maturation circulation_biomarker_diagnosis_up hsa-mir-1-1 Retinal Degeneration 18834879 miR-1: upregulation circulation_biomarker_diagnosis_up hsa-mir-1-2 Retinal Degeneration 18834879 miR-1: upregulation circulation_biomarker_diagnosis_up hsa-mir-133b Retinal Degeneration 18834879 miR-133: upregulation circulation_biomarker_diagnosis_up hsa-mir-142 Retinal Degeneration 18834879 miR-142: upregulation circulation_biomarker_diagnosis_up hsa-mir-196b Leukemia 18923441 the expression of miR-196b was 500-fold higher in MLL-rearranged and 800-fold higher in 5 of 15 T-ALL cases as compared with the expression level in the remaining precursor B-ALL cases (P<0.001). circulation_biomarker_diagnosis_up hsa-let-7b Neurodegenerative Diseases [unspecific] 18987751 let-7b: up-regulated circulation_biomarker_diagnosis_up hsa-mir-139 Neurodegenerative Diseases [unspecific] 18987751 miR-139-5p: up-regulated circulation_biomarker_diagnosis_up hsa-mir-146a Neurodegenerative Diseases [unspecific] 18987751 miR-146a: up-regulated circulation_biomarker_diagnosis_up hsa-mir-328 Neurodegenerative Diseases [unspecific] 18987751 miR-328: up-regulated circulation_biomarker_diagnosis_up hsa-mir-342 Neurodegenerative Diseases [unspecific] 18987751 miR-342-3p: up-regulated circulation_biomarker_diagnosis_up hsa-let-7a-1 Lupus Vulgaris 18998140 let-7a: upregulation circulation_biomarker_diagnosis_up hsa-let-7a-2 Lupus Vulgaris 18998140 let-7a: upregulation circulation_biomarker_diagnosis_up hsa-let-7a-3 Lupus Vulgaris 18998140 let-7a: upregulation circulation_biomarker_diagnosis_up hsa-let-7e Lupus Vulgaris 18998140 let-7e: upregulation circulation_biomarker_diagnosis_up hsa-mir-130b Lupus Vulgaris 18998140 miR-130b: upregulation circulation_biomarker_diagnosis_up hsa-mir-134 Lupus Vulgaris 18998140 miR-134: upregulation circulation_biomarker_diagnosis_up hsa-mir-142 Lupus Vulgaris 18998140 miR-142-5p: upregulation circulation_biomarker_diagnosis_up hsa-mir-184 Lupus Vulgaris 18998140 miR-184: upregulation circulation_biomarker_diagnosis_up hsa-mir-185 Lupus Vulgaris 18998140 miR-185: upregulation circulation_biomarker_diagnosis_up hsa-mir-195 Lupus Vulgaris 18998140 miR-195: upregulation circulation_biomarker_diagnosis_up hsa-mir-197 Lupus Vulgaris 18998140 miR-197: upregulation circulation_biomarker_diagnosis_up hsa-mir-198 Lupus Vulgaris 18998140 miR-198: upregulation circulation_biomarker_diagnosis_up hsa-mir-200c Lupus Vulgaris 18998140 miR-200c: upregulation circulation_biomarker_diagnosis_up hsa-mir-208b Lupus Vulgaris 18998140 miR-208: upregulation circulation_biomarker_diagnosis_up hsa-mir-23a Lupus Vulgaris 18998140 miR-23a: upregulation circulation_biomarker_diagnosis_up hsa-mir-30a Lupus Vulgaris 18998140 miR-30a-5p: upregulation circulation_biomarker_diagnosis_up hsa-mir-433 Lupus Vulgaris 18998140 miR-433: upregulation circulation_biomarker_diagnosis_up hsa-mir-494 Lupus Vulgaris 18998140 miR-494: upregulation circulation_biomarker_diagnosis_up hsa-mir-516a-1 Lupus Vulgaris 18998140 miR-516-5p: upregulation circulation_biomarker_diagnosis_up hsa-mir-516a-2 Lupus Vulgaris 18998140 miR-516-5p: upregulation circulation_biomarker_diagnosis_up hsa-mir-516b-1 Lupus Vulgaris 18998140 miR-516-5p: upregulation circulation_biomarker_diagnosis_up hsa-mir-516b-2 Lupus Vulgaris 18998140 miR-516-5p: upregulation circulation_biomarker_diagnosis_up hsa-mir-518c Lupus Vulgaris 18998140 miR-518c*: upregulation circulation_biomarker_diagnosis_up hsa-mir-575 Lupus Vulgaris 18998140 miR-575: upregulation circulation_biomarker_diagnosis_up hsa-mir-583 Lupus Vulgaris 18998140 miR-583: upregulation circulation_biomarker_diagnosis_up hsa-mir-600 Lupus Vulgaris 18998140 miR-600: upregulation circulation_biomarker_diagnosis_up hsa-mir-601 Lupus Vulgaris 18998140 miR-601: upregulation circulation_biomarker_diagnosis_up hsa-mir-608 Lupus Vulgaris 18998140 miR-608: upregulation circulation_biomarker_diagnosis_up hsa-mir-612 Lupus Vulgaris 18998140 miR-612: upregulation circulation_biomarker_diagnosis_up hsa-mir-622 Lupus Vulgaris 18998140 miR-622: upregulation circulation_biomarker_diagnosis_up hsa-mir-638 Lupus Vulgaris 18998140 miR-638: upregulation circulation_biomarker_diagnosis_up hsa-mir-657 Lupus Vulgaris 18998140 miR-657: upregulation circulation_biomarker_diagnosis_up hsa-mir-658 Lupus Vulgaris 18998140 miR-658: upregulation circulation_biomarker_diagnosis_up hsa-mir-662 Lupus Vulgaris 18998140 miR-662: upregulation circulation_biomarker_diagnosis_up hsa-mir-125a Leukemia 19022373 miR-125a: upregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal circulation_biomarker_diagnosis_up hsa-mir-339 Leukemia 19022373 miR-339: upregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal circulation_biomarker_diagnosis_up hsa-mir-660 Leukemia 19022373 miR-660: upregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal circulation_biomarker_diagnosis_up hsa-mir-663a Leukemia 19022373 miR-663: upregulated during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal circulation_biomarker_diagnosis_up hsa-mir-145 Colorectal Carcinoma 19047896 miR-145: increased expression circulation_biomarker_diagnosis_up hsa-mir-181b-1 Colorectal Carcinoma 19047896 miR-181b: increased expression circulation_biomarker_diagnosis_up hsa-mir-203 Colorectal Carcinoma 19047896 miR-203: increased expression circulation_biomarker_diagnosis_up hsa-mir-20a Colorectal Carcinoma 19047896 miR-20a: increased expression circulation_biomarker_diagnosis_up hsa-mir-21 Colorectal Carcinoma 19047896 miR-21: increased expression circulation_biomarker_diagnosis_up hsa-mir-372 "Carcinoma, Embryonal" 19057917 miR-372: highly up-regulated circulation_biomarker_diagnosis_up hsa-mir-372 Cerebellum Cancer 19057917 miR-372: highly up-regulated circulation_biomarker_diagnosis_up hsa-mir-373 "Carcinoma, Embryonal" 19057917 miR-373: highly up-regulated circulation_biomarker_diagnosis_up hsa-mir-373 Cerebellum Cancer 19057917 miR-373: highly up-regulated circulation_biomarker_diagnosis_up hsa-mir-17 "Leukemia, Myeloid" 19155294 miR-17: overexpressed circulation_biomarker_diagnosis_up hsa-mir-18a "Leukemia, Myeloid" 19155294 miR-18a: overexpressed circulation_biomarker_diagnosis_up hsa-mir-19a "Leukemia, Myeloid" 19155294 miR-19a: overexpressed circulation_biomarker_diagnosis_up hsa-mir-19b-1 "Leukemia, Myeloid" 19155294 miR-19b: overexpressed circulation_biomarker_diagnosis_up hsa-mir-19b-2 "Leukemia, Myeloid" 19155294 miR-19b: overexpressed circulation_biomarker_diagnosis_up hsa-mir-20a "Leukemia, Myeloid" 19155294 miR-20a: overexpressed circulation_biomarker_diagnosis_up hsa-mir-92a-1 "Leukemia, Myeloid" 19155294 miR-92a: overexpressed circulation_biomarker_diagnosis_up hsa-mir-92a-2 "Leukemia, Myeloid" 19155294 miR-92a: overexpressed circulation_biomarker_diagnosis_up hsa-mir-155 "Lymphoma, Hodgkin" 19177201 miR-155: overexpressed circulation_biomarker_diagnosis_up hsa-mir-16-1 "Lymphoma, Hodgkin" 19177201 miR-16: overexpressed circulation_biomarker_diagnosis_up hsa-mir-16-2 "Lymphoma, Hodgkin" 19177201 miR-16: overexpressed circulation_biomarker_diagnosis_up hsa-mir-17 "Lymphoma, Hodgkin" 19177201 miR-17: overexpressed circulation_biomarker_diagnosis_up hsa-mir-18a "Lymphoma, Hodgkin" 19177201 miR-18a: overexpressed circulation_biomarker_diagnosis_up hsa-mir-19a "Lymphoma, Hodgkin" 19177201 miR-19a: overexpressed circulation_biomarker_diagnosis_up hsa-mir-19b-1 "Lymphoma, Hodgkin" 19177201 miR-19b: overexpressed circulation_biomarker_diagnosis_up hsa-mir-19b-2 "Lymphoma, Hodgkin" 19177201 miR-19b: overexpressed circulation_biomarker_diagnosis_up hsa-mir-20a "Lymphoma, Hodgkin" 19177201 miR-20a: overexpressed circulation_biomarker_diagnosis_up hsa-mir-21 "Lymphoma, Hodgkin" 19177201 miR-21: overexpressed circulation_biomarker_diagnosis_up hsa-mir-24-1 "Lymphoma, Hodgkin" 19177201 miR-24: overexpressed circulation_biomarker_diagnosis_up hsa-mir-24-2 "Lymphoma, Hodgkin" 19177201 miR-24: overexpressed circulation_biomarker_diagnosis_up hsa-mir-92a-1 "Lymphoma, Hodgkin" 19177201 miR-92a: overexpressed circulation_biomarker_diagnosis_up hsa-mir-92a-2 "Lymphoma, Hodgkin" 19177201 miR-92a: overexpressed circulation_biomarker_diagnosis_up hsa-mir-142 "Leukemia-Lymphoma, Precursor B-Cell Lymphoblastic" 19206004 miR-142-3p: up-regulated circulation_biomarker_diagnosis_up hsa-mir-222 "Leukemia-Lymphoma, Precursor B-Cell Lymphoblastic" 19206004 miR-222: up-regulated circulation_biomarker_diagnosis_up hsa-mir-339 "Leukemia-Lymphoma, Precursor B-Cell Lymphoblastic" 19206004 miR-339: up-regulated circulation_biomarker_diagnosis_up hsa-mir-184 Tongue Neoplasms 19219377 miR-184: overexpressed circulation_biomarker_diagnosis_up hsa-mir-31 Colorectal Carcinoma 19242066 miR-31: up-regulated compared with normal control circulation_biomarker_diagnosis_up hsa-mir-1-1 Myocardial Infarction 19245789 miR-1: Upregulated expression in a rat model circulation_biomarker_diagnosis_up hsa-mir-1-2 Myocardial Infarction 19245789 miR-1: Upregulated expression in a rat model circulation_biomarker_diagnosis_up hsa-mir-206 Myocardial Infarction 19245789 miR-206: Upregulated expression in a rat model circulation_biomarker_diagnosis_up hsa-mir-132 Autistic Disorder 19360674 miR-132: upregulated circulation_biomarker_diagnosis_up hsa-mir-146a Autistic Disorder 19360674 miR-146a: upregulated circulation_biomarker_diagnosis_up hsa-mir-146b Autistic Disorder 19360674 mir-146b: upregulated circulation_biomarker_diagnosis_up hsa-mir-23a Autistic Disorder 19360674 miR-23a: upregulated circulation_biomarker_diagnosis_up hsa-mir-23b Autistic Disorder 19360674 miR-23b: upregulated circulation_biomarker_diagnosis_up hsa-mir-663a Autistic Disorder 19360674 miR-663: upregulated circulation_biomarker_diagnosis_up hsa-mir-342 Prion Diseases 19712440 upregulated circulation_biomarker_diagnosis_up hsa-mir-494 Prion Diseases 19712440 upregulated circulation_biomarker_diagnosis_up hsa-mir-181a-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 high expression circulation_biomarker_diagnosis_up hsa-mir-15a Schizophrenia 19721432 upregulated circulation_biomarker_diagnosis_up hsa-mir-15b Schizophrenia 19721432 upregulated circulation_biomarker_diagnosis_up hsa-mir-196a-1 Pancreatic Adenocarcinoma 19723895 uperegulated circulation_biomarker_diagnosis_up hsa-mir-196a-2 Pancreatic Adenocarcinoma 19723895 uperegulated circulation_biomarker_diagnosis_up hsa-mir-122 Stroke 19745058 diagnostical sensitivity: illustrated liver and muscle toxicity circulation_biomarker_diagnosis_up hsa-mir-124-1 Stroke 19745058 "diagnostical sensitivity:illustrated injuries in liver, muscle, and brain" circulation_biomarker_diagnosis_up hsa-mir-124-2 Stroke 19745058 "diagnostical sensitivity:illustrated injuries in liver, muscle, and brain" circulation_biomarker_diagnosis_up hsa-mir-124-3 Stroke 19745058 "diagnostical sensitivity:illustrated injuries in liver, muscle, and brain" circulation_biomarker_diagnosis_up hsa-mir-133a-1 Stroke 19745058 diagnostical sensitivity: illustrated liver and muscle toxicity circulation_biomarker_diagnosis_up hsa-mir-133a-2 Stroke 19745058 diagnostical sensitivity: illustrated liver and muscle toxicity circulation_biomarker_diagnosis_up hsa-mir-208a Myocardial Infarction 20159880 Elevated cardiac-specific miR-208a in plasma may be a novel biomarker for early detection of myocardial injury in humans circulation_biomarker_diagnosis_up hsa-mir-423 Heart Failure 20185794 MiR423-5p as a circulating biomarker for heart failure circulation_biomarker_diagnosis_up hsa-mir-210 "Squamous Cell Carcinoma, Head and Neck" 20187102 Expression of hsa-miR-210 in head and neck cancer correlates with other approaches for assessing hypoxia and is associated with prognosis circulation_biomarker_diagnosis_up hsa-mir-106a Neoplasms [unspecific] 20234369 "the plasma concentrations of miRNAs (miR-17-5p, miR-21, miR-106a, miR-106b) were significantly higher in GC patients than controls" circulation_biomarker_diagnosis_up hsa-mir-17 Neoplasms [unspecific] 20234369 "the plasma concentrations of miRNAs (miR-17-5p, miR-21, miR-106a, miR-106b) were significantly higher in GC patients than controls" circulation_biomarker_diagnosis_up hsa-mir-21 Neoplasms [unspecific] 20234369 "the plasma concentrations of miRNAs (miR-17-5p, miR-21, miR-106a, miR-106b) were significantly higher in GC patients than controls" circulation_biomarker_diagnosis_up hsa-mir-210 Pancreatic Neoplasms 20360935 Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer circulation_biomarker_diagnosis_up hsa-mir-23a "Child Development Disorders, Pervasive" 20374639 up-regulation circulation_biomarker_diagnosis_up hsa-mir-21 "Leukemia, Lymphocytic, Chronic, B-Cell" 20393129 microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival circulation_biomarker_diagnosis_up hsa-mir-499a Myocardial Infarction 20395621 Plasma microRNA 499 as a biomarker of acute myocardial infarction circulation_biomarker_diagnosis_up hsa-mir-223 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 20418243 miR-223:over-expression of miR-223 circulation_biomarker_diagnosis_up hsa-mir-126 Atherosclerosis 20489169 miR-126:found high levels of expression for all of them in quiescent endothelial cells circulation_biomarker_diagnosis_up hsa-mir-17 Atherosclerosis 20489169 miR-17-5p:found high levels of expression for all of them in quiescent endothelial cells circulation_biomarker_diagnosis_up hsa-mir-21 Atherosclerosis 20489169 miR-21:found high levels of expression for all of them in quiescent endothelial cells circulation_biomarker_diagnosis_up hsa-mir-210 Atherosclerosis 20489169 miR-210:found high levels of expression for all of them in quiescent endothelial cells circulation_biomarker_diagnosis_up hsa-mir-221 Atherosclerosis 20489169 miR-221:found high levels of expression for all of them in quiescent endothelial cells circulation_biomarker_diagnosis_up hsa-mir-222 Atherosclerosis 20489169 miR-222:found high levels of expression for all of them in quiescent endothelial cells circulation_biomarker_diagnosis_up hsa-mir-296 Atherosclerosis 20489169 miR-296:found high levels of expression for all of them in quiescent endothelial cells circulation_biomarker_diagnosis_up hsa-mir-148a "Leukemia, Lymphocytic, Chronic, B-Cell" 20504344 "miR-148a:miR-148a, miR-222 and miR-21 exhibited a significantly higher expression in non-responder patients" circulation_biomarker_diagnosis_up hsa-mir-21 "Leukemia, Lymphocytic, Chronic, B-Cell" 20504344 "miR-21:miR-148a, miR-222 and miR-21 exhibited a significantly higher expression in non-responder patients" circulation_biomarker_diagnosis_up hsa-mir-222 "Leukemia, Lymphocytic, Chronic, B-Cell" 20504344 "miR-222:miR-148a, miR-222 and miR-21 exhibited a significantly higher expression in non-responder patients" circulation_biomarker_diagnosis_up hsa-let-7d Melanoma 20529253 let-7d:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-1249 Melanoma 20529253 miR-1249:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-125a Melanoma 20529253 miR-125a-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-1280 Melanoma 20529253 miR-1280:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-142 Melanoma 20529253 miR-142-3p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-145 Melanoma 20529253 miR-145:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-146a Melanoma 20529253 miR-146a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-151a Melanoma 20529253 miR-151-3p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-181a-2 Melanoma 20529253 miR-181a-2*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-183 Melanoma 20529253 miR-183*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-186 Melanoma 20529253 miR-186:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-18a Melanoma 20529253 miR-18a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-199a-1 Melanoma 20529253 miR-199a-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-199a-2 Melanoma 20529253 miR-199a-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-22 Melanoma 20529253 miR-22*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-30a Melanoma 20529253 miR-30a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-30e Melanoma 20529253 miR-30e*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-328 Melanoma 20529253 miR-328:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-342 Melanoma 20529253 miR-342-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-361 Melanoma 20529253 miR-361-3p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-362 Melanoma 20529253 miR-362-3p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-365a Melanoma 20529253 miR-365:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-365b Melanoma 20529253 miR-365:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-378a Melanoma 20529253 miR-378*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-422a Melanoma 20529253 miR-422a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-501 Melanoma 20529253 miR-501-5p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-550a-1 Melanoma 20529253 miR-550*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-550a-2 Melanoma 20529253 miR-550*:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-584 Melanoma 20529253 miR-584:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-625 Melanoma 20529253 miR-625:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-664 Melanoma 20529253 miR-664:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-99a Melanoma 20529253 miR-99a:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients circulation_biomarker_diagnosis_up hsa-mir-125b-1 "Leukemia, Myeloid" 20660734 "miR-125b:Overexpression of the most advantageous miRNA, miR-125b, caused a dose-dependent myeloproliferative disorder that progressed to a lethal myeloid leukemia in mice" circulation_biomarker_diagnosis_up hsa-mir-125b-2 "Leukemia, Myeloid" 20660734 "miR-125b:Overexpression of the most advantageous miRNA, miR-125b, caused a dose-dependent myeloproliferative disorder that progressed to a lethal myeloid leukemia in mice" circulation_biomarker_diagnosis_up hsa-mir-206 Rhabdomyosarcoma 20696132 "miR-206:miR-206, as landmark biomarkers for RMS" circulation_biomarker_diagnosis_up hsa-mir-155 "Lymphoma, Large-Cell, Anaplastic" 20805506 "miR-155:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL" circulation_biomarker_diagnosis_up hsa-mir-17 "Lymphoma, Large-Cell, Anaplastic" 20805506 "miR-17:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL" circulation_biomarker_diagnosis_up hsa-mir-18a "Lymphoma, Large-Cell, Anaplastic" 20805506 "miR-18a:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL" circulation_biomarker_diagnosis_up hsa-mir-19a "Lymphoma, Large-Cell, Anaplastic" 20805506 "miR-19a:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL" circulation_biomarker_diagnosis_up hsa-mir-19b-1 "Lymphoma, Large-Cell, Anaplastic" 20805506 "miR-19b:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL" circulation_biomarker_diagnosis_up hsa-mir-19b-2 "Lymphoma, Large-Cell, Anaplastic" 20805506 "miR-19b:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL" circulation_biomarker_diagnosis_up hsa-mir-20a "Lymphoma, Large-Cell, Anaplastic" 20805506 "miR-20a:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL" circulation_biomarker_diagnosis_up hsa-mir-92a-1 "Lymphoma, Large-Cell, Anaplastic" 20805506 "miR-92a:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL" circulation_biomarker_diagnosis_up hsa-mir-92a-2 "Lymphoma, Large-Cell, Anaplastic" 20805506 "miR-92a:Five members of the miR-17-92 cluster were expressed more highly in ALK(+) ALCL, whereas miR-155 was expressed more than 10-fold higher in ALK(-) ALCL" circulation_biomarker_diagnosis_up hsa-mir-208b Myocardial Infarction 20921333 miRs-208b and -499 were highly elevated in acute myocardial infarction plasma circulation_biomarker_diagnosis_up hsa-mir-208b Viral Myocarditis 20921333 a milder but significant elevation of miRs-208b and -499 were highly elevated in Viral Myocarditis plasma circulation_biomarker_diagnosis_up hsa-mir-499a Heart Failure 20921333 miR-499 was significantly elevated circulation_biomarker_diagnosis_up hsa-mir-499a Myocardial Infarction 20921333 miRs-208b and -499 were highly elevated in acute myocardial infarction plasma circulation_biomarker_diagnosis_up hsa-mir-499a Viral Myocarditis 20921333 a milder but significant elevation of miRs-208b and -499 were highly elevated in Viral Myocarditis plasma circulation_biomarker_diagnosis_up hsa-let-7e Synovial Sarcoma 21140508 upregulated circulation_biomarker_diagnosis_up hsa-mir-125a Synovial Sarcoma 21140508 miR-125a-3p: upregulated circulation_biomarker_diagnosis_up hsa-mir-99b Synovial Sarcoma 21140508 upregulated circulation_biomarker_diagnosis_up hsa-mir-326 Multiple Sclerosis 21151203 The expression of miRNA-326 in blood cells has been reported to increase during relapses. circulation_biomarker_diagnosis_up hsa-mir-122 Liver Neoplasms 21154767 "in serum, miR-21, miR-122, and miR-223 were significantly higher in patients with HCC than those in healthy controls" circulation_biomarker_diagnosis_up hsa-mir-223 Liver Neoplasms 21154767 "in serum, miR-21, miR-122, and miR-223 were significantly higher in patients with HCC than those in healthy controls" circulation_biomarker_diagnosis_up hsa-mir-183 Urinary Bladder Cancer 21166959 "MiR-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma: correlation with stage and grade, and comparison with urinary cytology." circulation_biomarker_diagnosis_up hsa-mir-96 Urinary Bladder Cancer 21166959 "MiR-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma: correlation with stage and grade, and comparison with urinary cytology." circulation_biomarker_diagnosis_up hsa-mir-122 "Carcinoma, Hepatocellular" 21229610 "Our results indicate that serum miR-21, miR-122 and miR-223 are elevated in patients with HCC or chronic hepatitis and these miRNAs have strong potential to serve as novel biomarkers for liver injury but not specifically for HCC." circulation_biomarker_diagnosis_up hsa-mir-21 "Carcinoma, Hepatocellular" 21229610 "Our results indicate that serum miR-21, miR-122 and miR-223 are elevated in patients with HCC or chronic hepatitis and these miRNAs have strong potential to serve as novel biomarkers for liver injury but not specifically for HCC." circulation_biomarker_diagnosis_up hsa-mir-223 "Carcinoma, Hepatocellular" 21229610 "Our results indicate that serum miR-21, miR-122 and miR-223 are elevated in patients with HCC or chronic hepatitis and these miRNAs have strong potential to serve as novel biomarkers for liver injury but not specifically for HCC." circulation_biomarker_diagnosis_up hsa-mir-100 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 21242186 "aberrant downregulation of let-7b (~70-fold) in MLL-rearranged acute lymphoblastic leukemia was linked to upregulation of oncoprotein c-Myc (P<0.0001). Resistance to vincristine and daunorubicin was characterized by ~20-fold upregulation of miR-125b, miR-99a and miR-100 (P<0.002)." circulation_biomarker_diagnosis_up hsa-mir-125b-1 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 21242186 "aberrant downregulation of let-7b (~70-fold) in MLL-rearranged acute lymphoblastic leukemia was linked to upregulation of oncoprotein c-Myc (P<0.0001). Resistance to vincristine and daunorubicin was characterized by ~20-fold upregulation of miR-125b, miR-99a and miR-100 (P<0.002)." circulation_biomarker_diagnosis_up hsa-mir-125b-2 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 21242186 "aberrant downregulation of let-7b (~70-fold) in MLL-rearranged acute lymphoblastic leukemia was linked to upregulation of oncoprotein c-Myc (P<0.0001). Resistance to vincristine and daunorubicin was characterized by ~20-fold upregulation of miR-125b, miR-99a and miR-100 (P<0.002)." circulation_biomarker_diagnosis_up hsa-mir-99a "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 21242186 "aberrant downregulation of let-7b (~70-fold) in MLL-rearranged acute lymphoblastic leukemia was linked to upregulation of oncoprotein c-Myc (P<0.0001). Resistance to vincristine and daunorubicin was characterized by ~20-fold upregulation of miR-125b, miR-99a and miR-100 (P<0.002)." circulation_biomarker_diagnosis_up hsa-mir-181a-1 "Squamous Cell Carcinoma, Oral" 21244495 "miR-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma.miR-181 may enhance lymph-node metastasis through regulating migration, which could potentially be exploited as a putative biomarker for patients with OSCC." circulation_biomarker_diagnosis_up hsa-mir-181a-2 "Squamous Cell Carcinoma, Oral" 21244495 "miR-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma.miR-181 may enhance lymph-node metastasis through regulating migration, which could potentially be exploited as a putative biomarker for patients with OSCC." circulation_biomarker_diagnosis_up hsa-mir-181b-1 "Squamous Cell Carcinoma, Oral" 21244495 "miR-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma.miR-181 may enhance lymph-node metastasis through regulating migration, which could potentially be exploited as a putative biomarker for patients with OSCC." circulation_biomarker_diagnosis_up hsa-mir-181b-2 "Squamous Cell Carcinoma, Oral" 21244495 "miR-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma.miR-181 may enhance lymph-node metastasis through regulating migration, which could potentially be exploited as a putative biomarker for patients with OSCC." circulation_biomarker_diagnosis_up hsa-mir-181c "Squamous Cell Carcinoma, Oral" 21244495 "miR-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma.miR-181 may enhance lymph-node metastasis through regulating migration, which could potentially be exploited as a putative biomarker for patients with OSCC." circulation_biomarker_diagnosis_up hsa-mir-181d "Squamous Cell Carcinoma, Oral" 21244495 "miR-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma.miR-181 may enhance lymph-node metastasis through regulating migration, which could potentially be exploited as a putative biomarker for patients with OSCC." circulation_biomarker_diagnosis_up hsa-mir-1254-1 "Carcinoma, Lung, Non-Small-Cell" 21258252 miR-1254 and miR-574-5p: Serum-Based microRNA Biomarkers for Early-Stage Non-small Cell Lung Cancer. The expression of hsa-miR-1254 and hsa-miR-574-5p was significantly increased in the early-stage NSCLC samples with respect to the controls. The utility of miR-1254 and miR-574-5p serum-based biomarkers as minimally invasive screening and triage tools for subsequent diagnostic evaluation warrants additional validation. circulation_biomarker_diagnosis_up hsa-mir-574 "Carcinoma, Lung, Non-Small-Cell" 21258252 miR-1254 and miR-574-5p: Serum-Based microRNA Biomarkers for Early-Stage Non-small Cell Lung Cancer. The expression of hsa-miR-1254 and hsa-miR-574-5p was significantly increased in the early-stage NSCLC samples with respect to the controls. The utility of miR-1254 and miR-574-5p serum-based biomarkers as minimally invasive screening and triage tools for subsequent diagnostic evaluation warrants additional validation. circulation_biomarker_diagnosis_up hsa-mir-221 Melanoma 21273047 Malignant melanoma patients had significantly higher miR-221 levels than healthy controls in serum. circulation_biomarker_diagnosis_up hsa-mir-141 Prostate Neoplasms 21274675 the miRNA levels in patient blood were higher than that of the controls circulation_biomarker_diagnosis_up hsa-mir-21 Prostate Neoplasms 21274675 the miRNA levels in patient blood were higher than that of the controls circulation_biomarker_diagnosis_up hsa-mir-221 Prostate Neoplasms 21274675 the miRNA levels in patient blood were higher than that of the controls circulation_biomarker_diagnosis_up hsa-mir-21 Hypertrophy 21303526 "The downregulation of miR-1, miR-133a, and upregulation of miR-21 can be reversed by one single upstream regulator, SRF." circulation_biomarker_diagnosis_up hsa-mir-148a Medulloblastoma 21358093 "A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas." circulation_biomarker_diagnosis_up hsa-mir-182 Medulloblastoma 21358093 "A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas." circulation_biomarker_diagnosis_up hsa-mir-183 Medulloblastoma 21358093 "A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas." circulation_biomarker_diagnosis_up hsa-mir-193a Medulloblastoma 21358093 "A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas." circulation_biomarker_diagnosis_up hsa-mir-193b Medulloblastoma 21358093 "A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas." circulation_biomarker_diagnosis_up hsa-mir-224 Medulloblastoma 21358093 "A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas." circulation_biomarker_diagnosis_up hsa-mir-452 Medulloblastoma 21358093 "A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas." circulation_biomarker_diagnosis_up hsa-mir-96 Medulloblastoma 21358093 "A number of miRNAs like miR-193a, miR-224/miR-452 cluster, miR-182/miR-183/miR-96 cluster, and miR-148a having potential tumor/metastasis suppressive activity were found to be overexpressed in the WNT signaling associated medulloblastomas." circulation_biomarker_diagnosis_up hsa-mir-210 Ischemic Diseases [unspecific] 21360638 "High levels of miR-210 have been linked to an in vivo hypoxic signature and associated with adverse prognosis in cancer patients. A wide spectrum of miR-210 targets have been identified, with roles in mitochondrial metabolism, angiogenesis, DNA repair, and cell survival." circulation_biomarker_diagnosis_up hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 21408091 upregulation circulation_biomarker_diagnosis_up hsa-mir-342 "Leukemia, Lymphocytic, Chronic, B-Cell" 21408091 miR-342-3p upregulation circulation_biomarker_diagnosis_up hsa-mir-34a "Leukemia, Lymphocytic, Chronic, B-Cell" 21408091 upregulation circulation_biomarker_diagnosis_up hsa-mir-34b Huntington Disease 21421997 Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease. circulation_biomarker_diagnosis_up hsa-mir-1-1 "Muscular Dystrophy, Duchenne" 21479190 "the serum levels of several muscle-specific miRNAs (miR-1, miR-133a and miR-206) are increased" circulation_biomarker_diagnosis_up hsa-mir-1-2 "Muscular Dystrophy, Duchenne" 21479190 "the serum levels of several muscle-specific miRNAs (miR-1, miR-133a and miR-206) are increased" circulation_biomarker_diagnosis_up hsa-mir-133a-1 "Muscular Dystrophy, Duchenne" 21479190 "the serum levels of several muscle-specific miRNAs (miR-1, miR-133a and miR-206) are increased" circulation_biomarker_diagnosis_up hsa-mir-133a-2 "Muscular Dystrophy, Duchenne" 21479190 "the serum levels of several muscle-specific miRNAs (miR-1, miR-133a and miR-206) are increased" circulation_biomarker_diagnosis_up hsa-mir-206 "Muscular Dystrophy, Duchenne" 21479190 "the serum levels of several muscle-specific miRNAs (miR-1, miR-133a and miR-206) are increased" circulation_biomarker_diagnosis_up hsa-mir-146a Systemic Lupus Erythematosus 21529448 Increased Expression in Peripheral Blood Mononuclear Cells in Patients with Systemic Lupus Erythematosus. circulation_biomarker_diagnosis_up hsa-mir-9-1 Wounds and Injuries [unspecific] 21538484 Upregulated in in serum circulation_biomarker_diagnosis_up hsa-mir-9-2 Wounds and Injuries [unspecific] 21538484 Upregulated in in serum circulation_biomarker_diagnosis_up hsa-mir-9-3 Wounds and Injuries [unspecific] 21538484 Upregulated in in serum circulation_biomarker_diagnosis_up hsa-mir-29c "Carcinoma, Lung, Non-Small-Cell" 21544802 "The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased." circulation_biomarker_diagnosis_up hsa-mir-124-1 Acute Cerebral Infarction 21551949 "Plasma concentrations of miR-124 were significantly elevated at 6 h, and remained elevated at 48 h after middle cerebral artery occlusion introduction." circulation_biomarker_diagnosis_up hsa-mir-124-2 Acute Cerebral Infarction 21551949 "Plasma concentrations of miR-124 were significantly elevated at 6 h, and remained elevated at 48 h after middle cerebral artery occlusion introduction." circulation_biomarker_diagnosis_up hsa-mir-124-3 Acute Cerebral Infarction 21551949 "Plasma concentrations of miR-124 were significantly elevated at 6 h, and remained elevated at 48 h after middle cerebral artery occlusion introduction." circulation_biomarker_diagnosis_up hsa-mir-128-1 Glioblastoma 21561454 upregulated in the peripheral blood of glioblastoma patients. circulation_biomarker_diagnosis_up hsa-mir-128-2 Glioblastoma 21561454 upregulated in the peripheral blood of glioblastoma patients. circulation_biomarker_diagnosis_up hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 21627863 "Plasma miR-21 was significantly higher in NSCLC patients than in age- and sex-matched controls (P < 0.001). miR-21 was related to TNM stage (P < 0.001), but not related to age, sex, smoking status, histological classification, lymph node status, and metastasis (all P > 0.05)." circulation_biomarker_diagnosis_up hsa-mir-1-1 Myocardial Infarction 21642241 Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage. circulation_biomarker_diagnosis_up hsa-mir-1-2 Myocardial Infarction 21642241 Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage. circulation_biomarker_diagnosis_up hsa-mir-133a-1 Myocardial Infarction 21642241 Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage. circulation_biomarker_diagnosis_up hsa-mir-133a-2 Myocardial Infarction 21642241 Increased MicroRNA-1 and MicroRNA-133a Levels in Serum of Patients With Cardiovascular Disease Indicate Myocardial Damage. circulation_biomarker_diagnosis_up hsa-mir-21 Myelodysplastic Syndromes 21649547 up-regulation circulation_biomarker_diagnosis_up hsa-mir-720 Myelodysplastic Syndromes 21649547 up-regulation circulation_biomarker_diagnosis_up hsa-mir-21 "Squamous Cell Carcinoma, Esophageal" 21673684 "the plasma level of miR-21 was significantly higher (P=0.0218) and that of miR-375 (P=0.0052) was significantly lower in ESCC patients than controls. (2) The high plasma miR-21 levels reflected tumour levels in all cases (100%). The plasma level of miR-21 was significantly reduced in postoperative samples (P=0.0058). (3) On validation analysis, the plasma level of miR-21 tended to be higher in ESCC patients (P=0.0649), while that of miR-375 was significantly lower (P<0.0001) and the miR-21/miR-375 ratio was significantly higher (P<0.0001) in ESCC patients than in controls. The value of the area under the receiver-operating characteristic curve (AUC) was 0.816 for the miR-21/miR-375 ratio assay. Patients with a high plasma level of miR-21 tended to have greater vascular invasion (P=0.1554) and to show a high correlation with recurrence (P=0.0164)." circulation_biomarker_diagnosis_up hsa-mir-146a Glomerulonephritis 21694443 The expression levels of miR-146a and miR-155 in kidney biopsy and urine from patients with IgA nephropathy were elevated. circulation_biomarker_diagnosis_up hsa-mir-155 Glomerulonephritis 21694443 The expression levels of miR-146a and miR-155 in kidney biopsy and urine from patients with IgA nephropathy were elevated. circulation_biomarker_diagnosis_up hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 21721011 serum miR-21 expression was an independent prognostic factor for NSCLC patients. circulation_biomarker_diagnosis_up hsa-mir-10a "Leukemia, Myeloid, Acute" 21784052 miR-10a overexpression is associated with NPM1 mutations and MDM4 downregulation in intermediate-risk acute myeloid leukemia. circulation_biomarker_diagnosis_up hsa-mir-196a-1 "Leukemia, Myeloid, Acute" 21818844 "High miR-196a and -b expression was observed in patients carrying MLL gene rearrangements, NPM1 mutations, or FLT3-ITD in a cytogenetically normal background, compared to all other patients. In contrast, CEBPA mutated cases had a low expression of miR-196a and -b. Expression of miR-196a and -b was correlated with expression of neighboring HOXA and HOXB genes." circulation_biomarker_diagnosis_up hsa-mir-196a-2 "Leukemia, Myeloid, Acute" 21818844 "High miR-196a and -b expression was observed in patients carrying MLL gene rearrangements, NPM1 mutations, or FLT3-ITD in a cytogenetically normal background, compared to all other patients. In contrast, CEBPA mutated cases had a low expression of miR-196a and -b. Expression of miR-196a and -b was correlated with expression of neighboring HOXA and HOXB genes." circulation_biomarker_diagnosis_up hsa-mir-196b "Leukemia, Myeloid, Acute" 21818844 "High miR-196a and -b expression was observed in patients carrying MLL gene rearrangements, NPM1 mutations, or FLT3-ITD in a cytogenetically normal background, compared to all other patients. In contrast, CEBPA mutated cases had a low expression of miR-196a and -b. Expression of miR-196a and -b was correlated with expression of neighboring HOXA and HOXB genes." circulation_biomarker_diagnosis_up hsa-mir-146a Atherosclerosis 21820659 "miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques (compared to non-atherosclerotic left internal thoracic arteries (LITA)) in the Tampere Vascular Study." circulation_biomarker_diagnosis_up hsa-mir-146b Atherosclerosis 21820659 "miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques (compared to non-atherosclerotic left internal thoracic arteries (LITA)) in the Tampere Vascular Study." circulation_biomarker_diagnosis_up hsa-mir-21 Atherosclerosis 21820659 "miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques (compared to non-atherosclerotic left internal thoracic arteries (LITA)) in the Tampere Vascular Study." circulation_biomarker_diagnosis_up hsa-mir-210 Atherosclerosis 21820659 "miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques (compared to non-atherosclerotic left internal thoracic arteries (LITA)) in the Tampere Vascular Study." circulation_biomarker_diagnosis_up hsa-mir-34a Atherosclerosis 21820659 "miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques (compared to non-atherosclerotic left internal thoracic arteries (LITA)) in the Tampere Vascular Study." circulation_biomarker_diagnosis_up hsa-mir-146a Multiple Sclerosis 21875645 "In peripheral mononuclear cells, a statistically significant increased expression of miR-21, miR-146a and -b was observed in relapsing remitting (RR)MS patients as compared with controls." circulation_biomarker_diagnosis_up hsa-mir-146b Multiple Sclerosis 21875645 "In peripheral mononuclear cells, a statistically significant increased expression of miR-21, miR-146a and -b was observed in relapsing remitting (RR)MS patients as compared with controls." circulation_biomarker_diagnosis_up hsa-mir-21 Multiple Sclerosis 21875645 "In peripheral mononuclear cells, a statistically significant increased expression of miR-21, miR-146a and -b was observed in relapsing remitting (RR)MS patients as compared with controls." circulation_biomarker_diagnosis_up hsa-mir-133a-1 Myocardial Infarction 21881276 "The miR-133 levels in plasma from AMI patients exhibited a 4.4-fold increase compared with control subjects (p=0.006). Moreover, the increased miR-133 levels in whole blood were comparable with those in plasma samples." circulation_biomarker_diagnosis_up hsa-mir-133a-2 Myocardial Infarction 21881276 "The miR-133 levels in plasma from AMI patients exhibited a 4.4-fold increase compared with control subjects (p=0.006). Moreover, the increased miR-133 levels in whole blood were comparable with those in plasma samples." circulation_biomarker_diagnosis_up hsa-mir-133b Myocardial Infarction 21881276 "The miR-133 levels in plasma from AMI patients exhibited a 4.4-fold increase compared with control subjects (p=0.006). Moreover, the increased miR-133 levels in whole blood were comparable with those in plasma samples." circulation_biomarker_diagnosis_up hsa-mir-328 Myocardial Infarction 21881276 "miR-328 levels in plasma and whole blood of AMI patients were markedly increased by 10.9-fold and 16.1-fold, respectively, compared to those in control subjects (p=0.033 and p<0.001)." circulation_biomarker_diagnosis_up hsa-mir-142 "Scleroderma, Systemic" 21883400 "Serum miR-142-3p levels in patients with SSc (systemic sclerosis) were significantly higher than in patients with SSD (scleroderma spectrum disorder), SLE (systemic lupus erythematosus) or DM (dermatomyositis), and healthy control groups. Patients with increased miR-142-3p levels tended to have a short sublingual frenulum." circulation_biomarker_diagnosis_up hsa-mir-122 "Fatty Liver, Alcoholic" 21886843 "Serum levels of miR-122, miR-34a and miR-16 were significantly higher in NAFLD patients than in controls. miR-122 and miR-34a levels positively correlated with disease severity from simple steatosis to steatohepatitis." circulation_biomarker_diagnosis_up hsa-mir-122 Hepatitis C Virus Infection 21886843 "Extracellular levels of circulating miRNAs, miR-122, miR-34a and to a lesser extent miR-16, steadily increased during the course of HCV infection." circulation_biomarker_diagnosis_up hsa-mir-16-1 "Fatty Liver, Alcoholic" 21886843 "Serum levels of miR-122, miR-34a and miR-16 were significantly higher in NAFLD patients than in controls. miR-122 and miR-34a levels positively correlated with disease severity from simple steatosis to steatohepatitis." circulation_biomarker_diagnosis_up hsa-mir-16-1 Hepatitis C Virus Infection 21886843 "Extracellular levels of circulating miRNAs, miR-122, miR-34a and to a lesser extent miR-16, steadily increased during the course of HCV infection." circulation_biomarker_diagnosis_up hsa-mir-16-2 "Fatty Liver, Alcoholic" 21886843 "Serum levels of miR-122, miR-34a and miR-16 were significantly higher in NAFLD patients than in controls. miR-122 and miR-34a levels positively correlated with disease severity from simple steatosis to steatohepatitis." circulation_biomarker_diagnosis_up hsa-mir-16-2 Hepatitis C Virus Infection 21886843 "Extracellular levels of circulating miRNAs, miR-122, miR-34a and to a lesser extent miR-16, steadily increased during the course of HCV infection." circulation_biomarker_diagnosis_up hsa-mir-34a "Fatty Liver, Alcoholic" 21886843 "Serum levels of miR-122, miR-34a and miR-16 were significantly higher in NAFLD patients than in controls. miR-122 and miR-34a levels positively correlated with disease severity from simple steatosis to steatohepatitis." circulation_biomarker_diagnosis_up hsa-mir-34a Hepatitis C Virus Infection 21886843 "Extracellular levels of circulating miRNAs, miR-122, miR-34a and to a lesser extent miR-16, steadily increased during the course of HCV infection." circulation_biomarker_diagnosis_up hsa-mir-155 Lung Neoplasms 21904633 "The levels of miR-155, miR-197, and miR-182 in the plasma of lung cancer including stage I patients were significantly elevated compared with controls (P<0.001). The combination of these 3 miRNAs yielded 81.33% sensitivity and 86.76% specificity in discriminating lung cancer patients from controls. The levels of miR-155 and miR-197 were higher in the plasma from lung cancer patients with metastasis than in those without metastasis (P<0.05) and were significantly decreased in responsive patients during chemotherapy (P<0.001)." circulation_biomarker_diagnosis_up hsa-mir-182 Lung Neoplasms 21904633 "The levels of miR-155, miR-197, and miR-182 in the plasma of lung cancer including stage I patients were significantly elevated compared with controls (P<0.001). The combination of these 3 miRNAs yielded 81.33% sensitivity and 86.76% specificity in discriminating lung cancer patients from controls. The levels of miR-155 and miR-197 were higher in the plasma from lung cancer patients with metastasis than in those without metastasis (P<0.05) and were significantly decreased in responsive patients during chemotherapy (P<0.001)." circulation_biomarker_diagnosis_up hsa-mir-197 Lung Neoplasms 21904633 "The levels of miR-155, miR-197, and miR-182 in the plasma of lung cancer including stage I patients were significantly elevated compared with controls (P<0.001). The combination of these 3 miRNAs yielded 81.33% sensitivity and 86.76% specificity in discriminating lung cancer patients from controls. The levels of miR-155 and miR-197 were higher in the plasma from lung cancer patients with metastasis than in those without metastasis (P<0.05) and were significantly decreased in responsive patients during chemotherapy (P<0.001)." circulation_biomarker_diagnosis_up hsa-let-7e Hypertension 21924071 "MiR-296-5p (Fold change 0.47, P = 0.013) and miR-133b (Fold change 0.57, P = 0.033) were consistently down-regulated in the patient plasma, whereas let-7e (Fold change 1.62, P = 0.009) and hcmv-miR-UL112 (Fold change 2.72, P = 0.004), one human cytomegalovirus encoded microRNAs, were up-regulated in the patient samples." circulation_biomarker_diagnosis_up hsa-mir-134 Pulmonary Embolism 21943159 "Plasma miRNA-134 (miR-134) level was significantly higher in the APE patients than in the healthy controls or non-APE patients. The ROC curve showed that plasma miR-134 was a specific diagnostic predictor of APE with an area under the curve of 0.833 (95% confidence interval, 0.737 to 0.929; P<0.001). The findings indicated that plasma miR-134 could be an important biomarker for the diagnosis of APE." circulation_biomarker_diagnosis_up hsa-mir-29a Liver Cirrhosis 21946200 MiR-29 directly suppresses the expression of a variety of extracellular matrix components and regulates signaling pathways associated with fibrosis. The serum level of miR-29 in patients with liver disease is consistent with the degree of liver cirrhosis. circulation_biomarker_diagnosis_up hsa-mir-29b-1 Liver Cirrhosis 21946200 MiR-29 directly suppresses the expression of a variety of extracellular matrix components and regulates signaling pathways associated with fibrosis. The serum level of miR-29 in patients with liver disease is consistent with the degree of liver cirrhosis. circulation_biomarker_diagnosis_up hsa-mir-29b-2 Liver Cirrhosis 21946200 MiR-29 directly suppresses the expression of a variety of extracellular matrix components and regulates signaling pathways associated with fibrosis. The serum level of miR-29 in patients with liver disease is consistent with the degree of liver cirrhosis. circulation_biomarker_diagnosis_up hsa-mir-29c Liver Cirrhosis 21946200 MiR-29 directly suppresses the expression of a variety of extracellular matrix components and regulates signaling pathways associated with fibrosis. The serum level of miR-29 in patients with liver disease is consistent with the degree of liver cirrhosis. circulation_biomarker_diagnosis_up hsa-mir-106b "Carcinoma, Renal Cell" 21984948 "Up-regulation in serum and tissue of RCC patients: miR-7-1*, miR-93, miR-106b*, miR-210, miR-320b, miR-1233 and miR-1290" circulation_biomarker_diagnosis_up hsa-mir-1233-1 "Carcinoma, Renal Cell" 21984948 "Up-regulation in serum and tissue of RCC patients: miR-7-1*, miR-93, miR-106b*, miR-210, miR-320b, miR-1233 and miR-1290" circulation_biomarker_diagnosis_up hsa-mir-1233-2 "Carcinoma, Renal Cell" 21984948 "Up-regulation in serum and tissue of RCC patients: miR-7-1*, miR-93, miR-106b*, miR-210, miR-320b, miR-1233 and miR-1290" circulation_biomarker_diagnosis_up hsa-mir-1290 "Carcinoma, Renal Cell" 21984948 "Up-regulation in serum and tissue of RCC patients: miR-7-1*, miR-93, miR-106b*, miR-210, miR-320b, miR-1233 and miR-1290" circulation_biomarker_diagnosis_up hsa-mir-210 "Carcinoma, Renal Cell" 21984948 "Up-regulation in serum and tissue of RCC patients: miR-7-1*, miR-93, miR-106b*, miR-210, miR-320b, miR-1233 and miR-1290" circulation_biomarker_diagnosis_up hsa-mir-320b-1 "Carcinoma, Renal Cell" 21984948 "Up-regulation in serum and tissue of RCC patients: miR-7-1*, miR-93, miR-106b*, miR-210, miR-320b, miR-1233 and miR-1290" circulation_biomarker_diagnosis_up hsa-mir-320b-2 "Carcinoma, Renal Cell" 21984948 "Up-regulation in serum and tissue of RCC patients: miR-7-1*, miR-93, miR-106b*, miR-210, miR-320b, miR-1233 and miR-1290" circulation_biomarker_diagnosis_up hsa-mir-7-1 "Carcinoma, Renal Cell" 21984948 "Up-regulation in serum and tissue of RCC patients: miR-7-1*, miR-93, miR-106b*, miR-210, miR-320b, miR-1233 and miR-1290" circulation_biomarker_diagnosis_up hsa-mir-93 "Carcinoma, Renal Cell" 21984948 "Up-regulation in serum and tissue of RCC patients: miR-7-1*, miR-93, miR-106b*, miR-210, miR-320b, miR-1233 and miR-1290" circulation_biomarker_diagnosis_up hsa-mir-155 "Tuberculosis, Pulmonary" 22037148 Analysis of microRNA expression profiling identifies miR-155 and miR-155* as potential diagnostic markers for active tuberculosis. circulation_biomarker_diagnosis_up hsa-mir-18a Pancreatic Neoplasms 22045190 The expression of miR-18a was significantly higher in pancreatic cancer tissues (P=0.012) and pancreatic cancer cell lines (P=0.015) than in normal tissues and fibroblasts. Plasma concentrations of miR-18a were significantly higher in pancreatic cancer patients than in controls (P<0.0001). The value of the area under the receiver-operating characteristic curve (AUC) was 0.9369. Plasma levels of miR-18a were significantly lower in postoperative samples than in preoperative samples (P=0.0077). circulation_biomarker_diagnosis_up hsa-mir-192 Liver Injury 22045675 Serum miR-122 and miR-192 were substantially higher in APAP-ALI patients. circulation_biomarker_diagnosis_up hsa-mir-223 "Leukemia, Promyelocytic, Acute" 22053279 overexpression circulation_biomarker_diagnosis_up hsa-mir-326 "Diabetes Mellitus, Type 1" 22069274 Increased expression of microRNA miR-326 in type 1 diabetic patients with ongoing islet autoimmunity. circulation_biomarker_diagnosis_up hsa-mir-210 Preeclampsia 22095477 Serum expression level of miR-210 was up-regulated in preeclampsia patients. circulation_biomarker_diagnosis_up hsa-mir-100 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 22099053 "A significant association was observed between higher expression levels of miR-196b and T-ALL, miR-100 and patients with low white blood cell count at diagnosis and t(12;21) positive ALL." circulation_biomarker_diagnosis_up hsa-mir-196b "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 22099053 "A significant association was observed between higher expression levels of miR-196b and T-ALL, miR-100 and patients with low white blood cell count at diagnosis and t(12;21) positive ALL." circulation_biomarker_diagnosis_up hsa-mir-22 Heart Failure 22120965 significantly increased serum level circulation_biomarker_diagnosis_up hsa-mir-320a Heart Failure 22120965 significantly increased serum level circulation_biomarker_diagnosis_up hsa-mir-423 Heart Failure 22120965 miR-423-5p: significantly increased serum level circulation_biomarker_diagnosis_up hsa-mir-92b Heart Failure 22120965 significantly increased serum level circulation_biomarker_diagnosis_up hsa-mir-1266 Psoriasis 22133505 Increased serum levels of miR-1266 in patients with psoriasis vulgaris. circulation_biomarker_diagnosis_up hsa-mir-1 Cardiovascular Diseases [unspecific] 22135162 miR-1 and miR-133 are highly expressed in cardiomyocytes and their precursors and regulate cardiomyogenesis. circulation_biomarker_diagnosis_up hsa-mir-133 Cardiovascular Diseases [unspecific] 22135162 miR-1 and miR-133 are highly expressed in cardiomyocytes and their precursors and regulate cardiomyogenesis. circulation_biomarker_diagnosis_up hsa-mir-140 Osteoarthritis 22143896 the expression of both miR-140-5p and miR-455-3p was increased in OA cartilage. circulation_biomarker_diagnosis_up hsa-mir-455 Osteoarthritis 22143896 the expression of both miR-140-5p and miR-455-3p was increased in OA cartilage. circulation_biomarker_diagnosis_up hsa-mir-92a-1 Myocardial Infarction 22153007 "In STEMI (ST-segment elevation myocardial infarction) patients, the expression of circulating miR-92a is up-regulated. PCI therapy may suppress such up-regulation. Survival rate is higher in patients showing down-regulation of miR-92a. Our data suggest that miR-92a might have potential for diagnosis and therapeutic application in the prevention and treatment of STEMI." circulation_biomarker_diagnosis_up hsa-mir-92a-2 Myocardial Infarction 22153007 "In STEMI (ST-segment elevation myocardial infarction) patients, the expression of circulating miR-92a is up-regulated. PCI therapy may suppress such up-regulation. Survival rate is higher in patients showing down-regulation of miR-92a. Our data suggest that miR-92a might have potential for diagnosis and therapeutic application in the prevention and treatment of STEMI." circulation_biomarker_diagnosis_up hsa-mir-103a-1 Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-103a-2 Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-103b-1 Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-103b-2 Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-130b Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-181a-1 Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-181a-2 Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-24-1 Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-24-2 Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-26a-1 Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-26a-2 Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-342 Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-574 Preeclampsia 22187671 "Seven microRNAs, namely miR-24, miR-26a, miR-103, miR-130b, miR-181a, miR-342-3p, and miR-574-5p, were validated to be elevated in plasma from severe pre-eclamptic pregnancies by using real-time quantitative stem-loop reverse-transcription polymerase chain reaction analysis." circulation_biomarker_diagnosis_up hsa-mir-22 Multiple Sclerosis 22231906 "Six plasma miRNA (miR-614, miR-572, miR-648, miR-1826, miR-422a and miR-22) that were significantly up-regulated and one plasma miRNA (miR-1979) that was significantly down-regulated in MS individuals." circulation_biomarker_diagnosis_up hsa-mir-422a Multiple Sclerosis 22231906 "Six plasma miRNA (miR-614, miR-572, miR-648, miR-1826, miR-422a and miR-22) that were significantly up-regulated and one plasma miRNA (miR-1979) that was significantly down-regulated in MS individuals." circulation_biomarker_diagnosis_up hsa-mir-572 Multiple Sclerosis 22231906 "Six plasma miRNA (miR-614, miR-572, miR-648, miR-1826, miR-422a and miR-22) that were significantly up-regulated and one plasma miRNA (miR-1979) that was significantly down-regulated in MS individuals." circulation_biomarker_diagnosis_up hsa-mir-614 Multiple Sclerosis 22231906 "Six plasma miRNA (miR-614, miR-572, miR-648, miR-1826, miR-422a and miR-22) that were significantly up-regulated and one plasma miRNA (miR-1979) that was significantly down-regulated in MS individuals." circulation_biomarker_diagnosis_up hsa-mir-648 Multiple Sclerosis 22231906 "Six plasma miRNA (miR-614, miR-572, miR-648, miR-1826, miR-422a and miR-22) that were significantly up-regulated and one plasma miRNA (miR-1979) that was significantly down-regulated in MS individuals." circulation_biomarker_diagnosis_up hsa-let-7a-1 Breast Neoplasms 22242178 let-7a* is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-let-7a-2 Breast Neoplasms 22242178 let-7a* is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-let-7a-3 Breast Neoplasms 22242178 let-7a* is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-106b Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-1323 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-202 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-335 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-4257 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-4306 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-497 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-516b-1 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-516b-2 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-922 Breast Neoplasms 22242178 The miRNA is up-regulated in whole blood of breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-103a-1 Mesothelioma 22253921 miR-103 was identified as a potential biomarker for malignant mesothelioma circulation_biomarker_diagnosis_up hsa-mir-103a-2 Mesothelioma 22253921 miR-103 was identified as a potential biomarker for malignant mesothelioma circulation_biomarker_diagnosis_up hsa-mir-125b "Leukemia, Lymphoblastic" 22335948 "These three subtypes of leukemia could be identified by unsupervised hierarchical cluster analysis of microRNA expression and had specific up-regulation of miR-335, miR-126 and miR-125b, respectively." circulation_biomarker_diagnosis_up hsa-mir-126 "Leukemia, Lymphoblastic" 22335948 "These three subtypes of leukemia could be identified by unsupervised hierarchical cluster analysis of microRNA expression and had specific up-regulation of miR-335, miR-126 and miR-125b, respectively." circulation_biomarker_diagnosis_up hsa-mir-335 "Leukemia, Lymphoblastic" 22335948 "These three subtypes of leukemia could be identified by unsupervised hierarchical cluster analysis of microRNA expression and had specific up-regulation of miR-335, miR-126 and miR-125b, respectively." circulation_biomarker_diagnosis_up hsa-mir-20a Breast Neoplasms 22350790 "Levels of preoperative serum miR-20a and miR-21 were significantly higher in patients with breast cancer and benign disease than in healthy women (p = 0.0001), but only serum miR-214 could discriminate malignant from benign tumors and healthy controls (p = 0.0001) with an area under the curve of 0.878 and 0.883 in ROC analysis, respectively." circulation_biomarker_diagnosis_up hsa-mir-21 Breast Neoplasms 22350790 "Levels of preoperative serum miR-20a and miR-21 were significantly higher in patients with breast cancer and benign disease than in healthy women (p = 0.0001), but only serum miR-214 could discriminate malignant from benign tumors and healthy controls (p = 0.0001) with an area under the curve of 0.878 and 0.883 in ROC analysis, respectively." circulation_biomarker_diagnosis_up hsa-mir-214 Breast Neoplasms 22350790 "Levels of preoperative serum miR-20a and miR-21 were significantly higher in patients with breast cancer and benign disease than in healthy women (p = 0.0001), but only serum miR-214 could discriminate malignant from benign tumors and healthy controls (p = 0.0001) with an area under the curve of 0.878 and 0.883 in ROC analysis, respectively." circulation_biomarker_diagnosis_up hsa-mir-21 Esophageal Neoplasms 22354855 "Serum concentration of miRNA-21 in ESCC patients was significantly higher than that in healthy controls (P<0.001). A significant reduction in the serum miR-21 levels was observed in the postoperative samples versus the preoperative samples (P=0.003). Furthermore, miRNA-21 levels were significantly reduced in ESCC patients who responded to chemotherapy (P=0.003), whereas no significant change was observed in the non-responders." circulation_biomarker_diagnosis_up hsa-mir-145 Cerebral Ischemia 22370881 Circulatory microRNA-145 expression is increased in cerebral ischemia. circulation_biomarker_diagnosis_up hsa-mir-106a Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-107 Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-126 Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-16-1 Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-16-2 Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-191 Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-199a-1 Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-199a-2 Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-200c Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-23a Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-29a Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-362 Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-532 Crohn Disease 22386737 The miRNA showed significantly higher levels in the blood from patients with CD compared with the healthy controls. circulation_biomarker_diagnosis_up hsa-mir-103a-1 Breast Neoplasms 22387599 significantly increased in serum of breast cancer patients. circulation_biomarker_diagnosis_up hsa-mir-222 Breast Neoplasms 22387599 significantly increased in serum of breast cancer patients. circulation_biomarker_diagnosis_up hsa-mir-23a Breast Neoplasms 22387599 significantly increased in serum of breast cancer patients. circulation_biomarker_diagnosis_up hsa-mir-23b Breast Neoplasms 22387599 significantly increased in serum of breast cancer patients. circulation_biomarker_diagnosis_up hsa-mir-24-1 Breast Neoplasms 22387599 significantly increased in serum of breast cancer patients. circulation_biomarker_diagnosis_up hsa-mir-25 Breast Neoplasms 22387599 significantly increased in serum of breast cancer patients. circulation_biomarker_diagnosis_up hsa-mir-29a Breast Neoplasms 22387599 significantly increased in serum of breast cancer patients. circulation_biomarker_diagnosis_up hsa-mir-210 "Carcinoma, Hepatocellular" 22387901 "Downregulation of miR-210 expression inhibits proliferation, induces apoptosis and enhances radiosensitivity in hypoxic human hepatoma cells in vitro." circulation_biomarker_diagnosis_up hsa-mir-106b Eosinophilic Esophagitis 22391115 miR-106b*: upregulated circulation_biomarker_diagnosis_up hsa-mir-132 Eosinophilic Esophagitis 22391115 upregulated circulation_biomarker_diagnosis_up hsa-mir-142 Eosinophilic Esophagitis 22391115 upregulated circulation_biomarker_diagnosis_up hsa-mir-146a Eosinophilic Esophagitis 22391115 "Plasma analysis of the most upregulated esophageal miRNAs identified miR-146a, miR-146b, and miR-223 as the most differentially expressed miRNAs in the plasma." circulation_biomarker_diagnosis_up hsa-mir-146b Eosinophilic Esophagitis 22391115 "Plasma analysis of the most upregulated esophageal miRNAs identified miR-146a, miR-146b, and miR-223 as the most differentially expressed miRNAs in the plasma." circulation_biomarker_diagnosis_up hsa-mir-21 Eosinophilic Esophagitis 22391115 "One of the most upregulated miRNA, which strongly correlated with esophageal eosinophil levels." circulation_biomarker_diagnosis_up hsa-mir-212 Eosinophilic Esophagitis 22391115 upregulated circulation_biomarker_diagnosis_up hsa-mir-222 Eosinophilic Esophagitis 22391115 miR-222*: upregulated circulation_biomarker_diagnosis_up hsa-mir-223 Eosinophilic Esophagitis 22391115 "One of the most upregulated miRNA, which strongly correlated with esophageal eosinophil levels. And miR-223 is one of the most differentially expressed miRNAs in the plasma." circulation_biomarker_diagnosis_up hsa-mir-29b-1 Eosinophilic Esophagitis 22391115 upregulated circulation_biomarker_diagnosis_up hsa-mir-29b-2 Eosinophilic Esophagitis 22391115 upregulated circulation_biomarker_diagnosis_up hsa-mir-339 Eosinophilic Esophagitis 22391115 miR-339-5p: upregulated circulation_biomarker_diagnosis_up hsa-mir-592 Eosinophilic Esophagitis 22391115 upregulated circulation_biomarker_diagnosis_up hsa-mir-7-1 Eosinophilic Esophagitis 22391115 upregulated circulation_biomarker_diagnosis_up hsa-mir-7-2 Eosinophilic Esophagitis 22391115 upregulated circulation_biomarker_diagnosis_up hsa-mir-7-3 Eosinophilic Esophagitis 22391115 upregulated circulation_biomarker_diagnosis_up hsa-mir-92a-1 Eosinophilic Esophagitis 22391115 miR-92a-1*: upregulated circulation_biomarker_diagnosis_up hsa-mir-323a Ectopic Pregnancy 22395025 "Concentrations of serum hCG, progesterone, miR-517a, miR-519d, and miR-525-3p were significantly lower in EP and SA cases than in VIP cases. In contrast, the concentration of miR-323-3p was significantly increased in EP cases, compared with SA and VIP cases. As a single marker, miR-323-3p had the highest sensitivity of 37.0% (at a fixed specificity of 90%)." circulation_biomarker_diagnosis_up hsa-mir-130b "Carcinoma, Hepatocellular" 22403344 "Serum miR-15b, miR-21, miR-130b and miR-183 highly expressed in tumours. Combined miR-15b and miR-130b demonstrated as a classifier for HCC detection, yielding a receiver operating characteristic curve area of 0.98 (98.2% sensitivity and 91.5% specificity)." circulation_biomarker_diagnosis_up hsa-mir-15b "Carcinoma, Hepatocellular" 22403344 "Serum miR-15b, miR-21, miR-130b and miR-183 highly expressed in tumours. Combined miR-15b and miR-130b demonstrated as a classifier for HCC detection, yielding a receiver operating characteristic curve area of 0.98 (98.2% sensitivity and 91.5% specificity)." circulation_biomarker_diagnosis_up hsa-mir-183 "Carcinoma, Hepatocellular" 22403344 "Serum miR-15b, miR-21, miR-130b and miR-183 highly expressed in tumours. Combined miR-15b and miR-130b demonstrated as a classifier for HCC detection, yielding a receiver operating characteristic curve area of 0.98 (98.2% sensitivity and 91.5% specificity)." circulation_biomarker_diagnosis_up hsa-mir-21 "Carcinoma, Hepatocellular" 22403344 "Serum miR-15b, miR-21, miR-130b and miR-183 highly expressed in tumours. Combined miR-15b and miR-130b demonstrated as a classifier for HCC detection, yielding a receiver operating characteristic curve area of 0.98 (98.2% sensitivity and 91.5% specificity)." circulation_biomarker_diagnosis_up hsa-mir-126 "Carcinoma, Renal Cell" 22440013 miR-126*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-134 "Carcinoma, Renal Cell" 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-144 "Carcinoma, Renal Cell" 22440013 miR-144*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-151a "Carcinoma, Renal Cell" 22440013 miR-151-30: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-151b "Carcinoma, Renal Cell" 22440013 miR-151-30: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-203 "Carcinoma, Renal Cell" 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-26b "Carcinoma, Renal Cell" 22440013 miR-26b*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-29c "Carcinoma, Renal Cell" 22440013 miR-29c*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-320a "Carcinoma, Renal Cell" 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-339 "Carcinoma, Renal Cell" 22440013 miR-339-3p: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-365a "Carcinoma, Renal Cell" 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-365b "Carcinoma, Renal Cell" 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-378a "Carcinoma, Renal Cell" 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-425 "Carcinoma, Renal Cell" 22440013 miR-425*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-454 "Carcinoma, Renal Cell" 22440013 miR-454*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-571 "Carcinoma, Renal Cell" 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-625 "Carcinoma, Renal Cell" 22440013 miR-625*: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-629 "Carcinoma, Renal Cell" 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-655 "Carcinoma, Renal Cell" 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-760 "Carcinoma, Renal Cell" 22440013 Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. circulation_biomarker_diagnosis_up hsa-mir-148a Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM.High levels of miR-20a and miR-148a were related to shorter relapse-free survival. circulation_biomarker_diagnosis_up hsa-mir-181a-1 Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM. circulation_biomarker_diagnosis_up hsa-mir-181a-2 Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM. circulation_biomarker_diagnosis_up hsa-mir-20a Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM. circulation_biomarker_diagnosis_up hsa-mir-221 Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM.High levels of miR-20a and miR-148a were related to shorter relapse-free survival. circulation_biomarker_diagnosis_up hsa-mir-625 Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM. circulation_biomarker_diagnosis_up hsa-mir-99b Multiple Myeloma 22447484 Plasma level was significantly upregulated in MM. circulation_biomarker_diagnosis_up hsa-mir-29b "Leukemia, Lymphoblastic, Acute" 22456238 "BCR-ABL1 positive cases, in contrast to negative ones, were characterized by slightly, but still significantly, higher expression levels of miR-29b." circulation_biomarker_diagnosis_up hsa-let-7e Thyroid Neoplasms 22472564 "The expression of serum let-7e, miR-151-5p, and miR-222 was significantly increased in PTC (papillary thyroid carcinomas ) cases relative to benign cases and healthy controls. Serum let-7e, miR-151-5p, and miR-222 levels were found to be well correlated with certain clinicopathological variables, such as nodal status, tumor size, multifocal lesion status, and Tumor-Node-Metastasis stage." circulation_biomarker_diagnosis_up hsa-mir-151a Thyroid Neoplasms 22472564 "The expression of serum let-7e, miR-151-5p, and miR-222 was significantly increased in PTC (papillary thyroid carcinomas ) cases relative to benign cases and healthy controls. Serum let-7e, miR-151-5p, and miR-222 levels were found to be well correlated with certain clinicopathological variables, such as nodal status, tumor size, multifocal lesion status, and Tumor-Node-Metastasis stage." circulation_biomarker_diagnosis_up hsa-mir-151b Thyroid Neoplasms 22472564 "The expression of serum let-7e, miR-151-5p, and miR-222 was significantly increased in PTC (papillary thyroid carcinomas ) cases relative to benign cases and healthy controls. Serum let-7e, miR-151-5p, and miR-222 levels were found to be well correlated with certain clinicopathological variables, such as nodal status, tumor size, multifocal lesion status, and Tumor-Node-Metastasis stage." circulation_biomarker_diagnosis_up hsa-mir-222 Thyroid Neoplasms 22472564 "The expression of serum let-7e, miR-151-5p, and miR-222 was significantly increased in PTC (papillary thyroid carcinomas ) cases relative to benign cases and healthy controls. Serum let-7e, miR-151-5p, and miR-222 levels were found to be well correlated with certain clinicopathological variables, such as nodal status, tumor size, multifocal lesion status, and Tumor-Node-Metastasis stage." circulation_biomarker_diagnosis_up hsa-mir-21 "Lymphoma, Non-Hodgkin" 22487708 B-cell activation induced microRNA-21 is elevated in circulating B cells preceding the diagnosis of AIDS-related non-Hodgkin lymphomas. circulation_biomarker_diagnosis_up hsa-mir-155 "Adenocarcinoma, Pancreatic Ductal" 22513294 "Quantification by real-time quantitative polymerase chain reaction revealed that miR-155, miR-21, and miR-210 were higher in serum of PDAC rats,similar to plasma of patients with PDAC" circulation_biomarker_diagnosis_up hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 22513294 "Quantification by real-time quantitative polymerase chain reaction revealed that miR-155, miR-21, and miR-210 were higher in serum of PDAC rats,similar to plasma of patients with PDAC" circulation_biomarker_diagnosis_up hsa-mir-210 "Adenocarcinoma, Pancreatic Ductal" 22513294 "Quantification by real-time quantitative polymerase chain reaction revealed that miR-155, miR-21, and miR-210 were higher in serum of PDAC rats,similar to plasma of patients with PDAC" circulation_biomarker_diagnosis_up hsa-mir-378a "Carcinoma, Renal Cell" 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. circulation_biomarker_diagnosis_up hsa-mir-378b "Carcinoma, Renal Cell" 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. circulation_biomarker_diagnosis_up hsa-mir-378c "Carcinoma, Renal Cell" 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. circulation_biomarker_diagnosis_up hsa-mir-378d-1 "Carcinoma, Renal Cell" 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. circulation_biomarker_diagnosis_up hsa-mir-378d-2 "Carcinoma, Renal Cell" 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. circulation_biomarker_diagnosis_up hsa-mir-378e "Carcinoma, Renal Cell" 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. circulation_biomarker_diagnosis_up hsa-mir-378f "Carcinoma, Renal Cell" 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. circulation_biomarker_diagnosis_up hsa-mir-378g "Carcinoma, Renal Cell" 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. circulation_biomarker_diagnosis_up hsa-mir-378h "Carcinoma, Renal Cell" 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. circulation_biomarker_diagnosis_up hsa-mir-378i "Carcinoma, Renal Cell" 22542158 The level of miR-378 was significantly increased in serum of ccRCC patients. circulation_biomarker_diagnosis_up hsa-mir-122 Coronary Artery Disease 22587332 Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease. circulation_biomarker_diagnosis_up hsa-mir-122 Hyperlipidemia 22587332 Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease. circulation_biomarker_diagnosis_up hsa-mir-370 Coronary Artery Disease 22587332 Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease. circulation_biomarker_diagnosis_up hsa-mir-370 Hyperlipidemia 22587332 Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease. circulation_biomarker_diagnosis_up hsa-mir-103a-1 Breast Neoplasms 22588912 "The serum levels of miR-103 expression were significantly higher in the cancer patients than in the healthy control group (P<0.01). In the cancer patients, high miR-103 expression was significantly correlated to advanced clinical stage (P<0.05) and lymph node metastasis (P<0.05)." circulation_biomarker_diagnosis_up hsa-mir-103a-2 Breast Neoplasms 22588912 "The serum levels of miR-103 expression were significantly higher in the cancer patients than in the healthy control group (P<0.01). In the cancer patients, high miR-103 expression was significantly correlated to advanced clinical stage (P<0.05) and lymph node metastasis (P<0.05)." circulation_biomarker_diagnosis_up hsa-mir-103b-1 Breast Neoplasms 22588912 "The serum levels of miR-103 expression were significantly higher in the cancer patients than in the healthy control group (P<0.01). In the cancer patients, high miR-103 expression was significantly correlated to advanced clinical stage (P<0.05) and lymph node metastasis (P<0.05)." circulation_biomarker_diagnosis_up hsa-mir-103b-2 Breast Neoplasms 22588912 "The serum levels of miR-103 expression were significantly higher in the cancer patients than in the healthy control group (P<0.01). In the cancer patients, high miR-103 expression was significantly correlated to advanced clinical stage (P<0.05) and lymph node metastasis (P<0.05)." circulation_biomarker_diagnosis_up hsa-mir-625 Mesothelioma 22617246 Increased circulating miR-625-3p is a potential biomarker for patients with malignant pleural mesothelioma. circulation_biomarker_diagnosis_up hsa-mir-126 Systemic Lupus Erythematosus 22683424 miR-126 was specifically enriched only in the blood of the SLE patients circulation_biomarker_diagnosis_up hsa-mir-1-1 Myocardial Infarction 22719221 Increased miR-1 and decreased miR-126 in plasma from patients with AMI after the onset of symptoms compared with healthy subjects were found. circulation_biomarker_diagnosis_up hsa-mir-1-2 Myocardial Infarction 22719221 Increased miR-1 and decreased miR-126 in plasma from patients with AMI after the onset of symptoms compared with healthy subjects were found. circulation_biomarker_diagnosis_up hsa-mir-21 Esophageal Neoplasms 22799367 "Serum miR-21 expression in ESCC samples was significantly higher than in paired cancer-free samples (P <0.05). Metastasis was associated with mir-21 expression in serum (P <0.05), ESCC patients with metastasis having 8.4-fold higher serum miR-21 concentrations than healthy controls." circulation_biomarker_diagnosis_up hsa-let-7b Breast Neoplasms 22821209 "Potential biomarker microRNAs were identified, including let-7b, let-7g and miR-18b, with higher circulating levels associated with tumours." circulation_biomarker_diagnosis_up hsa-let-7g Breast Neoplasms 22821209 "Potential biomarker microRNAs were identified, including let-7b, let-7g and miR-18b, with higher circulating levels associated with tumours." circulation_biomarker_diagnosis_up hsa-mir-18b Breast Neoplasms 22821209 "Potential biomarker microRNAs were identified, including let-7b, let-7g and miR-18b, with higher circulating levels associated with tumours." circulation_biomarker_diagnosis_up hsa-mir-21 Gastric Neoplasms 22860003 "The plasma levels of miR-223 (P<0.001) and miR-21 (P<0.001) were significantly higher in GC patients than in healthy controls, while miR-218 (P<0.001) was significantly lower. The ROC analyses yielded the AUC values of 0.9089 for miR-223, 0.7944 for miR-21 and 0.7432 for miR-218, and combined ROC analysis revealed the highest AUC value of 0.9531 in discriminating GC patients from healthy controls." circulation_biomarker_diagnosis_up hsa-mir-223 Gastric Neoplasms 22860003 "The plasma levels of miR-223 (P<0.001) and miR-21 (P<0.001) were significantly higher in GC patients than in healthy controls, while miR-218 (P<0.001) was significantly lower. The ROC analyses yielded the AUC values of 0.9089 for miR-223, 0.7944 for miR-21 and 0.7432 for miR-218, and combined ROC analysis revealed the highest AUC value of 0.9531 in discriminating GC patients from healthy controls." circulation_biomarker_diagnosis_up hsa-mir-18a "Carcinoma, Hepatocellular" 22865399 Serum miR-18a was significantly higher in HBV patients with HCC than healthy controls (p < 0.01). circulation_biomarker_diagnosis_up hsa-mir-21 Colorectal Carcinoma 22868372 "In the plasma group, miR-21 differentiated CRC patients from controls with 90% specificity and sensitivity." circulation_biomarker_diagnosis_up hsa-mir-21 Aortic Stenosis 22882958 The myocardial and plasma levels of miR-21 were significantly higher in the AS patients compared with the controls and correlated directly with the echocardiographic mean transvalvular gradients. circulation_biomarker_diagnosis_up hsa-mir-155 "Leukemia-Lymphoma, Adult T-Cell" 22884882 The high and low plasma levels of miR-155 and miR-126 changed with ATL stage. circulation_biomarker_diagnosis_up hsa-mir-141 Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_up hsa-mir-375 Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_up hsa-mir-378a Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_up hsa-mir-378b Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_up hsa-mir-378c Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_up hsa-mir-378d-1 Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_up hsa-mir-378d-2 Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_up hsa-mir-378e Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_up hsa-mir-378f Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_up hsa-mir-378g Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_up hsa-mir-378h Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_up hsa-mir-378i Prostate Neoplasms 22887127 "MiR-375, miR-378*, and miR-141 were significantly over-expressed in serum from CRPC patients compared with serum from low-risk localized patients, while miR-409-3p was significantly under-expressed. In prostate primary tumor samples, miR-375 and miR-141 also had significantly higher expression levels compared with those in normal prostate tissue." circulation_biomarker_diagnosis_up hsa-mir-21 Glioblastoma 22891879 Plasma MicroRNA-21 in glioblastoma was significantly higher than controls (p = .02) and decreased significantly in 9 patients (p = .05). One patient with increasing microRNA-21 developed a histopathologically proven recurrence after the second sample collection. circulation_biomarker_diagnosis_up hsa-mir-223 Prostate Neoplasms 22892455 An increase in serum miR-223 and a decrease in miR-125b and miR-146a were observed in group B. circulation_biomarker_diagnosis_up hsa-mir-10b Breast Neoplasms 22906258 Serum Overexpression of MicroRNA-10b in Patients with Bone Metastatic Primary Breast Cancer. circulation_biomarker_diagnosis_up hsa-mir-148b Breast Neoplasms 22927033 "Four miRNAs (miR-148b, miR-376c, miR-409-3p and miR-801) were shown to be significantly upregulated in the plasma of breast cancer patients." circulation_biomarker_diagnosis_up hsa-mir-376c Breast Neoplasms 22927033 "Four miRNAs (miR-148b, miR-376c, miR-409-3p and miR-801) were shown to be significantly upregulated in the plasma of breast cancer patients." circulation_biomarker_diagnosis_up hsa-mir-409 Breast Neoplasms 22927033 "Four miRNAs (miR-148b, miR-376c, miR-409-3p and miR-801) were shown to be significantly upregulated in the plasma of breast cancer patients." circulation_biomarker_diagnosis_up hsa-mir-100 "Carcinoma, Lung, Non-Small-Cell" 22937028 "High expression of miR-100 and low expression of miRNA-93, miRNA-134, miRNA-151 and miRNA-345 were associated with poor survival in both the training and validation cohort." circulation_biomarker_diagnosis_up hsa-mir-141 Breast Neoplasms 22952344 "CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05)." circulation_biomarker_diagnosis_up hsa-mir-200a Breast Neoplasms 22952344 "CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05)." circulation_biomarker_diagnosis_up hsa-mir-200b Breast Neoplasms 22952344 "CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05)." circulation_biomarker_diagnosis_up hsa-mir-200c Breast Neoplasms 22952344 "CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05)." circulation_biomarker_diagnosis_up hsa-mir-203 Breast Neoplasms 22952344 "CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05)." circulation_biomarker_diagnosis_up hsa-mir-210 Breast Neoplasms 22952344 "CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05)." circulation_biomarker_diagnosis_up hsa-mir-375 Breast Neoplasms 22952344 "CTC (circulating tumour cells)-positive had significantly higher levels of miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375 and miR-801 than CTC-negative MBC and controls (P < 0.00001), while miR-768-3p was present in lower amounts in MBC (metastatic breast cancer) cases (P < 0.05)." circulation_biomarker_diagnosis_up hsa-mir-200c Gastric Neoplasms 22954417 The miR-200c blood expression levels in GC patients were significantly higher than in normal controls (p = 0.018). increased miR-200c levels are detected in the blood of gastric cancer patients. MiR-200c has the potential to be a predictor of progression and survival. circulation_biomarker_diagnosis_up hsa-mir-151a Gastric Neoplasms 22956063 Plasma miRNA-199a-3p and miRNA-151-5p were significantly elevated (p < 0.05) and were significantly reduced after surgery (p < 0.05) in gastric cancer patients. circulation_biomarker_diagnosis_up hsa-mir-151b Gastric Neoplasms 22956063 Plasma miRNA-199a-3p and miRNA-151-5p were significantly elevated (p < 0.05) and were significantly reduced after surgery (p < 0.05) in gastric cancer patients. circulation_biomarker_diagnosis_up hsa-mir-199a-1 Gastric Neoplasms 22956063 Plasma miRNA-199a-3p and miRNA-151-5p were significantly elevated (p < 0.05) and were significantly reduced after surgery (p < 0.05) in gastric cancer patients. circulation_biomarker_diagnosis_up hsa-mir-199a-2 Gastric Neoplasms 22956063 Plasma miRNA-199a-3p and miRNA-151-5p were significantly elevated (p < 0.05) and were significantly reduced after surgery (p < 0.05) in gastric cancer patients. circulation_biomarker_diagnosis_up hsa-mir-126 Kidney Diseases [unspecific] 23070235 Circulating levels of inflammation-associated miR-155 and endothelial-enriched miR-126 in patients with end-stage renal disease circulation_biomarker_diagnosis_up hsa-mir-224 Systemic Lupus Erythematosus 23199328 Decreased microRNA(miR)-145 and increased miR-224 expression in T cells from patients with systemic lupus erythematosus involved in lupus immunopathogenesis circulation_biomarker_diagnosis_up hsa-mir-21 Esophageal Neoplasms 23224754 Clinical impact of serum exosomal microRNA-21 as a clinical biomarker in human esophageal squamous cell carcinoma circulation_biomarker_diagnosis_up hsa-mir-132 Inflammation 23264652 "In peptidoglycan (PGN)/TLR2-stimulated THP-1 monocytes, PBMCs, and primary macrophages showed rapid and dramatic miR-132 and miR-212 (miR-132/-212) upregulation." circulation_biomarker_diagnosis_up hsa-mir-212 Inflammation 23264652 "In peptidoglycan (PGN)/TLR2-stimulated THP-1 monocytes, PBMCs, and primary macrophages showed rapid and dramatic miR-132 and miR-212 (miR-132/-212) upregulation." circulation_biomarker_diagnosis_up hsa-mir-200a Ovarian Neoplasms 23272653 Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer circulation_biomarker_diagnosis_up hsa-mir-200b Ovarian Neoplasms 23272653 Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer circulation_biomarker_diagnosis_up hsa-mir-200c Ovarian Neoplasms 23272653 Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer circulation_biomarker_diagnosis_up hsa-mir-15b Fatty Liver [unspecific] 23287814 Upregulation of miR-15b in NAFLD models and in the serum of patients with fatty liver disease circulation_biomarker_diagnosis_up hsa-mir-145 Hypertension 23339529 Overexpression of microRNA-145 in atherosclerotic plaques from hypertensive patients circulation_biomarker_diagnosis_up hsa-mir-155 Breast Neoplasms 23372341 serum;miR-205 was down-regulated and miR-155 was up-regulated in BC patient serum circulation_biomarker_diagnosis_up hsa-mir-205 Breast Neoplasms 23372341 serum;miR-205 was down-regulated and miR-155 was up-regulated in BC patient serum circulation_biomarker_diagnosis_up hsa-mir-141 Prostate Neoplasms 23377530 serum;An elevated serum miR-141 level in patients with bone-metastatic prostate cancer is correlated with more bone lesions circulation_biomarker_diagnosis_up hsa-mir-106b Heart Failure 23388090 "Quantitative real-time polymerase chain reaction (PCR) analysis for a selected panel of miRNAs indicated that circulating levels of miR-16, miR-20b, miR-93, miR-106b, miR-223, and miR-423-5p were significantly increased in response to hypertension-induced heart failure" circulation_biomarker_diagnosis_up hsa-mir-16 Heart Failure 23388090 "Quantitative real-time polymerase chain reaction (PCR) analysis for a selected panel of miRNAs indicated that circulating levels of miR-16, miR-20b, miR-93, miR-106b, miR-223, and miR-423-5p were significantly increased in response to hypertension-induced heart failure" circulation_biomarker_diagnosis_up hsa-mir-20b Heart Failure 23388090 "Quantitative real-time polymerase chain reaction (PCR) analysis for a selected panel of miRNAs indicated that circulating levels of miR-16, miR-20b, miR-93, miR-106b, miR-223, and miR-423-5p were significantly increased in response to hypertension-induced heart failure" circulation_biomarker_diagnosis_up hsa-mir-223 Heart Failure 23388090 "Quantitative real-time polymerase chain reaction (PCR) analysis for a selected panel of miRNAs indicated that circulating levels of miR-16, miR-20b, miR-93, miR-106b, miR-223, and miR-423-5p were significantly increased in response to hypertension-induced heart failure" circulation_biomarker_diagnosis_up hsa-mir-423 Heart Failure 23388090 "Quantitative real-time polymerase chain reaction (PCR) analysis for a selected panel of miRNAs indicated that circulating levels of miR-16, miR-20b, miR-93, miR-106b, miR-223, and miR-423-5p were significantly increased in response to hypertension-induced heart failure" circulation_biomarker_diagnosis_up hsa-mir-93 Heart Failure 23388090 "Quantitative real-time polymerase chain reaction (PCR) analysis for a selected panel of miRNAs indicated that circulating levels of miR-16, miR-20b, miR-93, miR-106b, miR-223, and miR-423-5p were significantly increased in response to hypertension-induced heart failure" circulation_biomarker_diagnosis_up hsa-mir-142 Systemic Lupus Erythematosus 23401079 "Seven miRNAs were statistically significantly differentially expressed in plasma from patients with SLE. The expression of miRNA-142-3p (miR-142-3p) and miR-181a was increased, and the expression of miR-106a, miR-17, miR-20a, miR-203,and miR-92a was decreased" circulation_biomarker_diagnosis_up hsa-mir-181 Systemic Lupus Erythematosus 23401079 "Seven miRNAs were statistically significantly differentially expressed in plasma from patients with SLE. The expression of miRNA-142-3p (miR-142-3p) and miR-181a was increased, and the expression of miR-106a, miR-17, miR-20a, miR-203,and miR-92a was decreased" circulation_biomarker_diagnosis_up hsa-mir-423-5p Heart Failure 23438607 Patients with DCM have elevated plasma miR-423-5p levels. The plasma concentration of miR-423-5p was positively correlated with the level of NT-proBNP. Circulating levels of miR-423-5p could be served as a diagnostic biomarker for heart failure caused by DCM. circulation_biomarker_diagnosis_up hsa-mir-132 Hypertension 23712358 "The miR-132 and miR-212 are highly increased in the heart, aortic wall and kidney of rats with hypertension (159 ¡À 12 mm Hg) and cardiac hypertrophy following chronic AngII infusion." circulation_biomarker_diagnosis_up hsa-mir-212 Hypertension 23712358 "The miR-132 and miR-212 are highly increased in the heart, aortic wall and kidney of rats with hypertension (159 ¡À 12 mm Hg) and cardiac hypertrophy following chronic AngII infusion." circulation_biomarker_diagnosis_up hsa-mir-122 "Fatty Liver, Non-Alcoholic" 23727030 "Serum levels of miRNAs, miR-21, miR-34a, miR-122, and miR-451 were higher in participants with NAFLD. The serum level of miR-122 was correlated with the severity of liver steatosis." circulation_biomarker_diagnosis_up hsa-mir-21 "Fatty Liver, Non-Alcoholic" 23727030 "Serum levels of miRNAs, miR-21, miR-34a, miR-122, and miR-451 were higher in participants with NAFLD. The serum level of miR-122 was correlated with the severity of liver steatosis." circulation_biomarker_diagnosis_up hsa-mir-34a "Fatty Liver, Non-Alcoholic" 23727030 "Serum levels of miRNAs, miR-21, miR-34a, miR-122, and miR-451 were higher in participants with NAFLD. The serum level of miR-122 was correlated with the severity of liver steatosis." circulation_biomarker_diagnosis_up hsa-mir-451 "Fatty Liver, Non-Alcoholic" 23727030 "Serum levels of miRNAs, miR-21, miR-34a, miR-122, and miR-451 were higher in participants with NAFLD. The serum level of miR-122 was correlated with the severity of liver steatosis." circulation_biomarker_diagnosis_up hsa-mir-192 Heart Failure 23743335 "Among the 377 examined microRNAs, the serum level of only miR-192 was significantly upregulated in AMI patients with development of ischemic HF" circulation_biomarker_diagnosis_up hsa-let-7d Alzheimer Disease 23895045 A blood based 12-miRNA signature of Alzheimer disease patients. circulation_biomarker_diagnosis_up hsa-mir-112 Alzheimer Disease 23895045 A blood based 12-miRNA signature of Alzheimer disease patients. circulation_biomarker_diagnosis_up hsa-mir-151a Alzheimer Disease 23895045 A blood based 12-miRNA signature of Alzheimer disease patients. circulation_biomarker_diagnosis_up hsa-mir-161 Alzheimer Disease 23895045 A blood based 12-miRNA signature of Alzheimer disease patients. circulation_biomarker_diagnosis_up hsa-mir-5010 Alzheimer Disease 23895045 A blood based 12-miRNA signature of Alzheimer disease patients. circulation_biomarker_diagnosis_up hsa-mir-221 "Leukemia, Myeloid, Acute" 23895238 Overexpression of primary microRNA 221/222 in acute myeloid leukemia. circulation_biomarker_diagnosis_up hsa-mir-222 "Leukemia, Myeloid, Acute" 23895238 Overexpression of primary microRNA 221/222 in acute myeloid leukemia. circulation_biomarker_diagnosis_up hsa-mir-146a Breast Neoplasms 23898484 Overexpression of circulating miRNA-21 and miRNA-146a in plasma samples of breast cancer patients. circulation_biomarker_diagnosis_up hsa-mir-21 Breast Neoplasms 23898484 Overexpression of circulating miRNA-21 and miRNA-146a in plasma samples of breast cancer patients. circulation_biomarker_diagnosis_up hsa-mir-10b Choriocarcinoma 23933230 "we observed that miR-21 was significantly overexpressed in PDAC, and miR-10b was highly expressed in PanIN II-III." circulation_biomarker_diagnosis_up hsa-mir-146a "Diabetes Mellitus, Type 2" 24023848 circulating miRNA-146a levels were significantly elevated in new-T2DM patients compared with healthy controls. Whether expression of circulating miRNA-146a holds predictive value for T2DM warrants further investigations. circulation_biomarker_diagnosis_up hsa-mir-375 "Adenocarcinoma, Pancreatic Ductal" 24048453 "In the plasma-miRNA population, we find miRNA-375, which is selectively expressed in the endocrine pancreas under normal conditions, increased in PDAC cases compared with patients with other pancreatic or gastrointestinal diseases. The miRNA-375 does not outperform CA-19-9 diagnostically in the present cohort." circulation_biomarker_diagnosis_up hsa-mir-202 Multiple Myeloma 24048721 "The relative expression of serum miR-202 in MM patients was significantly higher than that in healthy controls, and therefore it may prove to be useful in the auxiliary diagnosis of MM." circulation_biomarker_diagnosis_up hsa-mir-146a Rheumatoid Arthritis 24120842 "Elevated expression of specific microRNAs (miRNA) in peripheral blood-derived mononuclear cells (PBMC), particularly miR-146a and miR-155, is associated with rheumatoid arthritis (RA)." circulation_biomarker_diagnosis_up hsa-mir-155 Rheumatoid Arthritis 24120842 "Elevated expression of specific microRNAs (miRNA) in peripheral blood-derived mononuclear cells (PBMC), particularly miR-146a and miR-155, is associated with rheumatoid arthritis (RA)." circulation_biomarker_diagnosis_up hsa-mir-369 Psoriasis 24135466 "The expression of miR-369-3p is increased in both serum samples and skin tissues from psoriasis patients, and its level in the skin positively correlates with disease severity. Further studies are needed to clarify the role of miR-369-3p in the pathogenesis of psoriasis." circulation_biomarker_diagnosis_up hsa-mir-29a "Cardiomyopathy, Hypertrophic" 24161319 "cardiac remodeling associated with HCM determines a significant release of miRNAs into the bloodstream: the circulating levels of both cardiac- and non-cardiac-specific miRNAs are significantly increased in the plasma of HCM patients. However, correlation with left ventricular hypertrophy parameters holds true for only a few miRNAs (i.e.,miR-199a-5p, -27a, and -29a), whereas only miR-29a is significantly associated with both hypertrophy and fibrosis, identifying it as a potential biomarker for myocardial remodeling assessment in HCM." circulation_biomarker_diagnosis_up hsa-mir-155 "Adenocarcinoma, Lung" 24190459 endogenous miR-155 stably existed in patient serum and could be sensitively and specifically measured. Overexpression of miR-155 in serum specimens could constitute a diagnostic marker for the early detection of lung adenocarcinoma. circulation_biomarker_diagnosis_up hsa-mir-208a Acute Myocardial Infarction 24253456 Early in acute myocardial infarction the expression of miR-423-5p in plasma is significantly increased with subsequent normalization within 6 hours.Potentially it is an early marker of myocardial necrosis. circulation_biomarker_diagnosis_up hsa-mir-423 Acute Myocardial Infarction 24253456 Early in acute myocardial infarction the expression of miR-423-5p in plasma is significantly increased with subsequent normalization within 6 hours.Potentially it is an early marker of myocardial necrosis. circulation_biomarker_diagnosis_up hsa-mir-200c Kawasaki Syndrome 24259014 Elevated serum level of microRNA (miRNA)-200c and miRNA-371-5p in children with Kawasaki disease. circulation_biomarker_diagnosis_up hsa-mir-371 Kawasaki Syndrome 24259014 Elevated serum level of microRNA (miRNA)-200c and miRNA-371-5p in children with Kawasaki disease. circulation_biomarker_diagnosis_up hsa-mir-1 Essential Hypertension 24284386 "Hypertensive patients showed lower miR-143, miR-145 and miR-133 and higher miR-21 and miR-1 expression levels compared with controls" circulation_biomarker_diagnosis_up hsa-mir-185 Idiopathic Short Stature 24342208 plasma miR-185 expression was significantly up-regulated circulation_biomarker_diagnosis_up hsa-mir-208a Myocardial Infarction 24482699 Serum miR-208a was increased by 36-fold and 51-fold while miR-499 was elevated by 103-fold and 95-fold at 4 h and 24 h after AMI. circulation_biomarker_diagnosis_up hsa-mir-499 Myocardial Infarction 24482699 Serum miR-208a was increased by 36-fold and 51-fold while miR-499 was elevated by 103-fold and 95-fold at 4 h and 24 h after AMI. circulation_biomarker_diagnosis_up hsa-mir-22 Graves Disease 24533739 "Further analysis consistently showed that serum levels of miR-22, miR-375 and miR-451 were increased in patients with HT. On the other hand, the serum levels of miR-16, miR-22, miR-375 and miR-451 were increased in patients with GD compared with healthy subjects." circulation_biomarker_diagnosis_up hsa-mir-192 Ischemia-Reperfusion Injury 24553149 "However, miR-10a, miR-192, and miR-194 were significantly increased in plasma of rats with renal ischemia-reperfusion injury, among which miR-10a was elevated within 1 h after reperfusion, whereas miR-192 and miR-194 were elevated at 6 h after injury." circulation_biomarker_diagnosis_up hsa-mir-194 Ischemia-Reperfusion Injury 24553149 "However, miR-10a, miR-192, and miR-194 were significantly increased in plasma of rats with renal ischemia-reperfusion injury, among which miR-10a was elevated within 1 h after reperfusion, whereas miR-192 and miR-194 were elevated at 6 h after injury." circulation_biomarker_diagnosis_up hsa-mir-21 Chronic Obstructive Pulmonary Disease 24556821 An increased ratio of serum miR-21 to miR-181a levels is associated with the early pathogenic process of chronic obstructive pulmonary disease in asymptomatic heavy smokers. circulation_biomarker_diagnosis_up hsa-mir-29a Ankylosing Spondylitis 24593209 "We report for the first time elevated miR-29a expression in PBMCs of patients with ankylosing spondylitis, and miR-29a might be used as a useful diagnostic marker in new bone formation but cannot reflect disease activity." circulation_biomarker_diagnosis_up hsa-mir-204 Kidney Injury 24641951 Our findings indicate that miR-204/miR-211 downregulation accounts at least partially for the Hmx1 upregulation and the miR-204/miR-211-Hmx1 signaling axis may contribute to immune-suppression in the host thereby the Candidemia-induced kidney dysfunction. circulation_biomarker_diagnosis_up hsa-mir-211 Kidney Injury 24641951 Our findings indicate that miR-204/miR-211 downregulation accounts at least partially for the Hmx1 upregulation and the miR-204/miR-211-Hmx1 signaling axis may contribute to immune-suppression in the host thereby the Candidemia-induced kidney dysfunction. circulation_biomarker_diagnosis_up hsa-mir-100 "Squamous Cell Carcinoma, Esophageal" 24651474 "Seven serum miRNAs were found to be significantly higher in ESCC than in controls; namely, miR-25, miR-100, miR-193-3p, miR-194, miR-223, miR-337-5p and miR-483-5p" circulation_biomarker_diagnosis_up hsa-mir-193 "Squamous Cell Carcinoma, Esophageal" 24651474 "Seven serum miRNAs were found to be significantly higher in ESCC than in controls; namely, miR-25, miR-100, miR-193-3p, miR-194, miR-223, miR-337-5p and miR-483-5p" circulation_biomarker_diagnosis_up hsa-mir-194 "Squamous Cell Carcinoma, Esophageal" 24651474 "Seven serum miRNAs were found to be significantly higher in ESCC than in controls; namely, miR-25, miR-100, miR-193-3p, miR-194, miR-223, miR-337-5p and miR-483-5p" circulation_biomarker_diagnosis_up hsa-mir-223 "Squamous Cell Carcinoma, Esophageal" 24651474 "Seven serum miRNAs were found to be significantly higher in ESCC than in controls; namely, miR-25, miR-100, miR-193-3p, miR-194, miR-223, miR-337-5p and miR-483-5p" circulation_biomarker_diagnosis_up hsa-mir-25 "Squamous Cell Carcinoma, Esophageal" 24651474 "Seven serum miRNAs were found to be significantly higher in ESCC than in controls; namely, miR-25, miR-100, miR-193-3p, miR-194, miR-223, miR-337-5p and miR-483-5p" circulation_biomarker_diagnosis_up hsa-mir-337 "Squamous Cell Carcinoma, Esophageal" 24651474 "Seven serum miRNAs were found to be significantly higher in ESCC than in controls; namely, miR-25, miR-100, miR-193-3p, miR-194, miR-223, miR-337-5p and miR-483-5p" circulation_biomarker_diagnosis_up hsa-mir-483 "Squamous Cell Carcinoma, Esophageal" 24651474 "Seven serum miRNAs were found to be significantly higher in ESCC than in controls; namely, miR-25, miR-100, miR-193-3p, miR-194, miR-223, miR-337-5p and miR-483-5p" circulation_biomarker_diagnosis_up hsa-mir-21 Systemic Lupus Erythematosus 24659142 "Plasma miR-21 in SLE patients from Central China is overexpressed.Since circulating miR-21 is aberrantly expressed in many diseases, the applying of it as a disease biomarker should be considered carefully." circulation_biomarker_diagnosis_up hsa-mir-146a Sepsis 24680405 "The expression levels of miR-146a and miR-223 in plasma in pediatric patients with sepsis was significantly upregulated, and had a positive correlation with IL-10 and IL-10/TNF-¦Á, which may be used as early diagnostic markers and can reflect the severity of condition to a certain degree." circulation_biomarker_diagnosis_up hsa-mir-223 Sepsis 24680405 "The expression levels of miR-146a and miR-223 in plasma in pediatric patients with sepsis was significantly upregulated, and had a positive correlation with IL-10 and IL-10/TNF-¦Á, which may be used as early diagnostic markers and can reflect the severity of condition to a certain degree." circulation_biomarker_diagnosis_up hsa-mir-516a "Systemic Lupus Erythematosus, With Pericarditis" 24687380 "High expression levels of microRNA-629, microRNA-525-5p and microRNA-516a-3p in paediatric systemic lupus erythematosus." circulation_biomarker_diagnosis_up hsa-mir-525 "Systemic Lupus Erythematosus, With Pericarditis" 24687380 "High expression levels of microRNA-629, microRNA-525-5p and microRNA-516a-3p in paediatric systemic lupus erythematosus." circulation_biomarker_diagnosis_up hsa-mir-629 "Systemic Lupus Erythematosus, With Pericarditis" 24687380 "High expression levels of microRNA-629, microRNA-525-5p and microRNA-516a-3p in paediatric systemic lupus erythematosus." circulation_biomarker_diagnosis_up hsa-mir-193b Pancreatic Endocrine Carcinoma 24778027 "Evaluation of microRNAs appears to be promising in the assessment of pNEN. In particular, miR-193b, which is also increased in serum, may be a potential new biomarker of pNEN." circulation_biomarker_diagnosis_up hsa-mir-21 Ankylosing Spondylitis 24786924 Higher expression of whole blood microRNA-21 in patients with ankylosing spondylitis associated with programmed cell death 4 mRNA expression and collagen cross-linked C-telopeptide concentration. circulation_biomarker_diagnosis_up hsa-mir-21 Atherosclerosis 24848278 "In atherosclerosis, miR-21, 122, 130a, and 211 were significantly increased whereas miR-92a, 126, and 222 were markedly decreased." circulation_biomarker_diagnosis_up hsa-mir-143 "Diabetes Mellitus, Type 2" 24927876 Elevated expression levels of miR-143/5 in saphenous vein smooth muscle cells from patients with Type 2 diabetes drive persistent changes in phenotype and function. circulation_biomarker_diagnosis_up hsa-mir-145 "Diabetes Mellitus, Type 2" 24927876 Elevated expression levels of miR-143/5 in saphenous vein smooth muscle cells from patients with Type 2 diabetes drive persistent changes in phenotype and function. circulation_biomarker_diagnosis_up hsa-mir-146a Sjogren Syndrome 24931100 "Our results demonstrated miR-146a overexpression and miR-155 underexpression in the peripheral mononuclear blood cells of the patients with pSS. Furthermore, the expression levels of these miRNAs correlated with the patients' clinical features. Our data suggest that miR-146a and miR-155 might play important roles in the pathogenesis of pSS and that their expression levels may be useful for diagnosing pSS and for predicting disease activity and therapeutic responses." circulation_biomarker_diagnosis_up hsa-mir-196a Pancreatic Neoplasms 24956938 Serum levels of miR-196a and -196b were significantly higher in mice with PanIN2/3 lesions (n = 10) or PC (n = 8) as compared to control mice (n = 10) or mice with PanIN1 lesions (n = 10; P = .01). circulation_biomarker_diagnosis_up hsa-mir-130a Moyamoya Disease 25093848 "In an independent MMD cohort, real-time PCR confirmed that miR-106b, miR-130a and miR-126 were significantly upregulated while miR-125a-3p was significantly downregulated in serum." circulation_biomarker_diagnosis_up hsa-mir-21 Neoplasms [unspecific] 25098165 "Over-expression of mir-21, especially in cancerous tissue, was effectively predictive of worse prognosis in various carcinomas. Non-invasive circulating mir-21, however, exhibited modest ability to discriminate outcomes.Major concerns about mir-21 assay standardization and selection of specimen need to be fully addressed before its practical implementation in management of cancer." circulation_biomarker_diagnosis_up hsa-mir-323 Acute Coronary Syndrome 25124998 Our study identifies miR-652 as a novel candidate biomarker for post-ACS prognosis beyond existing biomarkers of LVEF and NT-proBNP. Moreover circulating miR-323-3p was markedly elevated in patients for at least a year post-ACS and may be a stable biomarker for ACS. circulation_biomarker_diagnosis_up hsa-mir-652 Acute Coronary Syndrome 25124998 Our study identifies miR-652 as a novel candidate biomarker for post-ACS prognosis beyond existing biomarkers of LVEF and NT-proBNP. Moreover circulating miR-323-3p was markedly elevated in patients for at least a year post-ACS and may be a stable biomarker for ACS. circulation_biomarker_diagnosis_up hsa-mir-181a Sjogren Syndrome 25128511 "Together, these observations suggested that an elevated miRNA-181a level is a general phenomenon in Chinese patients with pSS." circulation_biomarker_diagnosis_up hsa-mir-338 Amyotrophic Lateral Sclerosis 25130371 "miR-338-3p is over-expressed in blood, CFS, serum and spinal cord from sporadic amyotrophic lateral sclerosis patients." circulation_biomarker_diagnosis_up hsa-mir-21 Colorectal Carcinoma 25178939 Elevated level of microRNA-21 in the serum of patients with colorectal cancer. circulation_biomarker_diagnosis_up hsa-mir-1 Myocardial Infarction 25225581 the expression of plasma miR-1 was significantly increased in the AMI patients compared with the healthy controls circulation_biomarker_diagnosis_up hsa-mir-92a "Lymphoma, Non-Hodgkin" 25236768 "MiR-92a was decreased exclusively in HBV-/HCV- B-NHLs, while miR-30b was increased in HBV+ and HCV+ samples, though only the HCV+ achieved full statistical significance." circulation_biomarker_diagnosis_up hsa-mir-205 Pancreatic Neoplasms 25258651 "A marked difference in the profiles of four circulating miRNAs (miR-205, miR-210, miR-492, and miR-1427) was observed in pancreatic juice collected from patients with PDAC and those without pancreatic disease." circulation_biomarker_diagnosis_up hsa-mir-210 Pancreatic Neoplasms 25258651 "A marked difference in the profiles of four circulating miRNAs (miR-205, miR-210, miR-492, and miR-1427) was observed in pancreatic juice collected from patients with PDAC and those without pancreatic disease." circulation_biomarker_diagnosis_up hsa-mir-373 Breast Neoplasms 25333260 Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients. circulation_biomarker_diagnosis_up hsa-mir-195 Heart Failure 25364765 "Circulating miR-195 is elevated in acute myocardial infarction, breast cancer, prostate cancer and colorectal adenoma." circulation_biomarker_diagnosis_up hsa-mir-21 Pancreatic Neoplasms 25384963 Circulating miR-483-3p and miR-21 is highly expressed in plasma of pancreatic cancer. circulation_biomarker_diagnosis_up hsa-mir-483 Pancreatic Neoplasms 25384963 Circulating miR-483-3p and miR-21 is highly expressed in plasma of pancreatic cancer. circulation_biomarker_diagnosis_up hsa-mir-221 Hepatitis C Virus Infection 25433287 HCVcc infection could upregulate the expression of miR-221 in NF-¦ÊB dependent manner. circulation_biomarker_diagnosis_up hsa-mir-122 Chronic Hepatitis C 25461662 "serum microRNA-122 was elevated in acute and chronic hepatitis patients. However, this biomarker for acute liver injury did not reflect the liver inflammation activity in CHC patients." circulation_biomarker_diagnosis_up hsa-mir-421 Gastric Neoplasms 25510566 miR-421 increased significantly in GC patients than in controls. miR-421 in either serum or PBMCs had higher sensitivity and specificity than CEA and CA-125 in GC diagnosis. circulation_biomarker_diagnosis_up hsa-mir-203 Atopic Dermatitis 25531302 miR-203 and miR-483-5p were significantly up-regulated in serum of children with AD compared with healthy children. circulation_biomarker_diagnosis_up hsa-mir-132 Mild Cognitive Impairment 25589731 circulating miR-206 and miR-132 as novel miRNAs upregulated in MCI patient were potential biomarkers for diagnosis of MCI. circulation_biomarker_diagnosis_up hsa-mir-206 Mild Cognitive Impairment 25589731 circulating miR-206 and miR-132 as novel miRNAs upregulated in MCI patient were potential biomarkers for diagnosis of MCI. circulation_biomarker_diagnosis_up hsa-mir-133 Arrhythmia 25625292 patients with SVT had lower miR-1 expression levels while those with VT had higher miR-133 expression levels. circulation_biomarker_diagnosis_up hsa-mir-182 Heart Failure 25643195 "Microarray profiling revealed an increase in the expression of miR-21, miR-650, miR-744, miR-516-5p, miR-1292, miR-182, miR-1228, miR-595, miR-663b, miR-1296, miR-1825, miR-299-3p, miR-662 miR-122, miR-3148 and miR-518e and a decrease in the expression of miR-129-3p, miR-3155, miR-3175, miR-583, miR-568, miR-30d, miR-200a-star, miR-1979, miR-371-3p, miR-155-star and miR-502-5p in sera of CHF patients." circulation_biomarker_diagnosis_up hsa-mir-299 Heart Failure 25643195 "Microarray profiling revealed an increase in the expression of miR-21, miR-650, miR-744, miR-516-5p, miR-1292, miR-182, miR-1228, miR-595, miR-663b, miR-1296, miR-1825, miR-299-3p, miR-662 miR-122, miR-3148 and miR-518e and a decrease in the expression of miR-129-3p, miR-3155, miR-3175, miR-583, miR-568, miR-30d, miR-200a-star, miR-1979, miR-371-3p, miR-155-star and miR-502-5p in sera of CHF patients." circulation_biomarker_diagnosis_up hsa-mir-197 Breast Neoplasms 25644077 "The expression level of miR-29b-2, -155, -197 and -205 was significantly increased in the serum of breast cancer patients." circulation_biomarker_diagnosis_up hsa-mir-10a "Leukemia, Myeloid, Acute" 25687041 "The high expression of miR-10a may be closely related to over-proliferation of promyelocyte and drug resistance of acute myeloid leukemia cells, except M3." circulation_biomarker_diagnosis_up hsa-mir-126 Atherosclerosis 25697638 and the levels of miR-126 had positive correlation with cerebral atherosclerosis circulation_biomarker_diagnosis_up hsa-mir-17 Atherosclerosis 25697638 he levels of miR-17 were significantly increased in acute stroke patients circulation_biomarker_diagnosis_up hsa-mir-101 "Diabetes Mellitus, Type 2" 25726255 "The present findings demonstrated that the circulating miR-101, miR-375 and miR-802 levels are significantly increased in T2D patients versus NGT subjects and they may become the new biomarkers for type 2 diabetes." circulation_biomarker_diagnosis_up hsa-mir-375 "Diabetes Mellitus, Type 2" 25726255 "The present findings demonstrated that the circulating miR-101, miR-375 and miR-802 levels are significantly increased in T2D patients versus NGT subjects and they may become the new biomarkers for type 2 diabetes." circulation_biomarker_diagnosis_up hsa-mir-802 "Diabetes Mellitus, Type 2" 25726255 "The present findings demonstrated that the circulating miR-101, miR-375 and miR-802 levels are significantly increased in T2D patients versus NGT subjects and they may become the new biomarkers for type 2 diabetes." circulation_biomarker_diagnosis_up hsa-mir-29a Colorectal Carcinoma 25736690 Significant upregulation of miR-29a in CRC was reported when compared to normal circulation_biomarker_diagnosis_up hsa-mir-146a Oral Lichen Planus 25779071 The expressions of PBMC and plasma miRNA-155 and miRNA-146a are higher in OLP patients. The expressions of plasma miRNA-155 and miRNA-146a are associated with OLP severity. The over expression of miRNA-155 and miRNA-146a in OLP may play a role in the pathogenesis of OLP. circulation_biomarker_diagnosis_up hsa-mir-155 Oral Lichen Planus 25779071 The expressions of PBMC and plasma miRNA-155 and miRNA-146a are higher in OLP patients. The expressions of plasma miRNA-155 and miRNA-146a are associated with OLP severity. The over expression of miRNA-155 and miRNA-146a in OLP may play a role in the pathogenesis of OLP. circulation_biomarker_diagnosis_up hsa-mir-184 Oral Neoplasms 25784212 There was a highly significant increase in salivary miRNA-21 and miRNA-184 in OSCC and PMD circulation_biomarker_diagnosis_up hsa-mir-296 Chronic Hepatitis C 25790297 "Serum miR-34a, miR-130a, miR-19a, miR-192, miR-195, and miR-296 were upregulated, whereas serum miR-146a was downregulated in CHC compared to controls." circulation_biomarker_diagnosis_up hsa-mir-122 Hypertension 25837765 MiR-122 and miR-637 expressions were also significantly upregulated in the WCH group compared with the NT group circulation_biomarker_diagnosis_up hsa-mir-10b "Carcinoma, Lung, Non-Small-Cell" 25869877 Prognostic value of microRNA-10b overexpression in peripheral blood mononuclear cells of nonsmall-cell lung cancer patients. circulation_biomarker_diagnosis_up hsa-mir-192 Pancreatic Neoplasms 25894267 "Our data shows that miR-21, miR-192 and miR-200 could be used as new diagnostic markers for pancreatic cancer." circulation_biomarker_diagnosis_up hsa-mir-200 Pancreatic Neoplasms 25894267 "Our data shows that miR-21, miR-192 and miR-200 could be used as new diagnostic markers for pancreatic cancer." circulation_biomarker_diagnosis_up hsa-mir-21 Pancreatic Neoplasms 25894267 "Our data shows that miR-21, miR-192 and miR-200 could be used as new diagnostic markers for pancreatic cancer." circulation_biomarker_diagnosis_up hsa-mir-182 "Carcinoma, Hepatocellular" 25903466 "our present study indicates that serum miR-182 and miR-331-3p, upregulated in HCC, can provide positive diagnostic and prognostic values for HCC" circulation_biomarker_diagnosis_up hsa-mir-331 "Carcinoma, Hepatocellular" 25903466 Serum miR-182 and miR-331-3p as diagnostic and prognostic markers in patients with hepatocellular carcinoma. circulation_biomarker_diagnosis_up hsa-mir-499 Myocardial Infarction 25922707 miR-499 was shown to substantially increase the diagnostic accuracy of CK-MB and cTnI in the diagnosis of AMI circulation_biomarker_diagnosis_up hsa-mir-451 Mountain Sickness 25948209 "There is a certain level of microRNA-451 in healthy people, the expression of microRNA-451 in CMS patients is significantly higher than that in healthy people. MicroRNA-451 may play an important role in the process of chronic mountain sickness." circulation_biomarker_diagnosis_up hsa-mir-499 Myocardial Infarction 25966174 the expression of microRNA-499 in serum of patients with AMI was significantly higher than in controls circulation_biomarker_diagnosis_up hsa-mir-25 Pancreatic Neoplasms 25991015 "A combination of six serum miRNAs (miR-483-5p, miR-19a, miR-29a, miR-20a, miR-24, miR-25) was selected by qRT-PCR as a biomarker for PaC-DM." circulation_biomarker_diagnosis_up hsa-mir-499 Acute Myocardial Infarction 26101645 miR-499 expression levels were significantly higher in the 53 AMI patients circulation_biomarker_diagnosis_up hsa-mir-122 Hepatitis C Virus Infection 26157120 "During acute HCV infection, increases in miR-122 (P < 0.01) and miR-885-5p (Pcorrected < 0.05) and a decrease in miR-494 (Pcorrected < 0.05) were observed at the earliest time points after virus detection." circulation_biomarker_diagnosis_up hsa-mir-223 Rheumatoid Arthritis 26164649 "MiR-16, miR-146a/b, miR-150, miR-155, and miR-223 described here were shown to be overexpressed at the systemic level: in both the periphery and RA joints." circulation_biomarker_diagnosis_up hsa-mir-200a Cervical Neoplasms 26171195 The Solexa sequencing results revealed 12 markedly upregulated serum miRNAs in cervical cancer patients compared with controls circulation_biomarker_diagnosis_up hsa-mir-146b Schizophrenia 26173148 "a nominally significant increase in the expression of several miRNAs was found in the 22q11.2 neurons that were previously found to be differentially expressed in autopsy samples and peripheral blood in SZ and autism spectrum disorders (e.g.,miR-34, miR-4449, miR-146b-3p, and miR-23a-5p)." circulation_biomarker_diagnosis_up hsa-mir-23a Schizophrenia 26173148 "a nominally significant increase in the expression of several miRNAs was found in the 22q11.2 neurons that were previously found to be differentially expressed in autopsy samples and peripheral blood in SZ and autism spectrum disorders (e.g.,miR-34, miR-4449, miR-146b-3p, and miR-23a-5p)." circulation_biomarker_diagnosis_up hsa-mir-34 Schizophrenia 26173148 "a nominally significant increase in the expression of several miRNAs was found in the 22q11.2 neurons that were previously found to be differentially expressed in autopsy samples and peripheral blood in SZ and autism spectrum disorders (e.g.,miR-34, miR-4449, miR-146b-3p, and miR-23a-5p)." circulation_biomarker_diagnosis_up hsa-mir-4449 Schizophrenia 26173148 "a nominally significant increase in the expression of several miRNAs was found in the 22q11.2 neurons that were previously found to be differentially expressed in autopsy samples and peripheral blood in SZ and autism spectrum disorders (e.g.,miR-34, miR-4449, miR-146b-3p, and miR-23a-5p)." circulation_biomarker_diagnosis_up hsa-mir-144 "Stroke, Ischemic" 26175178 "In conclusion, hyperglycemia may activate platelets through miR-144 and miR-223 to downregulate IRS-1 and upregulate P2Y12 expression in the platelets of T2DM patients through an IRS-1-PI3K-Akt signaling." circulation_biomarker_diagnosis_up hsa-mir-223 "Stroke, Ischemic" 26175178 "In conclusion, hyperglycemia may activate platelets through miR-144 and miR-223 to downregulate IRS-1 and upregulate P2Y12 expression in the platelets of T2DM patients through an IRS-1-PI3K-Akt signaling." circulation_biomarker_diagnosis_up hsa-mir-130b Schizophrenia 26183697 "The up-regulation of miR-130b and miR-193a-3p is a state-independent biomarker for schizophrenia, and these two miRNAs could be used to develop a diagnostic tool for schizophrenia." circulation_biomarker_diagnosis_up hsa-mir-193a Schizophrenia 26183697 "The up-regulation of miR-130b and miR-193a-3p is a state-independent biomarker for schizophrenia, and these two miRNAs could be used to develop a diagnostic tool for schizophrenia." circulation_biomarker_diagnosis_up hsa-mir-92a-2 Cardiac Allograft Vasculopathy 26198441 "Median plasma levels of miR-210-5p, miR-92a-3p, miR-126-3p, and miR-126-5p were higher in patients with CAV than in patients without CAV." circulation_biomarker_diagnosis_up hsa-mir-133b Myocardial Infarction 26198874 "The level of miR-133a, miR-133b and miR-499-5p were significantly higher in both STEMI and NSTEMI patients compared to healthy volunteers" circulation_biomarker_diagnosis_up hsa-mir-16 "Squamous Cell Carcinoma, Esophageal" 26221263 "Levels of four of the selected miRNAs were found to be significantly higher in ESCC patients than in controls; namely, miR-16, miR-21, miR-185, and miR-375 (P < 0.050)." circulation_biomarker_diagnosis_up hsa-mir-370 Obesity 26223376 "circulating miR-27 (Pâ€?â€?.032), miR-378 (Pâ€?â€?.001) and miR-370 (Pâ€?â€?.045) in obese children were significantly higher" circulation_biomarker_diagnosis_up hsa-mir-378 Obesity 26223376 "circulating miR-27 (Pâ€?â€?.032), miR-378 (Pâ€?â€?.001) and miR-370 (Pâ€?â€?.045) in obese children were significantly higher" circulation_biomarker_diagnosis_up hsa-mir-33a Hypercholesterolaemia 26229086 Circulating miR-33a and miR-33b are up-regulated in familial hypercholesterolaemia in paediatric age. circulation_biomarker_diagnosis_up hsa-mir-33b Hypercholesterolaemia 26229086 Circulating miR-33a and miR-33b are up-regulated in familial hypercholesterolaemia in paediatric age. circulation_biomarker_diagnosis_up hsa-mir-21 Coronary Artery Disease 26248417 "miRNA-21 was significantly elevated in acute myocardial infarction subgroup than the control group. The level of miRNA-21 associates with the degree of coronary artery stenosis, and might be a potential marker for the diagnosis of acute myocardial infarction. miRNA-21 may play an important role in protecting myocardium from ischemia/reperfusion injury." circulation_biomarker_diagnosis_up hsa-mir-223 Tuberculosis 26316141 "Leukocyte recruitment, measured as the expression of microRNA-223 was increased in pulmonary TB patients compared to LTBI" circulation_biomarker_diagnosis_up hsa-mir-301a Autoimmune Diseases [unspecific] 26338824 Our data reveal a novel mechanism in which the elevated miR-301a in PBMC and inflamed mucosa of IBD promotes Th17 cell differentiation through downregulation of SNIP1. circulation_biomarker_diagnosis_up hsa-mir-222 "Carcinoma, Hepatocellular" 26380927 "The serum levels of exosomal miR-18a, miR-221, miR-222 and miR-224 were significantly higher in patients with HCC" circulation_biomarker_diagnosis_up hsa-mir-27b Diabetic Retinopathy 26395742 "miR-27b and miR-320a, were associated with incidence and with progression of retinopathy" circulation_biomarker_diagnosis_up hsa-mir-107 Gastric Neoplasms 26406411 The overexpression of miR-107 in tumors and serum of gastric cancer patients and its correlation with HIF-1¦Á expression in tumor tissues was indicated that miR-107 may have a potential to use as a biomarker for detection of gastric cancer patients and hypoxia in gastric cancer tumor. circulation_biomarker_diagnosis_up hsa-mir-191 Osteosarcoma 26406942 "Our data provide new insights for the involvement of miR-191 in osteosarcoma and suggest that the increased expression of miR-191 may be associated with aggressive tumor progression and adverse outcome. Of note, serum miR-191 quantification may be a promising biomarker for the diagnosis and prognosis in osteosarcoma." circulation_biomarker_diagnosis_up hsa-mir-200b "Carcinoma, Ovarian" 26416421 Plasma miR-200b proved to have a greater average concentration in OvCa samples circulation_biomarker_diagnosis_up hsa-mir-15a "Leukemia, Lymphoblastic, Acute" 26434860 "The results of our study indicate that resveratrol induces apoptosis in a time and dose-dependent manner in CCRF-CEM cells. Also, increased expression level of miR 16-1 and miR 15a by means of resveratrol in CCRF-CEM" circulation_biomarker_diagnosis_up hsa-mir-16-1 "Leukemia, Lymphoblastic, Acute" 26434860 "The results of our study indicate that resveratrol induces apoptosis in a time and dose- dependent manner in CCRF-CEM cells. Also, increased expression level of miR 16-1 and miR 15a by means of resveratrol in CCRF-CEM" circulation_biomarker_diagnosis_up hsa-mir-192 Cholangiocarcinoma 26456596 "We found that miR-192 was significantly higher in O. viverrini infected, PDF and also CCA groups (p<0.05) than in healthy controls." circulation_biomarker_diagnosis_up hsa-mir-21 Cholangiocarcinoma 26456596 MiR-21 was significantly higher in PDF and CCA groups (p<0.05) than in healthy controls. circulation_biomarker_diagnosis_up hsa-mir-18a "Leukemia, Myeloid, Chronic" 26458312 "up-regulated expression of oncogenic miRNAs (miR-17, miR-18a, miR-20a, miR-21, miR-27a and miR-155)" circulation_biomarker_diagnosis_up hsa-mir-184 Neoplasms [unspecific] 26525105 "The increase of plasma miR-146a, miR-184 and miR-372 was detectable early in the induction, and it was particularly eminent at the most advanced lesion state." circulation_biomarker_diagnosis_up hsa-mir-31 Neoplasms [unspecific] 26525105 "A progressive increase of miR-21, miR-31 and miR-146a in both saliva and plasma samples was also noted." circulation_biomarker_diagnosis_up hsa-mir-372 Neoplasms [unspecific] 26525105 "The increase of plasma miR-146a, miR-184 and miR-372 was detectable early in the induction" circulation_biomarker_diagnosis_up hsa-mir-208a Myocardial Infarction 26528525 miRNA-208a was increased in STEMI patients at the time of admission and nearly undetectable in CAD patients and controls. circulation_biomarker_diagnosis_up hsa-mir-210 "Leukemia, Myeloid, Acute" 26549593 MiR-210 up-regulation was associated with poor prognosis in AML and it might be useful as a marker for predicting the clinical outcome of AML patients. circulation_biomarker_diagnosis_up hsa-mir-423 Cardiovascular Diseases [unspecific] 26562412 "Our results suggested that miR-423-5p is enriched in PF, and serum miR-423-5p may be associate with uAP. Its expression pattern was different to that of muscle- and vascular-enriched miRNAs, miR-133a, miR-126, and miR-92a." circulation_biomarker_diagnosis_up hsa-mir-223 Polycystic Ovarian Syndrome 26582398 "In conclusion, circulating miRNA-93 and miRNA-223 were higher in women with PCOS compared to age and weight matched controls independent of insulin resistance and testosterone levels, and miR-93 may represent a novel diagnostic biomarker for PCOS." circulation_biomarker_diagnosis_up hsa-mir-93 Polycystic Ovarian Syndrome 26582398 "In conclusion, circulating miRNA-93 and miRNA-223 were higher in women with PCOS compared to age and weight matched controls independent of insulin resistance and testosterone levels, and miR-93 may represent a novel diagnostic biomarker for PCOS." circulation_biomarker_diagnosis_up hsa-mir-208 Cardiomegaly 26622415 miR-208 expression levels are increased in the peripheral blood of patients with cardiac hypertrophy. circulation_biomarker_diagnosis_up hsa-mir-195 Parkinson Disease 26631952 "miR-195 was up-regulated, and miR-185, miR-15b, miR-221 and miR-181a were down-regulated." circulation_biomarker_diagnosis_up hsa-mir-206 Coronary Artery Disease 26685009 miRNA 206 and miRNA 574-5p are highly expression in coronary artery disease. circulation_biomarker_diagnosis_up hsa-mir-574 Coronary Artery Disease 26685009 miRNA 206 and miRNA 574-5p are highly expression in coronary artery disease. circulation_biomarker_diagnosis_up hsa-mir-196b "Leukemia, Myeloid, Acute" 26744876 The expression level of miR-155 was significantly higher in AML patients than in controls. circulation_biomarker_diagnosis_up hsa-mir-191 Traumatic Brain Injury 26756543 "Elevated serum miR-93, miR-191, and miR-499 are noninvasive biomarkers for the presence and progression of traumatic brain injury." circulation_biomarker_diagnosis_up hsa-mir-499 Traumatic Brain Injury 26756543 "Elevated serum miR-93, miR-191, and miR-499 are noninvasive biomarkers for the presence and progression of traumatic brain injury." circulation_biomarker_diagnosis_up hsa-mir-93 Traumatic Brain Injury 26756543 "Elevated serum miR-93, miR-191, and miR-499 are noninvasive biomarkers for the presence and progression of traumatic brain injury." circulation_biomarker_diagnosis_up hsa-mir-96 "Carcinoma, Hepatocellular" 26770453 Serum miR-96 levels in the HCC patients were remarkably higher than in the other groups circulation_biomarker_diagnosis_up hsa-mir-92a Gastric Neoplasms 26790436 High expression of miR-92a compared with adjacent normal tissues was associated with shorter OS. circulation_biomarker_diagnosis_up hsa-mir-125b Chronic Hepatitis B 26802212 serum miRNA-125b was positively correlated with the serum HBV DNA level. circulation_biomarker_diagnosis_up hsa-mir-143 Pancreatic Adenocarcinoma 26807325 "Three miRNAs (miR-143, miR-223, and miR-30e) were significantly over-expressed in patients with Stage I cancer when compared with age-matched healthy individuals" circulation_biomarker_diagnosis_up hsa-mir-223 Choriocarcinoma 26807325 "Three miRNAs (miR-143, miR-223, and miR-30e) were significantly over-expressed in patients with Stage I cancer when compared with age-matched healthy individuals" circulation_biomarker_diagnosis_up hsa-mir-122 Chronic Hepatitis C 26812693 serum levels of miR-122 and miR-222 were significantly elevated in HCV patients circulation_biomarker_diagnosis_up hsa-mir-222 Chronic Hepatitis C 26812693 the serum levels of miR-122 and miR-222 were significantly elevated in HCV patients circulation_biomarker_diagnosis_up hsa-mir-21 Breast Neoplasms 26827795 the serum levels of miR-21 and miR-221 were significantly overexpressed in breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-221 Breast Neoplasms 26827795 the serum levels of miR-21 and miR-221 were significantly overexpressed in breast cancer patients circulation_biomarker_diagnosis_up hsa-mir-885 Preeclampsia 26853698 "miR-885-5p is increased in plasma from pre-eclampsia compared with healthy pregnant women, and it is released into circulation mainly inside exosomes." circulation_biomarker_diagnosis_up hsa-mir-122 Polycystic Ovarian Syndrome 26860517 "relative expression of miR-122, miR-193b, and miR-194 was up-regulated in PCOS patients" circulation_biomarker_diagnosis_up hsa-mir-193b Polycystic Ovarian Syndrome 26860517 "relative expression of miR-122, miR-193b, and miR-194 was up-regulated in PCOS patients" circulation_biomarker_diagnosis_up hsa-mir-194 Polycystic Ovarian Syndrome 26860517 "relative expression of miR-122, miR-193b, and miR-194 was up-regulated in PCOS patients" circulation_biomarker_diagnosis_up hsa-mir-155 Lung Neoplasms 26867772 "Two miRNAs, miR-21 and miR-155, were found to be significantly upregulated in recurrent tumors compared to primary tumors." circulation_biomarker_diagnosis_up hsa-mir-21 Lung Neoplasms 26867772 "Two miRNAs, miR-21 and miR-155, were found to be significantly upregulated in recurrent tumors compared to primary tumors." circulation_biomarker_diagnosis_up hsa-mir-21 Multiple Myeloma 26909911 We found that the expression level of serum mir-21 in the MM group was significantly higher than the MGUS group and the NC group circulation_biomarker_diagnosis_up hsa-let-7 Myasthenia Gravis 26943954 Disease specific enrichment of circulating let-7 family microRNA in MuSK+ myasthenia gravis. circulation_biomarker_diagnosis_up hsa-mir-99b Chronic Fatigue Syndrome 26967895 "Microarray analysis identified differential expression of 34 miRNA, all of which were up-regulated." circulation_biomarker_diagnosis_up hsa-mir-182 Glioma 26978735 Our findings showed that the level of circulating miR-182 in glioma patients was higher than that in healthy controls circulation_biomarker_diagnosis_up hsa-mir-328 Atrial Fibrillation 26987792 Plasma levels of miR-328 were higher in patients with AF than in control subjects. circulation_biomarker_diagnosis_up hsa-mir-96 Colorectal Adenocarcinoma 27044381 miR-96 is significantly upregulated in colorectal adenocarcinoma specimens compared to their non-cancerous counterparts circulation_biomarker_diagnosis_up hsa-mir-15b Glioma 27047250 "we identified significantly increased levels of two candidate biomarkers, miR-15b and miR-21, in blood of patients affected by gliomas" circulation_biomarker_diagnosis_up hsa-mir-16 Glioma 27047250 "we identified significantly increased levels of two candidate biomarkers, miR-15b and miR-21, in blood of patients affected by gliomas" circulation_biomarker_diagnosis_up hsa-mir-21 Glioblastoma 27047250 "we identified significantly increased levels of two candidate biomarkers, miR-15b and miR-21, in blood of patients affected by gliomas" circulation_biomarker_diagnosis_up hsa-mir-21 Glioma 27047250 "we identified significantly increased levels of two candidate biomarkers, miR-15b and miR-21, in blood of patients affected by gliomas" circulation_biomarker_diagnosis_up hsa-mir-21 Autoimmune Lymphoproliferative Syndrome 27060458 "miR-21-3p was over-expressed significantly (P = 0·0313) in the son, with no significant change in the expression of miR-146a, miR-146a-3p and miR-21." circulation_biomarker_diagnosis_up hsa-mir-21 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 27067271 "Compared with controls, miR-21 levels in tissue and plasma were significantly higher for both PLL and LSCC groups" circulation_biomarker_diagnosis_up hsa-mir-124 Depression Disorder 27078210 expression levels of miR-124 from PBMCs in MDD patients were significantly higher than those in healthy controls circulation_biomarker_diagnosis_up hsa-mir-133a Acute Myocardial Infarction 27124025 "circulating miR-133a is upregulated in AMI patients," circulation_biomarker_diagnosis_up hsa-mir-135a Colorectal Carcinoma 27126269 Serum miR-135a-5p expression in colorectal cancer patients was higher than that in patients with colorectal polyps and healthy controls circulation_biomarker_diagnosis_up hsa-mir-30c Aortic Stenosis 27129184 "Levels of miR-30c were higher in the AS group than in the controls (P<0.01), whereas levels of miR-106a, miR-148a, miR-204, miR-211, miR-31 and miR-424 were lower in the AS group than in the controls (P<0.01)." circulation_biomarker_diagnosis_up hsa-mir-4449 Multiple Myeloma 27155004 The expression levels of serum miR-4449 in MM patients were significantly higher than in healthy controls circulation_biomarker_diagnosis_up hsa-mir-499 Acute Myocardial Infarction 27162785 the circulating levels of miRNA-499 was increased in AMI patients. circulation_biomarker_diagnosis_up hsa-mir-499 Heart Failure 27162785 the circulating levels of miRNA-499 was increased in AMI patients. circulation_biomarker_diagnosis_up hsa-mir-21 Glioma 27166186 CSF-based miR-21 might serve as a potential biomarker for diagnosing brain cancer circulation_biomarker_diagnosis_up hsa-mir-125b Myocardial Infarction 27176713 "miR-125b-5p and miR-30d-5p presented a diagnostic value for early diagnosis of AMI, and miRâ€?0dâ€?p may have a higher diagnostic value than cTnI." circulation_biomarker_diagnosis_up hsa-mir-30d Acute Myocardial Infarction 27176713 "miR-125b-5p and miR-30d-5p presented a diagnostic value for early diagnosis of AMI, and miRâ€?0dâ€?p may have a higher diagnostic value than cTnI." circulation_biomarker_diagnosis_up hsa-mir-146a Breast Neoplasms 27197674 "miR-21 (P < 0.001) and miR-146a (P = 0.001) were overexpressed, whereas miR-200c (P = 0.004) and miR-210 (P = 0.002) were underexpressed." circulation_biomarker_diagnosis_up hsa-mir-21 Breast Neoplasms 27197674 "miR-21 (P < 0.001) and miR-146a (P = 0.001) were overexpressed, whereas miR-200c (P = 0.004) and miR-210 (P = 0.002) were underexpressed." circulation_biomarker_diagnosis_up hsa-mir-125a Lupus Nephritis 27215082 "Elevated Serum Inflammatory Cytokines in Lupus Nephritis Patients, in Association with Promoted hsa-miR-125a." circulation_biomarker_diagnosis_up hsa-mir-143 Sepsis 27225861 Serum miR-143 levels were significantly higher in patients with sepsis circulation_biomarker_diagnosis_up hsa-mir-223 Viral Infectious Disease 27226534 vesicular stomatitis virus (VSV) infection induced significant up-regulation of miR-223 in murine macrophages. circulation_biomarker_diagnosis_up hsa-mir-21 Stroke 27288814 The stroke with SAI group had significantly higher miRNA-21 expression circulation_biomarker_diagnosis_up hsa-mir-16 Ischemia-Reperfusion Injury 27297958 urinary miR-16 was 100-fold higher in AKI patients. circulation_biomarker_diagnosis_up hsa-mir-126 "Leukemia, B-Cell" 27300437 miRNA-126 is highly expressed in a subset of human B-ALL circulation_biomarker_diagnosis_up hsa-mir-33b "Diabetes Mellitus, Type 2" 27301461 plasma miRNA33b may be useful as a new metabolic biomarker of dyslipidemia in patients with T2DM circulation_biomarker_diagnosis_up hsa-let-7c Down Syndrome 27323694 "Seven miRNAs were verified as upregulated in DS placentas (miR-99a, miR-542-5p, miR-10b, miR-125b, miR-615, let-7c and miR-654)" circulation_biomarker_diagnosis_up hsa-mir-199a Graft-Versus-Host Disease 27342518 "The expression of miR-423, miR-199a-3p, miR-93* are upregulated in aGVHD group, which can be used as biomarkes to monitor and to diagnose aGVHD." circulation_biomarker_diagnosis_up hsa-mir-423 Graft-Versus-Host Disease 27342518 "The expression of miR-423, miR-199a-3p, miR-93* are upregulated in aGVHD group, which can be used as biomarkes to monitor and to diagnose aGVHD." circulation_biomarker_diagnosis_up hsa-mir-93 Graft-Versus-Host Disease 27342518 "The expression of miR-423, miR-199a-3p, miR-93* are upregulated in aGVHD group, which can be used as biomarkes to monitor and to diagnose aGVHD." circulation_biomarker_diagnosis_up hsa-mir-210 Myocardial Infarction 27346801 miRNA-499 and miRNA-210 expression levels were significantly increased circulation_biomarker_diagnosis_up hsa-mir-499 Acute Coronary Syndrome 27346801 miRNA-499 and miRNA-210 expression levels were significantly increased circulation_biomarker_diagnosis_up hsa-mir-499 Myocardial Infarction 27346801 miRNA-499 and miRNA-210 expression levels were significantly increased circulation_biomarker_diagnosis_up hsa-mir-1266 Psoriasis 27371164 Increased MicroRNA-1266 levels as a biomarker for disease activity in psoriasis vulgaris. circulation_biomarker_diagnosis_up hsa-mir-221 Acute Myocardial Infarction 27374153 Circulating miR-221-3p as a novel marker for early prediction of acute myocardial infarction. circulation_biomarker_diagnosis_up hsa-mir-146b Acute Kidney Failure 27400799 "The results showed that in acute kidney injury induced by cisplatin, miR-146b in serum increased more quickly than did the usual indexes of kidney injury and decreased with restoration of MSCs." circulation_biomarker_diagnosis_up hsa-mir-21 Prostate Neoplasms 27434290 The expression levels of miR-21 in PCa group were increased compared to BPH and control group circulation_biomarker_diagnosis_up hsa-mir-133a Sepsis 27434558 The mRNA expressions of serum miR-155-5p and miR-133a-3p were gradually increased with the aggravation of sepsis. circulation_biomarker_diagnosis_up hsa-mir-155 Sepsis 27434558 The mRNA expressions of serum miR-155-5p and miR-133a-3p were gradually increased with the aggravation of sepsis. circulation_biomarker_diagnosis_up hsa-mir-223 Oral Neoplasms 27441818 "circulating miR-223 levels were significantly higher (~2-fold, P< 0.05) in patients with oral cancer (n = 31) than in those without cancer (n = 31)." circulation_biomarker_diagnosis_up hsa-mir-30 Diabetic Nephropathy 27470555 "We found urinary exosomalmiR-133b, miR-342, and miR-30a were expressed at significantly elevated levels in T2DN patients (P<0.001) compared to normal." circulation_biomarker_diagnosis_up hsa-mir-342 Diabetic Nephropathy 27470555 "We found urinary exosomalmiR-133b, miR-342, and miR-30a were expressed at significantly elevated levels in T2DN patients (P<0.001) compared to normal." circulation_biomarker_diagnosis_up hsa-mir-122 Acute Pancreatitis 27477940 "In mice, we found that LPS-induced inflammation increases blood levels of MIR122, which reduces expression of Epo in the kidney;" circulation_biomarker_diagnosis_up hsa-mir-22 Myocardial Infarction 27484208 Subsequent validation in an independent patient group confirmed that miRâ€?33b and miRâ€?2â€?p were significantly up‑regulated in the serum of patients with AMI. circulation_biomarker_diagnosis_up hsa-mir-106b Schizophrenia 27489379 "Schizophrenia patients showed statistically significant upregulation of five microRNAs: miR9-5p (p=0.002), miR29a-3p (pï¼?.001), miR106b-5p (p=0.002), miR125a-3p (pï¼?.001), and miR125b-3p (p=0.018)." circulation_biomarker_diagnosis_up hsa-mir-29a Schizophrenia 27489379 "Schizophrenia patients showed statistically significant upregulation of five microRNAs: miR9-5p (p=0.002), miR29a-3p (pï¼?.001), miR106b-5p (p=0.002), miR125a-3p (pï¼?.001), and miR125b-3p (p=0.018)." circulation_biomarker_diagnosis_up hsa-mir-19a Allergic Rhinitis 27491928 "The results showed that the levels of miR-19a, but not the rest of the 5 members (miR-17, miR-18a, miR-19b, miR-20a, and miR-92a), were significantly higher in peripheral B cells from AR patients as than in B cells from healthy participants." circulation_biomarker_diagnosis_up hsa-mir-146a Atherosclerosis 27502756 "In monocytes, miR124a and -125a were low, while miR-146a and miR-155 appeared elevated." circulation_biomarker_diagnosis_up hsa-mir-21 Systemic Lupus Erythematosus 27510529 miR-21 was high expressed in SLE patients compared to their first-degree relatives and controls. circulation_biomarker_diagnosis_up hsa-mir-147 Diabetes Mellitus 27518498 Analysis for serum microRNAs expression showed the distinctive and synergistic upregulation of miR-147 with periodontitis-induced effects in rats circulation_biomarker_diagnosis_up hsa-mir-122 Acute Coronary Syndrome 27519051 "MiR-223, miR-92a, miR-486, miR-122, miR-125a and miR-146a levels were higher in the hyperglycemic ACS compared to normoglycemic sera." circulation_biomarker_diagnosis_up hsa-mir-125a Acute Coronary Syndrome 27519051 "MiR-223, miR-92a, miR-486, miR-122, miR-125a and miR-146a levels were higher in the hyperglycemic ACS compared to normoglycemic sera." circulation_biomarker_diagnosis_up hsa-mir-146a Acute Coronary Syndrome 27519051 "MiR-223, miR-92a, miR-486, miR-122, miR-125a and miR-146a levels were higher in the hyperglycemic ACS compared to normoglycemic sera." circulation_biomarker_diagnosis_up hsa-mir-223 Acute Coronary Syndrome 27519051 "MiR-223, miR-92a, miR-486, miR-122, miR-125a and miR-146a levels were higher in the hyperglycemic ACS compared to normoglycemic sera." circulation_biomarker_diagnosis_up hsa-mir-486 Acute Coronary Syndrome 27519051 "MiR-223, miR-92a, miR-486, miR-122, miR-125a and miR-146a levels were higher in the hyperglycemic ACS compared to normoglycemic sera." circulation_biomarker_diagnosis_up hsa-mir-92a Acute Coronary Syndrome 27519051 "MiR-223, miR-92a, miR-486, miR-122, miR-125a and miR-146a levels were higher in the hyperglycemic ACS compared to normoglycemic sera." circulation_biomarker_diagnosis_up hsa-mir-21 Kideny Transplant Rejection 27521993 our findings indicated that the aberrant urinary miR-21 and miR-200b expression levels were accompanied with renal allograft dysfunction and IFTA. circulation_biomarker_diagnosis_up hsa-mir-217 "Diabetes Mellitus, Type 2" 27522360 "Compared with control, serum microRNA-217 levels were significantly increased in type 2 diabetes patients" circulation_biomarker_diagnosis_up hsa-mir-146a Psoriasis 27535005 "Psoriasis patients presented, at baseline, increased expression of miRNA-155, let-7i, miRNA-146a, miRNA-21 and miRNA-223 in PBMCs, plus miRNA-21, miRNA-146a and miRNA-223 in plasma." circulation_biomarker_diagnosis_up hsa-mir-155 Psoriasis 27535005 "Psoriasis patients presented, at baseline, increased expression of miRNA-155, let-7i, miRNA-146a, miRNA-21 and miRNA-223 in PBMCs, plus miRNA-21, miRNA-146a and miRNA-223 in plasma." circulation_biomarker_diagnosis_up hsa-mir-21 Psoriasis 27535005 "Psoriasis patients presented, at baseline, increased expression of miRNA-155, let-7i, miRNA-146a, miRNA-21 and miRNA-223 in PBMCs, plus miRNA-21, miRNA-146a and miRNA-223 in plasma." circulation_biomarker_diagnosis_up hsa-mir-223 Psoriasis 27535005 "Psoriasis patients presented, at baseline, increased expression of miRNA-155, let-7i, miRNA-146a, miRNA-21 and miRNA-223 in PBMCs, plus miRNA-21, miRNA-146a and miRNA-223 in plasma." circulation_biomarker_diagnosis_up hsa-mir-181a "Lymphoma, B-Cell" 27535859 "The expression of hsa-miR-29a , hsa-miR-126 and has-miR-181 family were significantly different in B-ALL." circulation_biomarker_diagnosis_up hsa-mir-181c "Leukemia, Lymphoblastic" 27535859 "The expression of hsa-miR-29a , hsa-miR-126 and has-miR-181 family were significantly different in B-ALL." circulation_biomarker_diagnosis_up hsa-mir-155 Leukemia 27619068 MicroRNA-155 is upregulated in MLL-rearranged AML but its absence does not affect leukemia development. circulation_biomarker_diagnosis_up hsa-mir-126 Arteriosclerosis Obliterans 27766047 "In smokers who completely attained smoking cessation, both RH-PAT index and plasma miR-126 values were increased" circulation_biomarker_diagnosis_up hsa-mir-146a Melanoma 27895580 Increased Levels of miRNA-146a in Serum and Histologic Samples of Patients with Uveal Melanoma. circulation_biomarker_diagnosis_up hsa-mir-127 "Carcinoma, Breast" 27983524 Combined detection of plasma miR-127-3p and HE4 improves the diagnostic efficacy of breast cancer. circulation_biomarker_diagnosis_up hsa-mir-140 "Leukemia, Myeloid, Chronic" 28197964 Up-regulated exosomal miRNA-140-3p in CML patients with musculoskeletal pain associated with discontinuation of tyrosine kinase inhibitors. circulation_biomarker_diagnosis_up hsa-mir-16 Hearing Loss 28224282 "The plasma levels of miR-24-3p, miR-16-5p,miR-185-5p, and miR-451a were upregulated during noise exposures, and increased levels of miR-21 have been found in vestibular schwannomas and human cholesteatoma" circulation_biomarker_diagnosis_up hsa-mir-185 Hearing Loss 28224282 "The plasma levels of miR-24-3p, miR-16-5p,miR-185-5p, and miR-451a were upregulated during noise exposures, and increased levels of miR-21 have been found in vestibular schwannomas and human cholesteatoma" circulation_biomarker_diagnosis_up hsa-mir-21 Cholesteatoma 28224282 "The plasma levels of miR-24-3p, miR-16-5p,miR-185-5p, and miR-451a were upregulated during noise exposures, and increased levels of miR-21 have been found in vestibular schwannomas and human cholesteatoma" circulation_biomarker_diagnosis_up hsa-mir-21 Neurilemmoma 28224282 "The plasma levels of miR-24-3p, miR-16-5p,miR-185-5p, and miR-451a were upregulated during noise exposures, and increased levels of miR-21 have been found in vestibular schwannomas and human cholesteatoma" circulation_biomarker_diagnosis_up hsa-mir-24 Hearing Loss 28224282 "The plasma levels of miR-24-3p, miR-16-5p,miR-185-5p, and miR-451a were upregulated during noise exposures, and increased levels of miR-21 have been found in vestibular schwannomas and human cholesteatoma" circulation_biomarker_diagnosis_up hsa-mir-451a Hearing Loss 28224282 "The plasma levels of miR-24-3p, miR-16-5p,miR-185-5p, and miR-451a were upregulated during noise exposures, and increased levels of miR-21 have been found in vestibular schwannomas and human cholesteatoma" circulation_biomarker_diagnosis_up hsa-mir-29a Atherosclerosis 28250354 Elevated Plasma miR-29a Levels Are Associated with Increased Carotid Intima-Media Thickness in Atherosclerosis Patients. circulation_biomarker_diagnosis_up hsa-mir-155 Heart Failure 28319523 Plasma Levels of MicroRNA-155 Are Upregulated with Long-Term Left Ventricular Assist Device Support. circulation_biomarker_diagnosis_up hsa-mir-142 Kideny Transplant Rejection 28380212 Upregulation of microRNA 142-3p in the peripheral blood and urinary cells of kidney transplant recipients with post-transplant graft dysfunction. circulation_biomarker_diagnosis_up hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 28407516 Quantitative miR analysis in chronic lymphocytic leukaemia/small lymphocytic lymphoma - proliferation centres are characterized by high miR-92a and miR-155 and low miR-150 expression. circulation_biomarker_diagnosis_up hsa-mir-92a "Leukemia, Lymphocytic, Chronic, B-Cell" 28407516 Quantitative miR analysis in chronic lymphocytic leukaemia/small lymphocytic lymphoma - proliferation centres are characterized by high miR-92a and miR-155 and low miR-150 expression. circulation_biomarker_diagnosis_up hsa-mir-125b "Leukemia-Lymphoma, Precursor B-Cell Lymphoblastic" 28415578 High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia. circulation_biomarker_diagnosis_up hsa-mir-21 Vascular Disease [unspecific] 28464406 "miR-21 and miR-92 levels increased, but did not reach the level of significance" circulation_biomarker_diagnosis_up hsa-mir-92 Vascular Disease [unspecific] 28464406 "miR-21 and miR-92 levels increased, but did not reach the level of significance" circulation_biomarker_diagnosis_up hsa-mir-196b "Leukemia, Myeloid, Acute" 28507466 High level of miR-196b at newly diagnosed pediatric acute myeloid leukemia predicts a poor outcome. circulation_biomarker_diagnosis_up hsa-mir-155 Human Immunodeficiency Virus Infection 28627655 Elevated expression of miR-155 is associated with the differentiation of CD8+ T cells in patients with HIV-1. circulation_biomarker_diagnosis_up hsa-mir-125b Rheumatoid Arthritis 28738524 Elevated microRNA-125b promotes inflammation in rheumatoid arthritis by activation of NF-¦ÊB pathway. circulation_biomarker_diagnosis_up hsa-mir-126 Coronary Artery Disease 28751542 "patients with stenosis showed an increase of circulating miRNA-21, miRNA-126-3p, and miRNA-222 in response to cardiac stress" circulation_biomarker_diagnosis_up hsa-mir-21 Coronary Artery Disease 28751542 "patients with stenosis showed an increase of circulating miRNA-21, miRNA-126-3p, and miRNA-222 in response to cardiac stress" circulation_biomarker_diagnosis_up hsa-mir-222 Coronary Artery Disease 28751542 "patients with stenosis showed an increase of circulating miRNA-21, miRNA-126-3p, and miRNA-222 in response to cardiac stress" circulation_biomarker_diagnosis_up hsa-mir-146a Osteoarthritis 28785809 "MBT can modify the expression of miR-155, miR-181a, miR-146a, and miR-223, which are upregulated in OA" circulation_biomarker_diagnosis_up hsa-mir-155 Osteoarthritis 28785809 "MBT can modify the expression of miR-155, miR-181a, miR-146a, and miR-223, which are upregulated in OA" circulation_biomarker_diagnosis_up hsa-mir-181a Osteoarthritis 28785809 "MBT can modify the expression of miR-155, miR-181a, miR-146a, and miR-223, which are upregulated in OA" circulation_biomarker_diagnosis_up hsa-mir-223 Osteoarthritis 28785809 "MBT can modify the expression of miR-155, miR-181a, miR-146a, and miR-223, which are upregulated in OA" circulation_biomarker_diagnosis_up hsa-mir-21 Human Immunodeficiency Virus Infection 28968466 upregulation of hsa-miR-21 and hsa-miR-222 by Tat may contribute to protect against apoptosis and to anergy observed in HIV-infected CD4+ T cells circulation_biomarker_diagnosis_up hsa-mir-222 Human Immunodeficiency Virus Infection 28968466 upregulation of hsa-miR-21 and hsa-miR-222 by Tat may contribute to protect against apoptosis and to anergy observed in HIV-infected CD4+ T cells circulation_biomarker_diagnosis_up hsa-mir-19b "Leukemia, Myeloid, Acute" 29032147 High bone marrow miR-19b level predicts poor prognosis and disease recurrence in de novo acute myeloid leukemia. circulation_biomarker_diagnosis_up hsa-mir-144 Arrhythmia 29036525 "Plasma levels of miR-144-3p, 145-5p, 185-5p, and 494 were significantly elevated in definite ARVC patients with VA" circulation_biomarker_diagnosis_up hsa-mir-145 Arrhythmia 29036525 "Plasma levels of miR-144-3p, 145-5p, 185-5p, and 494 were significantly elevated in definite ARVC patients with VA" circulation_biomarker_diagnosis_up hsa-mir-185 Arrhythmia 29036525 "Plasma levels of miR-144-3p, 145-5p, 185-5p, and 494 were significantly elevated in definite ARVC patients with VA" circulation_biomarker_diagnosis_up hsa-mir-494 Arrhythmia 29036525 "Plasma levels of miR-144-3p, 145-5p, 185-5p, and 494 were significantly elevated in definite ARVC patients with VA" circulation_biomarker_diagnosis_up hsa-mir-146b Intrahepatic Cholangiocarcinoma 29095255 Both plasma and tumor tissue miR-146a high expression correlates with prolonged overall survival of surgical patients with intrahepatic cholangiocarcinoma. circulation_biomarker_diagnosis_up hsa-let-7g Migraine 29126355 " migraine patients had upregulated expression of miR-155 (6.17-fold, p?=?0.018), miR-126 (6.17-fold, p?=?0.013), and let-7g (7.37-fold, p?=?0.005)" circulation_biomarker_diagnosis_up hsa-mir-126 Migraine 29126355 " migraine patients had upregulated expression of miR-155 (6.17-fold, p?=?0.018), miR-126 (6.17-fold, p?=?0.013), and let-7g (7.37-fold, p?=?0.005)" circulation_biomarker_diagnosis_up hsa-mir-155 Migraine 29126355 " migraine patients had upregulated expression of miR-155 (6.17-fold, p?=?0.018), miR-126 (6.17-fold, p?=?0.013), and let-7g (7.37-fold, p?=?0.005)" circulation_biomarker_diagnosis_up hsa-mir-1 Myocardial Infarction 29150941 significantly elevated levels of miRNA-1 in post-MI old heart could be predictive of cardiac injury in older mice as the high risk biomarker for MI in older individuals circulation_biomarker_diagnosis_up hsa-mir-210 Neoplasms [unspecific] 29187235 miR-210 was >?sixfold higher in the TCC group compared to the control group circulation_biomarker_diagnosis_up hsa-mir-139 Rheumatoid Arthritis 29191214 "The expression levels of miR-139-3p, miR-204, miR-214, and miR-760 increased in RA patients receiving biologic agents" circulation_biomarker_diagnosis_up hsa-mir-204 Rheumatoid Arthritis 29191214 "The expression levels of miR-139-3p, miR-204, miR-214, and miR-760 increased in RA patients receiving biologic agents" circulation_biomarker_diagnosis_up hsa-mir-214 Rheumatoid Arthritis 29191214 "The expression levels of miR-139-3p, miR-204, miR-214, and miR-760 increased in RA patients receiving biologic agents" circulation_biomarker_diagnosis_up hsa-mir-760 Rheumatoid Arthritis 29191214 "The expression levels of miR-139-3p, miR-204, miR-214, and miR-760 increased in RA patients receiving biologic agents" circulation_biomarker_diagnosis_up hsa-mir-21 Myocardial Infarction 29197221 "Expression of miRNA-21 was upregulated in the serum of elderly patients with AMI, which inhibited TNF-a induced apoptosis in HCM by activating the JNK/p38/caspase-3 signaling pathway" circulation_biomarker_diagnosis_up hsa-mir-126 Multiple Sclerosis 29325906 "The upregulation of miR-126-3p, miR-146b-5p, miR-155, miR-196a-5p, miR-21-5p, miR-223-3p, miR-326 and miR-379-5p in remission compared to relapse was observed" circulation_biomarker_diagnosis_up hsa-mir-146b Multiple Sclerosis 29325906 "The upregulation of miR-126-3p, miR-146b-5p, miR-155, miR-196a-5p, miR-21-5p, miR-223-3p, miR-326 and miR-379-5p in remission compared to relapse was observed" circulation_biomarker_diagnosis_up hsa-mir-155 Multiple Sclerosis 29325906 "The upregulation of miR-126-3p, miR-146b-5p, miR-155, miR-196a-5p, miR-21-5p, miR-223-3p, miR-326 and miR-379-5p in remission compared to relapse was observed" circulation_biomarker_diagnosis_up hsa-mir-196a Multiple Sclerosis 29325906 "The upregulation of miR-126-3p, miR-146b-5p, miR-155, miR-196a-5p, miR-21-5p, miR-223-3p, miR-326 and miR-379-5p in remission compared to relapse was observed" circulation_biomarker_diagnosis_up hsa-mir-21 Multiple Sclerosis 29325906 "The upregulation of miR-126-3p, miR-146b-5p, miR-155, miR-196a-5p, miR-21-5p, miR-223-3p, miR-326 and miR-379-5p in remission compared to relapse was observed" circulation_biomarker_diagnosis_up hsa-mir-223 Multiple Sclerosis 29325906 "The upregulation of miR-126-3p, miR-146b-5p, miR-155, miR-196a-5p, miR-21-5p, miR-223-3p, miR-326 and miR-379-5p in remission compared to relapse was observed" circulation_biomarker_diagnosis_up hsa-mir-326 Multiple Sclerosis 29325906 "The upregulation of miR-126-3p, miR-146b-5p, miR-155, miR-196a-5p, miR-21-5p, miR-223-3p, miR-326 and miR-379-5p in remission compared to relapse was observed" circulation_biomarker_diagnosis_up hsa-mir-379 Multiple Sclerosis 29325906 "The upregulation of miR-126-3p, miR-146b-5p, miR-155, miR-196a-5p, miR-21-5p, miR-223-3p, miR-326 and miR-379-5p in remission compared to relapse was observed" circulation_biomarker_diagnosis_up hsa-mir-21 Ovarian Neoplasms 29373877 miR-21 may be used as a diagnostic biomarker for human ovarian cancer circulation_biomarker_diagnosis_up hsa-mir-191 Pancreatic Neoplasms 29385987 "An elevated expression of serum exosomal microRNA-191, -21, -451a of pancreatic neoplasm is considered to be efficient diagnostic marker" circulation_biomarker_diagnosis_up hsa-mir-21 Pancreatic Neoplasms 29385987 "An elevated expression of serum exosomal microRNA-191, -21, -451a of pancreatic neoplasm is considered to be efficient diagnostic marker" circulation_biomarker_diagnosis_up hsa-mir-451a Pancreatic Neoplasms 29385987 "An elevated expression of serum exosomal microRNA-191, -21, -451a of pancreatic neoplasm is considered to be efficient diagnostic marker" circulation_biomarker_diagnosis_up hsa-mir-146b Stroke 29402769 upregulated serum miR-146b in acute ischemic stroke might be a potential biomarker for AIS evaluation circulation_biomarker_diagnosis_up hsa-mir-210 Acute Cerebral Infarction 29434712 "miR-210 is upregulated in the serum of patients with ACI, and miR-210 may be involved in the pathogenesis of ACI through regulating the proliferation and apoptosis of endothelial cells" circulation_biomarker_diagnosis_up hsa-mir-1 Cardiovascular Diseases [unspecific] 29506853 Plasma microRNAs reflecting cardiac and inflammatory injury in coronary artery bypass grafting surgery circulation_biomarker_diagnosis_up hsa-mir-133a Cardiovascular Diseases [unspecific] 29506853 Plasma microRNAs reflecting cardiac and inflammatory injury in coronary artery bypass grafting surgery circulation_biomarker_diagnosis_up hsa-mir-208a Cardiovascular Diseases [unspecific] 29506853 Plasma microRNAs reflecting cardiac and inflammatory injury in coronary artery bypass grafting surgery circulation_biomarker_diagnosis_up hsa-mir-21 Cholangiocarcinoma 29516989 serum miR-21 was a promising biomarker for diagnosing the late stage CCA and would have potential to be a useful prognostic biomarker of CCA circulation_biomarker_diagnosis_up hsa-mir-155 Hepatitis C Virus Infection 29528577 MicroRNA-155 is a relatively reliable marker for HCC detection circulation_biomarker_diagnosis_up hsa-mir-208a Heart Failure 29559958 "miR-208a, a microRNA that is a key factor in promoting cardiovascular dysfunction during cardiac hypertrophy processes of heart failure, has its circulating levels increased during chronic indeterminate phase when compared to cardiac (CARD) clinical forms in patients with Chagas disease" circulation_biomarker_diagnosis_up hsa-mir-21 Breast Neoplasms 29679553 "Assessment of miRNAs in serum samples can be applied as minimally non-invasive markers for early detection of breast cancer, and as discriminator between different clinicopathological characters" circulation_biomarker_diagnosis_up hsa-mir-222 Breast Neoplasms 29679553 "Assessment of miRNAs in serum samples can be applied as minimally non-invasive markers for early detection of breast cancer, and as discriminator between different clinicopathological characters" circulation_biomarker_diagnosis_up hsa-mir-373 Breast Neoplasms 29679553 "Assessment of miRNAs in serum samples can be applied as minimally non-invasive markers for early detection of breast cancer, and as discriminator between different clinicopathological characters" circulation_biomarker_diagnosis_up hsa-mir-144 Familial Mediterranean Fever 29787577 "four miRNAs were upregulated (miR-144-3p, miR-21-5p, miR-4454, and miR-451a), and three were downregulated (miR-107, let-7d-5p, and miR-148b-3p)" circulation_biomarker_diagnosis_up hsa-mir-21 Familial Mediterranean Fever 29787577 "four miRNAs were upregulated (miR-144-3p, miR-21-5p, miR-4454, and miR-451a), and three were downregulated (miR-107, let-7d-5p, and miR-148b-3p)" circulation_biomarker_diagnosis_up hsa-mir-4454 Familial Mediterranean Fever 29787577 "four miRNAs were upregulated (miR-144-3p, miR-21-5p, miR-4454, and miR-451a), and three were downregulated (miR-107, let-7d-5p, and miR-148b-3p)" circulation_biomarker_diagnosis_up hsa-mir-451a Familial Mediterranean Fever 29787577 "four miRNAs were upregulated (miR-144-3p, miR-21-5p, miR-4454, and miR-451a), and three were downregulated (miR-107, let-7d-5p, and miR-148b-3p)" circulation_biomarker_diagnosis_up hsa-mir-21 "Leukemia, Myeloid" 29795410 MiR-21 was found to be normally upregulated in all types of ML circulation_biomarker_diagnosis_up hsa-mir-300 Traumatic Brain Injury 29873258 miR-300-3p and miR-598-3p increased while miR-450-3p and miR-194-5p significantly decreased following TBI circulation_biomarker_diagnosis_up hsa-mir-598 Traumatic Brain Injury 29873258 miR-300-3p and miR-598-3p increased while miR-450-3p and miR-194-5p significantly decreased following TBI circulation_biomarker_diagnosis_up hsa-mir-195 "Diabetes Mellitus, Gestational" 29879500 "increased miRNA expression, especially miR-195-5p, in plasma is characteristic of and causally related to the development of GDM" circulation_biomarker_diagnosis_up hsa-mir-144 "Carcinoma, Thyroid" 29885402 Evaluation of miRNAs expression in medullary thyroid carcinoma tissue samples: miR-34a and miR-144 as promising overexpressed markers in MTC. circulation_biomarker_diagnosis_up hsa-mir-34a "Carcinoma, Thyroid" 29885402 Evaluation of miRNAs expression in medullary thyroid carcinoma tissue samples: miR-34a and miR-144 as promising overexpressed markers in MTC. circulation_biomarker_diagnosis_up hsa-mir-223 Coronary Artery Disease 29888618 Association between elevated plasma microRNA-223 content and severity of coronary heart disease. circulation_biomarker_diagnosis_up hsa-mir-4649 Chronic Brucellosis 29897958 The microRNA expression signature of CD4+ T cells in the transition of brucellosis into chronicity. circulation_biomarker_diagnosis_up hsa-mir-182 Acute Lung Injury 29904430 "9 miRNAs were significantly upregulated (miR-1843-3p, miR-323-3p, miR-183-5p, miR-182 and miR-196b-3p) or downregulated (miR-547-3p, miR-301b-5p, miR-503-3p and miR-142-3p)" circulation_biomarker_diagnosis_up hsa-mir-183 Acute Lung Injury 29904430 "9 miRNAs were significantly upregulated (miR-1843-3p, miR-323-3p, miR-183-5p, miR-182 and miR-196b-3p) or downregulated (miR-547-3p, miR-301b-5p, miR-503-3p and miR-142-3p)" circulation_biomarker_diagnosis_up hsa-mir-1843 Acute Lung Injury 29904430 "9 miRNAs were significantly upregulated (miR-1843-3p, miR-323-3p, miR-183-5p, miR-182 and miR-196b-3p) or downregulated (miR-547-3p, miR-301b-5p, miR-503-3p and miR-142-3p)" circulation_biomarker_diagnosis_up hsa-mir-196b Acute Lung Injury 29904430 "9 miRNAs were significantly upregulated (miR-1843-3p, miR-323-3p, miR-183-5p, miR-182 and miR-196b-3p) or downregulated (miR-547-3p, miR-301b-5p, miR-503-3p and miR-142-3p)" circulation_biomarker_diagnosis_up hsa-mir-323 Acute Lung Injury 29904430 "9 miRNAs were significantly upregulated (miR-1843-3p, miR-323-3p, miR-183-5p, miR-182 and miR-196b-3p) or downregulated (miR-547-3p, miR-301b-5p, miR-503-3p and miR-142-3p)" circulation_biomarker_diagnosis_up hsa-mir-135a Parkinson Disease 29935433 "We identified differential expression of 10 miRNA of which 5 were upregulated in PD (miR-9-5p, miR-135a-5p, miR-135b-5p, miR-449a, and miR-449b-5p) and 5 downregulated (miR-141-3p, miR-199a-5p, miR-299-5p, miR-518e-3p, and miR-519a-3p)" circulation_biomarker_diagnosis_up hsa-mir-135b Parkinson Disease 29935433 "We identified differential expression of 10 miRNA of which 5 were upregulated in PD (miR-9-5p, miR-135a-5p, miR-135b-5p, miR-449a, and miR-449b-5p) and 5 downregulated (miR-141-3p, miR-199a-5p, miR-299-5p, miR-518e-3p, and miR-519a-3p)" circulation_biomarker_diagnosis_up hsa-mir-449a Parkinson Disease 29935433 "We identified differential expression of 10 miRNA of which 5 were upregulated in PD (miR-9-5p, miR-135a-5p, miR-135b-5p, miR-449a, and miR-449b-5p) and 5 downregulated (miR-141-3p, miR-199a-5p, miR-299-5p, miR-518e-3p, and miR-519a-3p)" circulation_biomarker_diagnosis_up hsa-mir-449b Parkinson Disease 29935433 "We identified differential expression of 10 miRNA of which 5 were upregulated in PD (miR-9-5p, miR-135a-5p, miR-135b-5p, miR-449a, and miR-449b-5p) and 5 downregulated (miR-141-3p, miR-199a-5p, miR-299-5p, miR-518e-3p, and miR-519a-3p)" circulation_biomarker_diagnosis_up hsa-mir-9 Parkinson Disease 29935433 "We identified differential expression of 10 miRNA of which 5 were upregulated in PD (miR-9-5p, miR-135a-5p, miR-135b-5p, miR-449a, and miR-449b-5p) and 5 downregulated (miR-141-3p, miR-199a-5p, miR-299-5p, miR-518e-3p, and miR-519a-3p)" circulation_biomarker_diagnosis_up hsa-mir-101a Peripheral Nerve Injury 29960630 "4 miRs (miR-101a, miR-138, miR-338, and miR-142) levels were finally validated for over-expression by quantitative (PCR) reaction" circulation_biomarker_diagnosis_up hsa-mir-138 Peripheral Nerve Injury 29960630 "4 miRs (miR-101a, miR-138, miR-338, and miR-142) levels were finally validated for over-expression by quantitative (PCR) reaction" circulation_biomarker_diagnosis_up hsa-mir-142 Peripheral Nerve Injury 29960630 "4 miRs (miR-101a, miR-138, miR-338, and miR-142) levels were finally validated for over-expression by quantitative (PCR) reaction" circulation_biomarker_diagnosis_up hsa-mir-338 Peripheral Nerve Injury 29960630 "4 miRs (miR-101a, miR-138, miR-338, and miR-142) levels were finally validated for over-expression by quantitative (PCR) reaction" circulation_biomarker_diagnosis_up hsa-mir-551b Acute Pancreatitis 29989302 Elevated Level of miR-551b-5p is Associated With Inflammation and Disease Progression in Patients With Severe Acute Pancreatitis. circulation_biomarker_diagnosis_up hsa-mir-133a Glycogen Storage Disease II 29997386 miR-133a levels were significantly higher in Pompe disease patients than in controls and correlated with phenotype severity circulation_biomarker_diagnosis_up hsa-mir-221 Hypertrophy 30009269 an elevated miR-221 level is potentially associated with an increased risk of SCD in subjects with cardiac hypertrophy circulation_biomarker_diagnosis_up hsa-mir-10a Diabetic Nephropathy 30019103 "three up-regulated (miR-21-5p, miR-146a-5p, miR-10a-5p) and two down-regulated (miR-25-3p and miR-26a-5p) miRNAs" circulation_biomarker_diagnosis_up hsa-mir-146a Diabetic Nephropathy 30019103 "three up-regulated (miR-21-5p, miR-146a-5p, miR-10a-5p) and two down-regulated (miR-25-3p and miR-26a-5p) miRNAs" circulation_biomarker_diagnosis_up hsa-mir-21 Diabetic Nephropathy 30019103 "three up-regulated (miR-21-5p, miR-146a-5p, miR-10a-5p) and two down-regulated (miR-25-3p and miR-26a-5p) miRNAs" circulation_biomarker_diagnosis_up hsa-mir-462a Anemia 30041004 "two miRNAs, miR-462a-5p and miR-125b-5p, showed increased and decreased expression, respectively, during ISAV infection" circulation_biomarker_diagnosis_up hsa-mir-103 Colorectal Carcinoma 30058684 Upregulation of serum miR-103 predicts unfavorable prognosis in patients with colorectal cancer. circulation_biomarker_diagnosis_up hsa-mir-100 "Squamous Cell Carcinoma, Esophageal" 30127929 "Among the 5 miRNAs considered (miR-21, miR-223, miR-375, miR-25 and miR-100), miR-21 and miR-223 were significantly overexpressed whereas miR-375 expression was reduced in patients with ESCC compared with healthy individuals" circulation_biomarker_diagnosis_up hsa-mir-21 "Squamous Cell Carcinoma, Esophageal" 30127929 "Among the 5 miRNAs considered (miR-21, miR-223, miR-375, miR-25 and miR-100), miR-21 and miR-223 were significantly overexpressed whereas miR-375 expression was reduced in patients with ESCC compared with healthy individuals" circulation_biomarker_diagnosis_up hsa-mir-223 "Squamous Cell Carcinoma, Esophageal" 30127929 "Among the 5 miRNAs considered (miR-21, miR-223, miR-375, miR-25 and miR-100), miR-21 and miR-223 were significantly overexpressed whereas miR-375 expression was reduced in patients with ESCC compared with healthy individuals" circulation_biomarker_diagnosis_up hsa-mir-25 "Squamous Cell Carcinoma, Esophageal" 30127929 "Among the 5 miRNAs considered (miR-21, miR-223, miR-375, miR-25 and miR-100), miR-21 and miR-223 were significantly overexpressed whereas miR-375 expression was reduced in patients with ESCC compared with healthy individuals" circulation_biomarker_diagnosis_up hsa-mir-125b Multiple Myeloma 30128020 The diagnostic and prognostic value of plasma microRNA-125b-5p in patients with multiple myeloma. circulation_biomarker_diagnosis_up hsa-mir-221 Rheumatoid Arthritis 30132091 Upregulation of miR-221/222 expression in rheumatoid arthritis (RA) patients: correlation with disease activity. circulation_biomarker_diagnosis_up hsa-mir-222 Rheumatoid Arthritis 30132091 Upregulation of miR-221/222 expression in rheumatoid arthritis (RA) patients: correlation with disease activity. circulation_biomarker_diagnosis_up hsa-mir-1255a Stroke 30135469 "six microRNAs showed significantly increased expression - miR-371-3p, miR-524, miR-520g, miR-1255A, miR-453, and miR-583, while 3 showed significantly decreased expression - miR-941, miR-449b, and miR-581" circulation_biomarker_diagnosis_up hsa-mir-371 Stroke 30135469 "six microRNAs showed significantly increased expression - miR-371-3p, miR-524, miR-520g, miR-1255A, miR-453, and miR-583, while 3 showed significantly decreased expression - miR-941, miR-449b, and miR-581" circulation_biomarker_diagnosis_up hsa-mir-453 Stroke 30135469 "six microRNAs showed significantly increased expression - miR-371-3p, miR-524, miR-520g, miR-1255A, miR-453, and miR-583, while 3 showed significantly decreased expression - miR-941, miR-449b, and miR-581" circulation_biomarker_diagnosis_up hsa-mir-520g Stroke 30135469 "six microRNAs showed significantly increased expression - miR-371-3p, miR-524, miR-520g, miR-1255A, miR-453, and miR-583, while 3 showed significantly decreased expression - miR-941, miR-449b, and miR-581" circulation_biomarker_diagnosis_up hsa-mir-524 Stroke 30135469 "six microRNAs showed significantly increased expression - miR-371-3p, miR-524, miR-520g, miR-1255A, miR-453, and miR-583, while 3 showed significantly decreased expression - miR-941, miR-449b, and miR-581" circulation_biomarker_diagnosis_up hsa-mir-583 Stroke 30135469 "six microRNAs showed significantly increased expression - miR-371-3p, miR-524, miR-520g, miR-1255A, miR-453, and miR-583, while 3 showed significantly decreased expression - miR-941, miR-449b, and miR-581" circulation_biomarker_diagnosis_up hsa-mir-125a "Diabetes Mellitus, Type 2" 30150203 Up regulation of miR-125a in WAT of type 2 Diabetes mellitus have been observed circulation_biomarker_diagnosis_up hsa-mir-148a Prostate Neoplasms 30160020 Increased levels of serum miR-148a-3p are associated with prostate cancer. circulation_biomarker_diagnosis_up hsa-mir-122 Obesity 30160046 Pilot study on circulating miRNA signature in children with obesity born small for gestational age and appropriate for gestational age. circulation_biomarker_diagnosis_up hsa-mir-423 Obesity 30160046 Pilot study on circulating miRNA signature in children with obesity born small for gestational age and appropriate for gestational age. circulation_biomarker_diagnosis_up hsa-mir-484 Obesity 30160046 Pilot study on circulating miRNA signature in children with obesity born small for gestational age and appropriate for gestational age. circulation_biomarker_diagnosis_up hsa-mir-486 Obesity 30160046 Pilot study on circulating miRNA signature in children with obesity born small for gestational age and appropriate for gestational age. circulation_biomarker_diagnosis_up hsa-mir-532 Obesity 30160046 Pilot study on circulating miRNA signature in children with obesity born small for gestational age and appropriate for gestational age. circulation_biomarker_diagnosis_up hsa-mir-92a Obesity 30160046 Pilot study on circulating miRNA signature in children with obesity born small for gestational age and appropriate for gestational age. circulation_biomarker_diagnosis_up hsa-let-7i Diabetic Nephropathy 30165157 "a urinary EV miRNA signature was found to comprise increased levels of let-7i-3p, miR-24-3p and miR-27b-3p, and decreased levels of miR-15b-5p, to identify patients with MIC" circulation_biomarker_diagnosis_up hsa-mir-24 Diabetic Nephropathy 30165157 "a urinary EV miRNA signature was found to comprise increased levels of let-7i-3p, miR-24-3p and miR-27b-3p, and decreased levels of miR-15b-5p, to identify patients with MIC" circulation_biomarker_diagnosis_up hsa-mir-27b Diabetic Nephropathy 30165157 "a urinary EV miRNA signature was found to comprise increased levels of let-7i-3p, miR-24-3p and miR-27b-3p, and decreased levels of miR-15b-5p, to identify patients with MIC" circulation_biomarker_diagnosis_up hsa-mir-21 Diabetic Nephropathy 30167868 "In the validation sample, miR-21-3p and miR-378-3p were confirmed to be upregulated in patients with severe DKD, while miR-16-5p and miR-29a-3p were downregulated in this group compared to T1DM controls and patients with moderate DKD" circulation_biomarker_diagnosis_up hsa-mir-378 Diabetic Nephropathy 30167868 "In the validation sample, miR-21-3p and miR-378-3p were confirmed to be upregulated in patients with severe DKD, while miR-16-5p and miR-29a-3p were downregulated in this group compared to T1DM controls and patients with moderate DKD" circulation_biomarker_diagnosis_up hsa-mir-203 "Carcinoma, Cervical" 30191988 "The upregulation of some circulating miRNAs, for example, miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue-specific miRNAs, for example, miR-7, miR-10a, miR-17-5p, miR-135b, miR-149, and miR-203 have been found in patients with CC" circulation_biomarker_diagnosis_up hsa-mir-205 "Carcinoma, Cervical" 30191988 "The upregulation of some circulating miRNAs, for example, miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue-specific miRNAs, for example, miR-7, miR-10a, miR-17-5p, miR-135b, miR-149, and miR-203 have been found in patients with CC" circulation_biomarker_diagnosis_up hsa-mir-20a "Carcinoma, Cervical" 30191988 "The upregulation of some circulating miRNAs, for example, miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue-specific miRNAs, for example, miR-7, miR-10a, miR-17-5p, miR-135b, miR-149, and miR-203 have been found in patients with CC" circulation_biomarker_diagnosis_up hsa-mir-21 "Carcinoma, Cervical" 30191988 "The upregulation of some circulating miRNAs, for example, miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue-specific miRNAs, for example, miR-7, miR-10a, miR-17-5p, miR-135b, miR-149, and miR-203 have been found in patients with CC" circulation_biomarker_diagnosis_up hsa-mir-218 "Carcinoma, Cervical" 30191988 "The upregulation of some circulating miRNAs, for example, miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue-specific miRNAs, for example, miR-7, miR-10a, miR-17-5p, miR-135b, miR-149, and miR-203 have been found in patients with CC" circulation_biomarker_diagnosis_up hsa-mir-485 "Carcinoma, Cervical" 30191988 "The upregulation of some circulating miRNAs, for example, miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue-specific miRNAs, for example, miR-7, miR-10a, miR-17-5p, miR-135b, miR-149, and miR-203 have been found in patients with CC" circulation_biomarker_diagnosis_up hsa-mir-20a "Diabetes Mellitus, Type 1" 30194557 "Increased expression of microRNAs, miR-20a and miR-326 in PBMCs of patients with type 1 diabetes." circulation_biomarker_diagnosis_up hsa-mir-326 "Diabetes Mellitus, Type 1" 30194557 "Increased expression of microRNAs, miR-20a and miR-326 in PBMCs of patients with type 1 diabetes." circulation_biomarker_diagnosis_up hsa-mir-150 "Diabetes Mellitus, Type 2" 30195754 "Cox regression analyses showed that patients with low miR-103, miR-28-3p, miR-29a, and miR-9 and high miR-30a-5p and miR-150 circulating levels have a higher risk of disease" circulation_biomarker_diagnosis_up hsa-mir-30a "Diabetes Mellitus, Type 2" 30195754 "Cox regression analyses showed that patients with low miR-103, miR-28-3p, miR-29a, and miR-9 and high miR-30a-5p and miR-150 circulating levels have a higher risk of disease" circulation_biomarker_diagnosis_up hsa-mir-126 Obesity 30248300 Circulating microRNAs are upregulated following acute aerobic exercise in obese individuals. circulation_biomarker_diagnosis_up hsa-mir-130b Obesity 30248300 Circulating microRNAs are upregulated following acute aerobic exercise in obese individuals. circulation_biomarker_diagnosis_up hsa-mir-21 Obesity 30248300 Circulating microRNAs are upregulated following acute aerobic exercise in obese individuals. circulation_biomarker_diagnosis_up hsa-mir-221 Obesity 30248300 Circulating microRNAs are upregulated following acute aerobic exercise in obese individuals. circulation_biomarker_diagnosis_up hsa-mir-222 Obesity 30248300 Circulating microRNAs are upregulated following acute aerobic exercise in obese individuals. circulation_biomarker_diagnosis_up hsa-mir-26a Parkinson Disease 30267378 "Parkinsonian rats presented a significant increase in miR-26a and miR-34a, while miR-7 and Let7a were downregulated" circulation_biomarker_diagnosis_up hsa-mir-34a Parkinson Disease 30267378 "Parkinsonian rats presented a significant increase in miR-26a and miR-34a, while miR-7 and Let7a were downregulated" circulation_biomarker_diagnosis_up hsa-mir-1 Hyperactivity Disorder 30270454 "three miRNAs (miR-1-b, miR-741-3p, and miR-206-3p) were upregulated and four (miR-182, miR-471-5p, miR-183-5p, and miR-211-5p) were downregulated in the SHR group compared with the WKY group" circulation_biomarker_diagnosis_up hsa-mir-206 Hyperactivity Disorder 30270454 "three miRNAs (miR-1-b, miR-741-3p, and miR-206-3p) were upregulated and four (miR-182, miR-471-5p, miR-183-5p, and miR-211-5p) were downregulated in the SHR group compared with the WKY group" circulation_biomarker_diagnosis_up hsa-mir-741 Hyperactivity Disorder 30270454 "three miRNAs (miR-1-b, miR-741-3p, and miR-206-3p) were upregulated and four (miR-182, miR-471-5p, miR-183-5p, and miR-211-5p) were downregulated in the SHR group compared with the WKY group" circulation_biomarker_diagnosis_up hsa-mir-106b Preeclampsia 30277561 "There was significant upregulation of miR-106b and miR-326 ( p?=?0.0048 and 0.028, respectively) in PE patients in comparison with the control group" circulation_biomarker_diagnosis_up hsa-mir-326 Preeclampsia 30277561 "There was significant upregulation of miR-106b and miR-326 ( p?=?0.0048 and 0.028, respectively) in PE patients in comparison with the control group" circulation_biomarker_diagnosis_up hsa-mir-1260b Aplastic Anemia 30298490 expression of miR-155-5p and miR-1260b were increased in both CAA and SAA patients compared with the normal controls circulation_biomarker_diagnosis_up hsa-mir-155 Aplastic Anemia 30298490 expression of miR-155-5p and miR-1260b were increased in both CAA and SAA patients compared with the normal controls circulation_biomarker_diagnosis_up hsa-mir-30a Heart Diseases [unspecific] 30308506 "Five miRNAs were upregulated (hsa-miR-4508, hsa-miR-novel-chr8_87373, hsa-miR-30a-3p, hsa-miR-novel-chr16_26099, hsa-miR-4306) and seven miRNAs (hsa-miR-744-5p, hsa-miR-320a, hsa-miR-novel-chr9_90035, hsa-miR-101-3p, hsa-miR-150-5p, hsa-miR-342-3p, and hsa-miR-140-3p) were downregulated" circulation_biomarker_diagnosis_up hsa-mir-4306 Heart Diseases [unspecific] 30308506 "Five miRNAs were upregulated (hsa-miR-4508, hsa-miR-novel-chr8_87373, hsa-miR-30a-3p, hsa-miR-novel-chr16_26099, hsa-miR-4306) and seven miRNAs (hsa-miR-744-5p, hsa-miR-320a, hsa-miR-novel-chr9_90035, hsa-miR-101-3p, hsa-miR-150-5p, hsa-miR-342-3p, and hsa-miR-140-3p) were downregulated" circulation_biomarker_diagnosis_up hsa-mir-4508 Heart Diseases [unspecific] 30308506 "Five miRNAs were upregulated (hsa-miR-4508, hsa-miR-novel-chr8_87373, hsa-miR-30a-3p, hsa-miR-novel-chr16_26099, hsa-miR-4306) and seven miRNAs (hsa-miR-744-5p, hsa-miR-320a, hsa-miR-novel-chr9_90035, hsa-miR-101-3p, hsa-miR-150-5p, hsa-miR-342-3p, and hsa-miR-140-3p) were downregulated" circulation_biomarker_diagnosis_up hsa-mir-130 Metabolic Syndrome 30309709 "increased concentrations of miRNAS; miR-142-3p, miR-140-5p, miR-222 miR-143, miR-130, and decreased concentrations of miR-532-5p, miR-423-5p,miR-520c-3p, miR-146a, and miR-15a" circulation_biomarker_diagnosis_up hsa-mir-140 Metabolic Syndrome 30309709 "increased concentrations of miRNAS; miR-142-3p, miR-140-5p, miR-222 miR-143, miR-130, and decreased concentrations of miR-532-5p, miR-423-5p,miR-520c-3p, miR-146a, and miR-15a" circulation_biomarker_diagnosis_up hsa-mir-142 Metabolic Syndrome 30309709 "increased concentrations of miRNAS; miR-142-3p, miR-140-5p, miR-222 miR-143, miR-130, and decreased concentrations of miR-532-5p, miR-423-5p,miR-520c-3p, miR-146a, and miR-15a" circulation_biomarker_diagnosis_up hsa-mir-143 Metabolic Syndrome 30309709 "increased concentrations of miRNAS; miR-142-3p, miR-140-5p, miR-222 miR-143, miR-130, and decreased concentrations of miR-532-5p, miR-423-5p,miR-520c-3p, miR-146a, and miR-15a" circulation_biomarker_diagnosis_up hsa-mir-222 Metabolic Syndrome 30309709 "increased concentrations of miRNAS; miR-142-3p, miR-140-5p, miR-222 miR-143, miR-130, and decreased concentrations of miR-532-5p, miR-423-5p,miR-520c-3p, miR-146a, and miR-15a" circulation_biomarker_diagnosis_up hsa-mir-135b Colon Neoplasms 30311185 "the expression of the miR-135b, miR-155, and KRAS was increased in the AOM group compared to the control group in both the plasma and the colon tissue samples" circulation_biomarker_diagnosis_up hsa-mir-155 Colon Neoplasms 30311185 "the expression of the miR-135b, miR-155, and KRAS was increased in the AOM group compared to the control group in both the plasma and the colon tissue samples" circulation_biomarker_diagnosis_up hsa-mir-144 Atopic Dermatitis 30312706 Hsa-mir-144-3p is increased in umbilical cord serum of infants developing atopic dermatitis. circulation_biomarker_diagnosis_up hsa-mir-106b Behcet Disease 30317557 "T-cell-associated miRNA expression levels, miR-25, miR-106b, miR-326, and miR-93 were significantly upregulated, while miR-146a and miR-155 levels were lower in PBMCs of patients with BD" circulation_biomarker_diagnosis_up hsa-mir-25 Behcet Disease 30317557 "T-cell-associated miRNA expression levels, miR-25, miR-106b, miR-326, and miR-93 were significantly upregulated, while miR-146a and miR-155 levels were lower in PBMCs of patients with BD" circulation_biomarker_diagnosis_up hsa-mir-326 Behcet Disease 30317557 "T-cell-associated miRNA expression levels, miR-25, miR-106b, miR-326, and miR-93 were significantly upregulated, while miR-146a and miR-155 levels were lower in PBMCs of patients with BD" circulation_biomarker_diagnosis_up hsa-mir-93 Behcet Disease 30317557 "T-cell-associated miRNA expression levels, miR-25, miR-106b, miR-326, and miR-93 were significantly upregulated, while miR-146a and miR-155 levels were lower in PBMCs of patients with BD" circulation_biomarker_diagnosis_up hsa-mir-339 Amyloidosis 30332417 MiR-339-3p was increased in blood of patients with senile cardiac amyloidosis circulation_biomarker_diagnosis-down hsa-mir-181b Obesity 30160046 Pilot study on circulating miRNA signature in children with obesity born small for gestational age and appropriate for gestational age. circulation_biomarker_prognosis_down hsa-mir-326 Multiple Sclerosis 25642434 "Our longitudinal analysis revealed that miR-18a, miR-20b, miR-29a, and miR-103 were upregulated and predominantly expressed by CD4(+) T cells, whereas miR-326 was downregulated upon natalizumab treatment." circulation_biomarker_prognosis_down hsa-let-7a-1 Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. circulation_biomarker_prognosis_down hsa-let-7a-2 Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. circulation_biomarker_prognosis_down hsa-let-7a-3 Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. circulation_biomarker_prognosis_down hsa-let-7b Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. circulation_biomarker_prognosis_down hsa-let-7c Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. circulation_biomarker_prognosis_down hsa-let-7d Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. circulation_biomarker_prognosis_down hsa-let-7e Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. circulation_biomarker_prognosis_down hsa-let-7f-1 Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. circulation_biomarker_prognosis_down hsa-let-7f-2 Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. circulation_biomarker_prognosis_down hsa-let-7g Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. circulation_biomarker_prognosis_down hsa-let-7i Lung Neoplasms 17940623 Studies by Takamizawa et al. and Yanaihara et al. have presented evidence that transcripts of certain let-7 homologs are significantly downregulated in human lung cancer and that low levels of let-7 correlate with poor prognosis. circulation_biomarker_prognosis_down hsa-mir-9-1 Waldenstrom Macroglobulinemia 19074725 miR-9*: decreased expression circulation_biomarker_prognosis_down hsa-mir-9-2 Waldenstrom Macroglobulinemia 19074725 miR-9*: decreased expression circulation_biomarker_prognosis_down hsa-mir-9-3 Waldenstrom Macroglobulinemia 19074725 miR-9*: decreased expression circulation_biomarker_prognosis_down hsa-mir-195 Breast Neoplasms 20134314 circulating levels of miR-195 and let-7a decreased in cancer patients postoperatively circulation_biomarker_prognosis_down hsa-mir-296 Colon Neoplasms 22892953 Decrease in blood miR-296 predicts chemotherapy resistance and poor clinical outcome in patients receiving systemic chemotherapy for metastatic colon cancer. circulation_biomarker_prognosis_down hsa-mir-100 Urinary Bladder Cancer 23173870 Reduced expression of microRNA-100 confers unfavorable prognosis in patients with bladder cancer circulation_biomarker_prognosis_down hsa-mir-150 Hypertension 23220912 Reduced miR-150 is Associated with Poor Survival in Pulmonary Arterial Hypertension circulation_biomarker_prognosis_down hsa-mir-129-1 "Lymphoma, Large B-Cell, Diffuse" 23463124 Low expression of microRNA-129-5p predicts poor clinical outcome in diffuse large B cell lymphoma (DLBCL) circulation_biomarker_prognosis_down hsa-mir-129-2 "Lymphoma, Large B-Cell, Diffuse" 23463124 Low expression of microRNA-129-5p predicts poor clinical outcome in diffuse large B cell lymphoma (DLBCL) circulation_biomarker_prognosis_down hsa-mir-100 "Carcinoma, Hepatocellular" 23842624 Downregulation of microRNA-100 correlates with tumor progression and poor prognosis in hepatocellular carcinoma. circulation_biomarker_prognosis_down hsa-mir-150 Myocardial Infarction 23967079 "We enrolled 150 patients after AMI. Blood samples were obtained at discharge for determination of N-terminal pro-brain natriuretic peptide (Nt-proBNP) and levels of miR-16, miR-27a, miR-101 and miR-150." circulation_biomarker_prognosis_down hsa-mir-124-1 "Leukemia, Myeloid, Acute" 24135052 These findings suggest that miR-124-1 underexpression is a common event and might have a favorable impact on prognosis in AML. circulation_biomarker_prognosis_down hsa-mir-34a Gastric Neoplasms 24232982 "Decreased miR-34a expression and increased FOXP1, p53, and BCL2 coexpression to predict a poor OS for MALT lymphoma and DLBCL patients could become very important prognostic markers in daily clinical work. Further investigation of these changes may be of prognostic significance in clinical practice." circulation_biomarker_prognosis_down hsa-mir-146b "Lymphoma, Large B-Cell, Diffuse" 24931464 "Low expression of microRNA-146b-5p and microRNA-320d predicts poor outcome of large B-cell lymphoma treated with cyclophosphamide, doxorubicin, vincristine,and prednisone." circulation_biomarker_prognosis_down hsa-mir-320d "Lymphoma, Large B-Cell, Diffuse" 24931464 "Low expression of microRNA-146b-5p and microRNA-320d predicts poor outcome of large B-cell lymphoma treated with cyclophosphamide, doxorubicin, vincristine,and prednisone." circulation_biomarker_prognosis_down hsa-mir-19a Myeloma 25220540 Low serum miR-19a expression as a novel poor prognostic indicator in multiple myeloma. circulation_biomarker_prognosis_down hsa-let-7g "Squamous Cell Carcinoma, Head and Neck" 25677760 "decreased expressions of miR-153, miR-200c, miR-363, miR-203, miR-17, miR-205, miR-Let-7d, Let-7g, miR-34a, miR-126a, miR-375, miR-491-p5, miR 218, miR-451 and miR-125b were associated with poor prognosis." circulation_biomarker_prognosis_down hsa-mir-204 "Leukemia, Myeloid, Acute" 26126974 We showed low miR-204 expression in AML and found it to be an independent prognostic factor in this patient population. circulation_biomarker_prognosis_down hsa-mir-328 "Leukemia, Myeloid, Acute" 26185105 Low expression of circulating microRNA-328 is associated with poor prognosis in patients with acute myeloid leukemia. circulation_biomarker_prognosis_down hsa-mir-128 Prostate Neoplasms 26339409 "Our data suggest that the decreased expression of miR-128 in both tissue and serum samples of PCa patients may be associated with tumor malignant progression and BCR-free survival. Particularly, serum miR-128 may be developed as a novel noninvasive biomarker for PCa diagnosis and prognosis." circulation_biomarker_prognosis_down hsa-mir-153 "Carcinoma, Lung, Non-Small-Cell" 26339455 "Decreased expression of miR-153 might be a potential unfavorable prognostic factor for patients with NSCLC, and further studies would be needed to prove our findings." circulation_biomarker_prognosis_down hsa-mir-17 Preeclampsia 26339600 "ur data indicate that short-term exposure of 3A villous first trimester trophoblasts to H2O2 significantly alters miRNA profile and mRNA expression of genes implicated in defective placental development. Our data, which indicate that oxidative stress alters miRNAs and RNAs expression, could partially explain some of the early changes in gene expression profiles and miRNA observed in PE." circulation_biomarker_prognosis_down hsa-mir-204 "Carcinoma, Lung, Non-Small-Cell" 26497897 Decreased expression of miR-204 in plasma is associated with a poor prognosis in patients with non-small cell lung cancer. circulation_biomarker_prognosis_down hsa-mir-1 "Carcinoma, Hepatocellular" 26554254 Low miR-1 expression is associated with shortened survival time.MiR-1 may act as a potential prognostic biomarker for HCC patients. circulation_biomarker_prognosis_down hsa-mir-1 Acute Heart Failure 26580972 admission levels of miR-1 were lower in AHF and stable CHF patients compared to non-AHF patients circulation_biomarker_prognosis_down hsa-mir-218 "Carcinoma, Hepatocellular" 26586116 "Consequently, our findings revealed that serum miR-218 levels were remarkably underexpressed in HCC patients as compared to BLD patients and healthy controls." circulation_biomarker_prognosis_down hsa-mir-100 Bladder Neoplasms 26662386 "The present study demonstrated that the downregulation of miR-100 was associated with advanced clinical features and poor prognosis for bladder cancer patients, suggesting that miR-100 downregulation may be used as an unfavorable prognostic biomarker in bladder cancer." circulation_biomarker_prognosis_down hsa-mir-215 "Leukemia, Myeloid, Acute" 26802165 Our study demonstrates that reduced microRNA-215 expression is a common event and is associated with poor clinical outcome in acute myeloid leukemia. circulation_biomarker_prognosis_down hsa-mir-16 Colorectal Carcinoma 26934556 Serum miR-16 levels were significantly lower in the high blood glucose patients circulation_biomarker_prognosis_down hsa-mir-199a Ovarian Neoplasms 26951510 Expression of miR-199a was found to be significantly downregulated in comparison with matched normal controls. circulation_biomarker_prognosis_down hsa-mir-200a Choriocarcinoma 27081702 "Eleven miRNAs were significantly different between R and NR (miR-154, miR-409-3p, miR-127-3p, miR-214*, miR-299-5p and miR-125b overexpressed in NR; miR-33a, miR-30e, miR-338-3p, miR-200a and miR-378 decreased)." circulation_biomarker_prognosis_down hsa-mir-34a "Adenocarcinoma, Pancreatic Ductal" 27458977 "A loss of expression of miR-34a, but not of miR-150, is associated with disease progression and poor prognosis in PDAC patients, and may be involved in the chemoresistance of PDAC cells." circulation_biomarker_prognosis_down hsa-mir-145 "Carcinoma, Gastric" 27460730 "MiR-145-5p is down-expressed in GC, and can be used as a marker of poor prognosis in GC patients." circulation_biomarker_prognosis_down hsa-mir-1300 "Carcinoma, Colon" 27485175 Low expression of miR-1300 and miR-939 was significantly correlated with shorter distant metastasis-free survival (DMFS) in Cox univariate analysis (p.adjusted = 0.049). circulation_biomarker_prognosis_down hsa-mir-939 "Carcinoma, Colon" 27485175 Low expression of miR-1300 and miR-939 was significantly correlated with shorter distant metastasis-free survival (DMFS) in Cox univariate analysis (p.adjusted = 0.049). circulation_biomarker_prognosis_down hsa-mir-126 Arteriosclerosis Obliterans 27497911 "Furthermore, plasma miR-126-5p levels were significantly down-regulated in CAD patients with multi-vessel disease, higher SYNTAX score, rather than isolated LMCA and low SYNTAX score." circulation_biomarker_prognosis_down hsa-mir-126 Coronary Artery Disease 27497911 "Furthermore, plasma miR-126-5p levels were significantly down-regulated in CAD patients with multi-vessel disease, higher SYNTAX score, rather than isolated LMCA and low SYNTAX score." circulation_biomarker_prognosis_down hsa-mir-126 Myocardial Infarction 27497911 "Furthermore, plasma miR-126-5p levels were significantly down-regulated in CAD patients with multi-vessel disease, higher SYNTAX score, rather than isolated LMCA and low SYNTAX score." circulation_biomarker_prognosis_down hsa-mir-30c "Carcinoma, Lung, Non-Small-Cell" 27506865 MiR-30c-2* negative regulated MTA-1 expression involved in metastasis and drug resistance of HPV-infected non-small cell lung cancer. circulation_biomarker_prognosis_down hsa-mir-30c Human Papilloma Virus Infection 27506865 MiR-30c-2* negative regulated MTA-1 expression involved in metastasis and drug resistance of HPV-infected non-small cell lung cancer. circulation_biomarker_prognosis_down hsa-mir-29c "Carcinoma, Hepatocellular" 27525839 Our findings demonstrate that miR-29c expression is significantly downregulated in HCC patients and that miR-29c can act as an independent predictor of unfavorable clinical outcome. circulation_biomarker_prognosis_down hsa-mir-135a "Carcinoma, Lung, Non-Small-Cell" 27525941 "the serum miR-135a level was downregulated in NSCLC patients, and was associated with poor prognosis." circulation_biomarker_prognosis_down hsa-mir-148a Gastric Neoplasms 27529338 Down-regulation of miR-26a and miR-148a was significantly associated with shorter OS of GC patients circulation_biomarker_prognosis_down hsa-mir-26a Gastric Neoplasms 27529338 Down-regulation of miR-26a and miR-148a was significantly associated with shorter OS of GC patients circulation_biomarker_prognosis_down hsa-mir-218 Neoplasms [unspecific] 27631228 Prognostic significance of low microRNA-218 expression in patients with different types of cancer: Evidence from published studies. circulation_biomarker_prognosis_down hsa-mir-99a "Carcinoma, Breast" 27706621 Low levels of serum miR-99a is a predictor of poor prognosis in breast cancer. circulation_biomarker_prognosis_down hsa-mir-146a Coronary Artery Disease 28050558 Reduced Plasma miR-146a Is a Predictor of Poor Coronary Collateral Circulation in Patients with Coronary Artery Disease. circulation_biomarker_prognosis_down hsa-let-7i "Leukemia, Myeloid, Chronic" 28512058 Downregulation of miR-224 and let-7i contribute to cell survival and chemoresistance in chronic myeloid leukemia cells by regulating ST3GAL IV expression. circulation_biomarker_prognosis_down hsa-mir-224 "Leukemia, Myeloid, Chronic" 28512058 Downregulation of miR-224 and let-7i contribute to cell survival and chemoresistance in chronic myeloid leukemia cells by regulating ST3GAL IV expression. circulation_biomarker_prognosis_down hsa-mir-19a Breast Neoplasms 29189128 "up-regulation of miR181b, miR-34a, miR-16, miR-15a and miR-146b-5p, and down-regulation of miR-19a and miR-19b have been shown following the treatment of several breast cancer cell lines with curcumin" circulation_biomarker_prognosis_down hsa-mir-19b Breast Neoplasms 29189128 "up-regulation of miR181b, miR-34a, miR-16, miR-15a and miR-146b-5p, and down-regulation of miR-19a and miR-19b have been shown following the treatment of several breast cancer cell lines with curcumin" circulation_biomarker_prognosis_down hsa-mir-122 "Leukemia, Myeloid, Acute" 29627222 Lower expression of bone marrow miR-122 is an independent risk factor for overall survival in cytogenetically normal acute myeloid leukemia. circulation_biomarker_prognosis_down hsa-mir-21 Atrial Fibrillation 29676832 "The miRNAs had different expression profiles dependent on the AF condition, with higher expression in the acute new-onset AF than well-controlled AF" circulation_biomarker_prognosis_down hsa-mir-451 "Carcinoma, Breast" 30099860 "baseline miR-222 overexpression, C2 miR-20a up-regulation and C2 miR-451 down-regulation were predictive markers of response to NCT in HR+/HER2- breast cancer" circulation_biomarker_prognosis_down hsa-mir-146a Osteoarthritis 30105874 "Circulating miRNA expression profiles act as important roles in knee OA patients underwent celecoxib treatment, and miR-126-5p, miR-320a as well as miR-146a-5p might correlate with treatment response to celecoxib" circulation_biomarker_prognosis_down hsa-mir-130b "Carcinoma, Breast" 30109140 "postoperatively downregulated circulating miR-130b-5p, miR-151a-5p, miR-206, and miR-222-3p may be potential biomarkers for breast cancer diagnosis and prognosis" circulation_biomarker_prognosis_down hsa-mir-151a "Carcinoma, Breast" 30109140 "postoperatively downregulated circulating miR-130b-5p, miR-151a-5p, miR-206, and miR-222-3p may be potential biomarkers for breast cancer diagnosis and prognosis" circulation_biomarker_prognosis_down hsa-mir-206 "Carcinoma, Breast" 30109140 "postoperatively downregulated circulating miR-130b-5p, miR-151a-5p, miR-206, and miR-222-3p may be potential biomarkers for breast cancer diagnosis and prognosis" circulation_biomarker_prognosis_down hsa-mir-222 "Carcinoma, Breast" 30109140 "postoperatively downregulated circulating miR-130b-5p, miR-151a-5p, miR-206, and miR-222-3p may be potential biomarkers for breast cancer diagnosis and prognosis" circulation_biomarker_prognosis_down hsa-mir-146a "Leukemia, Myeloid, Acute" 30242879 "the high expression of hsa-miR-509 and hsa-miR-542 were independent poor prognostic factors, whereas that of hsa-miR-146a and hsa-miR-3667 had a trend to be favorable factors" circulation_biomarker_prognosis_down hsa-mir-3667 "Leukemia, Myeloid, Acute" 30242879 "the high expression of hsa-miR-509 and hsa-miR-542 were independent poor prognostic factors, whereas that of hsa-miR-146a and hsa-miR-3667 had a trend to be favorable factors" circulation_biomarker_prognosis_ns hsa-mir-1 Chronic Hepatitis C 21070682 "The main aim of this study was to evaluate the expression of several miRNAs (miR-1, miR-30, miR-128, miR-196, miR-296) in peripheral blood mononuclear cells (PBMCs) from healthy individuals after in vitro IFN-treatment and in PBMCs from patients with chronic hepatitis C (CHC) before and 12 hours after the first injection of pegylated IFN alpha" circulation_biomarker_prognosis_ns hsa-mir-128 Chronic Hepatitis C 21070682 "The main aim of this study was to evaluate the expression of several miRNAs (miR-1, miR-30, miR-128, miR-196, miR-296) in peripheral blood mononuclear cells (PBMCs) from healthy individuals after in vitro IFN-treatment and in PBMCs from patients with chronic hepatitis C (CHC) before and 12 hours after the first injection of pegylated IFN alpha" circulation_biomarker_prognosis_ns hsa-mir-196 Chronic Hepatitis C 21070682 "The main aim of this study was to evaluate the expression of several miRNAs (miR-1, miR-30, miR-128, miR-196, miR-296) in peripheral blood mononuclear cells (PBMCs) from healthy individuals after in vitro IFN-treatment and in PBMCs from patients with chronic hepatitis C (CHC) before and 12 hours after the first injection of pegylated IFN alpha" circulation_biomarker_prognosis_ns hsa-mir-296 Chronic Hepatitis C 21070682 "The main aim of this study was to evaluate the expression of several miRNAs (miR-1, miR-30, miR-128, miR-196, miR-296) in peripheral blood mononuclear cells (PBMCs) from healthy individuals after in vitro IFN-treatment and in PBMCs from patients with chronic hepatitis C (CHC) before and 12 hours after the first injection of pegylated IFN alpha" circulation_biomarker_prognosis_ns hsa-mir-30 Chronic Hepatitis C 21070682 "The main aim of this study was to evaluate the expression of several miRNAs (miR-1, miR-30, miR-128, miR-196, miR-296) in peripheral blood mononuclear cells (PBMCs) from healthy individuals after in vitro IFN-treatment and in PBMCs from patients with chronic hepatitis C (CHC) before and 12 hours after the first injection of pegylated IFN alpha" circulation_biomarker_prognosis_ns hsa-mir-126 Vascular Disease [unspecific] 23386708 plasma;Aspirin treatment hampers the use of plasma microRNA-126 as a biomarker for the progression of vascular disease circulation_biomarker_prognosis_ns hsa-mir-103 Prostate Neoplasms 24583788 Serum microRNA expression patterns that predict early treatment failure in prostate cancer patients. circulation_biomarker_prognosis_ns hsa-mir-125b Prostate Neoplasms 24583788 Serum microRNA expression patterns that predict early treatment failure in prostate cancer patients. circulation_biomarker_prognosis_ns hsa-mir-222 Prostate Neoplasms 24583788 Serum microRNA expression patterns that predict early treatment failure in prostate cancer patients. circulation_biomarker_prognosis_ns hsa-mir-103 Colorectal Carcinoma 26271186 Variability in microRNA recovery from plasma: Comparison of five commercial kits. circulation_biomarker_prognosis_ns hsa-mir-18a Colorectal Carcinoma 26271186 Variability in microRNA recovery from plasma: Comparison of five commercial kits. circulation_biomarker_prognosis_ns hsa-mir-191 Colorectal Carcinoma 26271186 Variability in microRNA recovery from plasma: Comparison of five commercial kits. circulation_biomarker_prognosis_ns hsa-mir-21 Colorectal Carcinoma 26271186 Variability in microRNA recovery from plasma: Comparison of five commercial kits. circulation_biomarker_prognosis_ns hsa-mir-23a Colorectal Carcinoma 26271186 Variability in microRNA recovery from plasma: Comparison of five commercial kits. circulation_biomarker_prognosis_ns hsa-mir-29a Colorectal Carcinoma 26271186 Variability in microRNA recovery from plasma: Comparison of five commercial kits. circulation_biomarker_prognosis_ns hsa-mir-451 Colorectal Carcinoma 26271186 Variability in microRNA recovery from plasma: Comparison of five commercial kits. circulation_biomarker_prognosis_ns hsa-mir-34a "Carcinoma, Breast" 28178621 Changes of serum miR34a expression during neoadjuvant chemotherapy predict the treatment response and prognosis in stage II/III breast cancer. circulation_biomarker_prognosis_ns hsa-mir-22 Atherosclerosis 28301500 Circulating progenitor cells in hypertensive subjects: Effectiveness of a treatment with olmesartan in improving cell number and miR profile in addition to expected pharmacological effects. circulation_biomarker_prognosis_ns hsa-mir-221 Atherosclerosis 28301500 Circulating progenitor cells in hypertensive subjects: Effectiveness of a treatment with olmesartan in improving cell number and miR profile in addition to expected pharmacological effects. circulation_biomarker_prognosis_ns hsa-mir-222 Atherosclerosis 28301500 Circulating progenitor cells in hypertensive subjects: Effectiveness of a treatment with olmesartan in improving cell number and miR profile in addition to expected pharmacological effects. circulation_biomarker_prognosis_ns hsa-mir-145 Chronic Hepatitis 28368488 Plasma MicroRNA Levels Are Associated With Hepatitis B e Antigen Status and Treatment Response in Chronic Hepatitis B Patients. circulation_biomarker_prognosis_ns hsa-mir-126 Atherosclerosis 28785651 Circulating level of microRNA-126 may be a potential biomarker for recovery from smoking-related vascular damage in middle-aged habitual smokers. circulation_biomarker_prognosis_ns hsa-mir-208 Viral Myocarditis 29916103 "Circulating MicroRNAs: a Potential Biomarker for Cardiac Damage, Inflammatory Response, and Left Ventricular Function Recovery in Pediatric Viral Myocarditis." circulation_biomarker_prognosis_ns hsa-mir-21 Viral Myocarditis 29916103 "Circulating MicroRNAs: a Potential Biomarker for Cardiac Damage, Inflammatory Response, and Left Ventricular Function Recovery in Pediatric Viral Myocarditis." circulation_biomarker_prognosis_ns hsa-mir-125b Chronic Hepatitis B 30344656 Baseline serum miR-125b levels predict virologic response to nucleos(t)ide analogue treatment in patients with HBeAg-positive chronic hepatitis B. circulation_biomarker_prognosis_ns hsa-let-7a-1 Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients circulation_biomarker_prognosis_ns hsa-let-7a-2 Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients circulation_biomarker_prognosis_ns hsa-let-7a-3 Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients circulation_biomarker_prognosis_ns hsa-let-7b Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients circulation_biomarker_prognosis_ns hsa-let-7c Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients circulation_biomarker_prognosis_ns hsa-let-7d Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients circulation_biomarker_prognosis_ns hsa-let-7e Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients circulation_biomarker_prognosis_ns hsa-let-7f-1 Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients circulation_biomarker_prognosis_ns hsa-let-7f-2 Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients circulation_biomarker_prognosis_ns hsa-let-7g Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients circulation_biomarker_prognosis_ns hsa-let-7i Lung Neoplasms 16885332 let-7a-1 expression correlates with poor survival of lung cancer patients circulation_biomarker_prognosis_ns hsa-mir-16 Leukemia 19195700 Prognostic value of miR-16 expression in childhood acute lymphoblastic leukemia relationships to normal and malignant lymphocyte proliferation. circulation_biomarker_prognosis_ns hsa-mir-181a-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 20487546 "miR-181a:Differential expression of the sulfatase SULF2 and of miR-29a, -181a, and -221 was also observed between resistant and sensitive patients before treatment" circulation_biomarker_prognosis_ns hsa-mir-221 "Leukemia, Lymphocytic, Chronic, B-Cell" 20487546 "miR-221:Differential expression of the sulfatase SULF2 and of miR-29a, -181a, and -221 was also observed between resistant and sensitive patients before treatment" circulation_biomarker_prognosis_ns hsa-mir-29a "Leukemia, Lymphocytic, Chronic, B-Cell" 20487546 "miR-29a:Differential expression of the sulfatase SULF2 and of miR-29a, -181a, and -221 was also observed between resistant and sensitive patients before treatment" circulation_biomarker_prognosis_ns hsa-mir-92a-1 Leukemia 21182798 The miR-92a expression in leukemia cells could be a prognostic factor in ALL patients circulation_biomarker_prognosis_ns hsa-mir-92a-2 Leukemia 21182798 The miR-92a expression in leukemia cells could be a prognostic factor in ALL patients circulation_biomarker_prognosis_ns hsa-let-7a-1 Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-let-7a-2 Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-let-7a-3 Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-let-7b Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-let-7c Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-let-7d Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-let-7e Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-let-7f-1 Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-let-7f-2 Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-let-7g Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-let-7i Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-mir-181a-1 Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-mir-181a-2 Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-mir-181b-2 Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-mir-181c Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-mir-181d Myelodysplastic Syndromes 21332710 dysregulated circulation_biomarker_prognosis_ns hsa-let-7a-1 Ovarian Neoplasms 21571355 let-7a is a potential marker for selection of paclitaxel in ovarian cancer management. circulation_biomarker_prognosis_ns hsa-mir-155 Leukemia 22209839 "These results support that miR-128, let-7b, miR-223 and miR181a have a diagnosis value in AL, while miR-181a and miR-155 are of great prognostic significance in AML." circulation_biomarker_prognosis_ns hsa-mir-181a Leukemia 22209839 "These results support that miR-128, let-7b, miR-223 and miR181a have a diagnosis value in AL, while miR-181a and miR-155 are of great prognostic significance in AML." circulation_biomarker_prognosis_ns hsa-mir-17 Gastric Neoplasms 22406928 The concentrations of plasma miR-17-5p/20a were significantly associated with the differentiation status and TNM stages of gastric cancer. Kaplan-Meier curve analysis revealed that high expression levels of miR-17-5p/20a were significantly correlated with poor overall survival. Cox regression analysis demonstrated that the level of plasma miR-20a was an independent risk predictor for prognosis. circulation_biomarker_prognosis_ns hsa-mir-20a Gastric Neoplasms 22406928 The concentrations of plasma miR-17-5p/20a were significantly associated with the differentiation status and TNM stages of gastric cancer. Kaplan-Meier curve analysis revealed that high expression levels of miR-17-5p/20a were significantly correlated with poor overall survival. Cox regression analysis demonstrated that the level of plasma miR-20a was an independent risk predictor for prognosis. circulation_biomarker_prognosis_ns hsa-mir-21 Esophageal Neoplasms 22519435 Circulating miR-21 and miR-375 could be reliable prognostic markers for ESCC. circulation_biomarker_prognosis_ns hsa-mir-375 Esophageal Neoplasms 22519435 Circulating miR-21 and miR-375 could be reliable prognostic markers for ESCC. circulation_biomarker_prognosis_ns hsa-mir-125b-1 "Carcinoma, Lung, Non-Small-Cell" 22806310 Circulating miR-125b is a novel biomarker for screening non-small-cell lung cancer and predicts poor prognosis. circulation_biomarker_prognosis_ns hsa-mir-125b-2 "Carcinoma, Lung, Non-Small-Cell" 22806310 Circulating miR-125b is a novel biomarker for screening non-small-cell lung cancer and predicts poor prognosis. circulation_biomarker_prognosis_ns hsa-mir-223 "Lymphoma, Large B-Cell, Diffuse" 22932402 "As a potential prognostic biomarker, overexpression of miR-223 correlates with a longer OS of patients with DLBCL (diffuse large B cell lymphoma)." circulation_biomarker_prognosis_ns hsa-mir-150 "Lymphoma, B-Cell" 22936066 miR-155 and miR-150 expression levels were associated with progression-free survival . circulation_biomarker_prognosis_ns hsa-mir-155 "Lymphoma, B-Cell" 22936066 miR-155 and miR-150 expression levels were associated with progression-free survival . circulation_biomarker_prognosis_ns hsa-mir-133a-1 Myocardial Infarction 23137501 Relation of circulating MicroRNA-133a concentrations with myocardial damage and clinical prognosis in ST-elevation myocardial infarction circulation_biomarker_prognosis_ns hsa-mir-133a-2 Myocardial Infarction 23137501 Relation of circulating MicroRNA-133a concentrations with myocardial damage and clinical prognosis in ST-elevation myocardial infarction circulation_biomarker_prognosis_ns hsa-mir-15a Ischemia 23233752 MicroRNA-15a and MicroRNA-16 Impair Human Circulating Proangiogenic Cell Functions and Are Increased in the Proangiogenic Cells and Serum of Patients With Critical Limb Ischemia circulation_biomarker_prognosis_ns hsa-mir-16-1 "Leukemia-Lymphoma, Adult T-Cell" 23260326 Micro-RNA-16 expression in paraffin-embedded specimen correlates with overall survival of T-lymphoblastic lymphoma/leukemia circulation_biomarker_prognosis_ns hsa-mir-16-2 "Leukemia-Lymphoma, Adult T-Cell" 23260326 Micro-RNA-16 expression in paraffin-embedded specimen correlates with overall survival of T-lymphoblastic lymphoma/leukemia circulation_biomarker_prognosis_ns hsa-mir-21 Osteosarcoma 23321165 Identification of Serum MicroRNA-21 as a Biomarker for Chemosensitivity and Prognosis in Human Osteosarcoma circulation_biomarker_prognosis_ns hsa-mir-126 Cardiovascular Diseases [unspecific] 23391580 "Platelets, endothelium, and circulating microRNA-126 as a prognostic biomarker in cardiovascular diseases: per aspirin ad astra." circulation_biomarker_prognosis_ns hsa-mir-16-1 "Carcinoma, Lung, Non-Small-Cell" 23774211 MiR-16 exhibited the most statistically significant association: high expression of miR-16 was associated with a significantly better survival circulation_biomarker_prognosis_ns hsa-mir-22 "Carcinoma, Lung, Non-Small-Cell" 23794259 "Circulating miR-22, miR-24 and miR-34a as novel predictive biomarkers to pemetrexed-based chemotherapy in advanced non-small cell lung cancer." circulation_biomarker_prognosis_ns hsa-mir-24 "Carcinoma, Lung, Non-Small-Cell" 23794259 "Circulating miR-22, miR-24 and miR-34a as novel predictive biomarkers to pemetrexed-based chemotherapy in advanced non-small cell lung cancer." circulation_biomarker_prognosis_ns hsa-mir-34a "Carcinoma, Lung, Non-Small-Cell" 23794259 "Circulating miR-22, miR-24 and miR-34a as novel predictive biomarkers to pemetrexed-based chemotherapy in advanced non-small cell lung cancer." circulation_biomarker_prognosis_ns hsa-let-7 Prostate Neoplasms 23798998 Distinct microRNA expression profile in prostate cancer patients with early clinical failure and the impact of let-7 as prognostic marker in high-risk prostate cancer. circulation_biomarker_prognosis_ns hsa-mir-155 Idiopathic Pulmonary Fibrosis 23822889 "These findings suggest that serum miR-21 is associated with IPF and the degree of damage indicated by FVC and radiologic examinations could correlate with miR-21 and miR-155 expression in serum. From another perspective, our study confirmed serum miRNA can be stable and detectable in serum of patients with IPF,which could prove useful as it could be considered as a new biomarker in serum for diagnosis and assessment of prognosis of IPF in the future." circulation_biomarker_prognosis_ns hsa-mir-21 Idiopathic Pulmonary Fibrosis 23822889 "These findings suggest that serum miR-21 is associated with IPF and the degree of damage indicated by FVC and radiologic examinations could correlate with miR-21 and miR-155 expression in serum. From another perspective, our study confirmed serum miRNA can be stable and detectable in serum of patients with IPF,which could prove useful as it could be considered as a new biomarker in serum for diagnosis and assessment of prognosis of IPF in the future." circulation_biomarker_prognosis_ns hsa-mir-21 Central Nervous System Embryonal Tumor 23832112 Serum miR-21 is a diagnostic and prognostic marker of primary central nervous system lymphoma. circulation_biomarker_prognosis_ns hsa-mir-200c "Carcinoma, Esophageal" 23838916 The serum level of miR-200c can be useful for predicting the response to chemotherapy and the prognosis of patients with esophageal cancer who receive neoadjuvant chemotherapy. circulation_biomarker_prognosis_ns hsa-mir-21 Colorectal Carcinoma 23970420 "Our results suggest that circulating serum miR-21 is a promising prognostic tumour marker, and they highlight the potential clinical utility of miR-21 expression as a prognostic marker for CRC prognosis." circulation_biomarker_prognosis_ns hsa-mir-100 Gastric Neoplasms 23975664 Prognostic role of microRNA polymorphisms in advanced gastric cancer: a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). circulation_biomarker_prognosis_ns hsa-mir-200c Colorectal Carcinoma 23982750 Serum miR-200c is a novel prognostic and metastasis-predictive biomarker in patients with colorectal cancer. circulation_biomarker_prognosis_ns hsa-mir-21 Neoplasms [unspecific] 24076132 "Our findings suggest that circulating miR-21 may not suitable to be a diagnostic biomarker, but it has a prognostic value in patients with cancer." circulation_biomarker_prognosis_ns hsa-mir-149 Neoplasms [unspecific] 24180461 The regression analysis identified tumour stage and miR-31 and miR-149 expression as independently associated with tumour progression and tumour stage and miR-149 expression as independently associated with cancer-specific survival. circulation_biomarker_prognosis_ns hsa-let-7f Ovarian Neoplasms 24223734 Our findings indicate that plasma miR-205 and let-7f are biomarkers for ovarian cancer detection that complement CA-125; let-7f may be predictive of ovarian cancer prognosis. circulation_biomarker_prognosis_ns hsa-mir-31 "Adenocarcinoma, Pancreatic Ductal" 24289824 "In a cohort of 70 patients, the high expression of miR-21 (p=0.018, HR=2.610; 95% CI=1.179-5.777) and miR-31 (p=0.039, HR=2.735; 95% CI=1.317-6.426), the low expression of miR-375 (p=0.022, HR=2.337; 95% CI=1.431-5.066) were associated with poor overall survival following resection, independent of clinical covariates." circulation_biomarker_prognosis_ns hsa-mir-130 Colorectal Carcinoma 24304648 Circulating microRNA expressions in colorectal cancer as predictors of response to chemotherapy. circulation_biomarker_prognosis_ns hsa-mir-145 Colorectal Carcinoma 24304648 Circulating microRNA expressions in colorectal cancer as predictors of response to chemotherapy. circulation_biomarker_prognosis_ns hsa-mir-20a Colorectal Carcinoma 24304648 Circulating microRNA expressions in colorectal cancer as predictors of response to chemotherapy. circulation_biomarker_prognosis_ns hsa-mir-216 Colorectal Carcinoma 24304648 Circulating microRNA expressions in colorectal cancer as predictors of response to chemotherapy. circulation_biomarker_prognosis_ns hsa-mir-372 Colorectal Carcinoma 24304648 Circulating microRNA expressions in colorectal cancer as predictors of response to chemotherapy. circulation_biomarker_prognosis_ns hsa-mir-221 Neoplasms [unspecific] 24319365 Lack of significant association between plasma/serum miR-221 expression and poor survival of carcinoma: a meta analysis. circulation_biomarker_prognosis_ns hsa-mir-223 Intestinal Schistosomiasis 24330517 This study suggested that the circulating miR-223 could serve as a potential new biomarker for the detection of schistosome infection and the assessment of the response to chemotherapy. circulation_biomarker_prognosis_ns hsa-mir-223 "Squamous Cell Carcinoma, Esophageal" 24390317 "miR-25, miR-223, and miR-375 were abnormally expressed in ESCC tissues and sera. Serum miR-223 and miR-375 are potential prognostic biomarkers for ESCC." circulation_biomarker_prognosis_ns hsa-mir-25 "Squamous Cell Carcinoma, Esophageal" 24390317 "miR-25, miR-223, and miR-375 were abnormally expressed in ESCC tissues and sera. Serum miR-223 and miR-375 are potential prognostic biomarkers for ESCC." circulation_biomarker_prognosis_ns hsa-mir-375 "Squamous Cell Carcinoma, Esophageal" 24390317 "miR-25, miR-223, and miR-375 were abnormally expressed in ESCC tissues and sera. Serum miR-223 and miR-375 are potential prognostic biomarkers for ESCC." circulation_biomarker_prognosis_ns hsa-mir-16 Lymphoma 24447552 Significance of microRNA-16 and bcl-2 expression in T lymphoblastic lymphoma/leukemia and its relation with prognosis. circulation_biomarker_prognosis_ns hsa-mir-19a Colorectal Carcinoma 24460313 Serum miR-19a predicts resistance to FOLFOX chemotherapy in advanced colorectal cancer cases. circulation_biomarker_prognosis_ns hsa-mir-21 Gastric Neoplasms 24460332 Plasma post-operative miR-21 expression in the prognosis of gastric cancers. circulation_biomarker_prognosis_ns hsa-mir-499 Myocardial Infarction 24461971 Admission levels of circulating miR-499-5p and risk of death in elderly patients after acute non-ST elevation myocardial infarction. circulation_biomarker_prognosis_ns hsa-mir-146a "Carcinoma, Lung, Non-Small-Cell" 24531034 Serum levels of miR-19b and miR-146a as prognostic biomarkers for non-small cell lung cancer. circulation_biomarker_prognosis_ns hsa-mir-19b "Carcinoma, Lung, Non-Small-Cell" 24531034 Serum levels of miR-19b and miR-146a as prognostic biomarkers for non-small cell lung cancer. circulation_biomarker_prognosis_ns hsa-mir-103 "Carcinoma, Nasopharyngeal" 24563490 Differentially expressed plasma miRNAs as identified by next-generation sequencing can be helpful for predicting survival in NPC patients. circulation_biomarker_prognosis_ns hsa-mir-29a "Carcinoma, Nasopharyngeal" 24563490 Differentially expressed plasma miRNAs as identified by next-generation sequencing can be helpful for predicting survival in NPC patients. circulation_biomarker_prognosis_ns hsa-mir-483 "Carcinoma, Nasopharyngeal" 24563490 Differentially expressed plasma miRNAs as identified by next-generation sequencing can be helpful for predicting survival in NPC patients. circulation_biomarker_prognosis_ns hsa-mir-21 Neoplasms [unspecific] 24664585 The present meta-analysis suggests that circulating miR-21 expression is associated with poor survival in patients with cancer and could be a prognostic biomarker for those patients. circulation_biomarker_prognosis_ns hsa-mir-1236 "Lymphoma, Large B-Cell, Diffuse" 24858372 novel prognostic biomarkers to predict the clinical outcome of DLBCL patients treated with R-CHOP regimen. circulation_biomarker_prognosis_ns hsa-mir-224 "Lymphoma, Large B-Cell, Diffuse" 24858372 novel prognostic biomarkers to predict the clinical outcome of DLBCL patients treated with R-CHOP regimen. circulation_biomarker_prognosis_ns hsa-mir-33a "Lymphoma, Large B-Cell, Diffuse" 24858372 novel prognostic biomarkers to predict the clinical outcome of DLBCL patients treated with R-CHOP regimen. circulation_biomarker_prognosis_ns hsa-mir-455 "Lymphoma, Large B-Cell, Diffuse" 24858372 novel prognostic biomarkers to predict the clinical outcome of DLBCL patients treated with R-CHOP regimen. circulation_biomarker_prognosis_ns hsa-mir-520d "Lymphoma, Large B-Cell, Diffuse" 24858372 novel prognostic biomarkers to predict the clinical outcome of DLBCL patients treated with R-CHOP regimen. circulation_biomarker_prognosis_ns hsa-let-7c Breast Neoplasms 24866763 "Our identified mRNAs and microRNAs were validated as prognostic factors of BC disease progression, and could potentially facilitate the implementation of assays for laboratory validation, due to their reduced number." circulation_biomarker_prognosis_ns hsa-mir-139 Breast Neoplasms 24866763 "Our identified mRNAs and microRNAs were validated as prognostic factors of BC disease progression, and could potentially facilitate the implementation of assays for laboratory validation, due to their reduced number." circulation_biomarker_prognosis_ns hsa-mir-320d Breast Neoplasms 24866763 "Our identified mRNAs and microRNAs were validated as prognostic factors of BC disease progression, and could potentially facilitate the implementation of assays for laboratory validation, due to their reduced number." circulation_biomarker_prognosis_ns hsa-mir-567 Breast Neoplasms 24866763 "Our identified mRNAs and microRNAs were validated as prognostic factors of BC disease progression, and could potentially facilitate the implementation of assays for laboratory validation, due to their reduced number." circulation_biomarker_prognosis_ns hsa-mir-29a "Carcinoma, Lung, Non-Small-Cell" 24928469 "Ten miRNA's were significantly associated with OS, with hsa-miR-29a being the strongest prognostic marker (HR=6.44, 95%-CI 2.39-17.33)." circulation_biomarker_prognosis_ns hsa-mir-376a "Carcinoma, Lung, Non-Small-Cell" 24928469 "Six out of the 10 miRNA's (hsa-miRN-29a, hsa-miR-542-5p, hsa-miR-502-3p, hsa-miR-376a, hsa-miR-500a, hsa-miR-424) were insensitive to perturbations according to jackknife cross-validation on their HR for OS." circulation_biomarker_prognosis_ns hsa-mir-424 "Carcinoma, Lung, Non-Small-Cell" 24928469 "Six out of the 10 miRNA's (hsa-miRN-29a, hsa-miR-542-5p, hsa-miR-502-3p, hsa-miR-376a, hsa-miR-500a, hsa-miR-424) were insensitive to perturbations according to jackknife cross-validation on their HR for OS." circulation_biomarker_prognosis_ns hsa-mir-500a "Carcinoma, Lung, Non-Small-Cell" 24928469 "Six out of the 10 miRNA's (hsa-miRN-29a, hsa-miR-542-5p, hsa-miR-502-3p, hsa-miR-376a, hsa-miR-500a, hsa-miR-424) were insensitive to perturbations according to jackknife cross-validation on their HR for OS." circulation_biomarker_prognosis_ns hsa-mir-502 "Carcinoma, Lung, Non-Small-Cell" 24928469 "Six out of the 10 miRNA's (hsa-miRN-29a, hsa-miR-542-5p, hsa-miR-502-3p, hsa-miR-376a, hsa-miR-500a, hsa-miR-424) were insensitive to perturbations according to jackknife cross-validation on their HR for OS." circulation_biomarker_prognosis_ns hsa-mir-542 "Carcinoma, Lung, Non-Small-Cell" 24928469 "Six out of the 10 miRNA's (hsa-miRN-29a, hsa-miR-542-5p, hsa-miR-502-3p, hsa-miR-376a, hsa-miR-500a, hsa-miR-424) were insensitive to perturbations according to jackknife cross-validation on their HR for OS." circulation_biomarker_prognosis_ns hsa-mir-210 "Carcinoma, Hepatocellular" 24935355 Serum miR-210 may represent a novel biomarker for predicting efficacy of transarterial chemoembolization and overall survival for patients with HCC. circulation_biomarker_prognosis_ns hsa-let-7a Diabetes Mellitus 24937531 "Treatment-na?ve, poorly controlled diabetic patients show a significant dysregulation of miRNAs involved in the regulation of the adiponectin pathway, a phenomenon that may be reversed, at least in part, by improved glycemic control." circulation_biomarker_prognosis_ns hsa-mir-143 Colorectal Carcinoma 24940606 We identified miR-345 in whole blood as a potential biomarker for clinical outcome. MiR-345 was a single prognostic biomarker for both OS and PFS in all patients and also in the non-KRAS mutant population. circulation_biomarker_prognosis_ns hsa-mir-324 Colorectal Carcinoma 24940606 We identified miR-345 in whole blood as a potential biomarker for clinical outcome. MiR-345 was a single prognostic biomarker for both OS and PFS in all patients and also in the non-KRAS mutant population. circulation_biomarker_prognosis_ns hsa-mir-345 Colorectal Carcinoma 24940606 We identified miR-345 in whole blood as a potential biomarker for clinical outcome. MiR-345 was a single prognostic biomarker for both OS and PFS in all patients and also in the non-KRAS mutant population. circulation_biomarker_prognosis_ns hsa-mir-34a Colorectal Carcinoma 24940606 We identified miR-345 in whole blood as a potential biomarker for clinical outcome. MiR-345 was a single prognostic biomarker for both OS and PFS in all patients and also in the non-KRAS mutant population. circulation_biomarker_prognosis_ns hsa-mir-628 Colorectal Carcinoma 24940606 We identified miR-345 in whole blood as a potential biomarker for clinical outcome. MiR-345 was a single prognostic biomarker for both OS and PFS in all patients and also in the non-KRAS mutant population. circulation_biomarker_prognosis_ns hsa-mir-886 Colorectal Carcinoma 24940606 We identified miR-345 in whole blood as a potential biomarker for clinical outcome. MiR-345 was a single prognostic biomarker for both OS and PFS in all patients and also in the non-KRAS mutant population. circulation_biomarker_prognosis_ns hsa-mir-218 Gastric Neoplasms 24944481 "miR-218 is deregulated in gastric cancer patients and is strongly correlated with tumor stage, grade and metastasis. Serum expression of miR-218 may be a prognostic marker." circulation_biomarker_prognosis_ns hsa-mir-105 Pelvic Inflammatory Disease 24961692 Early microRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection. circulation_biomarker_prognosis_ns hsa-mir-132 Pelvic Inflammatory Disease 24961692 Early microRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection. circulation_biomarker_prognosis_ns hsa-mir-135a Pelvic Inflammatory Disease 24961692 Early microRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection. circulation_biomarker_prognosis_ns hsa-mir-142 Pelvic Inflammatory Disease 24961692 Early microRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection. circulation_biomarker_prognosis_ns hsa-mir-147 Pelvic Inflammatory Disease 24961692 Early microRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection. circulation_biomarker_prognosis_ns hsa-mir-155 Pelvic Inflammatory Disease 24961692 Early microRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection. circulation_biomarker_prognosis_ns hsa-mir-223 Pelvic Inflammatory Disease 24961692 Early microRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection. circulation_biomarker_prognosis_ns hsa-mir-298 Pelvic Inflammatory Disease 24961692 Early microRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection. circulation_biomarker_prognosis_ns hsa-mir-299a Pelvic Inflammatory Disease 24961692 Early microRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection. circulation_biomarker_prognosis_ns hsa-mir-325 Pelvic Inflammatory Disease 24961692 Early microRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection. circulation_biomarker_prognosis_ns hsa-mir-410 Pelvic Inflammatory Disease 24961692 Early microRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection. circulation_biomarker_prognosis_ns hsa-mir-202 Breast Neoplasms 24983365 "Based on their cancer-specific increase in breast cancer patients,circulating MAGE-A and BORIS mRNAs may be further explored for early detection of breast cancer and monitoring of MAGE-directed immunotherapies. Moreover, serum miR-202 is associated with prognosis." circulation_biomarker_prognosis_ns hsa-mir-224 "Lymphoma, Large B-Cell, Diffuse" 25052605 miR-224 expression may play an important role in the development and progression of DLBCL and could be prognostic significance. circulation_biomarker_prognosis_ns hsa-mir-21 Breast Neoplasms 25086636 "Changes in serum levels of miR-21, miR-210, and miR-373 in HER2-positive breast cancer patients undergoing neoadjuvant therapy" circulation_biomarker_prognosis_ns hsa-mir-210 Breast Neoplasms 25086636 "Changes in serum levels of miR-21, miR-210, and miR-373 in HER2-positive breast cancer patients undergoing neoadjuvant therapy" circulation_biomarker_prognosis_ns hsa-mir-373 Breast Neoplasms 25086636 "Changes in serum levels of miR-21, miR-210, and miR-373 in HER2-positive breast cancer patients undergoing neoadjuvant therapy" circulation_biomarker_prognosis_ns hsa-mir-133b Osteosarcoma 25120799 Serum levels of microRNA-133b and microRNA-206 expression predict prognosis in patients with osteosarcoma. circulation_biomarker_prognosis_ns hsa-mir-206 Osteosarcoma 25120799 Serum levels of microRNA-133b and microRNA-206 expression predict prognosis in patients with osteosarcoma. circulation_biomarker_prognosis_ns hsa-mir-19a Breast Neoplasms 25137071 The combination of miR-19a and miR-205 in the serum may predict the chemosensitivity of luminal A subtype of breast cancer to epirubicin plus paclitaxel neoadjuvant chemotherapy. circulation_biomarker_prognosis_ns hsa-mir-205 Breast Neoplasms 25137071 The combination of miR-19a and miR-205 in the serum may predict the chemosensitivity of luminal A subtype of breast cancer to epirubicin plus paclitaxel neoadjuvant chemotherapy. circulation_biomarker_prognosis_ns hsa-mir-146a "Leukemia, Promyelocytic, Acute" 25161335 These findings indicated that miR-146a played an important role in the development of APL in part through the repression on Smad4 protein expression. miR-146a functioned as an oncogene and may be a novel prognostic biomarker in APL. circulation_biomarker_prognosis_ns hsa-mir-454 Glioma 25190548 Plasma miR-454-3p as a potential prognostic indicator in human glioma. circulation_biomarker_prognosis_ns hsa-mir-145 "Adenocarcinoma, Lung" 25192889 miRNA-145 is strongly associated with overall survival circulation_biomarker_prognosis_ns hsa-mir-21 Glioma 25279461 "Moreover, in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses" circulation_biomarker_prognosis_ns hsa-mir-10b Breast Neoplasms 25369070 "Moreover, miR-10b, miR-21 and miR-182 were significantly associated to lymph node metastases occurrence in triple negative breast carcinoma while only miR-10b was associated with grade III in non triple negative breast cancer cases." circulation_biomarker_prognosis_ns hsa-mir-182 Breast Neoplasms 25369070 "Moreover, miR-10b, miR-21 and miR-182 were significantly associated to lymph node metastases occurrence in triple negative breast carcinoma" circulation_biomarker_prognosis_ns hsa-mir-221 Lymphoma 25430553 serum miR-221 expression level has prognostic value in patients with CMM. circulation_biomarker_prognosis_ns hsa-mir-155 Colorectal Carcinoma 25528214 the detection of miR-155 levels in the serum might serve as a new tumor biomarker in the diagnosis and assessment of prognosis of CRC. circulation_biomarker_prognosis_ns hsa-mir-15a Glioma 25575767 "the expression of miR-15a is significantly correlated with prognosis in glioma patients, suggesting that the miR-15a may serve as independent prognostic marker." circulation_biomarker_prognosis_ns hsa-mir-718 "Carcinoma, Hepatocellular" 25584485 Circulating miRs in serum exosomes have potential as novel biomarkers for predicting HCC recurrence. circulation_biomarker_prognosis_ns hsa-mir-150 "Leukemia, Lymphocytic, Chronic, B-Cell" 25584781 Cellular and serum levels of miR-150 are associated with opposite clinical prognoses and could be used to molecularly monitor disease evolution as a new prognostic factor in CLL. circulation_biomarker_prognosis_ns hsa-mir-224 Graves Ophthalmopathy 25588771 baseline serum miR-224-5p was associated with GC sensitivity in GO and in vitro overexpression of miR-224-5p restored GC sensitivity in a resistant cell model. A parameter combined serum miR-224-5p and TRAb could effectively predict GC ensitivity in GO patients. circulation_biomarker_prognosis_ns hsa-mir-106b Breast Neoplasms 25619461 "MiR-106b was found to be associated with a high risk of recurrence of breast cancer, and miR-106b is a putative plasma marker for risk assessment in patients with breast cancer." circulation_biomarker_prognosis_ns hsa-mir-141 Ovarian Neoplasms 25636451 miR-200c and miR-141 may be predictive biomarkers for ovarian cancer prognosis. Further large-scale studies are still needed to confirm our findings. circulation_biomarker_prognosis_ns hsa-mir-200c Ovarian Neoplasms 25636451 miR-200c and miR-141 may be predictive biomarkers for ovarian cancer prognosis. Further large-scale studies are still needed to confirm our findings. circulation_biomarker_prognosis_ns hsa-mir-128-2 "Carcinoma, Hepatocellular" 25642945 Serum miR-128-2 serves as a prognostic marker for patients with hepatocellular carcinoma. circulation_biomarker_prognosis_ns hsa-let-7i Colorectal Carcinoma 25663689 We discovered a metastasis-specific miRNA signature in pCRCs and discovered novel tissue- and serum-based CRC metastasis-specific miRNA biomarkers through intensive validation. These unique miRNAs may be clinically applicable to predict prognosis and distant metastasis in CRC. circulation_biomarker_prognosis_ns hsa-mir-10b Colorectal Carcinoma 25663689 We discovered a metastasis-specific miRNA signature in pCRCs and discovered novel tissue- and serum-based CRC metastasis-specific miRNA biomarkers through intensive validation. These unique miRNAs may be clinically applicable to predict prognosis and distant metastasis in CRC. circulation_biomarker_prognosis_ns hsa-mir-221 Colorectal Carcinoma 25663689 We discovered a metastasis-specific miRNA signature in pCRCs and discovered novel tissue- and serum-based CRC metastasis-specific miRNA biomarkers through intensive validation. These unique miRNAs may be clinically applicable to predict prognosis and distant metastasis in CRC. circulation_biomarker_prognosis_ns hsa-mir-320a Colorectal Carcinoma 25663689 We discovered a metastasis-specific miRNA signature in pCRCs and discovered novel tissue- and serum-based CRC metastasis-specific miRNA biomarkers through intensive validation. These unique miRNAs may be clinically applicable to predict prognosis and distant metastasis in CRC. circulation_biomarker_prognosis_ns hsa-mir-885 Colorectal Carcinoma 25663689 We discovered a metastasis-specific miRNA signature in pCRCs and discovered novel tissue- and serum-based CRC metastasis-specific miRNA biomarkers through intensive validation. These unique miRNAs may be clinically applicable to predict prognosis and distant metastasis in CRC. circulation_biomarker_prognosis_ns hsa-mir-122 Sepsis 25672224 Serum miR-122 correlates with short-term mortality in sepsis patients. circulation_biomarker_prognosis_ns hsa-mir-224 "Carcinoma, Hepatocellular" 25688365 Serum miR-224 might be BCLC stage dependent. It can reflect the status of tumor and liver damage. It was an independent predictor for the survival of HCC patients. circulation_biomarker_prognosis_ns hsa-mir-214 "Lymphoma, Large B-Cell, Diffuse" 25723320 Comprehensive miRNA sequence analysis reveals survival differences in diffuse large B-cell lymphoma patients circulation_biomarker_prognosis_ns hsa-mir-28 "Lymphoma, Large B-Cell, Diffuse" 25723320 Comprehensive miRNA sequence analysis reveals survival differences in diffuse large B-cell lymphoma patients circulation_biomarker_prognosis_ns hsa-mir-339 "Lymphoma, Large B-Cell, Diffuse" 25723320 Comprehensive miRNA sequence analysis reveals survival differences in diffuse large B-cell lymphoma patients circulation_biomarker_prognosis_ns hsa-mir-5586 "Lymphoma, Large B-Cell, Diffuse" 25723320 Comprehensive miRNA sequence analysis reveals survival differences in diffuse large B-cell lymphoma patients circulation_biomarker_prognosis_ns hsa-mir-210 "Adenocarcinoma, Lung" 25733977 "Significant correlations were found between miR-210 expression and lymph node metastasis, late disease stages, and poor prognosis in patients with adenocarcinoma." circulation_biomarker_prognosis_ns hsa-mir-210 Melanoma 25749524 A direct plasma assay of circulating microRNA-210 of hypoxia can identify early systemic metastasis recurrence in melanoma patients. circulation_biomarker_prognosis_ns hsa-mir-122 Hepatitis C Virus Infection 25811198 The expression levels of miR-21 and miR-122 were significantly different between the SVR and NR groups. circulation_biomarker_prognosis_ns hsa-mir-141 Breast Neoplasms 25885099 "Circulating miR-200c and miR-141 were deregulated in BC comparing with controls. Furthermore, miR-200c and miR-141 were independent prognostic factors and associated with distinct outcomes of BC patients." circulation_biomarker_prognosis_ns hsa-mir-200c Breast Neoplasms 25885099 "Circulating miR-200c and miR-141 were deregulated in BC comparing with controls. Furthermore, miR-200c and miR-141 were independent prognostic factors and associated with distinct outcomes of BC patients." circulation_biomarker_prognosis_ns hsa-mir-208a Breast Neoplasms 26046768 Circulating mir-208a fails as a biomarker of doxorubicin-induced cardiotoxicity in breast cancer patients. circulation_biomarker_prognosis_ns hsa-mir-200a Ovarian Neoplasms 26063644 "Our findings suggest that miR-200a, miR-200b, and miR-200c overexpressions are associated with the aggressive tumor progression and be recognized as reliable markers to predict the prognosis and survival in EOC patients." circulation_biomarker_prognosis_ns hsa-mir-200b Ovarian Neoplasms 26063644 "Our findings suggest that miR-200a, miR-200b, and miR-200c overexpressions are associated with the aggressive tumor progression and be recognized as reliable markers to predict the prognosis and survival in EOC patients." circulation_biomarker_prognosis_ns hsa-mir-200c Ovarian Neoplasms 26063644 "Our findings suggest that miR-200a, miR-200b, and miR-200c overexpressions are associated with the aggressive tumor progression and be recognized as reliable markers to predict the prognosis and survival in EOC patients." circulation_biomarker_prognosis_ns hsa-mir-21 Gastric Neoplasms 26063956 Circulating MicroRNA-21 Is a Potential Diagnostic Biomarker in Gastric Cancer. circulation_biomarker_prognosis_ns hsa-mir-197 Lung Neoplasms 26078336 Especially hsa-miR-197 could be validated by qRT-PCR as prognostic marker. circulation_biomarker_prognosis_ns hsa-mir-126 Intermittent Claudication 26116711 "Whole blood expression of pro-angiogenic microRNA-126 increased after maximal exercise in the PLA session, but treatment with NAC prevented this response." circulation_biomarker_prognosis_ns hsa-mir-10 "Leukemia, Myeloid, Acute" 26134365 Serum level of miR-10-5p as a prognostic biomarker for acute myeloid leukemia. circulation_biomarker_prognosis_ns hsa-mir-106a Colorectal Carcinoma 26250939 The present study reveals novel serum-miRNA-based biomarkers for monitoring tumor dynamics as well as for predicting disease recurrence in patients with stage II/III CRC. circulation_biomarker_prognosis_ns hsa-mir-145 Colorectal Carcinoma 26250939 The present study reveals novel serum-miRNA-based biomarkers for monitoring tumor dynamics as well as for predicting disease recurrence in patients with stage II/III CRC. circulation_biomarker_prognosis_ns hsa-mir-17 Colorectal Carcinoma 26250939 The present study reveals novel serum-miRNA-based biomarkers for monitoring tumor dynamics as well as for predicting disease recurrence in patients with stage II/III CRC. circulation_biomarker_prognosis_ns hsa-mir-101 Pleural Mesothelioma 26262875 "In conclusion, we suggest that miRNA signature A is predictive of sarcomatoid histotype and of worse prognosis in MPM." circulation_biomarker_prognosis_ns hsa-mir-191 Pleural Mesothelioma 26262875 "In conclusion, we suggest that miRNA signature A is predictive of sarcomatoid histotype and of worse prognosis in MPM." circulation_biomarker_prognosis_ns hsa-mir-223 Pleural Mesothelioma 26262875 "In conclusion, we suggest that miRNA signature A is predictive of sarcomatoid histotype and of worse prognosis in MPM." circulation_biomarker_prognosis_ns hsa-mir-25 Pleural Mesothelioma 26262875 "In conclusion, we suggest that miRNA signature A is predictive of sarcomatoid histotype and of worse prognosis in MPM." circulation_biomarker_prognosis_ns hsa-mir-26b Pleural Mesothelioma 26262875 "In conclusion, we suggest that miRNA signature A is predictive of sarcomatoid histotype and of worse prognosis in MPM." circulation_biomarker_prognosis_ns hsa-mir-29a Pleural Mesothelioma 26262875 "In conclusion, we suggest that miRNA signature A is predictive of sarcomatoid histotype and of worse prognosis in MPM." circulation_biomarker_prognosis_ns hsa-mir-335 Pleural Mesothelioma 26262875 "In conclusion, we suggest that miRNA signature A is predictive of sarcomatoid histotype and of worse prognosis in MPM." circulation_biomarker_prognosis_ns hsa-mir-433 Pleural Mesothelioma 26262875 "In conclusion, we suggest that miRNA signature A is predictive of sarcomatoid histotype and of worse prognosis in MPM." circulation_biomarker_prognosis_ns hsa-mir-516 Pleural Mesothelioma 26262875 "In conclusion, we suggest that miRNA signature A is predictive of sarcomatoid histotype and of worse prognosis in MPM." circulation_biomarker_prognosis_ns hsa-mir-224 Lymphoma 26301883 MiR-224 expression level is implicated as a prognostic marker for DLBCL patients treated with R-CHOP. circulation_biomarker_prognosis_ns hsa-mir-124 Toxic Epidermal Necrolysis 26394757 "The serum miR-124 concentration can be used as a disease activity marker for severe drug eruptions, reflecting the severity of keratinocyte apoptosis." circulation_biomarker_prognosis_ns hsa-mir-4728 Breast Neoplasms 26406406 MiR-4728-3p had better ability in distinguishing patients with different status of HER2 than miR-4728-5p. And plasma miR-4728-3p might act as a non-invasive biomarker in predicting HER2 status. circulation_biomarker_prognosis_ns hsa-mir-200c Malignant Neoplasms [unspecific] 26556949 "Our findings indicated that, compared to their tissue counterparts, the expression level of miR-200c and miR-141 in peripheral blood may be more effective for monitoring cancer prognosis. High miR-141 expression was better at predicting tumor progression than survival for malignant tumors." circulation_biomarker_prognosis_ns hsa-mir-122 Autoimmune Hepatitis 26575387 Alternations of miR-21 and miR-122 serum levels could reflect their putative roles in the mediation of inflammatory processes in AIH. circulation_biomarker_prognosis_ns hsa-mir-21 Autoimmune Hepatitis 26575387 Alternations of miR-21 and miR-122 serum levels could reflect their putative roles in the mediation of inflammatory processes in AIH. circulation_biomarker_prognosis_ns hsa-mir-200c Gastric Neoplasms 26662382 Serum miR-200c expression level as a prognostic biomarker for gastric cancer. circulation_biomarker_prognosis_ns hsa-mir-15a Sepsis 26683209 The plasma levels of miRNA are altered in patients with severe sepsis complicated by shock and may offer prognostic value as well as insights into the mechanisms of endothelial dysfunction in sepsis. circulation_biomarker_prognosis_ns hsa-mir-27a Sepsis 26683209 The plasma levels of miRNA are altered in patients with severe sepsis complicated by shock and may offer prognostic value as well as insights into the mechanisms of endothelial dysfunction in sepsis. circulation_biomarker_prognosis_ns hsa-mir-16 "Squamous Cell Carcinoma, Esophageal" 26692950 the level of miR-16 in the patients with good outcome was significantly higher than that in the patients with poor outcome circulation_biomarker_prognosis_ns hsa-mir-197 Coronary Artery Disease 26720041 Serum-derived circulating miRNA-197 and miRNA-223 were identified as predictors for cardiovascular death in a large patient cohort with CAD. These results reinforce the assumption that circulating miRNAs are promising biomarkers with prognostic value with respect to future cardiovascular events. circulation_biomarker_prognosis_ns hsa-mir-223 Coronary Artery Disease 26720041 Serum-derived circulating miRNA-197 and miRNA-223 were identified as predictors for cardiovascular death in a large patient cohort with CAD. These results reinforce the assumption that circulating miRNAs are promising biomarkers with prognostic value with respect to future cardiovascular events. circulation_biomarker_prognosis_ns hsa-mir-122 "Carcinoma, Hepatocellular" 27074850 "HCC and/or histological components of NASH affected serum miR-122 levels, independently." circulation_biomarker_prognosis_ns hsa-mir-455 "Squamous Cell Carcinoma, Head and Neck" 27109697 "miR-193b-3p and miR-455-5p were positively associated with survival, and miR-92a-3p and miR-497-5p were negatively associated with survival in OPSCC." circulation_biomarker_prognosis_ns hsa-let-7 Lung Neoplasms 27133539 Patients with a high level of baseline serum let-7 expression level had significantly better overall survival circulation_biomarker_prognosis_ns hsa-let-7 Chronic Hepatitis C 27227815 reduced levels of let-7a/7c/7d-5p (let-7s) in plasma were correlated with advanced histological hepatic fibrosis stage circulation_biomarker_prognosis_ns hsa-mir-29a Acquired Immunodeficiency Syndrome 27232693 the expression level of miR-29a was found to be inversely correlated with HIV viral load circulation_biomarker_prognosis_ns hsa-mir-29a Human Immunodeficiency Virus Infection 27232693 the expression level of miR-29a was found to be inversely correlated with HIV viral load circulation_biomarker_prognosis_ns hsa-mir-125b "Carcinoma, Hepatocellular" 27267832 serum miR-125b can serve as a biomarker to reliably predict microvascular invasion circulation_biomarker_prognosis_ns hsa-mir-181d Pancreatic Neoplasms 27380024 serum miR-181d was significantly associated with the presence of metastasis in patients with PDA circulation_biomarker_prognosis_ns hsa-mir-106b Ependymoma 27390862 "Three miRNAs were shown to efficiently differentiate between grade II and III ependymomas: miR-17-5p, miR-19a-3p, and miR-106b-5p." circulation_biomarker_prognosis_ns hsa-mir-196a Gastric Neoplasms 27420607 "Taken together, we propose that circulating miR-196a/b serve as a more sensitive and specific novel biomarker than carbohydrate antigen 19-9 for GC monitor, diagnosis and prognosis." circulation_biomarker_prognosis_ns hsa-mir-196b Gastric Neoplasms 27420607 "Taken together, we propose that circulating miR-196a/b serve as a more sensitive and specific novel biomarker than carbohydrate antigen 19-9 for GC monitor, diagnosis and prognosis." circulation_biomarker_prognosis_ns hsa-mir-484 "Carcinoma, Thyroid, Follicular" 27473101 The best two-miRNA classifier (miR-484/miR-148b-3p) identified thyroid malignancy with a sensitivity of 89â€? and a specificity of 87â€?. circulation_biomarker_prognosis_ns hsa-mir-1296 "Carcinoma, Colon" 27485175 "The expression signature of five miRNAs (miR-1296, miR-135b, miR-539, miR-572 and miR-185) was found to be prognostic [p = 1.28E-07, HR 8.4 (95 % CI: 3.81-18.52)] for DMFS" circulation_biomarker_prognosis_ns hsa-mir-135b "Carcinoma, Colon" 27485175 "The expression signature of five miRNAs (miR-1296, miR-135b, miR-539, miR-572 and miR-185) was found to be prognostic [p = 1.28E-07, HR 8.4 (95 % CI: 3.81-18.52)] for DMFS." circulation_biomarker_prognosis_ns hsa-mir-185 "Carcinoma, Colon" 27485175 "The expression signature of five miRNAs (miR-1296, miR-135b, miR-539, miR-572 and miR-185) was found to be prognostic [p = 1.28E-07, HR 8.4 (95 % CI: 3.81-18.52)] for DMFS." circulation_biomarker_prognosis_ns hsa-mir-539 "Carcinoma, Colon" 27485175 "The expression signature of five miRNAs (miR-1296, miR-135b, miR-539, miR-572 and miR-185) was found to be prognostic [p = 1.28E-07, HR 8.4 (95 % CI: 3.81-18.52)] for DMFS." circulation_biomarker_prognosis_ns hsa-mir-572 "Carcinoma, Colon" 27485175 "The expression signature of five miRNAs (miR-1296, miR-135b, miR-539, miR-572 and miR-185) was found to be prognostic [p = 1.28E-07, HR 8.4 (95 % CI: 3.81-18.52)] for DMFS." circulation_biomarker_prognosis_ns hsa-mir-592 "Carcinoma, Colon" 27485175 The expression of miR-592 was significantly associated with the MMR status (p.adjusted <0.01). circulation_biomarker_prognosis_ns hsa-mir-516a Breast Neoplasms 27528030 "Finally, we show that a combination of 2 miRNAs (miR-190b and miR-516a-5p) exhibiting altered expression in TamR cell lines were predictive of treatment outcome in a cohort of ER+ breast cancer patients receiving adjuvant tamoxifen mono-therapy." circulation_biomarker_prognosis_ns hsa-mir-34a "Carcinoma, Breast" 27561942 Human serum miR-34a as an indicator of exposure to ionizing radiation. circulation_biomarker_prognosis_ns hsa-mir-18a Retinoblastoma 27574784 "Downregulation of inhibitor of apoptosis proteins, tumor miRNA-18a, altered serum cytokines, and serum miRNA-18a levels were observed upon NCL-APT treatment" circulation_biomarker_prognosis_ns hsa-mir-21 "Carcinoma, Breast" 27696295 Serum microRNA-21 expression as a prognostic and therapeutic biomarker for breast cancer patients. circulation_biomarker_prognosis_ns hsa-mir-15b Multiple Sclerosis 27725128 "Effect of fingolimod treatment on circulating miR-15b, miR23a and miR-223 levels in patients with multiple sclerosis." circulation_biomarker_prognosis_ns hsa-mir-223 Multiple Sclerosis 27725128 "Effect of fingolimod treatment on circulating miR-15b, miR23a and miR-223 levels in patients with multiple sclerosis." circulation_biomarker_prognosis_ns hsa-mir-23a Multiple Sclerosis 27725128 "Effect of fingolimod treatment on circulating miR-15b, miR23a and miR-223 levels in patients with multiple sclerosis." circulation_biomarker_prognosis_ns hsa-mir-6826 "Carcinoma, Colon" 27878288 MicroRNA-6826 and -6875 in plasma are valuable non?invasive biomarkers that predict the efficacy of vaccine treatment against metastatic colorectal cancer. circulation_biomarker_prognosis_ns hsa-mir-6875 "Carcinoma, Colon" 27878288 MicroRNA-6826 and -6875 in plasma are valuable non?invasive biomarkers that predict the efficacy of vaccine treatment against metastatic colorectal cancer. circulation_biomarker_prognosis_ns hsa-let-7i "Carcinoma, Breast" 27959953 Identification of MicroRNAs as Breast Cancer Prognosis Markers through the Cancer Genome Atlas. circulation_biomarker_prognosis_ns hsa-mir-103a "Carcinoma, Breast" 27959953 Identification of MicroRNAs as Breast Cancer Prognosis Markers through the Cancer Genome Atlas. circulation_biomarker_prognosis_ns hsa-mir-140 "Carcinoma, Breast" 27959953 Identification of MicroRNAs as Breast Cancer Prognosis Markers through the Cancer Genome Atlas. circulation_biomarker_prognosis_ns hsa-mir-200c "Carcinoma, Breast" 27959953 Identification of MicroRNAs as Breast Cancer Prognosis Markers through the Cancer Genome Atlas. circulation_biomarker_prognosis_ns hsa-mir-21 "Carcinoma, Breast" 27959953 Identification of MicroRNAs as Breast Cancer Prognosis Markers through the Cancer Genome Atlas. circulation_biomarker_prognosis_ns hsa-mir-25 "Carcinoma, Breast" 27959953 Identification of MicroRNAs as Breast Cancer Prognosis Markers through the Cancer Genome Atlas. circulation_biomarker_prognosis_ns hsa-mir-30a "Carcinoma, Breast" 27959953 Identification of MicroRNAs as Breast Cancer Prognosis Markers through the Cancer Genome Atlas. circulation_biomarker_prognosis_ns hsa-mir-30c "Carcinoma, Breast" 27959953 Identification of MicroRNAs as Breast Cancer Prognosis Markers through the Cancer Genome Atlas. circulation_biomarker_prognosis_ns hsa-mir-320a "Carcinoma, Breast" 27959953 Identification of MicroRNAs as Breast Cancer Prognosis Markers through the Cancer Genome Atlas. circulation_biomarker_prognosis_ns hsa-mir-361 "Carcinoma, Breast" 27959953 Identification of MicroRNAs as Breast Cancer Prognosis Markers through the Cancer Genome Atlas. circulation_biomarker_prognosis_ns hsa-mir-374b "Carcinoma, Breast" 27959953 Identification of MicroRNAs as Breast Cancer Prognosis Markers through the Cancer Genome Atlas. circulation_biomarker_prognosis_ns hsa-mir-651 "Carcinoma, Breast" 27959953 Identification of MicroRNAs as Breast Cancer Prognosis Markers through the Cancer Genome Atlas. circulation_biomarker_prognosis_ns hsa-mir-101 Heart Transplant Rejection 28125729 Association of Serum MiR-142-3p and MiR-101-3p Levels with Acute Cellular Rejection after Heart Transplantation. circulation_biomarker_prognosis_ns hsa-mir-142 Heart Transplant Rejection 28125729 Association of Serum MiR-142-3p and MiR-101-3p Levels with Acute Cellular Rejection after Heart Transplantation. circulation_biomarker_prognosis_ns hsa-mir-33a "Carcinoma, Lung, Non-Small-Cell" 28141816 Association of microRNA-33a Molecular Signature with Non-Small Cell Lung Cancer Diagnosis and Prognosis after Chemotherapy. circulation_biomarker_prognosis_ns hsa-let-7b Multiple Myeloma 28213378 Prognostic role of circulating exosomal miRNAs in multiple myeloma. circulation_biomarker_prognosis_ns hsa-mir-18a Multiple Myeloma 28213378 Prognostic role of circulating exosomal miRNAs in multiple myeloma. circulation_biomarker_prognosis_ns hsa-mir-30d Heart Failure 28214846 Circulating miR-30d Predicts Survival in Patients with Acute Heart Failure. circulation_biomarker_prognosis_ns hsa-mir-106a Glioblastoma 28284220 Serum microRNA profiling in patients with glioblastoma: a survival analysis. circulation_biomarker_prognosis_ns hsa-mir-145 Glioblastoma 28284220 Serum microRNA profiling in patients with glioblastoma: a survival analysis. circulation_biomarker_prognosis_ns hsa-mir-182 Glioblastoma 28284220 Serum microRNA profiling in patients with glioblastoma: a survival analysis. circulation_biomarker_prognosis_ns hsa-mir-20a Glioblastoma 28284220 Serum microRNA profiling in patients with glioblastoma: a survival analysis. circulation_biomarker_prognosis_ns hsa-mir-222 Glioblastoma 28284220 Serum microRNA profiling in patients with glioblastoma: a survival analysis. circulation_biomarker_prognosis_ns hsa-mir-1274a "Carcinoma, Ovarian" 28293063 Evaluation of Prognostic and Predictive Significance of Circulating MicroRNAs in Ovarian Cancer Patients. circulation_biomarker_prognosis_ns hsa-mir-141 "Carcinoma, Ovarian" 28293063 Evaluation of Prognostic and Predictive Significance of Circulating MicroRNAs in Ovarian Cancer Patients. circulation_biomarker_prognosis_ns hsa-mir-200b "Carcinoma, Ovarian" 28293063 Evaluation of Prognostic and Predictive Significance of Circulating MicroRNAs in Ovarian Cancer Patients. circulation_biomarker_prognosis_ns hsa-mir-200c "Carcinoma, Ovarian" 28293063 Evaluation of Prognostic and Predictive Significance of Circulating MicroRNAs in Ovarian Cancer Patients. circulation_biomarker_prognosis_ns hsa-mir-200 Neoplasms [unspecific] 28321402 Prognostic Role of the MicroRNA-200 Family in Various Carcinomas: A Systematic Review and Meta-Analysis. circulation_biomarker_prognosis_ns hsa-mir-192 "Carcinoma, Periampullary" 28351309 Plasma microRNA192 in combination with serum CA19-9 as non-invasive prognostic biomarker in periampullary carcinoma. circulation_biomarker_prognosis_ns hsa-mir-122 "Lymphoma, Hodgkin" 28377796 Redox Regulating Enzymes and Connected MicroRNA Regulators Have Prognostic Value in Classical Hodgkin Lymphomas. circulation_biomarker_prognosis_ns hsa-mir-144 "Lymphoma, Hodgkin" 28377796 Redox Regulating Enzymes and Connected MicroRNA Regulators Have Prognostic Value in Classical Hodgkin Lymphomas. circulation_biomarker_prognosis_ns hsa-mir-212 "Lymphoma, Hodgkin" 28377796 Redox Regulating Enzymes and Connected MicroRNA Regulators Have Prognostic Value in Classical Hodgkin Lymphomas. circulation_biomarker_prognosis_ns hsa-mir-23b "Lymphoma, Hodgkin" 28377796 Redox Regulating Enzymes and Connected MicroRNA Regulators Have Prognostic Value in Classical Hodgkin Lymphomas. circulation_biomarker_prognosis_ns hsa-mir-510 "Lymphoma, Hodgkin" 28377796 Redox Regulating Enzymes and Connected MicroRNA Regulators Have Prognostic Value in Classical Hodgkin Lymphomas. circulation_biomarker_prognosis_ns hsa-mir-122 Chronic Hepatitis C 28401565 Serum and exosomal miR-122 and miR-199a as a biomarker to predict therapeutic efficacy of hepatitis C patients. circulation_biomarker_prognosis_ns hsa-mir-199a Chronic Hepatitis C 28401565 Serum and exosomal miR-122 and miR-199a as a biomarker to predict therapeutic efficacy of hepatitis C patients. circulation_biomarker_prognosis_ns hsa-mir-1 Atrial Fibrillation 28422282 "Analysis of Circulating miR-1, miR-23a, and miR-26a in Atrial Fibrillation Patients Undergoing Coronary Bypass Artery Grafting Surgery." circulation_biomarker_prognosis_ns hsa-mir-23a Atrial Fibrillation 28422282 "Analysis of Circulating miR-1, miR-23a, and miR-26a in Atrial Fibrillation Patients Undergoing Coronary Bypass Artery Grafting Surgery." circulation_biomarker_prognosis_ns hsa-mir-26a Atrial Fibrillation 28422282 "Analysis of Circulating miR-1, miR-23a, and miR-26a in Atrial Fibrillation Patients Undergoing Coronary Bypass Artery Grafting Surgery." circulation_biomarker_prognosis_ns hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 28599250 Evaluation of MiR-15a and MiR-16-1 as prognostic biomarkers in chronic lymphocytic leukemia. circulation_biomarker_prognosis_ns hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 28599250 Evaluation of MiR-15a and MiR-16-1 as prognostic biomarkers in chronic lymphocytic leukemia. circulation_biomarker_prognosis_ns hsa-mir-21 Preeclampsia 28694210 Circulating microRNA expression as predictor of preeclampsia and its severity. circulation_biomarker_prognosis_ns hsa-mir-125b "Carcinoma, Hepatocellular" 28814883 Serum exosomal miR-125b is a novel prognostic marker for hepatocellular carcinoma circulation_biomarker_prognosis_ns hsa-mir-34a "Fatty Liver, Non-Alcoholic" 28853202 Potentially pro-apoptotic miR-34a was reduced in the vesicle-free fraction in serum but not in liver after UDCA treatment circulation_biomarker_prognosis_ns hsa-mir-192 "Carcinoma, Urothelial" 28928837 "hsa-mir-7705, hsa-mir-192 and hsa-mir-518b can be applied as independent prognostic markers for bladder urothelial carcinoma" circulation_biomarker_prognosis_ns hsa-mir-518b "Carcinoma, Urothelial" 28928837 "hsa-mir-7705, hsa-mir-192 and hsa-mir-518b can be applied as independent prognostic markers for bladder urothelial carcinoma" circulation_biomarker_prognosis_ns hsa-mir-7705 "Carcinoma, Urothelial" 28928837 "hsa-mir-7705, hsa-mir-192 and hsa-mir-518b can be applied as independent prognostic markers for bladder urothelial carcinoma" circulation_biomarker_prognosis_ns hsa-mir-181a "Leukemia, Myeloid, Acute" 29166738 Expression characteristics and prognosis significance of miRNA-181a in acute myeloid leukemia with normal karyotype circulation_biomarker_prognosis_ns hsa-mir-122 "Carcinoma, Breast" 29243807 "some exosomal miRNAs including miR-126, miR-122, miR-92-1, miR-19a, and miR-29c together with circular miRNAs, such as miR-21-5p, miR-96-5p, and miR-125b-5p can provide a promising evaluation route in breast cancer prognosis" circulation_biomarker_prognosis_ns hsa-mir-125b "Carcinoma, Breast" 29243807 "some exosomal miRNAs including miR-126, miR-122, miR-92-1, miR-19a, and miR-29c together with circular miRNAs, such as miR-21-5p, miR-96-5p, and miR-125b-5p can provide a promising evaluation route in breast cancer prognosis" circulation_biomarker_prognosis_ns hsa-mir-126 "Carcinoma, Breast" 29243807 "some exosomal miRNAs including miR-126, miR-122, miR-92-1, miR-19a, and miR-29c together with circular miRNAs, such as miR-21-5p, miR-96-5p, and miR-125b-5p can provide a promising evaluation route in breast cancer prognosis" circulation_biomarker_prognosis_ns hsa-mir-19a "Carcinoma, Breast" 29243807 "some exosomal miRNAs including miR-126, miR-122, miR-92-1, miR-19a, and miR-29c together with circular miRNAs, such as miR-21-5p, miR-96-5p, and miR-125b-5p can provide a promising evaluation route in breast cancer prognosis" circulation_biomarker_prognosis_ns hsa-mir-21 "Carcinoma, Breast" 29243807 "some exosomal miRNAs including miR-126, miR-122, miR-92-1, miR-19a, and miR-29c together with circular miRNAs, such as miR-21-5p, miR-96-5p, and miR-125b-5p can provide a promising evaluation route in breast cancer prognosis" circulation_biomarker_prognosis_ns hsa-mir-29c "Carcinoma, Breast" 29243807 "some exosomal miRNAs including miR-126, miR-122, miR-92-1, miR-19a, and miR-29c together with circular miRNAs, such as miR-21-5p, miR-96-5p, and miR-125b-5p can provide a promising evaluation route in breast cancer prognosis" circulation_biomarker_prognosis_ns hsa-mir-92-1 "Carcinoma, Breast" 29243807 "some exosomal miRNAs including miR-126, miR-122, miR-92-1, miR-19a, and miR-29c together with circular miRNAs, such as miR-21-5p, miR-96-5p, and miR-125b-5p can provide a promising evaluation route in breast cancer prognosis" circulation_biomarker_prognosis_ns hsa-mir-96 "Carcinoma, Breast" 29243807 "some exosomal miRNAs including miR-126, miR-122, miR-92-1, miR-19a, and miR-29c together with circular miRNAs, such as miR-21-5p, miR-96-5p, and miR-125b-5p can provide a promising evaluation route in breast cancer prognosis" circulation_biomarker_prognosis_ns hsa-mir-148a "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" circulation_biomarker_prognosis_ns hsa-mir-192 "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" circulation_biomarker_prognosis_ns hsa-mir-21 "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" circulation_biomarker_prognosis_ns hsa-mir-224 "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" circulation_biomarker_prognosis_ns hsa-mir-16 "Carcinoma, Hepatocellular" 29333940 "Also, miR-16, miR-34a, and miR-221 serum levels would have a prognostic value" circulation_biomarker_prognosis_ns hsa-mir-221 "Carcinoma, Hepatocellular" 29333940 "Also, miR-16, miR-34a, and miR-221 serum levels would have a prognostic value" circulation_biomarker_prognosis_ns hsa-mir-34a "Carcinoma, Hepatocellular" 29333940 "Also, miR-16, miR-34a, and miR-221 serum levels would have a prognostic value" circulation_biomarker_prognosis_ns hsa-mir-155 Leukemia 29654787 miR-155 might be a promising prognostic biomarker for this patient population circulation_biomarker_prognosis_ns hsa-mir-126 Aplastic Anemia 29674506 "mir-126-5p, was negatively correlated with a response to therapy in aplastic anemia" circulation_biomarker_prognosis_ns hsa-mir-215 Lung Neoplasms 29683761 "we identified a signature of seven microRNAs (miR-215-5p, miR-411-3p, miR-493-5p, miR-494-3p, miR-495-3p, miR-548j-5p and miR-93-3p) significantly associated with overall survival" circulation_biomarker_prognosis_ns hsa-mir-411 Lung Neoplasms 29683761 "we identified a signature of seven microRNAs (miR-215-5p, miR-411-3p, miR-493-5p, miR-494-3p, miR-495-3p, miR-548j-5p and miR-93-3p) significantly associated with overall survival" circulation_biomarker_prognosis_ns hsa-mir-493 Lung Neoplasms 29683761 "we identified a signature of seven microRNAs (miR-215-5p, miR-411-3p, miR-493-5p, miR-494-3p, miR-495-3p, miR-548j-5p and miR-93-3p) significantly associated with overall survival" circulation_biomarker_prognosis_ns hsa-mir-494 Lung Neoplasms 29683761 "we identified a signature of seven microRNAs (miR-215-5p, miR-411-3p, miR-493-5p, miR-494-3p, miR-495-3p, miR-548j-5p and miR-93-3p) significantly associated with overall survival" circulation_biomarker_prognosis_ns hsa-mir-495 Lung Neoplasms 29683761 "we identified a signature of seven microRNAs (miR-215-5p, miR-411-3p, miR-493-5p, miR-494-3p, miR-495-3p, miR-548j-5p and miR-93-3p) significantly associated with overall survival" circulation_biomarker_prognosis_ns hsa-mir-548j Lung Neoplasms 29683761 "we identified a signature of seven microRNAs (miR-215-5p, miR-411-3p, miR-493-5p, miR-494-3p, miR-495-3p, miR-548j-5p and miR-93-3p) significantly associated with overall survival" circulation_biomarker_prognosis_ns hsa-mir-93 Lung Neoplasms 29683761 "we identified a signature of seven microRNAs (miR-215-5p, miR-411-3p, miR-493-5p, miR-494-3p, miR-495-3p, miR-548j-5p and miR-93-3p) significantly associated with overall survival" circulation_biomarker_prognosis_ns hsa-mir-3662 "Leukemia-Lymphoma, Adult T-Cell" 29684346 MicroRNA-3662 expression correlates with antiviral drug resistance in adult T-cell leukemia/lymphoma cells. circulation_biomarker_prognosis_ns hsa-mir-142 Coronary Artery Disease 29891858 Plasma miR-142 predicts major adverse cardiovascular events as an intermediate biomarker of dual antiplatelet therapy. circulation_biomarker_prognosis_ns hsa-mir-125b "Carcinoma, Pancreatic" 29913239 Plasma miR-125b-5p might act as an independent biomarker in predicting OS of PC patients circulation_biomarker_prognosis_ns hsa-mir-21 Liver Cirrhosis 29935272 MicroRNA profiles in serum samples from patients with stable cirrhosis and miRNA-21 as a predictor of transplant-free survival. circulation_biomarker_prognosis_ns hsa-mir-30a Myocardial Infarction 29959359 Circulating miR-30a-5p as a prognostic biomarker of left ventricular dysfunction after acute myocardial infarction. circulation_biomarker_prognosis_ns hsa-mir-122 "Carcinoma, Hepatocellular" 30127924 Serum exosomal microRNA-122 and microRNA-21 as predictive biomarkers in transarterial chemoembolization-treated hepatocellular carcinoma patients. circulation_biomarker_prognosis_ns hsa-mir-21 "Carcinoma, Hepatocellular" 30127924 Serum exosomal microRNA-122 and microRNA-21 as predictive biomarkers in transarterial chemoembolization-treated hepatocellular carcinoma patients. circulation_biomarker_prognosis_ns hsa-mir-141 Colon Neoplasms 30138915 Prognostic Impact of miR-200 Family Members in Plasma and Exosomes from Tumor-Draining versus Peripheral Veins of Colon Cancer Patients. circulation_biomarker_prognosis_ns hsa-mir-200a Colon Neoplasms 30138915 Prognostic Impact of miR-200 Family Members in Plasma and Exosomes from Tumor-Draining versus Peripheral Veins of Colon Cancer Patients. circulation_biomarker_prognosis_ns hsa-mir-200b Colon Neoplasms 30138915 Prognostic Impact of miR-200 Family Members in Plasma and Exosomes from Tumor-Draining versus Peripheral Veins of Colon Cancer Patients. circulation_biomarker_prognosis_ns hsa-mir-200c Colon Neoplasms 30138915 Prognostic Impact of miR-200 Family Members in Plasma and Exosomes from Tumor-Draining versus Peripheral Veins of Colon Cancer Patients. circulation_biomarker_prognosis_ns hsa-mir-429 Colon Neoplasms 30138915 Prognostic Impact of miR-200 Family Members in Plasma and Exosomes from Tumor-Draining versus Peripheral Veins of Colon Cancer Patients. circulation_biomarker_prognosis_ns hsa-mir-328 Colorectal Carcinoma 30166271 Serum-based microRNA signature predicts relapse and therapeutic outcome of adjuvant chemotherapy in colorectal cancer patients. circulation_biomarker_prognosis_ns hsa-mir-342 Colorectal Carcinoma 30166271 Serum-based microRNA signature predicts relapse and therapeutic outcome of adjuvant chemotherapy in colorectal cancer patients. circulation_biomarker_prognosis_ns hsa-mir-501 Colorectal Carcinoma 30166271 Serum-based microRNA signature predicts relapse and therapeutic outcome of adjuvant chemotherapy in colorectal cancer patients. circulation_biomarker_prognosis_ns hsa-mir-652 Colorectal Carcinoma 30166271 Serum-based microRNA signature predicts relapse and therapeutic outcome of adjuvant chemotherapy in colorectal cancer patients. circulation_biomarker_prognosis_ns hsa-mir-1202 Depression Disorder 30181751 "Serum-based microRNA biomarkers for major depression: MiR-16, miR-135a, and miR-1202." circulation_biomarker_prognosis_ns hsa-mir-135a Depression Disorder 30181751 "Serum-based microRNA biomarkers for major depression: MiR-16, miR-135a, and miR-1202." circulation_biomarker_prognosis_ns hsa-mir-16 Depression Disorder 30181751 "Serum-based microRNA biomarkers for major depression: MiR-16, miR-135a, and miR-1202." circulation_biomarker_prognosis_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 30190521 "combination of miR-1290, miR-196b and miR-135a in tumor tissue, and miR-21, miR-25, miR27b, and miR-326 in plasma were predictive for response to platinum-based chemotherapy in advanced NSCLC" circulation_biomarker_prognosis_ns hsa-mir-25 "Carcinoma, Lung, Non-Small-Cell" 30190521 "combination of miR-1290, miR-196b and miR-135a in tumor tissue, and miR-21, miR-25, miR27b, and miR-326 in plasma were predictive for response to platinum-based chemotherapy in advanced NSCLC" circulation_biomarker_prognosis_ns hsa-mir-27b "Carcinoma, Lung, Non-Small-Cell" 30190521 "combination of miR-1290, miR-196b and miR-135a in tumor tissue, and miR-21, miR-25, miR27b, and miR-326 in plasma were predictive for response to platinum-based chemotherapy in advanced NSCLC" circulation_biomarker_prognosis_ns hsa-mir-326 "Carcinoma, Lung, Non-Small-Cell" 30190521 "combination of miR-1290, miR-196b and miR-135a in tumor tissue, and miR-21, miR-25, miR27b, and miR-326 in plasma were predictive for response to platinum-based chemotherapy in advanced NSCLC" circulation_biomarker_prognosis_ns hsa-mir-125a "Leukemia, Lymphocytic, Chronic, B-Cell" 30242085 MiR-125a and MiR-34a expression predicts Richter syndrome in chronic lymphocytic leukemia patients. circulation_biomarker_prognosis_ns hsa-mir-34a "Leukemia, Lymphocytic, Chronic, B-Cell" 30242085 MiR-125a and MiR-34a expression predicts Richter syndrome in chronic lymphocytic leukemia patients. circulation_biomarker_prognosis_ns hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 30336280 "Prognostic significance of circulating microRNA-21 expression in esophageal, pancreatic and colorectal cancers; a systematic review and meta-analysis." circulation_biomarker_prognosis_ns hsa-mir-21 Colorectal Carcinoma 30336280 "Prognostic significance of circulating microRNA-21 expression in esophageal, pancreatic and colorectal cancers; a systematic review and meta-analysis." circulation_biomarker_prognosis_ns hsa-mir-21 "Squamous Cell Carcinoma, Esophageal" 30336280 "Prognostic significance of circulating microRNA-21 expression in esophageal, pancreatic and colorectal cancers; a systematic review and meta-analysis." circulation_biomarker_prognosis_ns hsa-mir-155 "Leukemia, Lymphoblastic, Acute" 30362157 miRNA-155 and miRNA-181a as prognostic biomarkers for pediatric acute lymphoblastic leukemia. circulation_biomarker_prognosis_ns hsa-mir-181a "Leukemia, Lymphoblastic, Acute" 30362157 miRNA-155 and miRNA-181a as prognostic biomarkers for pediatric acute lymphoblastic leukemia. circulation_biomarker_prognosis_up hsa-mir-29b Encephalitis 30196835 Increased serum microRNA-29b expression and bad recovery in Japanese encephalitis virus infected patients; A new component to improve the disease recovery. circulation_biomarker_prognosis_up hsa-mir-155 Lung Neoplasms 17028302 A high expression of miR-155 has been suggested to be significantly associated with unfavorable prognosis in lung adenocarcinoma patients. circulation_biomarker_prognosis_up hsa-mir-155 Lung Neoplasms 17028596 "High mir-155 associated with poor prognosis in lung cancer (Yanaihara et al., 2006)." circulation_biomarker_prognosis_up hsa-mir-125b-1 Rectal Neoplasms 18695884 miR-125b: frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer circulation_biomarker_prognosis_up hsa-mir-125b-2 Rectal Neoplasms 18695884 miR-125b: frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer circulation_biomarker_prognosis_up hsa-mir-137 Rectal Neoplasms 18695884 miR-137: frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer circulation_biomarker_prognosis_up hsa-mir-21 Breast Neoplasms 18812439 "miR-21: miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis" circulation_biomarker_prognosis_up hsa-mir-211 "Carcinoma, Oral" 18946016 miR-211: Association between high miR-211 microRNA expression and the poor prognosis circulation_biomarker_prognosis_up hsa-mir-155 Waldenstrom Macroglobulinemia 19074725 miR-155: increased expression circulation_biomarker_prognosis_up hsa-mir-184 Waldenstrom Macroglobulinemia 19074725 miR-184: increased expression circulation_biomarker_prognosis_up hsa-mir-206 Waldenstrom Macroglobulinemia 19074725 miR-206: increased expression circulation_biomarker_prognosis_up hsa-mir-363 Waldenstrom Macroglobulinemia 19074725 miR-363*: increased expression circulation_biomarker_prognosis_up hsa-mir-494 Waldenstrom Macroglobulinemia 19074725 miR-494: increased expression circulation_biomarker_prognosis_up hsa-mir-542 Waldenstrom Macroglobulinemia 19074725 miR-542-3p: increased expression circulation_biomarker_prognosis_up hsa-mir-21 Pancreatic Neoplasms 21139804 upregulated and correlated with worse survival circulation_biomarker_prognosis_up hsa-mir-221 "Carcinoma, Hepatocellular" 21295551 "Serum miR-221, upregulated in HCC, can provide predictive significance for prognosis of HCC patients." circulation_biomarker_prognosis_up hsa-mir-141 Colorectal Carcinoma 21445232 High levels of plasma miR-141 predicted poor survival in both cohorts and that miR-141 was an independent prognostic factor for advanced colon cancer. circulation_biomarker_prognosis_up hsa-mir-200c Lung Neoplasms 21516486 High expression of serum miR-21 and tumor miR-200c associated with poor prognosis in patients with lung cancer circulation_biomarker_prognosis_up hsa-mir-21 Lung Neoplasms 21516486 High expression of serum miR-21 and tumor miR-200c associated with poor prognosis in patients with lung cancer circulation_biomarker_prognosis_up hsa-mir-663a "Leukemia, Myeloid, Acute" 21518431 Retinoic acid induces HL-60 cell differentiation via the upregulation of miR-663 circulation_biomarker_prognosis_up hsa-mir-183 Lung Neoplasms 21920043 Expression levels of members of the miR-183 family in lung cancer tumor and sera were higher than that of their normal counterparts. The miR-96 expression in tumors was positively associated with its expression in sera. Log-rank and Cox regression analyses demonstrated that high expression of tumor and serum miRNAs of the miR-183 family were associated with overall poor survival in patients with lung cancer. circulation_biomarker_prognosis_up hsa-mir-96 Lung Neoplasms 21920043 Expression levels of members of the miR-183 family in lung cancer tumor and sera were higher than that of their normal counterparts. The miR-96 expression in tumors was positively associated with its expression in sera. Log-rank and Cox regression analyses demonstrated that high expression of tumor and serum miRNAs of the miR-183 family were associated with overall poor survival in patients with lung cancer. circulation_biomarker_prognosis_up hsa-mir-21 Lymphoma 22541087 The expression of miR-21 in plasma of lymphoma patient group significantly correlated with their serum LDH level. The expressions of miR-21 and miR-210 in plasma of previously untreated lymphoma patient group were higher than those of the patients treated for 6 or more courses circulation_biomarker_prognosis_up hsa-mir-210 Lymphoma 22541087 The expression of miR-21 in plasma of lymphoma patient group significantly correlated with their serum LDH level. The expressions of miR-21 and miR-210 in plasma of previously untreated lymphoma patient group were higher than those of the patients treated for 6 or more courses circulation_biomarker_prognosis_up hsa-let-7d Glioblastoma 22722712 "miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract)." circulation_biomarker_prognosis_up hsa-mir-155 Acute Myocardial Infarction 22995291 "Real-time RT-PCR confirmed that the serum levels of miR-155 and miR-380* were approximately 4- and 3-fold higher, respectively, in patients who experienced cardiac death within 1 year after discharge." circulation_biomarker_prognosis_up hsa-mir-380 Acute Myocardial Infarction 22995291 "Real-time RT-PCR confirmed that the serum levels of miR-155 and miR-380* were approximately 4- and 3-fold higher, respectively, in patients who experienced cardiac death within 1 year after discharge." circulation_biomarker_prognosis_up hsa-mir-100 "Leukemia, Myeloid, Acute" 23055746 Upregulation of microRNA-100 predicts poor prognosis in patients with pediatric acute myeloid leukemia circulation_biomarker_prognosis_up hsa-mir-1 Heart Failure 23079087 Elevated plasma microRNA-1 predicts heart failure after acute myocardial infarction. circulation_biomarker_prognosis_up hsa-mir-17 "Carcinoma, Hepatocellular" 23108086 High expression of serum miR-17-5p associated with poor prognosis in patients with hepatocellular carcinoma circulation_biomarker_prognosis_up hsa-mir-200c "Lymphoma, Large B-Cell, Diffuse" 23232598 High expression of microRNA-200c predicts poor clinical outcome in diffuse large B-cell lymphoma circulation_biomarker_prognosis_up hsa-mir-221 "Leukemia, Lymphoblastic, Acute" 23566596 Increased expression of miR-221 is associated with shorter overall survival in T-cell acute lymphoid leukemia circulation_biomarker_prognosis_up hsa-mir-146b Prostate Neoplasms 23846169 Multivariate analysis revealed that miR-146b-3p possessed prognostic information beyond standard clinicopathological parameters. circulation_biomarker_prognosis_up hsa-mir-194 Prostate Neoplasms 23846169 "Analysis of tissue cohorts revealed that miR-194 was robustly expressed in the prostate, elevated in metastases, and its expression in primary tumours was associated with a poor prognosis." circulation_biomarker_prognosis_up hsa-mir-375 "Leukemia, Myeloid, Acute" 23864342 Upregulation of microRNA-375 is associated with poor prognosis in pediatric acute myeloid leukemia. circulation_biomarker_prognosis_up hsa-mir-27a Neoplasms [unspecific] 24122958 miRNA27a is a biomarker for predicting chemosensitivity and prognosis in metastatic or recurrent gastric cancer. circulation_biomarker_prognosis_up hsa-mir-221 "Carcinoma, Renal Cell" 24379138 Higher circulating expression levels of miR-221 associated with poor overall survival in renal cell carcinoma patients. circulation_biomarker_prognosis_up hsa-mir-10b Breast Neoplasms 24416156 "High levels of miR-21 and miR-10b were present in the serum of patients with non-metastatic and metastatic HER2(+) breast cancer, respectively. High levels of serum miR-19a may represent a biomarker for IBC that is predictive for favorable clinical outcome in patients with metastatic HER2(+) IBC." circulation_biomarker_prognosis_up hsa-mir-19a Breast Neoplasms 24416156 "High levels of miR-21 and miR-10b were present in the serum of patients with non-metastatic and metastatic HER2(+) breast cancer, respectively. High levels of serum miR-19a may represent a biomarker for IBC that is predictive for favorable clinical outcome in patients with metastatic HER2(+) IBC." circulation_biomarker_prognosis_up hsa-mir-21 Breast Neoplasms 24416156 "High levels of miR-21 and miR-10b were present in the serum of patients with non-metastatic and metastatic HER2(+) breast cancer, respectively. High levels of serum miR-19a may represent a biomarker for IBC that is predictive for favorable clinical outcome in patients with metastatic HER2(+) IBC." circulation_biomarker_prognosis_up hsa-mir-210 Aortic Stenosis 24626394 Circulating miR-210 levels are increased in patients with AS and provide independent prognostic information to established risk indices.Analytical characteristics were also excellent supporting the potential of micro-RNAs as novel CV biomarkers. circulation_biomarker_prognosis_up hsa-mir-221 Prostate Neoplasms 24760272 Influence of peripheral whole-blood microRNA-7 and microRNA-221 high expression levels on the acquisition of castration-resistant prostate cancer: evidences from in vitro and in vivo studies. circulation_biomarker_prognosis_up hsa-mir-7 Prostate Neoplasms 24760272 Influence of peripheral whole-blood microRNA-7 and microRNA-221 high expression levels on the acquisition of castration-resistant prostate cancer: evidences from in vitro and in vivo studies. circulation_biomarker_prognosis_up hsa-mir-200c Neoplasms [unspecific] 24870778 Low expression of microRNA 200c in tumor tissue and high expression of microRNA 200c in serum are associated with worse survival in solid tumors. Further study is needed to elucidate this contradiction. circulation_biomarker_prognosis_up hsa-mir-15b Melanoma 25155861 Serum miR-15b levels significantly increased over time in recurrent patients circulation_biomarker_prognosis_up hsa-mir-21 Breast Neoplasms 25277099 "Women with metastatic breast cancer, especially CSII, presented up-regulated levels of miR-183, miR-494 and miR-21, which were associated with a poor prognosis." circulation_biomarker_prognosis_up hsa-mir-221 "Carcinoma, Lung, Non-Small-Cell" 25466375 High serum miR-155 and miR-221 during the first 2 weeks of CRT were associated with the development of severe RIET circulation_biomarker_prognosis_up hsa-mir-155 Breast Neoplasms 25503185 a possible involvement of miR-155 in surgery-induced angiogenesis and potential prognostic significance of high postoperative levels of circulating miR-195 in patients with breast cancer. circulation_biomarker_prognosis_up hsa-mir-195 Breast Neoplasms 25503185 a possible involvement of miR-155 in surgery-induced angiogenesis and potential prognostic significance of high postoperative levels of circulating miR-195 in patients with breast cancer. circulation_biomarker_prognosis_up hsa-mir-21 Breast Neoplasms 25503185 a possible involvement of miR-155 in surgery-induced angiogenesis and potential prognostic significance of high postoperative levels of circulating miR-195 in patients with breast cancer. circulation_biomarker_prognosis_up hsa-mir-183 Colorectal Carcinoma 25629978 the elevated miR-183 in the plasma could be a promising biomarker for predicting the risk of tumor recurrence and poor survival in CRC patients. circulation_biomarker_prognosis_up hsa-mir-122 "Carcinoma, Hepatocellular" 25636448 "high serum miR-122 level is independently associated with higher overall survival rate in hepatocellular carcinoma patients, and it is a good biomarker of better prognosis in patients with hepatocellular carcinoma." circulation_biomarker_prognosis_up hsa-mir-24 "Leukemia, Acute" 25672522 High miR-24 expression is associated with risk of relapse and poor survival in acute leukemia. circulation_biomarker_prognosis_up hsa-mir-18a "Squamous Cell Carcinoma, Head and Neck" 25677760 "significant elevated expressions of miR-21, miR-18a, miR-134a, miR-210, miR-181a, miR-19a, and miR-155 were associated with poor survival in human HNSCC." circulation_biomarker_prognosis_up hsa-mir-18b Lymphoma 25736311 miR-18b overexpression identifies mantle cell lymphoma patients with poor outcome and improves the MIPI-B prognosticator. circulation_biomarker_prognosis_up hsa-mir-183 Tuberculosis 25755759 High serum miR-183 level is associated with the bioactivity of macrophage derived from tuberculosis patients. circulation_biomarker_prognosis_up hsa-mir-126 "Leukemia, Myeloid, Acute" 25759982 "The results of the present study demonstrated that higher expression levels of miR-126-5p/3p in patients with AML resulted in a poorer prognosis. Furthermore, miR-126-5p elevated the phosphorylation of Akt." circulation_biomarker_prognosis_up hsa-mir-21 Brain Neoplasms 25790954 "microRNA-21 is associated with the prognosis of patients with brain tumors, and high expression of microRNA-21 can predict poor prognosis in patients with brain tumors." circulation_biomarker_prognosis_up hsa-mir-206 Myotonic Muscular Dystrophy 25915631 "Specifically, miR-1, miR-133a, miR133b and miR-206 serum levels were found elevated in DM1 patients with progressive muscle wasting compared to disease stable DM1 patients." circulation_biomarker_prognosis_up hsa-mir-155 Bladder Neoplasms 25918190 We found that elevated expression of miR-155 is correlated with a poor outcome for patients with bladder cancer; this suggests that miR-155 is a potential biomarker for bladder cancer prognosis. circulation_biomarker_prognosis_up hsa-mir-17 Colorectal Carcinoma 26057451 Abundant expression of exosomal miR-19a in serum was identified as a prognostic biomarker for recurrence in CRC patients. circulation_biomarker_prognosis_up hsa-mir-18 Colorectal Carcinoma 26057451 Abundant expression of exosomal miR-19a in serum was identified as a prognostic biomarker for recurrence in CRC patients. circulation_biomarker_prognosis_up hsa-mir-19a Colorectal Carcinoma 26057451 Abundant expression of exosomal miR-19a in serum was identified as a prognostic biomarker for recurrence in CRC patients. circulation_biomarker_prognosis_up hsa-mir-19b-1 Colorectal Carcinoma 26057451 Abundant expression of exosomal miR-19a in serum was identified as a prognostic biomarker for recurrence in CRC patients. circulation_biomarker_prognosis_up hsa-mir-20a Colorectal Carcinoma 26057451 Abundant expression of exosomal miR-19a in serum was identified as a prognostic biomarker for recurrence in CRC patients. circulation_biomarker_prognosis_up hsa-mir-92-1 Colorectal Carcinoma 26057451 Abundant expression of exosomal miR-19a in serum was identified as a prognostic biomarker for recurrence in CRC patients. circulation_biomarker_prognosis_up hsa-mir-183 Kidney Neoplasms 26091793 High serum miR-183 level is associated with poor responsiveness of renal cancer to natural killer cells. circulation_biomarker_prognosis_up hsa-mir-551b "Leukemia, Myeloid, Acute" 26108690 MicroRNA-551b is highly expressed in hematopoietic stem cells and a biomarker for relapse and poor prognosis in acute myeloid leukemia. circulation_biomarker_prognosis_up hsa-mir-483 "Adenocarcinoma, Pancreatic Ductal" 26124009 Elevated miR-483-3p expression is an early event and indicates poor prognosis in pancreatic ductal adenocarcinoma. circulation_biomarker_prognosis_up hsa-mir-122 "Carcinoma, Hepatocellular" 26129878 High plasma microRNA-122 expression was associated with poor OS in patients with HBV-related hepatocellular carcinoma who underwent RFA. circulation_biomarker_prognosis_up hsa-mir-21 Prostate Neoplasms 26247873 "Our study demonstrates that high miR-21 expression levels in PBMCs were correlated with the presence, recurrence, and metastasis of PCa and that this may be a useful biomarker for screening PCa and monitoring the risk of Pca recurrence and metastasis." circulation_biomarker_prognosis_up hsa-mir-141 Malignant Neoplasms [unspecific] 26556949 "Our findings indicated that, compared to their tissue counterparts, the expression level of miR-200c and miR-141 in peripheral blood may be more effective for monitoring cancer prognosis. High miR-141 expression was better at predicting tumor progression than survival for malignant tumors." circulation_biomarker_prognosis_up hsa-mir-203 Colorectal Carcinoma 26701878 "Serum miR-203 levels were significantly upregulated in a stage-dependent manner, and high miR-203 expression was associated with poor survival in patients with CRC in both patient cohorts." circulation_biomarker_prognosis_up hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 26705427 Upregulation of these microRNAs was associated with a significantly shorter overall survival and recurrence-free survival circulation_biomarker_prognosis_up hsa-mir-210 "Adenocarcinoma, Pancreatic Ductal" 26705427 Upregulation of these microRNAs was associated with a significantly shorter overall survival and recurrence-free survival circulation_biomarker_prognosis_up hsa-mir-34a "Lymphoma, B-Cell" 26854484 High miR-34a expression improves response to doxorubicin in diffuse large B-cell lymphoma. circulation_biomarker_prognosis_up hsa-mir-125b "Lymphoma, Large B-Cell" 26870228 high miR-125b indicated poor prognosis circulation_biomarker_prognosis_up hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 26969625 Our meta-analysis indicated that elevated miR-21 expression level can predict poor prognosis in patients with PDAC. circulation_biomarker_prognosis_up hsa-mir-17 "Lymphoma, Burkitt" 27044389 miR-17-92 cluster components analysis in Burkitt lymphoma: overexpression of miR-17 is associated with poor prognosis. circulation_biomarker_prognosis_up hsa-mir-20a "Lymphoma, Burkitt" 27044389 We found that upregulated expression of miR-17 and miR-20a correlates with lack of pro-apoptotic Bim expression. circulation_biomarker_prognosis_up hsa-mir-125b Rectum Adenocarcinoma 27081702 High miR-125b expression in tissue and serum were associated with a poor treatment response in LARC patients circulation_biomarker_prognosis_up hsa-mir-21 Cervical Neoplasms 27101583 Increased circulating miR-21 expression in serum is associated with lymph node metastasis in patients with cervical cancer. circulation_biomarker_prognosis_up hsa-mir-29c Diabetic Nephropathy 27279796 "miR-21, miR-29a/b/c and miR-192 could reflect DN pathogenesis" circulation_biomarker_prognosis_up hsa-mir-21 "Carcinoma, Urothelial" 27383043 miR-21 may be a prognostic marker for cancer progression. circulation_biomarker_prognosis_up hsa-mir-1260b Colorectal Carcinoma 27399918 The high expression level of miR-1260b is an independent prognostic biomarker that indicates a worse prognosis for patients with CRC. circulation_biomarker_prognosis_up hsa-mir-10b Pancreatic Adenocarcinoma 27456015 We conclude that elevated miRNA-10b levels in station 8 lymph nodes could be utilized to assess risk for early disease progression in patients with periampullary tumors. circulation_biomarker_prognosis_up hsa-mir-522 "Carcinoma, Hepatocellular" 27466991 Upregulation of miR-522 is associated with poor outcome of hepatocellular carcinoma. circulation_biomarker_prognosis_up hsa-mir-18b "Carcinoma, Colon" 27485175 "The expression of several novel miRNAs were found to be tumour specific, e.g. miR-888, miR-523, miR-18b, miR-302a, miR-423-5p, miR-582-3p (p < 0.05)." circulation_biomarker_prognosis_up hsa-mir-302a "Carcinoma, Colon" 27485175 "The expression of several novel miRNAs were found to be tumour specific, e.g. miR-888, miR-523, miR-18b, miR-302a, miR-423-5p, miR-582-3p (p < 0.05)." circulation_biomarker_prognosis_up hsa-mir-423 "Carcinoma, Colon" 27485175 "The expression of several novel miRNAs were found to be tumour specific, e.g. miR-888, miR-523, miR-18b, miR-302a, miR-423-5p, miR-582-3p (p < 0.05)." circulation_biomarker_prognosis_up hsa-mir-523 "Carcinoma, Colon" 27485175 "The expression of several novel miRNAs were found to be tumour specific, e.g. miR-888, miR-523, miR-18b, miR-302a, miR-423-5p, miR-582-3p (p < 0.05)." circulation_biomarker_prognosis_up hsa-mir-582 "Carcinoma, Colon" 27485175 "The expression of several novel miRNAs were found to be tumour specific, e.g. miR-888, miR-523, miR-18b, miR-302a, miR-423-5p, miR-582-3p (p < 0.05)." circulation_biomarker_prognosis_up hsa-mir-888 "Carcinoma, Colon" 27485175 "The expression of several novel miRNAs were found to be tumour specific, e.g. miR-888, miR-523, miR-18b, miR-302a, miR-423-5p, miR-582-3p (p < 0.05)." circulation_biomarker_prognosis_up hsa-mir-101 "Carcinoma, Hepatocellular" 27498785 "High miR-101 expression, vascular invasion, tumor size â‰? cm and late pathological stage were the risk factors of recurrence-free survival rate." circulation_biomarker_prognosis_up hsa-mir-155 "Leukemia, Myeloid, Acute" 27511899 High miR-155 expression is an adverse prognostic factor in pediatric NK-AML patients. circulation_biomarker_prognosis_up hsa-mir-133a Hypertension 27514547 The hypertensive ocean seamen had significantly higher expression levels of microRNA21 and MicroRNA133a than the healthy ocean seamen. circulation_biomarker_prognosis_up hsa-mir-21 Hypertension 27514547 The hypertensive ocean seamen had significantly higher expression levels of microRNA21 and MicroRNA133a than the healthy ocean seamen. circulation_biomarker_prognosis_up hsa-mir-21 Glioblastoma 27531352 Further subgroup analysis indicated that increased expression of miRNA-21 was also associated with OS in GBM patients. circulation_biomarker_prognosis_up hsa-mir-21 Glioma 27531352 Our analysis revealed that the high expression of miRNA-21 is associated with the worse OS in gliomas. circulation_biomarker_prognosis_up hsa-mir-155 "Leukemia, Myeloid, Acute" 27531760 The high expression of miR-155 is an poor prognostic factor for patients with AML. circulation_biomarker_prognosis_up hsa-mir-181c Cholangiocarcinoma 27533020 Down-regulation of NDRG2 and overexpression of miR-181c or LIF are significantly associated with a poorer overall survival (OS) in CCA patients. circulation_biomarker_prognosis_up hsa-mir-126 Diabetic Foot 27623390 Increasing the miR-126 expression in the peripheral blood of patients with diabetic foot ulcers treated with maggot debridement therapy. circulation_biomarker_prognosis_up hsa-mir-21 B-cell Childhood Acute Lymphoblastic Leukemia 28253825 Upregulation of microRNA-21 is a poor prognostic marker in patients with childhood B cell acute lymphoblastic leukemia. circulation_biomarker_prognosis_up hsa-mir-203 Breast Neoplasms 28351024 the upregulation of circulating miR-203 in blood was associated with poor prognosis in colorectal cancer and breast cancer circulation_biomarker_prognosis_up hsa-mir-203 Colorectal Carcinoma 28351024 the upregulation of circulating miR-203 in blood was associated with poor prognosis in colorectal cancer and breast cancer circulation_biomarker_prognosis_up hsa-mir-146b "Leukemia, Myeloid, Acute" 28473658 high expression of hsa-miR-146b was independent poor prognostic factor circulation_biomarker_prognosis_up hsa-mir-181c "Leukemia, Myeloid, Acute" 28473658 high expression of hsa-miR-181c and hsa-miR-4786 appeared to be favorable factors circulation_biomarker_prognosis_up hsa-mir-206 Rhabdomyosarcoma 28834127 "Serum microRNA-206 levels were elevated and remained high after three cycles of vincristine, dactinomycin, and cyclophosphamide (VAC)" circulation_biomarker_prognosis_up hsa-mir-146b Breast Neoplasms 29189128 "up-regulation of miR181b, miR-34a, miR-16, miR-15a and miR-146b-5p, and down-regulation of miR-19a and miR-19b have been shown following the treatment of several breast cancer cell lines with curcumin" circulation_biomarker_prognosis_up hsa-mir-15a Breast Neoplasms 29189128 "up-regulation of miR181b, miR-34a, miR-16, miR-15a and miR-146b-5p, and down-regulation of miR-19a and miR-19b have been shown following the treatment of several breast cancer cell lines with curcumin" circulation_biomarker_prognosis_up hsa-mir-16 Breast Neoplasms 29189128 "up-regulation of miR181b, miR-34a, miR-16, miR-15a and miR-146b-5p, and down-regulation of miR-19a and miR-19b have been shown following the treatment of several breast cancer cell lines with curcumin" circulation_biomarker_prognosis_up hsa-mir-181b Breast Neoplasms 29189128 "up-regulation of miR181b, miR-34a, miR-16, miR-15a and miR-146b-5p, and down-regulation of miR-19a and miR-19b have been shown following the treatment of several breast cancer cell lines with curcumin" circulation_biomarker_prognosis_up hsa-mir-34a Breast Neoplasms 29189128 "up-regulation of miR181b, miR-34a, miR-16, miR-15a and miR-146b-5p, and down-regulation of miR-19a and miR-19b have been shown following the treatment of several breast cancer cell lines with curcumin" circulation_biomarker_prognosis_up hsa-mir-155 Stevens-Johnson Syndrome 29644860 "MiR-155 up-regulation wasdetected in PBMCs from all hypersensitive patients 24 h after drug treatment, while miR-18a and miR-21 expression was up-regulated after 48 h" circulation_biomarker_prognosis_up hsa-mir-133b Atrial Fibrillation 29676832 "The miRNAs had different expression profiles dependent on the AF condition, with higher expression in the acute new-onset AF than well-controlled AF" circulation_biomarker_prognosis_up hsa-mir-328 Atrial Fibrillation 29676832 "The miRNAs had different expression profiles dependent on the AF condition, with higher expression in the acute new-onset AF than well-controlled AF" circulation_biomarker_prognosis_up hsa-mir-499 Atrial Fibrillation 29676832 "The miRNAs had different expression profiles dependent on the AF condition, with higher expression in the acute new-onset AF than well-controlled AF" circulation_biomarker_prognosis_up hsa-mir-103a "Diabetes Mellitus, Type 1" 29679626 "miR-103a-3p, miR-155-5p, miR-200a-3p, and miR-210-3p were confirmed as being upregulated in recently-diagnosed T1DM patients compared with controls or patients with ¡Ý5?years of diagnosis" circulation_biomarker_prognosis_up hsa-mir-155 "Diabetes Mellitus, Type 1" 29679626 "miR-103a-3p, miR-155-5p, miR-200a-3p, and miR-210-3p were confirmed as being upregulated in recently-diagnosed T1DM patients compared with controls or patients with ¡Ý5?years of diagnosis" circulation_biomarker_prognosis_up hsa-mir-200a "Diabetes Mellitus, Type 1" 29679626 "miR-103a-3p, miR-155-5p, miR-200a-3p, and miR-210-3p were confirmed as being upregulated in recently-diagnosed T1DM patients compared with controls or patients with ¡Ý5?years of diagnosis" circulation_biomarker_prognosis_up hsa-mir-210 "Diabetes Mellitus, Type 1" 29679626 "miR-103a-3p, miR-155-5p, miR-200a-3p, and miR-210-3p were confirmed as being upregulated in recently-diagnosed T1DM patients compared with controls or patients with ¡Ý5?years of diagnosis" circulation_biomarker_prognosis_up hsa-mir-502 Aneurysmal Subarachnoid Hemorrhage 29689401 Persistent High Levels of miR-502-5p Are Associated with Poor Neurologic Outcome in Patients with Aneurysmal Subarachnoid Hemorrhage. circulation_biomarker_prognosis_up hsa-mir-20a "Carcinoma, Breast" 30099860 "baseline miR-222 overexpression, C2 miR-20a up-regulation and C2 miR-451 down-regulation were predictive markers of response to NCT in HR+/HER2- breast cancer" circulation_biomarker_prognosis_up hsa-mir-222 "Carcinoma, Breast" 30099860 "baseline miR-222 overexpression, C2 miR-20a up-regulation and C2 miR-451 down-regulation were predictive markers of response to NCT in HR+/HER2- breast cancer" circulation_biomarker_prognosis_up hsa-mir-126 Osteoarthritis 30105874 "Circulating miRNA expression profiles act as important roles in knee OA patients underwent celecoxib treatment, and miR-126-5p, miR-320a as well as miR-146a-5p might correlate with treatment response to celecoxib" circulation_biomarker_prognosis_up hsa-mir-320a Osteoarthritis 30105874 "Circulating miRNA expression profiles act as important roles in knee OA patients underwent celecoxib treatment, and miR-126-5p, miR-320a as well as miR-146a-5p might correlate with treatment response to celecoxib" circulation_biomarker_prognosis_up hsa-mir-509 "Leukemia, Myeloid, Acute" 30242879 "the high expression of hsa-miR-509 and hsa-miR-542 were independent poor prognostic factors, whereas that of hsa-miR-146a and hsa-miR-3667 had a trend to be favorable factors" circulation_biomarker_prognosis_up hsa-mir-542 "Leukemia, Myeloid, Acute" 30242879 "the high expression of hsa-miR-509 and hsa-miR-542 were independent poor prognostic factors, whereas that of hsa-miR-146a and hsa-miR-3667 had a trend to be favorable factors" circulation_biomarker_prognosis_up hsa-mir-1273g Ovarian Neoplasms 30264202 hsa-miR-1273g-3p may be used as a prognostic marker for recurrent EOC after chemotherapy circulation_biomarker_prognosis_up hsa-mir-183 Major Depressive Disorder 30269040 Antidepressant treatment increased serum miR-183 and miR-212 levels in patients with major depressive disorder. circulation_biomarker_prognosis_up hsa-mir-212 Major Depressive Disorder 30269040 Antidepressant treatment increased serum miR-183 and miR-212 levels in patients with major depressive disorder. circulation_biomarker_prognosis_up hsa-mir-1246 Plasmodium Falciparum Malaria 30352683 "we identified five enriched upregulated miRNA sets (miR-3135b, miR-6780b-5p, miR-1246, miR-6126, and miR-3613-5p) as potential blood biomarkers of immunopathological status and prediction of early host responses, disease prognosis, and severe outcomes in AIFM" circulation_biomarker_prognosis_up hsa-mir-3135b Plasmodium Falciparum Malaria 30352683 "we identified five enriched upregulated miRNA sets (miR-3135b, miR-6780b-5p, miR-1246, miR-6126, and miR-3613-5p) as potential blood biomarkers of immunopathological status and prediction of early host responses, disease prognosis, and severe outcomes in AIFM" circulation_biomarker_prognosis_up hsa-mir-3613 Plasmodium Falciparum Malaria 30352683 "we identified five enriched upregulated miRNA sets (miR-3135b, miR-6780b-5p, miR-1246, miR-6126, and miR-3613-5p) as potential blood biomarkers of immunopathological status and prediction of early host responses, disease prognosis, and severe outcomes in AIFM" circulation_biomarker_prognosis_up hsa-mir-6126 Plasmodium Falciparum Malaria 30352683 "we identified five enriched upregulated miRNA sets (miR-3135b, miR-6780b-5p, miR-1246, miR-6126, and miR-3613-5p) as potential blood biomarkers of immunopathological status and prediction of early host responses, disease prognosis, and severe outcomes in AIFM" circulation_biomarker_prognosis_up hsa-mir-6780b Plasmodium Falciparum Malaria 30352683 "we identified five enriched upregulated miRNA sets (miR-3135b, miR-6780b-5p, miR-1246, miR-6126, and miR-3613-5p) as potential blood biomarkers of immunopathological status and prediction of early host responses, disease prognosis, and severe outcomes in AIFM" circulation_biomarker_prognosis_up hsa-mir-200c Colorectal Carcinoma 30381824 Detection of Circulating MicroRNAs with Ago2 Complexes to Monitor the Tumor Dynamics of Colorectal Cancer Patients during Chemotherapy. epigenetics hsa-mir-195 "Carcinoma, Hepatocellular" 17188425 "miRNA-195 expression is decreased in HCC compared to nontumor liver [59], and is also deleted in lung cancer [65], suggesting it is tumor related. miRNA-195 alters the expression of methyl-CpG binding protein 2 (which alters DNA methylation), the SKI oncogene, and a Bcl-2 like protein [59], suggesting miRNA-195 may act as a tumor suppressor in HCC." epigenetics hsa-mir-127 Colon Neoplasms 17355635 "Human miR-127 is embedded in a CpG island and is silenced in several human cancers including bladder, prostate and colon cancer and has been suggested to play a role as a possible tumour suppressor gene." epigenetics hsa-mir-127 Prostate Neoplasms 17355635 "Human miR-127 is embedded in a CpG island and is silenced in several human cancers including bladder, prostate and colon cancer and has been suggested to play a role as a possible tumour suppressor gene." epigenetics hsa-mir-127 Urinary Bladder Cancer 17355635 "Human miR-127 is embedded in a CpG island and is silenced in several human cancers including bladder, prostate and colon cancer and has been suggested to play a role as a possible tumour suppressor gene." epigenetics hsa-mir-29a Lung Neoplasms 17890317 "mir-29 family (29a,b,c) reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B." epigenetics hsa-mir-29b Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. epigenetics hsa-mir-29b-1 Lung Neoplasms 17890317 "mir-29 family (29a,b,c) reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B." epigenetics hsa-mir-29c Lung Neoplasms 17890317 "mir-29 family (29a,b,c) reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B." epigenetics hsa-mir-34b Colorectal Carcinoma 18519671 "Our results suggest that miR-34b/c and BTG4 are novel tumor suppressors in CRC and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC." epigenetics hsa-mir-34c Colorectal Carcinoma 18519671 "Our results suggest that miR-34b/c and BTG4 are novel tumor suppressors in CRC and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC." epigenetics hsa-mir-1 Cardiomegaly 18539123 "Microinjecting fragments of either the coding region or the related microRNA miR-1 led to high levels of expression of homologous RNA, resulting in an epigenetic defect, cardiac hypertrophy, whose efficient hereditary transmission correlated with the presence of miR-1 in the sperm nucleus." epigenetics hsa-mir-34a Neoplasms [unspecific] 18719384 "miR-34a: inactivation, Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer" epigenetics hsa-mir-34b Neoplasms [unspecific] 18768788 miR-34b: were found to undergo specific hypermethylation-associated silencing in cancer cells compared with normal tissues epigenetics hsa-mir-34c Neoplasms [unspecific] 18768788 miR-34c: were found to undergo specific hypermethylation-associated silencing in cancer cells compared with normal tissues epigenetics hsa-mir-9-1 Neoplasms [unspecific] 18768788 miR-9: were found to undergo specific hypermethylation-associated silencing in cancer cells compared with normal tissues epigenetics hsa-mir-9-2 Neoplasms [unspecific] 18768788 miR-9: were found to undergo specific hypermethylation-associated silencing in cancer cells compared with normal tissues epigenetics hsa-mir-9-3 Neoplasms [unspecific] 18768788 miR-9: were found to undergo specific hypermethylation-associated silencing in cancer cells compared with normal tissues epigenetics hsa-mir-126 Neoplasms [unspecific] 19116145 miR-126: a tumor supressor: Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 epigenetics hsa-mir-29b-1 "Leukemia, Myeloid, Acute" 19211935 miR-29b: induces global DNA hypomethylation and tumor suppressor gene re-expression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1 epigenetics hsa-mir-29b-2 "Leukemia, Myeloid, Acute" 19211935 miR-29b: induces global DNA hypomethylation and tumor suppressor gene re-expression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1 epigenetics hsa-mir-107 Pancreatic Neoplasms 19407485 Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. epigenetics hsa-mir-512 Gastric Neoplasms 19503096 Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells. epigenetics hsa-mir-22 "Leukemia, Lymphoblastic, Acute" 19807731 "Thus, accumulation of H3K27triM independent of promoter DNA methylation may be a novel epigenetic mechanism for MIR22 silencing in ALL." epigenetics hsa-mir-124-1 "Carcinoma, Hepatocellular" 19843643 miR-124:miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. epigenetics hsa-mir-124-2 "Carcinoma, Hepatocellular" 19843643 miR-124:miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. epigenetics hsa-mir-124-3 "Carcinoma, Hepatocellular" 19843643 miR-124:miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. epigenetics hsa-mir-203 "Carcinoma, Hepatocellular" 19843643 miR-203:miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. epigenetics hsa-mir-212 Gastric Neoplasms 20020497 miR-212:miR-212 is downregulated and suppresses methyl-CpG-binding protein MeCP2 in human gastric cancer epigenetics hsa-mir-193b Prostate Neoplasms 20073067 miR-193b:miR-193b is an epigenetically regulated putative tumor suppressor in prostate cancer epigenetics hsa-mir-181c Gastric Neoplasms 20080834 miR-181c:Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis. epigenetics hsa-mir-137 "Squamous Cell Carcinoma, Oral" 20197299 miR-137:MicroRNA-137 promoter methylation in oral rinses from patients with squamous cell carcinoma of the head and neck is associated with gender and body mass index epigenetics hsa-mir-148a Lung Neoplasms 20431052 miR-148a:The silencing of microRNA 148a production by DNA hypermethylation is an early event in pancreatic carcinogenesis epigenetics hsa-mir-124-1 Myelodysplastic Syndromes 20448201 miRNA-124:Methylation and silencing of miRNA-124 by EVI1 and self-renewal exhaustion of hematopoietic stem cells in murine myelodysplastic syndrome epigenetics hsa-mir-124-2 Myelodysplastic Syndromes 20448201 miRNA-124:Methylation and silencing of miRNA-124 by EVI1 and self-renewal exhaustion of hematopoietic stem cells in murine myelodysplastic syndrome epigenetics hsa-mir-124-3 Myelodysplastic Syndromes 20448201 miRNA-124:Methylation and silencing of miRNA-124 by EVI1 and self-renewal exhaustion of hematopoietic stem cells in murine myelodysplastic syndrome epigenetics hsa-mir-27a Pancreatic Neoplasms 20488920 "microRNA-27a:Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a" epigenetics hsa-mir-206 Waldenstrom Macroglobulinemia 20519629 miR-206:Waldenstr?m macroglobulinemia (WM) cells present with increased expression of microRNA-206 (miRNA-206) and reduced expression of miRNA-9 epigenetics hsa-mir-9-1 Waldenstrom Macroglobulinemia 20519629 miR-9:Waldenstr?m macroglobulinemia (WM) cells present with increased expression of microRNA-206 (miRNA-206) and reduced expression of miRNA-9 epigenetics hsa-mir-9-2 Waldenstrom Macroglobulinemia 20519629 miR-9:Waldenstr?m macroglobulinemia (WM) cells present with increased expression of microRNA-206 (miRNA-206) and reduced expression of miRNA-9 epigenetics hsa-mir-152 "Carcinoma, Hepatocellular" 20578129 microRNA-152:a tumor-suppressive role of miR-152 in the epigenetic aberration of HBV-related HCC epigenetics hsa-mir-181b-1 Inflammation 20797623 miR-181b-1:STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer epigenetics hsa-mir-181b-1 Neoplasms [unspecific] 20797623 miR-181b-1:STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer epigenetics hsa-mir-21 Inflammation 20797623 miR-21:STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer epigenetics hsa-mir-21 Neoplasms [unspecific] 20797623 miR-21:STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer epigenetics hsa-mir-34b Gastric Neoplasms 20924086 "These results suggest that miR-34b and miR-34c are novel tumor suppressors frequently silenced by DNA methylation in GC, that methylation of miR-34b/c is involved in an epigenetic field defect and that the methylation might be a predictive marker of GC risk." epigenetics hsa-mir-34c Gastrointestinal Neoplasms 20924086 "These results suggest that miR-34b and miR-34c are novel tumor suppressors frequently silenced by DNA methylation in GC, that methylation of miR-34b/c is involved in an epigenetic field defect and that the methylation might be a predictive marker of GC risk." epigenetics hsa-mir-375 Breast Neoplasms 20978187 Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells. epigenetics hsa-mir-212 Gastrointestinal Neoplasms 21053104 "The conclusion could be deduced from the study that decreased expression of miR-212 may be due to hypermethylation of CPI in gastric cancer cells, and miR-212 might act on the progression of gastric cancer through the potential target gene Myc." epigenetics hsa-mir-1224 Urinary Bladder Cancer 21138856 hypermethylation was more frequent and dense in CpG shores than islands epigenetics hsa-mir-1227 Urinary Bladder Cancer 21138856 hypermethylation was more frequent and dense in CpG shores than islands epigenetics hsa-mir-1229 Urinary Bladder Cancer 21138856 hypermethylation was more frequent and dense in CpG shores than islands epigenetics hsa-mir-149 Urinary Bladder Cancer 21138856 hypermethylation was more frequent and dense in CpG shores than islands epigenetics hsa-mir-210 Urinary Bladder Cancer 21138856 hypermethylation was more frequent and dense in CpG shores than islands epigenetics hsa-mir-212 Urinary Bladder Cancer 21138856 hypermethylation was more frequent and dense in CpG shores than islands epigenetics hsa-mir-328 Urinary Bladder Cancer 21138856 hypermethylation was more frequent and dense in CpG shores than islands epigenetics hsa-mir-503 Urinary Bladder Cancer 21138856 hypermethylation was more frequent and dense in CpG shores than islands epigenetics hsa-mir-9-1 Urinary Bladder Cancer 21138856 hypermethylation was more frequent and dense in CpG shores than islands epigenetics hsa-mir-9-2 Urinary Bladder Cancer 21138856 hypermethylation was more frequent and dense in CpG shores than islands epigenetics hsa-mir-9-3 Urinary Bladder Cancer 21138856 hypermethylation was more frequent and dense in CpG shores than islands epigenetics hsa-mir-373 Cholangiocarcinoma 21165562 Methyl-CpG binding protein MBD2 is implicated in methylation-mediated suppression of miR-373 in hilar Cholangiocarcinoma. epigenetics hsa-mir-126 Systemic Lupus Erythematosus 21165896 MicroRNA-126 regulates DNA methylation in CD4(+) T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1. epigenetics hsa-mir-129-2 Gastric Neoplasms 21213213 "upstream CpG-rich regions of mir-34b and mir-129-2 are frequently methylated in gastric cancer tissues compared with adjacent normal tissues, and their methylation status correlated inversely with their expression patterns." epigenetics hsa-mir-34b Gastric Neoplasms 21213213 "upstream CpG-rich regions of mir-34b and mir-129-2 are frequently methylated in gastric cancer tissues compared with adjacent normal tissues, and their methylation status correlated inversely with their expression patterns." epigenetics hsa-mir-34a Breast Neoplasms 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34a "Carcinoma, Renal Cell" 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34a Colorectal Carcinoma 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34a Ovarian Neoplasms 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34a Pancreatic Neoplasms 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34a Sarcoma [unspecific] 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34a Urinary Bladder Cancer 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34b Breast Neoplasms 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34b "Carcinoma, Renal Cell" 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34b Colorectal Carcinoma 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34b Ovarian Neoplasms 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34b Pancreatic Neoplasms 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34b Sarcoma [unspecific] 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34b Urinary Bladder Cancer 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34c Breast Neoplasms 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34c "Carcinoma, Renal Cell" 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34c Colorectal Carcinoma 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34c Ovarian Neoplasms 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34c Pancreatic Neoplasms 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34c Sarcoma [unspecific] 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-34c Urinary Bladder Cancer 21225432 "Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas." epigenetics hsa-mir-196b Prostate Neoplasms 21255435 "We find miR-205, miR-21, and miR-196b to be epigenetically repressed, and miR-615 epigenetically activated in prostate cancer cells." epigenetics hsa-mir-205 Prostate Neoplasms 21255435 "We find miR-205, miR-21, and miR-196b to be epigenetically repressed, and miR-615 epigenetically activated in prostate cancer cells." epigenetics hsa-mir-21 Prostate Neoplasms 21255435 "We find miR-205, miR-21, and miR-196b to be epigenetically repressed, and miR-615 epigenetically activated in prostate cancer cells." epigenetics hsa-mir-29b-1 Atherosclerosis 21266537 "OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases." epigenetics hsa-mir-29b-2 Atherosclerosis 21266537 "OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases." epigenetics hsa-mir-335 Breast Neoplasms 21289068 MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer. epigenetics hsa-mir-200b Neoplasms [unspecific] 21292642 Depletion of miR-200 in arsenite-transformed cells involved induction of the EMT-inducing transcription factors ZEB1 (zinc-finger E-box-binding homeobox factor 1) and ZEB2 and increased methylation of miR-200 promoters. epigenetics hsa-mir-199a-1 Breast Neoplasms 21317930 "Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells" epigenetics hsa-mir-199a-1 "Carcinoma, Lung, Non-Small-Cell" 21317930 "Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells" epigenetics hsa-mir-199a-1 Colorectal Carcinoma 21317930 "Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells" epigenetics hsa-mir-199a-2 Breast Neoplasms 21317930 "Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells" epigenetics hsa-mir-199a-2 "Carcinoma, Lung, Non-Small-Cell" 21317930 "Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells" epigenetics hsa-mir-199a-2 Colorectal Carcinoma 21317930 "Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells" epigenetics hsa-mir-199b Breast Neoplasms 21317930 "Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells" epigenetics hsa-mir-199b "Carcinoma, Lung, Non-Small-Cell" 21317930 "Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells" epigenetics hsa-mir-199b Colorectal Carcinoma 21317930 "Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells" epigenetics hsa-mir-34a Breast Neoplasms 21317930 "Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells" epigenetics hsa-mir-34a "Carcinoma, Lung, Non-Small-Cell" 21317930 "Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells" epigenetics hsa-mir-34a Colorectal Carcinoma 21317930 "Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells" epigenetics hsa-mir-203 "Leukemia, Myeloid, Acute" 21323860 The frequent hsa-miR-203 methylation in lymphoid malignancies suggested a pathogenetic role of hsa-miR-203 methylation. epigenetics hsa-mir-1-1 Colorectal Carcinoma 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-1-1 Endometrial Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-1-1 Gastrointestinal Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-124-1 Colorectal Carcinoma 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-124-1 Endometrial Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-124-1 Gastrointestinal Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-124-2 Colorectal Carcinoma 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-124-2 Endometrial Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-124-2 Gastrointestinal Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-124-3 Colorectal Carcinoma 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-124-3 Endometrial Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-124-3 Gastrointestinal Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-148a Colorectal Carcinoma 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-148a Endometrial Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-148a Gastrointestinal Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-152 Colorectal Carcinoma 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-152 Endometrial Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-152 Gastrointestinal Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-18b Colorectal Carcinoma 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-18b Endometrial Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-18b Gastrointestinal Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-200a Colorectal Carcinoma 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-200a Endometrial Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-200a Gastrointestinal Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-208a Colorectal Carcinoma 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-208a Endometrial Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-208a Gastrointestinal Neoplasms 21327300 "Compared with the respective normal tissues, the predominant alteration in tumor tissues was increased methylation for the miRNAs 1-1, 124a-1, 124a-2, 124a-3, 148a, 152, and 18b; decreased methylation for 200a and 208a;" epigenetics hsa-mir-145 Prostate Neoplasms 21349819 this is the first report documenting that downregulation of miR-145 is through DNA methylation and p53 mutation pathways in prostate cancer. epigenetics hsa-mir-124-1 Gastric Neoplasms 21365509 "Significant associations were found between hypermethylation of hsa-miR-124a and tumor size, differentiation, lymphatic metastasis, and invasion depth(P<0.01)." epigenetics hsa-mir-124-2 Gastric Neoplasms 21365509 "Significant associations were found between hypermethylation of hsa-miR-124a and tumor size, differentiation, lymphatic metastasis, and invasion depth(P<0.01)." epigenetics hsa-mir-124-3 Gastric Neoplasms 21365509 "Significant associations were found between hypermethylation of hsa-miR-124a and tumor size, differentiation, lymphatic metastasis, and invasion depth(P<0.01)." epigenetics hsa-mir-34b "Carcinoma, Lung, Non-Small-Cell" 21383543 DNA hypermethylation of microRNA-34b/c has prognostic value for stage ¢ñ non-small cell lung cancer. epigenetics hsa-mir-34c "Carcinoma, Lung, Non-Small-Cell" 21383543 DNA hypermethylation of microRNA-34b/c has prognostic value for stage ¢ñ non-small cell lung cancer. epigenetics hsa-mir-199a-1 Testicular Neoplasms 21383689 "PODXL is a downstream effector mediating the action of miR199a-5p. This report identifies DNA methylation, miR-199a dysregulation and PODXL as critical factors in tumor malignancy." epigenetics hsa-mir-199a-2 Testicular Neoplasms 21383689 "PODXL is a downstream effector mediating the action of miR199a-5p. This report identifies DNA methylation, miR-199a dysregulation and PODXL as critical factors in tumor malignancy." epigenetics hsa-mir-193a "Leukemia, Myeloid, Acute" 21399664 MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia. epigenetics hsa-mir-137 "Squamous Cell Carcinoma, Head and Neck" 21425146 MicroRNA-137 promoter methylation is associated with poorer overall survival in patients with squamous cell carcinoma of the head and neck. epigenetics hsa-mir-203 Lymphoma 21454413 Epigenetic silencing of microRNA-203 dysregulates ABL1 expression and drives Helicobacter-associated gastric lymphomagenesis. epigenetics hsa-mir-203 Urinary Bladder Cancer 21461574 hypermethylation of miR-124a and miR-203 in the precursor lesions compared to the control samples epigenetics hsa-mir-181a-2 "Carcinoma, Hepatocellular" 21464043 "HBx promotes stemness by activating {beta}-catenin and epigenetic up-regulation of miR-181, both of which target EpCAM." epigenetics hsa-mir-181b-1 "Carcinoma, Hepatocellular" 21464043 "HBx promotes stemness by activating {beta}-catenin and epigenetic up-regulation of miR-181, both of which target EpCAM." epigenetics hsa-mir-181b-2 "Carcinoma, Hepatocellular" 21464043 "HBx promotes stemness by activating {beta}-catenin and epigenetic up-regulation of miR-181, both of which target EpCAM." epigenetics hsa-mir-181c "Carcinoma, Hepatocellular" 21464043 "HBx promotes stemness by activating {beta}-catenin and epigenetic up-regulation of miR-181, both of which target EpCAM." epigenetics hsa-mir-181d "Carcinoma, Hepatocellular" 21464043 "HBx promotes stemness by activating {beta}-catenin and epigenetic up-regulation of miR-181, both of which target EpCAM." epigenetics hsa-mir-375 Esophageal Neoplasms 21533613 Epigenetic Silencing of MicroRNA-375 Regulates PDK1 Expression in Esophageal Cancer epigenetics hsa-mir-126 Systemic Lupus Erythematosus 21538319 MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1. epigenetics hsa-mir-24-1 "Leukemia, Myeloid, Acute" 21544199 miR-124-1 is epigenetically inactivated in Haematological Malignancies. epigenetics hsa-mir-24-1 Lymphoma 21544199 miR-124-1 is epigenetically inactivated in Haematological Malignancies. epigenetics hsa-mir-24-1 Multiple Myeloma 21544199 miR-124-1 is epigenetically inactivated in Haematological Malignancies. epigenetics hsa-mir-129-2 Esophageal Neoplasms 21547903 "The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01)." epigenetics hsa-mir-129-2 "Squamous Cell Carcinoma, Esophageal" 21547903 "The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01)." epigenetics hsa-mir-34a Esophageal Neoplasms 21547903 "The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01)." epigenetics hsa-mir-34a "Squamous Cell Carcinoma, Esophageal" 21547903 "The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01)." epigenetics hsa-mir-34b Esophageal Neoplasms 21547903 "The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01)." epigenetics hsa-mir-34b "Squamous Cell Carcinoma, Esophageal" 21547903 "The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01)." epigenetics hsa-mir-34c Esophageal Neoplasms 21547903 "The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01)." epigenetics hsa-mir-34c "Squamous Cell Carcinoma, Esophageal" 21547903 "The methylation ratio of miR-34a, miR-34b/c and miR-129-2 is 66.7%(36/54), 40.7%(22/54), and 96.3%(52/54) respectively in ESCC, which are significantly higher than that in corresponding non-tumor tissues(p<0.01)." epigenetics hsa-mir-10b Gastric Neoplasms 21562367 "miR-10b methylation may be a useful molecular biomarker for assessing the risk of gastric cancer development, and modulation of miR-10b may represent a therapeutic approach for treating gastric cancer." epigenetics hsa-mir-34b Colorectal Carcinoma 21610744 Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer. epigenetics hsa-mir-34c Colorectal Carcinoma 21610744 Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer. epigenetics hsa-mir-132 Pancreatic Neoplasms 21665894 Downregulation of miR-132 by promoter methylation contributes to pancreatic cancer development. epigenetics hsa-mir-345 Colorectal Carcinoma 21665895 "MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer." epigenetics hsa-mir-34b Mesothelioma 21673066 Epigenetic Silencing of MicroRNA-34b/c Plays an Important Role in the Pathogenesis of Malignant Pleural Mesothelioma. epigenetics hsa-mir-34c Mesothelioma 21673066 Epigenetic Silencing of MicroRNA-34b/c Plays an Important Role in the Pathogenesis of Malignant Pleural Mesothelioma. epigenetics hsa-mir-221 Breast Neoplasms 21673316 TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer. epigenetics hsa-mir-196a-2 "Carcinoma, Hepatocellular" 21692953 The CC genotype of the miR-196a-2 rs11614913 polymorphism is associated with increased risk of HCC development in this Turkish population. epigenetics hsa-mir-126 "Carcinoma, Lung, Non-Small-Cell" 21702040 mir-34b and mir-126 were silenced by DNA methylation. epigenetics hsa-mir-34b "Carcinoma, Lung, Non-Small-Cell" 21702040 mir-34b and mir-126 were silenced by DNA methylation. epigenetics hsa-mir-143 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 21706045 Methylation-mediated repression of microRNA-143 enhances MLL-AF4 oncogene expression. epigenetics hsa-mir-373 Liver Neoplasms 21706058 "Thus, histone deacetylation of CDH1 and downregulation of miR-373, together with the previously demonstrated hypermethylation of CDH1 by HBx, may be important for the understanding of HBV-related carcinogenesis." epigenetics hsa-mir-203 Multiple Myeloma 21707582 MIR203 is epigeneticlly silenced in multiple myeloma. epigenetics hsa-mir-373 Colorectal Carcinoma 21785829 Epigenetic silencing of microRNA-373 plays an important role in regulating cell proliferation in colon cancer. epigenetics hsa-mir-200a "Carcinoma, Hepatocellular" 21837748 The histone deacetylase 4/Sp1/miR-200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma. epigenetics hsa-mir-152 Endometrial Neoplasms 21868754 miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer. epigenetics hsa-mir-17 "Leukemia, Myeloid, Acute" 21897363 We propose that upon macrophage differentiation PU.1 represses the miR-17-92 cluster promoter by an Egr-2/Jarid1b-mediated H3K4 demethylation mechanism whose deregulation may contribute to leukaemic states. epigenetics hsa-mir-18 "Leukemia, Myeloid, Acute" 21897363 We propose that upon macrophage differentiation PU.1 represses the miR-17-92 cluster promoter by an Egr-2/Jarid1b-mediated H3K4 demethylation mechanism whose deregulation may contribute to leukaemic states. epigenetics hsa-mir-19a "Leukemia, Myeloid, Acute" 21897363 We propose that upon macrophage differentiation PU.1 represses the miR-17-92 cluster promoter by an Egr-2/Jarid1b-mediated H3K4 demethylation mechanism whose deregulation may contribute to leukaemic states. epigenetics hsa-mir-19b-1 "Leukemia, Myeloid, Acute" 21897363 We propose that upon macrophage differentiation PU.1 represses the miR-17-92 cluster promoter by an Egr-2/Jarid1b-mediated H3K4 demethylation mechanism whose deregulation may contribute to leukaemic states. epigenetics hsa-mir-20a "Leukemia, Myeloid, Acute" 21897363 We propose that upon macrophage differentiation PU.1 represses the miR-17-92 cluster promoter by an Egr-2/Jarid1b-mediated H3K4 demethylation mechanism whose deregulation may contribute to leukaemic states. epigenetics hsa-mir-92-1 "Leukemia, Myeloid, Acute" 21897363 We propose that upon macrophage differentiation PU.1 represses the miR-17-92 cluster promoter by an Egr-2/Jarid1b-mediated H3K4 demethylation mechanism whose deregulation may contribute to leukaemic states. epigenetics hsa-mir-124-1 Gastric Neoplasms 21914401 The hypermethylation of miRNA-34b/c and miRNA-124a gene promoters may play a crucial role in the occurrence and development of gastric carcinoma. epigenetics hsa-mir-34b Gastric Neoplasms 21914401 The hypermethylation of miRNA-34b/c and miRNA-124a gene promoters may play a crucial role in the occurrence and development of gastric carcinoma. epigenetics hsa-mir-34c Gastric Neoplasms 21914401 The hypermethylation of miRNA-34b/c and miRNA-124a gene promoters may play a crucial role in the occurrence and development of gastric carcinoma. epigenetics hsa-mir-124-2 "Carcinoma, Lung, Non-Small-Cell" 21917081 "The methylation of mir-9-3, -124-2, and -124-3 was individually associated with an advanced T factor independently of age, sex, and smoking habit." epigenetics hsa-mir-124-3 "Carcinoma, Lung, Non-Small-Cell" 21917081 "The methylation of mir-9-3, -124-2, and -124-3 was individually associated with an advanced T factor independently of age, sex, and smoking habit." epigenetics hsa-mir-9-3 "Carcinoma, Lung, Non-Small-Cell" 21917081 "The methylation of mir-9-3, -124-2, and -124-3 was individually associated with an advanced T factor independently of age, sex, and smoking habit." epigenetics hsa-mir-139 Gastric Neoplasms 21925125 HER2 Interacts with CD44 to Upregulate CXCR4 via Epigenetic Silencing of microRNA-139 in Gastric Cancer Cells. epigenetics hsa-mir-9-1 Gastric Neoplasms 21931274 "In this study, we demonstrate that three independent genetic loci encoding for miR-9 (miR-9-1, miR-9-2 and miR-9-3) are simultaneously modified by DNA methylation in gastric cancer cells. Methylation-mediated silencing of these three miR-9 genes can be reactivated in gastric cancer cells through 5-Aza-dC treatment." epigenetics hsa-mir-9-2 Gastric Neoplasms 21931274 "In this study, we demonstrate that three independent genetic loci encoding for miR-9 (miR-9-1, miR-9-2 and miR-9-3) are simultaneously modified by DNA methylation in gastric cancer cells. Methylation-mediated silencing of these three miR-9 genes can be reactivated in gastric cancer cells through 5-Aza-dC treatment." epigenetics hsa-mir-9-3 Gastric Neoplasms 21931274 "In this study, we demonstrate that three independent genetic loci encoding for miR-9 (miR-9-1, miR-9-2 and miR-9-3) are simultaneously modified by DNA methylation in gastric cancer cells. Methylation-mediated silencing of these three miR-9 genes can be reactivated in gastric cancer cells through 5-Aza-dC treatment." epigenetics hsa-mir-129-1 Thyroid Neoplasms 21946411 "Two HDACi, Trichostatin A and vorinostat, induced miR-129-5p overexpression, histone acetylation and cell death. In addition, miR-129-5p alone was sufficient to induce cell death and knockdown experiments showed that expression of this miRNA was required for HDACi-induced cell death. Moreover, miR-129-5p was also able to improve the anti-proliferative effects of other cancer drugs such as etoposide or HAMLET (human alpha lactalbumin made letal for tumor cells). Taken together, the data show that miR-129-5p is involved in the antitumor activity of HDACi and highlight that miRNA-driven cell death may be an efficient approach to cancer treatment." epigenetics hsa-mir-129-2 Thyroid Neoplasms 21946411 "Two HDACi, Trichostatin A and vorinostat, induced miR-129-5p overexpression, histone acetylation and cell death. In addition, miR-129-5p alone was sufficient to induce cell death and knockdown experiments showed that expression of this miRNA was required for HDACi-induced cell death. Moreover, miR-129-5p was also able to improve the anti-proliferative effects of other cancer drugs such as etoposide or HAMLET (human alpha lactalbumin made letal for tumor cells). Taken together, the data show that miR-129-5p is involved in the antitumor activity of HDACi and highlight that miRNA-driven cell death may be an efficient approach to cancer treatment." epigenetics hsa-mir-129-2 Gastric Neoplasms 21960261 "The methylation-silenced expression of the miRNA could be reactivated in gastric cancer cells by treatment with demethylating drugs in a time-dependent manner.Analysis of the methylation status of these miRNAs showed that the upstream CpG-rich regions of mir-34b and mir-129-2 are frequently methylated in gastric cancer tissues compared to adjacent normal tissues, and their methylation status correlated inversely with their expression patterns. The expression of miR-34b and miR-129-3p was downregulated by DNA hypermethylation in primary gastric cancers, and the low expression was associated with poor clinicopathological features." epigenetics hsa-mir-34b Gastric Neoplasms 21960261 "The methylation-silenced expression of the miRNA could be reactivated in gastric cancer cells by treatment with demethylating drugs in a time-dependent manner.Analysis of the methylation status of these miRNAs showed that the upstream CpG-rich regions of mir-34b and mir-129-2 are frequently methylated in gastric cancer tissues compared to adjacent normal tissues, and their methylation status correlated inversely with their expression patterns. The expression of miR-34b and miR-129-3p was downregulated by DNA hypermethylation in primary gastric cancers, and the low expression was associated with poor clinicopathological features." epigenetics hsa-mir-185 Glioma 21962230 MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma. epigenetics hsa-let-7e Breast Neoplasms 21969366 Jumonji/Arid1 B (JARID1B) promotes breast tumor cell cycle progression through epigenetic repression of micro RNA let-7e. epigenetics hsa-mir-191 "Carcinoma, Hepatocellular" 21969817 Hypomethylation of the hsa-miR-191 Locus Causes High Expression of hsa-miR-191 and Promotes the Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma. epigenetics hsa-mir-34b "Carcinoma, Lung, Small-Cell" 22047961 Frequent methylation and oncogenic role of microRNA-34b/c in small-cell lung cancer. epigenetics hsa-mir-34c "Carcinoma, Lung, Small-Cell" 22047961 Frequent methylation and oncogenic role of microRNA-34b/c in small-cell lung cancer. epigenetics hsa-mir-29a Influenza 22072783 Epigenetic Changes Mediated by miR29 Activate Cyclooxygenase-2 and Interferon Production during Viral Infection. epigenetics hsa-mir-34c Breast Neoplasms 22074923 MiR-34c down-regulation via DNA methylation promotes self-renewal and epithelial-mesenchymal transition in breast tumor-initiating cells. epigenetics hsa-mir-34b Neoplasms [unspecific] 22082000 "miR-34b/c were homozygously methylated in HEL cells but heterozygously in MEG-01. In HEL cells, homozygous miR-34b/c methylation was associated with miR silencing, and 5-aza-2'-deoxycytidine treatment led to re-expression of both miR-34b and miR-34c, consistent with that both miRs are under the regulation of the same promoter CpG island. miR-34a was heterozygously methylated in MEG-01 and K-562. miR-203 was completely unmethylated in K-562 and SET-2 but no MSP amplification was found in both HEL and MEG-01, suggestive of miR deletion. In primary samples, four each had miR-34b/c and -203 methylation, in which two had concomitant methylation of miR-34b/c and -203. miR-34a was methylated in one patient and none had methylation of miR-124-1." epigenetics hsa-mir-34c Neoplasms [unspecific] 22082000 "miR-34b/c were homozygously methylated in HEL cells but heterozygously in MEG-01. In HEL cells, homozygous miR-34b/c methylation was associated with miR silencing, and 5-aza-2'-deoxycytidine treatment led to re-expression of both miR-34b and miR-34c, consistent with that both miRs are under the regulation of the same promoter CpG island. miR-34a was heterozygously methylated in MEG-01 and K-562. miR-203 was completely unmethylated in K-562 and SET-2 but no MSP amplification was found in both HEL and MEG-01, suggestive of miR deletion. In primary samples, four each had miR-34b/c and -203 methylation, in which two had concomitant methylation of miR-34b/c and -203. miR-34a was methylated in one patient and none had methylation of miR-124-1." epigenetics hsa-mir-369 "Leukemia, Myeloid, Chronic" 22089542 "The CpG islands in the upstream regions of miR-663, miR-369, miR-615, and miR-410, and promoter activity was detected in the upstream region of pre-miR-663. We found that a decrease in methylation of a CpG island could up-regulate the expression of miR-663, suggesting that miR-663 could be regulated by DNA methylation." epigenetics hsa-mir-410 "Leukemia, Myeloid, Chronic" 22089542 "The CpG islands in the upstream regions of miR-663, miR-369, miR-615, and miR-410, and promoter activity was detected in the upstream region of pre-miR-663. We found that a decrease in methylation of a CpG island could up-regulate the expression of miR-663, suggesting that miR-663 could be regulated by DNA methylation." epigenetics hsa-mir-615 "Leukemia, Myeloid, Chronic" 22089542 "The CpG islands in the upstream regions of miR-663, miR-369, miR-615, and miR-410, and promoter activity was detected in the upstream region of pre-miR-663. We found that a decrease in methylation of a CpG island could up-regulate the expression of miR-663, suggesting that miR-663 could be regulated by DNA methylation." epigenetics hsa-mir-663a "Leukemia, Myeloid, Chronic" 22089542 "The CpG islands in the upstream regions of miR-663, miR-369, miR-615, and miR-410, and promoter activity was detected in the upstream region of pre-miR-663. We found that a decrease in methylation of a CpG island could up-regulate the expression of miR-663, suggesting that miR-663 could be regulated by DNA methylation." epigenetics hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 22096249 "Histone deacetylases mediate the silencing of miR-15a, miR-16 and miR-29b in chronic lymphocytic leukemia." epigenetics hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 22096249 "Histone deacetylases mediate the silencing of miR-15a, miR-16 and miR-29b in chronic lymphocytic leukemia." epigenetics hsa-mir-16-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 22096249 "Histone deacetylases mediate the silencing of miR-15a, miR-16 and miR-29b in chronic lymphocytic leukemia." epigenetics hsa-mir-29b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 22096249 "Histone deacetylases mediate the silencing of miR-15a, miR-16 and miR-29b in chronic lymphocytic leukemia." epigenetics hsa-mir-29b-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 22096249 "Histone deacetylases mediate the silencing of miR-15a, miR-16 and miR-29b in chronic lymphocytic leukemia." epigenetics hsa-mir-212 "Carcinoma, Lung, Non-Small-Cell" 22110741 "We identified histone modifications rather than DNA hypermethylation as epigenetic events that regulate miR-212 levels in NSCLC. Moreover, we found that miR-212 silencing in vivo is closely associated with the severity of the disease." epigenetics hsa-mir-193a "Carcinoma, Hepatocellular" 22117060 DNA methylation regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via SRSF2. epigenetics hsa-mir-127 "Carcinoma, Oral" 22132151 "MiR-375 is repressed and miR-127 activated in OSCC, and we confirm previous reports of miR-137 hypermethylation in oral cancer. The miR-200 s/miR-205 were epigenetically activated in tumors vs normal tissues, but repressed in the absence of DNA hypermethylation specifically in CD44(high) oral CSCs. Aberrant miR-375 and miR-200a expression and miR-200c-141 methylation could be detected in and distinguish OSCC patient oral rinse and saliva from healthy volunteers." epigenetics hsa-mir-137 "Carcinoma, Oral" 22132151 "MiR-375 is repressed and miR-127 activated in OSCC, and we confirm previous reports of miR-137 hypermethylation in oral cancer. The miR-200 s/miR-205 were epigenetically activated in tumors vs normal tissues, but repressed in the absence of DNA hypermethylation specifically in CD44(high) oral CSCs. Aberrant miR-375 and miR-200a expression and miR-200c-141 methylation could be detected in and distinguish OSCC patient oral rinse and saliva from healthy volunteers." epigenetics hsa-mir-141 "Carcinoma, Oral" 22132151 "MiR-375 is repressed and miR-127 activated in OSCC, and we confirm previous reports of miR-137 hypermethylation in oral cancer. The miR-200 s/miR-205 were epigenetically activated in tumors vs normal tissues, but repressed in the absence of DNA hypermethylation specifically in CD44(high) oral CSCs. Aberrant miR-375 and miR-200a expression and miR-200c-141 methylation could be detected in and distinguish OSCC patient oral rinse and saliva from healthy volunteers." epigenetics hsa-mir-200a "Carcinoma, Oral" 22132151 "MiR-375 is repressed and miR-127 activated in OSCC, and we confirm previous reports of miR-137 hypermethylation in oral cancer. The miR-200 s/miR-205 were epigenetically activated in tumors vs normal tissues, but repressed in the absence of DNA hypermethylation specifically in CD44(high) oral CSCs. Aberrant miR-375 and miR-200a expression and miR-200c-141 methylation could be detected in and distinguish OSCC patient oral rinse and saliva from healthy volunteers." epigenetics hsa-mir-200c "Carcinoma, Oral" 22132151 "MiR-375 is repressed and miR-127 activated in OSCC, and we confirm previous reports of miR-137 hypermethylation in oral cancer. The miR-200 s/miR-205 were epigenetically activated in tumors vs normal tissues, but repressed in the absence of DNA hypermethylation specifically in CD44(high) oral CSCs. Aberrant miR-375 and miR-200a expression and miR-200c-141 methylation could be detected in and distinguish OSCC patient oral rinse and saliva from healthy volunteers." epigenetics hsa-mir-375 "Carcinoma, Oral" 22132151 "MiR-375 is repressed and miR-127 activated in OSCC, and we confirm previous reports of miR-137 hypermethylation in oral cancer. The miR-200 s/miR-205 were epigenetically activated in tumors vs normal tissues, but repressed in the absence of DNA hypermethylation specifically in CD44(high) oral CSCs. Aberrant miR-375 and miR-200a expression and miR-200c-141 methylation could be detected in and distinguish OSCC patient oral rinse and saliva from healthy volunteers." epigenetics hsa-mir-9-1 "Squamous Cell Carcinoma, Oral" 22133638 Methylation of microRNA-9 is a specific and sensitive biomarker for oral and oropharyngeal squamous cell carcinomas. epigenetics hsa-mir-9-3 "Squamous Cell Carcinoma, Oral" 22133638 Methylation of microRNA-9 is a specific and sensitive biomarker for oral and oropharyngeal squamous cell carcinomas. epigenetics hsa-mir-148a Gastric Neoplasms 22167392 MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in gastric cancer. epigenetics hsa-mir-29b Cardiovascular Diseases [unspecific] 22226905 This article is part of a Special Issue entitled OxLDL causes both epigenetic modification and signaling regulation on the microRNA-29b gene: Novel mechanisms for cardiovascular diseases. epigenetics hsa-mir-200b Breast Neoplasms 22231446 Methylation of functional promoters of the Hsa-mir-200b is associated with metastasis or hormone receptor status in advanced breast cancer. epigenetics hsa-mir-519d "Carcinoma, Hepatocellular" 22262409 "In hepatocellular carcinoma miR-519d is upregulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2." epigenetics hsa-mir-125b-1 Breast Neoplasms 22277129 "We observed a significant reduction on the expression of miR-125b1 in cancer cells in comparison with controls, suggesting that DNA methylation at the CpG island might reduce miR-125b1 expression." epigenetics hsa-mir-193a "Carcinoma, Lung, Non-Small-Cell" 22282464 Genome-Wide miRNA Expression Profiling Identifies miR-9-3 and miR-193a as Targets for DNA Methylation in Non-Small Cell Lung Cancers. epigenetics hsa-mir-9-3 "Carcinoma, Lung, Non-Small-Cell" 22282464 Genome-Wide miRNA Expression Profiling Identifies miR-9-3 and miR-193a as Targets for DNA Methylation in Non-Small Cell Lung Cancers. epigenetics hsa-mir-31 Breast Neoplasms 22289355 miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer. epigenetics hsa-mir-152 Atherosclerosis 22295098 MicroRNA-152 mediates DNMT1-regulated DNA methylation in the estrogen receptor ¦Á gene. epigenetics hsa-mir-17 Colorectal Carcinoma 22308110 Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. epigenetics hsa-mir-18a Colorectal Carcinoma 22308110 Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. epigenetics hsa-mir-19a Colorectal Carcinoma 22308110 Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. epigenetics hsa-mir-19b-1 Colorectal Carcinoma 22308110 Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. epigenetics hsa-mir-20a Colorectal Carcinoma 22308110 Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. epigenetics hsa-mir-92a-1 Colorectal Carcinoma 22308110 Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. epigenetics hsa-mir-132 Prostate Neoplasms 22310291 DNA methylation silences miR-132 in prostate cancer. epigenetics hsa-mir-34a Prostate Neoplasms 22347519 Epigenetic silencing of miR-34a in human prostate cancer cells and tumor tissue specimens can be reversed by BR-DIM treatment. epigenetics hsa-let-7c "Carcinoma, Hepatocellular" 22370893 "Enhancer of zeste homolog 2 (EZH2) epigenetically silences multiple tumor suppressor miRNAs (miR-139-5p, miR-125b, miR-101, let-7c, and miR-200b) to promote liver cancer metastasis." epigenetics hsa-mir-101-1 "Carcinoma, Hepatocellular" 22370893 "Enhancer of zeste homolog 2 (EZH2) epigenetically silences multiple tumor suppressor miRNAs (miR-139-5p, miR-125b, miR-101, let-7c, and miR-200b) to promote liver cancer metastasis." epigenetics hsa-mir-125b-1 "Carcinoma, Hepatocellular" 22370893 "Enhancer of zeste homolog 2 (EZH2) epigenetically silences multiple tumor suppressor miRNAs (miR-139-5p, miR-125b, miR-101, let-7c, and miR-200b) to promote liver cancer metastasis." epigenetics hsa-mir-125b-2 "Carcinoma, Hepatocellular" 22370893 "Enhancer of zeste homolog 2 (EZH2) epigenetically silences multiple tumor suppressor miRNAs (miR-139-5p, miR-125b, miR-101, let-7c, and miR-200b) to promote liver cancer metastasis." epigenetics hsa-mir-139 "Carcinoma, Hepatocellular" 22370893 "Enhancer of zeste homolog 2 (EZH2) epigenetically silences multiple tumor suppressor miRNAs (miR-139-5p, miR-125b, miR-101, let-7c, and miR-200b) to promote liver cancer metastasis." epigenetics hsa-mir-200b "Carcinoma, Hepatocellular" 22370893 "Enhancer of zeste homolog 2 (EZH2) epigenetically silences multiple tumor suppressor miRNAs (miR-139-5p, miR-125b, miR-101, let-7c, and miR-200b) to promote liver cancer metastasis." epigenetics hsa-mir-675 Eosinophilic Esophagitis 22391115 EoE remission induced a single miRNA (miR-675) likely to be involved in DNA methylation. epigenetics hsa-mir-203 Breast Neoplasms 22393463 Epigenetic Silencing of miR-203 Upregulates SNAI2 and Contributes to the Invasiveness of Malignant Breast Cancer Cells. epigenetics hsa-mir-199b Medulloblastoma 22411914 "The micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma." epigenetics hsa-mir-224 "Carcinoma, Hepatocellular" 22459148 MicroRNA-224 is up-regulated in hepatocellular carcinoma through epigenetic mechanisms. epigenetics hsa-let-7b Liver Neoplasms 22683924 Downregulation of HMGA2 by the pan-deacetylase inhibitor panobinostat is dependent on hsa-let-7b expression in liver cancer cell lines. epigenetics hsa-mir-137 Gastric Neoplasms 22703336 "Methylation frequency of 5 miR CpG islands (miR-9-1, miR-9-3, miR-137, miR-34b, and miR-210) gradually increased while the proportion of methylated miR-200b gradually decreased during gastric carcinogenesis" epigenetics hsa-mir-210 Gastric Neoplasms 22703336 "Methylation frequency of 5 miR CpG islands (miR-9-1, miR-9-3, miR-137, miR-34b, and miR-210) gradually increased while the proportion of methylated miR-200b gradually decreased during gastric carcinogenesis" epigenetics hsa-mir-34b Gastric Neoplasms 22703336 "Methylation frequency of 5 miR CpG islands (miR-9-1, miR-9-3, miR-137, miR-34b, and miR-210) gradually increased while the proportion of methylated miR-200b gradually decreased during gastric carcinogenesis" epigenetics hsa-mir-9-1 Gastric Neoplasms 22703336 "Methylation frequency of 5 miR CpG islands (miR-9-1, miR-9-3, miR-137, miR-34b, and miR-210) gradually increased while the proportion of methylated miR-200b gradually decreased during gastric carcinogenesis" epigenetics hsa-mir-9-3 Gastric Neoplasms 22703336 "Methylation frequency of 5 miR CpG islands (miR-9-1, miR-9-3, miR-137, miR-34b, and miR-210) gradually increased while the proportion of methylated miR-200b gradually decreased during gastric carcinogenesis" epigenetics hsa-mir-218-1 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. epigenetics hsa-mir-218-2 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. epigenetics hsa-mir-7-1 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. epigenetics hsa-mir-7-2 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. epigenetics hsa-mir-7-3 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. epigenetics hsa-mir-1-1 Colorectal Carcinoma 22766685 Silencing of miR-1-1 and miR-133a-2 cluster expression by DNA hypermethylation in colorectal cancer. epigenetics hsa-mir-133a-1 Colorectal Carcinoma 22766685 Silencing of miR-1-1 and miR-133a-2 cluster expression by DNA hypermethylation in colorectal cancer. epigenetics hsa-mir-133a-2 Colorectal Carcinoma 22766685 Silencing of miR-1-1 and miR-133a-2 cluster expression by DNA hypermethylation in colorectal cancer. epigenetics hsa-mir-340 Neuroblastoma 22797059 miR-340 is upregulated by demethylation of an upstream genomic region that occurs during the process of neuroblastoma cell differentiation induced by all-trans retinoic acid (ATRA). epigenetics hsa-mir-1256 Prostate Neoplasms 22805767 Epigenetic deregulation of miR-29a and miR-1256 by isoflavone contributes to the inhibition of prostate cancer cell growth and invasion. epigenetics hsa-mir-29a Prostate Neoplasms 22805767 Epigenetic deregulation of miR-29a and miR-1256 by isoflavone contributes to the inhibition of prostate cancer cell growth and invasion. epigenetics hsa-mir-124-1 Cholangiocarcinoma 22819820 Epigenetic regulation of miR-124 by Hepatitis C Virus core protein promotes migration and invasion of intrahepatic cholangiocarcinoma cells by targeting SMYD3. epigenetics hsa-mir-124-2 Cholangiocarcinoma 22819820 Epigenetic regulation of miR-124 by Hepatitis C Virus core protein promotes migration and invasion of intrahepatic cholangiocarcinoma cells by targeting SMYD3. epigenetics hsa-mir-149 Colorectal Carcinoma 22821729 SP1 mediates the link between methylation of the tumour suppressor miR-149 and outcome in colorectal cancer. epigenetics hsa-mir-205 Prostate Neoplasms 22869146 Epigenetic-induced repression of microRNA-205 is associated with MED1 activation and a poorer prognosis in localized prostate cancer. epigenetics hsa-mir-124a Colorectal Carcinoma 22870149 The results showed that the methylation of miR-124a and miR-34b/c occured early in colorectal carcinogenesis and certain CRCs may arise from a field defect defined by the epigenetic inactivation of miRs. epigenetics hsa-mir-34b Colorectal Carcinoma 22870149 The results showed that the methylation of miR-124a and miR-34b/c occured early in colorectal carcinogenesis and certain CRCs may arise from a field defect defined by the epigenetic inactivation of miRs. epigenetics hsa-mir-34c Colorectal Carcinoma 22870149 The results showed that the methylation of miR-124a and miR-34b/c occured early in colorectal carcinogenesis and certain CRCs may arise from a field defect defined by the epigenetic inactivation of miRs. epigenetics hsa-mir-141 Esophageal Neoplasms 22921431 Inhibition of SOX17 by MicroRNA-141 and Methylation Activates the WNT Signaling Pathway in Esophageal Cancer. epigenetics hsa-mir-31 Melanoma 22948084 Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma. epigenetics hsa-mir-127 Osteosarcoma 22957032 "Treatment with 4-phenylbutyrate increased acetylation of histones associated with 14q32 miRNAs, but interestingly, robust restoration of 14q32 miRNA expression, attenuation of cMYC expression, and induction of apoptosis required concomitant treatment with 5-Azacytidine, an inhibitor of DNA methylation. combination of these chromatin-modifying drugs may be a useful adjuvant in the treatment of rapidly progressive osteosarcoma." epigenetics hsa-mir-411 Osteosarcoma 22957032 "Treatment with 4-phenylbutyrate increased acetylation of histones associated with 14q32 miRNAs, but interestingly, robust restoration of 14q32 miRNA expression, attenuation of cMYC expression, and induction of apoptosis required concomitant treatment with 5-Azacytidine, an inhibitor of DNA methylation. combination of these chromatin-modifying drugs may be a useful adjuvant in the treatment of rapidly progressive osteosarcoma." epigenetics hsa-mir-431 Osteosarcoma 22957032 "Treatment with 4-phenylbutyrate increased acetylation of histones associated with 14q32 miRNAs, but interestingly, robust restoration of 14q32 miRNA expression, attenuation of cMYC expression, and induction of apoptosis required concomitant treatment with 5-Azacytidine, an inhibitor of DNA methylation. combination of these chromatin-modifying drugs may be a useful adjuvant in the treatment of rapidly progressive osteosarcoma." epigenetics hsa-mir-432 Osteosarcoma 22957032 "Treatment with 4-phenylbutyrate increased acetylation of histones associated with 14q32 miRNAs, but interestingly, robust restoration of 14q32 miRNA expression, attenuation of cMYC expression, and induction of apoptosis required concomitant treatment with 5-Azacytidine, an inhibitor of DNA methylation. combination of these chromatin-modifying drugs may be a useful adjuvant in the treatment of rapidly progressive osteosarcoma." epigenetics hsa-mir-23b Prostate Neoplasms 23074286 miR-23b Represses Proto-oncogene Src Kinase and Functions as Methylation-Silenced Tumor Suppressor with Diagnostic and Prognostic Significance in Prostate Cancer epigenetics hsa-mir-29b-1 Multiple Myeloma 23100393 DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma epigenetics hsa-mir-29b-2 Multiple Myeloma 23100393 DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma epigenetics hsa-mir-200a Breast Neoplasms 23112837 the expression and methylation status of miR-200f could be used as hypothetical biomarkers to assess the occurrence of EMT in breast cancer epigenetics hsa-mir-200b Breast Neoplasms 23112837 the expression and methylation status of miR-200f could be used as hypothetical biomarkers to assess the occurrence of EMT in breast cancer epigenetics hsa-mir-200c Breast Neoplasms 23112837 the expression and methylation status of miR-200f could be used as hypothetical biomarkers to assess the occurrence of EMT in breast cancer epigenetics hsa-mir-149 Colorectal Carcinoma 23115050 Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer epigenetics hsa-mir-137 "Squamous Cell Carcinoma, Oral" 23121285 MicroRNA-137 promoter methylation in oral lichen planus and oral squamous cell carcinoma epigenetics hsa-mir-101-1 Hepatitis B Virus Infection 23124077 miR-101 is down-regulated by the hepatitis B virus x protein and induces aberrant DNA methylation by targeting DNA methyltransferase 3A epigenetics hsa-mir-101-2 Hepatitis B Virus Infection 23124077 miR-101 is down-regulated by the hepatitis B virus x protein and induces aberrant DNA methylation by targeting DNA methyltransferase 3A epigenetics hsa-mir-29b-1 Systemic Lupus Erythematosus 23142053 MicroRNA-29b contributes to DNA hypomethylation of CD4+ T cells in systemic lupus erythematosus by indirectly targeting DNA methyltransferase 1 epigenetics hsa-mir-29b-2 Systemic Lupus Erythematosus 23142053 MicroRNA-29b contributes to DNA hypomethylation of CD4+ T cells in systemic lupus erythematosus by indirectly targeting DNA methyltransferase 1 epigenetics hsa-mir-34b Prostate Neoplasms 23147995 "miRNA-34b Inhibits Prostate Cancer through Demethylation, Active Chromatin Modifications, and AKT Pathways" epigenetics hsa-mir-29b-1 "Leukemia, Myeloid, Acute" 23178755 Increased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: a novel epigenetic-targeting approach in acute myeloid leukemia epigenetics hsa-mir-29b-2 "Leukemia, Myeloid, Acute" 23178755 Increased anti-leukemic activity of decitabine via AR-42-induced upregulation of miR-29b: a novel epigenetic-targeting approach in acute myeloid leukemia epigenetics hsa-mir-29b-1 Ovarian Neoplasms 23179556 Anticancer role of MUC1 aptamer-miR-29b chimera in epithelial ovarian carcinoma cells through regulation of PTEN methylation epigenetics hsa-mir-29b-2 Ovarian Neoplasms 23179556 Anticancer role of MUC1 aptamer-miR-29b chimera in epithelial ovarian carcinoma cells through regulation of PTEN methylation epigenetics hsa-mir-211 Glioma 23183822 "Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis,Chemosensitivity and Radiosensitivity" epigenetics hsa-mir-124 Bladder Neoplasms 23200812 "Among them, miR-137,miR-124-2, miR-124-3, and miR-9-3 were frequently and tumor-specifically methylated in primary cancers" epigenetics hsa-mir-137 Bladder Neoplasms 23200812 "Among them, miR-137,miR-124-2, miR-124-3, and miR-9-3 were frequently and tumor-specifically methylated in primary cancers" epigenetics hsa-mir-9 Bladder Neoplasms 23200812 "Among them, miR-137,miR-124-2, miR-124-3, and miR-9-3 were frequently and tumor-specifically methylated in primary cancers" epigenetics hsa-mir-200a "Carcinoma, Hepatocellular" 23222811 Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma epigenetics hsa-mir-200b "Carcinoma, Hepatocellular" 23222811 Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma epigenetics hsa-mir-200c "Carcinoma, Hepatocellular" 23222811 Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma epigenetics hsa-mir-193a "Leukemia, Myeloid, Acute" 23223432 Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21)acute myeloid leukemia by activating the PTEN/PI3K signal pathway epigenetics hsa-mir-335 "Carcinoma, Hepatocellular" 23229728 Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma epigenetics hsa-mir-31 Prostate Neoplasms 23233736 Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression epigenetics hsa-mir-34a Colon Neoplasms 23243217 Detection of miR-34a Promoter Methylation in Combination with Elevated Expression of c-Met and beta-Catenin Predicts Distant Metastasis of Colon Cancer epigenetics hsa-mir-34a Breast Neoplasms 23292869 Downregulation of miR-34a in breast tumors is not associated with either p53 mutations or promoter hypermethylation while it correlates with metastasis epigenetics hsa-mir-124-1 "Carcinoma, Renal Cell" 23321515 Hsa-mir-124-3 CpG island methylation is associated with advanced tumours and disease recurrence of patients with clear cell renal cell carcinoma epigenetics hsa-mir-124-2 "Carcinoma, Renal Cell" 23321515 Hsa-mir-124-3 CpG island methylation is associated with advanced tumours and disease recurrence of patients with clear cell renal cell carcinoma epigenetics hsa-mir-124-3 "Carcinoma, Renal Cell" 23321515 Hsa-mir-124-3 CpG island methylation is associated with advanced tumours and disease recurrence of patients with clear cell renal cell carcinoma epigenetics hsa-mir-195 Gastric Neoplasms 23333942 MicroRNA-195 and microRNA-378 mediate tumor growth suppression by epigenetical regulation in gastric cancer epigenetics hsa-mir-378a Gastric Neoplasms 23333942 MicroRNA-195 and microRNA-378 mediate tumor growth suppression by epigenetical regulation in gastric cancer epigenetics hsa-mir-124-1 Pancreatic Neoplasms 23334332 Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1 epigenetics hsa-mir-124-2 Pancreatic Neoplasms 23334332 Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1 epigenetics hsa-mir-124-3 Pancreatic Neoplasms 23334332 Methylation-mediated silencing of the miR-124 genes facilitates pancreatic cancer progression and metastasis by targeting Rac1 epigenetics hsa-mir-129-2 "Carcinoma, Hepatocellular" 23402613 Methylation-mediated repression of microRNA 129-2 enhances oncogenic SOX4 expression in HCC epigenetics hsa-mir-200 Breast Neoplasms 23525011 Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem cell-like state epigenetics hsa-mir-146a "Lymphoma, Burkitt" 23528241 "We concluded that similarly to the promoters of protein coding genes, both DNA methylation and histone modifications contribute to the host cell dependent expression of miR-146a." epigenetics hsa-mir-129-1 "Carcinoma, Hepatocellular" 23580407 Frequent DNA methylation of MiR-129-2 and its potential clinical implication in hepatocellular carcinoma epigenetics hsa-mir-129-2 "Carcinoma, Hepatocellular" 23580407 Frequent DNA methylation of MiR-129-2 and its potential clinical implication in hepatocellular carcinoma epigenetics hsa-mir-1286 Human Papilloma Virus Infection 23732000 "We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines." epigenetics hsa-mir-1287 Human Papilloma Virus Infection 23732000 "We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines." epigenetics hsa-mir-1290 Human Papilloma Virus Infection 23732000 "We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines." epigenetics hsa-mir-432 Human Papilloma Virus Infection 23732000 "We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines." epigenetics hsa-mir-641 Human Papilloma Virus Infection 23732000 "We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines." epigenetics hsa-mir-95 Human Papilloma Virus Infection 23732000 "We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines." epigenetics hsa-mir-124a-2 "Carcinoma, Renal Cell" 23755536 "The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue" epigenetics hsa-mir-124a-3 "Carcinoma, Renal Cell" 23755536 "The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue" epigenetics hsa-mir-129-2 "Carcinoma, Renal Cell" 23755536 "The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue" epigenetics hsa-mir-34b "Carcinoma, Renal Cell" 23755536 "The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue" epigenetics hsa-mir-34c "Carcinoma, Renal Cell" 23755536 "The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue" epigenetics hsa-mir-9-1 "Carcinoma, Renal Cell" 23755536 "The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue" epigenetics hsa-mir-9-3 "Carcinoma, Renal Cell" 23755536 "The frequency of methylation of six genes (miR-124a-2, -124a-3, -9-1, -9-3, -34b/c and -129-2) was significantly higher in tumor samples than in samples of histologically normal tissue" epigenetics hsa-mir-29a "Carcinoma, Hepatocellular" 23789939 miR-29a could regulate TGF-¦Â-induced EMT by affecting DNA methylation via the suppression of DNMT. epigenetics hsa-mir-219 Breast Neoplasms 23813567 Aberrant DNA methylation of miR-219 promoter in long-term night shiftworkers. epigenetics hsa-mir-10a Bladder Neoplasms 23867826 "Analyses in human urothelial cells identify methylation of miR-152, miR-200b and miR-10a genes as candidate bladder cancer biomarkers." epigenetics hsa-mir-152 Bladder Neoplasms 23867826 "Analyses in human urothelial cells identify methylation of miR-152, miR-200b and miR-10a genes as candidate bladder cancer biomarkers." epigenetics hsa-mir-200b Bladder Neoplasms 23867826 "Analyses in human urothelial cells identify methylation of miR-152, miR-200b and miR-10a genes as candidate bladder cancer biomarkers." epigenetics hsa-mir-15a "Carcinoma, Lung, Non-Small-Cell" 23867991 Histone deacetylases inhibitor trichostatin A increases the expression of Dleu2/miR-15a/16-1 via HDAC3 in non-small cell lung cancer. epigenetics hsa-mir-16-1 "Carcinoma, Lung, Non-Small-Cell" 23867991 Histone deacetylases inhibitor trichostatin A increases the expression of Dleu2/miR-15a/16-1 via HDAC3 in non-small cell lung cancer. epigenetics hsa-mir-663 "Leukemia, Myeloid, Acute" 23870168 "Expression of miR-663 was significantly lower in pediatric AML cells compared to NBM controls; furthermore, a high frequency of miR-663 promoter hypermethylation was observed in both AML cell lines and pediatric AML samples.Inactivation of miR-663 by promoter hypermethylation could be affected by 5-Aza demethylation. These findings suggest that hypermethylation of the miR-663 promoter may be an early event in the development of pediatric AML." epigenetics hsa-mir-126 Colorectal Carcinoma 23900443 Epigenetic silencing of miR-126 contributes to tumor invasion and angiogenesis in colorectal cancer. epigenetics hsa-mir-29 "Carcinoma, Lung, Non-Small-Cell" 23939044 Suppression of Wnt signaling by the miR-29 family is mediated by demethylation of WIF-1 in non-small-cell lung cancer. epigenetics hsa-mir-34b Gastric Neoplasms 23942619 Our results suggest that methylation of miR-34b/c in the mucosa of the noncancerous gastric body may be a useful biomarker for predicting the risk of metachronous GC. epigenetics hsa-mir-34c Gastric Neoplasms 23942619 Our results suggest that methylation of miR-34b/c in the mucosa of the noncancerous gastric body may be a useful biomarker for predicting the risk of metachronous GC. epigenetics hsa-mir-199a Testicular Neoplasms 23959088 "microRNA-199a-3p, DNMT3A, and aberrant DNA methylation in testicular cancer." epigenetics hsa-mir-126 Systemic Lupus Erythematosus 23981988 The upregulation of miR-126 and its host gene EGFL7 expression in CD4+ T cells from SLE is associated with the hypomethylation of the EGFL7 promoter. epigenetics hsa-mir-328 Breast Neoplasms 23991164 Methylation patterns in the miR-328 5'-flanking region are involved in the inter-individual difference in BCRP levels in human placenta epigenetics hsa-mir-122 "Carcinoma, Hepatocellular" 24085423 The expression of miRNA-122 is regulated by DNA methylation and correlated with apoptosis of liver cancer cells. Methylation regulation of miRNA-122 expression might be involved in the development of hepatocellular carcinoma. epigenetics hsa-mir-29 Neoplasms [unspecific] 24096364 The miR-29 family recurrently regulates active DNA demethylation pathway members TET1 and TDG. epigenetics hsa-mir-203 "Leukemia, Myeloid, Acute, Pediatric" 24103876 miR-203 may not be regulated with methylation mechanism in pediatric acute leukemia. miR- 203 may be a protooncogene involved in the formation of pediatric acute leukemia and ALL. Further analyses indicated that high expression of miR-203 may be associated with poor prognosis of pediatric ALL and acute leukemia. epigenetics hsa-mir-125b Melanoma 24118912 "the reduction in miR-125b expression in pigmented cells was at least partially due to the hypermethylation of the MIR125B-1 promoter, and miR-125b expression was regulated by intracellular cAMP levels." epigenetics hsa-mir-200 Hepatoblastoma 24122292 The strong correlation between expression and DNA methylation suggests a major role for this epigenetic mark in the regulation of the miR-141-200c locus. epigenetics hsa-mir-205 Hepatoblastoma 24122292 The strong correlation between expression and DNA methylation suggests a major role for this epigenetic mark in the regulation of the miR-141-200c locus. epigenetics hsa-mir-214 Lung Fibrosis 24122720 "Stable decreases in miR-124 expression contribute to an epigenetically reprogrammed, highly proliferative, migratory, and inflammatory phenotype of hypertensive pulmonary adventitial fibroblasts. Thus, therapies directed at restoring miR-124 function, including histone deacetylase inhibitors,should be investigated." epigenetics hsa-mir-34b Early-Stage Lung Adenocarcinoma 24130071 Epigenetic inactivation of microRNA-34b/c predicts poor disease-free survival in early-stage lung adenocarcinoma. epigenetics hsa-mir-34c Early-Stage Lung Adenocarcinoma 24130071 Epigenetic inactivation of microRNA-34b/c predicts poor disease-free survival in early-stage lung adenocarcinoma. epigenetics hsa-mir-29b Liver Fibrosis 24138392 Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation--a novel mechanism suppressing liver fibrosis. epigenetics hsa-mir-34b Pleural Mesothelioma 24168922 "Our digital MSP assay can quantify miR-34b/c methylation in serum-circulating DNA. The degree of miR-34b/c methylation in serum-circulating DNA is associated with MPM, suggesting that this approach might be useful for the establishment of a new detection system for MPM." epigenetics hsa-mir-34c Pleural Mesothelioma 24168922 "Our digital MSP assay can quantify miR-34b/c methylation in serum-circulating DNA. The degree of miR-34b/c methylation in serum-circulating DNA is associated with MPM, suggesting that this approach might be useful for the establishment of a new detection system for MPM." epigenetics hsa-mir-375 Prostate Neoplasms 24173286 Androgen receptor is negatively correlated with the methylation-mediated transcriptional repression of miR-375 in human prostate cancer cells. epigenetics hsa-mir-143 Breast Neoplasms 24218337 MicroRNA-143 is downregulated in breast cancer and regulates DNA methyltransferases 3A in breast cancer cells. epigenetics hsa-mir-124a Rheumatoid Arthritis 24223605 "The methylation status of miR-124a seen in this study concurs with that reported in tumor cells, indicating epigenetic dysregulation constituents, a mechanism in the development of rheumatoid arthritis." epigenetics hsa-mir-203 Rhabdomyosarcoma 24247238 "miR-203, a tumor suppressor frequently down-regulated by promoter hypermethylation in rhabdomyosarcoma." epigenetics hsa-mir-148b Breast Neoplasms 24257477 "Our data provide novel evidence of the mechanisms behind miRNA dysregulation in breast cancer. The study contributes to the understanding of how methylation and copy number alterations influence miRNA expression, emphasizing miRNA functionality through redundant encoding, and suggests novel miRNAs important in breast cancer." epigenetics hsa-mir-151a Breast Neoplasms 24257477 "Our data provide novel evidence of the mechanisms behind miRNA dysregulation in breast cancer. The study contributes to the understanding of how methylation and copy number alterations influence miRNA expression, emphasizing miRNA functionality through redundant encoding, and suggests novel miRNAs important in breast cancer." epigenetics hsa-mir-21 Breast Neoplasms 24257477 "Our data provide novel evidence of the mechanisms behind miRNA dysregulation in breast cancer. The study contributes to the understanding of how methylation and copy number alterations influence miRNA expression, emphasizing miRNA functionality through redundant encoding, and suggests novel miRNAs important in breast cancer." epigenetics hsa-mir-29c Breast Neoplasms 24297604 Dysregulation of microRNA expression drives aberrant DNA hypermethylation in basal-like breast cancer. epigenetics hsa-mir-199a Chronic Obstructive Pulmonary Disease 24299514 "miR-199a-5p is a key regulator of the unfolded protein response in AAT-deficient monocytes, and epigenetic silencing of its expression regulates this process in chronic obstructive pulmonary disease." epigenetics hsa-mir-124a Melanoma 24303550 Epigenetic regulation of melanoma tumor suppressor miRNA-124a. epigenetics hsa-mir-128a "Leukemia, T-Cell" 24316133 Epigenetic regulation of microRNA-128a expression contributes to the apoptosis-resistance of human T-cell leukaemia jurkat cells by modulating expression of fas-associated protein with death domain (FADD). epigenetics hsa-mir-223 "Carcinoma, Hepatocellular" 24333181 Downregulation of miR-223 in HCC is associated with the epigenetic regulation by highly expressed sulfatide and involved in tumor metastasis. epigenetics hsa-mir-205 Hepatitis B Virus Infection 24339740 Hepatitis B virus X protein inhibits tumor suppressor miR-205 through inducing hypermethylation of miR-205 promoter to enhance carcinogenesis. epigenetics hsa-mir-9 Medulloblastoma 24346283 microRNA-9 is a methylation-silenced tumour suppressor that could be a potential candidate predictive marker for poor prognosis of medulloblastoma. epigenetics hsa-mir-22 Ewing Sarcoma 24362521 The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma. epigenetics hsa-let-7c Cardiomyopathy 24365598 Cardiomyogenesis is controlled by the miR-99a/let-7c cluster and epigenetic modifications. epigenetics hsa-mir-99a Cardiomyopathy 24365598 Cardiomyogenesis is controlled by the miR-99a/let-7c cluster and epigenetic modifications. epigenetics hsa-mir-375 "Diabetes Mellitus, Type 2" 24366165 Expression and DNA methylation status of microRNA-375 in patients with type 2 diabetes mellitus. epigenetics hsa-mir-9 "Leukemia, Lymphocytic, Chronic, B-Cell" 24373626 "Of the miR-9 family, miR-9-3 is a tumor suppressor miRNA relatively frequently methylated, and hence silenced in CLL; whereas miR-9-1 methylation is rare in CLL. The role of miR-9-3 methylation in the constitutive activation of NF¦ÊB signaling pathway in CLL warrants further study." epigenetics hsa-mir-124a-1 Breast Neoplasms 24375250 "Methylation of miR-124a-1, miR-124a-2, and miR-124a-3 genes correlates with aggressive and advanced breast cancer disease." epigenetics hsa-mir-124a-2 Breast Neoplasms 24375250 "Methylation of miR-124a-1, miR-124a-2, and miR-124a-3 genes correlates with aggressive and advanced breast cancer disease." epigenetics hsa-mir-124a-3 Breast Neoplasms 24375250 "Methylation of miR-124a-1, miR-124a-2, and miR-124a-3 genes correlates with aggressive and advanced breast cancer disease." epigenetics hsa-mir-124 Pulmonary Hypertension 24385500 Deacetylation of MicroRNA-124 in fibroblasts: role in pulmonary hypertension. epigenetics hsa-mir-297 Squamous Cell Carcinoma 24394434 Phospho-¦¤Np63¦Á/microRNA network modulates epigenetic regulatory enzymes in squamous cell carcinomas. epigenetics hsa-mir-485 Squamous Cell Carcinoma 24394434 Phospho-¦¤Np63¦Á/microRNA network modulates epigenetic regulatory enzymes in squamous cell carcinomas. epigenetics hsa-mir-92b Squamous Cell Carcinoma 24394434 Phospho-¦¤Np63¦Á/microRNA network modulates epigenetic regulatory enzymes in squamous cell carcinomas. epigenetics hsa-mir-34a Bladder Neoplasms 24423412 "Cisplatin-based chemotherapy induced demethylation of miR-34a promoter and increased miR-34a expression, which in turn sensitized MIBC cells to cisplatin and decreased the tumorigenicity and proliferation of cancer cells that by reducing the production of CD44." epigenetics hsa-let-7a-3 Neoplasms [unspecific] 24423609 Reduction of let-7a3/let-7b miRNA may be one of mechanisms leading to overexpression of HMGA2 in AT/RT tissues. epigenetics hsa-mir-1258 Lung Neoplasms 24450160 Novel miRNA genes methylated in lung tumors. epigenetics hsa-mir-137 Lung Neoplasms 24450160 Novel miRNA genes methylated in lung tumors. epigenetics hsa-mir-375 Lung Neoplasms 24450160 Novel miRNA genes methylated in lung tumors. epigenetics hsa-mir-21 Pancreatic Neoplasms 24460329 MiR-21 upregulation induced by histone acetylation in the promoter zone is associated with chemoresistance to gemcitabine and enhanced malignant potential in pancreatic cancer cells. epigenetics hsa-mir-10b Gastric Neoplasms 24481854 "Taken together, these findings suggest that miR-10b may function as a novel tumor suppressor and is partially silenced by DNA hypermethylation in GC." epigenetics hsa-mir-1260b Prostate Neoplasms 24504368 Our data suggest that genistein exerts its anti-tumour effect via downregulation of miR-1260b that targeted sRRP1 and Smad4 genes in prostate cancer cells. The expression of sFRP1 and Smad4 was also modulated by genistein via DNA methylation or histone modifications in PC cell lines. epigenetics hsa-mir-203 "Carcinoma, Endometrial" 24530564 "Hypermethylation of miR-203 is a frequent event in endometrial carcinomas and is strongly associated with microsatellite instability and MLH1 methylation status. Thus, miR-203 methylation level might represent a marker for patients with endometrioid and clear endometrial sub-cancers." epigenetics hsa-mir-34a "Leukemia, Lymphocytic, Chronic, B-Cell" 24559316 "Taken together, miR-34b/c is a tumor suppressor miRNA frequently methylated, and hence silenced in CLL. Together with DAPK1 methylation, miR-34b/c methylation is implicated in the disruption of the TP53-centered tumor suppressor network. Moreover, the association of miRNA methylation warrants further study." epigenetics hsa-mir-34b "Leukemia, Lymphocytic, Chronic, B-Cell" 24559316 "Taken together, miR-34b/c is a tumor suppressor miRNA frequently methylated, and hence silenced in CLL. Together with DAPK1 methylation, miR-34b/c methylation is implicated in the disruption of the TP53-centered tumor suppressor network. Moreover, the association of miRNA methylation warrants further study." epigenetics hsa-mir-34c "Leukemia, Lymphocytic, Chronic, B-Cell" 24559316 "Taken together, miR-34b/c is a tumor suppressor miRNA frequently methylated, and hence silenced in CLL. Together with DAPK1 methylation, miR-34b/c methylation is implicated in the disruption of the TP53-centered tumor suppressor network. Moreover, the association of miRNA methylation warrants further study." epigenetics hsa-mir-375 "Carcinoma, Breast" 24571711 "Epigenetic silencing of miR-375 causes the upregulation of IGF1R,which at least partially underlies trastuzumab resistance of breast cancer cells.Our study has implications for miR-375 as a potential target in combination with trastuzumab for treating HER2-positive breast cancers." epigenetics hsa-mir-429 "Carcinoma, Hepatocellular" 24572141 "Epigenetic modification of miR-429 can manipulate liver T-ICs by targeting the RBBP4/E2F1/OCT4 axis. This miRNA might be targeted to inactivate T-ICs, thus providing a novel strategy for HCC prevention and treatment." epigenetics hsa-mir-199b Ovarian Neoplasms 24659709 Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer. epigenetics hsa-mir-127 Lung Neoplasms 24665010 Epigenetic analysis of microRNA genes in tumors from surgically resected lung cancer patients and association with survival. epigenetics hsa-mir-491 Liver Neoplasms 24680928 Arsenic trioxide attenuates the invasion potential of human liver cancer cells through the demethylation-activated microRNA-491. epigenetics hsa-mir-34 "Leukemia, Lymphocytic, Chronic, B-Cell" 24686393 microRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemia. epigenetics hsa-mir-34b "Leukemia, Lymphocytic, Chronic, B-Cell" 24686393 microRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemia. epigenetics hsa-mir-34c "Leukemia, Lymphocytic, Chronic, B-Cell" 24686393 microRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemia. epigenetics hsa-let-7a-3 "Leukemia, Myeloid, Acute" 24703161 "MicroRNA let-7a-3 gene methylation is associated with karyotyping, CEBPA promoter methylation, and survival in acute myeloid leukemia." epigenetics hsa-mir-34b "Carcinoma, Hepatocellular" 24704024 Methylation-associated silencing of microRNA-34b in hepatocellular carcinoma cancer. epigenetics hsa-mir-148a "Carcinoma, Hepatocellular" 24714841 MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in hepatocellular carcinogenesis. epigenetics hsa-mir-200c Breast Neoplasms 24729530 Induction of the mesenchymal to epithelial transition by demethylation- activated microRNA-200c is involved in the anti-migration/invasion effects of arsenic trioxide on human breast cancer cells. epigenetics hsa-mir-224 Prostate Neoplasms 24737792 "The GABRE-miR-452-miR-224 locus is downregulated and hypermethylated in prostate cancer and is a new promising epigenetic candidate biomarker for prostate cancer diagnosis and prognosis. Tumor-suppressive functions of the intronic miR-224 and miR-452 were demonstrated in two prostate cancer cell lines,suggesting that epigenetic silencing of GABRE/miR-452/miR-224 may be selected for in prostate cancer." epigenetics hsa-mir-452 Prostate Neoplasms 24737792 "The GABRE-miR-452-miR-224 locus is downregulated and hypermethylated in prostate cancer and is a new promising epigenetic candidate biomarker for prostate cancer diagnosis and prognosis. Tumor-suppressive functions of the intronic miR-224 and miR-452 were demonstrated in two prostate cancer cell lines,suggesting that epigenetic silencing of GABRE/miR-452/miR-224 may be selected for in prostate cancer." epigenetics hsa-mir-302 "Carcinoma, Hepatocellular" 24740829 "miR-302-mediated iPSC technology reprogrammed HCC cells and improved drug sensitivity through AOF2 down-regulation, which caused H3K4 methylation and c-Myc repression." epigenetics hsa-mir-375 "Diabetes Mellitus, Type 2" 24741571 Ethnic differences in microRNA-375 expression level and DNA methylation status in type 2 diabetes of Han and Kazak populations. epigenetics hsa-mir-31 "Adenocarcinoma, Colon" 24752710 "MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions." epigenetics hsa-mir-615 "Adenocarcinoma, Pancreatic Ductal" 24769899 miR-615-5p is epigenetically inactivated and functions as a tumor suppressor in pancreatic ductal adenocarcinoma. epigenetics hsa-mir-449a Gastric Neoplasms 24810364 Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a. epigenetics hsa-mir-99a Gastric Neoplasms 24810364 Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a. epigenetics hsa-mir-214 Rhabdomyosarcoma 24811402 MiR-214 and N-ras regulatory loop suppresses rhabdomyosarcoma cell growth and xenograft tumorigenesis. epigenetics hsa-mir-34a "Leukemia, Promyelocytic, Acute" 24811488 "Epigenetic inactivation of DAPK1, p14ARF, mir-34a and -34b/c in acute promyelocytic leukaemia." epigenetics hsa-mir-34b "Leukemia, Promyelocytic, Acute" 24811488 "Epigenetic inactivation of DAPK1, p14ARF, mir-34a and -34b/c in acute promyelocytic leukaemia." epigenetics hsa-mir-34c "Leukemia, Promyelocytic, Acute" 24811488 "Epigenetic inactivation of DAPK1, p14ARF, mir-34a and -34b/c in acute promyelocytic leukaemia." epigenetics hsa-mir-126 Myeloma 24875904 "TNF¦Á in the marrow microenvironment led to RANKL demethylation and re-expression in myeloma cells through DNMT1 repression and upregulation of miR-126-3p and miR-140, both known to repress DNMT1 translation." epigenetics hsa-mir-140 Myeloma 24875904 "TNF¦Á in the marrow microenvironment led to RANKL demethylation and re-expression in myeloma cells through DNMT1 repression and upregulation of miR-126-3p and miR-140, both known to repress DNMT1 translation." epigenetics hsa-mir-146a Prostate Neoplasms 24885368 "Up-regulating miR-146a expression via the hypomethylation of the miR-146a promoter by 5-Aza-CdR was correlated with delayed progression of castration-resistant prostate cancers. Moreover, site-specific DNA methylation may play an important role in miR-146a expression in androgen-dependent prostate cancer progression to androgen-independent prostate cancer and therefore provides a potentially useful biomarker for assessing drug efficacy in prostate cancer." epigenetics hsa-mir-15a "Leukemia, Myeloid, Acute" 24885794 "The DLEU2 locus and embedded miRNA cluster miR-15a/16-1 is commonly deleted in adult cancers and shown to induce leukaemogenesis, however in paediatric AML we found the region to be transcriptionally repressed. In combination, our data highlights the utility of interrogating DNA methylation and microRNA in combination with underlying genetic status to provide novel insights into AML biology." epigenetics hsa-mir-16-1 "Leukemia, Myeloid, Acute" 24885794 "The DLEU2 locus and embedded miRNA cluster miR-15a/16-1 is commonly deleted in adult cancers and shown to induce leukaemogenesis, however in paediatric AML we found the region to be transcriptionally repressed. In combination, our data highlights the utility of interrogating DNA methylation and microRNA in combination with underlying genetic status to provide novel insights into AML biology." epigenetics hsa-mir-30b Gastric Neoplasms 24913034 Decreased miR-30b-5p expression by DNMT1 methylation regulation involved in gastric cancer metastasis. epigenetics hsa-mir-200 Breast Neoplasms 24918286 SUMOylation of FOXM1B alters its transcriptional activity on regulation of MiR-200 family and JNK1 in MCF7 human breast cancer cells. epigenetics hsa-mir-219 Chronic Inflammatory Pain 25031391 methylation-mediated epigenetic modification of spinal miR-219 expression regulates chronic inflammatory pain by targeting CaMKII¦Ã. epigenetics hsa-mir-105 Neoplasms [unspecific] 25089631 A novel cancer-germline transcript carrying pro-metastatic miR-105 and TET-targeting miR-767 induced by DNA hypomethylation in tumors. epigenetics hsa-mir-767 Neoplasms [unspecific] 25089631 A novel cancer-germline transcript carrying pro-metastatic miR-105 and TET-targeting miR-767 induced by DNA hypomethylation in tumors. epigenetics hsa-mir-145 Chondrosarcoma 25145279 The epigenetic regulation of SOX9 by miR-145 in human chondrosarcoma. epigenetics hsa-mir-149 Breast Neoplasms 25156775 Methylation-regulated miR-149 modulates chemoresistance by targeting GlcNAc N-deacetylase/N-sulfotransferase-1 in human breast cancer. epigenetics hsa-mir-320a Breast Neoplasms 25159093 A methylation-based regulatory network for microRNA 320a in chemoresistant breast cancer. epigenetics hsa-mir-200 Neoplasms [unspecific] 25178837 Zeb1 and Snail1 engage miR-200f transcriptional and epigenetic regulation during EMT. epigenetics hsa-mir-210 Helicobacter pylori Infection 25187177 Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection. epigenetics hsa-mir-193a Bladder Neoplasms 25188512 The DNA methylation-regulated miR-193a-3p dictates the multi-chemoresistance of bladder cancer via repression of SRSF2/PLAU/HIC2 expression. epigenetics hsa-mir-101 Lung Neoplasms 25210796 Restoration of miR-101 suppresses lung tumorigenesis through inhibition of DNMT3a-dependent DNA methylation. epigenetics hsa-mir-155 "Lymphoma, Non-Hodgkin" 25211095 Methylation of miR-155-3p in mantle cell lymphoma and other non-Hodgkin's lymphomas. epigenetics hsa-mir-106b Polycystic Ovarian Syndrome 25243570 "Our data suggest that the expression of MCM7 and miR-93/25 is PCOSand IR related, whereas that of miR-106b is related to IR only. In 3T3-L1 adipocytes, neither hyperglycemia nor hyperinsulinemia altered the expression of miR-93 or miR-25, although increasing glucose levels down-regulated MCM7 and paradoxically increased that of miR-106b expression. The expression of the miR-25/93/106b family may be regulated through mechanisms distinct from its host gene, MCM7. Finally, our studies suggest potential epigenetic mechanisms for both IR and PCOS." epigenetics hsa-mir-25 Polycystic Ovarian Syndrome 25243570 "Our data suggest that the expression of MCM7 and miR-93/25 is PCOSand IR related, whereas that of miR-106b is related to IR only. In 3T3-L1 adipocytes, neither hyperglycemia nor hyperinsulinemia altered the expression of miR-93 or miR-25, although increasing glucose levels down-regulated MCM7 and paradoxically increased that of miR-106b expression. The expression of the miR-25/93/106b family may be regulated through mechanisms distinct from its host gene, MCM7. Finally, our studies suggest potential epigenetic mechanisms for both IR and PCOS." epigenetics hsa-mir-93 Polycystic Ovarian Syndrome 25243570 "Our data suggest that the expression of MCM7 and miR-93/25 is PCOSand IR related, whereas that of miR-106b is related to IR only. In 3T3-L1 adipocytes, neither hyperglycemia nor hyperinsulinemia altered the expression of miR-93 or miR-25, although increasing glucose levels down-regulated MCM7 and paradoxically increased that of miR-106b expression. The expression of the miR-25/93/106b family may be regulated through mechanisms distinct from its host gene, MCM7. Finally, our studies suggest potential epigenetic mechanisms for both IR and PCOS." epigenetics hsa-mir-9 Gastric Neoplasms 25270964 Epigenetic silencing of miRNA-9 is correlated with promoter-proximal CpG island hypermethylation in gastric cancer in vitro and in vivo. epigenetics hsa-mir-148a "Carcinoma, Nasopharyngeal" 25277193 Silencing of miRNA-148a by hypermethylation activates the integrin-mediated signaling pathway in nasopharyngeal carcinoma. epigenetics hsa-mir-10b Squamous Cell Carcinoma 25312779 Reduction of TIP30 in esophageal squamous cell carcinoma cells involves promoter methylation and microRNA-10b. epigenetics hsa-mir-24 "Carcinoma, Nasopharyngeal" 25319395 Involvement of microRNA-24 and DNA methylation in resistance of nasopharyngeal carcinoma to ionizing radiation. epigenetics hsa-mir-129 Gastric Neoplasms 25344911 Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters. epigenetics hsa-mir-214 "Leukemia, Lymphocytic, Chronic, B-Cell" 25361012 "miR-26a and miR-214 down-regulate expression of the PTEN gene in chronic lymphocytic leukemia, but not PTEN mutation or promoter methylation." epigenetics hsa-mir-26a "Leukemia, Lymphocytic, Chronic, B-Cell" 25361012 "miR-26a and miR-214 down-regulate expression of the PTEN gene in chronic lymphocytic leukemia, but not PTEN mutation or promoter methylation." epigenetics hsa-mir-34b Breast Neoplasms 25398683 long-term shiftwork may increase the risk of breast cancer via methylation-based suppression of miR-34b and a consequent reduction in immunomediated anti-tumor capacity and support our previous findings that LAN may induce epigenetic alteration of cancer-relevant microRNAs. epigenetics hsa-mir-142 "Lymphoma, T-Cell" 25405321 These results reveal a subgroup-specific epigenetically regulated microRNA signatures for MFt and CD30+ cALCL patients. epigenetics hsa-mir-146a "Lymphoma, T-Cell" 25405321 These results reveal a subgroup-specific epigenetically regulated microRNA signatures for MFt and CD30+ cALCL patients. epigenetics hsa-mir-155 "Lymphoma, T-Cell" 25405321 These results reveal a subgroup-specific epigenetically regulated microRNA signatures for MFt and CD30+ cALCL patients. epigenetics hsa-mir-181b "Lymphoma, T-Cell" 25405321 These results reveal a subgroup-specific epigenetically regulated microRNA signatures for MFt and CD30+ cALCL patients. epigenetics hsa-mir-21 "Lymphoma, T-Cell" 25405321 These results reveal a subgroup-specific epigenetically regulated microRNA signatures for MFt and CD30+ cALCL patients. epigenetics hsa-mir-720 "Leukemia, Myeloid, Acute" 25417880 "The expression of miR-720 in AML patients reduced significantly, and DNA methylation-mediated epigenetic silencing of miR-720 contributed to maintain the malignant characteristics of AML." epigenetics hsa-mir-34a Colorectal Carcinoma 25422210 "miRNA-34a-5p may play a role as a tumor suppressor gene in colorectal cancer, with involvement of DNA methylation." epigenetics hsa-mir-106b "Carcinoma, Hepatocellular" 25424171 "DNA methylation plays an important and complex role in the regulation of miRNA expression in HCC, which may provide insights into the pathogenesis of HCC and thus may be used for diagnosis and intervention." epigenetics hsa-mir-148a "Carcinoma, Hepatocellular" 25424171 "DNA methylation plays an important and complex role in the regulation of miRNA expression in HCC, which may provide insights into the pathogenesis of HCC and thus may be used for diagnosis and intervention." epigenetics hsa-mir-195 "Carcinoma, Hepatocellular" 25424171 "DNA methylation plays an important and complex role in the regulation of miRNA expression in HCC, which may provide insights into the pathogenesis of HCC and thus may be used for diagnosis and intervention." epigenetics hsa-mir-23a "Carcinoma, Hepatocellular" 25424171 "DNA methylation plays an important and complex role in the regulation of miRNA expression in HCC, which may provide insights into the pathogenesis of HCC and thus may be used for diagnosis and intervention." epigenetics hsa-mir-25 "Carcinoma, Hepatocellular" 25424171 "DNA methylation plays an important and complex role in the regulation of miRNA expression in HCC, which may provide insights into the pathogenesis of HCC and thus may be used for diagnosis and intervention." epigenetics hsa-mir-27a "Carcinoma, Hepatocellular" 25424171 "DNA methylation plays an important and complex role in the regulation of miRNA expression in HCC, which may provide insights into the pathogenesis of HCC and thus may be used for diagnosis and intervention." epigenetics hsa-mir-375 "Carcinoma, Hepatocellular" 25424171 "DNA methylation plays an important and complex role in the regulation of miRNA expression in HCC, which may provide insights into the pathogenesis of HCC and thus may be used for diagnosis and intervention." epigenetics hsa-mir-378 "Carcinoma, Hepatocellular" 25424171 "DNA methylation plays an important and complex role in the regulation of miRNA expression in HCC, which may provide insights into the pathogenesis of HCC and thus may be used for diagnosis and intervention." epigenetics hsa-mir-497 "Carcinoma, Hepatocellular" 25424171 "DNA methylation plays an important and complex role in the regulation of miRNA expression in HCC, which may provide insights into the pathogenesis of HCC and thus may be used for diagnosis and intervention." epigenetics hsa-mir-93 "Carcinoma, Hepatocellular" 25424171 "DNA methylation plays an important and complex role in the regulation of miRNA expression in HCC, which may provide insights into the pathogenesis of HCC and thus may be used for diagnosis and intervention." epigenetics hsa-mir-155 Multiple Myeloma 25497370 "DNA methylation contributes to miR-155 expression in myeloma cells. Interestingly, the survival data showed an association between miR-155 expression and outcome of MM." epigenetics hsa-mir-141 Gastric Neoplasms 25502084 "sion of miR-200c/141 induced by TGF-¦Â in SGC-7901 cells. Our study revealed that miR-200c/141 was downregulated by CpG island methylation and TGF-¦Â signaling, which decreased ZEB1/2 expression and increased E-cadherin expression to inhibit migration and invasion of gastric cancer cells and provides powerful evidence for the application of decitabine in gastric cancer treatment." epigenetics hsa-mir-155 "Carcinoma, Colon" 25502084 "miR-200c/141 was downregulated by CpG island methylation and TGF-¦Â signaling, which decreased ZEB1/2 expression and increased E-cadherin expression to inhibit migration and invasion of gastric cancer cells and provides powerful evidence for the application of decitabine in gastric cancer treatment." epigenetics hsa-mir-200 Gastric Neoplasms 25502084 "sion of miR-200c/141 induced by TGF-¦Â in SGC-7901 cells. Our study revealed that miR-200c/141 was downregulated by CpG island methylation and TGF-¦Â signaling, which decreased ZEB1/2 expression and increased E-cadherin expression to inhibit migration and invasion of gastric cancer cells and provides powerful evidence for the application of decitabine in gastric cancer treatment." epigenetics hsa-mir-490 "Carcinoma, Gastric" 25503559 "hypermethylation-mediated silencing of miR-490-3p reactivates SMARCD1 to confer malignant phenotypes, mechanistically linking H. pylori, chromatin remodeling, and gastric carcinogenesis." epigenetics hsa-mir-137 Neuroblastoma 25505154 "an epigenetic mechanism involving miR-137-mediated EZH2 repression in RSV-induced apoptosis and tumor suppression of neuroblastoma, which would provide a key potential therapeutic target in neuroblastoma treatment." epigenetics hsa-mir-21 "Leukemia, Myeloid, Chronic" 25575817 RBP2 epigenetically downregulated miR-21 in blast transformation of CML. epigenetics hsa-mir-34b Leukemia 25582471 "The hypermethylation of promoter leads to decrease in the expression levels of miR-34b in leukemia cell lines, which attenuate mechanism of proliferative inhibition may be one of the reasons of occurrence or development of childhood leukemia." epigenetics hsa-mir-328 Osteosarcoma 25605016 the role of RESV-induced molecular and epigenetic regulation in suppressing tumor metastasis. epigenetics hsa-mir-34b Wilms Tumor 25625843 Epigenetic analysis of sporadic and Lynch-associated ovarian cancers reveals histology-specific patterns of DNA methylation. epigenetics hsa-mir-142 Systemic Lupus Erythematosus 25661834 "Data from this study suggest that MPA activates miR-142 and miR-146a expression through histone modification at the promoter region, which may partially explain the pharmacological mechanisms of MPA for SLE." epigenetics hsa-mir-146a Systemic Lupus Erythematosus 25661834 "Data from this study suggest that MPA activates miR-142 and miR-146a expression through histone modification at the promoter region, which may partially explain the pharmacological mechanisms of MPA for SLE." epigenetics hsa-mir-375 Myeloproliferative Neoplasms 25666256 Epigenetic deregulated miR-375 contributes to the constitutive activation of JAK2/STAT signaling in myeloproliferative neoplasm. epigenetics hsa-mir-484 Colorectal Carcinoma 25727216 Methylation-induced loss of miR-484 in microsatellite-unstable colorectal cancer promotes both viability and IL-8 production via CD137L. epigenetics hsa-mir-125b-2 Prostate Neoplasms 25728837 Our work underlined the importance of histone demethylation and DNA oxidation/repairing machinery in androgen-dependent transcription. The present finds have implications for research into new druggable targets for prostate cancer relying on the cascade of AR activity regulation. epigenetics hsa-mir-133b Prostate Neoplasms 25728837 Our work underlined the importance of histone demethylation and DNA oxidation/repairing machinery in androgen-dependent transcription. The present finds have implications for research into new druggable targets for prostate cancer relying on the cascade of AR activity regulation. epigenetics hsa-mir-145 Prostate Neoplasms 25749421 A feedback regulation between miR-145 and DNA methyltransferase 3b in prostate cancer cell and their responses to irradiation. epigenetics hsa-mir-129-2 Glioma 25772485 MiR-129-2 functions as a tumor suppressor in glioma cells by targeting HMGB1 and is down-regulated by DNA methylation. epigenetics hsa-mir-34b Soft Tissue Sarcoma 25773680 Hypermethylation of potential tumor suppressor miR-34b/c is correlated with late clinical stage in patients with soft tissue sarcomas. epigenetics hsa-mir-34c Soft Tissue Sarcoma 25773680 Hypermethylation of potential tumor suppressor miR-34b/c is correlated with late clinical stage in patients with soft tissue sarcomas. epigenetics hsa-mir-101 Glioma 25829251 MiR-101 reverses the hypomethylation of the LMO3 promoter in glioma cells. epigenetics hsa-mir-9-1 Multiple Myeloma 25855800 "Hypermethylation of miR-9-3 and miR-9-1 is tumour-specific in MM,leading to reversible miRNA silencing. Frequent methylation of miR-9-3 and miR-9-1 in cell lines, but not in primary samples, may be acquired during in vitro culture, and indicates an unimportant role of miR-9 methylation in myelomagenesis." epigenetics hsa-mir-9-3 Multiple Myeloma 25855800 "Hypermethylation of miR-9-3 and miR-9-1 is tumour-specific in MM,leading to reversible miRNA silencing. Frequent methylation of miR-9-3 and miR-9-1 in cell lines, but not in primary samples, may be acquired during in vitro culture, and indicates an unimportant role of miR-9 methylation in myelomagenesis." epigenetics hsa-mir-34a Gastric Neoplasms 25860861 Sirt7 promotes gastric cancer growth and inhibits apoptosis by epigenetically inhibiting miR-34a. epigenetics hsa-mir-124 Prostate Neoplasms 25860954 Regulation and methylation of tumor suppressor miR-124 by androgen receptor in prostate cancer cells. epigenetics hsa-mir-29b Gastric Neoplasms 25874772 "Deregulation between miR-29b/c and DNMT3A is associated with epigenetic silencing of the CDH1 gene, affecting cell migration and invasion in gastric cancer." epigenetics hsa-mir-29c Gastric Neoplasms 25874772 "Deregulation between miR-29b/c and DNMT3A is associated with epigenetic silencing of the CDH1 gene, affecting cell migration and invasion in gastric cancer." epigenetics hsa-mir-24-2 Neoplasms [unspecific] 25943634 The conclusion drawn of hsa-miR-24-2 targeting the genes of cell survival correlated with the methylation profile and resultant transcription factor binding site gain or loss in support of absence of cell survival. epigenetics hsa-mir-182 Lung Neoplasms 25975295 DNA methylation occurs in the miR-182 promoter region in lung cancer cell lines. This methylation can regulate the expression level of miR-182.Further study must be conducted to explore the function of miR-182 promoter methylation in lung cancer occurrence and development. epigenetics hsa-mir-34b Neoplasms [unspecific] 25979762 "although results obtained by the different DNA methylation analysis techniques are largely comparable, an appropriate correction may be necessary for stringent comparison." epigenetics hsa-mir-34c Neoplasms [unspecific] 25979762 "although results obtained by the different DNA methylation analysis techniques are largely comparable, an appropriate correction may be necessary for stringent comparison." epigenetics hsa-mir-148a Breast Neoplasms 25980823 Glabridin inhibits cancer stem cell-like properties of human breast cancer cells:An epigenetic regulation of miR-148a/SMAd2 signaling. epigenetics hsa-mir-137 Neoplasms [unspecific] 26066330 We also found that miR-137 and its host gene are epigenetically silenced in human cancer specimens and cell lines.These results support the development and testing of microRNA-based therapies (in particular based on restoring miR-137 levels) for targeting the oncogenic family of p160 SRCs in cancer. epigenetics hsa-mir-129-2 Lung Neoplasms 26081366 Epigenetic regulation of miR-129-2 and its effects on the proliferation and invasion in lung cancer cells. epigenetics hsa-mir-302c Chondrosarcoma 26094604 Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1. epigenetics hsa-mir-10a Atherosclerosis 26148682 "Methylation-specific PCR (MSP) confirmed differential CpG methylation of HOXA genes, the ER stress gene ATF4, inflammatory regulator microRNA-10a and ARHGAP25 that encodes a negative regulator of Rho GTPases involved in cytoskeleton remodeling." epigenetics hsa-mir-137 Glioblastoma 26187071 Direct transfection of miR-137 mimics is more effective than DNA demethylation of miR-137 promoter to augment anti-tumor mechanisms of delphinidin in human glioblastoma U87MG and LN18 cells. epigenetics hsa-mir-203 Melanoma 26225581 DNA methylation contributes toward silencing of antioncogenic microRNA-203 in human and canine melanoma cells. epigenetics hsa-mir-210 Cardiovascular Diseases [unspecific] 26254226 Oxidized low-density lipoprotein is a common risk factor for cardiovascular diseases and gastroenterological cancers via epigenomical regulation of microRNA-210. epigenetics hsa-mir-145 "Squamous Cell Carcinoma, Esophageal" 26254350 Suppressor microRNA-145 Is Epigenetically Regulated by Promoter Hypermethylation in Esophageal Squamous Cell Carcinoma. epigenetics hsa-mir-139 "Carcinoma, Lung, Non-Small-Cell" 26256448 Histone methylation-mediated silencing of miR-139 enhances invasion of non-small-cell lung cancer. epigenetics hsa-let-7 Neoplasms [unspecific] 26303212 Impact of Histone Deacetylase Inhibitors on microRNA Expression and Cancer Therapy: A Review. epigenetics hsa-mir-106a Neoplasms [unspecific] 26303212 Impact of Histone Deacetylase Inhibitors on microRNA Expression and Cancer Therapy: A Review. epigenetics hsa-mir-106b Neoplasms [unspecific] 26303212 Impact of Histone Deacetylase Inhibitors on microRNA Expression and Cancer Therapy: A Review. epigenetics hsa-mir-15a Neoplasms [unspecific] 26303212 Impact of Histone Deacetylase Inhibitors on microRNA Expression and Cancer Therapy: A Review. epigenetics hsa-mir-16 Neoplasms [unspecific] 26303212 Impact of Histone Deacetylase Inhibitors on microRNA Expression and Cancer Therapy: A Review. epigenetics hsa-mir-17 Neoplasms [unspecific] 26303212 Impact of Histone Deacetylase Inhibitors on microRNA Expression and Cancer Therapy: A Review. epigenetics hsa-mir-19b Neoplasms [unspecific] 26303212 Impact of Histone Deacetylase Inhibitors on microRNA Expression and Cancer Therapy: A Review. epigenetics hsa-mir-148 Hematologic Neoplasms 26314468 "This article summarizes the expression of miR-148/152 family in hematological malignancies, aiming at expounding the signicance of relationship between DNA methylation modification and microRNA." epigenetics hsa-mir-152 Hematologic Neoplasms 26314468 "This article summarizes the expression of miR-148/152 family in hematological malignancies, aiming at expounding the signicance of relationship between DNA methylation modification and microRNA." epigenetics hsa-mir-20a Glioma 26337869 "In summary, DNMT1 mediated chemosensitivity by reducing methylation of the microRNA-20a promoter in glioma cells." epigenetics hsa-mir-125b Neoplasms [unspecific] 26354435 "Taken together, our results demonstrated that miR-125b mediates PAR2-induced cancer cell migration by targeting Gab2 and that NSun2-dependent RNA methylation contributes to the down-regulation of miR-125b by PAR2 signaling. " epigenetics hsa-let-7 Glioma 26463235 epigenetic modification is a crucial mechanism for controlling the expression of miR-126 in glioma. epigenetics hsa-mir-126 Rheumatoid Arthritis 26464634 Correlation between miR-126 expression and DNA hypomethylation of CD4+ T cells in rheumatoid arthritis patients. epigenetics hsa-mir-122 Germ Cell Tumor 26497383 "Cross platform analysis of methylation, miRNA and stem cell gene expression data in germ cell tumors highlights characteristic differences by tumor histology." epigenetics hsa-mir-302a Germ Cell Tumor 26497383 "Cross platform analysis of methylation, miRNA and stem cell gene expression data in germ cell tumors highlights characteristic differences by tumor histology." epigenetics hsa-mir-302d Germ Cell Tumor 26497383 "Cross platform analysis of methylation, miRNA and stem cell gene expression data in germ cell tumors highlights characteristic differences by tumor histology." epigenetics hsa-mir-371 Germ Cell Tumor 26497383 "Cross platform analysis of methylation, miRNA and stem cell gene expression data in germ cell tumors highlights characteristic differences by tumor histology." epigenetics hsa-mir-373 Germ Cell Tumor 26497383 "Cross platform analysis of methylation, miRNA and stem cell gene expression data in germ cell tumors highlights characteristic differences by tumor histology." epigenetics hsa-mir-129-2 Breast Neoplasms 26519551 "In summary, the obtained data indicate the involvement of methylation in the down-regulation of the studied coding and miRNA genes and suggest the involvement of miR-129-2 in the deregulation of RASSF1(A) via a direct interaction or/and mediators in common pathways (according to KEGG, Gene Ontology (FDR < 0.01), and GeneCards data) in the examined gynecological tumors." epigenetics hsa-mir-129-2 Ovarian Neoplasms 26519551 "In summary, the obtained data indicate the involvement of methylation in the down-regulation of the studied coding and miRNA genes and suggest the involvement of miR-129-2 in the deregulation of RASSF1(A) via a direct interaction or/and mediators in common pathways (according to KEGG, Gene Ontology (FDR < 0.01), and GeneCards data) in the examined gynecological tumors." epigenetics hsa-mir-9-1 Breast Neoplasms 26519551 "In summary, the obtained data indicate the involvement of methylation in the down-regulation of the studied coding and miRNA genes and suggest the involvement of miR-129-2 in the deregulation of RASSF1(A) via a direct interaction or/and mediators in common pathways (according to KEGG, Gene Ontology (FDR < 0.01), and GeneCards data) in the examined gynecological tumors." epigenetics hsa-mir-9-1 Ovarian Neoplasms 26519551 "In summary, the obtained data indicate the involvement of methylation in the down-regulation of the studied coding and miRNA genes and suggest the involvement of miR-129-2 in the deregulation of RASSF1(A) via a direct interaction or/and mediators in common pathways (according to KEGG, Gene Ontology (FDR < 0.01), and GeneCards data) in the examined gynecological tumors." epigenetics hsa-mir-34b Leukemia 26524015 "CpG island methylation of miR-34b promoter region in leukemia cell lines can decrease the expression levels of miR-34b, which is also the reason why miR-34b can reduce the inhibition of cell proliferation, thus miR-34b might be a tumor suppressor gene involved in the regulation of leukemia." epigenetics hsa-mir-29c Breast Neoplasms 26539832 Molecular Subtype-Specific Expression of MicroRNA-29c in Breast Cancer Is Associated with CpG Dinucleotide Methylation of the Promoter. epigenetics hsa-mir-24 Colon Adenoma 26559563 "Butyrate and partial TSA reduced the expression of miR-135a, miR-135b, miR-24 and miR-let-7a (~0.5-fold, 24 h) and miR-24, miR-106b and miR-let-7a (~0.5-0.7-fold, 48 h) in LT97 cells." epigenetics hsa-mir-143 Vascular Disease [unspecific] 26573388 "Taken together, these findings suggest that DNMT3a is a direct target of miR-143, and that the upregulation of DNMT3 is responsible for the hypermethylation of miR-143 in Hcy-induced VSMC proliferation." epigenetics hsa-mir-145 "Adenocarcinoma, Lung" 26582602 "Taken together, DNA hyper-methylation in the miR-145 promoter region reduced its expression in LAC and miR-145 expression level might serve as a novel prognostic biomarker." epigenetics hsa-mir-218 "Carcinoma, Esophageal" 26610476 "In conclusion, our results support that aberrant CpG hypermethylation at least partly accounts for miR-218 silencing in ESCC, which impairs its tumor-suppressive function." epigenetics hsa-mir-148a Skin Neoplasms 26638007 "Taken together, the expression of miR-148a was regulated by DNA methylation and targeted by TGIF2.Its methylation may be a potential prognostic indicator in skin cancer." epigenetics hsa-mir-125a Colorectal Carcinoma 26693202 "Our results suggest that DNA hypermethylation may be involved in the inactivation of miR-125a and miR-125b in CRC, and hypermethylation of miR-125 is a potential biomarker for clinical outcome." epigenetics hsa-mir-125b Colorectal Carcinoma 26693202 "Our results suggest that DNA hypermethylation may be involved in the inactivation of miR-125a and miR-125b in CRC, and hypermethylation of miR-125 is a potential biomarker for clinical outcome." epigenetics hsa-mir-34c Colorectal Carcinoma 26704889 "In conclusion, our results suggested the existence of E2F1-miR-34c-SCF negative feedback loop which was interrupted by the hyper-methylation of miR-34c promoter in CRC cells and increased cell proliferation." epigenetics hsa-mir-140 Osteoarthritis 26723856 "Some miRNA have also been identified and more extensively characterized, such as delineation of the role played by miR-140 in chondrogenesis, followed by the discovery of numerous miRNA potentially involved in the epigenetic regulation of osteoarthritic disease." epigenetics hsa-mir-21 Colorectal Carcinoma 26787105 This study suggests a high frequency of miR-21 overexpression and aberrant promoter methylation in down-regulation of PTEN expression in colorectal carcinoma. Loss of PTEN may be a prognostic factor for patients with CRC. epigenetics hsa-mir-133a Cardiomegaly 26830171 Phe exposure led to methylation of CpG sites within the miR-133a locus and reduced miR-133a expression in H9C2 cells epigenetics hsa-mir-34b Sarcomatoid Mesothelioma 26870271 miR-34b/c was heavily methylated in 2/4 established MPM cell lines epigenetics hsa-mir-34c Sarcomatoid Mesothelioma 26870271 miR-34b/c was heavily methylated in 2/4 established MPM cell lines epigenetics hsa-mir-34a Ovarian Neoplasms 26879132 "We demonstrated a clinical independent role of miR-34a in epithelial ovarian cancers. Moreover, we corroborated the correlation between miR-34a expression and its promoter methylation in a large set of ovarian cancers. The inverse association between miR-34a expression and grading, p53 mutation status and dualistic tumor type classification, together with its prognostic relevance may underline the tumor-suppressive character of miR-34a in ovarian cancer." epigenetics hsa-mir-296 Glioblastoma 26898758 We show that miR-296-5p expression is repressed in a DNA methylation-dependent manner under conditions that promote GBM cell stemness epigenetics hsa-mir-378 "Leukemia, Myeloid, Chronic" 26913395 Methylation of miR-378 in Chronic Myeloid Leukemia. epigenetics hsa-mir-181c Glioblastoma 26983574 Epigenetic silencing of miR-181c by DNA methylation in glioblastoma cell lines. epigenetics hsa-mir-10b "Squamous Cell Carcinoma, Head and Neck" 27002147 DOT1L-associated epigenetic changes induced by HA play pivotal roles in miR-10 production leading to up-regulation of RhoGTPase and survival proteins. epigenetics hsa-mir-497 Hematologic Neoplasms 27075177 "Strikingly, low-dose decitabine was able to augment chemosensitivity in cancer stem cells, likely by the upregulation of miRNA-497" epigenetics hsa-mir-155 Lymphoma 27110708 DNA methylation regulates miR-155 expression. epigenetics hsa-mir-30d Ovarian Neoplasms 27141829 TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells epigenetics hsa-mir-193b "Adenocarcinoma, Esophageal" 27176876 Aberrant methylation of microRNA-193b in human Barrett's esophagus and esophageal adenocarcinoma epigenetics hsa-mir-141 Prostate Neoplasms 27198154 miR-200c and miR-141 are under epigenetic regulation in PCa cells. epigenetics hsa-mir-200c Prostate Neoplasms 27198154 miR-200c and miR-141 are under epigenetic regulation in PCa cells. epigenetics hsa-mir-153 Glioblastoma 27215075 MiR-153 as a Tumor Suppressor in Glioblastoma Multiforme is Downregulated by DNA Methylation. epigenetics hsa-mir-211 Melanoma 27237979 DNMT1 mediated promoter methylation is a mechanism of miRNA suppression in melanoma epigenetics hsa-mir-200b Cervical Neoplasms 27272214 Long noncoding RNA PVT1 promotes cervical cancer progression through epigenetically silencing miR-200b epigenetics hsa-mir-27b Breast Neoplasms 27363334 MiR-27b is epigenetically downregulated in tamoxifen resistant breast cancer cells epigenetics hsa-mir-19a Breast Neoplasms 27445062 "CAP treatment of MCF-7 induced hypermethylation at the promoter CpG sites and downregulation of miR-19a, which was known as an oncomiR." epigenetics hsa-mir-34a "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 27450916 "Our study revealed that miR-34a promoter hypermethylation was a risk factor for LSCC, played a critical role in the disease progression and metastasis, and could serve as a poor prognostic factor for LSCC." epigenetics hsa-mir-375 "Carcinoma, Breast" 27466996 "MiR-375 is downregulated in MCF-7/ADM and MCF-7/PTX cells, and its downregulation is a result of promoter methylation." epigenetics hsa-mir-152 "Carcinoma, Breast" 27475839 DNA methylation and not H3K4 trimethylation dictates the expression status of miR-152 gene which inhibits migration of breast cancer cells via DNMT1/CDH1 loop. epigenetics hsa-mir-615 "Carcinoma, Hepatocellular" 27487123 "In conclusion, our findings characterize miR-615-5p as an important epigenetically silenced miRNA involved in the Rab-Ras pathway in hepatocellular carcinoma and expand our understanding of the molecular mechanism underlying hepatocarcinogenesis and metastasis." epigenetics hsa-let-7b "Carcinoma, Colon" 27525719 "G9a binds with and stabilizes RelB, thereby recruiting DNA methyltransferase 3 on the Let-7b promoter and repressing its expression." epigenetics hsa-mir-34a "Carcinoma, Bladder" 27557899 MicroRNA epigenetic signatures in human disease. epigenetics hsa-mir-34b Bladder Neoplasms 27557899 MicroRNA epigenetic signatures in human disease. epigenetics hsa-mir-34c "Carcinoma, Bladder" 27557899 MicroRNA epigenetic signatures in human disease. epigenetics hsa-mir-125b Chondrosarcoma 27576314 Induction of the mesenchymal to epithelial transition by demethylation-activated microRNA-125b is involved in the anti-migration/invasion effects of arsenic trioxide on human chondrosarcoma. epigenetics hsa-mir-429 Cholangiocarcinoma 27593557 Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinoma. epigenetics hsa-mir-17 Bronchopulmonary Dysplasia 27694474 our data support a plausible role for epigenetically altered miR-17/92 cluster in the pathogenesis of severe BPD epigenetics hsa-mir-18 Bronchopulmonary Dysplasia 27694474 our data support a plausible role for epigenetically altered miR-17/92 cluster in the pathogenesis of severe BPD epigenetics hsa-mir-19a Bronchopulmonary Dysplasia 27694474 our data support a plausible role for epigenetically altered miR-17/92 cluster in the pathogenesis of severe BPD epigenetics hsa-mir-19b-1 Bronchopulmonary Dysplasia 27694474 our data support a plausible role for epigenetically altered miR-17/92 cluster in the pathogenesis of severe BPD epigenetics hsa-mir-20a Bronchopulmonary Dysplasia 27694474 our data support a plausible role for epigenetically altered miR-17/92 cluster in the pathogenesis of severe BPD epigenetics hsa-mir-92-1 Bronchopulmonary Dysplasia 27694474 our data support a plausible role for epigenetically altered miR-17/92 cluster in the pathogenesis of severe BPD epigenetics hsa-mir-200c "Carcinoma, Breast" 27717206 Epigenetic silencing of miR-200c in breast cancer is associated with aggressiveness and is modulated by ZEB1. epigenetics hsa-mir-200 Ovarian Serous Cystadenocarcinoma 27746113 DNA methylation-regulated microRNA pathways in ovarian serous cystadenocarcinoma: A meta-analysis. epigenetics hsa-mir-200 "Leukemia, Myeloid, Acute" 27756750 epigenetic silencing of the miR-200 family microRNAs affects ZEB2 expression epigenetics hsa-mir-124 Cervical Neoplasms 27765948 Suppression of iASPP-dependent aggressiveness in cervical cancer through reversal of methylation silencing of microRNA-124. epigenetics hsa-mir-126 "Carcinoma, Hepatocellular" 27774652 METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N6 -methyladenosine-dependent primary MicroRNA processing. epigenetics hsa-mir-149 Glioblastoma 27783537 "MicroRNA-149 is epigenetically silenced tumor-suppressive microRNA, involved in cell proliferation and downregulation of AKT1 and cyclin?D1 in human glioblastoma multiforme." epigenetics hsa-mir-181a Neurodegenerative Diseases [unspecific] 27789312 PPAR¦Â/¦Ä activation protects against corticosterone-induced ER?stress?in astrocytes by inhibiting the CpG hypermethylation of?microRNA-181a. epigenetics hsa-mir-124a Rheumatoid Arthritis 27824863 Demethylation of MicroRNA-124a Genes Attenuated Proliferation of Rheumatoid Arthritis Derived Fibroblast-Like Synoviocytes and Synthesis of Tumor Necrosis Factor-¦Á. epigenetics hsa-mir-107 "Carcinoma, Breast" 27830681 Novel miRNA genes hypermethylated in breast cancer. epigenetics hsa-mir-1258 "Carcinoma, Breast" 27830681 Novel miRNA genes hypermethylated in breast cancer. epigenetics hsa-mir-130b "Carcinoma, Breast" 27830681 Novel miRNA genes hypermethylated in breast cancer. epigenetics hsa-mir-132 "Carcinoma, Breast" 27830681 Novel miRNA genes hypermethylated in breast cancer. epigenetics hsa-mir-137 "Carcinoma, Breast" 27830681 Novel miRNA genes hypermethylated in breast cancer. epigenetics hsa-mir-378a Liver Cirrhosis 27855367 The Epigenetically-Regulated microRNA-378a Targets TGF-¦Â2 in TGF-¦Â1-Treated Hepatic Stellate Cells. epigenetics hsa-mir-148a Osteoporosis 27900532 MiR-148a the epigenetic regulator of bone homeostasis is increased in plasma of osteoporotic postmenopausal women. epigenetics hsa-mir-124 "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-125b "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-127 "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-132 "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-137 "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-148a "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-191 "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-193a "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-203 "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-212 "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-34b "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-375 "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-9 "Carcinoma, Breast" 27998789 DNA methylation contributes to deregulation of 12 cancer-associated microRNAs and breast cancer progression. epigenetics hsa-mir-149 Hematologic Neoplasms 28035377 Histone deacetylases meet microRNA-associated MMP-9 expression regulation in glucocorticoid-sensitive and -resistant cell lines. epigenetics hsa-mir-520c Hematologic Neoplasms 28035377 Histone deacetylases meet microRNA-associated MMP-9 expression regulation in glucocorticoid-sensitive and -resistant cell lines. epigenetics hsa-mir-106b "Adenocarcinoma, Esophageal" 28049580 Epigenetic regulation on the gene expression signature in esophagus adenocarcinoma. epigenetics hsa-mir-129 "Carcinoma, Urothelial" 28081549 MicroRNA promoter methylation: a new tool for accurate detection of urothelial carcinoma. epigenetics hsa-mir-663a "Carcinoma, Urothelial" 28081549 MicroRNA promoter methylation: a new tool for accurate detection of urothelial carcinoma. epigenetics hsa-mir-200 "Carcinoma, Endometrioid Endometrial" 28088687 Whole-Genome DNA Methylation Profiling Identifies Epigenetic Signatures of Uterine Carcinosarcoma. epigenetics hsa-mir-193b Prostate Neoplasms 28143614 MiR-193b promoter methylation accurately detects prostate cancer in urine sediments and miR-34b/c or miR-129-2 promoter methylation define subsets of clinically aggressive tumors. epigenetics hsa-mir-371 Testicular Germ Cell Tumor 28199193 Epigenetic and risk factors of testicular germ cell tumors: a brief review. epigenetics hsa-mir-373 Testicular Germ Cell Tumor 28199193 Epigenetic and risk factors of testicular germ cell tumors: a brief review. epigenetics hsa-mir-1 Heart Diseases [unspecific] 28209718 Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo. epigenetics hsa-mir-133 Heart Diseases [unspecific] 28209718 Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo. epigenetics hsa-mir-208 Heart Diseases [unspecific] 28209718 Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo. epigenetics hsa-mir-499 Heart Diseases [unspecific] 28209718 Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo. epigenetics hsa-mir-137 "Carcinoma, Lung, Non-Small-Cell" 28223039 Oncogene LSD1 is epigenetically suppressed by miR-137 overexpression in human non-small cell lung cancer. epigenetics hsa-mir-183 "Carcinoma, Hepatocellular" 28321157 hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma. epigenetics hsa-mir-210 Colorectal Carcinoma 28364795 The significance of DNA methylation profile in metastasis-related genes for the progression of colorectal cancer. epigenetics hsa-mir-34 Colorectal Carcinoma 28364795 The significance of DNA methylation profile in metastasis-related genes for the progression of colorectal cancer. epigenetics hsa-mir-9 Colorectal Carcinoma 28364795 The significance of DNA methylation profile in metastasis-related genes for the progression of colorectal cancer. epigenetics hsa-mir-370 Cholangiocarcinoma 28545228 Aberrant DNA Methylation as a Biomarker and a Therapeutic Target of Cholangiocarcinoma. epigenetics hsa-mir-10b Atherosclerosis 28601079 Variability of Methylation Profiles of CpG Sites in microrNA Genes in Leukocytes and Vascular Tissues of Patients with Atherosclerosis. epigenetics hsa-mir-200 Lung Neoplasms 28698146 Epigenetic regulation of epithelial-mesenchymal transition by KDM6A histone demethylase in lung cancer cells. epigenetics hsa-mir-200c Breast Neoplasms 28724364 Tamoxifen reverses epithelial-mesenchymal transition by demethylating miR-200c in triple-negative breast cancer cells. epigenetics hsa-mir-21 Multiple Sclerosis 28766461 Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes. epigenetics hsa-mir-21 Nervous System Diseases [unspecific] 28903050 Changes in the Coding and Non-coding Transcriptome and DNA Methylome that Define the Schwann Cell Repair Phenotype after Nerve Injury. epigenetics hsa-mir-34a Cholangiocarcinoma 28923203 Epigenetic Silencing of miRNA-34a in Human Cholangiocarcinoma via EZH2 and DNA Methylation: Impact on Regulation of Notch Pathway. epigenetics hsa-mir-142 "Carcinoma, Hepatocellular" 28963738 Loss-of-function of miR-142 by hypermethylation promotes TGF-¦Â-mediated tumour growth and metastasis in hepatocellular carcinoma. epigenetics hsa-mir-200b Cervical Neoplasms 29077234 DNA methylation regulated microRNAs in human cervical cancer. epigenetics hsa-mir-342 Multiple Myeloma 29242101 Epigenetic silencing of EVL/miR-342 in multiple myeloma epigenetics hsa-mir-101 Glioblastoma 29251856 Studies of intragenic and distant intergenic alterations in DNA methylation will help elucidate the nature of epigenetic deregulation in glioblastoma epigenetics hsa-mir-29a "Lymphoma, Burkitt" 29318382 methylation-mediated miR-29 epigenetic silencing may occur during BL development epigenetics hsa-mir-22 Cholangiocarcinoma 29406621 MicroRNA (miR)-433 and miR-22 dysregulations induce histone-deacetylase-6 overexpression and ciliary loss in cholangiocarcinoma. epigenetics hsa-mir-433 Cholangiocarcinoma 29406621 MicroRNA (miR)-433 and miR-22 dysregulations induce histone-deacetylase-6 overexpression and ciliary loss in cholangiocarcinoma. epigenetics hsa-mir-196b Prostate Neoplasms 29536528 "CLCA2 epigenetic regulation by CTBP1, HDACs, ZEB1, EP300 and miR-196b-5p impacts prostate cancer cell adhesion and EMT in metabolic syndrome disease." epigenetics hsa-mir-34a Preeclampsia 29557690 Hypomethylation of the miRNA-34a gene promoter is associated with Severe Preeclampsia epigenetics hsa-mir-1179 "Carcinoma, Lung, Non-Small-Cell" 29570800 DNA methylation of microRNA-coding genes in non-small-cell lung cancer patients. epigenetics hsa-mir-148a Prostate Neoplasms 29596883 miR-148a is silenced by DNA methylation and ectopic expression of miR-148a suppresses DNMT1 expression and induced apoptotic genes expression in hormone-refractory prostate cancer cells epigenetics hsa-mir-375 "Carcinoma, Ovarian" 29631007 Novel miRNA genes deregulated by aberrant methylation in ovarian carcinoma are involved in metastasis epigenetics hsa-mir-449a "Carcinoma, Pancreatic" 29684857 MicroRNA-449a functions as a tumor suppressor in pancreatic cancer by the epigenetic regulation of ATDC expression. epigenetics hsa-mir-34c Colorectal Carcinoma 29701273 SATB2 targeted by methylated miR-34c-5p suppresses proliferation and metastasis attenuating the epithelial-mesenchymal transition in colorectal cancer. epigenetics hsa-mir-483 "Carcinoma, Lung, Non-Small-Cell" 29717264 Epigenetic silencing of miR-483-3p promotes acquired gefitinib resistance and EMT in EGFR-mutant NSCLC by targeting integrin ¦Â3. epigenetics hsa-mir-570 Osteosarcoma 29795113 Inhibition of LCMR1 and ATG12 by demethylation-activated miR-570-3p is involved in the anti-metastasis effects of metformin on human osteosarcoma. epigenetics hsa-mir-1271 Gastric Neoplasms 29862663 Epigenetic silencing of miR-1271 enhances MEK1 and TEAD4 expression in gastric cancer. epigenetics hsa-mir-155 Glioma 29885519 Methylation-mediated miR-155-FAM133A axis contributes to the attenuated invasion and migration of IDH mutant gliomas. epigenetics hsa-mir-34b Neoplasms [unspecific] 29893976 Regulation of miR-34b/c-targeted gene expression program by SUMOylation. epigenetics hsa-mir-34c Neoplasms [unspecific] 29893976 Regulation of miR-34b/c-targeted gene expression program by SUMOylation. epigenetics hsa-mir-34 "Carcinoma, Breast" 29916548 Methylation profiles of miR34 gene family in Vietnamese patients suffering from breast and lung cancers. epigenetics hsa-mir-137 Endometrial Neoplasms 29955087 miR-137 is a tumor suppressor in endometrial cancer and is repressed by DNA hypermethylation. epigenetics hsa-mir-124 "Carcinoma, Cervical" 29960712 "Methylation of the hsa-miR-124, SOX1, TERT, and LMX1A genes as biomarkers for precursor lesions in cervical cancer." epigenetics hsa-mir-145 Ovarian Neoplasms 29993160 Double-negative feedback interaction between DNA methyltransferase 3A and microRNA-145 in the Warburg effect of ovarian cancer cells. epigenetics hsa-mir-125a Gastric Neoplasms 30117667 Epigenetic silenced miR-125a-5p could be self-activated through targeting Suv39H1 in gastric cancer. epigenetics hsa-mir-122 "Carcinoma, Hepatocellular" 30195653 LncRNA HOTAIR epigenetically suppresses miR-122 expression in hepatocellular carcinoma via DNA methylation. epigenetics hsa-mir-4532 "Carcinoma, Breast" 30202238 Downregulation of hypermethylated in cancer-1 by miR-4532 promotes adriamycin resistance in breast cancer cells. epigenetics hsa-mir-873 Liver Cirrhosis 30237481 MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis. epigenetics hsa-mir-486 Colorectal Carcinoma 30305607 DNA-methylation-mediated silencing of miR-486-5p promotes colorectal cancer proliferation and migration through activation of PLAGL2/IGF2/¦Â-catenin signal pathways. epigenetics hsa-mir-388 Gastric Neoplasms 30308487 Hypermethylation of miR-338-3p and Impact of its Suppression on Cell Metastasis Through N-Cadherin Accumulation at the Cell -Cell Junction and Degradation of MMP in Gastric Cancer. epigenetics hsa-mir-107 Ovarian Neoplasms 30363055 "Hypermethylation of miR-107, miR-130b, miR-203a, miR-1258 Genes Associated with Ovarian Cancer Development and Metastasis" epigenetics hsa-mir-1258 Ovarian Neoplasms 30363055 "Hypermethylation of miR-107, miR-130b, miR-203a, miR-1258 Genes Associated with Ovarian Cancer Development and Metastasis" epigenetics hsa-mir-130b Ovarian Neoplasms 30363055 "Hypermethylation of miR-107, miR-130b, miR-203a, miR-1258 Genes Associated with Ovarian Cancer Development and Metastasis" epigenetics hsa-mir-203a Ovarian Neoplasms 30363055 "Hypermethylation of miR-107, miR-130b, miR-203a, miR-1258 Genes Associated with Ovarian Cancer Development and Metastasis" epigenetics hsa-mir-132 "Carcinoma, Pancreatic" 30387838 Dexamethasone-induced inhibition of miR-132 via methylation promotes TGF-¦Â-driven progression of pancreatic cancer. genetics_GWAS hsa-mir-142 Leukemia 15737576 Some human miRNAs are linked to leukemias: the miR-15a/miR-16 locus is frequently deleted or down-regulated in patients with B-cell chronic lymphocytic leukemia and miR-142 is at a translocation site found in a case of aggressive B-cell leukemia. genetics_GWAS hsa-mir-189 Tourette Syndrome 16224024 we identified a frameshift mutation and two independent occurrences of the identical variant in the binding site for microRNA hsa-miR-189 genetics_GWAS hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 mutation genetics_GWAS hsa-mir-187 "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 mutation genetics_GWAS hsa-mir-206 "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 mutation genetics_GWAS hsa-mir-27b "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 mutation genetics_GWAS hsa-mir-29b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 16251535 mutation genetics_GWAS hsa-mir-103a-2 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-103a-2 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-103a-2 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-106b Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-106b Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-106b Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-1-1 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-1-1 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-1-1 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-133a-2 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-133a-2 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-133a-2 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-135b Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-135b Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-135b Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-151a Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-151a Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-151a Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-153-2 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-153-2 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-153-2 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-17 Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-17 Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-17 Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-18a Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-18a Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-18a Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-194-1 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-194-1 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-194-1 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-199a-2 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-199a-2 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-199a-2 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-19a Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-19a Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-19a Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-19b-1 Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-19b-1 Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-19b-1 Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-200a Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-200a Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-200a Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-200b Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-200b Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-200b Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-20a Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-20a Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-20a Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-214 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-214 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-214 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-215 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-215 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-215 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-218-1 Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-218-1 Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-218-1 Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-219-1 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-219-1 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-219-1 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-25 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-25 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-25 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-296 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-296 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-296 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-302a Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-302a Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-302a Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-302b Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-302b Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-302b Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-302c Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-302c Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-302c Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-302d Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-302d Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-302d Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-30b Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-30b Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-30b Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-30d Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-30d Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-30d Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-320a Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-320a Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-320a Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-338 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-338 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-338 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-339 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-339 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-339 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-367 Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-367 Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-367 Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-383 Breast Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-383 Melanoma 16754881 copy number loss genetics_GWAS hsa-mir-383 Ovarian Neoplasms 16754881 copy number loss genetics_GWAS hsa-mir-429 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-429 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-429 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-488 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-488 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-488 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-9-1 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-9-1 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-9-1 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-93 Breast Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-93 Melanoma 16754881 copy number gain genetics_GWAS hsa-mir-93 Ovarian Neoplasms 16754881 copy number gain genetics_GWAS hsa-mir-1 Vascular Hypertrophy 17381315 we have identified an A-to-G transition in the 3'UTR of the GDF8 gene that reveals an illegitimate target site for microRNAs miR-1 and miR-206 that are highly expressed in skeletal muscle. genetics_GWAS hsa-mir-206 Vascular Hypertrophy 17381315 we have identified an A-to-G transition in the 3'UTR of the GDF8 gene that reveals an illegitimate target site for microRNAs miR-1 and miR-206 that are highly expressed in skeletal muscle. genetics_GWAS hsa-mir-146a Thyroid Neoplasms 17468766 "somatic mutations altering binding sites for miR-221, miR-222 and miR-146 have been observed in the 3'UTR of the KIT oncogene in papillary thyroid carcinoma." genetics_GWAS hsa-mir-146b Thyroid Neoplasms 17468766 "somatic mutations altering binding sites for miR-221, miR-222 and miR-146 have been observed in the 3'UTR of the KIT oncogene in papillary thyroid carcinoma." genetics_GWAS hsa-mir-221 Thyroid Neoplasms 17468766 "somatic mutations altering binding sites for miR-221, miR-222 and miR-146 have been observed in the 3'UTR of the KIT oncogene in papillary thyroid carcinoma." genetics_GWAS hsa-mir-222 Thyroid Neoplasms 17468766 "somatic mutations altering binding sites for miR-221, miR-222 and miR-146 have been observed in the 3'UTR of the KIT oncogene in papillary thyroid carcinoma." genetics_GWAS hsa-mir-198 Schizophrenia 17849003 SNP (rs1700) disease susceptibility genetics_GWAS hsa-mir-206 Schizophrenia 17849003 SNP (rs17578796) disease susceptibility genetics_GWAS hsa-mir-146a Thyroid Neoplasms 18474871 "Thus, our data suggest that a common polymorphism in pre-miR-146a affects the miR expression, contributes to the genetic predisposition to PTC, and plays a role in the tumorigenesis through somatic mutation." genetics_GWAS hsa-mir-196a-2 Lung Neoplasms 18521189 "Therefore, the rs11614913 SNP in hsa-mir-196a2 may be a prognostic biomarker for NSCLC." genetics_GWAS hsa-mir-510 Irritable Bowel Syndrome 18614545 First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor type 3E gene with diarrhea predominant irritable bowel syndrome. genetics_GWAS hsa-mir-146a Breast Neoplasms 18634034 miR-146: rs2910164 were associated with increased risk of breast cancer in Chinese women genetics_GWAS hsa-mir-146b Breast Neoplasms 18634034 miR-146: rs2910164 were associated with increased risk of breast cancer in Chinese women genetics_GWAS hsa-mir-149 Breast Neoplasms 18634034 miR-149: rs2292832 were associated with increased risk of breast cancer in Chinese women genetics_GWAS hsa-mir-196a-2 Breast Neoplasms 18634034 miR-196a-2: rs11614913 were associated with increased risk of breast cancer in Chinese women genetics_GWAS hsa-mir-499a Breast Neoplasms 18634034 miR-499: rs3746444 were associated with increased risk of breast cancer in Chinese women genetics_GWAS hsa-mir-146a Breast Neoplasms 18660546 miR-146a: A functional polymorphism (rs2910164) in the miR-146a gene and age of familial breast/ovarian cancer diagnosis genetics_GWAS hsa-mir-146a Ovarian Neoplasms 18660546 miR-146a: A functional polymorphism (rs2910164) in the miR-146a gene and age of familial breast/ovarian cancer diagnosis genetics_GWAS hsa-mir-146a "Carcinoma, Hepatocellular" 18711148 miR-146a: A functional polymorphism (rs2910164) in the miR-146a gene is associated with the risk for hepatocellular carcinoma genetics_GWAS hsa-mir-659 Dementia 18723524 miR-659: Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia genetics_GWAS hsa-let-7a "Carcinoma, Lung, Non-Small-Cell" 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. genetics_GWAS hsa-let-7a-1 "Carcinoma, Lung, Non-Small-Cell" 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. genetics_GWAS hsa-let-7a-1 Lung Neoplasms 18922928 let-7a: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk genetics_GWAS hsa-let-7a-2 "Carcinoma, Lung, Non-Small-Cell" 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. genetics_GWAS hsa-let-7a-2 Lung Neoplasms 18922928 let-7a: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk genetics_GWAS hsa-let-7a-3 "Carcinoma, Lung, Non-Small-Cell" 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. genetics_GWAS hsa-let-7a-3 Lung Neoplasms 18922928 let-7a: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk genetics_GWAS hsa-let-7b "Carcinoma, Lung, Non-Small-Cell" 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. genetics_GWAS hsa-let-7b Lung Neoplasms 18922928 let-7b: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk genetics_GWAS hsa-let-7c Lung Neoplasms 18922928 let-7c: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk genetics_GWAS hsa-let-7d "Carcinoma, Lung, Non-Small-Cell" 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. genetics_GWAS hsa-let-7d Lung Neoplasms 18922928 let-7d: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk genetics_GWAS hsa-let-7e Lung Neoplasms 18922928 let-7e: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk genetics_GWAS hsa-let-7f-1 Lung Neoplasms 18922928 let-7f: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk genetics_GWAS hsa-let-7f-2 Lung Neoplasms 18922928 let-7f: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk genetics_GWAS hsa-let-7g "Carcinoma, Lung, Non-Small-Cell" 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. genetics_GWAS hsa-let-7g Lung Neoplasms 18922928 let-7g: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk genetics_GWAS hsa-let-7i Lung Neoplasms 18922928 let-7i: A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk genetics_GWAS hsa-mir-17 Breast Neoplasms 19048628 miR-17: mutations genetics_GWAS hsa-mir-30c-1 Breast Neoplasms 19048628 miR-30c-1: mutations genetics_GWAS hsa-mir-122 Hypertension 19067360 a polymorphism of the 3'UTR of the SLC7A1 gene affects the binding with miR-122 genetics_GWAS hsa-mir-146a Thyroid Neoplasms 19164563 miR-146a: SNP rs2910164 contribute to thyroid cancer genetics_GWAS hsa-mir-96 Sensorineural Hearing Loss 19363478 miR-96: An ENU-induced mutation genetics_GWAS hsa-mir-96 Sensorineural Hearing Loss 19363479 miR-96: Mutations in the seed region genetics_GWAS hsa-mir-128 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. genetics_GWAS hsa-mir-148a Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. genetics_GWAS hsa-mir-148b Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. genetics_GWAS hsa-mir-152 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. genetics_GWAS hsa-mir-485 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. genetics_GWAS hsa-mir-509 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. genetics_GWAS hsa-mir-765 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. genetics_GWAS hsa-mir-125b Breast Neoplasms 19738052 A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis. genetics_GWAS hsa-mir-196a-2 Gastric Neoplasms 19834808 miR-196a-2:Association of microRNA-196a-2 gene polymorphism with gastric cancer risk genetics_GWAS hsa-mir-499 Breast Neoplasms 19847796 "Recently, the SNPs rs11614913 in hsa-mir-196a2 and rs3746444 in hsa-mir-499 were reported to be associated with increased breast cancer risk, and the SNP rs2910164 in hsa-mir-146a was shown to have an effect on age of breast cancer diagnosis." genetics_GWAS hsa-mir-146a Prostate Neoplasms 19902466 "The natural genetic variation in pre-miR-146a affects the amount of mature miR-146a, contributes to the genetic predisposition to CaP." genetics_GWAS hsa-mir-15a Multiple Myeloma 20031211 miR-15a:Micro-RNA-15a and micro-RNA-16 expression and chromosome 13 deletions in multiple myeloma genetics_GWAS hsa-mir-16-1 Multiple Myeloma 20031211 miR-16:Micro-RNA-15a and micro-RNA-16 expression and chromosome 13 deletions in multiple myeloma genetics_GWAS hsa-mir-16-2 Multiple Myeloma 20031211 miR-16:Micro-RNA-15a and micro-RNA-16 expression and chromosome 13 deletions in multiple myeloma genetics_GWAS hsa-mir-492 Colorectal Carcinoma 20044760 "mir-492:In a univariate analysis, the progression-free survival of the patients with the combined mir492 C/G and G/G genotype was significantly worse than that of the patients with the mir492 C/C genotype (rs2289030) (P value = 0.0426)" genetics_GWAS hsa-mir-218-1 Urinary Bladder Cancer 20163849 miR-218:Polymorphisms involved in the miR-218-LAMB3 pathway and susceptibility of cervical cancer genetics_GWAS hsa-mir-218-2 Urinary Bladder Cancer 20163849 miR-218:Polymorphisms involved in the miR-218-LAMB3 pathway and susceptibility of cervical cancer genetics_GWAS hsa-mir-191 Ovarian Neoplasms 20167074 Novel genetic variants in miR-191 gene and familial ovarian cancer genetics_GWAS hsa-mir-196a-2 "Carcinoma, Hepatocellular" 20188135 miR-196a2:MIR196A2 polymorphism was associated with susceptibility to HBV-related HCC in a maleChinese population. genetics_GWAS hsa-mir-196a-1 Glioma 20229273 A polymorphism of microRNA196a genome region was associated with decreased risk of glioma in Chinese population genetics_GWAS hsa-mir-196a-2 Glioma 20229273 A polymorphism of microRNA196a genome region was associated with decreased risk of glioma in Chinese population genetics_GWAS hsa-mir-128-2 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 20237425 A novel mutation in the miR-128b gene reduces miRNA processing and leads to glucocorticoid resistance of MLL-AF4 acute lymphocytic leukemia cells. genetics_GWAS hsa-mir-30e Schizophrenia 20347265 miR-30e:mir-30e ss178077483 plays a role in schizophrenia susceptibility genetics_GWAS hsa-mir-204 Neoplasms [unspecific] 20439436 "miR-204:hsa-miR-30 and hsa-miR-204, were found to be physically altered at the DNA copy number level as well" genetics_GWAS hsa-mir-20a Neoplasms [unspecific] 20439436 mir-20a:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted genetics_GWAS hsa-mir-30a Neoplasms [unspecific] 20439436 "miR-30:hsa-miR-103/106 were downgraded in cancer, whereas hsa-miR-30 became most prominent" genetics_GWAS hsa-mir-125b-1 "Leukemia, Biphenotypic, Acute" 20485370 miR-125b-1:A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia genetics_GWAS hsa-mir-196a-2 "Cardiomyopathy, Dilated" 20488170 mir-196a2:Common genetic polymorphisms in pre-microRNAs were associated with increased risk of dilated cardiomyopathy genetics_GWAS hsa-mir-499a "Cardiomyopathy, Dilated" 20488170 mir-499:Common genetic polymorphisms in pre-microRNAs were associated with increased risk of dilated cardiomyopathy genetics_GWAS hsa-mir-499 "Squamous Cell Carcinoma, Head and Neck" 20549817 "Of the 4 SNPs that were studied, the hsa-mir-499 AG and GG genotypes were associated with a reduced risk of SCCHN" genetics_GWAS hsa-mir-30e Schizophrenia 20579744 Our previous study revealed a strong association between the polymorphism ss178077483 in the miRNA-30e precursor (pre-miR-30e) and the risk of SCZ. genetics_GWAS hsa-mir-126 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 20621067 miR-126:Alteration of processing induced by a single nucleotide polymorphism in pri-miR-126 genetics_GWAS hsa-mir-146a Gastrointestinal Neoplasms 20653068 Pre-miR-146a C/G polymorphism might be associated with an elevatedrisk of gastric cancer in Chinese population. genetics_GWAS hsa-mir-27a Gastric Neoplasms 20666778 mir-27a:mir-27a genetic variant contributes to gastric cancer susceptibility genetics_GWAS hsa-mir-146a Gastrointestinal Neoplasms 20721625 This study revealed the combined effect of miR-146a rs2910164 G/G and TLR4 +3725 C allele on the increased risk of severe gastric atrophy among the H. pylori-infected Japanese subjects. genetics_GWAS hsa-mir-155 Hypertension 20966899 "The interplay between miR-155 expression, +1166C polymorphism, and AT1R protein expression may have a role in the regulation of blood pressure." genetics_GWAS hsa-mir-146a Gastrointestinal Neoplasms 21073609 The rs2910164 (G>C) SNP in the miR-146a is associated with susceptibility to GC. genetics_GWAS hsa-mir-221 Melanoma 21119596 This KIT variant results in a mismatch in the seed region of a miR-221 complementary site and reporter data suggests that this mismatch can result in increased expression ofthe KIT oncogene. genetics_GWAS hsa-mir-491 Colorectal Carcinoma 21128281 deleted genetics_GWAS hsa-mir-646 Colorectal Carcinoma 21128281 deleted genetics_GWAS hsa-mir-17 Breast Neoplasms 21140207 SNP (rs3739008) located at 3'UTR of NPAS2 and the C to T changing of the SNP may disrupt the binding of microRNA- (miR-)17-5p and miR-519e to the 3'UTR of NPAS2 genetics_GWAS hsa-mir-519e Breast Neoplasms 21140207 SNP (rs3739008) located at 3'UTR of NPAS2 and the C to T changing of the SNP may disrupt the binding of microRNA- (miR-)17-5p and miR-519e to the 3'UTR of NPAS2 genetics_GWAS hsa-mir-569 Systemic Lupus Erythematosus 21162035 Association of a functional polymorphism in the 3' untranslated region of SPI1 with systemic lupus erythematosus. genetics_GWAS hsa-mir-196a-2 Colorectal Carcinoma 21241442 A variant ( rs11614913 ) in microRNA-196a2 is not associated with susceptibility to and progression of colorectal cancer in Chinese. genetics_GWAS hsa-mir-196a-1 Crohn Disease 21278745 The common exonic synonymous SNP (c.313C>T) in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. genetics_GWAS hsa-mir-196a-2 Crohn Disease 21278745 The common exonic synonymous SNP (c.313C>T) in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. genetics_GWAS hsa-mir-196b Crohn Disease 21278745 The common exonic synonymous SNP (c.313C>T) in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. genetics_GWAS hsa-mir-124-1 Breast Neoplasms 21318219 Genetic variants (SNP rs1042538 A/T) at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. genetics_GWAS hsa-mir-124-2 Breast Neoplasms 21318219 Genetic variants (SNP rs1042538 A/T) at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. genetics_GWAS hsa-mir-124-3 Breast Neoplasms 21318219 Genetic variants (SNP rs1042538 A/T) at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. genetics_GWAS hsa-mir-146a Esophageal Neoplasms 21319225 SNP (rs2910164 G/C): Significantly increased CSCC risks were found to be associated with G allele of rs2910164 genetics_GWAS hsa-mir-146a "Squamous Cell Carcinoma, Cerevial" 21319225 SNP (rs2910164 G/C): Significantly increased CSCC risks were found to be associated with G allele of rs2910164 genetics_GWAS hsa-mir-499a Esophageal Neoplasms 21319225 SNP (rs3746444 A/G): Significantly increased CSCC risks were found to be associated with G allele of rs3746444 genetics_GWAS hsa-mir-499a "Squamous Cell Carcinoma, Cerevial" 21319225 SNP (rs3746444 A/G): Significantly increased CSCC risks were found to be associated with G allele of rs3746444 genetics_GWAS hsa-mir-196a-2 Urinary Bladder Cancer 21345130 "Our results showed that the heterozygous genotype of rs11614913 (hsa-mir-196a2 C>T rs11614913) was higher in cases than controls but the results were marginally significant (p=0.055; odds ratio, 1.44)." genetics_GWAS hsa-mir-196b Urinary Bladder Cancer 21345130 "Our results showed that the heterozygous genotype of rs11614913 (hsa-mir-196a2 C>T rs11614913) was higher in cases than controls but the results were marginally significant (p=0.055; odds ratio, 1.44)." genetics_GWAS hsa-mir-569 Systemic Lupus Erythematosus 21360505 rs1057233 alters a target sequence for microRNA hsa-miR-569 (miR-569). genetics_GWAS hsa-mir-328 Myopia 21421876 "SNPs rs644242 and rs662702 had marginal significance (p=0.063) and further analyses showed that these SNPs were associated with extreme myopia. The OR for extreme myopia was 2.1 (empirical p=0.007) for the CC genotype at SNP rs662702 at 3' UTR. The functional assay for SNP rs662702 demonstrated that the C allele had a significantly lower expression level than the T allele (P=0.0001). SNP rs662702 was predicted to be located in the microRNA-328 binding site, which may explain the differential allelic effect on gene expression." genetics_GWAS hsa-let-7a-1 Ovarian Neoplasms 21482675 "rs12194974 (G>A), a SNP in a putative transcription factor binding site in the LIN28B promoter region (summary OR=0.90, 95% CI: 0.82-0.98; P=0.015). LIN28B LIN28B over-expression in epithelial ovarian cancer (EOC) contributes to tumorigenesis by repressing tumor suppressor let-7 expression." genetics_GWAS hsa-let-7a-2 Ovarian Neoplasms 21482675 "rs12194974 (G>A), a SNP in a putative transcription factor binding site in the LIN28B promoter region (summary OR=0.90, 95% CI: 0.82-0.98; P=0.015). LIN28B LIN28B over-expression in epithelial ovarian cancer (EOC) contributes to tumorigenesis by repressing tumor suppressor let-7 expression." genetics_GWAS hsa-let-7a-3 Ovarian Neoplasms 21482675 "rs12194974 (G>A), a SNP in a putative transcription factor binding site in the LIN28B promoter region (summary OR=0.90, 95% CI: 0.82-0.98; P=0.015). LIN28B LIN28B over-expression in epithelial ovarian cancer (EOC) contributes to tumorigenesis by repressing tumor suppressor let-7 expression." genetics_GWAS hsa-mir-196a-2 Breast Neoplasms 21483822 "rs11614913 polymorphism:Overall, individuals with the TC/CC genotypes were associated with higher cancer risk than those with the TT genotype (OR=1.18, 95% CI=1.03-1.34, P<0.001 for heterogeneity test). In the stratified analyses, we observed that the CC genotype might modulate breast cancer risk (OR=1.11, 95%CI=1.01-1.23, P(heterogeneity)=0.210) and lung cancer risk (OR=1.25, 95%CI=1.06-1.46, P(heterogeneity)=0.958), comparing with the TC/TT genotype. Moreover, a significantly increased risk was found among Asian populations in a dominant model (TC/CC versus TT, OR=1.24, 95% CI=1.07-1.43, P(heterogeneity)=0.006)." genetics_GWAS hsa-mir-196a-2 Lung Neoplasms 21483822 "rs11614913 polymorphism:Overall, individuals with the TC/CC genotypes were associated with higher cancer risk than those with the TT genotype (OR=1.18, 95% CI=1.03-1.34, P<0.001 for heterogeneity test). In the stratified analyses, we observed that the CC genotype might modulate breast cancer risk (OR=1.11, 95%CI=1.01-1.23, P(heterogeneity)=0.210) and lung cancer risk (OR=1.25, 95%CI=1.06-1.46, P(heterogeneity)=0.958), comparing with the TC/TT genotype. Moreover, a significantly increased risk was found among Asian populations in a dominant model (TC/CC versus TT, OR=1.24, 95% CI=1.07-1.43, P(heterogeneity)=0.006)." genetics_GWAS hsa-mir-146a "Tuberculosis, Pulmonary" 21524676 "A polymorphism (rs2910164 G>C, in miR-146a) indicated an association with PTB risk in both Tibetan (p = 0.031) and Han (p = 0.000) populations. However, the role of the G allele of rs2910164, like the C allele in rs3746444, differed in the Tibetan (OR = 1.509, p < 0.05) and Han (OR = 0.575, p < 0.05) groups." genetics_GWAS hsa-mir-499a "Tuberculosis, Pulmonary" 21524676 "There was no association between rs3746444 (in hsa-mir-499) and PTB risk (p = 0.118) in the Han population, but subjects carrying the C allele exhibited decreased PTB risk (odds ratio [OR] = 0.403 [95% confidence interval (95% CI) 0.278-0.583]). There was an association between rs3746444 and PTB in the Tibetan population, and individuals carrying the C allele exhibited increased PTB risk (OR = 1.870 [95% CI 1.218-2.871])." genetics_GWAS hsa-mir-146a Urinary Bladder Cancer 21529907 Polymorphism (rs2910164) of the pre-miR-146a is associated with risk of cervical cancer in a Chinese population. The subjects carrying GG homozygote had a 1.496-foldincreased risk than those carrying CG/CC genotypes. The carriers of GG genotype had obviously more reduced miR-146a expression level compared with the carriers of CC genotype. genetics_GWAS hsa-mir-137 Melanoma 21543894 miR-137 under expression was significantly associated with melanomas with the KRAS-variant. genetics_GWAS hsa-mir-125b-1 Prostate Neoplasms 21556765 rs1434536 in the 3'UTR of BMPR1B gene affects the binding ability of miR-125b to BMPR1B mRNA and contributes to the genetic hspredisposition to localized prostate cancer and patients aged >70years. genetics_GWAS hsa-mir-125b-2 Prostate Neoplasms 21556765 rs1434536 in the 3'UTR of BMPR1B gene affects the binding ability of miR-125b to BMPR1B mRNA and contributes to the genetic hspredisposition to localized prostate cancer and patients aged >70years. genetics_GWAS hsa-mir-637 Hypertension 21558123 A common genetic variant (rs938671) in the 3'-UTR of Vacuolar H+-ATPase ATP6V0A1 creates a micro-RNA (hsa-miR-637) motif to alter Chromogranin A (CHGA) processing and hypertension risk. genetics_GWAS hsa-mir-519a-1 Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-519a-2 Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-519b Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-519c Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-519d Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-519e Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-520a Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-520b Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-520d Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-520e Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-520f Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-520g Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-520h Gout 21558165 There was a clear link between the rs1333049 genotypic and allelic frequencies between gout cases and controls. There was a significantly increased risk of gout in carriers of the CC genotype.This SNP is homologous to miR-519 and miR-520. genetics_GWAS hsa-mir-196a-2 Chronic Obstructive Pulmonary Disease 21565178 "The TT genotype and T allele of miR-196a2 rs11614913 were significantly associated with a decreased risk for COPD (Chronic obstructive pulmonary disease), compared with the CC genotype and C allele. Similarly, the GG genotype and G allele of miR-499 rs3746444 were associated with a decreased risk for COPD, compared with the AA genotype and A allele." genetics_GWAS hsa-mir-499a Chronic Obstructive Pulmonary Disease 21565178 "The TT genotype and T allele of miR-196a2 rs11614913 were significantly associated with a decreased risk for COPD (Chronic obstructive pulmonary disease), compared with the CC genotype and C allele. Similarly, the GG genotype and G allele of miR-499 rs3746444 were associated with a decreased risk for COPD, compared with the AA genotype and A allele." genetics_GWAS hsa-mir-196a-2 Colorectal Carcinoma 21565628 A Functional Variant in MicroRNA-196a2 (rs11614913 SNP) Is Associated with Susceptibility of Colorectal Cancer in a Chinese Population. genetics_GWAS hsa-mir-1302-1 Male Infertility 21601192 "Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro." genetics_GWAS hsa-mir-1302-2 Male Infertility 21601192 "Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro." genetics_GWAS hsa-mir-1302-3 Male Infertility 21601192 "Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro." genetics_GWAS hsa-mir-1302-4 Male Infertility 21601192 "Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro." genetics_GWAS hsa-mir-1302-5 Male Infertility 21601192 "Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro." genetics_GWAS hsa-mir-1302-6 Male Infertility 21601192 "Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro." genetics_GWAS hsa-mir-1302-7 Male Infertility 21601192 "Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro." genetics_GWAS hsa-mir-1302-8 Male Infertility 21601192 "Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 and overexpression of CGA in vitro." genetics_GWAS hsa-mir-196a-2 Hepatitis C Virus Infection 21604580 SNP rs11614913 on miR196a-2 gene is associated with the antiviral therapy efficacy of hepatitis C patients.The TT genotype or T alleles be associated with the SVR while the CC genotype or C allele could be related to the NVR or recurrence. genetics_GWAS hsa-mir-196a-2 "Carcinoma, Lung, Non-Small-Cell" 21617338 MicroRNA196a2 rs11614913 Genotypes are associated with the Risk of Non-Small Cell Lung Cancer in Korean Population. genetics_GWAS hsa-mir-146a Gastric Neoplasms 21632853 "miR-146a levels in cancer tissues were significantly lower than those in the corresponding noncancerous tissue. Lower levels of miR-146a were associated with lymph node metastasis and venous invasion. Moreover, a lower level of miR-146a was an independent prognostic factor for overall survival.Ectopic expression of miR-146a inhibited migration and invasion and downregulated EGFR and IRAK1 expression in gastric cancer cells. In addition, G/C SNP within the pre-miR-146a seed sequence significantly reduced miR-146a levels in the GG genotype compared with the CC genotype." genetics_GWAS hsa-mir-492 Psoriasis 21655935 "The rs8259 T allele was associated with significantly decreased psoriasis susceptibility (OR=0.758, 95% CI 0.638-0.901, p=0.002) compared to A allele. the rs8259 polymorphism was located in a seed region for miR-492 binding." genetics_GWAS hsa-mir-1827 "Carcinoma, Lung, Small-Cell" 21676885 "Genetic Variation in an miRNA-1827 Binding Site in MYCL1 Alters Susceptibility to Small-Cell Lung Cancer. The rs3134615T allele was associated with a significantly increased risk of SCLC, with the OR for carrying the GT or TT genotype being 2.08 (95% confidence interval, 1.39-3.21; P = 0.0004) compared with the GG genotype." genetics_GWAS hsa-mir-146a Systemic Lupus Erythematosus 21738483 A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus. genetics_GWAS hsa-mir-146a Glioblastoma 21744077 "A functional polymorphism in the pre-miR-146a gene is associated with risk and prognosis in adult glioma. An increased glioma risk was observed among rs2910164 minor allele (C) carriers (per allele OR (95%CI)=1.22 (1.01-1.46, p (trend)=0.039)). The association was stronger among older subjects carrying at least one copy of the C allele (OR (95% CI)=1.38 (1.04-1.83, P=0.026). Mortality was increased among minor allele carriers (HR(95% CI)=1.33 (1.03-1.72, P=0.029)), with the association largely restricted to females (HR (95% CI)=2.02 (1.28-3.17, P=0.002))." genetics_GWAS hsa-mir-101 "Carcinoma, Ovarian" 21765906 "a few of which have been found in the genomic fragile regions that are associated with abnormal deletion or amplification in cancer, such as miR-21, miR-101-1, miR-210 and miR-301a." genetics_GWAS hsa-mir-21 "Carcinoma, Ovarian" 21765906 "a few of which have been found in the genomic fragile regions that are associated with abnormal deletion or amplification in cancer, such as miR-21, miR-101-1, miR-210 and miR-301a." genetics_GWAS hsa-mir-210 "Carcinoma, Ovarian" 21765906 "a few of which have been found in the genomic fragile regions that are associated with abnormal deletion or amplification in cancer, such as miR-21, miR-101-1, miR-210 and miR-301a." genetics_GWAS hsa-mir-301a "Carcinoma, Ovarian" 21765906 "a few of which have been found in the genomic fragile regions that are associated with abnormal deletion or amplification in cancer, such as miR-21, miR-101-1, miR-210 and miR-301a." genetics_GWAS hsa-mir-155 Hypertrophy 21771600 the C allele of rs5186 was associated with a significant increase in SWT (p=0.003) and LVM (p=0.001). This functional polymorphism increases expression of AGTR1 by altering the binding site for miR-155 genetics_GWAS hsa-mir-125a Habitual Abortion 21788734 "Two common SNPs (rs41275794, rs12976445) in pri-miR-125a alter the mature miRNA expression and associate with Abortion, Habitual in a Han-Chinese population." genetics_GWAS hsa-mir-367 Breast Neoplasms 21810988 "Functional SNP (rs1044129, is present in binding region) in the microRNA-367 binding site in the 3'UTR of the calcium channel ryanodine receptor gene 3 (RYR3) affects breast cancer risk and calcification." genetics_GWAS hsa-mir-196a-2 Colorectal Carcinoma 21815818 A Functional Polymorphism (rs11614913 (T>C)) in miRNA-196a2 Is Associated with Colorectal Cancer Risk in a Chinese Population. genetics_GWAS hsa-mir-542 Colorectal Carcinoma 21822307 A common single-nucleotide polymorphism (T8473CA) in cyclooxygenase-2 disrupts microRNA (miR-542-3p)-mediated regulation. genetics_GWAS hsa-mir-637 Hypertension 21846868 ATP6V0A1 Polymorphism and MicroRNA-637 may have A Pathogenetic Role for MicroRNAs in Essential Hypertension. genetics_GWAS hsa-mir-146a "Carcinoma, Lung, Non-Small-Cell" 21902575 CG genotype of miR-146a(rs2910164 C-G) appeared associated to an increased risk for NSCLC (p=0.042 and 1.77 OR). genetics_GWAS hsa-mir-146b "Carcinoma, Lung, Non-Small-Cell" 21902575 CG genotype of miR-146a(rs2910164 C-G) appeared associated to an increased risk for NSCLC (p=0.042 and 1.77 OR). genetics_GWAS hsa-mir-196a-2 "Carcinoma, Lung, Non-Small-Cell" 21902575 "The authors clearly detected a significant increase (p<0.001) of miR-196a2 expression in NSCLC. In particular the authors found a significant association between miR-196a2 (rs11614913 C-T) CC genotype and high expression, whereas TT genotype showed a very low expression in comparison to both CT (p<0.005) and CC patients (p<0.01)." genetics_GWAS hsa-mir-137 Schizophrenia 21926974 "GWAS analysis revealed that rs1625579 within an intron of a putative primary transcript for MIR137 (microRNA 137), a known regulator of neuronal development was associated with schizophrenia." genetics_GWAS hsa-mir-184 "Squamous Cell Carcinoma, Head and Neck" 21934093 "The authors found that, compared with the rs8126 TT (a SNP of miR-184 Binding Site in TNFAIP2) genotype, the variant C allele were associated with increased SCCHN risk in an allele-dose response manner (adjusted odds ratio=1.48 and 95% confidence interval=1.06-2.05 for CC, respectively; P(trend)=0.009)." genetics_GWAS hsa-mir-149 Gastric Neoplasms 21976437 "Marginally significant associations were found both for hsa-miR-149 rs2292832 with gastric cancer risk (TC+CC vs. TT, OR=0.68, 95% CI: 0.44-1.04) and for hsa-miR-605 rs2043556 with colorectal cancer risk (AG+GG vs. AA, OR=0.70, 95% CI: 0.48-1.02) in males." genetics_GWAS hsa-mir-605 Gastric Neoplasms 21976437 "Marginally significant associations were found both for hsa-miR-149 rs2292832 with gastric cancer risk (TC+CC vs. TT, OR=0.68, 95% CI: 0.44-1.04) and for hsa-miR-605 rs2043556 with colorectal cancer risk (AG+GG vs. AA, OR=0.70, 95% CI: 0.48-1.02) in males." genetics_GWAS hsa-mir-146a Thyroid Neoplasms 21978540 "Despite some limitations, this meta-analysis suggests that the miR-146a G allele is a low-penetrant risk factor for papillary thyroid carcinoma development." genetics_GWAS hsa-mir-218-1 "Carcinoma, Hepatocellular" 22011248 "The AG genotype of pri-miR-218 rs11134527 A/G was associated with family history (p=0.018, odds ratio [OR]=2.96, 95% confidence interval [CI]: 1.16-7.56) and elevated serum alpha-fetoprotein (serum alpha-fetoprotein [AFP]) levels (¡Ý20 ng/mL; p=0.009, OR=1.92, 95% CI: 1.17-3.14) in HCC patients. These findings suggested that the AG genotype of pri-miR-218 rs11134527 might relate to genetic predisposition and be involved in regulating the expression of AFP in Chinese HCC patients." genetics_GWAS hsa-mir-218-2 "Carcinoma, Hepatocellular" 22011248 "The AG genotype of pri-miR-218 rs11134527 A/G was associated with family history (p=0.018, odds ratio [OR]=2.96, 95% confidence interval [CI]: 1.16-7.56) and elevated serum alpha-fetoprotein (serum alpha-fetoprotein [AFP]) levels (¡Ý20 ng/mL; p=0.009, OR=1.92, 95% CI: 1.17-3.14) in HCC patients. These findings suggested that the AG genotype of pri-miR-218 rs11134527 might relate to genetic predisposition and be involved in regulating the expression of AFP in Chinese HCC patients." genetics_GWAS hsa-mir-499a Rheumatoid Arthritis 22019503 "There was a significant difference in the levels of CRP and ESR among different genotypes in rs3746444 (hsa-mir-499) (p = 0.031 and p = 0.047, respectively) in Chinese Han people. The heterozygote CT had significantly higher levels of CRP and ESR compared with homozygotes CC and TT." genetics_GWAS hsa-mir-423 Colorectal Carcinoma 22028396 "Two SNPs were identified to be significantly associated with recurrence-free survival and overall survival of the patients. The most significant SNP was rs6505162 in pre-miR-423. Compared to the homozygous wild-type genotype, the variant-containing genotypes of this SNP were significantly associated with both the overall survival (HR=2.12, 95% CI1.34--3.34, P=0.001) and the recurrence-free survival (HR=1.59, 95% CI1.08--2.36, P=0.019). Another SNP, rs4919510 in pre-miR-608, was also associated with altered recurrence-free survival (HR=0.61, 95% CI 0.41-0.92, P=0.017). These effects were evident only in patients receiving chemotherapy but not in those without chemotherapy. In addition, the combined analysis of the two SNPs conferred a 2.84-fold (95% CI 1.50-5.37, P=0.001) increased risk of recurrence and/or death. Similarly, this effect was only prominent in those receiving chemotherapy (P<0.001) but not in those without chemotherapy (P=0.999)." genetics_GWAS hsa-mir-608 Colorectal Carcinoma 22028396 "Two SNPs were identified to be significantly associated with recurrence-free survival and overall survival of the patients. The most significant SNP was rs6505162 in pre-miR-423. Compared to the homozygous wild-type genotype, the variant-containing genotypes of this SNP were significantly associated with both the overall survival (HR=2.12, 95% CI1.34--3.34, P=0.001) and the recurrence-free survival (HR=1.59, 95% CI1.08--2.36, P=0.019). Another SNP, rs4919510 in pre-miR-608, was also associated with altered recurrence-free survival (HR=0.61, 95% CI 0.41-0.92, P=0.017). These effects were evident only in patients receiving chemotherapy but not in those without chemotherapy. In addition, the combined analysis of the two SNPs conferred a 2.84-fold (95% CI 1.50-5.37, P=0.001) increased risk of recurrence and/or death. Similarly, this effect was only prominent in those receiving chemotherapy (P<0.001) but not in those without chemotherapy (P=0.999)." genetics_GWAS hsa-mir-196a-2 Breast Neoplasms 22074121 "The Chinese women with menarche age less than 16 years had increased breast cancer risk (OR = 2.10, 95% CI: 1.23-3.60). Marginally significant association between rs11614913 (hsa-miR-196a-2) CT/CC genotypes and reduced breast cancer risk was observed (OR = 0.65, 95% CI: 0.40-1.06)," genetics_GWAS hsa-mir-502 "Carcinoma, Hepatocellular" 22095217 "We analysed a single nucleotide polymorphism (rs16917496) within the miR-502 microRNA seed region for the 3' UTR of SET8 in Chinese hepatocellular carcinoma (HCC) patients. The SET8 CC genotype was independently associated with longer post-operative survival in HCC patients by multivariate analysis (relative risk, 0.175; 95% CI, 0.053 - 0.577; p = 0.004). The SET8 CC genotype was associated with reduced SET8 protein levels based on the immunostaining of 51 HCC tissue samples. We also found the low SET8 levels was associated with longer HCC survival. Our data suggest that SET8 modifies HCC outcome by altering its expression, which depends, at least in part, on its binding affinity with miR502." genetics_GWAS hsa-mir-30c-1 Gastric Neoplasms 22108846 "The genotype frequencies of pre-miR-30c A/G (Polymorphism rs928508 in pre-miR-30c) in gastric cancer patients were obviously different from those in the controls (P = 0.022). AA genotype carriers were associated with an increased risk of gastric cancer compared with GG genotype (adjusted odds ratio (OR) = 1.83, 95% confidence interval (CI): 1.07-3.15, P = 0.029). Moreover, the gastric cancer risk especially elevated in older individuals (aged >60 years), males, nonsmokers, and Helicobacter pylori (H. pylori)-infected individuals (adjusted OR = 2.66, 95% CI: 1.38-5.13, P = 0.004; adjusted OR = 1.90, 95% CI: 1.10-3.27, P = 0.022; adjusted OR = 1.94, 95% CI: 1.12-3.35, P = 0.018; adjusted OR = 1.83, 95% CI: 1.08-3.10, P = 0.024, respectively). Further stratified analysis indicated that AA genotype facilitated developing of gastric cancer with lymph node metastasis (adjusted OR = 2.23, 95% CI: 1.07-4.64, P = 0.032). Expression analysis detected that rs928508 AA showed a significantly increased level of mature miR-30c compared with GG or AG/GG genotype (P = 0.011 or P = 0.013). Patients with AA genotype were associated with unfavorable outcome in overall survival compared with AG/GG genotype (Log rank 5.848, P = 0.016). This study demonstrates that pre-miR-30c A/G polymorphism may be associated with an increased risk of gastric cancer in a Chinese population through altering mature miR-30c expression." genetics_GWAS hsa-mir-30c-2 Gastric Neoplasms 22108846 "The genotype frequencies of pre-miR-30c A/G (Polymorphism rs928508 in pre-miR-30c) in gastric cancer patients were obviously different from those in the controls (P = 0.022). AA genotype carriers were associated with an increased risk of gastric cancer compared with GG genotype (adjusted odds ratio (OR) = 1.83, 95% confidence interval (CI): 1.07-3.15, P = 0.029). Moreover, the gastric cancer risk especially elevated in older individuals (aged >60 years), males, nonsmokers, and Helicobacter pylori (H. pylori)-infected individuals (adjusted OR = 2.66, 95% CI: 1.38-5.13, P = 0.004; adjusted OR = 1.90, 95% CI: 1.10-3.27, P = 0.022; adjusted OR = 1.94, 95% CI: 1.12-3.35, P = 0.018; adjusted OR = 1.83, 95% CI: 1.08-3.10, P = 0.024, respectively). Further stratified analysis indicated that AA genotype facilitated developing of gastric cancer with lymph node metastasis (adjusted OR = 2.23, 95% CI: 1.07-4.64, P = 0.032). Expression analysis detected that rs928508 AA showed a significantly increased level of mature miR-30c compared with GG or AG/GG genotype (P = 0.011 or P = 0.013). Patients with AA genotype were associated with unfavorable outcome in overall survival compared with AG/GG genotype (Log rank 5.848, P = 0.016). This study demonstrates that pre-miR-30c A/G polymorphism may be associated with an increased risk of gastric cancer in a Chinese population through altering mature miR-30c expression." genetics_GWAS hsa-mir-629 Lung Neoplasms 22114071 "The rs2735383CC (NBS1 gene) genotype had a significantly increased risk of lung cancer under a recessive genetic model in the total 1559 cases versus 1679 controls (OR = 1.40, 95% C.I. = 1.18-1.66, P = 0.0001) when compared with GG or GC genotypes; the rs2735383CC genotype carriers had lower mRNA and protein expression levels in tumor tissues than those of other genotypes as qPCR and western blot shown. Luciferase assay revealed that the rs2735383C allele had a lower transcription activity than G allele; and the hsa-miR-629 but not hsa-miR-499-5P had effect on modulation of NBS1 gene in vitro. We further observed that the X-ray radiation induced more chromatid breaks in lymphocyte cells from the carriers of rs2735383CC homozygote than those from the subjects with other genotypes (P = 0.0008). Our data suggested that the rs2735383G>C variation contributes to an increased risk of lung cancer by diminishing gene's expression through binding of microRNA-629 to the polymorphic site in the 3'-UTR of NBS1 gene." genetics_GWAS hsa-mir-196a-2 Coronary Artery Disease 22159951 "The variant genotypes CC/CT of hsa-mir-196a2 rs11614913 T ¡ú C were not associated with a significantly increased risk of CAD (adjusted OR = 1.02, 95% CI = 0.76-1.38), compared with wide genotype TT, but CC and CC/CT genotypes were associated with 34 and 35% increased risks of serious prognosis of CAD (adjusted HR = 1.34, 95% CI = 1.02-1.75 for CC; adjusted HR = 1.35, 95% CI = 1.03-1.75 for CC/CT). In the variant of hsa-mir-499 rs3746444A ¡ú G, GG was associated with the 223% increased risk of CAD (adjusted OR = 3.23, 95% CI = 1.56-6.67). Cox regression analysis showed that age, smoking status, numbers of pathological changes in coronary arteries, rs11614913 T ¡ú C, and diabetes mellitus were associated with serious prognosis of CAD." genetics_GWAS hsa-mir-499a Coronary Artery Disease 22159951 "The variant genotypes CC/CT of hsa-mir-196a2 rs11614913 T ¡ú C were not associated with a significantly increased risk of CAD (adjusted OR = 1.02, 95% CI = 0.76-1.38), compared with wide genotype TT, but CC and CC/CT genotypes were associated with 34 and 35% increased risks of serious prognosis of CAD (adjusted HR = 1.34, 95% CI = 1.02-1.75 for CC; adjusted HR = 1.35, 95% CI = 1.03-1.75 for CC/CT). In the variant of hsa-mir-499 rs3746444A ¡ú G, GG was associated with the 223% increased risk of CAD (adjusted OR = 3.23, 95% CI = 1.56-6.67). Cox regression analysis showed that age, smoking status, numbers of pathological changes in coronary arteries, rs11614913 T ¡ú C, and diabetes mellitus were associated with serious prognosis of CAD." genetics_GWAS hsa-mir-196a-2 Colorectal Carcinoma 22161766 The authors found a significantly increased colorectal cancer risk with the miR-196a2CC (rs11614913) genotype compared with the TT/CT genotype (AOR=1.50; 95% CI=1.11-2.04; P=0.01; FDR-P=0.04) in Korean population. genetics_GWAS hsa-mir-146a "Squamous Cell Carcinoma, Oral" 22182931 "This study identifies that areca nut extract, TNFalpha and TGFbeta up-regulates miR-146a in OSCC cells. The increased expression of miR-146a enhanced the oncogenicity of OSCC cells. In addition, a G to C polymorphism (rs2910164), which is located in the pre-miR-146a and has been associated with functional alterations in miR-146a, was significantly more prevalent among OSCC patients having more advanced nodal involvement. Our analysis also suggested a higher miR-146a expression in OSCC tissues of patients carrying C polymorphism. The present study concluded a higher prevalence of the pre-mir-146a C-variant was associated with OSCC progression in patients with this disease." genetics_GWAS hsa-mir-570 Gastric Neoplasms 22190470 A guanine-to-cytosine mutation at the 3'-UTR of CD274 mRNA led to CD274 over-expression by disrupting the miR-570 binding. A frequent somatic mutation in CD274 3'-UTR leads to protein over-expression in gastric cancer by disrupting miR-570 binding. genetics_GWAS hsa-mir-200b Endometrial Neoplasms 22194984 Luciferase assays and Western blot analysis demonstrated that the miR-200b/200c/429 family recognized the MRE in the 3' UTR of AP-2alpha gene and negatively regulated the expression of endogenous AP-2alpha proteins. SNP rs1045385 A>C variation enhanced AP-2alpha. genetics_GWAS hsa-mir-200c Endometrial Neoplasms 22194984 Luciferase assays and Western blot analysis demonstrated that the miR-200b/200c/429 family recognized the MRE in the 3' UTR of AP-2 alpha gene and negatively regulated the expression of endogenous AP-2 alpha proteins. SNP rs1045385 A>C variation enhanced AP-2 alpha expression. genetics_GWAS hsa-mir-429 Endometrial Neoplasms 22194984 Luciferase assays and Western blot analysis demonstrated that the miR-200b/200c/429 family recognized the MRE in the 3' UTR of AP-2 alpha gene and negatively regulated the expression of endogenous AP-2 alpha proteins. SNP rs1045385 A>C variation enhanced AP-2 alpha expression. genetics_GWAS hsa-mir-146a Systemic Lupus Erythematosus 22218224 "The SNP (rs2431697) was associated with the microRNA-146a, where the risk allele correlates with lower expression of the miRNA." genetics_GWAS hsa-mir-196a-2 Habitual Abortion 22222140 "RSA(recurrent spontaneous abortion) patients exhibited significantly different frequencies of the miR-196a2CC (TT+TC vs. CC; adjusted odds ratio [AOR], 1.587; 95% confidence interval [CI], 1.042-2.417) and miR-499AG+GG genotypes (AOR, 1.671; 95% CI, 1.054-2.651) compared with the control group." genetics_GWAS hsa-mir-499a Habitual Abortion 22222140 "RSA(recurrent spontaneous abortion) patients exhibited significantly different frequencies of the miR-196a2CC (TT+TC vs. CC; adjusted odds ratio [AOR], 1.587; 95% confidence interval [CI], 1.042-2.417) and miR-499AG+GG genotypes (AOR, 1.671; 95% CI, 1.054-2.651) compared with the control group." genetics_GWAS hsa-mir-17 Ovarian Neoplasms 22235027 "The most notable cluster is the tumorigenic miR-17-92 cluster with five microRNAs, all of which are significantly associated with rs3814113" genetics_GWAS hsa-mir-18a Ovarian Neoplasms 22235027 "The most notable cluster is the tumorigenic miR-17-92 cluster with five microRNAs, all of which are significantly associated with rs3814113" genetics_GWAS hsa-mir-19a Ovarian Neoplasms 22235027 "The most notable cluster is the tumorigenic miR-17-92 cluster with five microRNAs, all of which are significantly associated with rs3814113" genetics_GWAS hsa-mir-19b-1 Ovarian Neoplasms 22235027 "The most notable cluster is the tumorigenic miR-17-92 cluster with five microRNAs, all of which are significantly associated with rs3814113" genetics_GWAS hsa-mir-20a Ovarian Neoplasms 22235027 "The most notable cluster is the tumorigenic miR-17-92 cluster with five microRNAs, all of which are significantly associated with rs3814113" genetics_GWAS hsa-mir-92a-1 Ovarian Neoplasms 22235027 "The most notable cluster is the tumorigenic miR-17-92 cluster with five microRNAs, all of which are significantly associated with rs3814113" genetics_GWAS hsa-let-7e Crohn Disease 22262659 The rs10889677 variant in the 3'-untranslated region of the IL-23R gene displays enhanced levels of both mRNA and protein production of IL-23R. This can be attributed to a loss of binding capacity for the microRNAs (miRNAs) Let-7e and Let-7f by the variant allele. genetics_GWAS hsa-let-7f-1 Crohn Disease 22262659 The rs10889677 variant in the 3'-untranslated region of the IL-23R gene displays enhanced levels of both mRNA and protein production of IL-23R. This can be attributed to a loss of binding capacity for the microRNAs (miRNAs) Let-7e and Let-7f by the variant allele. genetics_GWAS hsa-let-7f-2 Crohn Disease 22262659 The rs10889677 variant in the 3'-untranslated region of the IL-23R gene displays enhanced levels of both mRNA and protein production of IL-23R. This can be attributed to a loss of binding capacity for the microRNAs (miRNAs) Let-7e and Let-7f by the variant allele. genetics_GWAS hsa-let-7a-1 Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. genetics_GWAS hsa-let-7a-2 Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. genetics_GWAS hsa-let-7a-3 Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. genetics_GWAS hsa-let-7b Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. genetics_GWAS hsa-let-7c Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. genetics_GWAS hsa-let-7d Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. genetics_GWAS hsa-let-7e Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. genetics_GWAS hsa-let-7f-1 Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. genetics_GWAS hsa-let-7f-2 Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. genetics_GWAS hsa-let-7g Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. genetics_GWAS hsa-let-7i Endometriosis 22307873 The authors detected a KRAS variant allele in 31% of women with endometriosis as opposed to 5% of a large diverse control population. genetics_GWAS hsa-mir-1207 Glomerulonephritis 22319602 "A miR-1207-5p binding site polymorphism (C1936T, rs13385) abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy." genetics_GWAS hsa-mir-155 "Lymphoma, Non-Hodgkin" 22347493 "Variant rs928883, near miR-155, showed an association (OR per A-allele: 2.80 [95% CI: 1.63-4.82]; p(F)=0.027) with marginal zone lymphoma that is significant after correction for multiple testing." genetics_GWAS hsa-mir-1273c Colorectal Carcinoma 22348132 "hsa-mir-1273c, hsa-mir-1303 and hsa-mir-567, with frequent and sometimes bi-allelic mutations in MSI tumors." genetics_GWAS hsa-mir-1303 Colorectal Carcinoma 22348132 "hsa-mir-1273c, hsa-mir-1303 and hsa-mir-567, with frequent and sometimes bi-allelic mutations in MSI tumors." genetics_GWAS hsa-mir-567 Colorectal Carcinoma 22348132 "hsa-mir-1273c, hsa-mir-1303 and hsa-mir-567, with frequent and sometimes bi-allelic mutations in MSI tumors." genetics_GWAS hsa-mir-25 Lung Neoplasms 22349819 REV3L 3'UTR 460 T>C polymorphism in microRNA(miR-25/32) target sites contributes to lung cancer susceptibility. genetics_GWAS hsa-mir-32 Lung Neoplasms 22349819 REV3L 3'UTR 460 T>C polymorphism in microRNA(miR-25/32) target sites contributes to lung cancer susceptibility. genetics_GWAS hsa-mir-27a Gastric Neoplasms 22350505 The SNP rs895819 in the miR-27a gene with the minor allele C presented significantly reduced risk to gastric cancer in Chinese population. genetics_GWAS hsa-mir-146a Breast Neoplasms 22363415 "The authors found that hs-miR-196a2 in premenopausal patients, and hs-miR-499, hs-miR-146a and hs-miR-196a2 in postmenopausal patients, may discriminate breast cancer patients from healthy individuals. In addition, we found a significant association between two microRNA polymorphisms (hs-miR-196a2 and hs-miR-499) and breast cancer risk." genetics_GWAS hsa-mir-196a-2 Breast Neoplasms 22363415 "The authors found that hs-miR-196a2 in premenopausal patients, and hs-miR-499, hs-miR-146a and hs-miR-196a2 in postmenopausal patients, may discriminate breast cancer patients from healthy individuals. In addition, we found a significant association between two microRNA polymorphisms (hs-miR-196a2 and hs-miR-499) and breast cancer risk." genetics_GWAS hsa-mir-499a Breast Neoplasms 22363415 "The authors found that hs-miR-196a2 in premenopausal patients, and hs-miR-499, hs-miR-146a and hs-miR-196a2 in postmenopausal patients, may discriminate breast cancer patients from healthy individuals. In addition, we found a significant association between two microRNA polymorphisms (hs-miR-196a2 and hs-miR-499) and breast cancer risk." genetics_GWAS hsa-mir-146a Breast Neoplasms 22363684 Increased Risk of Breast Cancer Associated with CC Genotype of Has-miR-146a Rs2910164 Polymorphism in Europeans. genetics_GWAS hsa-mir-499a Heart Failure 22374132 A naturally occurring miR-499 mutation(u17c in the 3' end) outside the critical seed sequence modifies mRNA targeting and end-organ function. genetics_GWAS hsa-mir-106b "Carcinoma, Hepatocellular" 22393390 "A Genetic Variant (rs999885) in the Promoter Region of miR-106b-25 Cluster and Risk of HBV Infection and Hepatocellular Carcinoma.Compared with the HBV natural clearance subjects carrying rs999885 AA genotype, those with AG/GG genotypes had a decreased risk of chronic HBV infection with an adjusted odds ratio (OR) of 0.79 [95% confidence intervals (CIs)=0.67-0.93]. However, the AG/GG genotypes were significantly associated with an increased HCC risk in HBV persistent carriers (adjusted OR=1.25, 95% CIs=1.06-1.47). Expression analysis revealed that the expression level of miR-106b-25 cluster was significantly higher in AG/GG carriers than those in AA carriers in non-tumor liver tissues." genetics_GWAS hsa-mir-106b Hepatitis B Virus Infection 22393390 "A Genetic Variant (rs999885) in the Promoter Region of miR-106b-25 Cluster and Risk of HBV Infection and Hepatocellular Carcinoma.Compared with the HBV natural clearance subjects carrying rs999885 AA genotype, those with AG/GG genotypes had a decreased risk of chronic HBV infection with an adjusted odds ratio (OR) of 0.79 [95% confidence intervals (CIs)=0.67-0.93]. However, the AG/GG genotypes were significantly associated with an increased HCC risk in HBV persistent carriers (adjusted OR=1.25, 95% CIs=1.06-1.47). Expression analysis revealed that the expression level of miR-106b-25 cluster was significantly higher in AG/GG carriers than those in AA carriers in non-tumor liver tissues." genetics_GWAS hsa-mir-25 "Carcinoma, Hepatocellular" 22393390 "A Genetic Variant (rs999885) in the Promoter Region of miR-106b-25 Cluster and Risk of HBV Infection and Hepatocellular Carcinoma.Compared with the HBV natural clearance subjects carrying rs999885 AA genotype, those with AG/GG genotypes had a decreased risk of chronic HBV infection with an adjusted odds ratio (OR) of 0.79 [95% confidence intervals (CIs)=0.67-0.93]. However, the AG/GG genotypes were significantly associated with an increased HCC risk in HBV persistent carriers (adjusted OR=1.25, 95% CIs=1.06-1.47). Expression analysis revealed that the expression level of miR-106b-25 cluster was significantly higher in AG/GG carriers than those in AA carriers in non-tumor liver tissues." genetics_GWAS hsa-mir-25 Hepatitis B Virus Infection 22393390 "A Genetic Variant (rs999885) in the Promoter Region of miR-106b-25 Cluster and Risk of HBV Infection and Hepatocellular Carcinoma.Compared with the HBV natural clearance subjects carrying rs999885 AA genotype, those with AG/GG genotypes had a decreased risk of chronic HBV infection with an adjusted odds ratio (OR) of 0.79 [95% confidence intervals (CIs)=0.67-0.93]. However, the AG/GG genotypes were significantly associated with an increased HCC risk in HBV persistent carriers (adjusted OR=1.25, 95% CIs=1.06-1.47). Expression analysis revealed that the expression level of miR-106b-25 cluster was significantly higher in AG/GG carriers than those in AA carriers in non-tumor liver tissues." genetics_GWAS hsa-mir-325 Dyspepsia 22438098 "Genetic polymorphism ( rs5981521 (C>T)) of pri-microRNA 325, targeting SLC6A4 3'-UTR, is closely associated with the risk of functional dyspepsia in Japan." genetics_GWAS hsa-mir-146a Gastric Neoplasms 22455393 A Functional Polymorphism (rs2910164) in Pre-miR-146a Is Associated with Susceptibility to Gastric Cancer in a Chinese Population. genetics_GWAS hsa-mir-938 Gastric Neoplasms 22537748 "Genetic polymorphisms of IL17A ((rs2275913 (-197 G > A), rs3748067 (*1249 C > T)) and pri-microRNA-938 (pri-miR-938, rs2505901 (T > C).), targeting IL17A 3'-UTR, influence susceptibility to gastric cancer." genetics_GWAS hsa-mir-520a Colorectal Carcinoma 22553375 A 3' untranslated region (UTR) mutation was also shown to be associated with increased sensitivity to saracatinib and have a reduced affinity for miR-520a and miR-525a. genetics_GWAS hsa-mir-608 Breast Neoplasms 22586447 Polymorphism rs4919510:C>G in mature sequence of human microRNA-608 contributes to the risk of HER2-positive breast cancer but not other subtypes. genetics_GWAS hsa-mir-423 Breast Neoplasms 22593246 A genetic variant (rs6505162:A>C) located in miR-423 is associated with reduced breast cancer risk. genetics_GWAS hsa-mir-608 Colorectal Carcinoma 22606253 rs4919510 in hsa-mir-608 is associated with outcome but not risk of colorectal cancer. genetics_GWAS hsa-mir-146a Moyamoya Disease 22659075 "Association of the miR-146aC>G, miR-196a2C>T, and miR-499A>G polymorphisms with moyamoya disease in the Korean population." genetics_GWAS hsa-mir-196a-2 Moyamoya Disease 22659075 "Association of the miR-146aC>G, miR-196a2C>T, and miR-499A>G polymorphisms with moyamoya disease in the Korean population." genetics_GWAS hsa-mir-219-1 Colorectal Carcinoma 22661538 "The mir219-1:rs213210 showed consistent association with death in the training set, the replication set, and combined data set" genetics_GWAS hsa-mir-608 Colorectal Carcinoma 22661538 "In patients with stage III disease, mir608: rs4919510 was associated with increased risk for both recurrence and death." genetics_GWAS hsa-mir-146a Nasopharyngeal Neoplasms 22711332 A single nucleotide polymorphism (rs2910164) in microRNA-146a is associated with the risk for nasopharyngeal carcinoma. genetics_GWAS hsa-mir-182 Melanoma 22752337 Up-regulation of miR-182 expression after epigenetic modulation of human melanoma cells. genetics_GWAS hsa-mir-499a "Squamous Cell Carcinoma, Oral" 22761899 "This study determined that a significant association of miRNA499 with CC genotype, as compared to the subjects with TT genotype, had a higher risk of oral squamous cell carcinoma." genetics_GWAS hsa-mir-499b "Squamous Cell Carcinoma, Oral" 22761899 "This study determined that a significant association of miRNA499 with CC genotype, as compared to the subjects with TT genotype, had a higher risk of oral squamous cell carcinoma." genetics_GWAS hsa-mir-7-1 Urinary Bladder Cancer 22768238 A microRNA-7 binding site polymorphism (1010A/G) in HOXB5 leads to differential gene expression in bladder cancer. genetics_GWAS hsa-mir-7-2 Urinary Bladder Cancer 22768238 A microRNA-7 binding site polymorphism (1010A/G) in HOXB5 leads to differential gene expression in bladder cancer. genetics_GWAS hsa-mir-7-3 Urinary Bladder Cancer 22768238 A microRNA-7 binding site polymorphism (1010A/G) in HOXB5 leads to differential gene expression in bladder cancer. genetics_GWAS hsa-mir-146a Lung Neoplasms 22818121 Our findings suggest that polymorphisms in the rs2910164 of miR-146a and the rs11614913 of miR-196a2 are associated with prognosis in patients with completely resected NSCLC. genetics_GWAS hsa-mir-196a Lung Neoplasms 22818121 Our findings suggest that polymorphisms in the rs2910164 of miR-146a and the rs11614913 of miR-196a2 are associated with prognosis in patients with completely resected NSCLC. genetics_GWAS hsa-mir-146a Asthma 22823586 MiR-146a polymorphism is associated with asthma but not with systemic lupus erythematosus and juvenile rheumatoid arthritis in Mexican patients. genetics_GWAS hsa-mir-1231 "Carcinoma, Hepatocellular" 22824466 A miR-1231 binding site polymorphism (rs17875871) in the 3'UTR of IFNAR1 is associated with hepatocellular carcinoma susceptibility. genetics_GWAS hsa-mir-125b-1 "Leukemia, Myeloid, Acute" 22843432 MicroRNA-125b-1 accelerates a C-terminal mutant of C/EBP¦Á (C/EBP¦Á-C(m))-induced myeloid leukemia. genetics_GWAS hsa-mir-34b Intracranial Aneurysm 22844323 "The CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA compared with the TT genotype. Moreover, a significant gene interaction of the carriers with the combined genotypes of miR-34b/c rs4938723CC and TP53 Arg72Pro CG/CC/GG had a decreased risk of IA, compared with those carrying miR-34b/c rs4938723CT/TT+TP53 Arg72Pro GG/CG/CC combined genotypes." genetics_GWAS hsa-mir-34c Intracranial Aneurysm 22844323 "The CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA compared with the TT genotype. Moreover, a significant gene interaction of the carriers with the combined genotypes of miR-34b/c rs4938723CC and TP53 Arg72Pro CG/CC/GG had a decreased risk of IA, compared with those carrying miR-34b/c rs4938723CT/TT+TP53 Arg72Pro GG/CG/CC combined genotypes." genetics_GWAS hsa-mir-146a Urinary Bladder Cancer 22846912 miR-146a rs2910164 C allele inhibited cell proliferation and significantly downregulates expression of IRAK1 and TRAF6 in bladder cancer cells. genetics_GWAS hsa-mir-196a-1 Esophageal Neoplasms 22859270 MiR-196a binding-site SNP (rs6573) regulates RAP1A expression contributing to esophageal squamous cell carcinoma risk and metastasis. genetics_GWAS hsa-mir-196a-2 Esophageal Neoplasms 22859270 MiR-196a binding-site SNP (rs6573) regulates RAP1A expression contributing to esophageal squamous cell carcinoma risk and metastasis. genetics_GWAS hsa-mir-502 Ovarian Neoplasms 22867998 A polymorphism (rs16917496) at the miR-502 binding site in the 3' untranslated region of the SET8 gene is associated with the risk of epithelial ovarian cancer. genetics_GWAS hsa-let-7a-2 Ovarian Neoplasms 22970210 "We found that there was a reduction in the copy number of let-7 genes in a cancer-type specific manner. Importantly, focal deletion of four let-7 family members was found in three cancer types: medulloblastoma (let-7a-2 and let-7e), breast cancer (let-7a-2), and ovarian cancer (let-7a-3/let-7b)." genetics_GWAS hsa-let-7e Ovarian Neoplasms 22970210 "We found that there was a reduction in the copy number of let-7 genes in a cancer-type specific manner. Importantly, focal deletion of four let-7 family members was found in three cancer types: medulloblastoma (let-7a-2 and let-7e), breast cancer (let-7a-2), and ovarian cancer (let-7a-3/let-7b)." genetics_GWAS hsa-mir-499 Breast Neoplasms 23053947 "In conclusion, this meta-analysis suggests that the miR-499 rs3746444 polymorphism (A>G) is a low-penetrant risk factor for cancer development among Asians and may contribute to breast cancer susceptibility." genetics_GWAS hsa-mir-337 "Leukemia, Myeloid, Acute" 23065518 A polymorphism in the 3'-untranslated region of the NPM1 gene causes illegitimate regulation by microRNA-337-5p and correlates with adverse outcome in acute myeloid leukemia genetics_GWAS hsa-mir-200c Gastric Neoplasms 23065816 G-A variant in miR-200c binding site of EFNA1 alters susceptibility to gastric cancer genetics_GWAS hsa-mir-370 "Leukemia, Myeloid, Acute" 23077663 Integration of SNP and mRNA arrays with microRNA profiling reveals that MiR-370 is upregulated and targets NF1 in acute myeloid leukemia genetics_GWAS hsa-mir-27a "Carcinoma, Renal Cell" 23118855 A genetic variant in pre-miR-27a is associated with a reduced renal cell cancer risk in a Chinese population genetics_GWAS hsa-mir-196a-1 Lung Neoplasms 23143626 Hsa-miR-196a2 functional SNP is associated with severe toxicity after platinum-based chemotherapy of advanced nonsmall cell lung cancer patients in a Chinese population genetics_GWAS hsa-mir-196a-2 Lung Neoplasms 23143626 Hsa-miR-196a2 functional SNP is associated with severe toxicity after platinum-based chemotherapy of advanced nonsmall cell lung cancer patients in a Chinese population genetics_GWAS hsa-mir-30c-1 Lung Neoplasms 23159078 Single nucleotide polymorphism in flanking region of miR-30c influences the maturing process of miR-30c in lung carcinoma genetics_GWAS hsa-mir-30c-2 Lung Neoplasms 23159078 Single nucleotide polymorphism in flanking region of miR-30c influences the maturing process of miR-30c in lung carcinoma genetics_GWAS hsa-mir-146a Acute Cerebral Infarction 23202363 "Association of the miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms With Ischemic Stroke and Silent Brain Infarction Risk" genetics_GWAS hsa-mir-149 Acute Cerebral Infarction 23202363 "Association of the miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms With Ischemic Stroke and Silent Brain Infarction Risk" genetics_GWAS hsa-mir-196a-1 Acute Cerebral Infarction 23202363 "Association of the miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms With Ischemic Stroke and Silent Brain Infarction Risk" genetics_GWAS hsa-mir-196a-2 Acute Cerebral Infarction 23202363 "Association of the miR-146a, miR-149, miR-196a2, and miR-499 Polymorphisms With Ischemic Stroke and Silent Brain Infarction Risk" genetics_GWAS hsa-mir-146a Melanoma 23222547 The rs2910164 G>C polymorphism in microRNA-146a is associated with the incidence of malignant melanoma genetics_GWAS hsa-mir-196a-1 Breast Neoplasms 23228090 Evaluation of single nucleotide polymorphisms in microRNAs (hsa-miR-196a2 rs11614913 C/T) from Brazilian women with breast cancer genetics_GWAS hsa-mir-196a-2 Breast Neoplasms 23228090 Evaluation of single nucleotide polymorphisms in microRNAs (hsa-miR-196a2 rs11614913 C/T) from Brazilian women with breast cancer genetics_GWAS hsa-mir-27a Gastric Neoplasms 23246964 Genetic variations in miR-27a gene decrease mature miR-27a level and reduce gastric cancer susceptibility genetics_GWAS hsa-mir-146a Behcet Disease 23268366 MicroRNA-146a and Ets-1 gene polymorphisms in ocular Behcet's disease and Vogt-Koyanagi-Harada syndrome genetics_GWAS hsa-mir-885 Head And Neck Neoplasms 23271051 A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer genetics_GWAS hsa-mir-149 "Squamous Cell Carcinoma, Head and Neck" 23272122 The Association between Genetic Polymorphism and the Processing Efficiency of miR-149 Affects the Prognosis of Patients with Head and Neck Squamous Cell Carcinoma genetics_GWAS hsa-mir-146a Hepatitis B Virus Infection 23292505 Association of a single-nucleotide polymorphism within the miR-146a gene with susceptibility for acute-on-chronic hepatitis B liver failure genetics_GWAS hsa-mir-146a Colorectal Carcinoma 23306950 A genetic variant in miR-146a modifies colorectal cancer susceptibility in a chinese population genetics_GWAS hsa-mir-218-1 Urinary Bladder Cancer 23320911 The pri-miR-218 rs11134527 SNP was significantly associated with the risk of cervical carcinoma in Eastern Chinese women genetics_GWAS hsa-mir-218-2 Urinary Bladder Cancer 23320911 The pri-miR-218 rs11134527 SNP was significantly associated with the risk of cervical carcinoma in Eastern Chinese women genetics_GWAS hsa-mir-520a Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women genetics_GWAS hsa-mir-520b Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women genetics_GWAS hsa-mir-520c Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women genetics_GWAS hsa-mir-520d Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women genetics_GWAS hsa-mir-520e Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women genetics_GWAS hsa-mir-520f Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women genetics_GWAS hsa-mir-520g Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women genetics_GWAS hsa-mir-520h Endometriosis 23364396 A microRNA-520 mirSNP at the MMP2 gene influences susceptibility to endometriosis in Chinese women genetics_GWAS hsa-mir-22 Heart Failure 23372812 Common variation neighbouring micro-RNA 22 is associated with increased left ventricular mass. genetics_GWAS hsa-mir-367 Colorectal Carcinoma 23393343 the functional variant (rs1044129) in the miR-367 binding site of RYR3 may be a potential marker for prognosis in patients following curative surgery for CRC genetics_GWAS hsa-mir-151a Nasopharyngeal Neoplasms 23416081 A miR-151 binding site polymorphism in the 3'-untranslated region of the cyclin E1 gene associated with nasopharyngeal carcinoma genetics_GWAS hsa-mir-151b Nasopharyngeal Neoplasms 23416081 A miR-151 binding site polymorphism in the 3'-untranslated region of the cyclin E1 gene associated with nasopharyngeal carcinoma genetics_GWAS hsa-mir-125a Breast Neoplasms 23420759 rs12976445 variant in the pri-miR-125a correlates with a lower level of hsa-miR-125a and ERBB2 overexpression in breast cancer patients genetics_GWAS hsa-mir-196a-2 Vitiligo 23433405 A Single Nucleotide Polymorphism of miR-196a-2 and Vitiligo: An Association Study and Functional Analysis in a Han Chinese Population genetics_GWAS hsa-mir-146a Thyroid Neoplasms 23451063 Association between the rs2910164 Polymorphism in Pre-Mir-146a Sequence and Thyroid Carcinogenesis genetics_GWAS hsa-mir-34b Nasopharyngeal Neoplasms 23504554 Interactions of miR-34b/c and TP-53 polymorphisms on the risk of nasopharyngeal carcinoma genetics_GWAS hsa-mir-34c Nasopharyngeal Neoplasms 23504554 Interactions of miR-34b/c and TP-53 polymorphisms on the risk of nasopharyngeal carcinoma genetics_GWAS hsa-mir-196a-1 Hepatitis B Virus Infection 23516510 Associations of pri-miR-34b/c and pre-miR-196a2 Polymorphisms and Their Multiplicative Interactions with Hepatitis B Virus Mutations with Hepatocellular Carcinoma Risk genetics_GWAS hsa-mir-196a-2 Hepatitis B Virus Infection 23516510 Associations of pri-miR-34b/c and pre-miR-196a2 Polymorphisms and Their Multiplicative Interactions with Hepatitis B Virus Mutations with Hepatocellular Carcinoma Risk genetics_GWAS hsa-mir-34b Hepatitis B Virus Infection 23516510 Associations of pri-miR-34b/c and pre-miR-196a2 Polymorphisms and Their Multiplicative Interactions with Hepatitis B Virus Mutations with Hepatocellular Carcinoma Risk genetics_GWAS hsa-mir-34c Hepatitis B Virus Infection 23516510 Associations of pri-miR-34b/c and pre-miR-196a2 Polymorphisms and Their Multiplicative Interactions with Hepatitis B Virus Mutations with Hepatocellular Carcinoma Risk genetics_GWAS hsa-mir-196a Neoplasms [unspecific] 23691458 "The meta-analysis demonstrated that the miR-196a-2 polymorphism is associated with cancer susceptibility, especially lung cancer, colorectal cancer, and breast cancer among Asian populations." genetics_GWAS hsa-mir-184 Gastric Neoplasms 23724109 The miR-184 Binding-Site rs8126 T>C Polymorphism in TNFAIP2 Is Associated with Risk of Gastric Cancer. genetics_GWAS hsa-mir-137 Psychiatric Disorders 23786914 Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex. genetics_GWAS hsa-mir-196a-2 "Carcinoma, Hepatocellular" 23791656 Three common functional polymorphisms in microRNA encoding genes in the susceptibility to hepatocellular carcinoma: a systematic review and meta-analysis. genetics_GWAS hsa-mir-499 "Carcinoma, Hepatocellular" 23791656 Three common functional polymorphisms in microRNA encoding genes in the susceptibility to hepatocellular carcinoma: a systematic review and meta-analysis. genetics_GWAS hsa-mir-146a "Squamous Cell Carcinoma, Esophageal" 23792053 "These findings indicated that functional polymorphism miR-196a2 rs11614913 T > C might contribute to decreased ESCC risk among women patients and patients who never smoking or drinking. However, our results were obtained with a limited sample size. Future larger studies with other ethnic populations and tissue-specific biological characterization are required to confirm current findings." genetics_GWAS hsa-mir-196a-2 "Squamous Cell Carcinoma, Esophageal" 23792053 "These findings indicated that functional polymorphism miR-196a2 rs11614913 T > C might contribute to decreased ESCC risk among women patients and patients who never smoking or drinking. However, our results were obtained with a limited sample size. Future larger studies with other ethnic populations and tissue-specific biological characterization are required to confirm current findings." genetics_GWAS hsa-mir-26a-1 "Squamous Cell Carcinoma, Esophageal" 23792053 "These findings indicated that functional polymorphism miR-196a2 rs11614913 T > C might contribute to decreased ESCC risk among women patients and patients who never smoking or drinking. However, our results were obtained with a limited sample size. Future larger studies with other ethnic populations and tissue-specific biological characterization are required to confirm current findings." genetics_GWAS hsa-mir-27a "Squamous Cell Carcinoma, Esophageal" 23792053 "These findings indicated that functional polymorphism miR-196a2 rs11614913 T > C might contribute to decreased ESCC risk among women patients and patients who never smoking or drinking. However, our results were obtained with a limited sample size. Future larger studies with other ethnic populations and tissue-specific biological characterization are required to confirm current findings." genetics_GWAS hsa-mir-499 "Squamous Cell Carcinoma, Esophageal" 23792053 "These findings indicated that functional polymorphism miR-196a2 rs11614913 T > C might contribute to decreased ESCC risk among women patients and patients who never smoking or drinking. However, our results were obtained with a limited sample size. Future larger studies with other ethnic populations and tissue-specific biological characterization are required to confirm current findings." genetics_GWAS hsa-mir-146a Coronary Artery Disease 23794009 "miR-146a polymorphism influences levels of miR-146a, IRAK-1, and TRAF-6 in young patients with coronary artery disease." genetics_GWAS hsa-mir-608 "Carcinoma, Nasopharyngeal" 23796562 A sequence polymorphism in miR-608 predicts recurrence after radiotherapy for nasopharyngeal carcinoma. genetics_GWAS hsa-mir-124 Hepatitis B Virus Infection 23807362 Association between microRNA polymorphisms and humoral immunity to hepatitis B vaccine. genetics_GWAS hsa-mir-146a Hepatitis B Virus Infection 23807362 Association between microRNA polymorphisms and humoral immunity to hepatitis B vaccine. genetics_GWAS hsa-mir-149 Hepatitis B Virus Infection 23807362 Association between microRNA polymorphisms and humoral immunity to hepatitis B vaccine. genetics_GWAS hsa-mir-196a-2 Hepatitis B Virus Infection 23807362 Association between microRNA polymorphisms and humoral immunity to hepatitis B vaccine. genetics_GWAS hsa-mir-26a-1 Hepatitis B Virus Infection 23807362 Association between microRNA polymorphisms and humoral immunity to hepatitis B vaccine. genetics_GWAS hsa-mir-27a Hepatitis B Virus Infection 23807362 Association between microRNA polymorphisms and humoral immunity to hepatitis B vaccine. genetics_GWAS hsa-mir-146 Colorectal Carcinoma 23898084 "The current study provides evidence that the miR-146a rs2690164 polymorphism, as the dominant model of the G allele, is associated with the susceptibility and prognosis of CRC." genetics_GWAS hsa-mir-182 Hyperactivity Disorder 23906647 Evaluation of single nucleotide polymorphisms in the miR-183-96-182 cluster in adulthood attention-deficit and hyperactivity disorder (ADHD) and substance use disorders (SUDs). genetics_GWAS hsa-mir-183 Hyperactivity Disorder 23906647 Evaluation of single nucleotide polymorphisms in the miR-183-96-182 cluster in adulthood attention-deficit and hyperactivity disorder (ADHD) and substance use disorders (SUDs). genetics_GWAS hsa-mir-96 Hyperactivity Disorder 23906647 Evaluation of single nucleotide polymorphisms in the miR-183-96-182 cluster in adulthood attention-deficit and hyperactivity disorder (ADHD) and substance use disorders (SUDs). genetics_GWAS hsa-mir-34b "Carcinoma, Hepatocellular" 23935875 Lack of association of MiR-34b/c polymorphism (rs4938723) with hepatocellular carcinoma: a meta-analysis. genetics_GWAS hsa-mir-31 Hypertension 23943853 Human angiotensinogen +11525 C/A polymorphism modulates its gene expression through microRNA binding. genetics_GWAS hsa-mir-584 Hypertension 23943853 Human angiotensinogen +11525 C/A polymorphism modulates its gene expression through microRNA binding. genetics_GWAS hsa-mir-27a Breast Neoplasms 23954879 A genetic variant in pre-miR-27a is associated with a reduced breast cancer risk in younger Chinese population. genetics_GWAS hsa-mir-146a Gastric Neoplasms 23975664 Prognostic role of microRNA polymorphisms in advanced gastric cancer: a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). genetics_GWAS hsa-mir-196a-2 Gastric Neoplasms 23975664 Prognostic role of microRNA polymorphisms in advanced gastric cancer: a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). genetics_GWAS hsa-mir-219-1 Gastric Neoplasms 23975664 Prognostic role of microRNA polymorphisms in advanced gastric cancer: a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). genetics_GWAS hsa-mir-26a-1 Gastric Neoplasms 23975664 Prognostic role of microRNA polymorphisms in advanced gastric cancer: a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). genetics_GWAS hsa-mir-27a Gastric Neoplasms 23975664 Prognostic role of microRNA polymorphisms in advanced gastric cancer: a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). genetics_GWAS hsa-mir-423 Gastric Neoplasms 23975664 Prognostic role of microRNA polymorphisms in advanced gastric cancer: a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO). genetics_GWAS hsa-mir-196a-2 Breast Neoplasms 23982873 "the current meta-analysis supports that the miR-196a-2 rs11614913*T, miR-499 rs3746444*T, miR-605 rs2043556*A, and miR-27a rs895919*C alleles might be protective factors for breast cancer" genetics_GWAS hsa-mir-27a Breast Neoplasms 23982873 "the current meta-analysis supports that the miR-196a-2 rs11614913*T, miR-499 rs3746444*T, miR-605 rs2043556*A, and miR-27a rs895919*C alleles might be protective factors for breast cancer" genetics_GWAS hsa-mir-499 Breast Neoplasms 23982873 "the current meta-analysis supports that the miR-196a-2 rs11614913*T, miR-499 rs3746444*T, miR-605 rs2043556*A, and miR-27a rs895919*C alleles might be protective factors for breast cancer" genetics_GWAS hsa-mir-605 Breast Neoplasms 23982873 "the current meta-analysis supports that the miR-196a-2 rs11614913*T, miR-499 rs3746444*T, miR-605 rs2043556*A, and miR-27a rs895919*C alleles might be protective factors for breast cancer" genetics_GWAS hsa-mir-146a Breast Neoplasms 24039706 "This meta-analysis demonstrates the compelling evidence that the rs11614913 CC genotype in miR-196a2 increases breast cancer risk, which provides useful information for the early diagnosis and prevention of breast cancer." genetics_GWAS hsa-mir-196a Breast Neoplasms 24039706 "This meta-analysis demonstrates the compelling evidence that the rs11614913 CC genotype in miR-196a2 increases breast cancer risk, which provides useful information for the early diagnosis and prevention of breast cancer." genetics_GWAS hsa-mir-499 Breast Neoplasms 24039706 "This meta-analysis demonstrates the compelling evidence that the rs11614913 CC genotype in miR-196a2 increases breast cancer risk, which provides useful information for the early diagnosis and prevention of breast cancer." genetics_GWAS hsa-mir-149 "Carcinoma, Hepatocellular" 24040059 Results of this meta-analysis suggest that the hsa-miR-149 rs2292832 polymorphism is not associated with cancer risk in spite of the potentially protective role of C allele in hepatocellular carcinoma and male gastric cancer. genetics_GWAS hsa-mir-21 Bladder Neoplasms 24078506 "In accordance to the observed similarity between TGF-¦Â variants and miR-21 gene expression alterations in bladder tumors, treating 5637 bladder cancer cell line with TGF-¦Â recombinant protein caused a significant upregulation of miR-21. The later finding further confirmed a correlated expression of TGF-¦Âand miR-21 in bladder tumors." genetics_GWAS hsa-mir-499 Neoplasms [unspecific] 24085457 The miR-499 rs3746444 polymorphism is associated with an increased cancer risk. genetics_GWAS hsa-mir-499 Gastric Neoplasms 24107911 The rs3746444 (A>G) SNP is not associated with susceptibility to GC in the Chinese population. genetics_GWAS hsa-mir-218 "Carcinoma, Hepatocellular" 24118778 "rs11134527 may be a novel genetic risk factor of HCC in HBV-exposed subjects, can facilitate HBV preS deletion generation and predispose the host to the effect of T1674C/G and preS1 start codon mutation in hepatocarcinogenesis." genetics_GWAS hsa-mir-137 Schizophrenia 24132022 Impact of the genome-wide schizophrenia risk single nucleotide polymorphism (rs1625579) in miR-137 on brain structures in healthy individuals. genetics_GWAS hsa-mir-146a Colorectal Carcinoma 24136745 Association between microRNA genetic variants and susceptibility to colorectal cancer in Chinese population. genetics_GWAS hsa-mir-184 Cataract 24138095 "C.57 C > T Mutation in MIR 184 is Responsible for Congenital Cataracts and Corneal Abnormalities in a Five-generation Family from Galicia, Spain." genetics_GWAS hsa-mir-146a Lung Neoplasms 24144839 "These findings suggest that the rs2910164C>G in pre-miR-146a may contribute to genetic susceptibility to lung cancer, and that miR-146a might be involved in lung cancer development." genetics_GWAS hsa-mir-502 "Carcinoma, Lung, Non-Small-Cell" 24146953 Our data suggested that the rs16917496 T>C located at miR-502 binding site contributes to NSCLC survival by altering SET8 expression through modulating miRNA-target interaction. genetics_GWAS hsa-mir-561 "Carcinoma, Breast" 24166930 Genetic variant rs16430 6bp > 0bp at the microRNA-binding site in TYMS and risk of sporadic breast cancer risk in non-Hispanic white women aged ¡Ü 55 years. genetics_GWAS hsa-mir-423 "Squamous Cell Carcinoma, Esophageal" 24205249 MicroRNA polymorphisms and environmental smoke exposure as risk factors for oesophageal squamous cell carcinoma. genetics_GWAS hsa-mir-27a "Carcinoma, Lung, Non-Small-Cell" 24223174 Our results suggest that the pre-miR-27a rs895819 polymorphism may influence NSCLC patients' clinical outcome. Further large sample studies should be used to validate our findings. genetics_GWAS hsa-mir-146a "Carcinoma, Lung" 24246082 The rs2910164 C allele in pre-miR-146a and rs11614913 C allele in pre-miR-196a2 were associated with increased genetic damage levels in coke oven workers genetics_GWAS hsa-mir-196a-2 "Carcinoma, Lung" 24246082 The rs2910164 C allele in pre-miR-146a and rs11614913 C allele in pre-miR-196a2 were associated with increased genetic damage levels in coke oven workers genetics_GWAS hsa-mir-146a Digestive System Neoplasms 24247819 miR-146a gene polymorphism rs2910164 and the risk of digestive tumors: A meta-analysis of 21 case-control studies. genetics_GWAS hsa-mir-196a-2 Chronic Hepatitis B 24248733 MicroRNA-196A-2 polymorphisms and hepatocellular carcinoma in patients with chronic hepatitis B. genetics_GWAS hsa-mir-499 Neoplasms [unspecific] 24258110 Quantitative assessment of the association between microRNA-499 rs3746444 A/G polymorphism and cancer risk. genetics_GWAS hsa-mir-34b "Carcinoma, Esophageal" 24260422 Hsa-miR-34b/c rs4938723 T>C and hsa-miR-423 rs6505162 C>A polymorphisms are associated with the risk of esophageal cancer in a Chinese population. genetics_GWAS hsa-mir-34c "Carcinoma, Esophageal" 24260422 Hsa-miR-34b/c rs4938723 T>C and hsa-miR-423 rs6505162 C>A polymorphisms are associated with the risk of esophageal cancer in a Chinese population. genetics_GWAS hsa-mir-423 "Carcinoma, Esophageal" 24260422 Hsa-miR-34b/c rs4938723 T>C and hsa-miR-423 rs6505162 C>A polymorphisms are associated with the risk of esophageal cancer in a Chinese population. genetics_GWAS hsa-mir-146a Neoplasms [unspecific] 24278149 Association between microRNA polymorphisms and cancer risk based on the findings of 66 case-control studies. genetics_GWAS hsa-mir-149 Neoplasms [unspecific] 24278149 Association between microRNA polymorphisms and cancer risk based on the findings of 66 case-control studies. genetics_GWAS hsa-mir-196a-2 Neoplasms [unspecific] 24278149 Association between microRNA polymorphisms and cancer risk based on the findings of 66 case-control studies. genetics_GWAS hsa-mir-499 Neoplasms [unspecific] 24278149 Association between microRNA polymorphisms and cancer risk based on the findings of 66 case-control studies. genetics_GWAS hsa-mir-100 "Squamous Cell Carcinoma, Esophageal" 24288122 "Taken together, these findings indicate that miRNA polymorphisms may predict prognosis in advanced ESCC patients receiving platinum-based chemotherapy." genetics_GWAS hsa-mir-125a "Squamous Cell Carcinoma, Esophageal" 24288122 "Taken together, these findings indicate that miRNA polymorphisms may predict prognosis in advanced ESCC patients receiving platinum-based chemotherapy." genetics_GWAS hsa-mir-146a "Squamous Cell Carcinoma, Esophageal" 24288122 "Taken together, these findings indicate that miRNA polymorphisms may predict prognosis in advanced ESCC patients receiving platinum-based chemotherapy." genetics_GWAS hsa-mir-196a-2 "Squamous Cell Carcinoma, Esophageal" 24288122 "Taken together, these findings indicate that miRNA polymorphisms may predict prognosis in advanced ESCC patients receiving platinum-based chemotherapy." genetics_GWAS hsa-mir-26a-1 "Squamous Cell Carcinoma, Esophageal" 24288122 "Taken together, these findings indicate that miRNA polymorphisms may predict prognosis in advanced ESCC patients receiving platinum-based chemotherapy." genetics_GWAS hsa-mir-34b Oral Neoplasms 24297336 Genetic variations at microRNA and processing genes and risk of oral cancer. genetics_GWAS hsa-mir-499 "Carcinoma, Hepatocellular" 24301908 miR-499A>G rs3746444 and miR-146aG>C expression and hepatocellular carcinoma risk in the Chinese population. genetics_GWAS hsa-mir-27b Bladder Neoplasms 24312312 "Taken together, these findings suggested that DROSHA rs10719T>C polymorphism may be associated with bladder cancer risk in a Chinese population, and hsa-miR-27b can influence the expression of DROSHA protein by binding with 3'UTR." genetics_GWAS hsa-mir-196a-2 "Squamous Cell Carcinoma, Esophageal" 24320161 These results suggest that the miRNA-196a2 functional polymorphism rs11614913 might be an effective genetic marker for ESCC risk assessment in individuals younger than 60 years of age from a region of high ESCC incidence in northern China. genetics_GWAS hsa-mir-499 Rheumatoid Arthritis 24327058 This study suggested that miR-499 polymorphisms were associated with a significantly increased risk of RA in Mediterranean populations. genetics_GWAS hsa-mir-21 "Squamous Cell Carcinoma, Head and Neck" 24327270 "CLU is a specific, functional target of oncogenic miRNA-21 in HNSCCs. CLU-1 isoform is the predominant growth-suppressive variant targeted by miRNA-21." genetics_GWAS hsa-mir-34b Colorectal Carcinoma 24337371 Polymorphisms of the pri-miR-34b/c promoter and TP53 codon 72 are associated with risk of colorectal cancer. genetics_GWAS hsa-mir-34c Colorectal Carcinoma 24337371 Polymorphisms of the pri-miR-34b/c promoter and TP53 codon 72 are associated with risk of colorectal cancer. genetics_GWAS hsa-mir-125b Endometriosis 24339876 Genetic variation at the miR-125b binding site may play functional roles to protect against endometriosis progression. genetics_GWAS hsa-mir-502 "Carcinoma, Lung, Non-Small-Cell" 24374662 Association of miR-502-binding site single nucleotide polymorphism in the 3'-untranslated region of SET8 and TP53 codon 72 polymorphism with non-small cell lung cancer in Chinese population. genetics_GWAS hsa-mir-146a "Carcinoma, Hepatocellular" 24377574 "Our results demonstrate that miR-196a4 CC genotype and C allele have an important role in HCC risk in Chinese, especially in patients with HBV infection." genetics_GWAS hsa-mir-196a "Carcinoma, Hepatocellular" 24377574 "Our results demonstrate that miR-196a2 CC genotype and C allele have an important role in HCC risk in Chinese, especially in patients with HBV infection." genetics_GWAS hsa-mir-499 "Carcinoma, Hepatocellular" 24377574 "Our results demonstrate that miR-196a3 CC genotype and C allele have an important role in HCC risk in Chinese, especially in patients with HBV infection." genetics_GWAS hsa-mir-146a Gastric Neoplasms 24379078 "Association of the miR-146aC>G, miR-149T>C, and miR-196a2T>C polymorphisms with gastric cancer risk and survival in the Greek population." genetics_GWAS hsa-mir-149 Gastric Neoplasms 24379078 "Association of the miR-146aC>G, miR-149T>C, and miR-196a2T>C polymorphisms with gastric cancer risk and survival in the Greek population." genetics_GWAS hsa-mir-196a-2 Gastric Neoplasms 24379078 "Association of the miR-146aC>G, miR-149T>C, and miR-196a2T>C polymorphisms with gastric cancer risk and survival in the Greek population." genetics_GWAS hsa-mir-27a "Carcinoma, Cervical" 24380734 A genetic variant in pre-miR-27a is associated with a reduced cervical cancer risk in southern Chinese women. genetics_GWAS hsa-mir-485 Hyperglycemia 24387992 An APOA5 3' UTR variant associated with plasma triglycerides triggers APOA5 downregulation by creating a functional miR-485-5p binding site. genetics_GWAS hsa-mir-146a Colorectal Carcinoma 24399071 Effects of common polymorphisms rs2910164 in miR-146a and rs11614913 in miR-196a2 on susceptibility to colorectal cancer: a systematic review meta-analysis. genetics_GWAS hsa-mir-196a-2 Colorectal Carcinoma 24399071 Effects of common polymorphisms rs2910164 in miR-146a and rs11614913 in miR-196a2 on susceptibility to colorectal cancer: a systematic review meta-analysis. genetics_GWAS hsa-mir-106b "Carcinoma, Hepatocellular" 24416400 A genetic variant in the promoter region of miR-106b-25 cluster predict clinical outcome of HBV-related hepatocellular carcinoma in Chinese. genetics_GWAS hsa-mir-330 Psychiatric Disorders 24436253 The effects of a MAP2K5 microRNA target site SNP on risk for anxiety and depressive disorders. genetics_GWAS hsa-mir-146 Coronary Artery Disease 24447667 A common variant in pre-miR-146 is associated with coronary artery disease risk and its mature miRNA expression. genetics_GWAS hsa-mir-135b "Carcinoma, Cervical" 24465869 Genetic variants in microRNA target sites of 37 selected cancer-related genes and the risk of cervical cancer. genetics_GWAS hsa-mir-101-1 Breast Neoplasms 24475105 Genetic variations in the flanking regions of miR-101-2 are associated with increased risk of breast cancer. genetics_GWAS hsa-mir-101-2 Breast Neoplasms 24475105 Genetic variations in the flanking regions of miR-101-2 are associated with increased risk of breast cancer. genetics_GWAS hsa-mir-146a Immune Thrombocytopenic Purpura 24502829 hsa-mir-146a rs2910164 polymorphism and risk of immune thrombocytopenia. genetics_GWAS hsa-mir-34b "Carcinoma, Renal Cell" 24503183 A potentially functional polymorphism in the promoter region of miR-34b/c is associated with renal cell cancer risk in a Chinese population. genetics_GWAS hsa-mir-34c "Carcinoma, Renal Cell" 24503183 A potentially functional polymorphism in the promoter region of miR-34b/c is associated with renal cell cancer risk in a Chinese population. genetics_GWAS hsa-mir-499 Breast Neoplasms 24521023 Our findings demonstrated that the hsa-mir-499 rs3746444 polymorphism is associated with higher risk of developing breast cancer in our population. genetics_GWAS hsa-mir-146a Gastric Neoplasms 24528016 A genetic variant in MiR-146a modifies digestive system cancer risk: a meta-analysis. genetics_GWAS hsa-mir-146a Colorectal Carcinoma 24568449 These findings supported that the miR-196a2 rs11614913 and miR-149 rs2292832 polymorphisms may contribute to susceptibility to CRC. genetics_GWAS hsa-mir-149 Colorectal Carcinoma 24568449 These findings supported that the miR-196a2 rs11614913 and miR-149 rs2292832 polymorphisms may contribute to susceptibility to CRC. genetics_GWAS hsa-mir-196a Colorectal Carcinoma 24568449 These findings supported that the miR-196a2 rs11614913 and miR-149 rs2292832 polymorphisms may contribute to susceptibility to CRC. genetics_GWAS hsa-mir-499 Colorectal Carcinoma 24568449 These findings supported that the miR-196a2 rs11614913 and miR-149 rs2292832 polymorphisms may contribute to susceptibility to CRC. genetics_GWAS hsa-mir-624 Gastric Neoplasms 24568522 Bioinformatic prediction of SNPs within miRNA binding sites of inflammatory genes associated with gastric cancer. genetics_GWAS hsa-mir-146a Alzheimer Disease 24586483 A functional polymorphism in the promoter region of microRNA-146a is associated with the risk of Alzheimer disease and the rate of cognitive decline in patients. genetics_GWAS hsa-mir-146a "Carcinoma, Hepatocellular" 24587132 "These results suggest that a significant association exists between miRNA499 SNPs and hepatocellular carcinoma. Gene-environment interactions of miRNA499 polymorphisms, smoking, and alcohol consumption might alter hepatocellular carcinoma susceptibility." genetics_GWAS hsa-mir-149 "Carcinoma, Hepatocellular" 24587132 "These results suggest that a significant association exists between miRNA499 SNPs and hepatocellular carcinoma. Gene-environment interactions of miRNA499 polymorphisms, smoking, and alcohol consumption might alter hepatocellular carcinoma susceptibility." genetics_GWAS hsa-mir-196 "Carcinoma, Hepatocellular" 24587132 "These results suggest that a significant association exists between miRNA499 SNPs and hepatocellular carcinoma. Gene-environment interactions of miRNA499 polymorphisms, smoking, and alcohol consumption might alter hepatocellular carcinoma susceptibility." genetics_GWAS hsa-mir-499 "Carcinoma, Hepatocellular" 24587132 "These results suggest that a significant association exists between miRNA499 SNPs and hepatocellular carcinoma. Gene-environment interactions of miRNA499 polymorphisms, smoking, and alcohol consumption might alter hepatocellular carcinoma susceptibility." genetics_GWAS hsa-mir-124 "Carcinoma, Cervical" 24589598 "miR-124 rs531564 polymorphism may play a role in cervical cancer susceptibility in Chinese Han women, and G allele is associated with a reduced risk of cervical cancer." genetics_GWAS hsa-mir-526b "Carcinoma, Gastric" 24595048 The has-miR-526b binding-site rs8506G>a polymorphism in the lincRNA-NR_024015 exon identified by GWASs predispose to non-cardia gastric cancer risk. genetics_GWAS hsa-mir-3649 Non-Syndromic Orofacial Clefts 24603642 "Taken together, these findings indicate that SNPs in the miRNA-binding sites might play an important role in the development of NSOCs. Furthermore, if confirmed in subsequent studies, the polymorphisms may be considered as additional markers for the evaluation of infants' risk of NSOCs." genetics_GWAS hsa-mir-146a "Carcinoma, Hepatocellular" 24615520 miR-146a G>C polymorphisms and risk of hepatocellular carcinoma in a Chinese population. genetics_GWAS hsa-mir-499 "Leukemia, Lymphoblastic, Acute" 24618566 "We found 11 SNPs significantly associated with ALL susceptibility. These included three SNPs present in miRNA genes (miR-612, miR-499, and miR-449b) and eight SNPs present in six miRNA biogenesis pathway genes (TNRC6B, DROSHA, DGCR8, EIF2C1, CNOT1, and CNOT6)." genetics_GWAS hsa-mir-146a Alcohol Use Disorder 24630744 This is the first genetic association study to explore the relationship of miRNA polymorphisms with AUDs and to show an association of the miR-146a C>G rs2910164 allelic variant with this disease. genetics_GWAS hsa-mir-196a-2 Liver Neoplasms 24633889 "Quantitative assessment of the association between miR-196a2 rs11614913 polymorphism and cancer risk: evidence based on 45,816 subjects." genetics_GWAS hsa-mir-2278 Multiple Sclerosis 24638856 Assessment of microRNA-related SNP effects in the 3' untranslated region of the IL22RA2 risk locus in multiple sclerosis. genetics_GWAS hsa-mir-411 Multiple Sclerosis 24638856 Assessment of microRNA-related SNP effects in the 3' untranslated region of the IL22RA2 risk locus in multiple sclerosis. genetics_GWAS hsa-mir-146a Uveitis 24658012 This study shows that miR-146a and Ets-1 are both associated with pediatric uveitis in Han Chinese. SNP rs10893872 may affect the genetic predisposition to pediatric uveitis by modulating expression of Ets-1. genetics_GWAS hsa-mir-4436b-1 Autism Spectrum Disorder 24667286 Assessing the impact of copy number variants on miRNA genes in autism by Monte Carlo simulation. genetics_GWAS hsa-mir-4436b-2 Autism Spectrum Disorder 24667286 Assessing the impact of copy number variants on miRNA genes in autism by Monte Carlo simulation. genetics_GWAS hsa-mir-424 Myelodysplastic Syndromes 24674452 Detection of an activated JAK3 variant and a Xq26.3 microdeletion causing loss of PHF6 and miR-424 expression in myelodysplastic syndromes by combined targeted next generation sequencing and SNP array analysis. genetics_GWAS hsa-mir-224 Coronary Artery Disease 24676100 Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. genetics_GWAS hsa-mir-149 "Carcinoma, Renal Cell" 24681820 "We genotyped four common miRNA SNPs (i.e. miR-146a rs2910164, miR-149 rs2292832, miR-196a2 rs11614913 and miR-499 rs3746444) to assess their associations with RCC risk in a two-stage case-control study (355 cases and 362 controls in discovery set, meanwhile 647 cases and 660 controls in validation set), as well as RCC survival in 311 patients." genetics_GWAS hsa-mir-518 Hypertension 24687999 Our results suggest that TGFBR2 and miR-518 harbor variants that increase the risk of EH and affect blood pressure homeostasis as well as efficacy of antihypertensive agents. genetics_GWAS hsa-mir-146a Skin Neoplasms 24699816 "we investigated the impact of MIR146A SNP rs2910164 on cancer risk, and interaction with a SNP in one of its putative targets (RNASEL, rs486907)." genetics_GWAS hsa-mir-146a Sepsis 24701036 The functional polymorphisms of miR-146a are associated with susceptibility to severe sepsis in the Chinese population. genetics_GWAS hsa-mir-146a Dermatomyositis 24716199 MIRSNP rs2910164 of miR-146a is associated with the muscle involvement in polymyositis/dermatomyositis. genetics_GWAS hsa-mir-146a Neoplasms [unspecific] 24716941 Association analysis of single nucleotide polymorphisms in miR-146a and miR-196a2 on the prevalence of cancer in elderly Japanese: a case-control study. genetics_GWAS hsa-mir-196a-2 Neoplasms [unspecific] 24716941 Association analysis of single nucleotide polymorphisms in miR-146a and miR-196a2 on the prevalence of cancer in elderly Japanese: a case-control study. genetics_GWAS hsa-mir-142 "Leukemia, Myeloid, Acute" 24724784 Absence of miR-142 mutation in Chinese patients with acute myeloid leukemia. genetics_GWAS hsa-let-7 "Carcinoma, Colon" 24727325 "In the largest association study investigating the LCS6 polymorphism in colon cancers, the germline LCS6 genotype was not associated with KRAS mutation status or with clinical outcome in patients with stage III tumors." genetics_GWAS hsa-let-7 Hepatitis B Virus Infection 24729511 Association of a functional RAD52 genetic variant locating in a miRNA binding site with risk of HBV-related hepatocellular carcinoma. genetics_GWAS hsa-mir-146a Colorectal Carcinoma 24740563 Association of a genetic variant in microRNA-146a with risk of colorectal cancer: a population-based case-control study. genetics_GWAS hsa-mir-378 "Carcinoma, Hepatocellular" 24751683 These findings indicate that rs1076064 may be a biomarker for HCC susceptibility and prognosis through altering pri-miR-378 transcription. genetics_GWAS hsa-mir-143 Congenital Heart Diseases 24752771 No association of pri-miR-143 rs41291957 polymorphism with the risk of congenital heart disease in a Chinese population. genetics_GWAS hsa-let-7a Gastric Neoplasms 24760009 "pri-let-7a-2 rs629367 CC genotype could increase the risks of gastric cancer as well as atrophic gastritis and was also associated with poor survival of gastric cancer, which possibly by affecting the mature let-7a expression, and could serve as a predicting biomarker for high-risk and poor prognosis of gastric cancer." genetics_GWAS hsa-mir-218 Neoplasms [unspecific] 24761857 "The findings suggest that pre-miR-218 rs11134527 polymorphism may have some relation to cancer development in Chinese. However, well-designed studies with larger sample size and more detailed data are needed to confirm these conclusions." genetics_GWAS hsa-mir-608 "Squamous Cell Carcinoma, Esophageal" 24770678 "The hereditary genetic polymorphisms of mir-608, RAN, and GEMIN4 can serve as predictors for clinical outcome in ESCC patients treated with concurrent chemoradiotherapy." genetics_GWAS hsa-mir-146a IgA Nephropathy 24781267 These results indicated that rs2910164 may affect the susceptibility and severity of pediatric IgAN. Further studies are needed to validate these findings. genetics_GWAS hsa-mir-182 Behcet Disease 24801147 Predisposition to Behcet's disease and VKH syndrome by genetic variants of miR-182. genetics_GWAS hsa-mir-146a Systemic Lupus Erythematosus 24803388 Association of miR-146a polymorphisms with systemic lupus erythematosus: a meta-analysis. genetics_GWAS hsa-mir-26b Obesity 24807789 "Expression of microRNA-26b, an obesity-related microRNA, is regulated by free fatty acids, glucose, dexamethasone and growth hormone in human adipocytes." genetics_GWAS hsa-mir-146a "Carcinoma, Hepatocellular" 24816919 Association between miR-146aG>C and miR-196a2C>T polymorphisms and the risk of hepatocellular carcinoma in a Chinese population. genetics_GWAS hsa-mir-196a-2 "Carcinoma, Hepatocellular" 24816919 Association between miR-146aG>C and miR-196a2C>T polymorphisms and the risk of hepatocellular carcinoma in a Chinese population. genetics_GWAS hsa-mir-499 "Carcinoma, Hepatocellular" 24816919 Association between miR-146aG>C and miR-196a2C>T polymorphisms and the risk of hepatocellular carcinoma in a Chinese population. genetics_GWAS hsa-mir-146a Rheumatoid Arthritis 24824381 Association of two polymorphisms rs2910164 in miRNA-146a and rs3746444 in miRNA-499 with rheumatoid arthritis: a meta-analysis. genetics_GWAS hsa-mir-499 Rheumatoid Arthritis 24824381 Association of two polymorphisms rs2910164 in miRNA-146a and rs3746444 in miRNA-499 with rheumatoid arthritis: a meta-analysis. genetics_GWAS hsa-mir-33b Hyperglycemia 24825092 Association of rs8066560 variant in the sterol regulatory element-binding protein 1 (SREBP-1) and miR-33b genes with hyperglycemia and insulin resistance. genetics_GWAS hsa-mir-146a Myocardial Infarction 24850191 Association of microRNA polymorphisms with the risk of myocardial infarction in a Chinese population. genetics_GWAS hsa-mir-149 Myocardial Infarction 24850191 Association of microRNA polymorphisms with the risk of myocardial infarction in a Chinese population. genetics_GWAS hsa-mir-196a-2 Myocardial Infarction 24850191 Association of microRNA polymorphisms with the risk of myocardial infarction in a Chinese population. genetics_GWAS hsa-mir-218 Myocardial Infarction 24850191 Association of microRNA polymorphisms with the risk of myocardial infarction in a Chinese population. genetics_GWAS hsa-mir-499 Myocardial Infarction 24850191 Association of microRNA polymorphisms with the risk of myocardial infarction in a Chinese population. genetics_GWAS hsa-mir-196a-2 "Carcinoma, Lung, Non-Small-Cell" 24853117 "Importantly, this method can be further applied to analyze the point mutation of mir-196a2 in the lung tissues of non small-cell lung cancer patients." genetics_GWAS hsa-mir-499 "Carcinoma, Hepatocellular" 24854593 "miR-499 rs3746444 may contribute to the risk and prognosis of HCC, indicating that this SNP could be developed as a biomarker for HCC prediction." genetics_GWAS hsa-mir-29a Oral Neoplasms 24885463 Variations in microRNAs and their processing genes modulated risk of precancer but further in-depth study is needed to understand mechanism of disease process. genetics_GWAS hsa-mir-34b Oral Neoplasms 24885463 Variations in microRNAs and their processing genes modulated risk of precancer but further in-depth study is needed to understand mechanism of disease process. genetics_GWAS hsa-mir-423 Oral Neoplasms 24885463 Variations in microRNAs and their processing genes modulated risk of precancer but further in-depth study is needed to understand mechanism of disease process. genetics_GWAS hsa-mir-34c "Leukemia, Myeloid" 24886876 Our study implicates that microRNA-binding site polymorphisms modulate leukemia risk by interfering with the miRNA-mediated regulation. Our findings underscore the significance of variability in 3' untranslated regions in leukemia. genetics_GWAS hsa-mir-449b "Leukemia, Myeloid" 24886876 Our study implicates that microRNA-binding site polymorphisms modulate leukemia risk by interfering with the miRNA-mediated regulation. Our findings underscore the significance of variability in 3' untranslated regions in leukemia. genetics_GWAS hsa-let-7 Colorectal Carcinoma 24890702 Let-7 microRNA-binding-site polymorphism in the 3'UTR of KRAS and colorectal cancer outcome: a systematic review and meta-analysis. genetics_GWAS hsa-mir-196a Breast Neoplasms 24922658 The current study provides evidence that the miR-196a rs11614913T>C polymorphisms are possible prognostic biomarker for patients with hormone receptor-expressing early breast cancer. genetics_GWAS hsa-mir-603 Colorectal Carcinoma 24934365 "Our data suggest that hsa-miR-603 may be involved in colorectal tumorigenesis, and the genetic polymorphism in hsa-miR-603 is associated with CRC susceptibility." genetics_GWAS hsa-mir-124 "Squamous Cell Carcinoma, Esophageal" 24945256 Pri-miR-124 rs531564 and pri-miR-34b/c rs4938723 polymorphisms are associated with decreased risk of esophageal squamous cell carcinoma in Chinese populations. genetics_GWAS hsa-mir-34b "Squamous Cell Carcinoma, Esophageal" 24945256 Pri-miR-124 rs531564 and pri-miR-34b/c rs4938723 polymorphisms are associated with decreased risk of esophageal squamous cell carcinoma in Chinese populations. genetics_GWAS hsa-mir-34c "Squamous Cell Carcinoma, Esophageal" 24945256 Pri-miR-124 rs531564 and pri-miR-34b/c rs4938723 polymorphisms are associated with decreased risk of esophageal squamous cell carcinoma in Chinese populations. genetics_GWAS hsa-mir-146a "Stroke, Ischemic" 24952884 miR-146a and miR-196a2 polymorphisms in patients with ischemic stroke in the northern Chinese Han population. genetics_GWAS hsa-mir-196a-2 "Stroke, Ischemic" 24952884 miR-146a and miR-196a2 polymorphisms in patients with ischemic stroke in the northern Chinese Han population. genetics_GWAS hsa-mir-196a-2 "Diabetes Mellitus, Type 2" 24972764 Our findings suggest that miRNA-196a2 T/C polymorphism (rs11614913) is associated with an increased risk of CVD in type 2 diabetes patients. This provides further insights on pathogenesis of cardiovascular disease in type 2 diabetes patients. genetics_GWAS hsa-mir-132 Gastric Neoplasms 24981235 "A functional variant at miR-132-3p, miR-212-3p, and miR-361-5p binding site in CD80 gene alters susceptibility to gastric cancer in a Chinese Han population." genetics_GWAS hsa-mir-212 Gastric Neoplasms 24981235 "A functional variant at miR-132-3p, miR-212-3p, and miR-361-5p binding site in CD80 gene alters susceptibility to gastric cancer in a Chinese Han population." genetics_GWAS hsa-mir-361 Gastric Neoplasms 24981235 "A functional variant at miR-132-3p, miR-212-3p, and miR-361-5p binding site in CD80 gene alters susceptibility to gastric cancer in a Chinese Han population." genetics_GWAS hsa-mir-410 Stroke 24990426 "We report a novel association between a microRNA target site variant and stroke incidence, which is modulated by diet in terms of decreasing triglycerides and possibly stroke risk in rs13702 C allele carriers after a high-unsaturated fat MedDiet intervention." genetics_GWAS hsa-mir-125a Autoimmune Thyroiditis 24990808 Associations of single nucleotide polymorphisms in precursor-microRNA (miR)-125a and the expression of mature miR-125a with the development and prognosis of autoimmune thyroid diseases. genetics_GWAS hsa-mir-122 "Carcinoma, Hepatocellular" 24995424 A genetic variant in microRNA-122 regulatory region confers risk for chronic hepatitis B virus infection and hepatocellular carcinoma in Han Chinese. genetics_GWAS hsa-mir-485 Breast Neoplasms 25003827 miR-485-5p binding site SNP rs8752 in HPGD gene is associated with breast cancer risk. genetics_GWAS hsa-mir-137 Schizophrenia 25044277 The miR-137 schizophrenia susceptibility variant rs1625579 does not predict variability in brain volume in a sample of schizophrenic patients and healthy individuals. genetics_GWAS hsa-mir-146a Coronary Restenosis 25053223 we found a negative association for the G/C (P = 0.007) and a positive association for the C/C genotype with the risk of restenosis genetics_GWAS hsa-mir-149 "Carcinoma, Hepatocellular" 25061729 Association of miR-149C>T and miR-500A>G polymorphisms with the risk of hepatocellular carcinoma in the Chinese population. genetics_GWAS hsa-mir-499a "Carcinoma, Hepatocellular" 25061729 Association of miR-149C>T and miR-499A>G polymorphisms with the risk of hepatocellular carcinoma in the Chinese population. genetics_GWAS hsa-mir-26a Neurodegenerative Diseases [unspecific] 25074322 A functional SNP catalog of overlapping miRNA-binding sites in genes implicated in prion disease and other neurodegenerative disorders. genetics_GWAS hsa-mir-146a Lung Neoplasms 25077922 Effects of four single nucleotide polymorphisms in microRNA-coding genes on lung cancer risk. genetics_GWAS hsa-mir-149 Lung Neoplasms 25077922 Effects of four single nucleotide polymorphisms in microRNA-coding genes on lung cancer risk. genetics_GWAS hsa-mir-196a-2 Lung Neoplasms 25077922 Effects of four single nucleotide polymorphisms in microRNA-coding genes on lung cancer risk. genetics_GWAS hsa-mir-499b Lung Neoplasms 25077922 Effects of four single nucleotide polymorphisms in microRNA-coding genes on lung cancer risk. genetics_GWAS hsa-mir-27a Colorectal Carcinoma 25078482 Association between miR-27a genetic variants and susceptibility to colorectal cancer. genetics_GWAS hsa-mir-146a Prostate Neoplasms 25084752 Association between genetic variant in hsa-miR-146a gene and prostate cancer progression genetics_GWAS hsa-mir-146a Colorectal Carcinoma 25103961 "Lack of association between miR-27a, miR-146a, miR-196a-2, miR-492 and miR-608 gene polymorphisms and colorectal cancer." genetics_GWAS hsa-mir-196a-2 Colorectal Carcinoma 25103961 "Lack of association between miR-27a, miR-146a, miR-196a-2, miR-492 and miR-608 gene polymorphisms and colorectal cancer." genetics_GWAS hsa-mir-27a Colorectal Carcinoma 25103961 "Lack of association between miR-27a, miR-146a, miR-196a-2, miR-492 and miR-608 gene polymorphisms and colorectal cancer." genetics_GWAS hsa-mir-125a Gastric Neoplasms 25109760 "In this study, we found that a germline mutation in the miR-125a coding region is associated with human gastric cancer." genetics_GWAS hsa-mir-146a Lung Neoplasms 25154761 MicroRNA-146a rs2910164 polymorphism is associated with susceptibility to non-small cell lung cancer in the Chinese population. genetics_GWAS hsa-mir-502 "Carcinoma, Cervical" 25169478 "These data suggest that there are significant associations between the miR-502-binding site SNP in the 3'-UTR of SET8 and the TP53 codon 72 polymorphism with cervical cancer in Chinese, and there is a gene-gene interaction." genetics_GWAS hsa-mir-646 "Carcinoma, Hepatocellular" 25177719 Our findings support the view that the miR-646 SNP rs6513497 may contribute to the susceptibility of HCC. genetics_GWAS hsa-mir-34a "Carcinoma, Hepatocellular" 25179842 A functional variant at miR-34a binding site in toll-like receptor 4 gene alters susceptibility to hepatocellular carcinoma in a Chinese Han population. genetics_GWAS hsa-mir-146a Leprosy 25187983 Pre-miR-146a (rs2910164 G>C) single nucleotide polymorphism is genetically and functionally associated with leprosy. genetics_GWAS hsa-mir-34b Neoplasms [unspecific] 25190019 The genetic association between pri-miR-34b/c polymorphism (rs4938723 T>C) and susceptibility to cancers: evidence from published studies. genetics_GWAS hsa-mir-34c Neoplasms [unspecific] 25190019 The genetic association between pri-miR-34b/c polymorphism (rs4938723 T>C) and susceptibility to cancers: evidence from published studies. genetics_GWAS hsa-mir-34b Gastric Neoplasms 25190020 Promoter polymorphisms of miR-34b/c are associated with risk of gastric cancer in a Chinese population. genetics_GWAS hsa-mir-34c Gastric Neoplasms 25190020 Promoter polymorphisms of miR-34b/c are associated with risk of gastric cancer in a Chinese population. genetics_GWAS hsa-mir-1 Coronary Artery Disease 25197382 Polymorphism in miRNA-1 target site and circulating miRNA-1 phenotype are associated with the decreased risk and prognosis of coronary artery disease. genetics_GWAS hsa-mir-146a Psoriasis 25209759 A single-nucleotide polymorphism of miR-146a and psoriasis: an association and functional study. genetics_GWAS hsa-mir-146a Systemic Lupus Erythematosus 25218914 "The present meta-analysis suggests important roles for the mir-499 rs3746444 polymorphism in RA, especially in the Caucasian population and for miR-146a rs57095329 polymorphism in SLE." genetics_GWAS hsa-mir-149 "Carcinoma, Hepatocellular" 25222224 Role of miR-149C>T polymorphisms on the risk of hepatocellular carcinoma in a Chinese population. genetics_GWAS hsa-mir-27a Colorectal Carcinoma 25222241 Association between a functional variant in microRNA-27a and susceptibility to colorectal cancer in a Chinese Han population. genetics_GWAS hsa-mir-137 Schizophrenia 25241074 Lack of association between microRNA-137 SNP rs1625579 and schizophrenia in a replication study of Han Chinese. genetics_GWAS hsa-mir-4513 Coronary Artery Disease 25256095 "A genetic variant in the seed region of miR-4513 shows pleiotropic effects on lipid and glucose homeostasis, blood pressure, and coronary artery disease." genetics_GWAS hsa-mir-146a Arthritis 25269878 This meta-analysis suggests that the miR-499 rs374644 and IRAKI rs3027898 polymorphisms are associated with susceptibility to inflammatory arthritis. genetics_GWAS hsa-mir-499 Arthritis 25269878 This meta-analysis suggests that the miR-499 rs374644 and IRAKI rs3027898 polymorphisms are associated with susceptibility to inflammatory arthritis. genetics_GWAS hsa-mir-146a Colorectal Carcinoma 25283877 Effect of a common genetic variant microRNA-146a rs2910164 on colorectal cancer: a meta-analysis. genetics_GWAS hsa-mir-146a Generalized Epilepsy with Febrile Seizures Plus 25319229 Association of genetic polymorphism of pre-microRNA-146a rs2910164 and serum high-mobility group box 1 with febrile seizures in Egyptian children. genetics_GWAS hsa-mir-146a Gastric Neoplasms 25326754 The present meta-analysis suggests an increased risk between miR-146a rs2910164 GG genotype and gastric cancer susceptibility in Chinese based on published literatures. genetics_GWAS hsa-mir-218 "Squamous Cell Carcinoma, Esophageal" 25337271 The impact of pri-miR-218 rs11134527 on the risk and prognosis of patients with esophageal squamous cell carcinoma. genetics_GWAS hsa-mir-502 "Lymphoma, Non-Hodgkin" 25343552 the SNP in the miRNA binding site of the SET8 3'-untranslated region seems to influence survival of NHL. It may have possible prognostic and survival value in the clinic. genetics_GWAS hsa-mir-143 Prostate Neoplasms 25354797 there is the significant association between the functional promoter variant rs4705342T>C in miR-143 and PCa risk genetics_GWAS hsa-mir-518 Premature Ovarian Failure 25365407 "Association study of TGFBR2 and miR-518 gene polymorphisms with age at natural menopause, premature ovarian failure, and early menopause among Chinese Hanwomen." genetics_GWAS hsa-mir-146a "Lymphoma, B-Cell" 25370733 MicroRNA-146a rs2910164 polymorphism and the risk of diffuse large B cell lymphoma in the Chinese Han population. genetics_GWAS hsa-mir-184 "Squamous Cell Carcinoma, Esophageal" 25383966 Our data demonstrate that functional TNFAIP2 rs8126 genetic variant is a ESCC susceptibility SNP. genetics_GWAS hsa-mir-146a Gastric Neoplasms 25386093 "The miR-146a rs2910164 polymorphism is associated with increased gastric cancer risk, particularly evident in high quality studies with small sample sized Caucasian populations." genetics_GWAS hsa-mir-27a Gastric Neoplasms 25399405 rs895819 and rs11671784 inversely affect gastric cancer risk and the influence was closely related to their effects on miR-27a expression. genetics_GWAS hsa-mir-148a Gastric Neoplasms 25399950 the SCRN1 rs6976789 polymorphism may play an important role in the GC development and progression. genetics_GWAS hsa-mir-149 Thyroid Neoplasms 25405731 "Rs2292832 was possibly involved in the susceptibility and local progression of PTC in Chinese patients, by altering the expression level of mir-149-5p and its target genes." genetics_GWAS hsa-mir-604 "Carcinoma, Hepatocellular" 25408584 "The T allele at miR-604 rs2368392 may be a risk allele for the chronicity of HBV infection, but may be a protective allele for the progression to HCC in chronic HBV carriers." genetics_GWAS hsa-mir-499 Neoplasms [unspecific] 25433484 "hsa-mir-499 rs3746444 T > C polymorphism is associated with the risk of cancer in Asians, mainly in Iranian and Chinese population. However, rs3746444 T > C polymorphism is negatively associated with the risk of esophageal cancer." genetics_GWAS hsa-mir-137 Schizophrenia 25434007 "rare noncoding risk variants are associated with SZ and BP at MIR137/MIR2682 locus, with risk alleles decreasing MIR137/MIR2682 expression." genetics_GWAS hsa-mir-2682 Schizophrenia 25434007 "rare noncoding risk variants are associated with SZ and BP at MIR137/MIR2682 locus, with risk alleles decreasing MIR137/MIR2682 expression." genetics_GWAS hsa-mir-611 Pleural Mesothelioma 25436799 MRP performance as diagnostic biomarker improved by considering the genotype rs1057147. This polymorphism most likely affects a binding site for miR-611. genetics_GWAS hsa-mir-146a Hirschsprung Disease 25445498 "the polymorphism rs2910164 in pre-miR-146a might alter the production of mature miR-146a and then down-regulate the target gene ROBO1, which plays an important role in pathogenesis of HSCR." genetics_GWAS hsa-mir-146a Gastric Neoplasms 25455160 "miR-146a rs2910164 polymorphism was associated with the susceptibility to gastric cancer, especially in Asian population." genetics_GWAS hsa-mir-34b Colorectal Carcinoma 25475831 rs4938723 was a susceptible locus only for hepatocellular cancer and colorectal cancer. genetics_GWAS hsa-mir-34c Colorectal Carcinoma 25475831 rs4938723 was a susceptible locus only for hepatocellular cancer and colorectal cancer. genetics_GWAS hsa-mir-196a "Lymphoma, Non-Hodgkin" 25501512 the miR-196a2 polymorphism may increase the risk of NHL by altering the expression of mature miR-196a. genetics_GWAS hsa-mir-146a Lung Neoplasms 25524943 mir-196a2 SNP influences the susceptibility of lung cancer. Mir-146a and mir-149 SNP do not play a role in lung cancer risk. These findings need more validation by larger studies. genetics_GWAS hsa-mir-149 Lung Neoplasms 25524943 mir-196a2 SNP influences the susceptibility of lung cancer. Mir-146a and mir-149 SNP do not play a role in lung cancer risk. These findings need more validation by larger studies. genetics_GWAS hsa-mir-196a-2 Lung Neoplasms 25524943 mir-196a2 SNP influences the susceptibility of lung cancer. Mir-146a and mir-149 SNP do not play a role in lung cancer risk. These findings need more validation by larger studies. genetics_GWAS hsa-mir-34a Parkinson Disease 25541488 "down-regulation of miR-34b and miR-34c in the brain, as well as an SNP in the 3'-UTR of ¦Á-syn can increase ¦Á-syn expression, possibly contributing to PD pathogenesis." genetics_GWAS hsa-mir-146a "Carcinoma, Hepatocellular" 25546664 "the miR-146a rs2910164 polymorphism contributes to increased HCC susceptibility, especially in Asian populations. Further large and well-designed studies are required to validate this association." genetics_GWAS hsa-mir-196a-2 "Carcinoma, Hepatocellular" 25546664 "the miR-146a rs2910165 polymorphism contributes to increased HCC susceptibility, especially in Asian populations. Further large and well-designed studies are required to validate this association." genetics_GWAS hsa-mir-146a Digestive System Neoplasms 25555557 "digestive tract neoplasms might associate with miR-146a variants, but not miR-196a2 variants" genetics_GWAS hsa-mir-196a Digestive System Neoplasms 25555557 "digestive tract neoplasms might associate with miR-146a variants, but not miR-196a2 variants" genetics_GWAS hsa-mir-27a Breast Neoplasms 25556434 an association between pre-miR-27a polymorphism rs895819 and cancer risk in Caucasians. The protective effect of rs895819 [G] allele in younger breast cancer and in the group of unilateral breast cancer patients await further confirmation since the included studies in this meta-analysis were limited. genetics_GWAS hsa-mir-320b Coronary Artery Disease 25573129 "The common SNP (rs10916581) in the promoter region of pre-miR-320b-2 might have little contribution to the CHD predisposition in Chinese Han population, and it might not affect circulating miR-320b level. Conventional CHD risk factors (BMI, TC/HDL-C, hypertension and diabetes) might have effects on its circulating level." genetics_GWAS hsa-mir-146a Multiple Sclerosis 25591770 rs2910164 may play a role in MS susceptibility in females. The rs2910164 G>C variation may affect the expression of miR-146a and the release of proinflammatory cytokines. genetics_GWAS hsa-mir-499 Lung Neoplasms 25614447 "the rs3746444T>C polymorphism in mature miR-499 sequence could contribute to poor prognosis by modulating cancer-related genes' expression and thus involve tumorigenesis and anti-chemotherapy, which may be a useful biomarker to predict lung cancer patients' prognosis." genetics_GWAS hsa-mir-208b "Cardiomyopathy, Hypertrophic" 25633875 Sequence variants in miRNAs of patients with HCM are not frequent and the contribution of these variants to the development of this disease was not demonstrated. genetics_GWAS hsa-mir-367 "Cardiomyopathy, Hypertrophic" 25633875 Sequence variants in miRNAs of patients with HCM are not frequent and the contribution of these variants to the development of this disease was not demonstrated. genetics_GWAS hsa-mir-499 Neoplasms [unspecific] 25640376 hsa-mir-499 rs3746444 A>G polymorphism is not associated with risk of cancer based on current evidence. genetics_GWAS hsa-mir-146a "Tuberculosis, Pulmonary" 25650003 "Association of the miR-146a, miR-149, miR-196a2 and miR-499 polymorphisms with susceptibility to pulmonary tuberculosis in the Chinese Uygur, Kazak and Southern Han populations." genetics_GWAS hsa-mir-149 "Tuberculosis, Pulmonary" 25650003 "Association of the miR-146a, miR-149, miR-196a2 and miR-499 polymorphisms with susceptibility to pulmonary tuberculosis in the Chinese Uygur, Kazak and Southern Han populations." genetics_GWAS hsa-mir-196a-2 "Tuberculosis, Pulmonary" 25650003 "Association of the miR-146a, miR-149, miR-196a2 and miR-499 polymorphisms with susceptibility to pulmonary tuberculosis in the Chinese Uygur, Kazak and Southern Han populations." genetics_GWAS hsa-mir-499 "Tuberculosis, Pulmonary" 25650003 "Association of the miR-146a, miR-149, miR-196a2 and miR-499 polymorphisms with susceptibility to pulmonary tuberculosis in the Chinese Uygur, Kazak and Southern Han populations." genetics_GWAS hsa-mir-34b Gastric Neoplasms 25658980 rs4938723 polymorphism is associated with a decreased risk of gastric cancer. genetics_GWAS hsa-mir-34c Gastric Neoplasms 25658980 rs4938723 polymorphism is associated with a decreased risk of gastric cancer. genetics_GWAS hsa-mir-29c Gastric Neoplasms 25661340 A miR-29c binding site genetic variant in the 3'-untranslated region of LAMTOR3 gene is associated with gastric cancer risk. genetics_GWAS hsa-mir-17 Osteosarcoma 25663449 "This study suggests that SNPs in RISC complex genes may be involved in osteosarcoma susceptibility, especially rs11866002 in CNOT1." genetics_GWAS hsa-mir-18 Osteosarcoma 25663449 "This study suggests that SNPs in RISC complex genes may be involved in osteosarcoma susceptibility, especially rs11866002 in CNOT1." genetics_GWAS hsa-mir-19a Osteosarcoma 25663449 "This study suggests that SNPs in RISC complex genes may be involved in osteosarcoma susceptibility, especially rs11866002 in CNOT1." genetics_GWAS hsa-mir-19b-1 Osteosarcoma 25663449 "This study suggests that SNPs in RISC complex genes may be involved in osteosarcoma susceptibility, especially rs11866002 in CNOT1." genetics_GWAS hsa-mir-20a Osteosarcoma 25663449 "This study suggests that SNPs in RISC complex genes may be involved in osteosarcoma susceptibility, especially rs11866002 in CNOT1." genetics_GWAS hsa-mir-92-1 Osteosarcoma 25663449 "This study suggests that SNPs in RISC complex genes may be involved in osteosarcoma susceptibility, especially rs11866002 in CNOT1." genetics_GWAS hsa-mir-124a "Diabetes Mellitus, Type 2" 25673459 "Affection of single-nucleotide polymorphisms in miR-27a, miR-124a, and miR-146a on susceptibility to type 2 diabetes mellitus in Chinese Han people." genetics_GWAS hsa-mir-146a "Diabetes Mellitus, Type 2" 25673459 "Affection of single-nucleotide polymorphisms in miR-27a, miR-124a, and miR-146a on susceptibility to type 2 diabetes mellitus in Chinese Han people." genetics_GWAS hsa-mir-27a "Diabetes Mellitus, Type 2" 25673459 "Affection of single-nucleotide polymorphisms in miR-27a, miR-124a, and miR-146a on susceptibility to type 2 diabetes mellitus in Chinese Han people." genetics_GWAS hsa-mir-155 "Lymphoma, Large B-Cell, Diffuse" 25677902 "the miRs expression in B-NHLs[11q] provides a new suggestion, in addition to pathomorphological and clinical similarities between classical, i.e.,MYC translocation-positive BL, and B-NHLs[11q], to recognize the B-NHLs[11q] subgroup of DLBCL/BL category as a MYC translocation-negative variant of BL in most cases, and points to the potential utility of miR-155/BIC/miR-21/miR-26a for the differential diagnosis of a heterogeneous category of DLBCL/BL." genetics_GWAS hsa-mir-21 "Lymphoma, Large B-Cell, Diffuse" 25677902 "the miRs expression in B-NHLs[11q] provides a new suggestion, in addition to pathomorphological and clinical similarities between classical, i.e.,MYC translocation-positive BL, and B-NHLs[11q], to recognize the B-NHLs[11q] subgroup of DLBCL/BL category as a MYC translocation-negative variant of BL in most cases, and points to the potential utility of miR-155/BIC/miR-21/miR-26a for the differential diagnosis of a heterogeneous category of DLBCL/BL." genetics_GWAS hsa-mir-26a "Lymphoma, Large B-Cell, Diffuse" 25677902 "the miRs expression in B-NHLs[11q] provides a new suggestion, in addition to pathomorphological and clinical similarities between classical, i.e.,MYC translocation-positive BL, and B-NHLs[11q], to recognize the B-NHLs[11q] subgroup of DLBCL/BL category as a MYC translocation-negative variant of BL in most cases, and points to the potential utility of miR-155/BIC/miR-21/miR-26a for the differential diagnosis of a heterogeneous category of DLBCL/BL." genetics_GWAS hsa-mir-17 Breast Neoplasms 25680407 Association of microRNA 17-92 cluster host gene (MIR17HG) polymorphisms with breast cancer. genetics_GWAS hsa-mir-18 Breast Neoplasms 25680407 Association of microRNA 17-92 cluster host gene (MIR17HG) polymorphisms with breast cancer. genetics_GWAS hsa-mir-19a Breast Neoplasms 25680407 Association of microRNA 17-92 cluster host gene (MIR17HG) polymorphisms with breast cancer. genetics_GWAS hsa-mir-19b-1 Breast Neoplasms 25680407 Association of microRNA 17-92 cluster host gene (MIR17HG) polymorphisms with breast cancer. genetics_GWAS hsa-mir-20a Breast Neoplasms 25680407 Association of microRNA 17-92 cluster host gene (MIR17HG) polymorphisms with breast cancer. genetics_GWAS hsa-mir-92-1 Breast Neoplasms 25680407 Association of microRNA 17-92 cluster host gene (MIR17HG) polymorphisms with breast cancer. genetics_GWAS hsa-mir-605 Li-Fraumeni Syndrome 25683625 A functional variant in miR-605 modifies the age of onset in Li-Fraumeni syndrome. genetics_GWAS hsa-mir-3162 Prostate Neoplasms 25691096 "Findings from this large association study suggest that a focus on miRSNPs, including functional evaluation, can identify candidate risk loci below currently accepted statistical levels of genome-wide significance. Studies of miRNAs and their interactions with SNPs could provide further insights into the mechanisms of prostate cancer risk." genetics_GWAS hsa-mir-370 Prostate Neoplasms 25691096 "Findings from this large association study suggest that a focus on miRSNPs, including functional evaluation, can identify candidate risk loci below currently accepted statistical levels of genome-wide significance. Studies of miRNAs and their interactions with SNPs could provide further insights into the mechanisms of prostate cancer risk." genetics_GWAS hsa-mir-146a Gastrointestinal Neoplasms 25693929 "No significant association between miR-146a rs2910164G/C polymorphism and gastrointestinal cancer susceptibility was found in this meta-analysis. But for homozygous model, people with GG genotype may have increased risk of developing colorectal cancer." genetics_GWAS hsa-mir-17 "Carcinoma, Lung, Non-Small-Cell" 25716425 The rs3660G>C affects KRT81 expression and thus influences survival in early-stage NSCLC. The analysis of the rs3660G>C polymorphism may be useful to identify patients at high risk of a poor disease outcome. genetics_GWAS hsa-mir-20b "Carcinoma, Lung, Non-Small-Cell" 25716425 The rs3660G>C affects KRT81 expression and thus influences survival in early-stage NSCLC. The analysis of the rs3660G>C polymorphism may be useful to identify patients at high risk of a poor disease outcome. genetics_GWAS hsa-mir-146a Chronic Obstructive Pulmonary Disease 25767384 "the rs2910164 CC and GC genotype was found to be associated with an improved lung function and milder disease stages, at least partially, mediated by its ability to increase in COX2 expression and PGE2 production." genetics_GWAS hsa-mir-146b Psychiatric Disorders 25771167 Our findings highlight trans effects of common variants on microRNA-mediated gene expression as an integral part of the genetic architecture of complex disorders and traits. genetics_GWAS hsa-mir-107 "Adenocarcinoma, Gastric" 25771723 miR-107 is dysregulated in GAC pathogenesis and the SNP rs2296616 may play a role in the process. genetics_GWAS hsa-mir-1206 "Leukemia, Lymphocytic, Chronic, B-Cell" 25793711 These findings suggest that polymorphisms in genes involved in miRNAs biogenesis pathway as well as in pre-miRNAs contribute to the risk of CLL. Large-scale studies are needed to validate the current findings. genetics_GWAS hsa-mir-196a-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 25793711 These findings suggest that polymorphisms in genes involved in miRNAs biogenesis pathway as well as in pre-miRNAs contribute to the risk of CLL. Large-scale studies are needed to validate the current findings. genetics_GWAS hsa-mir-146a Gastric Neoplasms 25795117 miR-27a rs895819 and miR-149 rs2292832 are of potential forewarning ability for gastric cancer risk. genetics_GWAS hsa-mir-149 Gastric Neoplasms 25795117 miR-27a rs895819 and miR-149 rs2292832 are of potential forewarning ability for gastric cancer risk. genetics_GWAS hsa-mir-196a-2 Gastric Neoplasms 25795117 miR-27a rs895819 and miR-149 rs2292832 are of potential forewarning ability for gastric cancer risk. genetics_GWAS hsa-mir-27a Gastric Neoplasms 25795117 miR-27a rs895819 and miR-149 rs2292832 are of potential forewarning ability for gastric cancer risk. genetics_GWAS hsa-mir-499 Gastric Neoplasms 25795117 miR-27a rs895819 and miR-149 rs2292832 are of potential forewarning ability for gastric cancer risk. genetics_GWAS hsa-mir-548ac Multiple Sclerosis 25795118 Susceptibility variants in the CD58 gene locus point to a role of microRNA-548ac in the pathogenesis of multiple sclerosis. genetics_GWAS hsa-mir-5481 Glaucoma 25809640 These data support the role of hsa-miR-548l as a regulator of FOXC1 translation and provide evidence for the c.*734A>T variant as a modifier factor for the activity of coding glaucoma-associated FOXC1 mutations. genetics_GWAS hsa-mir-320e Cardiometabolic Disorders 25814643 We provide evidence for a model in which polymorphisms in miRNA-binding sites can both positively and negatively affect miRNA-mediated regulation of cardiometabolic genes. genetics_GWAS hsa-mir-146a Autoimmune Diseases [unspecific] 25830862 MiR-146a rs2910164 G>C polymorphism was associated with the susceptibility of ADs. genetics_GWAS hsa-mir-520a Colorectal Carcinoma 25834816 A functional variant at miR-520a binding site in PIK3CA alters susceptibility to colorectal cancer in a Chinese Han population. genetics_GWAS hsa-mir-146a Ankylosing Spondylitis 25836258 Association between ankylosing spondylitis and the miR-146a and miR-499 polymorphisms. genetics_GWAS hsa-mir-499 Ankylosing Spondylitis 25836258 Association between ankylosing spondylitis and the miR-146a and miR-499 polymorphisms. genetics_GWAS hsa-mir-124-1 Neuropsychiatric Disorders [unspecific] 25841663 We showed for the first time the association of a functional polymorphism in MIR124-1 and aggressiveness. Known targets of miR-124 (such as BDNF and DRD4 genes) could explain the effect of this miRNA on behavior. A future analysis of additional novel functional polymorphisms in other brain expressed miRNAs could be useful for a deeper understanding of aggression in humans. genetics_GWAS hsa-mir-608 "Carcinoma, Nasopharyngeal" 25861865 Polymorphism in mature microRNA-608 sequence is associated with an increased risk of nasopharyngeal carcinoma. genetics_GWAS hsa-mir-146a Cardiovascular Diseases [unspecific] 25865299 Association of miR-146a rs2910164 polymorphism with cardio-cerebrovascular diseases: A systematic review and meta-analysis. genetics_GWAS hsa-mir-499 "Carcinoma, Hepatocellular" 25867338 "subjects carrying the miR-499 A allele showed a greatly increased risk of HCC in subjects infected with HBV compared with subjects carrying the miR-499 A allele, with an adjusted odds ratio (95% confidence interval) of 1.53 (1.34-2.41). In conclusion, the miR-146aG>C and miR-499A>G polymorphisms do not have a role in the genetic susceptibility to HCC." genetics_GWAS hsa-mir-146a Epilepsy 25891929 Our data indicate that the rs57095329 polymorphism in the promoter region of miR-146a is involved in the genetic susceptibility to DRE and the seizures frequency. genetics_GWAS hsa-mir-196a-2 Vitiligo 25896941 miR-196a-2 rs11614913 polymorphism is associated with vitiligo by affecting heterodimeric molecular complexes of Tyr and Tyrp1. genetics_GWAS hsa-mir-137 Schizophrenia 25921703 "The impact of genome wide supported microRNA-137 (MIR137) risk variants on frontal and striatal white matter integrity, neurocognitive functioning, and negative symptoms in schizophrenia." genetics_GWAS hsa-mir-122 "Squamous Cell Carcinoma, Cerevial" 25955681 These findings indicate that the IL1A rs3783553 polymorphism may be associated with the etiology of CSCC. genetics_GWAS hsa-mir-146a Metabolic Syndrome 25958310 The C allele of miRNA-146a rs2910164 showed positive association with increased susceptibility to metabolic syndrome and its phenotypes in the study population. genetics_GWAS hsa-let-7c Hepatitis B Virus Infection 25966251 "The meta-analysis results indicated that the miR-196a-2*T,miR-122*del, miR-106b-25*A, and miR-let-7c*del alleles/carriers increase the risk of hepatitis B among the Asian population. However, the miR-146a, miR- 499,miR-149, miR-218, and miR-34b/c polymorphisms may not be linked with the risk of hepatitis B. Further investigations are warranted to determine the exact associations between microRNA mutations and hepatitis B susceptibility." genetics_GWAS hsa-mir-106b Hepatitis B Virus Infection 25966251 "The meta-analysis results indicated that the miR-196a-2*T,miR-122*del, miR-106b-25*A, and miR-let-7c*del alleles/carriers increase the risk of hepatitis B among the Asian population. However, the miR-146a, miR- 499,miR-149, miR-218, and miR-34b/c polymorphisms may not be linked with the risk of hepatitis B. Further investigations are warranted to determine the exact associations between microRNA mutations and hepatitis B susceptibility." genetics_GWAS hsa-mir-122 Hepatitis B Virus Infection 25966251 "The meta-analysis results indicated that the miR-196a-2*T,miR-122*del, miR-106b-25*A, and miR-let-7c*del alleles/carriers increase the risk of hepatitis B among the Asian population. However, the miR-146a, miR- 499,miR-149, miR-218, and miR-34b/c polymorphisms may not be linked with the risk of hepatitis B. Further investigations are warranted to determine the exact associations between microRNA mutations and hepatitis B susceptibility." genetics_GWAS hsa-mir-146a Hepatitis B Virus Infection 25966251 "The meta-analysis results indicated that the miR-196a-2*T,miR-122*del, miR-106b-25*A, and miR-let-7c*del alleles/carriers increase the risk of hepatitis B among the Asian population. However, the miR-146a, miR- 499,miR-149, miR-218, and miR-34b/c polymorphisms may not be linked with the risk of hepatitis B. Further investigations are warranted to determine the exact associations between microRNA mutations and hepatitis B susceptibility." genetics_GWAS hsa-mir-149 Hepatitis B Virus Infection 25966251 "The meta-analysis results indicated that the miR-196a-2*T,miR-122*del, miR-106b-25*A, and miR-let-7c*del alleles/carriers increase the risk of hepatitis B among the Asian population. However, the miR-146a, miR- 499,miR-149, miR-218, and miR-34b/c polymorphisms may not be linked with the risk of hepatitis B. Further investigations are warranted to determine the exact associations between microRNA mutations and hepatitis B susceptibility." genetics_GWAS hsa-mir-196a-2 Hepatitis B Virus Infection 25966251 "The meta-analysis results indicated that the miR-196a-2*T,miR-122*del, miR-106b-25*A, and miR-let-7c*del alleles/carriers increase the risk of hepatitis B among the Asian population. However, the miR-146a, miR- 499,miR-149, miR-218, and miR-34b/c polymorphisms may not be linked with the risk of hepatitis B. Further investigations are warranted to determine the exact associations between microRNA mutations and hepatitis B susceptibility." genetics_GWAS hsa-mir-218 Hepatitis B Virus Infection 25966251 "The meta-analysis results indicated that the miR-196a-2*T,miR-122*del, miR-106b-25*A, and miR-let-7c*del alleles/carriers increase the risk of hepatitis B among the Asian population. However, the miR-146a, miR- 499,miR-149, miR-218, and miR-34b/c polymorphisms may not be linked with the risk of hepatitis B. Further investigations are warranted to determine the exact associations between microRNA mutations and hepatitis B susceptibility." genetics_GWAS hsa-mir-34b Hepatitis B Virus Infection 25966251 "The meta-analysis results indicated that the miR-196a-2*T,miR-122*del, miR-106b-25*A, and miR-let-7c*del alleles/carriers increase the risk of hepatitis B among the Asian population. However, the miR-146a, miR- 499,miR-149, miR-218, and miR-34b/c polymorphisms may not be linked with the risk of hepatitis B. Further investigations are warranted to determine the exact associations between microRNA mutations and hepatitis B susceptibility." genetics_GWAS hsa-mir-34c Hepatitis B Virus Infection 25966251 "The meta-analysis results indicated that the miR-196a-2*T,miR-122*del, miR-106b-25*A, and miR-let-7c*del alleles/carriers increase the risk of hepatitis B among the Asian population. However, the miR-146a, miR- 499,miR-149, miR-218, and miR-34b/c polymorphisms may not be linked with the risk of hepatitis B. Further investigations are warranted to determine the exact associations between microRNA mutations and hepatitis B susceptibility." genetics_GWAS hsa-mir-499 Hepatitis B Virus Infection 25966251 "The meta-analysis results indicated that the miR-196a-2*T,miR-122*del, miR-106b-25*A, and miR-let-7c*del alleles/carriers increase the risk of hepatitis B among the Asian population. However, the miR-146a, miR- 499,miR-149, miR-218, and miR-34b/c polymorphisms may not be linked with the risk of hepatitis B. Further investigations are warranted to determine the exact associations between microRNA mutations and hepatitis B susceptibility." genetics_GWAS hsa-mir-27a Colorectal Carcinoma 25976406 miR-27a rs895819 polymorphism was associated with increased risk of colorectal cancer in Chinese population. genetics_GWAS hsa-mir-122 Oral Neoplasms 25981582 "These results suggest that IL-1¦Á 3' UTR rs3783553 polymorphism may be functional and influence susceptibility to HPV16-associated OSCC, particularly for SCCOP. Validation of our findings is warranted." genetics_GWAS hsa-mir-21 "Carcinoma, Cervical" 25987069 E6D25E of the HPV16As variant differed from the E6 prototype in its activities on epigenetic modulation and immune surveillance and this might be a key factor for the important role of this variant in cervical cancer progression. genetics_GWAS hsa-mir-214 Gastric Neoplasms 25998065 "Our data suggested that rs114673809, which is located at the miR-214 binding site in the 3'-UTR of MTHFR, may play an important role in the development of gastric cancer in a Chinese Han population." genetics_GWAS hsa-mir-146a Endometrial Neoplasms 26008204 "Association of SNPs in miR-146a, miR-196a2, and miR-499 with the risk of endometrial/ovarian cancer." genetics_GWAS hsa-mir-196a-2 Endometrial Neoplasms 26008204 "Association of SNPs in miR-146a, miR-196a2, and miR-499 with the risk of endometrial/ovarian cancer." genetics_GWAS hsa-mir-499 Endometrial Neoplasms 26008204 "Association of SNPs in miR-146a, miR-196a2, and miR-499 with the risk of endometrial/ovarian cancer." genetics_GWAS hsa-mir-509 Colorectal Carcinoma 26010608 These findings suggest that the rs13347C/T in microRNA binding site may be potential biomarkers for genetic susceptibility to CRC. genetics_GWAS hsa-mir-149 Rheumatoid Arthritis 26032077 "SNP rs22928323 in miR-149 is correlated with RA in the east of Chinese Han population, whereas there is no correlation between miR-149 polymorphism and clinical characteristics in patients with RA." genetics_GWAS hsa-mir-146a Behcet Disease 26053525 Association of Pre-miRNA-499 rs3746444 and Pre-miRNA-146a rs2910164 Polymorphisms and Susceptibility to Behcet's Disease. genetics_GWAS hsa-mir-499 Behcet Disease 26053525 Association of Pre-miRNA-499 rs3746444 and Pre-miRNA-146a rs2910164 Polymorphisms and Susceptibility to Behcet's Disease. genetics_GWAS hsa-mir-4293 "Squamous Cell Carcinoma, Esophageal" 26055141 miR-449b rs10061133 and miR-4293 rs12220909 polymorphisms are associated with decreased esophageal squamous cell carcinoma in a Chinese population. genetics_GWAS hsa-mir-449b "Squamous Cell Carcinoma, Esophageal" 26055141 miR-449b rs10061133 and miR-4293 rs12220909 polymorphisms are associated with decreased esophageal squamous cell carcinoma in a Chinese population. genetics_GWAS hsa-mir-155 Melanoma 26068396 Polymorphisms in 3'UTR of TYRP1 mRNA can affect TYRP1 mRNA regulation by miR-155 and its subsequent translation into protein. These SNPs can render TYRP1 mRNA and protein expression nonsusceptible to miR-155 activity and disclose a prognostic value for TYRP1 protein in a subgroup of melanoma patients. These data support the interest in the prognostic value of melanogenic markers and propose TYRP1 to refine prognosis in patients with advanced disease. genetics_GWAS hsa-mir-146a Lung Neoplasms 26083623 The interactions between miRNA SNPs and cooking oil fume exposure suggested by ORs of different combination were not statistically significant. genetics_GWAS hsa-mir-196a-2 Lung Neoplasms 26083623 The interactions between miRNA SNPs and cooking oil fume exposure suggested by ORs of different combination were not statistically significant. genetics_GWAS hsa-mir-27a Lung Neoplasms 26083623 The interactions between miRNA SNPs and cooking oil fume exposure suggested by ORs of different combination were not statistically significant. genetics_GWAS hsa-mir-423 Lung Neoplasms 26083623 The interactions between miRNA SNPs and cooking oil fume exposure suggested by ORs of different combination were not statistically significant. genetics_GWAS hsa-mir-608 Lung Neoplasms 26083623 The interactions between miRNA SNPs and cooking oil fume exposure suggested by ORs of different combination were not statistically significant. genetics_GWAS hsa-mir-146a Alzheimer Disease 26095531 A single nucleotide polymorphism in primary-microRNA-146a reduces the expression of mature microRNA-146a in patients with Alzheimer's disease and is associated with the pathogenesis of Alzheimer's disease. genetics_GWAS hsa-mir-196a-2 Prostate Neoplasms 26112096 "Assessment of association between genetic variants in microRNA genes hsa-miR-499,hsa-miR-196a2 and hsa-miR-27a and prostate cancer risk in Serbian population." genetics_GWAS hsa-mir-27a Prostate Neoplasms 26112096 "Assessment of association between genetic variants in microRNA genes hsa-miR-499,hsa-miR-196a2 and hsa-miR-27a and prostate cancer risk in Serbian population." genetics_GWAS hsa-mir-499 Prostate Neoplasms 26112096 "Assessment of association between genetic variants in microRNA genes hsa-miR-499,hsa-miR-196a2 and hsa-miR-27a and prostate cancer risk in Serbian population." genetics_GWAS hsa-mir-146a Melanoma 26122011 Association of microRNA 146a polymorphism rs2910164 and the risk of melanoma in an Italian population. genetics_GWAS hsa-mir-196a-2 Breast Neoplasms 26125831 Our results suggested that miR-146a rs2910164 G>C and miR-196a2 rs11614913 T>C may be biomarkers for predicting breast cancer risk in the Chinese population. genetics_GWAS hsa-mir-3622a Colorectal Carcinoma 26147304 "Our results indicate variations in RAN rs14035, DICER1 rs3742330, XPO5 rs11077, and DROSHA rs10719 of Korean patients are significantly associated with their risk of CRC." genetics_GWAS hsa-mir-5582 Colorectal Carcinoma 26147304 "Our results indicate variations in RAN rs14035, DICER1 rs3742330, XPO5 rs11077, and DROSHA rs10719 of Korean patients are significantly associated with their risk of CRC." genetics_GWAS hsa-mir-125b Breast Neoplasms 26190157 Evaluation the susceptibility of five polymorphisms in microRNA-binding sites to female breast cancer risk in Chinese population. genetics_GWAS hsa-mir-320 Breast Neoplasms 26190157 Evaluation the susceptibility of five polymorphisms in microRNA-binding sites to female breast cancer risk in Chinese population. genetics_GWAS hsa-mir-367 Breast Neoplasms 26190157 Evaluation the susceptibility of five polymorphisms in microRNA-binding sites to female breast cancer risk in Chinese population. genetics_GWAS hsa-mir-570 Viral Infectious Disease 26199425 it was demonstrated that human CYP2E1 was regulated by miR-570 in a genotype-dependent manner. This report describes the first proof that SNP in 3'-UTR of human P450 affects binding of miRNA to modulate the expression in the liver. genetics_GWAS hsa-mir-146a Pulmonary Hypertension 26202355 "the results of this study demonstrate that the rs2910164 CC and GC genotype is associated with a decreased risk of pulmonary hypertension, which could be attributed to defective miRNA processing and compromised ability to inhibit production of COX-2 and PGI2." genetics_GWAS hsa-mir-146a Intracranial Aneurysm 26214448 Association between the hsa-miR-146a rs2910164 functional polymorphism with susceptibility to intracranial aneurysm. genetics_GWAS hsa-mir-146a "Squamous Cell Carcinoma, Oral" 26214637 "The miR-146a rs2910164 polymorphism is associated with increased risk for cervical and skin SCC. In contrast, rs2910164 in miR-146a is related to decreased risk for nasopharyngeal and oral SCC." genetics_GWAS hsa-mir-483 Colorectal Carcinoma 26235181 Both the single nucleotide polymorphism variants showed a positive association toward risk of lung cancer. genetics_GWAS hsa-mir-551a Colorectal Carcinoma 26235181 Both the single nucleotide polymorphism variants showed a positive association toward risk of lung cancer. genetics_GWAS hsa-mir-219 Schizophrenia 26257337 "These findings suggest that GRIN2B may be associated with schizophrenia and interaction effects of the polymorphisms in hsa-miR-219, CAKM2G, GRIN2B and GRIN3A may confer susceptibility to schizophrenia in the Chinese Han population." genetics_GWAS hsa-mir-100 "Squamous Cell Carcinoma, Esophageal" 26261633 Genetic variation in miR-100 rs1834306 is associated with decreased risk for esophageal squamous cell carcinoma in Kazakh patients in northwest China. genetics_GWAS hsa-let-7c Essential Hypertension 26274321 "In conclusion, our experimental results provide evidence that the T allele of rs17168525 in the 3'-UTR of myotrophin might influence the level of myotrophin protein by interfering with let-7/miR-98 binding." genetics_GWAS hsa-mir-503 Essential Hypertension 26274321 "In conclusion, our experimental results provide evidence that the T allele of rs17168525 in the 3'-UTR of myotrophin might influence the level of myotrophin protein by interfering with let-7/miR-98 binding." genetics_GWAS hsa-mir-98 Essential Hypertension 26274321 "In conclusion, our experimental results provide evidence that the T allele of rs17168525 in the 3'-UTR of myotrophin might influence the level of myotrophin protein by interfering with let-7/miR-98 binding." genetics_GWAS hsa-mir-146a Head And Neck Neoplasms 26277865 Significant association between functional microRNA polymorphisms and head and neck cancer susceptibility: a comprehensive meta-analysis. genetics_GWAS hsa-mir-149 Head And Neck Neoplasms 26277865 Significant association between functional microRNA polymorphisms and head and neck cancer susceptibility: a comprehensive meta-analysis. genetics_GWAS hsa-mir-196a-2 Head And Neck Neoplasms 26277865 Significant association between functional microRNA polymorphisms and head and neck cancer susceptibility: a comprehensive meta-analysis. genetics_GWAS hsa-mir-499 Head And Neck Neoplasms 26277865 Significant association between functional microRNA polymorphisms and head and neck cancer susceptibility: a comprehensive meta-analysis. genetics_GWAS hsa-mir-27a Colorectal Carcinoma 26302683 Genotype GG of rs895819 Functional Polymorphism Within miR-27a Might Increase Genetic Susceptibility to Colorectal Cancer in Han Chinese Population genetics_GWAS hsa-mir-34b Digestive System Neoplasms 26320502 The current evidence supports the conclusion that the miR-34b/c rs4938723 polymorphism decreases an individual's susceptibility to digestive cancers. genetics_GWAS hsa-mir-146a "Carcinoma, Renal Cell" 26323945 the observed association between the GG and GC genotype and poorer survival rate of RCC was at least partially mediated by the decreased expression of miR-146a. genetics_GWAS hsa-mir-214 Diabetes Mellitus 26329304 "We have detected the interactions of hsa-miR-214-5p/hsa-miR-550a-5p and the 3'UTR SNP of the HNF1B gene by in vitro luciferase reporter assays, and propose that the binding of such miRNAs regulates the expression of the HNF1B gene and the susceptibility of T2DM." genetics_GWAS hsa-mir-550a Diabetes Mellitus 26329304 "We have detected the interactions of hsa-miR-214-5p/hsa-miR-550a-5p and the 3'UTR SNP of the HNF1B gene by in vitro luciferase reporter assays, and propose that the binding of such miRNAs regulates the expression of the HNF1B gene and the susceptibility of T2DM." genetics_GWAS hsa-mir-146a Neoplasms [unspecific] 26337564 We conclude that rs2910164 may represent a valuable biomarker associated with the risk of developing specific types of cancer. genetics_GWAS hsa-mir-146a Gastric Neoplasms 26345764 "Overall, this meta-analysis failed to detect an association between five common miR-146a gene polymorphisms and GC susceptibility. However, this does not necessarily completely rule out a correlation between miRNA polymorphisms and GC susceptibility." genetics_GWAS hsa-mir-149 Gastric Neoplasms 26345764 "Overall, this meta-analysis failed to detect an association between five common miR-146a gene polymorphisms and GC susceptibility. However, this does not necessarily completely rule out a correlation between miRNA polymorphisms and GC susceptibility." genetics_GWAS hsa-mir-196a-2 Gastric Neoplasms 26345764 "Overall, this meta-analysis failed to detect an association between five common miR-146a gene polymorphisms and GC susceptibility. However, this does not necessarily completely rule out a correlation between miRNA polymorphisms and GC susceptibility." genetics_GWAS hsa-mir-27a Gastric Neoplasms 26345764 "Overall, this meta-analysis failed to detect an association between five common miR-146a gene polymorphisms and GC susceptibility. However, this does not necessarily completely rule out a correlation between miRNA polymorphisms and GC susceptibility." genetics_GWAS hsa-mir-499 Gastric Neoplasms 26345764 "Overall, this meta-analysis failed to detect an association between five common miR-146a gene polymorphisms and GC susceptibility. However, this does not necessarily completely rule out a correlation between miRNA polymorphisms and GC susceptibility." genetics_GWAS hsa-mir-146a Gastric Neoplasms 26345790 "In summary, the results suggested that the miR-146a rs2910164 polymorphism was related to gastric cancer risk in Asians but not in Caucasians, and no distinct correlation seemed to exist between the miR-196a-2 rs11614913 polymorphism and the risk of gastric cancer." genetics_GWAS hsa-mir-196a-2 Gastric Neoplasms 26345790 "In summary, the results suggested that the miR-146a rs2910164 polymorphism was related to gastric cancer risk in Asians but not in Caucasians, and no distinct correlation seemed to exist between the miR-196a-2 rs11614913 polymorphism and the risk of gastric cancer." genetics_GWAS hsa-mir-196a-2 "Carcinoma, Hepatocellular" 26365437 "In conclusion,the donor miR-196a-2 rs11614913 polymorphism is associated with HCC recurrence after LT and improves the predictive value of clinical models. The overexpression of miR-196a in the liver might provide a tumor-favorable environment for the development of HCC." genetics_GWAS hsa-mir-219-1 "Squamous Cell Carcinoma, Esophageal" 26379361 These findings indicated that functional polymorphisms miR-219-1 rs107822G > A might change individual susceptibility to Kazakh ESCC. genetics_GWAS hsa-mir-505 Gastric Neoplasms 26394032 "The PSMD10 rs111638916 SNP is highly associated with an increased risk of GC in Chinese patients, and could serve as a novel biomarker for this disease." genetics_GWAS hsa-mir-34b "Carcinoma, Thyroid, Papillary" 26402809 These findings indicate that the miR-34b/c rs4938723 and TP-53 Arg72Pro polymorphisms may contribute to the susceptibility of PTC. genetics_GWAS hsa-mir-34c "Carcinoma, Thyroid, Papillary" 26402809 These findings indicate that the miR-34b/c rs4938723 and TP-53 Arg72Pro polymorphisms may contribute to the susceptibility of PTC. genetics_GWAS hsa-mir-196a-2 Gastric Neoplasms 26406571 "Our studies suggested that the miR-146a rs2910164 polymorphism might marginally contribute to a decreased risk of gastric cancer, especially in Caucasians, whereas the miR-196a2 rs11614913 polymorphism might not be associated with susceptibility to GC." genetics_GWAS hsa-mir-155 Epilepsy 26425555 "This study first demonstrates the association of MIR155HG/miR-155 tag SNPs with epilepsy and shows that rare CNVs were found exclusively in epileptic patients, clarifying the genetic role of miR-155 in epilepsy." genetics_GWAS hsa-mir-146a Kidney Diseases [unspecific] 26426696 "There was no association of rs2910164 with susceptibility to IgAN in adults from a Chinese Han population. However, rs2910164 was correlated with the age of onset of IgAN in adult patients." genetics_GWAS hsa-mir-137 Schizophrenia 26429811 A GWAS SNP for Schizophrenia Is Linked to the Internal MIR137 Promoter and Supports Differential Allele-Specific Expression. genetics_GWAS hsa-mir-101-1 "Carcinoma, Hepatocellular" 26434859 "Our results revealed no significant association between miR-149 (rs2292832) and miR-101-1 (rs7536540) and the risk of HCC in our Thai population.However, this research is the first study of miR-149 (rs2292832) and miR-101-1 (rs7536541) in HCC in Thai populations and the results need to be confirmed with a larger population." genetics_GWAS hsa-mir-149 "Carcinoma, Hepatocellular" 26434859 "Our results revealed no significant association between miR-149 (rs2292832) and miR-101-1 (rs7536540) and the risk of HCC in our Thai population.However, this research is the first study of miR-149 (rs2292832) and miR-101-1 (rs7536540) in HCC in Thai populations and the results need to be confirmed with a larger population." genetics_GWAS hsa-mir-146a "Carcinoma, Cervical" 26464690 "The miR-146a (rs2910164) polymorphism is significantly correlated to ethnic factor and tumor diameters. miR-146a has differential expression in cervical tissues. Allele G of miR-146a (rs2910164) is related to the high expression of miR-146a, and the progression of cervical cancer." genetics_GWAS hsa-mir-196a-2 "Carcinoma, Hepatocellular" 26464719 "In conclusion, miR-196a2 rs11614913 polymorphism may contribute to identifying individuals, especially in HBV-infected subjects, who are at high risk for HCC." genetics_GWAS hsa-mir-92a Breast Neoplasms 26471763 "MDM4 SNP34091 status to be associated with reduced risk of breast cancer, in particular in individuals carrying the MDM2 SNP309GG genotype, but not to be associated with either lung-, colon- or prostate cancer." genetics_GWAS hsa-mir-146a Breast Neoplasms 26476291 The microRNA miR146a has a potential role in the development of breast cancer and the effects of its SNPs require further inquiry to determine the nature of their influence on breast tissue and cancer. genetics_GWAS hsa-mir-34b Male Infertility 26505368 Our results indicated that the MTHFR 3'-UTR rs55763075 polymorphism might modify the susceptibility to male infertility with idiopathic azoospermia. genetics_GWAS hsa-mir-146a Carotid Atherosclerosis 26505665 "The miR-146a rs2910164 polymorphism might be associated with carotid vulnerable plaque risk in Chinese type 2 diabetes mellitus patients, particularly in older patients, females, those with diabetes duration of more than 10 years and those with hypertension. The transcriptional coactivator p300 rs20551 polymorphism may not be a risk factor for the development or progression of atherosclerosis in type 2 diabetes mellitus." genetics_GWAS hsa-mir-423 "Squamous Cell Carcinoma, Esophageal" 26518769 "Four SNPs including miR-196a2 rs11614913, miR-146a rs2910164, miR-499 rs3746444, and miR-423 rs6505162 were selected with comprehensive collection strategy and genotyped using the SNaPshot Multiplex System." genetics_GWAS hsa-let-7 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-146 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-150 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-155 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-15a Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-16-1 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-21 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-221 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-222 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-29 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-34 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-372 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-373 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-708 Hematologic Neoplasms 26520014 our compiled results will be valuable for researchers interested in determining the role of target-SNPs in the development of hematological malignancies. genetics_GWAS hsa-mir-196a-2 Liver Cirrhosis 26529280 "In summary, rs12304647 is associated with a reduced risk of progression to HCC in patients with chronic HBV infection." genetics_GWAS hsa-mir-146a Acute Coronary Syndrome 26537765 These findings indicate that miR-146a rs2910164 may act as a novel molecular marker for ACS susceptibility. genetics_GWAS hsa-mir-196a-2 Atrial Fibrillation 26554236 "Our data support that the pre-miR-196a2 polymorphism is associated with AF, and the C allele is a risk factor for AF." genetics_GWAS hsa-mir-125 Diabetic Nephropathy 26563755 "We identified miR-125a as a direct regulator of IL-6R, and the genotype of rs12976445 might be a novel predictor of the development of DN in DM." genetics_GWAS hsa-mir-145 Breast Neoplasms 26577090 Our study is the first to report an association between a miR-SNP in MIR145 and breast cancer risk in individuals of Caucasian background. This finding requires further validation through genotyping of larger cohorts or in individuals of different ethnicities to determine the potential significance of this finding as well as studies aimed to determine functional significance. genetics_GWAS hsa-mir-499 Gastric Neoplasms 26597478 The present study indicated that miR-499 rs3746444 might contribute to GC risk and this SNP could be developed as a biomarker for GC prediction. genetics_GWAS hsa-mir-146a "Stroke, Ischemic" 26608782 "Although the 3 SNPs might be associated with IS, the association varied significantly in different countries." genetics_GWAS hsa-mir-196a-2 "Stroke, Ischemic" 26608782 "Although the 3 SNPs might be associated with IS, the association varied significantly in different countries." genetics_GWAS hsa-mir-499 "Stroke, Ischemic" 26608782 "Although the 3 SNPs might be associated with IS, the association varied significantly in different countries." genetics_GWAS hsa-mir-149 "Squamous Cell Carcinoma, Oral" 26625766 Our study suggests that miR-196a2C>T and miR-149C>T polymorphisms may play crucial roles in the development of OSCC in South Indian subjects. genetics_GWAS hsa-mir-124 Neoplasms [unspecific] 26625819 This meta-analysis suggests that the miR-124 rs531564 C > G polymorphism is an important risk factor for cancers among the Chinese population. genetics_GWAS hsa-let-7a "Carcinoma, Colon" 26630397 "Of the 327 SNPs identified in the literature as being important because of their potential regulation of miRNA expression levels, 12.5% had statistically significantly associations with miRNA expression. However, only two of these SNPs were significantly associated with colon cancer." genetics_GWAS hsa-mir-143 "Carcinoma, Colon" 26630397 "Of the 327 SNPs identified in the literature as being important because of their potential regulation of miRNA expression levels, 12.5% had statistically significantly associations with miRNA expression. However, only two of these SNPs were significantly associated with colon cancer." genetics_GWAS hsa-mir-145 "Carcinoma, Colon" 26630397 "Of the 327 SNPs identified in the literature as being important because of their potential regulation of miRNA expression levels, 12.5% had statistically significantly associations with miRNA expression. However, only two of these SNPs were significantly associated with colon cancer." genetics_GWAS hsa-mir-146a "Carcinoma, Colon" 26630397 "Of the 327 SNPs identified in the literature as being important because of their potential regulation of miRNA expression levels, 12.5% had statistically significantly associations with miRNA expression. However, only two of these SNPs were significantly associated with colon cancer." genetics_GWAS hsa-mir-19a "Carcinoma, Colon" 26630397 "Of the 327 SNPs identified in the literature as being important because of their potential regulation of miRNA expression levels, 12.5% had statistically significantly associations with miRNA expression. However, only two of these SNPs were significantly associated with colon cancer." genetics_GWAS hsa-mir-19b "Carcinoma, Colon" 26630397 "Of the 327 SNPs identified in the literature as being important because of their potential regulation of miRNA expression levels, 12.5% had statistically significantly associations with miRNA expression. However, only two of these SNPs were significantly associated with colon cancer." genetics_GWAS hsa-mir-214 "Carcinoma, Colon" 26630397 "Of the 327 SNPs identified in the literature as being important because of their potential regulation of miRNA expression levels, 12.5% had statistically significantly associations with miRNA expression. However, only two of these SNPs were significantly associated with colon cancer." genetics_GWAS hsa-mir-25 "Carcinoma, Colon" 26630397 "Of the 327 SNPs identified in the literature as being important because of their potential regulation of miRNA expression levels, 12.5% had statistically significantly associations with miRNA expression. However, only two of these SNPs were significantly associated with colon cancer." genetics_GWAS hsa-mir-525 "Carcinoma, Colon" 26630397 "Of the 327 SNPs identified in the literature as being important because of their potential regulation of miRNA expression levels, 12.5% had statistically significantly associations with miRNA expression. However, only two of these SNPs were significantly associated with colon cancer." genetics_GWAS hsa-mir-140 Bladder Neoplasms 26695686 "Together, these results suggest that rs35592567 in TP63 may be a novel causal variant contributing to the susceptibility to bladder cancer, which provides additional insight into the pathogenesis of bladder carcinogenesis." genetics_GWAS hsa-mir-196a-2 Breast Neoplasms 26710106 Somatic Mutation of the SNP rs11614913 and Its Association with Increased MIR 196A2 Expression in Breast Cancer. genetics_GWAS hsa-mir-603 Breast Neoplasms 26718432 "In conclusion,the findings indicated that Mir603 rs11014002 T allele might contribute to decrease the risk of BC in a sample of Iranian population. Further studies with larger sample sizes and different ethnicities are warranted to confirm our findings." genetics_GWAS hsa-mir-449a Gastric Neoplasms 26722545 "In conclusion, our findings suggest that miR-449a rs112310158 is a genetic risk factor for GC." genetics_GWAS hsa-mir-146a "Carcinoma, Thyroid, Papillary" 26722556 "Our study indicated that the miR-146a polymorphism was significantly associated with PTC risk. In contrast, meta-analysis revealed no evidence of association between miR-146a variants and PTC risk. Further studies are required to elucidate the role of miR-146a in the etiology of PTC." genetics_GWAS hsa-mir-492 "Carcinoma, Hepatocellular" 26753964 miR-492G>C polymorphism (rs2289030) is associated with overall survival of hepatocellular carcinoma patients. genetics_GWAS hsa-mir-146a Breast Neoplasms 26785832 "e identified one rare variant in MIR146A, four in MIR146B, five in BRCA1 3'-UTR and one in BRCA2 3'-UTR in 716 index cases and 619 controls." genetics_GWAS hsa-mir-146a Ovarian Neoplasms 26785832 "e identified one rare variant in MIR146A, four in MIR146B, five in BRCA1 3'-UTR and one in BRCA2 3'-UTR in 716 index cases and 619 controls." genetics_GWAS hsa-mir-146b Breast Neoplasms 26785832 "we identified one rare variant in MIR146A, four in MIR146B, five in BRCA1 3'-UTR and one in BRCA2 3'-UTR in 716 index cases and 619 controls." genetics_GWAS hsa-mir-146b Ovarian Neoplasms 26785832 "we identified one rare variant in MIR146A, four in MIR146B, five in BRCA1 3'-UTR and one in BRCA2 3'-UTR in 716 index cases and 619 controls." genetics_GWAS hsa-mir-146a Colorectal Carcinoma 26813595 "SNPs in the miRNA genes are important for tumorigenesis. The changes by hsa-mir-146a rs1052918 C>G may result in loss of Wnt, constant activation of the Wnt signaling pathway, and uncontrolled cell proliferation and tumor progression." genetics_GWAS hsa-mir-608 "Carcinoma, Hepatocellular" 26815502 MiR-608 rs4919510 is associated with prognosis of hepatocellular carcinoma. genetics_GWAS hsa-mir-149 "Carcinoma, Hepatocellular" 26823863 "Predictive role of miR-146a rs2910164 (C>G), miR-149 rs2292832 (T>C), miR-196a2 rs11614913 (T>C) and miR-499 rs3746444 (T>C) in the development of hepatocellular carcinoma." genetics_GWAS hsa-mir-137 Schizophrenia 26836412 Polymorphisms in MIR137HG and microRNA-137-regulated genes influence gray matter structure in schizophrenia. genetics_GWAS hsa-mir-199a "Adenocarcinoma, Pancreatic Ductal" 26872370 our study demonstrates that host genetic variants could disturb the regulation of the miR-199a/HIF1A regulatory loop and alter PDAC risk and poor prognosis. genetics_GWAS hsa-mir-146a Atherosclerosis 26875519 Apolipoprotein E Epsilon 4 Enhances the Association between the rs2910164 Polymorphism of miR-146a and Risk of Atherosclerotic Cerebral Infarction. genetics_GWAS hsa-mir-146a Coronary Artery Disease 26909569 "Our data provide the first evidence for the association of miR-146a rs2910164 and TCF21 rs12190287 with CAD in an Iranian population, encouraging further research to elucidate the disease-related effects of miR-146a rs2910164." genetics_GWAS hsa-mir-146a Lung Neoplasms 26926727 "Rs11614913, rs12894467 and rs2910164 polymorphism were potentially associated with primary lung cancer in Fujian Han population." genetics_GWAS hsa-mir-196a-2 Lung Neoplasms 26926727 "Rs11614913, rs12894467 and rs2910164 polymorphism were potentially associated with primary lung cancer in Fujian Han population." genetics_GWAS hsa-mir-26a-1 Lung Neoplasms 26926727 "Rs11614913, rs12894467 and rs2910164 polymorphism were potentially associated with primary lung cancer in Fujian Han population." genetics_GWAS hsa-mir-27a Lung Neoplasms 26926727 "Rs11614913, rs12894467 and rs2910164 polymorphism were potentially associated with primary lung cancer in Fujian Han population." genetics_GWAS hsa-mir-300 Lung Neoplasms 26926727 "Rs11614913, rs12894467 and rs2910164 polymorphism were potentially associated with primary lung cancer in Fujian Han population." genetics_GWAS hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 26959643 mutations in the mir-15a/16-1 loci are responsible for decreased expression genetics_GWAS hsa-mir-423 Lung Neoplasms 26973201 These findings suggest that miR-146a rs2910164C>G and miR-423 rs6505162C>A polymorphisms may contribute to genetic susceptibility to lung cancer and lung adenocarcinoma in Chinese non-smoking females. genetics_GWAS hsa-mir-146a Diabetic Nephropathy 26997512 Rs2910164 is significantly associated with microvascular complications DN in patients with T1DM and DME in patients with T2DM. genetics_GWAS hsa-mir-146a Diabetic Retinopathy 26997512 Rs2910164 is significantly associated with microvascular complications DN in patients with T1DM and DME in patients with T2DM. genetics_GWAS hsa-mir-618 "Stroke, Ischemic" 27011381 Our findings suggest that miR-618 SNP rs2682818 may play an important role in the recurrence of ischemic stroke. genetics_GWAS hsa-mir-149 Squamous Cell Carcinoma 27050146 hsa-mir-149 rs2292832 and hsa-mir-499 rs3746444 polymorphisms play a significant role in the prognosis of SCCNOP genetics_GWAS hsa-mir-365 Neuropsychiatric Disorders [unspecific] 27074815 single nucleotide polymorphism (SNP) rs2235749 (in high linkage disequilibrium with rs910080) modifies striatal PDYN expression via impaired binding of miR-365 genetics_GWAS hsa-mir-137 Schizophrenia 27096222 A single nucleotide polymorphism rs1625579 in the miR-137 gene has recently been reported to confer risk of schizophrenia genetics_GWAS hsa-mir-146a Psoriasis 27098222 "The miR-146a SNPs rs2910164, rs57095329, rs2431697 are associated with susceptibility to certain autoimmune diseases." genetics_GWAS hsa-mir-149 "Carcinoma, Hepatocellular" 27141902 "A meta-analysis of microRNA-149, microRNA-499 gene polymorphism and susceptibility to hepatocellular carcinoma" genetics_GWAS hsa-mir-146a Graft-Versus-Host Disease 27156151 "expression levels of miR-146aC>G, miR-196a2T>C and putative gene-gene interaction between miR-146a, miR-196a2, miR-149 may be involved in RIF development in Korean women." genetics_GWAS hsa-mir-149 Graft-Versus-Host Disease 27156151 "expression levels of miR-146aC>G, miR-196a2T>C and putative gene-gene interaction between miR-146a, miR-196a2, miR-149 may be involved in RIF development in Korean women." genetics_GWAS hsa-mir-196a-2 Graft-Versus-Host Disease 27156151 "expression levels of miR-146aC>G, miR-196a2T>C and putative gene-gene interaction between miR-146a, miR-196a2, miR-149 may be involved in RIF development in Korean women." genetics_GWAS hsa-mir-499a Graft-Versus-Host Disease 27156151 "expression levels of miR-146aC>G, miR-196a2T>C and putative gene-gene interaction between miR-146a, miR-196a2, miR-149 may be involved in RIF development in Korean women." genetics_GWAS hsa-mir-124 Mesial Temporal Lobe Epilepsy 27188998 "In this study, the effect of the SNP of one neuronal miRNA, miR-124, on susceptibility to MTLE was investigated using a case control study." genetics_GWAS hsa-mir-34b Osteoporosis 27227383 The present findings indicate that pri-miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms may contribute to the risk of OP. genetics_GWAS hsa-mir-34c Osteoporosis 27227383 The present findings indicate that pri-miR-34b/c rs4938723 and TP53 Arg72Pro polymorphisms may contribute to the risk of OP. genetics_GWAS hsa-let-7 Colorectal Carcinoma 27234654 rs868 is associated with lower TGFBR1 expression thereby increasing CRC risk. genetics_GWAS hsa-mir-130a "Stroke, Ischemic" 27246008 "Association of miR-34a, miR-130a, miR-150 and miR-155 polymorphisms with the risk of ischemic stroke" genetics_GWAS hsa-mir-150 "Stroke, Ischemic" 27246008 "Association of miR-34a, miR-130a, miR-150 and miR-155 polymorphisms with the risk of ischemic stroke" genetics_GWAS hsa-mir-155 "Stroke, Ischemic" 27246008 "Association of miR-34a, miR-130a, miR-150 and miR-155 polymorphisms with the risk of ischemic stroke" genetics_GWAS hsa-mir-34a "Stroke, Ischemic" 27246008 "Association of miR-34a, miR-130a, miR-150 and miR-155 polymorphisms with the risk of ischemic stroke" genetics_GWAS hsa-mir-146a Gastric Neoplasms 27267319 rs2910164 of miR-146a is associated with GC genetics_GWAS hsa-mir-27a "Diabetes Mellitus, Type 2" 27300034 The pre-mir-27a variant rs895819 may contribute to type 2 diabetes mellitus susceptibility genetics_GWAS hsa-mir-501 "Carcinoma, Hepatocellular" 27310251 We identified a novel SNP located in miR-501 acting as an important factor of the HCC susceptibility genetics_GWAS hsa-mir-214 "Squamous Cell Carcinoma, Esophageal" 27323028 esophageal squamous cell carcinoma genetics_GWAS hsa-mir-146a Rheumatoid Arthritis 27342690 12 single nucleotide polymorphisms genetics_GWAS hsa-mir-502 "Carcinoma, Renal Cell, Clear-Cell" 27346408 Polymorphism at the miR-502 binding site in the 3' untranslated region of SET8 gene is associated with the risk of clear cell renal cell carcinoma genetics_GWAS hsa-mir-149 "Carcinoma, Hepatocellular" 27348444 MIR-149 gene rs2292832 polymorphism contributed to the risk of HCC genetics_GWAS hsa-mir-370 Colorectal Carcinoma 27354594 "rs2279398G>A may affect the expression of DOK3 by altering the miRNA binding efficiency at the miRNA-binding sites of the 3'-UTR in DOK3, thereby impacting CRC tumorigenesis." genetics_GWAS hsa-mir-1273d Tooth Agenesis 27362534 our findings indicate that rs15705 and rs317250 are associated with the susceptibility of non-syndromic tooth agenesis by possibly affecting miRNAs and mRNA interaction. genetics_GWAS hsa-mir-4639 Tooth Agenesis 27362534 rs15705 and rs317250 are associated with the susceptibility of non-syndromic tooth agenesis by possibly affecting miRNAs and mRNA interaction. genetics_GWAS hsa-mir-429 "Carcinoma, Lung, Non-Small-Cell" 27374108 rs9660710 in miR-200b/200a/429 cluster and rs763354 in miR-30a might modify the susceptibility to NSCLC. genetics_GWAS hsa-mir-146a Hypertension 27379568 "This study suggests that the variant of miR-146aC>G polymorphism and allelic combinations, at least in Koreans, affect susceptibility to hypertension." genetics_GWAS hsa-mir-6826 Breast Neoplasms 27380242 "We systematically put together a list of 822 and 10,468 genetic variants among primary miRNA sequences and 38 genes in the miRNA biogenesis pathway" genetics_GWAS hsa-mir-608 Rectal Neoplasms 27381831 Sequence variation in mature microRNA-608 and benefit from neo-adjuvant treatment in locally advanced rectal cancer patients. genetics_GWAS hsa-mir-152 Asthma 27383317 Single nucleotide polymorphisms in the promoter region of mir-133a-1 and in pre-mir-152 rs1707 may contribute to the risk of asthma in a Chinese Han population. genetics_GWAS hsa-mir-142 "Lymphoma, Follicular" 27389057 "We found recurrent mutations of miR-142, which has not been previously been reported to be mutated in FL/tFL." genetics_GWAS hsa-mir-142 "Lymphoma, Large B-Cell, Diffuse" 27390358 "Additionally, we detected recurrent mutations of hsa-miR-142 in diffuse large B-cell lymphomas and follicular lymphomas, and editing of the hsa-miR-376 cluster, providing evidence for microRNA editing in lymphomagenesis." genetics_GWAS hsa-mir-376 "Lymphoma, Large B-Cell, Diffuse" 27390358 "we detected recurrent mutations of hsa-miR-142 in diffuse large B-cell lymphomas and follicular lymphomas, and editing of the hsa-miR-376 cluster, providing evidence for microRNA editing in lymphomagenesis." genetics_GWAS hsa-mir-483 "Squamous Cell Carcinoma, Esophageal" 27420938 SNP at miR-483-5p-binding site in the 3'-untranslated region of the BSG gene is associated with susceptibility to esophageal cancer in a Chinese population. genetics_GWAS hsa-mir-584 Pemphigus 27424220 "Collectively, these results suggest that a disease-associated SNP located within the 3'UTR of KLRG1 directly interferes with miR-584-5p binding, allowing for KLRG1 mRNA differential accumulation, which in turn may contribute to pathogenesis of autoimmune diseases, such as pemphigus." genetics_GWAS hsa-mir-206 Schizophrenia 27424800 Our study therefore suggests that miR-206 may contribute to schizophrenia risk through allele-dependent regulation of the genome-wide significant gene NT5C2. genetics_GWAS hsa-let-7a Osteosarcoma 27430246 "Taken together, the findings of the present study demonstrated that the KRAS 3'-UTR rs61764370 polymorphism interfered with miRNA/mRNA interaction, and showed that the minor allele was associated with an elevated risk of developing metastatic disease in OS." genetics_GWAS hsa-mir-146a Coronary Artery Disease 27430349 "miRNA polymorphisms (miRâ€?46a, miRâ€?49, miRâ€?96a2 and miRâ€?99) are associated with the risk of coronary artery disease." genetics_GWAS hsa-mir-149 Coronary Artery Disease 27430349 "miRNA polymorphisms (miRâ€?46a, miRâ€?49, miRâ€?96a2 and miRâ€?99) are associated with the risk of coronary artery disease." genetics_GWAS hsa-mir-196a-2 Coronary Artery Disease 27430349 "miRNA polymorphisms (miRâ€?46a, miRâ€?49, miRâ€?96a2 and miRâ€?99) are associated with the risk of coronary artery disease." genetics_GWAS hsa-mir-499 Coronary Artery Disease 27430349 "miRNA polymorphisms (miRâ€?46a, miRâ€?49, miRâ€?96a2 and miRâ€?99) are associated with the risk of coronary artery disease." genetics_GWAS hsa-mir-146a Asthma 27431205 "The miRâ€?46a rs2910164 polymorphism CC genotype was identified to be significantly associated with a decreased risk of BHR in response to intubation when compared with the GG or GC genotype (odds ratio, 0.38; confidence interval, 0.18â€?.78)." genetics_GWAS hsa-mir-125b Cataract 27431420 rs78378222 polymorphism in the 3'-untranslated region of TP53 contributes to development of age-associated cataracts by modifying microRNA-125b-induced apoptosis of lens epithelial cells. genetics_GWAS hsa-mir-146a Breast Neoplasms 27434289 "Logistic regression data represented the C allele of rs2910164 (OR = 4.00, p= 0.0037) as the risk allele and associated with Her2-positive phenotype." genetics_GWAS hsa-mir-143 Bladder Neoplasms 27438131 These findings suggest that the functional rs353293 polymorphism may be a useful biomarker to predict the risk of bladder cancer. genetics_GWAS hsa-mir-145 Bladder Neoplasms 27438131 These findings suggest that the functional rs353293 polymorphism may be a useful biomarker to predict the risk of bladder cancer. genetics_GWAS hsa-mir-145 Colorectal Carcinoma 27444415 These findings indicate that the rs353292 polymorphism is functional and may be a risk factor for the development of CRC. genetics_GWAS hsa-mir-499 "Carcinoma, Hepatocellular" 27453271 miR-499 rs3746444 was significantly associated with an increased the risk of HCC. genetics_GWAS hsa-mir-146a Ossification of Posterior Longitudinal Ligament 27454313 The miR-146a/-149/-196a2/-499 allele combinations may be a genetic risk factor for cervical OPLL in the Korean population. genetics_GWAS hsa-mir-149 Ossification of Posterior Longitudinal Ligament 27454313 The miR-146a/-149/-196a2/-499 allele combinations may be a genetic risk factor for cervical OPLL in the Korean population. genetics_GWAS hsa-mir-196a-2 Ossification of Posterior Longitudinal Ligament 27454313 The miR-146a/-149/-196a2/-499 allele combinations may be a genetic risk factor for cervical OPLL in the Korean population. genetics_GWAS hsa-mir-499 Ossification of Posterior Longitudinal Ligament 27454313 The results indicate that GG genotype of miR-499 is associated with significantly higher risks of OPLL in the segmental OPLL group. genetics_GWAS hsa-mir-196a-2 Asthma 27487239 microRNA-196a2 rs11614913 polymorphism might be associated with asthma severity in our sample of the Egyptian population. genetics_GWAS hsa-mir-149 "Squamous Cell Carcinoma, Head and Neck" 27515039 "However, no significant association was detected between the other three SNPs (miR-149 rs2292832, miR-146a rs2910164, and miR-608 rs4919510) and HNSCC risk." genetics_GWAS hsa-mir-1269b "Carcinoma, Oral" 27525378 "Genetic variants in microRNA-146a (C>G) and microRNA-1269b (G>C) are associated with the decreased risk of oral premalignant lesions, oral cancer, and pharyngeal cancer." genetics_GWAS hsa-mir-146a "Carcinoma, Oral" 27525378 "Genetic variants in microRNA-146a (C>G) and microRNA-1269b (G>C) are associated with the decreased risk of oral premalignant lesions, oral cancer, and pharyngeal cancer." genetics_GWAS hsa-mir-137 Schizophrenia 27525637 "Genome-wide association studies (GWAS) have identified a region at chromosome 1p21.3, containing the microRNA MIR137, to be among the most significant associations for schizophrenia." genetics_GWAS hsa-let-7 "Stroke, Ischemic" 27530126 An rs13293512 polymorphism in the promoter of let-7 is associated with a reduced risk of ischemic stroke. genetics_GWAS hsa-mir-155 Neoplasms [unspecific] 27531892 Our findings suggested that miR-155 and its functional variant rs767649 might contribute to the increased risk and poor prognosis of HCC genetics_GWAS hsa-mir-182 Glaucoma 27537254 A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. genetics_GWAS hsa-mir-27a Obesity 27537871 MicroRNAs and Drinking: Association between the Pre-miR-27a rs895819 Polymorphism and Alcohol Consumption in a Mediterranean Population. genetics_GWAS hsa-mir-124a Osteosarcoma 27540978 Single nucleotide polymorphism of hsa-miR-124a affects risk and prognosis of osteosarcoma. genetics_GWAS hsa-mir-526b "Squamous Cell Carcinoma, Esophageal" 27583835 A genetic polymorphism at miR-526b binding-site in the lincRNA-NR_024015 exon confers risk of esophageal squamous cell carcinoma in a population of North China. genetics_GWAS hsa-mir-130b "Stroke, Ischemic" 27603512 "Association of the Single Nucleotide Polymorphisms in microRNAs 130b, 200b, and 495 with Ischemic Stroke Susceptibility and Post-Stroke Mortality." genetics_GWAS hsa-mir-200b "Stroke, Ischemic" 27603512 "Association of the Single Nucleotide Polymorphisms in microRNAs 130b, 200b, and 495 with Ischemic Stroke Susceptibility and Post-Stroke Mortality." genetics_GWAS hsa-mir-495 "Stroke, Ischemic" 27603512 "Association of the Single Nucleotide Polymorphisms in microRNAs 130b, 200b, and 495 with Ischemic Stroke Susceptibility and Post-Stroke Mortality." genetics_GWAS hsa-mir-200b "Carcinoma, Breast" 27609814 "Mutation of putative miRNA-binding sites (miR-374a/b, miR-200b/c, miR-29a/b/c, miR-488) in these regions did not have significant impact on 3'UTR activity" genetics_GWAS hsa-mir-200c "Carcinoma, Breast" 27609814 "Mutation of putative miRNA-binding sites (miR-374a/b, miR-200b/c, miR-29a/b/c, miR-488) in these regions did not have significant impact on 3'UTR activity" genetics_GWAS hsa-mir-29a "Carcinoma, Breast" 27609814 "Mutation of putative miRNA-binding sites (miR-374a/b, miR-200b/c, miR-29a/b/c, miR-488) in these regions did not have significant impact on 4'UTR activity" genetics_GWAS hsa-mir-29b "Carcinoma, Breast" 27609814 "Mutation of putative miRNA-binding sites (miR-374a/b, miR-200b/c, miR-29a/b/c, miR-488) in these regions did not have significant impact on 5'UTR activity" genetics_GWAS hsa-mir-374a "Carcinoma, Breast" 27609814 "Mutation of putative miRNA-binding sites (miR-374a/b, miR-200b/c, miR-29a/b/c, miR-488) in these regions did not have significant impact on 6'UTR activity" genetics_GWAS hsa-mir-374b "Carcinoma, Breast" 27609814 "Mutation of putative miRNA-binding sites (miR-374a/b, miR-200b/c, miR-29a/b/c, miR-488) in these regions did not have significant impact on 7'UTR activity" genetics_GWAS hsa-mir-488 "Carcinoma, Breast" 27609814 "Mutation of putative miRNA-binding sites (miR-374a/b, miR-200b/c, miR-29a/b/c, miR-488) in these regions did not have significant impact on 8'UTR activity" genetics_GWAS hsa-mir-214 "Carcinoma, Hepatocellular" 27619679 U/G SNP rs111904020 in 3'UTR of STAT3 regulated by miR-214 promotes hepatocellular carcinoma development in Chinese population. genetics_GWAS hsa-mir-149 Lung Neoplasms 27685326 MicroRNA-149 rs2292832 polymorphism may not be associated with lung cancer risk in Chinese non-smoking female genetics_GWAS hsa-mir-146a "Carcinoma, Ovarian" 27706635 miR-146a and miR-196a2 polymorphisms in ovarian cancer risk. genetics_GWAS hsa-mir-196a-2 "Carcinoma, Ovarian" 27706635 miR-146a and miR-196a2 polymorphisms in ovarian cancer risk. genetics_GWAS hsa-mir-146a "Carcinoma, Colon" 27706637 MicroRNA variants and colorectal cancer risk: a meta-analysis. genetics_GWAS hsa-mir-149 "Carcinoma, Colon" 27706637 MicroRNA variants and colorectal cancer risk: a meta-analysis. genetics_GWAS hsa-mir-196a "Carcinoma, Colon" 27706637 MicroRNA variants and colorectal cancer risk: a meta-analysis. genetics_GWAS hsa-mir-27a "Carcinoma, Colon" 27706637 MicroRNA variants and colorectal cancer risk: a meta-analysis. genetics_GWAS hsa-mir-499 "Carcinoma, Colon" 27706637 MicroRNA variants and colorectal cancer risk: a meta-analysis. genetics_GWAS hsa-mir-146a "Carcinoma, Hepatocellular" 27706712 "Contributions of polymorphisms in miR146a, miR196a, and miR499 to the development of hepatocellular carcinoma." genetics_GWAS hsa-mir-196a "Carcinoma, Hepatocellular" 27706712 "Contributions of polymorphisms in miR146a, miR196a, and miR499 to the development of hepatocellular carcinoma." genetics_GWAS hsa-mir-499 "Carcinoma, Hepatocellular" 27706712 "Contributions of polymorphisms in miR146a, miR196a, and miR499 to the development of hepatocellular carcinoma." genetics_GWAS hsa-mir-27a "Carcinoma, Colon" 27751356 Association between microRNA-27a rs895819 polymorphism and risk of colorectal cancer: A meta-analysis. genetics_GWAS hsa-mir-196a-2 Glioma 27796868 Effect of rs11614913 Polymorphism on Mature miR196a2 Expression and its Target Gene HOXC8 Expression in Human Glioma. genetics_GWAS hsa-mir-34a Neuroblastoma 27805929 Genetic variant rs3750625 in the 3'UTR of ADRA2A affects stress-dependent acute pain severity after trauma and alters a microRNA-34a regulatory site. genetics_GWAS hsa-mir-627 "Carcinoma, Breast" 27807724 rs15869 at miRNA binding site in BRCA2 is associated with breast cancer susceptibility. genetics_GWAS hsa-mir-34b "Carcinoma, Hepatocellular" 27808368 Association between polymorphisms in the promoter region of pri-miR-34b/c and risk of hepatocellular carcinoma. genetics_GWAS hsa-mir-34c "Carcinoma, Hepatocellular" 27808368 Association between polymorphisms in the promoter region of pri-miR-34b/c and risk of hepatocellular carcinoma. genetics_GWAS hsa-mir-196a-2 Congenital Heart Diseases 27813602 "Association of miR-196a2, miR-27a, and miR-499 polymorphisms with isolated congenital heart disease in a Chinese population." genetics_GWAS hsa-mir-27a Congenital Heart Diseases 27813602 "Association of miR-196a2, miR-27a, and miR-499 polymorphisms with isolated congenital heart disease in a Chinese population." genetics_GWAS hsa-mir-499 Congenital Heart Diseases 27813602 "Association of miR-196a2, miR-27a, and miR-499 polymorphisms with isolated congenital heart disease in a Chinese population." genetics_GWAS hsa-mir-125a "Carcinoma, Hepatocellular" 27814341 Association Between microRNA-125a rs12976445 C>T Polymorphism and 18F-Fluorodeoxyglucose (18FDG) Uptake: Clinical and Metabolic Response in Patients with Non-Small Cell Lung Cancer. genetics_GWAS hsa-mir-146a Kaposi Sarcoma 27819716 Association of genetic variations in miR-146a rs2910164 and miR-149 rs11614913 with the development of classic Kaposi sarcoma. genetics_GWAS hsa-mir-149 Kaposi Sarcoma 27819716 Association of genetic variations in miR-146a rs2910164 and miR-149 rs11614913 with the development of classic Kaposi sarcoma. genetics_GWAS hsa-mir-146a "Carcinoma, Colon" 27824903 miR-146a Polymorphism (rs2910164) Predicts Colorectal Cancer Patients' Susceptibility to Liver Metastasis. genetics_GWAS hsa-mir-205 "Carcinoma, Breast" 27885248 Rs3842530 Polymorphism in MicroRNA-205 Host Gene in Lung and Breast Cancer Patients. genetics_GWAS hsa-mir-146a "Carcinoma, Hepatocellular" 27886162 miR-146a rs2910164 and hepatocellular carcinoma: a meta-analysis. genetics_GWAS hsa-mir-34b "Leukemia, Lymphoblastic, Acute, Childhood" 27886674 Pri-miR-34b/c rs4938723 polymorphism is associated with the risk of childhood acute lymphoblastic leukemia. genetics_GWAS hsa-mir-34c "Leukemia, Lymphoblastic, Acute, Childhood" 27886674 Pri-miR-34b/c rs4938723 polymorphism is associated with the risk of childhood acute lymphoblastic leukemia. genetics_GWAS hsa-mir-27a Human Immunodeficiency Virus Infection 27919232 microRNA-27a rs895819 is associated with obesity in HIV infected preeclamptic Black South African women on HAART. genetics_GWAS hsa-mir-34b "Carcinoma, Prostate" 27983526 Pri-miR-34b/c rs4938723 polymorphism increased the risk of prostate cancer. genetics_GWAS hsa-mir-34c "Carcinoma, Prostate" 27983526 Pri-miR-34b/c rs4938723 polymorphism increased the risk of prostate cancer. genetics_GWAS hsa-let-7 Liver Cirrhosis 27992614 A Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Men. genetics_GWAS hsa-mir-3131 "Carcinoma, Hepatocellular" 28034876 An indel polymorphism within pre-miR3131 confers risk for hepatocellular carcinoma. genetics_GWAS hsa-mir-1269a "Carcinoma, Hepatocellular" 28081866 A single nucleotide variant in microRNA-1269a promotes the occurrence and process of hepatocellular carcinoma by targeting to oncogenes SPATS2L and LRP6. genetics_GWAS hsa-mir-122 Chronic Hepatitis C 28082397 Differential hepatitis C virus RNA target site selection and host factor activities of naturally occurring miR-122 3? variants. genetics_GWAS hsa-mir-146a Rheumatoid Arthritis 28083614 Significance of Polymorphism and Expression of miR-146a and NFkB1 Genetic Variants in Patients with Rheumatoid Arthritis. genetics_GWAS hsa-mir-146a "Diabetes Mellitus, Type 2" 28101643 Polymorphisms in genes encoding miR-155 and miR-146a are associated with protection to type 1 diabetes mellitus. genetics_GWAS hsa-mir-155 "Diabetes Mellitus, Type 2" 28101643 Polymorphisms in genes encoding miR-155 and miR-146a are associated with protection to type 1 diabetes mellitus. genetics_GWAS hsa-mir-34b Retinoblastoma 28106538 A polymorphism in mir-34b/c as a potential biomarker for early onset of hereditary retinoblastoma. genetics_GWAS hsa-mir-34c Retinoblastoma 28106538 A polymorphism in mir-34b/c as a potential biomarker for early onset of hereditary retinoblastoma. genetics_GWAS hsa-mir-1203 "Stroke, Ischemic" 28171870 Methylene Tetrahydrofolate Reductase (MTHFR) rs868014 Polymorphism Regulated by miR-1203 Associates with Risk and Short Term Outcome of Ischemic Stroke. genetics_GWAS hsa-mir-149 Allergic Rhinitis 28181414 A functional variant of miRNA-149 confers risk for allergic rhinitis and comorbid asthma in Chinese children. genetics_GWAS hsa-mir-146a "Carcinoma, Hepatocellular" 28188097 "Our findings supported the proposition that the polymorphisms of miR-146a rs2910164, miR-196a2 rs11614913, and miR-196a2 rs11614913 may contribute to the susceptibility of HCC" genetics_GWAS hsa-mir-196a "Carcinoma, Hepatocellular" 28188097 "Our findings supported the proposition that the polymorphisms of miR-146a rs2910164, miR-196a2 rs11614913, and miR-196a2 rs11614913 may contribute to the susceptibility of HCC" genetics_GWAS hsa-mir-27b "Carcinoma, Gastric" 28214904 rs10719 Polymorphism Located within DROSHA 3'-Untranslated Region is Responsible for Development of Primary Hypertension by Disrupting Binding with microRNA-27b. genetics_GWAS hsa-mir-199a "Stroke, Ischemic" 28234972 the +936C/T variants significantly increased the risk of poorer stroke outcome by affecting the bindings of miR-199a and miR-199b to VEGF mRNA at the rs30250340 polymorphic site genetics_GWAS hsa-mir-199b "Stroke, Ischemic" 28234972 the +936C/T variants significantly increased the risk of poorer stroke outcome by affecting the bindings of miR-199a and miR-199b to VEGF mRNA at the rs30250340 polymorphic site genetics_GWAS hsa-mir-126 Endometriosis 28277133 mir-126 rs4636297 and TGF¦ÂRI rs334348 functional gene variants are associated with susceptibility to endometriosis and its severity. genetics_GWAS hsa-mir-218 "Carcinoma, Gastric" 28298809 "Predictive Value of MiR-219-1, MiR-938, MiR-34b/c, and MiR-218 Polymorphisms for Gastric Cancer Susceptibility and Prognosis." genetics_GWAS hsa-mir-219 "Carcinoma, Gastric" 28298809 "Predictive Value of MiR-219-1, MiR-938, MiR-34b/c, and MiR-218 Polymorphisms for Gastric Cancer Susceptibility and Prognosis." genetics_GWAS hsa-mir-34b "Carcinoma, Gastric" 28298809 "Predictive Value of MiR-219-1, MiR-938, MiR-34b/c, and MiR-218 Polymorphisms for Gastric Cancer Susceptibility and Prognosis." genetics_GWAS hsa-mir-34c "Carcinoma, Gastric" 28298809 "Predictive Value of MiR-219-1, MiR-938, MiR-34b/c, and MiR-218 Polymorphisms for Gastric Cancer Susceptibility and Prognosis." genetics_GWAS hsa-mir-938 "Carcinoma, Gastric" 28298809 "Predictive Value of MiR-219-1, MiR-938, MiR-34b/c, and MiR-218 Polymorphisms for Gastric Cancer Susceptibility and Prognosis." genetics_GWAS hsa-mir-196a "Colitis, Ulcerative" 28301487 Association of miR-196a-2 and miR-499 variants with ulcerative colitis and their correlation with expression of respective miRNAs. genetics_GWAS hsa-mir-499 "Colitis, Ulcerative" 28301487 Association of miR-196a-2 and miR-499 variants with ulcerative colitis and their correlation with expression of respective miRNAs. genetics_GWAS hsa-let-7 Macular Degeneration 28343170 "miRNAs, single nucleotide polymorphisms (SNPs) and age-related macular degeneration (AMD)." genetics_GWAS hsa-let-7a Macular Degeneration 28343170 "miRNAs, single nucleotide polymorphisms (SNPs) and age-related macular degeneration (AMD)." genetics_GWAS hsa-let-7b Macular Degeneration 28343170 "miRNAs, single nucleotide polymorphisms (SNPs) and age-related macular degeneration (AMD)." genetics_GWAS hsa-let-7d Macular Degeneration 28343170 "miRNAs, single nucleotide polymorphisms (SNPs) and age-related macular degeneration (AMD)." genetics_GWAS hsa-mir-146a Macular Degeneration 28343170 "miRNAs, single nucleotide polymorphisms (SNPs) and age-related macular degeneration (AMD)." genetics_GWAS hsa-mir-155 Macular Degeneration 28343170 "miRNAs, single nucleotide polymorphisms (SNPs) and age-related macular degeneration (AMD)." genetics_GWAS hsa-mir-101 "Carcinoma, Hepatocellular" 28366737 miRNA-101-1 and miRNA-221 expressions and their polymorphisms as biomarkers for early diagnosis of hepatocellular carcinoma. genetics_GWAS hsa-mir-221 "Carcinoma, Hepatocellular" 28366737 miRNA-101-1 and miRNA-221 expressions and their polymorphisms as biomarkers for early diagnosis of hepatocellular carcinoma. genetics_GWAS hsa-mir-4293 "Carcinoma, Lung, Non-Small-Cell" 28410417 Genetic variant of miR-4293 rs12220909 is associated with susceptibility to non-small cell lung cancer in a Chinese Han population. genetics_GWAS hsa-mir-423 Neoplasms [unspecific] 28430524 miRNA-Related Polymorphisms in miR-423 (rs6505162) and PEX6 (rs1129186) and Risk of Esophageal Squamous Cell Carcinoma in an Iranian Cohort. genetics_GWAS hsa-mir-122 "Carcinoma, Hepatocellular" 28512857 Interest of variations in microRNA-152 and -122 in a series of hepatocellular carcinomas related to hepatitis C virus infection. genetics_GWAS hsa-mir-149 Gastric Neoplasms 28523307 miR-149 rs2292832 C>T polymorphism and risk of gastric cancer. genetics_GWAS hsa-mir-608 "Carcinoma, Colon" 28653886 The miR-608 rs4919510 polymorphism may modify cancer susceptibility based on type. genetics_GWAS hsa-mir-146a Melanoma 28654546 Sex-specific effect of RNASEL rs486907 and miR-146a rs2910164 polymorphisms' interaction as a susceptibility factor for melanoma skin cancer. genetics_GWAS hsa-mir-146a Atherosclerosis 28674224 Association of NFKB1A and microRNAs variations and the susceptibility to atherosclerosis. genetics_GWAS hsa-mir-181a Neuroinflammation 28769921 MicroRNA-181 Variants Regulate T Cell Phenotype in the Context of Autoimmune Neuroinflammation genetics_GWAS hsa-mir-181b Neuroinflammation 28769921 MicroRNA-181 Variants Regulate T Cell Phenotype in the Context of Autoimmune Neuroinflammation. genetics_GWAS hsa-mir-146a Thyroid Neoplasms 28899898 The rs2910164 variant in MIR146A is significantly associated with DTC genetics_GWAS hsa-mir-149 "Squamous Cell Carcinoma, Oral" 29103762 miRNA genetic variants: As potential diagnostic biomarkers for oral cancer. genetics_GWAS hsa-mir-146a Lung Neoplasms 29127520 MiR-146a rs2910164 polymorphism might be associated with the susceptibility to lung cancer and nasopharyngeal carcinoma genetics_GWAS hsa-mir-146a Nasopharyngeal Neoplasms 29127520 MiR-146a rs2910164 polymorphism might be associated with the susceptibility to lung cancer and nasopharyngeal carcinoma genetics_GWAS hsa-mir-122 Stroke 29145255 Functional polymorphism rs3783553 in the 3'-untranslated region of IL-1A increased the risk of ischemic stroke genetics_GWAS hsa-mir-196a Crohn Disease 29152405 "Association of miR-146 rs2910164, miR-196a rs11614913, miR-221 rs113054794 and miR-224 rs188519172 polymorphisms with anti-TNF treatment response in a Greek population with Crohn's disease" genetics_GWAS hsa-let-7i "Squamous Cell Carcinoma, Cerevial" 29154871 Association between genetic polymorphisms in the promoters of let-7 and risk of cervical squamous cell carcinoma genetics_GWAS hsa-mir-146a Creutzfeldt-Jakob Disease 29216791 The associations of two SNPs in miRNA-146a and one SNP in ZBTB38-RASA2 with the disease susceptibility and the clinical features of the Chinese patients of sCJD and FFI. genetics_GWAS hsa-mir-126 Myocardial Infarction 29304813 The association between pre-miR-27a rs895819 polymorphism and myocardial infarction risk in a Chinese Han population genetics_GWAS hsa-mir-98 Osteoporosis 29307778 Computational and functional characterization of four SNPs in the SOST locus associated with osteoporosis genetics_GWAS hsa-mir-423 Colorectal Carcinoma 29419695 Association of microRNA-423 rs6505162 C>A polymorphism with susceptibility and metastasis of colorectal carcinoma. genetics_GWAS hsa-mir-146a Bladder Neoplasms 29491365 "miR-146a rs2910164 polymorphism is a risk factor for urological neoplasms, particularly for bladder cancer" genetics_GWAS hsa-mir-6720 Lymphedema 29511529 "rs121909106 and rs121909107 were predicted to have the most harmful effects, while hsa-miR-6886-5p, hsa-miR-6886-5p and hsa-miR-6720-3p were predicted to be the most important miRNAs affected" genetics_GWAS hsa-mir-6886 Lymphedema 29511529 "rs121909106 and rs121909107 were predicted to have the most harmful effects, while hsa-miR-6886-5p, hsa-miR-6886-5p and hsa-miR-6720-3p were predicted to be the most important miRNAs affected" genetics_GWAS hsa-mir-146a Breast Neoplasms 29521182 "Effects of miR-27a, miR-196a2 and miR-146a polymorphisms on the risk of breast cancer" genetics_GWAS hsa-mir-196a-2 Breast Neoplasms 29521182 "Effects of miR-27a, miR-196a2 and miR-148a polymorphisms on the risk of breast cancer" genetics_GWAS hsa-mir-27a Breast Neoplasms 29521182 "Effects of miR-27a, miR-196a2 and miR-147a polymorphisms on the risk of breast cancer" genetics_GWAS hsa-mir-556 "Carcinoma, Renal Cell, Clear-Cell" 29569387 A novel functional polymorphism of GSTM3 reduces clear cell renal cell carcinoma risk through enhancing its expression by interfering miR-556 binding. genetics_GWAS hsa-mir-146a Psoriasis 29587639 "A single nucleotide polymorphism in the miR-146a gene (rs2910164), aberrantly alters its gene expression and linked with the pathogenesis of several disorders, including psoriasis and PsA" genetics_GWAS hsa-mir-146a Psoriatic Arthritis 29587639 "A single nucleotide polymorphism in the miR-146a gene (rs2910164), aberrantly alters its gene expression and linked with the pathogenesis of several disorders, including psoriasis and PsA" genetics_GWAS hsa-mir-1302 Infertility 29627965 Association of T/A polymorphism in miR-1302 binding site in CGA gene with male infertility in Isfahan population. genetics_GWAS hsa-mir-146a Polycystic Ovarian Syndrome 29637801 "women with miR-146a variation are at a higher risk for developing PCOS, which can be due to up-regulation of miR-146a" genetics_GWAS hsa-mir-196a-2 "Squamous Cell Carcinoma, Head and Neck" 29705927 "Single nucleotide polymorphism rs11614913 associated with CC genotype in miR-196a2 is overrepresented in laryngeal squamous cell carcinoma, but not salivary gland tumors in Polish population." genetics_GWAS hsa-mir-146a Colorectal Carcinoma 29715515 Hsa-mir-149C/T rs2292832 and hsa-mir-146a G/C rs2910164 may influence CRC risk in an ethnicity-dependent manner by interfering with CRC progression parameters in Tunisian cohort genetics_GWAS hsa-mir-149 Colorectal Carcinoma 29715515 Hsa-mir-149C/T rs2292832 and hsa-mir-146a G/C rs2910164 may influence CRC risk in an ethnicity-dependent manner by interfering with CRC progression parameters in Tunisian cohort genetics_GWAS hsa-mir-149 Charcot-Marie-Tooth Disease Type 1A 29729827 Association of miR-149 polymorphism with onset age and severity in Charcot-Marie-Tooth disease type 1A. genetics_GWAS hsa-mir-218 Neuroblastoma 29858046 the miR-34b/c rs4938723?T > C and miR-218 rs11134527 A > G polymorphisms displayed a protective role from neuroblastoma genetics_GWAS hsa-mir-34b Neuroblastoma 29858046 the miR-34b/c rs4938723?T > C and miR-218 rs11134527 A > G polymorphisms displayed a protective role from neuroblastoma genetics_GWAS hsa-mir-34c Neuroblastoma 29858046 the miR-34b/c rs4938723?T > C and miR-218 rs11134527 A > G polymorphisms displayed a protective role from neuroblastoma genetics_GWAS hsa-mir-124-1 Gastric Neoplasms 29938592 Influence of single nucleotide polymorphisms in pri-miR-124-1 and STAT3 genes on gastric cancer susceptibility. genetics_GWAS hsa-mir-499 "Carcinoma, Hepatocellular" 29946268 "miR-499 rs3746444 is associated with susceptibility of cervical squamous cell carcinoma, lung cancer, prostate cancer, and hepatocellular carcinoma" genetics_GWAS hsa-mir-499 Lung Neoplasms 29946268 "miR-499 rs3746444 is associated with susceptibility of cervical squamous cell carcinoma, lung cancer, prostate cancer, and hepatocellular carcinoma" genetics_GWAS hsa-mir-499 Prostate Neoplasms 29946268 "miR-499 rs3746444 is associated with susceptibility of cervical squamous cell carcinoma, lung cancer, prostate cancer, and hepatocellular carcinoma" genetics_GWAS hsa-mir-499 "Squamous Cell Carcinoma, Cerevial" 29946268 "miR-499 rs3746444 is associated with susceptibility of cervical squamous cell carcinoma, lung cancer, prostate cancer, and hepatocellular carcinoma" genetics_GWAS hsa-mir-499 "Carcinoma, Hepatocellular" 29970712 MiR-499 rs3746444 polymorphism and hepatocellular carcinoma risk: A meta-analysis. genetics_GWAS hsa-mir-146a Prostate Neoplasms 30001553 "Polymorphisms of miR-196a2 rs11614913, miR-146a rs2910164, and miR-499 rs3746444 may contribute to the risk for developing prostate cancer in Asian descendants" genetics_GWAS hsa-mir-196a Prostate Neoplasms 30001553 "Polymorphisms of miR-196a2 rs11614913, miR-146a rs2910164, and miR-499 rs3746444 may contribute to the risk for developing prostate cancer in Asian descendants" genetics_GWAS hsa-mir-499 Prostate Neoplasms 30001553 "Polymorphisms of miR-196a2 rs11614913, miR-146a rs2910164, and miR-499 rs3746444 may contribute to the risk for developing prostate cancer in Asian descendants" genetics_GWAS hsa-mir-122 Hepatitis C Virus Infection 30053137 "miR-122, small RNA annealing and sequence mutations alter the predicted structure of the Hepatitis C virus 5' UTR RNA to stabilize and promote viral RNA accumulation." genetics_GWAS hsa-mir-146a Lung Neoplasms 30069329 "We found that an allele carriers of miR-146a rs2910164 (P=0.022, OR=1.315) and C allele carriers of miR-149 rs71428439 (P=0.042, OR=1.372) performance a high risk of lung cancer" genetics_GWAS hsa-mir-149 Lung Neoplasms 30069329 "We found that an allele carriers of miR-146a rs2910164 (P=0.022, OR=1.315) and C allele carriers of miR-149 rs71428439 (P=0.042, OR=1.372) performance a high risk of lung cancer" genetics_GWAS hsa-mir-499 Congenital Heart Diseases 30084801 Association of a MiR-499 SNP and risk of congenital heart disease in a Chinese population. genetics_GWAS hsa-mir-499 Cardiovascular Diseases [unspecific] 30102014 A polymorphism rs3746444 within the pre-miR-499 alters the maturation of miR-499-5p and its antiapoptotic function. genetics_GWAS hsa-mir-218 "Squamous Cell Carcinoma, Esophageal" 30120974 Association between miR-218 rs11134527 polymorphism and risk of selected types of cancer in Asian population: An updated meta-analysis of case-control studies. genetics_GWAS hsa-mir-125a "Carcinoma, Breast" 30135399 "Genetic Variants in pre-miR-146a, pre-miR-499, pre-miR-125a, pre-miR-605, and pri-miR-182 Are Associated with Breast Cancer Susceptibility in a South American Population." genetics_GWAS hsa-mir-146a "Carcinoma, Breast" 30135399 "Genetic Variants in pre-miR-146a, pre-miR-499, pre-miR-125a, pre-miR-605, and pri-miR-182 Are Associated with Breast Cancer Susceptibility in a South American Population." genetics_GWAS hsa-mir-182 "Carcinoma, Breast" 30135399 "Genetic Variants in pre-miR-146a, pre-miR-499, pre-miR-125a, pre-miR-605, and pri-miR-182 Are Associated with Breast Cancer Susceptibility in a South American Population." genetics_GWAS hsa-mir-499 "Carcinoma, Breast" 30135399 "Genetic Variants in pre-miR-146a, pre-miR-499, pre-miR-125a, pre-miR-605, and pri-miR-182 Are Associated with Breast Cancer Susceptibility in a South American Population." genetics_GWAS hsa-mir-605 "Carcinoma, Breast" 30135399 "Genetic Variants in pre-miR-146a, pre-miR-499, pre-miR-125a, pre-miR-605, and pri-miR-182 Are Associated with Breast Cancer Susceptibility in a South American Population." genetics_GWAS hsa-mir-3161 Glaucoma 30148417 "MicroRNA-related polymorphisms in pseudoexfoliation syndrome, pseudoexfoliative glaucoma, and primary open-angle glaucoma." genetics_GWAS hsa-mir-21 Atherosclerosis 30205366 rs145204276 was associated with the risk of atherosclerosis by affecting the proliferation and apoptosis of endothelial cells via regulating the GAS5/miR-21/PDCD4 signaling pathway genetics_GWAS hsa-mir-499 "Stroke, Ischemic" 30229913 hsa-mir-499 rs3746444 A/G polymorphism may be associated with a significantly increased risk of IS in an Iranian population genetics_GWAS hsa-mir-34a Gastric Neoplasms 30242897 Minor allele of rs1057317 polymorphism in TLR4 is associated with increased risk of Helicobacter pylori -induced gastric cancer. genetics_GWAS hsa-mir-146a "Stroke, Ischemic" 30254431 the GG genotype of miR-146a (rs2910164) and CC genotype of miR-149 (rs2292832) may confer increased susceptibility to IS genetics_GWAS hsa-mir-149 "Stroke, Ischemic" 30254431 the GG genotype of miR-146a (rs2910164) and CC genotype of miR-149 (rs2292832) may confer increased susceptibility to IS genetics_GWAS hsa-mir-300 Lung Neoplasms 30271206 miR-300 rs12894467 polymorphism may be associated with susceptibility to primary lung cancer in the Chinese Han population. genetics_GWAS hsa-mir-149 Gastric Neoplasms 30274913 Association Between miR-149 Gene rs2292832 Polymorphism and Risk of Gastric Cancer: A Case-control Study. genetics_GWAS hsa-mir-146a "Colitis, Ulcerative" 30278502 Association of miRNA-146a rs2910164 and miRNA-196 rs11614913 polymorphisms in patients with ulcerative colitis: A meta-analysis and review. genetics_GWAS hsa-mir-196a "Colitis, Ulcerative" 30278502 Association of miRNA-146a rs2910164 and miRNA-196 rs11614913 polymorphisms in patients with ulcerative colitis: A meta-analysis and review. genetics_GWAS hsa-mir-423 Coronary Artery Disease 30289085 Potential impact of microRNA-423 gene variability in coronary artery disease. genetics_GWAS hsa-mir-125a "Carcinoma, Lung" 30302847 Regulation of miR-125a expression by rs12976445 single-nucleotide polymorphism?is associated with radiotherapy-induced pneumonitis in lung carcinoma patients. genetics_GWAS hsa-mir-589 Cataract 30315181 luciferase reporter gene expression can be down regulated by hsa-miR-589-5p in cells transfected with rs2229090 C allele compared to G allele genetics_GWAS hsa-mir-579 Anxiety Disorders 30341278 A functional genetic variation of SLC6A2 repressor hsa-miR-579-3p upregulates sympathetic noradrenergic processes of fear and anxiety. genetics_GWAS hsa-mir-21 Inflammation 30375257 Cigarette smoking affects microRNAs and inflammatory biomarkers in healthy individuals and an association to single nucleotide polymorphisms is indicated. genetics_knock down_promote hsa-mir-15a Leukemia 12434020 deletion or downregulation genetics_knock down_promote hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 12434020 deletion or downregulation genetics_knock down_promote hsa-mir-16-1 Leukemia 12434020 deletion or downregulation genetics_knock down_promote hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 12434020 deletion or downregulation genetics_knock down_promote hsa-mir-125b-1 Breast Neoplasms 14973191 deletion genetics_knock down_promote hsa-mir-125b-1 Lung Neoplasms 14973191 deletion genetics_knock down_promote hsa-mir-125b-1 Ovarian Neoplasms 14973191 deletion genetics_knock down_promote hsa-mir-125b-1 Urinary Bladder Cancer 14973191 deletion genetics_knock down_promote hsa-mir-17 "Carcinoma, Hepatocellular" 15944709 loss of heterozygosity of this cluster genetics_knock down_promote hsa-mir-18a "Carcinoma, Hepatocellular" 15944709 loss of heterozygosity of this cluster genetics_knock down_promote hsa-mir-19a "Carcinoma, Hepatocellular" 15944709 loss of heterozygosity of this cluster genetics_knock down_promote hsa-mir-19b-1 "Carcinoma, Hepatocellular" 15944709 loss of heterozygosity of this cluster genetics_knock down_promote hsa-mir-20a "Carcinoma, Hepatocellular" 15944709 loss of heterozygosity of this cluster genetics_knock down_promote hsa-mir-125b-1 "Leukemia-Lymphoma, Precursor B-Cell Lymphoblastic" 16151463 an insertion of pre-miRNA into the immunoglobulin heavy-chain locus genetics_knock down_promote hsa-mir-15a Leukemia 16166262 the deletion or downregulation of mir-15a results in increased expression of BCL2. genetics_knock down_promote hsa-mir-15a Lymphoma 16166262 the deletion or downregulation of mir-15a results in increased expression of BCL2. genetics_knock down_promote hsa-mir-16-1 Leukemia 16166262 the deletion or downregulation of mir-15a results in increased expression of BCL2. genetics_knock down_promote hsa-mir-16-1 Lymphoma 16166262 the deletion or downregulation of mir-15a results in increased expression of BCL2. genetics_knock down_promote hsa-mir-125b-1 "Leukemia, B-Cell" 16885332 "In a precursor B-cell acute lymphoblastic leukemia, an insertion of miR-125b-1 into a rearranged immunoglobulin heavy chain locus was described." genetics_knock down_promote hsa-mir-142 "Leukemia, B-Cell" 16885332 It was shown later that miR-142 is located at the chromosome 17 breakpoint and that c-Myc was rearranged under the control of the promoter of miR-142 with consequent overexpression. genetics_knock down_promote hsa-mir-15a "Leukemia, B-Cell" 16885332 Deleted and down-regulated in the majority of B-CLLs genetics_knock down_promote hsa-mir-15a Pituitary Neoplasms 16885332 a type of benign tumors displaying deletions at 13q14.3 and reduced expression of miR-16-1 and miR-15a genetics_knock down_promote hsa-mir-16-1 "Leukemia, B-Cell" 16885332 Deleted and down-regulated in the majority of B-CLLs genetics_knock down_promote hsa-mir-16-1 Pituitary Neoplasms 16885332 a type of benign tumors displaying deletions at 13q14.3 and reduced expression of miR-16-1 and miR-15a genetics_knock down_promote hsa-mir-17 Breast Neoplasms 16940181 "The genomic location of Mir-17-5p also undergoesloss of heterozygosity in different types of cancer, including breast cancer." genetics_knock down_promote hsa-mir-92a-1 Hematologic Neoplasms 17011485 The miR-17-92 cluster is amplified in hematopoietic malignancies. genetics_knock down_promote hsa-mir-15a Breast Neoplasms 17012848 "Later on, deletion of mir-16-1 and mir-15a deletion were also identified in epithelial tumors, such as pituitary adenomas, ovarian and breast cancer." genetics_knock down_promote hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 17012848 "It was found that mir-16-1 and mir-15a at 13q14 are deleted in more than 50% patients, with concurrent reduced expression in ~65% patients. Further studies demonstrated that these two miRNAs suppress BCL2 expression and may serve as tumor suppressor genes in this disease." genetics_knock down_promote hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 17012848 "It was found that mir-16-1 and mir-15a at 13q14 are deleted in more than 50% patients, with concurrent reduced expression in ~65% patients. Further studies demonstrated that these two miRNAs suppress BCL2 expression and may serve as tumor suppressor genes in this disease." genetics_knock down_promote hsa-mir-16-1 Ovarian Neoplasms 17012848 "Later on, deletion of mir-16-1 and mir-15a deletion were also identified in epithelial tumors, such as pituitary adenomas, ovarian and breast cancer." genetics_knock down_promote hsa-mir-16-1 Pituitary Neoplasms 17012848 "Later on, deletion of mir-16-1 and mir-15a deletion were also identified in epithelial tumors, such as pituitary adenomas, ovarian and breast cancer." genetics_knock down_promote hsa-mir-125b-1 "Leukemia, B-Cell" 17028302 "It is of note that insertion of miR-125b-1 into a rearranged immunoglobulin heavy chain gene locus was recently reported in a patient with precursor B-cell acute lymphoblastic leukemia, though the expression miR-125b-1 was not investigated." genetics_knock down_promote hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 17028302 "Detailed analyses of deletion and expression status revealed these two miRNAs to be located within a 30 kb minimally deleted region in chronic lymphocytic leukemia (CLL) patients, both of which were deleted or downregulated in most CLL cases, suggesting that miR-15a and miR-16-1 may function as tumor suppressor genes." genetics_knock down_promote hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 17028302 "Detailed analyses of deletion and expression status revealed these two miRNAs to be located within a 30 kb minimally deleted region in chronic lymphocytic leukemia (CLL) patients, both of which were deleted or downregulated in most CLL cases, suggesting that miR-15a and miR-16-1 may function as tumor suppressor genes." genetics_knock down_promote hsa-mir-199a-1 "Carcinoma, Hepatocellular" 17188425 "This region encodes miRNA-199a-1 (19p13.2), whose expression levels are lower in HCC compared to nontumor liver [59] and is deleted in several other tumor types." genetics_knock down_promote hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 17234972 "After years of futile attemptsto identify the gene(s) in the deleted 13q14 region that participatein the pathogenesis of chronic lymphocytic leukemia, Calin etal discovered that miR-15 and miR-16 are located within thissequence and that both are downregulated in 68% of cases." genetics_knock down_promote hsa-mir-15b "Leukemia, Lymphocytic, Chronic, B-Cell" 17234972 "After years of futile attemptsto identify the gene(s) in the deleted 13q14 region that participatein the pathogenesis of chronic lymphocytic leukemia, Calin etal discovered that miR-15 and miR-16 are located within thissequence and that both are downregulated in 68% of cases." genetics_knock down_promote hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 17234972 "After years of futile attemptsto identify the gene(s) in the deleted 13q14 region that participatein the pathogenesis of chronic lymphocytic leukemia, Calin etal discovered that miR-15 and miR-16 are located within thissequence and that both are downregulated in 68% of cases." genetics_knock down_promote hsa-mir-16-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 17234972 "After years of futile attemptsto identify the gene(s) in the deleted 13q14 region that participatein the pathogenesis of chronic lymphocytic leukemia, Calin etal discovered that miR-15 and miR-16 are located within thissequence and that both are downregulated in 68% of cases." genetics_knock down_promote hsa-mir-181b-2 Urinary Bladder Cancer 17470785 "mir-181b-2 and mir-199b are 3.3 Mb from the peak of the colon Scc2 locus on Chr 2; homologous human miRNAs are located inside a cancer-associated genomic region, which is a region commonly deleted in bladder cancer." genetics_knock down_promote hsa-mir-199b Urinary Bladder Cancer 17470785 "mir-181b-2 and mir-199b are 3.3 Mb from the peak of the colon Scc2 locus on Chr 2; homologous human miRNAs are located inside a cancer-associated genomic region, which is a region commonly deleted in bladder cancer." genetics_knock down_promote hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 17531469 "The loss-of-function of miR-15a and miR-16-1 in CLL, and perhaps other cancers as well, may contribute to malignant transformation by upregulating Bcl2 thereby preventing apoptosis." genetics_knock down_promote hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 17531469 "the loss-of-function of miR-15a and miR-16-1 in CLL, and perhaps other cancers as well, may contribute to malignant transformation by upregulating Bcl2 thereby preventing apoptosis." genetics_knock down_promote hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 17940623 "The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells." genetics_knock down_promote hsa-mir-15a "Lymphoma, Mantle-Cell" 17940623 "The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells." genetics_knock down_promote hsa-mir-15a Multiple Myeloma 17940623 "The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells." genetics_knock down_promote hsa-mir-15a Prostate Neoplasms 17940623 "The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells." genetics_knock down_promote hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 17940623 "The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells." genetics_knock down_promote hsa-mir-16-1 "Lymphoma, Mantle-Cell" 17940623 "The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells." genetics_knock down_promote hsa-mir-16-1 Multiple Myeloma 17940623 "The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells." genetics_knock down_promote hsa-mir-16-1 Prostate Neoplasms 17940623 "The common loss of miR-15a and miR-16-1 in CLL, as well as the loss of 13q14 in mantle cell lymphoma (50 percent of cases), multiple myeloma (16 to 40 percent) and prostate cancer (60 percent), strongly suggests that these two miRNAs act as tumor suppressor genes. While their full target complement is unknown, they appear to mediate their effects largely by down-regulating the anti-apoptotic protein BCL2. This protein is often found expressed at high levels in CLL and is thought to be important for the survival of the malignant cells." genetics_knock down_promote hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 17965831 "miR-15a and miR-16 are often deleted from chromosome 13q14.2 in patients with B cell CLL, suggesting that these miRNAs may be involved in tumour suppression. Additionally, introduction of exogenous miR-16 into a malignant B-1 cell line resulted in increased apoptosis." genetics_knock down_promote hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 17965831 "miR-15a and miR-16 are often deleted from chromosome 13q14.2 in patients with B cell CLL, suggesting that these miRNAs may be involved in tumour suppression. Additionally, introduction of exogenous miR-16 into a malignant B-1 cell line resulted in increased apoptosis." genetics_knock down_promote hsa-mir-16-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 17965831 "miR-15a and miR-16 are often deleted from chromosome 13q14.2 in patients with B cell CLL, suggesting that these miRNAs may be involved in tumour suppression. Additionally, introduction of exogenous miR-16 into a malignant B-1 cell line resulted in increased apoptosis." genetics_knock down_promote hsa-mir-29a Alzheimer Disease 18434550 loss genetics_knock down_promote hsa-mir-29b-1 Alzheimer Disease 18434550 loss genetics_knock down_promote hsa-mir-1-1 "Carcinoma, Hepatocellular" 18593903 miR-1: silenced genetics_knock down_promote hsa-mir-1-2 "Carcinoma, Hepatocellular" 18593903 miR-1: silenced genetics_knock down_promote hsa-mir-34a Neoplasms [unspecific] 18834855 miR-34a: reduced or lost genetics_knock down_promote hsa-mir-101-1 Neoplasms [unspecific] 19008416 miR-101: Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer genetics_knock down_promote hsa-mir-101-2 Neoplasms [unspecific] 19008416 miR-101: Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer genetics_knock down_promote hsa-mir-31 Neoplasms [unspecific] 20179198 miR-31 is associated with defects in the p53 pathway and functions in serous ovarian cancer and other cancers genetics_knock down_promote hsa-mir-31 Ovarian Neoplasms 20179198 miR-31 is associated with defects in the p53 pathway and functions in serous ovarian cancer and other cancers genetics_knock down_promote hsa-mir-143 Neoplasms [unspecific] 20439436 miR-143:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted genetics_knock down_promote hsa-mir-145 Neoplasms [unspecific] 20439436 miR-145:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted genetics_knock down_promote hsa-mir-31 Mesothelioma 20463022 miR-31:Pro-tumorigenic effects of miR-31 loss in mesothelioma genetics_knock down_promote hsa-mir-301a Lung Neoplasms 20470754 "miR-301:blocking of miR-301 in A549 cells leads to a decrease in the expression of the host gene, ska2" genetics_knock down_promote hsa-mir-29a "Leukemia, Myeloid, Acute" 20628397 miR-29a:The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML genetics_knock down_promote hsa-mir-29b-1 "Leukemia, Myeloid, Acute" 20628397 miR-29b1:The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML genetics_knock down_promote hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 21156224 often absent genetics_knock down_promote hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 21156224 often absent genetics_knock down_promote hsa-mir-107 Urinary Bladder Cancer 21388952 Specific deletion of p53 in urothelial cells is associated with specific overexpression of miR-18a and miR-19a and down-regulation of miR-107. genetics_knock down_promote hsa-mir-486 Gastric Neoplasms 21415212 Genomic Loss of miR-486 Regulates Tumor Progression and the OLFM4 Anti-apoptotic Factor in Gastric Cancer. genetics_knock down_promote hsa-mir-15a Prostate Neoplasms 21472816 The miR-15a-miR-16-1 locus is homozygously deleted in a subset of prostate cancers. genetics_knock down_promote hsa-mir-16-1 Prostate Neoplasms 21472816 The miR-15a-miR-16-1 locus is homozygously deleted in a subset of prostate cancers. genetics_knock down_promote hsa-mir-218-1 Urinary Bladder Cancer 21519788 miR-218 on the genomic loss region of chromosome 4p15.31 functions as a tumor suppressor in bladder cancer. genetics_knock down_promote hsa-mir-218-2 Urinary Bladder Cancer 21519788 miR-218 on the genomic loss region of chromosome 4p15.31 functions as a tumor suppressor in bladder cancer. genetics_knock down_promote hsa-mir-1-1 Myotonic Muscular Dystrophy 21685920 "As a consequence of miR-1 loss, expression of GJA1 (connexin 43) and CACNA1C (Cav1.2), which are targets of miR-1, is increased in both DM1- and DM2-affected hearts." genetics_knock down_promote hsa-mir-1-2 Myotonic Muscular Dystrophy 21685920 "As a consequence of miR-1 loss, expression of GJA1 (connexin 43) and CACNA1C (Cav1.2), which are targets of miR-1, is increased in both DM1- and DM2-affected hearts." genetics_knock down_promote hsa-mir-135a-1 Medulloblastoma 21793975 deletion genetics_knock down_promote hsa-mir-135a-2 Medulloblastoma 21793975 deletion or amplification genetics_knock down_promote hsa-mir-135b Medulloblastoma 21793975 deletion or amplification genetics_knock down_promote hsa-mir-186 Medulloblastoma 21793975 deletion genetics_knock down_promote hsa-mir-33b Medulloblastoma 21793975 "deletion, amplification or a mutation at the precursor miRNA" genetics_knock down_promote hsa-mir-512-2 Medulloblastoma 21793975 "deletion. Antisense-based knockdown of miR-512-5p (mature sequence of miR-512-2) resulted in significant upregulation of MYCC expression in HeLa and A549 cells, while forced overexpression of miR-512-2 in medulloblastoma/PNET cell lines DAOY, UW-228-2, PFSK resulted in downregulation of MYCC protein." genetics_knock down_promote hsa-mir-548d-1 Medulloblastoma 21793975 deletion genetics_knock down_promote hsa-mir-548d-2 Medulloblastoma 21793975 deletion genetics_knock down_promote hsa-mir-132 Progressive Supranuclear Palsy 21807765 "MicroRNA-132 loss is associated with tau exon 10 inclusion in Supranuclear Palsy, Progressive." genetics_knock down_promote hsa-mir-101-1 Lung Neoplasms 21849855 miR-101 DNA Copy Loss is a Prominent Subtype Specific Event in Lung Cancer. genetics_knock down_promote hsa-mir-101-2 Lung Neoplasms 21849855 miR-101 DNA Copy Loss is a Prominent Subtype Specific Event in Lung Cancer. genetics_knock down_promote hsa-mir-145 Myelodysplastic Syndromes 21873545 miR-145 affects megakaryocyte and erythroid differentiation.Patients with del(5q) MDS have decreased expression of miR-145 and increased expression of Fli-1. Combined loss of miR-145 and RPS14 cooperate to alter erythroid-megakaryocytic differentiation in a manner similar to the 5q- syndrome. genetics_knock down_promote hsa-mir-17 Musculoskeletal Abnormalities [unspecific] 21892160 Germline deletion of the miR-17-92 cluster causes skeletal and growth defects in humans. genetics_knock down_promote hsa-mir-18a Musculoskeletal Abnormalities [unspecific] 21892160 Germline deletion of the miR-17-92 cluster causes skeletal and growth defects in humans. genetics_knock down_promote hsa-mir-19a Musculoskeletal Abnormalities [unspecific] 21892160 Germline deletion of the miR-17-92 cluster causes skeletal and growth defects in humans. genetics_knock down_promote hsa-mir-19b-1 Musculoskeletal Abnormalities [unspecific] 21892160 Germline deletion of the miR-17-92 cluster causes skeletal and growth defects in humans. genetics_knock down_promote hsa-mir-20a Musculoskeletal Abnormalities [unspecific] 21892160 Germline deletion of the miR-17-92 cluster causes skeletal and growth defects in humans. genetics_knock down_promote hsa-mir-92a-1 Musculoskeletal Abnormalities [unspecific] 21892160 Germline deletion of the miR-17-92 cluster causes skeletal and growth defects in humans. genetics_knock down_promote hsa-mir-21 Hypertension 21920918 "Induction of miR-21 and miR-27a may be a critical component of BMP-induced growth suppression, loss of which likely contributes to vascular cell proliferation in HPAH (Heritable pulmonary arterial hypertension)." genetics_knock down_promote hsa-mir-101-1 Pancreatic Neoplasms 21932133 Loss of MicroRNA-101 Promotes Overexpression of Histone Methyltransferase EZH2. genetics_knock down_promote hsa-mir-101-2 Pancreatic Neoplasms 21932133 Loss of MicroRNA-101 Promotes Overexpression of Histone Methyltransferase EZH2. genetics_knock down_promote hsa-mir-101-1 "Carcinoma, Lung, Non-Small-Cell" 21993632 "Down-regulation of miR-101 was associated with overexpression of Mcl-1 mRNA in NSCLC tissue when compared with corresponding normal tissue, with a negative correlation (r = -0.724, P < 0.01). MiR-101 expression was significantly associated with pathological stage (P = 0.004) and lymph node involvement (P = 0.012). Overexpression of Mcl-1 was associated with pathological grade (P = 0.022) and lymph node involvement (P = 0.017). A comparison of survival curves of low versus high expressers of miR-101 and Mcl-1 revealed a highly significant difference in NSCLC (P < 0.05), which suggests that reduced expression of miR-101 versus overexpression of Mcl-1 is associated with a poorer prognosis." genetics_knock down_promote hsa-mir-101-2 "Carcinoma, Lung, Non-Small-Cell" 21993632 "Down-regulation of miR-101 was associated with overexpression of Mcl-1 mRNA in NSCLC tissue when compared with corresponding normal tissue, with a negative correlation (r = -0.724, P < 0.01). MiR-101 expression was significantly associated with pathological stage (P = 0.004) and lymph node involvement (P = 0.012). Overexpression of Mcl-1 was associated with pathological grade (P = 0.022) and lymph node involvement (P = 0.017). A comparison of survival curves of low versus high expressers of miR-101 and Mcl-1 revealed a highly significant difference in NSCLC (P < 0.05), which suggests that reduced expression of miR-101 versus overexpression of Mcl-1 is associated with a poorer prognosis." genetics_knock down_promote hsa-mir-144 Thyroid Neoplasms 22049245 miR-199b-5p and miR-144 which were essentially lost in the carcinomas. genetics_knock down_promote hsa-mir-199b Thyroid Neoplasms 22049245 miR-199b-5p and miR-144 which were essentially lost in the carcinomas. genetics_knock down_promote hsa-mir-29a Kidney Diseases [unspecific] 22095944 Suppression of microRNA-29 Expression by TGF-beta1 Promotes Collagen Expression and Renal Fibrosis. genetics_knock down_promote hsa-mir-29b-1 Kidney Diseases [unspecific] 22095944 Suppression of microRNA-29 Expression by TGF-beta1 Promotes Collagen Expression and Renal Fibrosis. genetics_knock down_promote hsa-mir-29b-2 Kidney Diseases [unspecific] 22095944 Suppression of microRNA-29 Expression by TGF-beta1 Promotes Collagen Expression and Renal Fibrosis. genetics_knock down_promote hsa-mir-29c Kidney Diseases [unspecific] 22095944 Suppression of microRNA-29 Expression by TGF-beta1 Promotes Collagen Expression and Renal Fibrosis. genetics_knock down_promote hsa-mir-122 Hepatitis B Virus Infection 22105316 Loss of MiR-122 expression in patients with hepatitis B enhances hepatitis B virus replication through cyclin G1 modulated P53 activity. genetics_knock down_promote hsa-mir-34a Rheumatoid Arthritis 22161761 Downregulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance. genetics_knock down_promote hsa-mir-124-1 Glioma 22253443 Loss of brain-enriched miR-124 enhances the stem-like traits and invasiveness of glioma cells. genetics_knock down_promote hsa-mir-124-2 Glioma 22253443 Loss of brain-enriched miR-124 enhances the stem-like traits and invasiveness of glioma cells. genetics_knock down_promote hsa-mir-124-3 Glioma 22253443 Loss of brain-enriched miR-124 enhances the stem-like traits and invasiveness of glioma cells. genetics_knock down_promote hsa-mir-145 Ovarian Neoplasms 22285623 The loss of miR-145 can result in the activation of factors that promote oncogenesis and cellular pluripotency which in turn could lead to the development of ovarian cancer. genetics_knock down_promote hsa-mir-133a-1 Breast Neoplasms 22292984 Loss of miR-133a expression associated with poor survival of breast cancer and restoration of miR-133a expression inhibited breast cancer cell growth and invasion. genetics_knock down_promote hsa-mir-133a-2 Breast Neoplasms 22292984 Loss of miR-133a expression associated with poor survival of breast cancer and restoration of miR-133a expression inhibited breast cancer cell growth and invasion. genetics_knock down_promote hsa-mir-29a "Muscular Dystrophy, Duchenne" 22434133 Loss of miR-29 in Myoblasts Contributes to Dystrophic Muscle Pathogenesis. genetics_knock down_promote hsa-mir-29b-1 "Muscular Dystrophy, Duchenne" 22434133 Loss of miR-29 in Myoblasts Contributes to Dystrophic Muscle Pathogenesis. genetics_knock down_promote hsa-mir-29b-2 "Muscular Dystrophy, Duchenne" 22434133 Loss of miR-29 in Myoblasts Contributes to Dystrophic Muscle Pathogenesis. genetics_knock down_promote hsa-mir-29c "Muscular Dystrophy, Duchenne" 22434133 Loss of miR-29 in Myoblasts Contributes to Dystrophic Muscle Pathogenesis. genetics_knock down_promote hsa-mir-101-1 Gastric Neoplasms 22450781 Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 upregulation in intestinal gastric cancer. genetics_knock down_promote hsa-let-7c Prostate Neoplasms 22479342 MicroRNA let-7c Is Downregulated in Prostate Cancer and Suppresses Prostate Cancer Growth. genetics_knock down_promote hsa-mir-205 Melanoma 22525428 Loss of microRNA-205 expression is associated with melanoma progression. genetics_knock down_promote hsa-let-7g Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. genetics_knock down_promote hsa-mir-126 Pancreatic Neoplasms 22845403 Loss of miR-126 is crucial to pancreatic cancer progression. genetics_knock down_promote hsa-mir-148a Endometrial Neoplasms 22890324 Silencing of miR-148a in cancer-associated fibroblasts results in WNT10B-mediated stimulation of tumor cell motility. genetics_knock down_promote hsa-mir-218-1 Breast Neoplasms 22898079 Silencing of miRNA-218 promotes migration and invasion of breast cancer via Slit2-Robo1 pathway. genetics_knock down_promote hsa-mir-218-2 Breast Neoplasms 22898079 Silencing of miRNA-218 promotes migration and invasion of breast cancer via Slit2-Robo1 pathway. genetics_knock down_promote hsa-mir-101-1 Colon Neoplasms 22930392 Loss of miR-101 Expression Promotes Wnt/beta-Catenin Signalling Pathway Activation and Malignancy in Colon Cancer Cells. genetics_knock down_promote hsa-mir-200a Melanoma 22956368 "Loss of microRNA-200a and c, and microRNA-203 expression at the invasive front of primary cutaneous melanoma is associated with increased thickness and disease progression." genetics_knock down_promote hsa-mir-200c Melanoma 22956368 "Loss of microRNA-200a and c, and microRNA-203 expression at the invasive front of primary cutaneous melanoma is associated with increased thickness and disease progression." genetics_knock down_promote hsa-mir-203 Melanoma 22956368 "Loss of microRNA-200a and c, and microRNA-203 expression at the invasive front of primary cutaneous melanoma is associated with increased thickness and disease progression." genetics_knock down_promote hsa-mir-370 Cholangiocarcinoma 23110045 Silencing of miR-370 in human cholangiocarcinoma by allelic loss and interleukin-6 induced maternal to paternal epigenotype switch genetics_knock down_promote hsa-mir-126 Heart Failure 23136161 Loss of AngiomiR-126 and 130a in Angiogenic Early Outgrowth Cells From Patients With Chronic Heart Failure: Role for Impaired In Vivo Neovascularization and Cardiac Repair Capacity genetics_knock down_promote hsa-mir-130a Heart Failure 23136161 Loss of AngiomiR-126 and 130a in Angiogenic Early Outgrowth Cells From Patients With Chronic Heart Failure: Role for Impaired In Vivo Neovascularization and Cardiac Repair Capacity genetics_knock down_promote hsa-mir-204 Glioma 23204229 Loss of miR-204 Expression Enhances Glioma Migration and Stem Cell-like Phenotype genetics_knock down_promote hsa-mir-132 Osteosarcoma 23801049 Loss of microRNA-132 predicts poor prognosis in patients with primary osteosarcoma. genetics_knock down_promote hsa-let-7 Prostate Neoplasms 23977098 "MSCs co-evolve with prostate cancer cells in the tumor microenvironment, and the downregulation of let-7 by cancer-associated MSCs upregulates IL-6 expression." genetics_knock down_promote hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 24026141 "There was a significantly decreased expression of both miRNAs in patients with biallelic deletion of the 13q14 region but only when deletions were present in 77% or more of cells, as detected by fluorescent in situ hybridization (FISH)." genetics_knock down_promote hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 24026141 "There was a significantly decreased expression of both miRNAs in patients with biallelic deletion of the 13q14 region but only when deletions were present in 77% or more of cells, as detected by fluorescent in situ hybridization (FISH)." genetics_knock down_promote hsa-mir-21 Ischemia-Reperfusion Injury 24098402 Our data clearly demonstrate that miR-21 is involved in IPost-mediated cardiac protection against I/R injury and dysfunction through the PTEN/Akt signaling pathway in vivo. genetics_knock down_promote hsa-mir-10a Neoplasms [unspecific] 24204315 Loss of miR-10a activates lpo and collaborates with activated Wnt signaling in inducing intestinal neoplasia in female mice. genetics_knock down_promote hsa-mir-200a Breast Neoplasms 24280074 Loss of microRNA-200a expression correlates with tumor progression in breast cancer. genetics_knock down_promote hsa-mir-126 Prostate Neoplasms 24350576 These findings suggest for the first time that the loss of miR-126 expression may play a positive role in the malignant progression of PCa. genetics_knock down_promote hsa-mir-214 "Carcinoma, Nasopharyngeal" 24465927 Knockdown of miR-214 promotes apoptosis and inhibits cell proliferation in nasopharyngeal carcinoma. genetics_knock down_promote hsa-mir-223 Sepsis 24486439 "Taken together, these data indicate that loss of miR-223/-223* causes an aggravation of sepsis-induced inflammation, myocardial dysfunction and mortality." genetics_knock down_promote hsa-mir-206 Amyotrophic Lateral Sclerosis 24664281 "in mutant mice lacking miR-206, reinnervation is impaired following nerve injury and loss of NMJs is accelerated in a mouse model of amyotrophic lateral sclerosis (ALS)." genetics_knock down_promote hsa-mir-145 "Carcinoma, Hepatocellular" 24690171 "Our results demonstrated that miR-145 could inhibit HCC through targeting IRS1 and its downstream signaling, implicating the loss of miR-145 regulation may be a potential molecular mechanism causing aberrant oncogenic signaling in HCC." genetics_knock down_promote hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 24732594 Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia. genetics_knock down_promote hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 24732594 Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia. genetics_knock down_promote hsa-mir-21 Pulmonary Hypertension 24732886 "In vivo, genetic deletion of microRNA-21 in mice (miR-21(-/-) mice) resulted in functional activation of the PDCD4/caspase-3 axis in the pulmonary tissues, leading to the onset of progressive PH." genetics_knock down_promote hsa-mir-424 Hepatoblastoma 24796297 "Furthermore, miR-424 or miR-503 depletion enhanced extravasation to the lungs of hepatocarcinoma cells injected in the tail vein of mice." genetics_knock down_promote hsa-mir-100 Prostate Neoplasms 24805183 "Loss of miR-100 enhances migration, invasion, epithelial-mesenchymal transition and stemness properties in prostate cancer cells through targeting Argonaute 2." genetics_knock down_promote hsa-mir-451a "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 24918822 Loss of tumour suppressive miR-451a enhanced cancer cell migration and invasion in HSCC through direct regulation of ESDN. Our miRNA signature and functional analysis of targets regulated by tumour suppressive miR-451a provide new insights into the potential mechanisms of HSCC oncogenesis and metastasis. genetics_knock down_promote hsa-mir-17 Atrial Fibrillation 24927531 "miR-17-92 and miR-106b-25 directly repress genes, such as Shox2 and Tbx3, that are required for sinoatrial node development.Together, to our knowledge, these findings provide the first genetic evidence for an miR loss-of-function that increases atrial fibrillation susceptibility." genetics_knock down_promote hsa-mir-18 Atrial Fibrillation 24927531 "miR-17-92 and miR-106b-25 directly repress genes, such as Shox2 and Tbx3, that are required for sinoatrial node development.Together, to our knowledge, these findings provide the first genetic evidence for an miR loss-of-function that increases atrial fibrillation susceptibility." genetics_knock down_promote hsa-mir-19a Atrial Fibrillation 24927531 "miR-17-92 and miR-106b-25 directly repress genes, such as Shox2 and Tbx3, that are required for sinoatrial node development.Together, to our knowledge, these findings provide the first genetic evidence for an miR loss-of-function that increases atrial fibrillation susceptibility." genetics_knock down_promote hsa-mir-19b-1 Atrial Fibrillation 24927531 "miR-17-92 and miR-106b-25 directly repress genes, such as Shox2 and Tbx3, that are required for sinoatrial node development.Together, to our knowledge, these findings provide the first genetic evidence for an miR loss-of-function that increases atrial fibrillation susceptibility." genetics_knock down_promote hsa-mir-20a Atrial Fibrillation 24927531 "miR-17-92 and miR-106b-25 directly repress genes, such as Shox2 and Tbx3, that are required for sinoatrial node development.Together, to our knowledge, these findings provide the first genetic evidence for an miR loss-of-function that increases atrial fibrillation susceptibility." genetics_knock down_promote hsa-mir-92-1 Atrial Fibrillation 24927531 "miR-17-92 and miR-106b-25 directly repress genes, such as Shox2 and Tbx3, that are required for sinoatrial node development.Together, to our knowledge, these findings provide the first genetic evidence for an miR loss-of-function that increases atrial fibrillation susceptibility." genetics_knock down_promote hsa-mir-203 Prostate Neoplasms 24980827 Loss of tumor suppressor mir-203 mediates overexpression of LIM and SH3 Protein 1 (LASP1) in high-risk prostate cancer thereby increasing cell proliferation and migration. genetics_knock down_promote hsa-mir-155 Melanoma 25143000 Our current study showed that both B16-F10 melanoma and Lewis lung carcinoma tumors grew much faster in bic/miR-155 knockout (miR-155(-/-) ) mice genetics_knock down_promote hsa-mir-378 Prostate Neoplasms 25153390 "Loss of miR-378 in prostate cancer, a common regulator of KLK2 and KLK4, correlates with aggressive disease phenotype and predicts the short-term relapse of the patients." genetics_knock down_promote hsa-mir-100 "Carcinoma, Hepatocellular" 25361001 Downregulation of microRNA-100 enhances the ICMT-Rac1 signaling and promotes metastasis of hepatocellular carcinoma cells. genetics_knock down_promote hsa-mir-101 "Carcinoma, Esophageal" 25400732 decreased expression of miR-101 might promote metastasis of human ESCC by inducing accumulation of EZH2 protein. genetics_knock down_promote hsa-mir-101 Lung Neoplasms 25428391 "particle can induce the secretion of interleukin-1¦Â. Interleukin-1¦Â subsequently induces the downregulation of mir-101, which may result in the upregulated level of EZH2, and occurrence of lung cancer. We for the first time proposed the role interleukin-1¦Â-mir-101-EZH2 axes in the particle-induced lung cancer. Further study may be needed to decipher the detailed mechanism involved." genetics_knock down_promote hsa-mir-34a Prostate Neoplasms 25436980 "the bone metastasis and anti-apoptotic effects found in Ras signaling-activated prostate cancer cells require miR-34a deficiency, which in turn aids in cell survival by activating the WNT and anti-apoptotic signaling pathways thereby inducing TCF7 and BIRC5 expressions." genetics_knock down_promote hsa-mir-34a Diabetes Mellitus 25483877 "Knockdown of miR-34a slightly decreased proliferation, but as apoptosis and NO synthesis were highly reduced, miR-34a may be further investigated as a therapeutic target to reduce β-cell death and dysfunction." genetics_knock down_promote hsa-mir-7 Breast Neoplasms 25532106 Suppression of miR-7 in the MCF-7 cell line resulted in enhanced colony formation activity but not cell migration genetics_knock down_promote hsa-mir-204 Prostate Neoplasms 25630658 "not only tumor suppressor micro-RNA loss, but also significant genome rearrangement-driven regulatory loop perturbations play a role in the advanced cancer progression, conferring better pro-survival and metastatic potential." genetics_knock down_promote hsa-mir-26a Neoplasms [unspecific] 25668004 Loss of tumour-suppressive miR-26a/b enhanced cancer cell migration and invasion in OSCC through direct regulation of TMEM184B. Our data describing pathways regulated by tumour-suppressive miR-26a/b provide new insights into the potential mechanisms of OSCC oncogenesis and metastasis. genetics_knock down_promote hsa-mir-26b Neoplasms [unspecific] 25668004 Loss of tumour-suppressive miR-26a/b enhanced cancer cell migration and invasion in OSCC through direct regulation of TMEM184B. Our data describing pathways regulated by tumour-suppressive miR-26a/b provide new insights into the potential mechanisms of OSCC oncogenesis and metastasis. genetics_knock down_promote hsa-mir-1 Prostate Neoplasms 25802280 Our data support the existence of an AR-miR-1-SRC regulatory network.We propose that loss of miR-1 is one mechanistic link between low canonical Androgen receptor (AR) output and SRC-promoted metastatic phenotypes. genetics_knock down_promote hsa-mir-23a Idiopathic Pulmonary Hypertension 25815108 "Finally we found that silencing of miR23a resulted in an increase of the expression of PGC1¦Á, as well as in its well-known regulated genes CYC, SOD, NRF2,and HO1. The results point to the utility of circulating miRNA expression as a biomarker of disease progression." genetics_knock down_promote hsa-mir-146b "Carcinoma, Thyroid, Papillary" 25819770 "The results showed that PTC cells overexpress miR-146b and miR-222 in exosomes; and that factors released by both normal thyroid and PTC cells alter proliferation of other cells in a complex manner. The intercellular interactions were likely conferred in part by exosomal miRNA, which can potentially be developed as biomarkers of PTC recurrence." genetics_knock down_promote hsa-mir-222 "Carcinoma, Thyroid, Papillary" 25819770 "The results showed that PTC cells overexpress miR-146b and miR-222 in exosomes; and that factors released by both normal thyroid and PTC cells alter proliferation of other cells in a complex manner. The intercellular interactions were likely conferred in part by exosomal miRNA, which can potentially be developed as biomarkers of PTC recurrence." genetics_knock down_promote hsa-mir-150 Heart Failure 25824147 we show that genetic deletion of miR-150 in mice causes abnormalities in cardiac structural and functional remodelling after MI. genetics_knock down_promote hsa-mir-150 Myocardial Infarction 25824147 we show that genetic deletion of miR-150 in mice causes abnormalities in cardiac structural and functional remodelling after MI. genetics_knock down_promote hsa-mir-155 "Lymphoma, B-Cell" 25829072 "A deficiency of miR-155 in the immune system causes attenuated immune functions. Clinically, several types of malignancy including diffuse large B-cell lymphoma have high miR-155 expression levels." genetics_knock down_promote hsa-mir-21 Acute Kidney Failure 25844699 "Knockdown of miR-21 upregulated its target effectors programmed cell death protein 4 and phosphatase and tensin homolog deleted on chromosome 10 expression, resulted in an increase in apoptosis, and exacerbated lipopolysaccharide-induced acute kidney injury." genetics_knock down_promote hsa-mir-155 Mycobacterium tuberculosis Infection 25846955 "Following infection, miR-155-deficient C57BL/6 mice died significantly earlier and had significantly higher numbers of CFU in lungs than wild-type mice." genetics_knock down_promote hsa-mir-377 Lymphoma 25889255 Our results suggest that miR-377 is an important negative regulator of E2F and MAP3K7/NF-kB signaling pathway in melanoma cells; it is tempting to speculate that its silencing in melanoma promotes the tumorigenic and metastatic potential of the cells through activation of these pathways. genetics_knock down_promote hsa-mir-142 Primary Immunodeficiency Disease 25931583 "miR-142 as an essential regulator of lymphopoiesis, and suggest that lesions in this miRNA gene may lead to primary immunodeficiency." genetics_knock down_promote hsa-mir-132 Inflammation 26052826 Blockage of miR-132 using miR-132 inhibitor reversed the Ach action upon LPS-induced release of inflammatory mediators and reduction in AchE protein/activity. genetics_knock down_promote hsa-mir-205 Prostate Neoplasms 26059417 Loss of tumor-suppressive microRNA-205 seems to enhance cancer cell migration and invasion in prostate cancer through direct regulation of centromere protein F. Our data describing pathways regulated by tumor-suppressive microRNA-205 provide new insights into the potential mechanisms of prostate cancer oncogenesis and metastasis. genetics_knock down_promote hsa-mir-133a Heart Failure 26064437 attenuation of miR-133a contributes to the exacerbation of diabetes mediated cardiac autophagy and hypertrophy in heart failure genetics_knock down_promote hsa-mir-133a Hypertrophy 26064437 attenuation of miR-133a contributes to the exacerbation of diabetes mediated cardiac autophagy and hypertrophy in heart failure genetics_knock down_promote hsa-mir-21 "Carcinoma, Hepatocellular" 26282675 "microRNA-21 knockdown led to increased HBP1 and p53 and subsequently reduced lipogenesis and delayed G1/S transition, and the additional treatment of HBP1-siRNA antagonised the effect of microRNA-21-ASO, suggesting that HBP1 mediated the inhibitory effects of microRNA-21-ASO on both hepatic lipid accumulation and hepatocarcinogenesis." genetics_knock down_promote hsa-mir-622 Colorectal Carcinoma 26333174 miR-622 inhibited tumor proliferation and migration in vitro. genetics_knock down_promote hsa-mir-214 Parkinson Disease 26349993 "The loss of miR-214 in PD resulted in the increase of ¦Á-synuclein expression, which was the potential mechanism underlying the neuroprotective effects of Resveratrol." genetics_knock down_promote hsa-mir-195 Cervical Neoplasms 26511972 reducing the endogenous miR-195 level by miR-195 inhibitor promoted the proliferation of cervical cancer cells. genetics_knock down_promote hsa-mir-377 Ischemia-Reperfusion Injury 26564600 "These findings indicate that HF increased miR-377 expression in the myocardium, which is detrimental to stem cell function, and transplantation of miR-377 knockdown hCD34(+) cells into ischemic myocardium promoted their angiogenic ability, attenuating left ventricular remodeling and cardiac fibrosis." genetics_knock down_promote hsa-mir-150 Sepsis 26743170 miR-150(-/-) mice died rapidly after sepsis. genetics_knock down_promote hsa-mir-29b "Carcinoma, Renal Cell" 26823729 "Inhibition of miR-29b expression could promote apoptosis, and inhibit proliferation and invasion ability in SN12-PM6 cells." genetics_knock down_promote hsa-mir-150 Obesity 26833392 miR-150KO mice displayed exacerbated obesity-associated tissue inflammation and systemic insulin resistance genetics_knock down_promote hsa-mir-29c "Carcinoma, Embryonal" 26848028 "Inhibition of miRâ€?9c promoted proliferation, and suppressed the apoptosis and differentiation of P19 cells." genetics_knock down_promote hsa-mir-196a Renal Fibrosis 26940097 depletion of renal miR-196a/b by miR-196a/b antagomirs substantially aggravated UUO-induced renal fibrosis. genetics_knock down_promote hsa-mir-196b Renal Fibrosis 26940097 depletion of renal miR-196a/b by miR-196a/b antagomirs substantially aggravated UUO-induced renal fibrosis. genetics_knock down_promote hsa-mir-126a Sepsis 26968021 "The down-regulation of miR-126a-3p in endothelial cells resulted in the increased apoptosis, and decreased proliferation and migration," genetics_knock down_promote hsa-mir-124 Glioblastoma 26993295 inhibitor of miR-124 promoted the expression of STAT3 and cell proliferation. genetics_knock down_promote hsa-mir-181 Autism Spectrum Disorder 27017280 this loss-of miR-181c function resulted in enhanced neurite sprouting and reduced synaptogenesis genetics_knock down_promote hsa-mir-4282 Colorectal Carcinoma 27120047 "It was found that miR-4282 inhibition promoted cell growth, migration and invasion (P<0.05) of HT29 and HCT116 colorectal carcinoma cells while miR-4282 overexpression suppressed cell growth and mobility (P<0.05)." genetics_knock down_promote hsa-mir-146a Ischemia-Reperfusion Injury 27250735 miR146a exerts a kidney protective effect through negative regulation of acute inflammatory response genetics_knock down_promote hsa-mir-505 "Carcinoma, Hepatocellular" 27259809 "the up-regulation of miR-505 suppressed, whereas the down-regulation of miR-505 promoted proliferation, invasion and epithelial-mesenchymal transition in MHCC97." genetics_knock down_promote hsa-mir-206 Rhabdomyosarcoma 27277678 Genetic deletion of miR-206 in a mouse model of FN-RMS accelerated and exacerbated tumor development genetics_knock down_promote hsa-mir-150 Diabetic Retinopathy 27304911 deletion of miR-150 significantly increased the retinal pathological angiogenesis genetics_knock down_promote hsa-mir-34a Obesity 27377585 miR-34a(-/-) mice are susceptible to diet-induced obesity. genetics_knock down_promote hsa-mir-122 Pterygium 27415790 "Decreased expression of miR-122 in pterygium might result in abnormal cell apoptosis via its regulation of the expression of Bcl-w, and subsequently contribute to the development of pterygium." genetics_knock down_promote hsa-mir-146a Ischemia-Reperfusion Injury 27444565 "After unilateral IRI, miR-146a-/- mice exhibited more extensive tubular injury, inflammatory infiltrates, and fibrosis than wild-type mice." genetics_knock down_promote hsa-mir-145 Prostate Neoplasms 27465939 "ASC-derived conditioned medium (CM) significantly inhibited PC3M-luc2 cell proliferation, inducing apoptosis, but the effect was canceled by miR-145 knockdown in ASCs." genetics_knock down_promote hsa-mir-200b "Squamous Cell Carcinoma, Esophageal" 27496804 "Correlating with the frequent loss of miR-200b in ESCC, both CDK2 and PAF levels are significantly increased in ESCC tumors compared to case-matched normal tissues." genetics_knock down_promote hsa-mir-27a Rheumatoid Arthritis 27498552 "However, miR-27a inhibition promoted the migration and invasion of FLS." genetics_knock down_promote hsa-mir-424 "Carcinoma, Lung, Non-Small-Cell" 27500472 It was found that down-regulation of miR-424-3p was pronouncedly associated with NSCLC progression and overall prognosis; genetics_knock down_promote hsa-let-7 Kaposi Sarcoma 27531260 "Let-7 silencing may activate the replication of KSHV, possibly through up-regulating MAP4K4 and its downstream molecules COX-2, MMP-13, and phosphorylation of ERK1/2, finally results in the progression of Kaposi sarcoma." genetics_knock down_promote hsa-mir-15a Leukemia 27533467 both miR-15a deficient HSC and B1P cells are capable of repopulating irradiated recipients and produce higher numbers of B1 cells than sources with normal miR-15a/16 levels. genetics_knock down_promote hsa-mir-142 "Carcinoma, Hepatocellular" 28177895 Over-expression of Thrombospondin 4 correlates with loss of miR-142 and contributes to migration and vascular invasion of advanced hepatocellular carcinoma. genetics_knock down_promote hsa-mir-7 Hypogonadotropic Hypogonadism 28218624 Loss of microRNA-7a2 induces hypogonadotropic hypogonadism and infertility. genetics_knock down_promote hsa-mir-320a "Carcinoma, Hepatocellular" 28288874 Loss of exosomal miR-320a from cancer-associated fibroblasts contributes to HCC proliferation and metastasis. genetics_knock down_promote hsa-mir-423 Glioma 28381178 miR-423-5p knockdown enhances the sensitivity of glioma stem cells to apigenin through the mitochondrial pathway. genetics_knock down_promote hsa-mir-126 "Carcinoma, Hepatocellular" 28639884 Loss of tumor suppressor miR-126 contributes to the development of hepatitis B virus-related hepatocellular carcinoma metastasis through the upregulation of ADAM9. genetics_knock down_promote hsa-mir-200a "Squamous Cell Carcinoma, Oral" 29480379 lack of significant alterations in miR-31 and miR-200a levels in saliva of OLP patients may be indicative for absence of malignant transformation genetics_knock down_promote hsa-mir-31 "Squamous Cell Carcinoma, Oral" 29480379 lack of significant alterations in miR-31 and miR-200a levels in saliva of OLP patients may be indicative for absence of malignant transformation genetics_knock down_promote hsa-mir-146a Gout 29544526 "miR-146a provides negative feedback regulation of gouty arthritis development and lack of miR-146a enhances gouty arthritis via upregulation of TRAK6, IRAK-1, and the NALP3 inflammasome function" genetics_knock down_promote hsa-mir-15a "Carcinoma, Lung, Non-Small-Cell" 29551936 Knocking down MiR-15a expression promotes the occurrence and development and induces the EMT of NSCLC cells in vitro genetics_knock down_promote hsa-mir-125b "Leukemia, B-Cell" 29555645 physiological silencing of miR-125b is required for normal B-cell development and also acts as a mechanism of cancer suppression genetics_knock down_promote hsa-mir-21 Spinal Cord Injuries 29934690 Knockdown of MicroRNA-21 Promotes Neurological Recovery After Acute Spinal Cord Injury. genetics_knock down_promote hsa-mir-148b Endometrial Neoplasms 30146796 Loss of exosomal miR-148b from cancer-associated fibroblasts promotes endometrial cancer cell invasion and cancer metastasis. genetics_knock down_promote hsa-mir-146b "Leukemia, Lymphoblastic, Acute, T-Cell" 30362152 Loss of miR-146b-5p promotes T cell acute lymphoblastic leukemia migration and invasion via the IL-17A pathway. genetics_knock down_suppress hsa-mir-223 "Leukemia, Promyelocytic, Acute" 16325577 "In line with this, both RNAi against NFI-A and ectopic expression of miR-223 in acute promyelocytic leukemia (APL) cells enhance differentiation, whereas miR-223 knockdown inhibits the differentiation response to RA." genetics_knock down_suppress hsa-mir-1-2 Chronic Heart Failure 17397913 deletion genetics_knock down_suppress hsa-mir-24-1 Tourette Syndrome 17462786 "A mutation in the 3'UTR of the SLITRK1 gene which is associated with Tourette's syndrome was found to enhance repression of the SLITRK mRNA by miR-189, presumably preventing SLITRK1's promotion of dendritic growth." genetics_knock down_suppress hsa-let-7a-1 Colon Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7a-1 Lung Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7a-2 Colon Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7a-2 Lung Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7a-3 Colon Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7a-3 Lung Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7b Colon Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7b Lung Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7c Colon Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7c Lung Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7d Colon Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7d Lung Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7e Colon Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7e Lung Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7f-1 Colon Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7f-1 Lung Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7f-2 Colon Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7f-2 Lung Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7g Colon Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7g Lung Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7i Colon Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-let-7i Lung Neoplasms 17965831 "Furthermore, a reduction in the expression of let-7 was associated with lung cancers and in particular with reduced survival./ Mayr et al. demonstrated that a chromosomal translocation at 12q5 disrupts let-7 expression and consequently curtails inhibition of the oncogene High Mobility Group A2 (Hmga2). Let-7 has also been implicated in the development of colon cancers and the progression of colorectal cancers." genetics_knock down_suppress hsa-mir-221 Carotid Artery Diseases 19150885 miR-221: knockdown of miR-221 and miR-222 in rat carotid arteries suppressed VSMC proliferation in vivo and neointimal lesion formation after angioplasty. The results indicate that miR-221 and miR-222 are novel regulators for VSMC proliferation and neointimal hype genetics_knock down_suppress hsa-mir-222 Carotid Artery Diseases 19150885 miR-222: knockdown of miR-221 and miR-222 in rat carotid arteries suppressed VSMC proliferation in vivo and neointimal lesion formation after angioplasty. The results indicate that miR-221 and miR-222 are novel regulators for VSMC proliferation and neointimal hype genetics_knock down_suppress hsa-mir-10b Myocardial Infarction 19595696 Knockdown of microRNA-181 by lentivirus decreases the arrhythmogenic effect of skeletal myoblast transplantation in rat with myocardial infarction. genetics_knock down_suppress hsa-mir-150 "Carcinoma, Hepatocellular" 19617899 repressed in a subset of primary tumorscharacterized by poor prognosis; loss of miR-122 expression correlates with suppression of the hepatic phenotype and gain of metastatic properties; a diagnostic and prognostic marker genetics_knock down_suppress hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 19744129 "Their aberrant expression has been associated with solid tumors and hematopoietic malignancies as suggested by the frequent deletion of mir-15a and mir-16-1 in chronic lymphocytic leukemia, the increased levels of mir-155 in diffuse large B-cell lymphomas and the increased levels of mir-181 in acute myeloid leukemia M1 and M2. " genetics_knock down_suppress hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 19744129 "Their aberrant expression has been associated with solid tumors and hematopoietic malignancies as suggested by the frequent deletion of mir-15a and mir-16-1 in chronic lymphocytic leukemia, the increased levels of mir-155 in diffuse large B-cell lymphomas and the increased levels of mir-181 in acute myeloid leukemia M1 and M2. " genetics_knock down_suppress hsa-mir-126 Asthma 19843690 Selective blockade of microRNA (miR)-126 suppressed the asthmatic phenotype genetics_knock down_suppress hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 20129242 miR-15a and miR-16-1 were the first microRNAs linked to cancer because their genes are commonly deleted in human chronic lymphocytic leukemia (CLL) genetics_knock down_suppress hsa-let-7a-1 Neoplasms [unspecific] 20614490 let-7a:Gastric carcinoma has relatively lower expression of let-7a genetics_knock down_suppress hsa-let-7a-2 Neoplasms [unspecific] 20614490 let-7a:Gastric carcinoma has relatively lower expression of let-7a genetics_knock down_suppress hsa-let-7a-3 Neoplasms [unspecific] 20614490 let-7a:Gastric carcinoma has relatively lower expression of let-7a genetics_knock down_suppress hsa-mir-200a Neoplasms [unspecific] 20832727 miR-200a:Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells genetics_knock down_suppress hsa-mir-200b Neoplasms [unspecific] 20832727 miR-200b:Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells genetics_knock down_suppress hsa-mir-200c Neoplasms [unspecific] 20832727 miR-200c:Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells genetics_knock down_suppress hsa-mir-21 Breast Neoplasms 21219636 "In vitro assays showed that ERBB2 is a direct target of miR-125a-5p, which potently suppressed the proliferation of gastric cancer cells" genetics_knock down_suppress hsa-mir-221 "Carcinoma, Hepatocellular" 22009537 miR-221 silencing blocks hepatocellular carcinoma and promotes survival. genetics_knock down_suppress hsa-mir-124-1 Neuroblastoma 22024478 "Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR." genetics_knock down_suppress hsa-mir-124-2 Neuroblastoma 22024478 "Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR." genetics_knock down_suppress hsa-mir-124-3 Neuroblastoma 22024478 "Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR." genetics_knock down_suppress hsa-mir-183 "Carcinoma, Thyroid, Medullary" 22024754 MiR-183 knockdown in an MTC cell line (TT cells) reduced cellular proliferation in association with elevated LC3B expression. genetics_knock down_suppress hsa-mir-143 Neoplasms [unspecific] 22330136 Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. genetics_knock down_suppress hsa-mir-145 Neoplasms [unspecific] 22330136 Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. genetics_knock down_suppress hsa-mir-122 Hepatitis C Virus Infection 22898980 The use of an HSP90 inhibitor or knockdown of HSP90 decreased GW182 and miR-122 expression and significantly reduced HCV replication. genetics_knock down_suppress hsa-mir-181b-1 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 22916024 Deletion of mir-181a-1/b-1 expression inhibits the development of Notch1 oncogene-induced T cell acute lymphoblastic leukemia (T-ALL). mir-181a-1/b-1 controls the strength and threshold of Notch activity in tumorigenesis in part by dampening multiple negative feedback regulators downstream of NOTCH and pre-T cell receptor (TCR) signaling pathways. genetics_knock down_suppress hsa-mir-21 Heart Failure 22923342 "Atrial miR-21 knockdown suppresses atrial fibrosis and AF promotion, implicating miR-21 as an important signaling molecule for the AF substrate and pointing to miR-21 as a potential target for molecular interventions designed to prevent AF" genetics_knock down_suppress hsa-let-7i "Carcinoma, Renal Cell" 22926558 "We also validated the prognostic value of miRNA let-7i in RCC. miR-138, located in chromosome 3p deletion, was also found to have suppressive effects on tumor proliferation and migration abilities." genetics_knock down_suppress hsa-mir-138-1 "Carcinoma, Renal Cell" 22926558 "We also validated the prognostic value of miRNA let-7i in RCC. miR-138, located in chromosome 3p deletion, was also found to have suppressive effects on tumor proliferation and migration abilities." genetics_knock down_suppress hsa-mir-138-2 "Carcinoma, Renal Cell" 22926558 "We also validated the prognostic value of miRNA let-7i in RCC. miR-138, located in chromosome 3p deletion, was also found to have suppressive effects on tumor proliferation and migration abilities." genetics_knock down_suppress hsa-mir-21 Glioma 23077620 Silencing of microRNA-21 confers radio-sensitivity through inhibition of the PI3K/AKT pathway and enhancing autophagy in malignant glioma cell lines genetics_knock down_suppress hsa-mir-150 Leukemia 23079661 Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia genetics_knock down_suppress hsa-mir-204 Neoplasms [unspecific] 23285024 Genomic Loss of Tumor Suppressor miRNA-204 Promotes Cancer Cell Migration and Invasion by Activating AKT/mTOR/Rac1 Signaling and Actin Reorganization genetics_knock down_suppress hsa-mir-21 Ischemia-Reperfusion Injury 23681145 "Knockdown of miR-21 induced significant up-regulation of programmed cell death protein 4 and phosphatase and tensin homolog deleted on chromosome 10, two proapoptotic target effectors of miR-21, and resulted in significant down-regulation of phosphorylated protein kinase B and increased tubular cell apoptosis." genetics_knock down_suppress hsa-mir-21 Glioblastoma 23732394 Silencing of miR-21 by locked nucleic acid-lipid nanocapsule complexes sensitize human glioblastoma cells to radiation-induced cell death. genetics_knock down_suppress hsa-mir-18a Immune System Disease [unspecific] 24131405 Treatment of cells with a microRNA-18a mimic in PCPS (PCPS/miR-18) knocked down 90% expression of the microRNA-18a target gene ATM. genetics_knock down_suppress hsa-mir-17 Medulloblastoma 24145352 Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression. genetics_knock down_suppress hsa-mir-19a Medulloblastoma 24145352 Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression. genetics_knock down_suppress hsa-mir-23a "Squamous Cell Carcinoma, Head and Neck" 24317043 Transfection with anti-miR-23a inhibited the proliferation of HN4 cells and induced cell apoptosis. genetics_knock down_suppress hsa-mir-196b "Leukemia, Myeloid, Acute" 24334453 "Therapeutic inhibition of microRNA-21 and microRNA-196b inhibited in vitro leukemic colony forming activity and depleted in vivo leukemia-initiating cell activity of HOX-based leukemias, which led to leukemia-free survival in a murine AML model and delayed disease onset in xenograft models." genetics_knock down_suppress hsa-mir-21 "Leukemia, Myeloid, Acute" 24334453 "Therapeutic inhibition of microRNA-21 and microRNA-196b inhibited in vitro leukemic colony forming activity and depleted in vivo leukemia-initiating cell activity of HOX-based leukemias, which led to leukemia-free survival in a murine AML model and delayed disease onset in xenograft models." genetics_knock down_suppress hsa-mir-92a "Leukemia, Promyelocytic, Acute" 24385779 Down-regulation of miR-92a in APL cell line (HL-60) by LNA antagomir extensively decreased cell viability in APL. genetics_knock down_suppress hsa-let-7b Neoplasms [unspecific] 24423609 Reduction of let-7a3/let-7b miRNA may be one of mechanisms leading to overexpression of HMGA2 in AT/RT tissues. genetics_knock down_suppress hsa-mir-21 Heart Failure 24551276 "After injection of miR-21 antagonist, the the cardiac atrophy and cardiac fibrosis were conspicuously ameliorated." genetics_knock down_suppress hsa-mir-92a "Leukemia, Promyelocytic, Acute" 24627869 The assessment of the apoptosis and necrosis indicates that miR-92a inhibition can decrease the viable HL-60 cells and this is at least partially due to induction of apoptosis. genetics_knock down_suppress hsa-mir-17 Multiple Sclerosis 24644282 T cell-specific miR-17-92 deficiency reduced TH17 differentiation and ameliorated experimental autoimmune encephalomyelitis (EAE) symptoms. genetics_knock down_suppress hsa-mir-155 Encephalomyelitis 24648472 MiR-155 (-/-) mice are highly resistant to experimental autoimmune encephalomyelitis (EAE) genetics_knock down_suppress hsa-mir-18a Prostate Neoplasms 24752237 "Interestingly, miR-18a knockdown decreased cell growth in prostate cancer cells and significantly decreased prostate tumor growth in in vivo nude mice experiments through STK4-mediated dephosphorylation of AKT and thereby inducing apoptosis." genetics_knock down_suppress hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 24804226 Silencing miR-21 sensitizes non-small cell lung cancer A549 cells to ionizing radiation through inhibition of PI3K/Akt. genetics_knock down_suppress hsa-mir-182 Ovarian Neoplasms 24825857 "we found that anti-miR182 treatment can significantly reduce tumor burden (size), local invasion, and distant metastasis compared with its control in both models." genetics_knock down_suppress hsa-mir-17 Medulloblastoma 24928431 "Remarkably, deletion of the miR-17âˆ?2 cluster abolished the development of SHH-MB in Ptch1(+/-) mice." genetics_knock down_suppress hsa-mir-92a Myocardial Ischemic-Reperfusion Injury 24941323 Inhibiting miR-92a can attenuate myocardiocyte apoptosis induced by hypoxia/reoxygenation by targeting Smad7. genetics_knock down_suppress hsa-mir-221 "Carcinoma, Hepatocellular" 24993451 Bioinformatics analysis identifies miR-221 as a core regulator in hepatocellular carcinoma and its silencing suppresses tumor properties. genetics_knock down_suppress hsa-mir-145 Atherosclerosis 25008143 Absence of miR-143/145 significantly reduced atherosclerotic plaque size and macrophage infiltration. genetics_knock down_suppress hsa-mir-21 Lung Neoplasms 25065740 "PHF8 promotes miR-21 expression in human lung cancer, and miR-21 knockdown blocks the effects of PHF8 on proliferation and apoptosis of lung cancer cells." genetics_knock down_suppress hsa-mir-21 Obesity 25141837 "MiR-21 inhibition reduced body weight, as well as adipocyte size and serum triglycerides were significantly decreased." genetics_knock down_suppress hsa-mir-17 "Leukemia, Lymphocytic, Chronic, B-Cell" 25339346 In-vitro administration of antagomiR17 effectively reduced miR-17 expression and the proliferation of CLL-like MEC-1 cells. genetics_knock down_suppress hsa-mir-21 Vascular Disease [unspecific] 25360215 "Low expression of miR-21 significantly inhibited VSMC proliferation, invasion and migration." genetics_knock down_suppress hsa-mir-21 "Leukemia, Lymphoblastic, Acute" 25451263 "Transient inhibition of miR-21 resulted in increased apoptosis, PTEN upregulation and AKT dephosphorylation, whereas ectopic overexpression of miR-21 further conferred imatinib resistance." genetics_knock down_suppress hsa-mir-19b "Carcinoma, Embryonal" 25483911 The results demonstrated that miR-19b knockdown inhibited the proliferation and apoptosis of P19 cells. genetics_knock down_suppress hsa-let-7c Heart Failure 25505600 "Let-7c inhibitor prevented the deterioration of cardiac function postinfarction, as demonstrated by preserved LV ejection fraction and elevated cardiac output." genetics_knock down_suppress hsa-mir-155 Neoplasms [unspecific] 25598954 the proper increase of miR-155 inhibitor concentration can inhibit miR-155 and consequently increase caspase-3 activity and induce apoptosis in the Jurkat cells leading to cell death ultimately. genetics_knock down_suppress hsa-mir-17 "Leukemia, Myeloid, Chronic" 25647305 "Furthermore, overexpression of c-Myc or miR-17/20a alleviated NC induced differentiation and apoptosis in K562 cells." genetics_knock down_suppress hsa-mir-20a "Leukemia, Myeloid, Chronic" 25647305 "Furthermore, overexpression of c-Myc or miR-17/20a alleviated NC induced differentiation and apoptosis in K562 cells." genetics_knock down_suppress hsa-mir-155 Spinal Cord Injuries 25651871 Mir-155 deficiency suppresses Th17 cell differentiation and improves locomotor recovery after SCI. genetics_knock down_suppress hsa-let-7b Neoplasms [unspecific] 25682900 "our findings suggest that let-7b contributes to the fidelity of cell division via regulation of Aurora B. Moreover, the loss of let-7b in aggressive tumors may drive tumorigenesis by up-regulation of Aurora B and other targets of the miRNA, which further supports the role of let-7b in tumor suppression." genetics_knock down_suppress hsa-mir-21 Cholangiocarcinoma 25769721 anti-miR-21 treatment reduced liver tumor growth and prevented tumor development. genetics_knock down_suppress hsa-mir-122 Hepatitis C Virus Infection 25848473 "miR-122 promotes HCV accumulation, inhibition of miR-122 has been shown as an effective therapy for the treatment of HCV infection in both chimpanzees and humans." genetics_knock down_suppress hsa-mir-221 Rheumatoid Arthritis 25891943 Downregulation of miR-221 significantly suppressed the expression of pro-inflammatory cytokines and the chemokine genetics_knock down_suppress hsa-mir-31 Myocardial Infarction 25925791 miR-31 downregulation alleviated myocardial infarct size in vivo. genetics_knock down_suppress hsa-mir-208a Myocardial Infarction 25936493 Overexpression of antagomir-208a and pretreatment with atorvastatin and valsartan in the AMI group significantly decreased the area of myocardial fibrosis induced by infarction. genetics_knock down_suppress hsa-mir-21 Glioblastoma 25991676 Both MPS1 and miR-21 depletion suppressed GBM cell proliferation genetics_knock down_suppress hsa-mir-195 Diabetic Cardiomyopathies 25994075 Therapeutic silencing of miR-195 reduces myocardial hypertrophy and improves coronary blood flow and myocardial function in diabetes genetics_knock down_suppress hsa-mir-21 Colorectal Carcinoma 25994220 "miR-21-knockout mice showed reduced expression of proinflammatory and procarcinogenic cytokines (interleukin (IL) 6, IL-23, IL-17A and IL-21) and a decrease in the size and number of tumours compared with the control mouse group." genetics_knock down_suppress hsa-let-7 Neoplasms [unspecific] 26033159 "we found that expression of DICER1 hotspot mutants promoted cell proliferation, whereas wild-type (WT) DICER1 inhibited cell proliferation. Furthermore, targets of let-7 family miRNAs are enriched among the up-regulated genes, suggesting that loss of let-7 may be impacting downstream pathways. Our results reveal that DICER1 hotspot mutations are implicated in common malignancies and may constitute a unique oncogenic pathway." genetics_knock down_suppress hsa-mir-34a Myocardial Infarction 26082557 locked nucleic acid-based anti-miR-34a treatment diminished post-MI miR-34a upregulation in adult hearts and significantly improved post-MI remodeling. genetics_knock down_suppress hsa-mir-150 Myocardial Infarction 26109086 MicroRNA-150 deletion in mice protects kidney from myocardial infarction-induced acute kidney injury. genetics_knock down_suppress hsa-mir-214 Liver Fibrosis 26122702 Pdgf-c Tg mice treated with LNA-antimiR-214 showed a marked reduction in fibrosis and tumor incidence compared with saline or LNA-miR-control-injected control mice. genetics_knock down_suppress hsa-mir-17 Graft-Versus-Host Disease 26138686 "Furthermore, we evaluated a translational approach and found that systemic administration of antagomir to block miR-17 or miR-19b in this cluster significantly inhibited alloreactive T-cell expansion and interferon-γ (IFNγ) production, and prolonged" genetics_knock down_suppress hsa-mir-19b Graft-Versus-Host Disease 26138686 systemic administration of antagomir to block miR-17 or miR-19b in this cluster significantly inhibited alloreactive T-cell expansion and interferon-γ (IFNγ) production genetics_knock down_suppress hsa-mir-372 "Adenocarcinoma, Gastric" 26151747 "Subcutaneously delivered LNAs reduce tumor growth of AGS xenografts in mice, upon formation of a stable, specific heteroduplex with the targeted miR-372 and -373 and LATS2 upregulation." genetics_knock down_suppress hsa-mir-150 Liver Injury 26196694 miR-150 deficiency prevents Fas-induced hepatocyte apoptosis and liver injury through regulation of the Akt pathway. genetics_knock down_suppress hsa-mir-181a Ischemic Diseases [unspecific] 26283227 "Delivery of anti-miR-181a, which neutralizes endogenous miR-181a, significantly attenuated H2O2-induced decrease of HKII expression and disruption of mitochondrial membrane potential, improving the survival of MSCs exposed to H2O2." genetics_knock down_suppress hsa-mir-31 "Squamous Cell Carcinoma, Esophageal" 26286729 anti-miR-31 reduced miR-31 overexpression (P = .002) and suppressed the esophageal preneoplasia in Zn-deficient rats. genetics_knock down_suppress hsa-mir-214 "Adenocarcinoma, Lung" 26299367 "downregulation of miR-214 expression in CSLCs resulted in a significant decrease in spheroid formation and the expression of the stem-cell markers Nanog, Oct-4, and Sox-2." genetics_knock down_suppress hsa-mir-21 "Fatty Liver, Non-Alcoholic" 26338827 "MicroRNA-21 inhibition or suppression decreases liver injury, inflammation and fibrosis" genetics_knock down_suppress hsa-mir-155 Stroke 26354913 In Vivo Inhibition of miR-155 Promotes Recovery after Experimental Mouse Stroke. genetics_knock down_suppress hsa-mir-20a "Carcinoma, Lung, Non-Small-Cell" 26356817 Stable knock down of miR-20a increases TβRII expression and inhibits tumorigenicity of lung cancer cells in vivo. genetics_knock down_suppress hsa-mir-205 Neoplasms [unspecific] 26446417 "When HEC-50B cells and HEC-1-A cells were treated with anti-miR-205 inhibitor, the migration and invasion were decreased as compared with the negative control." genetics_knock down_suppress hsa-mir-222 Pancreatic Neoplasms 26535064 "we co-transfected miR-222 inhibitor and p57 si-RNA into Capan-2 cells, and found that proliferation-suppressing effects of miR-222 inhibitor on Capan-2 cells could be partially reversed by silencing p57." genetics_knock down_suppress hsa-mir-192 "Adenocarcinoma, Lung" 26550150 MiR-192 inhibitor treated tumor exhibits sensitivity to cisplatin and gemcitabine therapy. genetics_knock down_suppress hsa-mir-503 "Carcinoma, Esophageal" 26580839 The specific inhibition of miR-503 expression remarkably suppressed proliferation and invasion of tumor cells. genetics_knock down_suppress hsa-mir-96 Bladder Neoplasms 26582573 the inhibition of miR-96 expression remarkably decreased cell proliferation and promoted cell apoptosis of BC cell lines genetics_knock down_suppress hsa-mir-155 Acute Myocardial Infarction 26589288 "We reveal that in vivo, miR-155 knockout improves left ventricular function, reduces infarct size, and attenuates collagen deposition, whereas overexpression of miR-155 produces the opposite effects." genetics_knock down_suppress hsa-mir-106b "Carcinoma, Renal Cell" 26648244 Downregulation of miR-106b with a synthesized inhibitor suppressed cell migration and proliferation and induced renal cancer cell apoptosis genetics_knock down_suppress hsa-mir-208a Myocardial Infarction 26688617 "Therapeutic inhibition of miR-208a decreased cardiac fibrosis, hypertrophy, and apoptosis and significantly improved cardiac function 28 days after MI." genetics_knock down_suppress hsa-mir-210 Nervous System Diseases [unspecific] 26708520 "Application of miR-210 inhibitor efficiently downregulated endogenous miR-210, protected apoptosis and neurite retraction in bupivacaine damaged DRG neurons." genetics_knock down_suppress hsa-mir-184 "Adenocarcinoma, Pancreatic Ductal" 26722418 "The transfection of inhibitor effectively suppressed the expression of miR-184, and further inhibited both cell proliferation and invasion abilities, in addition to the up-regulation of pro-apoptotic protein caspase 3 expression." genetics_knock down_suppress hsa-mir-630 Ovarian Neoplasms 26725326 Treatment with the combination of anti-miR-630 and anti-vascular endothelial growth factor antibody in mice resulted in rescue of Dicer expression and significantly decreased tumor growth and metastasis. genetics_knock down_suppress hsa-mir-15b Colorectal Carcinoma 26743779 "Inhibition of miR-15b activity by adenovirus carrying antimiR-15b sequence significantly increased MTSS1 and Klotho protein expression and subsequently decreased colony formation ability, invasion, and migration of HCT116 cells in vitro and liver metastasis of HCT116 tumors in vivo." genetics_knock down_suppress hsa-mir-193 Gastric Neoplasms 26753960 "In AGS and MKN-45 cells, miR-193-3p downregulation reduced cancer proliferation, migration and 5-FU chemoresistance in vitro, and tumorigenicity in vivo." genetics_knock down_suppress hsa-mir-126 Myocardial Infarction 26782549 miR-126 is down-regulated in myocardial ischemia-reperfusion injury and that the inhibition of miR-126 may protect against myocardial cell apoptosis caused by ischemia-reperfusion. genetics_knock down_suppress hsa-mir-223 Encephalomyelitis 26783338 We demonstrate that miR-223-knockout mice display significantly reduced active and adoptive-transfer experimental autoimmune encephalomyelitis genetics_knock down_suppress hsa-mir-125b Amyotrophic Lateral Sclerosis 26794445 "by restoring A20 levels, miR-125b inhibition then sustains motor neuron survival." genetics_knock down_suppress hsa-mir-210 Myocardial Infarction 26807177 Inhibition of miR-210 expression improved the survival and cardiac function of MI mice. genetics_knock down_suppress hsa-mir-130b "Carcinoma, Hepatocellular" 26861561 knockdown or overexpression of miR-130b inhibited and promoted proliferation and metastasis of HCC cells genetics_knock down_suppress hsa-mir-21 Myocardial Ischemic-Reperfusion Injury 26862785 recombinant HMGB1-box treatment protects against I/R injury and the mechanisms may involve inhibition of miR-21 expression. genetics_knock down_suppress hsa-mir-183 Pancreatic Adenocarcinoma 26870180 miR-183 knockdown decreased cell growth and motility in pancreatic cancer cells and significantly increased the expression of SOCS-6. genetics_knock down_suppress hsa-mir-146b "Carcinoma, Thyroid, Papillary" 26883911 miR-146b-5p positively regulates migration and invasion of thyroid normal and tumor follicular cells genetics_knock down_suppress hsa-mir-222 Neoplasms [unspecific] 26909602 "Anti-miR-222 inhibitor treatment decreased cell proliferation, migration, tube formation, and induced apoptosis." genetics_knock down_suppress hsa-mir-199a Pancreatic Neoplasms 26918939 "Inhibition of miR-199a/-214 using hairpin inhibitors significantly inhibited TGFβ-induced differentiation markers (e.g. α-SMA, collagen, PDGFβR), migration and proliferation." genetics_knock down_suppress hsa-mir-34a Cholangiocarcinoma 26923637 "The inhibition of miR-34a decreased proliferation, migration and invasion in cholangiocarcinoma cells." genetics_knock down_suppress hsa-mir-125b Melanoma 26968260 inhibition of miR-125b reduces migratory and invasive potentials without affecting cell proliferation in vitro. genetics_knock down_suppress hsa-mir-21 Ischemia-Reperfusion Injury 27030384 "With downregulation of miR-21, the protection of delayed IPC was attenuated and PHD2 protein was increased." genetics_knock down_suppress hsa-mir-223 Multiple Sclerosis 27083389 "miR223 promotes EAE, probably through enhancing DC activation and subsequently the differentiation of naive T cells toward Th1 and Th17 effector cells." genetics_knock down_suppress hsa-mir-25 Choriocarcinoma 27120728 Inhibition of miR-25 by its sponge in AGS cells resulted in suppressed cell viability (P<0.01) and promoted cell apoptosis (P<0.01) genetics_knock down_suppress hsa-mir-192 Liver Injury 27129188 "Functional experiments confirmed a protective effect of down-regulation of miR-192-5p in hepatocytes, suggesting a role of miR-192-5p in limiting liver injury." genetics_knock down_suppress hsa-mir-23b "Carcinoma, Nasopharyngeal" 27150436 "inhibition of miRâ€?3b could significantly suppress NPC cell proliferation, migration and invasion." genetics_knock down_suppress hsa-mir-128 Myocardial Ischemic-Reperfusion Injury 27150726 miRâ€?28 antagomirs significantly reduced apoptosis in hearts subjected to I/R injury genetics_knock down_suppress hsa-mir-125b "Leukemia, Myeloid, Chronic" 27158338 inhibition of miR-125b decreased the proliferation rates and promoted apoptosis with cell cycle arrest at the G0/G1 phase in both K562 and NB-4 cells genetics_knock down_suppress hsa-mir-451 "Leukemia, Myeloid, Chronic" 27158338 inhibition of miR-125b decreased the proliferation rates and promoted apoptosis with cell cycle arrest at the G0/G1 phase in both K562 and NB-4 cells genetics_knock down_suppress hsa-mir-224 Cerebral Ischemia 27165196 miR-224 inhibitor reduced neuronal cell apoptosis genetics_knock down_suppress hsa-mir-544a Colorectal Carcinoma 27165435 miR-544a inhibitor and/or HOXA10 overexpression reduced lung metastases in HCT116 xenografts. genetics_knock down_suppress hsa-mir-592 Colorectal Carcinoma 27167185 "miR-592 inhibitor exhibited a significant reduction of migration, proliferation, and clonogenicity in CRC cells." genetics_knock down_suppress hsa-mir-21 Esophageal Neoplasms 27188433 "the proliferation, migration, and invasion of TE11 cells were less active in Inhibition-miR21 group." genetics_knock down_suppress hsa-mir-138 Intervertebral Disc Degeneration 27207584 "inhibition of miR-138-5p downregulated PTEN protein expression and promoted activation of PI3K/AKT, and knockdown of either SIRT1 or the PI3K/Akt inhibitor (LY294002) abolished the effect of miR-138-5p on NP cell apoptosis." genetics_knock down_suppress hsa-mir-27b "Carcinoma, Lung, Non-Small-Cell" 27221512 introduction of miRâ€?7b inhibitors significantly induced apoptosis and inhibited the proliferation of A549 cells. genetics_knock down_suppress hsa-mir-21 Liver Cirrhosis 27226339 Ad-TuD-21 administered to liver fibrosis rats could remarkably suppress profibrotic gene expression genetics_knock down_suppress hsa-mir-455 "Squamous Cell Carcinoma, Oral" 27235675 MiR-455-5p knockdown reduced both the anchorage-independent growth and the proliferative ability of oral cancer cells genetics_knock down_suppress hsa-mir-454 "Carcinoma, Lung, Non-Small-Cell" 27261580 "Down-regulation of miR-454 could significantly reduce NSCLC cell proliferation, enhance cell apoptosis, and impair cell invasion and migration in vitro, while up-regulation of miR-454 showed opposite effects." genetics_knock down_suppress hsa-mir-93 Cervical Neoplasms 27279231 Enforced miR-93 knockdown or RAB11FIP1 overexpression suppressed proliferation and promoted apoptosis genetics_knock down_suppress hsa-mir-206 Mycobacterium tuberculosis Infection 27291149 Inhibition of miR-206 markedly suppressed inflammatory cytokine secretion genetics_knock down_suppress hsa-mir-155 Graft-Versus-Host Disease 27296836 miR-155-/- mice showed resistance to cardiac rejection along with weakened T-cell-mediated inflammation genetics_knock down_suppress hsa-mir-224 Gastric Neoplasms 27315344 "inhibition of miR-224 significantly reduced the expression of mTOR and improved caspase-9/3 expression while decreased cyclin D1/2 levels, attenuating gastric cancer cell proliferation." genetics_knock down_suppress hsa-mir-214 Breast Neoplasms 27328731 "Depleting miR-214 or elevating miR-148b blocked the dissemination of melanoma or breast cancer cells, an effect that could be accentuated by dual alteration." genetics_knock down_suppress hsa-mir-214 Melanoma 27328731 "Depleting miR-214 or elevating miR-148b blocked the dissemination of melanoma or breast cancer cells, an effect that could be accentuated by dual alteration." genetics_knock down_suppress hsa-mir-154 Glioblastoma 27338789 Knockdown of miR-154 remarkably suppressed proliferation and migration of CD133(+) GBM cells. genetics_knock down_suppress hsa-mir-24 "Squamous Cell Carcinoma, Tongue" 27350307 "Inhibition of miR-24 significantly suppressed the proliferation, migration and invasion of TSCC cells in vitro." genetics_knock down_suppress hsa-mir-21 Colorectal Adenocarcinoma 27364574 Locked nucleic acid anti-miR-21 inhibits cell growth and invasive behaviors of a colorectal adenocarcinoma cell line genetics_knock down_suppress hsa-mir-155 Acute Lung Injury 27371731 miR-155 gene inactivation protected mice from LPS-induced ALI genetics_knock down_suppress hsa-mir-181a "Carcinoma, Hepatocellular" 27384977 "Exogenous miR-181a expression in HepG2 cells reduced apoptosis, whereas inhibition of miR-181a in Hpe3B cells increased apoptosis." genetics_knock down_suppress hsa-mir-9 "Carcinoma, Breast, Triple Negative" 27402080 "miR-9 and miR-200 promoted and inhibited, respectively, the formation of vascular-like structures in vitro" genetics_knock down_suppress hsa-mir-23a Macular Degeneration 27411920 Inhibition of the H2O2-induced miR-23a by antagomiR protected the RPE cells from the oxidative stress-induced cell death. genetics_knock down_suppress hsa-mir-18a "Adenocarcinoma, Lung" 27412935 Downregulation of miR-18a or miR-328 can inhibit the invasion and migration abilities of A549 cells effectively. genetics_knock down_suppress hsa-mir-328 "Adenocarcinoma, Lung" 27412935 Downregulation of miR-18a or miR-328 can inhibit the invasion and migration abilities of A549 cells effectively. genetics_knock down_suppress hsa-mir-200a Breast Neoplasms 27433802 "We further showed that inhibition of miR-200a function, mimicking the effect of calorie restriction on this microRNA, inhibited proliferation in both rat (LA7) and human (MCF7) luminal mammary cancer cell lines." genetics_knock down_suppress hsa-mir-942 Kaposi Sarcoma 27440900 "Suppression of miR-942-5p relieved I¦ÊB¦Á expression and reduced Vpr inhibition of KSHV replication, while overexpression of miR-942-5p enhanced Vpr inhibition of KSHV replication." genetics_knock down_suppress hsa-mir-10b Endometrial Neoplasms 27447302 "The silence of miR-10b resulted in significantly enhanced cell apoptosis, and remarkably reduced cell proliferation, migration, and invasion (pâ€?â€?.05)." genetics_knock down_suppress hsa-mir-9 Prostate Neoplasms 27447934 "Inhibition of miR-9 resulted in reduced migratory and invasive potential of the M12 cell line, and reduced tumour growth and metastases in male athymic nude mice." genetics_knock down_suppress hsa-mir-21 Asthma 27448447 "Treatment with Ant-21, or the pan-PI3K inhibitor LY294002, reduced PI3K activity and restored HDAC2 levels. This led to suppression of airway hyperresponsiveness and restored steroid sensitivity to allergic airway disease." genetics_knock down_suppress hsa-mir-106b Pituitary Neoplasms 27465551 "Down-regulation of miR-106b or up-regulation of PTEN could suppress cell proliferation and invasion of AtT-20 cells, and PTEN expression plasmid could partially simulate the function of miR-106b." genetics_knock down_suppress hsa-mir-155 "Carcinoma, Cervical" 27470551 "Moreover, knockdown of miR-155 was demonstrated to inhibit cell proliferation, migration, and invasion in vitro." genetics_knock down_suppress hsa-mir-210 Epilepsy 27471387 Our data showed that morphological changes of hippocampal neurons and apoptosis triggered by epilepsy were mitigated by miR-210 inhibition. genetics_knock down_suppress hsa-mir-182 "Carcinoma, Breast, Triple Negative" 27476169 Knockdown of miR-182 promotes apoptosis via regulating RIP1 deubiquitination in TNF-α-treated triple-negative breast cancer cells. genetics_knock down_suppress hsa-mir-137 Vascular Injuries 27497953 "Down-regulation of miR-137 ameliorates HG-induced injury in HUVECs by overexpression of AMPKα1, leading to increasing cellular reductive reactions and decreasing oxidative stress." genetics_knock down_suppress hsa-mir-17 Lymphoma 27498867 "Loss of miR-17/92 in Myc(+) tumor cells leads to a global decrease in tumor cell metabolism, affecting both glycolytic and mitochondrial metabolism, whereas increased miR-17/92 expression is sufficient to drive increased nutrient usage by tumor cells." genetics_knock down_suppress hsa-mir-126 "Carcinoma, Hepatocellular" 27499630 Inhibition of miR-126 expression increased Spred1 expression and decreased vascular endothelial growth factor expression (P<0.01). genetics_knock down_suppress hsa-mir-346 "Carcinoma, Nasopharyngeal" 27501413 Inhibition of miR-346 significantly attenuated the migration and invasion of NPC cells. genetics_knock down_suppress hsa-mir-106a "Carcinoma, Ovarian" 27510094 Downregulation of the expression of miR-106a inhibited cell growth and metastasis of ovarian cancer cells. genetics_knock down_suppress hsa-mir-24 "Squamous Cell Carcinoma, Head and Neck" 27513190 "Inhibition of miR-24-3p reduced cell proliferation, colony formation efficiency and reversed chemoresistance in HNSCC cells." genetics_knock down_suppress hsa-mir-21 Osteosarcoma 27513462 microRNA-21 inhibition slowed proliferation and exogenously expressed microRNA-21 promoted this process. genetics_knock down_suppress hsa-mir-106b "Carcinoma, Breast" 27519168 "down-regulation of miR-106b increased the expression of FUT6 and resulted in an obvious decrease of cell migration, invasion, and proliferation in MDA-MB-231 cells." genetics_knock down_suppress hsa-mir-127 Obesity 27532680 "On the other hand, locked nucleic acid inhibitor synthesized to target miR-127-5p significantly increased b-F1-ATPase translation efficiency in myotubes." genetics_knock down_suppress hsa-mir-21 Melanoma 27533779 "MiR-21 can promote the proliferation, migration, and inhibit the apoptosis of human melanoma A375 cells by inhibiting SPRY1, PDCD4, and PTEN via ERK/NF-kB signaling pathway." genetics_knock down_suppress hsa-mir-181a "Carcinoma, Cervical" 27534652 Inhibition of microRNA-181a may suppress proliferation and invasion and promote apoptosis of cervical cancer cells through the PTEN/Akt/FOXO1 pathway. genetics_knock down_suppress hsa-mir-21 Liver Cirrhosis 27775690 Knockout of microRNA-21 reduces biliary hyperplasia and liver fibrosis in cholestatic bile duct ligated mice. genetics_knock down_suppress hsa-mir-322 "Carcinoma, Breast" 28404630 miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy. genetics_knock down_suppress hsa-mir-424 "Carcinoma, Breast" 28404630 miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy. genetics_knock down_suppress hsa-mir-503 "Carcinoma, Breast" 28404630 miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy. genetics_knock down_suppress hsa-mir-27a Colorectal Carcinoma 28423356 Knockdown of miR-27a sensitizes colorectal cancer stem cells to TRAIL by promoting the formation of Apaf-1-caspase-9 complex. genetics_knock down_suppress hsa-mir-155 Infection [unspecific] 28804270 Knockdown of miR-155 protects microglia against LPS-induced inflammatory injury via targeting RACK1: a novel research for intracranial infection genetics_knock down_suppress hsa-mir-29a "Carcinoma, Breast" 29021023 Knockdown of microRNA-29a Changes the Expression of Heat Shock Proteins in Breast Carcinoma MCF-7 Cells. genetics_knock down_suppress hsa-mir-29a "Carcinoma, Breast" 29435304 Knockdown of microRNA-29a regulates the expression of apoptosis-related genes in MCF-7 breast carcinoma cells genetics_knock down_suppress hsa-mir-21 Neoplasms [unspecific] 29540832 miR-21 depletion in macrophages promotes tumoricidal polarization and enhances PD-1 immunotherapy genetics_knock down_suppress hsa-mir-146a Listeriosis 29587465 MicroRNA-146a Deficiency Protects against Listeria monocytogenes Infection by Modulating the Gut Microbiota genetics_knock down_suppress hsa-mir-21 Colitis 29608690 Loss of microRNA-21 Influences the Gut Microbiota Causing Reduced Susceptibility in a Murine Model of Colitis genetics_knock down_suppress hsa-mir-21 Alcoholic Hepatitis 29848019 Knockout of microRNA-21 attenuates alcoholic hepatitis through the VHL/NF-¦ÊB signaling pathway in hepatic stellate cells. genetics_knock down_suppress hsa-mir-1246 "Carcinoma, Cervical" 30078258 Lentivirus media miR-1246 knockdown inhibits tumor growth and promotes apoptosis of SiHa cells genetics_knock down_suppress hsa-mir-299 "Carcinoma, Hepatocellular" 30266288 Knockdown of miR-299-5p inhibits the progression of hepatocellular carcinoma by targeting SIAH1. genetics_overexpression_promote hsa-mir-17 Lymphoma 16940181 "Mir-17-5p, also known as Mir-91,is located on chromosome 13q31; this gene is amplified in childhoodlymphoma." genetics_overexpression_promote hsa-mir-17 Hematologic Neoplasms 17011485 The miR-17-92 cluster is amplified in hematopoietic malignancies. genetics_overexpression_promote hsa-mir-18a Hematologic Neoplasms 17011485 The miR-17-92 cluster is amplified in hematopoietic malignancies. genetics_overexpression_promote hsa-mir-19a Hematologic Neoplasms 17011485 The miR-17-92 cluster is amplified in hematopoietic malignancies. genetics_overexpression_promote hsa-mir-19b-1 Hematologic Neoplasms 17011485 The miR-17-92 cluster is amplified in hematopoietic malignancies. genetics_overexpression_promote hsa-mir-20a Hematologic Neoplasms 17011485 The miR-17-92 cluster is amplified in hematopoietic malignancies. genetics_overexpression_promote hsa-mir-17 Colon Neoplasms 17965831 "The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation." genetics_overexpression_promote hsa-mir-17 Lung Neoplasms 17965831 "The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation." genetics_overexpression_promote hsa-mir-18a Colon Neoplasms 17965831 "The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation." genetics_overexpression_promote hsa-mir-18a Lung Neoplasms 17965831 "The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation." genetics_overexpression_promote hsa-mir-19a Colon Neoplasms 17965831 "The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation." genetics_overexpression_promote hsa-mir-19a Lung Neoplasms 17965831 "The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation." genetics_overexpression_promote hsa-mir-19b-1 Colon Neoplasms 17965831 "The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation." genetics_overexpression_promote hsa-mir-19b-1 Lung Neoplasms 17965831 "The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation." genetics_overexpression_promote hsa-mir-20a Colon Neoplasms 17965831 "The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation." genetics_overexpression_promote hsa-mir-20a Lung Neoplasms 17965831 "The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation." genetics_overexpression_promote hsa-mir-92a-1 Colon Neoplasms 17965831 "The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation." genetics_overexpression_promote hsa-mir-92a-1 Lung Neoplasms 17965831 "The miRNA cluster miR-17-92 is located at 13q31.3 and has been associated with several types of cancer, including colorectal cancer and lung cancer, and is thought to be a potential oncogene [86, 87] that enhances cell proliferation." genetics_overexpression_promote hsa-let-7g "Carcinoma, Lung, Non-Small-Cell" 18308936 we observed significant growth reduction of both murine and human non-small cell lung tumors when overexpression of let-7g was induced from lentiviral vectors genetics_overexpression_promote hsa-mir-184 Squamous Cell Carcinoma 18451220 "Overexpression of miR-184 might play an oncogenic role in the antiapoptotic and proliferative processes of tongue SCC. In addition, plasma miR-184 levels were associated with the presence of primary tumor. " genetics_overexpression_promote hsa-mir-221 Prostate Neoplasms 19107213 miR-221: The inhibition of the highly expressed miR-221 and miR-222 impairs the growth of prostate carcinoma xenografts in mice genetics_overexpression_promote hsa-mir-222 Prostate Neoplasms 19107213 miR-222: The inhibition of the highly expressed miR-221 and miR-222 impairs the growth of prostate carcinoma xenografts in mice genetics_overexpression_promote hsa-mir-31 Leiomyosarcoma 19602040 overexpression; leads to HMGA2 overexpression; Disrupting the control of HMGA2 and let-7 pairs promotes ULMS cell growth in vitro. genetics_overexpression_promote hsa-mir-125a Ovarian Neoplasms 19881956 Overexpression of miR-125a induces conversion of highly invasive ovarian cancer cells genetics_overexpression_promote hsa-mir-26a Glioblastoma 20080666 "Overexpression of miR-26a in PTEN-competent and PTEN-deficient glioblastoma cells promoted tumor growth in vivo, and it further increased growth in cells overexpressing CDK4 or CENTG1." genetics_overexpression_promote hsa-mir-17 Neoplasms [unspecific] 20439436 mir-17:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted genetics_overexpression_promote hsa-mir-18a Neoplasms [unspecific] 20439436 mir-18a:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted genetics_overexpression_promote hsa-mir-19a Neoplasms [unspecific] 20439436 mir-19a:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted genetics_overexpression_promote hsa-mir-19b-1 Neoplasms [unspecific] 20439436 mir-19b:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted genetics_overexpression_promote hsa-mir-19b-2 Neoplasms [unspecific] 20439436 mir-19b:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted genetics_overexpression_promote hsa-mir-92a-1 Neoplasms [unspecific] 20439436 mir-92a:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted genetics_overexpression_promote hsa-mir-92a-2 Neoplasms [unspecific] 20439436 mir-92a:We correctly identified hsa-miR-17/92 family as amplified and the hsa-miR-143/145 cluster as deleted genetics_overexpression_promote hsa-mir-125b Leukemia 21118985 "Thus, we show that overexpression of miR-125b is sufficient both to shorten the latency of BCR-ABL-induced leukemia and to independently induce leukemia in a mouse model." genetics_overexpression_promote hsa-mir-18a Urinary Bladder Cancer 21388952 Specific deletion of p53 in urothelial cells is associated with specific overexpression of miR-18a and miR-19a and down-regulation of miR-107. genetics_overexpression_promote hsa-mir-19a Urinary Bladder Cancer 21388952 Specific deletion of p53 in urothelial cells is associated with specific overexpression of miR-18a and miR-19a and down-regulation of miR-107. genetics_overexpression_promote hsa-mir-155 Hepatitis C Virus Infection 21750860 Coordinated increase of miRNA-155 and miRNA-196b expression correlates with the detection of the antigenomic strand of hepatitis C virus in peripheral blood mononuclear cells. genetics_overexpression_promote hsa-mir-196b Hepatitis C Virus Infection 21750860 Coordinated increase of miRNA-155 and miRNA-196b expression correlates with the detection of the antigenomic strand of hepatitis C virus in peripheral blood mononuclear cells. genetics_overexpression_promote hsa-mir-125b-2 Glioblastoma 21879257 miR-125b-2 overexpression might confer glioblastoma stem cells resistance to TMZ. genetics_overexpression_promote hsa-mir-21 Breast Neoplasms 21917003 High expression of miR-21 in tumor stroma correlates with increased cancer cell proliferation in human breast cancer. genetics_overexpression_promote hsa-mir-17 "Lymphoma, Burkitt" 21981616 The minimum common amplified region on 13q was at 13q31 and included the MIR17HG (MIR17-92) locus. Samples with this gain had higher levels of MIR17 RNA and showed a tendency for early relapse. genetics_overexpression_promote hsa-mir-18a "Lymphoma, Burkitt" 21981616 The minimum common amplified region on 13q was at 13q31 and included the MIR17HG (MIR17-92) locus. Samples with this gain had higher levels of MIR17 RNA and showed a tendency for early relapse. genetics_overexpression_promote hsa-mir-19a "Lymphoma, Burkitt" 21981616 The minimum common amplified region on 13q was at 13q31 and included the MIR17HG (MIR17-92) locus. Samples with this gain had higher levels of MIR17 RNA and showed a tendency for early relapse. genetics_overexpression_promote hsa-mir-19b-1 "Lymphoma, Burkitt" 21981616 The minimum common amplified region on 13q was at 13q31 and included the MIR17HG (MIR17-92) locus. Samples with this gain had higher levels of MIR17 RNA and showed a tendency for early relapse. genetics_overexpression_promote hsa-mir-20a "Lymphoma, Burkitt" 21981616 The minimum common amplified region on 13q was at 13q31 and included the MIR17HG (MIR17-92) locus. Samples with this gain had higher levels of MIR17 RNA and showed a tendency for early relapse. genetics_overexpression_promote hsa-mir-92a-1 "Lymphoma, Burkitt" 21981616 The minimum common amplified region on 13q was at 13q31 and included the MIR17HG (MIR17-92) locus. Samples with this gain had higher levels of MIR17 RNA and showed a tendency for early relapse. genetics_overexpression_promote hsa-mir-10b Pancreatic Neoplasms 22018284 "MicroRNA-10b is overexpressed in pancreatic cancer, promotes its invasiveness, and correlates with a poor prognosis." genetics_overexpression_promote hsa-mir-17 Colon Neoplasms 22065543 "MiR-17-92 cluster and its paralogs were significantly overexpressed in colon tumor. No significant associations were found between the deregulation of certain miRNAs and the clinical and pathologic characteristics observed in patients. Kaplan-Meier curves demonstrated significantly reduced overall survival in patients expressing high levels of miR-17. In multivariate Cox models, miR-17 overexpression (HR 2.67; P=0.007) and TNM staging (HR 8.87; P=0.002) were significantly associated with a risk of death." genetics_overexpression_promote hsa-mir-18a Colon Neoplasms 22065543 "MiR-17-92 cluster and its paralogs were significantly overexpressed in colon tumor. No significant associations were found between the deregulation of certain miRNAs and the clinical and pathologic characteristics observed in patients. Kaplan-Meier curves demonstrated significantly reduced overall survival in patients expressing high levels of miR-17. In multivariate Cox models, miR-17 overexpression (HR 2.67; P=0.007) and TNM staging (HR 8.87; P=0.002) were significantly associated with a risk of death." genetics_overexpression_promote hsa-mir-19a Colon Neoplasms 22065543 "MiR-17-92 cluster and its paralogs were significantly overexpressed in colon tumor. No significant associations were found between the deregulation of certain miRNAs and the clinical and pathologic characteristics observed in patients. Kaplan-Meier curves demonstrated significantly reduced overall survival in patients expressing high levels of miR-17. In multivariate Cox models, miR-17 overexpression (HR 2.67; P=0.007) and TNM staging (HR 8.87; P=0.002) were significantly associated with a risk of death." genetics_overexpression_promote hsa-mir-19b-1 Colon Neoplasms 22065543 "MiR-17-92 cluster and its paralogs were significantly overexpressed in colon tumor. No significant associations were found between the deregulation of certain miRNAs and the clinical and pathologic characteristics observed in patients. Kaplan-Meier curves demonstrated significantly reduced overall survival in patients expressing high levels of miR-17. In multivariate Cox models, miR-17 overexpression (HR 2.67; P=0.007) and TNM staging (HR 8.87; P=0.002) were significantly associated with a risk of death." genetics_overexpression_promote hsa-mir-20a Colon Neoplasms 22065543 "MiR-17-92 cluster and its paralogs were significantly overexpressed in colon tumor. No significant associations were found between the deregulation of certain miRNAs and the clinical and pathologic characteristics observed in patients. Kaplan-Meier curves demonstrated significantly reduced overall survival in patients expressing high levels of miR-17. In multivariate Cox models, miR-17 overexpression (HR 2.67; P=0.007) and TNM staging (HR 8.87; P=0.002) were significantly associated with a risk of death." genetics_overexpression_promote hsa-mir-92a-1 Colon Neoplasms 22065543 "MiR-17-92 cluster and its paralogs were significantly overexpressed in colon tumor. No significant associations were found between the deregulation of certain miRNAs and the clinical and pathologic characteristics observed in patients. Kaplan-Meier curves demonstrated significantly reduced overall survival in patients expressing high levels of miR-17. In multivariate Cox models, miR-17 overexpression (HR 2.67; P=0.007) and TNM staging (HR 8.87; P=0.002) were significantly associated with a risk of death." genetics_overexpression_promote hsa-mir-125b-1 Rhinosinusitis 22071331 "Overexpression of miR-125b, a Novel Regulator of Innate Immunity, in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps." genetics_overexpression_promote hsa-mir-125b-2 Rhinosinusitis 22071331 "Overexpression of miR-125b, a Novel Regulator of Innate Immunity, in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps." genetics_overexpression_promote hsa-mir-155 "Carcinoma, Hepatocellular" 22071603 Up-regulation of microRNA-155 promotes cancer cell invasion and predicts poor survival of hepatocellular carcinoma following liver transplantation. genetics_overexpression_promote hsa-mir-223 "Squamous Cell Carcinoma, Esophageal" 22108521 Overexpression of microRNA-223 regulates the ubiquitin ligase FBXW7 in oesophageal squamous cell carcinoma. genetics_overexpression_promote hsa-mir-124-1 Neuroblastoma 22123030 "Ectopic overexpression of miR-124 resulted in the downregulation of CDK6, decreased cellular proliferation, and induced cellular morphological changes." genetics_overexpression_promote hsa-mir-124-2 Neuroblastoma 22123030 "Ectopic overexpression of miR-124 resulted in the downregulation of CDK6, decreased cellular proliferation, and induced cellular morphological changes." genetics_overexpression_promote hsa-mir-124-3 Neuroblastoma 22123030 "Ectopic overexpression of miR-124 resulted in the downregulation of CDK6, decreased cellular proliferation, and induced cellular morphological changes." genetics_overexpression_promote hsa-mir-122 "Carcinoma, Hepatocellular" 22140464 "miR-122 expression is highly elevated in quiescent human primary hepatocytes (hPHs) but lost or attenuated in hESCs and HCCs, while an opposing expression pattern is observed for Pkm2. Depleting hESCs and HCCs of Pkm2, or overexpressing miR-122, leads to a common deficiency in self-renewal and proliferation." genetics_overexpression_promote hsa-mir-223 "Leukemia, Lymphocytic, Chronic, B-Cell" 22145958 microRNA-223 expression is uniformly down-regulated in B cell lymphoproliferative disorders and is associated with poor survival in chronic lymphocytic leukemia patients. genetics_overexpression_promote hsa-mir-200a Prostate Neoplasms 22161972 "miR-200a overexpression reduced prostate cancer cell growth and may have potential, in combination with other markers, in stratifying prostate cancer patients for more intensive monitoring and therapy." genetics_overexpression_promote hsa-mir-28 Colorectal Carcinoma 22240480 "miR-28-5p altered expression of CCND1 and HOXB3, whereas miR-28-3p bound NM23-H1. Overexpression of miR-28-5p reduced CRC cell proliferation, migration, and invasion in vitro, whereas miR-28-3p increased CRC cell migration and invasion in vitro." genetics_overexpression_promote hsa-mir-182 Ovarian Neoplasms 22322863 "miR-182 overexpression resulted in increased tumor transformation in vitro, and enhanced tumor invasiveness in vitro and metastasis in vivo. The oncogenic properties of miR-182 in ovarian cancer were mediated in part by its impaired repair of DNA double-strand breaks and negative regulation of breast cancer 1 (BRCA1) and metastasis suppressor 1 (MTSS1) expressions as well as its positive regulation of oncogene high-mobility group AT-hook 2 (HMGA2)." genetics_overexpression_promote hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 22335905 Overexpression of miR-21 promotes proliferation and reduces apoptosis in non-small cell lung cancer]. genetics_overexpression_promote hsa-mir-34a Myocardial Infarction 22403243 "IGF-1 significantly inhibited H(2)O(2)-induced miR-34a expression, and miR-34a overexpression abolished the anti-apoptotic effect of IGF-1." genetics_overexpression_promote hsa-mir-17 Leukemia 22451425 "In both murine and human leukemias, p53 inactivation contributed to the selective overexpression of oncogenic miR-92a and miR-19a, and down-regulation of tumor-suppressive miR-17." genetics_overexpression_promote hsa-mir-19a Acute Erythroid Leukemia 22451425 "overexpression of individual miRNAs from this locus, miR-19a or miR-92a, results in B-cell hyperplasia and erythroleukemia, respectively." genetics_overexpression_promote hsa-mir-92a Acute Erythroid Leukemia 22451425 "overexpression of individual miRNAs from this locus, miR-19a or miR-92a, results in B-cell hyperplasia and erythroleukemia, respectively." genetics_overexpression_promote hsa-mir-130a Ovarian Neoplasms 22455133 The over expression of miR-130a is associated with cisplatin resistance of ovarian cancer. Inhibiting miR-130a expression may help reverse the cisplatin resistance of ovarian cancer. genetics_overexpression_promote hsa-mir-21 Breast Neoplasms 22547075 DNA damage induces NF-kB-dependent microRNA-21 upregulation and promotes breast cancer cell invasion. genetics_overexpression_promote hsa-mir-125b "Leukemia, Myeloid, Acute" 22689670 "We previously described a t(2;11)(p21;q23) chromosomal translocation found in patients with myelodysplasia or acute myeloid leukemia that leads to over-expression of the microRNA miR-125b, and we showed that transplantation of mice with murine stem/progenitor cells overexpressing miR-125b is able to induce leukemia." genetics_overexpression_promote hsa-mir-615 "Carcinoma, Hepatocellular" 22819824 miR-615-5p is restrictedly expressed in cirrhotic and cancerous liver tissues and its overexpression alleviates the tumorigenic effects in hepatocellular carcinoma. genetics_overexpression_promote hsa-mir-221 Thyroid Neoplasms 22855362 Overexpression of miR-221 is associated with aggressive clinicopathologic characteristics and the BRAF mutation in papillary thyroid carcinomas. genetics_overexpression_promote hsa-mir-132 Heart Failure 23011132 "MiR-212/132 null mice are protected from pressure-overload-induced heart failure, whereas cardiomyocyte-specific overexpression of the miR-212/132 family leads to pathological cardiac hypertrophy, heart failure and death in mice." genetics_overexpression_promote hsa-mir-212 Heart Failure 23011132 "MiR-212/132 null mice are protected from pressure-overload-induced heart failure, whereas cardiomyocyte-specific overexpression of the miR-212/132 family leads to pathological cardiac hypertrophy, heart failure and death in mice." genetics_overexpression_promote hsa-mir-221 Inflammation 23023232 "The overexpression of oncogenic miR-221 and miR-222 caused by HMGB1 is associated with an increase in malignancy scores, namely cell growth and motility." genetics_overexpression_promote hsa-mir-222 "Carcinoma, Thyroid, Papillary" 23023232 "The overexpression of oncogenic miR-221 and miR-222 caused by HMGB1 is associated with an increase in malignancy scores, namely cell growth and motility." genetics_overexpression_promote hsa-mir-17 Gastric Neoplasms 23333058 "Overexpression of miR-17-5p/20a promoted gastric cancer cell cycle progression and inhibited cell apoptosis, whereas knockdown of miR-17-5p/20a resulted in cell cycle arrest and increased apoptosis." genetics_overexpression_promote hsa-mir-20a Gastric Neoplasms 23333058 "Overexpression of miR-17-5p/20a promoted gastric cancer cell cycle progression and inhibited cell apoptosis, whereas knockdown of miR-17-5p/20a resulted in cell cycle arrest and increased apoptosis." genetics_overexpression_promote hsa-mir-100 "Carcinoma, Renal Cell" 23378187 miR-100 overexpression strongly associates with advanced tumor progression and unfavorable clinical outcome of patients with RCC genetics_overexpression_promote hsa-mir-106b "Carcinoma, Hepatocellular" 23483935 Over-Expression of miR-106b Promotes Cell Migration and Metastasis in Hepatocellular Carcinoma by Activating Epithelial-Mesenchymal Transition Process genetics_overexpression_promote hsa-mir-449a "Adenocarcinoma, Lung" 23614048 "Overexpression of miR-449a in CL1-0 cells effectively increased irradiation-induced DNA damage and apoptosis,altered the cell cycle distribution and eventually led to sensitization of CL1-0 to irradiation." genetics_overexpression_promote hsa-mir-1 Myocardial Infarction 23615185 Overexpression of MicroRNA-1 improves the efficacy of mesenchymal stem cell transplantation after myocardial infarction. genetics_overexpression_promote hsa-mir-146a Sepsis 23638011 Overexpression of miR-146a induces a state analogous to tolerance in BLP-stimulated cells and therefore may represent a future target for exogenous modulation of tolerance during microbial infection and sepsis. genetics_overexpression_promote hsa-mir-9 Leukemia 23798388 miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia. genetics_overexpression_promote hsa-mir-146b Inflammation 23813877 MicroRNA-146b improves intestinal injury in mouse colitis by activating nuclear factor-¦ÊB and improving epithelial barrier function. genetics_overexpression_promote hsa-mir-22 Heart Failure 24086656 microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription. genetics_overexpression_promote hsa-mir-449a Retinoblastoma 24120948 We are the first to confirm an inhibitory effect of miR-449a and -449b in retinoblastoma by demonstrating significantly impaired proliferation and increased apoptosis of tumor cells when these miRNAs are overexpressed. genetics_overexpression_promote hsa-mir-32 Colorectal Carcinoma 24123284 "MiR-32 overexpression was correlated with specific CRC clinicopathological features and may be a marker of poor prognosis in CRC patients. MiR-32 and PTEN expression were inversely correlated, and miR-32 may be associated with the development of CRC." genetics_overexpression_promote hsa-mir-17 Leukemia 24145403 "The miR-17?92 overexpression was driven by the E?-enhancer and Ig heavy-chain promoter, and a 3' GFP tag was added to the transgene to track the miR expression." genetics_overexpression_promote hsa-mir-18a "Leukemia, B-Cell" 24145403 "The miR-17?92 overexpression was driven by the E?-enhancer and Ig heavy-chain promoter, and a 3' GFP tag was added to the transgene to track the miR expression." genetics_overexpression_promote hsa-mir-19a "Leukemia, B-Cell" 24145403 "The miR-17?92 overexpression was driven by the E?-enhancer and Ig heavy-chain promoter, and a 3' GFP tag was added to the transgene to track the miR expression." genetics_overexpression_promote hsa-mir-19b "Leukemia, B-Cell" 24145403 "The miR-17?92 overexpression was driven by the E?-enhancer and Ig heavy-chain promoter, and a 3' GFP tag was added to the transgene to track the miR expression." genetics_overexpression_promote hsa-mir-92a "Leukemia, B-Cell" 24145403 "The miR-17?92 overexpression was driven by the E?-enhancer and Ig heavy-chain promoter, and a 3' GFP tag was added to the transgene to track the miR expression." genetics_overexpression_promote hsa-mir-21 Colorectal Carcinoma 24149370 "miR-21 is a key player in oncogenic EMT, its overexpression is controlled by the cooperation of genetic and epigenetic alterations, and its levels, along with ITG¦Â4 and PDCD4 expression, could be exploited as a prognostic tool for CRC metastasis." genetics_overexpression_promote hsa-mir-18a Toxic Epidermal Necrolysis 24184144 Our results indicated that downregulated BCL2L10 caused by miR-18a-5p overexpression mediates intrinsic keratinocyte apoptosis in patients with TEN. Serum miR-18a-5p levels can be a useful disease marker for drug eruptions. genetics_overexpression_promote hsa-let-7a Systemic Lupus Erythematosus 24240124 our results suggest that overexpression of let-7a may contribute to hyperplasia and the proinflammatory response in SLE. genetics_overexpression_promote hsa-mir-296 Prostate Neoplasms 24263102 "Interestingly, ectopic expression of miR-296-3p in P69 increases the tolerance to NK cells whereas knockdown of miR-296-3p in M12 reduces the resistance to NK cells, which both phenotypes can be rescued by re-expression or silencing of ICAM-1 in P69 and M12, respectively." genetics_overexpression_promote hsa-mir-9 Pulmonary Hypertension 24615545 "Knockdown of miR-9 followed by hypoxia exposure attenuated PASMCs proliferation and enhanced the expression of contractile genes in vascular smooth muscle cells (VSMCs), while overexpression of miR-9 in normoxia promoted a proliferative phenotype in PASMCs." genetics_overexpression_promote hsa-mir-210 Gastrointestinal Stromal Tumor 24623741 "Overexpression of miR-210 is associated with SDH-related pheochromocytomas, paragangliomas, and gastrointestinal stromal tumours." genetics_overexpression_promote hsa-mir-125a Myelodysplastic Syndromes 24690917 Overexpression of miR-125a in myelodysplastic syndrome CD34+ cells modulates NF-¦ÊB activation and enhances erythroid differentiation arrest. genetics_overexpression_promote hsa-mir-30c Heart Failure 24789369 Taken together these data indicate impaired mitochondrial function due to OXPHOS protein depletion as a potential cause for the observed dilated cardiomyopathic phenotype in miRNA-30c transgenic mice. genetics_overexpression_promote hsa-mir-429 Ovarian Neoplasms 24802724 Ectopic over-expression of miR-429 induces mesenchymal-to-epithelial transition (MET) and increased drug sensitivity in metastasizing ovarian cancer cells. genetics_overexpression_promote hsa-mir-30a Nasopharyngeal Neoplasms 24812123 "Furthermore, over-expression of miR-30a transfected with precursor increased the ability of metastasis and invasion of NPC tumor cells in vivo and in vitro." genetics_overexpression_promote hsa-mir-222 "Carcinoma, Hepatocellular" 24955159 "MiR-222 overexpression induced an enhancement of HepG2 cell proliferation in vitro, paralleling with an altered cell cycle progression via increased cell population in S phase." genetics_overexpression_promote hsa-mir-23b Breast Neoplasms 24966325 Ectopic expression of the miRNAs in the weakly metastatic mouse 4TO7 mammary tumor cell line had no effect on proliferation or morphology of tumor cells in vitro but was found to increase lung metastasis in a mouse model of breast cancer metastasis. genetics_overexpression_promote hsa-mir-24 Breast Neoplasms 24966325 Ectopic expression of the miRNAs in the weakly metastatic mouse 4TO7 mammary tumor cell line had no effect on proliferation or morphology of tumor cells in vitro but was found to increase lung metastasis in a mouse model of breast cancer metastasis. genetics_overexpression_promote hsa-mir-27b Breast Neoplasms 24966325 Ectopic expression of the miRNAs in the weakly metastatic mouse 4TO7 mammary tumor cell line had no effect on proliferation or morphology of tumor cells in vitro but was found to increase lung metastasis in a mouse model of breast cancer metastasis. genetics_overexpression_promote hsa-mir-9 Osteosarcoma 24969351 "The findings of our study suggest that increased miR-9 expression has a strong correlation with the aggressive progression of osteosarcoma and its overexpression is a statistically significant risk factor affecting overall survival, suggesting that increased miR-9 expression could be a valuable marker of tumor progression and for prognosis of osteosarcoma." genetics_overexpression_promote hsa-mir-17 Gastric Neoplasms 25047501 Overexpression of miR-17 in gastric cancer is correlated with proliferation-associated oncogene amplification. genetics_overexpression_promote hsa-mir-214 Cardiomegaly 25085702 Cardiac hypertrophy and dysfunction induced by overexpression of miR-214 in vivo. genetics_overexpression_promote hsa-mir-195 Heart Failure 25100012 Cardiac overexpression of miR-195 results in pathological cardiac growth and heart failure in transgenic mice. genetics_overexpression_promote hsa-mir-146a Breast Neoplasms 25123132 Overexpression of miR-146a in basal-like breast cancer cells confers enhanced tumorigenic potential in association with altered p53 status. genetics_overexpression_promote hsa-mir-21 Gastric Neoplasms 25230738 "This meta-analysis indicates that miR-21 detection has a prognostic value in patients with gastric cancer. In addition, overexpression of miR-21 is associated with worse tumor differentiation, lymph node metastasis, and TNM stage." genetics_overexpression_promote hsa-mir-196a Oral Neoplasms 25233933 "Functionally, miR-196 actively promoted cell migration and invasion without affecting cell growth." genetics_overexpression_promote hsa-mir-21 Neoplasms [unspecific] 25241894 Ectopic expression of miR-21 and miR-29a promotes angiogenesis and tumor cell proliferation genetics_overexpression_promote hsa-mir-223 Colorectal Carcinoma 25270282 Overexpression of miR-223 correlates with tumor metastasis and poor prognosis in patients with colorectal cancer. genetics_overexpression_promote hsa-mir-410 Colorectal Carcinoma 25272045 MiR-410 is overexpressed in liver and colorectal tumors and enhances tumor cell growth by silencing FHL1 via a direct/indirect mechanism. genetics_overexpression_promote hsa-mir-374a Neoplasms [unspecific] 25299640 The miR-545/374a cluster encoded in the Ftx lncRNA is overexpressed in HBV-related hepatocellular carcinoma and promotes tumorigenesis and tumor progression. genetics_overexpression_promote hsa-mir-545 Neoplasms [unspecific] 25299640 The miR-545/374a cluster encoded in the Ftx lncRNA is overexpressed in HBV-related hepatocellular carcinoma and promotes tumorigenesis and tumor progression. genetics_overexpression_promote hsa-mir-200c Breast Neoplasms 25329395 Overexpression of microRNA-200c predicts poor outcome in patients with PR-negative breast cancer. genetics_overexpression_promote hsa-mir-184 "Squamous Cell Carcinoma, Head and Neck" 25351569 Treatment with the precursors of these miRNAs increases the proliferation and migration of HNSCC cells. genetics_overexpression_promote hsa-mir-1269 "Carcinoma, Hepatocellular" 25472505 "overexpression of miR-1269 promotes cell proliferation in HCC through directly suppressing FOXO1, and functions as an oncomiR in HCC." genetics_overexpression_promote hsa-mir-17 Hematologic Neoplasms 25597017 overexpression of miR-17-92 in a limited number of hematopoietic cells is sufficient to cause B cell malignancies. genetics_overexpression_promote hsa-mir-34a Sensorineural Hearing Loss 25638533 "In the inner ear HEI-OC1 cell line, miR-34a overexpression inhibited SIRT1, leading to an increase in p53 acetylation and apoptosis." genetics_overexpression_promote hsa-mir-29c Brain Disease [unspecific] 25678279 "over-expression of miR-29c effectively reduced Birc2 (also Bak1) mRNA and protein levels, increased infarct volume and apoptosis, and deteriorated neurological outcomes, whereas down-regulation played a neuroprotective role." genetics_overexpression_promote hsa-mir-433 Ovarian Neoplasms 25684390 Overexpression of the microRNA miR-433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells. genetics_overexpression_promote hsa-mir-221 Neoplasms [unspecific] 25686829 Over-expression of miR-221 stimulated stem-like cells in luminal type of cancer and the miR-221 level was correlated with clinical outcome in breast cancer patients. genetics_overexpression_promote hsa-mir-153 "Carcinoma, Hepatocellular" 25714700 Over-expression of miR-153 down-regulated the activity of Etoposide and Paclitaxel on cell cycle arrest of HepG2 cells and the effect of Sorafenib on the invasion and migration of HepG2 cells. genetics_overexpression_promote hsa-mir-196a "Squamous Cell Carcinoma, Head and Neck" 25860510 "These results show that miR-196a and HOXB9 are overexpressed,perhaps co-ordinately, as HNSCC develops and exert a pro-tumourigenic phenotype in HNSCC and OPM cells." genetics_overexpression_promote hsa-mir-21 "Carcinoma, Cervical" 25963606 Overexpression of miR-21 promotes the proliferation and migration of cervical cancer cells via the inhibition of PTEN. genetics_overexpression_promote hsa-mir-125a Chronic Hepatitis B 25993287 "Conversely, the overexpression of miR-125a or knockdown of A20 mimicked HBx to enhance TRAIL susceptibility in hepatocytes." genetics_overexpression_promote hsa-mir-196a Osteosarcoma 26045752 "Taken together, miR-196a should be an oncogene in osteosarcoma. The possible mechanism was that overexpression of miR-196a promoted proliferation of MG63 and U2OS cells by modulating the PTEN/PI3K/Akt signaling pathway." genetics_overexpression_promote hsa-mir-221 "Carcinoma, Lung, Non-Small-Cell" 26131134 We found that miR-222 overexpression increased cell viability and proliferative rate in H460 cells while opposite effects were obtained by down-regulation of miR-222. genetics_overexpression_promote hsa-mir-144 Diabetic Cardiomyopathies 26164195 The miR-144 mimics aggravated high glucose-induced ROS formation and apoptosis in cardiomyocytes genetics_overexpression_promote hsa-mir-23a "Carcinoma, Laryngeal" 26171041 "Ectopic expression of miR-23a and knockdown of APAF-1 significantly promoted cell proliferation and colony formation, and inhibited early apoptosis in Hep2 cells." genetics_overexpression_promote hsa-mir-132 "Diabetes Mellitus, Type 2" 26218441 Overexpression of miR-132 or miR-212 enhances glucose and GLP-1-stimulated insulin secretion. genetics_overexpression_promote hsa-mir-212 "Diabetes Mellitus, Type 2" 26218441 Overexpression of miR-132 or miR-212 enhances glucose and GLP-1-stimulated insulin secretion. genetics_overexpression_promote hsa-mir-331 Prostate Neoplasms 26259043 "Overexpression of miR-331-3p upregulated mesenchymal markers such as vimentin, N-cadherin, and snail and downregulated epithelial markers such as E-cadherin and desmoplakin in the prostate cancer cell line PC3." genetics_overexpression_promote hsa-mir-93 "Squamous Cell Carcinoma, Esophageal" 26273410 "The introduction of miR-93 significantly promotes cell proliferation,cell cycle progression, and the metastatic capability of EC109 cells. " genetics_overexpression_promote hsa-mir-20a Gastric Neoplasms 26286834 "ectopic expression of miR-20a dramatically decreased the expression of NFKBIB; increased the expression of p65, livin, and survivin" genetics_overexpression_promote hsa-mir-215 Glioma 26317904 "In summary, miR-215 is overexpressed in human glioma, is involved in TGF-¦Â1-induced oncogenesis, and can be used as a marker of poor prognosis in glioma patients." genetics_overexpression_promote hsa-mir-206 Cardiomegaly 26333362 Cardiac-specific overexpression of miR-206 in mice induced hypertrophy and protected the heart from ischemia/reperfusion injury genetics_overexpression_promote hsa-mir-1207 Ovarian Neoplasms 26337084 MiR-1207 overexpression promotes cancer stem cell-like traits in ovarian cancer by activating the Wnt/¦Â-catenin signaling pathway. genetics_overexpression_promote hsa-mir-302 Fanconi Anemia 26343459 "Taken together, our results suggest that overexpression of miR-302 plays a critical role in the regulation of FANCD2 monoubiquitination, resulting in characteristic defects in DNA repair within cells." genetics_overexpression_promote hsa-mir-92a "Carcinoma, Lung, Non-Small-Cell" 26432332 "upregulation of miR-92a in NSCLC cells promoted cell proliferation, migration, and invasion, decreased apoptosis and caspase-3 activity, and enhanced chemoresistance of NSCLC cells, whereas downregulation of miR-92a showed the opposite effects." genetics_overexpression_promote hsa-mir-451 "Squamous Cell Carcinoma, Head and Neck" 26506880 And overexpression of miRNA-451 in cells with low endogenous expression of miRNA-451 accelerated proliferation. genetics_overexpression_promote hsa-mir-664 Osteosarcoma 26515813 Overexpression of miR-664 was associated with increased migration and invasive abilities of OS cells in vitro genetics_overexpression_promote hsa-mir-221 Inflammation 26549234 Enforced expression of miR-221 significantly increased the production of proinflammatory cytokines genetics_overexpression_promote hsa-mir-21 Asthma 26651881 "This study provides the first in vitro evidence that overexpression of miR-21 in HASM cells can trigger cell proliferation and migration, and the effects of miR-21 depend on the level of PTEN." genetics_overexpression_promote hsa-mir-27b Cervical Neoplasms 26706910 "Upregulation of miR-27b significantly accelerated the proliferation, cell cycle transition from G1 to S phase, migration and invasion of C33A cells" genetics_overexpression_promote hsa-mir-183 Colorectal Carcinoma 26717041 "over-expression of miR-183 resulted in the attenuation of rapamycin- or starvation-induced autophagy in cancer cells, whereas inhibition of endogenous miR-183 stimulated autophagy and apoptosis." genetics_overexpression_promote hsa-mir-200a "Carcinoma, Nasopharyngeal" 26718506 Overexpression of miR-200a resulted in the proliferation of CNE2 cells. genetics_overexpression_promote hsa-mir-203 Pancreatic Neoplasms 26719072 "miR-203 promotes proliferation, migration and invasion in pancreatic cancer cells" genetics_overexpression_promote hsa-mir-421 Osteosarcoma 26758431 "overexpression of miR-421 promoted osteosarcoma cell line MG-63 proliferation, migration, and invasion." genetics_overexpression_promote hsa-mir-21 Osteosarcoma 26779632 miR-21 overexpression in MG63 caused a significant raise in cell proliferation and invasion and a significant reduction in cell apoptosis. genetics_overexpression_promote hsa-mir-222 Bladder Neoplasms 26800397 Overexpression of miR-222 attenuated cisplatin-induced cell death in bladder cancer cells. genetics_overexpression_promote hsa-mir-96 Glioma 26846266 "In vivo, microRNA-96 overexpression inhibits the apoptosis and increases tumor growth." genetics_overexpression_promote hsa-mir-21 Heart Failure 26865549 Overexpression of miR-21 in this monocyte cell line activated a fibrotic gene programme and promoted monocyte-to-fibrocyte transition genetics_overexpression_promote hsa-mir-183 Glioma 26879754 "Introduction of miR-183 mimics into U251 cells could promoted, while its antisense oligos inhibited cell proliferation and invasion." genetics_overexpression_promote hsa-mir-205 "Carcinoma, Nasopharyngeal" 26880795 "Overexpression of miR-205 increased the proliferation, migration and invasion of CNE2 cells" genetics_overexpression_promote hsa-mir-21 "Carcinoma, Cervical" 26884851 "The overexpression of HPV E7 protein facilitated the expression of miR-21, which potentiated Hela cell proliferation and invasion." genetics_overexpression_promote hsa-mir-138 Glioblastoma 26887050 Transient transfection of miR-138 mimics in glioma cells with low basal miR-138 expression increased glioma cell proliferation. genetics_overexpression_promote hsa-mir-27b Cervical Neoplasms 26910911 "MiR-27b, up-regulated by E7, promoted CaSki and SiHa cell proliferation and invasion, inhibit paclitaxel-induced apoptosis." genetics_overexpression_promote hsa-mir-195 Spinal Cord Injuries 26927342 "In addition, Ad-miR-195 also obviously increased the number of apoptotic cells and decreased the neurological recovery in the animals injected with Ad-miR-195." genetics_overexpression_promote hsa-mir-449a Breast Neoplasms 26934316 "In vitro, miR-449a promoted breast cancer cell proliferation, clonogenic survival, migration, and invasion." genetics_overexpression_promote hsa-mir-214 Breast Neoplasms 26951965 the overexpression of miRâ€?14 markedly increased cell viability and abrogated the apoptosis triggered by serum starvation genetics_overexpression_promote hsa-mir-522 "Carcinoma, Hepatocellular" 26960688 "miR-522 overexpression promoted cell proliferation, colony formation, and cell cycle progression, whereas knockdown of miR-522 reduced these effects." genetics_overexpression_promote hsa-mir-210 Kidney Neoplasms 26985942 ACHN cell proliferation and invasion were significantly increased and apoptosis was significantly decreased (P < 0.05) when miR-210 was overexpressed. genetics_overexpression_promote hsa-mir-146a Chronic Hepatitis B 26996068 Overexpression of miR-146a reduced NK cell-mediated cytotoxicity genetics_overexpression_promote hsa-mir-141 "Carcinoma, Nasopharyngeal" 27010857 ectopic expression of miR-141 can significantly promote cell proliferation and inhibit apoptosis in NPC genetics_overexpression_promote hsa-mir-125a Juvenile Rheumatoid Arthritis 27014994 miR-125a-5p overexpression enhanced M2b polarization and altered other polarized populations genetics_overexpression_promote hsa-mir-195 Myocardial Ischemic-Reperfusion Injury 27019437 "miR-195 expression was upregulated in myocardial I/R injury, and miR-195 overexpression may promote cardiomyocyte apoptosis by targeting Bcl-2 and inducing mitochondrial apoptotic pathway." genetics_overexpression_promote hsa-mir-93 "Carcinoma, Gastric" 27021515 miR-93 promoted the development of gastric tumor growth in xenograft mice genetics_overexpression_promote hsa-mir-9 Glioblastoma 27036038 "hsa-miR-9 overexpression leads to MAPKAP signaling inhibition, partially by interfering with the MAPK14/MAPKAP3 complex. Further, hsa-miR-9 overexpression initiates re-arrangement of actin filament" genetics_overexpression_promote hsa-mir-221 Breast Neoplasms 27044817 "Enforced expression of miR-221/222 promoted breast cancer cell proliferation, migration and invasion via targeting PTEN/Akt pathway." genetics_overexpression_promote hsa-mir-222 Breast Neoplasms 27044817 "Enforced expression of miR-221/222 promoted breast cancer cell proliferation, migration and invasion via targeting PTEN/Akt pathway." genetics_overexpression_promote hsa-mir-373 "Squamous Cell Carcinoma, Esophageal" 27073718 "Overexpression of miR-373 in ECA109 cells enhanced proliferation, G1-phase cell proportion, migration, and invasion." genetics_overexpression_promote hsa-mir-141 Breast Neoplasms 27075851 "Ectopic expression of miR-141 in nonexpressing MDA-MB-231 enhanced brain metastatic colonization (5/9 mice vs 0/10 mice,P= .02)." genetics_overexpression_promote hsa-mir-92b "Carcinoma, Hepatocellular" 27100897 miR-92b could promote cell proliferation and metastasis of HCC in vitro and in vivo. genetics_overexpression_promote hsa-mir-146a Multiple Myeloma 27102001 "overexpressing miR-146a in MSC, secretion of several cytokines and chemokines including CXCL1, IL6, IL-8, IP-10, MCP-1, and CCL-5 was elevated, resulting in the enhancement of MM cell viability and migration." genetics_overexpression_promote hsa-mir-196a "Carcinoma, Hepatocellular" 27108614 "HCV core protein increased the expression of miRâ€?96a, and that overexpression of miRâ€?96a in the HepG2 and Huhâ€? HCC cell lines promoted cell proliferation by inducing the G1‑S transition." genetics_overexpression_promote hsa-mir-449a Hepatitis B Virus Infection 27138288 "Ectopic miR-449a expression in HCC cells strongly enhanced HBV replication, transcription, progeny virions secretion, and antigen expression in a dose-dependent manner." genetics_overexpression_promote hsa-mir-106a Gastric Neoplasms 27142596 "Abnormal over-expression of miR-106a significantly promoted gastric cancer cell proliferation, metastasis, inhibited the cell apoptosis." genetics_overexpression_promote hsa-mir-96 "Carcinoma, Prostate" 27164937 Overexpressing miR-96 led to increased proliferation and colony formation of normal prostate epithelial cells. genetics_overexpression_promote hsa-mir-410 Colorectal Carcinoma 27177325 overexpression of miRâ€?10 resulted in an increase in growth activity and decrease in the extent of apoptosis genetics_overexpression_promote hsa-mir-937 Lung Neoplasms 27179609 Overexpression of miR-937 in A549 promoted anchorage -dependent and -independent growth genetics_overexpression_promote hsa-mir-200b "Cytotoxicity Tests, Immunologic" 27183614 Cells overexpressing miR-200b/c or miR-217 showed reduced sensitivity to CDC genetics_overexpression_promote hsa-mir-200c "Cytotoxicity Tests, Immunologic" 27183614 Cells overexpressing miR-200b/c or miR-217 showed reduced sensitivity to CDC genetics_overexpression_promote hsa-mir-217 "Cytotoxicity Tests, Immunologic" 27183614 Cells overexpressing miR-200b/c or miR-217 showed reduced sensitivity to CDC genetics_overexpression_promote hsa-mir-182 Liver Injury 27196584 "miR-182, which is associated with disease severity and liver injury." genetics_overexpression_promote hsa-mir-126 "Neovascularization, Pathologic" 27203443 "silencing of miR-126-3p repressed angiogenesis, while overexpression of miR-126-5p enhanced angiogenesis." genetics_overexpression_promote hsa-mir-21 Hypertrophic Scar 27207585 overexpression of miR-21 promoted fibroproliferative expression in fibroblasts. genetics_overexpression_promote hsa-mir-125b "Carcinoma, Gastric" 27220320 Overexpression of miR-125b promoted gastric cancer cell migration and invasion in vitro and metastasis in vivo. genetics_overexpression_promote hsa-mir-211 "Squamous Cell Carcinoma, Oral" 27221705 Induction of oral carcinogenesis in transgenic mice using 4-nitroquinoline 1-oxide (4NQO) resulted in more extensive and severe tongue tumorigenesis compared with control animals. genetics_overexpression_promote hsa-mir-221 "Adenocarcinoma, Pancreatic Ductal" 27230035 Overexpressing miR-221 significantly increased cell vitality and promoted cell proliferation and G1-to-S phase transition of the cell cycle in Capan-2 cells genetics_overexpression_promote hsa-mir-146a Alzheimer Disease 27241555 "Overexpression of miRNA-146a in SH-SY5Y cells significantly decreased Lrp2 expression, resulting in a reduction of Akt activation and induction of proapoptotic caspase-3, thereby increasing cell apoptosis." genetics_overexpression_promote hsa-mir-182 Cerebral Ischemia 27242323 miR-182 plays an aggressive role in the cerebral ischemia injury genetics_overexpression_promote hsa-mir-34a Osteoarthritis 27247228 Overexpression of miR-34a promoted apoptosis and inhibited cell proliferation in human chondrocytes genetics_overexpression_promote hsa-mir-1908 Wound Healing 27256397 miR-1908 had a positive role in scar formation genetics_overexpression_promote hsa-mir-1301 Prostate Neoplasms 27261573 miR-1301 promoted cell proliferation of prostate cancer. genetics_overexpression_promote hsa-mir-205 Colorectal Carcinoma 27271572 miR-205 and miR-373 may differentially contribute to the aggressive phenotype of MAC in CRC. genetics_overexpression_promote hsa-mir-373 Colorectal Carcinoma 27271572 miR-205 and miR-373 may differentially contribute to the aggressive phenotype of MAC in CRC. genetics_overexpression_promote hsa-mir-206 Alzheimer Disease 27277332 miRâ€?06 upregulation enhanced LPS‑induced inflammation and Aβ release in microglia genetics_overexpression_promote hsa-mir-21 Neuroblastoma 27285119 "Forced overexpression of miR-21 significantly increased NB cell proliferation, migration, and invasion." genetics_overexpression_promote hsa-mir-18a "Squamous Cell Carcinoma, Esophageal" 27291152 upregulation of miR-18a promoted cell proliferation by increasing cylin D1 genetics_overexpression_promote hsa-mir-429 Diabetes Mellitus 27299781 "increased miR-429 could down-regulate the expression of Ocln by targeting the Ocln 3'-UTR, which impaired intestinal barrier function in DM mice." genetics_overexpression_promote hsa-mir-9 Influenza 27322373 Overexpression of miR-9 enhanced viral gene expression and production of infectious progeny genetics_overexpression_promote hsa-mir-222 Gastric Neoplasms 27323780 "Gastrin-induced miR-222 overexpression resulted in reduced expression and cytoplasmic mislocalisation of p27kip1, which in turn caused actin remodelling and increased migration in AGSGR cells." genetics_overexpression_promote hsa-mir-19a Glioma 27329239 Overexpression of miR-19a by a miR-19a mimic promoted glioma cell proliferation and invasion. genetics_overexpression_promote hsa-mir-548a "Carcinoma, Hepatocellular" 27340352 "overexpression of miR-548a-5p in HCC cell lines promoted cell proliferation, increased colony forming ability and hampered cell apoptosis." genetics_overexpression_promote hsa-mir-29a Atrial Fibrillation 27341015 miR-29a-3p transfection in cardiomyocytes produced the effects on the ICa genetics_overexpression_promote hsa-mir-301b Lung Neoplasms 27352910 "ectopic expression of miR-301b enhanced cell population growth, reduced apoptosis and reduced sensitivity of cells to chemotherapy." genetics_overexpression_promote hsa-mir-20a Uveal Melanoma 27356499 "miRâ€?0a mimics were transfected into UM cells, which led to increases in cell growth, migration and invasion activities." genetics_overexpression_promote hsa-mir-92a "Carcinoma, Nasopharyngeal" 27366095 miR-92a overexpression potentiated the migration and invasion of 6-10B cells genetics_overexpression_promote hsa-mir-340 Gastric Neoplasms 27374211 "Functionally, forced expression of miR-340 promoted cell viability, proliferation, colony formation and cell cycle progression in the SGC-7901 cells" genetics_overexpression_promote hsa-mir-21 Cholesteatoma 27376830 miR-21 promotes the proliferation and invasion of cholesteatoma keratinocytes. genetics_overexpression_promote hsa-mir-488 Osteosarcoma 27376839 "We also found that exogenous over-expression of microRNA-488 promotes the proliferation, reduces the apoptosis and decreases the sensitivity to chemotherapy (doxorubicin) of osteosarcoma cells" genetics_overexpression_promote hsa-mir-205 Myelodysplastic Syndromes 27379838 Our findings suggest that miR-205-5p upregulation contributes to MDS by suppressing PTEN and that miR-205-5p thus acts as an oncogene in hematopoietic cells. genetics_overexpression_promote hsa-mir-181b Gastric Neoplasms 27383203 Overexpression of miR-181b mimic induced an in vitro EMT-like change to a phenotype similar to that following TGF-β treatment alone and was reversed by miRNA-181b inhibitor. genetics_overexpression_promote hsa-mir-27a Gastric Neoplasms 27409164 "And overexpression of miR-27a-3p, but not miR-27a-5p, markedly promoted gastric cancer cell proliferation in vitro as well as tumor growth in vivo." genetics_overexpression_promote hsa-mir-92a Acute Myocardial Infarction 27411964 "Further, it could be observed in cellular experiments that treatment of miR-92a mimics can further upregulate endothelial injury markers." genetics_overexpression_promote hsa-mir-92b Bladder Neoplasms 27430302 "In this study, we demonstrated that miR-92b could uniquely promote cell migration and invasion of BCa cells, but had no effect on cell proliferation." genetics_overexpression_promote hsa-mir-1303 Neuroblastoma 27434867 "miR-1303 overexpression promoted the proliferation of SH-SY5Y NB cell investigated by MTT assay, colony formation assay and anchorage-independent growth ability assay, while miR-1303 knockdown reduced this effect." genetics_overexpression_promote hsa-mir-146a Cerebral Ischemia 27449900 "In conclusion, our study revealed that miR-146a contributes to OGD/R injury in vitro." genetics_overexpression_promote hsa-mir-940 "Carcinoma, Pancreatic" 27459115 Over-expression of microRNA-940 promotes cell proliferation by targeting GSK3β and sFRP1 in human pancreatic carcinoma. genetics_overexpression_promote hsa-mir-181a Atherosclerosis 27460740 The exogenous overexpression of miR-181a accelerates the apoptosis rates of HUVECs in response to H2O2. genetics_overexpression_promote hsa-mir-769 Melanoma 27470346 "Overexpression of miR-769 promoted cell proliferation in human melanoma cell line A375, whereas miR-769-in reverses the function." genetics_overexpression_promote hsa-mir-183 "Carcinoma, Breast" 27476679 Overexpression of miR-183-5p significantly enhanced the cell proliferation and inhibited cell apoptosis in MCF-7 and MDA-MB-231 cells. genetics_overexpression_promote hsa-mir-194 "Carcinoma, Ovarian" 27486333 "Overexpression of miR-194 in ovarian cancer cells promotes cell proliferation, migration, and invasion; in contrast, inhibition of the expression of miR-194 has the opposite effects." genetics_overexpression_promote hsa-mir-195 Myocardial Ischemic-Reperfusion Injury 27489501 Up-regulation of miR-195 in ischemic cardiomyocytes promotes ischemic apoptosis by targeting Bcl-2. genetics_overexpression_promote hsa-mir-363 Glioma 27495233 "Transfection of miR-363 induced cell survival, while inhibition of miR-363 significantly reduced glioma cell viability." genetics_overexpression_promote hsa-mir-200c "Carcinoma, Gastric" 27498672 "Finally, ectopic expression of miR-200c or knockdown of DNMT3a expression impeded GC cell growth, migration and invasion." genetics_overexpression_promote hsa-mir-15b "Carcinoma, Hepatocellular" 27499071 "It was observed that high expression of miR-15b promoted cell proliferation of the HCC cells, while low expression of miR-15b suppressed cell growth and induced the apoptosis of HepG2 cells." genetics_overexpression_promote hsa-mir-17 Macular Degeneration 27505139 Transfection of miR-17-3p mimic in ARPE-19 induced cell death and exacerbated oxidative lethality that was alleviated by miR-17-3p inhibitor. genetics_overexpression_promote hsa-mir-19b Lung Fibrosis 27508324 "Overexpression of miR-19b in small-airway epithelial cells promoted the mechanical stretch-induced EMT phenotypes, whereas inhibition of miR-19b attenuated it." genetics_overexpression_promote hsa-mir-1 "Carcinoma, Colon" 27511117 overexpression of PIK3CA-premir1 in HCT116 and SW480 cells resulted in significant reduction of the sub-G1 cell distribution and apoptotic cell rate and resulted in increased cell proliferation. genetics_overexpression_promote hsa-mir-483 "Carcinoma, Gastric" 27511210 overexpression of miRâ€?83â€?p by transfection with miRâ€?83â€?p mimics significantly increased cell proliferation and Annexin V‑propidium iodide staining indicated the suppression of cell apoptosis. genetics_overexpression_promote hsa-mir-125b Retinoblastoma 27518550 overexpression of miR-125b apparently promotes RB cell proliferation and migration in vitro. genetics_overexpression_promote hsa-mir-31 "Squamous Cell Carcinoma, Head and Neck" 27528032 miR-31 associated oncogenicities were rescued by ARID1A expression in HNSCC cells. genetics_overexpression_promote hsa-mir-15b Neoplasms [unspecific] 27530410 increased miR-15b and decreased RECK expression may contribute to the pathobiology of LYO. genetics_overexpression_promote hsa-mir-15b Uterine Leiomyoma 27530410 "Our findings suggest that miR-15b negatively regulates RECK expression in LYO, and increased miR-15b and decreased RECK expression may contribute to the pathobiology of LYO." genetics_overexpression_promote hsa-mir-375 Liver Failure 27531059 "Thus miR-375 is identified as a novel repressor of UGT1A-mediated hepatic acetaminophen glucuronidation through reduced AhR expression, which could predispose some individuals to increased risk for acetaminophen-induced ALF" genetics_overexpression_promote hsa-mir-181a "Leukemia, Myeloid, Acute" 27531761 Overexpression of miR-181a can promote AML cell proliferation. genetics_overexpression_promote hsa-mir-29b Hearing Loss 27635430 miR-29b overexpression induces cochlear hair cell apoptosis through the regulation of SIRT1/PGC-1¦Á signaling: Implications for age-related hearing loss. genetics_overexpression_promote hsa-mir-1288 "Squamous Cell Carcinoma, Esophageal" 27658568 Overexpression of miR-1288 play a key role in thepathogenesis of ESCCs and its modulation may have potential therapeutic value in patients with ESCC genetics_overexpression_promote hsa-mir-9 Osteosarcoma 27724924 MiR-9 is overexpressed in spontaneous canine osteosarcoma and promotes a metastatic phenotype including invasion and migration in osteoblasts and osteosarcoma cell lines. genetics_overexpression_promote hsa-mir-760 "Carcinoma, Ovarian" 27726922 MiR-760 overexpression promotes proliferation in ovarian cancer by downregulation of PHLPP2 expression. genetics_overexpression_promote hsa-mir-182 "Squamous Cell Carcinoma, Head and Neck" 27744260 Overexpression of TP53 mutation-associated microRNA-182 promotes tumor cell proliferation and migration in head and neck squamous cell carcinoma. genetics_overexpression_promote hsa-mir-138 Obesity 27762728 miR-138/miR-222 Overexpression Characterizes the miRNome of Amniotic Mesenchymal Stem Cells in Obesity. genetics_overexpression_promote hsa-mir-222 Obesity 27762728 miR-138/miR-222 Overexpression Characterizes the miRNome of Amniotic Mesenchymal Stem Cells in Obesity. genetics_overexpression_promote hsa-mir-212 "Adenocarcinoma, Pancreatic Ductal" 27814273 Overexpressions of miR-212 are associated with poor prognosis of patients with pancreatic ductal adenocarcinoma. genetics_overexpression_promote hsa-mir-21 Choriocarcinoma 27922982 "miR-21 Is Overexpressed in Hydatidiform Mole Tissues and Promotes Proliferation, Migration, and Invasion in Choriocarcinoma Cells." genetics_overexpression_promote hsa-mir-675 "Squamous Cell Carcinoma, Head and Neck" 27994496 Overexpression of lncRNA H19/miR-675 promotes tumorigenesis in head and neck squamous cell carcinoma. genetics_overexpression_promote hsa-mir-375 Diabetes Mellitus 28017506 Insulin producing cells generation by overexpression of miR-375 in adipose-derived mesenchymal stem cells from diabetic patients. genetics_overexpression_promote hsa-mir-223 Glioblastoma 28035389 "overexpression of miR-223 increases TMZ chemoresistance, while inhibition of miR-223 with antagomir markedly decreases TMZ chemoresistance in GBM cells" genetics_overexpression_promote hsa-mir-92a Osteosarcoma 28069547 Overexpression of miR-92a promotes the tumor growth of osteosarcoma by suppressing F-box and WD repeat-containing protein 7. genetics_overexpression_promote hsa-mir-205 Endometrial Neoplasms 28105153 Overexpression of microRNA-205 predicts lymph node metastasis and indicates an unfavorable prognosis in endometrial cancer. genetics_overexpression_promote hsa-mir-196b Myelodysplastic Syndromes 28224273 Over-expression of miR-196b-5p is significantly associated with the progression of myelodysplastic syndrome. genetics_overexpression_promote hsa-mir-214 Osteosarcoma 28260089 Overexpression of miR?214 promotes the progression of human osteosarcoma by regulating the Wnt/¦Â?catenin signaling pathway. genetics_overexpression_promote hsa-mir-320 Ovarian Neoplasms 28338235 Overexpression of Hsa-miR-320 Is Associated With Invasion and Metastasis of Ovarian Cancer. genetics_overexpression_promote hsa-mir-10b Colorectal Carcinoma 28345456 Overexpression of miR-10b in colorectal cancer patients: Correlation with TWIST-1 and E-cadherin expression. genetics_overexpression_promote hsa-mir-221 Ovarian Neoplasms 28350128 Overexpression of miRNA-221 promotes cell proliferation by targeting the apoptotic protease activating factor-1 and indicates a poor prognosis in ovarian cancer. genetics_overexpression_promote hsa-mir-196b "Carcinoma, Ovarian" 28387653 Overexpression of microRNA-196b Accelerates Invasiveness of Cancer Cells in Recurrent Epithelial Ovarian Cancer Through Regulation of Homeobox A9. genetics_overexpression_promote hsa-mir-1 Myocardial Infarction 28397788 Over-expression of microRNA-1 causes arrhythmia by disturbing intracellular trafficking system. genetics_overexpression_promote hsa-mir-34a Colorectal Adenocarcinoma 28624481 "miR-34a overexpression predicts poor prognostic outcome in colorectal adenocarcinoma, independently of clinicopathological factors with established prognostic value." genetics_overexpression_promote hsa-let-7 "Carcinoma, Hepatocellular" 28796071 Overexpression of microRNA let-7 correlates with disease progression and poor prognosis in hepatocellular carcinoma genetics_overexpression_promote hsa-let-7a "Carcinoma, Hepatocellular" 28796071 Overexpression of microRNA let-7 correlates with disease progression and poor prognosis in hepatocellular carcinoma genetics_overexpression_promote hsa-let-7e "Carcinoma, Hepatocellular" 28796071 Overexpression of microRNA let-7 correlates with disease progression and poor prognosis in hepatocellular carcinoma genetics_overexpression_promote hsa-mir-194 Colorectal Carcinoma 29109785 Overexpression of miR-194 Reverses HMGA2-driven Signatures in Colorectal Cancer. genetics_overexpression_promote hsa-mir-10b Neoplasms [unspecific] 29262659 "the overexpression of miR-10b was significantly correlated with metastasis status, and indicated the potential clinical use of miR-10b as a molecular biomarker, particularly in assessing prognosis for patients with cancers" genetics_overexpression_promote hsa-mir-130a "Leukemia, Myeloid, Acute" 29493383 MiR-130a is aberrantly overexpressed in adult acute myeloid leukemia with t(8;21) and its suppression induces AML cell death. genetics_overexpression_promote hsa-mir-155 "Leukemia, Myeloid, Acute" 29657293 miR-155 overexpression plays a key pathogenic role in some lymphomas and acute myeloid leukemias has led to the development of an antagomir-based approach as a new promising therapeutic strategy genetics_overexpression_promote hsa-mir-19a Multiple Myeloma 29665917 "miR-19a is overexpressed significantly in Lp-1 and U266 multiple myeloma cells, and promots the proliferation and invasion of the myeloma cells, but inhibits their apoptosis" genetics_overexpression_promote hsa-mir-34a Pituitary Adenoma 30109259 Overexpression of microRNA-34a Attenuates Proliferation and Induces Apoptosis in Pituitary Adenoma Cells via SOX7. genetics_overexpression_promote hsa-mir-221 "Carcinoma, Breast" 30110679 Our findings provide strong evidence that miR-9 and miR-221 can enhance the generation of cancer stem cells to yield an invasive phenotype and that overexpression of these miRNAs predicts a poor outcome for breast cancer patients genetics_overexpression_promote hsa-mir-9 "Carcinoma, Breast" 30110679 Our findings provide strong evidence that miR-9 and miR-221 can enhance the generation of cancer stem cells to yield an invasive phenotype and that overexpression of these miRNAs predicts a poor outcome for breast cancer patients genetics_overexpression_promote hsa-mir-214 Myeloma 30357841 "Bone marrow fibroblasts overexpress miR-27b and miR-214 in step with multiple myeloma progression, dependent on tumour cell-derived exosomes." genetics_overexpression_promote hsa-mir-27b Myeloma 30357841 "Bone marrow fibroblasts overexpress miR-27b and miR-214 in step with multiple myeloma progression, dependent on tumour cell-derived exosomes." genetics_overexpression_promote hsa-mir-301a Colorectal Carcinoma 30362160 Overexpression of miR-301a-3p promotes colorectal cancer cell proliferation and metastasis by targeting deleted in liver cancer-1 and runt-related transcription factor 3. genetics_overexpression_promote hsa-mir-361 "Adenocarcinoma, Lung" 30365047 Overexpression of miR?361?5p plays an oncogenic role in human lung adenocarcinoma through the regulation of SMAD2. genetics_overexpression_suppress hsa-mir-125b-1 "Carcinoma, Hepatocellular" 18649363 miR-125b: overexpression of miR-125b in HCC cell line could obviously suppress the cell growth and phosporylation of Akt genetics_overexpression_suppress hsa-mir-125b-2 "Carcinoma, Hepatocellular" 18649363 miR-125b: overexpression of miR-125b in HCC cell line could obviously suppress the cell growth and phosporylation of Akt genetics_overexpression_suppress hsa-mir-142 Lung Neoplasms 19228723 "miR-142-5p: were repressed, overexpression can inhibitu lung cancer growth" genetics_overexpression_suppress hsa-mir-145 Lung Neoplasms 19228723 "miR-145: were repressed, overexpression can inhibitu lung cancer growth" genetics_overexpression_suppress hsa-mir-34c Lung Neoplasms 19228723 "miR-34c: were repressed, overexpression can inhibitu lung cancer growth" genetics_overexpression_suppress hsa-mir-100 Ovarian Neoplasms 20081105 "Overexpression of mir-100 inhibited mTOR signaling and enhanced sensitivity to the rapamycin analog RAD001 (everolimus), confirming the key relationship between mir-100 and the mTOR pathway." genetics_overexpression_suppress hsa-mir-22 Ovarian Neoplasms 20081105 "overexpression of the putative tumor suppressor mir-22 repressed the EVI1 oncogene, which is known to suppress apoptosis by stimulating phosphatidylinositol 3-kinase/v-akt murine thymoma viral oncogene homolog 1 signaling." genetics_overexpression_suppress hsa-mir-194 Liver Neoplasms 20979124 The overexpression of miR-194 in liver mesenchymal-like cancer cells reduced the expression of the mesenchymal cell marker N-cadherin and suppressed invasion and migration of the mesenchymal-like cancer cells both in vitro and in vivo genetics_overexpression_suppress hsa-let-7a-1 Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. genetics_overexpression_suppress hsa-let-7a-2 Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. genetics_overexpression_suppress hsa-let-7a-3 Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. genetics_overexpression_suppress hsa-let-7b Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. genetics_overexpression_suppress hsa-let-7c Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. genetics_overexpression_suppress hsa-let-7d Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. genetics_overexpression_suppress hsa-let-7e Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. genetics_overexpression_suppress hsa-let-7f-1 Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. genetics_overexpression_suppress hsa-let-7f-2 Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. genetics_overexpression_suppress hsa-let-7g Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. genetics_overexpression_suppress hsa-let-7i Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. genetics_overexpression_suppress hsa-mir-98 Hypertrophy 21183740 Thioredoxin 1 Negatively Regulates Angiotensin II-Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7. genetics_overexpression_suppress hsa-mir-146a Atherosclerosis 21329689 Over-expression of miR-146a may be useful in the prevention and treatment of atherosclerosis. genetics_overexpression_suppress hsa-mir-128 Glioblastoma 21358821 "Our analysis predicted a significant association between miR-128 and the protein kinase WEE1, which we subsequently validated experimentally by showing that the over-expression of the naturally under-expressed miR-128 in glioma cells resulted in the inhibition of WEE1 in glioblastoma cells." genetics_overexpression_suppress hsa-mir-663 Leukemia 21518471 "miRNA-663 in K562 cells is up-regulated after 5-aza treatment. Over-expression of miR-663 can suppress the proliferation of K562 cells, which suggests that miR-663 may possesses suppressive effect for leukaemia." genetics_overexpression_suppress hsa-mir-146b Lung Neoplasms 21789255 Overexpression of the Lung Cancer-Prognostic miR-146b MicroRNAs Has a Minimal and Negative Effect on the Malignant Phenotype of A549 Lung Cancer Cells. genetics_overexpression_suppress hsa-mir-199a-1 "Carcinoma, Hepatocellular" 21847633 Lentivirus-Mediated Overexpression of MicroRNA-199a Inhibits Cell Proliferation of Human Hepatocellular Carcinoma. genetics_overexpression_suppress hsa-mir-199a-2 "Carcinoma, Hepatocellular" 21847633 Lentivirus-Mediated Overexpression of MicroRNA-199a Inhibits Cell Proliferation of Human Hepatocellular Carcinoma. genetics_overexpression_suppress hsa-mir-16 Acute Lung Injury 22185353 "Accordingly, over-expression of miR-16 could significantly suppress the luciferase activity of reporter fusion with the binding sites of TNF¦Á in its 3'UTR region, suggesting that miR-16 played its role in LPS-induced lung inflammation by a direct manner." genetics_overexpression_suppress hsa-mir-10a "Leukemia, Myeloid, Acute" 22348345 miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated Acute Myeloid Leukaemia and its suppression induces cell death. genetics_overexpression_suppress hsa-mir-143 Colon Neoplasms 22362069 "Overexpression of three miRNA (miR200c*, miR143*, and miR424*) significantly abrogated invasive potential." genetics_overexpression_suppress hsa-mir-200c Colon Neoplasms 22362069 "Overexpression of three miRNA (miR200c*, miR143*, and miR424*) significantly abrogated invasive potential." genetics_overexpression_suppress hsa-mir-424 Colon Neoplasms 22362069 "Overexpression of three miRNA (miR200c*, miR143*, and miR424*) significantly abrogated invasive potential." genetics_overexpression_suppress hsa-let-7a-1 Esophageal Neoplasms 22363450 "Curcumin treatment down-regulate the expressions of Notch-1 specific microRNAs miR-21 and miR-34a, and upregulated tumor suppressor let-7a miRNA." genetics_overexpression_suppress hsa-let-7a-2 Esophageal Neoplasms 22363450 "Curcumin treatment down-regulate the expressions of Notch-1 specific microRNAs miR-21 and miR-34a, and upregulated tumor suppressor let-7a miRNA." genetics_overexpression_suppress hsa-let-7a-3 Esophageal Neoplasms 22363450 "Curcumin treatment down-regulate the expressions of Notch-1 specific microRNAs miR-21 and miR-34a, and upregulated tumor suppressor let-7a miRNA." genetics_overexpression_suppress hsa-mir-29a Ovarian Neoplasms 22479643 over-expression of miR-29a in vitro repressed several anti-correlated genes (including DNMT3A and DNMT3B) and substantially decreased ovarian cancer cell viability. genetics_overexpression_suppress hsa-let-7a-1 Colorectal Carcinoma 22584434 High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease. genetics_overexpression_suppress hsa-let-7a-2 Colorectal Carcinoma 22584434 High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease. genetics_overexpression_suppress hsa-let-7a-3 Colorectal Carcinoma 22584434 High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease. genetics_overexpression_suppress hsa-mir-92a-1 "Carcinoma, Hepatocellular" 22587342 Oxidative DNA damage correlates with cell immortalization and mir-92 expression in hepatocellular carcinoma. genetics_overexpression_suppress hsa-mir-34b "Carcinoma, Lung, Non-Small-Cell" 22593438 Overexpression of miR-34b significantly reduced cell survival at lower than 4 Gy radiation doses. genetics_overexpression_suppress hsa-mir-223 Rheumatoid Arthritis 22903258 Overexpression of microRNA-223 in rheumatoid arthritis synovium controls osteoclast differentiation. genetics_overexpression_suppress hsa-let-7b "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 22918121 The enforced expression of let-7b in ALL cell lines with an MLL fusion gene inhibited their growth. genetics_overexpression_suppress hsa-mir-34a Melanoma 22969970 "These results suggest that overexpression of miR-34a and c suppresses invasive and generative potentials, respectively, in human malignant melanoma." genetics_overexpression_suppress hsa-mir-34c Melanoma 22969970 "All four melanoma cell lines showed significant expression of miR-34s - A375: miR-34a 0.6176, miR-34b 0.7625, miR-34c 0.7877; " genetics_overexpression_suppress hsa-mir-124 Medulloblastoma 23172372 "MiR-124 overexpression inhibits the proliferation of medulloblastoma cells, and this effect is mediated mostly through the action of miR-124 upon CDK6." genetics_overexpression_suppress hsa-mir-142 Gastric Neoplasms 23209550 Overexpression of miR-142-5p and miR-155 in Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma Resistant to Helicobacter pylori Eradication genetics_overexpression_suppress hsa-mir-155 Gastric Neoplasms 23209550 Overexpression of miR-142-5p and miR-155 in Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma Resistant to Helicobacter pylori Eradication genetics_overexpression_suppress hsa-mir-19b Cardiovascular Diseases [unspecific] 23443808 "Overexpression of miR-19b inhibited activation of the Wnt/¦Â-catenin signaling pathway in P19 cells, which may regulate cardiomyocyte differentiation." genetics_overexpression_suppress hsa-mir-133a Hypertension 23460283 "In vitro overexpression of miR-27a,-29a, and -133a inhibited cardiomyocyte hypertrophy and reduced collagen expression. " genetics_overexpression_suppress hsa-mir-27a Hypertension 23460283 "In vitro overexpression of miR-27a,-29a, and -133a inhibited cardiomyocyte hypertrophy and reduced collagen expression. " genetics_overexpression_suppress hsa-mir-29a Hypertension 23460283 "In vitro overexpression of miR-27a,-29a, and -133a inhibited cardiomyocyte hypertrophy and reduced collagen expression. " genetics_overexpression_suppress hsa-mir-155 Ovarian Neoplasms 23523916 overexpression of miR-155 may prevent tumorigenesis in human ovarian cancer through downregulation of CLDN1. genetics_overexpression_suppress hsa-mir-138-1 Neuroblastoma 23562653 miR-138 Overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivo genetics_overexpression_suppress hsa-mir-138-2 Neuroblastoma 23562653 miR-138 Overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivo genetics_overexpression_suppress hsa-mir-34a Gastric Neoplasms 24068565 "miR-34a over-expression could improve the sensitivity of gastric cancer cells against cisplatin-based chemotherapies, with PI3K/AKT/survivin signaling pathway possibly involved in the mechanism." genetics_overexpression_suppress hsa-mir-181b Atherosclerosis 24084690 overexpression of miR-181b in the aortic intima of apolipoprotein E-deficient mice and suppressed NF-¦ÊB signaling revealed by bioluminescence imaging and reduced target gene expression in the aortic arch in apolipoprotein E-deficient/NF-¦ÊB-luciferase transgenic mice. genetics_overexpression_suppress hsa-mir-129 Medulloblastoma 24093088 Overexpression of miR-129-5p using mimics decreased DAOY proliferation genetics_overexpression_suppress hsa-let-7a Neoplasms [unspecific] 24100239 Human Argonaute-3 specifically enhances the passenger strand expression and activity of the tumor suppressor microRNA let-7a. genetics_overexpression_suppress hsa-mir-486 Breast Neoplasms 24104550 "in vitro functional screening of the downregulated miRNAs in non-malignant and breast cancer cell lines identified several possible tumor suppressor miRNAs, including miR-193b, miR-193a-3p, miR-126, miR-134, miR-132, miR-486-5p, miR-886-3p, miR-195 and miR-497, showing reduced growth when re-expressed in cancer cells" genetics_overexpression_suppress hsa-let-7a "Diabetes Mellitus, Type 2" 24105413 "Expression of microRNA let-7a and let-7d, which are direct translational repressors of the IL-13 gene, was increased in skeletal muscle from T2DM patients. " genetics_overexpression_suppress hsa-mir-200c Melanoma 24120113 Overexpression of microRna-200c in CD44+CD133+ CSCS inhibits the cellular migratory and invasion as well as tumorigenicity in mice. genetics_overexpression_suppress hsa-mir-145 Melanoma 24248543 Overexpression of miR-145 increases the sensitivity of vemurafenib in drug-resistant colo205 cell line. genetics_overexpression_suppress hsa-mir-449a "Adenocarcinoma, Gastric" 24260067 The overexpression of miR-449a inhibited gastric adenocarcinoma cell growth and promoted cell apoptosis in the MGC-803 and SGC-7901 gastric adenocarcinoma cell lines. genetics_overexpression_suppress hsa-let-7a Ewing Sarcoma 24383407 "Restored let-7a expression inhibited cell proliferation, migration, as well as invasion; arrested cell cycle progression; and induced cell apoptosis of both cell lines." genetics_overexpression_suppress hsa-mir-133b Gastric Neoplasms 24443799 MiR-133b is frequently decreased in gastric cancer and its overexpression reduces the metastatic potential of gastric cancer cells. genetics_overexpression_suppress hsa-mir-24 Heart Failure 24454859 "In vivo delivery of miR-24 into a mouse MI model suppressed cardiac cell death, attenuated infarct size, and rescued cardiac dysfunction." genetics_overexpression_suppress hsa-mir-34a "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 24482044 Ectopic expression of miR-34a and miR-34c in Hep-2 cells significantly induced the cell proliferation and migration ability in vitro. genetics_overexpression_suppress hsa-mir-34c "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 24482044 Ectopic expression of miR-34a and miR-34c in Hep-2 cells significantly induced the cell proliferation and migration ability in vitro. genetics_overexpression_suppress hsa-mir-107 Breast Neoplasms 24482686 "Overexpression of miR-107 suppressed MDA-MB-231 cell proliferation and migration, meanwhile the cells were arrested at G0/G1 phase." genetics_overexpression_suppress hsa-mir-7 Liver Neoplasms 24491049 "Over-expression of miR-7 could significantly inhibit the growth of human lung cancer cells in vivo and in vitro, which might be related to the down-regulated expression of tumor growth-associated protein CGGBP1." genetics_overexpression_suppress hsa-mir-21 Atherosclerosis 24502419 "Further analysis confirmed that overexpression of miR-21 by transfection with miR-21 mimics notably attenuated lipid accumulation and lipid-laden foam cell formation in LPS-stimulated macrophages, which was reversely up-regulated when silencing miR-21 expression via anti-miR-21 inhibitor transfection, indicating a reverse regulator of miR-21 in LPS-induced foam cell formation." genetics_overexpression_suppress hsa-let-7c Ovarian Neoplasms 24507678 "After application of let-7c, number of T29A2+ cell clones was decreased significantly, however, after the application of Anti-let-7, the number of clones restored, and there was no significant difference compared with the negative control group." genetics_overexpression_suppress hsa-mir-29a Diabetes Mellitus 24578127 "Diabetic miR-29a transgenic mice had better nephrin levels, podocyte viability, and renal function and less glomerular fibrosis and inflammation reaction compared with diabetic wild-type mice." genetics_overexpression_suppress hsa-mir-206 Ovarian Neoplasms 24604205 microRNA-206 overexpression inhibits cellular proliferation and invasion of estrogen receptor ¦Á-positive ovarian cancer cells. genetics_overexpression_suppress hsa-mir-183 Neuropathic Pain 24612023 "Intrathecal administration of lentivirions expressing miR-183 downregulated SNL-induced increases in the expression of Nav1.3 and brain-derived neurotrophic factor (BDNF), which correlated with the significant attenuation of SNL-induced mechanical allodynia." genetics_overexpression_suppress hsa-mir-143 Leukemia 24626955 Overexpression of microRNA-143 inhibits growth and induces apoptosis in human leukemia cells. genetics_overexpression_suppress hsa-mir-499 Heart Failure 24646523 "We report that cardiac-abundant miR-499 could protect neonatal rat cardiomyocytes against H 2O 2-induced apoptosis. Increased miR-499 level favored survival, while decreased miR-499 level favored apoptosis." genetics_overexpression_suppress hsa-mir-499 Myocardial Infarction 24646523 "We report that cardiac-abundant miR-499 could protect neonatal rat cardiomyocytes against H 2O 2-induced apoptosis. Increased miR-499 level favored survival, while decreased miR-499 level favored apoptosis." genetics_overexpression_suppress hsa-mir-155 Glioblastoma 24705102 "Over-expression of miR-136 and miR-634 miRNAs negatively affected proliferation, but not migration, while expression of miR-155 reduced migration but did not affect the proliferation of LN229 cells." genetics_overexpression_suppress hsa-mir-155 Arthritis 24708712 Overexpression of miR-155 in the gouty SFMC leads to suppress SHIP-1 levels and enhance proinflammatory cytokines. genetics_overexpression_suppress hsa-mir-34a "Carcinoma, Renal Cell" 24765202 "The Cell Counting Kit-8 identified that transient forced expression of miR-34a inhibited cell growth and resulted in cell cycle arrest, which was evaluated by flow cytometry." genetics_overexpression_suppress hsa-mir-206 "Carcinoma, Hepatocellular" 24919811 "MicroRNA-206 overexpression promotes apoptosis, induces cell cycle arrest and inhibits the migration of human hepatocellular carcinoma HepG2 cells." genetics_overexpression_suppress hsa-mir-99a Bladder Neoplasms 24944696 "It was found that miRNA-99a inhibits cell proliferation, migration and invasion in T24 and EJ cells." genetics_overexpression_suppress hsa-mir-34a Glioma 24944883 "Ectopic expression of miR-34a in glioma stem cell-lines HNGC-2 and NSG-K16 decreased the proliferative and migratory potential of these cells, induced cell cycle arrest and caused apoptosis." genetics_overexpression_suppress hsa-mir-146a Ischemia-Reperfusion Injury 24987958 "Overexpression of miR-146a directly decreased IRAK1 and TRAF6 expression and attenuated the release of proinflammatory cytokines through the inactivation of NF-κB P65 in hypoxia/reoxygenation (H/R)-induced macrophages, RAW264.7 cells." genetics_overexpression_suppress hsa-let-7 Pancreatic Neoplasms 25017900 "Sulforaphane, quercetin and catechins complement each other in elimination of advanced pancreatic cancer by miR-let-7 induction and K-ras inhibition." genetics_overexpression_suppress hsa-mir-7 Neurodegenerative Diseases [unspecific] 25071443 "Overexpression of miR-7 or miR-153 by adenoviral transduction protected cortical neurons from MPP(+)-induced toxicity, restored neuronal viability and anti-apoptotic BCL-2 protein levels while attenuated activation of caspase-3." genetics_overexpression_suppress hsa-mir-155 Cerebral Malaria 25189739 AAV8-mediated in vivo overexpression of miR-155 enhances the protective capacity of genetically attenuated malarial parasites. genetics_overexpression_suppress hsa-let-7d "Carcinoma, Renal Cell" 25193015 "Functional studies indicated that ectopic expression of let-7d significantly inhibited RCC cell proliferation, migration, and peripheral blood monocyte (PBMC) recruitment in vitro, as well as tumor growth, metastasis, and tumor macrophage infiltration in vivo." genetics_overexpression_suppress hsa-let-7g Osteosarcoma 25197332 "Functional investigation revealed both restoration of let-7g and silencing Aurora-B induce cell apoptosis and suppressed cell viability, migratory and invasive ability in OS cells." genetics_overexpression_suppress hsa-mir-449a "Carcinoma, Gastric" 25202363 The level of MGC-803 cell proliferation was decreased and the apoptosis level was increased by the upregulation of miR-449a expression genetics_overexpression_suppress hsa-mir-200b Hypertrophic Scar 25228082 Overexpression of miR-200b inhibits the cell proliferation and promotes apoptosis of human hypertrophic scar fibroblasts in vitro. genetics_overexpression_suppress hsa-mir-206 "Squamous Cell Carcinoma, Oral" 25246801 "upregulation of miR-206 in Tca8113 cells was able to reduce cell proliferation, invasion, and migration and promote cell apoptosis in vitro." genetics_overexpression_suppress hsa-mir-200c Lung Neoplasms 25277203 miR-200c overexpression is associated with better efficacy of EGFR-TKIs in non-small cell lung cancer patients with EGFR wild-type. genetics_overexpression_suppress hsa-mir-21 Ischemia-Reperfusion Injury 25322693 miR-21 is endowed with anti-apoptotic properties by suppressing the expression of PDCD4 gene and active caspase 3/8 fragments in the condition of renal IRI. genetics_overexpression_suppress hsa-mir-7 Lung Neoplasms 25334070 "Restoration of miR-7 inhibited 3LL cell proliferation, induced cell apoptosis in vitro and reduced tumorigenicity in vivo." genetics_overexpression_suppress hsa-mir-30b "Carcinoma, Laryngeal" 25356506 Overexpression of microRNA-30b improves adenovirus-mediated p53 cancer gene therapy for laryngeal carcinoma. genetics_overexpression_suppress hsa-mir-218 "Carcinoma, Hepatocellular" 25374061 Overexpression of miR-218 inhibits hepatocellular carcinoma cell growth through RET. genetics_overexpression_suppress hsa-let-7g "Carcinoma, Hepatocellular" 25435961 "the overexpression of let-7g/i significantly suppressed DNA replication, inhibited cell proliferation and promoted apoptosis of BEL-7402 hepatoma cells." genetics_overexpression_suppress hsa-let-7i "Carcinoma, Hepatocellular" 25435961 "the overexpression of let-7g/i significantly suppressed DNA replication, inhibited cell proliferation and promoted apoptosis of BEL-7402 hepatoma cells." genetics_overexpression_suppress hsa-mir-133a Myocardial Infarction 25465869 "miR-133a overexpression protected CPCs against cell death, targeting, among others, the proapoptotic genes Bim and Bmf." genetics_overexpression_suppress hsa-mir-150 Myocardial Infarction 25466411 "In vivo studies showed that overexpression of miR-150 in mice resulted in improved cardiac function, reduced myocardial infarction size, inhibition of apoptosis, and reduced inflammatory Ly-6C(high) monocyte invasion levels after AMI." genetics_overexpression_suppress hsa-let-7b Gastric Neoplasms 25510669 "Ectopic expression of let-7b suppressed the growth, migration, invasion, and tumorigenicity of GC cells, whereas let-7b knockdown promoted these phenotypes." genetics_overexpression_suppress hsa-mir-16 Glioma 25511497 miR-16 can significantly inhibit the in vivo growth of U87MG glioma. genetics_overexpression_suppress hsa-let-7 Gastric Neoplasms 25549793 There were significant negative correlations between serum let-7c and its target gene PGC expression genetics_overexpression_suppress hsa-mir-10a Congenital Diaphragmatic Hernia 25563880 Human fetal hypoplastic CDH lungs have a specific miR-200/miR-10a signature. Survival after FETO is associated with increased miR-200 family expression. miR-200b overexpression in CDH lungs results in decreased TGF-¦Â/SMAD signaling. genetics_overexpression_suppress hsa-mir-200 Congenital Diaphragmatic Hernia 25563880 Human fetal hypoplastic CDH lungs have a specific miR-200/miR-10a signature. Survival after FETO is associated with increased miR-200 family expression. miR-200b overexpression in CDH lungs results in decreased TGF-¦Â/SMAD signaling. genetics_overexpression_suppress hsa-mir-200b Congenital Diaphragmatic Hernia 25563880 Human fetal hypoplastic CDH lungs have a specific miR-200/miR-10a signature. Survival after FETO is associated with increased miR-200 family expression. miR-200b overexpression in CDH lungs results in decreased TGF-¦Â/SMAD signaling. genetics_overexpression_suppress hsa-mir-146b Cervical Neoplasms 25572123 "miRâ€?46bâ€?p was able to inhibit the proliferative, invasive and adhesive potential and block the cell cycle progression of Caski human cervical cancer cells" genetics_overexpression_suppress hsa-mir-143 Osteosarcoma 25576341 Forced miR-143 expression significantly inhibited tumor growth in xenograft SAOS-2-Dox and U2OS-Dox animal models. genetics_overexpression_suppress hsa-let-7b Uveal Melanoma 25588203 We then confirmed that let-7b mimics could inhibit UM growth both in vitro and in vivo. genetics_overexpression_suppress hsa-mir-214 Ischemia-Reperfusion Injury 25593579 Transfection of miR-214 mimic showed protective effects on OGD-induced injury to H9c2 cells by reducing apoptosis genetics_overexpression_suppress hsa-mir-17 Melanoma 25594054 "The melanoma tumors formed in mice overexpressing miR-17 were less than that in wild type mice. In addition, the miR-17 tumors were less invasive and less angiogenic." genetics_overexpression_suppress hsa-let-7 Neoplasms [unspecific] 25597880 let-7 microRNA would be involved in over-expression of cofilin-1 mediated tumor suppression in vitro and in vivo. genetics_overexpression_suppress hsa-mir-30a Hepatitis B Virus Infection 25620738 "HBx induces autophagosome formation via beclin-1 expression, whereas miRNA-30a overexpression could successfully inhibit the beclin-1 expression induced by HBx, thereby modulating autophagosome formation in hepatic cells." genetics_overexpression_suppress hsa-mir-29a Glioblastoma 25625222 "Exogenous miR-29s substantially inhibited the proliferation, migration and invasion of U87MG cells, and promoted their apoptosis." genetics_overexpression_suppress hsa-mir-135a Medulloblastoma 25639612 "Remarkably, enforced expression of miR-135a in HT CSCs strongly inhibited tumorigenesis by repressing the miR-135a direct target gene Arhgef6." genetics_overexpression_suppress hsa-mir-133a Heart Failure 25658461 transfecting MSCs with miR-133a mimic improves survival of MSCs as determined by the MTT assay. genetics_overexpression_suppress hsa-mir-124 Osteosarcoma 25667613 "transfection of miR-124 mimic into MG63 cells was able to reduce cell proliferation, invasion and migration, and promote cell apoptosis." genetics_overexpression_suppress hsa-mir-184 "Carcinoma, Renal Cell" 25667660 "Our studies revealed that miR-184 mimic significantly inhibits cell migration, suppresses cell proliferation and induces renal cancer cell apoptosis in vitro when compared with the negative control (P<0.05)." genetics_overexpression_suppress hsa-mir-16 Breast Neoplasms 25672252 "Overexpression of microRNA-16 declines cellular growth, proliferation and induces apoptosis in human breast cancer cells." genetics_overexpression_suppress hsa-mir-1 "Squamous Cell Carcinoma, Esophageal" 25672418 Downregulation of microRNA-1 in esophageal squamous cell carcinoma correlates with an advanced clinical stage and its overexpression inhibits cell migration and invasion. genetics_overexpression_suppress hsa-mir-150 "Leukemia, Lymphoblastic, Acute" 25687053 "miR-150 may be a putative oncoprotein in T-ALL cells. Overexpression of miR-150 has noticeable effects on the proliferation inhibition and apoptosis induction of Jurkat cells, which may be mediated by the negative regulation of PI3K/Akt /NF-¦ÊB signaling pathway." genetics_overexpression_suppress hsa-mir-21 Immune System Disease [unspecific] 25688245 miR-21 has emerged as a key mediator of the anti-inflammatory response in macrophages. genetics_overexpression_suppress hsa-mir-203 Brain Disease [unspecific] 25723469 enforced expression of miR-203 or MyD88 siRNA silencing inhibits downstream NF-¦Ê¦Â signaling and microglia activation genetics_overexpression_suppress hsa-mir-126 Spinal Cord Injuries 25724143 "increased levels of miR-126 promoted angiogenesis, and inhibited leukocyte extravasation into the injured spinal cord" genetics_overexpression_suppress hsa-let-7f Glioma 25735962 "The enhanced expression of Let-7f suppressed glioma cells proliferation, migration, and invasion via direct targeting perisotin oncogenic activity." genetics_overexpression_suppress hsa-mir-122 Liver Neoplasms 25762642 "miR-107, mir-122, miR-29, miR-365 and miR-802 exhibited weak to moderate tumor suppressor potential." genetics_overexpression_suppress hsa-mir-210 Cerebral Ischemia 25783636 Rats treated with VNS showed increased miR-210 expression as well as decreased apoptosis and antioxidant stress responses compared with the I/R group genetics_overexpression_suppress hsa-mir-29b Prostate Neoplasms 25784815 forced expression of miR-29b inhibited cell proliferation and cell invasion and induced cell apoptosis in PCa. genetics_overexpression_suppress hsa-mir-184 Retinal Neovascularization 25796186 miR-184 mimic inhibits Wnt signaling in the OIR retina genetics_overexpression_suppress hsa-mir-26a Nervous System Diseases [unspecific] 25808510 We found that miR-26a up-regulation promoted neurite outgrowth and reduced apoptosis in bupivacaine-injured DRG neurons. genetics_overexpression_suppress hsa-mir-21 Myocardial Infarction 25809568 "In miR-21 group, myocardial infarct size reduced by 36.9% in comparison with LV-GFP group." genetics_overexpression_suppress hsa-let-7a Breast Neoplasms 25846193 "Cell proliferation, colony formation, migration and invasion were decreased after overexpression of let-7a in breast cancer cells and vice versa." genetics_overexpression_suppress hsa-mir-193b Adenovirus Infection 25854561 The over-expression of miR-193b may suppress the proliferation of K562 cells. genetics_overexpression_suppress hsa-mir-206 Medulloblastoma 25859932 "MiR-206, a Cerebellum Enriched miRNA Is Downregulated in All Medulloblastoma Subgroups and Its Overexpression Is Necessary for Growth Inhibition of Medulloblastoma Cells." genetics_overexpression_suppress hsa-mir-26a Graft-Versus-Host Disease 25865461 The prolonged allograft survival induced by LV-Mir-26a was also completely abrogated by IL-6 overexpression. genetics_overexpression_suppress hsa-let-7a "Carcinoma, Nasopharyngeal" 25884389 "synthetic let-7a mimics suppressed NPC cells migration, invasion and EMT process and knockdown of HMGA2 was consistent with the effects of let-7a in NPC cells." genetics_overexpression_suppress hsa-mir-146a Atherosclerosis 25904598 cellular enrichment of miR-146a through the systemic delivery of miR-146a mimetics in Apoe(-/-)Ldlr(-/-) and Ldlr(-/-) mice attenuated monocyte/macrophage activation and atherosclerosis in the absence of plasma lipid reduction. genetics_overexpression_suppress hsa-mir-145 Malignant Neoplasms [unspecific] 25926306 "cell proliferation level of OS-732 with microRNA-145 overexpression was significantly decreased, and OS-732 cell invasion capacity was also significantly decreased" genetics_overexpression_suppress hsa-mir-145 Prostate Neoplasms 25951106 Overexpression of miR-145-5p inhibits proliferation of prostate cancer cells and reduces SOX2 expression. genetics_overexpression_suppress hsa-mir-133a Heart Failure 25960234 The miR-133a mimic and miR-133a overexpression significantly caused a decrease in the fibrosis of heart in chronic heart failure rats. genetics_overexpression_suppress hsa-mir-138 "Carcinoma, Gallbladder" 25962180 Expression of miR-138 is frequently reduced in gallbladder carcinoma when compared to normal cells. Overexpression of miR-138 inhibited cell proliferation by directly suppressing the expression of Bag-1. These results suggest that miR-138 plays an important role in inhibiting the growth of gallbladder carcinoma. genetics_overexpression_suppress hsa-mir-95 "Adenocarcinoma, Lung" 25971210 Overexpression of microRNA-95-3p suppresses brain metastasis of lung adenocarcinoma through downregulation of cyclin D1. genetics_overexpression_suppress hsa-mir-202 Multiple Myeloma 25971527 The growth rate of miR-202 mimics transfection cells was significantly lower than that of non-transfected cells. genetics_overexpression_suppress hsa-mir-133a Vascular Hypertrophy 25995211 delivery of miR-1 and miR-133a suppressed inducible cAMP early repressor expression and prevented both electrical remodeling and hypertrophy. genetics_overexpression_suppress hsa-mir-100 Osteosarcoma 26018508 Overexpression of miR-100 inhibits growth of osteosarcoma through FGFR3. genetics_overexpression_suppress hsa-mir-214 Ischemia-Reperfusion Injury 26025394 214 may participate in the protective function of ischemic post conditioning by down regulating HIF1AN. genetics_overexpression_suppress hsa-mir-16 Sarcoma [unspecific] 26044957 "miR-16, but not other downregulated miRNAs, was able to significantly suppress both migration and invasion in vitro" genetics_overexpression_suppress hsa-mir-146a Sepsis 26048146 In vivo transfection of LmiR-146a attenuated sepsis-induced cardiac dysfunction. genetics_overexpression_suppress hsa-mir-506 Breast Neoplasms 26059632 "MiR-506 over-expression significantly inhibits the proliferation,colony formation, and migration of breast cancer cells. miR-506 over-expression may thus be able to improve the malignant phenotype of breast cancer cells." genetics_overexpression_suppress hsa-mir-16 "Adenocarcinoma, Lung" 26064212 enforced expression of mir-16 lead to reduced A549 cell proliferation and promote apoptosis. genetics_overexpression_suppress hsa-mir-195 Colorectal Carcinoma 26064276 has-miR-195 can promote cell apoptosis and inhibit the invasion and metastasis by inhibiting the expression of Bcl-2. genetics_overexpression_suppress hsa-mir-98 Neuroinflammation 26126865 "Overexpression of let-7 and miR-98 in vitro and in vivo resulted in reduced leukocyte adhesion to and migration across endothelium, diminished expression of pro-inflammatory cytokines, and increased BBB tightness, attenuating barrier 'leakiness' in neuroinflammation conditions." genetics_overexpression_suppress hsa-mir-138 Cardiovascular Diseases [unspecific] 26129883 over-expression of miR-138 significantly enhanced the cell growth and significantly attenuated the cell apoptosis in hypoxic conditions. genetics_overexpression_suppress hsa-mir-29a Prostate Neoplasms 26131109 "enforced expression of miR-29a in PC-3 and LNCaP cells inhibited proliferation, and induced apoptosis by repressing the expression of KDM5B." genetics_overexpression_suppress hsa-mir-146a Sepsis 26138422 "Up-regulation of miR-146a inhibit the release of the inflammatory cytokine TNF-α stimulated by sepsis, and alleviate inflammatory reaction and lung tissue injury in mice with sepsis-induced ALI." genetics_overexpression_suppress hsa-mir-27b Cardiovascular Diseases [unspecific] 26161255 miR-27b mimic had overall beneficial effects genetics_overexpression_suppress hsa-mir-573 Rheumatoid Arthritis 26166764 miR-573 overexpression suppressed the expression of interleukin 6 (IL-6) and cyclooxygenase 2 in RASFs genetics_overexpression_suppress hsa-mir-137 Melanoma 26186482 overexpression of miR-137 inhibited the proliferation of melanoma cells genetics_overexpression_suppress hsa-mir-34c Diabetic Nephropathy 26191142 miR-34c was downregulated and that overexpression of miR-34c inhibited HG-induced podocyte apoptosis. genetics_overexpression_suppress hsa-mir-221 Astrocytoma 26191177 Overexpression of miR-221 inhibits proliferation and promotes apoptosis of human astrocytoma cells. genetics_overexpression_suppress hsa-mir-23b Neoplasms [unspecific] 26198058 "miR-23b, miR-199a, and miR-15a displayed increased expression during early AVC development whereas others such as miR-130a and miR-200a display decreased expression levels" genetics_overexpression_suppress hsa-mir-26a "Diabetes Mellitus, Type 2" 26208605 Mir-26a suppresses autoimmune diabetes in NOD mice in part through promoted regulatory T cells (Tregs) expression. genetics_overexpression_suppress hsa-mir-140 Osteosarcoma 26219893 "relative miR-140 expression was increased, cell proliferation was inhibited, cell population in G0/G1 phase was increased, cell population in G2/M phase and S phases and proliferation index (PI), and cell migration distance were decreased in the miR-140 mimic group" genetics_overexpression_suppress hsa-mir-210 Osteoarthritis 26244598 "Transfection with miR-210 mimic inhibited LPS-induced pro-inflammatory cytokines production, cell viability reduction and cell apoptosis." genetics_overexpression_suppress hsa-mir-1 Vascular Hypertrophy 26253469 the administration of a miR-1 mimic attenuated cardiac hypertrophy by suppressing the transverse aortic constriction-induced increase in myocardin expression genetics_overexpression_suppress hsa-mir-302b "Carcinoma, Hepatocellular" 26254095 Overexpression of miR-302b suppressed HCC cell invasion and metastasis. genetics_overexpression_suppress hsa-mir-143 Prostate Neoplasms 26269764 "miR-143 has an inhibitory effect on cell proliferation as evidenced by decreased cell viability, increased cell apoptosis and cell cycle arrest at the G1/S transition." genetics_overexpression_suppress hsa-mir-125a Colon Neoplasms 26297542 overexpression of miR-125a-5p inhibited cell proliferation and induced cell apoptosis in colon cancer cells. genetics_overexpression_suppress hsa-mir-31 "Adenocarcinoma, Lung" 26299665 overexpression of miR-31 led to the inhibition of adenocarcinoma cell proliferation. genetics_overexpression_suppress hsa-mir-206 "Carcinoma, Lung, Non-Small-Cell" 26309565 "Forced overexpression of miR-206 significantly inhibited cell proliferation, migration and invasion of NSCLC cells." genetics_overexpression_suppress hsa-mir-26a Ischemia-Reperfusion Injury 26320674 Mir-26a overexpression results in attenuated cardiac IR injury and inhibited HMGB1 expression. genetics_overexpression_suppress hsa-mir-33b Colorectal Carcinoma 26329295 miR-33b inhibited tumor cell growth and induced cell cycle arrest. genetics_overexpression_suppress hsa-mir-9 Inflammation 26354749 "miR-9 overexpression significantly repressed NF-κB expression and, thereby, suppressed inflammation but promoted LEC tube formation" genetics_overexpression_suppress hsa-mir-9 Spinal Cord Injuries 26359086 miR-9 overexpression promoted osteoblast differentiation and angiogenesis genetics_overexpression_suppress hsa-mir-634 Cervical Neoplasms 26367112 "miR-634 inhibited cell proliferation, migration and invasiveness in cervical cancer cells and the block of miR-634 enhances the mTOR expression at both the mRNA and protein levels which regulated the expression of mTOR negatively." genetics_overexpression_suppress hsa-mir-16 Glioblastoma 26373393 "Overexpression of microRNA- 16 in the A172 and U87 GBM cell lines inhibited the activities of co-cultured endothelial cells, including proliferation, migration, extension and tubule formation." genetics_overexpression_suppress hsa-mir-145 Glioblastoma 26374689 "CSCs expressed low levels of miR-145, and its introduction decreased self-renewal through reductions in AKT signaling and stem cell marker (SOX2, OCT4, and NANOG) expression" genetics_overexpression_suppress hsa-mir-449a Liver Neoplasms 26375440 "Overexpression of miR-449a inhibited cell proliferation, induced G1 phase arrest and cell apoptosis in liver cancer." genetics_overexpression_suppress hsa-mir-1 Myocardial Infarction 26380976 miR-1 and -21 jointly blocked hypoxia-induced cardiomyocytes apoptosis. genetics_overexpression_suppress hsa-mir-21 Myocardial Infarction 26380976 miR-1 and -21 jointly blocked hypoxia-induced cardiomyocytes apoptosis. genetics_overexpression_suppress hsa-mir-16 "Carcinoma, Nasopharyngeal" 26383521 "we identified upregulation of tumor suppressor miR-16a, which inhibited cell cycle progression and sensitized NPC cells to chemotherapy." genetics_overexpression_suppress hsa-mir-221 Ischemia-Reperfusion Injury 26396139 "Mimics of miRNA-221, -150, and -206 were protective in both H9c2 and NRVM." genetics_overexpression_suppress hsa-mir-133a "Cardiomyopathy, Hypertrophic" 26403739 miR-133a is an important regulator of phenylephrine-induced cardiomyocyte hypertrophy and negatively regulates this process. genetics_overexpression_suppress hsa-mir-7 Adrenal Cortex Neoplasms 26452132 microRNA-7-5p (miR-7) reduces cell proliferation in vitro and induces G1 cell cycle arrest. genetics_overexpression_suppress hsa-mir-125b Cholangiocarcinoma 26455324 "We also found that enforced expression of let-7c, miR-99a or miR-125b could reduce the activity of STAT3 and further suppress CCA tumorigenicity in vivo and inhibit the migration and invasion of CCA cells in vitro." genetics_overexpression_suppress hsa-mir-34a Alzheimer Disease 26459758 "Importantly, the overexpression of TAp73α and miR-34a reversed cell cycle-related neuronal apoptosis (CRNA)." genetics_overexpression_suppress hsa-mir-140 Rheumatoid Arthritis 26473405 "Overexpression of miRNAs 140-3p and 140-5p caused a reduction in expression, with correlated kinetic patterns, of their corresponding target molecules sirtuin 1 and stromal cell-derived factor 1 in the SFs and joints of mice." genetics_overexpression_suppress hsa-mir-29a "Carcinoma, Thyroid, Papillary" 26482618 "overexpression of miR-29a markedly suppressed PTC cell proliferation, migration, and invasion and promoted PTC apoptosis and cell cycle arrest at G0/G1 phase." genetics_overexpression_suppress hsa-mir-29c "Carcinoma, Embryonal" 26484393 MicroRNA-29c overexpression inhibits proliferation and promotes apoptosis and differentiation in P19 embryonal carcinoma cells. genetics_overexpression_suppress hsa-mir-26a "Carcinoma, Lung, Non-Small-Cell" 26492332 "Overexpression of miR-26a in A549 cells inhibited G1-S transition, increased cell death in response to CDDP treatment, and decreased the colony formation of A549 cells." genetics_overexpression_suppress hsa-mir-214 "Carcinoma, Hepatocellular" 26498144 Overexpression of miR-214 in HCC cells inhibited proliferation by inducing G1-S checkpoint arrest. genetics_overexpression_suppress hsa-mir-138 Laryngeal Neoplasms 26499780 "miR-138 overexpression inhibited ZEB2-mediated cell invasiveness, while miR-138 depletion increased ZEB2-mediated cell invasiveness in LC cells." genetics_overexpression_suppress hsa-mir-16 "Carcinoma, Hepatocellular" 26499886 "The results of this study suggest that the overexpression of miR-16 inhibits the proliferation, invasion and metastasis of HepG2 HCC cells, and that these effects are associated with the PI3K/Akt signaling pathway." genetics_overexpression_suppress hsa-mir-152 Cervical Neoplasms 26515145 Overexpression of miR-152 repressed WNT1 and ERBB3 expression and decreased proliferation of HeLa cells. genetics_overexpression_suppress hsa-mir-222 "Squamous Cell Carcinoma, Tongue" 26517090 "Moreover, miR-222 mimics and ABCG2 siRNA inhibited tumor growth and lung metastasis in vivo." genetics_overexpression_suppress hsa-mir-449a Prostate Neoplasms 26520443 "Overexpression of miR-449a induces cell cycle arrest, apoptosis, and senescence" genetics_overexpression_suppress hsa-mir-205 "Carcinoma, Skin" 26527515 "Ectopic expression of miR-205-5p in spindle cancer cells reduces Rap1a, mitigates cell invasiveness, decreases proliferation, and delays tumor onset." genetics_overexpression_suppress hsa-mir-195 Thyroid Neoplasms 26527888 exogenous overexpression of miR-195 significantly inhibits the protein expression of Raf1 and blocks the thyroid cancer cell proliferation. genetics_overexpression_suppress hsa-let-7b Myocardial Ischemic-Reperfusion Injury 26542107 intramyocardial injection of let-7b-modified MSCs significantly enhanced ventricular function and facilitated myocardial repair by protecting transplanted cells from apoptosis and autophagy in the rat cardiac ischemia-reperfusion model. genetics_overexpression_suppress hsa-mir-363 Head And Neck Neoplasms 26545583 "These findings demonstrate that the overexpression of miR-363 reduces cellular migration in head and neck cancer and reveal the biological relationship between miR-363, myosin 1b, and HPV-positive SCCHN." genetics_overexpression_suppress hsa-mir-150 Osteosarcoma 26561465 "restoration of miR-150 expression in OS cells could inhibit cell proliferation, migration, and invasion and induced apoptosis in vitro as well as suppressed tumor growth of OS in vivo." genetics_overexpression_suppress hsa-mir-7-1 Glioblastoma 26573275 "In conclusion, our results clearly demonstrated that overexpression of miR-7-1-3p augmented the anti-tumor activities of LUT and SIL to inhibit autophagy and induce apoptosis for controlling growth of different human glioblastomas in vivo." genetics_overexpression_suppress hsa-mir-15a "Carcinoma, Hepatocellular" 26581909 "Ectopic overexpression of miR-15a-5p suppressed cancer proliferation, induced cell cycle arrest in HepG2 or SNU-182 cells in vitro, and inhibited HCC tumor growth in vivo." genetics_overexpression_suppress hsa-mir-16 Alzheimer Disease 26592823 Overexpression and inhibition of miR-16 in the cellular AD model with primary hippocampal neurons decreased and increased apoptosis genetics_overexpression_suppress hsa-mir-125b Melanoma 26596831 Restored expression of miR-125b in melanoma suppressed cell proliferation and invasion both in vitro and in vivo. genetics_overexpression_suppress hsa-mir-100 Ovarian Neoplasms 26607088 The expression of miR-100 is downregulated in SKOV3/DDP cells.Overexpressing miR-100 may effectively increase the sensitivity to cisplatin of human ovarian epithelial cancer SKOV3/DDP cells and may reverse cisplatin-resistance of EOC (epithelial ovarian cancer). genetics_overexpression_suppress hsa-mir-145 "Carcinoma, Hepatocellular" 26615424 "Overexpression of miR-145 in HCC cell lines significantly inhibited cell proliferation, migration, and invasion in vitro." genetics_overexpression_suppress hsa-mir-143 Breast Neoplasms 26618772 "Up-regulating miR-143 enhanced E-cadherin-mediated cell-cell adhesion ability, reduced mesenchymal markers, and decreased cell proliferation, migration, and invasion in vitro." genetics_overexpression_suppress hsa-mir-18a "Carcinoma, Gastric" 26622381 The results showed that miR-18a overexpression was able to promote cell apoptosis and inhibit cell invasion. genetics_overexpression_suppress hsa-mir-182 Glioma 26622652 "overexpression of miR-182 affected cell cycle regulation and cell migration capacity in vitro, which may have been associated with the promotion of apoptosis by this molecule." genetics_overexpression_suppress hsa-mir-195 Cervical Neoplasms 26622903 "The expression of miR-195 mimics in the cervical cancer HeLa cell line significantly decreased the cell proliferation, migration and invasion capacities in vitro." genetics_overexpression_suppress hsa-mir-302b Breast Neoplasms 26623722 "miR-302b overexpression enhances sensitivity to cisplatin in breast cancer cell lines, reducing cell viability and proliferation in response to the treatment." genetics_overexpression_suppress hsa-mir-195 Cervical Neoplasms 26631043 overexpression of miR-195 played a suppressor role in the proliferation of HeLa and SiHa cells and promoted cell apoptosis. genetics_overexpression_suppress hsa-mir-195 Breast Neoplasms 26632252 "ectopic expression of hsa-miR-195 in MCF-7 and MDA-MB-231 cells not only altered cellular cholesterol and triglyceride levels significantly but also resulted in reduced proliferation, invasion and migration." genetics_overexpression_suppress hsa-mir-1 Cardiomegaly 26638879 miRNA-1 overexpression prevented cardiomyocyte hypertrophy. genetics_overexpression_suppress hsa-mir-16 "Lymphoma, Non-Hodgkin" 26640145 The miR-16 transfection significantly decreased senescent cells and increased apoptotic cells genetics_overexpression_suppress hsa-mir-16 "Lymphoma, T-Cell, Cutaneous" 26640145 The miR-16 transfection significantly decreased senescent cells and increased apoptotic cells genetics_overexpression_suppress hsa-mir-16 "Carcinoma, Nasopharyngeal" 26655091 "Ectopic expression of miR-16 suppressed NPC cell proliferation, migration, and invasion in vitro and inhibited tumor growth and metastatic colonization in the lung in vivo." genetics_overexpression_suppress hsa-mir-372 "Carcinoma, Endometrial" 26673619 miR-372 overexpression suppressed tumor growth genetics_overexpression_suppress hsa-mir-222 Osteoarthritis 26673737 Over-expression of miR-222 significantly suppressed apoptotic death by down-regulating HDAC-4 and MMP-13 level. genetics_overexpression_suppress hsa-mir-30a "Carcinoma, Ovarian" 26675258 "Overexpression of miR-30a decreased Akt and mitogen activated protein kinase signaling pathway activation, cell proliferation, invasion, plasticity, EMT marker levels, and vascular endothelial growth factor release." genetics_overexpression_suppress hsa-mir-215 Ovarian Neoplasms 26676658 "Upregulation of miR-215 inhibited cell proliferation, promoted apoptosis and increased sensitivity to chemotherapy drugs in EOC cells." genetics_overexpression_suppress hsa-mir-192 "Carcinoma, Hepatocellular" 26684241 miR-192 significantly suppressed metastasis of HCC cells in vitro and in vivo. genetics_overexpression_suppress hsa-mir-181d "Squamous Cell Carcinoma, Oral" 26693182 Ectopic expression of miR-181a/d decreased anchorage independent growth and CSC phenotype of HPV16-transfected OSCC. genetics_overexpression_suppress hsa-mir-494 "Carcinoma, Ovarian" 26695144 "overexpression of miR-494 in EOC cells could remarkably inhibit proliferation, colony formation, migration, and invasion and induce cell apoptosis, G0/G1 phase arrest." genetics_overexpression_suppress hsa-mir-1 "Cardiomyopathy, Hypertrophic" 26699910 "miR-1 mimic, in parallel to CDK6 siRNA, could inhibit PE-induced hypertrophy of NRVCs, with decreases in cell size" genetics_overexpression_suppress hsa-mir-148a Breast Neoplasms 26707142 The ectopic miR-148a expression inhibited the migration and invasion of MCF-7 and MDA-MB-231 breast cancer cells. genetics_overexpression_suppress hsa-mir-145 Breast Neoplasms 26715279 "Overexpression of miR-145 in MCF-7 and BT-549 cell lines significantly inhibited cell proliferation, migration, and invasion in vitro." genetics_overexpression_suppress hsa-mir-206 "Carcinoma, Renal Cell, Clear-Cell" 26718123 "upregulation of miR-206 inhibited renal cancer cell proliferation, invasion and migration" genetics_overexpression_suppress hsa-mir-452 "Carcinoma, Lung, Non-Small-Cell" 26718215 "xpression of miR-452 via adenoviral (Ad) vector inhibits the proliferation, invasion, and migration of NSCLC cells A549 or H460." genetics_overexpression_suppress hsa-mir-143 Prostate Neoplasms 26721309 miR-143 restoration decreased secreted MMP-2 and MMP-9 enzyme activities compared with scramble controls genetics_overexpression_suppress hsa-mir-34c "Carcinoma, Hepatocellular, HBV-Related" 26722295 "The restoration of miR-34c in HepG2.2.15 cells suppressed TGIF2 expression, HBV replication and viral antigen synthesis; inhibited cell proliferation; and induced apoptosis." genetics_overexpression_suppress hsa-mir-34a Prostate Neoplasms 26722316 The over-expression of miR-34a inhibited PC-3 cells growth and resulted in increased cell cycle arrest compared with the negative control (P<0.05). genetics_overexpression_suppress hsa-mir-145 "Carcinoma, Breast, Triple Negative" 26733177 tumor necrosis factor-alpha (TNF-α)-induced apoptosis was expanded by the transfection of miR-145 in MDA-MB-231 which belongs to the TNBC cell lines. genetics_overexpression_suppress hsa-mir-488 Gastric Neoplasms 26738864 "The ectopic expression of miR-488 suppressed the GC cell proliferation, cell cycle, colony information, and migration." genetics_overexpression_suppress hsa-mir-125b Osteosarcoma 26744308 "stable overexpression of miR-125b in osteosarcoma cell lines U2OS and MG-63 inhibited cell proliferation, migration, and invasion." genetics_overexpression_suppress hsa-let-7 Gastric Neoplasms 26745603 "overexpression of miR-let-7a markedly suppressed the proliferation, migration, and invasion of GC cells by down-regulating the expression of PKM2." genetics_overexpression_suppress hsa-mir-23b Asthma 26748386 Overexpression of miR-23b significantly inhibited TGF-β1-induced ASMCs proliferation and promoted apoptosis. genetics_overexpression_suppress hsa-mir-378 Breast Neoplasms 26749280 "ectopic expression of miR-378 in MDA-MB-231 cells inhibited Runx1 and suppressed migration and invasion, while inhibition of miR-378 in MCF7 cells increased Runx1 levels and cell migration." genetics_overexpression_suppress hsa-let-7f Glioma 26750768 inhibiting the pro-migratory function of POSTN by the overexpression of miR-Let-7f significantly reduced the formation of VM. genetics_overexpression_suppress hsa-mir-320 Cervical Neoplasms 26753959 "miR-320 induces apoptosis via down-regulation of Mcl-1 and activation of caspase-3 but inhibits cell proliferation, migration, invasion, and tumorigenesis in cervical cancer cells." genetics_overexpression_suppress hsa-mir-340 Breast Neoplasms 26758430 miR-340 could dramatically down-regulate metastasis by targeting Wnt signaling in breast cancer cells. genetics_overexpression_suppress hsa-mir-143 "Squamous Cell Carcinoma, Esophageal" 26758433 "miR-143 exerted a tumor-suppressing effect by inhibiting the proliferation, migration, and invasion and inducing G1/G0 phase arrest of ESCC cells via the negative regulation of FAM83F expression." genetics_overexpression_suppress hsa-mir-381 Ovarian Neoplasms 26768613 "Overexpression of miR-381 significantly inhibited EOC cell proliferation, migration, and invasion." genetics_overexpression_suppress hsa-mir-503 Osteosarcoma 26768615 miR-503 overexpression suppressed cell invasion and migration and inhibited epithelial-to-mesenchymal transition (EMT) of MG-63. genetics_overexpression_suppress hsa-mir-29a Multiple Myeloma 26771839 "In addition, ectopic expression of miRNA-29a or exposure to PRIMA-1Met reduced cell proliferation and induced apoptosis in MM cells." genetics_overexpression_suppress hsa-mir-30a "Carcinoma, Urothelial" 26775686 Both miR-30a and small interfering RNA Notch1 negatively regulated cell proliferation genetics_overexpression_suppress hsa-mir-210 Hypoxia 26780211 miR-210 upregulation exerted amelioration on the hypoxia-induced apoptosis genetics_overexpression_suppress hsa-mir-27b Gastric Neoplasms 26780940 miR-27b overexpression significantly inhibited H. pylori infection-induced cell proliferation and WNT signaling pathway activation in gastric cancer cells. genetics_overexpression_suppress hsa-mir-20a "Squamous Cell Carcinoma, Oral" 26781875 "Upregulation of miR-20a by transfected plasmid HPV-16 E7 can significantly inhibit Cal27 cell proliferation, invasion, and migration." genetics_overexpression_suppress hsa-mir-214 "Carcinoma, Hepatocellular" 26788207 enhanced expression of miR-214 or silencing of E2F3 inhibited the proliferation of HCC SMMC-7721 cells. genetics_overexpression_suppress hsa-mir-382 Colorectal Carcinoma 26800338 "Transfection with miR-382 mimics impeded the growth, migration, and invasion of CRC cells." genetics_overexpression_suppress hsa-mir-125b Bladder Neoplasms 26807182 "Overexpression of miR-125b inhibited cellular growth, suppressed cellular migration and caused an accumulation of cells in the G1 phase of the cell cycle" genetics_overexpression_suppress hsa-mir-152 Colorectal Carcinoma 26820128 restoring the expression of miR-152 in CRC cells dramatically reduced the cell proliferation and cell migration and invasion and promoted apoptosis genetics_overexpression_suppress hsa-mir-451 Rheumatoid Arthritis 26823778 miR-451 treatment significantly decreased cell proliferation ability genetics_overexpression_suppress hsa-mir-30a "Adenocarcinoma, Lung" 26837415 overexpression of miR-30a in A549 cells inhibited migration and invasion but not cell proliferation and cell cycle progression genetics_overexpression_suppress hsa-mir-137 Gastric Neoplasms 26840256 Overexpression of miR-9 and miR-137 downregulated the CUL4A-LATS1-Hippo signaling pathway and suppressed GC cell proliferation and invasion in vitro. genetics_overexpression_suppress hsa-mir-9 Gastric Neoplasms 26840256 Overexpression of miR-9 and miR-137 downregulated the CUL4A-LATS1-Hippo signaling pathway and suppressed GC cell proliferation and invasion in vitro. genetics_overexpression_suppress hsa-mir-21 Ischemia 26841045 over-expressing miR-21 in UCBMSCs could improve neovascularization in CLI genetics_overexpression_suppress hsa-mir-448 Gastric Neoplasms 26852749 "Ectopic expression of miR-448 suppressed GC cell proliferation, colony formation, and invasion." genetics_overexpression_suppress hsa-mir-200b Endometriosis 26854065 "up-regulation of miR-200b reverts EMT, emerging as a potential therapeutic approach to inhibit endometriotic cell motility and invasiveness." genetics_overexpression_suppress hsa-mir-373 Glioma 26858153 "although miR-373 does not affect cell growth of U251, it inhibits migration and invasion of U251." genetics_overexpression_suppress hsa-mir-144 "Lymphoma, Large B-Cell" 26865454 "forced expression of miR-144 significantly attenuated cell proliferation and invasion of OCI-Ly3 cells in vitro, and the tumor-suppressor effect of miR-144 was also confirmed using a xenograft mouse model in vivo Taken together" genetics_overexpression_suppress hsa-mir-150 "Carcinoma, Hepatocellular" 26871477 "miR-150 overexpression inhibited cell proliferation, migration and invasion in vitro and tumor growth and metastasis in vivo." genetics_overexpression_suppress hsa-mir-19a Lung Fibrosis 26873752 "intratracheal application of miR-19a, -19b, and 26b reduced the pulmonary fibrotic severity induced by bleomycin" genetics_overexpression_suppress hsa-mir-19b Lung Fibrosis 26873752 "intratracheal application of miR-19a, -19b, and 26b reduced the pulmonary fibrotic severity induced by bleomycin" genetics_overexpression_suppress hsa-mir-26b Lung Fibrosis 26873752 "intratracheal application of miR-19a, -19b, and 26b reduced the pulmonary fibrotic severity induced by bleomycin" genetics_overexpression_suppress hsa-mir-223 Breast Neoplasms 26876200 both RT-induced miR-223 and peri-operative inhibition of EGFR efficiently prevented BC cell growth and reduced recurrence formation in mouse models of BC. genetics_overexpression_suppress hsa-mir-203 "Squamous Cell Carcinoma, Head and Neck" 26882562 "oreover, ectopic overexpression of miR-203 suppressed the invasion and induced mesenchymal-epithelial transition (MET) in HNSCC cells." genetics_overexpression_suppress hsa-mir-451 "Carcinoma, Renal Cell" 26884830 "microRNA-451 inhibited proliferation, migration and invasion of renal cell carcinomas cells." genetics_overexpression_suppress hsa-mir-15b Liver Neoplasms 26884837 MiR-15b mimic transfection promoted miR-15b overexpression and inhibited HepG2 cell proliferation significantly genetics_overexpression_suppress hsa-mir-26b "Carcinoma, Hepatocellular" 26891666 miR-26b-5p inhibited HCC cell growth and impaired the tube formation ability of the HCC cells genetics_overexpression_suppress hsa-mir-15a Gastric Neoplasms 26894855 ectopic expression of miR-15a decreased Bmi-1 in gastric cancer cell lines with reduced proliferation and tumor invasion. genetics_overexpression_suppress hsa-mir-23b Prostate Neoplasms 26898757 miR-23b/-27b expression in prostate cancer cells decreased seminal vesicle invasion and distant metastases genetics_overexpression_suppress hsa-mir-27b Prostate Neoplasms 26898757 miR-23b/-27b expression in prostate cancer cells decreased seminal vesicle invasion and distant metastases genetics_overexpression_suppress hsa-mir-99a Cardiovascular Diseases [unspecific] 26914935 Overexpression of microRNA-99a Attenuates Cardiac Hypertrophy. genetics_overexpression_suppress hsa-mir-146a Glioblastoma 26916895 The upregulation of miR-146a in glioma cells through miR-146a mimic transfection led to reduction of cell viability and to an increase in the percentage of apoptosis. genetics_overexpression_suppress hsa-mir-19b Myocardial Ischemic-Reperfusion Injury 26918829 we found that overexpression of miR-19b decreased H2O2-induced apoptosis and improved cell survival genetics_overexpression_suppress hsa-mir-200b "Carcinoma, Hepatocellular" 26919246 "Forced expression of microRNA-200b in HCC cells dramatically repressed proliferation, colony formation, cell cycle progression, and invasion." genetics_overexpression_suppress hsa-mir-24 "Carcinoma, Nasopharyngeal" 26922862 cell proliferation was suppressed and radiosensitivity increased when miR-24 was ectopically expressed in NPC cells. genetics_overexpression_suppress hsa-mir-34b Osteosarcoma 26924291 Upregulation of miR-34b also induced apoptosis and increased the sensitivity of the cells to the anticancer drugs genetics_overexpression_suppress hsa-mir-372 Gastric Neoplasms 26928593 inhibit proliferations of adenocarcinoma gastric cancer (AGS) cells overexpressing these miRNAs genetics_overexpression_suppress hsa-mir-27a Endometrial Neoplasms 26934121 Enforced expression of miR-124 suppresses EC cell invasion and proliferation. genetics_overexpression_suppress hsa-mir-204 "Carcinoma, Lung, Non-Small-Cell" 26935060 "Transient over-expression of miR-204 by transfecting with miR-204 mimics suppressed NSCLC cell proliferation, migration, and induced apoptosis and G1 arrest" genetics_overexpression_suppress hsa-mir-200b "Carcinoma, Cervical" 26935156 miRâ€?00b suppressed the migratory potential of cervical carcinoma cells genetics_overexpression_suppress hsa-mir-200c "Carcinoma, Lung, Non-Small-Cell" 26935975 Overexpression of miRâ€?00c significantly suppressed cell migration and invasion of A549 NSCLC cells. genetics_overexpression_suppress hsa-mir-141 Neuroblastoma 26936280 "lentivirus-induced miR-141 upregulation inhibited cancer proliferation, cell cycle progression, migration and increased cisplatin chemosensitivity in vitro." genetics_overexpression_suppress hsa-mir-181a "Lymphoma, Large B-Cell" 26941399 "miR-181a decreases DLBCL tumor cell proliferation and survival, and anti-miR-181a abrogates these effects." genetics_overexpression_suppress hsa-mir-21 Acute Myocardial Infarction 26978580 combination of miR-21 and miR-146a has a greater protective effect against cardiac ischemia/hypoxia-induced apoptosis genetics_overexpression_suppress hsa-mir-1 Colorectal Carcinoma 26980745 The ectopic expression of these miRs induced growth suppression and autophagic cell death genetics_overexpression_suppress hsa-mir-200b "Carcinoma, Hepatocellular" 26986232 "Upregulated miRâ€?00b expression in HepG2 cells led to a decrease in DNMT3a expression levels, and an inhibition of cell proliferation." genetics_overexpression_suppress hsa-mir-508 Glioma 27003587 over-expression of miR-508-5p was found to decrease glioma cell growth. genetics_overexpression_suppress hsa-mir-7 Parkinson Disease 27003614 The upregulation of miR-7 promoted cell viability and suppressed cell apoptosis in MPP(+)-treated SH-SY5Y cells. genetics_overexpression_suppress hsa-mir-182 Ischemic Diseases [unspecific] 27008992 Both exogenous miR-182 and Kenpaullone significantly suppressed hypoxia-induced cardiomyocyte death in vitro. genetics_overexpression_suppress hsa-mir-134 Glioma 27012554 upregulated miR-134 expression restrained the proliferation and invasion of U251 cells in vitro. genetics_overexpression_suppress hsa-mir-154 Glioblastoma 27013470 overexpression of miR-154 suppressed cell migration and invasion of U87 and U251 cells. genetics_overexpression_suppress hsa-mir-20a Liver Diseases [unspecific] 27019188 miR-20a-5p mimic could reverse high glucose-induced impaired glycogenesis and AKT/GSK activation in NCTC1469 and Hep1-6 cells. genetics_overexpression_suppress hsa-mir-490 Colorectal Carcinoma 27037061 miR-490-3p suppresses cancer cell proliferation by inducing apoptosis genetics_overexpression_suppress hsa-let-7 "Carcinoma, Salivary Adenoid Cystic" 27042128 "the overexpression of miR-98 in ACC-M cells inhibited cell proliferation, invasion, and migration in vitro." genetics_overexpression_suppress hsa-mir-130b Ovarian Neoplasms 27048832 overexpression of miR-130b reduced the expression of RUNX3 and inhibited cancer cell migration and invasion of EOC cells genetics_overexpression_suppress hsa-mir-206 Muscle Atrophy 27054781 Injection of miR-206 (30 μg/rat) attenuated morphological and physiological deterioration of muscle characteristics genetics_overexpression_suppress hsa-mir-429 Bladder Neoplasms 27058893 Exogenous mimic of miR-429 treatment dramatically inhibited the migratory ability of T24 cells. genetics_overexpression_suppress hsa-mir-221 Neuropathic Pain 27059231 "Intrathecal injection of a miR-221 inhibitor attenuated CCI-induced mechanical allodynia and thermal hyperalgesia, and reduced proinflammatory cytokine expression" genetics_overexpression_suppress hsa-mir-29a Endomyocardial Fibrosis 27060017 over-expression of miRNA-29a suppresses cardiac fibroblasts proliferation. genetics_overexpression_suppress hsa-mir-506 Pancreatic Neoplasms 27065335 "miR-506 inhibited cell proliferation, induced cell cycle arrest at the G1/S transition and enhanced apoptosis and chemosensitivity of pancreatic cancer cells." genetics_overexpression_suppress hsa-mir-101 Osteosarcoma 27073439 "Independent inhibition of c-FOS and overexpression of miR-101 expression levels significantly suppressed U2OS cell proliferation, migration and invasion (P<0.01)." genetics_overexpression_suppress hsa-mir-124 "Carcinoma, Lung, Non-Small-Cell" 27073840 Overexpression of miR-124 apparently suppressed the proliferation and invasion of NSCLC cell lines in vitro. genetics_overexpression_suppress hsa-mir-154 Prostate Neoplasms 27074041 "The forced expression of miR-154-5p or E2F5 knockdown significantly restrained cell growth, as well as the migratory and invasive capabilities." genetics_overexpression_suppress hsa-mir-502 Breast Neoplasms 27080302 "Treatment with miR-502 or downregulation of SET8 suppressed cell proliferation and cell cycle, and reduced cell migration, invasion and EMT." genetics_overexpression_suppress hsa-mir-15b Glioma 27082313 "Furthermore, miRâ€?5b inhibited proliferation and invasion, and promoted apoptosis of glioma cells while downregulating the expression of MMPâ€? and MMPâ€?." genetics_overexpression_suppress hsa-mir-199a Breast Neoplasms 27094578 "Overexpression of miR-199a-5p reduced the mRNA and protein levels of Ets-1 in MCF-7 and MDA-MB-231 cells, whereas anti-miR-199a-5p elevated Ets-1." genetics_overexpression_suppress hsa-mir-125a Retinoblastoma 27094723 The overexpression of miR-125a-5p significantly suppressed cell proliferation and tumor formation in retinoblastoma. genetics_overexpression_suppress hsa-mir-138 Osteosarcoma 27095063 "miR-138 inhibited cell proliferation and invasion, and promoted cell apoptosis of human osteosarcoma cells." genetics_overexpression_suppress hsa-mir-542 Melanoma 27107696 "Exogenous expression of miR-542-3p resulted in marked inhibition of melanoma cell migration, invasion and epithelial-mesenchymal transition (EMT) in vitro and lung metastasis in vivo." genetics_overexpression_suppress hsa-mir-34a Lung Neoplasms 27109632 Systemic and local injection of ghR-form miR-34a (ghR-34a) suppressed tumor growth in a mouse model of RAS-induced lung cancer. genetics_overexpression_suppress hsa-mir-130b Lupus Nephritis 27111096 overexpressing miR-130b suppressed signaling downstream from the type I IFN pathway in RMCs by targeting IFN regulatory factor 1 (IRF-1). genetics_overexpression_suppress hsa-mir-1180 Bladder Neoplasms 27112784 miR-1180-5p also suppressed the tumor growth in vivo significantly genetics_overexpression_suppress hsa-mir-9 Schizophrenia 27117414 "Overexpression of miR-9 was sufficient to ameliorate a previously reported neural migration deficit in SZ NPCs, whereas knockdown partially phenocopied aberrant migration in control NPCs." genetics_overexpression_suppress hsa-mir-182 Osteosarcoma 27123060 "upregulation of miRNA-182 promotes cell apoptosis and inhibits cell viability, proliferation, invasion and migration." genetics_overexpression_suppress hsa-let-7i "Carcinoma, Hepatocellular" 27126374 "Let-7i was downregulated in HCC tissues, and transfection of HuH-7 with let-7i inhibited malignant cell behaviors and decreased IGF2BPs transcripts." genetics_overexpression_suppress hsa-mir-214 "Carcinoma, Hepatocellular" 27129291 Overexpression of miR-214 significantly attenuated cell proliferation. genetics_overexpression_suppress hsa-mir-429 Cervical Neoplasms 27133071 "miR-429 over-expression and inhibition on cell elongation, migration, stress fiber formation, and invasion." genetics_overexpression_suppress hsa-mir-370 Glioma 27138069 Overexpression of miR-370-3p showed a significant inhibitory effect on cell proliferation and accompanied cell cycle G0/G1 arrest in U251 and U87-MG cells. genetics_overexpression_suppress hsa-mir-199b Colorectal Carcinoma 27145368 restoration of miR-199b considerably reduced cell invasion and migration in vitro and in vivo genetics_overexpression_suppress hsa-mir-223 Inflammation 27148749 The overexpression of miR-223 in both J774A.1 and peritoneal macrophages induced a phenotypic change from M1 to M2 state genetics_overexpression_suppress hsa-mir-133a Glioma 27154818 "Transfection of miR-150-5p or miR-133a mimics into glioma cell lines reduced MT1-MMP expression and MMP-2 activation by these cells, and cell proliferation and invasion/migration were also suppressed by it." genetics_overexpression_suppress hsa-mir-150 Glioma 27154818 "Transfection of miR-150-5p or miR-133a mimics into glioma cell lines reduced MT1-MMP expression and MMP-2 activation by these cells, and cell proliferation and invasion/migration were also suppressed by it." genetics_overexpression_suppress hsa-mir-140 Biliary Tract Neoplasms 27155525 Ectopic expression of miR-140-5p markedly decreased SEPT2 protein concentration in BTC cells and suppressed cell proliferation and colony formation in vitro. genetics_overexpression_suppress hsa-mir-130a "Leukemia, Myeloid, Chronic" 27158382 over-expression of miR-130a in A562 CML cells dramatically suppresses cell proliferation and induces cell apoptosis both in vitro and in vivo. genetics_overexpression_suppress hsa-mir-26a Ovarian Neoplasms 27158389 over-expression could significantly inhibit the proliferation of ovarian cancer cells and induce their apoptosis. genetics_overexpression_suppress hsa-mir-1 "Squamous Cell Carcinoma, Head and Neck" 27169691 miR-1 and miR-206 significantly inhibited HNSCC cells' aggressiveness. genetics_overexpression_suppress hsa-mir-206 "Squamous Cell Carcinoma, Head and Neck" 27169691 restoration of miR-1 and miR-206 significantly inhibited HNSCC cells' aggressiveness. genetics_overexpression_suppress hsa-mir-196a "Carcinoma, Renal Cell" 27175581 "miRâ€?96a suppressed cell proliferation, apoptosis and migration of the 786‑O and ACHN RCC cell lines." genetics_overexpression_suppress hsa-mir-195 Prostate Neoplasms 27175617 "miR-195 overexpression inhibited cell proliferation, cell cycle progression and tumorigenesis via directly targeting HMGA1." genetics_overexpression_suppress hsa-mir-126 Thyroid Neoplasms 27175968 "upregulation of miRâ€?26 inhibited cell proliferation, migration and invasion in thyroid cancer cells." genetics_overexpression_suppress hsa-mir-34a Glioma 27176117 "Overexpression of miRâ€?4a inhibited proliferation, and induced apoptosis of U87 cells." genetics_overexpression_suppress hsa-mir-497 Osteosarcoma 27176490 "upregulation of miRâ€?97 inhibited cell proliferation, migration and invasion in osteosarcoma cell lines" genetics_overexpression_suppress hsa-mir-223 "Carcinoma, Lung, Non-Small-Cell" 27177336 "The overexpression of miRâ€?23 may partially reverse the acquired resistance to epidermal growth factor receptor-TKIs, thus, providing a potential therapeutic strategy for TKI-resistant NSCLC." genetics_overexpression_suppress hsa-mir-191 "Carcinoma, Lung, Non-Small-Cell" 27178817 cell proliferation was notably reduced by the miR-1908 mimic transfection genetics_overexpression_suppress hsa-mir-126 Atherosclerosis 27180261 miR-126 up-regulation activates EPCs and ECs and contributes to vascular healing and neovessel formation genetics_overexpression_suppress hsa-mir-328 Cervical Neoplasms 27181358 Enforced expression of miR-328 led to a decline in the expression of endogenous TCF7L2 in cervical cancer cells. genetics_overexpression_suppress hsa-mir-448 "Squamous Cell Carcinoma, Oral" 27184799 Knockdown of N4BP2L1 and upregulation of miR-448 significantly reduced the invasive potential of oral squamous cell carcinoma cells. genetics_overexpression_suppress hsa-mir-544 "Carcinoma, Breast, Triple Negative" 27186677 "overexpression of miR-544 in triple negative breast cancer cells significantly down-regulated expressions of Bcl6 and Stat3, which in turn severely inhibited cancer cell proliferation, migration and invasion in vitro." genetics_overexpression_suppress hsa-mir-145 Ovarian Neoplasms 27191261 Activating miR-145 suppresses ovarian tumor growth and metastasis genetics_overexpression_suppress hsa-let-7c Kidney Injury 27203438 miR-let7c-MSC therapy attenuated kidney injury genetics_overexpression_suppress hsa-mir-30a Gastric Neoplasms 27208176 forced miR-30a over-expression in cancer cells can be a potential way to inhibit tumour development. genetics_overexpression_suppress hsa-mir-320a Prostate Neoplasms 27212625 Restoration of mature miRâ€?20a in PCa cell lines showed that miRâ€?20a significantly inhibited cancer cell migration and invasion. genetics_overexpression_suppress hsa-mir-320 Prostate Neoplasms 27216188 An miR-320a mimic suppressed AR protein expression together with growth suppression genetics_overexpression_suppress hsa-mir-192 "Adenocarcinoma, Pancreatic Ductal" 27216198 overexpression of miR-192 was sufficient to reduce cell proliferation and invasion. genetics_overexpression_suppress hsa-mir-150 Atherosclerosis 27216461 The suppressive effects of miR-150 on macrophage foam cell formation are mediated through targeting of AdipoR2. genetics_overexpression_suppress hsa-mir-19a Hypoxia 27220268 miR-19a overexpression clearly ameliorated hypoxia-induced cell death (necrosis and apoptosis) genetics_overexpression_suppress hsa-mir-34a "Carcinoma, Laryngeal" 27220728 expression of miR-34a inhibited cell proliferation and migration in laryngeal carcinoma cells. genetics_overexpression_suppress hsa-mir-495 Glioma 27220777 restoration of hsa-miR-495 inhibited glioma cell proliferation and invasion in vitro. genetics_overexpression_suppress hsa-mir-18b Melanoma 27220837 Ectopic expression of miR-18b decreased the proliferation of A375 and B16 cells genetics_overexpression_suppress hsa-mir-874 Colorectal Carcinoma 27221209 expression of miR-874 was downregulated in CRC tissues and cell lines genetics_overexpression_suppress hsa-mir-410 Breast Neoplasms 27221455 "miR-410-3p overexpression reduced cell growth, colony formation and the number of EdU-positive cells in the MDA-MB-231 cells." genetics_overexpression_suppress hsa-mir-181a Cardiomegaly 27221738 "Over-expression of miR-30c or miR-181a decreased expression of p53, p21, ANP, cardiomyocyte cell size, and apoptosis in HG-treated cardiomyocytes." genetics_overexpression_suppress hsa-mir-375 Colorectal Carcinoma 27222350 "miR-375 inhibited proliferation, invasion and migration in DLD1 and HCT8 cells." genetics_overexpression_suppress hsa-mir-224 Osteosarcoma 27222381 "overexpression of miR-224 suppressed osteosarcoma cell proliferation, migration and invasion" genetics_overexpression_suppress hsa-mir-214 Kidney Neoplasms 27226530 miR-214 significantly blocked IGF-1R-forced renal cancer cell proliferation genetics_overexpression_suppress hsa-mir-137 Melanoma 27233613 Overexpression of miR-137 decreased cell proliferation and colony formation in vitro. genetics_overexpression_suppress hsa-mir-126 "Carcinoma, Lung, Non-Small-Cell" 27236384 "Upregulation of miR-126 resulted in the decrease of the proliferation, migration, and invasive abilities of A549 cells" genetics_overexpression_suppress hsa-mir-208b Myocardial Infarction 27236543 Overexpressing miR-208b improved myocardial functions genetics_overexpression_suppress hsa-mir-134 "Carcinoma, Lung, Non-Small-Cell" 27241841 miR-134 suppressed tumour growth of A549 xenograft in nude mice. genetics_overexpression_suppress hsa-mir-17 Mesothelioma 27245839 Transfection of MPM cells with a miR-17-5p mimic or KCNMA1-specific siRNAs reduced mRNA expression of KCa1.1 and inhibited MPM cell migration. genetics_overexpression_suppress hsa-mir-450 Lung Neoplasms 27246609 transfection with lentivirus carrying miRâ€?50 upregulated miRâ€?50 expression and significantly attenuated lung cancer cell proliferation and invasion genetics_overexpression_suppress hsa-mir-1 "Squamous Cell Carcinoma, Esophageal" 27247259 miRâ€? suppressed ESCC cell proliferation and increased apoptosis genetics_overexpression_suppress hsa-mir-124 "Carcinoma, Lung" 27251409 overexpression of miR-124 in A549 cells suppressed cell migration and invasion activity genetics_overexpression_suppress hsa-mir-218 "Cardiomyopathy, Hypertrophic" 27258257 Overexpression of miR-218 is sufficient to reduce hypertrophy genetics_overexpression_suppress hsa-mir-497 Ischemia-Reperfusion Injury 27261611 miR-497 could inhibit inflammation and apoptosis of spinal cord IR through its targets genetics_overexpression_suppress hsa-mir-744 Cervical Neoplasms 27261616 "up-regulation of miR-744 and down-regulation of Bcl-2 could stimulate Caspase-3 expression, promoting apoptosis of cervical cancer cells." genetics_overexpression_suppress hsa-mir-663a "Carcinoma, Hepatocellular" 27261623 "miR-663a distinctly inhibited cell proliferation, migration and invasion." genetics_overexpression_suppress hsa-mir-411 Breast Neoplasms 27264952 Ectopic expression of miR-411-5p suppressed the breast cancer cell proliferation genetics_overexpression_suppress hsa-mir-26a Osteosarcoma 27270422 miR-26a overexpression inhibits the tumor cell growth both in vitro and in vivo. genetics_overexpression_suppress hsa-mir-106b Atherosclerosis 27270534 Overexpression of miR-106b-5p with miR-106b-5p mimic inhibited PTEN expression and TNF-α-induced apoptosis in HUVEC. genetics_overexpression_suppress hsa-mir-29b Liver Cirrhosis 27273381 miR-29b overexpression inhibited proliferation of LX-2 cells 24 h after transfection. genetics_overexpression_suppress hsa-mir-320 "Carcinoma, Lung, Non-Small-Cell" 27277534 "miRâ€?20 inhibited cell growth, migration and invasion in NSCLC cells." genetics_overexpression_suppress hsa-mir-375 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 27279635 "Overexpression of miR-375 led to a decreased protein level of Krüppel-like factor 4 (KLF4) and marked suppression of the proliferation and invasion, and induced apoptosis of LSCC cell line" genetics_overexpression_suppress hsa-mir-24 "Carcinoma, Endometrial" 27279639 Up-regulation of miR-24 inhibited the cell proliferation genetics_overexpression_suppress hsa-mir-205 Colon Neoplasms 27283988 miR-205 decreases cell proliferation and decreases migratory and invasive potential of colon cancer cells genetics_overexpression_suppress hsa-mir-486 Colorectal Carcinoma 27284245 overexpression of miR-486-5p inhibited the tumor growth and lymphangiogenesis in nude mice genetics_overexpression_suppress hsa-mir-210 Intervertebral Disc Degeneration 27284319 downregulation of miR-210 may promote Fas-mediated apoptosis in human IDD by regulating the expression of HOXA9. genetics_overexpression_suppress hsa-mir-214 Ischemia-Reperfusion Injury 27288437 Overexpression of the two miRs in cardiomyocytes mimics the effects of carvedilol genetics_overexpression_suppress hsa-mir-145 Liver Fibrosis 27289031 over-expression of miR-145 inhibited TGF-β1-induced the activation and proliferation of HSC-T6 cells in vitro. genetics_overexpression_suppress hsa-mir-210 Colorectal Carcinoma 27293381 miR-210 mediated the induction of apoptosis genetics_overexpression_suppress hsa-mir-153 Glioma 27295037 "Exogenous overexpression of miR-153 downregulated Rictor (mRNA and protein) and decreased p-Akt Ser473 in U87MG cells, leading to significant growth inhibition and apoptosis activation." genetics_overexpression_suppress hsa-let-7 Neoplasms [unspecific] 27295554 genetic rescue of Let-7 miRNA activity in Dicer1-deficient TAMs partly restored their M2-like phenotype and decreased tumour-infiltrating CTLs. genetics_overexpression_suppress hsa-mir-10b Cervical Neoplasms 27296950 overexpression of miR-10b in cervical cancer cells could inhibit the cell proliferation and invasion genetics_overexpression_suppress hsa-mir-34b "Leukemia, Myeloid, Acute" 27296951 the miR-34b mimicked transfection-mediated restoration of miR-34b inhibited cell viability and promoted cell apoptosis of HL-60 and OCI-AML3 cell lines. genetics_overexpression_suppress hsa-mir-149 "Carcinoma, Hepatocellular" 27300349 Overexpression of miR-149 or inhibition of PARP-2 expression could inhibit tumor growth but was more effective in sensitizing chemotherapy and radiotherapy in xenograft HCC animal models genetics_overexpression_suppress hsa-mir-196b Lung Neoplasms 27302168 miR-196b reexpression also significantly reduced the growth of tumor xenografts. genetics_overexpression_suppress hsa-mir-34 Pulmonary Hypertension 27302634 "miR-34a overexpression down-regulated platelet-derived growth factor receptor alpha (PDGFRA) expression, which is a key factor in PAH development." genetics_overexpression_suppress hsa-mir-497 Breast Neoplasms 27303812 "Enforced miR-497 expression, accompanied with SMAD7 reduction, suppressed MDA-MB-231 and MCF-7 breast cancer cell growth" genetics_overexpression_suppress hsa-mir-26b Bladder Neoplasms 27310702 Restoration of these miRNAs inhibited cell migration and invasion in BC. genetics_overexpression_suppress hsa-mir-674 Liver Injury 27313091 miR-674-5p might be a negative regulator in 5-LO mediated autoimmune liver injury genetics_overexpression_suppress hsa-mir-20a "Carcinoma, Hepatocellular" 27313460 growth of HepG2 cells in the miR-20a mimics group was significantly inhibited genetics_overexpression_suppress hsa-mir-27a "Carcinoma, Renal Cell" 27313769 upregulated miR-27a attenuated RCC tumor growth in the tumor xenograft animal model genetics_overexpression_suppress hsa-mir-494 Ovarian Neoplasms 27313773 Overexpression of miR-494 inhibited ovarian cancer cell proliferation by inducing apoptosis. genetics_overexpression_suppress hsa-mir-218 "Carcinoma, Renal Cell" 27314976 cell proliferation was suppressed in miRâ€?18 mimic‑transfected RCC cells compared with control cells genetics_overexpression_suppress hsa-mir-23a Osteoarthritis 27318087 miR-23a-3p overexpression suppresses type II collagen and aggrecan expression genetics_overexpression_suppress hsa-mir-206 "Carcinoma, Breast, Triple Negative" 27318091 The miR-206 mimics inhibited TNBC breast cell invasion and angiogenesis. genetics_overexpression_suppress hsa-let-7 Endometriosis 27320036 increased let-7f expression effectively reduced the migration of endometrial cells. genetics_overexpression_suppress hsa-let-7f Endometriosis 27320036 increased let-7f expression effectively reduced the migration of endometrial cells. genetics_overexpression_suppress hsa-mir-137 Glioblastoma 27328425 "overexpression of miR-137 in GBM cells also inhibited cell proliferation, migration, and invasion." genetics_overexpression_suppress hsa-mir-148b Breast Neoplasms 27328731 "Depleting miR-214 or elevating miR-148b blocked the dissemination of melanoma or breast cancer cells, an effect that could be accentuated by dual alteration." genetics_overexpression_suppress hsa-mir-148b Melanoma 27328731 "Depleting miR-214 or elevating miR-148b blocked the dissemination of melanoma or breast cancer cells, an effect that could be accentuated by dual alteration." genetics_overexpression_suppress hsa-mir-30b "Carcinoma, Hepatocellular" 27333771 Gain- and loss-of-function studies revealed that miR-30b could dramatically inhibit in vitro HCC cell migration and invasion. genetics_overexpression_suppress hsa-mir-141 "Carcinoma, Renal Cell, Clear-Cell" 27336447 a tumor suppressive effect of miR-141-3p and miR-145-5p by decreasing migration and invasion of RCC cells could be shown. genetics_overexpression_suppress hsa-mir-145 "Carcinoma, Renal Cell, Clear-Cell" 27336447 a tumor suppressive effect of miR-141-3p and miR-145-5p by decreasing migration and invasion of RCC cells could be shown. genetics_overexpression_suppress hsa-mir-18a "Carcinoma, Breast, Triple Negative" 27338042 Enforced miR-18a overexpression directly led to increased autophagy in MDA-MB-231 cells genetics_overexpression_suppress hsa-mir-126 Age-Related Macular Degeneration 27338342 overexpression effects of miR-126 were also proven on human microvascular endothelial cells genetics_overexpression_suppress hsa-mir-156a "Carcinoma, Nasopharyngeal" 27341697 synthetic miR156a mimic inhibited the EMT of NPC cells in vitro. genetics_overexpression_suppress hsa-mir-376c Cervical Neoplasms 27345009 "Upregulation of miR-376c impaired cell proliferation, blocked G1/S checkpoint of cell cycle and suppressed cell invasion in vitro." genetics_overexpression_suppress hsa-mir-195 Colon Neoplasms 27347317 "Overexpression of miR-195-5p inhibited cellular growth, suppressed cellular migration and invasion, and led to cell cycle arrest at G1 phase in vitro." genetics_overexpression_suppress hsa-mir-132 Chronic Pain 27349406 Spinal administration of miR-132-3p antagonists via intrathecal (i.t.) catheters dose dependently reversed mechanical allodyina (p<0.001) and eliminated pain behavior genetics_overexpression_suppress hsa-mir-24 Cerebral Ischemia 27349868 miR-24 overexpression or silencing of neurocan shows an antihypoxic effect in SH-SY5Y cells. genetics_overexpression_suppress hsa-mir-24 Lacrimal Adenoid Cystic Carcinoma 27351203 overexpression of miR-24-3p decreased its malignant phenotype. genetics_overexpression_suppress hsa-mir-449a Lung Fibrosis 27351886 miR-449a significantly reduced both the distribution and severity of lung lesions induced by silica. genetics_overexpression_suppress hsa-mir-410 Systemic Lupus Erythematosus 27351906 overexpression of miR-410 significantly reduced the expression levels of IL-10. genetics_overexpression_suppress hsa-mir-548an Pancreatic Neoplasms 27353169 overexpression of miR-548an significantly inhibited the proliferation and invasion of pancreatic cancer cell genetics_overexpression_suppress hsa-mir-140 Gastric Neoplasms 27353653 miR-140 overexpression inhibited HGC-27 cell viability and colony formation and resulted in G0/G1 arrest. genetics_overexpression_suppress hsa-mir-139 Bladder Neoplasms 27355528 Gain-of-function studies showed that miR-139-5p and miR-139-3p significantly inhibited cell migration and invasion by BC cells. genetics_overexpression_suppress hsa-mir-335 Bladder Neoplasms 27356628 Overexpression of miRâ€?35 in T24 cells inhibited cell proliferation and induced apoptosis genetics_overexpression_suppress hsa-mir-200b "Carcinoma, Lung, Non-Small-Cell" 27356635 Overexpression of miRâ€?00b significantly inhibited NSCLC cell migration and invasion. genetics_overexpression_suppress hsa-mir-143 "Squamous Cell Carcinoma, Esophageal" 27358073 Ectopic expression of miR-143-3p also reduced the metastatic potential of cells by selectively regulating epithelial-mesenchymal transition regulatory proteins. genetics_overexpression_suppress hsa-mir-330 Cutaneous Melanoma 27363653 Enforced expression of miR-330-5p inhibits malignant CMM cells proliferation and migration and led to downregulation of the TYR and PDIA3 protein. genetics_overexpression_suppress hsa-mir-145 "Carcinoma, Breast, Triple Negative" 27364572 Upregulating miR-145 in HCC1937 cells dramatically suppressed cell proliferation and induced G1-phase arrest genetics_overexpression_suppress hsa-mir-124 "Carcinoma, Lung, Non-Small-Cell" 27376157 "Overexpression of miR-124 significantly suppresses tumor cell proliferation, colony formation, migration, and induction of apoptosis in H322 and A549 cells." genetics_overexpression_suppress hsa-mir-26a "Fatty Liver, Non-Alcoholic" 27377869 LV-26a-infected mice were protected from glucose dysmetabolism and showed markedly decreased total liver weight genetics_overexpression_suppress hsa-mir-125b Ovarian Neoplasms 27383536 Ectopic expression of miR-125b in EOC cells significantly inhibited tumor invasion. genetics_overexpression_suppress hsa-mir-106a Osteosarcoma 27383537 "Downregulation of miR-106a-5p was found in OS tissues, and upregulation of miR-106a-5p can inhibit the proliferation, migration, and invasion by targeting HMGA2 in OS cells." genetics_overexpression_suppress hsa-mir-210 Acute Ischemic Stroke 27390218 Lentivirus-mediated miR-210 overexpression enhanced the microvessel density and the number of neural progenitor cells in the ischemic mouse brain (P < 0.05) and improved neurobehavioral outcomes in the ischemic mouse (P < 0.05). genetics_overexpression_suppress hsa-mir-7 "Carcinoma, Hepatocellular" 27391479 Overexpression of miR-7 inhibited the HCC cell proliferation and invasion. Overexpression of miR-7 could suppress the direct target gene CCNE1 and PIK3CD expression. genetics_overexpression_suppress hsa-mir-185 Idiopathic Pulmonary Fibrosis 27392970 "Furthermore, mimics of miR-185 and miR-186 blocked transforming growth factor-β-induced collagen V overexpression and alleviated transforming growth factor-β-induced epithelial-mesenchymal transition in A549 cells and HCC827 cells." genetics_overexpression_suppress hsa-mir-186 Idiopathic Pulmonary Fibrosis 27392970 "Our findings suggest that attenuated expression of miR-185 and miR-186 may be responsible for collagen V overexpression during idiopathic pulmonary fibrosis, and these miRNAs may serve as pathogenesis-related biomarkers and treatment targets." genetics_overexpression_suppress hsa-mir-449a "Carcinoma, Hepatocellular" 27398144 "Ectopic expression of miR-449a suppressed HCC cell proliferation, colony formation, migration and invasion." genetics_overexpression_suppress hsa-mir-146a Liver Cirrhosis 27399683 "Overexpression of miR-146a-5p inhibited LPS induced pro-inflammatory cytokines secretion through down-regulating the expression levels of TLR-4, IL-1 receptor-associated kinase 1 (IRAK1), TNF receptor associated factor-6 (TRAF6) and phosphorylation of nuclear factor-kappa B (NF-κB)." genetics_overexpression_suppress hsa-mir-200 "Carcinoma, Breast, Triple Negative" 27402080 "miR-9 and miR-200 promoted and inhibited, respectively, the formation of vascular-like structures in vitro" genetics_overexpression_suppress hsa-mir-149 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 27403438 In vitro studies revealed that the exogenous expression of miRNA-149 inhibits the proliferation of human Hep-2 cells and induces cell apoptosis. genetics_overexpression_suppress hsa-mir-218 Chronic Obstructive Pulmonary Disease 27409149 Perturbation experiments with a miR-218-5p mimic or inhibitor demonstrated a protective role of miR-218-5p in cigarette smoke-induced inflammation and COPD. genetics_overexpression_suppress hsa-mir-133a Heart Diseases [unspecific] 27411382 "Our results revealed that miR-133a mimic treatment improved the contractility of the diabetic rat's heart concomitant with upregulation of TH, cardiac NE, β-AR, and downregulation of TAT and plasma levels of NE." genetics_overexpression_suppress hsa-mir-141 "Carcinoma, Hepatocellular" 27412940 "Over-expression of miR-141 inhibits the proliferation, invasion and migration of hepatocellular carcinoma MHCC-97H cells" genetics_overexpression_suppress hsa-mir-149 Colorectal Carcinoma 27415661 "Re-expression of miR-149 could enhance the 5-FU sensitivity of 5-FU-resistant CRC cells by increasing 5-FU-inducing apoptosis, while downregulation of miR-149 could decrease the 5-FU sensitivity of parental CRC cells by decreasing 5-FU-inducing apoptosis" genetics_overexpression_suppress hsa-mir-18a "Carcinoma, Hepatocellular" 27421245 "We transfected HepG2.2.15 with miR-18a mimics and CTGF siRNA, finding that upregulated miR-18a and downregulated CTGF suppress the viability and cause cell cycle arrest." genetics_overexpression_suppress hsa-mir-34a Leukemia 27424989 "Induced expression of miR-34a in TIM3 positive leukemia stem cells (LSC), inhibits the clonogenic expansion, tumor progression and metastasis of leukemia." genetics_overexpression_suppress hsa-mir-320b "Carcinoma, Nasopharyngeal" 27428374 "Further studies showed that overexpression of miR-320b suppressed NPC cell proliferation and enhanced mitochondrial fragmentation and apoptosis both in vitro and in vivo, while silencing of miR-320b promoted tumor growth and suppressed apoptosis." genetics_overexpression_suppress hsa-mir-497 Invasive Bladder Transitional Cell Carcinoma 27430325 "We also found that overexpression of miR-497 inhibited the proliferation, migration and invasion of bladder cancer cells by downregulating E2F3 (an miR-497 target gene) mRNA and protein and that siRNA against E2F3 inhibited cell proliferation, migration and invasion, which was similar to the effect of miR-497 overexpression in the BTCC cells." genetics_overexpression_suppress hsa-mir-338 Lung Neoplasms 27431198 "Regaining the expression of miR-338 in lung cancer cell lines significantly impaired cellular adhesion, migration, invasion and lung tumor formation in nude mice." genetics_overexpression_suppress hsa-mir-184 "Carcinoma, Renal Cell" 27431728 "Overexpression of pre-miR-184 changed the metabolic and proliferation features of ccRCC cells by reducing cell glucose consumption, lactate production and cell proliferation." genetics_overexpression_suppress hsa-mir-183 "Carcinoma, Nasopharyngeal" 27431799 "Using transient or stable transfection, we showed that ectopic expression of miR-96 and miR-183 suppressed cell growth and tumor sphere formation in NPC." genetics_overexpression_suppress hsa-mir-96 "Carcinoma, Nasopharyngeal" 27431799 "Using transient or stable transfection, we showed that ectopic expression of miR-96 and miR-183 suppressed cell growth and tumor sphere formation in NPC." genetics_overexpression_suppress hsa-mir-30a Prostate Neoplasms 27431942 "miRâ€?0a overexpression resulted in a significant suppression of cell growth in vitro, and reduced tumorigenicity in vivo." genetics_overexpression_suppress hsa-mir-200c Lung Neoplasms 27432063 "Over expression of miR-200c could significantly inhibit cell proliferation, induce G0/G1 cell cycle arrest and induce cell apoptosis." genetics_overexpression_suppress hsa-mir-27a "Squamous Cell Carcinoma, Oral" 27432214 "Intriguingly, increased expression of miR-27a-3p could significantly decrease the expression level of YAP1 as well as several epithelial to mesenchymal transition (EMT)-related molecules in OSCC cell lines, including Twist and Snail." genetics_overexpression_suppress hsa-mir-199a Testicular Neoplasms 27432288 it was determined that overexpression of miRâ€?99aâ€?p in Nteraâ€? cells caused suppression of cell growth and migration. genetics_overexpression_suppress hsa-mir-541 "Carcinoma, Lung, Non-Small-Cell" 27448300 We found that expression of miR-541-3p was decreased obviously in NSCLC tissues and plasma. Down-regulation of miR-541-3p was associated with TNM stage and postoperative survival. genetics_overexpression_suppress hsa-mir-26a Prostate Neoplasms 27449037 It was confirmed that miR-26a-5p was markedly downregulated in PC tissues compared with normal controls whose reduced expression was significantly associated with metastasis and poor overall prognosis and found that miR-26a-5p was able to prevent proliferation and motility of PC cells in vitro. genetics_overexpression_suppress hsa-mir-613 Breast Neoplasms 27449609 "miR-613 mimics significantly inhibited the migration and invasion of breast cancer cells, whereas miR-613 inhibitors significantly increased cell migration and invasion." genetics_overexpression_suppress hsa-mir-455 Gastric Neoplasms 27451075 "re-expression of miR-455-5p could inhibit human GC cell proliferation and invasion, overexpression of miR-455-5p could also promote GC cell apoptosis." genetics_overexpression_suppress hsa-mir-338 "Carcinoma, Lung, Non-Small-Cell" 27453416 Forced expression of miR-338-3p in A549 cells led to the suppression of migration/invasion capacity and inhibition of epithelial markers. genetics_overexpression_suppress hsa-mir-34a "Carcinoma, Cervical" 27456356 "While forced expression of miR-34a in CaCx and CRC cells inhibited HMGB1 mRNA and protein levels, proliferation, migration and invasion, inhibition of endogenous miR-34a enhanced these tumourigenic properties." genetics_overexpression_suppress hsa-mir-34a Colorectal Carcinoma 27456356 "While forced expression of miR-34a in CaCx and CRC cells inhibited HMGB1 mRNA and protein levels, proliferation, migration and invasion, inhibition of endogenous miR-34a enhanced these tumourigenic properties." genetics_overexpression_suppress hsa-mir-497 Breast Neoplasms 27456360 "Further, overexpression of miR-497 not only inhibited ERRα expression but also reduced MIF level and MMP9 activity, which led to significant decreases in cell proliferation, migration, and invasion of ERα negative breast cancer." genetics_overexpression_suppress hsa-mir-15a "Carcinoma, Nasopharyngeal" 27458095 "As a result, miR-15a overexpression significantly reduced cell proliferation (pâ€?â€?.01 or pâ€?â€?.001) and induced cell apoptosis (pâ€?â€?.001), while miR-15a suppression got the opposite result for cell proliferation and apoptosis." genetics_overexpression_suppress hsa-mir-451 "Carcinoma, Hepatocellular" 27461244 "In this study, overexpression of miR-451 clearly attenuated the promoting effects of HCC cells on cell proliferation, migration and tube formation of human umbilical vein endothelial cells (HUVECs)." genetics_overexpression_suppress hsa-mir-1207 "Carcinoma, Hepatocellular" 27461404 Overexpression of miR-1207-5p significantly suppressed the cell growth and invasion of HCC cells. genetics_overexpression_suppress hsa-mir-34c Prostate Neoplasms 27461446 "In this study, we identified that miR-34C was under-expressed in the purified CD133+ PCSCs and enforced introduction of miR-34C attenuated the stemness of CD133+ PCSCs." genetics_overexpression_suppress hsa-mir-520a Lymphoma 27461820 "Our data indicated that the mimics of miRâ€?20a inhibited growth, proliferation of Raji cells and promoted its apoptosis, which was related to downregulation of AKT1, NF‑κB and ER stress response mediated by PERK/eIF2α pathway." genetics_overexpression_suppress hsa-mir-520a "Lymphoma, Burkitt" 27461820 "Our data indicated that the mimics of miRâ€?20a inhibited growth, proliferation of Raji cells and promoted its apoptosis, which was related to downregulation of AKT1, NF‑κB and ER stress response mediated by PERK/eIF2α pathway." genetics_overexpression_suppress hsa-mir-520a "Lymphoma, Hodgkin" 27461820 "Our data indicated that the mimics of miRâ€?20a inhibited growth, proliferation of Raji cells and promoted its apoptosis, which was related to downregulation of AKT1, NF‑κB and ER stress response mediated by PERK/eIF2α pathway." genetics_overexpression_suppress hsa-mir-520a "Lymphoma, Non-Hodgkin" 27461820 "Our data indicated that the mimics of miRâ€?20a inhibited growth, proliferation of Raji cells and promoted its apoptosis, which was related to downregulation of AKT1, NF‑κB and ER stress response mediated by PERK/eIF2α pathway." genetics_overexpression_suppress hsa-mir-132 "Carcinoma, Hepatocellular" 27467251 The tumor-suppressive role of miR-132 in HCC has been further confirmed by in vitro experiments. genetics_overexpression_suppress hsa-mir-203 Glioblastoma 27467502 Conversely reconstitution of miR-203 expression induced apoptosis and inhibited migratory property of glioma cells. genetics_overexpression_suppress hsa-mir-26a Osteosarcoma 27468358 "Using in vitro and in vivo assays, we confirmed that miR-26a could inhibit the abilities of in vitro proliferation and suppress in vivo tumor growth in mouse model." genetics_overexpression_suppress hsa-mir-205 "Carcinoma, Breast" 27468619 Knock-up of miR-205 expression by transfection with its mimics promoted MDA-MB-468 cells apoptosis (P=0.006 1). genetics_overexpression_suppress hsa-mir-137 "Carcinoma, Gastric" 27468717 "Over expression of miR-137 could inhibit the cell migration, proliferation, and promote cell cycle arrest in G0/G1 stage in BGC-823 and SGC-7901 cell lines." genetics_overexpression_suppress hsa-mir-182 "Carcinoma, Renal Cell, Clear-Cell" 27468875 "Compared to the control group, cell viability, colony-forming ability, and numbers of migrated and invaded cells were significantly decreased by transfection with miR-182 mimic but were markedly increased by miR-182 inhibitor (all P < 0.05)." genetics_overexpression_suppress hsa-mir-148a "Carcinoma, Ovarian" 27470550 "Moreover, cell experiments confirmed that miR-148a could inhibit proliferation, migration and invasion of ovarian cancer cells." genetics_overexpression_suppress hsa-mir-122 Cholangiocarcinoma 27472451 "MiR-122 overexpression reduced cell invasion and migration ability, and inhibited cell apoptosis and p53 expression. Inhibiting miR-122 caused the opposite results." genetics_overexpression_suppress hsa-mir-451 Glioma 27476171 "By targeting CAB 39, miRNA-451 likely triggers the LKB1/AMPK/PI3K/AKT pathway, which regulates GLUT1, to inhibit the glucose metabolism of, reduce the energy supply to, and inhibit the proliferation and invasion of glioma cells." genetics_overexpression_suppress hsa-mir-29b Wound Healing 27477081 "Importantly, local delivery of miR-29b lentiviral particles inhibited HSP47 expression and collagen biosynthesis as well as suppressed angiogenesis, thus reducing scar formation in an excisional wound splinting model." genetics_overexpression_suppress hsa-mir-194 "Squamous Cell Carcinoma, Esophageal" 27480251 miR-194 was found to inhibit proliferation and invasion and promote apoptosis of esophageal squamous cell carcinoma cells. genetics_overexpression_suppress hsa-mir-203 Glioblastoma 27484906 MicroRNA-203 transfected GBM-SCs had reduced capacity for self-renewal in the cell sphere assay and increased expression of glial and neuronal differentiation markers. genetics_overexpression_suppress hsa-mir-26a Vascular Hypertrophy 27485101 "Taken together, the present study suggested an anti‑hypertrophic role of miRâ€?6a in cardiac hypertrophy, possibly via inhibition of GATA4." genetics_overexpression_suppress hsa-mir-101 "Carcinoma, Bladder" 27485165 "In addition, plasmid‑mediated overexpression of miRâ€?01 and small hairpin RNA‑mediated inhibition of c‑FOS significantly inhibited the proliferation and invasive capacity of T24 cells." genetics_overexpression_suppress hsa-mir-610 Glioma 27485527 "Furthermore, the present study revealed that miRâ€?10 inhibited cell growth, migration and invasion in glioma cells." genetics_overexpression_suppress hsa-mir-329 Osteosarcoma 27487475 "MiR-329 is able to inhibit osteosarcoma cell proliferation, promote apoptosis, and induce G0/G1 cell cycle arrest." genetics_overexpression_suppress hsa-mir-29a "Carcinoma, Lung" 27488440 Restoration of miR-29a suppressed cancer cell aggressiveness and fibroblast migration. genetics_overexpression_suppress hsa-mir-29a Idiopathic Pulmonary Fibrosis 27488440 Restoration of miR-29a suppressed cancer cell aggressiveness and fibroblast migration. genetics_overexpression_suppress hsa-mir-29b Granular Corneal Dystrophy 27490049 Overexpression of miR-29b decreased ECM protein production in human corneal endothelial cells. genetics_overexpression_suppress hsa-mir-1299 "Carcinoma, Hepatocellular" 27490780 "miR-1299 overexpression inhibited cell proliferation and arrested cell cycle in G0/G1 phase analyzed by MTT assay, soft agar assay, BrdU cell proliferation assay and cell cycle assay, while miR-1299 knockdown promoted cell proliferation and accelerated G1/S transition." genetics_overexpression_suppress hsa-mir-15a Melanoma 27492455 miR-15a displayed inhibitory effects on proliferation and invasiveness of several malignant melanoma cell lines. genetics_overexpression_suppress hsa-mir-137 "Carcinoma, Hepatocellular" 27492460 "Overexpression of miR-137 via adenoviral vector inhibited the proliferation and anchorage-independent growth of HCC cells, HepG2 and MHCC-97H." genetics_overexpression_suppress hsa-mir-143 Leukemia 27492780 miRNA143 transfection inhibited K562 cell growth and induced its apoptosis. genetics_overexpression_suppress hsa-mir-3178 "Carcinoma, Gastric" 27493095 "The condition medium from miR-3178 mimic transfected GES-1 cells could inhibit proliferation and induce apoptosis of inflammation-related gastric cancer cells SGC7901 and MGC803 by decreasing the production of inflammatory cytokines TNF-α and IL-6, which were secreted by GES-1 cells." genetics_overexpression_suppress hsa-mir-187 "Carcinoma, Lung, Non-Small-Cell" 27495872 Overexpression of miR-187-5p inhibited the growth and metastasis of NSCLC cells. genetics_overexpression_suppress hsa-mir-155 Allergy 27497617 miR-155 overexpression significantly suppressed IL-13-induced secretion of CCL11 and CCL26. genetics_overexpression_suppress hsa-mir-509 "Carcinoma, Lung" 27498003 "In addition, over-expression of miR-509-3-5p markedly blocked A549 cell proliferation and sensitized the cells to CIS and ADR treatment." genetics_overexpression_suppress hsa-let-7a "Carcinoma, Colon" 27498032 Further studies demonstrated that over-expressed let-7a could remarkably inhibit HCT-116 and SW620 cell growth and metastasis by directly down-regulating Rhotekin (RTKN). genetics_overexpression_suppress hsa-mir-140 Glioma 27498787 "Restoration of miR-140 obviously suppressed glioma cell proliferation, migration and invasion." genetics_overexpression_suppress hsa-mir-205 "Carcinoma, Renal Cell" 27498834 "It was revealed that miRâ€?05 promoted the apoptosis of RCC cells and suppressed their proliferation, metastasis and invasion compared with the negative control." genetics_overexpression_suppress hsa-mir-124 Retinoblastoma 27498908 "The ectopic expression of miR-124 in the RB cell lines (Y79 and SO-RB50) suppresses cell proliferation, migration and invasion, induced cell apoptosis in vitro." genetics_overexpression_suppress hsa-mir-186 "Carcinoma, Lung, Non-Small-Cell" 27498924 "Furthermore, overexpression of miR-186 suppressed lung cancer cell proliferation, migration and invasion, and induced cell apoptosis." genetics_overexpression_suppress hsa-mir-107 "Carcinoma, Lung" 27498977 "Function assays showed that overexpression of miR-107 suppressed cell proliferation, migration and invasion in A549 cells in vitro, and inhibited NSCLC tumor growth in vivo." genetics_overexpression_suppress hsa-mir-17 "Carcinoma, Ovarian" 27499367 "Forced expression of miR-17 led to markedly diminished adhesion and invasion of ovarian cancer cells in vitro, and notably reduced metastatic nodules inside the peritoneal cavity in in vivo SKOV3 xenografts model." genetics_overexpression_suppress hsa-mir-370 "Carcinoma, Gastric" 27499479 Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer. genetics_overexpression_suppress hsa-mir-622 "Squamous Cell Carcinoma, Esophageal" 27501502 "Up-regulation of miR-622 could significantly reduce ESCC cell proliferation, enhance cell apoptosis, and impair cell invasion and migration in vitro, while down-regulation of miR-622 showed opposite effects." genetics_overexpression_suppress hsa-mir-223 Ischemia-Reperfusion Injury 27502281 Precursor miR-223 (pre-miR-223) transgenic mouse hearts exhibited better recovery of contractile performance over reperfusion period and lesser degree of myocardial necrosis than wild type hearts upon ex vivo and in vivo myocardial ischemia. genetics_overexpression_suppress hsa-mir-148b "Carcinoma, Cervical" 27505047 "miR-148b mimics significantly decreased the cell proliferation ability and invasion ability, and statistically induced apoptosis." genetics_overexpression_suppress hsa-mir-139 "Carcinoma, Cervical" 27505862 "Overexpression of miR-139-3p significantly suppressed HeLa cell proliferation, migration and invasion and induced cell apoptosis." genetics_overexpression_suppress hsa-mir-490 "Carcinoma, Breast, Triple Negative" 27506313 Gain-of-function studies revealed that miR-490-3p-3p overexpression inhibited cell growth and invasion in both MDA-MB-231 and MDA-MB-436 TNBC cells and impaired tumorigenesis of MDA-MB-231 cells in nude mice. genetics_overexpression_suppress hsa-mir-122 Bladder Neoplasms 27508026 "Furthermore, miR-122 over-expression decreases bladder cancer cell migration, invasion, colony formation in vitro and slow bladder cancer growth and angiogenesis in vivo." genetics_overexpression_suppress hsa-mir-145 Breast Neoplasms 27508031 Wound healing assay and transwell migration assay showed that ectopic expression of miR-145 significantly inhibited breast cancer cell migration. genetics_overexpression_suppress hsa-mir-338 Ovarian Neoplasms 27508048 "Restoration of miR-338-3p expression in ovarian cancer cells could inhibit cell proliferation, lactate production and lactate production of ovarian cancer cells." genetics_overexpression_suppress hsa-mir-20a "Squamous Cell Carcinoma, Esophageal" 27508097 "Together, our findings demonstrate that miR-17/20a suppresses cell migration and invasion of ESCC by modulating TGF-β/ITGB6 pathway." genetics_overexpression_suppress hsa-mir-497 "Carcinoma, Ovarian" 27513319 Overexpression of microRNA-497 suppresses cell proliferation and induces apoptosis through targeting paired box 2 in human ovarian cancer. genetics_overexpression_suppress hsa-mir-221 Lung Fibrosis 27513632 miRâ€?21 targets HMGA2 to inhibit bleomycin‑induced pulmonary fibrosis by regulating TGF‑Î?/Smad3-induced EMT. genetics_overexpression_suppress hsa-mir-106a "Carcinoma, Bladder" 27513725 Overexpression of mir-106a suppressed the proliferation of bladder cancer cell in EJ. genetics_overexpression_suppress hsa-mir-34a "Carcinoma, Gastric" 27513895 Upregulation of miR-34a enhanced the DDP sensitivity of SGC7901/DDP cells to DDP through the inhibition of cell proliferation and induction of cell apoptosis. genetics_overexpression_suppress hsa-mir-101 "Leukemia, Myeloid, Chronic" 27517565 These findings suggest that miR-101 acts as a tumor suppressor by downregulating Jak2 expression and sensitizing K562 cells to imatinib. genetics_overexpression_suppress hsa-mir-181a Leukemia 27517749 "NP-mediated upregulation of miR-181a led to reduced proliferation, impaired colony formation and increased sensitivity to chemotherapy." genetics_overexpression_suppress hsa-mir-26a "Carcinoma, Breast" 27517917 MiR-26a overexpression resulted in a reduction in cell viability that was partially recovered by inhibiting it. genetics_overexpression_suppress hsa-mir-148a "Carcinoma, Gastric" 27518872 "Ectopic expression of miR-148a inhibited tumor cell proliferation and migration in vitro, and inhibited tumor formation in vivo." genetics_overexpression_suppress hsa-let-7b Glioma 27520092 "upregulation of Let-7b, a member of the Let-7 microRNA family, inhibited proliferation, migration, and invasion in glioma cell lines." genetics_overexpression_suppress hsa-mir-34a "Carcinoma, Breast" 27524218 MiR-34a expression was remarkably down-regulated in BC tissues and cell lines compared with normal tissues and cell lines. genetics_overexpression_suppress hsa-mir-132 "Carcinoma, Prostate" 27527117 "Notably, overexpression of miR-132/212 could inhibit TGF-¦Â (transforming growth factor-¦Â)-induced EMT in Vcap and Lncap cells at both the mRNA and protein expression levels." genetics_overexpression_suppress hsa-mir-132 Prostate Neoplasms 27527117 "Notably, overexpression of miR-132/212 could inhibit TGF-¦Â (transforming growth factor-¦Â)-induced EMT in Vcap and Lncap cells at both the mRNA and protein expression levels." genetics_overexpression_suppress hsa-mir-212 "Carcinoma, Prostate" 27527117 "Notably, overexpression of miR-132/212 could inhibit TGF-¦Â (transforming growth factor-¦Â)-induced EMT in Vcap and Lncap cells at both the mRNA and protein expression levels." genetics_overexpression_suppress hsa-mir-210 Ischemic Diseases [unspecific] 27530798 "Neonatal rats show down-regulated expression of miRNA-210 after HI, suggesting that miRNA-210 may be involved in the development and progression of hypoxic-ischemic brain edema in neonatal rats." genetics_overexpression_suppress hsa-mir-15a Diabetes Mellitus 27531575 "miR-15a overexpression led to modulation toward nondiabetic levels, rather than complete inhibition of ASM and VEGF-A providing therapeutic effect without detrimental consequences of ASM and VEGF-A deficiencies" genetics_overexpression_suppress hsa-mir-15a Diabetic Retinopathy 27531575 "Over-expression of miR-15a downregulated, and inhibition of miR-15a upregulated ASM and VEGF-A expression in retinal cells." genetics_overexpression_suppress hsa-mir-1 Heart Diseases [unspecific] 27531746 We also found that microRNAs (miRNAs) 1 and 21 bind PLN strongly and relieve PLN inhibition of SERCA to a greater extent than a similar length random sequence RNA mixture. genetics_overexpression_suppress hsa-mir-21 Heart Diseases [unspecific] 27531746 We also found that microRNAs (miRNAs) 1 and 21 bind PLN strongly and relieve PLN inhibition of SERCA to a greater extent than a similar length random sequence RNA mixture. genetics_overexpression_suppress hsa-mir-613 Ischemia-Reperfusion Injury 27534371 miR-613 inhibits I/R-induced cardiomyocyte apoptosis by targeting PDCD10 by regulating the PI3K/AKT signaling pathway genetics_overexpression_suppress hsa-mir-613 Myocardial Ischemic-Reperfusion Injury 27534371 miR-613 inhibits I/R-induced cardiomyocyte apoptosis by targeting PDCD10 by regulating the PI3K/AKT signaling pathway. genetics_overexpression_suppress hsa-mir-17 Rheumatoid Arthritis 27534557 MicroRNA-17 Suppresses TNF-B Signaling by Interfering with TRAF2 and cIAP2 Association in Rheumatoid Arthritis Synovial Fibroblasts. genetics_overexpression_suppress hsa-mir-200a "Cardiomyopathy, Ischemic" 27573160 Overexpression of miR-200a protects cardiomyocytes against hypoxia-induced apoptosis by modulating the kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 signaling axis. genetics_overexpression_suppress hsa-mir-21 Ischemia-Reperfusion Injury 27593550 Overexpression of microRNA-21 protects spinal cords against transient ischemia. genetics_overexpression_suppress hsa-mir-140 Osteosarcoma 27624383 Overexpression of miR-140 Inhibits Proliferation of Osteosarcoma Cells via Suppression of Histone Deacetylase 4. genetics_overexpression_suppress hsa-mir-422a Osteosarcoma 27779704 "Overexpression of miR-422a inhibits cell proliferation and invasion, and enhances chemosensitivity in osteosarcoma cells." genetics_overexpression_suppress hsa-mir-21 "Carcinoma, Hepatocellular" 27793160 Overexpression of microRNA-21 strengthens stem cell-like characteristics in a hepatocellular carcinoma cell line. genetics_overexpression_suppress hsa-mir-126 Atherosclerosis 27827458 MicroRNA-126 overexpression rescues diabetes-induced impairment in efferocytosis of apoptotic cardiomyocytes. genetics_overexpression_suppress hsa-mir-93 Glaucoma 27878244 MicroRNA?93 is overexpressed and induces apoptosis in glaucoma trabecular meshwork cells. genetics_overexpression_suppress hsa-mir-365 "Carcinoma, Breast" 27906431 Overexpression of microRNA-365 inhibits breast cancer cell growth and chemo-resistance through GALNT4. genetics_overexpression_suppress hsa-mir-210 "Carcinoma, Pancreatic" 27940128 microRNA-210 overexpression inhibits tumor growth and potentially reverses gemcitabine resistance in pancreatic cancer. genetics_overexpression_suppress hsa-mir-34a "Carcinoma, Colon" 28035390 "overexpression of miR-34a may inhibit the proliferation, invasion and metastasis of HCT116 cells" genetics_overexpression_suppress hsa-mir-1 Heart Failure 28063219 MicroRNA-1 overexpression blunts cardiomyocyte hypertrophy elicited by thyroid hormone. genetics_overexpression_suppress hsa-mir-142 "Carcinoma, Hepatocellular" 28081734 MicroRNA-142-5p Overexpression Inhibits Cell Growth and Induces Apoptosis by Regulating FOXO in Hepatocellular Carcinoma Cells. genetics_overexpression_suppress hsa-mir-27b "Carcinoma, Lung, Non-Small-Cell" 28081743 "Overexpression of MicroRNA-27b Inhibits Proliferation, Migration, and Invasion via Suppression of MET Expression." genetics_overexpression_suppress hsa-mir-29a Glioblastoma 28212562 Overexpression of miR-29a reduces the oncogenic properties of glioblastoma stem cells by downregulating Quaking gene isoform 6. genetics_overexpression_suppress hsa-mir-519d "Adenocarcinoma, Lung" 28351305 Overexpression of miR-519d in lung adenocarcinoma inhibits cell proliferation and invasion via the association of eIF4H. genetics_overexpression_suppress hsa-mir-138 Coronary Artery Disease 28371277 Overexpression of microRNA-138 alleviates human coronary artery endothelial cell injury and inflammatory response by inhibiting the PI3K/Akt/eNOS pathway. genetics_overexpression_suppress hsa-mir-24 "Lymphoma, Hodgkin" 28432871 miR-24-3p Is Overexpressed in Hodgkin Lymphoma and Protects Hodgkin and Reed-Sternberg Cells from Apoptosis. genetics_overexpression_suppress hsa-mir-125b "Leukemia, Myeloid, Acute" 28478034 "Overexpression of microRNA-125b inhibits human acute myeloid leukemia cells invasion, proliferation and promotes cells apoptosis by targeting NF-¦ÊB signaling pathway." genetics_overexpression_suppress hsa-mir-194 Adenovirus Infection 28618953 Overexpression of microRNA-194 suppresses the epithelial-mesenchymal transition in targeting stem cell transcription factor Sox3 in endometrial carcinoma stem cells. genetics_overexpression_suppress hsa-mir-183 "Carcinoma, Nasopharyngeal" 28631568 MiR-183 overexpression inhibits tumorigenesis and enhances DDP-induced cytotoxicity by targeting MTA1 in nasopharyngeal carcinoma. genetics_overexpression_suppress hsa-mir-211 Thyroid Neoplasms 28703321 "Overexpression miR-211-5p hinders the proliferation, migration, and invasion of thyroid tumor cells by downregulating SOX11." genetics_overexpression_suppress hsa-mir-124 Cardiovascular Diseases [unspecific] 28849090 Overexpressed microRNA-506 and microRNA-124 alleviate H2O2-induced human cardiomyocyte dysfunction by targeting kr¨¹ppel-like factor 4/5. genetics_overexpression_suppress hsa-mir-506 Cardiovascular Diseases [unspecific] 28849090 Overexpressed microRNA-506 and microRNA-124 alleviate H2O2-induced human cardiomyocyte dysfunction by targeting kr¨¹ppel-like factor 4/5. genetics_overexpression_suppress hsa-mir-34a "Carcinoma, Cervical" 28893346 Overexpression of MicroRNA-34a-5p Inhibits Proliferation and Promotes Apoptosis of Human Cervical Cancer Cells by Downregulation of Bcl-2. genetics_overexpression_suppress hsa-mir-19a Colorectal Carcinoma 29207158 Overexpression of miR-19a inhibits colorectal cancer angiogenesis by suppressing KRAS expression genetics_overexpression_suppress hsa-mir-150 Ischemia-Reperfusion Injury 29328381 Overexpressing microRNA-150 attenuates hypoxia-induced human cardiomyocyte cell apoptosis by targeting glucose-regulated protein-94 genetics_overexpression_suppress hsa-mir-204 Ischemia-Reperfusion Injury 29421577 overexpression of miR-204 has a protective effect against myocardial I/R injury genetics_overexpression_suppress hsa-mir-145 Breast Neoplasms 29425746 miR-145 overexpression triggers alteration of the whole transcriptome and inhibits breast cancer development genetics_overexpression_suppress hsa-mir-143 "Carcinoma, Lung, Non-Small-Cell" 29630116 "overexpression of miR-143 downregulated cell proliferation, promoted the apoptosis, and suppressed the phosphorylation of EGFR, AKT and ERK1/2; thus, miR-143 may play a role in treatment of NSCLC to enhance therapeutic efficacy" genetics_overexpression_suppress hsa-mir-203 "Fatty Liver, Alcoholic" 29670525 over-expression of miR-203 inhibited the liver lipids accumulation and the progression of AFL by targeting Lipin1 genetics_overexpression_suppress hsa-mir-27b Atrial Fibrillation 29671258 Atrial overexpression of microRNA-27b attenuates angiotensin II-induced atrial fibrosis and fibrillation by targeting ALK5. genetics_overexpression_suppress hsa-mir-132 Heart Failure 29682535 Overexpression of microRNA-132 dramatically increased the antioxidant stress and antiapoptotic ability of H9C2 cells and decreased the expression of TGF-¦Â1 and smad3 genetics_overexpression_suppress hsa-mir-140 Intervertebral Disc Degeneration 29901170 Overexpression of miR-140-5p inhibits lipopolysaccharide-induced human intervertebral disc inflammation and degeneration by downregulating toll-like receptor 4. genetics_overexpression_suppress hsa-mir-7 "Carcinoma, Hepatocellular" 29936764 Overexpression of miR-7 can inhibit the proliferation and invasion ability of hepatocellular carcinoma cells HepG2 by downregulating Raf1 in vitro genetics_overexpression_suppress hsa-mir-410 "Carcinoma, Hepatocellular" 30086463 overexpression of miR-133a suppressed biological behaviour of HCC through TGF-¦Â/Smad3 signaling pathway other hsa-mir-142 "Leukemia, B-Cell" 12007417 A translocation that make MYC overexpression other hsa-mir-143 Colon Neoplasms 14573789 reduced miRNA levels other hsa-mir-145 Colon Neoplasms 14573789 reduced miRNA levels other hsa-mir-17 Lymphoma 16096373 "Herein, we propose a model in which the mir-17 cluster prevents excessive E2F1 activity, and thereby apoptosis, in response to activation of c-Myc." other hsa-mir-122 Hepatitis C Virus Infection 16141076 interaction with non-coding regions of Hepatitis C help its replication other hsa-mir-375 Diabetes Mellitus 16195701 mir-375 was found to modulate glucose-stimulated insulin secretion and exocytosis. other hsa-mir-29a Acquired Immunodeficiency Syndrome 16236258 miRNAs expressed in T-cells can repress nef function and thus influence disease progression. other hsa-mir-29b-1 Acquired Immunodeficiency Syndrome 16236258 miRNAs expressed in T-cells can repress nef function and thus influence disease progression. other hsa-mir-181a Hematologic Neoplasms 16249029 "The stress-induced modulation of hematopoietic miR-181a levels through AChE, PKC and PKA cascade(s) suggests using miRNA mimics for diverting the fate of hematopoietic tumor cells towards differentiation and/or apoptosis." other hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 16885332 The finding that essentially all indolent CLLs have lost miR-15a/miR-16-1 expression suggests that this event is the initiating event in the pathogenesis of the indolent form of CLL. other hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 16885332 The finding that essentially all indolent CLLs have lost miR-15a/miR-16-1 expression suggests that this event is the initiating event in the pathogenesis of the indolent form of CLL. other hsa-mir-372 Neoplasms [unspecific] 17028596 "mir-372/373 shown to be oncogenes cooperating with Ras (Voorhoeve et al., 2006)" other hsa-mir-373 Neoplasms [unspecific] 17028596 "mir-372/373 shown to be oncogenes cooperating with Ras (Voorhoeve et al., 2006)" other hsa-mir-17 Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. other hsa-mir-18a Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. other hsa-mir-18b Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. other hsa-mir-19a Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. other hsa-mir-19b-1 Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. other hsa-mir-19b-2 Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. other hsa-mir-20a Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. other hsa-mir-20b Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. other hsa-mir-92a-1 Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. other hsa-mir-92a-2 Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. other hsa-mir-92b Lymphoma 17093929 These data demonstrate that OncomiR-1 accelerates lymphoma and promotes a more disseminated disease. other hsa-mir-32 Viral Infectious Disease 17096367 "The authors found that a cellular miRNA, miR-32, mediated antiviral defense in human cells, and regulated primate foamy virus type I (PFV-1) proliferation." other hsa-mir-17 "Lymphoma, Burkitt" 17135268 "We recently demonstrated that a polycistronic cluster of miRNAs, miR-17-92, is oncogenic in a mouse model for Burkitt's lymphoma." other hsa-mir-18 "Lymphoma, Burkitt" 17135268 "We recently demonstrated that a polycistronic cluster of miRNAs, miR-17-92, is oncogenic in a mouse model for Burkitt's lymphoma." other hsa-mir-19a "Lymphoma, Burkitt" 17135268 "We recently demonstrated that a polycistronic cluster of miRNAs, miR-17-92, is oncogenic in a mouse model for Burkitt's lymphoma." other hsa-mir-19b-1 "Lymphoma, Burkitt" 17135268 "We recently demonstrated that a polycistronic cluster of miRNAs, miR-17-92, is oncogenic in a mouse model for Burkitt's lymphoma." other hsa-mir-20a "Lymphoma, Burkitt" 17135268 "We recently demonstrated that a polycistronic cluster of miRNAs, miR-17-92, is oncogenic in a mouse model for Burkitt's lymphoma." other hsa-mir-92-1 "Lymphoma, Burkitt" 17135268 "We recently demonstrated that a polycistronic cluster of miRNAs, miR-17-92, is oncogenic in a mouse model for Burkitt's lymphoma." other hsa-mir-155 "Lymphoma, Burkitt" 17173072 "Our data provide evidence for two levels of regulation for mature miR-155 expression: one at the transcriptional level involving PKC and NF-kappaB, and one at the processing level. Burkitt lymphoma cells not only express low levels of BIC, but also prevent processing of BIC via an, as yet, unknown mechanism." other hsa-mir-143 Hepatitis C Virus Infection 17188425 "miRNA-143 and -145 levels increase as disease progresses from chronic hepatitis to cirrhosis, suggesting that they may turn on inflammatory or fibrosis related genes and/or turn off tumor suppressor genes." other hsa-mir-145 Hepatitis C Virus Infection 17188425 "miRNA-143 and -145 levels increase as disease progresses from chronic hepatitis to cirrhosis, suggesting that they may turn on inflammatory or fibrosis related genes and/or turn off tumor suppressor genes." other hsa-mir-223 "Leukemia, Promyelocytic, Acute" 17217039 "The activation of both pathways of transcriptional regulation by the myeloid lineage-specific transcription factor C/EBPalpha (CCAAT/enhancer-binding protein-alpha), and posttranscriptional regulation by miR-223 appears essential for granulocytic differentiation and clinical response of acute promyelocytic leukemia (APL) blasts to all-trans retinoic acid (ATRA)." other hsa-mir-155 Vascular Disease [unspecific] 17293455 "As predicted, miRNA-155 transduction greatly reduced both myeloid and erythroid colony formation of normal human HSPCs." other hsa-mir-34a Neuroblastoma 17297439 MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. other hsa-mir-17 Lung Neoplasms 17384677 "In marked contrast, antisense ONs against miR-18a and miR-19a did not exhibit such inhibitory effects, whereas inhibition of miR-92-1 resulted in only modest reduction of cell growth, showing significant distinctions among miRNAs of the miR-17-92 cluster in terms of their roles in cancer cell growth." other hsa-mir-18 Lung Neoplasms 17384677 "In marked contrast, antisense ONs against miR-18a and miR-19a did not exhibit such inhibitory effects, whereas inhibition of miR-92-1 resulted in only modest reduction of cell growth, showing significant distinctions among miRNAs of the miR-17-92 cluster in terms of their roles in cancer cell growth." other hsa-mir-18a Lung Neoplasms 17384677 "In marked contrast, antisense ONs against miR-18a and miR-19a did not exhibit such inhibitory effects, whereas inhibition of miR-92-1 resulted in only modest reduction of cell growth, showing significant distinctions among miRNAs of the miR-17-92 cluster in terms of their roles in cancer cell growth." other hsa-mir-19a Lung Neoplasms 17384677 "In marked contrast, antisense ONs against miR-18a and miR-19a did not exhibit such inhibitory effects, whereas inhibition of miR-92-1 resulted in only modest reduction of cell growth, showing significant distinctions among miRNAs of the miR-17-92 cluster in terms of their roles in cancer cell growth." other hsa-mir-19b-1 Lung Neoplasms 17384677 "In marked contrast, antisense ONs against miR-18a and miR-19a did not exhibit such inhibitory effects, whereas inhibition of miR-92-1 resulted in only modest reduction of cell growth, showing significant distinctions among miRNAs of the miR-17-92 cluster in terms of their roles in cancer cell growth." other hsa-mir-20a Lung Neoplasms 17384677 "In marked contrast, antisense ONs against miR-18a and miR-19a did not exhibit such inhibitory effects, whereas inhibition of miR-92-1 resulted in only modest reduction of cell growth, showing significant distinctions among miRNAs of the miR-17-92 cluster in terms of their roles in cancer cell growth." other hsa-mir-92-1 Lung Neoplasms 17384677 "In marked contrast, antisense ONs against miR-18a and miR-19a did not exhibit such inhibitory effects, whereas inhibition of miR-92-1 resulted in only modest reduction of cell growth, showing significant distinctions among miRNAs of the miR-17-92 cluster in terms of their roles in cancer cell growth." other hsa-mir-1-1 Arrhythmia 17401374 These data strongly indicate that miR-1 is an arrhythmogenic or proarrhythmic factor that is detrimental to the ischemic heart. Delivery of miR-1 into healthy hearts was also arrhythmogenic. other hsa-mir-1-2 Arrhythmia 17401374 These data strongly indicate that miR-1 is an arrhythmogenic or proarrhythmic factor that is detrimental to the ischemic heart. Delivery of miR-1 into healthy hearts was also arrhythmogenic. other hsa-mir-155 Down Syndrome 17468766 "Because miR-155 maps to chromosome 21, Setupathy et al. speculate that miR-155 overexpression in trisomics'a which they confirmed experimentally a accounts for the lower levels of diastolic and systolic blood pressure associated with Down syndrome." other hsa-mir-194-1 Urinary Bladder Cancer 17470785 "The list of miRNAs at or near sites commonly altered in human cancers includes mir-215 and mir-194-1, which are <0.17 kb from D1Mit208, a marker that defines the peak of the colon Scc3 locus on Chr 1. Homologous human miRNAs are located inside the FRA1H at Chr 1q42.1; this fragile site is an HPV16 integration site involved in cervical cancer." other hsa-mir-215 Urinary Bladder Cancer 17470785 "The list of miRNAs at or near sites commonly altered in human cancers includes mir-215 and mir-194-1, which are <0.17 kb from D1Mit208, a marker that defines the peak of the colon Scc3 locus on Chr 1. Homologous human miRNAs are located inside the FRA1H at Chr 1q42.1; this fragile site is an HPV16 integration site involved in cervical cancer." other hsa-mir-21 "Cardiomyopathy, Hypertrophic" 17525252 Modulating miR-21 expression via antisense-mediated depletion (knockdown) had a significant negative effect on cardiomyocyte hypertrophy. other hsa-mir-34a Pancreatic Neoplasms 17540599 "Therefore, it is likely that an important function of miR-34a is the modulation and fine-tuning of the gene expression program initiated by p53." other hsa-let-7a Vascular Disease [unspecific] 17540974 The let-7 family and mir-27b appear to be attractive targets for modulating angiogenesis. other hsa-let-7b Vascular Disease [unspecific] 17540974 The let-7 family and mir-27b appear to be attractive targets for modulating angiogenesis. other hsa-let-7c Vascular Disease [unspecific] 17540974 The let-7 family and mir-27b appear to be attractive targets for modulating angiogenesis. other hsa-let-7d Vascular Disease [unspecific] 17540974 The let-7 family and mir-27b appear to be attractive targets for modulating angiogenesis. other hsa-let-7e Vascular Disease [unspecific] 17540974 The let-7 family and mir-27b appear to be attractive targets for modulating angiogenesis. other hsa-let-7f Vascular Disease [unspecific] 17540974 The let-7 family and mir-27b appear to be attractive targets for modulating angiogenesis. other hsa-let-7g Vascular Disease [unspecific] 17540974 The let-7 family and mir-27b appear to be attractive targets for modulating angiogenesis. other hsa-let-7i Vascular Disease [unspecific] 17540974 The let-7 family and mir-27b appear to be attractive targets for modulating angiogenesis. other hsa-let-7a Neoplasms [unspecific] 17554199 Other p53-induced miRNAs identified here may also have tumor suppressive potential as they are known to suppress the anti-apoptotic factor Bcl2 (miR-15a/16) and the oncogenes RAS and HMGA2 (let-7a). other hsa-mir-17 Lymphoma 17608773 "The c13orf25/miR-17 cluster, which is responsible for 13q31-q32 amplification in malignant lymphoma, contains the microRNA-17-18-19-20-92 polycistron." other hsa-mir-18 Lymphoma 17608773 "The c13orf25/miR-17 cluster, which is responsible for 13q31-q32 amplification in malignant lymphoma, contains the microRNA-17-18-19-20-92 polycistron." other hsa-mir-19a Lymphoma 17608773 "The c13orf25/miR-17 cluster, which is responsible for 13q31-q32 amplification in malignant lymphoma, contains the microRNA-17-18-19-20-92 polycistron." other hsa-mir-19b-1 Lymphoma 17608773 "The c13orf25/miR-17 cluster, which is responsible for 13q31-q32 amplification in malignant lymphoma, contains the microRNA-17-18-19-20-92 polycistron." other hsa-mir-20a Lymphoma 17608773 "The c13orf25/miR-17 cluster, which is responsible for 13q31-q32 amplification in malignant lymphoma, contains the microRNA-17-18-19-20-92 polycistron." other hsa-mir-92-1 Lymphoma 17608773 "The c13orf25/miR-17 cluster, which is responsible for 13q31-q32 amplification in malignant lymphoma, contains the microRNA-17-18-19-20-92 polycistron." other hsa-mir-370 Neoplasms [unspecific] 17621267 "Thus, IL-6 may contribute to tumor growth by modulation of expression of selected miRNAs, such as miR-370. These studies define a mechanism by which inflammation-associated cytokines can epigenetically modulate gene expression and directly contribute to tumor biology." other hsa-mir-16 Leukemia 17683260 "several confirmed miRNA targets appear in our high-confidence set, such as the interactions between miR-92 and the signal transduction gene MAP2K4, as well as the relationship between miR-16 and BCL2, an anti-apoptotic gene which has been implicated in chronic lymphocytic leukemia." other hsa-mir-92 Leukemia 17683260 "several confirmed miRNA targets appear in our high-confidence set, such as the interactions between miR-92 and the signal transduction gene MAP2K4, as well as the relationship between miR-16 and BCL2, an anti-apoptotic gene which has been implicated in chronic lymphocytic leukemia." other hsa-mir-372 Germ Cell And Embryonal Neoplasms 17695719 "we identified miR-372 and miR-373, each permitting proliferation and tumorigenesis of primary human cells that harbor both oncogenic RAS and active wild-type p53." other hsa-mir-373 Germ Cell And Embryonal Neoplasms 17695719 "we identified miR-372 and miR-373, each permitting proliferation and tumorigenesis of primary human cells that harbor both oncogenic RAS and active wild-type p53." other hsa-mir-21 Colon Neoplasms 17702597 "In colon cancer cells, at a clinically relevant concentration,the drug up-regulates or down-regulates in vitro the expression of 19 and 3 miR genes, respectively, by a factor of not less than two-fold. In some instances, 5-FU up-regulates miR genes that are already over-expressed in neoplastic tissues, including, for example, miR-21 that is associated with anti-apoptotic functions characterizing malignant cells. " other hsa-mir-124a Teratocarcinoma 17716626 "Based on these observations, it is suggested that the miR-302 cluster and miR-124a may be useful molecular indicators in the assessmentof degree of undifferentiation and/or differentiation in the course of neuronal differentiation." other hsa-mir-155 Lymphoma 17727326 "Cancer-associated microRNAs can act as both tumour suppressor molecules (e.g., miR-15a and miR-16-1) and have oncogenic properties (e.g., miR-155 and miR-17-92 cluster)." other hsa-mir-15a Lymphoma 17727326 "Cancer-associated microRNAs can act as both tumour suppressor molecules (e.g., miR-15a and miR-16-1) and have oncogenic properties (e.g., miR-155 and miR-17-92 cluster)." other hsa-mir-16-1 Lymphoma 17727326 "Cancer-associated microRNAs can act as both tumour suppressor molecules (e.g., miR-15a and miR-16-1) and have oncogenic properties (e.g., miR-155 and miR-17-92 cluster)." other hsa-mir-17 Lymphoma 17727326 "Cancer-associated microRNAs can act as both tumour suppressor molecules (e.g., miR-15a and miR-16-1) and have oncogenic properties (e.g., miR-155 and miR-17-92 cluster)." other hsa-mir-18 Lymphoma 17727326 "Cancer-associated microRNAs can act as both tumour suppressor molecules (e.g., miR-15a and miR-16-1) and have oncogenic properties (e.g., miR-155 and miR-17-92 cluster)." other hsa-mir-19a Lymphoma 17727326 "Cancer-associated microRNAs can act as both tumour suppressor molecules (e.g., miR-15a and miR-16-1) and have oncogenic properties (e.g., miR-155 and miR-17-92 cluster)." other hsa-mir-19b-1 Lymphoma 17727326 "Cancer-associated microRNAs can act as both tumour suppressor molecules (e.g., miR-15a and miR-16-1) and have oncogenic properties (e.g., miR-155 and miR-17-92 cluster)." other hsa-mir-20a Lymphoma 17727326 "Cancer-associated microRNAs can act as both tumour suppressor molecules (e.g., miR-15a and miR-16-1) and have oncogenic properties (e.g., miR-155 and miR-17-92 cluster)." other hsa-mir-92-1 Lymphoma 17727326 "Cancer-associated microRNAs can act as both tumour suppressor molecules (e.g., miR-15a and miR-16-1) and have oncogenic properties (e.g., miR-155 and miR-17-92 cluster)." other hsa-mir-133b Parkinson Disease 17761882 "Expression of one of these precursor miRNAs, miR-133b, was specifically enriched in the midbrain and deficient in the context of Parkinson's disease patient samples, as determined by ribonuclease (RNase) protection assays, qPCR, and Northern blotting for mature miR-133b." other hsa-mir-1-1 Arrhythmia 17786230 the finding that increasing or decreasing miR-1 expression causes lethal cardiac arrhythmias highlights not only the exquisite sensitivity of the heart to the levels of expression of this miRNA but also poses significant hurdles to the possible therapeutic manipulation of miR-1 levels in the settings of cardiac conduction abnormalities or myocardial repair. other hsa-mir-1-2 Arrhythmia 17786230 the finding that increasing or decreasing miR-1 expression causes lethal cardiac arrhythmias highlights not only the exquisite sensitivity of the heart to the levels of expression of this miRNA but also poses significant hurdles to the possible therapeutic manipulation of miR-1 levels in the settings of cardiac conduction abnormalities or myocardial repair. other hsa-mir-133a-1 Arrhythmia 17786230 "These results suggest an active role for miR-133 in the inhibition of cardiac hypertrophy. Xiao et al. reported miR-133 to play a role in cardiac conductance abnormalities during diabetes by lowering the protein levels of ether-a-go-go§Ò§ÙCrelated gene (ERG), which encodes a key K+ channel (IKr) responsible for rapid delayed rectifier K+ current in cardiac cells." other hsa-mir-133a-1 "Cardiomyopathy, Hypertrophic" 17786230 "These results suggest an active role for miR-133 in the inhibition of cardiac hypertrophy. Xiao et al. reported miR-133 to play a role in cardiac conductance abnormalities during diabetes by lowering the protein levels of ether-a-go-go§Ò§ÙCrelated gene (ERG), which encodes a key K+ channel (IKr) responsible for rapid delayed rectifier K+ current in cardiac cells." other hsa-mir-133a-2 Arrhythmia 17786230 "These results suggest an active role for miR-133 in the inhibition of cardiac hypertrophy. Xiao et al. reported miR-133 to play a role in cardiac conductance abnormalities during diabetes by lowering the protein levels of ether-a-go-go§Ò§ÙCrelated gene (ERG), which encodes a key K+ channel (IKr) responsible for rapid delayed rectifier K+ current in cardiac cells." other hsa-mir-133a-2 "Cardiomyopathy, Hypertrophic" 17786230 "These results suggest an active role for miR-133 in the inhibition of cardiac hypertrophy. Xiao et al. reported miR-133 to play a role in cardiac conductance abnormalities during diabetes by lowering the protein levels of ether-a-go-go§Ò§ÙCrelated gene (ERG), which encodes a key K+ channel (IKr) responsible for rapid delayed rectifier K+ current in cardiac cells." other hsa-mir-208a Endomyocardial Fibrosis 17786230 "Clearly, miR-208 is also essential for expression of the genes involved in cardiac fibrosis and hypertrophic growth." other hsa-mir-208a Hypertrophy 17786230 "Clearly, miR-208 is also essential for expression of the genes involved in cardiac fibrosis and hypertrophic growth." other hsa-mir-21 Heart Diseases [unspecific] 17786230 "Another miRNA consistently induced by cardiac stress, miR-21, appears to function as a regulator of cardiac growth and fetal gene activation in primary cardiomyocytes in vitro although some confusion remains regarding its exact role." other hsa-mir-155 Kaposi Sarcoma 17881434 "Together, these findings indicate that KSHV miR-K12-11 is an ortholog of miR-155." other hsa-mir-150 Leukemia 17923094 "Combining loss- and gain-of-function gene targeting approaches for miR-150 with conditional and partial ablation of c-Myb, we show that miR-150 indeed controls c-Myb expression in vivo in a dose-dependent manner over a narrow range of miRNA and c-Myb concentrations and that this dramatically affects lymphocyte development and response." other hsa-mir-17 "Leukemia, B-Cell" 17940623 "These data suggested a direct involvement of this miRNA cluster in tumorigenesis. The miR-17-92 cluster encompassing six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1." other hsa-mir-18a "Leukemia, B-Cell" 17940623 "These data suggested a direct involvement of this miRNA cluster in tumorigenesis. The miR-17-92 cluster encompassing six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1." other hsa-mir-19a "Leukemia, B-Cell" 17940623 "These data suggested a direct involvement of this miRNA cluster in tumorigenesis. The miR-17-92 cluster encompassing six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1." other hsa-mir-19b-1 "Leukemia, B-Cell" 17940623 "These data suggested a direct involvement of this miRNA cluster in tumorigenesis. The miR-17-92 cluster encompassing six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1." other hsa-mir-20a "Leukemia, B-Cell" 17940623 "These data suggested a direct involvement of this miRNA cluster in tumorigenesis. The miR-17-92 cluster encompassing six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1." other hsa-mir-92a-1 "Leukemia, B-Cell" 17940623 "These data suggested a direct involvement of this miRNA cluster in tumorigenesis. The miR-17-92 cluster encompassing six miRNAs: miR-17, miR-18a, miR-19a, miR-20a, miR-19b-1 and miR-92-1." other hsa-mir-122 Lipid Metabolism Disorder 17965831 Inhibition of miR-122 resulted in decreased levels of cholesterol in the plasma and improved liver function in obese mice. other hsa-mir-155 Kidney Diseases [unspecific] 17965831 miR-155 was shown to decrease the expression of angiotensin II type 1 receptor in human primary fibroblasts [175]. This suggests that miR-155 may regulate a diverse set of physiological functions including fluid homeostasis and renal function. other hsa-mir-155 Lung Neoplasms 17965831 "miR-155 has also been implicated in a number of cancers including Burkitt_s lymphoma, Hodgkin lymphoma and lung cancer." other hsa-mir-155 "Lymphoma, Burkitt" 17965831 "miR-155 has also been implicated in a number of cancers including Burkitt_s lymphoma, Hodgkin lymphoma and lung cancer." other hsa-mir-155 "Lymphoma, Hodgkin" 17965831 "miR-155 has also been implicated in a number of cancers including Burkitt_s lymphoma, Hodgkin lymphoma and lung cancer." other hsa-mir-208a "Cardiomyopathy, Hypertrophic" 17965831 "miR-208 was recently shown to enhance stress-related cardiac muscle growth by up-regulating a contractile protein, bMHC, possibly by repressing translation of thyroid hormone receptor-associated protein 1 (THRAP1)." other hsa-mir-372 Testicular Neoplasms 17965831 miR-372 and miR-373 have been implicated in testicular germ cell tumours. other hsa-mir-373 Testicular Neoplasms 17965831 miR-372 and miR-373 have been implicated in testicular germ cell tumours. other hsa-mir-375 Diabetes Mellitus 17965831 "For instance, miR-375 was shown to directly regulate insulin secretion from pancreatic islet cells. Overexpression of miR-375 led to an enhanced inhibition of insulin exocytosis, whereas anti-sense to miR-375 enhanced insulin secretion by blocking the effects of the miRNA." other hsa-mir-222 Polycythemia Vera 17976518 "Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11." other hsa-mir-339 Polycythemia Vera 17976518 biphasic regulation other hsa-mir-378a Polycythemia Vera 17976518 "Comparative analyses of control and PV EPs suggested increased levels of miR-451, miR-16, miR-21, and miR-26b and decreased levels of miR-150 and miR-221 in PV group, Expression of miR-150 progressively declined with erythroid differentiation, its expression decreased ninefold (p < 0.05) from days 7 to 11." other hsa-mir-17 "Leukemia, B-Cell" 17989227 "the miR-17 cluster (8, 9) synergizes with MYC to induce B cell lymphoma." other hsa-mir-132 Neoplasms [unspecific] 18075311 "In this review, we will discuss the specific roles of miRNA-(miR-)132 and miR-219 in the SCN, as well as a more general outlook on this newly elucidated layer of circadian clock regulation: inducible translation control via miRNAs." other hsa-mir-219 Neoplasms [unspecific] 18075311 "In this review, we will discuss the specific roles of miRNA-(miR-)132 and miR-219 in the SCN, as well as a more general outlook on this newly elucidated layer of circadian clock regulation: inducible translation control via miRNAs." other hsa-let-7g Colon Neoplasms 18172508 Non-coding MicroRNAs hsa-let-7g and hsa-miR-181b are Associated with Chemoresponse to S-1 in Colon Cancer. other hsa-mir-181b Colon Neoplasms 18172508 Non-coding MicroRNAs hsa-let-7g and hsa-miR-181b are Associated with Chemoresponse to S-1 in Colon Cancer. other hsa-let-7c Colon Neoplasms 18188765 "Let-7C was clearly present in lung, prostate, and colon cancers but undetectable in ovary and thyroid cancer samples" other hsa-mir-155 Kaposi Sarcoma 18191785 "Two new papers provide strong evidence that a KSHV-encoded microRNA and mir-155 share a common set of mRNA targets and binding sites, implying a possible link between viral- and non-viral-mediated tumorigenesis." other hsa-mir-373 Prostate Neoplasms 18193036 "Taken together, our findings indicate that miRNAs are involved in tumour migration and invasion, and implicate miR-373 and miR-520c as metastasis-promoting miRNAs." other hsa-mir-214 Ovarian Neoplasms 18199536 These findings indicate that deregulation of miRNAs is a recurrent event in human ovarian cancer and that miR-214 induces cell survival and cisplatin resistance primarily through targeting the PTEN/Akt pathway. other hsa-mir-10b Neoplasms [unspecific] 18256538 pro-metastatic other hsa-mir-181a Inflammation 18291670 "MiRNAs are implicated in establishing and maintaining the cell fate of immune cells (e.g. miR-181a and miR-223), and they are involved in innate immunity by regulating Toll-like receptor signaling and ensuing cytokine response (e.g. miR-146)." other hsa-mir-203 Inflammation 18291670 "MiRNAs are implicated in establishing and maintaining the cell fate of immune cells (e.g. miR-181a and miR-223), and they are involved in innate immunity by regulating Toll-like receptor signaling and ensuing cytokine response (e.g. miR-146)." other hsa-mir-137 Melanoma 18316599 MicroRNA-137 targets microphthalmia-associated transcription factor in melanoma cell lines. other hsa-mir-17 Lymphoma 18329372 These results provide key insights into the physiologic functions of this family of microRNAs and suggest a link between the oncogenic properties of miR-17 approximately 92 and its functionsduring B lymphopoiesis and lung development. other hsa-mir-18 Lymphoma 18329372 These results provide key insights into the physiologic functions of this family of microRNAs and suggest a link between the oncogenic properties of miR-17 approximately 92 and its functionsduring B lymphopoiesis and lung development. other hsa-mir-19a Lymphoma 18329372 These results provide key insights into the physiologic functions of this family of microRNAs and suggest a link between the oncogenic properties of miR-17 approximately 92 and its functionsduring B lymphopoiesis and lung development. other hsa-mir-19b-1 Lymphoma 18329372 These results provide key insights into the physiologic functions of this family of microRNAs and suggest a link between the oncogenic properties of miR-17 approximately 92 and its functionsduring B lymphopoiesis and lung development. other hsa-mir-20a Lymphoma 18329372 These results provide key insights into the physiologic functions of this family of microRNAs and suggest a link between the oncogenic properties of miR-17 approximately 92 and its functionsduring B lymphopoiesis and lung development. other hsa-mir-92-1 Lymphoma 18329372 These results provide key insights into the physiologic functions of this family of microRNAs and suggest a link between the oncogenic properties of miR-17 approximately 92 and its functionsduring B lymphopoiesis and lung development. other hsa-mir-146a "Lymphoma, Burkitt" 18347435 induced by EBV-encoded latent membrane protein 1 (LMP1) other hsa-mir-155 "Lymphoma, Burkitt" 18347435 induced by EBV-encoded latent membrane protein 1 (LMP1) other hsa-mir-155 "Lymphoma, Burkitt" 18354490 process BIC other hsa-mir-206 Vascular Hypertrophy 18381085 The review is also intended to serve as a comprehensive resource for miR-206 with the hope of encouraging further research on the role of miR-206 in skeletal muscle. other hsa-mir-200a Neoplasms [unspecific] 18381893 the epithelial-to-mesenchymal transition other hsa-mir-200b Neoplasms [unspecific] 18381893 the epithelial-to-mesenchymal transition other hsa-mir-200c Neoplasms [unspecific] 18381893 the epithelial-to-mesenchymal transition other hsa-mir-146b Inflammation 18390754 "Overall, these studies indicate that rapid increase in miRNA-146a expression provides a novel mechanism for the negative regulation of severe inflammation during the innate immune response." other hsa-mir-146a Osteoarthritis 18438844 This study shows that miR-146 is expressed in RA synovial tissue and that its expression is induced by stimulation with TNFalpha and IL-1beta. Further studies are required to elucidate the function of miR-146 in these tissues. other hsa-mir-100 Ovarian Neoplasms 18451233 normal other hsa-mir-125a Ovarian Neoplasms 18451233 normal other hsa-mir-145 Ovarian Neoplasms 18451233 normal other hsa-mir-21 Ovarian Neoplasms 18451233 normal other hsa-mir-99a Ovarian Neoplasms 18451233 normal other hsa-mir-7 Glioblastoma 18483236 microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. other hsa-mir-141 "Carcinoma, Rectal" 18483486 "Here, we report that ZEB1 directly suppresses transcription of microRNA-200 family members miR-141 and miR-200c, which strongly activate epithelial differentiation in pancreatic, colorectal and breast cancer cells." other hsa-mir-200c "Carcinoma, Rectal" 18483486 "Here, we report that ZEB1 directly suppresses transcription of microRNA-200 family members miR-141 and miR-200c, which strongly activate epithelial differentiation in pancreatic, colorectal and breast cancer cells." other hsa-mir-150 Leukemia 18536574 "Using animal models engineered to overexpress miR-150, miR-17 approximately 92 and miR-155 or to be deficient for miR-223, miR-155 and miR-17 approximately 92 expression, several groups have now shown that miRNAs are critical for B-lymphocyte development (miR-150 and miR-17 approximately 92), granulopoiesis (miR-223), immune function (miR-155) and B-lymphoproliferative disorders (miR-155 and miR-17 approximately 92)." other hsa-mir-155 Leukemia 18536574 "Using animal models engineered to overexpress miR-150, miR-17 approximately 92 and miR-155 or to be deficient for miR-223, miR-155 and miR-17 approximately 92 expression, several groups have now shown that miRNAs are critical for B-lymphocyte development (miR-150 and miR-17 approximately 92), granulopoiesis (miR-223), immune function (miR-155) and B-lymphoproliferative disorders (miR-155 and miR-17 approximately 92)." other hsa-mir-17 Leukemia 18536574 "Using animal models engineered to overexpress miR-150, miR-17 approximately 92 and miR-155 or to be deficient for miR-223, miR-155 and miR-17 approximately 92 expression, several groups have now shown that miRNAs are critical for B-lymphocyte development (miR-150 and miR-17 approximately 92), granulopoiesis (miR-223), immune function (miR-155) and B-lymphoproliferative disorders (miR-155 and miR-17 approximately 92)." other hsa-mir-18 Leukemia 18536574 "Using animal models engineered to overexpress miR-150, miR-17 approximately 92 and miR-155 or to be deficient for miR-223, miR-155 and miR-17 approximately 92 expression, several groups have now shown that miRNAs are critical for B-lymphocyte development (miR-150 and miR-17 approximately 92), granulopoiesis (miR-223), immune function (miR-155) and B-lymphoproliferative disorders (miR-155 and miR-17 approximately 92)." other hsa-mir-19a Leukemia 18536574 "Using animal models engineered to overexpress miR-150, miR-17 approximately 92 and miR-155 or to be deficient for miR-223, miR-155 and miR-17 approximately 92 expression, several groups have now shown that miRNAs are critical for B-lymphocyte development (miR-150 and miR-17 approximately 92), granulopoiesis (miR-223), immune function (miR-155) and B-lymphoproliferative disorders (miR-155 and miR-17 approximately 92)." other hsa-mir-19b-1 Leukemia 18536574 "Using animal models engineered to overexpress miR-150, miR-17 approximately 92 and miR-155 or to be deficient for miR-223, miR-155 and miR-17 approximately 92 expression, several groups have now shown that miRNAs are critical for B-lymphocyte development (miR-150 and miR-17 approximately 92), granulopoiesis (miR-223), immune function (miR-155) and B-lymphoproliferative disorders (miR-155 and miR-17 approximately 92)." other hsa-mir-20a Leukemia 18536574 "Using animal models engineered to overexpress miR-150, miR-17 approximately 92 and miR-155 or to be deficient for miR-223, miR-155 and miR-17 approximately 92 expression, several groups have now shown that miRNAs are critical for B-lymphocyte development (miR-150 and miR-17 approximately 92), granulopoiesis (miR-223), immune function (miR-155) and B-lymphoproliferative disorders (miR-155 and miR-17 approximately 92)." other hsa-mir-223 Leukemia 18536574 "Using animal models engineered to overexpress miR-150, miR-17 approximately 92 and miR-155 or to be deficient for miR-223, miR-155 and miR-17 approximately 92 expression, several groups have now shown that miRNAs are critical for B-lymphocyte development (miR-150 and miR-17 approximately 92), granulopoiesis (miR-223), immune function (miR-155) and B-lymphoproliferative disorders (miR-155 and miR-17 approximately 92)." other hsa-mir-92-1 Leukemia 18536574 "Using animal models engineered to overexpress miR-150, miR-17 approximately 92 and miR-155 or to be deficient for miR-223, miR-155 and miR-17 approximately 92 expression, several groups have now shown that miRNAs are critical for B-lymphocyte development (miR-150 and miR-17 approximately 92), granulopoiesis (miR-223), immune function (miR-155) and B-lymphoproliferative disorders (miR-155 and miR-17 approximately 92)." other hsa-let-7f Vascular Disease [unspecific] 18550634 "Meanwhile, a few specific miRNAs that regulate endothelial cell functions and angiogenesis have been described. Let7-f, miR-27b, and mir-130a were identified as pro-angiogenic miRNAs" other hsa-mir-130a Vascular Disease [unspecific] 18550634 "Meanwhile, a few specific miRNAs that regulate endothelial cell functions and angiogenesis have been described. Let7-f, miR-27b, and mir-130a were identified as pro-angiogenic miRNAs" other hsa-mir-27b Vascular Disease [unspecific] 18550634 "Meanwhile, a few specific miRNAs that regulate endothelial cell functions and angiogenesis have been described. Let7-f, miR-27b, and mir-130a were identified as pro-angiogenic miRNAs" other hsa-mir-122 Hepatitis C Virus Infection 18550664 miR-122: Liver-specific microRNA miR-122 enhances the replication of hepatitis C virus in nonhepatic cells other hsa-mir-198 Schizophrenia 18552348 "Human microRNAs (Hsa-mir-198 and Hsa-mir-206) are predicted to bind to influenza, rubella, or poliovirus genes. Certain genes associated with schizophrenia, including those also concerned with neurophysiology, are intimately related to the life cycles of the pathogens implicated in the disease." other hsa-mir-206 Schizophrenia 18552348 "Human microRNAs (Hsa-mir-198 and Hsa-mir-206) are predicted to bind to influenza, rubella, or poliovirus genes. Certain genes associated with schizophrenia, including those also concerned with neurophysiology, are intimately related to the life cycles of the pathogens implicated in the disease." other hsa-mir-223 "Carcinoma, Hepatocellular" 18555017 miR-223: MicroRNA-223 is commonly reproessed in hepatocellular carcinoma and potentiates expression of Stathmin1 other hsa-let-7a-1 Neoplasms [unspecific] 18560417 let-7a: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication other hsa-let-7a-2 Neoplasms [unspecific] 18560417 let-7a: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication other hsa-let-7a-3 Neoplasms [unspecific] 18560417 let-7a: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication other hsa-let-7b Neoplasms [unspecific] 18560417 let-7b: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication other hsa-let-7c Neoplasms [unspecific] 18560417 let-7c: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication other hsa-let-7d Neoplasms [unspecific] 18560417 let-7d: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication other hsa-let-7e Neoplasms [unspecific] 18560417 let-7e: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication other hsa-let-7f-1 Neoplasms [unspecific] 18560417 let-7f: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication other hsa-let-7f-2 Neoplasms [unspecific] 18560417 let-7f: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication other hsa-let-7g Neoplasms [unspecific] 18560417 let-7g: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication other hsa-let-7i Neoplasms [unspecific] 18560417 let-7i: A let-7 MicroRNA-sensitive vesicular stomatitis virus demonstrates tumor-specific replication other hsa-mir-124-1 Glioblastoma 18577219 miR-124: miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells other hsa-mir-124-2 Glioblastoma 18577219 miR-124: miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells other hsa-mir-124-3 Glioblastoma 18577219 miR-124: miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells other hsa-mir-137 Glioblastoma 18577219 miR-137: miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells other hsa-mir-100 Heart Failure 18582896 "To pursue the observation that changes in expression levels of individual miRNAs are functionally relevant, microRNA mimics and inhibitors to miR-92, miR-100 and miR-133b were expressed in primary cultures of neonatal rat cardiac myocytes." other hsa-mir-133b Heart Failure 18582896 "To pursue the observation that changes in expression levels of individual miRNAs are functionally relevant, microRNA mimics and inhibitors to miR-92, miR-100 and miR-133b were expressed in primary cultures of neonatal rat cardiac myocytes." other hsa-mir-92 Heart Failure 18582896 "To pursue the observation that changes in expression levels of individual miRNAs are functionally relevant, microRNA mimics and inhibitors to miR-92, miR-100 and miR-133b were expressed in primary cultures of neonatal rat cardiac myocytes." other hsa-mir-126 Lung Neoplasms 18602365 miR-126: MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines other hsa-mir-451a Breast Neoplasms 18645025 miR-451: Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin other hsa-mir-126 Colon Neoplasms 18663744 miR-126: miR-126 suppresses the growth of neoplastic cells other hsa-mir-150 Leukemia 18667440 Our findings suggest that c-Myb is an evolutionally conserved target of miR-150 and miR-150/c-Myb interaction is important for embryonic development and possibly oncogenesis. other hsa-mir-145 Colon Neoplasms 18676867 miR-145: miR-145 potently suppressed growth of three different colon carcinoma cell lines other hsa-mir-498 Colon Neoplasms 18676867 miR-498: correlated with the probability of recurrence-free survival other hsa-mir-126 Myocardial Infarction 18694565 We show that an endothelial cell-restricted microRNA (miR-126) mediates developmental angiogenesis in vivo. other hsa-mir-17 Neoplasms [unspecific] 18700987 miR-17-5p: The miR-17-5p microRNA is able to act as both an oncogene and a tumor suppressor in different cellular contexts other hsa-mir-181a-2 Glioma 18710654 miR-181a: mir suppressor other hsa-mir-181b-1 Glioma 18710654 miR-181b: mir suppressor other hsa-mir-181b-2 Glioma 18710654 miR-181b: mir suppressor other hsa-mir-302a Skin Neoplasms 18755840 miR-302: Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state other hsa-mir-302b Skin Neoplasms 18755840 miR-302: Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state other hsa-mir-302c Skin Neoplasms 18755840 miR-302: Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state other hsa-mir-302d Skin Neoplasms 18755840 miR-302: Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state other hsa-mir-210 Breast Neoplasms 18755890 "miR-210: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer" other hsa-mir-516a-1 Breast Neoplasms 18755890 "miR-516-3p: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer" other hsa-mir-516a-2 Breast Neoplasms 18755890 "miR-516-3p: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer" other hsa-mir-516b-1 Breast Neoplasms 18755890 "miR-516-3p: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer" other hsa-mir-516b-2 Breast Neoplasms 18755890 "miR-516-3p: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer" other hsa-mir-7-1 Breast Neoplasms 18755890 "miR-7: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer" other hsa-mir-7-2 Breast Neoplasms 18755890 "miR-7: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer" other hsa-mir-7-3 Breast Neoplasms 18755890 "miR-7: associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer" other hsa-mir-221 Glioblastoma 18759060 Up-regulation of micro-RNA-221 (miRNA-221; chr Xp11.3) and caspase-3 accompanies down-regulation of the survivin-1 homolog BIRC1 (NAIP) in glioblastoma multiforme (GBM). other hsa-mir-27a Gastric Neoplasms 18789835 miR-27a: MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin other hsa-mir-221 Breast Neoplasms 18790736 miR-221: MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer other hsa-mir-222 Breast Neoplasms 18790736 miR-222: MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer other hsa-mir-21 Gastric Neoplasms 18794849 miR-21: miR-21 plays a pivotal role in gastric cancer pathogenesis and progression other hsa-mir-34b "Lymphoma, Burkitt" 18802929 These results indicate for the first time that hsa-mir-34b may influence c-Myc expression in Burkitt lymphoma as the more common aberrant control exercised by the immunoglobulin enhancer locus. other hsa-mir-34a Gastric Neoplasms 18803879 miR-34: tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres other hsa-mir-34b Gastric Neoplasms 18803879 miR-34: tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres other hsa-mir-34c Gastric Neoplasms 18803879 miR-34: tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres other hsa-mir-21 Glioblastoma 18829576 miR-21: MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma other hsa-mir-126 "Leukemia, Myeloid, Acute" 18832181 "miR-126: discriminate CBF, t(15;17), and MLL-rearrangement AMLs" other hsa-mir-17 "Leukemia, Myeloid, Acute" 18832181 "miR-17-5p: discriminate CBF, t(15;17), and MLL-rearrangement AMLs" other hsa-mir-20a "Leukemia, Myeloid, Acute" 18832181 "miR-20a: discriminate CBF, t(15;17), and MLL-rearrangement AMLs" other hsa-mir-224 "Leukemia, Myeloid, Acute" 18832181 "miR-224: discriminate CBF, t(15;17), and MLL-rearrangement AMLs" other hsa-mir-382 "Leukemia, Myeloid, Acute" 18832181 "miR-382: discriminate CBF, t(15;17), and MLL-rearrangement AMLs" other hsa-mir-183 Lung Neoplasms 18840437 miR-183: a potential metastasis-inhibitor other hsa-mir-125b Psoriasis 18853072 "Recent findings report their involvement in hair follicle morphogenesis (ablation of miRNAs from keratinocytes causes several defects, such as evagination instead of invagination), in psoriasis (skin-specific expression of miR-203 and psoriasisspecific expression of miR-146a, miR-21 and miR-125b in the skin)" other hsa-mir-146a Psoriasis 18853072 "Recent findings report their involvement in hair follicle morphogenesis (ablation of miRNAs from keratinocytes causes several defects, such as evagination instead of invagination), in psoriasis (skin-specific expression of miR-203 and psoriasisspecific expression of miR-146a, miR-21 and miR-125b in the skin)" other hsa-mir-203 Psoriasis 18853072 "Recent findings report their involvement in hair follicle morphogenesis (ablation of miRNAs from keratinocytes causes several defects, such as evagination instead of invagination), in psoriasis (skin-specific expression of miR-203 and psoriasisspecific expression of miR-146a, miR-21 and miR-125b in the skin)" other hsa-mir-21 Psoriasis 18853072 "Recent findings report their involvement in hair follicle morphogenesis (ablation of miRNAs from keratinocytes causes several defects, such as evagination instead of invagination), in psoriasis (skin-specific expression of miR-203 and psoriasisspecific expression of miR-146a, miR-21 and miR-125b in the skin)" other hsa-mir-106b Neoplasms [unspecific] 18922889 miR-106b: key modulators of TGFbeta signaling other hsa-mir-17 Neoplasms [unspecific] 18922889 miR-17: key modulators of TGFbeta signaling other hsa-mir-18a Neoplasms [unspecific] 18922889 miR-18a: key modulators of TGFbeta signaling other hsa-mir-19a Neoplasms [unspecific] 18922889 miR-19a: key modulators of TGFbeta signaling other hsa-mir-19b-1 Neoplasms [unspecific] 18922889 miR-19b: key modulators of TGFbeta signaling other hsa-mir-19b-2 Neoplasms [unspecific] 18922889 miR-19b: key modulators of TGFbeta signaling other hsa-mir-20a Neoplasms [unspecific] 18922889 miR-20a: key modulators of TGFbeta signaling other hsa-mir-25 Neoplasms [unspecific] 18922889 miR-25: key modulators of TGFbeta signaling other hsa-mir-92a-1 Neoplasms [unspecific] 18922889 miR-92a: key modulators of TGFbeta signaling other hsa-mir-92a-2 Neoplasms [unspecific] 18922889 miR-92a: key modulators of TGFbeta signaling other hsa-mir-93 Neoplasms [unspecific] 18922889 miR-93: key modulators of TGFbeta signaling other hsa-mir-141 Neoplasms [unspecific] 18927505 Several recent studies have identified the miR-200 family and miR-205 as key regulators of EMT and enforcers of the epithelial phenotype. other hsa-mir-200a Neoplasms [unspecific] 18927505 Several recent studies have identified the miR-200 family and miR-205 as key regulators of EMT and enforcers of the epithelial phenotype. other hsa-mir-200b Neoplasms [unspecific] 18927505 Several recent studies have identified the miR-200 family and miR-205 as key regulators of EMT and enforcers of the epithelial phenotype. other hsa-mir-200c Neoplasms [unspecific] 18927505 Several recent studies have identified the miR-200 family and miR-205 as key regulators of EMT and enforcers of the epithelial phenotype. other hsa-mir-205 Neoplasms [unspecific] 18927505 Several recent studies have identified the miR-200 family and miR-205 as key regulators of EMT and enforcers of the epithelial phenotype. other hsa-mir-429 Neoplasms [unspecific] 18927505 Several recent studies have identified the miR-200 family and miR-205 as key regulators of EMT and enforcers of the epithelial phenotype. other hsa-mir-21 Breast Neoplasms 18932017 miR-21: High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-beta1 other hsa-mir-125b-1 "Leukemia, Myeloid, Acute" 18936236 miR-125b-1: Myeloid cell differentiation arrest by miR-125b-1 other hsa-mir-21 Kaposi Sarcoma 18971265 "Therefore, K15M may contribute to KSHV-mediated tumor metastasis and angiogenesis via regulation of miR-21 and miR-31, which we show here for the first time to be a specific regulator of cell migration." other hsa-mir-31 Kaposi Sarcoma 18971265 "Therefore, K15M may contribute to KSHV-mediated tumor metastasis and angiogenesis via regulation of miR-21 and miR-31, which we show here for the first time to be a specific regulator of cell migration." other hsa-mir-125a Medulloblastoma 18973228 miR-125a: promote growth arrest and apoptosis of MB cells other hsa-mir-9-1 Medulloblastoma 18973228 miR-9: promote growth arrest and apoptosis of MB cells other hsa-mir-9-2 Medulloblastoma 18973228 miR-9: promote growth arrest and apoptosis of MB cells other hsa-mir-9-3 Medulloblastoma 18973228 miR-9: promote growth arrest and apoptosis of MB cells other hsa-mir-106a Gastric Neoplasms 18996190 miR-106a: oncogenic activity other hsa-mir-34a "Carcinoma, Hepatocellular" 19006648 miR-34a: miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells other hsa-mir-133a-1 Chronic Heart Failure 19015276 microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart other hsa-mir-133a-2 Chronic Heart Failure 19015276 microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart other hsa-mir-122 Hepatitis C Virus Infection 19020517 miR-122: microRNA-122 stimulates translation of hepatitis C virus RNA other hsa-mir-18a "Carcinoma, Hepatocellular" 19027010 "miR-18a: prevents estrogen receptor-alpha expression, promoting proliferation" other hsa-mir-453 Breast Neoplasms 19028706 "In contrast, the T allele attenuates the binding of miR-453, which might lead to a reduced miRNA-mediated ESR1 repression, in consequence higher ESR1 protein levels and an increased breast cancer risk." other hsa-mir-21 Cardiomyopathy 19043405 miR-21: MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts other hsa-mir-21 Cardiovascular Diseases [unspecific] 19043405 MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts other hsa-mir-133a Heart Failure 19056878 "It will be interesting to see, if miR-133a is also involved in human heart diseases, especially VSD and dilated cardiomyopathy." other hsa-mir-21 Neoplasms [unspecific] 19073608 miR-21: coordinately regulate EGFR signaling in multiple human cancer cell types other hsa-mir-7-1 Neoplasms [unspecific] 19073608 miR-7: coordinately regulate EGFR signaling in multiple human cancer cell types other hsa-mir-7-2 Neoplasms [unspecific] 19073608 miR-7: coordinately regulate EGFR signaling in multiple human cancer cell types other hsa-mir-7-3 Neoplasms [unspecific] 19073608 miR-7: coordinately regulate EGFR signaling in multiple human cancer cell types other hsa-mir-122 Chronic Hepatitis C 19085952 "Moreover, CD56(+) T SN treatment inhibited the expression of HCV-supportive micro RNA (miRNA)-122 and enhanced the levels of anti-HCV miRNA-196a in human hepatocytes." other hsa-mir-196a Chronic Hepatitis C 19085952 "Moreover, CD56(+) T SN treatment inhibited the expression of HCV-supportive micro RNA (miRNA)-122 and enhanced the levels of anti-HCV miRNA-196a in human hepatocytes." other hsa-mir-133a-1 Cardiomegaly 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling other hsa-mir-133a-1 Heart Failure 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling other hsa-mir-133a-2 Cardiomegaly 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling other hsa-mir-133a-2 Heart Failure 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling other hsa-mir-133b Cardiomegaly 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling other hsa-mir-133b Heart Failure 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling other hsa-mir-30a Cardiomegaly 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling other hsa-mir-30a Heart Failure 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling other hsa-mir-30b Cardiomegaly 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling other hsa-mir-30b Heart Failure 19096030 miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling other hsa-mir-29a Acquired Immunodeficiency Syndrome 19102781 miR-29a: Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication other hsa-mir-520b Neoplasms [unspecific] 19109132 "miR-520b: miR-520b was induced by IFN-gamma, leading to a reduction in MICA surface protein levels" other hsa-mir-106b Alzheimer Disease 19110058 miR-106b: endogenous regulators of APP expression other hsa-mir-17 Alzheimer Disease 19110058 miR-17-5p: endogenous regulators of APP expression other hsa-mir-20a Alzheimer Disease 19110058 miR-20a: endogenous regulators of APP expression other hsa-mir-200c Pancreatic Neoplasms 19112422 Expression of microRNA was determined with microRNA array. Expression of miR-200c and miR-21 was detected by Northern blotting. other hsa-mir-195 Schizophrenia 19121517 "Using a postmortem case-control design, the association between BDNF protein, NPY/SST/PV mRNAs, and two BDNF-regulating microRNAs (miR-195 and miR-30a-5p) was determined in samples from the PFC of 20 schizophrenia and 20 control subjects." other hsa-mir-30a Schizophrenia 19121517 "Using a postmortem case-control design, the association between BDNF protein, NPY/SST/PV mRNAs, and two BDNF-regulating microRNAs (miR-195 and miR-30a-5p) was determined in samples from the PFC of 20 schizophrenia and 20 control subjects." other hsa-mir-122 Hepatitis C Virus Infection 19122656 miR-122: Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy other hsa-mir-101-1 Colon Neoplasms 19133256 miR-101: MiR-101 downregulation is involved in cyclooxygenase-2 overexpression other hsa-mir-101-2 Colon Neoplasms 19133256 miR-101: MiR-101 downregulation is involved in cyclooxygenase-2 overexpression other hsa-let-7a-1 Pituitary Neoplasms 19136928 let-7a: Overexpression of HMGA2 relates to reduction of the let-7 other hsa-let-7a-2 Pituitary Neoplasms 19136928 let-7a: Overexpression of HMGA2 relates to reduction of the let-7 other hsa-let-7a-3 Pituitary Neoplasms 19136928 let-7a: Overexpression of HMGA2 relates to reduction of the let-7 other hsa-let-7b Pituitary Neoplasms 19136928 let-7b: Overexpression of HMGA2 relates to reduction of the let-7 other hsa-let-7c Pituitary Neoplasms 19136928 let-7c: Overexpression of HMGA2 relates to reduction of the let-7 other hsa-let-7d Pituitary Neoplasms 19136928 let-7d: Overexpression of HMGA2 relates to reduction of the let-7 other hsa-let-7e Pituitary Neoplasms 19136928 let-7e: Overexpression of HMGA2 relates to reduction of the let-7 other hsa-let-7f-1 Pituitary Neoplasms 19136928 let-7f: Overexpression of HMGA2 relates to reduction of the let-7 other hsa-let-7f-2 Pituitary Neoplasms 19136928 let-7f: Overexpression of HMGA2 relates to reduction of the let-7 other hsa-let-7g Pituitary Neoplasms 19136928 let-7g: Overexpression of HMGA2 relates to reduction of the let-7 other hsa-let-7i Pituitary Neoplasms 19136928 let-7i: Overexpression of HMGA2 relates to reduction of the let-7 other hsa-mir-199a-1 Hepatitis C Virus Infection 19144437 miR-199a: Regulation of the hepatitis C virus genome replication other hsa-mir-199a-2 Hepatitis C Virus Infection 19144437 miR-199a: Regulation of the hepatitis C virus genome replication other hsa-mir-21 Myocardial Infarction 19147588 miR-21: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue other hsa-mir-223 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 19148136 miR-223: regulated by Glucocorticoids (GCs) other hsa-mir-198 Acquired Immunodeficiency Syndrome 19148268 miR-198: miR-198 inhibits HIV-1 gene expression and replication in monocytes other hsa-mir-27a Gastric Neoplasms 19148490 miR-27a: There was a correlation between mir-27a and lymph node metastasis other hsa-mir-1 Heart Failure 19149547 "miR-133 and miR-1 are specifically expressed in cardiac and skeletal muscle and control myogenesis, cardiac development, cardiac performance and cardiomyocyte hypertrophy (mainly by tuning transcription factors and other growth-related targets)." other hsa-mir-133 Heart Failure 19149547 "miR-133 and miR-1 are specifically expressed in cardiac and skeletal muscle and control myogenesis, cardiac development, cardiac performance and cardiomyocyte hypertrophy (mainly by tuning transcription factors and other growth-related targets)." other hsa-mir-34a "Leukemia, Promyelocytic, Acute" 19151778 miR-34: that enforced expression of miR-342 in APL cells stimulated ATRA-induced differentiation other hsa-mir-34b "Leukemia, Promyelocytic, Acute" 19151778 miR-34: that enforced expression of miR-342 in APL cells stimulated ATRA-induced differentiation other hsa-mir-34c "Leukemia, Promyelocytic, Acute" 19151778 miR-34: that enforced expression of miR-342 in APL cells stimulated ATRA-induced differentiation other hsa-mir-101-1 "Carcinoma, Hepatocellular" 19155302 miR-101: a tumor suppressor other hsa-mir-101-2 "Carcinoma, Hepatocellular" 19155302 miR-101: a tumor suppressor other hsa-mir-143 Urinary Bladder Cancer 19157460 miR-143: a tumor suppressor other hsa-mir-21 Brain Neoplasms 19175699 "Since its identification 3 years ago as the miRNA most commonly and strongly up-regulated in human brain tumour glioblastoma [1], miR-21 has attracted the attention of researchers in various fields" other hsa-mir-143 Obesity 19188425 Our results provide the first experimental evidence for miR-103 function in adipose biology. other hsa-mir-196b Leukemia 19188669 miR-196b: MLL normally regulates expression of mir-196b other hsa-mir-143 Barrett Esophagus 19190970 miR-143: significantly higher other hsa-mir-219 Nervous System Diseases [unspecific] 19196972 miR-219: MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction other hsa-mir-17 Medulloblastoma 19196975 miR-17: collaborates with the Sonic Hedgehog pathway other hsa-mir-18a Medulloblastoma 19196975 miR-18a: collaborates with the Sonic Hedgehog pathway other hsa-mir-19a Medulloblastoma 19196975 miR-19a: collaborates with the Sonic Hedgehog pathway other hsa-mir-19b-1 Medulloblastoma 19196975 miR-19b: collaborates with the Sonic Hedgehog pathway other hsa-mir-19b-2 Medulloblastoma 19196975 miR-19b: collaborates with the Sonic Hedgehog pathway other hsa-mir-20a Medulloblastoma 19196975 miR-20a: collaborates with the Sonic Hedgehog pathway other hsa-mir-92a-1 Medulloblastoma 19196975 miR-92a: collaborates with the Sonic Hedgehog pathway other hsa-mir-92a-2 Medulloblastoma 19196975 miR-92a: collaborates with the Sonic Hedgehog pathway other hsa-mir-21 Liver Cirrhosis 19203462 miR-21: n/a other hsa-mir-106a Lung Neoplasms 19209007 "High levels of miR-106a were associated with small-cell lung cancer (p = 0.031), and high levels of miR-19a with advanced NSCLC (p = 0.008)." other hsa-let-7a-1 Neoplasms [unspecific] 19221491 let-7a: guardians against pluripotency and cancer progression other hsa-let-7a-2 Neoplasms [unspecific] 19221491 let-7a: guardians against pluripotency and cancer progression other hsa-let-7a-3 Neoplasms [unspecific] 19221491 let-7a: guardians against pluripotency and cancer progression other hsa-let-7b Neoplasms [unspecific] 19221491 let-7b: guardians against pluripotency and cancer progression other hsa-let-7c Neoplasms [unspecific] 19221491 let-7c: guardians against pluripotency and cancer progression other hsa-let-7d Neoplasms [unspecific] 19221491 let-7d: guardians against pluripotency and cancer progression other hsa-let-7e Neoplasms [unspecific] 19221491 let-7e: guardians against pluripotency and cancer progression other hsa-let-7f-1 Neoplasms [unspecific] 19221491 let-7f: guardians against pluripotency and cancer progression other hsa-let-7f-2 Neoplasms [unspecific] 19221491 let-7f: guardians against pluripotency and cancer progression other hsa-let-7g Neoplasms [unspecific] 19221491 let-7g: guardians against pluripotency and cancer progression other hsa-let-7i Neoplasms [unspecific] 19221491 let-7i: guardians against pluripotency and cancer progression other hsa-mir-200a Neoplasms [unspecific] 19221491 miR-200: guardians against pluripotency and cancer progression other hsa-mir-200b Neoplasms [unspecific] 19221491 miR-200: guardians against pluripotency and cancer progression other hsa-mir-200c Neoplasms [unspecific] 19221491 miR-200: guardians against pluripotency and cancer progression other hsa-mir-126 Lung Neoplasms 19223090 miR-126: inhibit the growth other hsa-mir-205 Prostate Neoplasms 19244118 miR-205: miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon other hsa-mir-29a Breast Neoplasms 19247375 "miR-29a: miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis. Therefore, miRNAs can act as either oncogenes or tumour suppressors, depending on the context" other hsa-mir-34a Urinary Bladder Cancer 19258450 miR-34a: Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6 other hsa-mir-182 Prostate Neoplasms 19267923 miR-182: with high analytical sensitivity and specificity other hsa-mir-21 Prostate Neoplasms 19267923 miR-21: with high analytical sensitivity and specificity other hsa-mir-221 Prostate Neoplasms 19267923 miR-221: with high analytical sensitivity and specificity other hsa-mir-222 Prostate Neoplasms 19267923 miR-222: with high analytical sensitivity and specificity other hsa-mir-16-1 Neoplasms [unspecific] 19269153 miR-16: can be upregulated by Epigallocatechin gallate other hsa-mir-16-2 Neoplasms [unspecific] 19269153 miR-16: can be upregulated by Epigallocatechin gallate other hsa-mir-205 Lung Neoplasms 19273703 miR-205: hsa-miR-205 as a highly specific marker for squamous cell lung carcinoma other hsa-mir-196b Neutropenia 19278956 miR-196b: regulated by Gfi1 other hsa-mir-21 Neutropenia 19278956 miR-21: regulated by Gfi1 other hsa-mir-101-1 Prostate Neoplasms 19285253 miR-101: decrease of miR-101 leads to the overexpression of EZH2 other hsa-mir-101-2 Prostate Neoplasms 19285253 miR-101: decrease of miR-101 leads to the overexpression of EZH2 other hsa-mir-196a-2 Lung Neoplasms 19293314 miR-196a-2: Susceptibility of Lung Cancer in Chinese other hsa-mir-122 "Carcinoma, Hepatocellular" 19296470 miR-122: a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma other hsa-mir-199b Medulloblastoma 19308264 miR-199b-5p: MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma other hsa-mir-451a Gastrointestinal Neoplasms 19318487 miR-451: microRNA-451 Regulates Macrophage Migration Inhibitory Factor Proliferation of Gastrointestinal Cancer Cells Production other hsa-mir-1 Heart Failure 19320780 "The implication of several miRNAs in cardiovascular diseases has been well documented such as miRNA-1 in arrhythmia,miRNA-29 in cardiac fibrosis, miRNA-126 in angiogenesis and miRNA-133 in cardiac hypertrophy." other hsa-mir-126 Heart Failure 19320780 "The implication of several miRNAs in cardiovascular diseases has been well documented such as miRNA-1 in arrhythmia,miRNA-29 in cardiac fibrosis, miRNA-126 in angiogenesis and miRNA-133 in cardiac hypertrophy." other hsa-mir-133 Heart Failure 19320780 "The implication of several miRNAs in cardiovascular diseases has been well documented such as miRNA-1 in arrhythmia,miRNA-29 in cardiac fibrosis, miRNA-126 in angiogenesis and miRNA-133 in cardiac hypertrophy." other hsa-mir-29 Heart Failure 19320780 "The implication of several miRNAs in cardiovascular diseases has been well documented such as miRNA-1 in arrhythmia,miRNA-29 in cardiac fibrosis, miRNA-126 in angiogenesis and miRNA-133 in cardiac hypertrophy." other hsa-let-7a-1 Pancreatic Neoplasms 19323605 Let-7a: inhibits in vitro cell proliferation but fails to alter tumor progression other hsa-let-7a-2 Pancreatic Neoplasms 19323605 Let-7a: inhibits in vitro cell proliferation but fails to alter tumor progression other hsa-let-7a-3 Pancreatic Neoplasms 19323605 Let-7a: inhibits in vitro cell proliferation but fails to alter tumor progression other hsa-let-7b Pancreatic Neoplasms 19323605 Let-7b: inhibits in vitro cell proliferation but fails to alter tumor progression other hsa-let-7c Pancreatic Neoplasms 19323605 Let-7c: inhibits in vitro cell proliferation but fails to alter tumor progression other hsa-let-7d Pancreatic Neoplasms 19323605 Let-7d: inhibits in vitro cell proliferation but fails to alter tumor progression other hsa-let-7e Pancreatic Neoplasms 19323605 Let-7e: inhibits in vitro cell proliferation but fails to alter tumor progression other hsa-let-7f-1 Pancreatic Neoplasms 19323605 Let-7f: inhibits in vitro cell proliferation but fails to alter tumor progression other hsa-let-7f-2 Pancreatic Neoplasms 19323605 Let-7f: inhibits in vitro cell proliferation but fails to alter tumor progression other hsa-let-7g Pancreatic Neoplasms 19323605 Let-7g: inhibits in vitro cell proliferation but fails to alter tumor progression other hsa-let-7i Pancreatic Neoplasms 19323605 Let-7i: inhibits in vitro cell proliferation but fails to alter tumor progression other hsa-mir-146a Lupus Vulgaris 19333922 miR-146a: miR-146a contributes to abnormal activation of the type i interferon pathway in human lupus by targeting the key signaling proteins other hsa-mir-221 Hyperglycemia 19351599 miR-221: induced expression other hsa-mir-221 Vascular Disease [unspecific] 19351599 MicroRNA-221 regulates high glucose-induced endothelial dysfunction other hsa-let-7c Prostate Neoplasms 19372056 "We hypothesize that miR-let7c, miR-100, and miR-218 may be involved in the process of metastasization of PC, and their role as controllers of the expression of RAS, c-myc, Laminin 5 ¦Â3, THAP2, SMARCA5, and BAZ2A should be matter of additional studies." other hsa-mir-100 Prostate Neoplasms 19372056 "We hypothesize that miR-let7c, miR-100, and miR-218 may be involved in the process of metastasization of PC, and their role as controllers of the expression of RAS, c-myc, Laminin 5 ¦Â3, THAP2, SMARCA5, and BAZ2A should be matter of additional studies." other hsa-mir-218 Prostate Neoplasms 19372056 "We hypothesize that miR-let7c, miR-100, and miR-218 may be involved in the process of metastasization of PC, and their role as controllers of the expression of RAS, c-myc, Laminin 5 ¦Â3, THAP2, SMARCA5, and BAZ2A should be matter of additional studies." other hsa-mir-34a Neuroblastoma 19373781 "Neuroblastoma (NB) is the most common extracranial solid tumor in children below the age of 5 years. miR-34a, located in chromosome band 1p36, has been recently implicated as a tumor suppressor gene in NB." other hsa-mir-124a Rheumatoid Arthritis 19404929 The results of this study suggest that miR-124a is a key miRNA in the posttranscriptional regulatory mechanisms of RA synoviocytes. other hsa-mir-196a "Carcinoma, Rectal" 19418581 miR-196a exerts a pro-oncogenic influence in colorectal cancer. other hsa-mir-143 Gastrointestinal Neoplasms 19439999 "Taken together, these findings suggest that miR-143 and miR-145 act as anti-oncomirs common to gastrointestinal tumors." other hsa-mir-145 Gastrointestinal Neoplasms 19439999 "Taken together, these findings suggest that miR-143 and miR-145 act as anti-oncomirs common to gastrointestinal tumors." other hsa-mir-34a Neuroblastoma 19461653 "In this review, the evidence for a role of miR-34a and miR-34b/c in the apoptotic response of normal and tumor cells is surveyed." other hsa-mir-224 Pancreatic Neoplasms 19475450 miR-224 and miR-486 are associated with the progression of pancreatic ductal adenocarcinomas other hsa-mir-486 Pancreatic Neoplasms 19475450 miR-224 and miR-486 are associated with the progression of pancreatic ductal adenocarcinomas other hsa-let-7a Ovarian Neoplasms 19477633 Our study also suggests that lin-28B may promote ovarian cancer progression and serve as an unfavourable prognostic marker for the disease. other hsa-mir-129 Bladder Neoplasms 19487295 "We identified several miRNAs with prognostic potential for predicting disease progression (e.g., miR-129, miR-133b, and miR-518c*)." other hsa-mir-133b Bladder Neoplasms 19487295 "We identified several miRNAs with prognostic potential for predicting disease progression (e.g., miR-129, miR-133b, and miR-518c*)." other hsa-mir-26a Glioma 19487573 The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo. other hsa-mir-106a Mesothelioma 19502386 "The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype" other hsa-mir-143 Mesothelioma 19502386 "The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype" other hsa-mir-17 Mesothelioma 19502386 "The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype" other hsa-mir-21 Mesothelioma 19502386 "The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype" other hsa-mir-29a Mesothelioma 19502386 "The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype" other hsa-mir-30c-1 Mesothelioma 19502386 "The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype" other hsa-mir-30c-2 Mesothelioma 19502386 "The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype" other hsa-mir-30e Mesothelioma 19502386 "The expression of miR-17-5p, miR-21, miR-29a, miR-30c, miR-30e-5p, miR-106a, and miR-143 was significantly associated with the histopathological subtype" other hsa-mir-1 Heart Failure 19519553 MiR-1 influences susceptibility to cardiac arrhythmias after myocardial infarction. other hsa-mir-208 Heart Failure 19519553 MiR-208 is involved in the shift toward a fetal gene expression pattern in contractile proteins in heart failure. other hsa-mir-21 Heart Failure 19519553 MiR-29 is involved in fibrotic reaction after myocardial infarction while miR-21 may exert a fundamental role in post-angioplasty restenosis. other hsa-mir-222 Glioblastoma 19520829 "Immunohistochemical and in situ hybridization analyses of 30 primary glioblastoma tissues demonstrated that expression of Dicer, miR-222, or miR-339 was inversely associated with ICAM-1 expression." other hsa-mir-339 Glioblastoma 19520829 "Immunohistochemical and in situ hybridization analyses of 30 primary glioblastoma tissues demonstrated that expression of Dicer, miR-222, or miR-339 was inversely associated with ICAM-1 expression." other hsa-mir-184 Neoplasms [unspecific] 19546886 "laryngeal carcinoma, upregulated; control of the G1-S phase transition;regulate BTG2, a cell cycle gene" other hsa-mir-15a "Carcinoma, Lung, Non-Small-Cell" 19549910 miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer. other hsa-mir-16 "Carcinoma, Lung, Non-Small-Cell" 19549910 miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer. other hsa-mir-29a Breast Neoplasms 19567675 "potentially oncogenic role in breast tumorigenesis; significantly associated with decreased breast cancer risk; mutant precursors of miR-196a-2 into breast cancer cells led to less efficient processing of the miRNA precursor to its mature form as well as diminished capacity to regulate target genes, further showed that cell cycle response to mutagen challenge was significantly enhanced;" other hsa-mir-23a Hepatitis C Virus Infection 19578061 "virus specific, miR-122-sensitive double-helical switch element in the 5' region--a new mechanism of action of micro-RNAs" other hsa-mir-661 "Squamous Cell Carcinoma, Lung" 19584273 miR-146b alone have the strongest prediction accuracy for stratifying prognostic groups; other hsa-let-7 Infection [unspecific] 19592657 "Our data suggest that miR-98 and let-7 confer cholangiocyte expression of CIS in response to microbial challenge, a process that may be relevant to the regulation of TLR-mediated epithelial innate immune response." other hsa-mir-98 Infection [unspecific] 19592657 "Our data suggest that miR-98 and let-7 confer cholangiocyte expression of CIS in response to microbial challenge, a process that may be relevant to the regulation of TLR-mediated epithelial innate immune response." other hsa-mir-141 Neoplasms [unspecific] 19593777 association with cancer progression other hsa-mir-200b Neoplasms [unspecific] 19593777 association with cancer progression other hsa-mir-200c Neoplasms [unspecific] 19593777 association with cancer progression other hsa-mir-205 Neoplasms [unspecific] 19593777 association with cancer progression other hsa-mir-21 Neoplasms [unspecific] 19593777 association with cancer progression other hsa-mir-30a Neoplasms [unspecific] 19593777 association with cancer progression other hsa-mir-30e Neoplasms [unspecific] 19593777 association with cancer progression other hsa-mir-21 Prostate Neoplasms 19597470 acts as tumor suppressor and induces apoptosis of tumor cells through E2F1-mediated suppression of Akt phosphorylation other hsa-mir-330 Prostate Neoplasms 19597470 MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation other hsa-mir-122 Gastrointestinal Neoplasms 19607815 The down-regulation of miR-122a mediated by aberrant APC/beta-catenin signaling is important to the pathogenesis of gastrointestinal cancers. other hsa-mir-125a Myelodysplastic Syndromes 19615744 Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndrome other hsa-mir-221 Myelodysplastic Syndromes 19615744 Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndrome other hsa-mir-222 Myelodysplastic Syndromes 19615744 Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndrome other hsa-mir-599 Multiple Sclerosis 19617918 relevant at the time of relapse other hsa-mir-96 Multiple Sclerosis 19617918 relevant at the time of relapse other hsa-mir-206 Rhabdomyosarcoma 19620785 miR-1 was barely detectable in primary RMS other hsa-mir-34c Rhabdomyosarcoma 19620785 "The muscle-specific microRNA miR-206, blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation" other hsa-mir-188 Cardiovascular Diseases [unspecific] 19669742 These findings suggest that dicer and miRNAs especially miR-188 are involved in Hcy-induced cardiac remodeling other hsa-mir-93 Urinary Bladder Cancer 19671845 control the EMT process and sensitivity to EGFR therapy other hsa-mir-18b Breast Neoplasms 19684618 inhibit Eralpha signaling other hsa-mir-193b Breast Neoplasms 19684618 inhibit Eralpha signaling other hsa-mir-206 Breast Neoplasms 19684618 inhibit Eralpha signaling other hsa-mir-302c Breast Neoplasms 19684618 inhibit Eralpha signaling other hsa-mir-185 Lung Neoplasms 19688090 cell cycle arrest other hsa-mir-18a Lung Neoplasms 19688090 cell cycle arrest other hsa-mir-125a Muscular Dystrophy 19690046 regulation of §Ø©ãmyosin heavy chain gene other hsa-mir-208b Muscular Dystrophy 19690046 regulation of §Ø©ãmyosin heavy chain gene other hsa-mir-107 "Leukemia, Lymphocytic, Chronic, B-Cell" 19692702 "regulation of PLAG1 by miR-181a, miR-181b, miR-107, and miR-424" other hsa-mir-182 Pain 19699278 "association with chronic neuropathic pain, mechanical hypersensitivity" other hsa-mir-183 Pain 19699278 "association with chronic neuropathic pain, mechanical hypersensitivity" other hsa-mir-34a Pain 19699278 "association with chronic neuropathic pain, mechanical hypersensitivity" other hsa-mir-96 Pain 19699278 "association with chronic neuropathic pain, mechanical hypersensitivity" other hsa-mir-155 Gastric Neoplasms 19702585 possible role in the intimate relationship other hsa-mir-15a Myelodysplastic Syndromes 19702585 differentially expressed between low-risk and high-risk other hsa-mir-21 Gastric Neoplasms 19702585 possible role in the intimate relationship other hsa-mir-221 Gastric Neoplasms 19702585 possible role in the intimate relationship other hsa-mir-222 Gastric Neoplasms 19702585 possible role in the intimate relationship other hsa-mir-27a Gastric Neoplasms 19702585 possible role in the intimate relationship other hsa-mir-125a Lung Neoplasms 19702827 "Taken together, our results provide compelling evidence that miR-125a-5p, an epidermal growth factor-signaling-regulated miRNA, may function as a metastatic suppressor." other hsa-mir-200a Meningioma 19703647 Down-regulation Promotes Tumor Growth by reducing E-cadherin and Activating the Wnt/{beta} catenin Signaling Pathway other hsa-mir-200a Meningioma 19703993 "This reveals a previously unrecognized signaling cascade involved in meningioma tumor development and highlights a novel molecular interaction between miR-200a and Wnt signaling, thereby providing insights into novel therapies for meningiomas." other hsa-mir-128-1 Neuroblastoma 19713529 reduce cell motility and invasiveness other hsa-mir-128-2 Neuroblastoma 19713529 reduce cell motility and invasiveness other hsa-mir-34a Pancreatic Neoplasms 19714243 inhibits tumor-initiating cells. other hsa-mir-34b Pancreatic Neoplasms 19714243 inhibits tumor-initiating cells. other hsa-mir-34c Pancreatic Neoplasms 19714243 inhibits tumor-initiating cells. other hsa-mir-146a "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia other hsa-mir-146b "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia other hsa-mir-148a "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia other hsa-mir-151a "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia other hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia other hsa-mir-29b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia other hsa-mir-29c "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia other hsa-mir-34a "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia other hsa-mir-640 "Leukemia, Lymphocytic, Chronic, B-Cell" 19717645 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia other hsa-mir-155 Intracerebral Hemorrhage 19724284 correlate other hsa-mir-298 Intracerebral Hemorrhage 19724284 correlate other hsa-mir-362 Intracerebral Hemorrhage 19724284 correlate other hsa-mir-21 Pancreatic Adenocarcinoma 19730150 "Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma." other hsa-mir-221 Pancreatic Adenocarcinoma 19730150 "Antisense Inhibition of microRNA-21 or -221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma." other hsa-mir-145 Breast Neoplasms 19730444 miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells. other hsa-mir-140 Colon Neoplasms 19734943 high-throughput microRNA (miRNA) expression analysis revealed that the expression of miR-140 was associated with chemosensitivity in osteosarcoma tumor xenografts other hsa-mir-140 Osteosarcoma 19734943 high-throughput microRNA (miRNA) expression analysis revealed that the expression of miR-140 was associated with chemosensitivity in osteosarcoma tumor xenografts other hsa-mir-34a Lung Neoplasms 19736307 relevant to the diagnosis other hsa-mir-500a "Carcinoma, Hepatocellular" 19737067 oncofetal miRNA relevant to the diagnosis other hsa-mir-21 "Adenocarcinoma, Colon" 19737943 predictors of prognosis other hsa-mir-10a Pancreatic Neoplasms 19747919 Inhibition of miR-10a expression (with retinoic acid receptor antagonists) or function (with specific inhibitors) is a promising starting point for antimetastatic therapies. other hsa-mir-126 "Leukemia, Lymphoblastic" 19760605 "ANOVA highlighted a set of six miRNAs-namely miR-425-5p, miR-191, miR-146b, miR-128, miR-629, and miR-126-that can discriminate B-lineage ALL subgroups harboring specific molecular lesions." other hsa-mir-128 "Leukemia, Lymphoblastic" 19760605 "ANOVA highlighted a set of six miRNAs-namely miR-425-5p, miR-191, miR-146b, miR-128, miR-629, and miR-126-that can discriminate B-lineage ALL subgroups harboring specific molecular lesions." other hsa-mir-146b "Leukemia, Lymphoblastic" 19760605 "ANOVA highlighted a set of six miRNAs-namely miR-425-5p, miR-191, miR-146b, miR-128, miR-629, and miR-126-that can discriminate B-lineage ALL subgroups harboring specific molecular lesions." other hsa-mir-191 "Leukemia, Lymphoblastic" 19760605 "ANOVA highlighted a set of six miRNAs-namely miR-425-5p, miR-191, miR-146b, miR-128, miR-629, and miR-126-that can discriminate B-lineage ALL subgroups harboring specific molecular lesions." other hsa-mir-425 "Leukemia, Lymphoblastic" 19760605 "ANOVA highlighted a set of six miRNAs-namely miR-425-5p, miR-191, miR-146b, miR-128, miR-629, and miR-126-that can discriminate B-lineage ALL subgroups harboring specific molecular lesions." other hsa-mir-629 "Leukemia, Lymphoblastic" 19760605 "ANOVA highlighted a set of six miRNAs-namely miR-425-5p, miR-191, miR-146b, miR-128, miR-629, and miR-126-that can discriminate B-lineage ALL subgroups harboring specific molecular lesions." other hsa-mir-17 Prostate Neoplasms 19771525 "MicroRNA-17-3p is a prostate tumor suppressor in vitro and in vivo, and is decreased in high grade prostate tumors analyzed by laser capture microdissection." other hsa-mir-210 Pancreatic Neoplasms 19782034 "When human head and neck or pancreatic tumor cells ectopically expressing mir-210 were implanted into immunodeficient mice, mir-210 repressed initiation of tumor growth." other hsa-let-7a Laryngeal Neoplasms 19787239 "Thus, we propose that let-7a may be a tumor suppressor in laryngeal cancer by inhibiting cell growth, inducing cell apoptosis and downregulating the oncogenes expression." other hsa-mir-375 Diabetes Mellitus 19800254 "Recent studies, for example, implicate miR-375 in pancreatic islet cell viability and function, and removal or overexpression of miR-375 profoundly affects glucose metabolism. " other hsa-mir-421 Gastrointestinal Neoplasms 19802518 miR-421 may involve in the early stage of stomach carcinogenesis and could be used as an efficient diagnostic biomarker. other hsa-mir-106b Alopecia 19821055 "mir-106b:four microRNAs (miR-221, miR-125b, miR-106b and miR-410) that could participate in pathogenesis of MPB" other hsa-mir-125b-1 Alopecia 19821055 "miR-125b:four microRNAs (miR-221, miR-125b, miR-106b and miR-410) that could participate in pathogenesis of MPB" other hsa-mir-125b-2 Alopecia 19821055 "miR-125b:four microRNAs (miR-221, miR-125b, miR-106b and miR-410) that could participate in pathogenesis of MPB" other hsa-mir-221 Alopecia 19821055 "miR-221:four microRNAs (miR-221, miR-125b, miR-106b and miR-410) that could participate in pathogenesis of MPB" other hsa-mir-410 Alopecia 19821055 "miR-410:four microRNAs (miR-221, miR-125b, miR-106b and miR-410) that could participate in pathogenesis of MPB" other hsa-mir-141 Colorectal Carcinoma 19830559 miR-141:miR-141 regulates SIP1 to inhibit migration and invasion of CRC cells other hsa-mir-326 Multiple Sclerosis 19838199 miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis other hsa-mir-200a Breast Neoplasms 19839049 miR-200a:microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells other hsa-mir-200b Breast Neoplasms 19839049 miR-200b:microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells other hsa-mir-200c Breast Neoplasms 19839049 miR-200c:microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells other hsa-mir-143 Colorectal Carcinoma 19843160 "Collectively, the data obtained in the present study suggest anti-proliferative, chemosensitizer and putative pro-apoptotic roles for miR-143 in colon cancer." other hsa-mir-143 Colorectal Carcinoma 19843336 In vitro functional studies indicated that miR-143 and miR-145 appear to function in opposing manners to either inhibit or augment cell proliferation in a metastatic CRC model. other hsa-mir-145 Colorectal Carcinoma 19843336 In vitro functional studies indicated that miR-143 and miR-145 appear to function in opposing manners to either inhibit or augment cell proliferation in a metastatic CRC model. other hsa-mir-130a Adrenal Cortex Neoplasms 19849700 miR-130a:miR-130a and miR-382 as putative diagnostic MMAD markers other hsa-mir-382 Adrenal Cortex Neoplasms 19849700 miR-382:miR-130a and miR-382 as putative diagnostic MMAD markers other hsa-mir-144 Schizophrenia 19849891 "The most promising miRNAs so far identified include miR-181, miR-346 and miR-195 in schizophrenia and miR-34a and miR-144 in bipolar disorder." other hsa-mir-181 Schizophrenia 19849891 "The most promising miRNAs so far identified include miR-181, miR-346 and miR-195 in schizophrenia and miR-34a and miR-144 in bipolar disorder." other hsa-mir-195 Schizophrenia 19849891 "The most promising miRNAs so far identified include miR-181, miR-346 and miR-195 in schizophrenia and miR-34a and miR-144 in bipolar disorder." other hsa-mir-346 Schizophrenia 19849891 "The most promising miRNAs so far identified include miR-181, miR-346 and miR-195 in schizophrenia and miR-34a and miR-144 in bipolar disorder." other hsa-mir-34a Schizophrenia 19849891 "The most promising miRNAs so far identified include miR-181, miR-346 and miR-195 in schizophrenia and miR-34a and miR-144 in bipolar disorder." other hsa-mir-500 "Carcinoma, Hepatocellular" 19863192 "Our findings reveal that diverse changes of miRNAs occur during liver development and, one of these, miR-500 is an oncofetal miRNA relevant to the diagnosis of human HCC." other hsa-mir-15a "Leukemia, Myeloid, Acute" 19883312 miR-15a in BM ( p = 0.034) and miR-16 in PB ( p = 0.005) were differentially expressed between low-risk and high-risk groups other hsa-mir-222 "Leukemia, Myeloid, Acute" 19883312 miR-222 ( p = 0.0023) and miR-181a ( p = 0.014) expression was higher in AML than in MDS other hsa-mir-326 Breast Neoplasms 19883630 Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1 other hsa-mir-17 Neoplasms [unspecific] 19887902 miR-17-5p has initially been linked to tumorigenesis other hsa-mir-18a Neoplasms [unspecific] 19887902 has initially been linked to tumorigenesis other hsa-mir-19a Neoplasms [unspecific] 19887902 has initially been linked to tumorigenesis other hsa-mir-20a Neoplasms [unspecific] 19887902 has initially been linked to tumorigenesis other hsa-mir-138-1 Leukemia 19896708 miR-138:miR-138 might reverse multidrug resistance of leukemia cells other hsa-mir-138-2 Leukemia 19896708 miR-138:miR-138 might reverse multidrug resistance of leukemia cells other hsa-mir-145 Myelodysplastic Syndromes 19898489 "5q- syndrome deleted,Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype" other hsa-mir-146a Myelodysplastic Syndromes 19898489 "5q- syndrome deleted,Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype" other hsa-mir-17 Severe Acute Respiratory Syndrome Virus Infection 19915717 "Upregulated BASC miRNAs-17*, -574-5p, and -214 are co-opted by SARS-CoV to suppress its own replication and evade immune elimination" other hsa-mir-214 Severe Acute Respiratory Syndrome Virus Infection 19915717 "Upregulated BASC miRNAs-17*, -574-5p, and -214 are co-opted by SARS-CoV to suppress its own replication and evade immune elimination" other hsa-mir-574 Severe Acute Respiratory Syndrome Virus Infection 19915717 "Upregulated BASC miRNAs-17*, -574-5p, and -214 are co-opted by SARS-CoV to suppress its own replication and evade immune elimination" other hsa-mir-126 Vascular Disease [unspecific] 19917099 "miR-126, miR-24 and miR-23a are selectively expressed in microvascular endothelial cells in vivo" other hsa-mir-145 Vascular Disease [unspecific] 19917099 elevated levels of miR-145 reduced migration of microvascular cells in response to growth factor gradients in vitro other hsa-mir-23a Vascular Disease [unspecific] 19917099 "miR-126, miR-24 and miR-23a are selectively expressed in microvascular endothelial cells in vivo" other hsa-mir-25 Endomyocardial Fibrosis 19919989 both miR-25 and miR-29a were sufficient to decrease collagen gene expression other hsa-mir-29a Endomyocardial Fibrosis 19919989 both miR-25 and miR-29a were sufficient to decrease collagen gene expression other hsa-mir-27a Breast Neoplasms 19921425 "We hypothesize that the G-variant of rs895819 might impair the maturation of the oncogenic miR-27a and thus, is associated with familial breast cancer risk." other hsa-mir-34a Lung Neoplasms 19921694 miR-34a:MicroRNA-34a is an important component of PRIMA-1-induced apoptotic network in human lung cancer cells other hsa-mir-17 Lymphoma 19933089 "miR-17-5p can induce tumorigenesis, such as lymphoma and vascularized tumor as an oncogene" other hsa-mir-18a Lymphoma 19933089 "it can induce tumorigenesis, such as lymphoma and vascularized tumor as an oncogene" other hsa-mir-19a Lymphoma 19933089 "it can induce tumorigenesis, such as lymphoma and vascularized tumor as an oncogene" other hsa-mir-20a Lymphoma 19933089 "it can induce tumorigenesis, such as lymphoma and vascularized tumor as an oncogene" other hsa-mir-21 Glioma 19934272 the results of our study show that the downregulation of miR-21 contributes to the antitumor effects of IFN-beta and that miR-21 expression is negatively regulated by STAT3 activation. These results highlight the importance of understanding the transcriptional regulation of the miRNAs involved in oncogenesis. other hsa-mir-140 Osteoarthritis 19948051 "We investigated whether two highly predicted microRNAs (miRNAs), miR-140 and miR-27a, regulate these two genes in human OA chondrocytes." other hsa-mir-27a Osteoarthritis 19948051 "We investigated whether two highly predicted microRNAs (miRNAs), miR-140 and miR-27a, regulate these two genes in human OA chondrocytes." other hsa-let-7g Gastric Neoplasms 19948396 "different miRNAs have been found to predict sensitivity to anticancer treatment: miR-30c, miR-130a and miR-335 are downregulated in various chemoresistant cell lines, hsa-Let-7g and hsa-miR-181b are strongly associated with response to 5-fluorouracil-based antimetabolite S-1" other hsa-mir-181b Gastric Neoplasms 19948396 "different miRNAs have been found to predict sensitivity to anticancer treatment: miR-30c, miR-130a and miR-335 are downregulated in various chemoresistant cell lines, hsa-Let-7g and hsa-miR-181b are strongly associated with response to 5-fluorouracil-based antimetabolite S-1" other hsa-mir-126 Gastrointestinal Neoplasms 19951901 "We have identified a seven-miRNA signature (miR-10b, miR-21, miR-223, miR-338, let-7a, miR-30a-5p, miR-126) for overall survival (p=0.0009) and relapse-free survival (p=0.0005) of gastric cancer patients. " other hsa-mir-29a Irritable Bowel Syndrome 19951903 miR-29a:MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome other hsa-mir-27a "Squamous Cell Carcinoma, Esophageal" 19960259 miR-27a:Down-regulation of miR-27a might reverse multidrug resistance of esophageal squamous cell carcinoma other hsa-mir-146a Immune System Disease [unspecific] 19965651 "Our results demonstrate that several signaling pathways, other than inflammation, are influenced by miR-146a. In particular, we provide experimental evidence that miR-146a modulates activation-induced cell death (AICD), acting as an antiapoptotic factor, and that Fas-associated death domain (FADD) is a target of miR-146a." other hsa-mir-122 Hepatitis C Virus Infection 19965718 a locked nucleic acid (LNA)-modified oligonucleotide (SPC3649) complementary to miR-122 leads to long-lasting suppression of HCV viremia other hsa-mir-145 Breast Neoplasms 19996288 "Taken together, these results suggest that as a tumor suppressor, miR-145 inhibits not only tumor growth but also cell invasion and metastasis." other hsa-mir-145 Prostate Neoplasms 19996289 miR-145 and miR-331-3p are predicted to target 3 of the 20 hub genes other hsa-mir-331 Prostate Neoplasms 19996289 miR-145 and miR-331-3p are predicted to target 3 of the 20 hub genes other hsa-mir-126 Atherosclerosis 19996457 Administration of apoptotic bodies or miR-126 limited atherosclerosis other hsa-mir-21 Cystic Fibrosis 19997496 "mir-125b-1, mir-21, mir-30b, and mir-23b-27b-24-1 cluster genes were transactivated through promoter binding of the NF-kappaB p65 subunit following C. parvum infection" other hsa-mir-23b Cystic Fibrosis 19997496 "mir-125b-1, mir-21, mir-30b, and mir-23b-27b-24-1 cluster genes were transactivated through promoter binding of the NF-kappaB p65 subunit following C. parvum infection" other hsa-mir-27b Cystic Fibrosis 19997496 "mir-125b-1, mir-21, mir-30b, and mir-23b-27b-24-1 cluster genes were transactivated through promoter binding of the NF-kappaB p65 subunit following C. parvum infection" other hsa-mir-30b Cystic Fibrosis 19997496 "mir-125b-1, mir-21, mir-30b, and mir-23b-27b-24-1 cluster genes were transactivated through promoter binding of the NF-kappaB p65 subunit following C. parvum infection" other hsa-mir-31 Intestinal Schistosomiasis 19997615 "some nucleotides at many positions of Schistosoma miRNAs, such as miR-8, let-7, miR-10, miR-31, miR-92, miR-124, and miR-125, are indeed significantly distinct from other bilaterian orthologs" other hsa-let-7a-1 Retinoblastoma 20004941 "Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas." other hsa-let-7a-2 Retinoblastoma 20004941 "Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas." other hsa-let-7a-3 Retinoblastoma 20004941 "Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas." other hsa-let-7b Retinoblastoma 20004941 "Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas." other hsa-let-7c Retinoblastoma 20004941 "Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas." other hsa-let-7d Retinoblastoma 20004941 "Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas." other hsa-let-7e Retinoblastoma 20004941 "Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas." other hsa-let-7f-1 Retinoblastoma 20004941 "Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas." other hsa-let-7f-2 Retinoblastoma 20004941 "Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas." other hsa-let-7g Retinoblastoma 20004941 "Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas." other hsa-let-7i Retinoblastoma 20004941 "Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation,invasion, and proliferation associated with let-7 down-regulation in retinoblastomas." other hsa-mir-132 Inflammation 20005135 MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase other hsa-mir-1181 Hepatitis C Virus Infection 20006370 "miR-24, miR-149, miR-638 and miR-1181 were identified to be involved in HCV entry, replication and propagation" other hsa-mir-149 Hepatitis C Virus Infection 20006370 "miR-24, miR-149, miR-638 and miR-1181 were identified to be involved in HCV entry, replication and propagation" other hsa-mir-24-1 Hepatitis C Virus Infection 20006370 "miR-24, miR-149, miR-638 and miR-1181 were identified to be involved in HCV entry, replication and propagation" other hsa-mir-24-2 Hepatitis C Virus Infection 20006370 "miR-24, miR-149, miR-638 and miR-1181 were identified to be involved in HCV entry, replication and propagation" other hsa-mir-638 Hepatitis C Virus Infection 20006370 "miR-24, miR-149, miR-638 and miR-1181 were identified to be involved in HCV entry, replication and propagation" other hsa-mir-206 Amyotrophic Lateral Sclerosis 20007902 MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice other hsa-mir-19a Neoplasms [unspecific] 20008935 miR-19 is a key oncogenic component of mir-17-92 other hsa-mir-19b-1 Neoplasms [unspecific] 20008935 miR-19 is a key oncogenic component of mir-17-92 other hsa-mir-19b-2 Neoplasms [unspecific] 20008935 miR-19 is a key oncogenic component of mir-17-92 other hsa-mir-146a Chlamydial Infection 20011700 microRNA-146a is a negative regulator of Tolllike receptor (TLR) signaling other hsa-mir-133a-1 "Cardiomyopathy, Hypertrophic" 20013939 miR133a regulates cardiomyocyte hypertrophy in diabetes other hsa-mir-133a-2 "Cardiomyopathy, Hypertrophic" 20013939 miR133a regulates cardiomyocyte hypertrophy in diabetes other hsa-let-7c "Carcinoma, Hepatocellular" 20018759 "A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC" other hsa-mir-21 "Carcinoma, Hepatocellular" 20018759 "A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC" other hsa-mir-222 "Carcinoma, Hepatocellular" 20018759 "A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC" other hsa-mir-34a "Carcinoma, Hepatocellular" 20018759 "A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC" other hsa-mir-93 "Carcinoma, Hepatocellular" 20018759 "A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC" other hsa-mir-96 "Carcinoma, Hepatocellular" 20018759 "A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93, miR-96, and let-7c) was linked to disease progression from normal liver through cirrhosis to full-blown HCC" other hsa-let-7a Retinoblastoma 20019750 "miRNA profiling of these tumors identified members of the let-7 and miR-34(34b,34c) families as candidate tumor suppressors in retinoblastoma." other hsa-let-7b Retinoblastoma 20019750 "miRNA profiling of these tumors identified members of the let-7 and miR-34(34b,34c) families as candidate tumor suppressors in retinoblastoma." other hsa-let-7c Retinoblastoma 20019750 "miRNA profiling of these tumors identified members of the let-7 and miR-34(34b,34c) families as candidate tumor suppressors in retinoblastoma." other hsa-let-7d Retinoblastoma 20019750 "miRNA profiling of these tumors identified members of the let-7 and miR-34(34b,34c) families as candidate tumor suppressors in retinoblastoma." other hsa-let-7e Retinoblastoma 20019750 "miRNA profiling of these tumors identified members of the let-7 and miR-34(34b,34c) families as candidate tumor suppressors in retinoblastoma." other hsa-let-7f Retinoblastoma 20019750 "miRNA profiling of these tumors identified members of the let-7 and miR-34(34b,34c) families as candidate tumor suppressors in retinoblastoma." other hsa-let-7g Retinoblastoma 20019750 "miRNA profiling of these tumors identified members of the let-7 and miR-34(34b,34c) families as candidate tumor suppressors in retinoblastoma." other hsa-let-7i Retinoblastoma 20019750 "miRNA profiling of these tumors identified members of the let-7 and miR-34(34b,34c) families as candidate tumor suppressors in retinoblastoma." other hsa-mir-202 Retinoblastoma 20019750 "miRNA profiling of these tumors identified members of the let-7 and miR-34(34b,34c) families as candidate tumor suppressors in retinoblastoma." other hsa-mir-34b Retinoblastoma 20019750 "miRNA profiling of these tumors identified members of the let-7 and miR-34(34b,34c) families as candidate tumor suppressors in retinoblastoma." other hsa-mir-34c Retinoblastoma 20019750 "miRNA profiling of these tumors identified members of the let-7 and miR-34(34b,34c) families as candidate tumor suppressors in retinoblastoma." other hsa-mir-98 Retinoblastoma 20019750 "miRNA profiling of these tumors identified members of the let-7 and miR-34(34b,34c) families as candidate tumor suppressors in retinoblastoma." other hsa-mir-20a "Carcinoma, Renal Cell" 20022054 Transfection of miR-20a inhibitor significantly decreased cell proliferation in a dose dependent manner. other hsa-mir-100 Gastric Neoplasms 20022810 "progression-related signature, miR-125b, miR-199a, and miR-100 were the most important microRNAs involved" other hsa-mir-146a Kaposi Sarcoma 20023696 Our results show that K13-induced NF-kappaB activity suppresses CXCR4 through upregulation of miR-146a. other hsa-mir-200a Ovarian Neoplasms 20035894 miR-200a:involved in epithelial-to-mesenchymal transition (EMT) other hsa-mir-200b Ovarian Neoplasms 20035894 miR-200b:involved in epithelial-to-mesenchymal transition (EMT) other hsa-mir-200c Ovarian Neoplasms 20035894 miR-200c:involved in epithelial-to-mesenchymal transition (EMT) other hsa-mir-1-1 Chordoma 20041488 miR-1:miRNA-1 may have a functional effect on chordoma tumor pathogenesis other hsa-mir-1-2 Chordoma 20041488 miR-1:miRNA-1 may have a functional effect on chordoma tumor pathogenesis other hsa-mir-128a Breast Neoplasms 20054641 These data suggest that the hormone-responsive miR-128a can modulate TGF¦Â signaling and survival of the letrozole-resistant cell lines. other hsa-mir-132 Inflammation 20064444 Boosting the brain's ability to block inflammation via microRNA-132. other hsa-mir-10b Esophageal Neoplasms 20075075 MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines. other hsa-mir-21 Breast Neoplasms 20082533 Downregulation of miR-21 enhances chemotherapeutic effect of taxol in breast carcinoma cells other hsa-mir-130a Ovarian Neoplasms 20083225 "we discuss several other microRNAs that have been associated with chemotherapy resistance, such as miR-214, miR-130a, miR-27a and miR-451. In the final section, we speculate on the possibilities of microRNA-based therapies and the use of microRNAs as diagnostic tools." other hsa-mir-214 Ovarian Neoplasms 20083225 "we discuss several other microRNAs that have been associated with chemotherapy resistance, such as miR-214, miR-130a, miR-27a and miR-451. In the final section, we speculate on the possibilities of microRNA-based therapies and the use of microRNAs as diagnostic tools." other hsa-mir-27a Ovarian Neoplasms 20083225 "we discuss several other microRNAs that have been associated with chemotherapy resistance, such as miR-214, miR-130a, miR-27a and miR-451. In the final section, we speculate on the possibilities of microRNA-based therapies and the use of microRNAs as diagnostic tools." other hsa-mir-451 Ovarian Neoplasms 20083225 "we discuss several other microRNAs that have been associated with chemotherapy resistance, such as miR-214, miR-130a, miR-27a and miR-451. In the final section, we speculate on the possibilities of microRNA-based therapies and the use of microRNAs as diagnostic tools." other hsa-mir-23a Neoplasms [unspecific] 20086171 "In addition to its known function in regulating the cell cycle and glucose metabolism, recent studies document a role for Myc in stimulating glutamine catabolism, in part through the repression of miRNAs miR-23a and miR-23b." other hsa-mir-23b Neoplasms [unspecific] 20086171 "In addition to its known function in regulating the cell cycle and glucose metabolism, recent studies document a role for Myc in stimulating glutamine catabolism, in part through the repression of miRNAs miR-23a and miR-23b." other hsa-mir-146a Diabetes Mellitus 20086228 "Our data identify miR-21, miR-34a, and miR-146a as novel players in beta-cell failure elicited in vitro and in vivo by proinflammatory cytokines,notably during the development of peri-insulitis that precedes overt diabetes in NOD mice." other hsa-mir-21 Diabetes Mellitus 20086228 "Our data identify miR-21, miR-34a, and miR-146a as novel players in beta-cell failure elicited in vitro and in vivo by proinflammatory cytokines,notably during the development of peri-insulitis that precedes overt diabetes in NOD mice." other hsa-mir-34a Diabetes Mellitus 20086228 "Our data identify miR-21, miR-34a, and miR-146a as novel players in beta-cell failure elicited in vitro and in vivo by proinflammatory cytokines,notably during the development of peri-insulitis that precedes overt diabetes in NOD mice." other hsa-mir-29a "Lymphoma, B-Cell" 20086245 "our results in primary MCL cells indicate that down-regulation of miR-29 could cooperate with cyclin D1 in MCL pathogenesis. Thus, our findings provide not only miRNA expression signature but also a novel prognostic marker and pathogenetic factor for this malignancy." other hsa-mir-106b Toxoplasma gondii Infection 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases other hsa-mir-17 Toxoplasma gondii Infection 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases other hsa-mir-18a Toxoplasma gondii Infection 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases other hsa-mir-19a Toxoplasma gondii Infection 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases other hsa-mir-19b-1 Toxoplasma gondii Infection 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases other hsa-mir-19b-2 Toxoplasma gondii Infection 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases other hsa-mir-20a Toxoplasma gondii Infection 20090903 play crucial roles in mammalian cell regulation and have been implicated in numerous hyperproliferative diseases other hsa-mir-21 Prostate Neoplasms 20092645 oncogenic properties of miR-21 could be cell and tissue dependent other hsa-mir-143 Colorectal Carcinoma 20094072 anti-oncomirs other hsa-let-7a-1 Lung Neoplasms 20097187 inhibition of proliferation in non-small cell lung cancer other hsa-let-7a-2 Lung Neoplasms 20097187 inhibition of proliferation in non-small cell lung cancer other hsa-let-7a-3 Lung Neoplasms 20097187 inhibition of proliferation in non-small cell lung cancer other hsa-mir-126 Lung Neoplasms 20097187 inhibition of proliferation in non-small cell lung cancer other hsa-mir-145 Lung Neoplasms 20097187 inhibition of proliferation in non-small cell lung cancer other hsa-mir-146a "Leukemia, Myeloid, Acute" 20110180 "Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients," other hsa-mir-146a "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 20110180 "Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients," other hsa-mir-181a-2 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 20110180 "Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients," other hsa-mir-181c "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 20110180 "Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients," other hsa-mir-196b "Leukemia, Myeloid, Acute" 20110180 "Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients," other hsa-mir-221 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 20110180 "Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients," other hsa-mir-25 "Leukemia, Myeloid, Acute" 20110180 "Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients," other hsa-mir-26a-1 "Leukemia, Myeloid, Acute" 20110180 "Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients," other hsa-mir-26a-2 "Leukemia, Myeloid, Acute" 20110180 "Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients," other hsa-mir-29b-1 "Leukemia, Myeloid, Acute" 20110180 "Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients," other hsa-mir-29b-2 "Leukemia, Myeloid, Acute" 20110180 "Of them, three (i.e., miR-146a, miR-181a/c, and miR-221), five (i.e., miR-25, miR-26a, miR-29b, miR-146a, and miR-196b), and three (i.e.,miR-26a, miR-29b, and miR-146a) miRNAs are significantly associated with overall survival (P<0.05) of the 32 ALL, 53 AML, and 40 non-M3 AML patients," other hsa-mir-221 Inflammation 20110463 "Functional inhibition of miR-221 with anti-miR-221 induced ICAM-1 protein expression. Moreover, IFN-gamma stimulation decreased miR-221 expression in cholangiocytes in a signal transducer and activator of transcription 1-dependent manner." other hsa-mir-146a Pancreatic Neoplasms 20124483 miR-146a suppresses invasion of pancreatic cancer cells. other hsa-mir-200a Urinary Bladder Cancer 20124485 play important regulatory roles in cervical cancer control other hsa-mir-196a-1 "Carcinoma, Hepatocellular" 20127796 miR-196:MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression other hsa-mir-196a-2 "Carcinoma, Hepatocellular" 20127796 miR-196:MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression other hsa-mir-27b Osteoarthritis 20131257 miR-27b:MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes other hsa-mir-155 Lymphoma 20133617 "Together, our data helped explain miR-155 function, highlighted a hitherto unappreciated role of SMAD5 in lymphoma biology, and defined a unique mechanism used by cancer cells to escape TGF-beta's growth-inhibitory effects." other hsa-mir-125b-1 Neoplasms [unspecific] 20144731 "miR-125b:in macrophages, miR-125b, miR-146, and miR-155 act as Pathogen Associated Molecular Pattern Molecule-associated microRNAs" other hsa-mir-125b-2 Neoplasms [unspecific] 20144731 "miR-125b:in macrophages, miR-125b, miR-146, and miR-155 act as Pathogen Associated Molecular Pattern Molecule-associated microRNAs" other hsa-mir-146a Neoplasms [unspecific] 20144731 "miR-146:in macrophages, miR-125b, miR-146, and miR-155 act as Pathogen Associated Molecular Pattern Molecule-associated microRNAs" other hsa-mir-155 Neoplasms [unspecific] 20144731 "miR-155:in macrophages, miR-125b, miR-146, and miR-155 act as Pathogen Associated Molecular Pattern Molecule-associated microRNAs" other hsa-mir-17 Neoplasms [unspecific] 20144731 "miR-17:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a" other hsa-mir-181a-1 Neoplasms [unspecific] 20144731 "miR-181a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a" other hsa-mir-181a-2 Neoplasms [unspecific] 20144731 "miR-181a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a" other hsa-mir-18a Neoplasms [unspecific] 20144731 "miR-18a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a" other hsa-mir-19a Neoplasms [unspecific] 20144731 "miR-19a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a" other hsa-mir-19b-1 Neoplasms [unspecific] 20144731 "miR-19b:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a" other hsa-mir-19b-2 Neoplasms [unspecific] 20144731 "miR-19b:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a" other hsa-mir-20a Neoplasms [unspecific] 20144731 "miR-20a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a" other hsa-mir-214 Neoplasms [unspecific] 20144731 miR-214:miR-34C and miR-214 as Damage Associated Molecular Pattern Molecules-associated miRs other hsa-mir-34c Neoplasms [unspecific] 20144731 miR-34c:miR-34C and miR-214 as Damage Associated Molecular Pattern Molecules-associated miRs other hsa-mir-92a-1 Neoplasms [unspecific] 20144731 "miR-92a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a" other hsa-mir-92a-2 Neoplasms [unspecific] 20144731 "miR-92a:Targets identified already in T cells include microRNAs, miR-17-92 family, miR-155, and miR-181a" other hsa-mir-31 Neoplasms [unspecific] 20145132 miR-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma other hsa-mir-125b-1 Melanoma 20153427 "miR-125b:miRNA125b may be involved in the regulation of VDR expression and in the resistance against 1,25(OH)(2)D(3) in melanoma cells" other hsa-mir-125b-2 Melanoma 20153427 "miR-125b:miRNA125b may be involved in the regulation of VDR expression and in the resistance against 1,25(OH)(2)D(3) in melanoma cells" other hsa-mir-21 Prostate Neoplasms 20160498 "The transcriptional regulation of miR-21, its multiple transcripts, and their implication in prostate cancer" other hsa-mir-1 Myocardial Infarction 20163779 We conclude that miR-1 and miR-133 seem to be important regulators of heart adaptation after ischaemic stress. other hsa-mir-133b Myocardial Infarction 20163779 We conclude that miR-1 and miR-133 seem to be important regulators of heart adaptation after ischaemic stress. other hsa-mir-27b Inflammation 20164187 We provide evidence that LPS-induced miR-27b contributes to destabilization of PPARgamma1 mRNA. Understanding molecular mechanisms decreasing PPARgamma might help to better appreciate inflammatory diseases. other hsa-mir-9-1 "Cardiomyopathy, Hypertrophic" 20177053 miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy other hsa-mir-9-2 "Cardiomyopathy, Hypertrophic" 20177053 miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy other hsa-mir-9-3 "Cardiomyopathy, Hypertrophic" 20177053 miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy other hsa-let-7f "Carcinoma, Renal Cell" 20180642 Transfection of miR-224 into HEK-293 cells resulted in decreased KLK1 protein levels. A luciferase assay demonstrated that hsa-let-7f can target KLK10 in the RCC cell line ACHN. other hsa-mir-224 "Carcinoma, Renal Cell" 20180642 Transfection of miR-224 into HEK-293 cells resulted in decreased KLK1 protein levels. A luciferase assay demonstrated that hsa-let-7f can target KLK10 in the RCC cell line ACHN. other hsa-mir-34a Brain Neoplasms 20190569 microRNA-34a is tumor suppressive in brain tumors and glioma stem cells other hsa-mir-34a Glioma 20190569 microRNA-34a is tumor suppressive in brain tumors and glioma stem cells other hsa-mir-125b-2 Acute Megakaryoblastic Leukemia 20194440 we propose miR-125b-2 as a positive regulator of megakaryopoiesis and an oncomiR involved in the pathogenesis of trisomy 21-associated megakaryoblastic leukemia. other hsa-mir-1-1 "Carcinoma, Lung, Non-Small-Cell" 20194856 significantly associated with overal survival other hsa-mir-1-2 "Carcinoma, Lung, Non-Small-Cell" 20194856 significantly associated with overal survival other hsa-mir-30d "Carcinoma, Lung, Non-Small-Cell" 20194856 significantly associated with overal survival other hsa-mir-30d Lung Neoplasms 20194856 "levels of four miRNAs (ie, miR-486, miR-30d, miR-1 and miR-499) were significantly associated with overall survival" other hsa-mir-486 "Carcinoma, Lung, Non-Small-Cell" 20194856 significantly associated with overal survival other hsa-mir-486 Lung Neoplasms 20194856 "levels of four miRNAs (ie, miR-486, miR-30d, miR-1 and miR-499) were significantly associated with overall survival" other hsa-mir-499a "Carcinoma, Lung, Non-Small-Cell" 20194856 significantly associated with overal survival other hsa-mir-499a Lung Neoplasms 20194856 "levels of four miRNAs (ie, miR-486, miR-30d, miR-1 and miR-499) were significantly associated with overall survival" other hsa-mir-146a Acute Coronary Syndrome 20195282 miR-146a in PBMCs modulates Th1 function in patients with acute coronary syndrome other hsa-mir-146a Atherosclerosis 20195282 "this study also provided evidence that miR-146a treatment in vitro could induce the protein expression of TNF-alpha, MCP-1, NF-kappaB p65, which are key pro-inflammatory cytokines and critical transcription factor in AS" other hsa-mir-17 Multiple Sclerosis 20201009 "Specifically, miR-17-5p, which is involved in autoimmunity, is upregulated in CD4(+) cells from MS patients" other hsa-mir-216 "Carcinoma, Hepatocellular" 20206398 We also found an inverse correlation between IGF activation and miR-100/miR-216 levels (FDR<0.05). other hsa-mir-146a Inflammation 20214679 miR-146a in reactive astrocytes supports the possible involvement of miRNAs in the modulation of the astroglial inflammatory response other hsa-mir-21 Neoplasms [unspecific] 20219416 "miR-21 serves as a chemosensitive miRNA, while miR-214 and -23a serve as chemoresistant miRNAs in the tongue squamous cell carcinoma lines" other hsa-mir-214 Neoplasms [unspecific] 20219416 "miR-21 serves as a chemosensitive miRNA, while miR-214 and -23a serve as chemoresistant miRNAs in the tongue squamous cell carcinoma lines" other hsa-mir-23a Neoplasms [unspecific] 20219416 "miR-21 serves as a chemosensitive miRNA, while miR-214 and -23a serve as chemoresistant miRNAs in the tongue squamous cell carcinoma lines" other hsa-mir-451a Glioma 20227367 MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells other hsa-mir-17 Neoplasms [unspecific] 20227518 "mir-17-92, a cluster of miRNAs in the midst of the cancer network" other hsa-mir-18a Neoplasms [unspecific] 20227518 "mir-17-92, a cluster of miRNAs in the midst of the cancer network" other hsa-mir-19a Neoplasms [unspecific] 20227518 "mir-17-92, a cluster of miRNAs in the midst of the cancer network" other hsa-mir-19b-1 Neoplasms [unspecific] 20227518 "mir-17-92, a cluster of miRNAs in the midst of the cancer network" other hsa-mir-19b-2 Neoplasms [unspecific] 20227518 "mir-17-92, a cluster of miRNAs in the midst of the cancer network" other hsa-mir-20a Neoplasms [unspecific] 20227518 "mir-17-92, a cluster of miRNAs in the midst of the cancer network" other hsa-mir-92a-1 Neoplasms [unspecific] 20227518 "miR-92a:mir-17-92, a cluster of miRNAs in the midst of the cancer network" other hsa-mir-92a-2 Neoplasms [unspecific] 20227518 "miR-92a:mir-17-92, a cluster of miRNAs in the midst of the cancer network" other hsa-mir-134 Coronary Artery Disease 20230787 "a cluster of three microRNAs including miR-134, miR-198, and miR-370, suggesting that the microRNA signatures can be used to identify patients at risk for acute coronary syndromes" other hsa-mir-198 Coronary Artery Disease 20230787 "a cluster of three microRNAs including miR-134, miR-198, and miR-370, suggesting that the microRNA signatures can be used to identify patients at risk for acute coronary syndromes" other hsa-mir-370 Coronary Artery Disease 20230787 "a cluster of three microRNAs including miR-134, miR-198, and miR-370, suggesting that the microRNA signatures can be used to identify patients at risk for acute coronary syndromes" other hsa-mir-210 Inflammation 20237418 miR-210 appears to function as a master microRNA relevant for the control of diverse functions in the hypoxic state other hsa-mir-210 Ischemia 20237418 miR-210 appears to function as a master microRNA relevant for the control of diverse functions in the hypoxic state other hsa-mir-210 Neoplasms [unspecific] 20237418 miR-210 appears to function as a master microRNA relevant for the control of diverse functions in the hypoxic state other hsa-mir-21 Multiple Myeloma 20302778 miR-21 acts as an oncogene and miR-30b a tumor suppressor gene in MM other hsa-mir-30b Multiple Myeloma 20302778 miR-21 acts as an oncogene and miR-30b a tumor suppressor gene in MM other hsa-mir-151a Glioblastoma 20305651 "significantly increases HCC cell migration and invasion in vitro and in vivo, mainly through miR-151-5p, but not through miR-151-3p" other hsa-mir-17 Glioblastoma 20305691 De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures other hsa-mir-18a Glioblastoma 20305691 De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures other hsa-mir-19a Glioblastoma 20305691 De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures other hsa-mir-19b-1 Glioblastoma 20305691 De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures other hsa-mir-19b-2 Glioblastoma 20305691 De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures other hsa-mir-20a Glioblastoma 20305691 De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures other hsa-mir-126 "Adenocarcinoma, Esophageal" 20309880 "we found that miR-126 expression was associated with tumor cell de-differentiation and lymph node metastasis," other hsa-mir-16-2 "Adenocarcinoma, Esophageal" 20309880 miR-16-2 was associated with lymph node metastasis other hsa-mir-195 "Adenocarcinoma, Esophageal" 20309880 miR-195p was associated with higher pathologic disease stages in patients with esophageal adenocarcinoma other hsa-mir-129-2 Gastric Neoplasms 20331975 We also found that inactivation of SOX4 by siRNA and restoration of miR-129-2 induced apoptosis in gastric cancer cells. other hsa-mir-1296 Prostate Neoplasms 20332239 Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer other hsa-mir-155 Pancreatic Adenocarcinoma 20332664 Aberrant MicroRNA-155 expression is an early event in the multistep progression of pancreatic adenocarcinoma other hsa-mir-21 Neoplasms [unspecific] 20335152 Expression of microRNA-21 in ovarian epithelial carcinoma and its clinical significance other hsa-mir-107 Breast Neoplasms 20348243 "MicroRNAs are also integral components of this gene regulation network because miR-107, miR-424, miR-570, miR-618, and miR-760 are regulated by 17beta-estradiol along with other microRNAs that can target a significant number of transcripts belonging to one or more estrogen-responsive gene clusters." other hsa-mir-424 Breast Neoplasms 20348243 "MicroRNAs are also integral components of this gene regulation network because miR-107, miR-424, miR-570, miR-618, and miR-760 are regulated by 17beta-estradiol along with other microRNAs that can target a significant number of transcripts belonging to one or more estrogen-responsive gene clusters." other hsa-mir-570 Breast Neoplasms 20348243 "MicroRNAs are also integral components of this gene regulation network because miR-107, miR-424, miR-570, miR-618, and miR-760 are regulated by 17beta-estradiol along with other microRNAs that can target a significant number of transcripts belonging to one or more estrogen-responsive gene clusters." other hsa-mir-618 Breast Neoplasms 20348243 "MicroRNAs are also integral components of this gene regulation network because miR-107, miR-424, miR-570, miR-618, and miR-760 are regulated by 17beta-estradiol along with other microRNAs that can target a significant number of transcripts belonging to one or more estrogen-responsive gene clusters." other hsa-mir-760 Breast Neoplasms 20348243 "MicroRNAs are also integral components of this gene regulation network because miR-107, miR-424, miR-570, miR-618, and miR-760 are regulated by 17beta-estradiol along with other microRNAs that can target a significant number of transcripts belonging to one or more estrogen-responsive gene clusters." other hsa-mir-155 Colorectal Carcinoma 20351277 Modulation of mismatch repair and genomic stability by miR-155 other hsa-mir-10b Neoplasms [unspecific] 20351690 Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model other hsa-mir-181a-2 Glioblastoma 20353279 MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients other hsa-mir-181b-1 Glioblastoma 20353279 MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients other hsa-mir-181b-2 Glioblastoma 20353279 MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients other hsa-mir-181c Glioblastoma 20353279 MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients other hsa-mir-181d Glioblastoma 20353279 MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients other hsa-mir-21 Granulosa Cell Tumor 20357270 MicroRNA 21 Blocks Apoptosis in Mouse Periovulatory Granulosa Cells other hsa-mir-9 Brain Disease [unspecific] 20362537 These results identify miR-9 as a novel regulator that coordinates the proliferation and migration of hNPCs. other hsa-mir-204 Head And Neck Neoplasms 20369013 Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis other hsa-mir-122 Hepatitis C Virus Infection 20371461 "miR-122, a major regulatory RNA in liver that fine-tunes the expression of over 100 cellular genes and enhances HCV replication" other hsa-mir-122 Liver Neoplasms 20371461 "miR-122, a major regulatory RNA in liver that fine-tunes the expression of over 100 cellular genes and enhances HCV replication" other hsa-mir-650 Gastric Neoplasms 20381459 we show that miR-650 is involved in lymphatic and distant metastasis in human gastric cancer other hsa-mir-27a Breast Neoplasms 20382698 miR-27a:MicroRNA-27a Indirectly Regulates Estrogen Receptor {alpha} Expression and Hormone Responsiveness in MCF-7 Breast Cancer Cells other hsa-mir-145 Ewing Sarcoma 20382729 EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells. other hsa-mir-146a Inflammation 20384865 "functional role of miR-146a in innate immune, inflammatory response, virus infection and human diseases" other hsa-mir-200a Pancreatic Neoplasms 20388782 miR-200:Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF other hsa-mir-21 Pancreatic Neoplasms 20388782 miR-21:Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF other hsa-mir-199a-1 Ovarian Neoplasms 20400975 "miR-199a:TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214" other hsa-mir-199a-2 Ovarian Neoplasms 20400975 "miR-199a:TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214" other hsa-mir-214 Ovarian Neoplasms 20400975 "miR-214:TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214" other hsa-mir-21 Cardiovascular Diseases [unspecific] 20404348 MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligand other hsa-mir-21 Neoplasms [unspecific] 20404348 miR-21:function of AKT by which it inhibits apoptosis through miR-21-dependent suppression of FasL other hsa-mir-146b Neoplasms [unspecific] 20406109 "miR-146b:potential importance of miR-221, miR-222, and miR-146b in determining the aggressive properties of PTCs" other hsa-mir-221 Neoplasms [unspecific] 20406109 "miR-221:potential importance of miR-221, miR-222, and miR-146b in determining the aggressive properties of PTCs" other hsa-mir-222 Neoplasms [unspecific] 20406109 "miR-222:potential importance of miR-221, miR-222, and miR-146b in determining the aggressive properties of PTCs" other hsa-mir-17 Breast Neoplasms 20406904 microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling other hsa-mir-20a Breast Neoplasms 20406904 microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling other hsa-mir-20b Breast Neoplasms 20406904 microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling other hsa-mir-107 Alzheimer Disease 20413881 MiR-107 is reduced in Alzheimer's disease brain neocortex: validation study. other hsa-mir-296 Atherosclerosis 20415654 Tumor angiogenesis is additionally controlled by miR-296 and miR-378. other hsa-let-7b Neurodegenerative Diseases [unspecific] 20423455 "Interestingly, both miRNAs are capable of binding directly to TDP-43 in different positions: within the miRNA sequence itself (let-7b) or in the hairpin precursor (miR-663)." other hsa-mir-663 Neurodegenerative Diseases [unspecific] 20423455 "Interestingly, both miRNAs are capable of binding directly to TDP-43 in different positions: within the miRNA sequence itself (let-7b) or in the hairpin precursor (miR-663)." other hsa-let-7a-1 "Leukemia, Myeloid, Acute" 20425795 "hsa-let-7a:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-let-7a-2 "Leukemia, Myeloid, Acute" 20425795 "hsa-let-7a:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-let-7a-3 "Leukemia, Myeloid, Acute" 20425795 "hsa-let-7a:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-let-7b "Leukemia, Myeloid, Acute" 20425795 "hsa-let-7b:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-let-7c "Leukemia, Myeloid, Acute" 20425795 "hsa-let-7c:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-let-7d "Leukemia, Myeloid, Acute" 20425795 "hsa-let-7d:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-let-7e "Leukemia, Myeloid, Acute" 20425795 "hsa-let-7e:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-let-7f-1 "Leukemia, Myeloid, Acute" 20425795 "hsa-let-7f:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-let-7f-2 "Leukemia, Myeloid, Acute" 20425795 "hsa-let-7f:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-let-7g "Leukemia, Myeloid, Acute" 20425795 "hsa-let-7g:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-let-7i "Leukemia, Myeloid, Acute" 20425795 "hsa-let-7i:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-mir-126 "Leukemia, Myeloid, Acute" 20425795 "miR-126:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-mir-155 "Leukemia, Myeloid, Acute" 20425795 "miR-155:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-mir-196b "Leukemia, Myeloid, Acute" 20425795 "miR-196b:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-mir-221 "Leukemia, Myeloid, Acute" 20425795 "miR-221:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-mir-98 "Leukemia, Myeloid, Acute" 20425795 "hsa-mir-98:miR-155, miR-221, let-7, miR-126 and miR-196b appear to be associated with particular subtypes." other hsa-mir-34a Colon Neoplasms 20433755 "For instance, miR-34a up-regulation corresponded with a down-regulation of BCL2 protein. Treating Par-4-overexpressing HT29 cells with a miR-34a antagomir functionally reversed both BCL2 down-regulation and apoptosis by 5-FU." other hsa-mir-125b Inflammation 20435889 "The process required to disrupt protein synthesis followed Toll-like receptor 4 (TLR4)-dependent induction of microRNA (miR)-221, miR-579, and miR-125b, which coupled with RNA-binding proteins TTP, AUF1, and TIAR at the 3'-untranslated region to arrest protein synthesis." other hsa-mir-221 Inflammation 20435889 "The process required to disrupt protein synthesis followed Toll-like receptor 4 (TLR4)-dependent induction of microRNA (miR)-221, miR-579, and miR-125b, which coupled with RNA-binding proteins TTP, AUF1, and TIAR at the 3'-untranslated region to arrest protein synthesis." other hsa-mir-579 Inflammation 20435889 "The process required to disrupt protein synthesis followed Toll-like receptor 4 (TLR4)-dependent induction of microRNA (miR)-221, miR-579, and miR-125b, which coupled with RNA-binding proteins TTP, AUF1, and TIAR at the 3'-untranslated region to arrest protein synthesis." other hsa-mir-101-1 "Carcinoma, Hepatocellular" 20444294 miR-101:PKCalpha mediated induction of miR-101 in human hepatoma HepG2 cells other hsa-mir-101-2 "Carcinoma, Hepatocellular" 20444294 miR-101:PKCalpha mediated induction of miR-101 in human hepatoma HepG2 cells other hsa-mir-10a Glioblastoma 20444541 "miR-10a:miR-195, miR-455-3p and miR-10a( *) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells" other hsa-mir-195 Glioblastoma 20444541 "miR-195:miR-195, miR-455-3p and miR-10a( *) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells" other hsa-mir-455 Glioblastoma 20444541 "miR-455-3p:miR-195, miR-455-3p and miR-10a( *) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells" other hsa-mir-10b Neoplasms [unspecific] 20444703 miR-10b:miR-10b targets Tiam1: implications for Rac activation and carcinoma migration other hsa-mir-21 "Carcinoma, Hepatocellular" 20447717 microRNA-21:MicroRNA-21 acts as an oncomir through multiple targets in human hepatocellular carcinoma other hsa-mir-199a-1 Cardiomegaly 20458739 miR-199a:miR-199a is essential for the maintenance of cell size in cardiomyocytes other hsa-mir-199a-1 Cardiovascular Diseases [unspecific] 20458739 miR-199a is essential for the maintenance of cell size in cardiomyocytes other hsa-mir-199a-2 Cardiomegaly 20458739 miR-199a:miR-199a is essential for the maintenance of cell size in cardiomyocytes other hsa-mir-199a-2 Cardiovascular Diseases [unspecific] 20458739 miR-199a is essential for the maintenance of cell size in cardiomyocytes other hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 20460539 miR-21:miR-21 expression correlated with outcome in PDAC patients treated with gemcitabine other hsa-mir-221 Neoplasms [unspecific] 20461750 MiR-221:MiR-221 and MiR-222 alterations in sporadic ovarian carcinoma other hsa-mir-222 Neoplasms [unspecific] 20461750 MiR-222:MiR-221 and MiR-222 alterations in sporadic ovarian carcinoma other hsa-mir-542 Neuroblastoma 20466808 "miR-542-5p:the putative tumor suppressive microRNAs, miR-542-5p and miR-628, were expressed in favorable NBs and virtually absent in unfavorable NBs" other hsa-mir-628 Neuroblastoma 20466808 "miR-628:the putative tumor suppressive microRNAs, miR-542-5p and miR-628, were expressed in favorable NBs and virtually absent in unfavorable NBs" other hsa-mir-140 Osteoarthritis 20466812 "We show that miR-140 regulates cartilage development and homeostasis, and its loss contributes to the development of age-related OA-like changes." other hsa-mir-125b-1 "Cardiomyopathy, Hypertrophic" 20470752 "miR-125b:miR-23a, miR-27b, miR-125b and miR-195 were induced during early hypertrophic growth" other hsa-mir-125b-2 "Cardiomyopathy, Hypertrophic" 20470752 "miR-125b:miR-23a, miR-27b, miR-125b and miR-195 were induced during early hypertrophic growth" other hsa-mir-195 "Cardiomyopathy, Hypertrophic" 20470752 "miR-195:miR-23a, miR-27b, miR-125b and miR-195 were induced during early hypertrophic growth" other hsa-mir-23a "Cardiomyopathy, Hypertrophic" 20470752 "miR-23a:miR-23a, miR-27b, miR-125b and miR-195 were induced during early hypertrophic growth" other hsa-mir-27b "Cardiomyopathy, Hypertrophic" 20470752 "miR-27b:miR-23a, miR-27b, miR-125b and miR-195 were induced during early hypertrophic growth" other hsa-mir-196a-1 Melanoma 20480203 miR-196a:MicroRNA miR-196a is a central regulator of HOX-B7 and BMP4 expression in malignant melanoma other hsa-mir-196a-2 Melanoma 20480203 miR-196a:MicroRNA miR-196a is a central regulator of HOX-B7 and BMP4 expression in malignant melanoma other hsa-mir-100 Adrenal Cortex Neoplasms 20484036 "miR-100:differentially regulated in childhood adrenocortical tumors (ACT), including miR-99a and miR-100" other hsa-mir-99a Adrenal Cortex Neoplasms 20484036 "miR-99a:differentially regulated in childhood adrenocortical tumors (ACT), including miR-99a and miR-100" other hsa-mir-20b "Lymphoma, Mantle-Cell" 20485376 "miR-20b:miR-20b, whose lack of expression distinguished cases with a survival probability of 56% at 60 months" other hsa-mir-26a-1 "Lymphoma, Mantle-Cell" 20485376 miR-26a:NF-kappaB subunit nuclear translocation to be regulated by the expression of miR-26a other hsa-mir-26a-2 "Lymphoma, Mantle-Cell" 20485376 miR-26a:NF-kappaB subunit nuclear translocation to be regulated by the expression of miR-26a other hsa-mir-21 Coronary Artery Disease 20489163 miR-21:We identified a novel miR-21-dependent mechanism of ADMA-mediated APC dysfunction other hsa-mir-196b "Leukemia, Lymphoblastic, Acute, Childhood" 20494936 Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia. other hsa-mir-27b Melanoma 20495621 "we identified miRNAs that are up- and down-regulated in melanoma cells exposed to a hESC microenvironment, such as miR-302a and miR-27b, respectively." other hsa-mir-302a Melanoma 20495621 "we identified miRNAs that are up- and down-regulated in melanoma cells exposed to a hESC microenvironment, such as miR-302a and miR-27b, respectively." other hsa-mir-30a Breast Neoplasms 20498642 Mir-30:Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells other hsa-mir-21 Pancreatic Neoplasms 20498843 microRNA-21:Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer other hsa-mir-520h Neoplasms [unspecific] 20501832 miR-520h:Downregulation of microRNA miR-520h by E1A contributes to anticancer activity other hsa-mir-206 Rhabdomyosarcoma 20502458 MicroRNA-206:MicroRNA-206 expression levels correlate with clinical behaviour of rhabdomyosarcomas other hsa-mir-21 Glioma 20514462 miR-21:Reduction of miR-21 induces glioma cell apoptosis via activating caspase 9 and 3 other hsa-mir-140 Osteoarthritis 20516192 miR-140:miR-140 has a critical and nonredundant role in cartilage development and homeostasis other hsa-mir-26a-1 Hypertrophy 20525681 MiR-26a:stretch or enforced expression of miR-26a induces HASMC hypertrophy other hsa-mir-26a-2 Hypertrophy 20525681 MiR-26a:stretch or enforced expression of miR-26a induces HASMC hypertrophy other hsa-mir-222 Neoplasms [unspecific] 20525881 "miR-222:five miRNAs that negatively control cell proliferation, including miRNA-34a" other hsa-mir-224 Neoplasms [unspecific] 20525881 "miR-224:five miRNAs that negatively control cell proliferation, including miRNA-34a" other hsa-mir-29b-1 Neoplasms [unspecific] 20525881 "miR-29b:five miRNAs that negatively control cell proliferation, including miRNA-34a" other hsa-mir-29b-2 Neoplasms [unspecific] 20525881 "miR-29b:five miRNAs that negatively control cell proliferation, including miRNA-34a" other hsa-mir-34a Neoplasms [unspecific] 20525881 "miR-34a:five miRNAs that negatively control cell proliferation, including miRNA-34a" other hsa-mir-532 Neoplasms [unspecific] 20525881 "miR-532:five miRNAs that negatively control cell proliferation, including miRNA-34a" other hsa-mir-122 "Carcinoma, Hepatocellular" 20527935 miR-122:Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma other hsa-mir-122 Hepatitis C Virus Infection 20527935 miR-122:Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma other hsa-mir-140 Arteriosclerosis Obliterans 20528768 "Global analysis of predicted miRNA targets found significantly reduced expression of genes with target regions compared with those without: hsa-miR-140-3p (P=0.002), hsa-miR-182 (P=0.001), hsa-miR-92a and hsa-miR-92b (P=2.2x10-16)." other hsa-mir-182 Arteriosclerosis Obliterans 20528768 "Global analysis of predicted miRNA targets found significantly reduced expression of genes with target regions compared with those without: hsa-miR-140-3p (P=0.002), hsa-miR-182 (P=0.001), hsa-miR-92a and hsa-miR-92b (P=2.2x10-16)." other hsa-mir-92a Arteriosclerosis Obliterans 20528768 "Global analysis of predicted miRNA targets found significantly reduced expression of genes with target regions compared with those without: hsa-miR-140-3p (P=0.002), hsa-miR-182 (P=0.001), hsa-miR-92a and hsa-miR-92b (P=2.2x10-16)." other hsa-mir-92b Arteriosclerosis Obliterans 20528768 "Global analysis of predicted miRNA targets found significantly reduced expression of genes with target regions compared with those without: hsa-miR-140-3p (P=0.002), hsa-miR-182 (P=0.001), hsa-miR-92a and hsa-miR-92b (P=2.2x10-16)." other hsa-mir-31 Neoplasms [unspecific] 20530680 "miR-31:Concurrent suppression of integrin alpha5, radixin, and RhoA phenocopies the effects of miR-31 on metastasis" other hsa-mir-221 Melanoma 20547861 microRNA-221:Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells other hsa-mir-196b "Leukemia, Lymphocytic, Chronic, B-Cell" 20549547 miR-196b:Potential tumor suppressive function of miR-196b in B-cell lineage acute lymphoblastic leukemia other hsa-mir-125b Bladder Neoplasms 20549700 "Taken together, miR-125b may act as a tumor suppressor in bladder urothelium, and downregulation of miR-125b may contribute to the tumorigenesis of bladder cancer." other hsa-mir-29a "Leukemia, Lymphocytic, Chronic, B-Cell" 20566844 miR-29:dysregulation of miR-29 can contribute to the pathogenesis of indolent B-CLL other hsa-mir-196a Leukemia 20570349 our results identify miR-196a and miR-196b as ERG regulators and implicate a potential role for these miRNAs in acute leukemia. other hsa-mir-196b Leukemia 20570349 our results identify miR-196a and miR-196b as ERG regulators and implicate a potential role for these miRNAs in acute leukemia. other hsa-mir-181a-2 "Carcinoma, Hepatocellular" 20576283 miRNA-181a:Micro-RNA-181a regulates osteopontin-dependent metastatic function in hepatocellular cancer cell lines other hsa-mir-196a Glioma 20601442 Our results suggest that miR-196 may play a role in the malignant progression of gliomas and may be a prognostic predictor in glioblastomas. other hsa-mir-212 Cocaine Abuse 20613834 miR-212:miR-212 signalling has a key role in determining vulnerability to cocaine addiction other hsa-mir-101 Neoplasms [unspecific] 20617180 "Up-regulating miR-101 efficiently reduced the protein levels of DNA-PKcs and ATM in these tumor cells and most importantly, sensitized the tumor cells to radiation in vitro and in vivo." other hsa-mir-1-1 Distal Myopathy 20619221 miR-1:have a profound influence on multiple myopathies other hsa-mir-1-1 Hypertrophy 20619221 miR-1:have a profound influence on multiple myopathies other hsa-mir-1-2 Distal Myopathy 20619221 miR-1:have a profound influence on multiple myopathies other hsa-mir-1-2 Hypertrophy 20619221 miR-1:have a profound influence on multiple myopathies other hsa-mir-133a-1 Distal Myopathy 20619221 miR-133:have a profound influence on multiple myopathies other hsa-mir-133a-1 Hypertrophy 20619221 miR-133:have a profound influence on multiple myopathies other hsa-mir-133a-2 Distal Myopathy 20619221 miR-133:have a profound influence on multiple myopathies other hsa-mir-133a-2 Hypertrophy 20619221 miR-133:have a profound influence on multiple myopathies other hsa-mir-206 Distal Myopathy 20619221 miR-206:have a profound influence on multiple myopathies other hsa-mir-206 Hypertrophy 20619221 miR-206:have a profound influence on multiple myopathies other hsa-mir-141 "Carcinoma, Hepatocellular" 20619223 "miR-141:Hsa-miR-141 and hsa-miR-200c, microRNAs that promote epithelial phenotypes, had significantly higher levels in non-hepatic epithelial tumors" other hsa-mir-200c "Carcinoma, Hepatocellular" 20619223 "miR-200c:Hsa-miR-141 and hsa-miR-200c, microRNAs that promote epithelial phenotypes, had significantly higher levels in non-hepatic epithelial tumors" other hsa-mir-126 Gastric Neoplasms 20619534 miR-126:miR-126 functions as a tumour suppressor in human gastric cancer other hsa-let-7i "Squamous Cell Carcinoma, Lung" 20620595 "let-7i:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC" other hsa-mir-143 Colorectal Carcinoma 20620599 miR-143:MiR-21 and miR-143 expressions were quantified by using the quantitative reverse transcription polymerase chain reaction method other hsa-mir-21 Colorectal Carcinoma 20620599 miR-21:Our results support the hypothesis about oncogenic function of miR-21 other hsa-mir-134 Central Nervous System Embryonal Tumor 20622856 miR-134:A novel pathway regulates memory and plasticity via SIRT1 and miR-134 other hsa-mir-34a Atherosclerosis 20627091 MiR-34a:MicroRNA-34a regulation of endothelial senescence other hsa-mir-34a Cardiovascular Diseases [unspecific] 20627091 MiR-34a:MicroRNA-34a regulation of endothelial senescence other hsa-let-7a-1 Asthma 20630862 let-7a:Proinflammatory role for let-7 microRNAS in experimental asthma other hsa-let-7a-2 Asthma 20630862 let-7a:Proinflammatory role for let-7 microRNAS in experimental asthma other hsa-let-7a-3 Asthma 20630862 let-7a:Proinflammatory role for let-7 microRNAS in experimental asthma other hsa-let-7b Asthma 20630862 let-7b:Proinflammatory role for let-7 microRNAS in experimental asthma other hsa-let-7c Asthma 20630862 let-7c:Proinflammatory role for let-7 microRNAS in experimental asthma other hsa-let-7d Asthma 20630862 let-7d:Proinflammatory role for let-7 microRNAS in experimental asthma other hsa-let-7e Asthma 20630862 let-7e:Proinflammatory role for let-7 microRNAS in experimental asthma other hsa-let-7f-1 Asthma 20630862 let-7f:Proinflammatory role for let-7 microRNAS in experimental asthma other hsa-let-7f-2 Asthma 20630862 let-7f:Proinflammatory role for let-7 microRNAS in experimental asthma other hsa-let-7g Asthma 20630862 let-7g:Proinflammatory role for let-7 microRNAS in experimental asthma other hsa-let-7i Asthma 20630862 let-7i:Proinflammatory role for let-7 microRNAS in experimental asthma other hsa-mir-21 Lung Fibrosis 20643828 miR-21:These experiments demonstrate an important role for miR-21 in fibrotic lung diseases other hsa-mir-16-1 Neoplasms [unspecific] 20668064 miR-16:miR-16 in the regulation of Wip1 phosphatase in the DNA damage response and mammary tumorigenesis other hsa-mir-16-2 Neoplasms [unspecific] 20668064 miR-16:miR-16 in the regulation of Wip1 phosphatase in the DNA damage response and mammary tumorigenesis other hsa-mir-132 Neoplasms [unspecific] 20676106 miR-132:miR-132 was highly expressed in the endothelium of human tumors and hemangiomas other hsa-mir-146a "Carcinoma, Basal Cell" 20680470 These findings suggest that this functional SNP in pre-miR-146a could contribute to ESCC susceptibility and clinical outcome. other hsa-mir-34a Prostate Neoplasms 20687223 MiR-34a:MiR-34a attenuates paclitaxel-resistance of hormone-refractory prostate cancer PC3 cells through direct and indirect mechanisms other hsa-mir-21 "Lymphoma, B-Cell" 20693987 miR-21:OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma other hsa-mir-212 Cocaine Abuse 20711185 miR-212:miR-212 in dorsal striatum may be important in regulating vulnerability to cocaine addiction other hsa-mir-335 Neoplasms [unspecific] 20713524 miR-335:miR-335 activates the p53 tumor suppressor pathway to limit cell proliferation and neoplastic cell transformation other hsa-mir-382 Renal Fibrosis 20716515 The study provided experimental evidence in the form of reciprocal expression at the protein level for a large number of predicted miRNA-target pairs and discovered a novel role of miR-382 and SOD2 in the loss of epithelial characteristics induced by TGF¦Â1. other hsa-mir-125a "Carcinoma, Lung, Non-Small-Cell" 20719190 hsa-miR-125a-5p was poorly-expressed in lung cancer cells and it could enhance lung cancer cell invasion by up-regulating hsa-miR-125a-5p. other hsa-mir-195 Colorectal Carcinoma 20727858 miR-195:microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells other hsa-mir-30b Schizophrenia 20732949 These preliminary findings point to the possibility that disease-related changes in the expression of small noncoding RNAs such as miR-30b in schizophrenia could be influenced by gender and potentially regulated by estrogen signaling. other hsa-mir-145 Myelodysplastic Syndromes 20733155 "Other mouse modeling data suggest that haploinsufficiency of the microRNA genes miR-145 and miR-146a may contribute to the thrombocytosis seen in the 5q- syndrome. Lenalidomide has become an established therapy for the 5q- syndrome, although its precise mode of action remains uncertain." other hsa-mir-146a Myelodysplastic Syndromes 20733155 "Other mouse modeling data suggest that haploinsufficiency of the microRNA genes miR-145 and miR-146a may contribute to the thrombocytosis seen in the 5q- syndrome. Lenalidomide has become an established therapy for the 5q- syndrome, although its precise mode of action remains uncertain." other hsa-mir-34a "Carcinoma, Rectal" 20734047 Satraplatin treatment induces p53-related genes and its direct microRNA target of miR-34a independently. other hsa-mir-205 Prostate Neoplasms 20737563 MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer. other hsa-mir-320a Childhood Leukemia 20807887 "In summary our data suggest that TEL-AML1 might exert its antiapoptotic action at least in part by suppressing miRNA-494 and miRNA-320a, lowering their expression causing enhanced survivin expression." other hsa-mir-494 Childhood Leukemia 20807887 "In summary our data suggest that TEL-AML1 might exert its antiapoptotic action at least in part by suppressing miRNA-494 and miRNA-320a, lowering their expression causing enhanced survivin expression." other hsa-let-7a "Carcinoma, Gastric" 20809749 Lentiviral vector-mediated upregulation of let-7a inhibits gastric carcinoma cell growth in vitro and in vivo. other hsa-mir-146a Ovarian Neoplasms 20810544 Association between hsa-mir-146a genotype and tumor age-of-onset in BRCA1/BRCA2-negative familial breast and ovarian cancer patients. other hsa-mir-151 "Carcinoma, Hepatocellular" 20812359 MicroRNA-151 and its hosting gene FAK (focal adhesion kinase) regulate tumor cell migration and spreading of hepatocellular carcinoma. other hsa-mir-451 Glioblastoma 20816946 MiRNA-451 plays a role as tumor suppressor in human glioma cells. other hsa-mir-145 Breast Neoplasms 20818426 miR-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness. other hsa-mir-200a "Carcinoma, Nasopharyngeal" 20826811 Our findings reveal for the first time the function of miR-200a in shifting nasopharyngeal carcinoma cell states via a reversible process coined as epithelial-mesenchymal to stem-like transition through differential and specific mechanisms. other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 20832755 miR-21:Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21 other hsa-mir-210 Myocardial Infarction 20837903 "miR-210:MicroRNA-210 can improve angiogenesis, inhibit apoptosis, and improve cardiac function in a murine model of myocardial infarction." other hsa-mir-16 Leukemia 20839343 "The murine disease is linked to a genetic abnormality in microRNA mir-15a/16-1 locus, resulting in decreased mature miR-15a/16." other hsa-mir-146a Rheumatoid Arthritis 20840794 These results indicated that miR-146a was associated with IL-17 expression in the PBMC and synovium in RA patients. There is the possibility that miR-146a participates in the IL-17 expression. other hsa-mir-17 "Leukemia, Lymphoblastic" 20855495 "NKX3.1 is necessary for T-ALL proliferation, can partially restore proliferation in TAL1 knockdown cells, and directly regulates miR-17-92." other hsa-mir-18 "Leukemia, Lymphoblastic" 20855495 "NKX3.1 is necessary for T-ALL proliferation, can partially restore proliferation in TAL1 knockdown cells, and directly regulates miR-17-92." other hsa-mir-19a "Leukemia, Lymphoblastic" 20855495 "NKX3.1 is necessary for T-ALL proliferation, can partially restore proliferation in TAL1 knockdown cells, and directly regulates miR-17-92." other hsa-mir-19b-1 "Leukemia, Lymphoblastic" 20855495 "NKX3.1 is necessary for T-ALL proliferation, can partially restore proliferation in TAL1 knockdown cells, and directly regulates miR-17-92." other hsa-mir-20a "Leukemia, Lymphoblastic" 20855495 "NKX3.1 is necessary for T-ALL proliferation, can partially restore proliferation in TAL1 knockdown cells, and directly regulates miR-17-92." other hsa-mir-92-1 "Leukemia, Lymphoblastic" 20855495 "NKX3.1 is necessary for T-ALL proliferation, can partially restore proliferation in TAL1 knockdown cells, and directly regulates miR-17-92." other hsa-mir-223 "Leukemia, Lymphocytic, Chronic, B-Cell" 20862275 "miR-223:ZAP70, LPL, CLLU1, microRNA-29c and microRNA-223 were measured by real time PCR in a cohort of 170 patients" other hsa-mir-29c "Leukemia, Lymphocytic, Chronic, B-Cell" 20862275 "miR-29c:ZAP70, LPL, CLLU1, microRNA-29c and microRNA-223 were measured by real time PCR in a cohort of 170 patients" other hsa-mir-22 Ovarian Neoplasms 20869762 miR-22:miR-22 might be involved in inhibiting ovarian cancer metastasis other hsa-mir-380 Neuroblastoma 20871609 In vivo delivery of a miR-380-5p antagonist decreases tumor size in an orthotopic mouse model of neuroblastoma. other hsa-mir-130b Prostate Neoplasms 20875868 miR-130b:The hsa-miR-130b also shows a high variance between samples. other hsa-mir-122 Lipid Metabolism Disorder 20880716 "In addition to miR-33, miR-122 and miR-370 have been shown to play important roles in regulating cholesterol and fatty acid metabolism." other hsa-mir-33 Lipid Metabolism Disorder 20880716 "In addition to miR-33, miR-122 and miR-370 have been shown to play important roles in regulating cholesterol and fatty acid metabolism." other hsa-mir-370 Lipid Metabolism Disorder 20880716 "In addition to miR-33, miR-122 and miR-370 have been shown to play important roles in regulating cholesterol and fatty acid metabolism." other hsa-mir-146b Colorectal Carcinoma 20881268 miR-146b-3p and miR-486-5p are more abundant in KRAS mutated samples after cetuximab treatment respect to wild-type ones other hsa-mir-486 Colorectal Carcinoma 20881268 miR-146b-3p and miR-486-5p are more abundant in KRAS mutated samples after cetuximab treatment respect to wild-type ones other hsa-mir-103 Metabolic Syndrome 20886002 "Interestingly, a strong correlation was observed between miR-103 and -107 expression, as well as miR-221 and -222 in both experiments." other hsa-mir-143 Metabolic Syndrome 20886002 "Interestingly, a strong correlation was observed between miR-103 and -107 expression, as well as miR-221 and -222 in both experiments." other hsa-mir-221 Metabolic Syndrome 20886002 "Interestingly, a strong correlation was observed between miR-103 and -107 expression, as well as miR-221 and -222 in both experiments." other hsa-mir-222 Metabolic Syndrome 20886002 "Interestingly, a strong correlation was observed between miR-103 and -107 expression, as well as miR-221 and -222 in both experiments." other hsa-mir-130b Prostate Neoplasms 20890088 We recommend using hsa-miR-130b or the geometric mean of hsa-miR-130b and small RNA RNU6-2 for normalization in miRNA expression studies of prostate cancer. other hsa-mir-339 Breast Neoplasms 20932331 MiR-339-5p inhibits breast cancer cell migration and invasion in vitro and may be a potential biomarker for breast cancer prognosis. other hsa-mir-17 Glioblastoma 20940405 "Together, our results define a pathway in which c-Myc activation of miR-17?92 attenuates the TGF¦Â signaling pathway to shut down clusterin expression, thereby stimulating angiogenesis and tumor cell growth." other hsa-mir-18 Glioblastoma 20940405 "Together, our results define a pathway in which c-Myc activation of miR-17?92 attenuates the TGF¦Â signaling pathway to shut down clusterin expression, thereby stimulating angiogenesis and tumor cell growth." other hsa-mir-19a Glioblastoma 20940405 "Together, our results define a pathway in which c-Myc activation of miR-17?92 attenuates the TGF¦Â signaling pathway to shut down clusterin expression, thereby stimulating angiogenesis and tumor cell growth." other hsa-mir-19b-1 Glioblastoma 20940405 "Together, our results define a pathway in which c-Myc activation of miR-17?92 attenuates the TGF¦Â signaling pathway to shut down clusterin expression, thereby stimulating angiogenesis and tumor cell growth." other hsa-mir-20a Glioblastoma 20940405 "Together, our results define a pathway in which c-Myc activation of miR-17?92 attenuates the TGF¦Â signaling pathway to shut down clusterin expression, thereby stimulating angiogenesis and tumor cell growth." other hsa-mir-92-1 Glioblastoma 20940405 "Together, our results define a pathway in which c-Myc activation of miR-17?92 attenuates the TGF¦Â signaling pathway to shut down clusterin expression, thereby stimulating angiogenesis and tumor cell growth." other hsa-mir-192 Multiple Myeloma 20951946 "Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development" other hsa-mir-194-1 Multiple Myeloma 20951946 "Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development" other hsa-mir-194-2 Multiple Myeloma 20951946 "Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development" other hsa-mir-215 Multiple Myeloma 20951946 "Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development" other hsa-mir-141 Melanoma 20957176 "Overall our findings call into question the general role of miR-200 in suppressing invasion and metastasis, and highlight novel distinguishing characteristics of individual miR-200 family members." other hsa-mir-200a Melanoma 20957176 "Overall our findings call into question the general role of miR-200 in suppressing invasion and metastasis, and highlight novel distinguishing characteristics of individual miR-200 family members." other hsa-mir-200b Melanoma 20957176 "Overall our findings call into question the general role of miR-200 in suppressing invasion and metastasis, and highlight novel distinguishing characteristics of individual miR-200 family members." other hsa-mir-200c Melanoma 20957176 "Overall our findings call into question the general role of miR-200 in suppressing invasion and metastasis, and highlight novel distinguishing characteristics of individual miR-200 family members." other hsa-mir-429 Melanoma 20957176 "Overall our findings call into question the general role of miR-200 in suppressing invasion and metastasis, and highlight novel distinguishing characteristics of individual miR-200 family members." other hsa-mir-1 Myocardial Infarction 20959496 "Studies using various in vivo, ex vivo, and in vitro models have suggested the possible involvement of miR-1, miR-21, miR-29, miR-92a,miR-133, miR-199a, and miR-320 in ischemia-reperfusion injury and/or remodeling after myocardial infarction." other hsa-mir-133 Myocardial Infarction 20959496 "Studies using various in vivo, ex vivo, and in vitro models have suggested the possible involvement of miR-1, miR-21, miR-29, miR-92a,miR-133, miR-199a, and miR-320 in ischemia-reperfusion injury and/or remodeling after myocardial infarction." other hsa-mir-199a Myocardial Infarction 20959496 "Studies using various in vivo, ex vivo, and in vitro models have suggested the possible involvement of miR-1, miR-21, miR-29, miR-92a,miR-133, miR-199a, and miR-320 in ischemia-reperfusion injury and/or remodeling after myocardial infarction." other hsa-mir-21 Myocardial Infarction 20959496 "Studies using various in vivo, ex vivo, and in vitro models have suggested the possible involvement of miR-1, miR-21, miR-29, miR-92a,miR-133, miR-199a, and miR-320 in ischemia-reperfusion injury and/or remodeling after myocardial infarction." other hsa-mir-29 Myocardial Infarction 20959496 "Studies using various in vivo, ex vivo, and in vitro models have suggested the possible involvement of miR-1, miR-21, miR-29, miR-92a,miR-133, miR-199a, and miR-320 in ischemia-reperfusion injury and/or remodeling after myocardial infarction." other hsa-mir-320 Myocardial Infarction 20959496 "Studies using various in vivo, ex vivo, and in vitro models have suggested the possible involvement of miR-1, miR-21, miR-29, miR-92a,miR-133, miR-199a, and miR-320 in ischemia-reperfusion injury and/or remodeling after myocardial infarction." other hsa-mir-92a Myocardial Infarction 20959496 "Studies using various in vivo, ex vivo, and in vitro models have suggested the possible involvement of miR-1, miR-21, miR-29, miR-92a,miR-133, miR-199a, and miR-320 in ischemia-reperfusion injury and/or remodeling after myocardial infarction." other hsa-mir-145 Leukemia 20962326 "As evidence that this subset of miRNAs is relevant to leukemia, we show that loss of 2 miRNAs identified in our analysis, miR-145 and miR-146a, results in leukemia in a mouse model." other hsa-mir-146a Leukemia 20962326 "As evidence that this subset of miRNAs is relevant to leukemia, we show that loss of 2 miRNAs identified in our analysis, miR-145 and miR-146a, results in leukemia in a mouse model." other hsa-let-7i "Carcinoma, Renal Cell" 20964835 "This pattern of regulation was also seen in renal cancer tissue for several of these miRNAs (miR-210, miR-155, let-7i and members of the miR-17-92 cluster) when compared with normal tissue." other hsa-mir-155 "Carcinoma, Renal Cell" 20964835 "This pattern of regulation was also seen in renal cancer tissue for several of these miRNAs (miR-210, miR-155, let-7i and members of the miR-17-92 cluster) when compared with normal tissue." other hsa-mir-17 "Carcinoma, Renal Cell" 20964835 "This pattern of regulation was also seen in renal cancer tissue for several of these miRNAs (miR-210, miR-155, let-7i and members of the miR-17-92 cluster) when compared with normal tissue." other hsa-mir-18 "Carcinoma, Renal Cell" 20964835 "This pattern of regulation was also seen in renal cancer tissue for several of these miRNAs (miR-210, miR-155, let-7i and members of the miR-17-92 cluster) when compared with normal tissue." other hsa-mir-19a "Carcinoma, Renal Cell" 20964835 "This pattern of regulation was also seen in renal cancer tissue for several of these miRNAs (miR-210, miR-155, let-7i and members of the miR-17-92 cluster) when compared with normal tissue." other hsa-mir-19b-1 "Carcinoma, Renal Cell" 20964835 "This pattern of regulation was also seen in renal cancer tissue for several of these miRNAs (miR-210, miR-155, let-7i and members of the miR-17-92 cluster) when compared with normal tissue." other hsa-mir-20a "Carcinoma, Renal Cell" 20964835 "This pattern of regulation was also seen in renal cancer tissue for several of these miRNAs (miR-210, miR-155, let-7i and members of the miR-17-92 cluster) when compared with normal tissue." other hsa-mir-210 "Carcinoma, Renal Cell" 20964835 "This pattern of regulation was also seen in renal cancer tissue for several of these miRNAs (miR-210, miR-155, let-7i and members of the miR-17-92 cluster) when compared with normal tissue." other hsa-mir-92-1 "Carcinoma, Renal Cell" 20964835 "This pattern of regulation was also seen in renal cancer tissue for several of these miRNAs (miR-210, miR-155, let-7i and members of the miR-17-92 cluster) when compared with normal tissue." other hsa-mir-199a-1 Heart Failure 20965886 Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart other hsa-mir-199a-2 Heart Failure 20965886 Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart other hsa-mir-17 Neuroblastoma 20980091 "Mir-21, an established oncomir in a variety of cancer types, became strongly up-regulated upon MYCN knockdown and the subsequent differentiation." other hsa-mir-210 "Squamous Cell Carcinoma, Esophageal" 21044961 "Taken together, our findings show an important role for miR-210 as a tumor-suppressive microRNA with effects on cancer cell proliferation." other hsa-mir-141 Ovarian Neoplasms 21051560 "In conclusion, miR-200 family members(200a,200b,200c,141,429) affect the final ¦Â-tubulin III protein content of ovarian carcinomas. Furthermore, these microRNAs might constitute the biomarkers of response to paclitaxel-based treatments and relapse/progression of advanced stage ovarian carcinoma patients." other hsa-mir-200a Ovarian Neoplasms 21051560 "In conclusion, miR-200 family members(200a,200b,200c,141,429) affect the final ¦Â-tubulin III protein content of ovarian carcinomas. Furthermore, these microRNAs might constitute the biomarkers of response to paclitaxel-based treatments and relapse/progression of advanced stage ovarian carcinoma patients." other hsa-mir-200b Ovarian Neoplasms 21051560 "In conclusion, miR-200 family members(200a,200b,200c,141,429) affect the final ¦Â-tubulin III protein content of ovarian carcinomas. Furthermore, these microRNAs might constitute the biomarkers of response to paclitaxel-based treatments and relapse/progression of advanced stage ovarian carcinoma patients." other hsa-mir-200c Ovarian Neoplasms 21051560 "In conclusion, miR-200 family members(200a,200b,200c,141,429) affect the final ¦Â-tubulin III protein content of ovarian carcinomas. Furthermore, these microRNAs might constitute the biomarkers of response to paclitaxel-based treatments and relapse/progression of advanced stage ovarian carcinoma patients." other hsa-mir-429 Ovarian Neoplasms 21051560 "In conclusion, miR-200 family members(200a,200b,200c,141,429) affect the final ¦Â-tubulin III protein content of ovarian carcinomas. Furthermore, these microRNAs might constitute the biomarkers of response to paclitaxel-based treatments and relapse/progression of advanced stage ovarian carcinoma patients." other hsa-mir-34a Melanoma 21051724 The authors' previous studies on miR-34a showed that miRNA can influence the growth of uveal melanoma cells. other hsa-mir-31 Colon Neoplasms 21062447 "Suppression of microRNA-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells." other hsa-mir-203 "Carcinoma, Rectal" 21063914 miR-203 may be related to the proliferation and invasion of gastric and colorectal cancers. other hsa-let-7b Melanoma 21087605 "Taken together, the present study identifies let-7b as a tumor suppressor that represses cancer cell proliferation and migration as well as tumor metastasis in mouse melanoma cells." other hsa-let-7a Lung Neoplasms 21097396 Construction of let-7a expression plasmid and its inhibitory effect on k-Ras protein in A549 lung cancer cells other hsa-mir-20a Lymphoma 21114763 The pro-senescence role of miR-20a and miR-290 in MEF is apparently in contrast with their proliferative role in tumour and ES cells. other hsa-mir-584 "Carcinoma, Renal Cell, Clear-Cell" 21119662 Tumour suppressor microRNA-584 directly targets oncogene Rock-1 and decreases invasion ability in human clear cell renal cell carcinoma. other hsa-let-7a Ovarian Neoplasms 21122376 "Bioinformatic analysis indicated that let-7a, let-7e, let-7f, miR-22 and miR-886-5p may be involved in cancer invasion and metastasis." other hsa-let-7e Ovarian Neoplasms 21122376 "Bioinformatic analysis indicated that let-7a, let-7e, let-7f, miR-22 and miR-886-5p may be involved in cancer invasion and metastasis." other hsa-let-7f Ovarian Neoplasms 21122376 "Bioinformatic analysis indicated that let-7a, let-7e, let-7f, miR-22 and miR-886-5p may be involved in cancer invasion and metastasis." other hsa-mir-22 Ovarian Neoplasms 21122376 "Bioinformatic analysis indicated that let-7a, let-7e, let-7f, miR-22 and miR-886-5p may be involved in cancer invasion and metastasis." other hsa-mir-886 Ovarian Neoplasms 21122376 "Bioinformatic analysis indicated that let-7a, let-7e, let-7f, miR-22 and miR-886-5p may be involved in cancer invasion and metastasis." other hsa-mir-203 "Carcinoma, Endometrial" 21125666 "In addition, miR-23b and miR-29c, which are involved in the inhibition of mesenchymal markers, and miR-203, which is involved in the inhibition of cell stemness" other hsa-mir-23b "Carcinoma, Endometrial" 21125666 "In addition, miR-23b and miR-29c, which are involved in the inhibition of mesenchymal markers, and miR-203, which is involved in the inhibition of cell stemness" other hsa-mir-29c "Carcinoma, Endometrial" 21125666 "In addition, miR-23b and miR-29c, which are involved in the inhibition of mesenchymal markers, and miR-203, which is involved in the inhibition of cell stemness" other hsa-mir-192 Neoplasms [unspecific] 21128228 "The meta-analysis also revealed some novel tumor-related miRNAs such as hsa-miR-144, hsa-miR-130b, hsa-miR-132, hsa-miR-154, hsa-miR-192 and hsa-miR-345" other hsa-mir-34a Cervical Neoplasms 21128241 "In summary, our study demonstrates an intimate connection among oncogenic HPV E6,p53, miR-34a and p18Ink4c and identifies p18Ink4c as a possible biomarker for cervical cancer." other hsa-mir-21 Breast Neoplasms 21131358 Induction of MIR-21 by retinoic acid in estrogen-receptor-positive breast carcinoma cells: biological correlates and molecular targets other hsa-mir-373 Prostate Neoplasms 21139802 "The oncogenic mi-croRNAs, miR-373 and miR-520c interact with CD44 in Prostate Cancer" other hsa-mir-520c Prostate Neoplasms 21139802 "The oncogenic mi-croRNAs, miR-373 and miR-520c interact with CD44 in Prostate Cancer" other hsa-let-7a-1 Prostate Neoplasms 21148031 RPS2 control let-7a expression in human prostate cancer. other hsa-mir-92a-1 Esophageal Neoplasms 21148309 microRNA-92a promotes lymph node metastasis of human esophageal squamous cell carcinoma via E-cadherin. other hsa-mir-92a-2 Esophageal Neoplasms 21148309 microRNA-92a promotes lymph node metastasis of human esophageal squamous cell carcinoma via E-cadherin. other hsa-mir-206 Lung Neoplasms 21157919 MicroRNA-206 Is Associated With Invasion and Metastasis of Lung Cancer. other hsa-mir-143 Pancreatic Neoplasms 21159815 Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. other hsa-mir-145 Pancreatic Neoplasms 21159815 Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. other hsa-mir-203 Prostate Neoplasms 21159887 miR-203 expression is specifically attenuated in bone metastatic prostate cancer suggesting a fundamental anti-metastatic role for this miRNA other hsa-mir-138-2 Panic Disorder 21168126 "Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 Are Associated with Panic Disorder and Regulate Several Anxiety Candidate Genes and Related Pathways." other hsa-mir-148a Panic Disorder 21168126 "Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 Are Associated with Panic Disorder and Regulate Several Anxiety Candidate Genes and Related Pathways." other hsa-mir-22 Panic Disorder 21168126 "Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 Are Associated with Panic Disorder and Regulate Several Anxiety Candidate Genes and Related Pathways." other hsa-mir-488 Panic Disorder 21168126 "Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 Are Associated with Panic Disorder and Regulate Several Anxiety Candidate Genes and Related Pathways." other hsa-mir-101-1 Alzheimer Disease 21172309 MicroRNA-101 downregulates Alzheimer's amyloid-beta precursor protein levels in human cell cultures and is differentially expressed. other hsa-let-7i Liver Neoplasms 21176238 let-7i* is overexpressed in side population of HCC cells compared to fetal liver cells other hsa-mir-155 Endometrial Neoplasms 21176560 "Hsa-miR-155 may play an important role in the proliferation, and metastasis of endometrial cancer, which may be a indicator in the diagnosis and prognosis of endometrial cancer and may be used as a predictive biomarker." other hsa-mir-30a Medulloblastoma 21177782 miR-34a confers chemosensitivity through modulation of MAGE-A and p53 in medulloblastoma. other hsa-mir-30a Glioblastoma 21178384 the transcriptional BDNF inhibitor miR-30a-5p was also overexpressed at 6 and 12 h of paroxetine incubation other hsa-mir-135a Heart Failure 21185128 Possible involvement of microRNAs (miR-135a?) in heart failure associated with 25bp deletion in MYBPC3 (cardiac myosin binding protein C) gene. other hsa-mir-126 Coronary Artery Disease 21195052 Coronary Artery Disease other hsa-mir-130a Coronary Artery Disease 21195052 Coronary Artery Disease other hsa-mir-221 Coronary Artery Disease 21195052 Coronary Artery Disease other hsa-mir-222 Coronary Artery Disease 21195052 Coronary Artery Disease other hsa-mir-92a-1 Coronary Artery Disease 21195052 Coronary Artery Disease other hsa-mir-92a-2 Coronary Artery Disease 21195052 Coronary Artery Disease other hsa-mir-19a "Lymphoma, B-Cell" 21200023 diffuse large B-cell lymphoma other hsa-mir-19b-1 "Lymphoma, B-Cell" 21200023 diffuse large B-cell lymphoma other hsa-mir-19b-2 "Lymphoma, B-Cell" 21200023 diffuse large B-cell lymphoma other hsa-mir-21 "Lymphoma, B-Cell" 21200023 diffuse large B-cell lymphoma other hsa-mir-92a-1 "Lymphoma, B-Cell" 21200023 diffuse large B-cell lymphoma other hsa-mir-92a-2 "Lymphoma, B-Cell" 21200023 diffuse large B-cell lymphoma other hsa-mir-17 Prostate Neoplasms 21203553 miR-17* Suppresses Tumorigenicity of Prostate Cancer by Inhibiting Mitochondrial Antioxidant Enzymes. other hsa-mir-100 Prostate Neoplasms 21212412 miR-99 family of microRNAs suppresses the expression of prostate specific antigen and prostate cancer cell proliferation. other hsa-mir-99a Prostate Neoplasms 21212412 miR-99 family of microRNAs suppresses the expression of prostate specific antigen and prostate cancer cell proliferation. other hsa-mir-99b Prostate Neoplasms 21212412 miR-99 family of microRNAs suppresses the expression of prostate specific antigen and prostate cancer cell proliferation. other hsa-mir-153-1 Glioblastoma 21213215 Chromatin-modifying drugs induce miRNA-153 expression to suppress Irs-2 in glioblastoma cell lines other hsa-mir-145 Ewing Sarcoma 21217773 Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcoma. other hsa-mir-143 Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-145 Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-17 Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-18 Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-192 Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-194 Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-19a Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-19b-1 Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-20a Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-21 Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-215 Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-34 Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-7 Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-92-1 Gastrointestinal Neoplasms 21219233 "The review focuses on the role of specific miRNAs (miR-192/194/215 and miR-7) in the differentiation of gastrointestinal epithelium and on the role of tumor-suppressive (miR-34, miR-143, miR-145) and oncogenic miRNAs (miR-21,miR-17-92 cluster) in gastrointestinal tumors." other hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 21219656 The prognostic impact of miR-155 depends on histological subtype and nodal status in NSCLC. other hsa-mir-221 "Squamous Cell Carcinoma, Oral" 21226887 miR-221 and miR-222 expression increased the growth and tumorigenesis of oral carcinoma cells. other hsa-mir-222 "Squamous Cell Carcinoma, Oral" 21226887 miR-221 and miR-222 expression increased the growth and tumorigenesis of oral carcinoma cells. other hsa-mir-200a Neoplasms [unspecific] 21237487 "Down-regulation of microRNAs of the miR-200 family and miR-205, and an altered expression of classic and desmosomal cadherins in spindle cell carcinoma of the head and neck-hallmark of epithelial-mesenchymal transition." other hsa-mir-200b Neoplasms [unspecific] 21237487 "Down-regulation of microRNAs of the miR-200 family and miR-205, and an altered expression of classic and desmosomal cadherins in spindle cell carcinoma of the head and neck-hallmark of epithelial-mesenchymal transition." other hsa-mir-200c Neoplasms [unspecific] 21237487 "Down-regulation of microRNAs of the miR-200 family and miR-205, and an altered expression of classic and desmosomal cadherins in spindle cell carcinoma of the head and neck-hallmark of epithelial-mesenchymal transition." other hsa-mir-205 Neoplasms [unspecific] 21237487 "Down-regulation of microRNAs of the miR-200 family and miR-205, and an altered expression of classic and desmosomal cadherins in spindle cell carcinoma of the head and neck-hallmark of epithelial-mesenchymal transition." other hsa-mir-378a Neoplasms [unspecific] 21242960 Myc/miR-378/TOB2/cyclin D1 functional module regulates oncogenic transformation. other hsa-mir-23b Urinary Bladder Cancer 21242962 Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53/microRNA-23b/urokinase-type plasminogen activator pathway. other hsa-mir-148a Esophageal Neoplasms 21246413 Mir-148a Improves Response to Chemotherapy in Sensitive and Resistant Oesophageal Adenocarcinoma and Squamous Cell Carcinoma Cells. other hsa-mir-148a "Squamous Cell Carcinoma, Esophageal" 21246413 Mir-148a Improves Response to Chemotherapy in Sensitive and Resistant Oesophageal Adenocarcinoma and Squamous Cell Carcinoma Cells. other hsa-let-7a Retinoblastoma 21247883 "E2F4 binding sites also occurred near regulatory elements for miRNAs such as let-7a and mir-17, suggestive of regulation of miRNAs by E2F4. Taken together, our genome-wide analysis provided evidence of versatile roles of E2F4 and insights into its functions." other hsa-mir-17 Retinoblastoma 21247883 "E2F4 binding sites also occurred near regulatory elements for miRNAs such as let-7a and mir-17, suggestive of regulation of miRNAs by E2F4. Taken together, our genome-wide analysis provided evidence of versatile roles of E2F4 and insights into its functions." other hsa-mir-200c Esophageal Neoplasms 21248297 Overexpression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway. other hsa-mir-146a "Diabetes Mellitus, Type 2" 21249428 Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes. other hsa-mir-184 "Carcinoma, Renal Cell" 21253009 "miR-210, miR-184 and miR-206) play pivotal roles in ccRCC development" other hsa-mir-206 "Carcinoma, Renal Cell" 21253009 "miR-210, miR-184 and miR-206) play pivotal roles in ccRCC development" other hsa-mir-210 "Carcinoma, Renal Cell" 21253009 "miR-210, miR-184 and miR-206) play pivotal roles in ccRCC development" other hsa-mir-146a Periodontal Diseases 21263019 Polymicrobial Infection with Periodontal Pathogens Specifically enhances miR-146a in ApoE-/- Mice during Experimental Periodontal Disease. other hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 21263248 "In conclusion, the relative quantification of miR-205 and miR-21 seems to be a promising diagnostic tool" other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 21263248 "In conclusion, the relative quantification of miR-205 and miR-21 seems to be a promising diagnostic tool" other hsa-mir-34a Neuroblastoma 21266077 This microRNA is a potent tumor suppressor molecule in vivo in neuroblastoma. other hsa-mir-1258 Breast Neoplasms 21266359 Suppresses Breast Cancer Brain Metastasis by Targeting Heparanase. other hsa-mir-146b Glioblastoma 21266476 Induction of miR-146b by PDGF-BB is modulated via MAPK-dependent induction of c-fos. other hsa-mir-146b Ovarian Neoplasms 21266476 Induction of miR-146b by PDGF-BB is modulated via MAPK-dependent induction of c-fos. other hsa-mir-143 Colon Neoplasms 21276449 The ecotropic viral integration site 1 oncoprotein (Evi1) is a transcriptional suppressor of the miRNA-143 gene. other hsa-mir-429 Ovarian Neoplasms 21277012 Overexpression of miR-429 induces mesenchymal-to-epithelial transition (MET) in metastatic ovarian cancer cells. other hsa-mir-21 Colon Neoplasms 21279518 PDCD4 nuclear loss inversely correlates with miR-21 levels in colon carcinogenesis. other hsa-mir-203 Rheumatoid Arthritis 21279994 elevated levels of miR-203 lead to increased secretion of MMP-1 and IL-6 via the NF-kB pathway and thereby contribute to the activated phenotype of synovial fibroblasts in RA. other hsa-mir-155 Cystic Fibrosis 21282106 Elevated miR-155 promotes inflammation in cystic fibrosis by driving hyper-expression of interleukin-8. other hsa-mir-155 Inflammation 21282106 Elevated miR-155 promotes inflammation in cystic fibrosis by driving hyper-expression of interleukin-8. other hsa-mir-24-1 Inflammation 21282569 "Role of miR-204 in the regulation of apoptosis, ER stress response, and inflammation in human trabecular meshwork cells." other hsa-mir-24-2 Inflammation 21282569 "Role of miR-204 in the regulation of apoptosis, ER stress response, and inflammation in human trabecular meshwork cells." other hsa-mir-199a-1 Liver Cirrhosis 21283674 "In both the mouse and human studies, the expression levels of miR-199a, 199a*, 200a, and 200b were positively and significantly correlated to the progressed liver fibrosis." other hsa-mir-199a-2 Liver Cirrhosis 21283674 "In both the mouse and human studies, the expression levels of miR-199a, 199a*, 200a, and 200b were positively and significantly correlated to the progressed liver fibrosis." other hsa-mir-200a Liver Cirrhosis 21283674 "In both the mouse and human studies, the expression levels of miR-199a, 199a*, 200a, and 200b were positively and significantly correlated to the progressed liver fibrosis." other hsa-mir-200b Liver Cirrhosis 21283674 "In both the mouse and human studies, the expression levels of miR-199a, 199a*, 200a, and 200b were positively and significantly correlated to the progressed liver fibrosis." other hsa-mir-106b Colon Neoplasms 21283757 Butyrate-induced p21 protein expression was dampened by treatment with a miR-106b mimic. other hsa-mir-200a Pancreatic Neoplasms 21285251 DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism. other hsa-mir-33a Inflammation 21285396 "miR-33 reduces RIP140 coactivator activity for NF-kB, which is supported by the reduction in NF-kB reporter activity and the inflammatory potential in macrophages." other hsa-mir-33b Inflammation 21285396 "miR-33 reduces RIP140 coactivator activity for NF-kB, which is supported by the reduction in NF-kB reporter activity and the inflammatory potential in macrophages." other hsa-mir-375 Obesity 21291493 "Taken together, these data suggest that miR-375 promotes 3T3-L1 adipocyte differentiation, possibly through modulating the ERK-PPAR¦Ã2-aP2 pathway." other hsa-let-7a-1 Head And Neck Neoplasms 21292542 MicroRNA let-7a represses chemoresistance and tumourigenicity in head and neck cancer via stem-like properties ablation. other hsa-let-7a-2 Head And Neck Neoplasms 21292542 MicroRNA let-7a represses chemoresistance and tumourigenicity in head and neck cancer via stem-like properties ablation. other hsa-let-7a-3 Head And Neck Neoplasms 21292542 MicroRNA let-7a represses chemoresistance and tumourigenicity in head and neck cancer via stem-like properties ablation. other hsa-mir-193a "Squamous Cell Carcinoma, Head and Neck" 21293058 "miR-193a-5p, expression of which was repressed by p63, was activated by proapoptotic p73 isoforms in both normal cells and tumor cells in vivo." other hsa-mir-200c Head And Neck Neoplasms 21294122 MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells. other hsa-mir-200c "Squamous Cell Carcinoma, Head and Neck" 21294122 MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells. other hsa-let-7e "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-let-7f-1 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-let-7f-2 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-100 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-103a-1 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-103a-2 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-107 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-1202 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-125a "Carcinoma, Hepatocellular" 21298008 miR-125a-5p recurence related other hsa-mir-125b-1 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-125b-2 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-126 "Carcinoma, Hepatocellular" 21298008 miR-126* recurence related other hsa-mir-129-1 "Carcinoma, Hepatocellular" 21298008 miR-129-5p recurence related other hsa-mir-129-2 "Carcinoma, Hepatocellular" 21298008 miR-129-5p recurence related other hsa-mir-140 "Carcinoma, Hepatocellular" 21298008 miR-140-3p recurence related other hsa-mir-142 "Carcinoma, Hepatocellular" 21298008 miR-142-3p recurence related other hsa-mir-145 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-148a "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-18a "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-18b "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-191 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-195 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-21 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-22 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-221 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-222 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-23a "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-24-1 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-24-2 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-27a "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-362 "Carcinoma, Hepatocellular" 21298008 miR-362-3p recurence related other hsa-mir-378a "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-425 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-497 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-96 "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-99a "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-99b "Carcinoma, Hepatocellular" 21298008 recurence related other hsa-mir-206 Breast Neoplasms 21302623 miR-206 may suppress invasion and migration of MDA-MB-231 cells in vitro partly via regulating actin cytoskeleton remodelling such as filopodia formation other hsa-mir-146b Asthma 21305051 "Inverse correlation with the expression of potential mRNA targets identified mmu-miR-146b, -223, -29b, -29c, -483, -574-5p, -672 and -690 as the best candidates for an active implication in asthma pathogenesis. " other hsa-mir-223 Asthma 21305051 "Inverse correlation with the expression of potential mRNA targets identified mmu-miR-146b, -223, -29b, -29c, -483, -574-5p, -672 and -690 as the best candidates for an active implication in asthma pathogenesis. " other hsa-mir-29b Asthma 21305051 "Inverse correlation with the expression of potential mRNA targets identified mmu-miR-146b, -223, -29b, -29c, -483, -574-5p, -672 and -690 as the best candidates for an active implication in asthma pathogenesis. " other hsa-mir-29c Asthma 21305051 "Inverse correlation with the expression of potential mRNA targets identified mmu-miR-146b, -223, -29b, -29c, -483, -574-5p, -672 and -690 as the best candidates for an active implication in asthma pathogenesis. " other hsa-mir-483 Asthma 21305051 "Inverse correlation with the expression of potential mRNA targets identified mmu-miR-146b, -223, -29b, -29c, -483, -574-5p, -672 and -690 as the best candidates for an active implication in asthma pathogenesis. " other hsa-mir-574 Asthma 21305051 "Inverse correlation with the expression of potential mRNA targets identified mmu-miR-146b, -223, -29b, -29c, -483, -574-5p, -672 and -690 as the best candidates for an active implication in asthma pathogenesis. " other hsa-mir-672 Asthma 21305051 "Inverse correlation with the expression of potential mRNA targets identified mmu-miR-146b, -223, -29b, -29c, -483, -574-5p, -672 and -690 as the best candidates for an active implication in asthma pathogenesis. " other hsa-mir-690 Asthma 21305051 "Inverse correlation with the expression of potential mRNA targets identified mmu-miR-146b, -223, -29b, -29c, -483, -574-5p, -672 and -690 as the best candidates for an active implication in asthma pathogenesis. " other hsa-mir-542 Neuroblastoma 21310526 MicroRNA-542-5p as a novel tumor suppressor in neuroblastoma. other hsa-mir-125a Hepatitis B Virus Infection 21317190 "hsa-mir-125a-5p, was found to interact with the viral sequence and to suppress the reporter activity markedly." other hsa-mir-1224 Neoplasms [unspecific] 21320120 Lipopolysaccharide-induced miR-1224 negatively regulates tumour necrosis factor-alpha gene expression by modulating Sp1. other hsa-mir-451a "Carcinoma, Lung, Non-Small-Cell" 21329503 Upregulation of microRNA-451 increases cisplatin sensitivity of non-small cell lung cancer cell line (A549). other hsa-mir-205 "Carcinoma, Renal Cell" 21330408 MicroRNA-205 inhibits Src-mediated oncogenic pathways in renal cancer. other hsa-mir-16-1 "Carcinoma, Hepatocellular" 21336967 P-glycoprotein enhances radiation-induced apoptotic cell death through the regulation of miR-16 and Bcl-2 expressions in hepatocellular carcinoma cells. other hsa-mir-16-2 "Carcinoma, Hepatocellular" 21336967 P-glycoprotein enhances radiation-induced apoptotic cell death through the regulation of miR-16 and Bcl-2 expressions in hepatocellular carcinoma cells. other hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 21350005 "Elevated miR-21 (HR 2.06, 1.13-3.75), miR-17 (HR 2.00, 1.10-3.61), and miR-155 (HR 2.37, 1.27-4.42) was associated with worse cancer-specific mortality in the Maryland cohort." other hsa-mir-17 "Carcinoma, Lung, Non-Small-Cell" 21350005 "Elevated miR-21 (HR 2.06, 1.13-3.75), miR-17 (HR 2.00, 1.10-3.61), and miR-155 (HR 2.37, 1.27-4.42) was associated with worse cancer-specific mortality in the Maryland cohort." other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 21350005 "Elevated miR-21 (HR 2.06, 1.13-3.75), miR-17 (HR 2.00, 1.10-3.61), and miR-155 (HR 2.37, 1.27-4.42) was associated with worse cancer-specific mortality in the Maryland cohort." other hsa-mir-200b Diabetic Retinopathy 21357793 MicroRNA-200b Regulates Vascular Endothelial Growth Factor-Mediated Alterations in Diabetic Retinopathy. other hsa-mir-29b-1 Breast Neoplasms 21359530 miR-29b regulates migration of human breast cancer cells. other hsa-mir-29b-2 Breast Neoplasms 21359530 miR-29b regulates migration of human breast cancer cells. other hsa-mir-145 Prostate Neoplasms 21360565 "SWAP70, actin-binding protein, function as an oncogene targeting tumor-suppressive miR-145 in prostate cancer." other hsa-mir-144 "Tuberculosis, Pulmonary" 21367459 Modulation of T cell cytokine production by miR-144* with elevated expression in patients with pulmonary tuberculosis. other hsa-mir-203 Prostate Neoplasms 21368580 "MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines." other hsa-let-7a-1 Breast Neoplasms 21368581 Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFbeta-induced oncomiR miRNA-181a. other hsa-let-7a-2 Breast Neoplasms 21368581 Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFbe-induced oncomiR miRNA-181a. other hsa-let-7a-3 Breast Neoplasms 21368581 Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFbeta-induced oncomiR miRNA-181a. other hsa-mir-181a-2 Breast Neoplasms 21368581 Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFbeta-induced oncomiR miRNA-181a. other hsa-mir-205 Prostate Neoplasms 21368878 Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells. other hsa-mir-31 Prostate Neoplasms 21368878 Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells. other hsa-mir-1 Inflammation 21385380 "Acute noxious stimulation with capsaicin also increased the expression of miR-1 and -16 in DRG cells but, on the other hand, in the spinal dorsal horn only a high dose of capsaicin was able to downregulate miR-206 expression." other hsa-mir-16 Inflammation 21385380 "Acute noxious stimulation with capsaicin also increased the expression of miR-1 and -16 in DRG cells but, on the other hand, in the spinal dorsal horn only a high dose of capsaicin was able to downregulate miR-206 expression." other hsa-mir-206 Inflammation 21385380 "Acute noxious stimulation with capsaicin also increased the expression of miR-1 and -16 in DRG cells but, on the other hand, in the spinal dorsal horn only a high dose of capsaicin was able to downregulate miR-206 expression." other hsa-mir-210 Preeclampsia 21388516 Elevated levels of hypoxia-inducible microRNA-210 in preeclampsia. other hsa-mir-301a Breast Neoplasms 21393507 miR-301 as a crucial oncogene in human breast cancer that acts through multiple pathways and mechanisms to promote nodal or distant relapses. other hsa-mir-301b Breast Neoplasms 21393507 miR-301 as a crucial oncogene in human breast cancer that acts through multiple pathways and mechanisms to promote nodal or distant relapses. other hsa-mir-125b-1 Colorectal Carcinoma 21399871 miR-125b is directly involved in cancer progression and is associated with poor prognosis in human colorectal cancer. Our findings suggest that miR-125b could be an important prognostic indicator for colorectal cancer patients. other hsa-mir-125b-2 Colorectal Carcinoma 21399871 miR-125b is directly involved in cancer progression and is associated with poor prognosis in human colorectal cancer. Our findings suggest that miR-125b could be an important prognostic indicator for colorectal cancer patients. other hsa-mir-34a Breast Neoplasms 21399894 increased expression of miR-34a in an acquired model of docetaxel resistance in breast cancer. other hsa-mir-223 Multiple Myeloma 21401705 Expression of CD19 and lack of miR-223 distinguish extramedullary plasmacytoma from multiple myeloma. other hsa-mir-31 Breast Neoplasms 21406558 Activation of miR-31 function in already-established metastases elicits metastatic regression. other hsa-mir-16-1 Colorectal Carcinoma 21406606 "Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways." other hsa-mir-16-2 Colorectal Carcinoma 21406606 "Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways." other hsa-mir-19b-1 Colorectal Carcinoma 21406606 "Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways." other hsa-mir-19b-2 Colorectal Carcinoma 21406606 "Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways." other hsa-mir-203 Colorectal Carcinoma 21406606 "Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways." other hsa-mir-21 Colorectal Carcinoma 21406606 "Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways." other hsa-mir-26b Colorectal Carcinoma 21406606 "Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways." other hsa-mir-27b Colorectal Carcinoma 21406606 "Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways." other hsa-mir-93 Colorectal Carcinoma 21406606 "Diet and carcinogen exposure modulated a number of microRNAs (miR-16, miR-19b, miR-21, miR26b, miR27b, miR-93 and miR-203) linked to canonical oncogenic signaling pathways." other hsa-mir-200a Pancreatic Neoplasms 21408027 "Anti-Tumor Activity of a Novel Compound-CDF Is Mediated by Regulating miR-21, miR-200, and PTEN in Pancreatic Cancer." other hsa-mir-200b Pancreatic Neoplasms 21408027 in gemcitabine-resistant (MIAPaCa-2) PC cells containing high proportion of CSCs consistent with increased miR-21 and decreased miR-200. other hsa-mir-200c Pancreatic Neoplasms 21408027 in gemcitabine-resistant (MIAPaCa-2) PC cells containing high proportion of CSCs consistent with increased miR-21 and decreased miR-200. other hsa-mir-21 Pancreatic Neoplasms 21408027 "Anti-Tumor Activity of a Novel Compound-CDF Is Mediated by Regulating miR-21, miR-200, and PTEN in Pancreatic Cancer." other hsa-let-7c Breast Neoplasms 21409395 "let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells" other hsa-let-7b Liposarcoma 21412931 Let-7 MicroRNA and HMGA2 levels of expression are not inversely linked in adipocytic tumors: Analysis of 56 lipomas and liposarcomas with molecular cytogenetic data. other hsa-let-7g Liposarcoma 21412931 Let-7 MicroRNA and HMGA2 levels of expression are not inversely linked in adipocytic tumors: Analysis of 56 lipomas and liposarcomas with molecular cytogenetic data. other hsa-mir-146a Lymphoma 21416002 "In addition, LMP1 can also modulate cellular gene expression programs by affecting, via the NF-¦ÊB pathway, levels of cellular microRNAs miR-146a and miR-155" other hsa-mir-155 Lymphoma 21416002 "In addition, LMP1 can also modulate cellular gene expression programs by affecting, via the NF-¦ÊB pathway, levels of cellular microRNAs miR-146a and miR-155" other hsa-mir-193a Esophageal Neoplasms 21420070 The expression of three miRNAs (miR-99b and miR-199a_3p and _5p) was associated with the presence of lymph node metastasis. other hsa-mir-99b Esophageal Neoplasms 21420070 The expression of three miRNAs (miR-99b and miR-199a_3p and _5p) was associated with the presence of lymph node metastasis. other hsa-mir-34a Ovarian Neoplasms 21423204 We propose that elevated TRP53 and miR-34a-c may exert negatively regulatory effects that reduce the proliferative potential of OSE cells leading to the low-grade serous adenocarcinoma phenotype. other hsa-mir-21 "Squamous Cell Carcinoma, Tongue" 21426775 Anti-sense miRNA-21 oligonucleotide inhibits Tb 3.1 human tongue squamous cell carcinoma growth in vitro.] other hsa-mir-143 Osteosarcoma 21427707 MicroRNA-143 Regulates Human Osteosarcoma Metastasis by Regulating Matrix Metalloprotease-13 Expression. other hsa-mir-101-1 Prostate Neoplasms 21430074 Enforced Expression of miR-101 inhibits prostate cancer cell growth by modulating cyclooxygenase-2 pathway in vivo. other hsa-mir-101-2 Prostate Neoplasms 21430074 Enforced Expression of miR-101 inhibits prostate cancer cell growth by modulating cyclooxygenase-2 pathway in vivo. other hsa-mir-200c Prostate Neoplasms 21431706 Differentially expressed between androgen-dependent and androgen-independent metastatic prostate cancer cells other hsa-mir-205 Prostate Neoplasms 21431706 Differentially expressed between androgen-dependent and androgen-independent metastatic prostate cancer cells other hsa-mir-211 Melanoma 21435193 Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor. other hsa-mir-381 Glioblastoma 21435336 Interaction of hsa-miR-381 and glioma suppressor LRRC4 is involved in glioma growth. other hsa-let-7a Human Papilloma Virus Infection 21442230 "HPV-38 was predicted to express an miRNA conserved to human let-7a and the expression of let-7a, in HPV-38-positive non-melanoma skin cancer (NMSC) biopsies was 10-fold higher than those with HPV-positive (for other types except HPV-38) and HPV-negative NMSCs, suggesting that let-7a expression might be related to HPV-38 infection." other hsa-mir-328 "Carcinoma, Lung, Non-Small-Cell" 21448905 MicroRNA-328 is associated with (non-small) cell lung cancer (NSCLC) brain metastasis and mediates NSCLC migration. other hsa-mir-10 "Leukemia, Myeloid" 21455993 Our analysis identified a strong positive correlation between HOX-related genes and miR-10 and miR-20a. other hsa-mir-128a Leukemia 21455993 "we observed a negative correlation between miR-181a and miR-181b, miR-155, and miR-146 expression with that of genes involved in immunity and inflammation (eg, IRF7 and TLR4) and a positive correlation between miR-23a, miR-26a, miR-128a, and miR-145 expression with that of proapoptotic genes (eg, BIM and PTEN)" other hsa-mir-145 Leukemia 21455993 "we observed a negative correlation between miR-181a and miR-181b, miR-155, and miR-146 expression with that of genes involved in immunity and inflammation (eg, IRF7 and TLR4) and a positive correlation between miR-23a, miR-26a, miR-128a, and miR-145 expression with that of proapoptotic genes (eg, BIM and PTEN)" other hsa-mir-146 Leukemia 21455993 "we observed a negative correlation between miR-181a and miR-181b, miR-155, and miR-146 expression with that of genes involved in immunity and inflammation (eg, IRF7 and TLR4) and a positive correlation between miR-23a, miR-26a, miR-128a, and miR-145 expression with that of proapoptotic genes (eg, BIM and PTEN)" other hsa-mir-155 Leukemia 21455993 "we observed a negative correlation between miR-181a and miR-181b, miR-155, and miR-146 expression with that of genes involved in immunity and inflammation (eg, IRF7 and TLR4) and a positive correlation between miR-23a, miR-26a, miR-128a, and miR-145 expression with that of proapoptotic genes (eg, BIM and PTEN)" other hsa-mir-181a Leukemia 21455993 "we observed a negative correlation between miR-181a and miR-181b, miR-155, and miR-146 expression with that of genes involved in immunity and inflammation (eg, IRF7 and TLR4) and a positive correlation between miR-23a, miR-26a, miR-128a, and miR-145 expression with that of proapoptotic genes (eg, BIM and PTEN)" other hsa-mir-181b Leukemia 21455993 "we observed a negative correlation between miR-181a and miR-181b, miR-155, and miR-146 expression with that of genes involved in immunity and inflammation (eg, IRF7 and TLR4) and a positive correlation between miR-23a, miR-26a, miR-128a, and miR-145 expression with that of proapoptotic genes (eg, BIM and PTEN)" other hsa-mir-20a "Leukemia, Myeloid" 21455993 Our analysis identified a strong positive correlation between HOX-related genes and miR-10 and miR-20a. other hsa-mir-23a Leukemia 21455993 "we observed a negative correlation between miR-181a and miR-181b, miR-155, and miR-146 expression with that of genes involved in immunity and inflammation (eg, IRF7 and TLR4) and a positive correlation between miR-23a, miR-26a, miR-128a, and miR-145 expression with that of proapoptotic genes (eg, BIM and PTEN)" other hsa-mir-26a Leukemia 21455993 "we observed a negative correlation between miR-181a and miR-181b, miR-155, and miR-146 expression with that of genes involved in immunity and inflammation (eg, IRF7 and TLR4) and a positive correlation between miR-23a, miR-26a, miR-128a, and miR-145 expression with that of proapoptotic genes (eg, BIM and PTEN)" other hsa-mir-155 Breast Neoplasms 21460854 miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT. other hsa-mir-1 "Cardiomyopathy, Hypertrophic" 21464712 "The cardiac-enriched miRNAs, including miR-1, miR-133, and miR-208, as well as the ubiquitous miR-23a and miR-199b, play major roles in the development of cardiac hypertrophy." other hsa-mir-133 "Cardiomyopathy, Hypertrophic" 21464712 "The cardiac-enriched miRNAs, including miR-1, miR-133, and miR-208, as well as the ubiquitous miR-23a and miR-199b, play major roles in the development of cardiac hypertrophy." other hsa-mir-199a Ischemic Diseases [unspecific] 21464712 "On the other hand, miR-21, miR-199a, miR-210, and miR-494 have been proven critical for the myocytes' adaptation and survival during hypoxia/ischemia." other hsa-mir-199b "Cardiomyopathy, Hypertrophic" 21464712 "The cardiac-enriched miRNAs, including miR-1, miR-133, and miR-208, as well as the ubiquitous miR-23a and miR-199b, play major roles in the development of cardiac hypertrophy." other hsa-mir-208 "Cardiomyopathy, Hypertrophic" 21464712 "The cardiac-enriched miRNAs, including miR-1, miR-133, and miR-208, as well as the ubiquitous miR-23a and miR-199b, play major roles in the development of cardiac hypertrophy." other hsa-mir-21 Ischemic Diseases [unspecific] 21464712 "On the other hand, miR-21, miR-199a, miR-210, and miR-494 have been proven critical for the myocytes' adaptation and survival during hypoxia/ischemia." other hsa-mir-210 Ischemic Diseases [unspecific] 21464712 "On the other hand, miR-21, miR-199a, miR-210, and miR-494 have been proven critical for the myocytes' adaptation and survival during hypoxia/ischemia." other hsa-mir-23a "Cardiomyopathy, Hypertrophic" 21464712 "The cardiac-enriched miRNAs, including miR-1, miR-133, and miR-208, as well as the ubiquitous miR-23a and miR-199b, play major roles in the development of cardiac hypertrophy." other hsa-mir-494 Ischemic Diseases [unspecific] 21464712 "On the other hand, miR-21, miR-199a, miR-210, and miR-494 have been proven critical for the myocytes' adaptation and survival during hypoxia/ischemia." other hsa-mir-210 Inflammation 21467158 miRNA-210 is a good example in this category that impairs wound closure. other hsa-mir-21 Urinary Bladder Cancer 21468550 microRNA-21 modulates cell proliferation and sensitivity to doxorubicin in bladder cancer cells other hsa-mir-21 Breast Neoplasms 21471222 Upregulation of MIR-21 mediates resistance to trastuzumab therapy for breast cancer. other hsa-mir-10b Glioblastoma 21471404 Human glioma growth is controlled by microRNA-10b other hsa-mir-146a "Carcinoma, Renal Cell" 21472233 "Carbamylated albumin stimulates microRNA-146, which is increased in human renal cell carcinoma." other hsa-mir-146b "Carcinoma, Renal Cell" 21472233 "Carbamylated albumin stimulates microRNA-146, which is increased in human renal cell carcinoma." other hsa-let-7g Lung Neoplasms 21472347 Precursor let-7g microRNA can supress A549 lung cancer cell migration. other hsa-mir-146a Breast Neoplasms 21472990 Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. other hsa-mir-146b Breast Neoplasms 21472990 Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. other hsa-mir-517a Urinary Bladder Cancer 21479368 Restoration of miR-517a expression induces cell apoptosis in bladder cancer cell lines. other hsa-mir-221 Neoplasms [unspecific] 21481725 miRNA-221/-222 control radiation sensitivity by regulating the PTEN/AKT pathway and can be explored as novel targets for radiosensitization. other hsa-mir-222 Neoplasms [unspecific] 21481725 miRNA-221/-222 control radiation sensitivity by regulating the PTEN/AKT pathway and can be explored as novel targets for radiosensitization. other hsa-mir-503 "Carcinoma, Hepatocellular" 21495032 microRNA-503 regulates metastatic function in hepatocellular cancer cell. other hsa-mir-22 Neoplasms [unspecific] 21502362 miR-22 represses cancer progression by inducing cellular senescence. other hsa-mir-150 Lymphoma 21502955 microRNA-150 is a tumor suppressor in malignant lymphoma other hsa-mir-183 Lung Neoplasms 21503569 microRNA-182 inhibits the proliferation and invasion of human lung adenocarcinoma cells through its effect on human cortical actin-associated protein. other hsa-mir-192 Retinoblastoma 21511813 MicroRNA-192 targeting retinoblastoma 1 inhibits cell proliferation and induces cell apoptosis in lung cancer cells. other hsa-mir-193b Breast Neoplasms 21512034 "we present here a proteomic screen to identify targets of miR-193b, and a systems biological approach to mimic its effects at the level of cellular phenotypes." other hsa-mir-1-1 Hepatitis B Virus Infection 21520166 "MiR-1 regulates the expression of several host genes to enhance HBV replication and reverse cancer cell phenotype, which is apparently beneficial for HBV replication." other hsa-mir-1-2 Hepatitis B Virus Infection 21520166 "MiR-1 regulates the expression of several host genes to enhance HBV replication and reverse cancer cell phenotype, which is apparently beneficial for HBV replication." other hsa-mir-181a Lymphoma 21525173 "A multivariate Cox regression analysis including the IPI, the 6-gene model-derived mortality predictor score and expression of the miR-18a, miR-181a, and miR-222, revealed that all variables were independent predictors of survival except the expression of miR-222 for OS and the expression of miR-18a for PFS." other hsa-mir-18a Lymphoma 21525173 "A multivariate Cox regression analysis including the IPI, the 6-gene model-derived mortality predictor score and expression of the miR-18a, miR-181a, and miR-222, revealed that all variables were independent predictors of survival except the expression of miR-222 for OS and the expression of miR-18a for PFS." other hsa-mir-222 Lymphoma 21525173 "A multivariate Cox regression analysis including the IPI, the 6-gene model-derived mortality predictor score and expression of the miR-18a, miR-181a, and miR-222, revealed that all variables were independent predictors of survival except the expression of miR-222 for OS and the expression of miR-18a for PFS." other hsa-mir-15a Multiple Myeloma 21534877 Bone marrow stromal cells protect myeloma cells from bortezomib induced apoptosis by suppressing microRNA-15a expression. other hsa-mir-16-1 Prostate Neoplasms 21539977 "We observed correlations with clinical-pathologic parameters: miR-16, miR-195, and miR-26a were significantly correlated with surgical margin positivity; miR-195 and miR-let7i were significantly correlated with the Gleason score." other hsa-mir-16-2 Prostate Neoplasms 21539977 "We observed correlations with clinical-pathologic parameters: miR-16, miR-195, and miR-26a were significantly correlated with surgical margin positivity; miR-195 and miR-let7i were significantly correlated with the Gleason score." other hsa-mir-195 Prostate Neoplasms 21539977 "We observed correlations with clinical-pathologic parameters: miR-16, miR-195, and miR-26a were significantly correlated with surgical margin positivity; miR-195 and miR-let7i were significantly correlated with the Gleason score." other hsa-mir-26a-1 Prostate Neoplasms 21539977 "We observed correlations with clinical-pathologic parameters: miR-16, miR-195, and miR-26a were significantly correlated with surgical margin positivity; miR-195 and miR-let7i were significantly correlated with the Gleason score." other hsa-mir-26a-2 Prostate Neoplasms 21539977 "We observed correlations with clinical-pathologic parameters: miR-16, miR-195, and miR-26a were significantly correlated with surgical margin positivity; miR-195 and miR-let7i were significantly correlated with the Gleason score." other hsa-mir-155 Nasopharyngeal Neoplasms 21541331 Upregulation of MiR-155 in Nasopharyngeal Carcinoma is Partly Driven by LMP1 and LMP2A and Downregulates a Negative Prognostic Marker JMJD1A. other hsa-mir-34a Melanoma 21541354 miR-34a and miR-185 were further shown to inhibit the growth of melanoma xenografts when implanted in SCID-NOD mice. other hsa-mir-142 Melanoma 21543894 "miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04)." other hsa-mir-214 Melanoma 21543894 "miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04)." other hsa-mir-218-1 Melanoma 21543894 "miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04)." other hsa-mir-218-2 Melanoma 21543894 "miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04)." other hsa-mir-31 Melanoma 21543894 "miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04)." other hsa-mir-362 Melanoma 21543894 "miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04)." other hsa-mir-486 Melanoma 21543894 "miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04)." other hsa-mir-650 Melanoma 21543894 "miR-142-3p, miR-486, miR-214, miR-218, miR-362, miR-650 and miR-31, were significantly correlated with acral as compared to non-acral melanomas (p < 0.04)." other hsa-let-7d Prostate Neoplasms 21548940 PBX3 is up-regulated in prostate cancer and post- transcriptionally regulated by androgen through Let-7d. other hsa-mir-143 Urinary Bladder Cancer 21550168 MicroRNA-143 functions as a tumor suppressor in human bladder cancer T24 cells other hsa-mir-135a-1 "Carcinoma, Lung, Non-Small-Cell" 21552288 miR-135a contributes to paclitaxel resistance in tumor cells both in vitro and in vivo. other hsa-mir-135a-2 "Carcinoma, Lung, Non-Small-Cell" 21552288 miR-135a contributes to paclitaxel resistance in tumor cells both in vitro and in vivo. other hsa-mir-200c Breast Neoplasms 21553120 "Suppression of miR-200c, miR-203, and miR-205 and increases in miR-222 and miR-221 are involved in the inducement of EMT and repression of the estrogen receptor." other hsa-mir-203 Breast Neoplasms 21553120 "Suppression of miR-200c, miR-203, and miR-205 and increases in miR-222 and miR-221 are involved in the inducement of EMT and repression of the estrogen receptor." other hsa-mir-205 Breast Neoplasms 21553120 "Suppression of miR-200c, miR-203, and miR-205 and increases in miR-222 and miR-221 are involved in the inducement of EMT and repression of the estrogen receptor." other hsa-mir-221 Breast Neoplasms 21553120 "Suppression of miR-200c, miR-203, and miR-205 and increases in miR-222 and miR-221 are involved in the inducement of EMT and repression of the estrogen receptor." other hsa-mir-222 Breast Neoplasms 21553120 "Suppression of miR-200c, miR-203, and miR-205 and increases in miR-222 and miR-221 are involved in the inducement of EMT and repression of the estrogen receptor." other hsa-mir-146a Neoplasms [unspecific] 21555486 "miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice." other hsa-mir-143 Rectal Neoplasms 21567082 Altered levels of the onco-microRNA 21 and the tumor-supressor microRNAs 143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapy. other hsa-mir-145 Rectal Neoplasms 21567082 Altered levels of the onco-microRNA 21 and the tumor-supressor microRNAs 143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapy. other hsa-mir-21 Rectal Neoplasms 21567082 Altered levels of the onco-microRNA 21 and the tumor-supressor microRNAs 143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapy. other hsa-mir-27a Gastric Neoplasms 21569481 Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells. other hsa-mir-92a-1 Neuroblastoma 21572098 MYCN-regulated miRNA-92 Inhibits Secretion of the Tumor Suppressor DICKKOPF-3 (DKK3) in Neuroblastoma. other hsa-mir-92a-2 Neuroblastoma 21572098 MYCN-regulated miRNA-92 Inhibits Secretion of the Tumor Suppressor DICKKOPF-3 (DKK3) in Neuroblastoma. other hsa-mir-92b Neuroblastoma 21572098 MYCN-regulated miRNA-92 Inhibits Secretion of the Tumor Suppressor DICKKOPF-3 (DKK3) in Neuroblastoma. other hsa-mir-15a "Carcinoma, Lung, Non-Small-Cell" 21575235 miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. other hsa-mir-16-1 "Carcinoma, Lung, Non-Small-Cell" 21575235 miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. other hsa-mir-16-2 "Carcinoma, Lung, Non-Small-Cell" 21575235 miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. other hsa-mir-34a "Carcinoma, Lung, Non-Small-Cell" 21575235 miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. other hsa-mir-133a "Cardiomyopathy, Hypertrophic" 21586423 "Logistic regression analysis identified microRNA-133a as a significant positive predictor of LVM normalisation, whereas ¦Â-myosin heavy chain and BMI constituted negative predictors." other hsa-mir-146a Ovarian Neoplasms 21591024 "In conclusion, the polymorphism in the miR-146a gene is unlikely to be of substantial significance regarding breast cancer risk." other hsa-mir-335 Astrocytoma 21592405 Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells. other hsa-mir-7-1 Neoplasms [unspecific] 21592959 USP18 regulates EGF receptor expression and cancer cell survival via microrna-7. other hsa-mir-7-2 Neoplasms [unspecific] 21592959 USP18 regulates EGF receptor expression and cancer cell survival via microrna-7. other hsa-mir-7-3 Neoplasms [unspecific] 21592959 USP18 regulates EGF receptor expression and cancer cell survival via microrna-7. other hsa-mir-214 Melanoma 21593728 miR-214 drives melanoma metastasis. other hsa-mir-29a Hepatitis C Virus Infection 21606534 Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture. other hsa-mir-29b-1 Hepatitis C Virus Infection 21606534 Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture. other hsa-mir-29b-2 Hepatitis C Virus Infection 21606534 Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture. other hsa-mir-29c Hepatitis C Virus Infection 21606534 Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture. other hsa-mir-26a-1 "Carcinoma, Hepatocellular" 21610700 Tumor-specific Expression of MicroRNA-26a Suppresses Human Hepatocellular Carcinoma Growth via Cyclin-dependent and -independent Pathways. other hsa-mir-26a-2 "Carcinoma, Hepatocellular" 21610700 Tumor-specific Expression of MicroRNA-26a Suppresses Human Hepatocellular Carcinoma Growth via Cyclin-dependent and -independent Pathways. other hsa-mir-346 Rheumatoid Arthritis 21611196 miR-346 Controls Release of TNF-a Protein and Stability of Its mRNA in Rheumatoid Arthritis via Tristetraprolin Stabilization. other hsa-mir-21 Diabetes Mellitus 21613227 microRNA-21 orchestrates high glucose-induced signals to TORC1 for renal cell pathology in diabetes. other hsa-mir-21 Glioblastoma 21618027 A miR-21 inhibitor enhances apoptosis and reduces G(2)-M accumulation induced by ionizing radiation in human glioblastoma U251 cells. other hsa-let-7 Ovarian Neoplasms 21618519 Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1. other hsa-mir-183 Congenital Deafness 21621863 The quantitative real-time polymerase chain reaction result demonstrated that the miR-183 family exhibits cell-specific expression in cochlear progenitor cells compared with neural stem cells. other hsa-mir-34a Pancreatic Neoplasms 21622730 "Two miRNA candidates known to be downregulated in the majority of pancreatic cancers were selected for nanovector delivery: miR-34a, which is a component of the p53 transcriptional network and regulates cancer stem cell survival, and the miR-143/145 cluster, which together repress the expression of KRAS2 and its downstream effector Ras-responsive element binding protein-1 (RREB1)." other hsa-mir-22 Colorectal Carcinoma 21629773 MicroRNA-22 regulates hypoxia signaling in colon cancer cells. other hsa-mir-1246 Down Syndrome 21637297 p53 downregulates Down syndrome-associated DYRK1A through miR-1246. other hsa-mir-130a "Leukemia, Myeloid" 21638198 MicroRNAs 130a/b are regulated by BCR-ABL and downregulate expression of CCN3 in CML (Chronic Myeloid Leukaemia). other hsa-mir-130b "Leukemia, Myeloid" 21638198 MicroRNAs 130a/b are regulated by BCR-ABL and downregulate expression of CCN3 in CML (Chronic Myeloid Leukaemia). other hsa-mir-21 Wounds and Injuries [unspecific] 21647251 miR-21 promotes keratinocyte migration and re-epithelialization during wound healing. other hsa-mir-143 Prostate Neoplasms 21647377 miRs-143 and -145 are associated with bone metastasis of prostate cancer and involved in the regulation of EMT. other hsa-mir-145 Prostate Neoplasms 21647377 miRs-143 and -145 are associated with bone metastasis of prostate cancer and involved in the regulation of EMT. other hsa-mir-10b Pancreatic Neoplasms 21652542 microRNA-10b Expression Correlates with Response to Neoadjuvant Therapy and Survival in Pancreatic Ductal Adenocarcinoma. other hsa-mir-122 Hepatitis C Virus Infection 21653556 miR-122 activates hepatitis C virus translation by a specialized mechanism requiring particular RNA components. other hsa-mir-143 Colon Neoplasms 21653642 "EGFR suppresses miR-143 and miR-145 in murine models of colon cancer. Furthermore, Western diet unmasks the tumor suppressor roles of these EGFR-regulated miRNAs." other hsa-mir-145 Colon Neoplasms 21653642 "EGFR suppresses miR-143 and miR-145 in murine models of colon cancer. Furthermore, Western diet unmasks the tumor suppressor roles of these EGFR-regulated miRNAs." other hsa-mir-103a-1 "Diabetes Mellitus, Type 2" 21654750 MicroRNAs 103 and 107 regulate insulin sensitivity. other hsa-mir-103a-2 "Diabetes Mellitus, Type 2" 21654750 MicroRNAs 103 and 107 regulate insulin sensitivity. other hsa-mir-17 Multiple Myeloma 21664042 miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. other hsa-mir-18a Multiple Myeloma 21664042 miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. other hsa-mir-19a Multiple Myeloma 21664042 miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. other hsa-mir-19b-1 Multiple Myeloma 21664042 miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. other hsa-mir-20a Multiple Myeloma 21664042 miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. other hsa-mir-92a-1 Multiple Myeloma 21664042 miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. other hsa-mir-483 Wounds and Injuries [unspecific] 21676945 miR-483-3p controls proliferation in wounded epithelial cells. other hsa-mir-429 Gastric Neoplasms 21684154 miR-429 Modulates the expression of c-myc in human gastric carcinoma cells. other hsa-mir-21 "Squamous Cell Carcinoma, Head and Neck" 21685938 Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells. other hsa-mir-143 Liposarcoma 21693658 microRNA-143 is a tumor suppressor activity in liposarcoma other hsa-mir-34a Urinary Bladder Cancer 21702042 MiR-34a chemo-sensitizes bladder cancer cells to cisplatin treatment regardless of P53-Rb pathway status. other hsa-mir-125b-1 "Carcinoma, Hepatocellular" 21703189 microRNA-125b regulates of placenta growth factor in hepatocellular cancer other hsa-mir-125b-2 "Carcinoma, Hepatocellular" 21703189 microRNA-125b regulates of placenta growth factor in hepatocellular cancer other hsa-mir-519d Prostate Neoplasms 21703393 "miR-519d,and miR-647 could be used to separate patients with and without biochemical recurrence" other hsa-mir-647 Prostate Neoplasms 21703393 "miR-519d,and miR-647 could be used to separate patients with and without biochemical recurrence" other hsa-mir-378a Myelodysplastic Syndromes 21703983 "hsa-mir-378, hsa-miR-632, and hsa-miR-636 demonstrated particularly high discrimination between MDS and normal controls." other hsa-mir-632 Myelodysplastic Syndromes 21703983 "hsa-mir-378, hsa-miR-632, and hsa-miR-636 demonstrated particularly high discrimination between MDS and normal controls." other hsa-mir-636 Myelodysplastic Syndromes 21703983 "hsa-mir-378, hsa-miR-632, and hsa-miR-636 demonstrated particularly high discrimination between MDS and normal controls." other hsa-mir-130a "Carcinoma, Hepatocellular" 21712254 The hepatitis B virus-associated estrogen receptor alpha (ER{alpha}) was regulated by microRNA-130a in HepG2.2.15 human hepatocellular carcinoma cells. other hsa-mir-21 Cardiovascular Diseases [unspecific] 21712654 "The small regulatory RNA microRNA-21 (miR-21) plays a crucial role in a plethora of biological functions and diseases including development, cancer, cardiovascular diseases and inflammation." other hsa-mir-21 Multiple Myeloma 21718132 Myeloma cell adhesion to bone marrow stromal cells confers drug resistance by microRNA-21 up-regulation. other hsa-let-7b Colorectal Carcinoma 21722265 The miRNA has a role in colorectal liver metastases. other hsa-mir-1275 Colorectal Carcinoma 21722265 The miRNA has a role in colorectal liver metastases. other hsa-mir-143 Colorectal Carcinoma 21722265 The miRNA has a role in colorectal liver metastases. other hsa-mir-145 Colorectal Carcinoma 21722265 The miRNA has a role in colorectal liver metastases. other hsa-mir-194-1 Colorectal Carcinoma 21722265 The miRNA has a role in colorectal liver metastases. other hsa-mir-194-2 Colorectal Carcinoma 21722265 The miRNA has a role in colorectal liver metastases. other hsa-mir-19b-1 Colorectal Carcinoma 21722265 The miRNA has a role in colorectal liver metastases. other hsa-mir-19b-2 Colorectal Carcinoma 21722265 The miRNA has a role in colorectal liver metastases. other hsa-mir-638 Colorectal Carcinoma 21722265 The miRNA has a role in colorectal liver metastases. other hsa-mir-375 Melanoma 21723283 "Ectopic expression of miR-375 inhibited melanoma cell proliferation, invasion, and cell motility, and induced cell shape changes, strongly suggesting that miR-375 may have an important function in the development and progression of human melanomas." other hsa-mir-141 Prostate Neoplasms 21723797 miR-141 demonstrated high correlation with changes of the other biomarkers. other hsa-let-7d "Squamous Cell Carcinoma, Oral" 21725603 Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer. other hsa-mir-141 Choriocarcinoma 21726338 Reduction in miR-141 is induced by leukemia inhibitory factor and inhibits proliferation in choriocarcinoma cell line JEG-3. other hsa-mir-125b "Leukemia-Lymphoma, Precursor B-Cell Lymphoblastic" 21738213 Our results provide direct evidence that miR-125b has important roles in the tumorigenesis of precursor B cells. other hsa-mir-210 Breast Neoplasms 21738599 "MiR-210 associated with tumor proliferation, invasion and poor clinical outcome in breast cancer." other hsa-let-7i Immune System Disease [unspecific] 21742974 Dynamic regulation of let-7i may fine-tune immune responses by inducing Ag-specific immune tolerance. other hsa-mir-1286 Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-199a-1 Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-199a-2 Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-302a Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-302f Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-342 Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-425 Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-455 Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-486 Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-519c Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-548d-1 Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-548d-2 Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-617 Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-758 Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-766 Esophageal Neoplasms 21743970 "Thirteen miRNAs (miR-199a-5p, miR-302f, miR-320a, miR-342-3p, miR-425, miR-455-3p, miR-486-3p, miR-519c-5p, miR-548d-5p, miR-617, miR-758, miR-766, miR-1286) were deregulated after 24- and/or 72-h treatment by Chemotherapy." other hsa-mir-22 "Carcinoma, Hepatocellular" 21750200 miR-22 promotes HBV related hepatocellular carcinoma development in males. other hsa-mir-103a-1 Hypertension 21753805 MicroRNA-130a Mediates Proliferation of Vascular Smooth Muscle Cells in Hypertension. other hsa-mir-103a-2 Hypertension 21753805 MicroRNA-130a Mediates Proliferation of Vascular Smooth Muscle Cells in Hypertension. other hsa-mir-18a Breast Neoplasms 21755340 "miR-18a expression was much higher in ERa-negative than in ERa-positive tumors (P < 0.0001), with the expression levels of miR-18a not differing in ERa-positive breast cancer as a function of ERa protein level." other hsa-mir-18b Breast Neoplasms 21755340 "Low miR-18b expression was significantly associated with improved survival in HER2-negative breast cancer, although miR-18b expression was not correlated with ERa protein expression." other hsa-mir-193b Breast Neoplasms 21755340 "The expression levels of miR-193b and miR-221 were significantly lower in ERa-negative than in ERa-positive tumors (P = 0.0015 and P = 0.0045, respectively), and the levels of these miRNAs gradually increased as ERa protein expression increased." other hsa-mir-221 Breast Neoplasms 21755340 "The expression levels of miR-193b and miR-221 were significantly lower in ERa-negative than in ERa-positive tumors (P = 0.0015 and P = 0.0045, respectively), and the levels of these miRNAs gradually increased as ERa protein expression increased." other hsa-mir-542 Neoplasms [unspecific] 21756784 "miR-542-3p affects carcinogenesis induced by anti-benzo(a) pyrene-7,8-diol-9,10-epoxide" other hsa-mir-130b Multiple Myeloma 21761344 "miR-130b, miR-181a, and miR-636 to be differentially expressed between GC-sensitive and GC-resistant MM.1 cell lines." other hsa-mir-181a-1 Multiple Myeloma 21761344 "miR-130b, miR-181a, and miR-636 to be differentially expressed between GC-sensitive and GC-resistant MM.1 cell lines." other hsa-mir-181a-2 Multiple Myeloma 21761344 "miR-130b, miR-181a, and miR-636 to be differentially expressed between GC-sensitive and GC-resistant MM.1 cell lines." other hsa-mir-636 Multiple Myeloma 21761344 "miR-130b, miR-181a, and miR-636 to be differentially expressed between GC-sensitive and GC-resistant MM.1 cell lines." other hsa-mir-155 Lung Neoplasms 21762626 "miR-155 could significantly inhibit the growth of human lung cancer 95D cells in vitro, which might be closely related to miR-155 induced G0/G1 phase arrest." other hsa-mir-138-1 "Squamous Cell Carcinoma, Head and Neck" 21770894 MicroRNA-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines. other hsa-mir-138-2 "Squamous Cell Carcinoma, Head and Neck" 21770894 MicroRNA-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines. other hsa-mir-21 Medulloblastoma 21775132 MicroRNA-21 suppression impedes medulloblastoma cell migration. other hsa-mir-221 Pancreatic Neoplasms 21779484 The miRNA is Potentially Associated with Antiproliferative Activity of Benzyl Isothiocyanate in Pancreatic Cancer other hsa-mir-375 Pancreatic Neoplasms 21779484 The miRNA is Potentially Associated with Antiproliferative Activity of Benzyl Isothiocyanate in Pancreatic Cancer other hsa-mir-29a Renal Fibrosis 21784902 TGF-{beta}/Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29. other hsa-mir-29b-1 Renal Fibrosis 21784902 TGF-{beta}/Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29. other hsa-mir-29b-2 Renal Fibrosis 21784902 TGF-{beta}/Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29. other hsa-mir-29c Renal Fibrosis 21784902 TGF-{beta}/Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29. other hsa-mir-203 "Carcinoma, Hepatocellular" 21786180 miR-203 expression predicts outcome after liver transplantation for hepatocellular carcinoma in cirrhotic liver. other hsa-mir-138-1 "Carcinoma, Lung, Non-Small-Cell" 21787234 miR-138 could play an important role in the development of cisplatin resistance in non-small cell lung cancer (NSCLC) other hsa-mir-138-2 "Carcinoma, Lung, Non-Small-Cell" 21787234 miR-138 could play an important role in the development of cisplatin resistance in non-small cell lung cancer (NSCLC) other hsa-mir-205 Breast Neoplasms 21787752 ErbB2 down-regulates microRNA-205 in breast cancer. other hsa-mir-155 Encephalomyelitis 21788439 Silencing MicroRNA-155 Ameliorates Experimental Autoimmune Encephalomyelitis. other hsa-mir-24-1 Myocardial Infarction 21788589 MicroRNA-24 Regulates Vascularity After Myocardial Infarction other hsa-mir-24-2 Myocardial Infarction 21788589 MicroRNA-24 Regulates Vascularity After Myocardial Infarction other hsa-mir-19b-1 Antiphospholipid Syndrome 21794077 Down-regulation of miR-19b and miR-20a observed in patients with SLE and SAF could contribute to increase TF expression and thus provoke the hypercoagulable state characteristic of these patients. other hsa-mir-19b-1 Systemic Lupus Erythematosus 21794077 Down-regulation of miR-19b and miR-20a observed in patients with SLE and SAF could contribute to increase TF expression and thus provoke the hypercoagulable state characteristic of these patients. other hsa-mir-20a Antiphospholipid Syndrome 21794077 Down-regulation of miR-19b and miR-20a observed in patients with SLE and SAF could contribute to increase TF expression and thus provoke the hypercoagulable state characteristic of these patients. other hsa-mir-20a Systemic Lupus Erythematosus 21794077 Down-regulation of miR-19b and miR-20a observed in patients with SLE and SAF could contribute to increase TF expression and thus provoke the hypercoagulable state characteristic of these patients. other hsa-mir-155 Acute Coronary Syndrome 21804579 The altered expression of inflammation-related microRNAs with microRNA-155 expression correlates with Th17 differentiation in patients with acute coronary syndrome. other hsa-mir-155 Colorectal Carcinoma 21806946 "Neurotensin Signaling Activates MicroRNAs -21 and -155 and Akt, Promotes Tumor Growth in Mice, and is Increased in Human Colon Tumors." other hsa-mir-21 Colorectal Carcinoma 21806946 "Neurotensin Signaling Activates MicroRNAs -21 and -155 and Akt, Promotes Tumor Growth in Mice, and is Increased in Human Colon Tumors." other hsa-mir-1-1 Acute Coronary Syndrome 21806992 The miRNA was independently associated with hsTnT levels. other hsa-mir-1-2 Acute Coronary Syndrome 21806992 The miRNA was independently associated with hsTnT levels. other hsa-mir-133a-1 Acute Coronary Syndrome 21806992 The miRNA was independently associated with hsTnT levels. Its level was significantly associated with the risk of death in univariate and age- and gender-adjusted analyses. other hsa-mir-133a-2 Acute Coronary Syndrome 21806992 The miRNA was independently associated with hsTnT levels. Its level was significantly associated with the risk of death in univariate and age- and gender-adjusted analyses. other hsa-mir-133b Acute Coronary Syndrome 21806992 The miRNA was independently associated with hsTnT levels. other hsa-mir-208b Acute Coronary Syndrome 21806992 The miRNA was independently associated with hsTnT levels. Its level was significantly associated with the risk of death in univariate and age- and gender-adjusted analyses. other hsa-mir-637 "Carcinoma, Hepatocellular" 21809363 Primate-specific miRNA-637 inhibits tumorigenesis in hepatocellular carcinoma by disrupting stat3 signaling. other hsa-mir-17 Retinoblastoma 21816922 miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. other hsa-mir-18a Retinoblastoma 21816922 miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. other hsa-mir-19a Retinoblastoma 21816922 miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. other hsa-mir-19b-1 Retinoblastoma 21816922 miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. other hsa-mir-20a Retinoblastoma 21816922 miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. other hsa-mir-92a-1 Retinoblastoma 21816922 miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. other hsa-mir-21 Atherosclerosis 21817107 MicroRNA-21 Regulates Vascular Smooth Muscle Cell Function via Targeting Tropomyosin 1 in Arteriosclerosis Obliterans of Lower Extremities. other hsa-mir-101-1 Ovarian Neoplasms 21818714 MicroRNA-101 Inhibits Growth of Epithelial Ovarian Cancer by Relieving Chromatin-Mediated Transcriptional Repression of p21(waf1/cip1). other hsa-mir-101-2 Ovarian Neoplasms 21818714 MicroRNA-101 Inhibits Growth of Epithelial Ovarian Cancer by Relieving Chromatin-Mediated Transcriptional Repression of p21(waf1/cip1). other hsa-mir-155 Pancreatic Neoplasms 21826251 preferential expression in holoclones other hsa-mir-21 Pancreatic Neoplasms 21826251 preferential expression in holoclones other hsa-mir-214 Pancreatic Neoplasms 21826251 preferential expression in holoclones other hsa-mir-221 Pancreatic Neoplasms 21826251 preferential expression in holoclones other hsa-mir-222 Pancreatic Neoplasms 21826251 preferential expression in holoclones other hsa-mir-155 "Lymphoma, Burkitt" 21831295 miR-93 repressed human activation induced cytidine deaminase. other hsa-mir-93 "Lymphoma, Burkitt" 21831295 miR-93 repressed human activation induced cytidine deaminase. other hsa-mir-203 Urinary Bladder Cancer 21836020 Curcumin modulates microRNA-203 mediated regulation of the Src-Akt axis in bladder cancer. other hsa-mir-15a Leukemia 21838537 These data indicate that miR-15a/16-1 plays an important role in the ATRA-induced differentiation of leukemic and primary AML cells. other hsa-mir-184 "Carcinoma, Renal Cell" 21844955 miR-184 show abnormal expression in human renal carcinoma. other hsa-mir-194-1 Gastric Neoplasms 21845495 There is an inverse Association between miR-194 Expression and Tumor Invasion in Gastric Cancer. other hsa-mir-194-2 Gastric Neoplasms 21845495 There is an inverse Association between miR-194 Expression and Tumor Invasion in Gastric Cancer. other hsa-mir-874 "Squamous Cell Carcinoma, Maxillary Sinus" 21847129 Tumour suppressive microRNA-874 regulates novel cancer networks in maxillary sinus squamous cell carcinoma. other hsa-mir-708 "Carcinoma, Renal Cell" 21852381 MicroRNA-708 induces apoptosis and suppresses tumorigenicity in renal cancer cells. other hsa-mir-21 Renal Fibrosis 21852586 Smad3-Mediated Upregulation of miR-21 Promotes Renal Fibrosis. other hsa-mir-126 Ischemia 21856785 MicroRNA-126 modulates endothelial SDF-1 expression and mobilization of Sca-1+/Lin- progenitor cells in ischemia. other hsa-mir-203 "Leukemia-Lymphoma, Adult T-Cell" 21865341 repressed other hsa-mir-205 "Leukemia-Lymphoma, Adult T-Cell" 21865341 repressed other hsa-mir-326 "Leukemia-Lymphoma, Adult T-Cell" 21865341 induced other hsa-mir-663a "Leukemia-Lymphoma, Adult T-Cell" 21865341 induced other hsa-mir-711 "Leukemia-Lymphoma, Adult T-Cell" 21865341 induced other hsa-mir-15b Influenza 21872652 Ginsenoside metabolite protopanaxatriol showed significant suppression effect on IP-10 production upon H9N2/G1 infection through up-regulation of miR-15b expression. other hsa-mir-200c Colorectal Carcinoma 21873159 Oncogenic KRAS Regulates miR-200c and miR-221/222 in a 3D-Specific Manner in Colorectal Cancer Cells. other hsa-mir-221 Colorectal Carcinoma 21873159 Oncogenic KRAS Regulates miR-200c and miR-221/222 in a 3D-Specific Manner in Colorectal Cancer Cells. other hsa-mir-222 Colorectal Carcinoma 21873159 Oncogenic KRAS Regulates miR-200c and miR-221/222 in a 3D-Specific Manner in Colorectal Cancer Cells. other hsa-mir-149 Nasopharyngeal Neoplasms 21873783 miR-149 promotes epithelial-mesenchymal transition and invasion in nasopharyngeal carcinoma cells. other hsa-mir-128-1 Glioblastoma 21874051 Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases. other hsa-mir-128-2 Glioblastoma 21874051 Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases. other hsa-mir-138-1 "Carcinoma, Renal Cell" 21875287 MiR-138 Suppresses Expression of Hypoxia-inducible factor 1a (HIF-1a) in Clear Cell Renal Cell Carcinoma 786-O Cells. other hsa-mir-138-2 "Carcinoma, Renal Cell" 21875287 MiR-138 Suppresses Expression of Hypoxia-inducible factor 1a (HIF-1a) in Clear Cell Renal Cell Carcinoma 786-O Cells. other hsa-mir-31 Neoplasms [unspecific] 21875932 miR-31 is a master regulator of integrins. The expression of miR-31 in cancer cells resulted in a significant repression of these integrin subunits both at the mRNA and protein levels. other hsa-mir-101-1 "Carcinoma, Hepatocellular" 21876625 potential associated miRNA other hsa-mir-101-1 Hepatitis B Virus Infection 21876625 potential associated miRNA other hsa-mir-101-2 "Carcinoma, Hepatocellular" 21876625 potential associated miRNA other hsa-mir-101-2 Hepatitis B Virus Infection 21876625 potential associated miRNA other hsa-mir-106a "Carcinoma, Hepatocellular" 21876625 potential associated miRNA other hsa-mir-106a Hepatitis B Virus Infection 21876625 potential associated miRNA other hsa-mir-106b "Carcinoma, Hepatocellular" 21876625 potential associated miRNA other hsa-mir-106b Hepatitis B Virus Infection 21876625 potential associated miRNA other hsa-mir-18a "Carcinoma, Hepatocellular" 21876625 potential associated miRNA other hsa-mir-18a Hepatitis B Virus Infection 21876625 potential associated miRNA other hsa-mir-18b "Carcinoma, Hepatocellular" 21876625 potential associated miRNA other hsa-mir-18b Hepatitis B Virus Infection 21876625 potential associated miRNA other hsa-mir-125b-1 "Leukemia, Promyelocytic, Acute" 21880154 Upregulation of microRNA-125b contributes to leukemogenesis and increases drug resistance in pediatric acute promyelocytic leukemia. other hsa-mir-29a "Leukemia, Myeloid, Acute" 21880628 miR-29a and miR-30c might contribute to the sensitivity to cytarabine other hsa-mir-30c-1 "Leukemia, Myeloid, Acute" 21880628 miR-29a and miR-30c might contribute to the sensitivity to cytarabine other hsa-mir-30c-2 "Leukemia, Myeloid, Acute" 21880628 miR-29a and miR-30c might contribute to the sensitivity to cytarabine other hsa-mir-637 Osteoporosis 21880893 "miR-637 suppressed the growth of hMSCs and induced S-phase arrest. Expression of miR-637 was increased during adipocyte differentiation (AD) whereas it was decreased during osteoblast differentiation (OS), which suggests that miR-637 could act as a mediator of adipo-osteogenic differentiation. Disruption of this differentiation balance leads to various bone-related metabolic diseases, including osteoporosis. Therefore, miR-637 could contributes to osteoporosis." other hsa-mir-155 Atrophic Gastritis 21880981 MicroRNA-155 Is Essential for the T Cell-Mediated Control of Helicobacter pylori Infection and for the Induction of Chronic Gastritis and Colitis. other hsa-mir-155 Colitis 21880981 MicroRNA-155 Is Essential for the T Cell-Mediated Control of Helicobacter pylori Infection and for the Induction of Chronic Gastritis and Colitis. other hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 21881595 Systemic in vivo lentiviral delivery of miR-15a/16 reduces malignancy in the NZB de novo mouse model of chronic lymphocytic leukemia. other hsa-mir-16 "Leukemia, Lymphocytic, Chronic, B-Cell" 21881595 Systemic in vivo lentiviral delivery of miR-15a/16 reduces malignancy in the NZB de novo mouse model of chronic lymphocytic leukemia. other hsa-mir-92a-1 Colon Neoplasms 21883694 miR-92 is a key oncogenic component of the miR-17-92 cluster in colon cancer other hsa-mir-204 Hypertension 21890685 "These effects were associated with the inhibition of Src, STAT3, Pim1, NFATc2, and Survivin and the upregulation of BMPR2 and miR-204." other hsa-mir-181c Glioblastoma 21895872 Evaluation of the miR-181c in combination with miR-21 predicted time to progression within six months from diagnosis with 92% sensitivity and 81% specificity (p < 0.0001). The combination of miR-181c and miR-21 could be a very sensitive and specific test to identify patients at high risk of early progression after surgery. other hsa-mir-195 Glioblastoma 21895872 miR-195 (P=0.0124; log-rank test) has positively correlated with overall survival. other hsa-mir-196b Glioblastoma 21895872 miR-196b (P=0.0492; log-rank test) has positively correlated with overall survival. other hsa-mir-21 Glioblastoma 21895872 Evaluation of the miR-181c in combination with miR-21 predicted time to progression within six months from diagnosis with 92% sensitivity and 81% specificity (p < 0.0001). The combination of miR-181c and miR-21 could be a very sensitive and specific test to identify patients at high risk of early progression after surgery. other hsa-mir-149 Melanoma 21896753 "p53 directly up-regulates microRNA-149* (miR-149*) that in turn targets glycogen synthase kinase-3§Ø©ã resulting in increased expression of Mcl-1 and resistance to apoptosis in melanoma cells. Although deficiency in miR-149* undermined survival of melanoma cells and inhibited melanoma growth in a mouse xenograft model, elevated expression of miR-149* was found in fresh human metastatic melanoma isolates, which was associated with decreased glycogen synthase kinase-3§Ø©ãand increased Mcl-1." other hsa-mir-17 Periodontitis 21898695 MiR-17 Modulates Osteogenic Differentiation Through a Coherent Feed-Forward Loop in Mesenchymal Stem Cells Isolated from Periodontal Ligaments of Patients With Periodontitis. other hsa-mir-26a-1 "Leukemia, Myeloid, Acute" 21901171 Critical Role of c-Myc in Acute Myeloid Leukemia Involving Direct Regulation of miR-26a and Histone Methyltransferase EZH2. other hsa-mir-26a-2 "Leukemia, Myeloid, Acute" 21901171 Critical Role of c-Myc in Acute Myeloid Leukemia Involving Direct Regulation of miR-26a and Histone Methyltransferase EZH2. other hsa-mir-122 Hepatitis B Virus Infection 21902631 "Hybridization between the host-encoded, liver-specific microRNA (miR-122) and the 5'-untranslated region of HCV genome was shown to be required for effective viral RNA replication." other hsa-mir-122 Hepatitis B Virus Infection 21903935 "miR-122 may down-regulate HBV replication by binding to the viral target sequence, contributing to the persistent/chronic infection of HBV, and that HBV-induced modulation of miR-122 expression may represent a mechanism to facilitate viral pathogenesis." other hsa-mir-155 Multiple Sclerosis 21908875 "Expression of three neurosteroid synthesis enzyme-specific micro-RNAs (miR-338, miR-155 and miR-491) showed a bias towards induction in patients with multiple sclerosis (P < 0.05)." other hsa-mir-338 Multiple Sclerosis 21908875 "Expression of three neurosteroid synthesis enzyme-specific micro-RNAs (miR-338, miR-155 and miR-491) showed a bias towards induction in patients with multiple sclerosis (P < 0.05)." other hsa-mir-491 Multiple Sclerosis 21908875 "Expression of three neurosteroid synthesis enzyme-specific micro-RNAs (miR-338, miR-155 and miR-491) showed a bias towards induction in patients with multiple sclerosis (P < 0.05)." other hsa-mir-21 Cardiovascular Diseases [unspecific] 21909994 This review highlights the complex roles that miRNA-21 plays in cancer and cardiovascular diseases and its potential clinical applications. other hsa-mir-16-1 Pancreatic Neoplasms 21913185 miR-16 and miR-196a possessed an independent role in discriminating PCa (pancreatic cancer) from normal and CP. other hsa-mir-16-2 Pancreatic Neoplasms 21913185 miR-16 and miR-196a possessed an independent role in discriminating PCa (pancreatic cancer) from normal and CP. other hsa-mir-196a-1 Pancreatic Neoplasms 21913185 miR-16 and miR-196a possessed an independent role in discriminating PCa (pancreatic cancer) from normal and CP. other hsa-mir-196a-2 Pancreatic Neoplasms 21913185 miR-16 and miR-196a possessed an independent role in discriminating PCa (pancreatic cancer) from normal and CP. other hsa-mir-125b-1 Hailey-Hailey Disease 21913998 Oxidative stress activation of miR-125b is part of the molecular switch for Hailey-Hailey disease manifestation. other hsa-mir-122 "Carcinoma, Hepatocellular" 21917968 HepG2 cells expressing miR-122 support the entire hepatitis C virus life cycle. other hsa-mir-151a Anemia 21921042 Expression of miR-26b and miR-151-3p were both associated with HbF levels at MTD (maximum tolerated dose). other hsa-mir-26b Anemia 21921042 Expression of miR-26b and miR-151-3p were both associated with HbF levels at MTD (maximum tolerated dose). other hsa-mir-375 "Squamous Cell Carcinoma, Maxillary Sinus" 21922130 Tumor suppressive microRNA-375 regulates lactate dehydrogenase B in maxillary sinus squamous cell carcinoma. other hsa-mir-708 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 21926415 miR-708 was also found to be associated with the in vivo glucocorticoid therapy response and with disease risk stratification. other hsa-mir-144 Colorectal Carcinoma 21929751 Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism. other hsa-mir-150 Lung Neoplasms 21935578 Anti-miR-150 vector can regress A549 lung cancer tumors. other hsa-mir-15a Multiple Myeloma 21936961 Suppressing miRNA-15a/-16 expression by interleukin-6 enhances drug-resistance in myeloma cells. other hsa-mir-16-1 Multiple Myeloma 21936961 Suppressing miRNA-15a/-16 expression by interleukin-6 enhances drug-resistance in myeloma cells. other hsa-mir-15b Glioma 21937590 "MiR-15b and miR-21 were differentially expressed in CSF (cerebrospinal fluid) samples from patients with gliomas, compared to control subjects with various neurologic disorders, including patients with primary CNS lymphoma and carcinomatous brain metastases.In conclusion, the results of this pilot study demonstrate that miR-15b and miR-21 are markers for gliomas, which can be assessed in the CSF by means of qRT-PCR." other hsa-mir-21 Glioma 21937590 "MiR-15b and miR-21 were differentially expressed in CSF (cerebrospinal fluid) samples from patients with gliomas, compared to control subjects with various neurologic disorders, including patients with primary CNS lymphoma and carcinomatous brain metastases.In conclusion, the results of this pilot study demonstrate that miR-15b and miR-21 are markers for gliomas, which can be assessed in the CSF by means of qRT-PCR." other hsa-mir-21 Melanoma 21940630 MicroRNA-21 regulates the metastatic behavior of B16 melanoma cells. other hsa-mir-451a "Leukemia, Myeloid, Chronic" 21944890 miRNA-451 is a putative predictor marker of Imatinib therapy response in chronic myeloid leukemia. other hsa-mir-126 Atherosclerosis 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-126 Cardiomegaly 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-126 Coronary Artery Disease 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-126 Diabetes Mellitus 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-126 Hypertension 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-155 Atherosclerosis 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-155 Cardiomegaly 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-155 Coronary Artery Disease 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-155 Diabetes Mellitus 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-155 Hypertension 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-17 Atherosclerosis 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-17 Cardiomegaly 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-17 Coronary Artery Disease 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-17 Diabetes Mellitus 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-17 Hypertension 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-221 Atherosclerosis 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-221 Cardiomegaly 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-221 Coronary Artery Disease 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-221 Diabetes Mellitus 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-221 Hypertension 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-222 Atherosclerosis 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-222 Cardiomegaly 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-222 Coronary Artery Disease 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-222 Diabetes Mellitus 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-222 Hypertension 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-31 Atherosclerosis 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-31 Cardiomegaly 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-31 Coronary Artery Disease 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-31 Diabetes Mellitus 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-31 Hypertension 21946298 "Other known miRNAs,including miR-31, miR17-3p, miR-155, miR-221, miR-222, and miR-126, are important factors in the regulation of vascular inflammation." other hsa-mir-548d-1 Pancreatic Neoplasms 21946813 MicroRNA miR-548d Is a Superior Regulator in Pancreatic Cancer. other hsa-mir-548d-2 Pancreatic Neoplasms 21946813 MicroRNA miR-548d Is a Superior Regulator in Pancreatic Cancer. other hsa-mir-146a Gastric Neoplasms 21947847 H. pylori related proinflammatory cytokines contribute to the induction of miR-146a in human gastric epithelial cells. other hsa-mir-451a Colorectal Carcinoma 21948564 "Microrna-451 is Involved in the Self-Renewal, Tumorigenicity and Chemoresistance of Colorectal Cancer Stem Cells." other hsa-mir-126 Myocardial Infarction 21949332 "miR-223 and miR-197 showed positive associations (multivariable HR 2.19 [95% CI 1.26 to 3.83], p=0.006, and 1.79 [95% CI 1.00 to 3.20], p=0.049) while miR-126 was inversely correlated with disease risk (multivariable HR 0.40 [95% CI 0.22 to 0.73], p=0.003)." other hsa-mir-197 Myocardial Infarction 21949332 "miR-223 and miR-197 showed positive associations (multivariable HR 2.19 [95% CI 1.26 to 3.83], p=0.006, and 1.79 [95% CI 1.00 to 3.20], p=0.049) while miR-126 was inversely correlated with disease risk (multivariable HR 0.40 [95% CI 0.22 to 0.73], p=0.003)." other hsa-mir-223 Myocardial Infarction 21949332 "miR-223 and miR-197 showed positive associations (multivariable HR 2.19 [95% CI 1.26 to 3.83], p=0.006, and 1.79 [95% CI 1.00 to 3.20], p=0.049) while miR-126 was inversely correlated with disease risk (multivariable HR 0.40 [95% CI 0.22 to 0.73], p=0.003)." other hsa-mir-34b Melanoma 21949788 "Expression of miR-34b reduced cell invasion and motility rates of both WM1552C and A375, suggesting that the enhanced cell invasiveness and motility observed in metastatic melanoma cells may be related to their reduced expression of miR-34b." other hsa-mir-10a Atherosclerosis 21952822 Endothelial inflammation is critically regulated by miRNAs such as miR-126 and miR-10a in vitro and in vivo. other hsa-mir-126 Atherosclerosis 21952822 Endothelial inflammation is critically regulated by miRNAs such as miR-126 and miR-10a in vitro and in vivo. other hsa-mir-146a Systemic Lupus Erythematosus 21952984 miR-146a has a role in the pathogenesis of systemic lupus erythematosus with atherosclerosis. other hsa-mir-135b Pancreatic Neoplasms 21953293 "Using relative qRT-PCR to measure miR-135b normalized to miR-24 in 75 FFPE specimens (42 PDAC and 33 CP) covering a broad range of tumor content, the authors discriminated CP from PDAC with a sensitivity and specificity of 92.9% [95%CI=(80.5,98.5)] and 93.4% [95%CI=(79.8,99.3)], respectively. Therefore, miR-135b could be a novel biomarker for pancreatic ductal adenocarcinoma." other hsa-mir-200b Lung Neoplasms 21954225 "Stably expressing microRNA-200b in As-p53lowHBECs (human bronchial epithelial cell) abolished Akt and Erk1/2 activation, and completely suppressed cell migration and invasion." other hsa-mir-34a Dementia 21956116 miR-34a was among the most highly induced miRNAs in HIV-1 Tat-treated neurons. other hsa-mir-34a Ewing Sarcoma 21960059 "miR-34a and miR490-3p achieved sufficient statistical power to predict prognosis.Patients with the highest expression of miR-34a did not experience adverse events in 5 years; in contrast, patients with the lowest expression recurred within two years." other hsa-mir-490 Ewing Sarcoma 21960059 miR-34a and miR490-3p achieved sufficient statistical power to predict prognosis. other hsa-mir-125b-1 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-125b-2 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-143 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-145 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-149 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-16-1 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-16-2 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-17 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-181a-2 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-183 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-206 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-208a Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-208b Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-20a Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-20b Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-22 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-224 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-25 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-26a-1 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-26a-2 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-29a Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-29c Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-30c-1 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-30c-2 Glioblastoma 21961478 altered expression after Polyunsaturated fatty acids (PUFAs) treatment other hsa-mir-126 Arteriosclerosis Obliterans 21969012 "Muscle-enriched miR-499 and miR-133a are released from the heart into the coronary circulation on myocardial injury, whereas the vascular miR-126 is consumed during transcoronary passage. " other hsa-mir-133a Arteriosclerosis Obliterans 21969012 "Muscle-enriched miR-499 and miR-133a are released from the heart into the coronary circulation on myocardial injury, whereas the vascular miR-126 is consumed during transcoronary passage. " other hsa-mir-499 Arteriosclerosis Obliterans 21969012 "Muscle-enriched miR-499 and miR-133a are released from the heart into the coronary circulation on myocardial injury, whereas the vascular miR-126 is consumed during transcoronary passage. " other hsa-mir-142 Hepatitis C Virus Infection 21970718 "miR-128a, miR-196a and miR-142-3p were modulated in a concerted fashion in all three HCV clones" other hsa-mir-196a-1 Hepatitis C Virus Infection 21970718 "miR-128a, miR-196a and miR-142-3p were modulated in a concerted fashion in all three HCV clones" other hsa-mir-331 Prostate Neoplasms 21971048 The RNA-binding protein HuR opposes the repression of ERBB-2 expression by miR-331-3p in prostate cancer cells. other hsa-mir-148a Ovarian Neoplasms 21971665 Ovarian Altered expression of miR-152 and miR-148a in ovarian cancer is related to cell proliferation. other hsa-mir-152 Ovarian Neoplasms 21971665 Ovarian Altered expression of miR-152 and miR-148a in ovarian cancer is related to cell proliferation. other hsa-mir-212 Heart Failure 21977024 "Conversely, alcohol-mediated inhibition of mTOR/S6K1, down-regulation of INS receptor and growth-inhibitory mir-200 family, and upregulation of mir-212 that promotes fetal gene program may exacerbate CRS-related cardiomyopathy." other hsa-mir-146a Prostate Neoplasms 21980038 "Microdissected epithelial structures with CgA-positive cell clusters exhibited a more than 5- and 7-fold lower expression of miR-146a and miR-146b-5p than their CgA-negative counterparts. As focal basal cell layer disruptions and the reduction or loss of miR-146a and miR-146b-5p has been documented to correlate with prostate tumor invasion and hormone refractoriness, our findings suggest that aberrant CgA expression in epithelial structures with FBCLD may represent an early sign of these events." other hsa-mir-126 Prostate Neoplasms 21980368 "miR-16, miR-34a, miR-126*, miR-145, miR-205 have been linked to prostate cancer metastasis" other hsa-mir-145 Prostate Neoplasms 21980368 "miR-16, miR-34a, miR-126*, miR-145, miR-205 have been linked to prostate cancer metastasis" other hsa-mir-16-1 Prostate Neoplasms 21980368 "miR-16, miR-34a, miR-126*, miR-145, miR-205 have been linked to prostate cancer metastasis" other hsa-mir-16-2 Prostate Neoplasms 21980368 "miR-16, miR-34a, miR-126*, miR-145, miR-205 have been linked to prostate cancer metastasis" other hsa-mir-205 Prostate Neoplasms 21980368 "miR-16, miR-34a, miR-126*, miR-145, miR-205 have been linked to prostate cancer metastasis" other hsa-mir-34a Prostate Neoplasms 21980368 "miR-16, miR-34a, miR-126*, miR-145, miR-205 have been linked to prostate cancer metastasis" other hsa-mir-146a "Carcinoma, Hepatocellular" 21982769 miR-146a suppresses the sensitivity to interferon-a in hepatocellular carcinoma cells. other hsa-mir-206 "Carcinoma, Endometrioid Endometrial" 21983130 Expression of the tumor suppressor miR-206 is associated with cellular proliferative inhibition and impairs invasion in ER§Ø©ãpositive endometrioid adenocarcinoma. other hsa-mir-205 Mesothelioma 21983934 "our findings indicate that epithelial-mesenchymal transition has a significant part in the morphological features of malignant mesothelioma. In particular, miR-205 down-regulation correlated ignificantly with both a mesenchymal phenotype and a more aggressive behavior." other hsa-mir-15a "Lymphoma, Mantle-Cell" 22002311 Myc represses miR-15a/miR-16-1 expression through recruitment of HDAC3 in mantle cell and other non-Hodgkin B-cell lymphomas. other hsa-mir-16-1 "Lymphoma, Mantle-Cell" 22002311 Myc represses miR-15a/miR-16-1 expression through recruitment of HDAC3 in mantle cell and other non-Hodgkin B-cell lymphomas. other hsa-mir-181b Breast Neoplasms 22009755 "In conclusion, miR-221/222 and -181b facilitate growth factor signaling in tamoxifen-resistant breast cancer by down-regulating TIMP3, and corresponding anti-miRs can be used to render these tumors responsive to tamoxifen." other hsa-mir-221 Breast Neoplasms 22009755 "In conclusion, miR-221/222 and -181b facilitate growth factor signaling in tamoxifen-resistant breast cancer by down-regulating TIMP3, and corresponding anti-miRs can be used to render these tumors responsive to tamoxifen." other hsa-mir-222 Breast Neoplasms 22009755 "In conclusion, miR-221/222 and -181b facilitate growth factor signaling in tamoxifen-resistant breast cancer by down-regulating TIMP3, and corresponding anti-miRs can be used to render these tumors responsive to tamoxifen." other hsa-mir-101-1 "Carcinoma, Lung, Non-Small-Cell" 22014955 "The endogenous miR-101 level was similar or lower in 13 NSCLC cell lines but was 11-fold higher in one cell line (H157) than in NL20 cells. Although ectopic miR-101 efficiently decreased the ATM and DNA-PKcs levels and increased the radiosensitization level in H1299, H1975, and A549 cells, it did not change the levels of the miR-101 targets or radiosensitivity in H157 cells." other hsa-mir-101-2 "Carcinoma, Lung, Non-Small-Cell" 22014955 "The endogenous miR-101 level was similar or lower in 13 NSCLC cell lines but was 11-fold higher in one cell line (H157) than in NL20 cells. Although ectopic miR-101 efficiently decreased the ATM and DNA-PKcs levels and increased the radiosensitization level in H1299, H1975, and A549 cells, it did not change the levels of the miR-101 targets or radiosensitivity in H157 cells." other hsa-mir-15b "Leukemia, Myeloid, Acute" 22015065 "miR-590-5p, miR-219-5p, miR-15b and miR-628-5p are commonly regulated by IL-3, GM-CSF and G-CSF in acute myeloid leukemia." other hsa-mir-219 "Leukemia, Myeloid, Acute" 22015065 "miR-590-5p, miR-219-5p, miR-15b and miR-628-5p are commonly regulated by IL-3, GM-CSF and G-CSF in acute myeloid leukemia." other hsa-mir-219-1 "Leukemia, Myeloid, Acute" 22015065 "miR-590-5p, miR-219-5p, miR-15b and miR-628-5p are commonly regulated by IL-3, GM-CSF and G-CSF in acute myeloid leukemia." other hsa-mir-590 "Leukemia, Myeloid, Acute" 22015065 "miR-590-5p, miR-219-5p, miR-15b and miR-628-5p are commonly regulated by IL-3, GM-CSF and G-CSF in acute myeloid leukemia." other hsa-mir-628 "Leukemia, Myeloid, Acute" 22015065 "miR-590-5p, miR-219-5p, miR-15b and miR-628-5p are commonly regulated by IL-3, GM-CSF and G-CSF in acute myeloid leukemia." other hsa-mir-27a Gastric Neoplasms 22018270 miR-27 promotes human gastric cancer cell metastasis by inducing epithelial-to-mesenchymal transition. other hsa-mir-27b Gastric Neoplasms 22018270 miR-27 promotes human gastric cancer cell metastasis by inducing epithelial-to-mesenchymal transition. other hsa-mir-10b Breast Neoplasms 22020939 Cysteine rich 61-connective tissue growth factor-nephroblastoma-overexpressed 5 (CCN5)/Wnt-1-induced signaling protein-2(WISP-2) regulates microRNA-10b via hypoxia-inducible factor-1{alpha}-TWIST signaling networks in human breast cancer cells. other hsa-mir-340 Coronary Artery Disease 22022480 Platelets in Patients with Premature Coronary Artery Disease Exhibit Upregulation of miRNA340* and miRNA624*. other hsa-mir-624 Coronary Artery Disease 22022480 Platelets in Patients with Premature Coronary Artery Disease Exhibit Upregulation of miRNA340* and miRNA624*. other hsa-mir-335 Breast Neoplasms 22034498 Aryl Hydrocarbon Receptor (AHR) Agonists Induce MicroRNA-335 Expression and Inhibit Lung Metastasis of Estrogen Receptor Negative Breast Cancer Cells. other hsa-mir-101-1 "Carcinoma, Hepatocellular" 22035408 "Benzothiazole based compounds exhibited effective cytotoxicity at 4 M concentration and have shown G1 cell cycle arrest with decrease in levels of G1 cell cycle proteins such as cyclin D1 and Skp2. Involvement of tumour suppressor proteins such as PTEN and p53 was studied. Interestingly these compounds displayed decrease in the phosphorylated forms of AKT, p38 MAPK and ERK1/2 which play a vital role in cell proliferation. Compounds have exhibited strong and significant effect on the expression of micro RNAs such as miR-195a & miR-101-1 which regulate hepatic cell proliferation." other hsa-mir-15b Anus Neoplasm 22045185 "The expression of miR-15b was shown to be highly correlated with that of five selected E2F-induced genes (CCNA2, CCNB1, CCNB2, MSH6 and MCM7). A knockdown of HPV16 E7 resulted in decreased levels of miR-15b in Ca Ski cells.Conclusion:MiR-15b expression correlates with E2F-regulated genes in anal carcinoma and appears to be part of the E2F-regulatory network." other hsa-mir-200c "Carcinoma, Lung, Non-Small-Cell" 22045191 "Ectopic expression of mir-200c alters expression of EMT proteins, sensitivity to erlotinib, and migration in lung cells." other hsa-mir-505 Breast Neoplasms 22051041 "miR-505 is a novel tumor suppressive miRNA and inhibits cell proliferation by inducing apoptosis. We also find that Akt3, correlate inversely with miR-505, modulates drug sensitivity in MCF7-ADR." other hsa-mir-150 Colorectal Carcinoma 22052060 "Only one miR-150 was found to show a decrease in expression levels in the three tissue groups (normal, adenoma and cancer tissue) in parallel with increasing carcinogenesis of the colorectal tissue. In both ISH and qRT-PCR analysis, tumour tissue had reduced levels of miR-150 expression compared with paired non-cancerous tissue, which indicated that the levels of miR-150 expression were associated with CRC. Moreover, patients whose tumours had low miR-150 expression had shorter survival and a worse response to adjuvant chemotherapy than patients whose tumours had high miRNA expression." other hsa-mir-378a "Carcinoma, Lung, Non-Small-Cell" 22052152 "MicroRNA-378 is associated with non-small cell lung cancer brain metastasis by promoting cell migration, invasion and tumor angiogenesis." other hsa-mir-34b "Adenocarcinoma, Endometrial" 22052540 MicroRNA-34b functions as a potential tumor suppressor in endometrial serous adenocarcinoma. other hsa-mir-155 Ischemia 22052914 Inhibition of miR-15 Protects Against Cardiac Ischemic Injury. other hsa-let-7d Ependymoma 22053178 "Three miRNAs (let-7d, miR-596 and miR-367) strongly correlate to overall survival." other hsa-mir-203 Ependymoma 22053178 miR-203 is an independent marker for relapse compared to the parameters that are currently used. other hsa-mir-367 Ependymoma 22053178 "Three miRNAs (let-7d, miR-596 and miR-367) strongly correlate to overall survival." other hsa-mir-596 Ependymoma 22053178 "Three miRNAs (let-7d, miR-596 and miR-367) strongly correlate to overall survival." other hsa-mir-30d Ovarian Neoplasms 22058146 A combined array-based comparative genomic hybridization (aCGH) and functional library screening approach identifies mir-30d as an oncomir in cancer. other hsa-mir-200a "Carcinoma, Renal Cell" 22082152 MiRNA-9 and MiRNA-200a distinguish hemangioblastomas from metastatic clear cell renal cell carcinomas in the CNS. other hsa-mir-9-1 "Carcinoma, Renal Cell" 22082152 MiRNA-9 and MiRNA-200a distinguish hemangioblastomas from metastatic clear cell renal cell carcinomas in the CNS. other hsa-mir-9-2 "Carcinoma, Renal Cell" 22082152 MiRNA-9 and MiRNA-200a distinguish hemangioblastomas from metastatic clear cell renal cell carcinomas in the CNS. other hsa-mir-9-3 "Carcinoma, Renal Cell" 22082152 MiRNA-9 and MiRNA-200a distinguish hemangioblastomas from metastatic clear cell renal cell carcinomas in the CNS. other hsa-mir-23a Hypertrophy 22084234 Cardiac hypertrophy is positively regulated by miR-23a. other hsa-let-7a-1 Pancreatic Neoplasms 22086681 "We found that metformin significantly decreased cell survival, clonogenicity, wound healing capacity, sphere-forming capacity (pancreatospheres), and increased disintegration of pancreatospheres in both gemcitabine-sensitive and gemcitabine-resistant PC cells. Metformin also decreased the expression of CSC markers, CD44, EpCAM, EZH2, Notch-1, Nanog and Oct4, and caused re-expression of miRNAs (let-7a, b, miR-26a, miR-101, and miR-200b, c) that are typically lost in PC and especially in pancreatospheres. We also found that re-expression of miR-26a by transfection led to decreased expression of EZH2 and EpCAM in PC cells." other hsa-let-7a-2 Pancreatic Neoplasms 22086681 "We found that metformin significantly decreased cell survival, clonogenicity, wound healing capacity, sphere-forming capacity (pancreatospheres), and increased disintegration of pancreatospheres in both gemcitabine-sensitive and gemcitabine-resistant PC cells. Metformin also decreased the expression of CSC markers, CD44, EpCAM, EZH2, Notch-1, Nanog and Oct4, and caused re-expression of miRNAs (let-7a, b, miR-26a, miR-101, and miR-200b, c) that are typically lost in PC and especially in pancreatospheres. We also found that re-expression of miR-26a by transfection led to decreased expression of EZH2 and EpCAM in PC cells." other hsa-let-7a-3 Pancreatic Neoplasms 22086681 "We found that metformin significantly decreased cell survival, clonogenicity, wound healing capacity, sphere-forming capacity (pancreatospheres), and increased disintegration of pancreatospheres in both gemcitabine-sensitive and gemcitabine-resistant PC cells. Metformin also decreased the expression of CSC markers, CD44, EpCAM, EZH2, Notch-1, Nanog and Oct4, and caused re-expression of miRNAs (let-7a, b, miR-26a, miR-101, and miR-200b, c) that are typically lost in PC and especially in pancreatospheres. We also found that re-expression of miR-26a by transfection led to decreased expression of EZH2 and EpCAM in PC cells." other hsa-let-7b Pancreatic Neoplasms 22086681 "We found that metformin significantly decreased cell survival, clonogenicity, wound healing capacity, sphere-forming capacity (pancreatospheres), and increased disintegration of pancreatospheres in both gemcitabine-sensitive and gemcitabine-resistant PC cells. Metformin also decreased the expression of CSC markers, CD44, EpCAM, EZH2, Notch-1, Nanog and Oct4, and caused re-expression of miRNAs (let-7a, b, miR-26a, miR-101, and miR-200b, c) that are typically lost in PC and especially in pancreatospheres. We also found that re-expression of miR-26a by transfection led to decreased expression of EZH2 and EpCAM in PC cells." other hsa-mir-101-1 Pancreatic Neoplasms 22086681 "We found that metformin significantly decreased cell survival, clonogenicity, wound healing capacity, sphere-forming capacity (pancreatospheres), and increased disintegration of pancreatospheres in both gemcitabine-sensitive and gemcitabine-resistant PC cells. Metformin also decreased the expression of CSC markers, CD44, EpCAM, EZH2, Notch-1, Nanog and Oct4, and caused re-expression of miRNAs (let-7a, b, miR-26a, miR-101, and miR-200b, c) that are typically lost in PC and especially in pancreatospheres. We also found that re-expression of miR-26a by transfection led to decreased expression of EZH2 and EpCAM in PC cells." other hsa-mir-101-2 Pancreatic Neoplasms 22086681 "We found that metformin significantly decreased cell survival, clonogenicity, wound healing capacity, sphere-forming capacity (pancreatospheres), and increased disintegration of pancreatospheres in both gemcitabine-sensitive and gemcitabine-resistant PC cells. Metformin also decreased the expression of CSC markers, CD44, EpCAM, EZH2, Notch-1, Nanog and Oct4, and caused re-expression of miRNAs (let-7a, b, miR-26a, miR-101, and miR-200b, c) that are typically lost in PC and especially in pancreatospheres. We also found that re-expression of miR-26a by transfection led to decreased expression of EZH2 and EpCAM in PC cells." other hsa-mir-200b Pancreatic Neoplasms 22086681 "We found that metformin significantly decreased cell survival, clonogenicity, wound healing capacity, sphere-forming capacity (pancreatospheres), and increased disintegration of pancreatospheres in both gemcitabine-sensitive and gemcitabine-resistant PC cells. Metformin also decreased the expression of CSC markers, CD44, EpCAM, EZH2, Notch-1, Nanog and Oct4, and caused re-expression of miRNAs (let-7a, b, miR-26a, miR-101, and miR-200b, c) that are typically lost in PC and especially in pancreatospheres. We also found that re-expression of miR-26a by transfection led to decreased expression of EZH2 and EpCAM in PC cells." other hsa-mir-200c Pancreatic Neoplasms 22086681 "We found that metformin significantly decreased cell survival, clonogenicity, wound healing capacity, sphere-forming capacity (pancreatospheres), and increased disintegration of pancreatospheres in both gemcitabine-sensitive and gemcitabine-resistant PC cells. Metformin also decreased the expression of CSC markers, CD44, EpCAM, EZH2, Notch-1, Nanog and Oct4, and caused re-expression of miRNAs (let-7a, b, miR-26a, miR-101, and miR-200b, c) that are typically lost in PC and especially in pancreatospheres. We also found that re-expression of miR-26a by transfection led to decreased expression of EZH2 and EpCAM in PC cells." other hsa-mir-26a-1 Pancreatic Neoplasms 22086681 "We found that metformin significantly decreased cell survival, clonogenicity, wound healing capacity, sphere-forming capacity (pancreatospheres), and increased disintegration of pancreatospheres in both gemcitabine-sensitive and gemcitabine-resistant PC cells. Metformin also decreased the expression of CSC markers, CD44, EpCAM, EZH2, Notch-1, Nanog and Oct4, and caused re-expression of miRNAs (let-7a, b, miR-26a, miR-101, and miR-200b, c) that are typically lost in PC and especially in pancreatospheres. We also found that re-expression of miR-26a by transfection led to decreased expression of EZH2 and EpCAM in PC cells." other hsa-mir-26a-2 Pancreatic Neoplasms 22086681 "We found that metformin significantly decreased cell survival, clonogenicity, wound healing capacity, sphere-forming capacity (pancreatospheres), and increased disintegration of pancreatospheres in both gemcitabine-sensitive and gemcitabine-resistant PC cells. Metformin also decreased the expression of CSC markers, CD44, EpCAM, EZH2, Notch-1, Nanog and Oct4, and caused re-expression of miRNAs (let-7a, b, miR-26a, miR-101, and miR-200b, c) that are typically lost in PC and especially in pancreatospheres. We also found that re-expression of miR-26a by transfection led to decreased expression of EZH2 and EpCAM in PC cells." other hsa-mir-140 "Hand, Foot And Mouth Disease" 22087245 "A receiver operating characteristic (ROC) curve analysis revealed that six serum miRNAs (miR-148a, miR-143, miR-324-3p, miR-628-3p, miR-140-5p, and miR-362-3p) were able to discriminate patients with enterovirus infections from healthy controls with area under curve (AUC) values ranged from 0.828 to 0.934. The combined six miRNA using multiple logistic regression analysis provided not only a sensitivity of 97.1% and a specificity of 92.7% but also a unique profile that differentiated enterovirial infections from other microbial infections. Expression levels of five miRNAs (miR-148a, miR-143, miR-324-3p, miR-545, and miR-140-5p) were significantly increased in patients with CVA16 versus those with EV71 (p<0.05). Combination of miR-545, miR-324-3p, and miR-143 possessed a moderate ability to discrimination between CVA16 and EV71 with an AUC value of 0.761." other hsa-mir-143 "Hand, Foot And Mouth Disease" 22087245 "A receiver operating characteristic (ROC) curve analysis revealed that six serum miRNAs (miR-148a, miR-143, miR-324-3p, miR-628-3p, miR-140-5p, and miR-362-3p) were able to discriminate patients with enterovirus infections from healthy controls with area under curve (AUC) values ranged from 0.828 to 0.934. The combined six miRNA using multiple logistic regression analysis provided not only a sensitivity of 97.1% and a specificity of 92.7% but also a unique profile that differentiated enterovirial infections from other microbial infections. Expression levels of five miRNAs (miR-148a, miR-143, miR-324-3p, miR-545, and miR-140-5p) were significantly increased in patients with CVA16 versus those with EV71 (p<0.05). Combination of miR-545, miR-324-3p, and miR-143 possessed a moderate ability to discrimination between CVA16 and EV71 with an AUC value of 0.761." other hsa-mir-148a "Hand, Foot And Mouth Disease" 22087245 "A receiver operating characteristic (ROC) curve analysis revealed that six serum miRNAs (miR-148a, miR-143, miR-324-3p, miR-628-3p, miR-140-5p, and miR-362-3p) were able to discriminate patients with enterovirus infections from healthy controls with area under curve (AUC) values ranged from 0.828 to 0.934. The combined six miRNA using multiple logistic regression analysis provided not only a sensitivity of 97.1% and a specificity of 92.7% but also a unique profile that differentiated enterovirial infections from other microbial infections. Expression levels of five miRNAs (miR-148a, miR-143, miR-324-3p, miR-545, and miR-140-5p) were significantly increased in patients with CVA16 versus those with EV71 (p<0.05). Combination of miR-545, miR-324-3p, and miR-143 possessed a moderate ability to discrimination between CVA16 and EV71 with an AUC value of 0.761." other hsa-mir-324 "Hand, Foot And Mouth Disease" 22087245 "A receiver operating characteristic (ROC) curve analysis revealed that six serum miRNAs (miR-148a, miR-143, miR-324-3p, miR-628-3p, miR-140-5p, and miR-362-3p) were able to discriminate patients with enterovirus infections from healthy controls with area under curve (AUC) values ranged from 0.828 to 0.934. The combined six miRNA using multiple logistic regression analysis provided not only a sensitivity of 97.1% and a specificity of 92.7% but also a unique profile that differentiated enterovirial infections from other microbial infections. Expression levels of five miRNAs (miR-148a, miR-143, miR-324-3p, miR-545, and miR-140-5p) were significantly increased in patients with CVA16 versus those with EV71 (p<0.05). Combination of miR-545, miR-324-3p, and miR-143 possessed a moderate ability to discrimination between CVA16 and EV71 with an AUC value of 0.761." other hsa-mir-362 "Hand, Foot And Mouth Disease" 22087245 "A receiver operating characteristic (ROC) curve analysis revealed that six serum miRNAs (miR-148a, miR-143, miR-324-3p, miR-628-3p, miR-140-5p, and miR-362-3p) were able to discriminate patients with enterovirus infections from healthy controls with area under curve (AUC) values ranged from 0.828 to 0.934. The combined six miRNA using multiple logistic regression analysis provided not only a sensitivity of 97.1% and a specificity of 92.7% but also a unique profile that differentiated enterovirial infections from other microbial infections. Expression levels of five miRNAs (miR-148a, miR-143, miR-324-3p, miR-545, and miR-140-5p) were significantly increased in patients with CVA16 versus those with EV71 (p<0.05). Combination of miR-545, miR-324-3p, and miR-143 possessed a moderate ability to discrimination between CVA16 and EV71 with an AUC value of 0.761." other hsa-mir-545 "Hand, Foot And Mouth Disease" 22087245 "A receiver operating characteristic (ROC) curve analysis revealed that six serum miRNAs (miR-148a, miR-143, miR-324-3p, miR-628-3p, miR-140-5p, and miR-362-3p) were able to discriminate patients with enterovirus infections from healthy controls with area under curve (AUC) values ranged from 0.828 to 0.934. The combined six miRNA using multiple logistic regression analysis provided not only a sensitivity of 97.1% and a specificity of 92.7% but also a unique profile that differentiated enterovirial infections from other microbial infections. Expression levels of five miRNAs (miR-148a, miR-143, miR-324-3p, miR-545, and miR-140-5p) were significantly increased in patients with CVA16 versus those with EV71 (p<0.05). Combination of miR-545, miR-324-3p, and miR-143 possessed a moderate ability to discrimination between CVA16 and EV71 with an AUC value of 0.761." other hsa-mir-628 "Hand, Foot And Mouth Disease" 22087245 "A receiver operating characteristic (ROC) curve analysis revealed that six serum miRNAs (miR-148a, miR-143, miR-324-3p, miR-628-3p, miR-140-5p, and miR-362-3p) were able to discriminate patients with enterovirus infections from healthy controls with area under curve (AUC) values ranged from 0.828 to 0.934. The combined six miRNA using multiple logistic regression analysis provided not only a sensitivity of 97.1% and a specificity of 92.7% but also a unique profile that differentiated enterovirial infections from other microbial infections. Expression levels of five miRNAs (miR-148a, miR-143, miR-324-3p, miR-545, and miR-140-5p) were significantly increased in patients with CVA16 versus those with EV71 (p<0.05). Combination of miR-545, miR-324-3p, and miR-143 possessed a moderate ability to discrimination between CVA16 and EV71 with an AUC value of 0.761." other hsa-mir-133a-1 Lung Neoplasms 22089643 Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma. other hsa-mir-15b Heart Failure 22093502 "The real-time PCR confirmed lower expression in LV recovery patients for 4 miRs (15b, -1.5-fold; 23a, -2.2-fold; 26a, -1.4-fold; and 195, -1.8-fold; all p < 0.04 vs. VAD dependent). The validation cohort similarly showed lower miRs expression in LV recovery patients (23a, -1.8-fold; and 195, -1.5-fold; both p < 0.03). Furthermore, miR 23a and 195 expression in nonfailing hearts was similar to LV recovery patients (both p < 0.04 vs. VAD dependent)." other hsa-mir-195 Heart Failure 22093502 "The real-time PCR confirmed lower expression in LV recovery patients for 4 miRs (15b, -1.5-fold; 23a, -2.2-fold; 26a, -1.4-fold; and 195, -1.8-fold; all p < 0.04 vs. VAD dependent). The validation cohort similarly showed lower miRs expression in LV recovery patients (23a, -1.8-fold; and 195, -1.5-fold; both p < 0.03). Furthermore, miR 23a and 195 expression in nonfailing hearts was similar to LV recovery patients (both p < 0.04 vs. VAD dependent)." other hsa-mir-23a Heart Failure 22093502 "The real-time PCR confirmed lower expression in LV recovery patients for 4 miRs (15b, -1.5-fold; 23a, -2.2-fold; 26a, -1.4-fold; and 195, -1.8-fold; all p < 0.04 vs. VAD dependent). The validation cohort similarly showed lower miRs expression in LV recovery patients (23a, -1.8-fold; and 195, -1.5-fold; both p < 0.03). Furthermore, miR 23a and 195 expression in nonfailing hearts was similar to LV recovery patients (both p < 0.04 vs. VAD dependent)." other hsa-mir-26a-1 Heart Failure 22093502 "The real-time PCR confirmed lower expression in LV recovery patients for 4 miRs (15b, -1.5-fold; 23a, -2.2-fold; 26a, -1.4-fold; and 195, -1.8-fold; all p < 0.04 vs. VAD dependent). The validation cohort similarly showed lower miRs expression in LV recovery patients (23a, -1.8-fold; and 195, -1.5-fold; both p < 0.03). Furthermore, miR 23a and 195 expression in nonfailing hearts was similar to LV recovery patients (both p < 0.04 vs. VAD dependent)." other hsa-mir-26a-2 Heart Failure 22093502 "The real-time PCR confirmed lower expression in LV recovery patients for 4 miRs (15b, -1.5-fold; 23a, -2.2-fold; 26a, -1.4-fold; and 195, -1.8-fold; all p < 0.04 vs. VAD dependent). The validation cohort similarly showed lower miRs expression in LV recovery patients (23a, -1.8-fold; and 195, -1.5-fold; both p < 0.03). Furthermore, miR 23a and 195 expression in nonfailing hearts was similar to LV recovery patients (both p < 0.04 vs. VAD dependent)." other hsa-mir-26a-1 Breast Neoplasms 22094936 High miR-26a and low CDC2 levels associate with decreased EZH2 expression and with favorable outcome on tamoxifen in metastatic breast cancer. other hsa-mir-26a-2 Breast Neoplasms 22094936 High miR-26a and low CDC2 levels associate with decreased EZH2 expression and with favorable outcome on tamoxifen in metastatic breast cancer. other hsa-mir-155 Lymphoma 22096245 miR-155 regulates HGAL expression and increases lymphoma cell motility. other hsa-mir-141 Ovarian Neoplasms 22101765 miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response. other hsa-mir-200a Ovarian Neoplasms 22101765 miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response. other hsa-mir-34a Melanoma 22102694 "Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress induced ligand of the natural killer cell receptor NKG2D." other hsa-mir-34c Melanoma 22102694 "Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress induced ligand of the natural killer cell receptor NKG2D." other hsa-mir-34a Breast Neoplasms 22102859 MiR-34a Expression Has an Effect for Lower Risk of Metastasis and Associates with Expression Patterns Predicting Clinical Outcome in Breast Cancer. other hsa-mir-23b Colon Neoplasms 22109528 Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis. other hsa-mir-1 Heart Failure 22110643 "We conclude that miR-1 and -499 play differential roles in cardiac differentiation of hESCs in a context-dependent fashion. While miR-499 promotes ventricular specification of hESCs, miR-1 serves to facilitate electrophysiological maturation." other hsa-mir-499 Heart Failure 22110643 "We conclude that miR-1 and -499 play differential roles in cardiac differentiation of hESCs in a context-dependent fashion. While miR-499 promotes ventricular specification of hESCs, miR-1 serves to facilitate electrophysiological maturation." other hsa-mir-126 Myocardial Infarction 22113756 "Transplantation of MSCs transfected with miR-126 can improve angiogenesis and cardiac function in the infarcted area of the hearts of mice, which may be due to stimulation of the AKT/ERK-related pathway." other hsa-mir-155 Waldenstrom Macroglobulinemia 22122052 "Among deregulated miRNAs, miR-155 and miR-9* play a pivotal role in the pathogenesis of this disease." other hsa-mir-9 Waldenstrom Macroglobulinemia 22122052 "Among deregulated miRNAs, miR-155 and miR-9* play a pivotal role in the pathogenesis of this disease." other hsa-mir-210 Ischemic Diseases [unspecific] 22123256 Upregulation of microRNA-210 regulates renal angiogenesis mediated by activation of VEGF signaling pathway under ischemia/perfusion injury in vivo and in vitro. other hsa-let-7a Neoplasms [unspecific] 22129484 "The let-7 family of microRNAs has cancer suppressor activity, and recent evidence suggests that markedly reduced levels of let-7 are not only a typical feature of cancer stem cells, but may be largely responsible for cancer stemness." other hsa-let-7b Neoplasms [unspecific] 22129484 "The let-7 family of microRNAs has cancer suppressor activity, and recent evidence suggests that markedly reduced levels of let-7 are not only a typical feature of cancer stem cells, but may be largely responsible for cancer stemness." other hsa-let-7c Neoplasms [unspecific] 22129484 "The let-7 family of microRNAs has cancer suppressor activity, and recent evidence suggests that markedly reduced levels of let-7 are not only a typical feature of cancer stem cells, but may be largely responsible for cancer stemness." other hsa-let-7d Neoplasms [unspecific] 22129484 "The let-7 family of microRNAs has cancer suppressor activity, and recent evidence suggests that markedly reduced levels of let-7 are not only a typical feature of cancer stem cells, but may be largely responsible for cancer stemness." other hsa-let-7e Neoplasms [unspecific] 22129484 "The let-7 family of microRNAs has cancer suppressor activity, and recent evidence suggests that markedly reduced levels of let-7 are not only a typical feature of cancer stem cells, but may be largely responsible for cancer stemness." other hsa-let-7f Neoplasms [unspecific] 22129484 "The let-7 family of microRNAs has cancer suppressor activity, and recent evidence suggests that markedly reduced levels of let-7 are not only a typical feature of cancer stem cells, but may be largely responsible for cancer stemness." other hsa-let-7g Neoplasms [unspecific] 22129484 "The let-7 family of microRNAs has cancer suppressor activity, and recent evidence suggests that markedly reduced levels of let-7 are not only a typical feature of cancer stem cells, but may be largely responsible for cancer stemness." other hsa-let-7i Neoplasms [unspecific] 22129484 "The let-7 family of microRNAs has cancer suppressor activity, and recent evidence suggests that markedly reduced levels of let-7 are not only a typical feature of cancer stem cells, but may be largely responsible for cancer stemness." other hsa-mir-202 Neoplasms [unspecific] 22129484 "The let-7 family of microRNAs has cancer suppressor activity, and recent evidence suggests that markedly reduced levels of let-7 are not only a typical feature of cancer stem cells, but may be largely responsible for cancer stemness." other hsa-mir-98 Neoplasms [unspecific] 22129484 "The let-7 family of microRNAs has cancer suppressor activity, and recent evidence suggests that markedly reduced levels of let-7 are not only a typical feature of cancer stem cells, but may be largely responsible for cancer stemness." other hsa-mir-182 Medulloblastoma 22134538 MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma. other hsa-mir-143 Cardiovascular Diseases [unspecific] 22135162 "MicroRNAs are critical for vascular smooth muscle cell differentiation and phenotype regulation, and miR-143 and miR-145 play a particularly important role in this respect." other hsa-mir-145 Cardiovascular Diseases [unspecific] 22135162 "MicroRNAs are critical for vascular smooth muscle cell differentiation and phenotype regulation, and miR-143 and miR-145 play a particularly important role in this respect." other hsa-mir-135a-1 Glioma 22139076 MiR-135a functions as a selective killer of malignant glioma. other hsa-mir-135a-2 Glioma 22139076 MiR-135a functions as a selective killer of malignant glioma. other hsa-mir-7-1 Gastric Neoplasms 22139078 Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells. other hsa-mir-7-2 Gastric Neoplasms 22139078 Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells. other hsa-mir-7-3 Gastric Neoplasms 22139078 Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells. other hsa-mir-30c-1 Endometrial Neoplasms 22139444 Endometrial Neoplasms other hsa-mir-30c-2 Endometrial Neoplasms 22139444 Endometrial Neoplasms other hsa-mir-494 Lung Neoplasms 22151897 MicroRNA-494 suppresses cell proliferation and induces senescence in A549 lung cancer cells. other hsa-mir-30e Glioma 22156201 MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-§Ø¨mB/I§Ø¨mB§Ø©ãnegative feedback loop. other hsa-mir-1301 "Carcinoma, Hepatocellular" 22159405 microRNA-1301-mediated inhibition of tumorigenesis. other hsa-mir-96 "Carcinoma, Hepatocellular" 22160187 Suppression of microRNA-96 expression inhibits the invasion of hepatocellular carcinoma cells. other hsa-mir-17 Hypertension 22161164 Inhibition of microRNA-17 Improves Lung and Heart Function in Experimental Pulmonary Hypertension. other hsa-mir-1-1 Heart Failure 22163007 MicroRNA-1 and -133 Increase Arrhythmogenesis in Heart Failure by Dissociating Phosphatase Activity from RyR2 Complex. other hsa-mir-1-2 Heart Failure 22163007 MicroRNA-1 and -133 Increase Arrhythmogenesis in Heart Failure by Dissociating Phosphatase Activity from RyR2 Complex. other hsa-mir-133a-1 Heart Failure 22163007 MicroRNA-1 and -133 Increase Arrhythmogenesis in Heart Failure by Dissociating Phosphatase Activity from RyR2 Complex. other hsa-mir-133a-2 Heart Failure 22163007 MicroRNA-1 and -133 Increase Arrhythmogenesis in Heart Failure by Dissociating Phosphatase Activity from RyR2 Complex. other hsa-mir-133b Heart Failure 22163007 MicroRNA-1 and -133 Increase Arrhythmogenesis in Heart Failure by Dissociating Phosphatase Activity from RyR2 Complex. other hsa-mir-29a Biliary Atresia 22167021 MicroRNA Profiling Identifies miR-29 as a Regulator of Disease-Associated Pathways in Experimental Biliary Atresia. other hsa-mir-29b-1 Biliary Atresia 22167021 MicroRNA Profiling Identifies miR-29 as a Regulator of Disease-Associated Pathways in Experimental Biliary Atresia. other hsa-let-7a Gastrointestinal Neoplasms 22168593 "The aim of the present review was to describe the mechanisms of several known miR, summarize recent studies on oncogenic miR (e.g. miR-21, miR-106a and miR-17), tumor suppressor miR (e.g. miR-101, miR-181, miR-449, miR-486, let-7a) and controversial roles of miR (e.g. miR-107, miR-126) for gastric cancer." other hsa-mir-101 Gastrointestinal Neoplasms 22168593 "The aim of the present review was to describe the mechanisms of several known miR, summarize recent studies on oncogenic miR (e.g. miR-21, miR-106a and miR-17), tumor suppressor miR (e.g. miR-101, miR-181, miR-449, miR-486, let-7a) and controversial roles of miR (e.g. miR-107, miR-126) for gastric cancer." other hsa-mir-106a Gastrointestinal Neoplasms 22168593 "The aim of the present review was to describe the mechanisms of several known miR, summarize recent studies on oncogenic miR (e.g. miR-21, miR-106a and miR-17), tumor suppressor miR (e.g. miR-101, miR-181, miR-449, miR-486, let-7a) and controversial roles of miR (e.g. miR-107, miR-126) for gastric cancer." other hsa-mir-107 Gastrointestinal Neoplasms 22168593 "The aim of the present review was to describe the mechanisms of several known miR, summarize recent studies on oncogenic miR (e.g. miR-21, miR-106a and miR-17), tumor suppressor miR (e.g. miR-101, miR-181, miR-449, miR-486, let-7a) and controversial roles of miR (e.g. miR-107, miR-126) for gastric cancer." other hsa-mir-126 Gastrointestinal Neoplasms 22168593 "The aim of the present review was to describe the mechanisms of several known miR, summarize recent studies on oncogenic miR (e.g. miR-21, miR-106a and miR-17), tumor suppressor miR (e.g. miR-101, miR-181, miR-449, miR-486, let-7a) and controversial roles of miR (e.g. miR-107, miR-126) for gastric cancer." other hsa-mir-17 Gastrointestinal Neoplasms 22168593 "The aim of the present review was to describe the mechanisms of several known miR, summarize recent studies on oncogenic miR (e.g. miR-21, miR-106a and miR-17), tumor suppressor miR (e.g. miR-101, miR-181, miR-449, miR-486, let-7a) and controversial roles of miR (e.g. miR-107, miR-126) for gastric cancer." other hsa-mir-181 Gastrointestinal Neoplasms 22168593 "The aim of the present review was to describe the mechanisms of several known miR, summarize recent studies on oncogenic miR (e.g. miR-21, miR-106a and miR-17), tumor suppressor miR (e.g. miR-101, miR-181, miR-449, miR-486, let-7a) and controversial roles of miR (e.g. miR-107, miR-126) for gastric cancer." other hsa-mir-21 Gastrointestinal Neoplasms 22168593 "The aim of the present review was to describe the mechanisms of several known miR, summarize recent studies on oncogenic miR (e.g. miR-21, miR-106a and miR-17), tumor suppressor miR (e.g. miR-101, miR-181, miR-449, miR-486, let-7a) and controversial roles of miR (e.g. miR-107, miR-126) for gastric cancer." other hsa-mir-449 Gastrointestinal Neoplasms 22168593 "The aim of the present review was to describe the mechanisms of several known miR, summarize recent studies on oncogenic miR (e.g. miR-21, miR-106a and miR-17), tumor suppressor miR (e.g. miR-101, miR-181, miR-449, miR-486, let-7a) and controversial roles of miR (e.g. miR-107, miR-126) for gastric cancer." other hsa-mir-486 Gastrointestinal Neoplasms 22168593 "The aim of the present review was to describe the mechanisms of several known miR, summarize recent studies on oncogenic miR (e.g. miR-21, miR-106a and miR-17), tumor suppressor miR (e.g. miR-101, miR-181, miR-449, miR-486, let-7a) and controversial roles of miR (e.g. miR-107, miR-126) for gastric cancer." other hsa-mir-335 Glioma 22172575 MiR-335 is Required for Differentiation of Malignant Glioma Cells Induced by Activation of cAMP/PKA Pathway. other hsa-mir-574 Urinary Bladder Cancer 22179486 Novel oncogenic function of mesoderm development candidate 1 and its regulation by MiR-574-3p in bladder cancer cell lines. other hsa-mir-1-1 Colon Neoplasms 22179665 MIR-1 DOWNREGULATION COOPERATES WITH MACC1 IN PROMOTING MET OVEREXPRESSION IN HUMAN COLON CANCER. other hsa-mir-133b Urinary Bladder Cancer 22179829 MicroRNA-133b is a key promoter of cervical carcinoma development through the activation of the ERK and AKT1 pathways. other hsa-mir-21 Breast Neoplasms 22187223 Re-expression of miR-21 contributes to migration and invasion by inducing epithelial-mesenchymal transition consistent with cancer stem cell characteristics in MCF-7 cells. other hsa-mir-610 Gastric Neoplasms 22189055 MicroRNA-610 inhibits the migration and invasion of gastric cancer cells by suppressing the expression of vasodilator-stimulated phosphoprotein. other hsa-mir-122 Hepatitis C Virus Infection 22189820 "Here we show that HCV IRES-dependent translation efficiency in the hepatoma cell line Huh7 is highest during the G 0 and G 1 phases of the cell cycle but significantly drops during the S phase and even more in the G 2/M phase. The superimposed stimulation of HCV translation by ectopic miR-122 works best during the G 0, G 1 and G 2/M phases but is lower during the S phase. However, the levels of Ago2 protein do not substantially change during cell cycle phases, indicating that other cellular factors involved in HCV translation stimulation by miR-122 may be differentially expressed in different cell cycle phases. Moreover, the levels of endogenously expressed miR-122 in Huh7 cells are lowest in the S phase, indicating that the predominant G 0/G 1 state of non-dividing hepatocytes in the liver facilitates high expression of the HCV genome and stimulation by miR-122, with yet unknown factors involved in the differential extent of stimulation by miR-122." other hsa-mir-195 Heart Failure 22190509 "microRNA-195(miR-195) is an important member of the micro-15/16/195/424/497 family, and which is activated in multiple diseases, such as cancers, heart failure, and schizophrenia." other hsa-mir-195 Schizophrenia 22190509 "microRNA-195(miR-195) is an important member of the micro-15/16/195/424/497 family, and which is activated in multiple diseases, such as cancers, heart failure, and schizophrenia." other hsa-mir-34a Melanoma 22198089 "Our preliminary study suggests that miR-34a, although having a role in late tumorigenesis, does not contribute to the inherited susceptibility to cutaneous melanoma. " other hsa-mir-106a Colorectal Carcinoma 22202009 "miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks." other hsa-mir-181b-1 Colorectal Carcinoma 22202009 "miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks." other hsa-mir-181b-2 Colorectal Carcinoma 22202009 "miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks." other hsa-mir-203 Colorectal Carcinoma 22202009 "miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks." other hsa-mir-20a Colorectal Carcinoma 22202009 "miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks." other hsa-mir-21 Colorectal Carcinoma 22202009 "miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks." other hsa-mir-324 Colorectal Carcinoma 22202009 "miR-20a, miR-21, miR-106a, miR-181b, miR-203, and miR-324-5p were stable in colorectal cancer archival tissue blocks." other hsa-mir-451 Glioblastoma 22205943 "The model provides an explanation for the growth-invasion cycling patterns of glioma cells in response to high/low glucose uptake in microenvironment in vitro, and suggests new targets for drugs,associated with miR-451 upregulation." other hsa-mir-31 Gastric Neoplasms 22212233 PDCD4 expression inversely correlated with miR-21 levels in gastric cancers. other hsa-mir-520e "Carcinoma, Hepatocellular" 22212428 A novel tumor suppressor miRNA miR-520e contributes to suppression of hepatoma. other hsa-mir-21 Cholangiocarcinoma 22213145 "Based on our data, we conclude that Ars2 is overexpressed in human CCA and may be a diagnostic marker. Ars2 depletion increases PTEN and PDCD4 protein levels via the reduction of miR-21." other hsa-mir-125b-1 Melanoma 22213330 "Treatment with 5-Aza, but not with TSA, reduced the expression of miR-125b in the 1,25(OH)(2)D(3)-responsive and -resistant melanoma cell lines and in the NHM." other hsa-mir-125b-2 Melanoma 22213330 "Treatment with 5-Aza, but not with TSA, reduced the expression of miR-125b in the 1,25(OH)(2)D(3)-responsive and -resistant melanoma cell lines and in the NHM." other hsa-mir-27b Melanoma 22213330 "Treatment with 1,25(OH)(2)D(3) and/or epigenetic drugs (5-Aza, TSA) reduced the miR-27b expression in three out of four melanoma cell lines." other hsa-mir-21 "Muscular Dystrophy, Duchenne" 22213800 PAI-1-regulated miR-21 defines a novel age-associated fibrogenic pathway in muscular dystrophy. other hsa-mir-126 Cardiovascular Diseases [unspecific] 22215713 miRNA-126 levels were reduced in SHRs with an increase of 51% in phosphoinositol-3 kinase regulatory subunit 2 expression but normalized in SHR-Ts. other hsa-mir-26b Hypertrophy 22219180 GATA4 expression is primarily regulated via a miR-26b-dependent post-transcriptional mechanism during cardiac hypertrophy. other hsa-mir-21 Pituitary Adenoma 22222153 "We speculated the mechanism of miR-21 is involved in tumorigenesis, leading to improvements in therapies and prevention of metastasis." other hsa-mir-192 Diabetic Nephropathy 22223877 Inhibiting MicroRNA-192 Ameliorates Renal Fibrosis in Diabetic Nephropathy other hsa-mir-650 "Leukemia, Lymphocytic, Chronic, B-Cell" 22234685 MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia. other hsa-mir-34a Prostate Neoplasms 22235332 MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells. other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 22237007 "Increased miR-21 expression significantly increased the resistance of A549 cell to platinum, whereas reduced miR-21 decreased the resistance of A549/CDDP cell." other hsa-mir-133b Parkinson Disease 22245218 "miR-133b is deficient in the PD midbrain as well as in mouse models, and miR-34b/34c are decreased in several affected brain regions in PD and incidental Lewy body disease." other hsa-let-7c Pancreatic Neoplasms 22245693 "Metformin up-regulated the expression of miR-26a, miR-192 and let-7c in a dose-dependent manner." other hsa-mir-192 Pancreatic Neoplasms 22245693 "Metformin up-regulated the expression of miR-26a, miR-192 and let-7c in a dose-dependent manner." other hsa-mir-26a-1 Pancreatic Neoplasms 22245693 "Metformin up-regulated the expression of miR-26a, miR-192 and let-7c in a dose-dependent manner. Forced expression of miR-26a significantly inhibited cell proliferation, invasion, migration and increased cell apoptosis, whereas knockdown of miR-26a obtained the opposite effect." other hsa-mir-26a-2 Pancreatic Neoplasms 22245693 "Metformin up-regulated the expression of miR-26a, miR-192 and let-7c in a dose-dependent manner. Forced expression of miR-26a significantly inhibited cell proliferation, invasion, migration and increased cell apoptosis, whereas knockdown of miR-26a obtained the opposite effect." other hsa-mir-155 Breast Neoplasms 22245916 "Up-regulated miR-155 expression was associated with lymph node positivity (P=0.034), higher proliferation index (Ki-67 >10%) (P=0.019) and advanced breast cancer TNM clinical stage (P=0.002)." other hsa-mir-100 "Carcinoma, Hepatocellular" 22249248 Sequential analysis of multistage hepatocarcinogenesis reveals that miR-100 and PLK1 dysregulation is an early event maintained along tumor progression. other hsa-mir-155 Myelodysplastic Syndromes 22249254 Loss of SHIP-1 protein expression in high-risk myelodysplastic syndromes is associated with miR-210 and miR-155. other hsa-mir-210 Myelodysplastic Syndromes 22249254 Loss of SHIP-1 protein expression in high-risk myelodysplastic syndromes is associated with miR-210 and miR-155. other hsa-mir-21 "Carcinoma, Oral" 22249446 miR-21 inhibitor sensitizes human OSCC(oral squamous cell carcinoma) cells to cisplatin. other hsa-mir-196a-1 Gastrointestinal Neoplasms 22258453 Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors. other hsa-mir-196a-2 Gastrointestinal Neoplasms 22258453 Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors. other hsa-mir-143 Breast Neoplasms 22260523 "E2 significantly induced bcl-2, cyclin D1 and survivin expression by suppressing the levels of a panel of miRNAs (miR-16, miR-143, miR-203) in MCF-7 cells." other hsa-mir-16-1 Breast Neoplasms 22260523 "E2 significantly induced bcl-2, cyclin D1 and survivin expression by suppressing the levels of a panel of miRNAs (miR-16, miR-143, miR-203) in MCF-7 cells." other hsa-mir-16-2 Breast Neoplasms 22260523 "E2 significantly induced bcl-2, cyclin D1 and survivin expression by suppressing the levels of a panel of miRNAs (miR-16, miR-143, miR-203) in MCF-7 cells." other hsa-mir-203 Breast Neoplasms 22260523 "E2 significantly induced bcl-2, cyclin D1 and survivin expression by suppressing the levels of a panel of miRNAs (miR-16, miR-143, miR-203) in MCF-7 cells." other hsa-mir-24-1 Myocardial Infarction 22260784 MicroRNA-24 Regulates Cardiac Fibrosis after Myocardial Infarction. other hsa-mir-24-2 Myocardial Infarction 22260784 MicroRNA-24 Regulates Cardiac Fibrosis after Myocardial Infarction. other hsa-mir-125b-1 Neoplasms [unspecific] 22268450 Camptothecin Induces Apoptosis in Cancer Cells via miR-125b Mediated Mitochondrial Pathways. other hsa-mir-125b-2 Neoplasms [unspecific] 22268450 Camptothecin Induces Apoptosis in Cancer Cells via miR-125b Mediated Mitochondrial Pathways. other hsa-mir-155 Lymphoma 22268450 Epstein-Barr virus latent membrane protein-1 protects B-cell lymphoma from rituximab-induced apoptosis through miR-155-mediated Akt activation and up-regulation of Mcl-1. other hsa-mir-145 Glioma 22269208 Over-expression of miR-145 enhances the effectiveness of HSVtk gene therapy for malignant glioma. other hsa-mir-140 Osteoarthritis 22273691 Expression of miRNA-140 and MMP-13 was elevated in IL-1¦Â-stimulated C28/I2 cells. other hsa-mir-33a Atherosclerosis 22274626 microRNA-33a and b (miR-33a/b) were discovered as key regulators of metabolic programs including cholesterol and fatty acid homeostasis. other hsa-mir-33b Atherosclerosis 22274626 microRNA-33a and b (miR-33a/b) were discovered as key regulators of metabolic programs including cholesterol and fatty acid homeostasis. other hsa-mir-21 Colorectal Carcinoma 22281474 "Aging and DMH are associated with increases in CSLC biomarkers and miR21, each of which have been linked to colorectal cancer." other hsa-mir-199a-1 Leukemia 22285730 Low microRNA-199a expression in human amniotic epithelial cell feeder layers maintains human-induced pluripotent stem cell pluripotency via increased leukemia inhibitory factor expression. other hsa-mir-199a-2 Leukemia 22285730 Low microRNA-199a expression in human amniotic epithelial cell feeder layers maintains human-induced pluripotent stem cell pluripotency via increased leukemia inhibitory factor expression. other hsa-mir-145 Urinary Bladder Cancer 22287315 Glucocorticoid regulation of a novel HPV E6-p53-miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells. other hsa-mir-200b Crohn Disease 22294131 miR-200b is involved in intestinal fibrosis of Crohn's disease. other hsa-mir-106a "Carcinoma, Lung, Non-Small-Cell" 22295063 "The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r=0.17, P=0.002), though most prominent in the subgroup with nodal metastasis (r=0.34, P<0.001)." other hsa-mir-126 "Carcinoma, Lung, Non-Small-Cell" 22295063 "The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r=0.17, P=0.002), though most prominent in the subgroup with nodal metastasis (r=0.34, P<0.001)." other hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 22295063 "The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r=0.17, P=0.002), though most prominent in the subgroup with nodal metastasis (r=0.34, P<0.001)." other hsa-mir-182 "Carcinoma, Lung, Non-Small-Cell" 22295063 "The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r=0.17, P=0.002), though most prominent in the subgroup with nodal metastasis (r=0.34, P<0.001)." other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 22295063 "The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r=0.17, P=0.002), though most prominent in the subgroup with nodal metastasis (r=0.34, P<0.001)." other hsa-mir-210 "Carcinoma, Lung, Non-Small-Cell" 22295063 "The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r=0.17, P=0.002), though most prominent in the subgroup with nodal metastasis (r=0.34, P<0.001)." other hsa-mir-424 "Carcinoma, Lung, Non-Small-Cell" 22295063 "The significantly altered angiogenesis-related miRs of high interest were miR-21, miR-106a, miR-126, miR-155, miR-182, miR-210 and miR-424. miR-155 correlated significantly with fibroblast growth factor 2 (FGF2) in the total cohort (r=0.17, P=0.002), though most prominent in the subgroup with nodal metastasis (r=0.34, P<0.001)." other hsa-let-7a-1 Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. other hsa-let-7a-2 Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. other hsa-let-7a-3 Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. other hsa-let-7b Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. other hsa-let-7c Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. other hsa-let-7d Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. other hsa-let-7e Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. other hsa-let-7f-1 Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. other hsa-let-7f-2 Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. other hsa-let-7g Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. other hsa-let-7i Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. other hsa-mir-31 Lung Neoplasms 22301433 Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells. other hsa-mir-31 Barrett Esophagus 22302717 "The authors propose miR-31 and -375 as novel candidate microRNAs specifically associated with early- and late-stage malignant progression, respectively, in Barrett's esophagus." other hsa-mir-375 Barrett Esophagus 22302717 "The authors propose miR-31 and -375 as novel candidate microRNAs specifically associated with early- and late-stage malignant progression, respectively, in Barrett's esophagus." other hsa-mir-181c Fanconi Anemia 22310912 Downregulated expression of hsa-miR-181c in Fanconi anemia patients: implications in TNF§Ø©ãregulation and proliferation of hematopoietic progenitor cells. other hsa-mir-146a Pancreatic Neoplasms 22311263 Aberrant elevated microRNA-146a in dendritic cells (DC) induced by human pancreatic cancer cell line BxPC-3-conditioned medium inhibits DC maturation and activation. other hsa-mir-125a Gastric Neoplasms 22322911 "Low expression levels of miR-125a-3p were associated with indicators of enhanced malignant potential such as tumor size (p=0.0002), tumor invasion (p=0.0149), lymph node metastasis (p=0.018), liver metastasis (p=0.016), peritoneal dissemination (p=0.03), advanced clinical stage (p=0.0037) and poor prognosis (p=0.0083)." other hsa-mir-10b Colorectal Carcinoma 22322955 MicroRNA-10b is a Prognostic Indicator in Colorectal Cancer and Confers Resistance to the Chemotherapeutic Agent 5-Fluorouracil in Colorectal Cancer Cells. other hsa-mir-1 Heart Failure 22326846 These findings demonstrate the importance of miR-1 in cardiac function and in the pathogenesis of heart failure via Sorcin-dependent calcium homeostasis. other hsa-mir-22 Colon Neoplasms 22328083 "MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells." other hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 22331473 "miR-145* inhibits cell invasion and metastasis, and is associated with brain metastasis." other hsa-mir-15a Breast Neoplasms 22335947 "The expression level of miR-15a in MCF-7 cells was lower than that in the MCF-10A cells (0.253:1, P < 0.0001). The expression of MiR-15a was significantly inhibited by Bcl-2 (P < 0.05)." other hsa-mir-199a-2 Sezary Disease 22336940 Deep-Sequencing Analysis Reveals that the miR-199a2/214 Cluster within DNM3os Represents the Vast Majority of Aberrantly Expressed MicroRNAs in S§Ú§Øzary Syndrome. other hsa-mir-214 Sezary Disease 22336940 Deep-Sequencing Analysis Reveals that the miR-199a2/214 Cluster within DNM3os Represents the Vast Majority of Aberrantly Expressed MicroRNAs in S§Ú§Øzary Syndrome. other hsa-mir-122 Hepatitis C Virus Infection 22342424 Suppression of hepatitis C virus replicon by adenovirus vector-mediated expression of tough decoy RNA against miR-122a. other hsa-mir-1-1 Colorectal Carcinoma 22343615 MicroRNA profiling in colorectal cancer highlights miR-1 involvement in MET-dependent proliferation. other hsa-mir-31 Pancreatic Neoplasms 22344632 Both inhibition and enhanced expression of miR-31 lead to reduced migration and invasion of pancreatic cancer cells. other hsa-mir-21 Renal Fibrosis 22344686 MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways. other hsa-mir-21 Kidney Neoplasms 22347428 Up-Regulation of MicroRNA-21 Correlates with Lower Kidney Cancer Survival. other hsa-mir-197 Thyroid Neoplasms 22351693 "A SVM model with 4 miRNAs (miR-222, miR-328, miR-197 and miR-21) was initially estimated to have 86% predictive accuracy using cross-validation to differentiate Malignant from Benign." other hsa-mir-21 Thyroid Neoplasms 22351693 "A SVM model with 4 miRNAs (miR-222, miR-328, miR-197 and miR-21) was initially estimated to have 86% predictive accuracy using cross-validation to differentiate Malignant from Benign." other hsa-mir-222 Thyroid Neoplasms 22351693 "A SVM model with 4 miRNAs (miR-222, miR-328, miR-197 and miR-21) was initially estimated to have 86% predictive accuracy using cross-validation to differentiate Malignant from Benign." other hsa-mir-328 Thyroid Neoplasms 22351693 "A SVM model with 4 miRNAs (miR-222, miR-328, miR-197 and miR-21) was initially estimated to have 86% predictive accuracy using cross-validation to differentiate Malignant from Benign." other hsa-mir-128b Lung Neoplasms 22352917 "Among them, 11 miRNAs including miR-7 and miR-128b were confirmed by published experimental data or literatures." other hsa-mir-7 Lung Neoplasms 22352917 "Among them, 11 miRNAs including miR-7 and miR-128b were confirmed by published experimental data or literatures." other hsa-mir-101-1 Colon Neoplasms 22353936 MicroRNA-101 (miR-101) post-transcriptionally regulates the expression of EP4 receptor in colon cancers. other hsa-mir-101-2 Colon Neoplasms 22353936 MicroRNA-101 (miR-101) post-transcriptionally regulates the expression of EP4 receptor in colon cancers. other hsa-mir-21 "Aortic Aneurysm, Abdominal" 22357537 MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion. other hsa-mir-196a-1 Keloid 22358059 miR-196a Downregulation Increases the Expression of Type I and III Collagens in Keloid Fibroblasts. other hsa-mir-196a-2 Keloid 22358059 miR-196a Downregulation Increases the Expression of Type I and III Collagens in Keloid Fibroblasts. other hsa-mir-941-1 "Colitis, Ulcerative" 22359580 UC susceptibility other hsa-mir-941-3 "Colitis, Ulcerative" 22359580 UC susceptibility other hsa-mir-941-4 "Colitis, Ulcerative" 22359580 UC susceptibility other hsa-mir-1-1 Heart Failure 22362515 SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway. other hsa-mir-1-2 Heart Failure 22362515 SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway. other hsa-mir-132 Inflammation 22362752 we propose an outline of the current knowledge about miR-132 and miR-212 functions in neurons and immune cells other hsa-mir-212 Inflammation 22362752 we propose an outline of the current knowledge about miR-132 and miR-212 functions in neurons and immune cells other hsa-mir-148b Glomerulonephritis 22362909 Abnormal miR-148b Expression Promotes Aberrant Glycosylation of IgA1 in IgA Nephropathy. other hsa-mir-146a Prion Diseases 22363497 MicroRNA 146a (miR-146a) Is Over-Expressed during Prion Disease and Modulates the Innate Immune Response and the Microglial Activation State. other hsa-mir-200c Breast Neoplasms 22364742 IL6-Mediated Suppression of miR-200c Directs Constitutive Activation of Inflammatory Signaling Circuit Driving Transformation and Tumorigenesis. other hsa-mir-142 Hypertrophy 22367739 Repression of miR-142 by p300 and MAPK is required for survival signaling via gp130 during adaptive hypertrophy. other hsa-mir-124-1 "Carcinoma, Lung, Non-Small-Cell" 22370637 "The authors found a number of miRNAs (miR-17, miR-135, miR-520, miR-124-1, and miR-34c) that may rescue cell viability from caspase-8 activation." other hsa-mir-135a-1 "Carcinoma, Lung, Non-Small-Cell" 22370637 "The authors found a number of miRNAs (miR-17, miR-135, miR-520, miR-124-1, and miR-34c) that may rescue cell viability from caspase-8 activation." other hsa-mir-135a-2 "Carcinoma, Lung, Non-Small-Cell" 22370637 "The authors found a number of miRNAs (miR-17, miR-135, miR-520, miR-124-1, and miR-34c) that may rescue cell viability from caspase-8 activation." other hsa-mir-135b "Carcinoma, Lung, Non-Small-Cell" 22370637 "The authors found a number of miRNAs (miR-17, miR-135, miR-520, miR-124-1, and miR-34c) that may rescue cell viability from caspase-8 activation." other hsa-mir-17 "Carcinoma, Lung, Non-Small-Cell" 22370637 "The authors found a number of miRNAs (miR-17, miR-135, miR-520, miR-124-1, and miR-34c) that may rescue cell viability from caspase-8 activation." other hsa-mir-520a "Carcinoma, Lung, Non-Small-Cell" 22370637 "The authors found a number of miRNAs (miR-17, miR-135, miR-520, miR-124-1, and miR-34c) that may rescue cell viability from caspase-8 activation." other hsa-mir-520b "Carcinoma, Lung, Non-Small-Cell" 22370637 "The authors found a number of miRNAs (miR-17, miR-135, miR-520, miR-124-1, and miR-34c) that may rescue cell viability from caspase-8 activation." other hsa-mir-520c "Carcinoma, Lung, Non-Small-Cell" 22370637 "The authors found a number of miRNAs (miR-17, miR-135, miR-520, miR-124-1, and miR-34c) that may rescue cell viability from caspase-8 activation." other hsa-mir-520d "Carcinoma, Lung, Non-Small-Cell" 22370637 "The authors found a number of miRNAs (miR-17, miR-135, miR-520, miR-124-1, and miR-34c) that may rescue cell viability from caspase-8 activation." other hsa-mir-520e "Carcinoma, Lung, Non-Small-Cell" 22370637 "The authors found a number of miRNAs (miR-17, miR-135, miR-520, miR-124-1, and miR-34c) that may rescue cell viability from caspase-8 activation." other hsa-mir-152 Atherosclerosis 22370758 Co-expression in plaque tissue and classical monocytes. other hsa-mir-422a Atherosclerosis 22370758 Co-expression in plaque tissue and non-classical monocytes. other hsa-mir-99b Atherosclerosis 22370758 Co-expression in plaque tissue and classical monocytes. other hsa-mir-146a Inflammation 22371089 miR-146a and miR-147 are involved in the resolution phase of inflammation. other hsa-mir-147 Inflammation 22371089 miR-146a and miR-147 are involved in the resolution phase of inflammation. other hsa-mir-21 Hypertension 22371328 MicroRNA-21 Integrates Pathogenic Signaling to Control Pulmonary Hypertension other hsa-mir-493 Colon Neoplasms 22373578 miR-493 induction during carcinogenesis blocks metastatic settlement of colon cancer cells in liver. other hsa-mir-143 Atherosclerosis 22373869 Secreted miRNAs (miR-143/145) suppress atherogenesis. other hsa-mir-145 Atherosclerosis 22373869 Secreted miRNAs (miR-143/145) suppress atherogenesis. other hsa-mir-146a Rheumatoid Arthritis 22374446 "In 2008, miR-146a and miR-155 were reported to be involved in the pathology of rheumatoid arthritis." other hsa-mir-155 Rheumatoid Arthritis 22374446 "In 2008, miR-146a and miR-155 were reported to be involved in the pathology of rheumatoid arthritis." other hsa-mir-145 "Carcinoma, Hepatocellular" 22378186 Tumorigenicity of cancer stem-like cells derived from hepatocarcinoma is regulated by microRNA-145. other hsa-mir-26a-1 Breast Neoplasms 22384020 Trastuzumab Produces Therapeutic Actions by Upregulating miR-26a and miR-30b in Breast Cancer Cells. other hsa-mir-26a-2 Breast Neoplasms 22384020 Trastuzumab Produces Therapeutic Actions by Upregulating miR-26a and miR-30b in Breast Cancer Cells. other hsa-mir-30b Breast Neoplasms 22384020 Trastuzumab Produces Therapeutic Actions by Upregulating miR-26a and miR-30b in Breast Cancer Cells. other hsa-mir-302b Colon Neoplasms 22384170 Ascl2 Knockdown Results in Tumor Growth Arrest by miRNA-302b-Related Inhibition of Colon Cancer Progenitor Cells. other hsa-let-7b Hepatitis C Virus Infection 22391672 Let-7b is a novel regulator of hepatitis C virus replication. other hsa-mir-146b Obesity 22393448 Decrease of miR-146b-5p in Monocytes during Obesity Is Associated with Loss of the Anti-Inflammatory but Not Insulin Signaling Action of Adiponectin. other hsa-mir-376b Myocardial Ischemic-Reperfusion Injury 22396777 M(3) Subtype of Muscarinic Acetylcholine Receptor Promotes Cardioprotection via the Suppression of miR-376b-5p. other hsa-mir-29b-1 "Carcinoma, Lung, Non-Small-Cell" 22399498 increased after necitumumab in combination with cisplatin/gemcitabine other hsa-mir-29b-2 "Carcinoma, Lung, Non-Small-Cell" 22399498 increased after necitumumab in combination with cisplatin/gemcitabine other hsa-mir-29b-1 Prostate Neoplasms 22402125 MicroRNA-29b Suppresses Prostate Cancer Metastasis by Regulating Epithelial-Mesenchymal Transition Signaling. other hsa-mir-29b-2 Prostate Neoplasms 22402125 MicroRNA-29b Suppresses Prostate Cancer Metastasis by Regulating Epithelial-Mesenchymal Transition Signaling. other hsa-mir-133a-1 Atrial Fibrillation 22407060 both miR-133 and miR-30 play an important role in controlling structural changes in chronic AF other hsa-mir-133a-2 Atrial Fibrillation 22407060 both miR-133 and miR-30 play an important role in controlling structural changes in chronic AF other hsa-mir-133b Atrial Fibrillation 22407060 both miR-133 and miR-30 play an important role in controlling structural changes in chronic AF other hsa-mir-30a Atrial Fibrillation 22407060 both miR-133 and miR-30 play an important role in controlling structural changes in chronic AF other hsa-mir-30b Atrial Fibrillation 22407060 both miR-133 and miR-30 play an important role in controlling structural changes in chronic AF other hsa-mir-30c-1 Atrial Fibrillation 22407060 both miR-133 and miR-30 play an important role in controlling structural changes in chronic AF other hsa-mir-30c-2 Atrial Fibrillation 22407060 both miR-133 and miR-30 play an important role in controlling structural changes in chronic AF other hsa-mir-30d Atrial Fibrillation 22407060 both miR-133 and miR-30 play an important role in controlling structural changes in chronic AF other hsa-mir-126 Inflammation 22419694 MicroRNA-126 contributes to renal microvascular heterogeneity of VCAM-1 protein expression in acute inflammation. other hsa-mir-223 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 22424712 Notch-mediated repression of miR-223 contributes to IGF1R regulation in T-ALL. other hsa-mir-145 "Carcinoma, Hepatocellular" 22431718 MiR-145 modulates multiple components of the insulin-like growth factor pathway in hepatocellular carcinoma. other hsa-mir-192 "Carcinoma, Hepatocellular" 22433310 HBx gene down-regulates miR-192 expression and inhibits apoptosis of human hepatoma cell line HepG2. other hsa-mir-103 Metabolic Syndrome 22436747 "Other metabolic miRNAs, such as miR-103 and miR-107, regulate insulin and glucose homeostasis, whereas miRNAs such as miR-34a are emerging as key regulators of hepatic lipid homeostasis." other hsa-mir-107 Metabolic Syndrome 22436747 "Other metabolic miRNAs, such as miR-103 and miR-107, regulate insulin and glucose homeostasis, whereas miRNAs such as miR-34a are emerging as key regulators of hepatic lipid homeostasis." other hsa-mir-33a Metabolic Syndrome 22436747 "miR-33a and miR-33b have a crucial role in controlling cholesterol and lipid metabolism in concert with their host genes, the sterol-regulatory element-binding protein (SREBP) transcription factors." other hsa-mir-33b Metabolic Syndrome 22436747 "miR-33a and miR-33b have a crucial role in controlling cholesterol and lipid metabolism in concert with their host genes, the sterol-regulatory element-binding protein (SREBP) transcription factors." other hsa-mir-34a Metabolic Syndrome 22436747 "Other metabolic miRNAs, such as miR-103 and miR-107, regulate insulin and glucose homeostasis, whereas miRNAs such as miR-34a are emerging as key regulators of hepatic lipid homeostasis." other hsa-mir-193a Prostate Neoplasms 22438885 miR-193a-3p and miRPlus-E1245 observed to be specific to XMRV infection in all 4 cell types (Two prostate cell lines (LNCaP and DU145) and two primary cells). other hsa-mir-34b Breast Neoplasms 22439831 "MiR-34b is associated with clinical outcome in triple-negative breast cancer patients.Expression levels of miR-34b significantly correlate with disease free survival (DFS) (p = 0.0020, log-rank test) and overall survival (OS) (p = 0.0008, log-rank test) of TNBC patients." other hsa-mir-421 "Carcinoma, Hepatocellular" 22446874 Downregulation of Human Farnesoid X Receptor by miR-421 Promotes Proliferation and Migration of Hepatocellular Carcinoma Cells. other hsa-mir-25 Esophageal Neoplasms 22450326 MicroRNA-25 promotes cell migration and invasion in esophageal squamous cell carcinoma. other hsa-mir-20a Hypertension 22450430 AntagomiR directed against miR-20a restores functional BMPR2 signalling and prevents vascular remodelling in hypoxia-induced pulmonary hypertension. other hsa-let-7c Influenza 22452878 Cellular MicroRNA let-7c Inhibits M1 Protein Expression of the H1N1 Influenza A Virus in Infected Human Lung Epithelial Cells. other hsa-mir-146a Neoplasms [unspecific] 22453030 In this review we focus on recent progress in analyzing the functional role of miR-146a in the control of normal and malignant hematopoiesis. other hsa-mir-372 Colorectal Carcinoma 22456107 MicroRNA-372 Is Associated with Poor Prognosis in Colorectal Cancer. other hsa-mir-125b Inflammation 22456625 "Targets of miR-125b include key proteins regulating apoptosis, innate immunity, inflammation and hematopoietic differentiation." other hsa-mir-34a Osteosarcoma 22457788 MicroRNA-34a Inhibits the Proliferation and Metastasis of Osteosarcoma Cells Both In Vitro and In Vivo. other hsa-mir-29a Liver Diseases [unspecific] 22469499 Hepatic miR-29ab1 expression modulates chronic hepatic injury. other hsa-mir-29b-1 Liver Diseases [unspecific] 22469499 Hepatic miR-29ab1 expression modulates chronic hepatic injury. other hsa-mir-29b-2 Liver Diseases [unspecific] 22469499 Hepatic miR-29ab1 expression modulates chronic hepatic injury. other hsa-mir-106a "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-143 "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-145 "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-15a "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-16-1 "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-16-2 "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-18b "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-195 "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-19b-2 "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-20b "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-363 "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-497 "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-92a-2 "Squamous Cell Carcinoma, Cerevial" 22472886 "The miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145 and the miR-106-363 cluster appear to be important within the known HPV pathogenesis." other hsa-mir-103a-1 Pancreatic Neoplasms 22479426 "The driving miRNAs were miR-103, miR-23a and miR-15b in pancreatic cancers." other hsa-mir-103a-2 Pancreatic Neoplasms 22479426 "The driving miRNAs were miR-103, miR-23a and miR-15b in pancreatic cancers." other hsa-mir-103b-1 Pancreatic Neoplasms 22479426 "The driving miRNAs were miR-103, miR-23a and miR-15b in pancreatic cancers." other hsa-mir-103b-2 Pancreatic Neoplasms 22479426 "The driving miRNAs were miR-103, miR-23a and miR-15b in pancreatic cancers." other hsa-mir-1246 Colorectal Carcinoma 22479426 "The driving miRNAs were miR-195, miR-1280, miR-140-3p and miR-1246 in colorectal tumors." other hsa-mir-1280 Colorectal Carcinoma 22479426 "The driving miRNAs were miR-195, miR-1280, miR-140-3p and miR-1246 in colorectal tumors." other hsa-mir-140 Colorectal Carcinoma 22479426 "The driving miRNAs were miR-195, miR-1280, miR-140-3p and miR-1246 in colorectal tumors." other hsa-mir-15b Pancreatic Neoplasms 22479426 "The driving miRNAs were miR-103, miR-23a and miR-15b in pancreatic cancers." other hsa-mir-195 Colorectal Carcinoma 22479426 "The driving miRNAs were miR-195, miR-1280, miR-140-3p and miR-1246 in colorectal tumors." other hsa-mir-23a Pancreatic Neoplasms 22479426 "The driving miRNAs were miR-103, miR-23a and miR-15b in pancreatic cancers." other hsa-mir-92a Breast Neoplasms 22482439 We found that miR-221 levels are prognostic in breast cancer illustrating the high-throughput method and confirming that miRNAs can be valuable biomarkers in cancer. other hsa-mir-122 "Diabetes Mellitus, Type 2" 22488426 "Recent studies have shown key roles for miR-33 and miR-122 in regulation of lipid metabolism, and further evidence implicates miR-370 in regulation of miR-122." other hsa-mir-33 "Diabetes Mellitus, Type 2" 22488426 "Recent studies have shown key roles for miR-33 and miR-122 in regulation of lipid metabolism, and further evidence implicates miR-370 in regulation of miR-122." other hsa-mir-370 "Diabetes Mellitus, Type 2" 22488426 "Recent studies have shown key roles for miR-33 and miR-122 in regulation of lipid metabolism, and further evidence implicates miR-370 in regulation of miR-122." other hsa-mir-143 Glioblastoma 22490015 Serial selection for invasiveness increases expression of miR-143/miR-145 in glioblastoma cell lines. other hsa-mir-145 Glioblastoma 22490015 Serial selection for invasiveness increases expression of miR-143/miR-145 in glioblastoma cell lines. other hsa-mir-107 Head And Neck Neoplasms 22491216 Lipid-based Nanoparticle Delivery of Pre-miR-107 Inhibits the Tumorigenicity of Head and Neck Squamous Cell Carcinoma. other hsa-mir-193b "Carcinoma, Lung, Non-Small-Cell" 22491710 "MicroRNA-193b modulates proliferation, migration, and invasion of non-small cell lung cancer cells." other hsa-mir-127 "Carcinoma, Renal Cell" 22492545 "miR-127-3p, miR-145, and miR-126 are significantly correlated with relapse-free survival of nonmetastatic RCC patients." other hsa-mir-142 "Leukemia, Myeloid, Acute" 22493297 MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia. other hsa-mir-29a "Leukemia, Myeloid, Acute" 22493297 MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia. other hsa-mir-214 "Carcinoma, Lung, Non-Small-Cell" 22502680 MicroRNA-214 Regulates the Acquired Resistance to Gefitinib via the PTEN/AKT Pathway in EGFR-mutant Cell Lines. other hsa-mir-125 Leukemia 22504525 Here we discuss new findings concerning PU.1-controlled microRNAs and miR-125-regulated networks in normal and malignant myelopoiesis. other hsa-mir-181b Pancreatic Neoplasms 22504911 "miR-181b and miR-210 discriminatedPCa from normal individuals with receiver operating characteristic (ROC) curves and area under curve (AUC-ROC) of 0.745 and 0.772, respectively." other hsa-mir-143 Prostate Neoplasms 22505520 The authors experientially validated the miRNA-KLK interaction by transfecting miR-331-3p and miR-143 into a PCa cell line. other hsa-mir-331 Prostate Neoplasms 22505520 The authors experientially validated the miRNA-KLK interaction by transfecting miR-331-3p and miR-143 into a PCa cell line. other hsa-mir-375 Breast Neoplasms 22508479 Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer. other hsa-mir-34a "Lymphoma, Large B-Cell, Diffuse" 22522790 Systemic microRNA-34a delivery induces apoptosis and abrogates growth of diffuse large B-cell lymphoma in vivo. other hsa-mir-125b Human Immunodeficiency Virus Infection 22527633 "Researchers have recently demonstrated the presence of anti-HIV-1 microRNAs (miR-28, miR-125b, miR-150, miR-223, and miR-382) in monocytes, macrophages, and CD4+ T cells, which are the primary targets of HIV infection." other hsa-mir-150 Human Immunodeficiency Virus Infection 22527633 "Researchers have recently demonstrated the presence of anti-HIV-1 microRNAs (miR-28, miR-125b, miR-150, miR-223, and miR-382) in monocytes, macrophages, and CD4+ T cells, which are the primary targets of HIV infection." other hsa-mir-223 Human Immunodeficiency Virus Infection 22527633 "Researchers have recently demonstrated the presence of anti-HIV-1 microRNAs (miR-28, miR-125b, miR-150, miR-223, and miR-382) in monocytes, macrophages, and CD4+ T cells, which are the primary targets of HIV infection." other hsa-mir-28 Human Immunodeficiency Virus Infection 22527633 "Researchers have recently demonstrated the presence of anti-HIV-1 microRNAs (miR-28, miR-125b, miR-150, miR-223, and miR-382) in monocytes, macrophages, and CD4+ T cells, which are the primary targets of HIV infection." other hsa-mir-382 Human Immunodeficiency Virus Infection 22527633 "Researchers have recently demonstrated the presence of anti-HIV-1 microRNAs (miR-28, miR-125b, miR-150, miR-223, and miR-382) in monocytes, macrophages, and CD4+ T cells, which are the primary targets of HIV infection." other hsa-mir-21 Glioblastoma 22528454 MicroRNA-21 inhibitor sensitizes human glioblastoma U251 stem cells to chemotherapeutic drug temozolomide. other hsa-mir-21 Heart Failure 22529925 Transfection assay revealed that both Ago1 and Ago2 synergistically induced miR-21 and miR-21* when the mir-21 plasmid was co-transfected with either. other hsa-mir-204 Hypertension 22534459 "This correlates with a down-regulation of miR-204 as well as an up-regulation of miR-21 in PLs, which in turn corresponds to enhanced cell proliferation." other hsa-mir-21 Hypertension 22534459 "This correlates with a down-regulation of miR-204 as well as an up-regulation of miR-21 in PLs, which in turn corresponds to enhanced cell proliferation." other hsa-mir-375 Colorectal Carcinoma 22535378 "In formalin-fixed paraffin-embedded surgical tissue samples, a combination of miR-375, miR-424 and miR-92a yielded an accuracy of 94% (AUC=0.968) in discriminating carcinomas from adenomas. " other hsa-mir-424 Colorectal Carcinoma 22535378 "In formalin-fixed paraffin-embedded surgical tissue samples, a combination of miR-375, miR-424 and miR-92a yielded an accuracy of 94% (AUC=0.968) in discriminating carcinomas from adenomas. " other hsa-mir-92a Colorectal Carcinoma 22535378 "In formalin-fixed paraffin-embedded surgical tissue samples, a combination of miR-375, miR-424 and miR-92a yielded an accuracy of 94% (AUC=0.968) in discriminating carcinomas from adenomas. " other hsa-mir-206 Rhabdomyosarcoma 22541669 miR-206 integrates multiple components of differentiation pathways to control the transition from growth to differentiation in rhabdomyosarcoma cells. other hsa-mir-125b Heart Failure 22545159 "These studies identified miR-125b as an important regulator of hESC differentiation in general, and the development of hESC-derived mesoderm and cardiac muscle in particular." other hsa-mir-142 Systemic Lupus Erythematosus 22549634 Decreased miR-142-3p/5p expression causes CD4(+) T cell activation and B cell hyperstimulation in systemic lupus erythematosus. other hsa-mir-126 "Carcinoma, Hepatocellular" 22552153 recurrence-related in hepatocellular carcinoma other hsa-mir-147a "Carcinoma, Hepatocellular" 22552153 recurrence-related in hepatocellular carcinoma other hsa-mir-19a "Carcinoma, Hepatocellular" 22552153 recurrence-related in hepatocellular carcinoma other hsa-mir-223 "Carcinoma, Hepatocellular" 22552153 recurrence-related in hepatocellular carcinoma other hsa-mir-24-1 "Carcinoma, Hepatocellular" 22552153 recurrence-related in hepatocellular carcinoma other hsa-mir-24-2 "Carcinoma, Hepatocellular" 22552153 recurrence-related in hepatocellular carcinoma other hsa-mir-708 Prostate Neoplasms 22552290 miRNA-708 control of CD44+ prostate cancer initiating cells. other hsa-mir-21 Colorectal Carcinoma 22553926 "EGF/Ras efficiently induces the miR-21 primary transcript, but this does not rapidly and simply translate into higher mature miR-21 levels." other hsa-mir-92a-1 Breast Neoplasms 22563438 Downregulation of miR-92a is associated with aggressive breast cancer features and increased tumour macrophage infiltration. other hsa-mir-92a-2 Breast Neoplasms 22563438 Downregulation of miR-92a is associated with aggressive breast cancer features and increased tumour macrophage infiltration. other hsa-mir-34a Glioma 22568628 MicroRNA-34a Suppresses Cell Proliferation and Induces Apoptosis in U87 Glioma Stem Cells. other hsa-mir-22 Heart Failure 22570371 These data indicate that miR-22 functions as an integrator of Ca(2+) homeostasis and myofibrillar protein content during stress in the heart and shed light on the mechanisms that enhance propensity toward heart failure. other hsa-mir-142 Glioblastoma 22570537 Integrated Analysis Reveals hsa-miR-142 as a Representative of a Lymphocyte-Specific Gene Expression and Methylation Signature. other hsa-mir-145 Thrombocytosis 22571696 Recent evidence suggests that haploinsufficiency of the microRNA genes miR-145 and miR-146a may contribute to the thrombocytosis seen in the 5q- syndrome. other hsa-mir-146a Thrombocytosis 22571696 Recent evidence suggests that haploinsufficiency of the microRNA genes miR-145 and miR-146a may contribute to the thrombocytosis seen in the 5q- syndrome. other hsa-mir-221 Asthma 22572970 Inhibition of miRNA-221 Suppresses the Airway Inflammation in Asthma. other hsa-mir-15a Colon Neoplasms 22574716 Vector-based miR-15a/16-1 plasmid inhibits colon cancer growth in vivo. other hsa-mir-16-1 Colon Neoplasms 22574716 Vector-based miR-15a/16-1 plasmid inhibits colon cancer growth in vivo. other hsa-mir-15a Immune System Disease [unspecific] 22578383 "In conclusion, our data support the involvement of elevated miR-15a in autoimmune disease development in B/W mice and suggest that decreasing this microRNA might be beneficial in B/W mice." other hsa-mir-205 Breast Neoplasms 22578566 Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer. other hsa-mir-146a Asthma 22580216 "These observations suggest that microRNA-181a, -146a and -146b are proinflammatory factors in asthma, and that down-regulation of miRNA-146a may partially account for the anti-inflammatory effect of dexamethasone." other hsa-mir-146b Asthma 22580216 "These observations suggest that microRNA-181a, -146a and -146b are proinflammatory factors in asthma, and that down-regulation of miRNA-146a may partially account for the anti-inflammatory effect of dexamethasone." other hsa-mir-181a Asthma 22580216 "These observations suggest that microRNA-181a, -146a and -146b are proinflammatory factors in asthma, and that down-regulation of miRNA-146a may partially account for the anti-inflammatory effect of dexamethasone." other hsa-mir-21 Cardiac Fibrosis 22580345 "we identify the protective transcriptome signature of enhanced PI3K¦Á signaling in the context of pathological hypertrophy, and demonstrate the regulation of TGF-¦Â/miR-21 by which enhanced PI3K¦Á signaling protects against cardiac fibrosis." other hsa-mir-502 Colon Neoplasms 22580605 Inhibition of autophagy and tumor growth in colon cancer by miR-502. other hsa-mir-9 Immune System Disease [unspecific] 22585398 "Using microarray and deep sequencing approaches, we detected an increase in the abundance of miR-9 in activated human CD4(+) T cells." other hsa-mir-122 Hepatitis C Virus Infection 22593164 Expression of MicroRNA miR-122 Facilitates an Efficient Replication in Nonhepatic Cells upon Infection with Hepatitis C Virus. other hsa-mir-155 "Lymphoma, Large B-Cell, Diffuse" 22609116 miR-155 Regulates the PI3K-AKT pathway in diffuse large B-cell lymphoma. other hsa-mir-106b Myocardial Infarction 22613985 MiR-106b and MiR-15b modulate apoptosis and angiogenesis in myocardial infarction. other hsa-let-7g Obesity 22614057 "Maternal obesity downregulates microRNA let-7g expression, a possible mechanism for enhanced adipogenesis during ovine fetal skeletal muscle development." other hsa-mir-30a "Leukemia, Myeloid, Chronic" 22617440 microRNA 30A promotes autophagy in response to cancer therapy. other hsa-mir-21 Breast Neoplasms 22618231 "Regulatory interplay between miR-21, JAG1 and 17beta-estradiol (E2) in breast cancer cells." other hsa-mir-23a Colorectal Carcinoma 22628407 miR-23a promotes the transition from indolent to invasive colorectal cancer. other hsa-mir-204 Breast Neoplasms 22629385 "Gene expression analysis of miR-204 and miR-379-transfected cells indicated that these miRNAs downregulated the expression of several genes involved in TGF-¦Â signaling, including prostaglandin-endoperoxide synthase 2 (PTGS2)." other hsa-mir-379 Breast Neoplasms 22629385 "Gene expression analysis of miR-204 and miR-379-transfected cells indicated that these miRNAs downregulated the expression of several genes involved in TGF-¦Â signaling, including prostaglandin-endoperoxide synthase 2 (PTGS2)." other hsa-mir-499a "Carcinoma, Hepatocellular" 22641068 Histone Deacetylases Activate Hepatocyte Growth Factor Signaling by Repressing MicroRNA-449 in Hepatocellular Carcinoma Cells. other hsa-mir-499b "Carcinoma, Hepatocellular" 22641068 Histone Deacetylases Activate Hepatocyte Growth Factor Signaling by Repressing MicroRNA-449 in Hepatocellular Carcinoma Cells. other hsa-let-7 Diffuse Lipomatosis 22642449 First description of inhibition of let-7 microRNA expression and HMGA2 overexpression in a case of deep-seated diffuse lipomatosis. other hsa-mir-107 "Diabetes Mellitus, Type 2" 22645244 miR-107: a Toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes. other hsa-mir-107 Obesity 22645244 miR-107: a Toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes. other hsa-mir-20a Endometriosis 22648654 Hypoxia-induced microRNA-20a expression increases ERK phosphorylation and angiogenic gene expression in endometriotic stromal cells. other hsa-mir-34a Cardiovascular Diseases [unspecific] 22651868 Micro-RNA-34a contributes to the impaired function of bone marrow-derived mononuclear cells from patients with cardiovascular disease. other hsa-mir-31 Lung Fibrosis 22661007 miR-31 is a negative regulator of fibrogenesis and pulmonary fibrosis. other hsa-mir-34a Neuroblastoma 22662276 Inhibition of neuroblastoma tumor growth by targeted delivery of microRNA-34a using anti-disialoganglioside GD2 coated nanoparticles. other hsa-mir-9-1 Head And Neck Neoplasms 22664743 IRS-1 suppresses metastasis of head and neck cancer possibly through miR-9 other hsa-mir-9-2 Head And Neck Neoplasms 22664743 IRS-1 suppresses metastasis of head and neck cancer possibly through miR-9 other hsa-mir-9-3 Head And Neck Neoplasms 22664743 IRS-1 suppresses metastasis of head and neck cancer possibly through miR-9 other hsa-mir-193b Melanoma 22665054 "Taken together, our study suggests that downregulation of miR-193b may contribute to increased STMN1 expression in melanoma, which consequently promotes migration and proliferation of tumor cells." other hsa-mir-208a Hypertension 22666483 "this work reveals an original aldosterone-dependent inhibition of miR-208a in hypertension, resulting in the inhibition of ¦Â-myosin heavy chain expression through the induction of its transcriptional repressor Sox6." other hsa-mir-208b Hypertension 22666483 "Besides, the AH-induced increase of ?MyHC and its intronic miRNA-208b was prevented in AS-Ren." other hsa-mir-210 Pancreatic Neoplasms 22672828 "miR-210 expression in PC cells is induced by hypoxia through a HIF-1alpha-dependent pathway, but does not influence PC cell proliferation." other hsa-mir-17 Colon Neoplasms 22677902 "miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer." other hsa-mir-19a Colon Neoplasms 22677902 "miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer." other hsa-mir-21 Colon Neoplasms 22677902 "miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer." other hsa-mir-155 "Leukemia, Myeloid, Acute" 22681934 MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status. other hsa-mir-424 "Leukemia, Myeloid, Acute" 22681934 MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status. other hsa-mir-10b Choriocarcinoma 22682079 The role of miR-10b in metastatic pancreatic ductal adenocarcinoma. other hsa-mir-376a-1 "Carcinoma, Hepatocellular" 22684007 miR-376a suppresses proliferation and induces apoptosis in hepatocellular carcinoma. other hsa-mir-376a-2 "Carcinoma, Hepatocellular" 22684007 miR-376a suppresses proliferation and induces apoptosis in hepatocellular carcinoma. other hsa-mir-23a Colorectal Carcinoma 22684455 "miR-23a, a critical regulator of migRation and metastasis in colorectal cancer." other hsa-mir-21 Esophageal Neoplasms 22689922 Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer. other hsa-mir-31 Esophageal Neoplasms 22689922 Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer. other hsa-mir-124 Glioblastoma 22701651 "Significantly, REST is highly expressed in self-renewing tumorigenic-competent GBM cells and its knock down strongly reduces their self-renewal in vitro and tumor-initiating capacity in vivo and affects levels of miR-124 and its downstream targets." other hsa-mir-31 Esophageal Neoplasms 22706599 MicroRNA-31 modulates tumour sensitivity to radiation in oesophageal adenocarcinoma. other hsa-mir-200c Cholangiocarcinoma 22707408 "Inactivation of miR-200c resulted in an induction of EMT, whereas activation of miR-200c led to a reduction of EMT including a reduced cell migration and invasion in ICC cells." other hsa-mir-125b-1 Glioblastoma 22711523 miR-125b expression plays an essential role in the invasion of glioblastoma CD133-positive cells but not CD133-negative cells. other hsa-mir-125b-2 Glioblastoma 22711523 miR-125b expression plays an essential role in the invasion of glioblastoma CD133-positive cells but not CD133-negative cells. other hsa-mir-29b-1 Preeclampsia 22716646 "MicroRNA-29b contributes to pre-eclampsia through its effects on apoptosis, invasion and angiogenesis of trophoblast cells." other hsa-mir-29b-2 Preeclampsia 22716646 "MicroRNA-29b contributes to pre-eclampsia through its effects on apoptosis, invasion and angiogenesis of trophoblast cells." other hsa-mir-31 Oral Leukoplakia 22719913 Upregulation of miR-31* is negatively associated with recurrent/newly formed oral leukoplakia. other hsa-mir-196b Glioblastoma 22723849 Upregulation of miR-196b confers a poor prognosis in glioblastoma patients via inducing a proliferative phenotype. other hsa-mir-200c Colorectal Carcinoma 22735571 MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis. other hsa-mir-31 Systemic Lupus Erythematosus 22736314 microRNA-31 is a novel regulator contributing to impaired IL-2 production in T cells from patients with systemic lupus erythematosus. other hsa-mir-101 Bladder Neoplasms 22745731 "The combination of four (miR-101, miR-125a-5p, miR-148b, and miR-151-5p) or three (miR-148b, miR-181b, and miR-874,) reference miRNAs is recommended for normalization." other hsa-mir-125a Bladder Neoplasms 22745731 "The combination of four (miR-101, miR-125a-5p, miR-148b, and miR-151-5p) or three (miR-148b, miR-181b, and miR-874,) reference miRNAs is recommended for normalization." other hsa-mir-148b Bladder Neoplasms 22745731 "The combination of four (miR-101, miR-125a-5p, miR-148b, and miR-151-5p) or three (miR-148b, miR-181b, and miR-874,) reference miRNAs is recommended for normalization." other hsa-mir-151 Bladder Neoplasms 22745731 "The combination of four (miR-101, miR-125a-5p, miR-148b, and miR-151-5p) or three (miR-148b, miR-181b, and miR-874,) reference miRNAs is recommended for normalization." other hsa-mir-181b Bladder Neoplasms 22745731 "The combination of four (miR-101, miR-125a-5p, miR-148b, and miR-151-5p) or three (miR-148b, miR-181b, and miR-874,) reference miRNAs is recommended for normalization." other hsa-mir-874 Bladder Neoplasms 22745731 "The combination of four (miR-101, miR-125a-5p, miR-148b, and miR-151-5p) or three (miR-148b, miR-181b, and miR-874,) reference miRNAs is recommended for normalization." other hsa-mir-499 Heart Failure 22752967 "miR-499 is increased in human and murine cardiac hypertrophy and cardiomyopathy, is sufficient to cause murine heart failure, and accelerates maladaptation to pressure overloading. " other hsa-mir-103 Breast Neoplasms 22753153 Identification of fifteen novel germline variants in the BRCA1 3'UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site. other hsa-mir-21 Glioblastoma 22753745 MicroRNA-21 inhibition enhances in vitro chemosensitivity of temozolomide-resistant glioblastoma cells. other hsa-mir-21 Myocardial Infarction 22760500 Activation of Rac1 by angiotensin II leads to a CTGF- and lysyl oxidase-mediated increase of miR-21 expression contributing to structural remodelling of the atrial myocardium. other hsa-mir-21 "Carcinoma, Oral" 22761427 Keratinization-associated miR-7 and miR-21 Regulate Tumor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal Motifs (RECK) in Oral Cancer. other hsa-mir-7-1 "Carcinoma, Oral" 22761427 Keratinization-associated miR-7 and miR-21 Regulate Tumor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal Motifs (RECK) in Oral Cancer. other hsa-mir-7-2 "Carcinoma, Oral" 22761427 Keratinization-associated miR-7 and miR-21 Regulate Tumor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal Motifs (RECK) in Oral Cancer. other hsa-mir-7-3 "Carcinoma, Oral" 22761427 Keratinization-associated miR-7 and miR-21 Regulate Tumor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal Motifs (RECK) in Oral Cancer. other hsa-mir-24-1 Pancreatic Neoplasms 22761894 "We investigated this possibility by analysis of miR-24-1 expression profiles in parathyroid adenomatous tissues from MEN1 gene mutation carriers, in their sporadic non-MEN1 counterparts, and in normal parathyroid tissue." other hsa-mir-10b Glioma 22766763 Co-inhibition of microRNA-10b and microRNA-21 exerts synergistic inhibition on the proliferation and invasion of human glioma cells. other hsa-mir-21 Glioma 22766763 Co-inhibition of microRNA-10b and microRNA-21 exerts synergistic inhibition on the proliferation and invasion of human glioma cells. other hsa-mir-182 Endometrial Neoplasms 22766795 "In distinguishing endometrial endometrial carcinoma from complex atypical hyperplasia, the composite panel of four miRNAs (miR-182, 183, 200a, 200c) produced 95% sensitivity and 91% specificity." other hsa-mir-183 Endometrial Neoplasms 22766795 "In distinguishing endometrial endometrial carcinoma from complex atypical hyperplasia, the composite panel of four miRNAs (miR-182, 183, 200a, 200c) produced 95% sensitivity and 91% specificity." other hsa-mir-200a Endometrial Neoplasms 22766795 "In distinguishing endometrial endometrial carcinoma from complex atypical hyperplasia, the composite panel of four miRNAs (miR-182, 183, 200a, 200c) produced 95% sensitivity and 91% specificity." other hsa-mir-200c Endometrial Neoplasms 22766795 "In distinguishing endometrial endometrial carcinoma from complex atypical hyperplasia, the composite panel of four miRNAs (miR-182, 183, 200a, 200c) produced 95% sensitivity and 91% specificity." other hsa-mir-221 Thyroid Neoplasms 22771635 While a combination of miR-221 and 222 when used in a diagnostic panel could provide fairly good accuracy additional markers may need to be investigated to augment their diagnostic utility. other hsa-mir-222 Thyroid Neoplasms 22771635 While a combination of miR-221 and 222 when used in a diagnostic panel could provide fairly good accuracy additional markers may need to be investigated to augment their diagnostic utility. other hsa-mir-93 "Carcinoma, Hepatocellular" 22773266 Downregulation of MiR-93 Expression Reduces Cell Proliferation and Clonogenicity of HepG2 Cells. other hsa-mir-15a Multiple Myeloma 22781767 BMSCs suppress the proliferation of myeloma cells and regulate the drug sensitivity of myeloma cells through the inhibited expression of miRNA-15a/-16. IL-6 plays a pivotal role in the occurrence of drug resistance. other hsa-mir-16 Multiple Myeloma 22781767 BMSCs suppress the proliferation of myeloma cells and regulate the drug sensitivity of myeloma cells through the inhibited expression of miRNA-15a/-16. IL-6 plays a pivotal role in the occurrence of drug resistance. other hsa-mir-494 Cholangiocarcinoma 22785131 Coordinated effects of microRNA-494 induce G/M arrest in human cholangiocarcinoma. other hsa-mir-21 Ischemia-Reperfusion Injury 22785173 "Thus, upregulation of miR-21 contributes to the protective effect of delayed ischemic preconditioning against subsequent renal ischemia-reperfusion injury." other hsa-mir-21 Bladder Neoplasms 22788411 "The effect of normalization was tested with miR-21 as the target gene, as this was previously suggested to be upregulated in cancer patients' serum." other hsa-mir-155 Lung Neoplasms 22796123 "The present study demonstrated that intracellular miR-155 could be successfully and quickly detected by novel miR-155 MBs. As a noninvasive monitoring approach, MBs could be used to diagnose lung cancer at early stage through molecular imaging." other hsa-mir-335 Gastric Neoplasms 22802949 A high frequency recurrence and poor survival were observed in GC cases with high level of hsa-miR-335 (P<0.001). other hsa-mir-200b Colorectal Carcinoma 22804917 In KRAS mutated tumours increased miR-200b and decreased miR-143 expression were associated with a good progression-free survival . other hsa-mir-34a "Leukemia, Myeloid, Acute" 22810507 "Clinically, low miR-34a expression and TP53 alterations predicted for chemotherapy resistance and inferior outcome. Notably, in TP53(unaltered) CK-AML, high miR-34a expression predicted for inferior overall survival (OS), whereas in TP53(biallelic altered) CK-AML, high miR-34a expression pointed to better OS." other hsa-mir-101-1 Endomyocardial Fibrosis 22811578 MicroRNA-101 Inhibited Postinfarct Cardiac Fibrosis and Improved Left Ventricular Compliance via the FBJ Osteosarcoma Oncogene/Transforming Growth Factor Pathway. other hsa-mir-101-2 Endomyocardial Fibrosis 22811578 MicroRNA-101 Inhibited Postinfarct Cardiac Fibrosis and Improved Left Ventricular Compliance via the FBJ Osteosarcoma Oncogene/Transforming Growth Factor-§Ø©ã Pathway. other hsa-let-7i Ovarian Neoplasms 22812695 Our study indicated that this MUC1/let-7i chimera can specifically reverse chemoresistance to paclitaxel. other hsa-mir-205 Prostate Neoplasms 22815235 "Additionally, for two genes that are deregulated in PCa (heterogeneous nuclear ribonucleoprotein K, hnRNP-K, and vascular endothelial growth factor A, VEGF-A), we identified two regulatory miRNAs, miR-205 and miR-29b." other hsa-mir-29b Prostate Neoplasms 22815235 "Additionally, for two genes that are deregulated in PCa (heterogeneous nuclear ribonucleoprotein K, hnRNP-K, and vascular endothelial growth factor A, VEGF-A), we identified two regulatory miRNAs, miR-205 and miR-29b." other hsa-mir-122 "Carcinoma, Hepatocellular" 22820284 "Knockout mice also displayed hepatic inflammation, fibrosis, and a high incidence of hepatocellular carcinoma, suggesting that miR-122 has a tumor suppressor role in hepatocytes." other hsa-mir-125b "Carcinoma, Hepatocellular" 22824797 "downregulation of miR-125b was a frequent event in hepatocellular carcinoma (HCC) tissues, and the miR-125b level was positively associated with the rate of apoptosis in HCC tissues." other hsa-mir-9-1 Melanoma 22825752 MicroRNA-9 suppresses uveal melanoma cell migration and invasion through the NF-kB1 pathway. other hsa-mir-9-2 Melanoma 22825752 MicroRNA-9 suppresses uveal melanoma cell migration and invasion through the NF-kB1 pathway. other hsa-mir-9-3 Melanoma 22825752 MicroRNA-9 suppresses uveal melanoma cell migration and invasion through the NF-kB1 pathway. other hsa-mir-124 Glioblastoma 22829753 "Our follow up topological and functional analyses of the subnetwork revealed that six miRNAs (miR-124, miR-137, miR-219-5p, miR-34a, miR-9, and miR-92b) might play important roles in GBM, including some results that are supported by previous studies." other hsa-mir-137 Glioblastoma 22829753 "Our follow up topological and functional analyses of the subnetwork revealed that six miRNAs (miR-124, miR-137, miR-219-5p, miR-34a, miR-9, and miR-92b) might play important roles in GBM, including some results that are supported by previous studies." other hsa-mir-219 Glioblastoma 22829753 "Our follow up topological and functional analyses of the subnetwork revealed that six miRNAs (miR-124, miR-137, miR-219-5p, miR-34a, miR-9, and miR-92b) might play important roles in GBM, including some results that are supported by previous studies." other hsa-mir-34a Glioblastoma 22829753 "Our follow up topological and functional analyses of the subnetwork revealed that six miRNAs (miR-124, miR-137, miR-219-5p, miR-34a, miR-9, and miR-92b) might play important roles in GBM, including some results that are supported by previous studies." other hsa-mir-9 Glioblastoma 22829753 "Our follow up topological and functional analyses of the subnetwork revealed that six miRNAs (miR-124, miR-137, miR-219-5p, miR-34a, miR-9, and miR-92b) might play important roles in GBM, including some results that are supported by previous studies." other hsa-mir-92b Glioblastoma 22829753 "Our follow up topological and functional analyses of the subnetwork revealed that six miRNAs (miR-124, miR-137, miR-219-5p, miR-34a, miR-9, and miR-92b) might play important roles in GBM, including some results that are supported by previous studies." other hsa-mir-210 Ischemic Diseases [unspecific] 22833359 miR-210 activates notch signaling pathway in angiogenesis induced by cerebral ischemia. other hsa-mir-155 Glioblastoma 22834637 A relationship between knock-down of miR-155 and re-expression of GABRA 1 protein in vivo was recently individuated. other hsa-mir-185 Glioma 22834685 LRRC4 inhibits glioma cell growth and invasion through a miR-185-dependent pathway. other hsa-mir-210 Preeclampsia 22840297 MIR-210 modulates mitochondrial respiration in placenta with preeclampsia. other hsa-mir-144 "Leukemia, Myeloid, Chronic" 22842456 Myc induced miR-144/451 contributes to the acquired imatinib resistance in chronic myelogenous leukemia cell K562. other hsa-mir-451a "Leukemia, Myeloid, Chronic" 22842456 Myc induced miR-144/451 contributes to the acquired imatinib resistance in chronic myelogenous leukemia cell K562. other hsa-mir-451b "Leukemia, Myeloid, Chronic" 22842456 Myc induced miR-144/451 contributes to the acquired imatinib resistance in chronic myelogenous leukemia cell K562. other hsa-mir-21 Heart Failure 22842854 "TMZ improved RV function (as indicated by an increase in tricuspid annular plane systolic excursion), and inhibited fibrosis. TMZ also protects RVMCs againts apoptosis and increases miR-21 expression." other hsa-mir-148b "Lymphoma, Non-Hodgkin" 22843616 MicroRNA-148b enhances the radiosensitivity of non-Hodgkin's Lymphoma cells by promoting radiation-induced apoptosis. other hsa-mir-126 Colorectal Carcinoma 22848274 Elevated microRNA-126 is associated with high vascular endothelial growth factor receptor 2 expression levels and high microvessel density in colorectal cancer. other hsa-mir-433 Myeloproliferative Neoplasms 22864358 miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation. other hsa-mir-17 Retinoblastoma 22864477 "Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation." other hsa-mir-18a Retinoblastoma 22864477 "Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation." other hsa-mir-19b-1 Retinoblastoma 22864477 "Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation." other hsa-mir-20a Retinoblastoma 22864477 "Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation." other hsa-mir-92a-1 Retinoblastoma 22864477 "Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation." other hsa-mir-21 Lung Neoplasms 22866162 The detection of miR-21 expression yielded 78.80% sensitivity and 100.00% specificity in the diagnosis of lung cancer. other hsa-mir-200a "Carcinoma, Hepatocellular" 22868917 MicroRNA-200a and -200b Mediated Hepatocellular Carcinoma Cell Migration Through the Epithelial to Mesenchymal Transition Markers. other hsa-mir-200b "Carcinoma, Hepatocellular" 22868917 MicroRNA-200a and -200b Mediated Hepatocellular Carcinoma Cell Migration Through the Epithelial to Mesenchymal Transition Markers. other hsa-mir-21 Hypertrophy 22879939 TGFbeta-Stimulated MicroRNA-21 Utilizes PTEN to Orchestrate AKT/mTORC1 Signaling for Mesangial Cell Hypertrophy and Matrix Expansion. other hsa-mir-124-1 Colorectal Carcinoma 22885837 Downregulation of microRNA-124 is an independent prognostic factor in patients with colorectal cancer. other hsa-mir-124-2 Colorectal Carcinoma 22885837 Downregulation of microRNA-124 is an independent prognostic factor in patients with colorectal cancer. other hsa-mir-205 Melanoma 22890556 miR-205 is a tumor suppressor microRNAin malignant melanoma. other hsa-mir-204 Neuroblastoma 22892391 MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome. other hsa-mir-27b Metabolic Syndrome 22893262 "we thus speculate that Rb1 may act though PPAR¦Ã to downregulate mir-27b gene transcription and mature miR-27b activity, which in turn promotes PPAR¦Ã expression and adipogenesis." other hsa-mir-141 Ovarian Neoplasms 22897840 "Some genes involved in EMT, such as BMP and activin membrane-bound inhibitor (BAMBI), and mir-141 resulted in association with overall or progression free survival." other hsa-mir-126 "Carcinoma, Lung, Non-Small-Cell" 22900072 MicroRNA-126 Inhibits Tumor Cell Growth and Its Expression Level Correlates with Poor Survival in Non-Small Cell Lung Cancer Patients. other hsa-mir-320a Diabetes Mellitus 22900199 miR-320 Regulates Glucose-Induced Gene Expression in Diabetes. other hsa-mir-20a Breast Neoplasms 22901144 Differential Distribution of miR-20a and miR-20b may Underly Metastatic Heterogeneity of Breast Cancers. other hsa-mir-153-1 Rectal Neoplasms 22903298 "These signatures consisted of three miRNA transcripts (miR-16, miR-590-5p and miR-153) to predict complete vs. incomplete response and two miRNA transcript (miR-519c-3p and miR-561) to predict good vs. poor response with a median accuracy of 100 %." other hsa-mir-153-2 Rectal Neoplasms 22903298 "These signatures consisted of three miRNA transcripts (miR-16, miR-590-5p and miR-153) to predict complete vs. incomplete response and two miRNA transcript (miR-519c-3p and miR-561) to predict good vs. poor response with a median accuracy of 100 %." other hsa-mir-16-1 Rectal Neoplasms 22903298 "These signatures consisted of three miRNA transcripts (miR-16, miR-590-5p and miR-153) to predict complete vs. incomplete response and two miRNA transcript (miR-519c-3p and miR-561) to predict good vs. poor response with a median accuracy of 100 %." other hsa-mir-16-2 Rectal Neoplasms 22903298 "These signatures consisted of three miRNA transcripts (miR-16, miR-590-5p and miR-153) to predict complete vs. incomplete response and two miRNA transcript (miR-519c-3p and miR-561) to predict good vs. poor response with a median accuracy of 100 %." other hsa-mir-519c Rectal Neoplasms 22903298 "These signatures consisted of three miRNA transcripts (miR-16, miR-590-5p and miR-153) to predict complete vs. incomplete response and two miRNA transcript (miR-519c-3p and miR-561) to predict good vs. poor response with a median accuracy of 100 %." other hsa-mir-561 Rectal Neoplasms 22903298 "These signatures consisted of three miRNA transcripts (miR-16, miR-590-5p and miR-153) to predict complete vs. incomplete response and two miRNA transcript (miR-519c-3p and miR-561) to predict good vs. poor response with a median accuracy of 100 %." other hsa-mir-590 Rectal Neoplasms 22903298 "These signatures consisted of three miRNA transcripts (miR-16, miR-590-5p and miR-153) to predict complete vs. incomplete response and two miRNA transcript (miR-519c-3p and miR-561) to predict good vs. poor response with a median accuracy of 100 %." other hsa-mir-181 Endometrial Neoplasms 22911744 "Three miRNAs families, miR-181, miR-183 and miR-200, are down-regulated during the decidualization process." other hsa-mir-183 Endometrial Neoplasms 22911744 "Three miRNAs families, miR-181, miR-183 and miR-200, are down-regulated during the decidualization process." other hsa-mir-200 Endometrial Neoplasms 22911744 "Three miRNAs families, miR-181, miR-183 and miR-200, are down-regulated during the decidualization process." other hsa-mir-338 Hepatitis B Virus Infection 22912826 The Effect of miR-338-3p on HBx Deletion-Mutant (HBx-d382) Mediated Liver-Cell Proliferation through CyclinD1 Regulation. other hsa-mir-124-1 Glioma 22918790 CDA-2 induces cell differentiation through suppressing Twist/SLUG signaling via miR-124 in glioma. other hsa-mir-124-2 Glioma 22918790 CDA-2 induces cell differentiation through suppressing Twist/SLUG signaling via miR-124 in glioma. other hsa-mir-15b Cervical Neoplasms 22920753 "These data suggested that down-regulation of NDRG2 could enhance sensitivity of Hela cells to cisplatin through inhibiting Bcl-2 protein expression, which might be mediated by up-regulating miR-15b and miR-16." other hsa-mir-16 Cervical Neoplasms 22920753 "These data suggested that down-regulation of NDRG2 could enhance sensitivity of Hela cells to cisplatin through inhibiting Bcl-2 protein expression, which might be mediated by up-regulating miR-15b and miR-16." other hsa-mir-138-1 Glioma 22921398 miR-138 has a critical role in promoting growth and survival of bona fide tumor-initiating cells with self-renewal potential. other hsa-mir-138-2 Glioma 22921398 miR-138 has a critical role in promoting growth and survival of bona fide tumor-initiating cells with self-renewal potential. other hsa-mir-141 Melanoma 22927992 "The strongest inhibitors of melanoma cell proliferation, including the miR-15/16, miR-141/200a and miR-96/182 families of miRNAs and miR-203." other hsa-mir-15a Melanoma 22927992 "The strongest inhibitors of melanoma cell proliferation, including the miR-15/16, miR-141/200a and miR-96/182 families of miRNAs and miR-203." other hsa-mir-15b Melanoma 22927992 "The strongest inhibitors of melanoma cell proliferation, including the miR-15/16, miR-141/200a and miR-96/182 families of miRNAs and miR-203." other hsa-mir-16-1 Melanoma 22927992 "The strongest inhibitors of melanoma cell proliferation, including the miR-15/16, miR-141/200a and miR-96/182 families of miRNAs and miR-203." other hsa-mir-16-2 Melanoma 22927992 "The strongest inhibitors of melanoma cell proliferation, including the miR-15/16, miR-141/200a and miR-96/182 families of miRNAs and miR-203." other hsa-mir-182 Melanoma 22927992 "The strongest inhibitors of melanoma cell proliferation, including the miR-15/16, miR-141/200a and miR-96/182 families of miRNAs and miR-203." other hsa-mir-200a Melanoma 22927992 "The strongest inhibitors of melanoma cell proliferation, including the miR-15/16, miR-141/200a and miR-96/182 families of miRNAs and miR-203." other hsa-mir-203 Melanoma 22927992 "The strongest inhibitors of melanoma cell proliferation, including the miR-15/16, miR-141/200a and miR-96/182 families of miRNAs and miR-203." other hsa-mir-96 Melanoma 22927992 "The strongest inhibitors of melanoma cell proliferation, including the miR-15/16, miR-141/200a and miR-96/182 families of miRNAs and miR-203." other hsa-mir-151a Prostate Neoplasms 22928040 Genistein Suppresses Prostate Cancer Growth through Inhibition of Oncogenic MicroRNA-151. other hsa-mir-151b Prostate Neoplasms 22928040 Genistein Suppresses Prostate Cancer Growth through Inhibition of Oncogenic MicroRNA-151. other hsa-mir-143 Prostate Neoplasms 22929553 "Several miRNAs such as miR-96, miR-182, and miR-143 demonstrated high influence on their target protein complexes and could explain most of the gene expression changes in our analyzed prostate cancer data set." other hsa-mir-182 Prostate Neoplasms 22929553 "Several miRNAs such as miR-96, miR-182, and miR-143 demonstrated high influence on their target protein complexes and could explain most of the gene expression changes in our analyzed prostate cancer data set." other hsa-mir-96 Prostate Neoplasms 22929553 "Several miRNAs such as miR-96, miR-182, and miR-143 demonstrated high influence on their target protein complexes and could explain most of the gene expression changes in our analyzed prostate cancer data set." other hsa-mir-143 Myelodysplastic Syndromes 22929976 Lenalidomide selectively abrogated progenitor activity in cells depleted of miR-143 and miR-145 supporting a key role for miR-143/145 in the sensitivity to lenalidomide of del(5q) myelodysplastic syndrome patients. other hsa-mir-145 Myelodysplastic Syndromes 22929976 Lenalidomide selectively abrogated progenitor activity in cells depleted of miR-143 and miR-145 supporting a key role for miR-143/145 in the sensitivity to lenalidomide of del(5q) myelodysplastic syndrome patients. other hsa-let-7b "Carcinoma, Hepatocellular" 22934260 TLR4 signaling induces the release of microparticles by tumor cells that regulate inflammatory cytokine IL-6 of macrophages via microRNA let-7b. other hsa-mir-296 Esophageal Neoplasms 22939244 differentially regulated other hsa-mir-127 "Lymphoma, Burkitt" 22941339 Epstein-Barr nuclear antigen 1 induces expression of the cellular microRNA hsa-miR-127 and impairing B-cell differentiation in EBV-infected memory B cells. other hsa-mir-125b-1 "Carcinoma, Hepatocellular" 22942733 MicroRNA-125b Functions as a Tumor Suppressor in Hepatocellular Carcinoma Cells. other hsa-mir-125b-2 "Carcinoma, Hepatocellular" 22942733 MicroRNA-125b Functions as a Tumor Suppressor in Hepatocellular Carcinoma Cells. other hsa-mir-101-1 Pancreatic Neoplasms 22943841 Restoration of E-cadherin expression in pancreatic ductal adenocarcinoma treated with microRNA-101. other hsa-mir-101-2 Pancreatic Neoplasms 22943841 Restoration of E-cadherin expression in pancreatic ductal adenocarcinoma treated with microRNA-101. other hsa-mir-125b-1 Myelodysplastic Syndromes 22944560 Myelodysplastic syndrome with a t(2;11)(p21;q23-24) and translocation breakpoint close to miR-125b-1. other hsa-mir-143 Prostate Neoplasms 22948942 miR-143 and miR-145 inhibit stem cell characteristics of PC-3 prostate cancer cells. other hsa-mir-145 Prostate Neoplasms 22948942 miR-143 and miR-145 inhibit stem cell characteristics of PC-3 prostate cancer cells. other hsa-mir-146a Breast Neoplasms 22949171 MicroRNA-146a suppresses metastatic activity in brain metastasis. other hsa-mir-15a Infection [unspecific] 22953717 "Moreover, miR-664-5p, miR-451 and miR-15a appear as very promising candidates for microRNAs involved in response to pathogen infection." other hsa-mir-451 Infection [unspecific] 22953717 "Moreover, miR-664-5p, miR-451 and miR-15a appear as very promising candidates for microRNAs involved in response to pathogen infection." other hsa-mir-664 Infection [unspecific] 22953717 "Moreover, miR-664-5p, miR-451 and miR-15a appear as very promising candidates for microRNAs involved in response to pathogen infection." other hsa-mir-138-1 Urinary Bladder Cancer 22954303 Decreasing miR-138 increased the cisplatin sensitivity in half of the cell lines and increasing miR-27a and miR-642 generally increased cisplatin sensitivity. other hsa-mir-138-2 Urinary Bladder Cancer 22954303 Decreasing miR-138 increased the cisplatin sensitivity in half of the cell lines and increasing miR-27a and miR-642 generally increased cisplatin sensitivity. other hsa-mir-27a Urinary Bladder Cancer 22954303 Decreasing miR-138 increased the cisplatin sensitivity in half of the cell lines and increasing miR-27a and miR-642 generally increased cisplatin sensitivity. other hsa-mir-642a Urinary Bladder Cancer 22954303 Decreasing miR-138 increased the cisplatin sensitivity in half of the cell lines and increasing miR-27a and miR-642 generally increased cisplatin sensitivity. other hsa-mir-642b Urinary Bladder Cancer 22954303 Decreasing miR-138 increased the cisplatin sensitivity in half of the cell lines and increasing miR-27a and miR-642 generally increased cisplatin sensitivity. other hsa-mir-944 Urinary Bladder Cancer 22954303 "Three miRNAs were associated with both response (to chemotherapy) and survival (886-3p, 923, 944)." other hsa-mir-23b Atherosclerosis 22955103 "In addition, members of the miR-23-27-24 cluster are increased and specifically miR-23b blocks cell cycle progression, whereas miR-27b was shown to reduce endothelial cell repulsive signals." other hsa-mir-27b Atherosclerosis 22955103 "In addition, members of the miR-23-27-24 cluster are increased and specifically miR-23b blocks cell cycle progression, whereas miR-27b was shown to reduce endothelial cell repulsive signals." other hsa-mir-219-2 Inflammation 22957142 "Delayed resolution undermines endogenous resolution programs, altering miR-219-2 expression, increasing pro-inflammatory mediators and compromising SPM production that contribute to failed catabasis and homeostasis." other hsa-mir-210 Melanoma 22962263 "Our findings show how miR-210 induction links hypoxia to immune escape from CTL-mediated lysis, by providing a mechanistic understanding of how this miRNA mediates immunosuppression in oxygen-deprived regions of tumors where cancer stem-like cells and metastatic cellular behaviors are known to evolve." other hsa-let-7c "Leukemia, Myeloid, Acute" 22964640 miRNA let-7c promotes granulocytic differentiation in acute myeloid leukemia. other hsa-mir-122 Hepatitis C Virus Infection 22965312 "these findings indicate that miR-122 and functional lipid metabolism are involved in the tissue tropism of HCV infection. In this review, we would like to focus on the role of miR-122 and lipid metabolism in the cell tropism of HCV." other hsa-mir-122 Metabolic Syndrome 22965541 "These results suggest that proanthocyanidin treatment increased hepatic cholesterol efflux to produce new HDL particles by repressing miR-33, and it reduced lipogenesis by repressing miR-122." other hsa-mir-33 Metabolic Syndrome 22965541 "These results suggest that proanthocyanidin treatment increased hepatic cholesterol efflux to produce new HDL particles by repressing miR-33, and it reduced lipogenesis by repressing miR-122." other hsa-mir-10a Gastric Neoplasms 22969895 miRNA expression profile in primary gastric cancers and paired lymph node metastases indicates that miR-10a plays a role in metastasis from primary gastric cancer to lymph nodes. other hsa-mir-106a Gastrointestinal Neoplasms 22994734 "Under these experimental conditions, MTg-AMOs demonstrated better suppression of the expression of miR-221, miR-106a, miR-21 in gastric cancer cells than that of single AMOs" other hsa-mir-21 Gastrointestinal Neoplasms 22994734 "Under these experimental conditions, MTg-AMOs demonstrated better suppression of the expression of miR-221, miR-106a, miR-21 in gastric cancer cells than that of single AMOs" other hsa-mir-221 Gastrointestinal Neoplasms 22994734 "Under these experimental conditions, MTg-AMOs demonstrated better suppression of the expression of miR-221, miR-106a, miR-21 in gastric cancer cells than that of single AMOs" other hsa-mir-29c Gastric Neoplasms 23001726 The tumor suppressor microRNA-29c is downregulated and restored by celecoxib in human gastric cancer cells. other hsa-mir-182 Glioma 23006329 "we found that TGF-¦Â induced miR-182 expression, leading to prolonged NF-¦ÊB activation." other hsa-mir-1 Neuroblastoma 23022474 "FOXP1 is upregulated as a result of gene fusion or amplification in DLBCL and MALT lymphoma and also repression of miRNAs, such as miR-1, miR-34a and miR-504." other hsa-mir-34a Neuroblastoma 23022474 "FOXP1 is upregulated as a result of gene fusion or amplification in DLBCL and MALT lymphoma and also repression of miRNAs, such as miR-1, miR-34a and miR-504." other hsa-mir-504 Neuroblastoma 23022474 "FOXP1 is upregulated as a result of gene fusion or amplification in DLBCL and MALT lymphoma and also repression of miRNAs, such as miR-1, miR-34a and miR-504." other hsa-mir-29a "Carcinoma, Hepatocellular" 23023935 Our findings demonstrate that the expression of miR-29a is important in the regulation of the SPARC-AKT pathway and HCC growth. other hsa-mir-146 Lung Neoplasms 23035181 "Other significantly differentiated miR families included carcinogenesis-related miR-146, miR-26, and miR-17 (P (FCS) < 0.05)." other hsa-mir-17 Lung Neoplasms 23035181 "Other significantly differentiated miR families included carcinogenesis-related miR-146, miR-26, and miR-17 (P (FCS) < 0.05)." other hsa-mir-26 Lung Neoplasms 23035181 "Other significantly differentiated miR families included carcinogenesis-related miR-146, miR-26, and miR-17 (P (FCS) < 0.05)." other hsa-mir-34a Lung Neoplasms 23036084 microRNA-34a Sensitizes Lung Cancer Cell Lines to DDP Treatment Independent of p53 Status. other hsa-mir-155 Colon Neoplasms 23036199 Adrenaline promotes cell proliferation and increases chemoresistance in colon cancer HT29 cells through induction of miR-155 other hsa-mir-17 "Adenocarcinoma, Lung" 23036707 "Moreover, the expression pattern of miR-17, miR-21, and miR-200a in rBM 3-D culture correlated with the expression of their targets and acinar morphogenesis, a differentiation behavior of lung epithelial cells in rBM 3-D culture" other hsa-mir-200a "Adenocarcinoma, Lung" 23036707 "Moreover, the expression pattern of miR-17, miR-21, and miR-200a in rBM 3-D culture correlated with the expression of their targets and acinar morphogenesis, a differentiation behavior of lung epithelial cells in rBM 3-D culture" other hsa-mir-21 "Adenocarcinoma, Lung" 23036707 "Moreover, the expression pattern of miR-17, miR-21, and miR-200a in rBM 3-D culture correlated with the expression of their targets and acinar morphogenesis, a differentiation behavior of lung epithelial cells in rBM 3-D culture" other hsa-mir-200c Prostate Neoplasms 23041061 Epithelial-to-mesenchymal transition leads to docetaxel resistance in prostate cancer and is mediated by reduced expression of miR-200c and miR-205 other hsa-mir-205 Prostate Neoplasms 23041061 Epithelial-to-mesenchymal transition leads to docetaxel resistance in prostate cancer and is mediated by reduced expression of miR-200c and miR-205 other hsa-mir-205 "Adenocarcinoma, Lung" 23043084 "Two microRNA panels yielded high diagnostic accuracy in discriminating SCLC from NSCLC (miR-29a and miR-375; area under the curve [AUC], 0.991 and 0.982 for training and validation data set, respectively) and in differentiating SQ from AC (miR-205 and miR-34a; AUC, 0.977 and 0.982 for training and validation data set, respectively) in FFPE surgical lung specimens." other hsa-mir-29a "Carcinoma, Lung, Small-Cell" 23043084 "Two microRNA panels yielded high diagnostic accuracy in discriminating SCLC from NSCLC (miR-29a and miR-375; area under the curve [AUC], 0.991 and 0.982 for training and validation data set, respectively) and in differentiating SQ from AC (miR-205 and miR-34a; AUC, 0.977 and 0.982 for training and validation data set, respectively) in FFPE surgical lung specimens." other hsa-mir-34a "Adenocarcinoma, Lung" 23043084 "Two microRNA panels yielded high diagnostic accuracy in discriminating SCLC from NSCLC (miR-29a and miR-375; area under the curve [AUC], 0.991 and 0.982 for training and validation data set, respectively) and in differentiating SQ from AC (miR-205 and miR-34a; AUC, 0.977 and 0.982 for training and validation data set, respectively) in FFPE surgical lung specimens." other hsa-mir-375 "Carcinoma, Lung, Small-Cell" 23043084 "Two microRNA panels yielded high diagnostic accuracy in discriminating SCLC from NSCLC (miR-29a and miR-375; area under the curve [AUC], 0.991 and 0.982 for training and validation data set, respectively) and in differentiating SQ from AC (miR-205 and miR-34a; AUC, 0.977 and 0.982 for training and validation data set, respectively) in FFPE surgical lung specimens." other hsa-mir-34a Heart Diseases [unspecific] 23047694 Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function. other hsa-mir-155 Waldenstrom Macroglobulinemia 23048077 "Importantly, everolimus targeted Waldenstrom macroglobulinemia cells even in the context of bone marrow milieu, where it affected migration, adhesion, and angiogenesis.Everolimus-dependent anti-Waldenstrom macroglobulinemia activity was partially driven by miRNA-155." other hsa-mir-196b Glioma 23049982 "We have provided the first evidence that expression of miR-196b was associated with the occurrence of pre-operative seizures in low-grade gliomas,and may predict seizure prognosis in patients without pre-operative seizures" other hsa-mir-155 "Carcinoma, Renal Cell" 23050614 MicroRNA-155 is a predictive marker for survival in patients with clear cell renal cell carcinoma other hsa-mir-21 Breast Neoplasms 23052036 Endocrine Disruptors Fludioxonil and Fenhexamid Stimulate miR-21 Expression in Breast Cancer Cells other hsa-mir-451a Esophageal Neoplasms 23053883 Effect of miR-451 on the Biological Behavior of the Esophageal Carcinoma Cell Line EC9706 other hsa-mir-498 Neoplasms [unspecific] 23055531 "1,25-Dihydroxyvitamin D3 suppresses telomerase expression and human cancer growth through microRNA-498" other hsa-mir-122 Hepatitis B Virus Infection 23055569 Inhibition of Alpha Interferon (IFN-alpha)-Induced MicroRNA-122 Negatively Affects the Anti-Hepatitis B Virus Efficiency of IFN-§Ø©ã other hsa-mir-148a Colorectal Carcinoma 23056401 The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer other hsa-mir-205 Urinary Bladder Cancer 23056551 miR-205 expression promotes cell proliferation and migration of human cervical cancer cells other hsa-mir-187 Breast Neoplasms 23060431 miR-187 Is an Independent Prognostic Factor in Breast Cancer and Confers Increased Invasive Potential In Vitro other hsa-mir-218-1 Neoplasms [unspecific] 23060446 miR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells other hsa-mir-218-2 Neoplasms [unspecific] 23060446 miR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells other hsa-mir-371a Thyroid Neoplasms 23062364 Activation of the two microRNA clusters C19MC and miR-371-3 does not play prominent role in thyroid cancer other hsa-mir-133a "Cardiomyopathy, Hypertrophic" 23070543 "Consistent with these structural changes, the expression of molecular markers of cardiac hypertrophy were also increased [Nppb(BNP), Myh7-Myh6(¦ÂMHC-¦ÁMHC) (both P < 0.05) and mir-133a (P < 0.01)]." other hsa-mir-143 Pancreatic Neoplasms 23070684 miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway other hsa-mir-146b Colitis 23071818 our data indicates that miRNA-146b and PPAR¦Ã activation may be implicated in the regulation of Th17 responses and colitis in C. difficile-infected mice. other hsa-mir-200c Ovarian Neoplasms 23074172 Restoration of miR-200c to Ovarian Cancer Reduces Tumor Burden and Increases Sensitivity to Paclitaxel other hsa-mir-376a-1 Glioblastoma 23093778 Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells other hsa-mir-376a-2 Glioblastoma 23093778 Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells other hsa-mir-150 Human Immunodeficiency Virus Infection 23094138 "Here, we observed that the expression levels of the cellular factors Trim5¦Á, CypA, APOBEC3G, SAMHD-1, Trim22, tetherin and TREX-1, and the anti-HIV miRNAs miR-28, miR-150, miR-223 and miR-382 was upregulated by IFN-¦Á and IFN-¦Â in macrophages, which may account for the inhibiting effect on viral replication and the antiviral state of these cells." other hsa-mir-223 Human Immunodeficiency Virus Infection 23094138 "Here, we observed that the expression levels of the cellular factors Trim5¦Á, CypA, APOBEC3G, SAMHD-1, Trim22, tetherin and TREX-1, and the anti-HIV miRNAs miR-28, miR-150, miR-223 and miR-382 was upregulated by IFN-¦Á and IFN-¦Â in macrophages, which may account for the inhibiting effect on viral replication and the antiviral state of these cells." other hsa-mir-28 Human Immunodeficiency Virus Infection 23094138 "Here, we observed that the expression levels of the cellular factors Trim5¦Á, CypA, APOBEC3G, SAMHD-1, Trim22, tetherin and TREX-1, and the anti-HIV miRNAs miR-28, miR-150, miR-223 and miR-382 was upregulated by IFN-¦Á and IFN-¦Â in macrophages, which may account for the inhibiting effect on viral replication and the antiviral state of these cells." other hsa-mir-382 Human Immunodeficiency Virus Infection 23094138 "Here, we observed that the expression levels of the cellular factors Trim5¦Á, CypA, APOBEC3G, SAMHD-1, Trim22, tetherin and TREX-1, and the anti-HIV miRNAs miR-28, miR-150, miR-223 and miR-382 was upregulated by IFN-¦Á and IFN-¦Â in macrophages, which may account for the inhibiting effect on viral replication and the antiviral state of these cells." other hsa-mir-18a Nasopharyngeal Neoplasms 23097559 miR-18a promotes malignant progression by impairing microRNA biogenesis in nasopharyngeal carcinoma other hsa-mir-222 Glioblastoma 23099529 Electrochemical detection of miRNA-222 by use of a magnetic bead-based bioassay. other hsa-mir-21 Glioma 23104517 MiR-21 expression in the tumor cell compartment holds unfavorable prognostic value in gliomas other hsa-mir-20a Leukemia 23114118 "It is concluded that the miR-20a sponge is constructed successfully, and Jurkat-S stable cell line is established, in which the expression of miR-20a is inhibited stably." other hsa-mir-17 Pulmonary Hypertension 23114789 "MEX suppressed the hypoxic activation of signal transducer and activator of transcription 3 (STAT3) and the upregulation of the miR-17 superfamily of microRNA clusters, whereas it increased lung levels of miR-204, a key microRNA, the expression of which is decreased in human pulmonary hypertension." other hsa-mir-7-1 Head And Neck Neoplasms 23115635 Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7 other hsa-mir-7-2 Head And Neck Neoplasms 23115635 Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7 other hsa-mir-7-3 Head And Neck Neoplasms 23115635 Regulation of epidermal growth factor receptor signaling and erlotinib sensitivity in head and neck cancer cells by miR-7 other hsa-mir-122 Hepatitis C Virus Infection 23126531 Alcohol Facilitates HCV RNA Replication Via Up-Regulation of miR-122 Expression and Inhibition of Cyclin G1 in Human Hepatoma Cells other hsa-mir-143 Colorectal Carcinoma 23128394 Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression other hsa-mir-145 Colorectal Carcinoma 23128394 Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression other hsa-mir-125b-1 Gastric Neoplasms 23128435 MicroRNA-125b expression in gastric adenocarcinoma and its effect on the proliferation of gastric cancer cells other hsa-mir-125b-2 Gastric Neoplasms 23128435 MicroRNA-125b expression in gastric adenocarcinoma and its effect on the proliferation of gastric cancer cells other hsa-mir-9-1 Human Immunodeficiency Virus Infection 23129528 The microRNA-9/B-lymphocyte-induced maturation protein-1/IL-2 axis is differentially regulated in progressive HIV infection other hsa-mir-9-2 Human Immunodeficiency Virus Infection 23129528 The microRNA-9/B-lymphocyte-induced maturation protein-1/IL-2 axis is differentially regulated in progressive HIV infection other hsa-mir-21 Lepromatous Leprosy 23134990 "miR-21 and STAT3 are increased in LL lesions with PEH, given their association with epithelial hyperproliferation; and Cbl-b is diminished in LL lesions with PEH compared to classic LL lesions." other hsa-mir-101-1 Pancreatic Neoplasms 23139258 "The good, the bad and the ugly: a tale of miR-101, miR-21 and miR-155 in pancreatic intraductal papillary mucinous neoplasms" other hsa-mir-101-2 Pancreatic Neoplasms 23139258 "The good, the bad and the ugly: a tale of miR-101, miR-21 and miR-155 in pancreatic intraductal papillary mucinous neoplasms" other hsa-mir-155 Pancreatic Neoplasms 23139258 "The good, the bad and the ugly: a tale of miR-101, miR-21 and miR-155 in pancreatic intraductal papillary mucinous neoplasms" other hsa-mir-21 Pancreatic Neoplasms 23139258 "The good, the bad and the ugly: a tale of miR-101, miR-21 and miR-155 in pancreatic intraductal papillary mucinous neoplasms" other hsa-mir-101-1 Systemic Lupus Erythematosus 23139385 "MicroRNA-101, mitogen-activated protein kinases and mitogen-activated protein kinases phosphatase-1 in systemic lupus erythematosus" other hsa-mir-101-2 Systemic Lupus Erythematosus 23139385 "MicroRNA-101, mitogen-activated protein kinases and mitogen-activated protein kinases phosphatase-1 in systemic lupus erythematosus" other hsa-mir-34a Pancreatic Neoplasms 23140286 Genistein Inhibits Cell Growth and Induces Apoptosis Through Up-regulation of miR-34a in Pancreatic Cancer Cell other hsa-mir-29c Nasopharyngeal Neoplasms 23142283 MicroRNA-29c enhances the sensitivities of human nasopharyngeal carcinoma to cisplatin-based chemotherapy and radiotherapy other hsa-mir-1290 Colon Neoplasms 23142292 Up-regulation of microRNA-1290 impairs cytokinesis and affects the reprogramming of colon cancer cells other hsa-mir-326 Lung Neoplasms 23142363 miR-326 associates with biochemical markers of bone turnover in lung cancer bone metastasis other hsa-mir-137 Huntington Disease 23145961 "We also identified several microRNAs (miRNAs) whose aberrant repression is directly mediated by REST, including miR-137, which has not previously been shown to be a direct REST target in mouse." other hsa-mir-96 "Carcinoma, Hepatocellular" 23151657 Inhibition of miR-96 expression reduces cell proliferation and clonogenicity of HepG2 hepatoma cells other hsa-mir-181 Porcine Reproductive and Respiratory Syndrome Virus Infection 23152505 "As expected, miR-181 and other potential PRRSV-targeting miRNAs (such as miR-206) are expressed much more abundantly in minimally permissive cells or tissues than in highly permissive cells or tissues." other hsa-mir-638 Neoplasms [unspecific] 23155245 Expression of human endogenous retrovirus-K coincides with that of micro-RNA-663 and -638 in germ-cell tumor cells other hsa-mir-663a Neoplasms [unspecific] 23155245 Expression of human endogenous retrovirus-K coincides with that of micro-RNA-663 and -638 in germ-cell tumor cells other hsa-mir-663b Neoplasms [unspecific] 23155245 Expression of human endogenous retrovirus-K coincides with that of micro-RNA-663 and -638 in germ-cell tumor cells other hsa-mir-34b Mesothelioma 23155254 MicroRNA miR-34b/c enhances cellular radiosensitivity of malignant pleural mesothelioma cells other hsa-mir-34c Mesothelioma 23155254 MicroRNA miR-34b/c enhances cellular radiosensitivity of malignant pleural mesothelioma cells other hsa-mir-211 Pancreatic Neoplasms 23155457 High-throughput microRNA (miRNAs) arrays unravel the prognostic role of MiR-211 in pancreatic cancer other hsa-mir-199a-1 Melanoma 23162627 Let-7b and microRNA-199a inhibit the proliferation of B16F10 melanoma cells other hsa-mir-199a-2 Melanoma 23162627 Let-7b and microRNA-199a inhibit the proliferation of B16F10 melanoma cells other hsa-mir-99a "Carcinoma, Renal Cell" 23173671 MicroRNA-99a induces G1-phase cell cycle arrest and suppresses tumorigenicity in renal cell carcinoma other hsa-mir-99b "Carcinoma, Renal Cell" 23173671 MicroRNA-99a induces G1-phase cell cycle arrest and suppresses tumorigenicity in renal cell carcinoma other hsa-mir-210 Neoplasms [unspecific] 23173806 "Considering that the exact function of miR-210 is still not well characterized and understood, more investigations should be performed to promote the success of therapeutic-clinical use of miR-210 in cancer" other hsa-mir-29c Neoplasms [unspecific] 23175151 MicroRNA profiling of peripheral nerve sheath tumours identifies miR-29c as a tumour suppressor gene involved in tumour progression other hsa-mir-27a Gastric Neoplasms 23175237 MicroRNA-27a inhibitors alone or in combination with perifosine suppress the growth of gastric cancer cells other hsa-mir-302a Breast Neoplasms 23184229 MicroRNA-302 Replacement Therapy Sensitizes Breast Cancer Cells to Ionizing Radiation other hsa-mir-22 Esophageal Neoplasms 23188185 Increased miRNA-22 expression sensitizes esophageal squamous cell carcinoma to irradiation other hsa-mir-146a Cervical Neoplasms 23189617 "The oncogenic proteins E6, E7 and E5 expressed by HPV directly or indirectly lead to the dysregulation of multiple miRNAs such as miR-34a,miR-218, miR-29a and miR-146a" other hsa-mir-218 Cervical Neoplasms 23189617 "The oncogenic proteins E6, E7 and E5 expressed by HPV directly or indirectly lead to the dysregulation of multiple miRNAs such as miR-34a,miR-218, miR-29a and miR-146a" other hsa-mir-29a Cervical Neoplasms 23189617 "The oncogenic proteins E6, E7 and E5 expressed by HPV directly or indirectly lead to the dysregulation of multiple miRNAs such as miR-34a,miR-218, miR-29a and miR-146a" other hsa-mir-34a Cervical Neoplasms 23189617 "The oncogenic proteins E6, E7 and E5 expressed by HPV directly or indirectly lead to the dysregulation of multiple miRNAs such as miR-34a,miR-218, miR-29a and miR-146a" other hsa-mir-499 Acute Myocardial Infarction 23192357 "The target miRNA is miRNA-499, a biomarker candidate of AMI with low abundance in biological samples. " other hsa-mir-7-1 Neuroblastoma 23192662 Overexpression of miR-7-1 Increases Efficacy of Green Tea Polyphenols for Induction of Apoptosis in Human Malignant Neuroblastoma SH-SY5Y and SK-N-DZ Cells other hsa-mir-7-2 Neuroblastoma 23192662 Overexpression of miR-7-1 Increases Efficacy of Green Tea Polyphenols for Induction of Apoptosis in Human Malignant Neuroblastoma SH-SY5Y and SK-N-DZ Cells other hsa-mir-133b Gastrointestinal Neoplasms 23196799 Fascin-1 overexpression and miR-133b downregulation in the progression of gastrointestinal stromal tumor other hsa-mir-146a Neoplasms [unspecific] 23200854 Epistasis between MicroRNAs 155 and 146a during T Cell-Mediated Antitumor Immunity other hsa-mir-155 Neoplasms [unspecific] 23200854 Epistasis between MicroRNAs 155 and 146a during T Cell-Mediated Antitumor Immunity other hsa-mir-199a-1 Interstitial Cystitis 23201090 miR-199a-5p Regulates Urothelial Permeability and May Play a Role in Bladder Pain Syndrome other hsa-mir-199a-2 Interstitial Cystitis 23201090 miR-199a-5p Regulates Urothelial Permeability and May Play a Role in Bladder Pain Syndrome other hsa-mir-126 Cardiovascular Diseases [unspecific] 23201405 Synergistic induction of miR-126 by hypoxia and HDAC inhibitors in cardiac myocytes other hsa-mir-21 Glioblastoma 23201752 MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma other hsa-mir-146a Myocardial Ischemic-Reperfusion Injury 23208587 Increased expression of microRNA-146a decreases myocardial ischaemia/reperfusion injury other hsa-mir-195 Gastrointestinal Neoplasms 23212612 We demonstrated that miR-195-5p is a novel tumor suppressor miRNA and may contribute to gastric carcinogenesis. other hsa-mir-21 Breast Neoplasms 23216894 Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells other hsa-mir-106a Melanoma 23217102 "Levels of miR-199a were positively correlated and miR-106a negatively correlated with CEC pre-therapy. Decreases in miR-126 and miR-199a and increases in miR-16 and miR-106a were observed after interferon-alfa-2b, but not after dacarbazine." other hsa-mir-126 Melanoma 23217102 "Levels of miR-199a were positively correlated and miR-106a negatively correlated with CEC pre-therapy. Decreases in miR-126 and miR-199a and increases in miR-16 and miR-106a were observed after interferon-alfa-2b, but not after dacarbazine." other hsa-mir-16 Melanoma 23217102 "Levels of miR-199a were positively correlated and miR-106a negatively correlated with CEC pre-therapy. Decreases in miR-126 and miR-199a and increases in miR-16 and miR-106a were observed after interferon-alfa-2b, but not after dacarbazine." other hsa-mir-199a Melanoma 23217102 "Levels of miR-199a were positively correlated and miR-106a negatively correlated with CEC pre-therapy. Decreases in miR-126 and miR-199a and increases in miR-16 and miR-106a were observed after interferon-alfa-2b, but not after dacarbazine." other hsa-mir-122 Hepatitis C Virus Infection 23218444 Can tobacco use promote HCV-induced miR-122 hijacking and hepatocarcinogenesis other hsa-mir-181a-2 Inflammation 23220232 miR-181a and inflammation: miRNA homeostasis response to inflammatory stimuli in vivo other hsa-mir-34a Anemia 23222379 "Thus, in FA patients, increased apoptosis occurs in target epithelial cells of severe aGVHD, and this deleterious effect is linked to overexpression of miR-34a but not TP53." other hsa-mir-21 Inflammatory Bowel Diseases 23224068 PDCD4/miR-21 dysregulation in inflammatory bowel disease-associated carcinogenesis other hsa-mir-449a Hepatitis C Virus Infection 23226395 Hepatitis C Virus Mediated Changes in miRNA-449a Modulates Inflammatory Biomarker YKL40 through Components of the NOTCH Signaling Pathway other hsa-mir-7-1 Breast Neoplasms 23227519 "An induction of microRNA, miR-7 through estrogen treatment in breast carcinoma" other hsa-mir-7-2 Breast Neoplasms 23227519 "An induction of microRNA, miR-7 through estrogen treatment in breast carcinoma" other hsa-mir-7-3 Breast Neoplasms 23227519 "An induction of microRNA, miR-7 through estrogen treatment in breast carcinoma" other hsa-mir-1-1 Osteosarcoma 23229283 miRNA expression profile in human osteosarcoma: Role of miR-1 and miR-133b in proliferation and cell cycle control other hsa-mir-1-2 Osteosarcoma 23229283 miRNA expression profile in human osteosarcoma: Role of miR-1 and miR-133b in proliferation and cell cycle control other hsa-mir-133b Osteosarcoma 23229283 miRNA expression profile in human osteosarcoma: Role of miR-1 and miR-133b in proliferation and cell cycle control other hsa-mir-30d Prostate Neoplasms 23231923 Identification of miR-30d as a novel prognostic maker of prostate cancer other hsa-mir-21 Spinal Cord Injuries 23238710 microRNA-21 Regulates Astrocytic Response Following Spinal Cord Injury other hsa-mir-27a Breast Neoplasms 23240057 MiR-27 as a Prognostic Marker for Breast Cancer Progression and Patient Survival other hsa-mir-27b Breast Neoplasms 23240057 MiR-27 as a Prognostic Marker for Breast Cancer Progression and Patient Survival other hsa-mir-206 Heart Failure 23242657 Recent data indicate that these miRNAs as well as miR-206 change their expression quickly in response to physical activity. other hsa-mir-190a Neuroblastoma 23245204 MiR-190 leads to aggressive phenotype of neuroblastoma through indirect activation of TrkB pathway other hsa-mir-190b Neuroblastoma 23245204 MiR-190 leads to aggressive phenotype of neuroblastoma through indirect activation of TrkB pathway other hsa-mir-122 Hepatitis C Virus Infection 23245472 MicroRNA-122-dependent and -independent replication of Hepatitis C Virus in Hep3B human hepatoma cells other hsa-mir-25 Neoplasms [unspecific] 23246404 Downregulation of the Mitochondrial Calcium Uniporter by Cancer-Related miR-25 other hsa-mir-21 Multiple Myeloma 23247593 "Set9, NF-kB, and microRNA-21 mediate berberine-induced apoptosis of human multiple myeloma cells" other hsa-mir-122 Hepatitis C Virus Infection 23248316 Competing and noncompeting activities of miR-122 and the 5' exonuclease Xrn1 in regulation of hepatitis C virus replication other hsa-let-7i Respiratory Syncytial Virus Pneumonia 23249809 we found that the RSV nonstructural genes NS1 and NS2 antagonized the upregulation of let-7i and miR-30b other hsa-mir-30b Respiratory Syncytial Virus Pneumonia 23249809 we found that the RSV nonstructural genes NS1 and NS2 antagonized the upregulation of let-7i and miR-30b other hsa-mir-196a-1 Breast Neoplasms 23250869 A MicroRNA196a2* and TP63 Circuit Regulated by Estrogen Receptor-alpha and ERK2 that Controls Breast Cancer Proliferation and Invasiveness Properties other hsa-mir-196a-2 Breast Neoplasms 23250869 A MicroRNA196a2* and TP63 Circuit Regulated by Estrogen Receptor-alpha and ERK2 that Controls Breast Cancer Proliferation and Invasiveness Properties other hsa-mir-155 Diabetes Mellitus 23250986 Global Remodeling of the Vascular Stem Cell Niche in Bone Marrow of Diabetic Patients: Implication of the miR-155/FOXO3a Signaling Pathway other hsa-mir-125b-1 Human Immunodeficiency Virus Infection 23251514 Cocaine Enhances HIV-1 Replication in CD4+ T Cells by Down-Regulating MiR-125b other hsa-mir-125b-2 Human Immunodeficiency Virus Infection 23251514 Cocaine Enhances HIV-1 Replication in CD4+ T Cells by Down-Regulating MiR-125b other hsa-mir-182 Glioma 23252827 The miR-183/96/182 Cluster Regulates Oxidative Apoptosis and Sensitizes Cells to Chemotherapy in Gliomas other hsa-mir-183 Glioma 23252827 The miR-183/96/182 Cluster Regulates Oxidative Apoptosis and Sensitizes Cells to Chemotherapy in Gliomas other hsa-mir-96 Glioma 23252827 The miR-183/96/182 Cluster Regulates Oxidative Apoptosis and Sensitizes Cells to Chemotherapy in Gliomas other hsa-mir-29b-1 Multiple Myeloma 23254643 miR-29b negatively regulates human osteoclastic cell differentiation and function: Implications for the treatment of multiple myeloma-related bone disease other hsa-mir-29b-2 Multiple Myeloma 23254643 miR-29b negatively regulates human osteoclastic cell differentiation and function: Implications for the treatment of multiple myeloma-related bone disease other hsa-mir-27a Ovarian Neoplasms 23254909 "The microRNA-27a: ZBTB10-specificity protein pathway is involved in follicle stimulating hormone-induced VEGF, Cox2 and survivin expression in ovarian epithelial cancer cells" other hsa-mir-17 Lung Neoplasms 23263848 miR-17-5p may be potential biomarker for prediction the prognosis in patients with lung cancer. other hsa-mir-146b Thyroid Neoplasms 23264400 Prognostic Implications of miR-146b Expression and Its Functional Role in Papillary Thyroid Carcinoma other hsa-mir-21 Prostate Neoplasms 23272133 Resveratrol Reduces Prostate Cancer Growth and Metastasis by Inhibiting the Akt/MicroRNA-21 Pathway other hsa-mir-194 Breast Neoplasms 23273170 Manipulation of the miR-194 expression level using a synthetic inhibiting RNA produced a small but significant suppression of cell proliferation and upregulation in the expression of several genes that are thought to act as tumor suppressors in MCF-7 and T47D breast cancer cells. other hsa-mir-30d Neoplasms [unspecific] 23274497 mir-30d Regulates multiple genes in the autophagy pathway and impairs autophagy process in human cancer cells other hsa-mir-137 Colorectal Carcinoma 23275153 Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer other hsa-mir-143 Esophageal Neoplasms 23276710 miR-143 may act as a tumor suppressor in ESCC other hsa-mir-18a Rheumatoid Arthritis 23280137 The TNFa-induced miR-18a activates rheumatoid arthritis synovial fibroblasts through a feedback loop in NF-§Ø¨mB signaling other hsa-mir-140 Osteoarthritis 23281373 Detection of the expression level of miR-140 using realtime fluorescent quantitative PCR in knee synovial fluid of osteoarthritis patients other hsa-mir-7-1 Parkinson Disease 23281385 MiR-7 variation is not associated with PD in Chinese patients other hsa-mir-7-2 Parkinson Disease 23281385 MiR-7 variation is not associated with PD in Chinese patients other hsa-mir-7-3 Parkinson Disease 23281385 MiR-7 variation is not associated with PD in Chinese patients other hsa-let-7e "Carcinoma, Hepatocellular" 23282077 "MiR-16, miR-30a, Let-7e and miR-204 were identified as key miRNA regulators contributed to HCC metastasis." other hsa-mir-16 "Carcinoma, Hepatocellular" 23282077 "MiR-16, miR-30a, Let-7e and miR-204 were identified as key miRNA regulators contributed to HCC metastasis." other hsa-mir-204 "Carcinoma, Hepatocellular" 23282077 "MiR-16, miR-30a, Let-7e and miR-204 were identified as key miRNA regulators contributed to HCC metastasis." other hsa-mir-30a "Carcinoma, Hepatocellular" 23282077 "MiR-16, miR-30a, Let-7e and miR-204 were identified as key miRNA regulators contributed to HCC metastasis." other hsa-mir-29a Hepatitis B Virus Infection 23285022 MicroRNA-29a-5p Is a Novel Predictor for Early Recurrence of Hepatitis B Virus-Related Hepatocellular Carcinoma after Surgical Resection other hsa-mir-193b Lymphoma 23288923 "Interestingly, down-regulation of micro-RNAs mmu-miR-30a and mmu-miR-141 as well as hsa-miR-193b clearly contributes to enhance the expression of this gene in mouse and human lymphomas" other hsa-mir-155 Inflammatory Bowel Diseases 23288924 OVER EXPRESSION OF MICRORNAS-155 AND 21 TARGETING MISMATCH REPAIR PROTEINS IN INFLAMMATORY BOWEL DISEASES other hsa-mir-21 Inflammatory Bowel Diseases 23288924 OVER EXPRESSION OF MICRORNAS-155 AND 21 TARGETING MISMATCH REPAIR PROTEINS IN INFLAMMATORY BOWEL DISEASES other hsa-mir-140 Osteoarthritis 23291479 "MiR-146a and -155 were mainly reported for RA, miR-140 was mainly reported for OA including cartilage development." other hsa-mir-146a Rheumatoid Arthritis 23291479 "MiR-146a and -155 were mainly reported for RA, miR-140 was mainly reported for OA including cartilage development." other hsa-mir-155 Rheumatoid Arthritis 23291479 "MiR-146a and -155 were mainly reported for RA, miR-140 was mainly reported for OA including cartilage development." other hsa-mir-34a Neoplasms [unspecific] 23292172 Oncolytic adenovirus co-expressing miRNA-34a and IL-24 induces superior antitumor activity in experimental tumor model other hsa-mir-146a Psychotic Disorders 23295264 Down-regulation of inflammation-protective microRNAs 146a and 212 in monocytes of patients with postpartum psychosis other hsa-mir-212 Psychotic Disorders 23295264 Down-regulation of inflammation-protective microRNAs 146a and 212 in monocytes of patients with postpartum psychosis other hsa-mir-200a Endometrial Neoplasms 23295740 Tamoxifen Represses miR-200 MicroRNAs and Promotes Epithelial-to-Mesenchymal Transition by Up-Regulating c-Myc in Endometrial Carcinoma Cell Lines other hsa-mir-200b Endometrial Neoplasms 23295740 Tamoxifen Represses miR-200 MicroRNAs and Promotes Epithelial-to-Mesenchymal Transition by Up-Regulating c-Myc in Endometrial Carcinoma Cell Lines other hsa-mir-200c Endometrial Neoplasms 23295740 Tamoxifen Represses miR-200 MicroRNAs and Promotes Epithelial-to-Mesenchymal Transition by Up-Regulating c-Myc in Endometrial Carcinoma Cell Lines other hsa-mir-99a Glioblastoma 23298836 The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma other hsa-mir-23b Prostate Neoplasms 23300597 The microRNA -23b/-27b Cluster Suppresses the Metastatic Phenotype of Castration-Resistant Prostate Cancer Cells other hsa-mir-27b Prostate Neoplasms 23300597 The microRNA -23b/-27b Cluster Suppresses the Metastatic Phenotype of Castration-Resistant Prostate Cancer Cells other hsa-mir-138-1 Neoplasms [unspecific] 23300839 MicroRNA-138 Suppresses Neutrophil Gelatinase-Associated Lipocalin Expression and Inhibits Tumorigenicity other hsa-mir-138-2 Neoplasms [unspecific] 23300839 MicroRNA-138 Suppresses Neutrophil Gelatinase-Associated Lipocalin Expression and Inhibits Tumorigenicity other hsa-mir-130a Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients other hsa-mir-155 Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients other hsa-mir-210 Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients other hsa-mir-323a Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients other hsa-mir-323b Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients other hsa-mir-326 Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients other hsa-mir-329-1 Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients other hsa-mir-329-2 Glioblastoma 23302469 Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients other hsa-mir-155 Breast Neoplasms 23302487 "miR-155, as an oncomir, promotes lymph node involvement and vascular invasion and accompanies over-expressed HER-2 on breast cancer FFPE tissue" other hsa-mir-210 Heart Failure 23302636 MicroRNA 210 as a Biomarker for Congestive Heart Failure other hsa-mir-10b Glioblastoma 23307328 Inhibition of miR-10b strongly reduced cell invasion and migration in glioblastoma cell and stem cell lines while overexpression of miR-10b induced cell migration and invasion other hsa-mir-16-1 Colon Neoplasms 23308284 The Induction of microRNA-16 in Colon Cancer Cells by Protein Arginine Deiminase Inhibition Causes a p53-Dependent Cell Cycle Arrest other hsa-mir-16-2 Colon Neoplasms 23308284 The Induction of microRNA-16 in Colon Cancer Cells by Protein Arginine Deiminase Inhibition Causes a p53-Dependent Cell Cycle Arrest other hsa-mir-182 Urinary Bladder Cancer 23313739 MicroRNA-182 plays an onco-miRNA role in cervical cancer other hsa-mir-34b Neoplasms [unspecific] 23314612 MicroRNA-34b functions as a tumor suppressor and acts as a nodal point in the feedback loop with Met other hsa-mir-155 "Carcinoma, Hepatocellular" 23316018 These results suggest that S100A4 exerts its effects through the regulation of miR-155 expression in HCC cells other hsa-mir-30b Vascular Disease [unspecific] 23316327 Bone Morphogenetic Protein-2 Decreases MicroRNA-30b and MicroRNA-30c to Promote Vascular Smooth Muscle Cell Calcification other hsa-mir-30c-1 Vascular Disease [unspecific] 23316327 Bone Morphogenetic Protein-2 Decreases MicroRNA-30b and MicroRNA-30c to Promote Vascular Smooth Muscle Cell Calcification other hsa-mir-30c-2 Vascular Disease [unspecific] 23316327 Bone Morphogenetic Protein-2 Decreases MicroRNA-30b and MicroRNA-30c to Promote Vascular Smooth Muscle Cell Calcification other hsa-mir-200a Breast Neoplasms 23318438 WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells other hsa-mir-200b Breast Neoplasms 23318438 WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells other hsa-mir-200c Breast Neoplasms 23318438 WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells other hsa-mir-143 Prostate Neoplasms 23321517 Mir143 expression inversely correlates with nuclear ERK5 immunoreactivity in clinical prostate cancer other hsa-mir-374a Breast Neoplasms 23321667 MicroRNA-374a activates Wnt/beta-catenin signaling to promote breast cancer metastasis other hsa-mir-126 Atherosclerosis 23324496 whereas the endothelial cell-specific miRNA-126 signals the need for endothelial repair through its transfer from apoptotic endothelial cells in microvesicles other hsa-mir-145 Atherosclerosis 23324496 "Downregulation of miR-145, which controls differentiation of smooth muscle cells, promotes lesion formation" other hsa-mir-155 Atherosclerosis 23324496 Elevated miR-155 levels are characteristic of proinflammatory macrophages and atherosclerotic lesions other hsa-mir-125a Colon Neoplasms 23327190 miR-125a/b Regulates the Activation of Cancer Stem Cells in Paclitaxel-resistant Colon Cancer other hsa-mir-125b-1 Colon Neoplasms 23327190 miR-125a/b Regulates the Activation of Cancer Stem Cells in Paclitaxel-resistant Colon Cancer other hsa-mir-125b-2 Colon Neoplasms 23327190 miR-125a/b Regulates the Activation of Cancer Stem Cells in Paclitaxel-resistant Colon Cancer other hsa-mir-34a Choriocarcinoma 23327670 MiR-34a was either inhibited or ectopically expressed transiently in two choriocarcinoma cell lines (BeWo and JEG-3) respectively. other hsa-mir-708 Breast Neoplasms 23328481 Our findings uncover a mechanistic role for miR-708 in metastasis and provide arationale for developing miR-708 as a therapeutic agent against metastatic breast cancer. other hsa-mir-135b Gastric Neoplasms 23328512 "Quantitative real-time PCR was used to validate the reliability of microarray and detect miR-135b expression in the above clinical samples, as well as cell lines GES-1, BGC-823 and SGC-7901." other hsa-let-7a Pancreatic Neoplasms 23335963 These data demonstrate an intricate post-transcriptional regulation of RRM2 and chemosensitivity by let-7a and that the manipulation of regulatory proteins involved in let-7a transcription/processing may provide a mechanism for improving chemotherapeutic and/or tumor growth control responses in pancreatic cancer. other hsa-mir-199a-1 Breast Neoplasms 23337876 "our data identify miR-199a-5p as a novel and unique regulator of autophagy, which plays an important role in cancer biology and cancer therapy" other hsa-mir-199a-2 Breast Neoplasms 23337876 "our data identify miR-199a-5p as a novel and unique regulator of autophagy, which plays an important role in cancer biology and cancer therapy" other hsa-mir-124 Glioma 23338605 "Luciferase reporter assay confirmed that miR-124, miR-128, miR-146b and miR-218 conferred exogenous gene expression with glioma-specificity." other hsa-mir-128 Glioma 23338605 "Luciferase reporter assay confirmed that miR-124, miR-128, miR-146b and miR-218 conferred exogenous gene expression with glioma-specificity." other hsa-mir-146b Glioma 23338605 "Luciferase reporter assay confirmed that miR-124, miR-128, miR-146b and miR-218 conferred exogenous gene expression with glioma-specificity." other hsa-mir-218 Glioma 23338605 "Luciferase reporter assay confirmed that miR-124, miR-128, miR-146b and miR-218 conferred exogenous gene expression with glioma-specificity." other hsa-mir-23b Breast Neoplasms 23338610 "Pro-oncogenic factors miR-23b- and miR-27b are regulated by Her2/Neu, EGF, and TNFa in breast cancer" other hsa-mir-146a Influenza 23343627 Host microRNA molecular signatures associated with human H1N1 and H3N2 influenza A viruses reveal an unanticipated antiviral activity for miR-146a other hsa-let-7a "Carcinoma, Lung, Non-Small-Cell" 23349018 Expression levels of hsa-let-7a (P = 0.005) and miR-16 (P = 0.003) miRNA were significantly higher in squamous cell carcinoma than in adenocarcinoma samples. other hsa-mir-16 "Carcinoma, Lung, Non-Small-Cell" 23349018 Expression levels of hsa-let-7a (P = 0.005) and miR-16 (P = 0.003) miRNA were significantly higher in squamous cell carcinoma than in adenocarcinoma samples. other hsa-mir-15a Neoplasms [unspecific] 23353574 "Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines" other hsa-mir-21 Prostate Neoplasms 23353719 "miR-21, miR-221 and miR-222 expression and prostate cancer recurrence among obese and non-obese cases" other hsa-mir-221 Prostate Neoplasms 23353719 "miR-21, miR-221 and miR-222 expression and prostate cancer recurrence among obese and non-obese cases" other hsa-mir-222 Prostate Neoplasms 23353719 "miR-21, miR-221 and miR-222 expression and prostate cancer recurrence among obese and non-obese cases" other hsa-mir-29b-1 Neoplasms [unspecific] 23354167 GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression other hsa-mir-29b-2 Neoplasms [unspecific] 23354167 GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression other hsa-mir-199a-1 Neoplasms [unspecific] 23354452 MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines other hsa-mir-199a-2 Neoplasms [unspecific] 23354452 MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines other hsa-mir-199b Neoplasms [unspecific] 23354452 MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines other hsa-mir-92a Immune System Disease [unspecific] 23355465 "we have demonstrated that TLR-mediated miR-92a reduction feedback enhances TLR-triggered production of inflammatory cytokines in macrophages, thus outlining new mechanisms for fine-tuning the TLR-triggered inflammatory response." other hsa-mir-132 Human Immunodeficiency Virus Infection 23357732 miR-132 enhances HIV-1 replication other hsa-mir-18b Melanoma 23365201 The Role of miR-18b in MDM2-p53 Pathway Signaling and Melanoma Progression other hsa-mir-451a Glioblastoma 23367447 "A computational multiscale model of glioblastoma growth: Regulation of cell migration and proliferation via microRNA-451, LKB1 and AMPK" other hsa-mir-221 Osteosarcoma 23372675 MicroRNA-221 Induces Cell Survival and Cisplatin Resistance through PI3K/Akt Pathway in Human Osteosarcoma other hsa-mir-376a-1 Retinoblastoma 23373993 Arsenic trioxide induced apoptosis in retinoblastoma cells by abnormal expression of microRNA-376a other hsa-mir-376a-2 Retinoblastoma 23373993 Arsenic trioxide induced apoptosis in retinoblastoma cells by abnormal expression of microRNA-376a other hsa-mir-7-1 Glioma 23373996 Regulation of Epidermal Growth Factor Receptor Signaling by plasmid-based MicroRNA-7 inhibits human malignant gliomas growth and metastasis in vivo other hsa-mir-7-2 Glioma 23373996 Regulation of Epidermal Growth Factor Receptor Signaling by plasmid-based MicroRNA-7 inhibits human malignant gliomas growth and metastasis in vivo other hsa-mir-7-3 Glioma 23373996 Regulation of Epidermal Growth Factor Receptor Signaling by plasmid-based MicroRNA-7 inhibits human malignant gliomas growth and metastasis in vivo other hsa-mir-143 Glioblastoma 23376635 miR-143 inhibits glycolysis and depletes stemness of glioblastoma stem-like cells other hsa-mir-24 Liver Neoplasms 23382622 "This feedback loop, governed by miR-24 and miR-629, promotes a hepatocyte nuclear factor-4¦Á transient inhibition resulting in miR-124 induction and signal transducer and activator of transcription 3 activation." other hsa-mir-629 Liver Neoplasms 23382622 "This feedback loop, governed by miR-24 and miR-629, promotes a hepatocyte nuclear factor-4¦Á transient inhibition resulting in miR-124 induction and signal transducer and activator of transcription 3 activation." other hsa-mir-210 Myocardial Infarction 23388440 These data demonstrated that a positive feedback loop involving miR-210 and HIF-1¦Á was important for MSC survival under hypoxic conditions. other hsa-mir-200b Prostate Neoplasms 23389960 Down-regulation of miR-200b-3p by low p73 contributes to the androgen-independence of prostate cancer cells other hsa-mir-198 "Carcinoma, Hepatocellular" 23391410 "Control of mitogenic and motogenic pathways by miR-198, diminishing hepatoma cell growth and migration" other hsa-mir-181a-2 Leukemia 23393335 MicroRNA 181a Influences the Expression of HMGB1 and CD4 in Acute Leukemias other hsa-mir-200c Ovarian Neoplasms 23394580 a model for the combined regulatory activity of miR-200c and HuR on TUBB3 expression in ovarian cancer other hsa-mir-126 Breast Neoplasms 23396050 miR-126 and miR-126(*) repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis other hsa-mir-142 Colorectal Carcinoma 23397547 Downregulation of anti-oncomirs miR-143/145 cluster occurs before APC gene aberration in the development of colorectal tumors other hsa-mir-145 Colorectal Carcinoma 23397547 Downregulation of anti-oncomirs miR-143/145 cluster occurs before APC gene aberration in the development of colorectal tumors other hsa-mir-29a Neoplasms [unspecific] 23401122 miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer other hsa-mir-124-1 Melanoma 23404119 miR-124a could function as a potent tumor suppressor in the development of uveal melanoma other hsa-mir-124-2 Melanoma 23404119 miR-124a could function as a potent tumor suppressor in the development of uveal melanoma other hsa-mir-124-3 Melanoma 23404119 miR-124a could function as a potent tumor suppressor in the development of uveal melanoma other hsa-mir-145 Prostate Neoplasms 23404342 Wild-type p53 suppresses the epithelial-mesenchymal transition and stemness in PC-3 prostate cancer cells by modulating miR-145 other hsa-mir-7-1 Glioma 23404538 Poly(amido amine) is an ideal carrier of miR-7 for enhancing gene silencing effects on the EGFR pathway in U251 glioma cells other hsa-mir-7-2 Glioma 23404538 Poly(amido amine) is an ideal carrier of miR-7 for enhancing gene silencing effects on the EGFR pathway in U251 glioma cells other hsa-mir-7-3 Glioma 23404538 Poly(amido amine) is an ideal carrier of miR-7 for enhancing gene silencing effects on the EGFR pathway in U251 glioma cells other hsa-mir-122 Hepatitis C Virus Infection 23405269 microRNA-122 Dependent Binding of Ago2 Protein to Hepatitis C Virus RNA Is Associated with Enhanced RNA Stability and Translation Stimulation other hsa-mir-342 Breast Neoplasms 23408138 miR-342 is associated with estrogen receptor-§Ø©ãexpression and response to tamoxifen in breast cancer other hsa-mir-99a Glioblastoma 23409016 Photofrin Based Photodynamic Therapy and miR-99a Transfection Inhibited FGFR3 and PI3K/Akt Signaling Mechanisms to Control Growth of Human Glioblastoma In Vitro and In Vivo other hsa-mir-133a-1 Urinary Bladder Cancer 23410519 "A Common microRNA Signature Consisting of miR-133a, miR-139-3p, and miR-142-3p Clusters Bladder Carcinoma in Situ With Normal Umbrella Cells" other hsa-mir-139 Urinary Bladder Cancer 23410519 "A Common microRNA Signature Consisting of miR-133a, miR-139-3p, and miR-142-3p Clusters Bladder Carcinoma in Situ With Normal Umbrella Cells" other hsa-mir-142 Urinary Bladder Cancer 23410519 "A Common microRNA Signature Consisting of miR-133a, miR-139-3p, and miR-142-3p Clusters Bladder Carcinoma in Situ With Normal Umbrella Cells" other hsa-mir-106a Glioblastoma 23416698 MiR-106a is an independent prognostic marker in patients with glioblastoma other hsa-mir-146b Glioma 23419525 Intra-tumor injection of exosomes derived from miR-146-expressing MSCs significantly reduced glioma xenograft growth in a rat model of primary brain tumor. other hsa-mir-181c Gastric Neoplasms 23425811 miR-181c expression level was significantly related to several clinicopathological features of gastric cancer other hsa-mir-487b Lung Neoplasms 23426183 Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis other hsa-mir-143 Osteosarcoma 23430952 "These effects were associated with decreased expression of Notch-1 and its downstream genes, such as vascular endothelial growth factor and matrix metalloproteinases, as well as increased expression of a panel of tumor-suppressive microRNAs (miRNAs), including miR-34a, miR-143, miR-145 and miR-200b/c that are typically lost in osteosarcoma. " other hsa-mir-145 Osteosarcoma 23430952 "These effects were associated with decreased expression of Notch-1 and its downstream genes, such as vascular endothelial growth factor and matrix metalloproteinases, as well as increased expression of a panel of tumor-suppressive microRNAs (miRNAs), including miR-34a, miR-143, miR-145 and miR-200b/c that are typically lost in osteosarcoma. " other hsa-mir-200b Osteosarcoma 23430952 "These effects were associated with decreased expression of Notch-1 and its downstream genes, such as vascular endothelial growth factor and matrix metalloproteinases, as well as increased expression of a panel of tumor-suppressive microRNAs (miRNAs), including miR-34a, miR-143, miR-145 and miR-200b/c that are typically lost in osteosarcoma. " other hsa-mir-200c Osteosarcoma 23430952 "These effects were associated with decreased expression of Notch-1 and its downstream genes, such as vascular endothelial growth factor and matrix metalloproteinases, as well as increased expression of a panel of tumor-suppressive microRNAs (miRNAs), including miR-34a, miR-143, miR-145 and miR-200b/c that are typically lost in osteosarcoma. " other hsa-mir-34a Osteosarcoma 23430952 "These effects were associated with decreased expression of Notch-1 and its downstream genes, such as vascular endothelial growth factor and matrix metalloproteinases, as well as increased expression of a panel of tumor-suppressive microRNAs (miRNAs), including miR-34a, miR-143, miR-145 and miR-200b/c that are typically lost in osteosarcoma. " other hsa-mir-125b-1 Neoplasms [unspecific] 23437196 Forced expression of HER2 and HER3 rescued miR-199a- and miR-125b-inhibiting angiogenesis responses and Akt/p70S6K1/HIF-1§Ø©ãpathway. other hsa-mir-125b-2 Neoplasms [unspecific] 23437196 Forced expression of HER2 and HER3 rescued miR-199a- and miR-125b-inhibiting angiogenesis responses and Akt/p70S6K1/HIF-1§Ø©ãpathway. other hsa-mir-199a-1 Neoplasms [unspecific] 23437196 Forced expression of HER2 and HER3 rescued miR-199a- and miR-125b-inhibiting angiogenesis responses and Akt/p70S6K1/HIF-1§Ø©ãpathway. other hsa-mir-199a-2 Neoplasms [unspecific] 23437196 Forced expression of HER2 and HER3 rescued miR-199a- and miR-125b-inhibiting angiogenesis responses and Akt/p70S6K1/HIF-1§Ø©ãpathway. other hsa-mir-18a Colorectal Carcinoma 23437304 MicroRNA-18a Attenuates DNA Damage Repair through Suppressing the Expression of Ataxia Telangiectasia Mutated in Colorectal Cancer other hsa-mir-200a Colorectal Carcinoma 23441132 Down-Regulation of the miRNA-200 Family at the Invasive Front of Colorectal Cancers with Degraded Basement Membrane Indicates EMT Is Involved in Cancer Progression other hsa-mir-200b Colorectal Carcinoma 23441132 Down-Regulation of the miRNA-200 Family at the Invasive Front of Colorectal Cancers with Degraded Basement Membrane Indicates EMT Is Involved in Cancer Progression other hsa-mir-200c Colorectal Carcinoma 23441132 Down-Regulation of the miRNA-200 Family at the Invasive Front of Colorectal Cancers with Degraded Basement Membrane Indicates EMT Is Involved in Cancer Progression other hsa-mir-21 "Carcinoma, Hepatocellular" 23442323 Thyroid hormone regulation of miR-21 enhances migration and invasion of hepatoma other hsa-mir-218-1 Urinary Bladder Cancer 23443110 MiR-218 Impairs Tumor Growth and Increases Chemo-Sensitivity to Cisplatin in Cervical Cancer other hsa-mir-218-2 Urinary Bladder Cancer 23443110 MiR-218 Impairs Tumor Growth and Increases Chemo-Sensitivity to Cisplatin in Cervical Cancer other hsa-mir-138-1 Head And Neck Neoplasms 23445815 Role of microRNA-138 as a Potential Tumor Suppressor in Head and Neck Squamous Cell Carcinoma other hsa-mir-138-2 Head And Neck Neoplasms 23445815 Role of microRNA-138 as a Potential Tumor Suppressor in Head and Neck Squamous Cell Carcinoma other hsa-mir-138 Cholangiocarcinoma 23446431 "Downregulation of microRNA-138 enhances the proliferation, migration and invasion of cholangiocarcinoma cells through the upregulation of RhoC/p-ERK/MMP-2/MMP-9." other hsa-mir-208b Myocardial Infarction 23448306 During surgery miR-208b and miR-499-5p was released in the coronary sinus after cardioplegia-reperfusion to markedly higher levels than in a peripheral vein. other hsa-mir-499 Myocardial Infarction 23448306 During surgery miR-208b and miR-499-5p was released in the coronary sinus after cardioplegia-reperfusion to markedly higher levels than in a peripheral vein. other hsa-mir-195 Tongue Neoplasms 23451060 Prognostic Implications of MicoRNA miR-195 Expression in Human Tongue Squamous Cell Carcinoma other hsa-mir-335 Prostate Neoplasms 23456549 Our data demonstrated for the first time the inhibitory effect of miR-335 on cell proliferation and invasion for PCa cells other hsa-mir-126 Heart Failure 23465244 Expression of miR-126 and miR-508-5p in endothelial progenitor cells is associated with the prognosis of chronic heart failure patients other hsa-mir-508 Heart Failure 23465244 Expression of miR-126 and miR-508-5p in endothelial progenitor cells is associated with the prognosis of chronic heart failure patients other hsa-mir-27a "Carcinoma, Oral" 23472065 Primary Microcephaly Gene MCPH1 Shows Signatures of Tumor Suppressors and Is Regulated by miR-27a in Oral Squamous Cell Carcinoma other hsa-mir-612 "Carcinoma, Hepatocellular" 23478189 miR-612 suppresses the invasive-metastatic cascade in hepatocellular carcinoma other hsa-mir-21 Psoriasis 23479230 Mechanistic studies revealed a P2X7R-dependent mir-21 angiogenesis pathway that leads to the expression of vascular endothelial growth factor and IL-6 and that may be involved in the development of psoriatic lesions. other hsa-mir-221 Multiple Myeloma 23479461 In Vitro and in Vivo Anti-tumor Activity of miR-221/222 Inhibitors in Multiple Myeloma other hsa-mir-222 Multiple Myeloma 23479461 In Vitro and in Vivo Anti-tumor Activity of miR-221/222 Inhibitors in Multiple Myeloma other hsa-mir-584 Breast Neoplasms 23479725 Micro-RNA-584 and the protein phosphatase and actin regulator 1 (PHACTR1): New Signaling Route Through Which Transforming Growth Factor-Beta Mediates the Migration and Actin Dynamics of Breast Cancer Cells other hsa-mir-128-1 Glioblastoma 23482671 "NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200" other hsa-mir-128-2 Glioblastoma 23482671 "NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200" other hsa-mir-200 Glioblastoma 23482671 "NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200" other hsa-mir-21 Glioblastoma 23482671 "NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200" other hsa-mir-101-1 "Carcinoma, Hepatocellular" 23483142 miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells other hsa-mir-101-2 "Carcinoma, Hepatocellular" 23483142 miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells other hsa-mir-132 Epilepsy 23485811 "Functional studies employing antagomirs have identified contributions from miR-34a and miR-132 to seizure-induced neuronal death whereas silencing miR-134 potently reduced status epilepticus, seizure-damage and the later occurrence of spontaneous seizures." other hsa-mir-34a Epilepsy 23485811 "Functional studies employing antagomirs have identified contributions from miR-34a and miR-132 to seizure-induced neuronal death whereas silencing miR-134 potently reduced status epilepticus, seizure-damage and the later occurrence of spontaneous seizures." other hsa-mir-210 Lung Neoplasms 23492775 MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines other hsa-mir-133a Vascular Hypertrophy 23493786 "Our study unraveled for the first time the cardioprotection of choline against cardiac hypertrophy, with correction of expression of miR-133a and calcineurin as a possible mechanism. " other hsa-mir-17 Feingold Syndrome 23495052 De novo 13q31.1-q32.1 interstitial deletion encompassing the miR-17-92 cluster in a patient with Feingold syndrome-2. other hsa-mir-18 Feingold Syndrome 23495052 De novo 13q31.1-q32.1 interstitial deletion encompassing the miR-17-92 cluster in a patient with Feingold syndrome-2. other hsa-mir-19a Feingold Syndrome 23495052 De novo 13q31.1-q32.1 interstitial deletion encompassing the miR-17-92 cluster in a patient with Feingold syndrome-2. other hsa-mir-19b-1 Feingold Syndrome 23495052 De novo 13q31.1-q32.1 interstitial deletion encompassing the miR-17-92 cluster in a patient with Feingold syndrome-2. other hsa-mir-20a Feingold Syndrome 23495052 De novo 13q31.1-q32.1 interstitial deletion encompassing the miR-17-92 cluster in a patient with Feingold syndrome-2. other hsa-mir-92-1 Feingold Syndrome 23495052 De novo 13q31.1-q32.1 interstitial deletion encompassing the miR-17-92 cluster in a patient with Feingold syndrome-2. other hsa-mir-125b-1 Neoplasms [unspecific] 23497288 miR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor other hsa-mir-125b-2 Neoplasms [unspecific] 23497288 miR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor other hsa-mir-133a Arrhythmia 23497314 Multiple miR-133a isomiRs with potential different mRNA target profiles are present in the atrium in humans and mice. other hsa-mir-155 "Leukemia, Myeloid, Acute" 23497456 Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia other hsa-mir-92a-1 Ovarian Neoplasms 23499550 miR-92a Inhibits Peritoneal Dissemination of Ovarian Cancer Cells by Inhibiting Integrin Expression. other hsa-mir-92a-2 Ovarian Neoplasms 23499550 miR-92a Inhibits Peritoneal Dissemination of Ovarian Cancer Cells by Inhibiting Integrin ¦Á5 Expression. other hsa-mir-100 Prostate Neoplasms 23503652 "Tumor suppressor microRNAs, miR-100 and -125b, are regulated by 1,25-dihydroxyvitamin D in primary prostate cells and in patient tissue." other hsa-mir-125b Prostate Neoplasms 23503652 "Tumor suppressor microRNAs, miR-100 and -125b, are regulated by 1,25-dihydroxyvitamin D in primary prostate cells and in patient tissue." other hsa-mir-191 Breast Neoplasms 23505378 Estrogen Mediated-Activation of miR-191/425 Cluster Modulates Tumorigenicity of Breast Cancer Cells Depending on Estrogen Receptor Status other hsa-mir-425 Breast Neoplasms 23505378 Estrogen Mediated-Activation of miR-191/425 Cluster Modulates Tumorigenicity of Breast Cancer Cells Depending on Estrogen Receptor Status other hsa-mir-9-1 Human Immunodeficiency Virus Infection 23508624 Modulation of BK Channel by MicroRNA-9 in Neurons After Exposure to HIV and Methamphetamine other hsa-mir-122 Hepatitis B Virus Infection 23508904 Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B other hsa-mir-22 Hepatitis B Virus Infection 23508904 Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B other hsa-mir-9-1 Leukemia 23509296 a unique role of miR-9 in myelopoiesis and in the pathogenesis of EVI1-induced myeloid neoplasms and provide insights into the epigenetic regulation of miR9 in tumorigenesis other hsa-mir-9-2 Leukemia 23509296 a unique role of miR-9 in myelopoiesis and in the pathogenesis of EVI1-induced myeloid neoplasms and provide insights into the epigenetic regulation of miR9 in tumorigenesis other hsa-mir-9-3 Leukemia 23509296 a unique role of miR-9 in myelopoiesis and in the pathogenesis of EVI1-induced myeloid neoplasms and provide insights into the epigenetic regulation of miR9 in tumorigenesis other hsa-mir-155 Glioblastoma 23512614 "Cytokines (IL-1¦Â and TNF¦Á) also induce the expression of miR-155 and miR-155*, the microRNAs crucial in immunity and inflammation-induced oncogenesis and this is dose-dependently suppressed by IRF3. " other hsa-mir-155 Atherosclerosis 23513069 The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1-and microRNA-155-Dependent Pathway during Atherosclerosis other hsa-mir-342 Atherosclerosis 23513069 The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1-and microRNA-155-Dependent Pathway during Atherosclerosis other hsa-mir-20a "Leukemia, Myeloid, Acute" 23515710 The clinical characteristics and prognostic significance of MN1 gene and MN1-associated microRNA expression in adult patients with de novo acute myeloid leukemia. other hsa-mir-17 Rheumatoid Arthritis 23516027 The miR-17???92 Cluster: A Key Player in the Control of Inflammation during Rheumatoid Arthritis. other hsa-mir-18 Rheumatoid Arthritis 23516027 The miR-17???92 Cluster: A Key Player in the Control of Inflammation during Rheumatoid Arthritis. other hsa-mir-19a Rheumatoid Arthritis 23516027 The miR-17???92 Cluster: A Key Player in the Control of Inflammation during Rheumatoid Arthritis. other hsa-mir-19b-1 Rheumatoid Arthritis 23516027 The miR-17???92 Cluster: A Key Player in the Control of Inflammation during Rheumatoid Arthritis. other hsa-mir-20a Rheumatoid Arthritis 23516027 The miR-17???92 Cluster: A Key Player in the Control of Inflammation during Rheumatoid Arthritis. other hsa-mir-92-1 Rheumatoid Arthritis 23516027 The miR-17???92 Cluster: A Key Player in the Control of Inflammation during Rheumatoid Arthritis. other hsa-mir-125a Breast Neoplasms 23519125 "Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells" other hsa-mir-125b-1 Breast Neoplasms 23519125 "Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells" other hsa-mir-125b-2 Breast Neoplasms 23519125 "Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells" other hsa-mir-205 Breast Neoplasms 23519125 "Functional cooperation of miR-125a, miR-125b, and miR-205 in entinostat-induced downregulation of erbB2/erbB3 and apoptosis in breast cancer cells" other hsa-mir-222 "Leukemia, Acute" 23522449 MicroRNA profiling reveals aberrant microRNA expression in adult ETP-ALL and functional studies implicate a role for miR-222 in acute leukemia other hsa-mir-26a-1 Pituitary Adenoma 23525216 miR-26a Plays an Important Role in Cell Cycle Regulation in ACTH-Secreting Pituitary Adenomas by Modulating Protein Kinase C other hsa-mir-26a-2 Pituitary Adenoma 23525216 miR-26a Plays an Important Role in Cell Cycle Regulation in ACTH-Secreting Pituitary Adenomas by Modulating Protein Kinase C other hsa-mir-34a "Leukemia, Lymphocytic, Chronic, B-Cell" 23525797 Inactivation of TP53 correlates with disease progression and low miR-34a expression in previously treated chronic lymphocytic leukemia patients other hsa-mir-221 Breast Neoplasms 23529451 miR-221/222: promising biomarkers for breast cancer. other hsa-mir-222 Breast Neoplasms 23529451 miR-221/222: promising biomarkers for breast cancer. other hsa-mir-34a Glioma 23529798 These findings indicate the role of miR-34a in tumor progression may be closely associated with p53 mutation and inversely correlated to Bcl-2 expression other hsa-mir-27a Colorectal Carcinoma 23530649 Resveratrol and Quercetin in Combination Have Anticancer Activity in Colon Cancer Cells and Repress Oncogenic microRNA-27a other hsa-mir-215 Colorectal Carcinoma 23532818 MicroRNA-215 inhibits relapse of colorectal cancer patients following radical surgery other hsa-mir-18a Glioma 23533157 Tumorigenic Potential of miR-18A* in Glioma Initiating Cells Requires NOTCH-1 Signaling other hsa-mir-122 Hepatitis C Virus Infection 23537271 Down-regulating miR-122 expression by HCV core protein may give a new insight into the interaction between HCV and miR-122 and chronic HCV infection other hsa-mir-155 Hematologic Neoplasms 23538486 Transfection of Kasumi-1 cells with a new type of polymer carriers loaded with miR-155 and antago-miR-155. other hsa-mir-21 Colon Neoplasms 23544170 Down-regulation of miR-21 Induces Differentiation of Chemoresistant Colon Cancer Cells and Enhances Susceptibility to Therapeutic Regimens other hsa-mir-200c Breast Neoplasms 23546450 miRNA-200c increases the sensitivity of breast cancer cells to doxorubicin through the suppression of E-cadherin-mediated PTEN/Akt signaling other hsa-mir-92 "Carcinoma, Hepatocellular" 23546593 Expression and significance of PTEN and miR-92 in hepatocellular carcinoma other hsa-mir-150 Myocardial Infarction 23547171 MicroRNA-150: A Novel Marker of Left Ventricular Remodeling After Acute Myocardial Infarction other hsa-mir-21 "Lymphoma, B-Cell" 23548551 Inhibition of miR-21 Induces Biological and Behavioral Alterations in Diffuse Large B-Cell Lymphoma other hsa-mir-515-1 Breast Neoplasms 23549953 Involvement of IGF-1R regulation by miR-515-5p modifies breast cancer risk among BRCA1 carriers other hsa-mir-515-2 Breast Neoplasms 23549953 Involvement of IGF-1R regulation by miR-515-5p modifies breast cancer risk among BRCA1 carriers other hsa-mir-181 Leukemia 23550642 We also present observations based on analyzes of miR-181 family genes that indicate the potential functions of primary and/or precursor miRNAs in target recognition and explore the impact of these findings on target identification. other hsa-mir-17 Neoplasms [unspecific] 23550645 "Recent functional dissection of mir-17-92 indicates that individual mir-17-92 components perform distinct biological functions, which collectively regulate multiple related cellular processes during development and disease." other hsa-mir-18 Neoplasms [unspecific] 23550645 "Recent functional dissection of mir-17-92 indicates that individual mir-17-92 components perform distinct biological functions, which collectively regulate multiple related cellular processes during development and disease." other hsa-mir-19a Neoplasms [unspecific] 23550645 "Recent functional dissection of mir-17-92 indicates that individual mir-17-92 components perform distinct biological functions, which collectively regulate multiple related cellular processes during development and disease." other hsa-mir-19b-1 Neoplasms [unspecific] 23550645 "Recent functional dissection of mir-17-92 indicates that individual mir-17-92 components perform distinct biological functions, which collectively regulate multiple related cellular processes during development and disease." other hsa-mir-20a Neoplasms [unspecific] 23550645 "Recent functional dissection of mir-17-92 indicates that individual mir-17-92 components perform distinct biological functions, which collectively regulate multiple related cellular processes during development and disease." other hsa-mir-92-1 Neoplasms [unspecific] 23550645 "Recent functional dissection of mir-17-92 indicates that individual mir-17-92 components perform distinct biological functions, which collectively regulate multiple related cellular processes during development and disease." other hsa-mir-15a "Leukemia, B-Cell" 23551855 "DLEU2, which encodes miR-15a and miR-16-1, was discovered from 13q14 deletion in chronic lymphocytic leukemia, while C13orf25, which encodes six mature miRNA (miR-17, miR-18, miR-19a, miR-19b, miR-20a and miR-92a), was identified from 13q31 amplification in aggressive B-cell lymphomas." other hsa-mir-16-1 "Leukemia, B-Cell" 23551855 "DLEU2, which encodes miR-15a and miR-16-1, was discovered from 13q14 deletion in chronic lymphocytic leukemia, while C13orf25, which encodes six mature miRNA (miR-17, miR-18, miR-19a, miR-19b, miR-20a and miR-92a), was identified from 13q31 amplification in aggressive B-cell lymphomas." other hsa-mir-17 "Leukemia, B-Cell" 23551855 "DLEU2, which encodes miR-15a and miR-16-1, was discovered from 13q14 deletion in chronic lymphocytic leukemia, while C13orf25, which encodes six mature miRNA (miR-17, miR-18, miR-19a, miR-19b, miR-20a and miR-92a), was identified from 13q31 amplification in aggressive B-cell lymphomas." other hsa-mir-18 "Leukemia, B-Cell" 23551855 "DLEU2, which encodes miR-15a and miR-16-1, was discovered from 13q14 deletion in chronic lymphocytic leukemia, while C13orf25, which encodes six mature miRNA (miR-17, miR-18, miR-19a, miR-19b, miR-20a and miR-92a), was identified from 13q31 amplification in aggressive B-cell lymphomas." other hsa-mir-19a "Leukemia, B-Cell" 23551855 "DLEU2, which encodes miR-15a and miR-16-1, was discovered from 13q14 deletion in chronic lymphocytic leukemia, while C13orf25, which encodes six mature miRNA (miR-17, miR-18, miR-19a, miR-19b, miR-20a and miR-92a), was identified from 13q31 amplification in aggressive B-cell lymphomas." other hsa-mir-19b "Leukemia, B-Cell" 23551855 "DLEU2, which encodes miR-15a and miR-16-1, was discovered from 13q14 deletion in chronic lymphocytic leukemia, while C13orf25, which encodes six mature miRNA (miR-17, miR-18, miR-19a, miR-19b, miR-20a and miR-92a), was identified from 13q31 amplification in aggressive B-cell lymphomas." other hsa-mir-20a "Leukemia, B-Cell" 23551855 "DLEU2, which encodes miR-15a and miR-16-1, was discovered from 13q14 deletion in chronic lymphocytic leukemia, while C13orf25, which encodes six mature miRNA (miR-17, miR-18, miR-19a, miR-19b, miR-20a and miR-92a), was identified from 13q31 amplification in aggressive B-cell lymphomas." other hsa-mir-92a "Leukemia, B-Cell" 23551855 "DLEU2, which encodes miR-15a and miR-16-1, was discovered from 13q14 deletion in chronic lymphocytic leukemia, while C13orf25, which encodes six mature miRNA (miR-17, miR-18, miR-19a, miR-19b, miR-20a and miR-92a), was identified from 13q31 amplification in aggressive B-cell lymphomas." other hsa-mir-31 Ovarian Neoplasms 23552883 Downregulation of miRNA-31 induces taxane resistance in ovarian cancer cells through increase of receptor tyrosine kinase MET other hsa-mir-101-1 Human Immunodeficiency Virus Infection 23554480 HIV-1 Tat C Modulates Expression of miRNA-101 to Suppress VE-Cadherin in Human Brain Microvascular Endothelial Cells other hsa-mir-101-2 Human Immunodeficiency Virus Infection 23554480 HIV-1 Tat C Modulates Expression of miRNA-101 to Suppress VE-Cadherin in Human Brain Microvascular Endothelial Cells other hsa-mir-181b Glioma 23554660 MiR-181b suppresses proliferation of and reduces chemoresistance to temozolomide in U87 glioma stem cells. other hsa-mir-1228 Gastric Neoplasms 23554909 Restoration of miR-1228* Expression Suppresses Epithelial-Mesenchymal Transition in Gastric Cancer other hsa-mir-574 Prostate Neoplasms 23554959 Genistein Up-Regulates Tumor Suppressor MicroRNA-574-3p in Prostate Cancer other hsa-mir-221 Human Immunodeficiency Virus Infection 23555914 HIV Tat Induces Expression of ICAM-1 in HUVECs: Implications for miR-221/-222 in HIV-Associated Cardiomyopathy other hsa-mir-222 Human Immunodeficiency Virus Infection 23555914 HIV Tat Induces Expression of ICAM-1 in HUVECs: Implications for miR-221/-222 in HIV-Associated Cardiomyopathy other hsa-mir-146a Lung Neoplasms 23555954 "miR-146a Inhibits Cell Growth, Cell Migration and Induces Apoptosis in Non-Small Cell Lung Cancer Cells" other hsa-mir-155 Diabetes Mellitus 23560074 Bone Marrow Progenitor Cell Therapy-Mediated Paracrine Regulation of Cardiac miRNA-155 Modulates Fibrotic Response in Diabetic Hearts other hsa-let-7c "Adenocarcinoma, Lung" 23562878 "Ectopic let-7c expression increased the in vitro and in vivo chemo- or radiosensitivity of DTX-resistant LAD cells through enhanced apoptosis, reversal of epithelial-to-mesenchymal phenotypes, and inhibition of in vivo metastatic potential via inactivation of Akt phosphorylation, whereas a let-7c inhibitor decreased the chemo- or radiosensitivity of parental cells" other hsa-mir-708 Bladder Neoplasms 23568547 miR-708 promotes the development of bladder carcinoma via direct repression of Caspase-2 other hsa-mir-26 "Carcinoma, Hepatocellular" 23569435 Development of a miR-26 Companion Diagnostic Test for Adjuvant Interferon-alpha Therapy in Hepatocellular Carcinoma other hsa-mir-107 Glioma 23572380 MicroRNA-107 Inhibits U87 Glioma Stem Cells Growth and Invasion other hsa-mir-301a Diabetes Mellitus 23573265 MicroRNA-301a Mediated Regulation of Kv4.2 in Diabetes: Identification of Key Modulators other hsa-mir-143 Colorectal Carcinoma 23574723 MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers other hsa-mir-19b-1 Osteosarcoma 23574781 MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma other hsa-mir-19b-2 Osteosarcoma 23574781 MicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcoma other hsa-mir-345 "Carcinoma, Hepatocellular" 23577194 Hepatitis C Virus Core Protein Down-Regulates p21(Waf1/Cip1) and Inhibits Curcumin-Induced Apoptosis through MicroRNA-345 Targeting in Human Hepatoma Cells other hsa-mir-221 Hepatitis E Virus Infection 23579640 Identification of miR-221 and -222 as important regulators in genotype IV swine hepatitis E virus ORF3-expressing HEK 293 cells other hsa-mir-222 Hepatitis E Virus Infection 23579640 Identification of miR-221 and -222 as important regulators in genotype IV swine hepatitis E virus ORF3-expressing HEK 293 cells other hsa-mir-378 "Leukemia, Myeloid, Acute" 23582927 Overexpression of miR-378 is frequent and may affect treatment outcomes in patients with acute myeloid leukemia. other hsa-mir-223 Colon Neoplasms 23584479 Gain-of-function mutant p53 downregulates miR-223 contributing to chemoresistance of cultured tumor cells. other hsa-let-7a Parkinson Disease 23600457 "Furthermore, the lack of LRRK2 leads to an up-regulation of neuronal differentiation-inducing processes, including the Let-7a pathway." other hsa-mir-17 "Squamous Cell Carcinoma, Oral" 23602254 MicroRNA-17/20a functions to inhibit cell migration and can be used a prognostic marker in oral squamous cell carcinoma. other hsa-mir-20a "Squamous Cell Carcinoma, Oral" 23602254 MicroRNA-17/20a functions to inhibit cell migration and can be used a prognostic marker in oral squamous cell carcinoma. other hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 23608884 Loss of p53 and altered miR15-a/16-1¯ýMCL-1 pathway in CLL: insights from TCL1-Tg:p53(-/-) mouse model and primary human leukemia cells. other hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 23608884 Loss of p53 and altered miR15-a/16-1¯ýMCL-1 pathway in CLL: insights from TCL1-Tg:p53(-/-) mouse model and primary human leukemia cells. other hsa-mir-1 "Carcinoma, Lung, Non-Small-Cell" 23617628 "Interplay between heme oxygenase-1 and miR-378 affects non-small cell lung carcinoma growth, vascularization, and metastasis." other hsa-mir-378 "Carcinoma, Lung, Non-Small-Cell" 23617628 "Interplay between heme oxygenase-1 and miR-378 affects non-small cell lung carcinoma growth, vascularization, and metastasis." other hsa-mir-208a Cardiomegaly 23623871 MiRNA-208a and miRNA-208b are triggered in thyroid hormone-induced cardiac hypertrophy - role of type 1 Angiotensin II receptor (AT1R) on miRNA-208a/¦Á-MHC modulation. other hsa-mir-208b Cardiomegaly 23623871 MiRNA-208a and miRNA-208b are triggered in thyroid hormone-induced cardiac hypertrophy - role of type 1 Angiotensin II receptor (AT1R) on miRNA-208a/¦Á-MHC modulation. other hsa-mir-1 Myocardial Infarction 23625462 MicroRNA-1 enhances the angiogenic differentiation of human cardiomyocyte progenitor cells. other hsa-mir-302a Testicular Germ Cell Tumor 23625774 "Up-regulation of miR-302a significantly increased the sensitivity of NT2 cells to cisplatin by enhancing cisplatin-induced G2/M phase arrest and the subsequent progression to apoptosis.MiR-302a also increased the killing effects of cisplatin by lowering the apoptotic threshold; the same result was also observed in another TGCT-derived cell line, NCCIT." other hsa-mir-378 Cardiomegaly 23625957 MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors. other hsa-mir-221 Breast Neoplasms 23637992 miR-221 promotes tumorigenesis in human triple negative breast cancer cells. other hsa-mir-155 Pancreatic Serous Cystic Neoplasm 23638815 "Upregulation of miR-21, miR-155 and miR-708 was found to occur during IPMN malignant transformation." other hsa-mir-21 Pancreatic Serous Cystic Neoplasm 23638815 "Upregulation of miR-21, miR-155 and miR-708 was found to occur during IPMN malignant transformation." other hsa-mir-708 Pancreatic Serous Cystic Neoplasm 23638815 "Upregulation of miR-21, miR-155 and miR-708 was found to occur during IPMN malignant transformation." other hsa-mir-34a Neuroblastoma 23647235 "using the TANA modified antisense oligonucleotide against miR-34a, intracellular levels of miR-34 can be reduced, and consequently, the expression of its target oncogene V-myc myelocytomatosis viral related oncogene, neuroblastoma derived (MYCN) is enhanced. " other hsa-mir-15a "Carcinoma, Hepatocellular" 23649629 Hepatitis B viral RNA directly mediates down-regulation of the tumor suppressor microRNA miR-15a/miR-16-1 in hepatocytes. other hsa-mir-16-1 "Carcinoma, Hepatocellular" 23649629 Hepatitis B viral RNA directly mediates down-regulation of the tumor suppressor microRNA miR-15a/miR-16-1 in hepatocytes. other hsa-mir-183 Pheochromocytoma 23660872 We demonstrated that miR-183 and/or miR-96 impede NGF-induced differentiation in PC12 cells. other hsa-mir-96 Pheochromocytoma 23660872 We demonstrated that miR-183 and/or miR-96 impede NGF-induced differentiation in PC12 cells. other hsa-mir-19a Colon Neoplasms 23666757 MicroRNA-19a targets tissue factor to inhibit colon cancer cells migration and invasion. other hsa-mir-150 "Carcinoma, Lung, Non-Small-Cell" 23670238 "These findings suggest that miR-150, p53 protein and relevant miRNAs are members of a regulatory network in NSCLC tumorigenesis." other hsa-mir-186 "Carcinoma, Lung, Non-Small-Cell" 23671127 PTTG1 promotes migration and invasion of human non-small cell lung cancer cells and is modulated by miR-186. other hsa-mir-449b Colorectal Carcinoma 23674142 These data suggest that miR-449b plays a tumor-suppressive role in colon cancer stem cells other hsa-mir-103 Pancreatic Neoplasms 23674172 Our study demonstrates that the pathophysiology of HNF1A-MODY is associated with the overexpression of miR-103 and miR-224. other hsa-mir-224 Pancreatic Neoplasms 23674172 Our study demonstrates that the pathophysiology of HNF1A-MODY is associated with the overexpression of miR-103 and miR-224. other hsa-mir-200a Cervical Neoplasms 23679328 MiR-93 and miR-200a are associated with metastasis and invasion of cervical carcinoma. other hsa-mir-93 Cervical Neoplasms 23679328 MiR-93 and miR-200a are associated with metastasis and invasion of cervical carcinoma. other hsa-let-7d "Carcinoma, Hepatocellular" 23682578 "The MC recurrence-related miRNA included let-7d*, miR-328 and miR18a*, which potentially regulate K-ras gene expression. " other hsa-mir-18a "Carcinoma, Hepatocellular" 23682578 "The MC recurrence-related miRNA included let-7d*, miR-328 and miR18a*, which potentially regulate K-ras gene expression. " other hsa-mir-328 "Carcinoma, Hepatocellular" 23682578 "The MC recurrence-related miRNA included let-7d*, miR-328 and miR18a*, which potentially regulate K-ras gene expression. " other hsa-mir-10a "Carcinoma, Thyroid, Medullary" 23685355 Overexpression of miR-10a and miR-375 and downregulation of YAP1 in medullary thyroid carcinoma. other hsa-mir-375 "Carcinoma, Thyroid, Medullary" 23685355 Overexpression of miR-10a and miR-375 and downregulation of YAP1 in medullary thyroid carcinoma. other hsa-mir-16 Lymphoma 23686310 Dysregulation of BMI1 and microRNA-16 collaborate to enhance an anti-apoptotic potential in the side population of refractory mantle cell lymphoma. other hsa-mir-23a "Adenocarcinoma, Gastric" 23688986 "Suppression of miR-23a with ASO-23a obviously inhibited cell growth, colony formation and invasiveness of MGC803 cells and significantly enhanced the cell apoptosis." other hsa-mir-1 Vascular Hypertrophy 23691029 "The synergistic effect of miR-21 and miR-1 were functionally validated for their significant influences on myocardial apoptosis, cardiac hypertrophy and fibrosis." other hsa-mir-21 Vascular Hypertrophy 23691029 "The synergistic effect of miR-21 and miR-1 were functionally validated for their significant influences on myocardial apoptosis, cardiac hypertrophy and fibrosis." other hsa-mir-124 Stroke 23696548 These data demonstrate that p53-mediated neuronal cell death after stroke can be nontranscriptionally regulated by a novel mechanism involving suppression of endogenous cell death inhibitors by miR-124. other hsa-mir-375 Ovarian Neoplasms 23696927 Mir-375 enhances ruthenium-derived compound Rawq01 induced cell death in human ovarian cancer. other hsa-mir-146a Chronic Inflammation 23705069 MicroRNA-146a (miR-146a) is a critical negative regulator of inflammation other hsa-mir-200a "Carcinoma, Lung, Non-Small-Cell" 23708087 The microRNA-200 family targets multiple non-small cell lung cancer prognostic markers in H1299 cells and BEAS-2B cells. other hsa-mir-200b "Carcinoma, Lung, Non-Small-Cell" 23708087 The microRNA-200 family targets multiple non-small cell lung cancer prognostic markers in H1299 cells and BEAS-2B cells. other hsa-mir-197 Hepatitis B Virus Infection 23710316 miR-197 Expression in Peripheral Blood Mononuclear Cells from Hepatitis B Virus-Infected Patients. other hsa-mir-21 Cardiovascular Diseases [unspecific] 23710745 MicroRNA-21 protects cardiomyocytes from tumor necrosis factor-¦Á induced apoptosis in vitro via modulating PTEN/AKT/FOXO3a pathway other hsa-mir-1 Vascular Hypertrophy 23711953 the muscle-specific miR-1 and miR-133 are involved in cardiac development and hypertrophy other hsa-mir-145 Pulmonary Hypertension 23713859 "Other microRNAs, such as miR-145, miR-21 and the miR17/92 cluster, have been associated with the disrupted BMPR2 pathway. " other hsa-mir-17 Pulmonary Hypertension 23713859 "Other microRNAs, such as miR-145, miR-21 and the miR17/92 cluster, have been associated with the disrupted BMPR2 pathway. " other hsa-mir-18 Pulmonary Hypertension 23713859 "Other microRNAs, such as miR-145, miR-21 and the miR17/92 cluster, have been associated with the disrupted BMPR2 pathway. " other hsa-mir-19a Pulmonary Hypertension 23713859 "Other microRNAs, such as miR-145, miR-21 and the miR17/92 cluster, have been associated with the disrupted BMPR2 pathway. " other hsa-mir-19b-1 Pulmonary Hypertension 23713859 "Other microRNAs, such as miR-145, miR-21 and the miR17/92 cluster, have been associated with the disrupted BMPR2 pathway. " other hsa-mir-204 Pulmonary Hypertension 23713859 Recent studies demonstrated the role of miR-204 and miR- 206 in pulmonary artery smooth muscle cell (PASMC) proliferation. other hsa-mir-206 Pulmonary Hypertension 23713859 Recent studies demonstrated the role of miR-204 and miR- 206 in pulmonary artery smooth muscle cell (PASMC) proliferation. other hsa-mir-20a Pulmonary Hypertension 23713859 "Other microRNAs, such as miR-145, miR-21 and the miR17/92 cluster, have been associated with the disrupted BMPR2 pathway. " other hsa-mir-21 Pulmonary Hypertension 23713859 "Other microRNAs, such as miR-145, miR-21 and the miR17/92 cluster, have been associated with the disrupted BMPR2 pathway. " other hsa-mir-92-1 Pulmonary Hypertension 23713859 "Other microRNAs, such as miR-145, miR-21 and the miR17/92 cluster, have been associated with the disrupted BMPR2 pathway. " other hsa-mir-126 Diabetes Mellitus 23713864 Recent studies identified circulating microRNA-126 as a biomarker for myocardial injury and vascular damage in diabetes. other hsa-mir-125b-1 "Carcinoma, Lung, Non-Small-Cell" 23718732 MTA1 promotes the invasion and migration of non-small cell lung cancer cells by downregulating miR-125b. other hsa-mir-125b-2 "Carcinoma, Lung, Non-Small-Cell" 23718732 MTA1 promotes the invasion and migration of non-small cell lung cancer cells by downregulating miR-125b. other hsa-mir-21 Ischemia-Reperfusion Injury 23719532 MiR-21 expression is down-regulated and cell apoptosis is increased in rat myocardium during early ischemia-reperfusion injury. other hsa-mir-34c Osteosarcoma 23720736 MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma. other hsa-mir-34a Bladder Neoplasms 23720881 These findings suggest that the relative low expression of miRNA-34a might be involved in the tumorigenesis of bladder cancer. other hsa-mir-139 Breast Neoplasms 23722663 "Some novel miRNAs without known association to breast cancer were also found, and the putative functions of their PINs were also elucidated. These include miR-139 and miR-383. " other hsa-mir-383 Breast Neoplasms 23722663 "Some novel miRNAs without known association to breast cancer were also found, and the putative functions of their PINs were also elucidated. These include miR-139 and miR-383. " other hsa-let-7f "Diabetes Mellitus, Type 2" 23723366 "let-7f, a microRNA which has been related to endothelial angiogenic function, is found to play key role in TSP-2 increase, but let-7f did not directly interact with TSP-2 mRNA." other hsa-mir-491 "Carcinoma, Hepatocellular" 23725476 MicroRNA-491 is involved in metastasis of hepatocellular carcinoma by inhibitions of matrix metalloproteinase and epithelial to mesenchymal transition. other hsa-mir-148a Influenza 23731466 "QRT-PCR assay and ROC curve analyses revealed that miR-31, miR-29a and miR-148a all had significant potential diagnostic value for critically ill patients infected with H1N1 influenza virus" other hsa-mir-29a Influenza 23731466 "QRT-PCR assay and ROC curve analyses revealed that miR-31, miR-29a and miR-148a all had significant potential diagnostic value for critically ill patients infected with H1N1 influenza virus" other hsa-mir-31 Influenza 23731466 "QRT-PCR assay and ROC curve analyses revealed that miR-31, miR-29a and miR-148a all had significant potential diagnostic value for critically ill patients infected with H1N1 influenza virus" other hsa-mir-485 "Carcinoma, Lung, Non-Small-Cell" 23734217 hsa-mir-485 Prostatic Neoplasms Prostatic Neoplasms Cytotoxic treatment of DU-145 cells enhanced the release of PCS-miRNAs with the exception of miR-485-3p which was retained by surviving cells. other hsa-mir-181a-1 Osteosarcoma 23740615 "MicroRNA 181a improves proliferation and invasion, suppresses apoptosis of osteosarcoma cell." other hsa-mir-181a-2 Osteosarcoma 23740615 "MicroRNA 181a improves proliferation and invasion, suppresses apoptosis of osteosarcoma cell." other hsa-mir-224 "Carcinoma, Hepatocellular" 23741247 miR-224 functions as an onco-miRNA in hepatocellular carcinoma cells by activating AKT signaling. other hsa-mir-199a-1 "Carcinoma, Hepatocellular" 23742776 Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression. other hsa-mir-199a-2 "Carcinoma, Hepatocellular" 23742776 Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression. other hsa-mir-200a Endometrial Neoplasms 23743934 ZEB1 overexpression associated with E-cadherin and microRNA-200 downregulation is characteristic of undifferentiated endometrial carcinoma. other hsa-mir-200b Endometrial Neoplasms 23743934 ZEB1 overexpression associated with E-cadherin and microRNA-200 downregulation is characteristic of undifferentiated endometrial carcinoma. other hsa-mir-200c Endometrial Neoplasms 23743934 ZEB1 overexpression associated with E-cadherin and microRNA-200 downregulation is characteristic of undifferentiated endometrial carcinoma. other hsa-mir-29c Glioma 23744344 Tumor-suppressive effects of miR-29c on gliomas. other hsa-mir-129-1 Colorectal Carcinoma 23744359 miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer. other hsa-mir-129-2 Colorectal Carcinoma 23744359 miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer. other hsa-let-7f-1 Stroke 23745809 "antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo." other hsa-let-7f-2 Stroke 23745809 "antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo." other hsa-mir-1-1 Stroke 23745809 "antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo." other hsa-mir-1-2 Stroke 23745809 "antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo." other hsa-mir-145 Stroke 23745809 "antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo." other hsa-mir-181a-1 Stroke 23745809 "antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo." other hsa-mir-181a-2 Stroke 23745809 "antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo." other hsa-mir-497 Stroke 23745809 "antagomirs to miR-145, -497, -181a, -1 and let-7f have been found to be neuroprotective in vivo." other hsa-mir-96 Pancreatic Neoplasms 23752186 EVI1 oncogene promotes KRAS pathway through suppression of microRNA-96 in pancreatic carcinogenesis. other hsa-mir-140 Breast Neoplasms 23752191 Downregulation of miR-140 promotes cancer stem cell formation in basal-like early stage breast cancer. other hsa-mir-21 Pancreatic Neoplasms 23752880 Endoscopically Acquired Pancreatic Cyst Fluid MicroRNA 21 and 221 Are Associated With Invasive Cancer. other hsa-mir-221 Pancreatic Neoplasms 23752880 Endoscopically Acquired Pancreatic Cyst Fluid MicroRNA 21 and 221 Are Associated With Invasive Cancer. other hsa-mir-708 Glioblastoma 23754151 miR-708 acts as a tumor suppressor in human glioblastoma cells. other hsa-mir-200c "Carcinoma, Renal Cell" 23754305 microRNA-200c modulates the epithelial-to-mesenchymal transition in human renal cell carcinoma metastasis. other hsa-mir-124-1 Cerebral Ischemia 23754622 MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation. other hsa-mir-124-2 Cerebral Ischemia 23754622 MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation. other hsa-mir-146a Sepsis 23756365 Morphine induced exacerbation of sepsis is mediated by tempering endotoxin tolerance through modulation of miR-146a. other hsa-mir-193a Colorectal Carcinoma 23758639 "Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer." other hsa-mir-23a Colorectal Carcinoma 23758639 "Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer." other hsa-mir-338 Colorectal Carcinoma 23758639 "Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer." other hsa-mir-181a-2 Breast Neoplasms 23759567 MicroRNA-181a/b: Novel biomarkers to stratify breast cancer patients for PARPi treatment. other hsa-mir-181b-1 Breast Neoplasms 23759567 MicroRNA-181a/b: Novel biomarkers to stratify breast cancer patients for PARPi treatment. other hsa-mir-181b-2 Breast Neoplasms 23759567 MicroRNA-181a/b: Novel biomarkers to stratify breast cancer patients for PARPi treatment. other hsa-mir-125b-1 Multiple Myeloma 23759586 Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression. other hsa-mir-125b-2 Multiple Myeloma 23759586 Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression. other hsa-mir-17 Polycystic Kidney Disease 23759744 miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. other hsa-mir-18a Polycystic Kidney Disease 23759744 miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. other hsa-mir-19a Polycystic Kidney Disease 23759744 miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. other hsa-mir-19b-1 Polycystic Kidney Disease 23759744 miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. other hsa-mir-20a Polycystic Kidney Disease 23759744 miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. other hsa-mir-92a-1 Polycystic Kidney Disease 23759744 miR-17-92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease. other hsa-mir-200a "Carcinoma, Hepatocellular" 23760980 MicroRNA-200a/b influenced the therapeutic effects of curcumin in hepatocellular carcinoma (HCC) cells. other hsa-mir-200b "Carcinoma, Hepatocellular" 23760980 MicroRNA-200a/b influenced the therapeutic effects of curcumin in hepatocellular carcinoma (HCC) cells. other hsa-mir-99a "Diabetes Mellitus, Type 2" 23762265 Insulin Promotes Glucose Consumption via Regulation of miR-99a/mTOR/PKM2 Pathway. other hsa-mir-155 "Leukemia-Lymphoma, Adult T-Cell" 23762762 Cellular MicroRNA miR-155 has Important Roles in Leukemogenesis by Human T-Cell Leukemia Virus Type 1 Infection. other hsa-mir-18b Nasopharyngeal Neoplasms 23764853 Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma. other hsa-mir-221 Colorectal Carcinoma 23770133 "In metastatic CRC cells, reduced levels of mir-221* and mir-224 increase levels of MBD2, thereby decreasing expression of the metastasis suppressor maspin. Increased activities of mir-221* and mir-224 reduce growth and metastasis of CRC xenograft tumors in mice; these mirs might be developed as therapeutic reagents or biomarkers of CRC progression." other hsa-mir-224 Colorectal Carcinoma 23770133 "In metastatic CRC cells, reduced levels of mir-221* and mir-224 increase levels of MBD2, thereby decreasing expression of the metastasis suppressor maspin. Increased activities of mir-221* and mir-224 reduce growth and metastasis of CRC xenograft tumors in mice; these mirs might be developed as therapeutic reagents or biomarkers of CRC progression." other hsa-mir-768 Melanoma 23770856 Repression of microRNA-768-3p by MEK/ERK signalling contributes to enhanced mRNA translation in human melanoma. other hsa-mir-122 Hepatitis C Virus Infection 23770926 mir-122 and the Hepatitis C RNA genome: more than just stability. other hsa-mir-223 Neoplasms [unspecific] 23772809 "mir-223: infection, inflammation and cancer." other hsa-mir-126 Atherosclerosis 23774505 MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease. other hsa-mir-133 Atherosclerosis 23774505 MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease. other hsa-mir-146 Atherosclerosis 23774505 MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease. other hsa-mir-155 Atherosclerosis 23774505 MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease. other hsa-mir-21 Atherosclerosis 23774505 MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease. other hsa-mir-29 Atherosclerosis 23774505 MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease. other hsa-let-7 Breast Neoplasms 23774803 MicroRNA-profiling in breast- and salivary gland-derived adenoid cystic carcinomas other hsa-let-7 Salivary Gland Neoplasms 23774803 MicroRNA-profiling in breast- and salivary gland-derived adenoid cystic carcinomas other hsa-mir-181a-2 Breast Neoplasms 23774803 MicroRNA-profiling in breast- and salivary gland-derived adenoid cystic carcinomas other hsa-mir-181a-2 Salivary Gland Neoplasms 23774803 MicroRNA-profiling in breast- and salivary gland-derived adenoid cystic carcinomas other hsa-mir-24 Breast Neoplasms 23774803 MicroRNA-profiling in breast- and salivary gland-derived adenoid cystic carcinomas other hsa-mir-24 Salivary Gland Neoplasms 23774803 MicroRNA-profiling in breast- and salivary gland-derived adenoid cystic carcinomas other hsa-mir-155 Pancreatic Neoplasms 23776656 "It is possible that mirNA participates in the pathophysiology of pancreatic cancer, but the current popular methods do not accurately reveal the real-time mirNA function. Thus, this report provided a convenient, accurate, and sensitive approach to mirNA research." other hsa-mir-200b Pancreatic Neoplasms 23776656 "It is possible that mirNA participates in the pathophysiology of pancreatic cancer, but the current popular methods do not accurately reveal the real-time mirNA function. Thus, this report provided a convenient, accurate, and sensitive approach to mirNA research." other hsa-mir-132 Encephalomyelitis 23780851 MicroRNA-132 suppresses autoimmune encephalomyelitis by inducing cholinergic anti-inflammation: a new Ahr-based exploration. other hsa-mir-144 Thyroid Neoplasms 23783103 Almost all microRNAs exhibit isoforms of variable length and potentially distinct function in thyroid tumorigenesis. other hsa-mir-146b Thyroid Neoplasms 23783103 Almost all microRNAs exhibit isoforms of variable length and potentially distinct function in thyroid tumorigenesis. other hsa-mir-221 Thyroid Neoplasms 23783103 Almost all microRNAs exhibit isoforms of variable length and potentially distinct function in thyroid tumorigenesis. other hsa-mir-486 Thyroid Neoplasms 23783103 Almost all microRNAs exhibit isoforms of variable length and potentially distinct function in thyroid tumorigenesis. other hsa-mir-551b Thyroid Neoplasms 23783103 Almost all microRNAs exhibit isoforms of variable length and potentially distinct function in thyroid tumorigenesis. other hsa-mir-7 Thyroid Neoplasms 23783103 Almost all microRNAs exhibit isoforms of variable length and potentially distinct function in thyroid tumorigenesis. other hsa-mir-21 Neoplasms [unspecific] 23784029 MiR-21/Smad 7 signaling determines TGF-¦Â1-induced CAF formation. other hsa-mir-22 Gastric Neoplasms 23786758 Reduced expression of miR-22 in gastric cancer is related to clinicopathologic characteristics or patient prognosis.. other hsa-mir-30a "Carcinoma, Ovarian, Serous" 23787480 miRNA expression pattern associated with prognosis in elderly patients with advanced OPSC and OCC. other hsa-mir-30e "Carcinoma, Ovarian, Serous" 23787480 miRNA expression pattern associated with prognosis in elderly patients with advanced OPSC and OCC. other hsa-mir-505 "Carcinoma, Ovarian, Serous" 23787480 miRNA expression pattern associated with prognosis in elderly patients with advanced OPSC and OCC. other hsa-mir-21 Colorectal Carcinoma 23788041 Pleiotropic actions of miR-21 highlight the critical role of deregulated stromal microRNAs during colorectal cancer progression. other hsa-mir-217 "Carcinoma, Renal Cell, Clear-Cell" 23790169 miR-217 plays a tumor suppressor role in ccRCC. other hsa-mir-122 "Carcinoma, Breast" 23791885 MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention. other hsa-mir-127 "Carcinoma, Breast" 23791885 MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention. other hsa-mir-182 "Carcinoma, Breast" 23791885 MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention. other hsa-mir-183 "Carcinoma, Breast" 23791885 MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention. other hsa-mir-206 "Carcinoma, Breast" 23791885 MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention. other hsa-mir-375 "Carcinoma, Breast" 23791885 MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention. other hsa-mir-122 Hepatitis C Virus Infection 23793894 A miRNA-responsive cell-free translation system facilitates isolation of hepatitis C virus miRNP complexes. other hsa-mir-7 "Carcinoma, Renal Cell" 23793934 Identification of miR-7 as an oncogene in renal cell carcinoma. other hsa-mir-146a Neoplasms [unspecific] 23796062 "Our results indicated that ectopic expression of miR-146a could not independently induce differentiation in lymphoblastic cells. However, the expression of multiple genes involved in T-cell differentiation and T-cell CD markers were found to be affected. These results have suggested a potential tumor suppressive, immunomodulatory and cell activator role for miR146-a." other hsa-mir-125b Neoplasms [unspecific] 23800395 The expression and regulation of microRNA-125b in cancers. other hsa-mir-153 Breast Neoplasms 23803066 miR-153 silencing induces apoptosis in the MDA-MB-231 breast cancer cell line. other hsa-mir-17 Lesch-Nyhan Syndrome 23804752 Deficiency of the purine metabolic gene HPRT dysregulates microRNA-17 family cluster and guanine-based cellular functions: a role for EPAC in Lesch-Nyhan syndrome. other hsa-mir-335 Neuroblastoma 23806264 "We report, for the first time, that GRP-R-mediated tumorigenicity and increased metastatic potential in neuroblastoma are regulated, in part, by miR-335 and miR-363. A better understanding of the anti-tumor functions of miRNAs could provide valuable insights to discerning molecular mechanisms responsible for neuroblastoma metastasis." other hsa-mir-363 Neuroblastoma 23806264 "We report, for the first time, that GRP-R-mediated tumorigenicity and increased metastatic potential in neuroblastoma are regulated, in part, by miR-335 and miR-363. A better understanding of the anti-tumor functions of miRNAs could provide valuable insights to discerning molecular mechanisms responsible for neuroblastoma metastasis." other hsa-mir-200c Neoplasms [unspecific] 23806972 Targeted delivery of miR-200c/DOC to inhibit cancer stem cells and cancer cells by the gelatinases-stimuli nanoparticles. other hsa-mir-122 Chronic Hepatitis C 23808991 Serum microRNA-122 kinetics in patients with chronic hepatitis C virus infection during antiviral therapy. other hsa-mir-181b Glioma 23810250 Involvement of FOS-mediated miR-181b/miR-21 signalling in the progression of malignant gliomas. other hsa-mir-21 Glioma 23810250 Involvement of FOS-mediated miR-181b/miR-21 signalling in the progression of malignant gliomas. other hsa-mir-196a Huntington Disease 23810380 "miR-196a ameliorates phenotypes of Huntington disease in cell, transgenic mouse, and induced pluripotent stem cell models." other hsa-mir-126 Coxsackievirus Infection 23811937 MiR-126 promotes coxsackievirus replication by mediating cross-talk of ERK1/2 and Wnt/¦Â-catenin signal pathways. other hsa-mir-21 Neoplasms [unspecific] 23811941 "AC1MMYR2, an inhibitor of dicer-mediated biogenesis of Oncomir miR-21, reverses epithelial-mesenchymal transition and suppresses tumor growth and progression." other hsa-mir-203 Glioma 23813496 "Our data validate an important clinical significance of miR-203 in gliomas, and reveal that it might be an intrinsic regulator of tumor progression and a potential prognostic factor for this dismal disease." other hsa-mir-145 Glioblastoma 23814265 "Our study demonstrates that miR-145 has a tumor-suppressive function in glioblastoma in that it reduces proliferation, adhesion, and invasion of glioblastoma cells, apparently by suppressing the activity of oncogenic proteins Sox9 and ADD3. Reduced levels of miR-145 may lead to neoplastic transformation and malignant progression in glioma due to unregulated activity of these proteins." other hsa-mir-223 "Leukemia, Lymphoblastic" 23815897 Expression of microRNA-223 in lymphocytic leukemia cells and its action mechanism other hsa-mir-155 Lymphoma 23815945 Influence of miRNA-155 on lymphoma. other hsa-mir-155 Hematologic Neoplasms 23815946 Relationship between microRNA-155 and hematological malignancies other hsa-mir-381 Kidney Neoplasms 23816136 miR-381 increases sensitivity of 786-O cells to 5-FU by inhibitory WEE1 and increase of Cdc2 activity. other hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 23817461 This meta-analysis provides evidence that miR-21 and miR-155 are predicting factors for non-small-cell lung cancer prognosis and lymphoid infiltration. other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 23817461 This meta-analysis provides evidence that miR-21 and miR-155 are predicting factors for non-small-cell lung cancer prognosis and lymphoid infiltration. other hsa-mir-30a Hypertension 23817492 miR-30a regulates endothelial tip cell formation and arteriolar branching. other hsa-mir-155 Pancreatic Neoplasms 23817566 Regulation of miR-155 affects pancreatic cancer cell invasiveness and migration by modulating the STAT3 signaling pathway through SOCS1. other hsa-mir-20a "Carcinoma, Cervical" 23819812 Our results suggested that the circulating miR-20a may be a potential biomarker for detecting the lymph node status of cervical cancer patients. other hsa-mir-302c Neoplasms [unspecific] 23820258 "1,25(OH)2D3 facilitates the immuno-attack of NK cells against malignant cells partly through downregulation of miR-302c and miR-520c and hence upregulation of the NKG2D ligands MICA/B and ULBP2." other hsa-mir-520c Neoplasms [unspecific] 23820258 "1,25(OH)2D3 facilitates the immuno-attack of NK cells against malignant cells partly through downregulation of miR-302c and miR-520c and hence upregulation of the NKG2D ligands MICA/B and ULBP2." other hsa-let-7g "Carcinoma, Lung, Non-Small-Cell" 23820752 Let-7g and miR-21 expression in non-small cell lung cancer: correlation with clinicopathological and molecular features other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 23820752 Let-7g and miR-21 expression in non-small cell lung cancer: correlation with clinicopathological and molecular features other hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 23821659 Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia. other hsa-mir-200c Lung Neoplasms 23824089 NF-¦ÊB-mediated inflammation leading to EMT via miR-200c is involved in cell transformation induced by cigarette smoke extract. other hsa-mir-29a Salmonellosis 23826261 "Our study outlines for the first time important regulation pathways in intestinal Salmonella infection pointing out that focal adhesion and organisation of actin cytoskeleton are regulated by microRNAs. Functional relevance is shown by miR-29a mediated Caveolin 2 regulation, modulating the activation state of CDC42. Further analysis of examined interactions may support the discovery of novel strategies impairing the uptake of intracellular pathogens." other hsa-mir-122 Hepatitis C Virus Infection 23826300 Modulation of hepatitis C virus RNA accumulation and translation by DDX6 and miR-122 are mediated by separate mechanisms. other hsa-mir-25 "Squamous Cell Carcinoma, Tongue" 23827155 MiR-25-3p attenuates the proliferation of tongue squamous cell carcinoma cell line Tca8113. other hsa-mir-155 Atherosclerosis 23827206 MicroRNA-155 in the pathogenesis of atherosclerosis other hsa-mir-21 "Carcinoma, Colon" 23827854 Aldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expression. other hsa-mir-1 Mesothelioma 23828229 miR-1 induces growth arrest and apoptosis in malignant mesothelioma. other hsa-mir-34 Neoplasms [unspecific] 23834144 Functional role of miR-34 family in human cancer. other hsa-mir-145 Pancreatic Neoplasms 23834149 "insulingrowth factor-1 receptor expression (miR-7, miR-139, miR-145, miR-1); " other hsa-mir-125 Glioblastoma 23835866 MicroRNA-125b inhibitor sensitizes human primary glioblastoma cells to chemotherapeutic drug temozolomide on invasion. other hsa-mir-34a Neoplasms [unspecific] 23836017 TP53-independent function of miR-34a via HDAC1 and p21(CIP1/WAF1.). other hsa-mir-24 Hypertension 23836801 MicroRNA-24 is a novel regulator of aldosterone and cortisol production in the human adrenal cortex. other hsa-mir-208 Heart Failure 23839576 "Heart function has been restored in rodents by reprogramming non-myocytes into cardiomyocytes, by expressing transcription factors (GATA4, HAND2, myocyte-specific enhancer factor 2C (MEF2C) and T-box 5 (TBX5)) and microRNAs (miR-1, miR-133, miR-208 and miR-499) that control cardiomyocyte identity." other hsa-mir-1234 "Lymphoma, Large B-Cell, Diffuse" 23841503 Expression of microRNA-1234 related signal transducer and activator of transcription 3 in patients with diffuse large B-cell lymphoma of activated B-cell like type from high and low infectious disease areas. other hsa-mir-148a "Carcinoma, Lung, Non-Small-Cell" 23843100 Decreased miRNA-148a is associated with lymph node metastasis and poor clinical outcomes and functions as a suppressor of tumor metastasis in non-small cell lung cancer. other hsa-mir-142 Testicular Germ Cell Tumor 23843459 Tumor-suppressive function of protein-tyrosine phosphatase non-receptor type 23 in testicular germ cell tumors is lost upon overexpression of miR142-3p microRNA. other hsa-mir-302b Osteosarcoma 23845851 Epirubicin-mediated expression of miR-302b is involved in osteosarcoma apoptosis and cell cycle regulation. other hsa-mir-21 Breast Neoplasms 23851508 The anti-metastatic activity of collagenase-2 in breast cancer cells is mediated by a signaling pathway involving decorin and miR-21. other hsa-mir-29 Neoplasms [unspecific] 23857059 miR-29 represses the activities of DNA methyltransferases and DNA demethylases. other hsa-mir-200 "Carcinoma, Hepatocellular" 23857252 MicroRNA/gene profiling unveils early molecular changes and nuclear factor erythroid related factor 2 (NRF2) activation in a rat model recapitulating human hepatocellular carcinoma (HCC). other hsa-mir-21 Lung Neoplasms 23857284 Expression and significance of miRNA-21 and BTG2 in lung cancer. other hsa-mir-133a Muscle Diseases [unspecific] 23858090 miRNA analysis for the assessment of exercise and amino acid effects on human skeletal muscle. other hsa-mir-133b Muscle Diseases [unspecific] 23858090 miRNA analysis for the assessment of exercise and amino acid effects on human skeletal muscle. other hsa-mir-206 Muscle Diseases [unspecific] 23858090 miRNA analysis for the assessment of exercise and amino acid effects on human skeletal muscle. other hsa-mir-499 Muscle Diseases [unspecific] 23858090 miRNA analysis for the assessment of exercise and amino acid effects on human skeletal muscle. other hsa-mir-21 Colorectal Carcinoma 23858763 Construction of microRNA-21 and PTEN eukaryotic expression and short hairpin RNA expression vectors other hsa-mir-1 Vascular Hypertrophy 23859766 "In addition, microRNAs (miR) -133a, miR-208 and miR-1 which were elevated following high-fat feeding were attenuated by apelin treatment." other hsa-mir-208 Vascular Hypertrophy 23859766 "In addition, microRNAs (miR) -133a, miR-208 and miR-1 which were elevated following high-fat feeding were attenuated by apelin treatment." other hsa-mir-124 Stroke 23860031 We highlight interactions between the miR-124 and the miR17-92 cluster and the Notch and Sonic hedgehog signaling pathways in mediating stroke-induced neurogenesis. other hsa-mir-625 Colorectal Carcinoma 23861214 Our results suggest that miR-625 may serve as an efficient clinical biomarker and a therapeutic tool for the inhibition of metastasis in CRC. other hsa-mir-148a "Carcinoma, Hepatocellular" 23861222 Inhibitions of epithelial to mesenchymal transition and cancer stem cells-like properties are involved in miR-148a-mediated anti-metastasis of hepatocellular carcinoma. other hsa-mir-190 Neoplasms [unspecific] 23863200 Transcriptional changes induced by the tumor dormancy-associated microRNA-190. other hsa-mir-143 Colorectal Carcinoma 23866094 miR-143 blocks the TLR2 signalling pathway in human CRC cells. This knowledge may pave the way for new clinical applications utilising miR-143 mimics in the treatment of patients with CRC. other hsa-mir-221 Obesity 23867206 Our results support the link between miR-221 and obesity development as well as obesity related inflammatory status. other hsa-mir-148a Gastric Neoplasms 23869555 Quantitative proteomics reveals diverse roles of miR-148a from gastric cancer progression to neurological development. other hsa-mir-29b "Aortic Aneurysm, Abdominal" 23871588 MicroRNA-29b regulation of abdominal aortic aneurysm development. other hsa-mir-499 Acute Myocardial Infarction 23872321 We developed a novel reverse-transcription real-time PCR assay for human miR-499 quantification. The good reproducibility and wide linearity range may permit more use of it in the quantification of other human miRNAs in future. other hsa-mir-148a Gastric Neoplasms 23873106 microRNA-148a suppresses human gastric cancer cell metastasis by reversing epithelial-to-mesenchymal transition. other hsa-mir-145 Microvascular Disease 23875242 The role of miR-145 in microvasculature. other hsa-mir-365 Schizophrenia 23876895 "This study analyzed possible circulating miRNAs in response to antipsychotic monotherapy for schizophrenia, the further mechanism need to be confirmed." other hsa-let-7c Lung Neoplasms 23880305 "Additionally, antrocin increased microRNA let-7c expression and suppressed STAT signaling." other hsa-mir-127 Gastric Neoplasms 23880861 The Tumor Suppressor Roles of miR-433 and miR-127 in Gastric Cancer. other hsa-mir-433 Gastric Neoplasms 23880861 The Tumor Suppressor Roles of miR-433 and miR-127 in Gastric Cancer. other hsa-mir-122 Hepatitis C Virus Infection 23881584 miR-122 promotion of the hepatitis C virus life cycle: sound in the silence. other hsa-mir-497 Prostate Neoplasms 23886135 MicroRNA-497 suppresses proliferation and induces apoptosis in prostate cancer cells. other hsa-mir-485 "Carcinoma, Breast" 23886178 miR-485 acts as a tumor suppressor by inhibiting cell growth and migration in breast carcinoma T47D cells. other hsa-mir-146a "Leukemia, Lymphoblastic, Acute" 23888320 A functional polymorphism in the miR-146a gene is associated with the risk of childhood acute lymphoblastic leukemia: a preliminary report. other hsa-mir-200a Ovarian Neoplasms 23888941 The biphasic expression pattern of miR-200a and E-cadherin in epithelial ovarian cancer and its correlation with clinicopathological features. other hsa-mir-99a "Adenocarcinoma, Lung" 23893385 Clinic significance of microRNA-99a expression in human lung adenocarcinoma. other hsa-mir-30b "Scleroderma, Systemic" 23893664 Down-regulation of miR-30b might be involved in the pathogenesis of SSc. other hsa-mir-92a Ischemia-Reperfusion Injury 23897866 Inhibition of microRNA-92a protects against ischemia/reperfusion injury in a large-animal model. other hsa-mir-143 "Adenocarcinoma, Gastric" 23898078 Differential miRNA expression patterns of gastric adenocarcinoma of the same histopathology from a small geographic region's population show homogenous correlations with the existence of common risk factors. other hsa-mir-203 "Adenocarcinoma, Gastric" 23898078 Differential miRNA expression patterns of gastric adenocarcinoma of the same histopathology from a small geographic region's population show homogenous correlations with the existence of common risk factors. other hsa-mir-205 "Adenocarcinoma, Gastric" 23898078 Differential miRNA expression patterns of gastric adenocarcinoma of the same histopathology from a small geographic region's population show homogenous correlations with the existence of common risk factors. other hsa-mir-21 "Adenocarcinoma, Gastric" 23898078 Differential miRNA expression patterns of gastric adenocarcinoma of the same histopathology from a small geographic region's population show homogenous correlations with the existence of common risk factors. other hsa-mir-223 "Adenocarcinoma, Gastric" 23898078 Differential miRNA expression patterns of gastric adenocarcinoma of the same histopathology from a small geographic region's population show homogenous correlations with the existence of common risk factors. other hsa-mir-34a "Adenocarcinoma, Gastric" 23898078 Differential miRNA expression patterns of gastric adenocarcinoma of the same histopathology from a small geographic region's population show homogenous correlations with the existence of common risk factors. other hsa-mir-93 "Adenocarcinoma, Gastric" 23898078 Differential miRNA expression patterns of gastric adenocarcinoma of the same histopathology from a small geographic region's population show homogenous correlations with the existence of common risk factors. other hsa-mir-29a Pancreatic Neoplasms 23900458 MicroRNA-29a induces resistance to gemcitabine through the Wnt/¦Â-catenin signaling pathway in pancreatic cancer cells. other hsa-mir-29 Neoplasms [unspecific] 23901138 miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR. other hsa-mir-210 "Carcinoma, Renal Cell" 23902947 "VHL, involved in tumorigenesis of PGLs and clear cell renal cell carcinomas, may be an important player in the pathogenesis of sporadic HNPGLs via activation of an HIF-1¦Á/miR-210 pHx pathway." other hsa-mir-29 Ovarian Neoplasms 23904094 Downregulation of miR-29 contributes to cisplatin resistance of ovarian cancer cells. other hsa-mir-21 Glioblastoma 23907387 "Furthermore, several modules associated with less well-reported molecular aberrations-such as chromosome 11 CNVs, CD40, PLXNB1 and GSTM1 methylations, and mir-21 expressions-were also validated by external information. " other hsa-mir-100 Bladder Neoplasms 23911686 Aberrations in miR expression identified between non-muscle invasive BC and muscle-invasive BC provide insight into the molecular alterations known to distinguish the two parallel pathways of bladder carcinogenesis. The heterogeneity of tumor specimens and research methods limits the reproducibility of changes in miR expression profiles between studies and underscores theimportance of in vivo validation in a field that utilizes in silico miR target-prediction models. other hsa-mir-101 Bladder Neoplasms 23911686 Aberrations in miR expression identified between non-muscle invasive BC and muscle-invasive BC provide insight into the molecular alterations known to distinguish the two parallel pathways of bladder carcinogenesis. The heterogeneity of tumor specimens and research methods limits the reproducibility of changes in miR expression profiles between studies and underscores theimportance of in vivo validation in a field that utilizes in silico miR target-prediction models. other hsa-mir-145 Bladder Neoplasms 23911686 Aberrations in miR expression identified between non-muscle invasive BC and muscle-invasive BC provide insight into the molecular alterations known to distinguish the two parallel pathways of bladder carcinogenesis. The heterogeneity of tumor specimens and research methods limits the reproducibility of changes in miR expression profiles between studies and underscores theimportance of in vivo validation in a field that utilizes in silico miR target-prediction models. other hsa-mir-21 Bladder Neoplasms 23911686 Aberrations in miR expression identified between non-muscle invasive BC and muscle-invasive BC provide insight into the molecular alterations known to distinguish the two parallel pathways of bladder carcinogenesis. The heterogeneity of tumor specimens and research methods limits the reproducibility of changes in miR expression profiles between studies and underscores theimportance of in vivo validation in a field that utilizes in silico miR target-prediction models. other hsa-mir-373 Bladder Neoplasms 23911686 Aberrations in miR expression identified between non-muscle invasive BC and muscle-invasive BC provide insight into the molecular alterations known to distinguish the two parallel pathways of bladder carcinogenesis. The heterogeneity of tumor specimens and research methods limits the reproducibility of changes in miR expression profiles between studies and underscores theimportance of in vivo validation in a field that utilizes in silico miR target-prediction models. other hsa-mir-99a Bladder Neoplasms 23911686 Aberrations in miR expression identified between non-muscle invasive BC and muscle-invasive BC provide insight into the molecular alterations known to distinguish the two parallel pathways of bladder carcinogenesis. The heterogeneity of tumor specimens and research methods limits the reproducibility of changes in miR expression profiles between studies and underscores theimportance of in vivo validation in a field that utilizes in silico miR target-prediction models. other hsa-mir-106b "Carcinoma, Laryngeal" 23912048 MicroRNA-106b regulates the tumor suppressor RUNX3 in laryngeal carcinoma cells. other hsa-mir-17 "Carcinoma, Hepatocellular" 23912452 Thyroid hormone receptor represses miR-17 expression to enhance tumor metastasis in human hepatoma cells. other hsa-mir-31 Chordoma 23912551 MicroRNA expression profiling reveals the potential function of microRNA-31 in chordomas. other hsa-mir-224 "Carcinoma, Hepatocellular" 23913306 "A noncanonical pathway links autophagy,miR-224, Smad4, and HBV-associated HCC. These findings open a new avenue for the treatment of HCC." other hsa-mir-100 "Leukemia, Lymphoblastic, Acute" 23915977 "MiR-125b, miR-100 and miR-99a co-regulate vincristine resistance in childhood acute lymphoblastic leukemia." other hsa-mir-125b "Leukemia, Lymphoblastic, Acute" 23915977 "MiR-125b, miR-100 and miR-99a co-regulate vincristine resistance in childhood acute lymphoblastic leukemia." other hsa-mir-99a "Leukemia, Lymphoblastic, Acute" 23915977 "MiR-125b, miR-100 and miR-99a co-regulate vincristine resistance in childhood acute lymphoblastic leukemia." other hsa-mir-34c Neoplasms [unspecific] 23922103 These findings provide a novel molecular mechanism of MET regulation in PCa and contribute to the increasing evidence that miR-34c has a key tumour suppressive role in PCa. other hsa-mir-768 Lung Neoplasms 23928793 The brain microenvironment negatively regulates miRNA-768-3p to promote K-ras expression and lung cancer metastasis. other hsa-mir-515 Breast Neoplasms 23928990 Downregulation of microRNA-515-5p by the estrogen receptor modulates sphingosine kinase 1 and breast cancer cell proliferation. other hsa-mir-148a Colorectal Carcinoma 23933284 Clinical significance of microRNA-148a in patients with early relapse of stage II stage and III colorectal cancer after curative resection. other hsa-mir-192 Influenza 23934176 MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies. other hsa-mir-24 Multiple Myeloma 23934711 Contribution of microRNA 24-3p and Erk1/2 to interleukin-6 mediated plasma cell survival. other hsa-mir-202 Gastric Neoplasms 23936094 "Decrease of miR-202-3p expression, a novel tumor suppressor, in gastric cancer." other hsa-mir-140 Osteoarthritis 23942573 Molecular mechanisms of the cartilage-specific microRNA-140 in osteoarthritis. other hsa-mir-29c Glioma 23943502 "MiR-29c inhibits glioma cell proliferation, migration, invasion and angiogenesis." other hsa-mir-221 Asthma 23944957 Airway smooth muscle hyperproliferation is regulated by microRNA-221 in severe asthma. other hsa-mir-100 Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. other hsa-mir-29c Multiple Sclerosis 23946286 MicroRNA-29c in urinary exosome/microvesicle as a biomarker of renal fibrosis. other hsa-mir-186 "Carcinoma, Endometrioid Endometrial" 23946815 "The qRT-PCR analysis further identified a profile of four serum miRNAs (miR-222, miR-223, miR-186 and miR-204) as a fingerprint for EEC detection." other hsa-mir-155 Immune System Disease [unspecific] 23949802 MicroRNA-155 drives TH17 immune response and tissue injury in experimental crescentic GN. other hsa-mir-153 Colorectal Carcinoma 23950211 miR-153 supports colorectal cancer progression via pleiotropic effects that enhance invasion and chemotherapeutic resistance. other hsa-mir-106a Colorectal Carcinoma 23950216 Fecal miR-106a is a good molecular marker to identify colorectal cancer patients from among those with negative iFOBT results. FmiRT combined with iFOBT may improve the sensitivity to detect colorectal cancer. other hsa-mir-105 Neoplasms [unspecific] 23950948 miR-105 inhibits prostate tumour growth by suppressing CDK6 levels. other hsa-mir-185 Prostate Neoplasms 23951060 MicroRNA-185 and 342 inhibit tumorigenicity and induce apoptosis through blockade of the SREBP metabolic pathway in prostate cancer cells. other hsa-mir-342 Prostate Neoplasms 23951060 MicroRNA-185 and 342 inhibit tumorigenicity and induce apoptosis through blockade of the SREBP metabolic pathway in prostate cancer cells. other hsa-mir-136 "Carcinoma, Lung, Non-Small-Cell" 23959478 "miR-146a-5p circuitry uncouples cell proliferation and migration, but not differentiation, in human mesenchymal stem cells." other hsa-mir-214 "Carcinoma, Hepatocellular" 23962428 Downregulation of microRNA-214 and overexpression of FGFR-1 contribute to hepatocellular carcinoma metastasis. other hsa-mir-137 Huntington Disease 23965969 "Regulation of huntingtin gene expression by miRNA-137, -214, -148a, and their respective isomiRs." other hsa-mir-148a Huntington Disease 23965969 "Regulation of huntingtin gene expression by miRNA-137, -214, -148a, and their respective isomiRs." other hsa-mir-214 Huntington Disease 23965969 "Regulation of huntingtin gene expression by miRNA-137, -214, -148a, and their respective isomiRs." other hsa-mir-503 "Carcinoma, Hepatocellular" 23967867 "Our data highlight an important role for miR-503 in cell cycle regulation and in the molecular etiology of HCC, and implicate the potential application of miR-503 in prognosis prediction and miRNA-based HCC therapy." other hsa-mir-133a Colorectal Carcinoma 23968734 "miR-133a may play a key role in CRC genesis and metastasis, which suggests its potential role in the molecular therapy of cancer." other hsa-mir-222 Lung Neoplasms 23974492 Metformin inhibits lung cancer cells proliferation through repressing microRNA-222. other hsa-mir-17 "Lymphoma, Large-Cell, Anaplastic" 23975180 The microRNA-17~92 cluster is involved in lymphomagenesis of STAT3(+) ALCL and that its inhibition might represent an alternative avenue to interfere with ALK signaling in anaplastic large cell lymphomas. other hsa-mir-21 Renal Fibrosis 23978520 Microvesicle-mediated delivery of miR-21 among tubular epithelial cells might shed new light on the mechanism of progressive renal fibrosis. other hsa-mir-26b "Lymphoma, Non-Hodgkin" 23978716 Hepatitis C-associated B-cell non-Hodgkin lymphomas: the emerging role of miRNA-26b. other hsa-mir-433 Liver Neoplasms 23979134 MicroRNA-433 inhibits liver cancer cell migration by repressing the protein expression and function of cAMP response element-binding protein. other hsa-mir-338 Neurodegenerative Diseases [unspecific] 23979835 "The EnSCs can differentiate to oligodendrocyte cells by the overexpression of miR-338, and these cells can be used as a unique source for cell therapy of neurodegenerative disease." other hsa-mir-486 Lung Neoplasms 23980150 "Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer." other hsa-mir-21 Kidney Neoplasms 23981302 NF¦ÊB-mediated cyclin D1 expression by microRNA-21 influences renal cancer cell proliferation. other hsa-mir-23 Kaposi Sarcoma 23986579 Kaposi's sarcoma-associated herpesvirus encodes a mimic of cellular miR-23. other hsa-mir-34a "Carcinoma, Colon" 23991105 MicroRNA-34a mediates the autocrine signaling of PAR2-activating proteinase and its role in colonic cancer cell proliferation. other hsa-mir-16 Bladder Neoplasms 23991964 "miR-16 is an important regulator in bladder cancer, which will contribute to better understanding of important mis-regulated miRNAs." other hsa-mir-222 Breast Neoplasms 23994196 MiR-222 and miR-29a contribute to the drug-resistance of breast cancer cells. other hsa-mir-29a Breast Neoplasms 23994196 MiR-222 and miR-29a contribute to the drug-resistance of breast cancer cells. other hsa-mir-216a Acute Pancreatitis 23995054 MiR-216a and miR-216b as markers for acute phased pancreatic injury. other hsa-mir-216b Acute Pancreatitis 23995054 MiR-216a and miR-216b as markers for acute phased pancreatic injury. other hsa-mir-126 Colorectal Adenocarcinoma 23996930 Pomegranate polyphenolics suppressed azoxymethane-induced colorectal aberrant crypt foci and inflammation: possible role of miR-126/VCAM-1 and miR-126/PI3K/AKT/mTOR. other hsa-mir-21 "Carcinoma, Lung" 24004609 "Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cells." other hsa-mir-149 "Carcinoma, Lung, Non-Small-Cell" 24007627 A two miRNA signature (miR-149 and miR-375) was found predictive for response and was also associated to progression-free survival (p = 0.05). other hsa-mir-1288 Colorectal Carcinoma 24009195 Regulation of microRNA-1288 in colorectal cancer: altered expression and its clinicopathological significance. other hsa-mir-27a Ischemia-Reperfusion Injury 24009229 Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27. other hsa-mir-21 Lung Neoplasms 24012885 "Angiogenesis, mediated by miR-21, is involved arsenite-induced carcinogenesis." other hsa-mir-146a Autoimmune Diseases [unspecific] 24014244 Our data unravel the crucial immunomodulatory role of miR-146a in pDCs and may add to our understanding of aberrant responses in autoimmune diseases. other hsa-mir-7 Neoplasms [unspecific] 24014594 "we review the current knowledge about the ciRS-7/miR-7 axis in cancer-related pathways and discuss possible models explaining the relevance of coexpressing miR-7 along with a circRNA inhibitor. c-mir-221-3p,c-mir-223-3p" other hsa-mir-200 Neoplasms [unspecific] 24018975 The role of miR-200 in blocking cancer angiogenesis in a cancer-dependent context defines its utility as a potential therapeutic agent. other hsa-mir-34a Lung Neoplasms 24019906 the highly tumorigenic CD44(hi) cells are enriched for cells in the G2 phase of cell cycle. other hsa-mir-126 Atherosclerosis 24022569 "Increased miR-146a and miR-126 and reduced miR-155 levels were observed in both treatment groups (all, P<0.001)" other hsa-mir-204 Pancreatic Neoplasms 24025188 Triptolide mediated miR-204 increase causes pancreatic cancer cell death via loss of Mcl-1. other hsa-mir-145 "Adenocarcinoma, Lung" 24026105 miR-145 may have a cell type-specific function and play important roles in the process of BM from lung adenocarcinoma. other hsa-mir-222 Pancreatic Neoplasms 24026657 "This study provides the first evidence of a potential link between Ki67 and micro-RNA-222, which are both relevant to cell proliferation. Our data suggest the potential of micro-RNA-222 as a prognostic biomarker for the pancreatic cancer." other hsa-mir-130b Colorectal Carcinoma 24027433 MicroRNA-130b promotes tumor development and is associated with poor prognosis in colorectal cancer. other hsa-mir-30 Glomerulonephritis 24029422 Downregulation of microRNA-30 facilitates podocyte injury and is prevented by glucocorticoids. other hsa-mir-126 "Lymphoma, T-Cell, Cutaneous" 24033365 "Taken together, our findings suggest that both malignant and non-malignant T cells express miR-155 in situ in CTCL. Moreover, they indicate heterogeneity in miR-155 expression among malignant T cells." other hsa-mir-155 "Lymphoma, T-Cell, Cutaneous" 24033365 "Taken together, our findings suggest that both malignant and non-malignant T cells express miR-155 in situ in CTCL. Moreover, they indicate heterogeneity in miR-155 expression among malignant T cells." other hsa-mir-146 Inflammation 24035832 Our findings reveal a novel regulatory module of two miRNA-mediated negative feedback loops that allows for the fine-tuning of the dynamics of key mediators in inflammation. other hsa-mir-21 Inflammation 24035832 Our findings reveal a novel regulatory module of two miRNA-mediated negative feedback loops that allows for the fine-tuning of the dynamics of key mediators in inflammation. other hsa-mir-221 Melanoma 24035906 we report the production of circular microRNA sponges against miR-21 or miR-221 in cell lines using the self-splicing permuted intron-exon sequences derived from T4 bacteriophage gene td. other hsa-mir-146a Myasthenia Gravis 24036458 We conclude that abnormal expression/regulation of miR-146a may play an important role in the regulation of AchR specific B cells and contribute to the pathogenesis of MG. other hsa-mir-144 Muscle Diseases [unspecific] 24036467 Our results reveal that there are changes in expression of known and novel miRNAs with skeletal muscle aging and that CR may reverse some of these changes to a younger phenotype. other hsa-mir-15a Muscle Diseases [unspecific] 24036467 Our results reveal that there are changes in expression of known and novel miRNAs with skeletal muscle aging and that CR may reverse some of these changes to a younger phenotype. other hsa-mir-181b Muscle Diseases [unspecific] 24036467 Our results reveal that there are changes in expression of known and novel miRNAs with skeletal muscle aging and that CR may reverse some of these changes to a younger phenotype. other hsa-mir-18a Muscle Diseases [unspecific] 24036467 Our results reveal that there are changes in expression of known and novel miRNAs with skeletal muscle aging and that CR may reverse some of these changes to a younger phenotype. other hsa-mir-451 Muscle Diseases [unspecific] 24036467 Our results reveal that there are changes in expression of known and novel miRNAs with skeletal muscle aging and that CR may reverse some of these changes to a younger phenotype. other hsa-mir-200 Breast Neoplasms 24037528 MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways. other hsa-mir-103 Polycystic Ovarian Syndrome 24037889 The present results suggest that miRNAs that play an important role in metabolic and immune system processes are influenced by obesity and circulating androgen concentrations. other hsa-mir-155 Polycystic Ovarian Syndrome 24037889 The present results suggest that miRNAs that play an important role in metabolic and immune system processes are influenced by obesity and circulating androgen concentrations. other hsa-mir-21 Polycystic Ovarian Syndrome 24037889 The present results suggest that miRNAs that play an important role in metabolic and immune system processes are influenced by obesity and circulating androgen concentrations. other hsa-mir-27b Polycystic Ovarian Syndrome 24037889 The present results suggest that miRNAs that play an important role in metabolic and immune system processes are influenced by obesity and circulating androgen concentrations. other hsa-mir-495 "Carcinoma, Lung, Non-Small-Cell" 24038379 miR-495 enhances the sensitivity of non-small cell lung cancer cells to platinum by modulation of copper-transporting P-type adenosine triphosphatase A (ATP7A). other hsa-mir-151 Myocardial Infarction 24039836 Downregulation of miR-151-5p contributes to increased susceptibility to arrhythmogenesis during myocardial infarction with estrogen deprivation. other hsa-mir-21 "Squamous Cell Carcinoma, Esophageal" 24039846 "MiR-21 expression is mostly confined to the SCC stroma and its release from fibroblasts influences the migration and invasion capacity of SCC cells. Moreover, miR-21 may be an important factor in activating fibroblasts to CAFs. These findings provide new insights into the role of CAFs and the extracellular matrix in tumor microenvironment formation and in tumor cell maintenance, and suggest miR-21 may contribute to cellular crosstalk in the tumor microenvironment." other hsa-mir-31 "Squamous Cell Carcinoma, Esophageal" 24039884 Dissection of miRNA-miRNA interaction in esophageal squamous cell carcinoma. other hsa-mir-338 "Squamous Cell Carcinoma, Esophageal" 24039884 Dissection of miRNA-miRNA interaction in esophageal squamous cell carcinoma. other hsa-let-7a Pancreatic Neoplasms 24040120 DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer. other hsa-mir-145 Pancreatic Neoplasms 24040120 DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer. other hsa-mir-200 Pancreatic Neoplasms 24040120 DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer. other hsa-mir-21 Neoplasms [unspecific] 24041029 Here we summarize current knowledge on miR-21 functions in human cancers and discuss how this finding provides insight into the role of miR-21 as an oncogenic regulator in stem/progenitor cell populations of human cancers. other hsa-mir-125a Lung Neoplasms 24044511 MicroRNA hsa-miR-125a-3p activates p53 and induces apoptosis in lung cancer cells. other hsa-mir-122 "Leukemia, Lymphocytic, Chronic, B-Cell" 24047131 Four-way junction formation promoting ultrasensitive electrochemical detection of microRNA. other hsa-mir-100 Vulvar Squamous Cell Carcinoma 24048714 "In conclusion, our study demonstrates that microRNAs may be clinically important in vulvar carcinomas and our findings may help for further studies on functional implications of miRNA deregulation in this type of cancer." other hsa-mir-133a Vulvar Squamous Cell Carcinoma 24048714 "In conclusion, our study demonstrates that microRNAs may be clinically important in vulvar carcinomas and our findings may help for further studies on functional implications of miRNA deregulation in this type of cancer." other hsa-mir-19b-1 Vulvar Squamous Cell Carcinoma 24048714 "In conclusion, our study demonstrates that microRNAs may be clinically important in vulvar carcinomas and our findings may help for further studies on functional implications of miRNA deregulation in this type of cancer." other hsa-mir-223 Vulvar Squamous Cell Carcinoma 24048714 "In conclusion, our study demonstrates that microRNAs may be clinically important in vulvar carcinomas and our findings may help for further studies on functional implications of miRNA deregulation in this type of cancer." other hsa-mir-519b Vulvar Squamous Cell Carcinoma 24048714 "In conclusion, our study demonstrates that microRNAs may be clinically important in vulvar carcinomas and our findings may help for further studies on functional implications of miRNA deregulation in this type of cancer." other hsa-mir-29 Liver Injury 24052410 "Our results indicate that miR-29a decreases cholestatic liver injury and fibrosis after BDL, at least partially, by modulating the extrinsic rather than intrinsic pathway of apoptosis." other hsa-mir-1321 Pediatric Glioma 24053158 In the present study we identified the changed expression pattern of microRNAs in pediatric gliamas. Our study also provides a better understanding of pediatric brain tumor biology and may assist in the development of less toxic therapies and in the search for better markers for disease stratification. other hsa-mir-513b Pediatric Glioma 24053158 In the present study we identified the changed expression pattern of microRNAs in pediatric gliamas. Our study also provides a better understanding of pediatric brain tumor biology and may assist in the development of less toxic therapies and in the search for better markers for disease stratification. other hsa-mir-769 Pediatric Glioma 24053158 In the present study we identified the changed expression pattern of microRNAs in pediatric gliamas. Our study also provides a better understanding of pediatric brain tumor biology and may assist in the development of less toxic therapies and in the search for better markers for disease stratification. other hsa-mir-29 Crohn Disease 24054330 The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release. other hsa-mir-129 Gastric Neoplasms 24055727 Growth inhibitory effects of three miR-129 family members on gastric cancer. other hsa-mir-1246 "Carcinoma, Hepatocellular" 24060847 The manipulation of one or more of these miRNAs could be an important approach for the improved management of paclitaxel therapy. other hsa-mir-1260b "Carcinoma, Hepatocellular" 24060847 The manipulation of one or more of these miRNAs could be an important approach for the improved management of paclitaxel therapy. other hsa-mir-1274a "Carcinoma, Hepatocellular" 24060847 The manipulation of one or more of these miRNAs could be an important approach for the improved management of paclitaxel therapy. other hsa-mir-1290 "Carcinoma, Hepatocellular" 24060847 The manipulation of one or more of these miRNAs could be an important approach for the improved management of paclitaxel therapy. other hsa-mir-183 "Carcinoma, Hepatocellular" 24060847 The manipulation of one or more of these miRNAs could be an important approach for the improved management of paclitaxel therapy. other hsa-mir-21 "Carcinoma, Hepatocellular" 24060847 The manipulation of one or more of these miRNAs could be an important approach for the improved management of paclitaxel therapy. other hsa-mir-508 "Carcinoma, Hepatocellular" 24060847 The manipulation of one or more of these miRNAs could be an important approach for the improved management of paclitaxel therapy. other hsa-mir-877 "Carcinoma, Hepatocellular" 24060847 The manipulation of one or more of these miRNAs could be an important approach for the improved management of paclitaxel therapy. other hsa-mir-126 Allergy 24063594 "Expression kinetics of miRNA involved in dermal toluene 2,4-diisocyanate sensitization." other hsa-mir-155 Allergy 24063594 "Expression kinetics of miRNA involved in dermal toluene 2,4-diisocyanate sensitization." other hsa-mir-21 Allergy 24063594 "Expression kinetics of miRNA involved in dermal toluene 2,4-diisocyanate sensitization." other hsa-mir-210 Allergy 24063594 "Expression kinetics of miRNA involved in dermal toluene 2,4-diisocyanate sensitization." other hsa-mir-22 Allergy 24063594 "Expression kinetics of miRNA involved in dermal toluene 2,4-diisocyanate sensitization." other hsa-mir-27b Allergy 24063594 "Expression kinetics of miRNA involved in dermal toluene 2,4-diisocyanate sensitization." other hsa-mir-31 Allergy 24063594 "Expression kinetics of miRNA involved in dermal toluene 2,4-diisocyanate sensitization." other hsa-mir-1290 Celiac Disease 24063611 microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts. other hsa-mir-192 Celiac Disease 24063611 microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts. other hsa-mir-194 Celiac Disease 24063611 microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts. other hsa-mir-31 Celiac Disease 24063611 microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts. other hsa-mir-551a Celiac Disease 24063611 microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts. other hsa-mir-551b Celiac Disease 24063611 microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts. other hsa-mir-638 Celiac Disease 24063611 microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts. other hsa-mir-144 "Carcinoma, Lung, Non-Small-Cell" 24066116 "Our results for the first time showed mir-144-ZFX pathway is involved in the development of NSCLC, which sheds a light for further investigations on underlying mechanisms toward better understanding and management of NSCLC." other hsa-mir-199 Liver Neoplasms 24069256 "We exploited this miR-199 differential expression to develop a conditionally replication-competent oncolytic adenovirus, Ad-199T, and achieve tumor-specific viral expression and replication. " other hsa-mir-23b Pancreatic Adenocarcinoma 24070722 "Mir-23B might be used as a biomarker for PDAC resistance to radiotherapy or chemotherapy. Or, patients with low tumor levels of Mir-23B might benefit from pharmacologic inhibitors of autophagy." other hsa-let-7 Squamous Cell Carcinoma 24070899 "Phospho-¦¤Np63¦Á regulates AQP3, ALOX12B, CASP14 and CLDN1 expression through transcription and microRNA modulation." other hsa-mir-143 "Carcinoma, Endometrial" 24071015 Down-regulation of miR-145 and miR-143 might be associated with DNA methyltransferase 3B overexpression and worse prognosis in endometrioid carcinomas. other hsa-mir-145 "Carcinoma, Endometrial" 24071015 Down-regulation of miR-145 and miR-143 might be associated with DNA methyltransferase 3B overexpression and worse prognosis in endometrioid carcinomas. other hsa-mir-151 Hantavirus Infection 24074584 Our data suggest that differential immune responses following hantavirus infection may be regulated in part by cellular miRNA through dysregulation of genes critical to the inflammatory process. other hsa-mir-1973 Hantavirus Infection 24074584 Our data suggest that differential immune responses following hantavirus infection may be regulated in part by cellular miRNA through dysregulation of genes critical to the inflammatory process. other hsa-mir-182 "Carcinoma, Ovarian, Serous" 24077281 "We describe several mechanisms responsible for FOXO3a inactivity, including chromosomal deletion (chromosome 6q21), upregulation of miRNA-182 and destabilization by activated PI3K and MEK." other hsa-mir-182 Choriocarcinoma 24078156 " We have also shown the alterations in expressing profile of miR-31, miR-133a, miR-141, miR-145, miR-149, miR-182 and miR-194, which were observed even in the early stage of disease, and identified a set of genes, which take place in correct assigning of patients in dependence of CRC stage." other hsa-mir-194 Choriocarcinoma 24078156 " We have also shown the alterations in expressing profile of miR-31, miR-133a, miR-141, miR-145, miR-149, miR-182 and miR-194, which were observed even in the early stage of disease, and identified a set of genes, which take place in correct assigning of patients in dependence of CRC stage." other hsa-mir-31 Choriocarcinoma 24078156 " We have also shown the alterations in expressing profile of miR-31, miR-133a, miR-141, miR-145, miR-149, miR-182 and miR-194, which were observed even in the early stage of disease, and identified a set of genes, which take place in correct assigning of patients in dependence of CRC stage." other hsa-mir-34a Preeclampsia 24081307 "The results support a role for miR-34a in the pathophysiology of preeclampsia, through deregulation of the pri-miRNA expression and its altered maturation." other hsa-mir-29 Atrial Fibrillation 24085039 These new insights into mir29¡¯s functions further support a role for the adaptive immune system in the immunopathogenesis of AF. We recommend that AF investigators team up with immunologists in search for pathogenic T cells. other hsa-mir-33 Atherosclerosis 24086374 "These results reveal a novel mechanism for the BA-mediated ABCA1 expression, which may provide new insights for developing strategies for modulating vascular inflammation and atherosclerosis." other hsa-mir-200a Breast Neoplasms 24086551 "MiR-200b eRNA may be involved in the regulation of miR-200b~200a~429 gene expression and silencing. Taken together, these findings reveal the presence of a novel enhancer, which contributes to miR-200b~200a~429 transcriptional regulation in epithelial cells." other hsa-mir-200b Breast Neoplasms 24086551 "MiR-200b eRNA may be involved in the regulation of miR-200b~200a~429 gene expression and silencing. Taken together, these findings reveal the presence of a novel enhancer, which contributes to miR-200b~200a~429 transcriptional regulation in epithelial cells." other hsa-mir-429 Breast Neoplasms 24086551 "MiR-200b eRNA may be involved in the regulation of miR-200b~200a~429 gene expression and silencing. Taken together, these findings reveal the presence of a novel enhancer, which contributes to miR-200b~200a~429 transcriptional regulation in epithelial cells." other hsa-mir-150 "Leukemia, Acute" 24086639 "miR-150 promotes myeloid differentiation, a previously uncharacterized role for this miRNA, and that absent or low miR-150 expression contributes to blocked myeloid differentiation in acute leukemia cells." other hsa-mir-1227 Prostate Neoplasms 24091630 "Large oncosomes enhanced migration of cancer-associated fibroblasts (CAFs), an effect that was increased by miR-1227, a miRNA abundant in large oncosomes produced by RWPE-2 cells. " other hsa-mir-34a Malignant Neoplasms [unspecific] 24091633 miR-34a can potentially be exploited for DNA damage-effecting therapies of malignancies. other hsa-mir-29b Multiple Myeloma 24091729 miR-29b is endowed with epigenetic activity and mediates previously unknown functions of bortezomib in MM cells. other hsa-mir-210 Neoplasms [unspecific] 24098326 hypoxia related mir-210 and apoptosis-related mir-296-5p in the cancer mechanisms other hsa-mir-296 Neoplasms [unspecific] 24098326 hypoxia related mir-210 and apoptosis-related mir-296-5p in the cancer mechanisms other hsa-mir-125b Breast Neoplasms 24098452 "The expression of ENPEP and CK2-¦Á was inversely correlated with miR-125b expression in breast tumors,indicating the relevance of these potential oncogenic proteins in breast cancer patients. " other hsa-mir-210 Leishmaniasis 24098824 MicroRNA expression profile in human macrophages in response to Leishmania major infection. other hsa-mir-92b "Carcinoma, Lung, Non-Small-Cell" 24099768 "The miR-92b play an oncogene roles by regulatescell growth, cisplatin chemosensitivity phenotype, and could serve as a novel potential maker for NSCLC therapy." other hsa-mir-33a Liver Fibrosis 24100264 "the expression of miR-33a increased with the progression of liver fibrosis. These results suggested that anti-miR-33a inhibit activation and extracellular matrix production, at least in part, via the activation of PI3K/Akt pathway and PPAR-¦Á and anti sense of miR-33a may be a novel potential therapeutic approach for treating hepatic fibrosis in the future." other hsa-mir-29a Human Immunodeficiency Virus Infection 24103357 "The lack of significant negative correlation of miR-29a and TTP expression levels suggests that while miR-29a may contribute to TTP regulation, additional factors are involved. Reduced TTP expression during acute infection is consistent with increased cytokine production during this phase of infection, but the increases in TTP observed during late-stage infection were insufficient to halt runaway cytokine levels." other hsa-let-7a Breast Neoplasms 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-let-7b Breast Neoplasms 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-let-7c Breast Neoplasms 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-let-7d Breast Neoplasms 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-let-7f Breast Neoplasms 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-let-7g Breast Neoplasms 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-let-7i Breast Neoplasms 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-141 Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-15a Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-15b Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-16 Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-195 Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-200a Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-200b Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-200c Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-29a Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-29b Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-29c Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-30a Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-30b Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-30c Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-30d Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-30e Hereditary Breast Carcinoma 24104964 Our data demonstrate that BRCAX hereditary breast tumours can be sub-classified into four previously unknown homogenous groups characterised by specific miRNA expression signatures and histopathological features. other hsa-mir-143 Sepsis 24105952 "The toll-like receptor 3 ligand, poly(I:C), improves immunosuppressive function and therapeutic effect of mesenchymal stem cells on sepsis via inhibiting MiR-143." other hsa-mir-122 Hepatitis C Virus Infection 24106328 "By use of duplex and precursor miR-122 mimetic molecules that carried mutations in the passenger strand of miR-122, the effects on viral and reporter gene expression could be pinpointed to the action of precursor miR-122 molecules." other hsa-mir-29a "Scleroderma, Systemic" 24107002 Hair miR-29a levels are decreased in patients with scleroderma. other hsa-mir-196a-2 Colorectal Carcinoma 24107909 Meta-analysis of the association between a polymorphism in microRNA-196a2 and susceptibility to colorectal cancer. other hsa-mir-9 Viral Infectious Disease 24109243 Human coronavirus OC43 nucleocapsid protein binds microRNA 9 and potentiates NF-¦ÊB activation. other hsa-mir-21 "Carcinoma, Hepatocellular" 24112539 MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3. other hsa-mir-122 Liver Injury 24118944 M65 and microRNA-122 are potential biomarkers of DILI superior to ALT with respect to sensitivity and specificity. other hsa-mir-378 "Squamous Cell Carcinoma, Oral" 24120010 MicroRNA in oral squamous cell carcinoma other hsa-mir-122 Liver Diseases [unspecific] 24121065 miR-122 is a liver-specific microRNA associated with many liver diseases other hsa-mir-155 Neoplasms [unspecific] 24122356 microRNA-155 has functions in the control of various cancers other hsa-mir-101 Liver Neoplasms 24123132 Another myc in the wall: microRNA-101 controls important functions in liver cancer formation. other hsa-mir-483 "Carcinoma, Hepatocellular" 24127413 Exploration of genome-wide circulating microRNA in hepatocellular carcinoma:MiR-483-5p as a potential biomarker. other hsa-mir-122 "Carcinoma, Hepatocellular" 24130799 The continued expression of miR-122 in HCV-associated HCC may signify an important role for HCV replication late in the progression to malignancy. other hsa-mir-106b Prostate Neoplasms 24135225 Down-regulation of RE-1 silencing transcription factor (REST) in advanced prostate cancer by hypoxia-induced miR-106b~25. other hsa-mir-141 "Carcinoma, Hepatocellular" 24135722 Simultaneous silencing of miR-200c and miR-141 was likely to be responsible for the development of HCC-BDTT via ZEB1-directed EMT activation and Sec24a-mediated secretome. other hsa-mir-200 "Carcinoma, Hepatocellular" 24135722 Simultaneous silencing of miR-200c and miR-141 was likely to be responsible for the development of HCC-BDTT via ZEB1-directed EMT activation and Sec23a-mediated secretome. other hsa-mir-200c "Carcinoma, Hepatocellular" 24135722 Simultaneous silencing of miR-200c and miR-141 was likely to be responsible for the development of HCC-BDTT via ZEB1-directed EMT activation and Sec25a-mediated secretome. other hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 24136167 MicroRNA-155 controls RB phosphorylation in normal and malignant B lymphocytes via the noncanonical TGF-¦Â1/SMAD5 signaling module. other hsa-mir-320 "Adenocarcinoma, Gastric" 24136787 Strain-specific suppression of microRNA-320 by carcinogenic Helicobacter pylori promotes expression of the antiapoptotic protein Mcl-1. other hsa-mir-122 Hepatitis C Virus Infection 24141094 "The P body protein LSm1 contributes to stimulation of hepatitis C virus translation, but not replication, by microRNA-122." other hsa-let-7 Perlman Syndrome 24141620 Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs. other hsa-mir-196a-1 "Lymphoma, Hodgkin" 24145479 MicroRNA and gene networks in human Hodgkin's lymphoma. other hsa-mir-9 "Lymphoma, Hodgkin" 24145479 MicroRNA and gene networks in human Hodgkin's lymphoma. other hsa-mir-203 "Carcinoma, Esophageal" 24154605 Protamine sulfate-nanodiamond hybrid nanoparticles as a vector for MiR-203 restoration in esophageal carcinoma cells. other hsa-mir-127 Breast Neoplasms 24155205 MicroRNA-127 is downregulated by Tudor-SN protein and contributes to metastasis and proliferation in breast cancer cell line MDA-MB-231. other hsa-mir-133a Lung Neoplasms 24157646 A high-throughput screen identifies miRNA inhibitors regulating lung cancer cell survival and response to paclitaxel. other hsa-mir-133b Lung Neoplasms 24157646 A high-throughput screen identifies miRNA inhibitors regulating lung cancer cell survival and response to paclitaxel. other hsa-mir-346 Lung Neoplasms 24157646 A high-throughput screen identifies miRNA inhibitors regulating lung cancer cell survival and response to paclitaxel. other hsa-mir-361 Lung Neoplasms 24157646 A high-throughput screen identifies miRNA inhibitors regulating lung cancer cell survival and response to paclitaxel. other hsa-mir-361 "Carcinoma, Cervical" 24158756 MicroRNA-361-5p facilitates cervical cancer progression through mediation of epithelial-to-mesenchymal transition. other hsa-mir-139 Breast Neoplasms 24158791 miR-139-5p is a regulator of metastatic pathways in breast cancer. other hsa-mir-214 Renal Fibrosis 24158985 MicroRNA-214 antagonism protects against renal fibrosis. other hsa-mir-25 Heart Failure 24161931 Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure. other hsa-mir-106a Breast Neoplasms 24164962 Downregulation of miR-106b induced breast cancer cell invasion and motility in association with overexpression of matrix metalloproteinase 2. other hsa-mir-125b Breast Neoplasms 24165569 Taken together our results show a mechanism for EPO/EPOR and ERBB2 co-regulation in breast cancer and confirm the importance of miR-125b in controlling clinically-relevant cancer features. other hsa-mir-122 Obesity 24165878 Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells. other hsa-mir-33 Obesity 24165878 Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells. other hsa-mir-375 Neoplasms [unspecific] 24166096 The emerging role of miR-375 in cancer. other hsa-mir-154 Prostate Neoplasms 24166498 "MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b,miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells." other hsa-mir-299 Prostate Neoplasms 24166498 "MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b,miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells." other hsa-mir-376a Prostate Neoplasms 24166498 "MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b,miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells." other hsa-mir-376c Prostate Neoplasms 24166498 "MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b,miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells." other hsa-mir-377 Prostate Neoplasms 24166498 "MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b,miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells." other hsa-mir-381 Prostate Neoplasms 24166498 "MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b,miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells." other hsa-mir-485 Prostate Neoplasms 24166498 "MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b,miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells." other hsa-mir-487b Prostate Neoplasms 24166498 "MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b,miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells." other hsa-mir-654 Prostate Neoplasms 24166498 "MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b,miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells." other hsa-mir-200b Cholangiocarcinoma 24169343 Our study shows that miR-200b/c has a critical role in the regulation of the tumorigenic and metastatic capacity of cholangiocarcinoma and reveals the probable underlying mechanisms. other hsa-mir-200c Cholangiocarcinoma 24169343 Our study shows that miR-200b/c has a critical role in the regulation of the tumorigenic and metastatic capacity of cholangiocarcinoma and reveals the probable underlying mechanisms. other hsa-mir-27a Kidney Neoplasms 24173369 Combination of quercetin and hyperoside has anticancer effects on renal cancer cells through inhibition of oncogenic microRNA-27a. other hsa-mir-183 Endometriosis 24173391 Downregulation of miR-183 inhibits apoptosis and enhances the invasive potential of endometrial stromal cells in endometriosis. other hsa-mir-10b "Carcinoma, Nasopharyngeal" 24175854 miR-10b promotes migration and invasion in nasopharyngeal carcinoma cells. other hsa-mir-125b Chondrosarcoma 24178909 "mTORC 1 inhibitor PRP-1 caused significant upregulation of tumor suppressors, such as miR20a, miR125b, and miR192; and downregulation of onco miRNAs, miR509-3p, miR589, miR490-3p, miR 550 in human chondrosarcoma JJ012 cell line" other hsa-mir-192 Chondrosarcoma 24178909 "mTORC 1 inhibitor PRP-1 caused significant upregulation of tumor suppressors, such as miR20a, miR125b, and miR192; and downregulation of onco miRNAs, miR509-3p, miR589, miR490-3p, miR 550 in human chondrosarcoma JJ012 cell line" other hsa-mir-20a Chondrosarcoma 24178909 "mTORC 1 inhibitor PRP-1 caused significant upregulation of tumor suppressors, such as miR20a, miR125b, and miR192; and downregulation of onco miRNAs, miR509-3p, miR589, miR490-3p, miR 550 in human chondrosarcoma JJ012 cell line" other hsa-mir-490 Chondrosarcoma 24178909 "mTORC 1 inhibitor PRP-1 caused significant upregulation of tumor suppressors, such as miR20a, miR125b, and miR192; and downregulation of onco miRNAs, miR509-3p, miR589, miR490-3p, miR 550 in human chondrosarcoma JJ012 cell line" other hsa-mir-509 Chondrosarcoma 24178909 "mTORC 1 inhibitor PRP-1 caused significant upregulation of tumor suppressors, such as miR20a, miR125b, and miR192; and downregulation of onco miRNAs, miR509-3p, miR589, miR490-3p, miR 550 in human chondrosarcoma JJ012 cell line" other hsa-mir-550 Chondrosarcoma 24178909 "mTORC 1 inhibitor PRP-1 caused significant upregulation of tumor suppressors, such as miR20a, miR125b, and miR192; and downregulation of onco miRNAs, miR509-3p, miR589, miR490-3p, miR 550 in human chondrosarcoma JJ012 cell line" other hsa-mir-589 Chondrosarcoma 24178909 "mTORC 1 inhibitor PRP-1 caused significant upregulation of tumor suppressors, such as miR20a, miR125b, and miR192; and downregulation of onco miRNAs, miR509-3p, miR589, miR490-3p, miR 550 in human chondrosarcoma JJ012 cell line" other hsa-mir-184 "Carcinoma, Hepatocellular" 24183204 miR-184 functions as an oncogenic regulator in hepatocellular carcinoma (HCC). other hsa-mir-29b Multiple Myeloma 24189534 miR-29b: a new demethylator in multiple myeloma. other hsa-mir-206 "Carcinoma, Lung" 24189536 "miR-206 is capable of suppressing a known oncogene, it might be a true tumor suppressor gene and, as such, be deleted, modified, or directly repressed in human tumors." other hsa-mir-4423 Lung Neoplasms 24191054 A primate-specific microRNA enters the lung cancer landscape. other hsa-mir-19a Psoriasis 24192448 Our results indicated hair root miR-19a levels are effective as a disease marker. other hsa-mir-200 Prostate Neoplasms 24193225 Regulation of epithelial plasticity by miR-424 and miR-200 in a new prostate cancer metastasis model. other hsa-mir-424 Prostate Neoplasms 24193225 Regulation of epithelial plasticity by miR-424 and miR-200 in a new prostate cancer metastasis model. other hsa-mir-524 Glioma 24194606 Comprehensive analysis of the functional microRNA-mRNA regulatory network identifies miRNA signatures associated with glioma malignant progression. other hsa-mir-628 Glioma 24194606 Comprehensive analysis of the functional microRNA-mRNA regulatory network identifies miRNA signatures associated with glioma malignant progression. other hsa-mir-101 Alzheimer Disease 24194717 "we found microRNAs, including miR-20a, miR-17, miR-34a, miR-155, miR-18a, miR-22, miR-26a, miR-101, miR-106b, and miR-125b, that might regulate the expression of nodes in the sub-network." other hsa-mir-106b Alzheimer Disease 24194717 "we found microRNAs, including miR-20a, miR-17, miR-34a, miR-155, miR-18a, miR-22, miR-26a, miR-101, miR-106b, and miR-125b, that might regulate the expression of nodes in the sub-network." other hsa-mir-17 Alzheimer Disease 24194717 "we found microRNAs, including miR-20a, miR-17, miR-34a, miR-155, miR-18a, miR-22, miR-26a, miR-101, miR-106b, and miR-125b, that might regulate the expression of nodes in the sub-network." other hsa-mir-20a Alzheimer Disease 24194717 "we found microRNAs, including miR-20a, miR-17, miR-34a, miR-155, miR-18a, miR-22, miR-26a, miR-101, miR-106b, and miR-125b, that might regulate the expression of nodes in the sub-network." other hsa-mir-141 Prostate Neoplasms 24195675 Sensitive detection of microRNA in complex biological samples via enzymatic signal amplification using DNA polymerase coupled with nicking endonuclease. other hsa-mir-221 Breast Neoplasms 24197133 14-3-3¦Æ orchestrates mammary tumor onset and progression via miR-221-mediated cell proliferation. other hsa-mir-10b "Carcinoma, Lung, Non-Small-Cell" 24198203 "microRNA expression profiles associated with survival, disease progression, and response to gefitinib in completely resected non-small-cell lung cancer with EGFR mutation." other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 24198203 "microRNA expression profiles associated with survival, disease progression, and response to gefitinib in completely resected non-small-cell lung cancer with EGFR mutation." other hsa-mir-30 "Leukemia, Myeloid, Acute" 24199710 Adverse prognostic value of MYBL2 overexpression and association with microRNA-30 family in acute myeloid leukemia patients. other hsa-mir-17 "Carcinoma, Lung, Non-Small-Cell" 24200043 "This work will provide a framework for constructing miRNA-TF synergistic regulatory networks, function analysis in diseases, and identification of the main regulators and regulatory motifs, which will be useful for understanding the putative regulatory motifs involving miRNAs and TFs, and for predicting new targets for cancer studies." other hsa-mir-570 "Carcinoma, Lung, Non-Small-Cell" 24200043 "This work will provide a framework for constructing miRNA-TF synergistic regulatory networks, function analysis in diseases, and identification of the main regulators and regulatory motifs, which will be useful for understanding the putative regulatory motifs involving miRNAs and TFs, and for predicting new targets for cancer studies." other hsa-mir-590 "Carcinoma, Lung, Non-Small-Cell" 24200043 "This work will provide a framework for constructing miRNA-TF synergistic regulatory networks, function analysis in diseases, and identification of the main regulators and regulatory motifs, which will be useful for understanding the putative regulatory motifs involving miRNAs and TFs, and for predicting new targets for cancer studies." other hsa-mir-888 Prostate Neoplasms 24200968 miR-888 is an expressed prostatic secretions-derived microRNA that promotes prostate cell growth and migration. other hsa-mir-223 Acute Coronary Syndrome 24202700 Decreased circulating microRNA-223 level predicts high on-treatment platelet reactivity in patients with troponin-negative non-ST elevation acute coronary syndrome. other hsa-mir-130b Colorectal Carcinoma 24204200 MicroRNA-130b promotes tumor development and is associated with poor prognosis in colorectal cancer. other hsa-mir-496 Breast Neoplasms 24204564 Methylated DNA binding domain protein 2 (MBD2) coordinately silences gene expression through activation of the microRNA hsa-mir-496 promoter in breast cancer cell line. other hsa-mir-139 "Squamous Cell Carcinoma, Esophageal" 24204738 Tumor-suppressive function of miR-139-5p in esophageal squamous cell carcinoma. other hsa-mir-125b "Carcinoma, Adrenocortical" 24205079 "miR-125b, miRNA-200b, miR-122, miRNA-466b, miR-138,vmiRNA-214, miRNA-503 and miRNA27a were down-regulated in response to 17¦Á-E2 treatment." other hsa-mir-132 "Carcinoma, Adrenocortical" 24205079 "ACTH up-regulated the expression of miRNA-212, miRNA-182, miRNA-183, miRNA-132, and miRNA-96 and down-regulated the levels of miRNA-466b, miRNA-214, miRNA-503, and miRNA-27a." other hsa-mir-212 "Carcinoma, Adrenocortical" 24205079 "The levels of miR-212,miRNA-183, miRNA-182, miRNA-132, miRNA-370, miRNA-377, and miRNA-96 were up-regulated, whereas miR-125b, miRNA-200b, miR-122, miRNA-466b, miR-138, miRNA-214, miRNA-503 and miRNA27a were down-regulated in response to 17¦Á-E2 treatment." other hsa-mir-21 Glioblastoma 24205116 MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development. other hsa-mir-10b Head And Neck Neoplasms 24209638 The study of microRNA alterations in HNSCC is an essential step to the mechanistic understanding of tumor formation and could lead to the discovery of clinically relevant biomarkers. other hsa-mir-196a Head And Neck Neoplasms 24209638 The study of microRNA alterations in HNSCC is an essential step to the mechanistic understanding of tumor formation and could lead to the discovery of clinically relevant biomarkers. other hsa-mir-548a Influenza 24210102 Expression of non-structural-1A binding protein in lung epithelial cells is modulated by miRNA-548an on exposure to influenza A virus. other hsa-mir-26a Glioblastoma 24211747 MiR-26a enhances the radiosensitivity of glioblastoma multiforme cells through targeting of ataxia-telangiectasia mutated. other hsa-mir-27a Alzheimer Disease 24212398 Our pilot study highlights hsa-miR-27a-3p as a candidate biomarker for AD and provides the groundwork for further confirmation studies in larger cohorts and in other hospitals. other hsa-mir-17 Cardiovascular Diseases [unspecific] 24212931 "The miR-17/92 cluster: a comprehensive update on its genomics, genetics,functions and increasingly important and numerous roles in health and disease." other hsa-mir-18 Cardiovascular Diseases [unspecific] 24212931 "The miR-17/92 cluster: a comprehensive update on its genomics, genetics,functions and increasingly important and numerous roles in health and disease." other hsa-mir-19a Cardiovascular Diseases [unspecific] 24212931 "The miR-17/92 cluster: a comprehensive update on its genomics, genetics,functions and increasingly important and numerous roles in health and disease." other hsa-mir-19b-1 Cardiovascular Diseases [unspecific] 24212931 "The miR-17/92 cluster: a comprehensive update on its genomics, genetics,functions and increasingly important and numerous roles in health and disease." other hsa-mir-20a Cardiovascular Diseases [unspecific] 24212931 "The miR-17/92 cluster: a comprehensive update on its genomics, genetics,functions and increasingly important and numerous roles in health and disease." other hsa-mir-92-1 Cardiovascular Diseases [unspecific] 24212931 "The miR-17/92 cluster: a comprehensive update on its genomics, genetics,functions and increasingly important and numerous roles in health and disease." other hsa-mir-185 Depression Disorder 24213247 "The involvement of microRNAs in major depression, suicidal behavior, and related disorders: a focus on miR-185 and miR-491-3p." other hsa-mir-491 Depression Disorder 24213247 "The involvement of microRNAs in major depression, suicidal behavior, and related disorders: a focus on miR-185 and miR-491-3p." other hsa-mir-192 "Carcinoma, Colon" 24213572 MicroRNA-192 suppresses liver metastasis of colon cancer. other hsa-mir-21 Acute Kidney Failure 24214874 MicroRNA-21 in the pathogenesis of acute kidney injury. other hsa-mir-125a Leukemia 24216483 ASXL1-MT resulted in derepression of homeobox A9 (Hoxa9) and microRNA-125a (miR-125a) expression through inhibition of polycomb repressive complex 2¨Cmediated (PRC2-mediated) methylation of histone H3K27. other hsa-mir-320a Gastrointestinal Stromal Tumor 24217767 MiR-320a downregulation is associated with imatinib resistance in gastrointestinal stromal tumors. other hsa-mir-203 "Carcinoma, Esophageal" 24219349 miR-203 inhibits the proliferation and self-renewal of esophageal cancer stem-like cells by suppressing stem renewal factor Bmi-1. other hsa-mir-130 Neoplasms [unspecific] 24220575 Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif. other hsa-mir-17 Neoplasms [unspecific] 24220575 Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif. other hsa-mir-19 Neoplasms [unspecific] 24220575 Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif. other hsa-mir-210 Neoplasms [unspecific] 24220575 Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif. other hsa-mir-455 Neoplasms [unspecific] 24220575 Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif. other hsa-mir-93 Neoplasms [unspecific] 24220575 Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif. other hsa-mir-367 Ovarian Neoplasms 24220856 "Overexpression of miR-367 in the paclitaxel-sensitive cells [PA1; IC??, 1.69 nM, high miR-367 (2.997), low miR-30a-5p (-0.323)] further increased paclitaxel sensitivity, whereas miR-367 depletion decreased paclitaxel sensitivity." other hsa-mir-1 Prostate Neoplasms 24222130 "In 22Rv1 cells, all AR isoforms were co-regulated by the cytoprotective factor HSPB1 and the tumor suppressor miR-1. Notably, our data provide evidence that HSPB1 inhibition is able to target expression of long as well as of short AR isoforms." other hsa-mir-183 "Carcinoma, Hepatocellular" 24222732 Expression and significance of microRNA-183 in hepatocellular carcinoma. other hsa-mir-196b Gastric Neoplasms 24222951 Co-activation of miR-196b and HOXA10 characterized a poor-prognosis subgroup of patients with gastric cancer. Elucidation of the biologic function of miR-196b and HOXA10 is warranted. other hsa-mir-135b Multiple Myeloma 24223191 Upregulation of miR-135b is involved in the impaired osteogenic differentiation of mesenchymal stem cells derived from multiple myeloma patients. other hsa-mir-4723 Prostate Neoplasms 24223753 MicroRNA-4723 inhibits prostate cancer growth through inactivation of the Abelson family of nonreceptor protein tyrosine kinases. other hsa-mir-142 Neoplasms [unspecific] 24227773 Two specific miRNAs transferred efficiently between these cells--miR-142 and miR-223--and both were endogenously expressed in macrophages and not in HCCs. other hsa-mir-429 Colorectal Carcinoma 24237355 miR-429 identified by dynamic transcriptome analysis is a new candidate biomarker for colorectal cancer prognosis. other hsa-mir-4661 Inflammation 24238336 The bipolar role of miR-4661 in inflammation. other hsa-mir-103a "Carcinoma, Colon" 24239208 "Our six-miRNA-based classifier is a reliable prognostic and predictive tool for disease recurrence in patients with stage II colon cancer,and might be able to predict which patients benefit from adjuvant chemotherapy.It might facilitate patient counselling and individualise management of patients with this disease." other hsa-mir-106b "Carcinoma, Colon" 24239208 "Our six-miRNA-based classifier is a reliable prognostic and predictive tool for disease recurrence in patients with stage II colon cancer,and might be able to predict which patients benefit from adjuvant chemotherapy.It might facilitate patient counselling and individualise management of patients with this disease." other hsa-mir-143 "Carcinoma, Colon" 24239208 "Our six-miRNA-based classifier is a reliable prognostic and predictive tool for disease recurrence in patients with stage II colon cancer,and might be able to predict which patients benefit from adjuvant chemotherapy.It might facilitate patient counselling and individualise management of patients with this disease." other hsa-mir-20a "Carcinoma, Colon" 24239208 "Our six-miRNA-based classifier is a reliable prognostic and predictive tool for disease recurrence in patients with stage II colon cancer,and might be able to predict which patients benefit from adjuvant chemotherapy.It might facilitate patient counselling and individualise management of patients with this disease." other hsa-mir-21 "Carcinoma, Colon" 24239208 "Our six-miRNA-based classifier is a reliable prognostic and predictive tool for disease recurrence in patients with stage II colon cancer,and might be able to predict which patients benefit from adjuvant chemotherapy.It might facilitate patient counselling and individualise management of patients with this disease." other hsa-mir-215 "Carcinoma, Colon" 24239208 "Our six-miRNA-based classifier is a reliable prognostic and predictive tool for disease recurrence in patients with stage II colon cancer,and might be able to predict which patients benefit from adjuvant chemotherapy.It might facilitate patient counselling and individualise management of patients with this disease." other hsa-mir-30c Adenovirus Infection 24239602 Comparison of RNAi with CCN2-modulating microRNA (miR) vectors expressing miR-30c or miR-133b showed higher efficacy of RNAi. other hsa-mir-145 Pleural Mesothelioma 24240684 Protumorigenic effects of mir-145 loss in malignant pleural mesothelioma. other hsa-mir-155 "Carcinoma, Nasopharyngeal" 24241359 MiR-155 up-regulation by LMP1 DNA contributes to increased nasopharyngeal carcinoma cell proliferation and migration. other hsa-mir-141 "Adenocarcinoma, Pancreatic Ductal" 24242138 Prognostic significance of microRNA-141 expression and its tumor suppressor function in human pancreatic ductal adenocarcinoma. other hsa-mir-31 Colorectal Carcinoma 24242331 "Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway." other hsa-mir-663 Prostate Neoplasms 24243035 miR-663 induces castration-resistant prostate cancer transformation and predicts clinical recurrence. other hsa-mir-124 Stroke 24244499 "miR-689, miR-124, and miR-155 were the most strongly associated miRNAs predicted to mediate pro-inflammatory pathways and M1-like activation phenotype." other hsa-mir-155 Stroke 24244499 "miR-155, the most strongly up-regulated miRNA,regulates the signal transducer and activator of transcription 3 signaling pathway enabling the late phase response to M1-skewing stimulation. " other hsa-mir-21 Breast Neoplasms 24248894 MicroRNA-21 in breast cancer: diagnostic and prognostic potential. other hsa-mir-23a Colorectal Carcinoma 24249161 MicroRNA-23a antisense enhances 5-fluorouracil chemosensitivity through APAF-1/caspase-9 apoptotic pathway in colorectal cancer cells. other hsa-let-7e Breast Neoplasms 24257477 "Our data provide novel evidence of the mechanisms behind miRNA dysregulation in breast cancer. The study contributes to the understanding of how methylation and copy number alterations influence miRNA expression, emphasizing miRNA functionality through redundant encoding, and suggests novel miRNAs important in breast cancer." other hsa-mir-100 Neoplasms [unspecific] 24258109 Prognostic role of microRNA-100 in various carcinomas: evidence from six studies. other hsa-mir-148a Osteoarthritis 24269634 "Overexpression of hsa-miR-148a inhibits hypertrophic differentiation and increases the production and deposition of type II collagen by OA chondrocytes, which is accompanied by an increased retention of proteoglycans.Hsa-miR-148a might be a potential disease-modifying compound in OA, as it promotes hyaline cartilage production." other hsa-mir-23a Myocardial Infarction 24269648 MicroRNA-23a is involved in tumor necrosis factor-¦Á induced apoptosis in mesenchymal stem cells and myocardial infarction. other hsa-mir-204 Pulmonary Hypertension 24270264 "We also showed that PARP-1 activation accounts for miR-204 downregulation (quantitative reverse transcription polymerase chain reaction) and the subsequent activation of the transcription factors nuclear factor of activated T cells and hypoxia-inducible factor 1-α in PAH-PASMCs, previously shown to be critical for PAH in several models." other hsa-mir-9 "Leukemia, Myeloid, Acute" 24270738 miR-9 is a tumor suppressor in pediatric AML other hsa-mir-122 Chronic Hepatitis C 24270780 "Reply to miR-122, IL28B genotype and the response to interferon in chronic hepatitis C virus infection." other hsa-mir-122 Chronic Hepatitis C 24270782 "miR-122, IL28B genotype and the response to interferon in chronic hepatitis C virus infection." other hsa-mir-214 Glioma 24277415 Combined aberrant expression of microRNA-214 and UBC9 is an independent unfavorable prognostic factor for patients with gliomas. other hsa-mir-338 Colorectal Carcinoma 24277750 MicroRNA-338-3p could inhibit colorectal carcinoma cell invasion and migration by inhibiting smoothened expression. other hsa-mir-503 Chikungunya Virus Infection 24278205 Combined miRNA and mRNA signature identifies key molecular players and pathways involved in chikungunya virus infection in human cells. other hsa-mir-638 Chikungunya Virus Infection 24278205 Combined miRNA and mRNA signature identifies key molecular players and pathways involved in chikungunya virus infection in human cells. other hsa-mir-744 Chikungunya Virus Infection 24278205 Combined miRNA and mRNA signature identifies key molecular players and pathways involved in chikungunya virus infection in human cells. other hsa-mir-132 Epilepsy 24282394 "Targeting miR-34a, miR-132 and miR-184 has been reported to alter seizure-induced neuronal death, whereas targeting miR-134 was neuroprotective, reduced seizure severity during status epilepticus and reduced the later emergence of recurrent spontaneous seizures." other hsa-mir-184 Epilepsy 24282394 "Targeting miR-34a, miR-132 and miR-184 has been reported to alter seizure-induced neuronal death, whereas targeting miR-134 was neuroprotective, reduced seizure severity during status epilepticus and reduced the later emergence of recurrent spontaneous seizures." other hsa-mir-323 Alzheimer Disease 24283221 "MicroRNA-323-3p with clinical potential in rheumatoid arthritis, Alzheimer's disease and ectopic pregnancy." other hsa-mir-155 "Aortic Aneurysm, Abdominal" 24283299 microRNA profiling in patients with abdominal aortic aneurysms: the significance of miR-155. other hsa-mir-30b "Carcinoma, Lung, Non-Small-Cell" 24286402 Our study identified miR-30b and miR-30c as useful prognostic predictors in NSCLC patients who underwent first line treatment with TKIs. other hsa-mir-30c "Carcinoma, Lung, Non-Small-Cell" 24286402 Our study identified miR-30b and miR-30c as useful prognostic predictors in NSCLC patients who underwent first line treatment with TKIs. other hsa-mir-17 Breast Neoplasms 24287487 Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer. other hsa-mir-20a Breast Neoplasms 24287487 Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer. other hsa-mir-206 Dermatomyositis 24288551 Correlation between the frequency of Th17 cell and the expression of microRNA-206 in patients with dermatomyositis. other hsa-mir-206 Melanoma 24289491 MicroRNA-206 induces G1 arrest in melanoma by inhibition of CDK4 and Cyclin D. other hsa-mir-29 Breast Neoplasms 24289849 The inhibitory role of Mir-29 in growth of breast cancer cells. other hsa-mir-196a-2 "Leukemia, Lymphoblastic, Acute" 24291415 Hsa-miR-196a2 polymorphism increases the risk of acute lymphoblastic leukemia in Chinese children. other hsa-mir-146a Systemic Lupus Erythematosus 24292724 STAT1 and miR-146a may be upregulated during inflammation and via proinflammatory cytokines and chemokines in SLE. Prolonged upregulation of STAT1 and miR-146a appears to play an important role in anemia in SLE patients. other hsa-mir-125b Alzheimer Disease 24293102 "Regulation of neurotropic signaling by the inducible, NF-kB-sensitive miRNA-125b in Alzheimer's disease (AD) and in primary human neuronal-glial (HNG) cells." other hsa-let-7a Lung Neoplasms 24293999 Targeted delivery of let-7a microRNA encapsulated ephrin-A1 conjugated liposomal nanoparticles inhibit tumor growth in lung cancer. other hsa-mir-26a "Carcinoma, Hepatocellular" 24296580 Hepatocellular carcinoma: New insight into angiogenesis in hepatocellular carcinoma: involvement of microRNA-26a. other hsa-mir-205 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 24297308 MicroRNA-205 suppresses proliferation and promotes apoptosis in laryngeal squamous cell carcinoma. other hsa-let-7b "Carcinoma, Hepatocellular" 24297460 Bioinformatic analysis of the membrane cofactor protein CD46 and microRNA expression in hepatocellular carcinoma. other hsa-mir-17 "Carcinoma, Hepatocellular" 24297460 Bioinformatic analysis of the membrane cofactor protein CD46 and microRNA expression in hepatocellular carcinoma. other hsa-mir-483 Neoplasms [unspecific] 24298054 The IGF2 intronic miR-483 selectively enhances transcription from IGF2 fetal promoters and enhances tumorigenesis. other hsa-mir-218 Lung Fibrosis 24298938 Andrographolide antagonizes cigarette smoke extract-induced inflammatory response and oxidative stress in human alveolar epithelial A549 cells through induction of microRNA-218. other hsa-mir-146b Prostate Neoplasms 24301753 "After Gene Set Functional Similarity analysis, we obtained 20 abnormal PC-related candidate miRNAs, including hsa-miR-26a, hsa-miR-152, hsa-miR-19a, hsa-miR-30c, hsa-miR-19b, and hsa-miR-146b-5p, among others." other hsa-mir-30c Prostate Neoplasms 24301753 "After Gene Set Functional Similarity analysis, we obtained 20 abnormal PC-related candidate miRNAs, including hsa-miR-26a, hsa-miR-152, hsa-miR-19a, hsa-miR-30c, hsa-miR-19b, and hsa-miR-146b-5p, among others." other hsa-mir-381 Neoplasms [unspecific] 24303078 Changes in the expression of miR-381 and miR-495 are inversely associated with the expression of the MDR1 gene and development of multi-drug resistance. other hsa-mir-495 Neoplasms [unspecific] 24303078 Changes in the expression of miR-381 and miR-495 are inversely associated with the expression of the MDR1 gene and development of multi-drug resistance. other hsa-mir-18b Melanoma 24303553 Role of miR-18b/MDM2/p53 circuitry in melanoma progression. other hsa-mir-155 Immune System Disease [unspecific] 24303979 Role of miR-155 in the regulation of lymphocyte immune function and disease. other hsa-mir-96 Neurodegenerative Diseases [unspecific] 24304186 Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96. other hsa-mir-210 "Carcinoma, Lung, Non-Small-Cell" 24305009 "We show that miR-210 in stromal cells, and co-expressed in cancer cells and stromal cells mediates an independent prognostic impact. It is a candidate marker for prognostic stratification in NSCLC." other hsa-mir-328 Glioma 24305703 MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation. other hsa-mir-17 Pediatric Glioma 24305714 Our results suggest that microRNA profiling represents a tool to distinguishing pediatric from adult HGG and that miR-17-92 cluster sustains pHGG. other hsa-mir-18 Pediatric Glioma 24305714 Our results suggest that microRNA profiling represents a tool to distinguishing pediatric from adult HGG and that miR-17-92 cluster sustains pHGG. other hsa-mir-19a Pediatric Glioma 24305714 Our results suggest that microRNA profiling represents a tool to distinguishing pediatric from adult HGG and that miR-17-92 cluster sustains pHGG. other hsa-mir-19b-1 Pediatric Glioma 24305714 Our results suggest that microRNA profiling represents a tool to distinguishing pediatric from adult HGG and that miR-17-92 cluster sustains pHGG. other hsa-mir-20a Pediatric Glioma 24305714 Our results suggest that microRNA profiling represents a tool to distinguishing pediatric from adult HGG and that miR-17-92 cluster sustains pHGG. other hsa-mir-92-1 Pediatric Glioma 24305714 Our results suggest that microRNA profiling represents a tool to distinguishing pediatric from adult HGG and that miR-17-92 cluster sustains pHGG. other hsa-mir-141 Osteosarcoma 24307282 Tumor-suppressing effects of miR-141 in human osteosarcoma. other hsa-mir-1 Glioblastoma 24310399 Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. other hsa-mir-30e Gastrointestinal Neoplasms 24312366 Identification of miR-30e* regulation of Bmi1 expression mediated by tumor-associated macrophages in gastrointestinal cancer. other hsa-mir-149 Gastrointestinal Neoplasms 24312386 "The present meta-analysis indicates that miR-499 may be associated with the risk to colorectal cancer. MiR-149 may confer a marginally increased risk of susceptibility to gastrointestinal cancer, especially for Asians." other hsa-mir-499 Gastrointestinal Neoplasms 24312386 "The present meta-analysis indicates that miR-499 may be associated with the risk to colorectal cancer. MiR-149 may confer a marginally increased risk of susceptibility to gastrointestinal cancer, especially for Asians." other hsa-mir-153 Fetal Alcohol Spectrum Disorder 24313161 Dysregulation of microRNA expression and function contributes to the etiology of fetal alcohol spectrum disorders. other hsa-mir-21 Fetal Alcohol Spectrum Disorder 24313161 Dysregulation of microRNA expression and function contributes to the etiology of fetal alcohol spectrum disorders. other hsa-mir-335 Fetal Alcohol Spectrum Disorder 24313161 Dysregulation of microRNA expression and function contributes to the etiology of fetal alcohol spectrum disorders. other hsa-mir-9 Fetal Alcohol Spectrum Disorder 24313161 Dysregulation of microRNA expression and function contributes to the etiology of fetal alcohol spectrum disorders. other hsa-mir-34 Asthma 24313771 Subtypes of asthma defined by epithelial cell expression of messenger RNA and microRNA. other hsa-mir-449 Asthma 24313771 Subtypes of asthma defined by epithelial cell expression of messenger RNA and microRNA. other hsa-mir-146a "Carcinoma, Hepatocellular" 24314246 "Drug-resistant HCC cells have abnormal expressed miRNAs, which may be explored to further investigate the association of miRNA expressions with multidrugs resistance in HCC." other hsa-mir-146b "Carcinoma, Hepatocellular" 24314246 "Drug-resistant HCC cells have abnormal expressed miRNAs, which may be explored to further investigate the association of miRNA expressions with multidrugs resistance in HCC." other hsa-mir-15a "Carcinoma, Hepatocellular" 24314246 "Drug-resistant HCC cells have abnormal expressed miRNAs, which may be explored to further investigate the association of miRNA expressions with multidrugs resistance in HCC." other hsa-mir-16 "Carcinoma, Hepatocellular" 24314246 "Drug-resistant HCC cells have abnormal expressed miRNAs, which may be explored to further investigate the association of miRNA expressions with multidrugs resistance in HCC." other hsa-mir-181d "Carcinoma, Hepatocellular" 24314246 "Drug-resistant HCC cells have abnormal expressed miRNAs, which may be explored to further investigate the association of miRNA expressions with multidrugs resistance in HCC." other hsa-mir-194 "Carcinoma, Hepatocellular" 24314246 "Drug-resistant HCC cells have abnormal expressed miRNAs, which may be explored to further investigate the association of miRNA expressions with multidrugs resistance in HCC." other hsa-mir-27b "Carcinoma, Hepatocellular" 24314246 "Drug-resistant HCC cells have abnormal expressed miRNAs, which may be explored to further investigate the association of miRNA expressions with multidrugs resistance in HCC." other hsa-mir-30b "Carcinoma, Hepatocellular" 24314246 "Drug-resistant HCC cells have abnormal expressed miRNAs, which may be explored to further investigate the association of miRNA expressions with multidrugs resistance in HCC." other hsa-mir-205 Human Papilloma Virus Infection 24314651 miR-24 and miR-205 expression is dependent on HPV onco-protein expression in keratinocytes. other hsa-mir-24 Human Papilloma Virus Infection 24314651 miR-24 and miR-205 expression is dependent on HPV onco-protein expression in keratinocytes. other hsa-mir-122 Hepatitis B Virus Infection 24314655 microRNA expression in hepatitis B virus infected primary treeshrew hepatocytes and the independence of intracellular miR-122 level for de novo HBV infection in culture. other hsa-mir-221 Gastric Neoplasms 24317477 Relapse-associated microRNA in gastric cancer patients after S-1 adjuvant chemotherapy. other hsa-mir-422a Gastric Neoplasms 24317477 Relapse-associated microRNA in gastric cancer patients after S-1 adjuvant chemotherapy. other hsa-mir-4732 Gastric Neoplasms 24317477 Relapse-associated microRNA in gastric cancer patients after S-1 adjuvant chemotherapy. other hsa-mir-4758 Gastric Neoplasms 24317477 Relapse-associated microRNA in gastric cancer patients after S-1 adjuvant chemotherapy. other hsa-mir-92b Gastric Neoplasms 24317477 Relapse-associated microRNA in gastric cancer patients after S-1 adjuvant chemotherapy. other hsa-mir-127 "Adenocarcinoma, Lung" 24317514 Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma. other hsa-mir-376a "Adenocarcinoma, Lung" 24317514 Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma. other hsa-mir-26a Pulmonary Hypertension 24328779 miR-26a linked to pulmonary hypertension by global assessment of circulating extracellular microRNAs. other hsa-mir-193a "Carcinoma, Hepatocellular" 24330766 Effects of miR-193a and sorafenib on hepatocellular carcinoma cells. other hsa-mir-155 Encephalomyelitis 24332164 MicroRNA-155 modulates Th1 and Th17 cell differentiation and is associated with multiple sclerosis and experimental autoimmune encephalomyelitis. other hsa-mir-92a Pancreatic Neoplasms 24332650 miR-92a/DUSP10/JNK signalling axis promotes human pancreatic cancer cells proliferation. other hsa-mir-302 "Carcinoma, Endometrial" 24333727 MicroRNA miR-302 inhibits the tumorigenicity of endometrial cancer cells by suppression of Cyclin D1 and CDK1. other hsa-mir-29 Fuchs Endothelial Dystrophy 24334445 Decreased endothelial expression of miR-29 family members may be associated with increased subendothelial extracellular matrix accumulation in FECD. other hsa-mir-491 "Squamous Cell Carcinoma, Oral" 24335959 miRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis. other hsa-mir-148a Prostate Neoplasms 24337069 Comparative microRNA profiling of prostate carcinomas with increasing tumor stage by deep sequencing. other hsa-mir-200b Prostate Neoplasms 24337069 Comparative microRNA profiling of prostate carcinomas with increasing tumor stage by deep sequencing. other hsa-mir-20a Prostate Neoplasms 24337069 Comparative microRNA profiling of prostate carcinomas with increasing tumor stage by deep sequencing. other hsa-mir-375 Prostate Neoplasms 24337069 Comparative microRNA profiling of prostate carcinomas with increasing tumor stage by deep sequencing. other hsa-mir-7 "Carcinoma, Hepatocellular" 24339204 Downregulation of miR-7 upregulates Cullin 5 (CUL5) to facilitate G1/S transition in human hepatocellular carcinoma cells. other hsa-mir-608 "Adenocarcinoma, Lung" 24339958 Bcl-xL silencing induces alterations in hsa-miR-608 expression and subsequent cell death in A549 and SK-LU1 human lung adenocarcinoma cells. other hsa-mir-29 Bladder Outlet Obstruction 24340017 Mir-29 repression in bladder outlet obstruction contributes to matrix remodeling and altered stiffness. other hsa-mir-323b Hepatitis B Virus Infection 24341744 Association of a microRNA-323b polymorphism with the persistence of hepatitis B virus infection by the enhancement of viral replication. other hsa-mir-26a "Squamous Cell Carcinoma, Tongue" 24343426 "Expression, regulation and roles of miR-26a and MEG3 in tongue squamous cell carcinoma." other hsa-mir-155 Lymphoma 24345320 Primary vitreoretinal B-cell lymphoma and uveitis might be characterized by distinct microRNA signatures. Quantification of ocular microRNA-155 might be helpful in the differential diagnosis of these 2 diseases. other hsa-mir-30d Thyroid Neoplasms 24345332 Regulation of autophagy by miR-30d impacts sensitivity of anaplastic thyroid carcinoma to cisplatin. other hsa-mir-712 Atherosclerosis 24346612 The atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis. other hsa-mir-29 "Diabetes Mellitus, Type 2" 24349318 "Urinary miR-29a correlated with albuminuria while urinary miR-29b correlated with carotid intima-media thickness (cIMT) in patients with type 2 diabetes. Therefore, they may have the potential to serve as alternative biomarker for diabetic nephropathy and atherosclerosis in type 2 diabetes." other hsa-mir-19a "Leukemia, Myeloid, Acute" 24349422 HDAC inhibitors repress BARD1 isoform expression in acute myeloid leukemia cells via activation of miR-19a and/or b. other hsa-mir-19b "Leukemia, Myeloid, Acute" 24349422 HDAC inhibitors repress BARD1 isoform expression in acute myeloid leukemia cells via activation of miR-19a and/or b. other hsa-mir-126 Cardiovascular Diseases [unspecific] 24349482 miR-126 expression was depressed in the process of EPC EndMT. other hsa-mir-494 Diabetes Mellitus 24349514 "MicroRNA-494, upregulated by tumor necrosis factor-¦Á, desensitizes insulin effect in C2C12 muscle cells." other hsa-mir-217 Leukemia 24350829 "Downregulation of miR-217 correlates with resistance of Ph(+) leukemia cells to ABL tyrosine kinase inhibitors. miR-#-5p,miR-#-3p" other hsa-mir-200 Gastric Neoplasms 24352645 We have uncovered a key microRNA regulatory network that defines the mesenchymal gastric cancer subtype significantly associated with poor overall survival in gastric cancer other hsa-mir-185 Gastric Neoplasms 24352663 miR-185 is an independent prognosis factor and suppresses tumor metastasis in gastric cancer. other hsa-mir-148b Alzheimer Disease 24352679 Constructing and characterizing a bioactive small molecule and microRNA association network for Alzheimer's disease. other hsa-mir-15a Alzheimer Disease 24352679 Constructing and characterizing a bioactive small molecule and microRNA association network for Alzheimer's disease. other hsa-mir-122 Liver Diseases [unspecific] 24354366 Roadmap of miR-122-related clinical application from bench to bedside. other hsa-mir-106b "Carcinoma, Hepatocellular" 24358224 Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. other hsa-mir-17 "Carcinoma, Hepatocellular" 24358224 Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. other hsa-mir-18 "Carcinoma, Hepatocellular" 24358224 Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. other hsa-mir-191 "Carcinoma, Hepatocellular" 24358224 Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. other hsa-mir-19a "Carcinoma, Hepatocellular" 24358224 Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. other hsa-mir-19b-1 "Carcinoma, Hepatocellular" 24358224 Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. other hsa-mir-20a "Carcinoma, Hepatocellular" 24358224 Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. other hsa-mir-21 "Carcinoma, Hepatocellular" 24358224 Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. other hsa-mir-92-1 "Carcinoma, Hepatocellular" 24358224 Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. other hsa-mir-142 Systemic Mastocytosis 24361879 miR-142-3p enhances Fc¦ÅRI-mediated degranulation in mast cells. other hsa-mir-2909 Viral Infectious Disease 24361962 Arsenic programmes cellular genomic-immunity through miR-2909 RNomics. other hsa-mir-499 Myocardial Infarction 24363996 Treatment with cLA and nitrite significantly induced levels of miRNA-499 compared to untreated MI mice. other hsa-mir-126 Neoplasms [unspecific] 24368110 miR-126 in human cancers: clinical roles and current perspectives. other hsa-mir-144 "Carcinoma, Esophageal" 24369245 miRNA-144 in the saliva is a genetic marker for early diagnosis of esophageal cancer other hsa-mir-205 Prostate Neoplasms 24370341 miR-205 impairs the autophagic flux and enhances cisplatin cytotoxicity in castration-resistant prostate cancer cells. other hsa-mir-21 Diabetic Nephropathy 24370587 Tongxinluo ameliorates renal structure and function by regulating miR-21-induced epithelial-to-mesenchymal transition in diabetic nephropathy. other hsa-mir-193b "Squamous Cell Carcinoma, Skin or Unspecific" 24374827 miR-193b/365a cluster controls progression of epidermal squamous cell carcinoma. other hsa-mir-365a "Squamous Cell Carcinoma, Skin or Unspecific" 24374827 miR-193b/365a cluster controls progression of epidermal squamous cell carcinoma. other hsa-mir-497 Colorectal Carcinoma 24375248 MicroRNA-497 and bufalin act synergistically to inhibit colorectal cancer metastasis. other hsa-mir-200 Colorectal Carcinoma 24376848 The role of microRNA-200 in progression of human colorectal and breast cancer. other hsa-mir-126 "Carcinoma, Cervical" 24377569 miR-126 Suppresses the proliferation of cervical cancer cells and alters cell sensitivity to the chemotherapeutic drug bleomycin other hsa-mir-27b "Leukemia, Myeloid" 24378438 (6)-Gingerolinduced myeloid leukemia cell death is initiated by reactive oxygen species and activation of miR-27b expression. other hsa-mir-92a "Diabetes Mellitus, Type 2" 24379347 "The updated subnetwork predicted that miR-126/-193b/-92a control CCL2 production by several TFs, including v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (ETS1), MYC-associated factor X (MAX), and specificity protein 12 (SP1)." other hsa-mir-155 Hepatitis C Virus Infection 24383923 MicroRNA-155 controls Toll-like receptor 3- and hepatitis C virus-induced immune responses in the liver. other hsa-mir-130a Hepatitis C Virus Infection 24383925 MicroRNA-130a inhibits HCV replication by restoring the innate immune response. other hsa-mir-122 Liver Neoplasms 24386085 ADAR2-mediated editing of miR-214 and miR-122 precursor and antisense RNA transcripts in liver cancers. other hsa-mir-214 Liver Neoplasms 24386085 ADAR2-mediated editing of miR-214 and miR-122 precursor and antisense RNA transcripts in liver cancers. other hsa-mir-17 Cardiovascular Diseases [unspecific] 24386440 "These findings revealed the role of miRNAs in h-ERG trafficking, which may contribute to the cardiac electrical disturbances associated with oxidative stress." other hsa-mir-200 "Lymphoma, Large B-Cell, Diffuse" 24390222 Inhibition of ZEB1 by miR-200 characterizes Helicobacter pylori-positive gastric diffuse large B-cell lymphoma with a less aggressive behavior. other hsa-mir-206 Lung Neoplasms 24390363 Quantitative proteomics and protein network analysis of A549 lung cancer cells affected by miR-206. other hsa-mir-9-1 Methylmalonic Acidemia 24390963 A Primary Study on Down-Regulated miR-9-1 and Its Biological Significances in Methylmalonic Acidemia. other hsa-mir-21 Wound Inflammation 24391209 Engulfment of apoptotic cells by macrophages: a role of microRNA-21 in the resolution of wound inflammation. other hsa-mir-23b Skin Neoplasms 24391759 UVA and UVB irradiation differentially regulate microRNA expression in human primary keratinocytes. other hsa-mir-155 Human Immunodeficiency Virus Infection 24391808 Cocaine enhances HIV-1 infectivity in monocyte derived dendritic cells by suppressing microRNA-155. other hsa-mir-200b Prostate Neoplasms 24391862 "miR-200b inhibits prostate cancer EMT, growth and metastasis." other hsa-mir-1 Prostate Neoplasms 24391925 Coordinate microRNA-mediated regulation of protein complexes in prostate cancer. other hsa-mir-16 Prostate Neoplasms 24391925 Coordinate microRNA-mediated regulation of protein complexes in prostate cancer. other hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 24392455 Hsa-miR-15a and Hsa-miR-16-1 expression is not related to proliferation centers abundance and other prognostic factors in chronic lymphocytic leukemia. other hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 24392455 Hsa-miR-15a and Hsa-miR-16-1 expression is not related to proliferation centers abundance and other prognostic factors in chronic lymphocytic leukemia. other hsa-let-7 Ovarian Neoplasms 24393345 Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200. other hsa-mir-200 Ovarian Neoplasms 24393345 Ovarian cancer cell invasiveness is associated with discordant exosomal sequestration of Let-7 miRNA and miR-200. other hsa-mir-210 Breast Neoplasms 24395300 Emerging roles of miR-210 and other non-coding RNAs in the hypoxic response. other hsa-mir-210 Pancreatic Neoplasms 24395300 Emerging roles of miR-210 and other non-coding RNAs in the hypoxic response. other hsa-mir-15a Diabetic Vasculopathy 24397367 "Vitamin D manipulates miR-181c, miR-20b and miR-15a in human umbilical vein endothelial cells exposed to a diabetic-like environment." other hsa-mir-181c Diabetic Vasculopathy 24397367 "Vitamin D manipulates miR-181c, miR-20b and miR-15a in human umbilical vein endothelial cells exposed to a diabetic-like environment." other hsa-mir-20b Diabetic Vasculopathy 24397367 "Vitamin D manipulates miR-181c, miR-20b and miR-15a in human umbilical vein endothelial cells exposed to a diabetic-like environment." other hsa-mir-503 Lung Neoplasms 24398307 "MiR-503 was able to reverse the cisplatin resistance of A549/DDP.MiR-503 processed this kind of effect by inhibiting the drug efflux,downregulating the expression of drug-resistant related proteins and promoting cell apoptosis." other hsa-mir-17 Breast Neoplasms 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets. other hsa-mir-182 Breast Neoplasms 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets. other hsa-mir-19a Breast Neoplasms 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets. other hsa-mir-200b Breast Neoplasms 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets. other hsa-mir-22 Breast Neoplasms 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets. other hsa-mir-24 Breast Neoplasms 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets. other hsa-mir-25 Breast Neoplasms 24398324 Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets. other hsa-mir-602 "Carcinoma, Hepatocellular, HBV-Related" 24398562 Arctiin induces an UVB protective effect in human dermal fibroblast cells through microRNA expression changes. other hsa-mir-194 "Adenocarcinoma, Pancreatic Ductal" 24398877 Upregulation of miR-194 contributes to tumor growth and progression in pancreatic ductal adenocarcinoma. other hsa-mir-340 Pediatric Osteosarcoma 24398981 Combined microRNA-340 and ROCK1 mRNA profiling predicts tumor progression and prognosis in pediatric osteosarcoma. other hsa-mir-223 Breast Neoplasms 24400121 miR-223 is a coordinator of breast cancer progression as revealed by bioinformatics predictions. other hsa-let-7c "Carcinoma, Lung, Non-Small-Cell" 24400442 Modulation of let-7c altered the sensitivity of A549/DDP cells to DDP through regulating DDP-induced apopotis. other hsa-mir-451 Rheumatoid Arthritis 24401767 Comprehensive analysis of miRNA expression in T-cell subsets of rheumatoid arthritis patients reveals defined signatures of naive and memory Tregs. other hsa-mir-511 "Adenocarcinoma, Lung" 24402374 miR-511 induces the apoptosis of radioresistant lung adenocarcinoma cells by triggering BAX. other hsa-mir-125b "Carcinoma, Cervical" 24402874 MicroRNAs as biomarkers of cervical cancer development: a literature review on miR-125b and miR-34a. other hsa-mir-34a "Carcinoma, Cervical" 24402874 MicroRNAs as biomarkers of cervical cancer development: a literature review on miR-125b and miR-34a. other hsa-mir-30a "Carcinoma, Renal Cell, Clear-Cell" 24402943 miR-30c-2-3p and miR-30a-3p: new pieces of the jigsaw puzzle in HIF2¦Á regulation. other hsa-mir-30c-2 "Carcinoma, Renal Cell, Clear-Cell" 24402943 miR-30c-2-3p and miR-30a-3p: new pieces of the jigsaw puzzle in HIF2¦Á regulation. other hsa-mir-375 "Carcinoma, Lung, Non-Small-Cell" 24404590 Decreased circulating miR-375: a potential biomarker for patients with non-small-cell lung cancer. other hsa-mir-146a "Carcinoma, Cervical" 24406730 Increased exosomal microRNA-21 and microRNA-146a levels in the cervicovaginal lavage specimens of patients with cervical cancer. other hsa-mir-21 "Carcinoma, Cervical" 24406730 Increased exosomal microRNA-21 and microRNA-146a levels in the cervicovaginal lavage specimens of patients with cervical cancer. other hsa-mir-378a Colorectal Carcinoma 24412052 Clinical and biological significance of miR-378a-3p and miR-378a-5p in colorectal cancer. other hsa-mir-23a "Carcinoma, Hepatocellular" 24417970 Correlation between miR-23a and onset of hepatocellular carcinoma. other hsa-mir-16 Glioblastoma 24418124 MicroRNA-16 inhibits glioma cell growth and invasion through suppression of BCL2 and the nuclear factor-¦ÊB1/MMP9 signaling pathway. other hsa-mir-337 Gastric Neoplasms 24422944 "These findings indicate that hsa-miR-337-3p plays a role in the reduction of gastric cancer cell invasion capacity, and further studies on the mechanism of hsa-miR-337-3p in gastric cancer metastasis are warranted." other hsa-mir-107 Childhood Obesity 24423308 "Childhood obesity is associated with changes in immune cell frequency, inflammatory environment, and regulation of metabolic gene expression.These changes have been causally linked to the onset of metabolic disease in adulthood and suggest the future trajectory of obese children to the development of type 2 diabetes mellitus and premature cardiovascular disease." other hsa-mir-33 Childhood Obesity 24423308 "Childhood obesity is associated with changes in immune cell frequency, inflammatory environment, and regulation of metabolic gene expression.These changes have been causally linked to the onset of metabolic disease in adulthood and suggest the future trajectory of obese children to the development of type 2 diabetes mellitus and premature cardiovascular disease." other hsa-mir-20a Alzheimer Disease 24423585 "The results of microarray analysis showed that miR-329, miR-193b, miR-20a, miR-296, and miR-130b were all upregulated in H2O2-induced primary hippocampal neurons and different strains of senescence accelerated mice." other hsa-mir-29b Uterine Leiomyoma 24424054 Down-regulation of miR-29b is essential for pathogenesis of uterine leiomyoma. other hsa-mir-141 "Squamous Cell Carcinoma, Head and Neck" 24424572 Role of miR-200c/miR-141 in the regulation of epithelial-mesenchymal transition and migration in head and neck squamous cell carcinoma. other hsa-mir-200c "Squamous Cell Carcinoma, Head and Neck" 24424572 Role of miR-200c/miR-141 in the regulation of epithelial-mesenchymal transition and migration in head and neck squamous cell carcinoma. other hsa-mir-146a "Carcinoma, Nasopharyngeal" 24430575 Association of miR-146a gene polymorphism with risk of nasopharyngeal carcinoma in the central-southern Chinese population. other hsa-mir-93 Inflammation 24433094 Expression of microRNA-93 and Interleukin-8 during Pseudomonas aeruginosa-mediated induction of proinflammatory responses. other hsa-mir-215 Hepatitis B Virus Infection 24434140 Hepatitis B virus X protein mutant HBx¦¤127 promotes proliferation of hepatoma cells through up-regulating miR-215 targeting PTPRT. other hsa-mir-125b Human Immunodeficiency Virus Infection 24434277 Methamphetamine inhibits HIV-1 replication in CD4+ T cells by modulating anti-HIV-1 miRNA expression. other hsa-mir-150 Human Immunodeficiency Virus Infection 24434277 Methamphetamine inhibits HIV-1 replication in CD4+ T cells by modulating anti-HIV-1 miRNA expression. other hsa-mir-28 Human Immunodeficiency Virus Infection 24434277 Methamphetamine inhibits HIV-1 replication in CD4+ T cells by modulating anti-HIV-1 miRNA expression. other hsa-mir-21 Gastric Neoplasms 24434352 the effect of celastrol on apoptosis was due to miR-21 inhibiting the PI3K/Akt-dependent NF-¦ÊB pathway. other hsa-mir-205 Lung Neoplasms 24434435 We have demonstrated for the first time a new molecular pathway that connects TMPRSS4 and integrin ¦Á5 through miR-205 to regulate cancer cell invasion and metastasis. other hsa-mir-34a Cardiovascular Diseases [unspecific] 24438466 MicroRNA-34a: role in cancer and cardiovascular disease. other hsa-mir-34a Neoplasms [unspecific] 24438466 MicroRNA-34a: role in cancer and cardiovascular disease. other hsa-mir-342 Alzheimer Disease 24440716 miR-342-5p decreases ankyrin G levels in Alzheimer's disease transgenic mouse models. other hsa-mir-146a Meningitis 24442429 Induction of endotoxin tolerance by pathogenic Neisseria is correlated with the inflammatory potential of lipooligosaccharides and regulated by microRNA-146a. other hsa-mir-106a Pancreatic Neoplasms 24444603 Upregulated miR-106a plays an oncogenic role in pancreatic cancer. other hsa-mir-34a "Carcinoma, Lung, Non-Small-Cell" 24444609 Restoration of p53/miR-34a regulatory axis decreases survival advantage and ensures Bax-dependent apoptosis of non-small cell lung carcinoma cells. other hsa-mir-200 Ovarian Neoplasms 24447705 Sequence variation among members of the miR-200 microRNA family is correlated with variation in the ability to induce hallmarks of mesenchymal-epithelial transition in ovarian cancer cells. other hsa-mir-21 Cardiovascular Diseases [unspecific] 24447911 "Ang II induced miR-21 expression in primary mouse cardiac fibroblasts (CFs) via ERK-dependent AP-1 and STAT3 activation, and while a miR-21 inhibitor reversed Ang II-induced RECK suppression, a miR-21 mimic inhibited both RECK expression and Ang II-induced CF migration." other hsa-mir-30c Prostate Neoplasms 24452717 MicroRNA-30c serves as an independent biochemical recurrence predictor and potential tumor suppressor for prostate cancer. other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 24452750 Expression of microRNA-21 in non-small cell lung cancer tissue increases with disease progression and is likely caused by growth conditional changes during malignant transformation. other hsa-mir-147 Neoplasms [unspecific] 24454732 MicroRNA-147 induces a mesenchymal-to-epithelial transition (MET) and reverses EGFR inhibitor resistance. other hsa-let-7 Osteosarcoma 24457375 the involvement of let-7 family miRNA in regulation of the cell proliferation as well as epithelial-mesenchymal transition of OS. other hsa-mir-888 Prostate Neoplasms 24457835 miR-888 is an expressed prostatic secretions-derived microRNA that promotes prostate cell growth and migration. other hsa-mir-10b Breast Neoplasms 24457988 Critical role of miR-10b in transforming growth factor-¦Â1-induced epithelial-mesenchymal transition in breast cancer. other hsa-mir-520d "Carcinoma, Hepatocellular" 24458129 Hsa-miR-520d induces hepatoma cells to form normal liver tissues via a stemness-mediated process. other hsa-mir-150 Atrial Fibrillation 24462065 Relation of reduced expression of MiR-150 in platelets to atrial fibrillation in patients with chronic systolic heart failure. other hsa-mir-150 Heart Failure 24462065 Relation of reduced expression of MiR-150 in platelets to atrial fibrillation in patients with chronic systolic heart failure. other hsa-mir-133a Colorectal Carcinoma 24464560 "DSS-induced chronic inflammation downregulates miR-133a and miR-143/145, which is reportedly associated with human colorectal cancer and PI3K/Akt activation." other hsa-mir-300 Glioma 24464870 mir-300 promotes self-renewal and inhibits the differentiation of glioma stem-like cells. other hsa-mir-206 Heart Failure 24465270 Provide a complex overview of microRNA-206. other hsa-mir-137 Glioblastoma 24465609 Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells. other hsa-mir-26a Ovarian Neoplasms 24466274 MiR-26a promotes ovarian cancer proliferation and tumorigenesis. other hsa-mir-21 IgA Nephropathy 24468088 Inhibition of miRNA-21 prevents fibrogenic activation in podocytes and tubular cells in IgA nephropathy. other hsa-mir-1 Arrhythmia 24468403 Down-regulation of miR-1 could relieve arrhythmogenesis by the anti-miR-1 antisense oligonucleotides (AMO-1). other hsa-mir-200c Lung Neoplasms 24468793 "Recent studies suggest that epithelial-mesenchymal transition (EMT) is the most important contributor to cancer metastasis. Induction of this complex process requires endogenously produced microRNAs; specifically, downregulation of the miRNA-200c causes an induction of EMT." other hsa-mir-155 Cardiovascular Diseases [unspecific] 24475727 The role of miRNA-155 in cardiovascular diseases other hsa-mir-182 Uterine Leiomyoma 24476133 "We observed that administration of MK-2206, an allosteric AKT inhibitor, increased levels of reactive oxygen species, up-regulated the microRNA miR-182 and several senescence-associated genes (including p16, p53, p21, and β-galactosidase), and drove leiomyoma cells into stress-induced premature senescence (SIPS)." other hsa-mir-27a Pancreatic Neoplasms 24479798 Our findings demonstrated that genistein plays a tumor suppressor role in part through inhibition of miR-27a in pancreatic cancer cells. other hsa-mir-92a Lipid Metabolism Disorder 24481837 MiR-92a: at the heart of lipid-driven endothelial dysfunction. other hsa-mir-128 "Carcinoma, Breast, Triple Negative" 24485087 "This study provides evidence of posttranscriptional downregulation of Smurf2 in triple-negative breast cancers, and demonstrates that the loss of RB function is involved in microRNA-mediated interference with Smurf2 translation.The new link from RB inactivation to Smurf2 downregulation is likely to play a role in malignant phenotypes of triple-negative breast cancer cells." other hsa-mir-15a "Carcinoma, Breast, Triple Negative" 24485087 "This study provides evidence of posttranscriptional downregulation of Smurf2 in triple-negative breast cancers, and demonstrates that the loss of RB function is involved in microRNA-mediated interference with Smurf2 translation.The new link from RB inactivation to Smurf2 downregulation is likely to play a role in malignant phenotypes of triple-negative breast cancer cells." other hsa-mir-15b "Carcinoma, Breast, Triple Negative" 24485087 "This study provides evidence of posttranscriptional downregulation of Smurf2 in triple-negative breast cancers, and demonstrates that the loss of RB function is involved in microRNA-mediated interference with Smurf2 translation.The new link from RB inactivation to Smurf2 downregulation is likely to play a role in malignant phenotypes of triple-negative breast cancer cells." other hsa-mir-16 "Carcinoma, Breast, Triple Negative" 24485087 "This study provides evidence of posttranscriptional downregulation of Smurf2 in triple-negative breast cancers, and demonstrates that the loss of RB function is involved in microRNA-mediated interference with Smurf2 translation.The new link from RB inactivation to Smurf2 downregulation is likely to play a role in malignant phenotypes of triple-negative breast cancer cells." other hsa-mir-138 Cardiovascular Diseases [unspecific] 24486907 Induction of microRNA-138 by pro-inflammatory cytokines causes endothelial cell dysfunction. other hsa-mir-21 Breast Neoplasms 24488617 The difference in miR-21 expression levels between invasive and non-invasive breast cancers emphasizes its role in breast cancer invasion. other hsa-mir-1228 Neoplasms [unspecific] 24488924 Human miR-1228 as a stable endogenous control for the quantification of circulating microRNAs in cancer patients. other hsa-mir-146b Breast Neoplasms 24498150 Unraveling the hidden heterogeneities of breast cancer based on functional miRNA cluster. other hsa-mir-10b Neoplasms [unspecific] 24503738 Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitor. other hsa-mir-23b Glioma 24503899 A lentivirus-mediated miR-23b sponge diminishes the malignant phenotype of glioma cells in vitro and in vivo. other hsa-let-7 Lung Neoplasms 24505620 Mechanistic links between COPD and lung cancer: a role of microRNA let-7 other hsa-mir-423 Heart Failure 24506564 The difference in transcoronary gradients between HF outpatients and controls suggests that miR-423-5p has a cardiac origin. The positive correlation between miR-423-5p and BNP transcoronary gradients supports this hypothesis. other hsa-mir-21 Neoplasms [unspecific] 24507038 "Our results demonstrated that HIF-1α could significantly upregulate α-smooth muscle actin expression, and reduced the E-cadherin expression in HK-2 cells during I/R injury. Moreover, miR-21 expression had a positive correlation with HIF-1α in this process." other hsa-mir-145 Myelodysplastic Syndromes 24507813 "Other genes, as well as miR-145 and miR-146a, contribute to aberrant megakaryopoiesis and a selective advantage for the del(5q) clone." other hsa-mir-192 Kidney Diseases [unspecific] 24508230 miR-192 induces G2/M growth arrest in aristolochic acid nephropathy. other hsa-mir-429 Colorectal Carcinoma 24510588 "miR-200a, miR-200c, miR-141, and miR-429 expression levels may identify CRC patients, including those with stage II disease, who are most likely to benefit from adjuvant chemotherapy." other hsa-mir-17 Feingold Syndrome 24511118 MicroRNA-17~92 is required for nephrogenesis and renal function. other hsa-mir-18 Feingold Syndrome 24511118 MicroRNA-17~92 is required for nephrogenesis and renal function. other hsa-mir-19a Feingold Syndrome 24511118 MicroRNA-17~92 is required for nephrogenesis and renal function. other hsa-mir-19b-1 Feingold Syndrome 24511118 MicroRNA-17~92 is required for nephrogenesis and renal function. other hsa-mir-20a Feingold Syndrome 24511118 MicroRNA-17~92 is required for nephrogenesis and renal function. other hsa-mir-92-1 Feingold Syndrome 24511118 MicroRNA-17~92 is required for nephrogenesis and renal function. other hsa-mir-335 "Carcinoma, Ovarian" 24515774 Our results indicate that miR-335 relates to the prognosis of patients with EOC and is a promising predictor of EOC recurrence. other hsa-mir-155 Encephalitis 24516198 Critical role of microRNA-155 in herpes simplex encephalitis. miR-H2 other hsa-mir-200 Breast Neoplasms 24518294 ¦Â1 integrin inhibition elicits a prometastatic switch through the TGF¦Â-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer. other hsa-mir-92a Viral Infectious Disease 24518554 Reply to Shin and Bayry on An age-related decline of CD62L and vaccine response: a role of microRNA 92a. other hsa-mir-203 "Squamous Cell Carcinoma, Esophageal" 24519530 Research on the typical miRNA and target genes in squamous cell carcinoma and adenocarcinoma of esophagus cancer with DNA microarray. other hsa-mir-21 "Squamous Cell Carcinoma, Esophageal" 24519530 Research on the typical miRNA and target genes in squamous cell carcinoma and adenocarcinoma of esophagus cancer with DNA microarray. other hsa-mir-155 Atopic Dermatitis 24521175 The presented concept offers a new option for the prevention of atopic diseases by the addition of physiological amounts of miR-155-enriched exosomes to infant formula for mothers incapable of breastfeeding. other hsa-mir-200a Pancreatic Neoplasms 24521357 MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell. other hsa-mir-143 Osteosarcoma 24525123 Exosome-formed synthetic microRNA-143 is transferred to osteosarcoma cells and inhibits their migration. other hsa-mir-155 Coronary Artery Disease 24525789 "miR-155 expression is associated inversely with complicated proatherogenic metabolic risk factors, and the severity of coronary stenotic lesions calculated by Gensini scores." other hsa-mir-155 Lung Neoplasms 24528019 "As Hsa-miR-155 (miR-155) can be used as a diagnostic marker for non-small cell lung cancer (NSCLC), a smart molecular beacon of miR-155 was designed to image the expression of miR-155 in NSCLC cases." other hsa-mir-150 Skin Disease [unspecific] 24530178 "miR-150 levels were significantly decreased in sera of scleroderma patients, and were inversely correlated with the prevalence of pitting scars/ulcers and the incidence of anti-topoisomerase I antibody." other hsa-mir-140 "Carcinoma, Tounge" 24530397 Reciprocal effects between microRNA-140-5p and ADAM10 suppress migration and invasion of human tongue cancer cells. other hsa-mir-95 "Carcinoma, Hepatocellular" 24530415 Role of microRNA-95 in the anticancer activity of Brucein D in hepatocellular carcinoma. other hsa-mir-122 "Carcinoma, Hepatocellular" 24531873 Antitumor function of microRNA-122 against hepatocellular carcinoma. other hsa-mir-34 Neoplasms [unspecific] 24532687 "Taken together, our results elucidated the intricate cross-talk between p53 and miR-34 miRNAs and revealed an important tumor suppressor effect generated by this positive feedback loop." other hsa-mir-493 "Carcinoma, Colon" 24533778 MKK7 mediates miR-493-dependent suppression of liver metastasis of colon cancer cells. other hsa-mir-132 Epilepsy 24553459 "miRNA represents a potentially important mechanism controlling protein levels in epilepsy. As such, miRNAs might be targeted to prevent or disrupt epilepsy as well as serve as diagnostic biomarkers of epileptogenesis." other hsa-mir-146a Epilepsy 24553459 "miRNA represents a potentially important mechanism controlling protein levels in epilepsy. As such, miRNAs might be targeted to prevent or disrupt epilepsy as well as serve as diagnostic biomarkers of epileptogenesis." other hsa-mir-23a Epilepsy 24553459 "miRNA represents a potentially important mechanism controlling protein levels in epilepsy. As such, miRNAs might be targeted to prevent or disrupt epilepsy as well as serve as diagnostic biomarkers of epileptogenesis." other hsa-mir-34a Epilepsy 24553459 "miRNA represents a potentially important mechanism controlling protein levels in epilepsy. As such, miRNAs might be targeted to prevent or disrupt epilepsy as well as serve as diagnostic biomarkers of epileptogenesis." other hsa-mir-34b Pleural Mesothelioma 24553485 Preclinical evaluation of microRNA-34b/c delivery for malignant pleural mesothelioma. other hsa-mir-34c Pleural Mesothelioma 24553485 Preclinical evaluation of microRNA-34b/c delivery for malignant pleural mesothelioma. other hsa-mir-137 Schizophrenia 24556472 Transcriptional consequences of schizophrenia candidate miR-137 manipulation in human neural progenitor cells. other hsa-mir-548 Neoplasms [unspecific] 24556720 Identification of a tumor-suppressive human-specific microRNA within the FHIT tumor-suppressor gene. other hsa-mir-124 Diabetic Nephropathy 24556741 These results provide a novel idea that curcumin prevents against podocytic adhesive capacity damage under mechanical stress by inhibitting miR-124 other hsa-mir-146a Enterovirus Infection 24561744 Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon. other hsa-mir-21 Atherosclerosis 24562307 "In ox-LDL treated VECs, transfection with a miR-21 mimic significantly increased miR-21 expression and inhibited PTEN expression, and attenuated the protective effects of paeonol pretreatment, whereas transfection with an miR-21 inhibitor significantly decreased miR-21 expression and increased PTEN expression, thus enhanced the protective effects of paeonol pretreatment." other hsa-mir-137 Schizophrenia 24566148 miR-137: a new player in schizophrenia. other hsa-mir-7 Gastric Neoplasms 24573489 miR-7 inhibits the invasion and metastasis of gastric cancer cells by suppressing epidermal growth factor receptor expression. other hsa-mir-29 Neoplasms [unspecific] 24573597 Our review highlights the diverse relationship between miR-29 and cancer (particularly digestive system neoplasms). other hsa-mir-21 Kidney Diseases [unspecific] 24576069 This review was performed to sum up the role of miR-21 and its signaling pathways in renal diseases. other hsa-mir-146a Colorectal Carcinoma 24576899 A microRNA-operated switch of asymmetric-to-symmetric cancer stem cell divisions. other hsa-mir-101 "Lymphoma, Burkitt" 24577510 "Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101." other hsa-mir-143 "Lymphoma, Burkitt" 24577510 "Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101." other hsa-mir-145 "Lymphoma, Burkitt" 24577510 "Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101." other hsa-mir-146a Toxoplasma gondii Infection 24582962 miR-146a and miR-155 delineate a MicroRNA fingerprint associated with Toxoplasma persistence in the host brain. other hsa-mir-155 Toxoplasma gondii Infection 24582962 miR-146a and miR-155 delineate a MicroRNA fingerprint associated with Toxoplasma persistence in the host brain. other hsa-mir-17 Toxoplasma gondii Infection 24583285 "Taken together, we describe a novel STAT3-miR-17-92-Bim pathway, thus providing a mechanistic explanation for inhibition of apoptosis of host cells following Toxoplasma infection." other hsa-mir-34a Neoplasms [unspecific] 24583844 miR-34a/SIRT6 in squamous differentiation and cancer. other hsa-mir-183 Lung Neoplasms 24586048 TGF-¦Â-inducible microRNA-183 silences tumor-associated natural killer cells. other hsa-mir-376a Viral Infectious Disease 24586166 MicroRNA editing facilitates immune elimination of HCMV infected cells. other hsa-mir-210 Neoplasms [unspecific] 24586608 "This systematic review and meta-analysis suggests that miR-210 has a predictive effect on survival of patients with studied cancer types as indexed by disease-free survival, progression-free survival and relapse-free survival. While the predictive effect on overall survival, breast cancer overall survival, breast cancer disease-free survival, sarcoma overall survival and renal cancer overall survival was not statistically significant." other hsa-mir-190b "Carcinoma, Hepatocellular" 24586785 Increased expression of miR-190 may cause decreased IGF-1 in HCC development. Insulin resistance appears to be a part of the physiopathologic significance of decreased IGF-1 levels in HCC progression. This study provides a novel miRNA-mediated regulatory mechanism for controlling IGF-1 expression in HCC and elucidates the biological relevance of this interaction in HCC. other hsa-mir-34a Multiple Myeloma 24587182 In vivo activity of miR-34a mimics delivered by stable nucleic acid lipid particles (SNALPs) against multiple myeloma. other hsa-mir-145 "Carcinoma, Endometrial" 24589415 Linc-RoR is a ceRNA and acts as a miR-145 sponge to inhibit mediation of the differentiation of ETs by miR-145. These results suggest that linc-RoR has an important role during endometrial carcinogenesis. other hsa-mir-155 Hepatitis C Virus Infection 24591085 MicroRNA-155 and microRNA-196b: promising biomarkers in hepatitis C virus infection other hsa-mir-196b Hepatitis C Virus Infection 24591085 MicroRNA-155 and microRNA-196b: promising biomarkers in hepatitis C virus infection other hsa-mir-210 Breast Neoplasms 24591754 "Our studies suggested that microRNA-210 could predict the outcome of patients with varieties of tumors, especially in breast cancers." other hsa-mir-499 Neoplasms [unspecific] 24593893 These results suggest that miR-499 delivered by the present system has excellent potency to treat cancer via integrative anticancer actions. other hsa-mir-34a "Carcinoma, Lung, Non-Small-Cell" 24595209 The microRNA miR-34a inhibits non-small cell lung cancer (NSCLC) growth and the CD44hi stem-like NSCLC cells. other hsa-mir-10 "Leukemia, Myeloid, Acute" 24596420 Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML. other hsa-mir-210 Chronic Hepatitis B 24597695 Studying the association of microRNA-210 level with chronic hepatitis B progression. other hsa-mir-107 Kidney Diseases [unspecific] 24597825 This review was performed to sum up the role of miR-107 and its signaling pathways in renal diseases. other hsa-mir-126 Multiple Sclerosis 24598267 "Our findings provided deeper insight into the mode of action of natalizumab, with possible implications for understanding both the effects of natalizumab on MS activity and its specific adverse event profile." other hsa-mir-155 Sepsis 24598292 "The result of this study suggest that miR-155 is involved in the cell proliferation regulation of CD4(+)CD25(+) Treg cells, and play some role in the immunological dissonance in sepsis." other hsa-mir-17 Neoplasms [unspecific] 24598644 Effect of microRNA-17-92 cluster on the biological characteristics of K562 cells and its mechanisms. other hsa-mir-200 Viral Infectious Disease 24599990 Host microRNA regulation of human cytomegalovirus immediate early protein translation promotes viral latency. other hsa-mir-16 Pancreatic Neoplasms 24600978 The combination of miR-16 and CA19-9 detections boosted the diagnostic performance in pancreatic cancer detection. other hsa-mir-7 Glioblastoma 24603851 miR-7 inhibits glioblastoma growth by simultaneously interfering with the PI3K/ATK and Raf/MEK/ERK pathways. other hsa-mir-155 Neuroinflammation 24604078 MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation. other hsa-mir-208 Pancreatic Neoplasms 24604208 miR-208-induced epithelial to mesenchymal transition of pancreatic cancer cells promotes cell metastasis and invasion. other hsa-mir-494 Gastric Neoplasms 24606447 Cinobufacin suppresses cell proliferation via miR-494 in BGC- 823 gastric cancer cells. other hsa-mir-21 Retinoblastoma 24607444 Seed-targeting anti-miR-21 inhibiting malignant progression of retinoblastoma and analysis of their phosphorylation signaling pathways. other hsa-mir-146a Inflammation 24607549 "In conclusion several aging-related mitomiRs may play a direct role in controlling mitochondrial function by regulating mitochondrial protein expression. Their modulation could thus mediate the loss of mitochondrial integrity and function in aging cells, inducing or contributing to the inflammatory response and to age-related diseases." other hsa-mir-34a Inflammation 24607549 "In conclusion several aging-related mitomiRs may play a direct role in controlling mitochondrial function by regulating mitochondrial protein expression. Their modulation could thus mediate the loss of mitochondrial integrity and function in aging cells, inducing or contributing to the inflammatory response and to age-related diseases." other hsa-mir-199a Kidney Neoplasms 24609899 miR-199a-3p inhibits hepatocyte growth factor/c-Met signaling in renal cancer carcinoma. other hsa-mir-133b Prostate Neoplasms 24610824 "miR-133b might enhance tumor-promoting properties in less aggressive LNCaP cells, whereas this miR may act as a tumor suppressor in more aggressive PC-3 cells. miR-133b and RB1CC1 were independent prognostic indicators for prostate cancer." other hsa-mir-214 Gastric Neoplasms 24614175 Clinicopathological significance of microRNA-214 in gastric cancer and its effect on cell biological behaviour. other hsa-mir-27b "Carcinoma, Hepatocellular" 24614526 Fumonisin B modulates expression of human cytochrome P450 1b1 in human hepatoma (Hepg2) cells by repressing Mir-27b. other hsa-mir-182 Colorectal Adenocarcinoma 24615484 The increased levels of the oncogene-like miR-182 increase the risk for disease progression and predict poor overall survival for colorectal adenocarcinoma patients. other hsa-mir-214 Colorectal Carcinoma 24616020 Identification of microRNA-214 as a negative regulator of colorectal cancer liver metastasis by way of regulation of fibroblast growth factor receptor 1 expression. other hsa-mir-648 Prostate Neoplasms 24618011 Our analysis revealed the scale-free features of the human miRNA-mRNA interaction network and showed the distinctive topological features of existing cancer miRNA biomarkers from previously published studies. A novel cancer miRNA biomarker prediction framework was designed based on these observations and applied to prostate cancer study. This method could be applied for miRNA biomarker prediction in other cancers. other hsa-mir-150 "Lymphoma, T-Cell, Cutaneous" 24627548 "In this issue of Blood, Ito et al demonstrate pathogenic implications of microRNA-150 (miR-150) repression in an aggressive form of cutaneous T-cell lymphoma (CTCL)." other hsa-mir-424 Psoriatic Arthritis 24628460 miR-424 levels in hair shaft are increased in psoriatic patients. other hsa-mir-15a "Leukemia, Myeloid, Chronic" 24629639 "We found that dasatinib (DAS) modulated miR-let-7d, miR-let-7e, miR-15a, miR-16, miR-21, miR-130a and miR-142-3p expressions while IM modulated miR-15a and miR-130a levels. miR-16, miR-130a and miR-145 expressions were modulated by nilotinib (NIL)." other hsa-mir-145 "Carcinoma, Hepatocellular" 24630966 MicroRNA-145: a promising biomarker for hepatocellular carcinoma (HCC). other hsa-mir-210 Colorectal Carcinoma 24632577 Hypoxia-inducible MiR-210 is an independent prognostic factor and contributes to metastasis in colorectal cancer. other hsa-mir-148b Colorectal Carcinoma 24632606 Altered p53 regulation of miR-148b and p55PIK contributes to tumor progression in colorectal cancer. other hsa-mir-18a "Carcinoma, Breast" 24633304 Our findings identify a mechanically regulated microRNA circuit that can promote malignancy and suggest potential prognostic roles for HOXA9 and miR-18a levels in stratifying patients with luminal breast cancers. other hsa-mir-150 Lymphoma 24633319 The previously reported up-regulation of miR-150 in marginal zone lymphoma of MALT type was verified in an independent cohort of lymphoma samples employing a modified methodology. This further substantiates the role of miR-150 as a potential oncomiR in MALT lymphoma. other hsa-mir-150 Early-Stage Small-Cell Lung Carcinoma 24637927 A microRNA signature predicts survival in early stage small-cell lung cancer treated with surgery and adjuvant chemotherapy. other hsa-mir-886 Early-Stage Small-Cell Lung Carcinoma 24637927 A microRNA signature predicts survival in early stage small-cell lung cancer treated with surgery and adjuvant chemotherapy. other hsa-mir-29 Crohn Disease 24641356 In Crohn's disease fibrosis-reduced expression of the miR-29 family enhances collagen expression in intestinal fibroblasts. other hsa-mir-144 Cardiovascular Diseases [unspecific] 24642088 7-Ketocholesterol inhibits isocitrate dehydrogenase 2 expression and impairs endothelial function via microRNA-144. other hsa-let-7a Ovarian Neoplasms 24643702 "E(2) + P4 significantly inhibited the cell survival, promoted the cell apoptosis, induced the expression of let-7a and miR-34b, and reduced the expression of Bcl-2 in ovarian cancer cells." other hsa-mir-34b Ovarian Neoplasms 24643702 "E(2) + P4 significantly inhibited the cell survival, promoted the cell apoptosis, induced the expression of let-7a and miR-34b, and reduced the expression of Bcl-2 in ovarian cancer cells." other hsa-mir-106 Gastric Neoplasms 24643999 "Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: results from the EPIC-EURGAST study." other hsa-mir-25 Gastric Neoplasms 24643999 "Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: results from the EPIC-EURGAST study." other hsa-mir-29 Gastric Neoplasms 24643999 "Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: results from the EPIC-EURGAST study." other hsa-mir-93 Gastric Neoplasms 24643999 "Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: results from the EPIC-EURGAST study." other hsa-mir-200c Prostate Neoplasms 24646496 Words of wisdom: Re: TMPRSS2-ERG gene fusions induce prostate tumorigenesis by modulating microRNA miR-200c. other hsa-mir-141 "Carcinoma, Renal Cell" 24647573 miR-141 serves as a potential biomarker for discriminating ccRCC from normal tissues and a crucial suppressor of ccRCC cell proliferation and metastasis by modulating the EphA2/p-FAK/p-AKT/MMPs signaling cascade. other hsa-mir-200c Liver Neoplasms 24647918 Synergistic antitumor activity of resveratrol and miR-200c in human lung cancer. other hsa-mir-452 Breast Neoplasms 24648265 MicroRNA-452 contributes to the docetaxel resistance of breast cancer cells. other hsa-let-7a "Lymphoma, Non-Hodgkin" 24648290 "Accordingly, c-Myc-targeting microRNAs let-7a and miR-26a were induced in all treated lymphomas and the cap-dependent translation machinery components 4E-BP1, eIF4E and eIF4G, as well as their upstream regulators, Akt and PIM kinases, were inhibited in function of the cell sensitivity to ITF2357, and, in turn, c-Myc downregulation." other hsa-mir-26a "Lymphoma, Non-Hodgkin" 24648290 "Accordingly, c-Myc-targeting microRNAs let-7a and miR-26a were induced in all treated lymphomas and the cap-dependent translation machinery components 4E-BP1, eIF4E and eIF4G, as well as their upstream regulators, Akt and PIM kinases, were inhibited in function of the cell sensitivity to ITF2357, and, in turn, c-Myc downregulation." other hsa-mir-378a Neoplasms [unspecific] 24651706 A screen identifies the oncogenic micro-RNA miR-378a-5p as a negative regulator of oncogene-induced senescence. other hsa-mir-223 Cardiovascular Diseases [unspecific] 24657505 miR-223 is one of the growing number of RNA biomarkers of various human metabolic diseases and is thus of special interest to both researchers and clinicians in the cardiovascular field. other hsa-mir-132 Toxoplasma gondii Infection 24657774 MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway. other hsa-mir-145 Neoplasms [unspecific] 24657914 miR-145 and its influence on tumor growth in systemic malignancies. other hsa-mir-17 Breast Neoplasms 24658544 miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1. other hsa-mir-20 Breast Neoplasms 24658544 miR-17/20 sensitization of breast cancer cells to chemotherapy-induced apoptosis requires Akt1. other hsa-let-7i Breast Neoplasms 24662829 "In breast cancer patients, significantly decreased let-7i levels were associated with missense mutations in p53." other hsa-mir-122 Chronic Hepatitis C 24672032 Reduction of microRNA 122 expression in IFNL3 CT/TT carriers and during progression of fibrosis in patients with chronic hepatitis C. other hsa-mir-221 Gastrointestinal Stromal Tumor 24674454 Multiple sporadic gastrointestinal stromal tumors concomitant with ampullary adenocarcinoma: a case report with KIT and PDGFRA mutational analysis and miR-221/222 expression profile. other hsa-mir-222 Gastrointestinal Stromal Tumor 24674454 Multiple sporadic gastrointestinal stromal tumors concomitant with ampullary adenocarcinoma: a case report with KIT and PDGFRA mutational analysis and miR-221/222 expression profile. other hsa-mir-940 Neoplasms [unspecific] 24675421 Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition. other hsa-mir-21 Ischemia-Reperfusion Injury 24676391 microRNA-21 protects against ischemia-reperfusion and hypoxia-reperfusion-induced cardiocyte apoptosis via the phosphatase and tensin homolog/Akt-dependent mechanism. other hsa-mir-21 "Squamous Cell Carcinoma, Oral" 24676554 STAT3 inhibitor WP1066 attenuates miRNA-21 to suppress human oral squamous cell carcinoma growth in vitro and in vivo. other hsa-mir-24 Hyperlipidemia 24677249 Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia. other hsa-mir-130a Fatty Liver [unspecific] 24677715 A novel function of microRNA 130a-3p in hepatic insulin sensitivity and liver steatosis. other hsa-mir-203 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 24682952 MiR-203 is downregulated in laryngeal squamous cell carcinoma and can suppress proliferation and induce apoptosis of tumours. other hsa-mir-155 Neoplasms [unspecific] 24687397 "In HepG2 cells, exogenous NO increases miR-155 expression, but endogenous basal NO inhibits it. Both effects are mediated via cGMP/PKG signaling. The upregulation of miR-155 by NO provides a new link between NO, inflammation, and cancer." other hsa-mir-122 "Carcinoma, Hepatocellular, HCV-Related" 24690114 Regulation of gene expression by microRNA in HCV infection and HCV-mediated hepatocellular carcinoma. other hsa-mir-194 "Adenocarcinoma, Colon" 24691499 miR-194 as a predictor for adenoma recurrence in patients with advanced colorectal adenoma after polypectomy. other hsa-mir-138 Lung Neoplasms 24691972 Up-regulation of microRNA-138 induce radiosensitization in lung cancer cells. other hsa-mir-203 "Squamous Cell Carcinoma, Esophageal" 24692008 MicroRNA-203 inhibits the progression of esophageal squamous cell carcinoma with restored epithelial tissue architecture in vivo. other hsa-mir-101 "Carcinoma, Hepatocellular, HBV-Related" 24697700 Functional analysis of miR-101-3p and Rap1b involved in hepatitis B virus-related hepatocellular carcinoma pathogenesis. other hsa-let-7 Neoplasms [unspecific] 24703842 We conclude that IMP3 RNPs may function as cytoplasmic safe houses and prevent miRNA-directed mRNA decay of oncogenes during tumor progression. other hsa-mir-612 Liver Neoplasms 24704424 MiR-612 suppresses the stemness of liver cancer via Wnt/¦Â-catenin signaling. other hsa-mir-302 Neoplasms [unspecific] 24705778 "In conclusion, the controversial role of miR-302-367 in different cell types may provide better understanding for its role in stemness level and its antitumorigenicity potential in different contexts." other hsa-mir-218 Gastrointestinal Stromal Tumor 24706111 microRNA-218 increase the sensitivity of gastrointestinal stromal tumor to imatinib through PI3K/AKT pathway. other hsa-mir-7 Breast Neoplasms 24707474 Trichostatin A suppresses EGFR expression through induction of microRNA-7 in an HDAC-independent manner in lapatinib-treated cells. other hsa-mir-155 "Leukemia, Myeloid, Acute" 24708856 "This study provides evidence for an anti-leukaemic role for miR-155 in human FLT3-wildtype AML, by inducing cell apoptosis and myelomonocytic differentiation, which is in contrast to its previously hypothesized role as an oncogene. This highlights the complexity of gene regulation by microRNAs that may have tumour repressor or oncogenic effects depending on disease context or tissue type." other hsa-mir-375 Neoplasms [unspecific] 24708873 "Taken together, miR-375-mediated suppression of multiple oncogenic components in HPV-associated carcinogenesis generates a cumulative biological response to rescue key tumor suppressors and diminish telomerase activity, which results in cell cycle arrest and cell proliferation inhibition." other hsa-mir-208b Heart Failure 24714087 "These results demonstrated that circulating miR-208b and miR-34a could be useful biomarkers for predicting left ventricular remodeling after AMI, and the miRNA levels are associated with increased risk of mortality or heart failure." other hsa-mir-34a Heart Failure 24714087 "These results demonstrated that circulating miR-208b and miR-34a could be useful biomarkers for predicting left ventricular remodeling after AMI, and the miRNA levels are associated with increased risk of mortality or heart failure." other hsa-mir-451 Glioma 24714982 Selective ¦Â2 adrenergic agonist increases Cx43 and miR-451 expression via cAMP-Epac. other hsa-mir-22 "Carcinoma, Endometrial" 24715036 miR-22 inhibits proliferation and invasion in estrogen receptor ¦Á-positive endometrial endometrioid carcinomas cells. other hsa-mir-210 "Carcinoma, Ovarian" 24715221 Hypoxia-induced miR-210 in epithelial ovarian cancer enhances cancer cell viability via promoting proliferation and inhibiting apoptosis. other hsa-mir-130b Prostate Neoplasms 24715691 "In addition to downregulation of the large tumor suppressor homolog2 and the programmed cell death protein 4, a neoplastic transformation inhibitor, the tumorigenic reprogramming of pASCs was associated with trafficking by PC cell-derived exosomes of oncogenic factors, including H-ras and K-ras transcripts, oncomiRNAs miR-125b, miR-130b, and miR-155 as well as the Ras superfamily of GTPases Rab1a, Rab1b, and Rab11a." other hsa-mir-155 Neoplasms [unspecific] 24716910 "MiR-421, miR-155 and miR-650: emerging trends of regulation of cancer and apoptosis." other hsa-mir-421 Neoplasms [unspecific] 24716910 "MiR-421, miR-155 and miR-650: emerging trends of regulation of cancer and apoptosis." other hsa-mir-650 Neoplasms [unspecific] 24716910 "MiR-421, miR-155 and miR-650: emerging trends of regulation of cancer and apoptosis." other hsa-mir-375 Gastric Neoplasms 24718681 miR-375 inhibits Helicobacter pylori-induced gastric carcinogenesis by blocking JAK2-STAT3 signaling. other hsa-mir-214 "Carcinoma, Hepatocellular" 24719559 "Addition of NCTD to treat RAW264.7 or TAMs enhanced M1 polarization through increase of miR-214 expression. NCTD significantly inhibited β-catenin expression, which could be reversed by miR-214 inhibitor." other hsa-mir-210 "Leukemia, Lymphoblastic, Acute, Childhood" 24720529 Effect of microRNA-210 on prognosis and response to chemotherapeutic drugs in pediatric acute lymphoblastic leukemia. other hsa-mir-122 Hepatitis C Virus Infection 24721497 Hepatitis C virus and human miR-122: insights from the bench to the clinic. other hsa-mir-34a "Carcinoma, Skin" 24726431 Our results demonstrate that p53 mutations increase apoptotic resistance in keratinocytes by interfering with miR-34a-mediated regulation of SIRT1 expression. other hsa-mir-223 Breast Neoplasms 24727437 Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner. other hsa-mir-20a Neoplasms [unspecific] 24732804 "Decreased expression of miR-27a/miR-20a:miR-17-5p by PEITC-induced ROS is a key step in triggering the miR-ZBTB Sp cascade leading to downregulation of Sp TFs, and this is due to ROS-dependent epigenetic effects associated with genome-wide shifts in repressor complexes, resulting in decreased expression of Myc and the Myc-regulated miRs." other hsa-mir-155 Selective IgE Deficiency Disease 24734904 miRNA-155 controls mast cell activation by regulating the PI3K¦Ã pathway and anaphylaxis in a mouse model. other hsa-mir-135b "Carcinoma, Colon" 24735923 MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer. other hsa-mir-155 Recurrent Spontaneous Abortion 24739646 "The expression of miR-155 and HIF-1¦Á is topically stimulated by oxygen signal.HIF-1¦Á adjusts the transcription and translation of VEGF, which together involved in placental trophoblast invasion and placental angiogenesis.The low expression of miR-155 could interfere with expression of HIF-1¦Á and VEGF,which might be involved in villous vascular dysplasia in URSA." other hsa-mir-133b Parkinson Disease 24742361 Orchestrated increase of dopamine and PARK mRNAs but not miR-133b in dopamine neurons in Parkinson's disease. other hsa-mir-21 Cardiomegaly 24743143 "In particular, a passenger strand miR, miR-21*, was identified as a potent paracrine factor that induces cardiomyocyte hypertrophy when shuttled through exosomes." other hsa-mir-21 Heart Failure 24743143 "In particular, a passenger strand miR, miR-21*, was identified as a potent paracrine factor that induces cardiomyocyte hypertrophy when shuttled through exosomes." other hsa-mir-146a Graves Ophthalmopathy 24743332 Increased microRNA-155 and decreased microRNA-146a may promote ocular inflammation and proliferation in Graves' ophthalmopathy. other hsa-mir-155 Graves Ophthalmopathy 24743332 Increased microRNA-155 and decreased microRNA-146a may promote ocular inflammation and proliferation in Graves' ophthalmopathy. other hsa-mir-491 Glioblastoma 24747968 Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma. other hsa-mir-122 "Carcinoma, Hepatocellular, HBV-Related" 24748463 Association of miRNA-122-binding site polymorphism at the interleukin-1 ¦Á gene and its interaction with hepatitis B virus mutations with hepatocellular carcinoma risk. other hsa-mir-122 Chronic Hepatitis C 24752012 HMOX1 and miR-122 play an important role in the pathogenesis of CHC in HCV mono-and HIV/HCV co-infected patients. Reduced expression of HMOX1 in patients with HIV/HCV co-infection may indicate a worse prognosis in this group. Our results do not support the importance of Bach-1 in repression of HMOX1 in patients with chronic hepatitis C. other hsa-mir-200c Breast Neoplasms 24754877 Glabridin attenuates the migratory and invasive capacity of breast cancer cells by activating microRNA-200c. other hsa-mir-23b Neoplasms [unspecific] 24755453 Regulation of miR-23b expression and its dual role on ROS production and tumour development. other hsa-mir-101 "Carcinoma, Hepatocellular" 24759835 "In human HCC, COX-2 mRNA but not COX-2 protein levels are associated with expression levels of angiogenic factors. MiR-21 levels are not associated with angiogenic molecules. MiR-16 and miR-101 levels do not correlate with COX-2 mRNA and protein levels." other hsa-mir-16 "Carcinoma, Hepatocellular" 24759835 "In human HCC, COX-2 mRNA but not COX-2 protein levels are associated with expression levels of angiogenic factors. MiR-21 levels are not associated with angiogenic molecules. MiR-16 and miR-101 levels do not correlate with COX-2 mRNA and protein levels." other hsa-mir-21 "Carcinoma, Hepatocellular" 24759835 "In human HCC, COX-2 mRNA but not COX-2 protein levels are associated with expression levels of angiogenic factors. MiR-21 levels are not associated with angiogenic molecules. MiR-16 and miR-101 levels do not correlate with COX-2 mRNA and protein levels." other hsa-mir-143 Osteosarcoma 24762226 Propofol inhibits proliferation and invasion of osteosarcoma cells by regulation of microRNA-143 expression. other hsa-mir-29b "Carcinoma, Ovarian" 24767251 Involvement of miR-29b signaling in the sensitivity to chemotherapy in patients with ovarian carcinoma. other hsa-mir-155 Atherosclerosis 24767942 We hypothesized that native LDL and oxidized LDL played a key role in modulating the effects of miR-155 on macrophages at different stages of atherosclerosis. other hsa-mir-552 "Adenocarcinoma, Lung" 24778034 "MicroRNA profiles predict the histology of primary lung carcinomas,and differentiate between primary lung adenocarcinomas and colorectal cancer metastases." other hsa-mir-552 Colorectal Carcinoma 24778034 "MicroRNA profiles predict the histology of primary lung carcinomas,and differentiate between primary lung adenocarcinomas and colorectal cancer metastases." other hsa-mir-592 "Adenocarcinoma, Lung" 24778034 "MicroRNA profiles predict the histology of primary lung carcinomas,and differentiate between primary lung adenocarcinomas and colorectal cancer metastases." other hsa-mir-592 Colorectal Carcinoma 24778034 "MicroRNA profiles predict the histology of primary lung carcinomas,and differentiate between primary lung adenocarcinomas and colorectal cancer metastases." other hsa-mir-125b Rheumatoid Arthritis 24778468 Circulating miRNA-125b is a potential biomarker predicting response to rituximab in rheumatoid arthritis. other hsa-mir-31 "Carcinoma, Endometrial" 24779718 MIR31 functions as an oncogene in endometrial cancer by repressing the Hippo pathway. MIR31 is a potential new molecular marker for predicting the risk of recurrence and prognosis of endometrial cancer. other hsa-mir-21 Colorectal Carcinoma 24780321 Correlation of over-expressions of miR-21 and Notch-1 in human colorectal cancer with clinical stages. other hsa-mir-223 Osteosarcoma 24784921 Prognostic value of microRNA-223/epithelial cell transforming sequence 2 signaling in patients with osteosarcoma. other hsa-mir-224 Glioblastoma 24785373 MiR-224 expression increases radiation sensitivity of glioblastoma cells. other hsa-mir-26a Lung Neoplasms 24788552 MicroRNA-26a involved in Toll-like receptor 9-mediated lung cancer growth and migration. other hsa-mir-126 "Squamous Cell Carcinoma, Oral" 24789258 Suppressive effect of microRNA-126 on oral squamous cell carcinoma in vitro. other hsa-mir-486 Muscular Dystrophy 24789910 MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms. other hsa-let-7g "Carcinoma, Hepatocellular" 24791593 Let-7g microRNA sensitizes fluorouracil-resistant human hepatoma cells. other hsa-mir-96 "Squamous Cell Carcinoma, Cerevial" 24791792 Expressions of MicroRNA-96 before and after chemotherapy and its relationship with chemosensitivity in cervical squamous cell carcinoma. other hsa-mir-200c Lung Neoplasms 24791940 Therapeutic delivery of miR-200c enhances radiosensitivity in lung cancer. other hsa-mir-10b "Carcinoma, Renal Cell, Clear-Cell" 24793999 The miR(21/10b) ratio as a prognostic marker in clear cell renal cell carcinoma. other hsa-mir-21 "Carcinoma, Renal Cell, Clear-Cell" 24793999 The miR(21/10b) ratio as a prognostic marker in clear cell renal cell carcinoma. other hsa-mir-126 Essential Hypertension 24794206 MicroRNA-9 and microRNA-126 expression levels in patients with essential hypertension: potential markers of target-organ damage. other hsa-mir-9 Essential Hypertension 24794206 MicroRNA-9 and microRNA-126 expression levels in patients with essential hypertension: potential markers of target-organ damage. other hsa-mir-224 Gastric Neoplasms 24796455 Effect of antisense miR-224 on gastric cancer cell proliferation and apoptosis. other hsa-mir-34a "Carcinoma, Gastric" 24796666 The RNA-binding protein PCBP2 facilitates gastric carcinoma growth by targeting miR-34a. other hsa-mir-29 "Carcinoma, Hepatocellular" 24798303 Modulation of miR-29 expression by ¦Á-fetoprotein is linked to the hepatocellular carcinoma epigenome. other hsa-mir-24 "Carcinoma, Hepatocellular" 24800232 MicroRNA-24 modulates aflatoxin B1-related hepatocellular carcinoma prognosis and tumorigenesis. other hsa-mir-34c Osteosarcoma 24802328 MiR-34c inhibits osteosarcoma metastasis and chemoresistance. other hsa-mir-148a "Carcinoma, Hepatocellular" 24806207 The repressive effect of miR-148a on TGF beta-SMADs signal pathway is involved in the glabridin-induced inhibition of the cancer stem cells-like properties in hepatocellular carcinoma cells. other hsa-mir-23a "Carcinoma, Breast" 24806942 Downregulation of SP1 and increased miR-23a levels in MSCs after contact with tumor cell medium as well as enhanced TGFβ1 expression were identified as potential molecular regulators of CXCL12 activity in MSCs. other hsa-mir-133a Long QT Syndrome 24809446 MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and MiR-133A in long QT syndrome. other hsa-mir-141 "Carcinoma, Renal Cell" 24810210 Honokiol suppresses renal cancer cells' metastasis via dual-blocking epithelial-mesenchymal transition and cancer stem cell properties through modulating miR-141/ZEB2 signaling. other hsa-mir-199a "Carcinoma, Thyroid, Papillary" 24810336 miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma. other hsa-mir-200a "Diabetes Mellitus, Type 2" 24812635 "miR-448, let-7b, miR-540, miR-296, miR-880, miR-200a, miR-500, miR-10b, miR-336, miR-30d, miR-208, let-7e, miR-142-5p, miR-874, miR-375, miR-879, miR-501, and miR-188 were upregulated, while miR-301b, miR-134, and miR-652 were downregulated in TMH group." other hsa-mir-375 "Diabetes Mellitus, Type 2" 24812635 "Through target gene analysis and real-time PCR verification, we found that these miRNAs, especially miR-375 and miR-30d, can stimulate insulin secretion in islet." other hsa-mir-1915 Colon Neoplasms 24814047 Tumor suppressor p53 induces miR-1915 processing to inhibit Bcl-2 in the apoptotic response to DNA damage. other hsa-mir-200 Osteosarcoma 24815002 Busulfan inhibits growth of human osteosarcoma through miR-200 family microRNAs in vitro and in vivo. other hsa-mir-34 Osteoporosis 24815299 "miR-34 has also been implicated in various non-cancerous diseases, such as brain disorders, osteoporosis, and cardiovascular complications." other hsa-mir-100 Atherosclerosis 24815336 The co-inertia approach in identification of specific microRNA in early and advanced atherosclerosis plaque. other hsa-mir-127 Atherosclerosis 24815336 The co-inertia approach in identification of specific microRNA in early and advanced atherosclerosis plaque. other hsa-mir-145 Atherosclerosis 24815336 The co-inertia approach in identification of specific microRNA in early and advanced atherosclerosis plaque. other hsa-mir-146 Atherosclerosis 24815336 The co-inertia approach in identification of specific microRNA in early and advanced atherosclerosis plaque. other hsa-mir-155 Atherosclerosis 24815336 The co-inertia approach in identification of specific microRNA in early and advanced atherosclerosis plaque. other hsa-mir-221 Atherosclerosis 24815336 The co-inertia approach in identification of specific microRNA in early and advanced atherosclerosis plaque. other hsa-mir-222 Atherosclerosis 24815336 The co-inertia approach in identification of specific microRNA in early and advanced atherosclerosis plaque. other hsa-mir-24 Atherosclerosis 24815336 The co-inertia approach in identification of specific microRNA in early and advanced atherosclerosis plaque. other hsa-mir-718 Ovarian Neoplasms 24815691 MiR-718 represses VEGF and inhibits ovarian cancer cell progression. other hsa-mir-223 Rheumatoid Arthritis 24816316 Increased miR-223 expression in T cells from patients with rheumatoid arthritis leads to decreased insulin-like growth factor-1-mediated interleukin-10 production. other hsa-mir-133a "Carcinoma, Lung, Non-Small-Cell" 24816813 MicroRNA-133a suppresses multiple oncogenic membrane receptors and cell invasion in non-small cell lung carcinoma. other hsa-mir-125b Glioblastoma 24817689 MicroRNA expression signatures and their correlation with clinicopathological features in glioblastoma multiforme other hsa-mir-125a Multiple Myeloma 24819167 A p53-dependent tumor suppressor network is induced by selective miR-125a-5p inhibition in multiple myeloma cells. other hsa-mir-223 Colorectal Carcinoma 24819398 MicroRNA-223 functions as an oncogene in human colorectal cancer cells. other hsa-mir-422a Osteoporosis 24820117 MiR-422a as a potential cellular microRNA biomarker for postmenopausal osteoporosis. other hsa-mir-27 Urinary Bladder Cancer 24821854 3'-Biotin-tagged microRNA-27 does not associate with Argonaute proteins in cells. other hsa-mir-31 Hepatitis B Virus Infection 24824126 HBsAg regulation of miR-31 expression in HepG2 cells other hsa-mir-125a Hepatitis B Virus Infection 24824183 Functional interplay between hepatitis B virus X protein and human miR-125a in HBV infection. other hsa-mir-27a Hepatitis C Virus Infection 24824429 MicroRNA-27a modulates HCV infection in differentiated hepatocyte-like cells from adipose tissue-derived mesenchymal stem cells. other hsa-mir-22 "Leukemia, Lymphocytic, Chronic, B-Cell" 24825182 Activation of the PI3K/AKT pathway by microRNA-22 results in CLL B-cell proliferation. other hsa-mir-142 Glioma 24825189 MicroRNA 142-3p attenuates spread of replicating retroviral vector in hematopoietic lineage-derived cells while maintaining an antiviral immune response. other hsa-mir-320 "Diabetes Mellitus, Type 2" 24825548 Cardiomyocytes mediate anti-angiogenesis in type 2 diabetic rats through the exosomal transfer of miR-320 into endothelial cells. other hsa-mir-124 "Colitis, Ulcerative" 24825593 attenuation of ischemic and inflammatory injury in cardiomyocytes. other hsa-mir-21 Myocardial Ischemic-Reperfusion Injury 24825878 Na2S induces cardioprotective effects through miR-21-dependent attenuation of ischemic and inflammatory injury in cardiomyocytes. other hsa-mir-4728 Breast Neoplasms 24828673 "we present here an alternative mode of miRNA regulation and demonstrate this dual function of the HER2 locus, linking the two major biomarkers in breast cancer." other hsa-mir-509 Cystic Fibrosis 24829907 Exploitation of a very small peptide nucleic acid as a new inhibitor of miR-509-3p involved in the regulation of cystic fibrosis disease-gene expression. other hsa-mir-19 Breast Neoplasms 24831732 Curcumin modulates miR-19/PTEN/AKT/p53 axis to suppress bisphenol A-induced MCF-7 breast cancer cell proliferation. other hsa-mir-21 Colorectal Carcinoma 24832083 nuclear translocation of ¦Â-catenin increased by miR-21 promotes tumour malignancy and a poor outcome in APC-mutated patients but not in APC-wild-type colorectal cancer. other hsa-mir-221 Central Nervous System Embryonal Tumor 24832085 "Downregulation of SUN2, a novel tumor suppressor, mediates miR-221/222-induced malignancy in central nervous system embryonal tumors." other hsa-mir-222 Central Nervous System Embryonal Tumor 24832085 "Downregulation of SUN2, a novel tumor suppressor, mediates miR-221/222-induced malignancy in central nervous system embryonal tumors." other hsa-mir-134 Acute Myocardial Infarction 24833470 Predictive value of circulating miR-328 and miR-134 for acute myocardial infarction. other hsa-mir-328 Acute Myocardial Infarction 24833470 Predictive value of circulating miR-328 and miR-134 for acute myocardial infarction. other hsa-mir-126 Atherosclerosis 24833799 MicroRNA-126 in atherosclerosis other hsa-mir-765 Prostate Neoplasms 24837491 "Hsa-miRNA-765 as a key mediator for inhibiting growth, migration and invasion in fulvestrant-treated prostate cancer." other hsa-mir-155 Breast Neoplasms 24840899 Increased circulating microRNA-155 as a potential biomarker for breast cancer screening: a meta-analysis. other hsa-mir-451 "Carcinoma, Hepatocellular" 24841638 miR-451: potential role as tumor suppressor of human hepatoma cell growth and invasion. other hsa-mir-223 Colorectal Carcinoma 24841830 fecal miR-223 and miR-451 hold promise in detecting CRC. other hsa-mir-451 Colorectal Carcinoma 24841830 fecal miR-223 and miR-451 hold promise in detecting CRC. other hsa-mir-218 "Carcinoma, Cervical" 24843318 MicroRNA-218 enhances the radiosensitivity of human cervical cancer via promoting radiation induced apoptosis. other hsa-mir-122 Hepatitis C Virus Infection 24844965 "Different types of IFN increase the expression of miRNAs that inhibit HCV replication and decrease the expression of miRNA-122 that supports HCV replication. Thus the regulation of HCV replication-related miRNA expression is a general anti-HCV mechanism by different types of IFN. However, the regulation pattern by type II IFN is different from those by other types of IFNs,implying that type II IFN has different anti-HCV mechanisms from other types of IFN at miRNA level." other hsa-mir-21 "Carcinoma, Hepatocellular" 24845419 Dehydroepiandrosterone-induces miR-21 transcription in HepG2 cells through estrogen receptor ¦Â and androgen receptor. other hsa-mir-497 Gastric Neoplasms 24845562 The putative tumor suppressor microRNA-497 modulates gastric cancer cell proliferation and invasion by repressing eIF4E. other hsa-mir-128 "Leukemia, Myeloid, Acute" 24846063 Effect of miR-128 in DNA damage of HL-60 acute myeloid leukemia cells. other hsa-mir-106b "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 24846066 "miR-21, miR-106b and miR-375 as novel potential biomarkers for laryngeal squamous cell carcinoma." other hsa-mir-21 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 24846066 "miR-21, miR-106b and miR-375 as novel potential biomarkers for laryngeal squamous cell carcinoma." other hsa-mir-375 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 24846066 "miR-21, miR-106b and miR-375 as novel potential biomarkers for laryngeal squamous cell carcinoma." other hsa-mir-200a Cervix Endometrial Stromal Tumor 24850415 "MicroRNA-200a locally attenuates progesterone signaling in the cervix, preventing embryo implantation." other hsa-mir-26a Idiopathic Pulmonary Fibrosis 24853416 Integrated analyses identify the involvement of microRNA-26a in epithelial-mesenchymal transition during idiopathic pulmonary fibrosis. other hsa-let-7a Salivary Gland Neoplasms 24853424 "Furthermore, WIF1 significantly increased the expression of microRNAs pri-let-7a and pri-miR-200c, negative regulators of stemness and cancer progression." other hsa-mir-24 Ischemia-Reperfusion Injury 24854275 MicroRNA-24 antagonism prevents renal ischemia reperfusion injury. other hsa-mir-127 "Carcinoma, Hepatocellular" 24854842 miR-127 plays a tumor-suppressor role and can serve as a potential diagnostic biomarker for HCC. other hsa-mir-200a Meningioma 24858044 miR-200a-mediated suppression of non-muscle heavy chain IIb inhibits meningioma cell migration and tumor growth in vivo. other hsa-mir-142 "Leukemia, Myeloid, Acute" 24858343 The protein phosphatase 2A regulatory subunit B55¦Á is a modulator of signaling and microRNA expression in acute myeloid leukemia cells. other hsa-mir-191 "Leukemia, Myeloid, Acute" 24858343 The protein phosphatase 2A regulatory subunit B55¦Á is a modulator of signaling and microRNA expression in acute myeloid leukemia cells. other hsa-mir-122 Glioma 24863942 MiR-122/Wnt/¦Â-catenin regulatory circuitry sustains glioma progression. other hsa-mir-23 Myocardial Infarction 24864093 MicroRNA--a new diagnostic tool in coronary artery disease and myocardial infarction. other hsa-mir-103a Breast Neoplasms 24865188 "Association of microRNA-93, 190, 200b and receptor status in core biopsies from stage III breast cancer patients." other hsa-mir-190a "Carcinoma, Breast, Triple Negative" 24865188 "Association of microRNA-93, 190, 200b and receptor status in core biopsies from stage III breast cancer patients." other hsa-mir-200b "Carcinoma, Breast, Triple Negative" 24865188 "Association of microRNA-93, 190, 200b and receptor status in core biopsies from stage III breast cancer patients." other hsa-mir-93 "Carcinoma, Breast, Triple Negative" 24865188 "Association of microRNA-93, 190, 200b and receptor status in core biopsies from stage III breast cancer patients." other hsa-mir-21 Ovarian Neoplasms 24865582 Upregulation of miR-21 in cisplatin resistant ovarian cancer via JNK-1/c-Jun pathway. other hsa-mir-181c Brain Neoplasms 24867100 MiRNA-181c inhibits EGFR-signaling-dependent MMP9 activation via suppressing Akt phosphorylation in glioblastoma. other hsa-mir-126 Atherosclerosis 24870014 These effects may explain the ability of pitavastatin to reduce the progression of atherosclerosis. The findings further suggest that inhibitory effect of pitavastatin on VCAM-1 is not related to miR-126 but depends on other ways. other hsa-mir-122 Hepatitis C Virus Infection 24871972 "Representatively, miR-122 directly modulates the HCV life cycle by increasing HCV translation and genomic RNA stability." other hsa-mir-196a Human Immunodeficiency Virus Infection 24872081 Involvement of miR-196a in HIV-associated neurocognitive disorders. other hsa-mir-17 Leukemia 24872388 Inhibition of miR-17 and miR-20a by oridonin triggers apoptosis and reverses chemoresistance by derepressing BIM-S. other hsa-mir-20a Leukemia 24872388 Inhibition of miR-17 and miR-20a by oridonin triggers apoptosis and reverses chemoresistance by derepressing BIM-S. other hsa-mir-10b "Carcinoma, Hepatocellular" 24875649 the study reveals the comprehensive miRNome of hepatic tissue and provides new tools for investigation of microRNA dependent pathways in cirrhotic liver and hepatocellular carcinoma. This article is part of a Directed Issue entitled: Rare Cancers. other hsa-mir-1269a "Carcinoma, Hepatocellular" 24875649 the study reveals the comprehensive miRNome of hepatic tissue and provides new tools for investigation of microRNA dependent pathways in cirrhotic liver and hepatocellular carcinoma. This article is part of a Directed Issue entitled: Rare Cancers. other hsa-mir-183 "Carcinoma, Hepatocellular" 24875649 the study reveals the comprehensive miRNome of hepatic tissue and provides new tools for investigation of microRNA dependent pathways in cirrhotic liver and hepatocellular carcinoma. This article is part of a Directed Issue entitled: Rare Cancers. other hsa-mir-199a "Carcinoma, Hepatocellular" 24875649 the study reveals the comprehensive miRNome of hepatic tissue and provides new tools for investigation of microRNA dependent pathways in cirrhotic liver and hepatocellular carcinoma. This article is part of a Directed Issue entitled: Rare Cancers. other hsa-mir-199b "Carcinoma, Hepatocellular" 24875649 the study reveals the comprehensive miRNome of hepatic tissue and provides new tools for investigation of microRNA dependent pathways in cirrhotic liver and hepatocellular carcinoma. This article is part of a Directed Issue entitled: Rare Cancers. other hsa-mir-214 "Carcinoma, Hepatocellular" 24875649 the study reveals the comprehensive miRNome of hepatic tissue and provides new tools for investigation of microRNA dependent pathways in cirrhotic liver and hepatocellular carcinoma. This article is part of a Directed Issue entitled: Rare Cancers. other hsa-mir-3144 "Carcinoma, Hepatocellular" 24875649 the study reveals the comprehensive miRNome of hepatic tissue and provides new tools for investigation of microRNA dependent pathways in cirrhotic liver and hepatocellular carcinoma. This article is part of a Directed Issue entitled: Rare Cancers. other hsa-mir-490 "Carcinoma, Hepatocellular" 24875649 the study reveals the comprehensive miRNome of hepatic tissue and provides new tools for investigation of microRNA dependent pathways in cirrhotic liver and hepatocellular carcinoma. This article is part of a Directed Issue entitled: Rare Cancers. other hsa-mir-106b "Carcinoma, Hepatocellular" 24876719 miR-106b-25/miR-17-92 clusters: polycistrons with oncogenic roles in hepatocellular carcinoma. other hsa-mir-17 "Carcinoma, Hepatocellular" 24876719 miR-106b-25/miR-17-92 clusters: polycistrons with oncogenic roles in hepatocellular carcinoma. other hsa-mir-18 "Carcinoma, Hepatocellular" 24876719 miR-106b-25/miR-17-92 clusters: polycistrons with oncogenic roles in hepatocellular carcinoma. other hsa-mir-19a "Carcinoma, Hepatocellular" 24876719 miR-106b-25/miR-17-92 clusters: polycistrons with oncogenic roles in hepatocellular carcinoma. other hsa-mir-19b-1 "Carcinoma, Hepatocellular" 24876719 miR-106b-25/miR-17-92 clusters: polycistrons with oncogenic roles in hepatocellular carcinoma. other hsa-mir-20a "Carcinoma, Hepatocellular" 24876719 miR-106b-25/miR-17-92 clusters: polycistrons with oncogenic roles in hepatocellular carcinoma. other hsa-mir-92-1 "Carcinoma, Hepatocellular" 24876719 miR-106b-25/miR-17-92 clusters: polycistrons with oncogenic roles in hepatocellular carcinoma. other hsa-mir-1291 Acute Myocardial Infarction 24885383 "This study demonstrated that the levels of miR-133, miR-1291 and miR-663b are associated with AMI. The potential of these miRNAs as biomarkers to improve patient stratification according to the risk of AMI and as circulating biomarkers for the AMI progonos warrants further study." other hsa-mir-133 Acute Myocardial Infarction 24885383 "This study demonstrated that the levels of miR-133, miR-1291 and miR-663b are associated with AMI. The potential of these miRNAs as biomarkers to improve patient stratification according to the risk of AMI and as circulating biomarkers for the AMI progonos warrants further study." other hsa-mir-663b Acute Myocardial Infarction 24885383 "This study demonstrated that the levels of miR-133, miR-1291 and miR-663b are associated with AMI. The potential of these miRNAs as biomarkers to improve patient stratification according to the risk of AMI and as circulating biomarkers for the AMI progonos warrants further study." other hsa-mir-520b Hepatitis B Virus Infection 24886421 HBx accelerates hepatocarcinogenesis with partner survivin through modulating tumor suppressor miR-520b and oncoprotein HBXIP. other hsa-mir-221 Breast Neoplasms 24886939 miR-221/222 promotes S-phase entry and cellular migration in control of basal-like breast cancer. other hsa-mir-222 Breast Neoplasms 24886939 miR-221/222 promotes S-phase entry and cellular migration in control of basal-like breast cancer. other hsa-mir-940 Tetralogy Of Fallot 24889693 miRNA-940 reduction contributes to human Tetralogy of Fallot development. other hsa-mir-15b "Carcinoma, Pancreatic" 24892299 Expression of microRNA-15b and the glycosyltransferase GCNT3 correlates with antitumor efficacy of Rosemary diterpenes in colon and pancreatic cancer. other hsa-mir-15b Colon Neoplasms 24892299 Expression of microRNA-15b and the glycosyltransferase GCNT3 correlates with antitumor efficacy of Rosemary diterpenes in colon and pancreatic cancer. other hsa-mir-146a "Carcinoma, Hepatocellular" 24895573 Synergistic effect of MiR-146a mimic and cetuximab on hepatocellular carcinoma cells. other hsa-mir-24 Pancreatic Neoplasms 24895587 The miR-24 was the most significantly powerful miRNA that regulated series of important genes. other hsa-mir-16 Colorectal Carcinoma 24895601 "Our results have laid down a solid foundation in exploration of novel CRC mechanisms, and identification of miRNA roles as oncomirs or tumor suppressor mirs in CRC." other hsa-mir-148a Pancreatic Neoplasms 24895996 miR-148a- and miR-216a-regulated oncolytic adenoviruses targeting pancreatic tumors attenuate tissue damage without perturbation of miRNA activity. other hsa-mir-216a Pancreatic Neoplasms 24895996 miR-148a- and miR-216a-regulated oncolytic adenoviruses targeting pancreatic tumors attenuate tissue damage without perturbation of miRNA activity. other hsa-mir-125a "Carcinoma, Nasopharyngeal" 24896104 Curcumin exerts inhibitory effects on undifferentiated nasopharyngeal carcinoma by inhibiting the expression of miR-125a-5p. other hsa-mir-10b Breast Neoplasms 24897960 Our results provide evidences that the addition of miR-10b RERs to the prognostic factors used in clinical routine could improve the prediction abilities for both overall mortality and disease progression in breast cancer patients. other hsa-mir-16 Multiple Sclerosis 24898268 "Further evidence indicated that DIM treatment significantly upregulated several miRNAs (miR-200c, miR-146a, miR-16, miR-93, and miR-22) in brain CD4(+) T cells during EAE while suppressing their associated target genes." other hsa-mir-122 "Carcinoma, Colon" 24898807 Overexpression of microRNA-122 re-sensitizes 5-FU-resistant colon cancer cells to 5-FU through the inhibition of PKM2 in vitro and in vivo. other hsa-mir-23a "Carcinoma, Lung, Non-Small-Cell" 24898878 There is an interaction between miR-23a and IRS-1 in the modulation of the migration and invasion of NSCLC cells. IRS-1 is variably expressed in NSCLC patients and correlates with NSCLC patient survival. other hsa-mir-451 Glioblastoma 24899919 Those parameters are primarily linked to the reactions that involve the microRNA-451 and the thereof regulated protein MO25. other hsa-mir-17 Multiple Sclerosis 24901013 Unraveling natalizumab effects on deregulated miR-17 expression in CD4+ T cells of patients with relapsing-remitting multiple sclerosis. other hsa-mir-125a Obesity 24901105 Our results support the involvement of miR-125a-3p in regulating the insulin signalling pathway and imply that increased miR- 125a-3p expression in omental adipose tissues may be a characteristic feature of insulin resistance in obese men. other hsa-mir-18a Ischemic Heart Disease 24903055 PNS treatment resulted in reduced expression of miR-18a in tumor and upregulated expression of miR-18a in heart. other hsa-mir-100 Neoplasms [unspecific] 24903380 "the prognostic role of miR-100 in human cancers, and thus, much more works are needed in this field." other hsa-mir-221 Breast Neoplasms 24905916 Trail resistance induces epithelial-mesenchymal transition and enhances invasiveness by suppressing PTEN via miR-221 in breast cancer. other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 24906642 Downregulation of miR-21 increases cisplatin sensitivity of non-small-cell lung cancer. other hsa-mir-210 Neoplasms [unspecific] 24909053 Multiple functions of hypoxia-regulated miR-210 in cancer. other hsa-mir-630 Neoplasms [unspecific] 24909689 E2F1-regulated DROSHA promotes miR-630 biosynthesis in cisplatin-exposed cancer cells. other hsa-mir-124 Colorectal Carcinoma 24909917 KITENIN-targeting microRNA-124 suppresses colorectal cancer cell motility and tumorigenesis. other hsa-mir-27a Colorectal Carcinoma 24909917 KITENIN-targeting microRNA-124 suppresses colorectal cancer cell motility and tumorigenesis. other hsa-mir-30b Colorectal Carcinoma 24909917 KITENIN-targeting microRNA-124 suppresses colorectal cancer cell motility and tumorigenesis. other hsa-let-7i Acute Ischemic Stroke 24911610 "Several miRNA are differentially expressed in blood cells of patients with acute ischemic stroke. These miRNA may regulate leukocyte gene expression in ischemic stroke including pathways involved in immune activation,leukocyte extravasation and thrombosis." other hsa-mir-21 Neoplasms [unspecific] 24912785 Exosomal miR-21 derived from arsenite-transformed human bronchial epithelial cells promotes cell proliferation associated with arsenite carcinogenesis. other hsa-mir-124 Prostate Neoplasms 24913567 "It was clear that PACE4 level was closely associated with malignancy and invasiveness of PCa in vivo or in vitro MiR-124, played a crucial role inhibiting PACE4 transcription thus exhibiting obvious effects of antiproliferation and antiaggression of PCa." other hsa-mir-581 "Carcinoma, Hepatocellular" 24913918 miR-581 during hepatocarcinogenesis may lead to a reduction in HBsAg expression and impede HCC development. other hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 24914134 MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia. other hsa-mir-132 Colorectal Carcinoma 24914372 Our study indicated that miR-132 plays an important role in the invasion and metastasis of CRC. other hsa-mir-146a Neurodegenerative Diseases [unspecific] 24917789 "These findings together with the reduced expression of microRNA (miR)-124, and miR-155, decreased autophagy, enhanced senescence associated beta-galactosidase activity and elevated miR-146a expression, are suggestive that 16 DIV cells mainly correspond to irresponsive/senescent microglia." other hsa-mir-146a Cholangiocarcinoma 24918778 "Significant variability was observed in the temporal function of all six miRNAs, which may play an important role in the development of CCA." other hsa-mir-155 Cholangiocarcinoma 24918778 "Significant variability was observed in the temporal function of all six miRNAs, which may play an important role in the development of CCA." other hsa-mir-200a Cholangiocarcinoma 24918778 "Significant variability was observed in the temporal function of all six miRNAs, which may play an important role in the development of CCA." other hsa-mir-200b Cholangiocarcinoma 24918778 "Significant variability was observed in the temporal function of all six miRNAs, which may play an important role in the development of CCA." other hsa-mir-21 Cholangiocarcinoma 24918778 "Significant variability was observed in the temporal function of all six miRNAs, which may play an important role in the development of CCA." other hsa-mir-221 Cholangiocarcinoma 24918778 "Significant variability was observed in the temporal function of all six miRNAs, which may play an important role in the development of CCA." other hsa-mir-17 Melanoma 24920276 Differential regulation of aggressive features in melanoma cells by members of the miR-17-92 complex. other hsa-mir-18 Melanoma 24920276 Differential regulation of aggressive features in melanoma cells by members of the miR-17-92 complex. other hsa-mir-19a Melanoma 24920276 Differential regulation of aggressive features in melanoma cells by members of the miR-17-92 complex. other hsa-mir-19b-1 Melanoma 24920276 Differential regulation of aggressive features in melanoma cells by members of the miR-17-92 complex. other hsa-mir-20a Melanoma 24920276 Differential regulation of aggressive features in melanoma cells by members of the miR-17-92 complex. other hsa-mir-92-1 Melanoma 24920276 Differential regulation of aggressive features in melanoma cells by members of the miR-17-92 complex. other hsa-mir-103 Hematologic Neoplasms 24921248 could discriminate between colorectal recurrences to lymph nodes and liver and between colorectal liver metastasis and primary hepatic tumor. other hsa-mir-21 Hematologic Neoplasms 24921248 could discriminate between colorectal recurrences to lymph nodes and liver and between colorectal liver metastasis and primary hepatic tumor. other hsa-mir-31 Hematologic Neoplasms 24921248 could discriminate between colorectal recurrences to lymph nodes and liver and between colorectal liver metastasis and primary hepatic tumor. other hsa-mir-566 Hematologic Neoplasms 24921248 could discriminate between colorectal recurrences to lymph nodes and liver and between colorectal liver metastasis and primary hepatic tumor. other hsa-mir-93 Hematologic Neoplasms 24921248 could discriminate between colorectal recurrences to lymph nodes and liver and between colorectal liver metastasis and primary hepatic tumor. other hsa-mir-222 Breast Neoplasms 24923427 "Overall, this study suggested that both celecoxib and aspirin could prevent breast cancer growth by regulating proteins in the cell cycle and apoptosis without blocking estrogen synthesis. Besides, celecoxib might affect miR expression in an undesirable fashion." other hsa-mir-378 Obesity 24923530 Insight into the effects of adipose tissue inflammation factors on miR-378 expression and the underlying mechanism. other hsa-mir-106b Atrial Fibrillation 24927531 "miR-17-92 and miR-106b-25 directly repress genes, such as Shox2 and Tbx3, that are required for sinoatrial node development.Together, to our knowledge, these findings provide the first genetic evidence for an miR loss-of-function that increases atrial fibrillation susceptibility." other hsa-mir-33a Hyperlipidemia 24928089 "all selected miRNAs were detected in α-lipoprotein fraction from sera, and miR-33a was also present in β-lipoprotein fraction;" other hsa-mir-188 Osteoarthritis 24928913 "In IL-1β-stimulated human chondrocytes, chosen as a model of differentiated phenotype loss implicating the PPi transporter ANK, miR-9, miR-188 and let7e levels increased." other hsa-mir-19a Ovarian Neoplasms 24929208 miR-19a was also transported via TnTs connecting transfected K7M2 cells and nontransfected stromal MC3T3 murine osteoblast cells. other hsa-mir-146b Obesity 24931160 MiR-146b is a regulator of human visceral preadipocyte proliferation and differentiation and its expression is altered in human obesity. other hsa-mir-126 Atherosclerosis 24933211 "Furthermore, significantly increased aortic expression of miR-26a, miR-21, miR-126a, miR-132, miR-146 and miR-155 and decreased expression of miR-20a and miR-92a were observed in the vehicle-treated ApoE-/- mice. While NR1 treatment led to a significant reduction in the expression of miR-21, miR-26a, miR-126 and increased expression of miR-20a." other hsa-mir-155 Atherosclerosis 24933211 "Furthermore, significantly increased aortic expression of miR-26a, miR-21, miR-126a, miR-132, miR-146 and miR-155 and decreased expression of miR-20a and miR-92a were observed in the vehicle-treated ApoE-/- mice. While NR1 treatment led to a significant reduction in the expression of miR-21, miR-26a, miR-126 and increased expression of miR-20a." other hsa-mir-20a Atherosclerosis 24933211 "Furthermore, significantly increased aortic expression of miR-26a, miR-21, miR-126a, miR-132, miR-146 and miR-155 and decreased expression of miR-20a and miR-92a were observed in the vehicle-treated ApoE-/- mice. While NR1 treatment led to a significant reduction in the expression of miR-21, miR-26a, miR-126 and increased expression of miR-20a." other hsa-mir-133a Hypertension 24937684 "These results suggest that high salt intervention could down-regulate the expression of myocardial microRNA-133a, which may be one of the mechanisms involved in myocardial fibrosis in salt-sensitive hypertension." other hsa-mir-155 Down Syndrome 24938108 "Analysis of mtDNA, miR-155 and BACH1 expression in hearts from donors with and without Down syndrome." other hsa-mir-145 Colorectal Adenocarcinoma 24938624 This might be attributable to the fact that effects of miRNA activity may oscillate between gene product repression and activation. other hsa-mir-21 Colorectal Adenocarcinoma 24938624 This might be attributable to the fact that effects of miRNA activity may oscillate between gene product repression and activation. other hsa-mir-146a Osteoarthritis 24939082 Role of miR-146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitro. other hsa-mir-675 "Carcinoma, Hepatocellular" 24939300 inhibition of LncRNAH19 and miR-675 expression can promote migration and invasion of HCC cells via AKT/GSK-3¦Â/Cdc25A signaling pathway. other hsa-let-7a Breast Neoplasms 24942235 Expression status of let-7a and miR-335 among breast tumors in patients with and without germ-line BRCA mutations. other hsa-mir-335 Breast Neoplasms 24942235 Expression status of let-7a and miR-335 among breast tumors in patients with and without germ-line BRCA mutations. other hsa-mir-139 Colorectal Carcinoma 24942287 Post-transcriptional regulation of the tumor suppressor miR-139-5p and a network of miR-139-5p-mediated mRNA interactions in colorectal cancer. other hsa-mir-107 "Stroke, Ischemic" 24943094 Up-regulation of brain-enriched miR-107 promotes excitatory neurotoxicity through down-regulation of glutamate transporter-1 expression following ischaemic stroke. other hsa-mir-1 "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4). " other hsa-mir-103 "Diabetes Mellitus, Type 2" 24944010 "Insulin resistance, obesity, and hyperlipidemia (high lipid levels in the blood) have a strong connection with T2D and several miRNAs influence these clinical outcomes such as miR-143, miR-103, and miR-107, miR-29a, and miR-27b." other hsa-mir-107 "Diabetes Mellitus, Type 2" 24944010 "Insulin resistance, obesity, and hyperlipidemia (high lipid levels in the blood) have a strong connection with T2D and several miRNAs influence these clinical outcomes such as miR-143, miR-103, and miR-107, miR-29a, and miR-27b." other hsa-mir-124a "Diabetes Mellitus, Type 2" 24944010 "The influence of miRNAs (miR-7, miR-124a, miR-9, miR-96, miR-15a/b, miR-34a, miR-195, miR-376, miR-103, miR-107, and miR-146) in insulin secretion and beta (β) cell development has been well discussed." other hsa-mir-126 "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4). " other hsa-mir-128a "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4). " other hsa-mir-133a "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-133b "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-143 "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-145 "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-146 "Diabetes Mellitus, Type 2" 24944010 "The influence of miRNAs (miR-7, miR-124a, miR-9, miR-96, miR-15a/b, miR-34a, miR-195, miR-376, miR-103, miR-107, and miR-146) in insulin secretion and beta (β) cell development has been well discussed." other hsa-mir-15a "Diabetes Mellitus, Type 2" 24944010 "The influence of miRNAs (miR-7, miR-124a, miR-9, miR-96, miR-15a/b, miR-34a, miR-195, miR-376, miR-103, miR-107, and miR-146) in insulin secretion and beta (β) cell development has been well discussed." other hsa-mir-15b "Diabetes Mellitus, Type 2" 24944010 "The influence of miRNAs (miR-7, miR-124a, miR-9, miR-96, miR-15a/b, miR-34a, miR-195, miR-376, miR-103, miR-107, and miR-146) in insulin secretion and beta (β) cell development has been well discussed." other hsa-mir-181b "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-195 "Diabetes Mellitus, Type 2" 24944010 "The influence of miRNAs (miR-7, miR-124a, miR-9, miR-96, miR-15a/b, miR-34a, miR-195, miR-376, miR-103, miR-107, and miR-146) in insulin secretion and beta (β) cell development has been well discussed." other hsa-mir-21 "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-223 "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-27b "Diabetes Mellitus, Type 2" 24944010 "Insulin resistance, obesity, and hyperlipidemia (high lipid levels in the blood) have a strong connection with T2D and several miRNAs influence these clinical outcomes such as miR-143, miR-103, and miR-107, miR-29a, and miR-27b" other hsa-mir-29 "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-29a "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-320 "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-33a "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-33b "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-34a "Diabetes Mellitus, Type 2" 24944010 "The influence of miRNAs (miR-7, miR-124a, miR-9, miR-96, miR-15a/b, miR-34a, miR-195, miR-376, miR-103, miR-107, and miR-146) in insulin secretion and beta (β) cell development has been well discussed." other hsa-mir-376 "Diabetes Mellitus, Type 2" 24944010 "The influence of miRNAs (miR-7, miR-124a, miR-9, miR-96, miR-15a/b, miR-34a, miR-195, miR-376, miR-103, miR-107, and miR-146) in insulin secretion and beta (β) cell development has been well discussed." other hsa-mir-383 "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-384 "Diabetes Mellitus, Type 2" 24944010 "Here, we highlight the role of miRNAs in different significant protein cascades within the insulin signaling pathway such as miR-320, miR-383, miR-181b with IGF-1, and its receptor (IGF1R); miR-128a, miR-96, miR-126 with insulin receptor substrate (IRS) proteins; miR-29, miR-384-5p, miR-1 with phosphatidylinositol 3-kinase (PI3K); miR-143, miR-145, miR-29, miR-383, miR-33a/b miR-21 with AKT/protein kinase B (PKB) and miR-133a/b, miR-223, miR-143 with glucose transporter 4 (GLUT4)." other hsa-mir-7 "Diabetes Mellitus, Type 2" 24944010 "The influence of miRNAs (miR-7, miR-124a, miR-9, miR-96, miR-15a/b, miR-34a, miR-195, miR-376, miR-103, miR-107, and miR-146) in insulin secretion and beta (β) cell development has been well discussed." other hsa-mir-9 "Diabetes Mellitus, Type 2" 24944010 "The influence of miRNAs (miR-7, miR-124a, miR-9, miR-96, miR-15a/b, miR-34a, miR-195, miR-376, miR-103, miR-107, and miR-146) in insulin secretion and beta (β) cell development has been well discussed." other hsa-mir-96 "Diabetes Mellitus, Type 2" 24944010 "The influence of miRNAs (miR-7, miR-124a, miR-9, miR-96, miR-15a/b, miR-34a, miR-195, miR-376, miR-103, miR-107, and miR-146) in insulin secretion and beta (β) cell development has been well discussed." other hsa-mir-146b "Carcinoma, Thyroid" 24946010 The roles of the epithelial-mesenchymal transition marker PRRX1 and miR-146b-5p in papillary thyroid carcinoma progression. other hsa-mir-29c Bladder Neoplasms 24952510 Down-regulation of miR-29c in human bladder cancer and the inhibition of proliferation in T24 cell via PI3K-AKT pathway. other hsa-mir-33 Atherosclerosis 24953492 "Taken together, these results reveal that C. pneumoniae may negatively regulate ABCA1 expression via TLR2-NF-¦ÊB and miR-33 pathways in THP-1 macrophage-derived foam cells, which may provide new insights for understandingthe effects of C. pneumoniae on the pathogenesis of atherosclerosis." other hsa-mir-29c Influenza 24953694 Induction of the cellular miR-29c by influenza virus inhibits the innate immune response through protection of A20 mRNA. other hsa-mir-130a "Carcinoma, Gallbladder" 24953832 "Together, these results suggest that HOTAIR is a c-Myc-activated driver of malignancy, which acts in part through repression of miRNA-130a." other hsa-mir-124 Glioblastoma 24954504 MicroRNA-124 expression counteracts pro-survival stress responses in glioblastoma. other hsa-mir-222 "Carcinoma, Lung, Non-Small-Cell" 24955421 MicroRNA-222 expression and its prognostic potential in non-small cell lung cancer. other hsa-mir-199a Osteosarcoma 24957404 MicroRNA-199a-3p and microRNA-34a regulate apoptosis in human osteosarcoma cells. other hsa-mir-34a Osteosarcoma 24957404 MicroRNA-199a-3p and microRNA-34a regulate apoptosis in human osteosarcoma cells. other hsa-mir-101 Lung Neoplasms 24958470 IL-1¦Â-mediated repression of microRNA-101 is crucial for inflammation-promoted lung tumorigenesis. other hsa-mir-126 Chronic Heart Failure 24958738 "In conclusion, the present study shows that HDL isolated from CHF patients (NYHA-III) reduces the expression of pro-angiogenic miRs (i.e. miR-126 and miR-21), which may contribute to atherogenesis and endothelial dysfunction. However, exercise training was able to attenuate the HDL-induced reduction in pro-angiogenic miRs expression." other hsa-mir-21 Chronic Heart Failure 24958738 "In conclusion, the present study shows that HDL isolated from CHF patients (NYHA-III) reduces the expression of pro-angiogenic miRs (i.e. miR-126 and miR-21), which may contribute to atherogenesis and endothelial dysfunction. However, exercise training was able to attenuate the HDL-induced reduction in pro-angiogenic miRs expression." other hsa-mir-214 Chronic Heart Failure 24958738 "In conclusion, the present study shows that HDL isolated from CHF patients (NYHA-III) reduces the expression of pro-angiogenic miRs (i.e. miR-126 and miR-21), which may contribute to atherogenesis and endothelial dysfunction. However, exercise training was able to attenuate the HDL-induced reduction in pro-angiogenic miRs expression." other hsa-mir-221 Chronic Heart Failure 24958738 "In conclusion, the present study shows that HDL isolated from CHF patients (NYHA-III) reduces the expression of pro-angiogenic miRs (i.e. miR-126 and miR-21), which may contribute to atherogenesis and endothelial dysfunction. However, exercise training was able to attenuate the HDL-induced reduction in pro-angiogenic miRs expression." other hsa-mir-222 Chronic Heart Failure 24958738 "In conclusion, the present study shows that HDL isolated from CHF patients (NYHA-III) reduces the expression of pro-angiogenic miRs (i.e. miR-126 and miR-21), which may contribute to atherogenesis and endothelial dysfunction. However, exercise training was able to attenuate the HDL-induced reduction in pro-angiogenic miRs expression." other hsa-mir-21 Human Immunodeficiency Virus Infection 24961346 Relevance of miR-21 in HIV and non-HIV-related lymphomas. other hsa-mir-145 "Carcinoma, Gallbladder" 24966896 miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer. other hsa-mir-200 Ovarian Neoplasms 24966949 Clinicopathological and prognostic implications of the miR-200 family in patients with epithelial ovarian cancer. other hsa-mir-200 Breast Neoplasms 24967704 The tetraindole SK228 reverses the epithelial-to-mesenchymal transition of breast cancer cells by up-regulating members of the miR-200 family. other hsa-mir-424 Neoplasms [unspecific] 24967963 Hypoxia-induced miR-424 decreases tumor sensitivity to chemotherapy by inhibiting apoptosis. other hsa-mir-20a Neoplasms [unspecific] 24969314 "Furthermore, we demonstrated that upregulation of the miR-17-92 cluster (miR-20a/miR-17-5p) is involved in the regulation of E2F1-mediated negative feedback of the c-Myc/hTERT pathway." other hsa-mir-31 Medulloblastoma 24970811 MicroRNA-31 suppresses medulloblastoma cell growth by inhibiting DNA replication through minichromosome maintenance 2. other hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 24971479 Role of miR-15/16 in CLL. other hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 24971479 Role of miR-15/16 in CLL. other hsa-mir-124 Osteosarcoma 24971902 The tumor suppressor role of miR-124 in osteosarcoma. other hsa-mir-630 Prostate Neoplasms 24971999 Gefitinib and luteolin cause growth arrest of human prostate cancer PC-3 cells via inhibition of cyclin G-associated kinase and induction of miR-630. other hsa-mir-122 "Fatty Liver, Non-Alcoholic" 24973316 miR-122 plays a role of physiological significance in the biology of NAFLD; circulating miRNAs mirror the histological and molecular events occurring in the liver. NAFLD has a distinguishing circulating miRNA profile associated with a global dysmetabolic disease state and cardiovascular risk. other hsa-mir-142 Glioma 24974128 These data indicate a unique role of miR-142-3p in glioma immunity by modulating M2 macrophages through the transforming growth factor beta signaling pathway. other hsa-mir-18a "Carcinoma, Hepatocellular" 24975878 Elevated p53 promotes the processing of miR-18a to decrease estrogen receptor-¦Á in female hepatocellular carcinoma. other hsa-mir-483 Vascular Disease [unspecific] 24976017 Angiotensin II-regulated microRNA 483-3p directly targets multiple components of the renin-angiotensin system. other hsa-mir-31 Lung Neoplasms 24978700 Allelic imbalance in the miR-31 host gene locus in lung cancer--its potential role in carcinogenesis. other hsa-mir-21 Breast Malignant Phyllodes Tumor 24980553 miR-21 induces myofibroblast differentiation and promotes the malignant progression of breast phyllodes tumors. other hsa-mir-21 Multiple Myeloma 24981236 MicroRNA-21 and multiple myeloma: small molecule and big function. other hsa-mir-630 Colorectal Carcinoma 24981248 MicroRNA-630 is a prognostic marker for patients with colorectal cancer. other hsa-mir-34a Gastric Neoplasms 24981249 MiRNA-34a inhibits EGFR-signaling-dependent MMP7 activation in gastric cancer. other hsa-mir-29a "Tuberculosis, Pulmonary" 24981709 Dynamics of T-cell IFN-¦Ã and miR-29a expression during active pulmonary tuberculosis. other hsa-mir-1 Prostate Neoplasms 24982356 Heat-shock protein HSPB1 attenuates microRNA miR-1 expression thereby restoring oncogenic pathways in prostate cancer cells. other hsa-mir-23b Breast Neoplasms 24985346 Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells. other hsa-mir-34a Gastric Neoplasms 24988056 Luteolin Induces Apoptosis by Up-regulating miR-34a in Human Gastric Cancer Cells. other hsa-mir-17 Synovial Sarcoma 24989082 SS18-SSX-regulated miR-17 promotes tumor growth of synovial sarcoma by inhibiting p21WAF1/CIP1. other hsa-mir-155 "Lymphoma, Large B-Cell, Diffuse" 24989312 Role of miR-155 in pathogenesis of diffuse large B cell lymphoma and its possible mechanism other hsa-mir-603 Glioblastoma 24994119 A genome-wide miRNA screen revealed miR-603 as a MGMT-regulating miRNA in glioblastomas. other hsa-mir-146a Keratitis 24996260 Our data demonstrate that miR-146a controls nuclear factor kappa B-dependent inflammatory responses in keratinocytes and chronic skin inflammation in AD. other hsa-mir-125b Alzheimer Disease 25001178 MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease. other hsa-mir-17 Breast Neoplasms 25001613 Systematic analysis of metastasis-associated genes identifies miR-17-5p as a metastatic suppressor of basal-like breast cancer. other hsa-mir-203 Prostate Neoplasms 25004126 Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance. other hsa-mir-125b Acute Lung Injury 25004393 Enforced expression of miR-125b attenuates LPS-induced acute lung injury. other hsa-mir-152 Prostate Neoplasms 25004396 MicroRNA profiling of novel African American and Caucasian Prostate Cancer cell lines reveals a reciprocal regulatory relationship of miR-152 and DNA methyltranferase 1. other hsa-mir-29b Hematologic Neoplasms 25004911 Recent research of miR-29 family in hematological malignancies has proven its oncogenic as well as tumor suppressive potential. other hsa-mir-125b "Leukemia, Myeloid" 25006123 Dual mechanisms by which miR-125b represses IRF4 to induce myeloid and B-cell leukemias. other hsa-mir-451 Pulmonary Hypertension 25006399 "In conclusion, transient inhibition of miR-451 attenuated the development of PAH in hypoxia-exposed rats." other hsa-mir-204 Pulmonary Hypertension 25006436 "Novel research shows that miR-204, a microRNA recently found to be notably downregulated through induction of PARP-1 (poly [ADP-ribose] polymerase 1) by excessive DNA damage in PAH, inhibits activation of STAT3." other hsa-mir-221 Breast Neoplasms 25007959 Exosomal miR-221/222 enhances tamoxifen resistance in recipient ER-positive breast cancer cells. other hsa-mir-222 Breast Neoplasms 25007959 Exosomal miR-221/222 enhances tamoxifen resistance in recipient ER-positive breast cancer cells. other hsa-mir-17 "Carcinoma, Renal Cell" 25011053 miR-17 inhibition enhances the formation of kidney cancer spheres with stem cell/tumor initiating cell properties. other hsa-mir-101 Osteosarcoma 25013866 miR-101 blocks autophagy during the chemotherapy in osteosarcoma cells and enhances chemosensitivity in vitro. other hsa-mir-34a Ewing Sarcoma 25015333 "By demonstrating its relationship with clinical outcome, we propose evaluation of miR-34a at diagnosis of EWS patients to allow early risk stratification. Validation of these results would nonetheless ultimately need a prospective assessment." other hsa-mir-29a Osteosarcoma 25015394 Prognostic value of the microRNA-29 family in patients with primary osteosarcomas. other hsa-mir-29b Osteosarcoma 25015394 Prognostic value of the microRNA-29 family in patients with primary osteosarcomas. other hsa-mir-29c Osteosarcoma 25015394 Prognostic value of the microRNA-29 family in patients with primary osteosarcomas. other hsa-mir-142 Liver Neoplasms 25015418 Regulatory role of miR-142-3p on the functional hepatic cancer stem cell marker CD133. other hsa-mir-210 Myocardial Infarction 25016614 "MicroRNAs most highly enriched in EVs secreted by CPCs compared with fibroblasts included miR-210, miR-132, and miR-146a-3p." other hsa-mir-1290 "Carcinoma, Lung, Non-Small-Cell" 25016979 miR-1290 suppresses cell viability and cell cycle progression. These data provide insight into miR-1290-mediated cellular mechanisms in asiatic acid-treated A549 non-small cell lung carcinoma cells. other hsa-mir-9 Breast Neoplasms 25017439 FOXO1 3'UTR functions as a ceRNA in repressing the metastases of breast cancer cells via regulating miRNA activity. other hsa-mir-128 Glioblastoma 25017996 miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeletal remodeling in glioblastoma. other hsa-mir-149 Glioblastoma 25017996 miR-128 and miR-149 enhance the chemosensitivity of temozolomide by Rap1B-mediated cytoskeletal remodeling in glioblastoma. other hsa-mir-122 "Carcinoma, Hepatocellular" 25023326 Baculovirus-mediated miRNA regulation to suppress hepatocellular carcinoma tumorigenicity and metastasis. other hsa-mir-451 "Adenocarcinoma, Lung" 25026294 Acquisition of radioresistance in docetaxel-resistant human lung adenocarcinoma cells is linked with dysregulation of miR-451/c-Myc-survivin/rad-51 signaling. other hsa-mir-302c "Carcinoma, Hepatocellular" 25027009 MiR-302c inhibits tumor growth of hepatocellular carcinoma by suppressing the endothelial-mesenchymal transition of endothelial cells. other hsa-let-7 Epstein-Barr Virus Infection 25031339 Epstein-Barr virus EBNA1 protein regulates viral latency through effects on let-7 microRNA and dicer. other hsa-mir-193b "Carcinoma, Hepatocellular" 25034398 Modulation of miRNAs expression might be a potential way to enhance response to sorafenib in HBV-associated HCC. other hsa-mir-223 Gastric Neoplasms 25036956 Increased microRNA-223 in Helicobacter pylori-associated gastric cancer contributed to cancer cell proliferation and migration. other hsa-mir-122 Liver Injury 25039534 "In mice and humans, miR-122 levels represent an independent and potent marker of ongoing liver injury and hepatic cell death regardless of the underlying disease." other hsa-mir-340 Melanoma 25043973 MicroRNA-340 as a modulator of RAS-RAF-MAPK signaling in melanoma. other hsa-mir-99a "Carcinoma, Lung, Non-Small-Cell" 25046358 A novel small-molecule compound diaporine A inhibits non-small cell lung cancer growth by regulating miR-99a/mTOR signaling. other hsa-mir-941 "Carcinoma, Hepatocellular" 25049231 miR-941 and KDM6B regulated the epithelial-mesenchymal transition process and affected cell migratory/invasive properties. other hsa-mir-21 Neoplasms [unspecific] 25049417 "PAPD5 and PARN mediate degradation of oncogenic miRNA miR-21 through a tailing and trimming process, and that this pathway is disrupted in cancer and other proliferative diseases." other hsa-mir-133a Breast Neoplasms 25051376 both miR-148b and miR-133a have potential use as biomarkers for breast cancer detection other hsa-mir-148b Breast Neoplasms 25051376 both miR-148b and miR-133a have potential use as biomarkers for breast cancer detection other hsa-mir-34a Neoplasms [unspecific] 25052958 The well-formulated LPEI-CaPs with lc-miRNA-d have the potential to provide superior miRNA transfection efficiency and inhibition of cancer proliferation. other hsa-mir-146a Osteoarthritis 25052989 "The mechanism underlying the inhibitory effects of denbinobin involved miR-146a induction, which in turn inhibited NF-κB signaling." other hsa-mir-34a Prostate Neoplasms 25053345 "This study supports the extracellular environment as an important source of minimally invasive predictive biomarkers representing their cellular origin. Using miR-34a as example, we showed that biomarkers identified in this manner may also hold functional relevance." other hsa-mir-150 Melanoma 25054912 Role of microRNA-150 and glycoprotein nonmetastatic melanoma protein B in angiogenesis during hyperoxia-induced neonatal lung injury. other hsa-mir-200c Glioblastoma 25058589 Correlation between EGFR amplification and the expression of microRNA-200c in primary glioblastoma multiforme. other hsa-mir-101 Breast Neoplasms 25059472 miR-101 promotes breast cancer cell apoptosis by targeting Janus kinase 2. other hsa-mir-186 Diabetes Mellitus 25059983 Differentiation of human induced pluripotent stem cells into insulin-like cell clusters with miR-186 and miR-375 by using chemical transfection. other hsa-mir-375 Diabetes Mellitus 25059983 Differentiation of human induced pluripotent stem cells into insulin-like cell clusters with miR-186 and miR-375 by using chemical transfection. other hsa-mir-144 Ischemic Diseases [unspecific] 25060662 MicroRNA-144 is a circulating effector of remote ischemic preconditioning. other hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 25061297 "microRNAs miR-21, miR-221, miR-222, and miR-10 in PDCA cells, promoting an almost complete abolishment of microRNA expression. " other hsa-mir-221 "Adenocarcinoma, Pancreatic Ductal" 25061297 "microRNAs miR-21, miR-221, miR-222, and miR-10 in PDCA cells, promoting an almost complete abolishment of microRNA expression. " other hsa-mir-222 "Adenocarcinoma, Pancreatic Ductal" 25061297 "microRNAs miR-21, miR-221, miR-222, and miR-10 in PDCA cells, promoting an almost complete abolishment of microRNA expression. " other hsa-mir-148a Breast Neoplasms 25063027 our findings offer important new insights into the ability of estrogenic GPER signaling to trigger HLA-G expression through inhibiting miR-148a that supports immune evasion in breast cancer. other hsa-mir-26b Posterior Capsule Opacification 25063219 "MiRNA-26b inhibits the proliferation, migration, and epithelial-mesenchymal transition of lens epithelial cells." other hsa-mir-34c Breast Neoplasms 25064703 "Together, our results support the role of miR-34c as a tumor suppressor miRNA also in breast cancer." other hsa-mir-409 Prostate Neoplasms 25065597 Stromal fibroblast-derived miR-409 promotes epithelial-to-mesenchymal transition and prostate tumorigenesis. other hsa-mir-26 Cardiovascular Diseases [unspecific] 25066487 An emerging role for the miR-26 family in cardiovascular disease. other hsa-mir-34a Liver Cirrhosis 25068403 "This study demonstrates for the first time, that miRNA-34a mayoriginate to a large extent from the liver. Even though higher levels ofmiRNA-34a are possibly associated with better survival at long-term follow-up in cirrhotic patients with severe portal hypertension receiving TIPS, classical prognostic parameters predict the survival better." other hsa-mir-100 Urinary Bladder Cancer 25071007 microRNAs-99a/100 mediate a direct relationship between FGFR3 and FOXA1 and potentially facilitate cross talk between these pathways in UCC. other hsa-mir-99a Urinary Bladder Cancer 25071007 microRNAs-99a/100 mediate a direct relationship between FGFR3 and FOXA1 and potentially facilitate cross talk between these pathways in UCC. other hsa-mir-146a Myelodysplastic Syndromes 25071842 "miR-146a is also implicated in the pathogenesis of human myelodysplastic syndromes (MDSs) as it is located within a commonly deleted region on chromosome 5, and miR-146a-deficient mice exhibit features of an MDS-like disease." other hsa-mir-122 Breast Neoplasms 25078559 Neoadjuvant Chemotherapy in Breast Cancer Patients Induces miR-34a and miR-122 Expression. other hsa-mir-34a Breast Neoplasms 25078559 Neoadjuvant Chemotherapy in Breast Cancer Patients Induces miR-34a and miR-122 Expression. other hsa-mir-216b Breast Neoplasms 25078617 Regulation of the P2X7R by microRNA-216b in human breast cancer. other hsa-mir-146a Gastric Neoplasms 25081668 MicroRNA-146a enhances Helicobacter pylori induced cell apoptosis in human gastric cancer epithelial cells. other hsa-mir-487b Ischemic Diseases [unspecific] 25085941 The 14q32 microRNA gene cluster is highly involved in neovascularization. other hsa-mir-494 Ischemic Diseases [unspecific] 25085941 The 14q32 microRNA gene cluster is highly involved in neovascularization. other hsa-mir-495 Ischemic Diseases [unspecific] 25085941 The 14q32 microRNA gene cluster is highly involved in neovascularization. other hsa-mir-155 Breast Neoplasms 25086633 "MicroRNA-9 is associated with epithelial-mesenchymal transition, breast cancer stem cell phenotype, and tumor progression in breast cancer." other hsa-mir-200 Breast Neoplasms 25086633 "MicroRNA-9 is associated with epithelial-mesenchymal transition, breast cancer stem cell phenotype, and tumor progression in breast cancer." other hsa-mir-9 Breast Neoplasms 25086633 "MicroRNA-9 is associated with epithelial-mesenchymal transition, breast cancer stem cell phenotype, and tumor progression in breast cancer." other hsa-mir-210 Prostate Neoplasms 25091736 Senescent stroma promotes prostate cancer progression: the role of miR-210. other hsa-mir-106b Renal Fibrosis 25094038 Expression of miR-106b-25 induced by salvianolic acid B inhibits epithelial-to-mesenchymal transition in HK-2 cells. other hsa-mir-152 "Carcinoma, Laryngeal" 25095980 Expression and clinical significance of microRNA-152 in supragalottic laryngeal carcinoma. other hsa-mir-508 "Squamous Cell Carcinoma, Esophageal" 25099196 miR-508 sustains phosphoinositide signalling and promotes aggressive phenotype of oesophageal squamous cell carcinoma. other hsa-mir-146a Graves Ophthalmopathy 25100151 Circulating levels of miR-146a and IL-17 are significantly correlated with the clinical activity of Graves' ophthalmopathy. other hsa-mir-34 Neoplasms [unspecific] 25102298 Role of microRNA-34 family in cancer with particular reference to cancer angiogenesis. other hsa-mir-15 Cardiomegaly 25103110 We identified the miR-15 family as a novel regulator of cardiac hypertrophy and fibrosis acting by inhibition of the TGF¦Â-pathway. other hsa-mir-133a Colorectal Carcinoma 25104873 The clinicopathological significance of miR-133a in colorectal cancer. other hsa-mir-196a Focal Segmental Glomerulosclerosis 25107948 "The levels of urinary miR-196a, miR-30a-5p, and miR-490 are associated with FSGS disease activity." other hsa-mir-30a Focal Segmental Glomerulosclerosis 25107948 "The levels of urinary miR-196a, miR-30a-5p, and miR-490 are associated with FSGS disease activity." other hsa-mir-490 Focal Segmental Glomerulosclerosis 25107948 "The levels of urinary miR-196a, miR-30a-5p, and miR-490 are associated with FSGS disease activity." other hsa-mir-100 "Squamous Cell Carcinoma, Esophageal" 25109390 MicroRNA-100 promotes migration and invasion through mammalian target of rapamycin in esophageal squamous cell carcinoma. other hsa-mir-101 Bladder Neoplasms 25109742 Enforced expression of miR-101 enhances cisplatin sensitivity in human bladder cancer cells by modulating the cyclooxygenase-2 pathway. other hsa-mir-218 "Carcinoma, Hepatocellular" 25110121 Prognostic significance of miR-218 in human hepatocellular carcinoma and its role in cell growth. other hsa-mir-497 Acute Myocardial Infarction 25110754 High association between human circulating microRNA-497 and acute myocardial infarction. other hsa-mir-499 Myocardial Infarction 25111390 "Our results demonstrate that circulating miR-499 is a novel, early biomarker for identifying perioperative myocardial infarction in cardiac surgery." other hsa-mir-665 Heart Failure 25111814 MicroRNA-665 is involved in the regulation of the expression of the cardioprotective cannabinoid receptor CB2 in patients with severe heart failure. other hsa-mir-124 Prostate Neoplasms 25115393 The miR-124-prolyl hydroxylase P4HA1-MMP1 axis plays a critical role in prostate cancer progression. other hsa-mir-23b Prostate Neoplasms 25115396 The microRNA-23b/27b/24-1 cluster is a disease progression marker and tumor suppressor in prostate cancer. other hsa-mir-24-1 Prostate Neoplasms 25115396 The microRNA-23b/27b/24-1 cluster is a disease progression marker and tumor suppressor in prostate cancer. other hsa-mir-27b Prostate Neoplasms 25115396 The microRNA-23b/27b/24-1 cluster is a disease progression marker and tumor suppressor in prostate cancer. other hsa-mir-1291 "Carcinoma, Pancreatic" 25115443 N-methylnicotinamide and nicotinamide N-methyltransferase are associated with microRNA-1291-altered pancreatic carcinoma cell metabolome and suppressed tumorigenesis. other hsa-mir-138 Prostate Neoplasms 25116803 α-solanine downregulates oncogenic microRNA-21 (miR-21) and upregulates tumor suppressor miR-138 expression. other hsa-mir-21 Prostate Neoplasms 25116803 α-solanine downregulates oncogenic microRNA-21 (miR-21) and upregulates tumor suppressor miR-138 expression. other hsa-mir-122 "Fatty Liver, Non-Alcoholic" 25117675 Silencing of microRNA-122 is an early event during hepatocarcinogenesis from non-alcoholic steatohepatitis. other hsa-mir-218 "Carcinoma, Hepatocellular" 25120782 miR-218 modulate hepatocellular carcinoma cell proliferation through PTEN/AKT/PI3K pathway and HoxA10. other hsa-mir-30e Dengue Virus Infection 25122182 MicroRNA-30e* suppresses dengue virus replication by promoting NF-¦ÊB-dependent IFN production. other hsa-mir-181b Pancreatic Neoplasms 25126577 "Some miRNAs were found to be specifically expressed in some ZHENGs, for instance, miR-17, miR-21, and miR-181b in Shi-Re ZHENG and miR-196a in Pi-Xu ZHENG." other hsa-mir-1290 Prostate Neoplasms 25129854 Exosomal miR-1290 and miR-375 as prognostic markers in castration-resistant prostate cancer. other hsa-mir-375 Prostate Neoplasms 25129854 Exosomal miR-1290 and miR-375 as prognostic markers in castration-resistant prostate cancer. other hsa-mir-17 Leukemia 25130806 Anti-leukemia mechanism of miR-17 and miR-20a silencing mediated by miRNA sponge. other hsa-mir-20a Leukemia 25130806 Anti-leukemia mechanism of miR-17 and miR-20a silencing mediated by miRNA sponge. other hsa-mir-192 Cholangiocarcinoma 25131257 This finding indicates that elevated levels of miR-192 may be involved in CCA genesis and have a potential utility as a noninvasive prognostic indicator for CCA patients. other hsa-mir-541 Prostate Neoplasms 25135278 Infiltrating T cells promote prostate cancer metastasis via modulation of FGF11¡úmiRNA-541¡úandrogen receptor (AR)¡úMMP9 signaling. other hsa-mir-31 Neoplasms [unspecific] 25139099 Prognostic role of microRNA-31 in various cancers: a meta-analysis. other hsa-mir-24 Osteosarcoma 25142229 Nucleotidyl transferase TUT1 inhibits lipogenesis in osteosarcoma cells through regulation of microRNA-24 and microRNA-29a. other hsa-mir-29a Osteosarcoma 25142229 Nucleotidyl transferase TUT1 inhibits lipogenesis in osteosarcoma cells through regulation of microRNA-24 and microRNA-29a. other hsa-mir-29a Cardiomegaly 25145535 MicroRNA-29a is a friend or foe for cardiac hypertrophy other hsa-mir-618 Thyroid Neoplasms 25145559 MiR-618 inhibits anaplastic thyroid cancer by repressing XIAP in one ATC cell line. other hsa-mir-21 Kidney Injury 25145934 MicroRNA-21 in glomerular injury. other hsa-mir-15 Salmonellosis 25146723 Functional high-throughput screening identifies the miR-15 microRNA family as cellular restriction factors for Salmonella infection. other hsa-mir-133a Muscle Diseases [unspecific] 25146754 These miRNAs are potential biomarkers of muscle damage or adaptation to exercise. other hsa-mir-206 Muscle Diseases [unspecific] 25146754 These miRNAs are potential biomarkers of muscle damage or adaptation to exercise. other hsa-mir-21 Neoplasms [unspecific] 25149066 miR-21-3p is a positive regulator of L1CAM in several human carcinomas. other hsa-mir-7 Glioblastoma 25149532 Systemic miRNA-7 delivery inhibits tumor angiogenesis and growth in murine xenograft glioblastoma. other hsa-mir-30a Neuroblastoma 25149854 Lithium/Valproic acid combination and L-glutamate induce similar pattern of changes in the expression of miR-30a-5p in SH-SY5Y neuroblastoma cells. other hsa-mir-122 Breast Neoplasms 25150312 Breast cancer-specific TRAIL expression mediated by miRNA response elements of let-7 and miR-122. other hsa-mir-451 Lung Neoplasms 25150396 MiR-451 suppresses cell proliferation and metastasis in A549 lung cancer cells. other hsa-mir-130b Ovarian Neoplasms 25155039 MicroRNA 130b enhances drug resistance in human ovarian cancer cells. other hsa-mir-125b "Carcinoma, Renal Cell, Clear-Cell" 25155155 Tumor miR-125b predicts recurrence and survival of patients with clear-cell renal cell carcinoma after surgical resection. other hsa-mir-378 Aortic Stenosis 25157568 "Circulating levels of miR-1, miR-133 and miR-378 were decreased in AS patients, and miR-378 predicts LVH independent of the pressure gradient. Further prospective investigations are needed to elucidate whether these circulating miRs affect clinical outcome." other hsa-mir-21 Ischemia-Reperfusion Injury 25159851 miR-21 in ischemia/reperfusion injury: a double-edged sword other hsa-mir-106b Bladder Neoplasms 25168920 Urinary cell-free microRNA-106b as a novel biomarker for detection of bladder cancer. other hsa-mir-520h Neoplasms [unspecific] 25169894 "PD-miRNAs that are currently implicated as cancer biomarkers or diagnostics: hsa-mir-202, hsa-mir-423, hsa-mir-196a-2, hsa-mir-520h, hsa-mir-647, hsa-mir-943, and hsa-mir-1908." other hsa-mir-29 Breast Neoplasms 25174825 Aberrant miR-29 expression may account for reduced NMI expression in breast tumors and mesenchymal phenotype of cancer cells that promotes invasive growth. Reduction in NMI levels has a feed-forward impact on miR-29 levels. other hsa-mir-29b-1 Osteosarcoma 25174983 "MicroRNA-29b-1 impairs in vitro cell proliferation, self-renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells." other hsa-mir-124a Glioma 25175832 miR-124a restoration inhibits glioma cell proliferation and invasion by suppressing IQGAP1 and ¦Â-catenin. other hsa-mir-21 "Squamous Cell Carcinoma, Head and Neck" 25175929 miR-21 increases the programmed cell death 4 gene-regulated cell proliferation in head and neck squamous carcinoma cell lines. other hsa-mir-1 Heart Diseases [unspecific] 25177824 miRNA-1: functional roles and dysregulation in heart disease. other hsa-mir-21 Colorectal Carcinoma 25178983 "Circulating miR21 level has potential value for colorectal cancer early detection, whereas high tissue miR21 level is associated with adverse colorectal cancer prognosis." other hsa-mir-152 "Carcinoma, Lung, Non-Small-Cell" 25190353 MiR-152 suppresses the proliferation and invasion of NSCLC cells by inhibiting FGF2. other hsa-mir-122 "Carcinoma, Ovarian" 25195148 A polymorphism at miRNA-122-binding site in the IL-1¦Á 3'UTR is associated with risk of epithelial ovarian cancer. other hsa-mir-375 Neoplasms [unspecific] 25195536 "The CMAP database is a useful tool for identifying compounds affecting the same molecular pathways, particularly products that are difficult to apply via practical approaches, such as microRNAs." other hsa-mir-1280 Melanoma 25195599 Antitumor activity of miR-1280 in melanoma by regulation of Src. other hsa-mir-1 Colorectal Carcinoma 25196260 Tumor suppressor miR-1 restrains epithelial-mesenchymal transition and metastasis of colorectal carcinoma via the MAPK and PI3K/AKT pathway. other hsa-mir-107 Colorectal Carcinoma 25197016 MiR-107 and miR-99a-3p were validated as predictors of response to standard fluoropyrimidine-based chemotherapy in patients with mCRC. other hsa-mir-99a Colorectal Carcinoma 25197016 MiR-107 and miR-99a-3p were validated as predictors of response to standard fluoropyrimidine-based chemotherapy in patients with mCRC. other hsa-mir-126 "Carcinoma, Colon" 25199818 The current population based study of patients operated for stage II colon cancer demonstrated correlations between several prognostic unfavourable characteristics and miRNA-126 and argues for a possible prognostic impact on overall survival. An influence on survival by the MVD estimate was not detected. other hsa-mir-195 Aortic Aneurysm 25201911 "We provide the first evidence that miR-195 may contribute to the pathogenesis of aortic aneurysmal disease. Although inhibition of miR-29b proved more effective in preventing aneurysm formation in a preclinical model, miR-195represents a potent regulator of the aortic extracellular matrix. Notably, plasma levels of miR-195 were reduced in patients with abdominal aortic aneurysms suggesting that microRNAs might serve as a noninvasive biomarker of abdominal aortic aneurysms." other hsa-mir-33a Glioma 25202981 miR-33a promotes glioma-initiating cell self-renewal via PKA and NOTCH pathways. other hsa-mir-200a Liver Neoplasms 25203708 MiR-200a may play an important role in liver cancer development and may have diagnostic value for indicating early liver cancer. other hsa-mir-21 Periodontal Diseases 25203845 microRNA-21 mediates stretch-induced osteogenic differentiation in human periodontal ligament stem cells. other hsa-let-7d Glioblastoma 25212824 the current study is the first to demonstrate the effect of FCL on modulation of let-7d expression other hsa-mir-193b Breast Neoplasms 25213330 Metformin-induced killing of triple-negative breast cancer cells is mediated by reduction in fatty acid synthase via miRNA-193b. other hsa-mir-25 Heart Failure 25214573 miR-25 in heart failure. other hsa-mir-185 "Carcinoma, Colon" 25216407 MicroRNA-185 suppresses growth and invasion of colon cancer cells through inhibition of the hypoxia-inducible factor-2¦Á pathway in vitro and in vivo. other hsa-mir-199 Cholangiocarcinoma 25217977 the cell proliferation and inhibition of tumor suppression mediated by these miRNAs is common to both cancerous and non-cancerous cells. other hsa-mir-22 Cardiovascular Diseases [unspecific] 25218673 miR-22 in cardiac remodeling and disease. other hsa-mir-1246 Ebola Hemorrhagic Fever 25218824 "Hsa-miR-1246, hsa-miR-320a and hsa-miR-196b-5p inhibitors can reduce the cytotoxicity of Ebola virus glycoprotein in vitro." other hsa-mir-133b Parkinson Disease 25218846 Our observations suggest that miR-133b might be involved in ceruloplasmin dysmetabolism in PD patients and a further investigation is warranted to confirm this hypothesis. other hsa-mir-34a Neoplasms [unspecific] 25220161 Dual drugs (microRNA-34a and paclitaxel)-loaded functional solid lipid nanoparticles for synergistic cancer cell suppression. other hsa-mir-214 Neoplasms [unspecific] 25223704 Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth. other hsa-mir-494 Lung Neoplasms 25226615 Overexpression of secretagogin inhibits cell apoptosis and induces chemoresistance in small cell lung cancer under the regulation of miR-494. other hsa-mir-143 Osteosarcoma 25227664 MiR-143 inhibits EGFR-signaling-dependent osteosarcoma invasion. other hsa-mir-34b Neoplasms [unspecific] 25227823 Association between a polymorphism in miR-34b/c and susceptibility to cancer--a meta-analysis. other hsa-mir-34c Neoplasms [unspecific] 25227823 Association between a polymorphism in miR-34b/c and susceptibility to cancer--a meta-analysis. other hsa-mir-155 Lung Neoplasms 25230125 Chitosan combined with molecular beacon for mir-155 detection and imaging in lung cancer. other hsa-mir-34a "Carcinoma, Nasopharyngeal" 25231528 Hypofractionated radiotherapy induces miR-34a expression and enhances apoptosis in human nasopharyngeal carcinoma cells. other hsa-mir-137 Glioblastoma 25232498 "OLE significantly induced the expression of miR-153, miR-145, and miR-137 and decreased the expression of the target genes of these miRNAs in GSCs" other hsa-mir-145 Glioblastoma 25232498 "OLE significantly induced the expression of miR-153, miR-145, and miR-137 and decreased the expression of the target genes of these miRNAs in GSCs" other hsa-mir-18a Colorectal Carcinoma 25233396 Stool-based miR-221 can be used as a non-invasive biomarker for the detection of CRC. other hsa-mir-221 Colorectal Carcinoma 25233396 Stool-based miR-221 can be used as a non-invasive biomarker for the detection of CRC. other hsa-mir-217 Lung Neoplasms 25234467 MicroRNA-217 functions as a tumour suppressor gene and correlates with cell resistance to cisplatin in lung cancer. other hsa-mir-21 "Squamous Cell Carcinoma, Oral" 25236707 Human papillomavirus-stratified analysis of the prognostic role of miR-21 in oral cavity and oropharyngeal squamous cell carcinoma. other hsa-mir-451a Melanoma 25237911 "A novel miR-451a isomiR, associated with amelanotypic phenotype, acts as a tumor suppressor in melanoma by retarding cell migration and invasion." other hsa-mir-93 Breast Neoplasms 25238878 Identification of microRNA-93 as a functional dysregulated miRNA in triple-negative breast cancer. other hsa-mir-92a Acute Myocardial Infarction 25240056 Early single intracoronary administration of encapsulated antagomir-92a in an adult pig model of reperfused AMI prevents left ventricular remodeling with no local or distant adverse effects other hsa-mir-16 Glioma 25242314 MicroRNA-16 suppresses epithelial-mesenchymal transition-related gene expression in human glioma. other hsa-mir-5481 Lung Neoplasms 25245053 These results suggested that miR-548l may play a causal role through AKT1 in NSCLC invasion and metastasis. other hsa-mir-17 Diabetes Mellitus 25249581 "Ask1 deletion suppressed diabetes-induced IRE1α endoriboneclease activities, which led to X-box binding protein 1 mRNA cleavage, an ER stress marker, decreased expression of microRNAs, and increased expression of a miR-17 target" other hsa-mir-137 Schizophrenia 25250332 Association of a miRNA-137 polymorphism with schizophrenia in a Southern Chinese Han population. other hsa-mir-141 "Adenocarcinoma, Prostate" 25252191 "Based on this small pilot study, men with localized prostate cancers with lower miR-221 expression may have a greater risk for recurrence after surgery." other hsa-mir-21 "Adenocarcinoma, Prostate" 25252191 "Based on this small pilot study, men with localized prostate cancers with lower miR-221 expression may have a greater risk for recurrence after surgery." other hsa-mir-221 "Adenocarcinoma, Prostate" 25252191 "Based on this small pilot study, men with localized prostate cancers with lower miR-221 expression may have a greater risk for recurrence after surgery." other hsa-mir-191 Lung Neoplasms 25252218 "MicroRNA-191, by promoting the EMT and increasing CSC-like properties, is involved in neoplastic and metastatic properties of transformed human bronchial epithelial cells." other hsa-mir-132 Mycobacterium tuberculosis Infection 25252958 Mycobacterium tuberculosis decreases human macrophage IFN-¦Ã responsiveness through miR-132 and miR-26a. other hsa-mir-26a Mycobacterium tuberculosis Infection 25252958 Mycobacterium tuberculosis decreases human macrophage IFN-¦Ã responsiveness through miR-132 and miR-26a. other hsa-mir-96 Colorectal Carcinoma 25256312 MiR-96-5p influences cellular growth and is associated with poor survival in colorectal cancer patients. other hsa-mir-148 Gastric Neoplasms 25261463 Polymorphisms and haplotypes of the miR-148/152 family are associated with the risk and clinicopathological features of gastric cancer in a Northern Chinese population. other hsa-mir-152 Gastric Neoplasms 25261463 Polymorphisms and haplotypes of the miR-148/152 family are associated with the risk and clinicopathological features of gastric cancer in a Northern Chinese population. other hsa-mir-210 "Adenocarcinoma, Lung" 25263437 Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of miR-210 in lung adenocarcinoma cells and their exosomes. other hsa-mir-122 Viral Infectious Disease 25265013 MiR-122 directly inhibits human papillomavirus E6 gene and enhances interferon signaling through blocking suppressor of cytokine signaling 1 in SiHa cells. other hsa-mir-148b Asthma 25266681 "We report that statins upregulate mir-148b and 152, and affect HLA-G expression in an rs1063320-dependent fashion." other hsa-mir-152 Asthma 25266681 "We report that statins upregulate mir-148b and 152, and affect HLA-G expression in an rs1063320-dependent fashion." other hsa-mir-21 Bladder Neoplasms 25266796 A lentiviral sponge for miRNA-21 diminishes aerobic glycolysis in bladder cancer T24 cells via the PTEN/PI3K/AKT/mTOR axis. other hsa-mir-122 "Carcinoma, Hepatocellular" 25269820 MicroRNA sponge blocks the tumor-suppressing functions of microRNA-122 in human hepatoma and osteosarcoma cells. other hsa-mir-122 Osteosarcoma 25269820 MicroRNA sponge blocks the tumor-suppressing functions of microRNA-122 in human hepatoma and osteosarcoma cells. other hsa-mir-200 Gastric Neoplasms 25270520 MicroRNA-200 family members and ZEB2 are associated with brain metastasis in gastric adenocarcinoma. other hsa-mir-34c Ovarian Neoplasms 25273528 Functional analysis of miR-34c as a putative tumor suppressor in high-grade serous ovarian cancer. other hsa-mir-122 Hepatitis C Virus Infection 25275643 "Exosome-loading with a miR-122 inhibitor, or inhibition of HSP90, vacuolar H+-ATPases, and proton pumps, significantly suppressed exosome-mediated HCV transmission to naïve cells." other hsa-mir-126 "Carcinoma, Renal Cell" 25279769 "Impact of miR-21, miR-126 and miR-221 as prognostic factors of clear cell renal cell carcinoma with tumor thrombus of the inferior vena cava." other hsa-mir-21 "Carcinoma, Renal Cell" 25279769 "Impact of miR-21, miR-126 and miR-221 as prognostic factors of clear cell renal cell carcinoma with tumor thrombus of the inferior vena cava." other hsa-mir-221 "Carcinoma, Renal Cell" 25279769 "Impact of miR-21, miR-126 and miR-221 as prognostic factors of clear cell renal cell carcinoma with tumor thrombus of the inferior vena cava." other hsa-mir-105 "Carcinoma, Hepatocellular" 25280563 MicroRNA-105 suppresses cell proliferation and inhibits PI3K/AKT signaling in human hepatocellular carcinoma. other hsa-mir-155 Prostate Neoplasms 25283513 Inhibition of transforming growth factor beta/SMAD signal by MiR-155 is involved in arsenic trioxide-induced anti-angiogenesis in prostate cancer. other hsa-mir-3127 "Carcinoma, Lung, Non-Small-Cell" 25284075 Reduced miR-3127-5p expression promotes NSCLC proliferation/invasion and contributes to dasatinib sensitivity via the c-Abl/Ras/ERK pathway. other hsa-mir-203 Squamous Cell Carcinoma 25284788 "Rewiring of an epithelial differentiation factor, miR-203, to inhibit human squamous cell carcinoma metastasis." other hsa-mir-106b Neoplasms [unspecific] 25286029 miR-106b modulates cancer stem cell characteristics through TGF-¦Â/Smad signaling in CD44-positive gastric cancer cells. other hsa-mir-495 "Carcinoma, Lung" 25286762 MicroRNA-495 mimics delivery inhibits lung tumor progression. other hsa-mir-720 Lung Neoplasms 25286763 Evaluation of miR-720 prognostic significance in patients with colorectal cancer. other hsa-mir-139 Colorectal Carcinoma 25286864 Gene module based regulator inference identifying miR-139 as a tumor suppressor in colorectal cancer. other hsa-mir-7 "Carcinoma, Lung, Non-Small-Cell" 25289099 Upregulation of miR-7 enhanced the PTX-sensitivity of NSCLC cells by suppressing cell proliferation and promoting cell apoptosis other hsa-mir-142 "Carcinoma, Hepatocellular" 25292173 This study reveals a novel role for propofol in the inhibition of HCC through MV-mediated transfer of miR-142-3p from macrophages to cancer cells in vivo. other hsa-mir-204 Colorectal Carcinoma 25294901 Our results demonstrate for the first time that miR-204-5p acts as a tumor suppressor in colorectal cancer through inhibiting RAB22A and reveal RAB22A to be a new oncogene and prognostic factor for colorectal cancer. other hsa-mir-490 Ovarian Neoplasms 25297343 microRNA 490-3P enhances the drug-resistance of human ovarian cancer cells. other hsa-mir-212 "Carcinoma, Esophageal" 25299094 Overregulation of microRNA-212 in the poor prognosis of esophageal cancer patients. other hsa-mir-122 Hepatitis B Virus Infection 25299106 Expression and clinical significance of miR-122 and miR-29 in hepatitis B virus-related liver disease. other hsa-mir-29 Hepatitis B Virus Infection 25299106 Expression and clinical significance of miR-122 and miR-29 in hepatitis B virus-related liver disease. other hsa-mir-491 "Carcinoma, Ovarian" 25299770 miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation. other hsa-mir-126 Inflammation 25300227 Polyphenolic extracts from cowpea (Vigna unguiculata) protect colonic myofibroblasts (CCD18Co cells) from lipopolysaccharide (LPS)-induced inflammation--modulation of microRNA 126. other hsa-mir-30b Heart Failure 25301066 E2F1 transcriptionally represses miR-30b expression. other hsa-mir-106a Helicobacter pylori Infection 25307786 A MDM2-dependent positive-feedback loop is involved in inhibition of miR-375 and miR-106b induced by Helicobacter pylori lipopolysaccharide. other hsa-mir-375 Helicobacter pylori Infection 25307786 A MDM2-dependent positive-feedback loop is involved in inhibition of miR-375 and miR-106b induced by Helicobacter pylori lipopolysaccharide. other hsa-mir-29a Vascular Hypertrophy 25308856 Effect of miR-29a inhibition on ventricular hypertrophy induced by pressure overload. other hsa-mir-429 "Carcinoma, Hepatocellular, HBV-Related" 25312821 miR-429 represses cell proliferation and induces apoptosis in HBV-related HCC. other hsa-mir-133a Cardiomegaly 25313674 Our observations supplied the possibility that circulating miR-133a could be a surrogate biomarker of cardiac hypertrophy in MHD patients. other hsa-mir-126 Atherosclerosis 25315114 "MicroRNAs (miRNAs) encapsulated within microparticles (MPs) are likely to have a role in cell-to-cell signaling in a variety of diseases, including atherosclerosis." other hsa-mir-21 "Carcinoma, Thyroid" 25316501 The PDCD4/miR-21 pathway in medullary thyroid carcinoma. other hsa-mir-125b-1 "Leukemia, Myeloid" 25316507 "Myeloid neoplasm with translocation t(2;11)(p21;q23-24), elevated microRNA 125b-1, and JAK2 exon 12 mutation." other hsa-mir-135a Gastric Neoplasms 25322930 Regulation of BGC-823 cell sensitivity to adriamycin via miRNA-135a-5p. other hsa-mir-21 Lung Neoplasms 25323306 Effect of microRNA-21 on multidrug resistance reversal in A549/DDP human lung cancer cells. other hsa-mir-146a Glioblastoma 25326894 The Downregulation of MicroRNA-146a Modulates TGF-¦Â Signaling Pathways Activityin Glioblastoma. other hsa-mir-106b "Carcinoma, Hepatocellular" 25327652 Effects of miR-106b expression on the proliferation of human hepatocellular carcinoma cells. other hsa-mir-200a Ovarian Neoplasms 25327865 Involvement of miR-200a in chemosensitivity regulation of ovarian cancer. other hsa-mir-378 Colorectal Carcinoma 25328987 MicroRNA-378 inhibits cell growth and enhances L-OHP-induced apoptosis in human colorectal cancer. other hsa-mir-33a Inflammation 25329888 Effects of miR-33a-5P on ABCA1/G1-mediated cholesterol efflux under inflammatory stress in THP-1 macrophages. other hsa-mir-375 "Carcinoma, Cervical" 25330011 miR-375 mediated acquired chemo-resistance in cervical cancer by facilitating EMT. other hsa-let-7a Colon Neoplasms 25330373 "63 miRNA are selectively enriched in the EVs--miR-19a/b-3p, miR-378a/c/d, and miR-577 and members of the let-7 and miR-8 families being the most prominent." other hsa-let-7f Colon Neoplasms 25330373 "63 miRNA are selectively enriched in the EVs--miR-19a/b-3p, miR-378a/c/d, and miR-577 and members of the let-7 and miR-8 families being the most prominent." other hsa-mir-96 Prostate Neoplasms 25333253 Biphasic regulation of autophagy by miR-96 in prostate cancer cells under hypoxia. other hsa-mir-573 Breast Neoplasms 25333258 MiR-578 and miR-573 as potential players in BRCA-related breast cancer angiogenesis. other hsa-mir-578 Breast Neoplasms 25333258 MiR-578 and miR-573 as potential players in BRCA-related breast cancer angiogenesis. other hsa-mir-34a "Carcinoma, Colon" 25333573 Inhibition of lactate dehydrogenase A by microRNA-34a resensitizes colon cancer cells to 5-fluorouracil. other hsa-mir-423 "Carcinoma, Laryngeal" 25337209 microRNA-423-3p promotes tumor progression via modulation of AdipoR2 in laryngeal carcinoma. other hsa-mir-29b Osteosarcoma 25337211 A key role of microRNA-29b in suppression of osteosarcoma cell proliferation and migration via modulation of VEGF. other hsa-mir-30c Lung Neoplasms 25340791 "Specifically, miR-30c, a FHIT-upregulated microRNA, contributes to FHIT function in suppression of EMT and metastasis" other hsa-mir-92a Glioma 25342742 We conclude that glioma-derived miR-92a induces IL-6(+) IL-10(+) NKT cells; this fraction of NKT cells can suppress cytotoxic CD8(+) T cells. other hsa-mir-29b Aortic Aneurysm 25342766 Battle of the bulge: miR-195 versus miR-29b in aortic aneurysm. other hsa-mir-382 Osteosarcoma 25344865 miR-382 inhibits tumor growth and enhance chemosensitivity in osteosarcoma. other hsa-mir-9 "Carcinoma, Cervical" 25344913 Activation of miR-9 by human papillomavirus in cervical cancer. other hsa-mir-126 "Carcinoma, Hepatocellular" 25345948 Expression of miR-126/miR-126* in hepatocelluar carcinoma and its correlation with clinical outcomes. other hsa-mir-939 "Squamous Cell Carcinoma, Esophageal" 25346128 Expression of microRNA-939 and its correlation with prognosis in esophageal squamous cell carcinoma. other hsa-mir-23a Neoplasms [unspecific] 25347474 Targeting miR-23a in CD8+ cytotoxic T lymphocytes prevents tumor-dependent immunosuppression. other hsa-mir-34a Medulloblastoma 25348795 MiR-34a deficiency accelerates medulloblastoma formation in vivo. other hsa-mir-146a Systemic Lupus Erythematosus 25349113 The miR-146a polymorphism and susceptibility to systemic lupus erythematosus and rheumatoid arthritis : a meta-analysis. other hsa-mir-132 Nervous System Diseases [unspecific] 25351997 Chronic infection of Toxoplasma gondii downregulates miR-132 expression in multiple brain regions in a sex-dependent manner. other hsa-mir-24 "Aortic Aneurysm, Abdominal" 25358394 miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development. other hsa-mir-106b Melanoma 25361006 Down-regulation of miRNA-106b inhibits growth of melanoma cells by promoting G1-phase cell cycle arrest and reactivation of p21/WAF1/Cip1 protein. other hsa-mir-34a Colorectal Carcinoma 25362853 miR-34a-5p suppresses colorectal cancer metastasis and predicts recurrence in patients with stage II/III colorectal cancer. other hsa-mir-200c Prostate Neoplasms 25363395 Effects of miR-200c on the migration and invasion abilities of human prostate cancer Du145 cells and the corresponding mechanism. other hsa-mir-214 Neoplasms [unspecific] 25364765 "By contrast, miR-24, miR-125b, miR-195, and miR-214 function as oncogenic or tumor suppressor miRNAs in a cancer (sub)type-dependent manner." other hsa-mir-24 Neoplasms [unspecific] 25364765 "By contrast, miR-24, miR-125b, miR-195, and miR-214 function as oncogenic or tumor suppressor miRNAs in a cancer (sub)type-dependent manner." other hsa-mir-21 "Carcinoma, Ovarian, Clear Cell" 25366985 MicroRNA-21 is a candidate driver gene for 17q23-25 amplification in ovarian clear cell carcinoma. other hsa-mir-29 "Carcinoma, Hepatocellular" 25367851 Negative feedback of miR-29 family TET1 involves in hepatocellular cancer. other hsa-mir-509 "Leukemia, Lymphoblastic" 25368993 Regulation of RAB5C is important for the growth inhibitory effects of MiR-509 in human precursor-B acute lymphoblastic leukemia. other hsa-mir-145 Multiple Myeloma 25369735 Synthetic miR-145 mimic inhibits multiple myeloma cell growth in vitro and in vivo. other hsa-mir-93 Colorectal Carcinoma 25371073 MicroRNA-93 suppress colorectal cancer development via Wnt/¦Â-catenin pathway downregulating. other hsa-mir-25 Prostate Neoplasms 25372501 "These effects were strongly associated with changes in reduced expression of the miR-106b cluster (miR-106b, miR-93, and miR-25)" other hsa-mir-93 Prostate Neoplasms 25372501 "These effects were strongly associated with changes in reduced expression of the miR-106b cluster (miR-106b, miR-93, and miR-25)" other hsa-mir-1 Glioblastoma 25374033 Targeted delivery of tumor suppressor microRNA-1 by transferrin-conjugated lipopolyplex nanoparticles to patient-derived glioblastoma stem cells. other hsa-mir-9 Neoplasms [unspecific] 25375090 MicroRNA-9 promotes tumor metastasis via repressing E-cadherin in esophageal squamous cell carcinoma. other hsa-mir-21 Neoplasms [unspecific] 25376700 MicroRNA-21 and the clinical outcomes of various carcinomas: a systematic review and meta-analysis. other hsa-mir-18a Colorectal Carcinoma 25379703 miR-18a inhibits CDC42 and plays a tumour suppressor role in colorectal cancer cells. other hsa-mir-410 Osteosarcoma 25385479 VEGF-mediated suppression of cell proliferation and invasion by miR-410 in osteosarcoma. other hsa-mir-130b "Carcinoma, Hepatocellular" 25387077 MicroRNA-130b promotes cell aggressiveness by inhibiting peroxisome proliferator-activated receptor gamma in human hepatocellular carcinoma. other hsa-mir-451 Osteosarcoma 25391425 miR-451 may play an important role in tumor growth and metastasis in osteosarcoma. other hsa-mir-193a Lung Neoplasms 25391651 our findings provide the first clues regarding the role of miR-193a-3p as a tumor suppressor in lung cancer through the inhibition of ERBB4 translation. other hsa-mir-107 Kidney Diseases [unspecific] 25392232 "new strategies for probing autonomic circulatory control and ultimately, susceptibility to hypertensive renal sequelae." other hsa-mir-9 Gastric Neoplasms 25395097 "membranous ALCAM expression and high serum sALCAM levels are independent prognostic markers of poor survival for patients with GC, and that the overexpression of ALCAM may be due to the downregulation of miR-9." other hsa-mir-34a Atherosclerosis 25395581 miR-34a is involved in the flow-dependent regulation of endothelial inflammation. other hsa-mir-200 Breast Neoplasms 25401471 metastatic capability can be transferred by the uptake of extracellular vesicles. other hsa-mir-122 Hepatitis C Virus Infection 25403145 "Our study provides insight into the interaction between miR-122 and HCV, including viral adaptation to reduced miR-122 bioavailability, and has implications for the development of anti-miR-122-based HCV drugs." other hsa-mir-125b Neoplasms [unspecific] 25403182 these findings illuminate miR-125b as an important microRNA regulator that is shared between normal skin progenitors and their early malignant counterparts. other hsa-mir-141 Neoplasms [unspecific] 25403569 our comprehensive pan-cancer analysis provided not only biological insights into metastasis but also brought to bear the clinical relevance of the proposed recurrent miRNA-gene associations. other hsa-mir-200 Neoplasms [unspecific] 25403569 our comprehensive pan-cancer analysis provided not only biological insights into metastasis but also brought to bear the clinical relevance of the proposed recurrent miRNA-gene associations. other hsa-mir-429 Neoplasms [unspecific] 25403569 our comprehensive pan-cancer analysis provided not only biological insights into metastasis but also brought to bear the clinical relevance of the proposed recurrent miRNA-gene associations. other hsa-mir-375 "Carcinoma, Esophageal" 25404787 The findings from this meta-analysis suggest that miR-375 expression is associated with OS of patients with malignant tumors and could be a useful clinical prognostic biomarker. other hsa-mir-23b Bladder Neoplasms 25405368 RNA networks regulated by tumor-suppressive miR-23b/27b provide new insights into the potential mechanisms of BC oncogenesis and metastasis. other hsa-mir-27b Bladder Neoplasms 25405368 RNA networks regulated by tumor-suppressive miR-23b/27b provide new insights into the potential mechanisms of BC oncogenesis and metastasis. other hsa-mir-429 Breast Neoplasms 25405387 our results offer an opportunity for further understanding of the recondite mechanisms underlying the bone metastasis of breast cancer. other hsa-let-7a Cholesteatoma 25405753 reveal the crucial role of let-7a miRNA in the inhibition of growth and invasion of cholesteatoma keratinocytes. other hsa-mir-21 Cholesteatoma 25405753 reveal the crucial role of let-7a miRNA in the inhibition of growth and invasion of cholesteatoma keratinocytes. other hsa-let-7f Nervous System Diseases [unspecific] 25406171 EW-induced mitochondrial respiratory suppression was exacerbated by TSA treatment in a manner that was attenuated by let-7f antagomir cotreatment. other hsa-mir-183 Prostate Neoplasms 25409297 "miRNAs 200b, 30a, 1, and 183 and the genes Twist1 and Vimentin might play important roles in the progression of prostate cancer and may eventually become important prognostic markers." other hsa-mir-203 Prostate Neoplasms 25409297 "miRNAs 200b, 30a, 1, and 183 and the genes Twist1 and Vimentin might play important roles in the progression of prostate cancer and may eventually become important prognostic markers." other hsa-mir-205 Prostate Neoplasms 25409297 "miRNAs 200b, 30a, 1, and 183 and the genes Twist1 and Vimentin might play important roles in the progression of prostate cancer and may eventually become important prognostic markers." other hsa-mir-21 Prostate Neoplasms 25409297 "miRNAs 200b, 30a, 1, and 183 and the genes Twist1 and Vimentin might play important roles in the progression of prostate cancer and may eventually become important prognostic markers." other hsa-mir-373 Prostate Neoplasms 25409297 "miRNAs 200b, 30a, 1, and 183 and the genes Twist1 and Vimentin might play important roles in the progression of prostate cancer and may eventually become important prognostic markers." other hsa-mir-204 Mesial Temporal Lobe Epilepsy 25410734 miR-204 and miR-218 are developmentally regulated in the hippocampus and may contribute to the molecular mechanisms underlying the pathogenesis of MTLE and HS. other hsa-mir-218 Mesial Temporal Lobe Epilepsy 25410734 miR-204 and miR-218 are developmentally regulated in the hippocampus and may contribute to the molecular mechanisms underlying the pathogenesis of MTLE and HS. other hsa-mir-106b Coronary Artery Disease 25415674 "a relationship between the miR-17-92 family and lipid metabolism, which merits further study." other hsa-mir-17 Coronary Artery Disease 25415674 "a relationship between the miR-17-93 family and lipid metabolism, which merits further study." other hsa-mir-18a Coronary Artery Disease 25415674 "a relationship between the miR-17-94 family and lipid metabolism, which merits further study." other hsa-mir-92a Coronary Artery Disease 25415674 "a relationship between the miR-17-95 family and lipid metabolism, which merits further study." other hsa-mir-449b Prostate Neoplasms 25416653 High miR-449b expression was shown to be an independent predictor of biochemical recurrence after radical prostatectomy. other hsa-mir-200a Colorectal Carcinoma 25422078 "PZH can inhibit metastasis of colorectal cancer cells via modulating TGF-¦Â1/ZEB/miR-200 signaling network, which might be one of the mechanisms whereby PZH exerts its anticancer function." other hsa-mir-200b Colorectal Carcinoma 25422078 "PZH can inhibit metastasis of colorectal cancer cells via modulating TGF-¦Â1/ZEB/miR-200 signaling network, which might be one of the mechanisms whereby PZH exerts its anticancer function." other hsa-mir-200c Colorectal Carcinoma 25422078 "PZH can inhibit metastasis of colorectal cancer cells via modulating TGF-¦Â1/ZEB/miR-200 signaling network, which might be one of the mechanisms whereby PZH exerts its anticancer function." other hsa-mir-449a "Carcinoma, Lung, Non-Small-Cell" 25424357 The tumor suppression role of microRNA-449a could be due to its promotion of tumor cell proliferation and its inhibition of tumor cell apoptosis. other hsa-mir-141 "Carcinoma, Hepatocellular" 25425543 miR-141 functions as a tumor suppressor in HCC cells through the inhibition of HNF-3¦Â translation. other hsa-mir-10b Neoplasms [unspecific] 25426550 "miR-520d-5p leads to reduced proliferation of tumor cells, and that high levels of miR-520d-5p correlate with higher survival rates of cancer patients." other hsa-mir-520d Neoplasms [unspecific] 25426550 "miR-520d-5p leads to reduced proliferation of tumor cells, and that high levels of miR-520d-5p correlate with higher survival rates of cancer patients." other hsa-mir-155 "Leukemia, Myeloid, Acute" 25428263 this 3-microRNA scoring system is simple and powerful for risk stratification of de novo AML patients. other hsa-mir-203 "Leukemia, Myeloid, Acute" 25428263 this 3-microRNA scoring system is simple and powerful for risk stratification of de novo AML patients. other hsa-mir-9 "Leukemia, Myeloid, Acute" 25428263 this 3-microRNA scoring system is simple and powerful for risk stratification of de novo AML patients. other hsa-mir-23a Neoplasms [unspecific] 25429623 HSP70 could be beneficial to tumor cells by helping to maintain the expression of oncogenic miRNAs under conditions of cellular stress. other hsa-mir-210 Tibial Meniscus Injuries 25430980 An intra-articular injection of ds miR-210 was effective in the healing of the damaged white zone meniscus through promotion of the collagen type 2 production from meniscus cells and through upregulated of VEGF and FGF2 from synovial cells. other hsa-mir-193b Psoriasis 25431026 "the altered local miRNA changes seen in the RD are reflected in the circulating immune cells, suggesting that miRNAs may contribute to the pathogenesis of psoriasis." other hsa-mir-223 Psoriasis 25431026 "the altered local miRNA changes seen in the RD are reflected in the circulating immune cells, suggesting that miRNAs may contribute to the pathogenesis of psoriasis." other hsa-mir-26a Breast Neoplasms 25434799 miR-26a functions as a tumour suppressor in TNBC development and serves as a prognostic marker for breast cancer. other hsa-mir-1181 Pancreatic Neoplasms 25444909 miR-1181 plays a vital role in inhibiting the CSCs-like phenotypes in pancreatic cancer and might represent a potential target for anti-pancreatic cancer. other hsa-mir-23a Breast Neoplasms 25445205 "The overall concordance rates between miR-23a with HRG and FOXM1 tissue RNAs were 91% and 79%, respectively. The median follow-up period was 49 months. mi-23a and HRG RNA were significant independent prognostic markers in relapse-free survival. miR-23a may have an oncogenic function and enhance BC progression by directly activating FOXM1 and HRG at RNA level." other hsa-mir-21 Neoplasms [unspecific] 25445583 "Further, during the transformation of HBE cells, inhibition of miR-21 with an miR-21 inhibitor increased levels of PDCD4, an inhibitor of neoplastic transformation;" other hsa-mir-134 "Carcinoma, Embryonal" 25447206 FOXM1 is essential for human pluripotent stem cells and miR-134 attenuates its expression during differentiation. other hsa-mir-21 "Carcinoma, Hepatocellular" 25447674 "I3C could function as a miR-21 regulator, leading to repression of the PTEN/AKT pathway and opening a new avenue for eradication of drug-resistant cells, thus potentially helping to improve the therapeutic outcome in patients diagnosed with HCC." other hsa-mir-221 "Carcinoma, Hepatocellular" 25447674 "I3C could function as a miR-19 regulator, leading to repression of the PTEN/AKT pathway and opening a new avenue for eradication of drug-resistant cells, thus potentially helping to improve the therapeutic outcome in patients diagnosed with HCC." other hsa-mir-222 "Carcinoma, Hepatocellular" 25447674 "I3C could function as a miR-20 regulator, leading to repression of the PTEN/AKT pathway and opening a new avenue for eradication of drug-resistant cells, thus potentially helping to improve the therapeutic outcome in patients diagnosed with HCC." other hsa-mir-221 Breast Neoplasms 25447917 miR-221-3p may give crucial information about molecular mechanism of the disease upon PAK1 activity or different mechanisms with respect to histopathology and severity of breast cancer. other hsa-mir-197 Lung Neoplasms 25451482 ER stress plays a major role in STAT6-induced apoptosis. other hsa-mir-320a Colorectal Carcinoma 25458952 "microRNA-320b may function in competing with microRNA-320a. Thus, our study has proposed one novel mechanism for controlling colorectal cancer proliferation and invasion through homologous competition between microRNAs. This mechanism may be important for colorectal cancer metastasis." other hsa-mir-320b Colorectal Carcinoma 25458952 "microRNA-320b may function in competing with microRNA-320a. Thus, our study has proposed one novel mechanism for controlling colorectal cancer proliferation and invasion through homologous competition between microRNAs. This mechanism may be important for colorectal cancer metastasis." other hsa-mir-126 Prostate Neoplasms 25462564 The regulation of these factors by miR-126 and miR-149 is essential for syndecan-1-mediated development of androgen-refractory prostate cancer. other hsa-mir-149 Prostate Neoplasms 25462564 The regulation of these factors by miR-126 and miR-149 is essential for syndecan-1-mediated development of androgen-refractory prostate cancer. other hsa-mir-223 Atherosclerosis 25463083 "MiR-223-mediated suppression of TF expression provides a novel molecular mechanism for the regulation of coagulation cascade, and suggests a clue against thrombogenesis during the process of atherosclerotic plaque rupture." other hsa-mir-29a Heart Failure 25464262 "MicroRNA-29a (miR-29a), a key regulator of tissue fibrosis, was highly expressed in the exosomes and the marginal area of the RIC group." other hsa-mir-145 Acute Myocardial Infarction 25465803 Circulating miR-145 may be a novel biomarker for predicting long-term outcome after acute myocardial infarction. other hsa-mir-144 Breast Neoplasms 25465851 "4 miRNAs that are generally dysregulated in human pathologies. Although these markers are not specific to certain diseases they may add to the diagnosis in combination with other markers, building a specific signature. Besides these dysregulated miRNAs, we propose a set of constant miRNAs that may be used as control markers." other hsa-mir-146a Enterovirus Infection 25469565 EV71-induced cell apoptosis is partly governed by altered miRNAs. other hsa-mir-370 Enterovirus Infection 25469565 EV71-induced cell apoptosis is partly governed by altered miRNAs. other hsa-mir-122 "Fatty Liver, Non-Alcoholic" 25470250 "Finally, the liver appears to be an important source of circulating EVs in NAFLD animals as evidenced by the enrichment in blood with miR-122 and 192--two microRNAs previously described in chronic liver diseases, coupled with a corresponding decrease in expression of these microRNAs in the liver." other hsa-mir-143 Colorectal Carcinoma 25474488 a role of the miR-143/145 cluster as a tumor suppressor in colorectal cancer through the inhibition of IGF1R translation. other hsa-mir-145 Colorectal Carcinoma 25474488 a role of the miR-143/145 cluster as a tumor suppressor in colorectal cancer through the inhibition of IGF1R translation. other hsa-mir-196b Leukemia 25475721 "miRNA-196b may play an essential role in the development of MLL-associated leukemias through inhibiting cell differentiation and apoptosis, while promoting cell proliferation." other hsa-mir-153 Lung Neoplasms 25475731 significance of miR-153 and ADAM19 in the development and progression of NSCLC. other hsa-mir-145 Neoplasms [unspecific] 25476854 large-scale prospective studies and additional improvements are urgently needed to confirm our findings and its utilization for routine clinical diagnosis in future. other hsa-mir-143 Neoplasms [unspecific] 25477374 differences in these tumor suppressors might contribute to regional differences in normal colonic gene expression and modulate site-specific differences in malignant predisposition. other hsa-mir-145 Neoplasms [unspecific] 25477374 differences in these tumor suppressors might contribute to regional differences in normal colonic gene expression and modulate site-specific differences in malignant predisposition. other hsa-mir-200a "Carcinoma, Hepatocellular" 25482402 miR-200a may be recognized as a novel potential biomarker to predict the survival of patients with HCCs following liver transplantation. other hsa-mir-155 Breast Neoplasms 25484137 a role of miR-155 in thiamine homeostasis and suggests a function of this oncogenic miRNA on breast cancer metabolism. other hsa-mir-21 Peripheral Nerve Injury 25484256 miR-21 and miR-222 inhibited neuronal apoptosis at least partially through suppressing TIMP3 after peripheral nerve injury. other hsa-mir-222 Peripheral Nerve Injury 25484256 miR-21 and miR-222 inhibited neuronal apoptosis at least partially through suppressing TIMP3 after peripheral nerve injury. other hsa-mir-146a Neurodegenerative Diseases [unspecific] 25484882 "We particularly focus on the role played by miR-146a in the regulation and signaling mediated by one of the main pattern recognition receptors, toll/IL-1 receptors (TLRs)." other hsa-mir-143 Neoplasms [unspecific] 25486198 "identify new molecules and mechanisms involved in the DDR, and to examine their role in tumor suppression and the clinical outcome of cancer patients." other hsa-mir-16 Neoplasms [unspecific] 25486198 "identify new molecules and mechanisms involved in the DDR, and to examine their role in tumor suppression and the clinical outcome of cancer patients." other hsa-mir-34 Neoplasms [unspecific] 25486198 "identify new molecules and mechanisms involved in the DDR, and to examine their role in tumor suppression and the clinical outcome of cancer patients." other hsa-mir-203 Choriocarcinoma 25486432 "Besides EZH2, increases in miR-203 expression in the crypts at days 6 and 12 post infection correlated with reduced levels of its target WIF1; overexpression of miR-203 in primary colonocytes decreased WIF1 mRNA and protein levels." other hsa-mir-142 Multiple Sclerosis 25486582 "AHSCT normalizes microRNA and gene expression, thereby improving the immunoregulatory network. These mechanisms may be important for disease control in the early periods after AHSCT." other hsa-mir-155 Multiple Sclerosis 25486582 "AHSCT normalizes microRNA and gene expression, thereby improving the immunoregulatory network. These mechanisms may be important for disease control in the early periods after AHSCT." other hsa-mir-16 Multiple Sclerosis 25486582 "AHSCT normalizes microRNA and gene expression, thereby improving the immunoregulatory network. These mechanisms may be important for disease control in the early periods after AHSCT." other hsa-mir-155 Neoplasms [unspecific] 25486872 miR-155 expression is associated with chemoimmunotherapy outcome and is modulated by Bruton's tyrosine kinase inhibition with Ibrutinib. other hsa-mir-148a Chronic Inflammation 25486906 "Twist1 and T-bet not only control the differentiation and function of Th1 cells, but also their persistence in chronic inflammation." other hsa-mir-29a Human Immunodeficiency Virus Infection 25486977 links miR-29a to viral latency and suggests another approach to activate and destroy latent HIV-1 reservoirs. other hsa-mir-34a Osteosarcoma 25490093 cell response to etoposide-induced DNA damage was not compromised in cells with dominant-negative p53 expression. other hsa-mir-221 Melanoma 25492219 The hair shaft miR-221 levels were significantly higher in patients with MM than controls. other hsa-mir-21 Rectal Neoplasms 25496125 "miR-21-5p as a promising predictive biomarker, which should aid in the selection of patients with cCR to nCRT that potentially could be spared from radical surgery." other hsa-mir-21 Pleural Mesothelioma 25497279 a novel 6-microRNA signature (miR-Score) that can accurately predict prognosis of MPM patients. other hsa-mir-221 Pleural Mesothelioma 25497279 a novel 6-microRNA signature (miR-Score) that can accurately predict prognosis of MPM patients. other hsa-mir-222 Pleural Mesothelioma 25497279 a novel 6-microRNA signature (miR-Score) that can accurately predict prognosis of MPM patients. other hsa-mir-23a Pleural Mesothelioma 25497279 a novel 6-microRNA signature (miR-Score) that can accurately predict prognosis of MPM patients. other hsa-mir-30e Pleural Mesothelioma 25497279 a novel 6-microRNA signature (miR-Score) that can accurately predict prognosis of MPM patients. other hsa-mir-31 Pleural Mesothelioma 25497279 a novel 6-microRNA signature (miR-Score) that can accurately predict prognosis of MPM patients. other hsa-mir-137 Lung Neoplasms 25498886 miR-137 may be an independent favorable prognostic factor in NSCLC patients. other hsa-mir-494 Oral Neoplasms 25500095 the role of miR-494 as a tumor suppressor miRNA in oral cancer. other hsa-mir-2909 Immune System Disease [unspecific] 25500259 a mechanistic-pathway is proposed that links the epigenomic-interplay between MALT1 and miR-2909. other hsa-mir-206 Pancreatic Adenocarcinoma 25500542 "miR-206 as a pleiotropic modulator of different hallmarks of cancer, and as such raising the intriguing possibility that miR-206 may be an attractive candidate for miRNA-based anticancer therapies." other hsa-mir-23a "Squamous Cell Carcinoma, Tongue" 25501015 the molecular mechanisms underlying TSCC chemoresistance. other hsa-mir-210 Osteoporosis 25503465 miR-210 played an important role in ameliorating the estrogen deficiency caused-postmenopausal osteoporosis through promotion the VEGF expression and osteoblast differentiation. other hsa-mir-130 Pulmonary Hypertension 25505270 olecular cross-talk among the diverse cellular populations involved in PH. other hsa-mir-301 Pulmonary Hypertension 25505270 olecular cross-talk among the diverse cellular populations involved in PH. other hsa-mir-21 Glioma 25510379 An independent meta-analysis of five included studies was conducted to evaluate the diagnostic efficacy of miR-21 in patients with glioma other hsa-mir-27a Obesity 25510894 "Correspondingly, the expression of miR-27a and miR-27b were up-regulated by persimmon tannin from Day 2 to Day 8 significantly." other hsa-mir-27b Obesity 25510894 "Correspondingly, the expression of miR-27a and miR-27b were up-regulated by persimmon tannin from Day 2 to Day 8 significantly." other hsa-mir-7 Breast Neoplasms 25511742 miR-7-5p has a critical function through blocking REG¦Ã in breast cancer cells. other hsa-mir-25 "Carcinoma, Neuroendocrine" 25512615 "The pathogenesis of prostatic SCNC involves a p53 and Aurora Kinase A signaling mechanism, both potentially targetable pathways." other hsa-mir-17 Retinoblastoma 25513843 "the antiproliferative property of pri-apt in RB cell lines, which can be readily modified by developing appropriate vectors for the delivery of the aptamer specifically to cancer cells." other hsa-mir-18a Retinoblastoma 25513843 "the antiproliferative property of pri-apt in RB cell lines, which can be readily modified by developing appropriate vectors for the delivery of the aptamer specifically to cancer cells." other hsa-mir-19b Retinoblastoma 25513843 "the antiproliferative property of pri-apt in RB cell lines, which can be readily modified by developing appropriate vectors for the delivery of the aptamer specifically to cancer cells." other hsa-mir-92a Colorectal Carcinoma 25515201 miR-92a is involved in lymph node metastasis of CRC patients through PTEN-regulated PI3K/AKT signaling pathway. other hsa-mir-122 Obesity 25515554 Elevated circulating miR-122 is positively associated with obesity and insulin resistance in young adults. These findings provide a better understanding regarding the role of miRNAs in adiposity and insulin sensitivity. other hsa-mir-210 Endometriosis 25516558 "This work was supported in part by Grants-in-Aid for Scientific Research from the Japan Society for the Promotion of Science (no. 13237327 to K.N., no. 25861500 to Y.K. and no. 23592407 to H.N.). There are no conflicts of interest to declare." other hsa-mir-193b Laryngeal Neoplasms 25517434 Culturing the IL-10(+) Mos with effector CD8(+) T cells resulted in the suppression of CD8(+) T-cell activitie other hsa-mir-99 Heart Failure 25517466 concept for identifying and activating conserved molecular programs to regenerate the damaged heart. other hsa-mir-133a "Squamous Cell Carcinoma, Lung" 25518741 Further analysis of novel cancer signaling pathways modulated by the tumor-suppressive cluster miR-1/133a will provide insights into the molecular mechanisms of lung-SCC oncogenesis and metastasis other hsa-mir-100 Coronary Atherosclerosis 25519160 miR-100 might be released into the coronary circulation from vulnerable coronary plaques. This study provides insights into the role of miRNAs in coronary atherosclerotic disease. other hsa-mir-1226 Lung Neoplasms 25519225 the screening approach used in this study can identify clinically relevant synthetic lethal interactions and that vitamin D receptor agonists may show enhanced efficacy in p53-negative lung cancer patients. other hsa-mir-92a Lung Neoplasms 25519225 the screening approach used in this study can identify clinically relevant synthetic lethal interactions and that vitamin D receptor agonists may show enhanced efficacy in p53-negative lung cancer patients. other hsa-mir-155 "Adenocarcinoma, Pancreatic Ductal" 25520858 "MiR-21, miR-155 and miR-216 in stool have the potential of becoming biomarkers for screening PDAC." other hsa-mir-126 "Squamous Cell Carcinoma, Lung" 25521201 rule discovery followed by distance separation is a powerful computational method to identify reliable miRNA biomarkers. The visualization of the rules and the clear separation between the normal and cancer samples by our rules will help biology experts for their analysis and biological interpretation. other hsa-mir-205 "Squamous Cell Carcinoma, Lung" 25521201 rule discovery followed by distance separation is a powerful computational method to identify reliable miRNA biomarkers. The visualization of the rules and the clear separation between the normal and cancer samples by our rules will help biology experts for their analysis and biological interpretation. other hsa-mir-98 "Squamous Cell Carcinoma, Lung" 25521201 rule discovery followed by distance separation is a powerful computational method to identify reliable miRNA biomarkers. The visualization of the rules and the clear separation between the normal and cancer samples by our rules will help biology experts for their analysis and biological interpretation. other hsa-mir-375 Tongue Neoplasms 25521291 the four anti-cancer drugs examined in this study induce the expression of tumor suppressor miR-375 in tongue cancer. other hsa-mir-155 Breast Neoplasms 25523096 "the miRNA and isomiR levels in BC, which indicates biological roles of isomiRs." other hsa-mir-21 Breast Neoplasms 25523096 "the miRNA and isomiR levels in BC, which indicates biological roles of isomiRs." other hsa-mir-221 Breast Neoplasms 25523096 "the miRNA and isomiR levels in BC, which indicates biological roles of isomiRs." other hsa-mir-25 Breast Neoplasms 25523096 "the miRNA and isomiR levels in BC, which indicates biological roles of isomiRs." other hsa-mir-30e Breast Neoplasms 25523096 "the miRNA and isomiR levels in BC, which indicates biological roles of isomiRs." other hsa-mir-143 Myeloproliferative Neoplasms 25527813 Our findings of aberrant miR-143 expression support the concept that factors other than JAK2 V617F mutation may contribute to the pathogenesis and some clinical signs of MPNs. other hsa-mir-134 "Carcinoma, Endometrial" 25528443 endogenous miR-134 regulation in HuECSCs may suppress tumourigenesis in human endometrial carcinoma. other hsa-mir-22 Vascular Disease [unspecific] 25530680 Mox-LDL interferes with parameters associated with angiogenesis. They suggest that high LDL levels in patients would impair their endothelial cell capacity to cope with a damaged endothelium contributing negatively to the progression of the atheroma plaque. other hsa-mir-486 "Leukemia, Myeloid" 25533034 "miR-486-5p cooperates with GATA1s in supporting the growth and survival, and the aberrant erythroid phenotype of the megakaryocytic leukemias of DS." other hsa-mir-21 Ischemia-Reperfusion Injury 25536091 isoflurane mediates protection of cardiomyocytes against oxidative stress via an miR-21/programmed cell death protein 4 pathway. other hsa-mir-146a Ovarian Neoplasms 25537514 a proportion of patients with wild-type BRCA1/2 ovarian cancers benefit from platinum-based chemotherapy and that the patients who benefit could be predicted from BRCA1/2-directed miRNA signature. other hsa-mir-148a Ovarian Neoplasms 25537514 a proportion of patients with wild-type BRCA1/2 ovarian cancers benefit from platinum-based chemotherapy and that the patients who benefit could be predicted from BRCA1/2-directed miRNA signature. other hsa-mir-545 Ovarian Neoplasms 25537514 a proportion of patients with wild-type BRCA1/2 ovarian cancers benefit from platinum-based chemotherapy and that the patients who benefit could be predicted from BRCA1/2-directed miRNA signature. other hsa-mir-92b Gastric Neoplasms 25537895 "miR-92b promotes the migration, adhesion and invasion of human gastric cancer cell line SGC7901 by mediating epithelial-mesenchymal transition, and may accelerate tumor cell metastasis via signaling pathways other than PI3K/Akt pathway." other hsa-let-7a Cervical Neoplasms 25539644 "existence of a functional loop involving Let-7a, STAT3 and miR-21 which were found potentially regulated by viral oncoprotein E6." other hsa-mir-21 Cervical Neoplasms 25539644 "existence of a functional loop involving Let-7a, STAT3 and miR-21 which were found potentially regulated by viral oncoprotein E6." other hsa-mir-125b Breast Neoplasms 25539763 "context-dependent roles are not clear in breast cancer, a diverse expression pattern of ALCAM mRNA was detected in a panel of breast cancer patient samples. Differentially expressed/regulated cancer-related genes upon miR-125b expression along with the significant increase of ALCAM are of future interest to understand how deregulated expression of miR-125b may have a tumor suppressor role in breast and other cancers." other hsa-mir-15a Neoplasms [unspecific] 25540364 viral RNAs can exert their functions as competing endogenous RNAs (ceRNAs) toward microRNA and participate in important cellular processes. other hsa-mir-155 "Lymphoma, B-Cell" 25541152 "Importantly, the targeting of miRNAs (like use of anti-miR-155 or miR-34a mimic) could provide a novel therapeutic approach as evidenced by tumour regression in xenograft mouse models and initial promising data from clinical trials." other hsa-mir-34a "Lymphoma, B-Cell" 25541152 "Importantly, the targeting of miRNAs (like use of anti-miR-155 or miR-34a mimic) could provide a novel therapeutic approach as evidenced by tumour regression in xenograft mouse models and initial promising data from clinical trials." other hsa-mir-125a Glioblastoma 25542152 "TAZ deregulation in glioma cells, and also demonstrated a tumor suppressor role of miR-125a-5p in glioblastoma cells." other hsa-mir-31 Colorectal Carcinoma 25543122 Overexpression of miR-31 and -182 in CRC leads to more aggressive cancer. other hsa-mir-21 "Leukemia, Myeloid, Acute" 25543261 deregulated miR-21 expression may contribute to disease pathogenesis in NPM1-mutated AMLs other hsa-mir-33a Lung Neoplasms 25544258 the treatment of lung cancer and clarify the mechanism of its progression. other hsa-mir-133a Muscle Diseases [unspecific] 25547110 human skeletal muscle differentiation and development in healthy and disease states. other hsa-mir-133b Muscle Diseases [unspecific] 25547110 human skeletal muscle differentiation and development in healthy and disease states. other hsa-mir-206 Muscle Diseases [unspecific] 25547110 human skeletal muscle differentiation and development in healthy and disease states. other hsa-mir-20a Muscle Diseases [unspecific] 25547110 human skeletal muscle differentiation and development in healthy and disease states. other hsa-mir-26 Muscle Diseases [unspecific] 25547110 human skeletal muscle differentiation and development in healthy and disease states. other hsa-mir-30 Muscle Diseases [unspecific] 25547110 human skeletal muscle differentiation and development in healthy and disease states. other hsa-mir-155 Neoplasms [unspecific] 25548153 "overexpression of miR-155 in tumor-specific T cells can be used to increase the effectiveness of adoptive immunotherapies in a cell-intrinsic manner without the need for life-threatening, lymphodepleting maneuvers." other hsa-mir-150 "Carcinoma, Hepatocellular" 25549355 re-expression of MMP14 in hepatoma cells partially reverses the effect of miR-150-5p in inhibiting cell invasion other hsa-mir-21 Neoplasms [unspecific] 25550434 ESCRT-I complex in the regulation of productive free uptake of anti-miRs and reveal potential avenues for improving oligonucleotide free uptake by cancer cells. other hsa-mir-193b Breast Neoplasms 25550792 "miR-193b as a novel tumor suppressor plays an important role in breast cancer progression, understanding the mechanisms could account for the aggressive behaviour of breast cancer." other hsa-mir-451 Bladder Neoplasms 25550801 "miR451 should be a tumor-suppressing gene in bladder cancer. miR-451 could maintain the bladder tumor cells in epithelial phenotype, inhibit EMT process, thereby reducing the invasion and migration of tumor cells." other hsa-mir-139 "Carcinoma, Colon" 25550849 miR-139-3p has potential as a prognostic biomarker for colon cancer. Further prospective studies are required to validate this result. other hsa-mir-145 "Adenocarcinoma, Esophageal" 25551563 "While expression of miR-145 in ESCC stopped proliferation and invasion, expression of miR-145 in EAC cells enhanced invasion and anoikis resistance. Although more work is required to understand how miR-145 conveys these effects, expression of miR-145 appears to promote EAC progression by enhancing invasion and protection against anoikis, which could in turn facilitate distant metastasis." other hsa-mir-9 "Carcinoma, Hepatocellular" 25552204 the potential of miR-9 as a novel prognostic biomarker for HCC. Large well-designed studies with diverse populations and functional evaluations are warranted to confirm and extend our findings. other hsa-mir-183 Prostate Neoplasms 25556023 the regulation of prostate-specific antigen and may eventually affect clinical decision making in prostate cancer. other hsa-mir-574 Breast Neoplasms 25560734 functional screening mediated by miRNA libraries can provide new insights into the genes essential for tamoxifen response in breast cancer. other hsa-mir-146a Liver Diseases [unspecific] 25562147 a critical role for miRNAs in the pathogenesis of NAFLD. other hsa-mir-146b Liver Diseases [unspecific] 25562147 a critical role for miRNAs in the pathogenesis of NAFLD. other hsa-mir-152 Liver Diseases [unspecific] 25562147 a critical role for miRNAs in the pathogenesis of NAFLD. other hsa-mir-200a Liver Diseases [unspecific] 25562147 a critical role for miRNAs in the pathogenesis of NAFLD. other hsa-mir-200b Liver Diseases [unspecific] 25562147 a critical role for miRNAs in the pathogenesis of NAFLD. other hsa-mir-200c Liver Diseases [unspecific] 25562147 a critical role for miRNAs in the pathogenesis of NAFLD. other hsa-mir-222 Breast Neoplasms 25562151 "¦Â-elemene could influence MDR related miRNA expression and subsequently regulate the expression of the target genes PTEN and Pgp, which may lead to reduction of the viability of the chemo-resistant breast cancer cells." other hsa-mir-29a Breast Neoplasms 25562151 "¦Â-elemene could influence MDR related miRNA expression and subsequently regulate the expression of the target genes PTEN and Pgp, which may lead to reduction of the viability of the chemo-resistant breast cancer cells." other hsa-mir-34a Breast Neoplasms 25562151 "¦Â-elemene could influence MDR related miRNA expression and subsequently regulate the expression of the target genes PTEN and Pgp, which may lead to reduction of the viability of the chemo-resistant breast cancer cells." other hsa-mir-452 Breast Neoplasms 25562151 "¦Â-elemene could influence MDR related miRNA expression and subsequently regulate the expression of the target genes PTEN and Pgp, which may lead to reduction of the viability of the chemo-resistant breast cancer cells." other hsa-mir-223 Liver Failure 25562161 "miR-223 acted to inhibit IL-1¦Â production via AIM2 pathway, suppressing Kupffer cells pro-inflammatory activation at the early stage of ALF. Thus, it played an important role in the pathogenesis of ALF." other hsa-mir-212 Osteosarcoma 25562164 The miR-212/Sox4 interaction plays an important role of in the osteosarcoma progression. other hsa-mir-145 Glioblastoma 25564360 Synthetic miR-145 Mimic Enhances the Cytotoxic Effect of the Antiangiogenic Drug Sunitinib in Glioblastoma. other hsa-mir-215 Renal Fibrosis 25565137 MicroRNA-215 Regulates Fibroblast Function: Insights from a Human Fibrotic Disease. other hsa-mir-192 Bladder Neoplasms 25566965 miR-192 may be a suppressor for bladder cancer cells by cell cycle regulation. other hsa-mir-28 "Leukemia, T-Cell" 25568327 miR-28 may play an important role in HTLV-1 transmission. other hsa-mir-218 "Carcinoma, Gallbladder" 25569100 "CCAT1 is a driver of malignancy, which acts in part through 'spongeing' miRNA-218-5p." other hsa-mir-34a Bladder Neoplasms 25572695 polyphenols in PRE can be potential molecular clusters to suppress bladder cancer cell EJ proliferation via p53/miR-34a axis. other hsa-mir-125b Lung Neoplasms 25573191 miR-125b may function as an oncogene in lung cancer. other hsa-mir-214 Coronary Artery Disease 25575606 increased miR-214 level may be used to predict the presence and severity of coronary lesions in CAD patients. other hsa-mir-129 Oral Leukoplakia 25576219 "a miRNA-mRNA regulatory network associated with the malignant transformation of OLK, and screened out some miRNAs and transcription factors that may have prominent roles during OLK malignant progression." other hsa-mir-31 Oral Leukoplakia 25576219 "a miRNA-mRNA regulatory network associated with the malignant transformation of OLK, and screened out some miRNAs and transcription factors that may have prominent roles during OLK malignant progression." other hsa-mir-339 Oral Leukoplakia 25576219 "a miRNA-mRNA regulatory network associated with the malignant transformation of OLK, and screened out some miRNAs and transcription factors that may have prominent roles during OLK malignant progression." other hsa-mir-93 "Squamous Cell Carcinoma, Head and Neck" 25578493 miR-93 may be a valuable marker for the prediction of metastasis and prognosis in HNSCC. other hsa-mir-152 Neoplasms [unspecific] 25578780 XIST in GSCs and important clues for understanding the key roles of lncRNA-miRNA functionalnetwork in human glioma. other hsa-mir-210 "Leukemia, Myeloid" 25579461 The suitability of the method for biological samples was tested by detecting microRNA-210 from transfected K562 cells. other hsa-mir-34a Neoplasms [unspecific] 25579512 Regulatory mechanisms and clinical perspectives of miR-34a in cancer. other hsa-mir-21 Glioblastoma 25582055 ADAR2 is a key factor for maintaining edited-miRNA population and balancing the expression of several essential miRNAs involved in cancer. other hsa-mir-221 Glioblastoma 25582055 ADAR2 is a key factor for maintaining edited-miRNA population and balancing the expression of several essential miRNAs involved in cancer. other hsa-mir-222 Glioblastoma 25582055 ADAR2 is a key factor for maintaining edited-miRNA population and balancing the expression of several essential miRNAs involved in cancer. other hsa-mir-16 "Cardiomyopathy, Hypertrophic" 25583328 "Attenuation of microRNA-16 derepresses the cyclins D1, D2 and E1 to provoke cardiomyocyte hypertrophy." other hsa-mir-221 Bladder Neoplasms 25585941 "The expression of MMP-2, MMP-9 and VEGF-C were reduced, resulting in reduced invasiveness and infiltration capability of bladder cancer cells, thereby inhibiting the immune evasion of bladder cancer cells." other hsa-mir-200a Neoplasms [unspecific] 25586904 exposure to arsenic rapidly induces a multifaceted dedifferentiation program and miR-205 has potential to be used as a marker of\ arsenic exposure as well as a maker of early urothelial carcinoma detection. other hsa-mir-200b Neoplasms [unspecific] 25586904 exposure to arsenic rapidly induces a multifaceted dedifferentiation program and miR-205 has potential to be used as a marker of\ arsenic exposure as well as a maker of early urothelial carcinoma detection. other hsa-mir-200c Neoplasms [unspecific] 25586904 exposure to arsenic rapidly induces a multifaceted dedifferentiation program and miR-205 has potential to be used as a marker of\ arsenic exposure as well as a maker of early urothelial carcinoma detection. other hsa-mir-205 Neoplasms [unspecific] 25586904 exposure to arsenic rapidly induces a multifaceted dedifferentiation program and miR-205 has potential to be used as a marker of\ arsenic exposure as well as a maker of early urothelial carcinoma detection. other hsa-mir-29b-2 Diabetes Mellitus 25587719 The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus. other hsa-mir-1 Myocardial Infarction 25588055 Downregulation of IGF1 specific miRNA-1 and -133 but not miR-145 expression was also confirmed. other hsa-mir-15 Breast Neoplasms 25594541 the expression of the miR-15 family contributes to increased radiosensitivity of breast cancer cells by influencing G2/M checkpoint proteins. other hsa-mir-500 Gastric Neoplasms 25595906 "we report the uncovering of a novel mechanism for constitutive NF-¦ÊB activation, indicating the potentially pivotal role of miR-500 in the progression of gastric cancer." other hsa-mir-34a "Carcinoma, Hepatocellular" 25596083 the expression of miR-34a in HCC biopsy specimens has an independent predictive value of early recurrence after RFA. other hsa-mir-22 Liver Neoplasms 25596928 "bile acid-activated FXR stimulates miR-22-silenced CCNA2, a novel pathway for FXR to exert its protective effect in the gastrointestinal tract." other hsa-mir-125b Prostate Neoplasms 25597828 "use of a combination of different types of genetic markers in ejaculate together with serum PSA are at least as sensitive as those reported in DRE urine. Furthermore, a combination of serum PSA and selected miRNAs improved prediction of prostate cancer status. This approach may be helpful in triaging patients for MRI and biopsy, when confirmed by larger studies." other hsa-mir-200b Prostate Neoplasms 25597828 "use of a combination of different types of genetic markers in ejaculate together with serum PSA are at least as sensitive as those reported in DRE urine. Furthermore, a combination of serum PSA and selected miRNAs improved prediction of prostate cancer status. This approach may be helpful in triaging patients for MRI and biopsy, when confirmed by larger studies." other hsa-mir-200c Prostate Neoplasms 25597828 "use of a combination of different types of genetic markers in ejaculate together with serum PSA are at least as sensitive as those reported in DRE urine. Furthermore, a combination of serum PSA and selected miRNAs improved prediction of prostate cancer status. This approach may be helpful in triaging patients for MRI and biopsy, when confirmed by larger studies." other hsa-mir-375 Prostate Neoplasms 25597828 "use of a combination of different types of genetic markers in ejaculate together with serum PSA are at least as sensitive as those reported in DRE urine. Furthermore, a combination of serum PSA and selected miRNAs improved prediction of prostate cancer status. This approach may be helpful in triaging patients for MRI and biopsy, when confirmed by larger studies." other hsa-mir-205 "Carcinoma, Renal Cell" 25600645 how overexpression of MALAT1 confers an oncogenic function in RCC that may offer a novel theranostic marker in this disease. other hsa-mir-10b Colorectal Carcinoma 25606801 miR-10b is potentially involved in the invasion of colorectal cancer. other hsa-mir-100 Pancreatic Neoplasms 25607660 This pilot study highlights miRNAs that may aid in preoperative risk stratification of IPMNs and provides novel insights into miRNA-mediated progression to pancreatic malignancy. The miRNAs identified here and in other recent investigations warrant evaluation in biofluids in a well-powered prospective cohort of individuals newly-diagnosed with IPMNs and other pancreatic cysts and those at increased genetic risk for these lesions. other hsa-mir-126 Pancreatic Neoplasms 25607660 This pilot study highlights miRNAs that may aid in preoperative risk stratification of IPMNs and provides novel insights into miRNA-mediated progression to pancreatic malignancy. The miRNAs identified here and in other recent investigations warrant evaluation in biofluids in a well-powered prospective cohort of individuals newly-diagnosed with IPMNs and other pancreatic cysts and those at increased genetic risk for these lesions. other hsa-mir-130a Pancreatic Neoplasms 25607660 This pilot study highlights miRNAs that may aid in preoperative risk stratification of IPMNs and provides novel insights into miRNA-mediated progression to pancreatic malignancy. The miRNAs identified here and in other recent investigations warrant evaluation in biofluids in a well-powered prospective cohort of individuals newly-diagnosed with IPMNs and other pancreatic cysts and those at increased genetic risk for these lesions. other hsa-mir-342 Pancreatic Neoplasms 25607660 This pilot study highlights miRNAs that may aid in preoperative risk stratification of IPMNs and provides novel insights into miRNA-mediated progression to pancreatic malignancy. The miRNAs identified here and in other recent investigations warrant evaluation in biofluids in a well-powered prospective cohort of individuals newly-diagnosed with IPMNs and other pancreatic cysts and those at increased genetic risk for these lesions. other hsa-mir-99a Pancreatic Neoplasms 25607660 This pilot study highlights miRNAs that may aid in preoperative risk stratification of IPMNs and provides novel insights into miRNA-mediated progression to pancreatic malignancy. The miRNAs identified here and in other recent investigations warrant evaluation in biofluids in a well-powered prospective cohort of individuals newly-diagnosed with IPMNs and other pancreatic cysts and those at increased genetic risk for these lesions. other hsa-mir-99b Pancreatic Neoplasms 25607660 This pilot study highlights miRNAs that may aid in preoperative risk stratification of IPMNs and provides novel insights into miRNA-mediated progression to pancreatic malignancy. The miRNAs identified here and in other recent investigations warrant evaluation in biofluids in a well-powered prospective cohort of individuals newly-diagnosed with IPMNs and other pancreatic cysts and those at increased genetic risk for these lesions. other hsa-let-7b Colorectal Carcinoma 25611389 Genome-wide mRNA and miRNA expression profiling reveal multiple regulatory networks in colorectal cancer. other hsa-mir-375 Breast Neoplasms 25613180 biochanin A promoted ER¦Á-positive cell proliferation through miR-375 activation and this mechanism is possibly involving in a miR-375 and ER¦Á feedback loop. other hsa-mir-205 Malignant Neoplasms [unspecific] 25613953 "miRNA-205 is a promising biomarker for predicting the recurrence and progression of patients with adenocarcinomas or breast cancer. Owing to its complex roles, further relevant studies are warranted." other hsa-mir-558 Neuroblastoma 25616966 "miR-558 induces the transcriptional activation of HPSE via the binding site within promoter, thus facilitating the tumorigenesis and aggressiveness of NB." other hsa-mir-28 Neoplasms [unspecific] 25617309 miR-28-5p promotes chromosomal instability in VHL-associated cancers by inhibiting Mad2 translation. other hsa-mir-146b Atrial Fibrillation 25617731 miR-146b-5p probably acts as an intracellular mediator in the maladaptive remodeling in atrial fibrosis in atrial fibrillation. other hsa-mir-210 Gastric Neoplasms 25618442 MIR210 is often highly overexpressed in gastric cancer other hsa-mir-10b Bladder Neoplasms 25620614 "urine miR-210, miR-10b, and miR-29c are promising tumor markers for BC: bilharzial and nonbilharzial." other hsa-mir-210 Bladder Neoplasms 25620614 "urine miR-210, miR-10b, and miR-29c are promising tumor markers for BC: bilharzial and nonbilharzial." other hsa-mir-221 Bladder Neoplasms 25620614 "urine miR-210, miR-10b, and miR-29c are promising tumor markers for BC: bilharzial and nonbilharzial." other hsa-mir-23a Bladder Neoplasms 25620614 "urine miR-210, miR-10b, and miR-29c are promising tumor markers for BC: bilharzial and nonbilharzial." other hsa-mir-29c Bladder Neoplasms 25620614 "urine miR-210, miR-10b, and miR-29c are promising tumor markers for BC: bilharzial and nonbilharzial." other hsa-mir-122 Breast Neoplasms 25621950 "by modifying glucose utilization by recipient premetastatic niche cells, cancer-derived extracellular miR-122 is able to reprogram systemic energy metabolism to facilitate disease progression." other hsa-mir-551b Gastric Neoplasms 25623763 Expression of miR-551b-3p in gastric cancer cell lines and tissues and its clinical significance. other hsa-mir-21 Glioblastoma 25628933 Dox and miR-21 inhibitor therapy can sensitize GBM resistant cells to anthracyclines by enhancing apoptosis. other hsa-mir-451a Glioma 25629604 Effective control of growing cells near BV sites in addition to relocalization of invisible migratory cells back to the resection site was suggested as a way of eradicating these migratory cells. other hsa-mir-146a Rheumatoid Arthritis 25630616 "the miRNA-146 GG genotype might increase the risk of RA in females, and CC genotype may influence disease activity when evaluated with DAS28 score." other hsa-mir-181b Glioblastoma 25633526 NF-¦ÊB activation by DNA damage in GBM cells confers resistance to radiation-induced death. other hsa-mir-145 "Carcinoma, Endometrial" 25634023 "OCT4-pg5 can act as an RNA sponge to protect OCT4 transcripts from being inhibited by miR-145, providing novel insight into the control of OCT4 expression." other hsa-mir-29 Gastric Neoplasms 25634213 a global mechanism for understanding the efficacious effects of cytotoxic chemotherapy in gastric cancer. other hsa-let-7g Atypical Teratoid Tumor 25638158 LIN28A knockdown led to increased expression of let-7b and let-7g microRNAs and a down-regulation of KRAS mRNA. other hsa-mir-210 Gallstones 25639987 An integrated analysis of differential miRNA and mRNA expressions in human gallstones. other hsa-mir-1266 Breast Neoplasms 25640367 Association of miR-1266 with recurrence/metastasis potential in estrogen receptor positive breast cancer patients. other hsa-mir-221 "Carcinoma, Lung, Non-Small-Cell" 25641933 Growth inhibitory effects of miR-221 and miR-222 in non-small cell lung cancer cells. other hsa-mir-222 "Carcinoma, Lung, Non-Small-Cell" 25641933 Growth inhibitory effects of miR-221 and miR-222 in non-small cell lung cancer cells. other hsa-mir-484 Breast Neoplasms 25643696 Cytidine Deaminase Axis Modulated by miR-484 Differentially Regulates Cell Proliferation and Chemoresistance in Breast Cancer. other hsa-mir-206 Rhabdomyosarcoma 25644430 SMYD1 and G6PD modulation are critical events for miR-206-mediated differentiation of rhabdomyosarcoma. other hsa-mir-21 Cardiomegaly 25644540 miR-21: a star player in cardiac hypertrophy. other hsa-mir-200b Malignant Neoplasms [unspecific] 25644713 YY1 acts as novel critical interface between epigenetic code and miRNAs machinery under chronic hypoxia in malignancy. other hsa-mir-200c Malignant Neoplasms [unspecific] 25644713 YY1 acts as novel critical interface between epigenetic code and miRNAs machinery under chronic hypoxia in malignancy. other hsa-mir-3189 Glioblastoma 25645911 Anti-tumoral effects of miR-3189-3p in glioblastoma. other hsa-mir-155 Lymphoma 25645925 miR-155 controls the outcome of the GC reaction by modulating its initiation (Aicda) and termination (Socs1/p53 response) other hsa-mir-328 Lung Neoplasms 25646356 The predictive value and potential mechanisms of miRNA-328 and miRNA-378 for brain metastases in operable and advanced non-small-cell lung cancer. other hsa-mir-378 Lung Neoplasms 25646356 The predictive value and potential mechanisms of miRNA-328 and miRNA-378 for brain metastases in operable and advanced non-small-cell lung cancer. other hsa-mir-146a Gout 25646371 Role of miR-146a in regulation of the acute inflammatory response to monosodium urate crystals. other hsa-mir-188 "Leukemia, Myeloid" 25646775 Identification of let-7a-2-3p or/and miR-188-5p as prognostic biomarkers in cytogenetically normal acute myeloid leukemia. other hsa-mir-122 Hepatitis C Virus Infection 25646812 Circulating miRNA-122 levels are associated with hepatic necroinflammation and portal hypertension in HIV/HCV coinfection. other hsa-mir-34b Breast Neoplasms 25647415 The regulation and function of miR-21-FOXO3a-miR-34b/c signaling in breast cancer. other hsa-mir-34c Breast Neoplasms 25647415 The regulation and function of miR-21-FOXO3a-miR-34b/c signaling in breast cancer. other hsa-mir-206 Gastric Neoplasms 25653235 Activation of PAX3-MET pathways due to miR-206 loss promotes gastric cancer metastasis. other hsa-mir-30a "Carcinoma, Hepatocellular" 25654285 "Effect of miR-30a-5p on the proliferation, apoptosis, invasion and migration of SMCC-7721 human hepatocellular carcinoma cells" other hsa-mir-143 Vascular Disease [unspecific] 25655189 Myocyte Enhancer Factor 2A Regulates Hydrogen Peroxide-Induced Senescence of Vascular Smooth Muscle Cells Via microRNA-143. other hsa-mir-145 Vascular Disease [unspecific] 25655189 Myocyte Enhancer Factor 2A Regulates Hydrogen Peroxide-Induced Senescence of Vascular Smooth Muscle Cells Via microRNA-143. other hsa-mir-143 Gastric Neoplasms 25656032 Expression of miR-143 and miR-145 and their functional study in gastric carcinoma. other hsa-mir-145 Gastric Neoplasms 25656032 Expression of miR-143 and miR-145 and their functional study in gastric carcinoma. other hsa-mir-21 Multiple Myeloma 25656574 PSMB4 promotes multiple myeloma cell growth by activating NF-¦ÊB-miR-21 signaling. other hsa-mir-29a "Carcinoma, Breast" 25656908 Epigenetic Regulation of miR-29s Affects the Lactation Activity of Dairy Cow Mammary Epithelial Cells. other hsa-mir-29b "Carcinoma, Breast" 25656908 Epigenetic Regulation of miR-29s Affects the Lactation Activity of Dairy Cow Mammary Epithelial Cells. other hsa-mir-29c "Carcinoma, Breast" 25656908 Epigenetic Regulation of miR-29s Affects the Lactation Activity of Dairy Cow Mammary Epithelial Cells. other hsa-mir-21 Coronary Artery Disease 25656948 "MiR-34a, miR-21 and miR-23a as potential biomarkers for coronary artery disease: a pilot microarray study and confirmation in a 32 patient cohort." other hsa-mir-23a Coronary Artery Disease 25656948 "MiR-34a, miR-21 and miR-23a as potential biomarkers for coronary artery disease: a pilot microarray study" other hsa-mir-34a Coronary Artery Disease 25656948 "MiR-34a, miR-21 and miR-23a as potential biomarkers for coronary artery disease: a pilot microarray study and confirmation in a 32 patient cohort." other hsa-mir-101 Bladder Neoplasms 25658842 "miR-101 suppresses VEGF-C expression, inhibits cell migration and invasion, and increases cisplatin sensitivity in bladder cancer cells. " other hsa-mir-509 Breast Neoplasms 25659578 suppresses brain metastasis of breast cancer cells by modulating RhoC and TNF-¦Á. other hsa-mir-494 Preeclampsia 25660325 we report an unrecognized mechanism of miR-494 affecting dMSC proliferation and function in the pathology of PE. other hsa-mir-760 Breast Neoplasms 25661353 Systematic analysis of gene expression pattern in has-miR-760 overexpressed resistance of the MCF-7 human breast cancer cell to doxorubicin. other hsa-mir-592 Colorectal Carcinoma 25661360 Up-regulation of miR-592 correlates with tumor progression and poor prognosis in patients with colorectal cancer. other hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 25661374 Low miR-145 expression level is associated with poor pathological differentiation and poor prognosis in non-small cell lung cancer. other hsa-mir-122 Hepatitis C Virus Infection 25662750 miR-122 stimulates hepatitis C virus RNA synthesis by altering the balance of viral RNAs engaged in replication versus translation. other hsa-mir-494 Glioblastoma 25662849 "miR-494-3p Regulates Cellular Proliferation, Invasion, Migration, and Apoptosis by PTEN/AKT Signaling in Human Glioblastoma Cells." other hsa-mir-375 Breast Neoplasms 25663261 This study demonstrated that formononetin promoted ER¦Á-positive cell proliferation through miR-375 activation and this mechanism is possibly involving in a miR-375 and ER¦Á feedback loop. other hsa-mir-137 "Carcinoma, Gastric" 25663388 Epigenetic silencing of miR-137 is a frequent event in gastric carcinogenesis. other hsa-mir-423 Breast Neoplasms 25663458 Genetic analysis and preliminary function study of miR-423 in breast cancer. other hsa-mir-199a Cystic Fibrosis 25665524 Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation. other hsa-mir-15b Vascular Disease [unspecific] 25665638 "We focus on the diverse roles of miR-15b in the occurrence, progression and prognosis of vascular diseases,with particular emphasis on preeclampsia, a hypertensive disorder related to endovascular dysfunction in the placenta." other hsa-mir-31 Inflammatory Bowel Diseases 25665881 Differential expression of miR-31 between inflammatory bowel disease and microscopic colitis. other hsa-mir-155 Osteosarcoma 25666090 miR-155 promotes the growth of osteosarcoma in a HBP1-dependent mechanism. other hsa-mir-145 "Carcinoma, Cervical" 25666710 MicroRNA-145 contributes to enhancing radiosensitivity of cervical cancer cells. other hsa-let-7a "Carcinoma, Breast" 25669981 Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA. other hsa-mir-95 Colorectal Carcinoma 25671802 Glargine Promotes Human Colorectal Cancer Cell Proliferation via Upregulation of miR-95. other hsa-mir-155 Glioma 25672607 miR-155 contributes to the progression of glioma by enhancing Wnt/¦Â-catenin pathway. other hsa-mir-200c "Carcinoma, Gastric" 25672630 DZNep raises miR-200c expression to delay the invasion and migration of MGC-803 gastric carcinoma cells other hsa-mir-25 Neoplasms [unspecific] 25672882 miR-25 is suggested to be important in TNF-¦Á-induced abnormal proliferation of vascular smooth muscle cells (VSMCs). other hsa-mir-199a Hepatoblastoma 25673149 The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines. other hsa-mir-182 Urinary Bladder Cancer 25676538 This study shows that the level of miR-182 is higher in cytology specimens from high-grade UCC patients as compared to normal controls.Measuring miR-182 may provide a potential alternative or adjunct approach for screening high-grade UCC. other hsa-mir-17 Glioblastoma 25677619 Our findings suggest that engineering of tumor antigen-specific CD8(+) T-cells to express miR-17-92 may improve the potency of cancer immunotherapy. other hsa-mir-18 Glioblastoma 25677619 Our findings suggest that engineering of tumor antigen-specific CD8(+) T-cells to express miR-17-92 may improve the potency of cancer immunotherapy. other hsa-mir-19a Glioblastoma 25677619 Our findings suggest that engineering of tumor antigen-specific CD8(+) T-cells to express miR-17-92 may improve the potency of cancer immunotherapy. other hsa-mir-19b-1 Glioblastoma 25677619 Our findings suggest that engineering of tumor antigen-specific CD8(+) T-cells to express miR-17-92 may improve the potency of cancer immunotherapy. other hsa-mir-20a Glioblastoma 25677619 Our findings suggest that engineering of tumor antigen-specific CD8(+) T-cells to express miR-17-92 may improve the potency of cancer immunotherapy. other hsa-mir-92-1 Glioblastoma 25677619 Our findings suggest that engineering of tumor antigen-specific CD8(+) T-cells to express miR-17-92 may improve the potency of cancer immunotherapy. other hsa-mir-193b "Squamous Cell Carcinoma, Head and Neck" 25677760 Alteration in miR-193b expression level does not show any significant association with cancer survival. other hsa-mir-206 Muscle Diseases [unspecific] 25678853 "MiR-206, a key modulator of skeletal muscle development and disease." other hsa-mir-211 "Carcinoma, Breast, Triple Negative" 25680404 "MicroRNA-211, a direct negative regulator of CDC25B expression, inhibits triple-negative breast cancer cells' growth and migration." other hsa-mir-135a Breast Neoplasms 25680412 This study aimed to screen potential microRNAs (miRNAs) and genes related to human primary breast cancer. other hsa-mir-139 Breast Neoplasms 25680412 This study aimed to screen potential microRNAs (miRNAs) and genes related to human primary breast cancer. other hsa-mir-375 Breast Neoplasms 25680412 This study aimed to screen potential microRNAs (miRNAs) and genes related to human primary breast cancer. other hsa-mir-592 Breast Neoplasms 25680412 This study aimed to screen potential microRNAs (miRNAs) and genes related to human primary breast cancer. other hsa-mir-9 Breast Neoplasms 25680412 This study aimed to screen potential microRNAs (miRNAs) and genes related to human primary breast cancer. other hsa-mir-603 Glioma 25681036 miR-603 promotes glioma cell growth via Wnt/¦Â-catenin pathway by inhibiting WIF1 and CTNNBIP1. other hsa-mir-130a Pulmonary Hypertension 25681685 These data suggest that miRNA family miR-130 plays an important role in the repression of CDKN1A by hypoxia.miR-130 enhances hypoxia-induced smooth muscle proliferation and might be involved in the development of right ventricular hypertrophy and vascular remodeling in pulmonary hypertension. other hsa-mir-31 Wounds and Injuries [unspecific] 25685928 MicroRNA-31 Promotes Skin Wound Healing by Enhancing Keratinocyte Proliferation and Migration. other hsa-mir-455 Melanoma 25686251 Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis. other hsa-mir-512 "Carcinoma, Lung, Non-Small-Cell" 25687035 Inhibition of RAC1-GEF DOCK3 by miR-512-3p contributes to suppression of metastasis in non-small cell lung cancer. other hsa-mir-21 Vascular Hypertrophy 25689721 Ursolic acid down-regulated miRNA-21 expression and up-regulated PTEN protein and mRNA expression. other hsa-mir-30 Muscle Diseases [unspecific] 25689854 These findings indicate that the miR-30 family may be an interesting biomarker of perturbed muscle homeostasis and muscle disease. other hsa-mir-150 Immune System Disease [unspecific] 25690461 Our current studies characterized TsF as regulatory miRNA-150 carried by T suppressor cell-derived exosomes that are antigen specific due to a surface coat of IgM antibody light chains produced by B1a cells. other hsa-mir-139 Neoplasms [unspecific] 25691250 MiR-139-5p: promising biomarker for cancer. other hsa-mir-205 Lung Neoplasms 25695220 MiR-205 and MiR-375 microRNA assays to distinguish squamous cell carcinoma from adenocarcinoma in lung cancer biopsies. other hsa-mir-375 Lung Neoplasms 25695220 MiR-205 and MiR-375 microRNA assays to distinguish squamous cell carcinoma from adenocarcinoma in lung cancer biopsies. other hsa-mir-663 Alzheimer Disease 25695604 Our results indicate that AICD has a novel role in suppression of neuronal differentiation via transcriptional regulation of miR-663 in human neural stem cells. other hsa-mir-27b Liver Neoplasms 25698578 we propose that miR-27b synergizes with anticancer drugs in a defined subgroup of liver and kidney cancer patients. other hsa-mir-155 Keratitis 25700796 Role of miR-155 in the pathogenesis of herpetic stromal keratitis. other hsa-mir-185 "Carcinoma, Renal Cell, Clear-Cell" 25700976 "Our results suggest that the miR-185, as a tumor suppressor, plays a pivotal role by inhibiting VEGFA in VHL-inactivated ccRCC." other hsa-mir-126 Obesity 25701361 Our study provides a bioinformatic basis for further research of molecular mechanism in obesity. other hsa-mir-16 Obesity 25701361 Our study provides a bioinformatic basis for further research of molecular mechanism in obesity. other hsa-mir-425 Obesity 25701361 Our study provides a bioinformatic basis for further research of molecular mechanism in obesity. other hsa-mir-634 Obesity 25701361 Our study provides a bioinformatic basis for further research of molecular mechanism in obesity. other hsa-mir-143 "Carcinoma, Nasopharyngeal" 25701793 Identification of miR-143 as a tumour suppressor in nasopharyngeal carcinoma based on microRNA expression profiling. other hsa-mir-100 Gastric Neoplasms 25703026 The role of miR-100-mediated Notch pathway in apoptosis of gastric tumor cells. other hsa-let-7d Obesity 25704235 Nonivamide enhances miRNA let-7d expression and decreases adipogenesis PPARγ expression in 3T3-L1 cells. other hsa-mir-708 "Leukemia, Lymphocytic, Chronic, B-Cell" 25704289 Epigenetic silencing of miR-708 enhances NF-¦ÊB signaling in chronic lymphocytic leukemia. other hsa-mir-128 "Carcinoma, Hepatocellular" 25704921 Suppression of CYP2C9 by microRNA hsa-miR-128-3p in human liver cells and association with hepatocellular carcinoma. other hsa-mir-31 Liver Injury 25706292 "Both compounds also down-regulated miR-31, which directly targets caspase-2 and influences apoptosis in SEB-activated cells." other hsa-mir-199a Atrial Fibrillation 25706326 Our combined transcriptomic analysis and miRNA microarray study of atrial samples from pAF patients revealed novel pathways and miRNA-mRNA regulations that may be relevant in the development of pAF. Future studies are required to investigate the potential involvement of the gonadotropin releasing hormone receptor and p53 pathways in AF pathogenesis. other hsa-mir-21 Breast Neoplasms 25706383 "Our results indicated that miR-21 can predict unfavorable prognoses in breast cancer patients, especially in Asians." other hsa-mir-17 Hepatitis C Virus Infection 25707620 Our rule discovery method is useful for integrating binding information and expression profile for identifying HCV miRNA-mRNA regulatory modules and can be applied to the study of the expression profiles of other complex human diseases. other hsa-mir-557 Hepatitis C Virus Infection 25707620 Our rule discovery method is useful for integrating binding information and expression profile for identifying HCV miRNA-mRNA regulatory modules and can be applied to the study of the expression profiles of other complex human diseases. other hsa-mir-765 Hepatitis C Virus Infection 25707620 Our rule discovery method is useful for integrating binding information and expression profile for identifying HCV miRNA-mRNA regulatory modules and can be applied to the study of the expression profiles of other complex human diseases. other hsa-mir-153 "Carcinoma, Hepatocellular" 25708809 MicroRNA-153 promotes Wnt/¦Â-catenin activation in hepatocellular carcinoma through suppression of WWOX. other hsa-mir-223 "Leukemia, Myeloid, Acute" 25710580 De Novo Acute Myeloid Leukemia in Adults: Suppression of MicroRNA-223 is Independent of LMO2 Protein Expression BUT Associate With Adverse Cytogenetic Profile and Undifferentiated Blast Morphology. other hsa-let-7f Obesity 25710930 "genes modulated in RO-treated cells were found to be validated miRNAs targets, such as let-7f-1, miR-17, and miR-143." other hsa-mir-27a Colorectal Carcinoma 25712055 Novel Evidence for Curcumin and Boswellic Acid-Induced Chemoprevention through Regulation of miR-34a and miR-27a in Colorectal Cancer. other hsa-mir-34a Colorectal Carcinoma 25712055 Novel Evidence for Curcumin and Boswellic Acid-Induced Chemoprevention through Regulation of miR-34a and miR-27a in Colorectal Cancer. other hsa-mir-335 "Carcinoma, Cervical" 25712373 MicroRNA-335 represents an independent prognostic marker in cervical cancer. other hsa-mir-30a "Carcinoma, Renal Cell" 25712526 MiRNA-30a-mediated autophagy inhibition sensitizes renal cell carcinoma cells to sorafenib. other hsa-mir-199a "Carcinoma, Hepatocellular" 25714015 "Increase of miR-199a-5p by protoporphyrin IX, a photocatalyzer, directly inhibits E2F3, sensitizing mesenchymal tumor cells to anti-cancer agents." other hsa-mir-372 "Squamous Cell Carcinoma, Head and Neck" 25714028 miR-372 inhibits p62 in head and neck squamous cell carcinoma in vitro and in vivo. other hsa-mir-148a Adenovirus Infection 25714032 "Thus, miRNA-control of late proteins constitutes a novel strategy to provide selectivity to adenoviruses." other hsa-let-7 "Carcinoma, Lung, Non-Small-Cell" 25714397 Combinatorial Action of MicroRNAs let-7 and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation. other hsa-mir-34 "Carcinoma, Lung, Non-Small-Cell" 25714397 Combinatorial Action of MicroRNAs let-7 and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation. other hsa-mir-133a "Carcinoma, Hepatocellular" 25714665 These findings for the first time demonstrated that the involvement of miR-133a and miR-326 in MDR is mediated by ABCC1 in hepatocellular carcinoma cell line HepG2 and suggested that miR-133a and miR-326 may be efficient agents for preventing and reversing ADM resistance in cancer cells. other hsa-mir-326 "Carcinoma, Hepatocellular" 25714665 These findings for the first time demonstrated that the involvement of miR-133a and miR-326 in MDR is mediated by ABCC1 in hepatocellular carcinoma cell line HepG2 and suggested that miR-133a and miR-326 may be efficient agents for preventing and reversing ADM resistance in cancer cells. other hsa-mir-424 Neoplasms [unspecific] 25716682 TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation. other hsa-mir-27a Liver Diseases [unspecific] 25716995 our study demonstrates the regulatory role of miR-27a in alcohol-induced monocyte activation and polarization. other hsa-let-7c Human Immunodeficiency Virus Infection 25717002 "Our data suggest that HIV-1 exploits the host miRNA cellular systems in order to block the innate inhibition mechanism, allowing a more efficient infection process." other hsa-mir-124a Human Immunodeficiency Virus Infection 25717002 "Our data suggest that HIV-1 exploits the host miRNA cellular systems in order to block the innate inhibition mechanism, allowing a more efficient infection process." other hsa-mir-34a Human Immunodeficiency Virus Infection 25717002 "Our data suggest that HIV-1 exploits the host miRNA cellular systems in order to block the innate inhibition mechanism, allowing a more efficient infection process." other hsa-mir-21 "Carcinoma, Hepatocellular" 25720799 High-Mobility Group Box 1 Promotes Hepatocellular Carcinoma Progression through miR-21-Mediated Matrix Metalloproteinase Activity. other hsa-let-7a Breast Neoplasms 25722304 These results point to using high levels of tRNA-derived small RNA fragments in combination with known miR signatures of tumors to distinguish tumor-derived EVs in circulation from EVs derived from other cell sources. Such biomarkers would be unique to the EVs where high abundances of tRNA fragments are amplified with respect to their cellular levels. other hsa-mir-125b Breast Neoplasms 25722304 These results point to using high levels of tRNA-derived small RNA fragments in combination with known miR signatures of tumors to distinguish tumor-derived EVs in circulation from EVs derived from other cell sources. Such biomarkers would be unique to the EVs where high abundances of tRNA fragments are amplified with respect to their cellular levels. other hsa-mir-1274b Breast Neoplasms 25722304 These results point to using high levels of tRNA-derived small RNA fragments in combination with known miR signatures of tumors to distinguish tumor-derived EVs in circulation from EVs derived from other cell sources. Such biomarkers would be unique to the EVs where high abundances of tRNA fragments are amplified with respect to their cellular levels. other hsa-mir-205 Breast Neoplasms 25722304 These results point to using high levels of tRNA-derived small RNA fragments in combination with known miR signatures of tumors to distinguish tumor-derived EVs in circulation from EVs derived from other cell sources. Such biomarkers would be unique to the EVs where high abundances of tRNA fragments are amplified with respect to their cellular levels. other hsa-mir-21 Breast Neoplasms 25722304 These results point to using high levels of tRNA-derived small RNA fragments in combination with known miR signatures of tumors to distinguish tumor-derived EVs in circulation from EVs derived from other cell sources. Such biomarkers would be unique to the EVs where high abundances of tRNA fragments are amplified with respect to their cellular levels. other hsa-mir-720 Breast Neoplasms 25722304 These results point to using high levels of tRNA-derived small RNA fragments in combination with known miR signatures of tumors to distinguish tumor-derived EVs in circulation from EVs derived from other cell sources. Such biomarkers would be unique to the EVs where high abundances of tRNA fragments are amplified with respect to their cellular levels. other hsa-mir-630 "Carcinoma, Hepatocellular" 25731670 These results suggest that miR-630 is associated with tumor progression of hepatocellular carcinoma and may be a potential prognosis indicator. other hsa-mir-526b Breast Neoplasms 25733698 COX-2 Elevates Oncogenic miR-526b in Breast Cancer by EP4 Activation. other hsa-mir-324 "Carcinoma, Nasopharyngeal" 25735100 The loss of miRNA-324-3p and ectopic WNT2B might co-induce the initiation and progression of NPC. other hsa-mir-222 Breast Neoplasms 25735339 Ginsenoside Rh2 differentially mediates microRNA expression to prevent chemoresistance of breast cancer. other hsa-mir-29a Breast Neoplasms 25735339 Ginsenoside Rh2 differentially mediates microRNA expression to prevent chemoresistance of breast cancer. other hsa-mir-34a Breast Neoplasms 25735339 Ginsenoside Rh2 differentially mediates microRNA expression to prevent chemoresistance of breast cancer. other hsa-mir-21 Breast Neoplasms 25735723 MiR-21 controls in situ expansion of CCR6 regulatory T cells through PTEN/AKT pathway in breast cancer. other hsa-mir-205 Glioblastoma 25736407 Pterostilbene suppressed irradiation-resistant glioma stem cells by modulating GRP78/miR-205 axis. other hsa-mir-24 "Diabetes Mellitus, Type 2" 25737017 Pioglitazone increases circulating microRNA-24 with decrease in coronary neointimal hyperplasia in type 2 diabetic patients- optical coherence tomography analysis. other hsa-mir-29b Uterine Corpus Choriocarcinoma 25738313 BAG3 increases the invasiveness of uterine corpus carcinoma cells by suppressing miR-29b and enhancing MMP2 expression. other hsa-mir-10b Glioblastoma 25738367 MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma. other hsa-mir-15 Glioblastoma 25738367 MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma. other hsa-mir-16 Glioblastoma 25738367 MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma. other hsa-mir-182 "Carcinoma, Hepatocellular" 25739014 "A pleiotropic effect of the single clustered hepatic metastamiRs miR-96-5p and miR-182-5p on insulin-like growth factor II, insulin-like growth factor-1 receptor and insulin-like growth factor-binding protein-3 in hepatocellular carcinoma." other hsa-mir-133a Arteriosclerosis Obliterans 25740337 MicroRNA-133a in the Development of Arteriosclerosis Obliterans. other hsa-mir-216b "Carcinoma, Hepatocellular" 25741595 MiR-216b is involved in pathogenesis and progression of hepatocellular carcinoma through HBx-miR-216b-IGF2BP2 signaling pathway. other hsa-mir-186 "Adenocarcinoma, Pancreatic Ductal" 25742499 miR-186 and 326 predict the prognosis of pancreatic ductal adenocarcinoma and affect the proliferation and migration of cancer cells. other hsa-mir-326 "Adenocarcinoma, Pancreatic Ductal" 25742499 miR-186 and 326 predict the prognosis of pancreatic ductal adenocarcinoma and affect the proliferation and migration of cancer cells. other hsa-mir-155 Breast Neoplasms 25744731 Role of miR-155 in drug resistance of breast cancer. other hsa-mir-33a Lipid Metabolism Disorder 25744742 "we describe the current understanding of the function of miR-33a/b in lipid homeostasis, focusing on the thrifty aspect." other hsa-mir-33b Lipid Metabolism Disorder 25744742 "we describe the current understanding of the function of miR-33a/b in lipid homeostasis, focusing on the thrifty aspect." other hsa-mir-200c Breast Neoplasms 25746005 "Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential." other hsa-mir-1270 Inflammation 25746225 This coordinated regulatory architecture suggests a vital function for the innate immune system in maintaining precise physiological type I IFN levels via post-transcriptional regulatory mechanisms. other hsa-mir-141 "Squamous Cell Carcinoma, Lung" 25746592 MicroRNA-141 is a biomarker for progression of squamous cell carcinoma and adenocarcinoma of the lung: clinical analysis of 125 patients. other hsa-mir-29a "Lymphoma, Burkitt" 25746661 "Deregulation of DNMT1, DNMT3B and miR-29s in Burkitt lymphoma suggests novel contribution for disease pathogenesis." other hsa-mir-29b "Lymphoma, Burkitt" 25746661 "Deregulation of DNMT1, DNMT3B and miR-29s in Burkitt lymphoma suggests novel contribution for disease pathogenesis." other hsa-mir-29c "Lymphoma, Burkitt" 25746661 "Deregulation of DNMT1, DNMT3B and miR-29s in Burkitt lymphoma suggests novel contribution for disease pathogenesis." other hsa-mir-17 "Carcinoma, Thyroid, Follicular" 25748447 Sphingosine-1-phosphate induces the migration of thyroid follicular carcinoma cells through the microRNA-17/PTK6/ERK1/2 pathway. other hsa-mir-27a Osteosarcoma 25749032 miR-27a and miR-27a* contribute to metastatic properties of osteosarcoma cells. other hsa-mir-16 Prostate Neoplasms 25750034 This study highlights that commonly used endogenous controls can be responsive to radiation and validation is required prior to gene/miRNAs expression studies. other hsa-mir-331 "Carcinoma, Hepatocellular" 25750939 This provided useful information in exploring the mechanism of HCC induced by HBV infection. other hsa-mir-204 "Carcinoma, Nasopharyngeal" 25752113 Clinical significance of miRNA-204 in nasopharyngeal carcinoma. other hsa-mir-124 Glioblastoma 25753094 Gap Junctions Enhance the Antiproliferative Effect of MicroRNA-124-3p in Glioblastoma Cells. other hsa-mir-223 Hematologic Neoplasms 25753223 "C/EBPα interacts with AP-1 proteins to bind hybrid DNA elements during monopoiesis, and induction of Gfi-1, C/EBPε, KLF5, and miR-223 by C/EBPα enables granulopoiesis." other hsa-mir-142 Endometrial Stromal Sarcoma 25754227 miR-142-3p is a novel regulator of cell viability and proinflammatory signalling in endometrial stroma cells. other hsa-mir-1179 "Squamous Cell Carcinoma, Esophageal" 25755718 miR-1179 promotes cell invasion through SLIT2/ROBO1 axis in esophageal squamous cell carcinoma. other hsa-mir-18a "Carcinoma, Lung, Non-Small-Cell" 25755757 Effect of miR-18a overexpression on the radiosensitivity of non-small cell lung cancer. other hsa-let-7a Pleural Mesothelioma 25756049 Specific microRNAs and mRNAs may have diagnostic utility in differentiating patients with malignant pleural mesothelioma from benign asbestos-related pleural effusion. These studies may be particularly helpful in patients who reside in a region with a high incidence of mesothelioma. other hsa-mir-125a Pleural Mesothelioma 25756049 Specific microRNAs and mRNAs may have diagnostic utility in differentiating patients with malignant pleural mesothelioma from benign asbestos-related pleural effusion. These studies may be particularly helpful in patients who reside in a region with a high incidence of mesothelioma. other hsa-mir-320 Pleural Mesothelioma 25756049 Specific microRNAs and mRNAs may have diagnostic utility in differentiating patients with malignant pleural mesothelioma from benign asbestos-related pleural effusion. These studies may be particularly helpful in patients who reside in a region with a high incidence of mesothelioma. other hsa-mir-484 Pleural Mesothelioma 25756049 Specific microRNAs and mRNAs may have diagnostic utility in differentiating patients with malignant pleural mesothelioma from benign asbestos-related pleural effusion. These studies may be particularly helpful in patients who reside in a region with a high incidence of mesothelioma. other hsa-mir-1204 "Carcinoma, Nasopharyngeal" 25756509 MiR-1204 sensitizes nasopharyngeal carcinoma cells to paclitaxel both in vitro and in vivo. other hsa-let-7a Alzheimer Disease 25759134 "we demonstrate in detail the power of DNA/RNA chimera/AgNC probes in detecting two human miRNAs,let-7a and miR-200c. The DNA/RNA chimera-based probes are highly efficient to determine the level of miRNAs in several human cell lines." other hsa-let-7a Asthma 25759134 "we demonstrate in detail the power of DNA/RNA chimera/AgNC probes in detecting two human miRNAs,let-7a and miR-200c. The DNA/RNA chimera-based probes are highly efficient to determine the level of miRNAs in several human cell lines." other hsa-let-7a Autoimmune Diseases [unspecific] 25759134 "we demonstrate in detail the power of DNA/RNA chimera/AgNC probes in detecting two human miRNAs,let-7a and miR-200c. The DNA/RNA chimera-based probes are highly efficient to determine the level of miRNAs in several human cell lines." other hsa-let-7a Cardiovascular Diseases [unspecific] 25759134 "we demonstrate in detail the power of DNA/RNA chimera/AgNC probes in detecting two human miRNAs,let-7a and miR-200c. The DNA/RNA chimera-based probes are highly efficient to determine the level of miRNAs in several human cell lines." other hsa-let-7a Diabetes Mellitus 25759134 "we demonstrate in detail the power of DNA/RNA chimera/AgNC probes in detecting two human miRNAs,let-7a and miR-200c. The DNA/RNA chimera-based probes are highly efficient to determine the level of miRNAs in several human cell lines." other hsa-let-7a Neoplasms [unspecific] 25759134 "we demonstrate in detail the power of DNA/RNA chimera/AgNC probes in detecting two human miRNAs,let-7a and miR-200c. The DNA/RNA chimera-based probes are highly efficient to determine the level of miRNAs in several human cell lines." other hsa-mir-200c Alzheimer Disease 25759134 "we demonstrate in detail the power of DNA/RNA chimera/AgNC probes in detecting two human miRNAs,let-7a and miR-200c. The DNA/RNA chimera-based probes are highly efficient to determine the level of miRNAs in several human cell lines." other hsa-mir-200c Asthma 25759134 "we demonstrate in detail the power of DNA/RNA chimera/AgNC probes in detecting two human miRNAs,let-7a and miR-200c. The DNA/RNA chimera-based probes are highly efficient to determine the level of miRNAs in several human cell lines." other hsa-mir-200c Autoimmune Diseases [unspecific] 25759134 "we demonstrate in detail the power of DNA/RNA chimera/AgNC probes in detecting two human miRNAs,let-7a and miR-200c. The DNA/RNA chimera-based probes are highly efficient to determine the level of miRNAs in several human cell lines." other hsa-mir-200c Cardiovascular Diseases [unspecific] 25759134 "we demonstrate in detail the power of DNA/RNA chimera/AgNC probes in detecting two human miRNAs,let-7a and miR-200c. The DNA/RNA chimera-based probes are highly efficient to determine the level of miRNAs in several human cell lines." other hsa-mir-200c Diabetes Mellitus 25759134 "we demonstrate in detail the power of DNA/RNA chimera/AgNC probes in detecting two human miRNAs,let-7a and miR-200c. The DNA/RNA chimera-based probes are highly efficient to determine the level of miRNAs in several human cell lines." other hsa-mir-200c Neoplasms [unspecific] 25759134 "we demonstrate in detail the power of DNA/RNA chimera/AgNC probes in detecting two human miRNAs,let-7a and miR-200c. The DNA/RNA chimera-based probes are highly efficient to determine the level of miRNAs in several human cell lines." other hsa-mir-106a "Carcinoma, Hepatocellular" 25760076 The PDGF-D/miR-106a/Twist1 pathway orchestrates epithelial-mesenchymal transition in gemcitabine resistance hepatoma cells. other hsa-mir-449a Neoplasms [unspecific] 25760387 microRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrest. other hsa-mir-155 Atopic Dermatitis 25761610 MicroRNA-155 may be involved in the pathogenesis of atopic dermatitis by modulating the differentiation and function of T helper type 17 (Th17) cells. other hsa-mir-34a "Squamous Cell Carcinoma, Head and Neck" 25762634 MiR-34a suppresses amphiregulin and tumor metastatic potential of head and neck squamous cell carcinoma (HNSCC). other hsa-mir-125b Heart Failure 25763857 "Measured microRNA profiles did not separate the samples according to the clinical features of the patients. However, several previously identified heart failure marker microRNAs were detected. The pericardial fluid microRNA profile appeared to be a result of an active and selective secretory process indicating that microRNAs may act as paracrine signalling factors by mediating the local crosstalk between cardiac cells." other hsa-mir-16 Heart Failure 25763857 "Measured microRNA profiles did not separate the samples according to the clinical features of the patients. However, several previously identified heart failure marker microRNAs were detected. The pericardial fluid microRNA profile appeared to be a result of an active and selective secretory process indicating that microRNAs may act as paracrine signalling factors by mediating the local crosstalk between cardiac cells." other hsa-mir-21 Heart Failure 25763857 "Measured microRNA profiles did not separate the samples according to the clinical features of the patients. However, several previously identified heart failure marker microRNAs were detected. The pericardial fluid microRNA profile appeared to be a result of an active and selective secretory process indicating that microRNAs may act as paracrine signalling factors by mediating the local crosstalk between cardiac cells." other hsa-mir-451a Heart Failure 25763857 "Measured microRNA profiles did not separate the samples according to the clinical features of the patients. However, several previously identified heart failure marker microRNAs were detected. The pericardial fluid microRNA profile appeared to be a result of an active and selective secretory process indicating that microRNAs may act as paracrine signalling factors by mediating the local crosstalk between cardiac cells." other hsa-mir-128 "Squamous Cell Carcinoma, Head and Neck" 25764126 Functions of MiRNA-128 on the regulation of head and neck squamous cell carcinoma growth and apoptosis. other hsa-mir-577 Glioblastoma 25764520 miR-577 inhibits glioblastoma tumor growth via the Wnt signaling pathway. other hsa-mir-19b Atherosclerosis 25765596 The present study demonstrates that Dgn enhances ABCA1-dependent cholesterol efflux and inhibits aortic atherosclerosis progression by suppressing macrophage miR-19b expression. other hsa-mir-23b Gastric Neoplasms 25765901 Reciprocal repression between TUSC7 and miR-23b in gastric cancer. other hsa-mir-122 Hepatitis C Virus Infection 25768906 Hepatitis C virus RNA functionally sequesters miR-122. other hsa-mir-33a Obesity 25769350 "Deregulation of miR-33 and miR-122, as major regulators of lipid metabolism in liver, has been related to obesity and metabolic syndrome." other hsa-mir-338 Kideny Transplant Rejection 25769569 miR-338-5p is closely correlated with the procedure of renal allograft antibody-mediated rejection. other hsa-mir-125b "Carcinoma, Lung, Non-Small-Cell" 25772251 Matrix metalloproteinase 13: a potential intermediate between low expression of microRNA-125b and increasing metastatic potential of non-small cell lung cancer. other hsa-mir-27a "Carcinoma, Lung, Non-Small-Cell" 25773791 Rs895819 within miR-27a might be involved in development of non small cell lung cancer in the Chinese Han population. other hsa-mir-143 "Carcinoma, Renal Cell, Clear-Cell" 25776476 our data support the notion that sunitinib and everolimus are able to directly induce cell death in renal cancer cells and simultaneously affect the expression levels of their apoptosis-related microRNAs and BCL2 family members upon this process. other hsa-mir-145 "Carcinoma, Renal Cell, Clear-Cell" 25776476 our data support the notion that sunitinib and everolimus are able to directly induce cell death in renal cancer cells and simultaneously affect the expression levels of their apoptosis-related microRNAs and BCL2 family members upon this process. other hsa-mir-15a "Carcinoma, Renal Cell, Clear-Cell" 25776476 our data support the notion that sunitinib and everolimus are able to directly induce cell death in renal cancer cells and simultaneously affect the expression levels of their apoptosis-related microRNAs and BCL2 family members upon this process. other hsa-mir-16 "Carcinoma, Renal Cell, Clear-Cell" 25776476 our data support the notion that sunitinib and everolimus are able to directly induce cell death in renal cancer cells and simultaneously affect the expression levels of their apoptosis-related microRNAs and BCL2 family members upon this process. other hsa-mir-182 "Carcinoma, Renal Cell, Clear-Cell" 25776476 our data support the notion that sunitinib and everolimus are able to directly induce cell death in renal cancer cells and simultaneously affect the expression levels of their apoptosis-related microRNAs and BCL2 family members upon this process. other hsa-mir-183 "Carcinoma, Renal Cell, Clear-Cell" 25776476 our data support the notion that sunitinib and everolimus are able to directly induce cell death in renal cancer cells and simultaneously affect the expression levels of their apoptosis-related microRNAs and BCL2 family members upon this process. other hsa-mir-96 "Carcinoma, Renal Cell, Clear-Cell" 25776476 our data support the notion that sunitinib and everolimus are able to directly induce cell death in renal cancer cells and simultaneously affect the expression levels of their apoptosis-related microRNAs and BCL2 family members upon this process. other hsa-mir-150 Prostate Neoplasms 25778313 miR-150 is a factor of survival in prostate cancer patients. other hsa-mir-125a Androgenetic Alopecia 25778683 "These results demonstrated that the expression of miRNA was altered in the DHT-treated nHDPCs and suggest the potential mechanisms of DHT-induced cell growth repression, cell cycle arrest, cell death, senescence and induction of ROS." other hsa-mir-485 Androgenetic Alopecia 25778683 "These results demonstrated that the expression of miRNA was altered in the DHT-treated nHDPCs and suggest the potential mechanisms of DHT-induced cell growth repression, cell cycle arrest, cell death, senescence and induction of ROS." other hsa-mir-7 Androgenetic Alopecia 25778683 "These results demonstrated that the expression of miRNA was altered in the DHT-treated nHDPCs and suggest the potential mechanisms of DHT-induced cell growth repression, cell cycle arrest, cell death, senescence and induction of ROS." other hsa-let-7b Neuroblastoma 25779425 Enterovirus 71 induces apoptosis of SH-SY5Y human neuroblastoma cells through stimulation of endogenous microRNA let-7b expression. other hsa-mir-133a Gastric Neoplasms 25780292 Tumor suppressor role of miR-133a in gastric cancer by repressing IGF1R. other hsa-mir-494 Neoplasms [unspecific] 25781916 "Specifically we have linked miR-134, miR-145, miR-146b-5p, miR-432 and miR-494 to the regulation of both apoptotic and anti-apoptotic genes expressed as a function of EGF treatment." other hsa-mir-21 Breast Neoplasms 25784176 "3,6-Dihydroxyflavone Suppresses Breast Carcinogenesis by Epigenetically Regulating miR-34a and miR-21." other hsa-mir-34a Breast Neoplasms 25784176 "3,6-Dihydroxyflavone Suppresses Breast Carcinogenesis by Epigenetically Regulating miR-34a and miR-21." other hsa-mir-218-1 Hirschsprung Disease 25786906 SLIT2/ROBO1-miR-218-1-RET/PLAG1: a new disease pathway involved in Hirschsprung's disease. other hsa-mir-16 Neoplasms [unspecific] 25787082 "In addition, we observed significantly reduced expression of microRNAs (miRNAs) including miR-16 and miR-19b, which are known to be significantly reduced in the semen of infertile men." other hsa-mir-122 Chronic Hepatitis B 25788377 Clinical significance of circulating miR-122 in patients with dual chronic hepatitis B and C virus infection. other hsa-let-7b Influenza 25788763 This approach provides an additional layer of biosafety and thus has great potential for the application in the rational development of safer and more effective influenza viral vaccines. other hsa-mir-200a Liver Injury 25789565 our data indicate that the p53-dependent expression of miR-200a-3p promotes cell death by inhibiting a p38/p53/miR-200 feedback loop. other hsa-mir-34a Breast Neoplasms 25789847 "Phytochemical regulation of the tumor suppressive microRNA, miR-34a, by p53-dependent and independent responses in human breast cancer cells." other hsa-mir-205 "Carcinoma, Breast, Triple Negative" 25792283 Pterostilbene inhibits triple-negative breast cancer metastasis via inducing microRNA-205 expression and negatively modulates epithelial-to-mesenchymal transition. other hsa-mir-486 "Adenocarcinoma, Gastric" 25793394 Expression and prognostic value of miR-486-5p in patients with gastric adenocarcinoma. other hsa-mir-221 Ischemic Diseases [unspecific] 25796380 "Moreover, exosomes from MSCs and MSCs treated by BYHWD induced elevated microRNA (miRNA)-126 expression and reduced miR-221 and miR-222 expression." other hsa-mir-222 Ischemic Diseases [unspecific] 25796380 "Moreover, exosomes from MSCs and MSCs treated by BYHWD induced elevated microRNA (miRNA)-126 expression and reduced miR-221 and miR-222 expression." other hsa-mir-150 "Leukemia, Lymphoblastic, Acute" 25796601 "This study not only identifies differences in the pathways and networks of acute lymphocytic leukemia (ALL) relative to normal lymphocytes, but also identifies unique functional characteristics of lymphoid cells and distinct gene expression patterns during lymphoid development. The discovery of leukemia-related miRNAs may provide meaningful insights into the biology of the disease." other hsa-mir-17 "Leukemia, Lymphoblastic, Acute" 25796601 "This study not only identifies differences in the pathways and networks of acute lymphocytic leukemia (ALL) relative to normal lymphocytes, but also identifies unique functional characteristics of lymphoid cells and distinct gene expression patterns during lymphoid development. The discovery of leukemia-related miRNAs may provide meaningful insights into the biology of the disease." other hsa-mir-18 "Leukemia, Lymphoblastic, Acute" 25796601 "This study not only identifies differences in the pathways and networks of acute lymphocytic leukemia (ALL) relative to normal lymphocytes, but also identifies unique functional characteristics of lymphoid cells and distinct gene expression patterns during lymphoid development. The discovery of leukemia-related miRNAs may provide meaningful insights into the biology of the disease." other hsa-mir-18a "Leukemia, Lymphoblastic, Acute" 25796601 "This study not only identifies differences in the pathways and networks of acute lymphocytic leukemia (ALL) relative to normal lymphocytes, but also identifies unique functional characteristics of lymphoid cells and distinct gene expression patterns during lymphoid development. The discovery of leukemia-related miRNAs may provide meaningful insights into the biology of the disease." other hsa-mir-19a "Leukemia, Lymphoblastic, Acute" 25796601 "This study not only identifies differences in the pathways and networks of acute lymphocytic leukemia (ALL) relative to normal lymphocytes, but also identifies unique functional characteristics of lymphoid cells and distinct gene expression patterns during lymphoid development. The discovery of leukemia-related miRNAs may provide meaningful insights into the biology of the disease." other hsa-mir-19b-1 "Leukemia, Lymphoblastic, Acute" 25796601 "This study not only identifies differences in the pathways and networks of acute lymphocytic leukemia (ALL) relative to normal lymphocytes, but also identifies unique functional characteristics of lymphoid cells and distinct gene expression patterns during lymphoid development. The discovery of leukemia-related miRNAs may provide meaningful insights into the biology of the disease." other hsa-mir-20a "Leukemia, Lymphoblastic, Acute" 25796601 "This study not only identifies differences in the pathways and networks of acute lymphocytic leukemia (ALL) relative to normal lymphocytes, but also identifies unique functional characteristics of lymphoid cells and distinct gene expression patterns during lymphoid development. The discovery of leukemia-related miRNAs may provide meaningful insights into the biology of the disease." other hsa-mir-222 "Leukemia, Lymphoblastic, Acute" 25796601 "This study not only identifies differences in the pathways and networks of acute lymphocytic leukemia (ALL) relative to normal lymphocytes, but also identifies unique functional characteristics of lymphoid cells and distinct gene expression patterns during lymphoid development. The discovery of leukemia-related miRNAs may provide meaningful insights into the biology of the disease." other hsa-mir-92-1 "Leukemia, Lymphoblastic, Acute" 25796601 "This study not only identifies differences in the pathways and networks of acute lymphocytic leukemia (ALL) relative to normal lymphocytes, but also identifies unique functional characteristics of lymphoid cells and distinct gene expression patterns during lymphoid development. The discovery of leukemia-related miRNAs may provide meaningful insights into the biology of the disease." other hsa-mir-92a "Leukemia, Lymphoblastic, Acute" 25796601 "This study not only identifies differences in the pathways and networks of acute lymphocytic leukemia (ALL) relative to normal lymphocytes, but also identifies unique functional characteristics of lymphoid cells and distinct gene expression patterns during lymphoid development. The discovery of leukemia-related miRNAs may provide meaningful insights into the biology of the disease." other hsa-mir-200a "Carcinoma, Hepatocellular" 25797260 MicroRNA-200a suppresses metastatic potential of side population cells in human hepatocellular carcinoma by decreasing ZEB2. other hsa-mir-432 "Carcinoma, Hepatocellular" 25797263 Downregulation of miR-432 activates Wnt/¦Â-catenin signaling and promotes human hepatocellular carcinoma proliferation. other hsa-let-7e Cystic Fibrosis 25800681 "Ingenuity Pathway Analysis indicated that hsa-miR-99b and hsa-miR-125a could be associated with the phenotypes manifested by p.F508del patients. Here we provide novel elements in the mechanism of hsa-miR-99b and hsa-miR-125a biogenesis, and for the role of CFTR and DeltaF508-CFTR on the expression of this miRNA cluster. These findings augment existing data implicating miRNAs as putative CF modifiers." other hsa-mir-125a Cystic Fibrosis 25800681 "Ingenuity Pathway Analysis indicated that hsa-miR-99b and hsa-miR-125a could be associated with the phenotypes manifested by p.F508del patients. Here we provide novel elements in the mechanism of hsa-miR-99b and hsa-miR-125a biogenesis, and for the role of CFTR and DeltaF508-CFTR on the expression of this miRNA cluster. These findings augment existing data implicating miRNAs as putative CF modifiers." other hsa-mir-99b Cystic Fibrosis 25800681 "Ingenuity Pathway Analysis indicated that hsa-miR-99b and hsa-miR-125a could be associated with the phenotypes manifested by p.F508del patients. Here we provide novel elements in the mechanism of hsa-miR-99b and hsa-miR-125a biogenesis, and for the role of CFTR and DeltaF508-CFTR on the expression of this miRNA cluster. These findings augment existing data implicating miRNAs as putative CF modifiers." other hsa-mir-548c Breast Neoplasms 25802200 "we showed that miR-548c-3p is implicated in doxorubicin-treated MCF-7 cell viability, suggesting a role for this miRNA in resistance." other hsa-mir-130b Cholestasis 25802328 "These data support miR-130b as a potential negative regulator of drug metabolism by directly and/or indirectly affecting the expression of several ADME genes. This may be of relevance in pathophysiologic conditions such as cholestasis and inflammation, which are associated with increased miR-130b expression." other hsa-let-7a "Squamous Cell Carcinoma, Lung" 25802847 "The novel candidate key drivers in this refined subnetwork, such as the methylation of ARHGDIB and HOXD3, microRNA let-7a and miR-31, and the CNV of AGAP2, were identified and analyzed." other hsa-mir-20a "Carcinoma, Cervical" 25803820 MiR-20a promotes cervical cancer proliferation and metastasis in vitro and in vivo. other hsa-mir-143 Bladder Neoplasms 25804644 "The cancer-related miR-143, miR-145 and miR-224 were investigated for the first time in the clinical setting of BlCa, and miR-143/145 cluster constitutes a novel marker helpful for providing an enhanced prediction of oncologic outcome for BlCa patients." other hsa-mir-145 Bladder Neoplasms 25804644 "The cancer-related miR-143, miR-145 and miR-224 were investigated for the first time in the clinical setting of BlCa, and miR-143/145 cluster constitutes a novel marker helpful for providing an enhanced prediction of oncologic outcome for BlCa patients." other hsa-mir-224 Bladder Neoplasms 25804644 "The cancer-related miR-143, miR-145 and miR-224 were investigated for the first time in the clinical setting of BlCa, and miR-143/145 cluster constitutes a novel marker helpful for providing an enhanced prediction of oncologic outcome for BlCa patients." other hsa-mir-146a Inflammation 25805648 "the model of endotoxin tolerance is suitable for the antagonistic effects on the dysregulation of ABCA1/G1 induced by high dose of P.g LPS.Conversely, low-dose AGEs did not induce the model of P.g LPS-mediated tolerance." other hsa-mir-1290 "Squamous Cell Carcinoma, Esophageal" 25805931 Our findings suggested that miR-1290 may play an oncogenic role in cellular processes of ESCC. other hsa-mir-200c Neoplasms [unspecific] 25808651 "A Comprehensive Review on miR-200c, A Promising Cancer Biomarker with Therapeutic Potential." other hsa-mir-29 Human Immunodeficiency Virus Infection 25808800 "The miRNA-29 family could influence the clinical progression of HIV-1 infection, the HIV-1 proviral load and the innate immune response against HIV-1." other hsa-mir-9 "Adenocarcinoma, Cervical" 25809226 our results here present a tumor suppressor potential of miR-9 in cervical adenocarcinoma for the first time and suggest that miR-9 could repress tumorigenesis through inhibiting the activity of IL-6/Jak/STAT3 pathway.has-miR-146b-5p other hsa-mir-210 Neoplasms [unspecific] 25809609 The role of hypoxia-induced miR-210 in cancer progression. other hsa-mir-494 "Carcinoma, Nasopharyngeal" 25809707 Functional elucidation of miR-494 in the tumorigenesis of nasopharyngeal carcinoma. other hsa-mir-15b Glioma 25811315 Decreased Expression of miR-15b in Human Gliomas is Associated with Poor Prognosis. other hsa-mir-518a Colorectal Carcinoma 25812680 Downregulation of miR-518a-3p activates the NIK-dependent NF-¦ÊB pathway in colorectal cancer. other hsa-mir-16 "Carcinoma, Renal Cell" 25815587 Upregulated microRNA-16 as an oncogene in renal cell carcinoma. other hsa-mir-103-1 Bipolar Disorder 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-103-1 Schizophrenia 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-124 Bipolar Disorder 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-124 Schizophrenia 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-132 Bipolar Disorder 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-132 Schizophrenia 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-138 Bipolar Disorder 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-138 Schizophrenia 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-206 Bipolar Disorder 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-206 Schizophrenia 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-218-1 Bipolar Disorder 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-218-1 Schizophrenia 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-34a Bipolar Disorder 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-34a Schizophrenia 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-449a Bipolar Disorder 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-449a Schizophrenia 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-9-3 Bipolar Disorder 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-9-3 Schizophrenia 25817407 Our approach of integrating PGC findings with eQTL results can be used to generate specific hypotheses regarding the role of miRNAs in SZ and BD. other hsa-mir-340 Glioblastoma 25817794 "miR-340 inhibits glioblastoma cell proliferation by suppressing CDK6, cyclin-D1 and cyclin-D2." other hsa-mir-124 Colorectal Carcinoma 25818238 MicroRNA-124 inhibits cancer cell growth through PTB1/PKM1/PKM2 feedback cascade in colorectal cancer. other hsa-mir-155 "Lymphoma, Large-Cell, Anaplastic" 25820993 Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation. other hsa-mir-122 "Carcinoma, Hepatocellular" 25823567 Regulation of the oncogenic function of distal-less 4 by microRNA-122 in hepatocellular carcinoma. other hsa-mir-93 Glioma 25823655 miR-93 promotes cell proliferation in gliomas through activation of PI3K/Akt signaling pathway. other hsa-mir-1323 Lung Neoplasms 25823795 Knockdown of microRNA-1323 restores sensitivity to radiation by suppression of PRKDC activity in radiation-resistant lung cancer cells. other hsa-mir-328 Breast Neoplasms 25824027 Arsenic trioxide inhibits breast cancer cell growth via microRNA-328/hERG pathway in MCF-7 cells. other hsa-mir-223 Pleural Mesothelioma 25824152 Loss of miR-223 and JNK Signaling Contribute to Elevated Stathmin in Malignant Pleural Mesothelioma. other hsa-mir-210 Pulmonary Hypertension 25825391 Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension. other hsa-mir-193a Neoplasms [unspecific] 25826780 "Our findings have provided new insights into mechanisms of CIK cells production and tumor cytotoxic function, and shed light on their safety for clinical trial." other hsa-mir-181c Breast Neoplasms 25828099 Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood-brain barrier. other hsa-mir-208a Myocardial Infarction 25828373 Targeting MicroRNA-208a to Suppress Adverse Postmyocardial Infarction Remodelling Related to RNA Activation of Endoglin Gene Expression. other hsa-mir-23a Heart Failure 25829494 Heat shock inhibition of CDK5 increases NOXA levels through miR-23a repression. other hsa-mir-21 Lung Neoplasms 25831148 Abnormal Expression of miR-21 and miR-95 in Cancer Stem-Like Cells is Associated with Radioresistance of Lung Cancer. other hsa-mir-95 Lung Neoplasms 25831148 Abnormal Expression of miR-21 and miR-95 in Cancer Stem-Like Cells is Associated with Radioresistance of Lung Cancer. other hsa-mir-340 Glioblastoma 25831237 miR-340 suppresses glioblastoma multiforme. other hsa-mir-200 "Carcinoma, Colon" 25832648 Loss of miR-200 family in 5-fluorouracil resistant colon cancer drives lymphendothelial invasiveness in vitro. other hsa-mir-451 Glioblastoma 25833239 low levels of glucose affect metabolism and activate cell migration through the miR-451-AMPK control system other hsa-mir-150 "Leukemia, Lymphocytic, Chronic, B-Cell" 25833959 "this study successfully characterized CLL exosomes, demonstrated the control of BCR signaling in the release of CLL exosomes, and uncovered a disease-relevant exosome microRNA profile." other hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 25833959 "this study successfully characterized CLL exosomes, demonstrated the control of BCR signaling in the release of CLL exosomes, and uncovered a disease-relevant exosome microRNA profile." other hsa-mir-223 "Leukemia, Lymphocytic, Chronic, B-Cell" 25833959 "this study successfully characterized CLL exosomes, demonstrated the control of BCR signaling in the release of CLL exosomes, and uncovered a disease-relevant exosome microRNA profile." other hsa-mir-29 "Leukemia, Lymphocytic, Chronic, B-Cell" 25833959 "this study successfully characterized CLL exosomes, demonstrated the control of BCR signaling in the release of CLL exosomes, and uncovered a disease-relevant exosome microRNA profile." other hsa-mir-122 Hepatitis C Virus Infection 25836383 The binding of p68 onto HCV RNA can be specifically inhibited by miR-122 via a competitive binding process. other hsa-mir-182 Glioblastoma 25838542 "miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma." other hsa-mir-199a "Carcinoma, Ovarian" 25839163 The hypoxia-related microRNA miR-199a-3p displays tumor suppressor functions in ovarian carcinoma. other hsa-mir-208 Heart Failure 25840809 miR-208 family is closely associated with the development of cardiac diseases other hsa-mir-208 Vascular Hypertrophy 25840809 miR-208 family is closely associated with the development of cardiac diseases other hsa-mir-203 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 25840888 Effect of microRNA-203 on tumor growth in human hypopharyngeal squamous cell carcinoma. other hsa-mir-132 Pancreatic Neoplasms 25840985 Xenograft tumors treated with ormeloxifene in combination with gemcitabine restored the tumor-suppressor miR-132 and inhibited stromal cell infiltration into the tumor tissues. other hsa-mir-889 "Squamous Cell Carcinoma, Esophageal" 25841337 miR-889 promotes proliferation of esophageal squamous cell carcinomas through DAB2IP. other hsa-mir-942 "Squamous Cell Carcinoma, Esophageal" 25844602 miR-942 promotes cancer stem cell-like traits in esophageal squamous cell carcinoma through activation of Wnt/¦Â-catenin signalling pathway. other hsa-mir-99a Chronic Hepatitis C 25844942 "IFI35, mir-99a and HCV genotype to predict sustained virological response to pegylated-interferon plus ribavirin in chronic hepatitis C." other hsa-mir-154 Lung Neoplasms 25846246 miR-154 suppresses non-small cell lung cancer growth in vitro and in vivo. other hsa-mir-210 Prostate Neoplasms 25846647 "Treatment with MIB led to an induction of miR-210 expression, a hypoxia-related miRNA" other hsa-mir-221 Prostate Neoplasms 25846647 This observation indicates that this miRNA may have a more complex role in prostate cancer development than considered previously.Thus examining the effect of androgen receptor (AR) agonists and antagonists on miRNA expression can provide novel insights into the response of cells to androgen receptor (AR) ligands and subsequent downstream events. other hsa-mir-335 "Carcinoma, Renal Cell, Clear-Cell" 25846734 miR-335 inhibits the proliferation and invasion of clear cell renal cell carcinoma cells through direct suppression of BCL-W. other hsa-mir-9 "Carcinoma, Ovarian" 25846738 MicroRNA-9 promotes tumorigenesis and mediates sensitivity to cisplatin in primary epithelial ovarian cancer cells. other hsa-mir-27b Congenital Heart Diseases 25847058 "The current study revealed for the first time that microRNAs may be important regulators in pulmonary arterial hypertension secondary to congenital heart disease, and demonstrated the correlation between microRNA-27b and pulmonary arterial hypertension with the implication of NOTCH1." other hsa-mir-144 Osteosarcoma 25854173 "MicroRNA-144 inhibits the proliferation, apoptosis, invasion, and migration of osteosarcoma cell line F5M2." other hsa-mir-125a Vascular Disease [unspecific] 25854878 These translational data emphasize the pathogenetic role of miR-125a in pulmonary vascular remodeling. other hsa-mir-122 Hepatitis C Virus Infection 25855736 Regulation of Hepatitis C Virus Genome Replication by Xrn1 and MicroRNA-122 Binding to Individual Sites in the 5' Untranslated Region. other hsa-mir-183 Neoplasms [unspecific] 25856466 "Let-7, mir-98 and mir-183 as biomarkers for cancer and schizophrenia [corrected]." other hsa-mir-98 Neoplasms [unspecific] 25856466 "Let-7, mir-98 and mir-183 as biomarkers for cancer and schizophrenia [corrected]." other hsa-mir-100 Cardiovascular Diseases [unspecific] 25857370 "In endothelial cells, activation of PPAR-¦Ä decreased VLDL receptor expression and VLDL uptake via the induction of miR-100. These results provided a novel mechanism for the vascular protective effect of PPAR-¦Ä agonists." other hsa-mir-29a "Scleroderma, Systemic" 25857445 MicroRNA-29a induces apoptosis via increasing the Bax:Bcl-2 ratio in dermal fibroblasts of patients with systemic sclerosis. other hsa-mir-25 "Carcinoma, Prostate" 25858144 miR-25 Modulates Invasiveness and Dissemination of Human Prostate Cancer Cells via Regulation of ¦Áv- and ¦Á6-Integrin Expression. other hsa-mir-93 Viral Infectious Disease 25858415 Generation of a safe and effective live viral vaccine by virus self-attenuation using species-specific artificial microRNA. other hsa-mir-29c "Leukemia, Lymphocytic, Chronic, B-Cell" 25860243 "Our data identify biological characteristics associated with subset #4 patients, providing further evidence for the putative role of BCR in shaping the features of the tumor cells in CLL." other hsa-mir-497 "Leukemia, Lymphocytic, Chronic, B-Cell" 25860243 "Our data identify biological characteristics associated with subset #4 patients, providing further evidence for the putative role of BCR in shaping the features of the tumor cells in CLL." other hsa-mir-1234 Gastric Neoplasms 25861021 These data provide a theoretical basis for the potential interaction between miRNA and the ¦Â-catenin signaling pathway in GC. other hsa-mir-135b Gastric Neoplasms 25861021 These data provide a theoretical basis for the potential interaction between miRNA and the ¦Â-catenin signaling pathway in GC. other hsa-mir-20a Gastric Neoplasms 25861021 These data provide a theoretical basis for the potential interaction between miRNA and the ¦Â-catenin signaling pathway in GC. other hsa-mir-210 Gastric Neoplasms 25861021 These data provide a theoretical basis for the potential interaction between miRNA and the ¦Â-catenin signaling pathway in GC. other hsa-mir-23b Gastric Neoplasms 25861021 These data provide a theoretical basis for the potential interaction between miRNA and the ¦Â-catenin signaling pathway in GC. other hsa-mir-423 Gastric Neoplasms 25861021 These data provide a theoretical basis for the potential interaction between miRNA and the ¦Â-catenin signaling pathway in GC. other hsa-mir-455 Gastric Neoplasms 25861021 These data provide a theoretical basis for the potential interaction between miRNA and the ¦Â-catenin signaling pathway in GC. other hsa-mir-4739 Gastric Neoplasms 25861021 These data provide a theoretical basis for the potential interaction between miRNA and the ¦Â-catenin signaling pathway in GC. other hsa-mir-494 "Carcinoma, Lung, Non-Small-Cell" 25861022 Expression and clinical evidence of miR-494 and PTEN in non-small cell lung cancer. other hsa-mir-106b Pituitary Neoplasms 25862551 "Our results suggest microRNA involvement in malignant pituitary progression, whereby increased miR-20a, miR-106b and miR-17-5p promote metastasis by attenuating PTEN and TIMP2 in pituitary carcinoma." other hsa-mir-17 Pituitary Neoplasms 25862551 "Our results suggest microRNA involvement in malignant pituitary progression, whereby increased miR-20a, miR-106b and miR-17-5p promote metastasis by attenuating PTEN and TIMP2 in pituitary carcinoma." other hsa-mir-20a Pituitary Neoplasms 25862551 "Our results suggest microRNA involvement in malignant pituitary progression, whereby increased miR-20a, miR-106b and miR-17-5p promote metastasis by attenuating PTEN and TIMP2 in pituitary carcinoma." other hsa-mir-29c Pancreatic Neoplasms 25863127 miR-29c suppresses pancreatic cancer liver metastasis in an orthotopic implantation model in nude mice and affects survival in pancreatic cancer patients. other hsa-mir-222 Cardiovascular Diseases [unspecific] 25863248 These studies implicate miR-222 as necessary for exercise-induced cardiomyocyte growth and proliferation in the adult mammalian heart and show that it is sufficient to protect the heart against adverse remodeling. other hsa-mir-148a Bladder Neoplasms 25865490 miR-148a dependent apoptosis of bladder cancer cells is mediated in part by the epigenetic modifier DNMT1. other hsa-mir-150 "Lymphoma, Large B-Cell, Diffuse" 25866097 miR signature from DLBCL biopsies can discriminate between patients with favorable and poor prognoses. other hsa-mir-155 "Lymphoma, Large B-Cell, Diffuse" 25866097 miR signature from DLBCL biopsies can discriminate between patients with favorable and poor prognoses. other hsa-mir-18a "Lymphoma, Large B-Cell, Diffuse" 25866097 miR signature from DLBCL biopsies can discriminate between patients with favorable and poor prognoses. other hsa-mir-221 "Lymphoma, Large B-Cell, Diffuse" 25866097 miR signature from DLBCL biopsies can discriminate between patients with favorable and poor prognoses. other hsa-mir-222 "Lymphoma, Large B-Cell, Diffuse" 25866097 miR signature from DLBCL biopsies can discriminate between patients with favorable and poor prognoses. other hsa-mir-342 "Lymphoma, Large B-Cell, Diffuse" 25866097 miR signature from DLBCL biopsies can discriminate between patients with favorable and poor prognoses. other hsa-mir-621 Breast Neoplasms 25867061 MiRNA-621 sensitizes breast cancer to chemotherapy by suppressing FBXO11 and enhancing p53 activity. other hsa-mir-149 "Stroke, Ischemic" 25867405 Effect of a pre-microRNA-149 (miR-149) genetic variation on the risk of ischemic stroke in a Chinese Han population. other hsa-mir-103 Myocardial Infarction 25867756 This study provides more details on gene expression regulation and regulators involved in MI progression and recurrence. It also linked up and interpreted many previous results. other hsa-mir-16 Myocardial Infarction 25867756 This study provides more details on gene expression regulation and regulators involved in MI progression and recurrence. It also linked up and interpreted many previous results. other hsa-mir-26 Myocardial Infarction 25867756 This study provides more details on gene expression regulation and regulators involved in MI progression and recurrence. It also linked up and interpreted many previous results. other hsa-mir-320 Myocardial Infarction 25867756 This study provides more details on gene expression regulation and regulators involved in MI progression and recurrence. It also linked up and interpreted many previous results. other hsa-let-7b Melanoma 25868368 The concomitant inhibition of MMP-9 and MMP-13 affects prognosis and survival in skin melanoma. other hsa-mir-21 Melanoma 25868368 The concomitant inhibition of MMP-9 and MMP-13 affects prognosis and survival in skin melanoma. other hsa-mir-451 Osteosarcoma 25869073 Suppression of liver receptor homolog-1 by microRNA-451 represses the proliferation of osteosarcoma cells. other hsa-let-7i Glioblastoma 25869098 MicroRNA profiling of Chinese primary glioblastoma reveals a temozolomide-chemoresistant subtype. other hsa-mir-1238 Glioblastoma 25869098 MicroRNA profiling of Chinese primary glioblastoma reveals a temozolomide-chemoresistant subtype. other hsa-mir-1280 Glioblastoma 25869098 MicroRNA profiling of Chinese primary glioblastoma reveals a temozolomide-chemoresistant subtype. other hsa-mir-151 Glioblastoma 25869098 MicroRNA profiling of Chinese primary glioblastoma reveals a temozolomide-chemoresistant subtype. other hsa-mir-423 Glioblastoma 25869098 MicroRNA profiling of Chinese primary glioblastoma reveals a temozolomide-chemoresistant subtype. other hsa-mir-93 Glioblastoma 25869098 MicroRNA profiling of Chinese primary glioblastoma reveals a temozolomide-chemoresistant subtype. other hsa-mir-938 Glioblastoma 25869098 MicroRNA profiling of Chinese primary glioblastoma reveals a temozolomide-chemoresistant subtype. other hsa-mir-17 Lymphoma 25870038 "Functional interactions among members of the miR-17-92 cluster in lymphocyte development, differentiation and malignant transformation." other hsa-mir-18 Lymphoma 25870038 "Functional interactions among members of the miR-17-92 cluster in lymphocyte development, differentiation and malignant transformation." other hsa-mir-19a Lymphoma 25870038 "Functional interactions among members of the miR-17-92 cluster in lymphocyte development, differentiation and malignant transformation." other hsa-mir-19b-1 Lymphoma 25870038 "Functional interactions among members of the miR-17-92 cluster in lymphocyte development, differentiation and malignant transformation." other hsa-mir-20a Lymphoma 25870038 "Functional interactions among members of the miR-17-92 cluster in lymphocyte development, differentiation and malignant transformation." other hsa-mir-92-1 Lymphoma 25870038 "Functional interactions among members of the miR-17-92 cluster in lymphocyte development, differentiation and malignant transformation." other hsa-mir-101 Graves Disease 25871842 Our study highlights the possibility that miRNA-target gene network may be involved in the pathogenesis of GD and could provide new insights into understanding the pathophysiological mechanisms of GD. other hsa-mir-96 Pulmonary Hypertension 25871906 "Increased 5-HT1BR expression may be a consequence of decreased miRNA-96 expression in female patient human pulmonary artery smooth muscle cell(PASMCs), and this may contribute to the development of pulmonary arterial hypertension (PAH)." other hsa-mir-203 Pancreatic Neoplasms 25872941 This led to the identification of both its target gene miR-203 as a major drug sensitizer other hsa-mir-155 Human Immunodeficiency Virus Infection 25873391 "we demonstrate that TRIM32, an E3 ubiquitin ligase, promotes reactivation from latency by directly modifying I¦ÊB¦Á, leading to a novel mechanism of NF-¦ÊB induction not involving I¦ÊB kinase activation." other hsa-mir-326 Thrombosis 25875481 "The effect of miR-326 appeared to be limited to apoptosis,with no significant effect on platelet activation. These results provide new insight into the molecular mechanisms affecting differential platelet gene regulation, which may increase understanding of the role of platelet apoptosis in multiple diseases." other hsa-mir-494 "Carcinoma, Cervical" 25877755 MiRNA-494 inhibits metastasis of cervical cancer through Pttg1. other hsa-mir-23a "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 25879432 "miR-23a, an independent prognostic factor for laryngeal cancer,participates in the onset and progression of laryngeal cancer." other hsa-mir-21 Breast Neoplasms 25880495 Formulation of Anti-miR-21 and 4-Hydroxytamoxifen Co-loaded Biodegradable Polymer Nanoparticles and Their Antiproliferative Effect on Breast Cancer Cells. other hsa-mir-7 Schizophrenia 25882257 MicroRNA-7/Shank3 axis involved in schizophrenia pathogenesis. other hsa-mir-21 Atherosclerosis 25882990 "In atherosclerosis, miR-21 is increased in the aorta and associated with vitamin D deficiency. Vitamin D deficiency may influence aberrant miR-21 expression in vasculature and bone contributing to the concurrent development of atherosclerosis and osteoporosis." other hsa-mir-141 Bladder Neoplasms 25884322 "MiRNA-141 and miRNA-200b play important roles in the invasive ability and EMT phenotype of bladder cancer. Detection of miRNA-141 and miRNA-200b can help to identify patients undergoing cystectomy who are likely to have lymph node metastasis, and therefore those who may benefit from super-extended PLND." other hsa-mir-200b Bladder Neoplasms 25884322 "MiRNA-141 and miRNA-200b play important roles in the invasive ability and EMT phenotype of bladder cancer. Detection of miRNA-141 and miRNA-200b can help to identify patients undergoing cystectomy who are likely to have lymph node metastasis, and therefore those who may benefit from super-extended PLND." other hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 25886051 Role of microRNA in chronic lymphocytic leukemia onset and progression. other hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 25886051 Role of microRNA in chronic lymphocytic leukemia onset and progression. other hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 25886051 Role of microRNA in chronic lymphocytic leukemia onset and progression. other hsa-mir-17 "Leukemia, Lymphocytic, Chronic, B-Cell" 25886051 Role of microRNA in chronic lymphocytic leukemia onset and progression. other hsa-mir-181b "Leukemia, Lymphocytic, Chronic, B-Cell" 25886051 Role of microRNA in chronic lymphocytic leukemia onset and progression. other hsa-mir-29 "Leukemia, Lymphocytic, Chronic, B-Cell" 25886051 Role of microRNA in chronic lymphocytic leukemia onset and progression. other hsa-mir-34 "Leukemia, Lymphocytic, Chronic, B-Cell" 25886051 Role of microRNA in chronic lymphocytic leukemia onset and progression. other hsa-mir-92 "Leukemia, Lymphocytic, Chronic, B-Cell" 25886051 Role of microRNA in chronic lymphocytic leukemia onset and progression. other hsa-mir-142 Crohn Disease 25886994 "A panel of miRNAs(miR-19a, miR-21, miR-31, miR-101, miR-146a, and miR-375) may be used as markers to identify and discriminate between CD and UC." other hsa-mir-21 Crohn Disease 25886994 "A panel of miRNAs(miR-19a, miR-21, miR-31, miR-101, miR-146a, and miR-375) may be used as markers to identify and discriminate between CD and UC." other hsa-mir-31 Crohn Disease 25886994 "A panel of miRNAs(miR-19a, miR-21, miR-31, miR-101, miR-146a, and miR-375) may be used as markers to identify and discriminate between CD and UC." other hsa-mir-1307 Ovarian Neoplasms 25887170 Our results suggest that miRNA-1307 may play a role in the development of chemoresistance in ovarian cancer. other hsa-mir-34a Cardiovascular Diseases [unspecific] 25887273 "Also, miR-125a-5p/-351, miR-200c/-429, miR-106b/-17, miR-363/-92b, miR-181b/-181d, miR-19a/-19b, let-7d/-7f, miR-18a/-18b, miR-128/-27b and miR-106a/-291a-3p pairs exhibited significant synergy and their association to aging and/or cardiovascular diseases is supported in many cases by a disease database and previous studies." other hsa-mir-17 Neoplasms [unspecific] 25887381 "Our findings therefore identify the miR-17-92 cluster as a functionally determining family of miRNAs in CSCs, and highlight the putative potential of developing modulators of this cluster to overcome drug resistance in pancreatic CSCs." other hsa-mir-18 Neoplasms [unspecific] 25887381 "Our findings therefore identify the miR-17-92 cluster as a functionally determining family of miRNAs in CSCs, and highlight the putative potential of developing modulators of this cluster to overcome drug resistance in pancreatic CSCs." other hsa-mir-19a Neoplasms [unspecific] 25887381 "Our findings therefore identify the miR-17-92 cluster as a functionally determining family of miRNAs in CSCs, and highlight the putative potential of developing modulators of this cluster to overcome drug resistance in pancreatic CSCs." other hsa-mir-19b-1 Neoplasms [unspecific] 25887381 "Our findings therefore identify the miR-17-92 cluster as a functionally determining family of miRNAs in CSCs, and highlight the putative potential of developing modulators of this cluster to overcome drug resistance in pancreatic CSCs." other hsa-mir-20a Neoplasms [unspecific] 25887381 "Our findings therefore identify the miR-17-92 cluster as a functionally determining family of miRNAs in CSCs, and highlight the putative potential of developing modulators of this cluster to overcome drug resistance in pancreatic CSCs." other hsa-mir-92-1 Neoplasms [unspecific] 25887381 "Our findings therefore identify the miR-17-92 cluster as a functionally determining family of miRNAs in CSCs, and highlight the putative potential of developing modulators of this cluster to overcome drug resistance in pancreatic CSCs." other hsa-mir-125b "Carcinoma, Hepatocellular" 25889022 This finding provides the novel evidence for GLPS on inhibition of HCC through miR-125b inhibiting Tregs accumulation and function. other hsa-mir-141 Neoplasms [unspecific] 25889350 "The DNA tweezers also show high selectivity toward the fuel strand and can be used to monitor miR-141 expression in cancer cells, which provides new opportunities for the application of the dynamic DNA devices in clinical diagnostics." other hsa-mir-146a Japanese Encephalitis Virus Infection 25889446 Upregulation of miR-146a by JEV JaOArS982 strain leads to suppression of NF-¦ÊB activity and disruption of antiviral Jak-STAT signaling which helps the virus to evade the cellular immune response. This effect of JEV infection on miR-146a expression was found to be strain specific. other hsa-mir-21 Muscular Dystrophy 25892183 Opposing roles of miR-21 and miR-29 in the progression of fibrosis in Duchenne muscular dystrophy. other hsa-mir-29 Muscular Dystrophy 25892183 Opposing roles of miR-21 and miR-29 in the progression of fibrosis in Duchenne muscular dystrophy. other hsa-mir-31 "Carcinoma, Cervical" 25894339 Our results suggested that miR-31 plays an oncogenetic role in the development and progression of cervical cancer. other hsa-mir-129 Ovarian Neoplasms 25895125 A novel role for microRNA-129-5p in inhibiting ovarian cancer cell proliferation and survival via direct suppression of transcriptional co-activators YAP and TAZ. other hsa-mir-34a Neoplasms [unspecific] 25896587 "miR-34a plays an important role in the anti-tumor effects of querctin in HCC, miR-34a may be a tiemolecule between the p53 and SIRT1 and is composed of a p53/miR-34a/SIRT1 signal feedback loop, which could enhance apoptosis signal and significantly promote cell apoptosis." other hsa-mir-16 Gastric Neoplasms 25897338 Circulating MiR-16-5p and MiR-19b-3p as Two Novel Potential Biomarkers to Indicate Progression of Gastric Cancer. other hsa-mir-19b Gastric Neoplasms 25897338 Circulating MiR-16-5p and MiR-19b-3p as Two Novel Potential Biomarkers to Indicate Progression of Gastric Cancer. other hsa-mir-221 Gastrointestinal Stromal Tumor 25898773 miRNA-221 and miRNA-222 induce apoptosis via the KIT/AKT signalling pathway in gastrointestinal stromal tumours. other hsa-mir-222 Gastrointestinal Stromal Tumor 25898773 miRNA-221 and miRNA-222 induce apoptosis via the KIT/AKT signalling pathway in gastrointestinal stromal tumours. other hsa-mir-1 Neoplasms [unspecific] 25899823 "Our results suggest that the degradation status of ribosomal RNA is not always applicable to mRNA and microRNA. In fact, the stabilities of these RNA classes to exposure to ribonucleases are independent from each other, with microRNA being more stable than mRNA. The relative stability of microRNAs supports their potential and further development as biomarkers in a range of applications." other hsa-mir-208 Neoplasms [unspecific] 25899823 "Our results suggest that the degradation status of ribosomal RNA is not always applicable to mRNA and microRNA. In fact, the stabilities of these RNA classes to exposure to ribonucleases are independent from each other, with microRNA being more stable than mRNA. The relative stability of microRNAs supports their potential and further development as biomarkers in a range of applications." other hsa-mir-501 Neoplasms [unspecific] 25899823 "Our results suggest that the degradation status of ribosomal RNA is not always applicable to mRNA and microRNA. In fact, the stabilities of these RNA classes to exposure to ribonucleases are independent from each other, with microRNA being more stable than mRNA. The relative stability of microRNAs supports their potential and further development as biomarkers in a range of applications." other hsa-mir-21 Lung Neoplasms 25901472 "The present study reports that DEPs increased miR-21 expression and then activated the PTEN/PI3K/AKT pathway in human bronchial epithelial (HBE) cells, which may serve as an important carcinogenic mechanism. However, the data revealed that short-term exposure to a high DEP concentration did not cause evident cell carcinogenesis in HBE cells." other hsa-mir-21 Endomyocardial Fibrosis 25903305 Downregulation of miR-21 and p-ERK/ERK were observed in myocardial fibroblasts treated with UA in a dose-dependent manner compared with the control group both in vitro and in vivo. other hsa-mir-21 Heart Failure 25903305 Downregulation of miR-21 and p-ERK/ERK were observed in myocardial fibroblasts treated with UA in a dose-dependent manner compared with the control group both in vitro and in vivo. other hsa-mir-21 Vascular Hypertrophy 25903305 Downregulation of miR-21 and p-ERK/ERK were observed in myocardial fibroblasts treated with UA in a dose-dependent manner compared with the control group both in vitro and in vivo. other hsa-let-7e Acute Coronary Syndrome 25903651 "These results demonstrate a significant reprogramming of the platelet miRNome during activation, with consequent significant changes in platelet proteome and provide for the first time substantial evidence that fine-tuning of resident mRNA translation by miRNAs is a key event in platelet pathophysiology." other hsa-mir-107 Acute Coronary Syndrome 25903651 "These results demonstrate a significant reprogramming of the platelet miRNome during activation, with consequent significant changes in platelet proteome and provide for the first time substantial evidence that fine-tuning of resident mRNA translation by miRNAs is a key event in platelet pathophysiology." other hsa-mir-15b Acute Coronary Syndrome 25903651 "These results demonstrate a significant reprogramming of the platelet miRNome during activation, with consequent significant changes in platelet proteome and provide for the first time substantial evidence that fine-tuning of resident mRNA translation by miRNAs is a key event in platelet pathophysiology." other hsa-mir-486 Acute Coronary Syndrome 25903651 "These results demonstrate a significant reprogramming of the platelet miRNome during activation, with consequent significant changes in platelet proteome and provide for the first time substantial evidence that fine-tuning of resident mRNA translation by miRNAs is a key event in platelet pathophysiology." other hsa-mir-92b Acute Coronary Syndrome 25903651 "These results demonstrate a significant reprogramming of the platelet miRNome during activation, with consequent significant changes in platelet proteome and provide for the first time substantial evidence that fine-tuning of resident mRNA translation by miRNAs is a key event in platelet pathophysiology." other hsa-mir-103 Glioblastoma 25903655 "CSF exosomes were enriched for miRNAs relative to CSF microvesicles. In CSF, there is an average of one molecule of miRNA per 150-25,000 EVs. Most EVs derived from clinical biofluids are devoid of miRNA content." other hsa-mir-125 Glioblastoma 25903655 "CSF exosomes were enriched for miRNAs relative to CSF microvesicles. In CSF, there is an average of one molecule of miRNA per 150-25,000 EVs. Most EVs derived from clinical biofluids are devoid of miRNA content." other hsa-mir-21 Glioblastoma 25903655 "CSF exosomes were enriched for miRNAs relative to CSF microvesicles. In CSF, there is an average of one molecule of miRNA per 150-25,000 EVs. Most EVs derived from clinical biofluids are devoid of miRNA content." other hsa-mir-24 Glioblastoma 25903655 "CSF exosomes were enriched for miRNAs relative to CSF microvesicles. In CSF, there is an average of one molecule of miRNA per 150-25,000 EVs. Most EVs derived from clinical biofluids are devoid of miRNA content." other hsa-mir-145 "Adenocarcinoma, Gastric" 25904219 "Downregulation of the Genes Involved in Reprogramming (SOX2, c-MYC, miR-302,miR-145, and P21) in Gastric Adenocarcinoma." other hsa-mir-302 "Adenocarcinoma, Gastric" 25904219 "Downregulation of the Genes Involved in Reprogramming (SOX2, c-MYC, miR-302,miR-145, and P21) in Gastric Adenocarcinoma." other hsa-mir-146a "Lymphoma, B-Cell" 25906746 Together our findings illuminate a bona fide role for miR-146a in the modulation of B-cell oncogenesis and reveal the importance of understanding microRNA function in a cell- and disease-specific context. other hsa-mir-150 Breast Neoplasms 25907662 "These results all indicated that when analyzing miRNAs in surgical pathology specimens of breast cancer as a biomarker, they should be examined as a cluster through miRNA profiling, rather than relying on the analysis of a single miRNA." other hsa-mir-15b Breast Neoplasms 25907662 "These results all indicated that when analyzing miRNAs in surgical pathology specimens of breast cancer as a biomarker, they should be examined as a cluster through miRNA profiling, rather than relying on the analysis of a single miRNA." other hsa-mir-191 Breast Neoplasms 25907662 "These results all indicated that when analyzing miRNAs in surgical pathology specimens of breast cancer as a biomarker, they should be examined as a cluster through miRNA profiling, rather than relying on the analysis of a single miRNA." other hsa-mir-200c Breast Neoplasms 25907662 "These results all indicated that when analyzing miRNAs in surgical pathology specimens of breast cancer as a biomarker, they should be examined as a cluster through miRNA profiling, rather than relying on the analysis of a single miRNA." other hsa-mir-21 Breast Neoplasms 25907662 "These results all indicated that when analyzing miRNAs in surgical pathology specimens of breast cancer as a biomarker, they should be examined as a cluster through miRNA profiling, rather than relying on the analysis of a single miRNA." other hsa-mir-25 Breast Neoplasms 25907662 "These results all indicated that when analyzing miRNAs in surgical pathology specimens of breast cancer as a biomarker, they should be examined as a cluster through miRNA profiling, rather than relying on the analysis of a single miRNA." other hsa-mir-96 Breast Neoplasms 25907662 "These results all indicated that when analyzing miRNAs in surgical pathology specimens of breast cancer as a biomarker, they should be examined as a cluster through miRNA profiling, rather than relying on the analysis of a single miRNA." other hsa-mir-34a Lung Neoplasms 25909221 miR-497 and miR-34a retard lung cancer growth by co-inhibiting cyclin E1 (CCNE1). other hsa-mir-497 Lung Neoplasms 25909221 miR-497 and miR-34a retard lung cancer growth by co-inhibiting cyclin E1 (CCNE1). other hsa-let-7 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-122 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-126 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-141 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-182 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-200 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-205 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-21 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-221 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-222 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-29 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-34 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-522 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-592 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-7 Lung Neoplasms 25910758 MicroRNA as tools and therapeutics in lung cancer. other hsa-mir-16 Lung Neoplasms 25912305 Lung tumorigenesis induced by human vascular endothelial growth factor (hVEGF)-A165 overexpression in transgenic mice and amelioration of tumor formation by miR-16. other hsa-let-7e Systemic Lupus Erythematosus 25912736 "These data suggest that 17¦Â-estradiol amplifies the activation of IFN-¦Á signaling in B cells via IKK¦Å by down-regulating the expression of let-7e-5p, miR-98-5p and miR-145a-5p. Our findings may provide a new perspective for understanding the mechanism underlying the gender difference in the prevalence of SLE." other hsa-mir-145a Systemic Lupus Erythematosus 25912736 "These data suggest that 17¦Â-estradiol amplifies the activation of IFN-¦Á signaling in B cells via IKK¦Å by down-regulating the expression of let-7e-5p, miR-98-5p and miR-145a-5p. Our findings may provide a new perspective for understanding the mechanism underlying the gender difference in the prevalence of SLE." other hsa-mir-98 Systemic Lupus Erythematosus 25912736 "These data suggest that 17¦Â-estradiol amplifies the activation of IFN-¦Á signaling in B cells via IKK¦Å by down-regulating the expression of let-7e-5p, miR-98-5p and miR-145a-5p. Our findings may provide a new perspective for understanding the mechanism underlying the gender difference in the prevalence of SLE." other hsa-mir-125b Leukemia 25915540 The Phosphoinositide 3-Kinase p110¦Á Isoform Regulates Leukemia Inhibitory Factor Receptor Expression via c-Myc and miR-125b to Promote Cell Proliferation in Medulloblastoma. other hsa-mir-149 Neoplasms [unspecific] 25916550 Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment. other hsa-mir-155 Ischemia-Reperfusion Injury 25916938 MicroRNA-155 aggravates ischemia-reperfusion injury by modulation of inflammatory cell recruitment and the respiratory oxidative burst. other hsa-mir-101 Thyroid Adenomas 25916957 "These results support a role for miRNA in the regulation of extracellular matrix proteins and tissue remodeling occurring during tumor development, and in the important negative feedback of the cAMP pathway, which limits the consequences of its constitutive activation in these tumors." other hsa-mir-144 Thyroid Adenomas 25916957 "These results support a role for miRNA in the regulation of extracellular matrix proteins and tissue remodeling occurring during tumor development, and in the important negative feedback of the cAMP pathway, which limits the consequences of its constitutive activation in these tumors." other hsa-mir-155 Neoplasms [unspecific] 25918453 "Our data suggest that single miR-155 profiling has a potential to be used as a screening test for various carcinomas, and parallel testing of miR-155 confers an improved specificity compared to single miR-155 analysis." other hsa-mir-224 Colorectal Carcinoma 25919696 "We describe a novel mechanism of KRAS regulation, and highlight the clinical utility of colorectal cancer-specific miRNAs as disease progression or clinical response biomarkers." other hsa-mir-141 "Carcinoma, Prostate" 25921227 The work demonstrated here thus offers new opportunities for the construction of functional DNA nanostructures and for the application of these DNA nanostructures as an effective signal amplification means in the sensitive detection of nucleic acid biomarkers. other hsa-mir-302a Prostate Neoplasms 25922934 MicroRNA-302a Suppresses Tumor Cell Proliferation by Inhibiting AKT in Prostate Cancer. other hsa-mir-150 Colorectal Carcinoma 25924769 "We identified two circulating miRNAs capable of distinguishing patient groups with different diseases of the colon from each other, and patients with advanced cancer from benign disease groups." other hsa-mir-34a Colorectal Carcinoma 25924769 "We identified two circulating miRNAs capable of distinguishing patient groups with different diseases of the colon from each other, and patients with advanced cancer from benign disease groups." other hsa-let-7 Multiple Myeloma 25925570 "Our study establishes that the ribonuclease DIS3, targeting LIN28B, sustains the maturation of let-7 miRNAs and suggests the increased translation of critical oncogenes as one of the biological outcomes of DIS3 inactivation." other hsa-mir-497 Colorectal Carcinoma 25926384 MiR-497 promotes metastasis of colorectal cancer cells through Nrdp1 inhibition. other hsa-mir-148a Breast Neoplasms 25928008 Estradiol induces HOTAIR levels via GPER-mediated miR-148a inhibition in breast cancer. other hsa-mir-155 Systemic Lupus Erythematosus 25929465 "These findings provide new insight into the mechanism underlying decreased CD1d expression on B cells in SLE, suggesting that inhibition of inflammation may increase CD1d expression in B cells to ameliorate SLE via modulating iNKT cells." other hsa-mir-497 Colorectal Carcinoma 25929865 miRNA-497 Enhances the Sensitivity of Colorectal Cancer Cells to Neoadjuvant Chemotherapeutic Drug. other hsa-mir-429 "Carcinoma, Hepatocellular" 25931210 our results here defined miR-429 as a key inducer for HCC pathogenesis and metastasis with potential utility for tumor intervention. other hsa-mir-199a Osteosarcoma 25931818 Polymeric nanoparticle-based delivery of microRNA-199a-3p inhibits proliferation and growth of osteosarcoma cells. other hsa-mir-106b Ovary Mixed Epithelial Carcinoma 25933027 Inhibition of Ovarian Epithelial Carcinoma Tumorigenesis and Progression by microRNA 106b Mediated through the RhoC Pathway. other hsa-mir-10a Breast Neoplasms 25934412 "The data presented supports a potential tumour suppressor role for miR-10a in breast cancer, and highlights retinoic acid as a positive regulator of the microRNA." other hsa-let-7c Cerebral Ischemia 25934573 MicroRNA let-7c-5p protects against cerebral ischemia injury via mechanisms involving the inhibition of microglia activation. other hsa-mir-19 Colorectal Carcinoma 25934693 miR-19-Mediated Inhibition of Transglutaminase-2 Leads to Enhanced Invasion and Metastasis in Colorectal Cancer. other hsa-mir-99a Prostate Neoplasms 25937401 A combination of low Ku80 expression and highly-induced miR-99a expression could be a promising marker for predicting rectal bleeding after radiotherapy. other hsa-mir-135b "Squamous Cell Carcinoma, Skin or Unspecific" 25938461 MicroRNA-135b Regulates Leucine Zipper Tumor Suppressor 1 in Cutaneous Squamous Cell Carcinoma. other hsa-mir-141 Multiple Sclerosis 25938517 "According to our results, miR-141 and miR-200a may be key miRNAs in progression of symptoms of MS through inducing differentiation of Th17 cells and inhibiting differentiation to Treg cells. Our data suggest that these miRNAs may probably inhibit negative regulators of Th17 cell differentiation, thus promoting its differentiation." other hsa-mir-200a Multiple Sclerosis 25938517 "According to our results, miR-141 and miR-200a may be key miRNAs in progression of symptoms of MS through inducing differentiation of Th17 cells and inhibiting differentiation to Treg cells. Our data suggest that these miRNAs may probably inhibit negative regulators of Th17 cell differentiation, thus promoting its differentiation." other hsa-mir-203 Alopecia 25939713 RBM28 contributes to HF growth regulation through modulation of miR-203 and p63 activity. other hsa-mir-34a Neoplasms [unspecific] 25939820 Multivalent aptamer-RNA based fluorescent probes for carrier-free detection of cellular microRNA-34a in mucin1-expressing cancer cells. other hsa-mir-301a Prostate Neoplasms 25940439 Infiltrated pre-adipocytes increase prostate cancer metastasis via modulation of the miR-301a/androgen receptor (AR)/TGF-¦Â1/Smad/MMP9 signals. other hsa-mir-940 "Carcinoma, Hepatocellular" 25940592 MiR-940 inhibits hepatocellular carcinoma growth and correlates with prognosis of hepatocellular carcinoma patients. other hsa-mir-218 Neoplasms [unspecific] 25940608 "A feedback loop between c-Src and miR-218 was revealed where c-Src inhibits transcription of SLIT2, which intronically hosts miR-218. These results show a novel regulatory pathway for RPTP¦Á-c-Src signalling." other hsa-mir-9 Colorectal Carcinoma 25940709 Regulation of UHRF1 by microRNA-9 modulates colorectal cancer cell proliferation and apoptosis. other hsa-mir-371 Neoplasms [unspecific] 25941115 MiR-371-373 cluster acts as a tumor-suppressor-miR and promotes cell cycle arrest in unrestricted somatic stem cells. other hsa-mir-373 Neoplasms [unspecific] 25941115 MiR-371-373 cluster acts as a tumor-suppressor-miR and promotes cell cycle arrest in unrestricted somatic stem cells. other hsa-mir-409 Kaposi Sarcoma 25942495 our data provide a more detailed understanding of KSHV latency and guide further studies of the biological significance of these changes. other hsa-mir-708 Kaposi Sarcoma 25942495 our data provide a more detailed understanding of KSHV latency and guide further studies of the biological significance of these changes. other hsa-mir-21 Neoplasms [unspecific] 25943710 We believe that this proposed sensitive and specific assay has great potential as a quantification method for miRNA detection in biomedical research and clinical diagnosis. other hsa-mir-223 Diabetes Mellitus 25944670 "Thus, calpain inhibition may be one means of normalizing platelet miRNA processing as well as platelet function in diabetes mellitus." other hsa-mir-15a Neoplasms [unspecific] 25945419 these data demonstrate that miR-15a/16 induced autophagy contribute partly to their inhibition of cell proliferation and enhanced chemotherapeutic efficacy of camptothecin(CPT). other hsa-mir-16 Neoplasms [unspecific] 25945419 these data demonstrate that miR-15a/16 induced autophagy contribute partly to their inhibition of cell proliferation and enhanced chemotherapeutic efficacy of camptothecin(CPT). other hsa-let-7b Neoplasms [unspecific] 25946136 Let-7 may represent a new class of chemosensitizer for the treatment of KRAS mutant tumors. other hsa-mir-148a Pancreatic Neoplasms 25950085 The Interplay Between miR-148a and DNMT1 Might be Exploited for Pancreatic Cancer Therapy. other hsa-mir-106a Glioma 25950430 The Effects and Molecular Mechanisms of MiR-106a in Multidrug Resistance Reversal in Human Glioma U87/DDP and U251/G Cell Lines. other hsa-mir-4728 Neoplasms [unspecific] 25950472 ErbB2-intronic microRNA-4728: a novel tumor suppressor and antagonist of oncogenic MAPK signaling. other hsa-mir-638 Lung Neoplasms 25952770 miR-638 is a new biomarker for outcome prediction of non-small cell lung cancer patients receiving chemotherapy. other hsa-mir-137 "Carcinoma, Ovarian" 25955305 MicroRNA-137 suppresses tumor growth in epithelial ovarian cancer in vitro and in vivo. other hsa-mir-206 Thyroid Neoplasms 25955685 miR-206 inhibits metastasis-relevant traits by degrading MRTF-A in anaplastic thyroid cancer. other hsa-mir-221 Pancreatic Neoplasms 25955843 Metformin Causes G1-Phase Arrest via Down-Regulation of MiR-221 and Enhances TRAIL Sensitivity through DR5 Up-Regulation in Pancreatic Cancer Cells. other hsa-mir-650 Prostate Neoplasms 25956032 Oncogenic Activity of miR-650 in Prostate Cancer Is Mediated by Suppression of CSR1 Expression. other hsa-mir-132 Brain Disease [unspecific] 25957996 "our findings demonstrate the novel role of TLR4-related microRNAs, especially miR-132, in the regulation of MRP8-induced astrocyte activation and highlight the importance of miR-132 in the modulation of innate immune response induced by endogenous ligands in neurological diseases." other hsa-mir-146a Brain Disease [unspecific] 25957996 "our findings demonstrate the novel role of TLR4-related microRNAs, especially miR-132, in the regulation of MRP8-induced astrocyte activation and highlight the importance of miR-132 in the modulation of innate immune response induced by endogenous ligands in neurological diseases." other hsa-mir-155 Brain Disease [unspecific] 25957996 "our findings demonstrate the novel role of TLR4-related microRNAs, especially miR-132, in the regulation of MRP8-induced astrocyte activation and highlight the importance of miR-132 in the modulation of innate immune response induced by endogenous ligands in neurological diseases." other hsa-mir-126 Cardiovascular Diseases [unspecific] 25958013 "This review describes our current understanding of extracellular vesicle miRNA transfer, demonstrating the roles of miR-126, miR-146a, miR-143, and other miRNAs being shuttled from endothelial cells, stem cells, fibroblasts and others into myocytes, endothelial cells, and smooth muscle cells to activate cellular changes and modulate disease phenotypes." other hsa-mir-143 Cardiovascular Diseases [unspecific] 25958013 "This review describes our current understanding of extracellular vesicle miRNA transfer, demonstrating the roles of miR-126, miR-146a, miR-143, and other miRNAs being shuttled from endothelial cells, stem cells, fibroblasts and others into myocytes, endothelial cells, and smooth muscle cells to activate cellular changes and modulate disease phenotypes." other hsa-mir-146a Cardiovascular Diseases [unspecific] 25958013 "This review describes our current understanding of extracellular vesicle miRNA transfer, demonstrating the roles of miR-126, miR-146a, miR-143, and other miRNAs being shuttled from endothelial cells, stem cells, fibroblasts and others into myocytes, endothelial cells, and smooth muscle cells to activate cellular changes and modulate disease phenotypes." other hsa-mir-194 "Squamous Cell Carcinoma, Oral" 25960215 miR-194 regulated AGK and inhibited cell proliferation of oral squamous cell carcinoma by reducing PI3K-Akt-FoxO3a signaling. other hsa-mir-143 Breast Neoplasms 25961039 "In our integrated genomics analysis and experimental validation, a new frame to predict candidate biomarkers of breast cancer subtype is provided and offers assistance in order to understand the potential disease etiology of the breast cancer subtypes." other hsa-mir-145 Breast Neoplasms 25961039 "In our integrated genomics analysis and experimental validation, a new frame to predict candidate biomarkers of breast cancer subtype is provided and offers assistance in order to understand the potential disease etiology of the breast cancer subtypes." other hsa-mir-744 "Carcinoma, Nasopharyngeal" 25961434 MiR-744 functions as a proto-oncogene in nasopharyngeal carcinoma progression and metastasis via transcriptional control of ARHGAP5. other hsa-mir-21 Atherosclerosis 25961718 resveratrol significantly reduced miR-21 expression other hsa-mir-144 Uveal Melanoma 25961751 MiR-144 Inhibits Uveal Melanoma Cell Proliferation and Invasion by Regulating c-Met Expression. other hsa-mir-30a "Carcinoma, Ovarian, Serous" 25962395 Urinary microRNA-30a-5p is a potential biomarker for ovarian serous adenocarcinoma. other hsa-mir-214 "Squamous Cell Carcinoma, Tongue" 25962755 Cantharidin inhibits cell proliferation and promotes apoptosis in tongue squamous cell carcinoma through suppression of miR-214 and regulation of p53 and Bcl-2/Bax. other hsa-mir-18a "Carcinoma, Cervical" 25963391 MicroRNA-18a enhances the radiosensitivity of cervical cancer cells by promoting radiation-induced apoptosis. other hsa-mir-183 Liver Diseases [unspecific] 25963660 These results indicate that the modulation of miRNA processing by COX-2 is a key event in insulin signaling in liver and has potential clinical implications for the management of various hepatic dysfunctions. other hsa-mir-122 Hepatitis C Virus Infection 25963774 The mechanism of HCV dyslipidemia is complex and could partly relate to the effect of miR-122 on lipid metabolism which requires further evaluation in a larger study. other hsa-mir-125a Autoimmune Diseases [unspecific] 25963922 "Using a chemically synthesized miR-125a analogue,we show potential to re-programme the immune homeostasis in EAE models. These findings point to miR-125a as a critical factor that controls autoimmune diseases by stabilizing Treg-mediated immune homeostasis." other hsa-mir-21 "Leukemia, Myeloid, Chronic" 25964959 "we demonstrate that in two CML cell lines exhibiting different biological characteristics, LQB-118 modulates NF¦ÊB subcellular localization, apparently independently of the AKT and MAPK pathways, partially inhibits proteasome activity, and alters the expression of microRNAs -9 and -21." other hsa-mir-9 "Leukemia, Myeloid, Chronic" 25964959 "we demonstrate that in two CML cell lines exhibiting different biological characteristics, LQB-118 modulates NF¦ÊB subcellular localization, apparently independently of the AKT and MAPK pathways, partially inhibits proteasome activity, and alters the expression of microRNAs -9 and -21." other hsa-mir-424 "Squamous Cell Carcinoma, Tongue" 25965165 "Our patient data show that microRNA-424 alterations are a marker of field cancerisation specific for tongue tumourigenesis, which also could have a role in development of tongue squamous cell carcinoma." other hsa-mir-155 Bladder Neoplasms 25965824 MicroRNA-155 promotes bladder cancer growth by repressing the tumor suppressor DMTF1. other hsa-let-7a Pregnancy Complications [unspecific] 25965838 "For samples measured preconception, ROC curve analysis demonstrated AUC 0.81 for adverse pregnancy outcome. Maternal PBMC microRNA can identify high-risk patients likely to benefit from immunotherapy with improved sensitivity and specificity compared with standard immune assays." other hsa-mir-132 Pregnancy Complications [unspecific] 25965838 "For samples measured preconception, ROC curve analysis demonstrated AUC 0.81 for adverse pregnancy outcome. Maternal PBMC microRNA can identify high-risk patients likely to benefit from immunotherapy with improved sensitivity and specificity compared with standard immune assays." other hsa-mir-146a Pregnancy Complications [unspecific] 25965838 "For samples measured preconception, ROC curve analysis demonstrated AUC 0.81 for adverse pregnancy outcome. Maternal PBMC microRNA can identify high-risk patients likely to benefit from immunotherapy with improved sensitivity and specificity compared with standard immune assays." other hsa-mir-155 Pregnancy Complications [unspecific] 25965838 "For samples measured preconception, ROC curve analysis demonstrated AUC 0.81 for adverse pregnancy outcome. Maternal PBMC microRNA can identify high-risk patients likely to benefit from immunotherapy with improved sensitivity and specificity compared with standard immune assays." other hsa-mir-16 Pregnancy Complications [unspecific] 25965838 "For samples measured preconception, ROC curve analysis demonstrated AUC 0.81 for adverse pregnancy outcome. Maternal PBMC microRNA can identify high-risk patients likely to benefit from immunotherapy with improved sensitivity and specificity compared with standard immune assays." other hsa-mir-122 "Carcinoma, Hepatocellular" 25965999 "G¦Á12 overexpressed in hepatocellular carcinoma reduces microRNA-122 expression via HNF4¦Á inactivation, which causes c-Met induction." other hsa-mir-200c "Carcinoma, Breast" 25967125 "our data suggests that expression of miR-200c-141 and ?Np63 in D492M can reverse EMT resulting in luminal- and myoepithelial differentiation, respectively,demonstrating the importance of these molecules in epithelial integrity in the human breast." other hsa-mir-145 Prostate Neoplasms 25969144 miR-145 suppress the androgen receptor in prostate cancer cells and correlates to prostate cancer prognosis. other hsa-mir-21 "Carcinoma, Hepatocellular" 25969534 Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells. other hsa-mir-34a Oral Neoplasms 25973020 MiR-34a inhibits oral cancer progression partially by repression of interleukin-6-receptor. other hsa-mir-101 Pheochromocytoma 25973039 Role of miR-101 in pheochromocytoma patients with SDHD mutation. other hsa-mir-365 "Carcinoma, Hepatocellular" 25973057 Prognostic significance and anti-proliferation effect of microRNA-365 in hepatocellular carcinoma. other hsa-mir-27a "Carcinoma, Renal Cell" 25973137 miR-27a promotes cell proliferation and metastasis in renal cell carcinoma. other hsa-mir-122 Hepatitis [unspecific] 25973575 "These results demonstrate that first, exosomes mediate communication between hepatocytes and monocytes/macrophages and second, hepatocyte-derived miRNA-122 can reprogram monocytes inducing sensitization to LPS." other hsa-mir-141 "Carcinoma, Renal Cell" 25974855 "We also constructed a five-miRNAs-based classifier as a reliable prognostic and predictive tool for CSS in patients with RCC, especially in clear cell RCC (ccRCC) (HR: 5.46, 95% CI: 1.51-19.66). This method might facilitate patient counselling and individualise management of RCC." other hsa-mir-200c "Carcinoma, Renal Cell" 25974855 "We also constructed a five-miRNAs-based classifier as a reliable prognostic and predictive tool for CSS in patients with RCC, especially in clear cell RCC (ccRCC) (HR: 5.46, 95% CI: 1.51-19.66). This method might facilitate patient counselling and individualise management of RCC." other hsa-mir-21 "Carcinoma, Renal Cell" 25974855 "We also constructed a five-miRNAs-based classifier as a reliable prognostic and predictive tool for CSS in patients with RCC, especially in clear cell RCC (ccRCC) (HR: 5.46, 95% CI: 1.51-19.66). This method might facilitate patient counselling and individualise management of RCC." other hsa-mir-210 "Carcinoma, Renal Cell" 25974855 "We also constructed a five-miRNAs-based classifier as a reliable prognostic and predictive tool for CSS in patients with RCC, especially in clear cell RCC (ccRCC) (HR: 5.46, 95% CI: 1.51-19.66). This method might facilitate patient counselling and individualise management of RCC." other hsa-mir-429 "Carcinoma, Renal Cell" 25974855 "We also constructed a five-miRNAs-based classifier as a reliable prognostic and predictive tool for CSS in patients with RCC, especially in clear cell RCC (ccRCC) (HR: 5.46, 95% CI: 1.51-19.66). This method might facilitate patient counselling and individualise management of RCC." other hsa-mir-214 Bladder Neoplasms 25975233 "Urinary cell-free miR-214 is a hopeful biomarker for tumor stratification, early diagnosis and prognostic assessment of bladder cancer." other hsa-mir-21 Cardiovascular Diseases [unspecific] 25975660 miR-21 and cardiac fibrosis: another brick in the wall other hsa-mir-125a Myelodysplastic Syndromes 25976472 "In fact, regulatory factors have also been considered as miR-143/miR-145, miR-146a, miR-125a and MiR-21." other hsa-mir-1307 Colorectal Carcinoma 25977444 The polymorphic terminal-loop of pre-miR-1307 binding with MBNL1 contributes to colorectal carcinogenesis via interference with Dicer1 recruitment. other hsa-mir-17 Inflammation 25979460 Our finding that certain miRNAs may de-repress critical acute phase proteins within acute timeframes has important biological and clinical implications. other hsa-mir-18 Inflammation 25979460 Our finding that certain miRNAs may de-repress critical acute phase proteins within acute timeframes has important biological and clinical implications. other hsa-mir-19a Inflammation 25979460 Our finding that certain miRNAs may de-repress critical acute phase proteins within acute timeframes has important biological and clinical implications. other hsa-mir-19b Inflammation 25979460 Our finding that certain miRNAs may de-repress critical acute phase proteins within acute timeframes has important biological and clinical implications. other hsa-mir-19b-1 Inflammation 25979460 Our finding that certain miRNAs may de-repress critical acute phase proteins within acute timeframes has important biological and clinical implications. other hsa-mir-20a Inflammation 25979460 Our finding that certain miRNAs may de-repress critical acute phase proteins within acute timeframes has important biological and clinical implications. other hsa-mir-449c Inflammation 25979460 Our finding that certain miRNAs may de-repress critical acute phase proteins within acute timeframes has important biological and clinical implications. other hsa-mir-455 Inflammation 25979460 Our finding that certain miRNAs may de-repress critical acute phase proteins within acute timeframes has important biological and clinical implications. other hsa-mir-92-1 Inflammation 25979460 Our finding that certain miRNAs may de-repress critical acute phase proteins within acute timeframes has important biological and clinical implications. other hsa-mir-21 Neoplasms [unspecific] 25979949 Dicer1 imparts essential survival cues in Notch-driven T-ALL via miR-21-mediated tumor suppressor Pdcd4 repression. other hsa-mir-373 Prostate Neoplasms 25980442 TR4 nuclear receptor increases prostate cancer invasion via decreasing the miR-373-3p expression to alter TGF¦ÂR2/p-Smad3 signals. other hsa-mir-659 Neuroblastoma 25980492 Deregulation of focal adhesion pathway mediated by miR-659-3p is implicated in bone marrow infiltration of stage M neuroblastoma patients. other hsa-mir-140 Colorectal Carcinoma 25980495 Inhibition of colorectal cancer stem cell survival and invasive potential by hsa-miR-140-5p mediated suppression of Smad2 and autophagy. other hsa-mir-21 Atherosclerosis 25981603 miR-21 is involved in ischemic stroke pathology through atherosclerosis and provides neuroprotection by its anti-apoptotic features. other hsa-mir-210 Atherosclerosis 25981603 miR-497 induces neuronal death and miR-210 is upregulated in hypoxic cells. other hsa-mir-34b Hypoxia 25982511 "Sevoflurane preconditioning-inhibited apoptosis and preconditioning-enhanced cell viability of PC12 cells were significantly attenuated by transfection of miR-101a mimetic or miR-34b inhibitors, but were significantly enhanced by transfection of miR-34b mimetic." other hsa-mir-183 Lung Neoplasms 25983004 MiR-183 promotes growth of non-small cell lung cancer cells through FoxO1 inhibition. other hsa-mir-132 Glioma 25983322 TGF-¦Â induced miR-132 enhances the activation of TGF-¦Â signaling through inhibiting SMAD7 expression in glioma cells. other hsa-mir-215 Neoplasms [unspecific] 25984907 "This potential path highlights the crucial role of BMP2,hsa-miR-24, AP2 and MYC as the up-stream regulators of the path and hsa-miR-215 and TYMS as potential indicator of chemotherapeutic benefit in STS metastasis." other hsa-mir-24 Neoplasms [unspecific] 25984907 "This potential path highlights the crucial role of BMP2,hsa-miR-24, AP2 and MYC as the up-stream regulators of the path and hsa-miR-215 and TYMS as potential indicator of chemotherapeutic benefit in STS metastasis." other hsa-mir-126 "Diabetes Mellitus, Type 2" 25986735 Circulating miR-126 is a potential biomarker to predict the onset of type 2 diabetes mellitus in susceptible individuals. other hsa-mir-10b "Carcinoma, Lung, Non-Small-Cell" 25988292 microRNA miR-10b inhibition reduces cell proliferation and promotes apoptosis in non-small cell lung cancer (NSCLC) cells. other hsa-mir-302 Glioblastoma 25991553 Expression of the miR-302/367 cluster in glioblastoma cells suppresses tumorigenic gene expression patterns and abolishes transformation related phenotypes. other hsa-mir-367 Glioblastoma 25991553 Expression of the miR-302/367 cluster in glioblastoma cells suppresses tumorigenic gene expression patterns and abolishes transformation related phenotypes. other hsa-mir-138 Lung Neoplasms 25994569 FOXP4 modulates tumor growth and independently associates with miR-138 in non-small cell lung cancer cells. other hsa-mir-223 Inflammation 25997943 "we found that different doses of acute aerobic exercise induced a distinct and specific c-inflammamiR response, which may be associated with control of the exercise-induced inflammatory cascade. Our findings point to c-inflammamiRs as potential biomarkers of exercise-induced inflammation, and hence, exercise dose." other hsa-mir-29a Inflammation 25997943 "we found that different doses of acute aerobic exercise induced a distinct and specific c-inflammamiR response, which may be associated with control of the exercise-induced inflammatory cascade. Our findings point to c-inflammamiRs as potential biomarkers of exercise-induced inflammation, and hence, exercise dose." other hsa-mir-34a Inflammation 25997943 "we found that different doses of acute aerobic exercise induced a distinct and specific c-inflammamiR response, which may be associated with control of the exercise-induced inflammatory cascade. Our findings point to c-inflammamiRs as potential biomarkers of exercise-induced inflammation, and hence, exercise dose." other hsa-mir-424 Inflammation 25997943 "we found that different doses of acute aerobic exercise induced a distinct and specific c-inflammamiR response, which may be associated with control of the exercise-induced inflammatory cascade. Our findings point to c-inflammamiRs as potential biomarkers of exercise-induced inflammation, and hence, exercise dose." other hsa-mir-193b "Carcinoma, Hepatocellular" 25997995 miR-193b acts as a cisplatin sensitizer via the caspase-3-dependent pathway in HCC chemotherapy. other hsa-mir-126 Neoplasms [unspecific] 25999416 "This pioneering work was followed by studies that reported intercellular exchange of miRs-143/145 and miR-21* within the vascular wall and the myocardium, respectively." other hsa-mir-143 Neoplasms [unspecific] 25999416 "This pioneering work was followed by studies that reported intercellular exchange of miRs-143/145 and miR-21* within the vascular wall and the myocardium, respectively." other hsa-mir-145 Neoplasms [unspecific] 25999416 "This pioneering work was followed by studies that reported intercellular exchange of miRs-143/145 and miR-21* within the vascular wall and the myocardium, respectively." other hsa-mir-206 "Muscular Dystrophy, Duchenne" 25999854 "In contrast, local expression of mIGF-1 promotes the modulation of other microRNAs, such as miR-206 and miR-24, along with the modulation of muscle specific genes" other hsa-mir-29a Influenza 26000345 "With assay optimization, the detection limit of our MARS assay for miR-29a-3p was found to be 1 nM, and this new assay could be completed within 1 hour without thermal cycling. This non-PCR assay with high selectivity for mature microRNA provides a new platform for rapid disease diagnosis, quarantine and disease control." other hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 26001154 the MiR-205 can also increase in the case with severe inflammation and benign tumor.3 The possibility of false-positive because of noncancerous lesion has to be further studied. other hsa-mir-205 Lung Neoplasms 26001155 Reply to MiR-205 and miR-375 microRNA Assays to Distinguish Squamous Cell Carcinoma From Adenocarcinoma in Lung Cancer Biopsies. other hsa-mir-375 Lung Neoplasms 26001155 Reply to MiR-205 and miR-375 microRNA Assays to Distinguish Squamous Cell Carcinoma From Adenocarcinoma in Lung Cancer Biopsies. other hsa-mir-126 Atherosclerosis 26001902 "Conversely, CXCL12 expression can be induced by miR-126 in ECs through an auto-amplifying feedback loop to facilitate endothelial regeneration, thus limiting atherosclerosis and mediating plaque stabilization." other hsa-mir-129 Inflammatory Bowel Diseases 26003847 "TLR9 aptamers may hence potentiate miRNA regulation that enhances cholinergic signaling and the resolution of inflammation, which opens new venues for manipulating bowel diseases." other hsa-mir-186 Inflammatory Bowel Diseases 26003847 "TLR9 aptamers may hence potentiate miRNA regulation that enhances cholinergic signaling and the resolution of inflammation, which opens new venues for manipulating bowel diseases." other hsa-mir-200c Inflammatory Bowel Diseases 26003847 "TLR9 aptamers may hence potentiate miRNA regulation that enhances cholinergic signaling and the resolution of inflammation, which opens new venues for manipulating bowel diseases." other hsa-mir-338 "Squamous Cell Carcinoma, Esophageal" 26004521 MicroRNA-338-3p suppresses tumor growth of esophageal squamous cell carcinoma in vitro and in vivo. other hsa-mir-101 Neoplasms [unspecific] 26005707 "eight miRNAs including miR-17-5p, miR-20a, miR-223, miR-21, miR-155, miR-494, miR-690 and miR-101 are of particular interest regarding MDSC accumulation and function." other hsa-mir-137 Schizophrenia 26005852 The schizophrenia risk gene product miR-137 alters presynaptic plasticity. other hsa-mir-21 "Carcinoma, Thyroid, Papillary" 26007293 MiR-9 and miR-21 as prognostic biomarkers for recurrence in papillary thyroid cancer. other hsa-mir-9 "Carcinoma, Thyroid, Papillary" 26007293 MiR-9 and miR-21 as prognostic biomarkers for recurrence in papillary thyroid cancer. other hsa-mir-21 "Carcinoma, Breast" 26008976 Our data revealed tissue specific changes of extracellular circulating miRNAs that would be otherwise unraveled using blood samples. other hsa-mir-145 Gastric Neoplasms 26010149 Reverse Correlation between MicroRNA-145 and FSCN1 Affecting Gastric Cancer Migration and Invasion. other hsa-mir-21 Cervicitis 26010154 Up-Regulation of miR-21 Is Associated with Cervicitis and Human Papillomavirus Infection in Cervical Tissues. other hsa-mir-15 "Leukemia, Lymphocytic, Chronic, B-Cell" 26010203 "A rare but recurrent t(8;13)(q24;q14) translocation in B-cell chronic lymphocytic leukaemia causing MYC up-regulation and concomitant loss of PVT1, miR-15/16 and DLEU7." other hsa-mir-16 "Leukemia, Lymphocytic, Chronic, B-Cell" 26010203 "A rare but recurrent t(8;13)(q24;q14) translocation in B-cell chronic lymphocytic leukaemia causing MYC up-regulation and concomitant loss of PVT1, miR-15/16 and DLEU7." other hsa-mir-200b Lung Neoplasms 26012256 Nobiletin inhibited hypoxia-induced epithelial-mesenchymal transition of lung cancer cells by inactivating of Notch-1 signaling and switching on miR-200b. other hsa-mir-20a "Carcinoma, Colon" 26012475 The Effects of miR-20a on p21: Two Mechanisms Blocking Growth Arrest in TGF-¦Â-Responsive Colon Carcinoma. other hsa-mir-467 Breast Neoplasms 26018675 Inhibition of hyperglycemia-induced angiogenesis and breast cancer tumor growth by systemic injection of microRNA-467 antagonist. other hsa-mir-1 "Carcinoma, Hepatocellular" 26019452 "MiR-1 might be a potential tumor activator. Inhibiting its expression could decrease proliferation, induce apoptosis, and inhibit the migration and invasion of TECs of human HCC." other hsa-mir-24 Hyperglycemia 26022048 "In this issue of Blood, Xiang et al identify a novel mechanism, involving activation of the polyol pathway and repression of microRNA-24 (miR-24), through which hyperglycemia augments von Willebrand factor (VWF) expression and secretion." other hsa-mir-15b "Carcinoma, Hepatocellular" 26023735 "miR-15b-5p induces endoplasmic reticulum stress and apoptosis in human hepatocellular carcinoma, both in vitro and in vivo, by suppressing Rab1A." other hsa-mir-218 "Carcinoma, Hepatocellular" 26024833 "Hotair silence activates P16(Ink4a) and P14(ARF) signaling by enhancing miR-218 expression and suppressing Bmi-1 expression, resulting in the suppression of tumorigenesis in HCC." other hsa-mir-1202 Mandibular Prognathism 26025627 "Our results indicated a possible association between the differentially expressed miRNAs and MP pathogenesis, and the precise mechanisms are needed to be further validated." other hsa-mir-629 Mandibular Prognathism 26025627 "Our results indicated a possible association between the differentially expressed miRNAs and MP pathogenesis, and the precise mechanisms are needed to be further validated." other hsa-mir-638 Mandibular Prognathism 26025627 "Our results indicated a possible association between the differentially expressed miRNAs and MP pathogenesis, and the precise mechanisms are needed to be further validated." other hsa-mir-143 Colon Neoplasms 26025964 The data also showed that the restoration of hsa-miR-143 expression in SW480 leads to a significant translation repression of the introduced reporter and suicide genes. other hsa-mir-21 Breast Neoplasms 26026077 miR-21 is a potential biomarker for breast cancer prognosis. other hsa-mir-27 "Carcinoma, Esophageal" 26026166 miR-27 is associated with chemoresistance in esophageal cancer through transformation of normal fibroblasts to cancer-associated fibroblasts. other hsa-mir-138 Nervous System Diseases [unspecific] 26026282 "Many studies have emerged which link miRNAs with OL and myelin pathology in various central nervous system (CNS) diseases including multiple sclerosis (MS), ischemic stroke,spinal cord injury, and adult-onset autosomal dominant leukodystrophy (ADLD)." other hsa-mir-219 Nervous System Diseases [unspecific] 26026282 "Many studies have emerged which link miRNAs with OL and myelin pathology in various central nervous system (CNS) diseases including multiple sclerosis (MS), ischemic stroke,spinal cord injury, and adult-onset autosomal dominant leukodystrophy (ADLD)." other hsa-mir-338 Nervous System Diseases [unspecific] 26026282 "Many studies have emerged which link miRNAs with OL and myelin pathology in various central nervous system (CNS) diseases including multiple sclerosis (MS), ischemic stroke,spinal cord injury, and adult-onset autosomal dominant leukodystrophy (ADLD)." other hsa-mir-9 Nervous System Diseases [unspecific] 26026282 "Many studies have emerged which link miRNAs with OL and myelin pathology in various central nervous system (CNS) diseases including multiple sclerosis (MS), ischemic stroke,spinal cord injury, and adult-onset autosomal dominant leukodystrophy (ADLD)." other hsa-let-7a Lung Neoplasms 26026830 "According to our literature survey and database validation, many of these results are biologically meaningful for understanding the mechanism of the complex post-transcriptional regulations in lung cancer." other hsa-let-7b Lung Neoplasms 26026830 "According to our literature survey and database validation, many of these results are biologically meaningful for understanding the mechanism of the complex post-transcriptional regulations in lung cancer." other hsa-let-7c Lung Neoplasms 26026830 "According to our literature survey and database validation, many of these results are biologically meaningful for understanding the mechanism of the complex post-transcriptional regulations in lung cancer." other hsa-let-7f Lung Neoplasms 26026830 "According to our literature survey and database validation, many of these results are biologically meaningful for understanding the mechanism of the complex post-transcriptional regulations in lung cancer." other hsa-mir-17 Feingold Syndrome 26026879 "respectively, of miR-17-92?/+ in comparison with WT mice, thus suggesting a possible link between cognitive deficits and altered brain neurotransmission" other hsa-mir-18 Feingold Syndrome 26026879 "respectively, of miR-17-92?/+ in comparison with WT mice, thus suggesting a possible link between cognitive deficits and altered brain neurotransmission" other hsa-mir-19a Feingold Syndrome 26026879 "respectively, of miR-17-92?/+ in comparison with WT mice, thus suggesting a possible link between cognitive deficits and altered brain neurotransmission" other hsa-mir-19b-1 Feingold Syndrome 26026879 "respectively, of miR-17-92?/+ in comparison with WT mice, thus suggesting a possible link between cognitive deficits and altered brain neurotransmission" other hsa-mir-20a Feingold Syndrome 26026879 "respectively, of miR-17-92?/+ in comparison with WT mice, thus suggesting a possible link between cognitive deficits and altered brain neurotransmission" other hsa-mir-92-1 Feingold Syndrome 26026879 "respectively, of miR-17-92?/+ in comparison with WT mice, thus suggesting a possible link between cognitive deficits and altered brain neurotransmission" other hsa-mir-21 Lung Neoplasms 26026961 Nickel may contribute to EGFR mutation and synergistically promotes tumor invasion in EGFR-mutated lung cancer via nickel-induced microRNA-21 expression. other hsa-mir-125b Narcolepsy 26028057 "we would suggest the possible overexpression of these miRNAs subtypes in N1 patients close to disease onset. Yet, larger investigations are needed in the future to better determine if there is a causal association among inflammation, miRNAs, and narcolepsy." other hsa-mir-130a Narcolepsy 26028057 "we would suggest the possible overexpression of these miRNAs subtypes in N1 patients close to disease onset. Yet, larger investigations are needed in the future to better determine if there is a causal association among inflammation, miRNAs, and narcolepsy." other hsa-mir-155 Narcolepsy 26028057 "we would suggest the possible overexpression of these miRNAs subtypes in N1 patients close to disease onset. Yet, larger investigations are needed in the future to better determine if there is a causal association among inflammation, miRNAs, and narcolepsy." other hsa-mir-26a Narcolepsy 26028057 "we would suggest the possible overexpression of these miRNAs subtypes in N1 patients close to disease onset. Yet, larger investigations are needed in the future to better determine if there is a causal association among inflammation, miRNAs, and narcolepsy." other hsa-mir-30c Narcolepsy 26028057 "we would suggest the possible overexpression of these miRNAs subtypes in N1 patients close to disease onset. Yet, larger investigations are needed in the future to better determine if there is a causal association among inflammation, miRNAs, and narcolepsy." other hsa-mir-663 "Adenocarcinoma, Pancreatic Ductal" 26028359 MicroRNA-663 activates the canonical Wnt signaling through the adenomatous polyposis coli suppression. other hsa-mir-21 "Squamous Cell Carcinoma, Skin or Unspecific" 26029210 "Conversely, small HA-CD44 interaction stimulates RhoA activation, NFκB/Stat-3 signaling, and miR-21 production, resulting in inflammation and proliferation as well as SCC progression." other hsa-mir-302 Nervous System Diseases [unspecific] 26030913 These results show that neuroblasts can be generated directly from adult human and mouse astrocytes by miR-302/367-driven induction. This approach seems promising for converting glial scar cells into neuroblasts in a wide range of neurological diseases. other hsa-mir-367 Nervous System Diseases [unspecific] 26030913 These results show that neuroblasts can be generated directly from adult human and mouse astrocytes by miR-302/367-driven induction. This approach seems promising for converting glial scar cells into neuroblasts in a wide range of neurological diseases. other hsa-mir-16 Neoplasms [unspecific] 26031775 Our findings provide the first clues regarding the role of miR-16 as a tumor suppressor in cancer cells through the inhibition of FEAT translation. other hsa-mir-208 Prostate Neoplasms 26032092 Curcumin inhibits growth of prostate carcinoma via miR-208-mediated CDKN1A activation. other hsa-mir-20a Multiple Myeloma 26032093 Expressions of miR-181a and miR-20a in RPMI8226 cell line and their potential as biomarkers for multiple myeloma. other hsa-mir-200 "Diabetes Mellitus, Type 2" 26032109 Preventing ¦Â-cell apoptosis and T2DM with microRNAs--a role for miR-200 other hsa-mir-320e Colorectal Carcinoma 26035698 "In two clinical trial cohorts, a systematic biomarker discovery and validation approach identified miR-320e to be a novel prognostic biomarker that is associated with adverse clinical outcome in stage III CRC patients treated with 5-FU-based adjuvant chemotherapy. These findings have important implications for the personalised management of CRC patients." other hsa-mir-185 Pituitary Adenoma 26036598 MiR-185 enhanced the cell proliferation and inhibited the apoptosis of GH3 cells. other hsa-mir-1 "Carcinoma, Renal Cell, Clear-Cell" 26036633 MiR-1 downregulation correlates with poor survival in clear cell renal cell carcinoma where it interferes with cell cycle regulation and metastasis. other hsa-mir-323b Hepatitis B Virus Infection 26037063 The association between microRNA-323b polymorphism and hepatitis B virus persistent infection - some problems should be addressed. other hsa-mir-323b Hepatitis B Virus Infection 26037064 The association between microRNA-323b polymorphism and hepatitis B virus persistent infection - some problems should be addressed. other hsa-mir-17 "Leukemia, Myeloid, Acute" 26038136 "CDK inhibitor SNS-032 can induce apoptosis of AML HL-60 cells, which is associated with the inhibition of MCL-1,C-MYC and JAK2/STAT3, and down-regulation of miR-17-92 family." other hsa-mir-103 Myocardial Infarction 26038570 "Our results reveal a novel myocardial necrosis regulation model,which is composed of H19, miR-103/107, and FADD. Modulation of their levels may provide a new approach for preventing myocardial necrosis." other hsa-mir-107 Myocardial Infarction 26038570 "Our results reveal a novel myocardial necrosis regulation model,which is composed of H19, miR-103/107, and FADD. Modulation of their levels may provide a new approach for preventing myocardial necrosis." other hsa-mir-494 Lung Neoplasms 26040900 Tumor-derived microRNA-494 promotes angiogenesis in non-small cell lung cancer. other hsa-mir-29c Renal Fibrosis 26040904 "Overall, miR-29c correlated with the degree of renal chronicity but not with renal function, suggesting it could be used as a novel non-invasive marker of early progression to fibrosis in patients with LN." other hsa-mir-17 Leukemia 26041742 Microenvironmental interleukin-6 suppresses toll-like receptor signaling in human leukemia cells through miR-17/19A. other hsa-mir-19a Leukemia 26041742 Microenvironmental interleukin-6 suppresses toll-like receptor signaling in human leukemia cells through miR-17/19A. other hsa-mir-124 Nervous System Diseases [unspecific] 26041995 "the link between dysregulation of miR-124 and CNS disorders, such as neurodegeneration, CNS stress, neuroimmune disorders, stroke, and brain tumors, has become evident" other hsa-mir-130a "Carcinoma, Ovarian" 26043084 MiR-130a and MiR-374a Function as Novel Regulators of Cisplatin Resistance in Human Ovarian Cancer A2780 Cells. other hsa-mir-374a "Carcinoma, Ovarian" 26043084 MiR-130a and MiR-374a Function as Novel Regulators of Cisplatin Resistance in Human Ovarian Cancer A2780 Cells. other hsa-mir-449b "Carcinoma, Thyroid" 26044563 Regulation of MET-mediated proliferation of thyroid carcinoma cells by miR-449b. other hsa-mir-191 Acute Myocardial Infarction 26044724 "miR-208b was significantly increased in the AMI compared with healthy people, while miR-26a and miR-191 were decreased. miR-26a, miR-191, and miR-208b were potential indices of AMI, and miR-208b was more effective in patients with non-ST-elevation myocardial infarction." other hsa-mir-208b Acute Myocardial Infarction 26044724 "miR-208b was significantly increased in the AMI compared with healthy people, while miR-26a and miR-191 were decreased. miR-26a, miR-191, and miR-208b were potential indices of AMI, and miR-208b was more effective in patients with non-ST-elevation myocardial infarction." other hsa-mir-26a Acute Myocardial Infarction 26044724 "miR-208b was significantly increased in the AMI compared with healthy people, while miR-26a and miR-191 were decreased. miR-26a, miR-191, and miR-208b were potential indices of AMI, and miR-208b was more effective in patients with non-ST-elevation myocardial infarction." other hsa-mir-24 Gastric Neoplasms 26045155 These results suggest that the measurement of miR-24 expression from formalin-fixed paraffin-embedded (FFPE) samples is useful to identify radiation-associated GC. other hsa-mir-374b Colorectal Carcinoma 26045793 The potential value of miR-1 and miR-374b as biomarkers for colorectal cancer. other hsa-mir-27a "Carcinoma, Renal Cell, Clear-Cell" 26046464 Expression of miR-27a-3p is an independent predictive factor for recurrence in clear cell renal cell carcinoma. other hsa-mir-106b Breast Neoplasms 26046581 These observations have been validated using an independent publicly available breast cancer dataset from The Cancer Genome Atlas. other hsa-mir-148a Breast Neoplasms 26046581 These observations have been validated using an independent publicly available breast cancer dataset from The Cancer Genome Atlas. other hsa-mir-15 Breast Neoplasms 26046581 These observations have been validated using an independent publicly available breast cancer dataset from The Cancer Genome Atlas. other hsa-mir-16 Breast Neoplasms 26046581 These observations have been validated using an independent publicly available breast cancer dataset from The Cancer Genome Atlas. other hsa-mir-17 Breast Neoplasms 26046581 These observations have been validated using an independent publicly available breast cancer dataset from The Cancer Genome Atlas. other hsa-mir-18 Breast Neoplasms 26046581 These observations have been validated using an independent publicly available breast cancer dataset from The Cancer Genome Atlas. other hsa-mir-19a Breast Neoplasms 26046581 These observations have been validated using an independent publicly available breast cancer dataset from The Cancer Genome Atlas. other hsa-mir-19b-1 Breast Neoplasms 26046581 These observations have been validated using an independent publicly available breast cancer dataset from The Cancer Genome Atlas. other hsa-mir-20a Breast Neoplasms 26046581 These observations have been validated using an independent publicly available breast cancer dataset from The Cancer Genome Atlas. other hsa-mir-29a Breast Neoplasms 26046581 These observations have been validated using an independent publicly available breast cancer dataset from The Cancer Genome Atlas. other hsa-mir-29c Breast Neoplasms 26046581 These observations have been validated using an independent publicly available breast cancer dataset from The Cancer Genome Atlas. other hsa-mir-92-1 Breast Neoplasms 26046581 These observations have been validated using an independent publicly available breast cancer dataset from The Cancer Genome Atlas. other hsa-mir-21 Heart Failure 26047574 "Torasemide but not furosemide inhibits CYP11B2 activity and reduces the expression of CTGF, LOX, and miR-21." other hsa-mir-1264 Atherosclerosis 26047583 This could be a causative epigenetic mechanism associated with TNF-¦Á and IGF-1 induced smooth muscle cell proliferation involved in the pathogenesis of coronary artery hyperplasia and restenosis. other hsa-mir-126 Parkinson Disease 26047984 "Our study provides evidence for a general association of miRNAs with the cellular function and identity of SN DA neurons, and with deregulated gene expression networks and signaling pathways related to PD pathogenesis that may be sex-specific." other hsa-mir-21 "Carcinoma, Cervical" 26051842 "Overall, our study suggests that the microRNAs, miR-21 and let-7a function as clinically relevant integral components of STAT3 signaling and are responsible for maintaining activated state of STAT3 in HPV-infected cells during cervical carcinogenesis." other hsa-mir-196a Neuroendocrine Tumors 26052033 Roles of miR-196a on gene regulation of neuroendocrine tumor cells. other hsa-mir-22 Prostate Neoplasms 26052614 miR-22 and miR-29a Are Members of the Androgen Receptor Cistrome Modulating LAMC1 and Mcl-1 in Prostate Cancer. other hsa-mir-29a Prostate Neoplasms 26052614 miR-22 and miR-29a Are Members of the Androgen Receptor Cistrome Modulating LAMC1 and Mcl-1 in Prostate Cancer. other hsa-mir-32 Colorectal Carcinoma 26054686 Oridonin triggers apoptosis in colorectal carcinoma cells and suppression of microRNA-32 expression augments oridonin-mediated apoptotic effects. other hsa-mir-155 Systemic Lupus Erythematosus 26055806 "We demonstrate that SLE patients have reduced IL-21 signaling capacity, decreased miR-155 levels, and increased SOCS1 levels compared to HCs.The reduced IL-21 signaling in SLE could be rescued by overexpression of miR-155,suggesting an important role for miR-155 in the reduced IL-21 signaling observed in SLE." other hsa-mir-204 Coloboma 26056285 MiR-204 is responsible for inherited retinal dystrophy associated with ocular coloboma. other hsa-mir-30e Breast Neoplasms 26057454 We highlighted a relevant and subtype-specific role in breast cancer for miR-30e* and demonstrated that adding miRNA markers to gene signatures and clinico-pathological features can help for a better prognostication. other hsa-mir-21 "Carcinoma, Hepatocellular" 26060089 "Our results demonstrate that cisplatin inhibits the growth of HCC, possibly through the induction of G1 cell cycle arrest and apoptosis through the alteration of microRNA expression." other hsa-mir-338 "Carcinoma, Hepatocellular" 26060089 "Our results demonstrate that cisplatin inhibits the growth of HCC, possibly through the induction of G1 cell cycle arrest and apoptosis through the alteration of microRNA expression." other hsa-mir-34a "Carcinoma, Hepatocellular" 26060089 "Our results demonstrate that cisplatin inhibits the growth of HCC, possibly through the induction of G1 cell cycle arrest and apoptosis through the alteration of microRNA expression." other hsa-mir-99a "Carcinoma, Hepatocellular" 26060089 "Our results demonstrate that cisplatin inhibits the growth of HCC, possibly through the induction of G1 cell cycle arrest and apoptosis through the alteration of microRNA expression." other hsa-mir-130a Hepatitis C Virus Infection 26060358 Vitamin D Potentiates the Inhibitory Effect of MicroRNA-130a in Hepatitis C Virus Replication Independent of Type I Interferon Signaling Pathway. other hsa-mir-181c Osteosarcoma 26062442 miR-181c associates with tumor relapse of high grade osteosarcoma. other hsa-mir-217 Osteosarcoma 26062553 Quercetin Enhances Cisplatin Sensitivity of Human Osteosarcoma Cells by Modulating microRNA-217-KRAS Axis. other hsa-mir-215 "Carcinoma, Pancreatic" 26063036 miR-215 overexpression distinguishes ampullary carcinomas from pancreatic carcinomas. other hsa-mir-513c Glioblastoma 26063413 microRNA-513c suppresses the proliferation of human glioblastoma cells by repressing low-density lipoprotein receptor-related protein 6. other hsa-mir-146b Oral Lichen Planus 26064947 The TF-miRNA Coregulation Network in Oral Lichen Planus. other hsa-mir-190 Oral Lichen Planus 26064947 The TF-miRNA Coregulation Network in Oral Lichen Planus. other hsa-mir-26b Oral Lichen Planus 26064947 The TF-miRNA Coregulation Network in Oral Lichen Planus. other hsa-mir-29a Oral Lichen Planus 26064947 The TF-miRNA Coregulation Network in Oral Lichen Planus. other hsa-mir-595 Oral Lichen Planus 26064947 The TF-miRNA Coregulation Network in Oral Lichen Planus. other hsa-mir-628 Oral Lichen Planus 26064947 The TF-miRNA Coregulation Network in Oral Lichen Planus. other hsa-mir-205 Oral Leukoplakia 26064958 Identification of Gene and MicroRNA Signatures for Oral Cancer Developed from Oral Leukoplakia. other hsa-mir-21 Oral Leukoplakia 26064958 Identification of Gene and MicroRNA Signatures for Oral Cancer Developed from Oral Leukoplakia. other hsa-mir-323 Oral Leukoplakia 26064958 Identification of Gene and MicroRNA Signatures for Oral Cancer Developed from Oral Leukoplakia. other hsa-mir-423 Oral Leukoplakia 26064958 Identification of Gene and MicroRNA Signatures for Oral Cancer Developed from Oral Leukoplakia. other hsa-mir-491 Oral Leukoplakia 26064958 Identification of Gene and MicroRNA Signatures for Oral Cancer Developed from Oral Leukoplakia. other hsa-mir-499 Oral Leukoplakia 26064958 Identification of Gene and MicroRNA Signatures for Oral Cancer Developed from Oral Leukoplakia. other hsa-mir-525 Oral Leukoplakia 26064958 Identification of Gene and MicroRNA Signatures for Oral Cancer Developed from Oral Leukoplakia. other hsa-mir-549 Oral Leukoplakia 26064958 Identification of Gene and MicroRNA Signatures for Oral Cancer Developed from Oral Leukoplakia. other hsa-mir-155 "Carcinoma, Renal Cell" 26064968 miR-155 and miR-484 Are Associated with Time to Progression in Metastatic Renal Cell Carcinoma Treated with Sunitinib. other hsa-mir-484 "Carcinoma, Renal Cell" 26064968 miR-155 and miR-484 Are Associated with Time to Progression in Metastatic Renal Cell Carcinoma Treated with Sunitinib. other hsa-mir-1 Myocardial Infarction 26065643 spironolactone could increase miRNA-1 expression in ischemic rat myocardium after MI other hsa-mir-199a Colorectal Carcinoma 26065676 "It was found that miR-199a would reduce the proliferation, migration and invasion. However, overexpression of miR-199a on the apoptosis rate and cell cycles showed no significant results. The potential functionary mechanism of miR-199a might through HIF-1¦Á/VEGF pathway." other hsa-mir-27b Breast Neoplasms 26065921 Loss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1. other hsa-mir-7 Viral Infectious Disease 26067353 "Results of this study identify a molecular mechanism of RNAi for antiviral defense, and extend our knowledge of the complex interplay between host and PV, which will provide a basis for the development of effective RNAi-based therapies designed to inhibit PV replication and protect host cells." other hsa-mir-101 Prostate Neoplasms 26067553 RLIP76-dependent suppression of PI3K/AKT/Bcl-2 pathway by miR-101 induces apoptosis in prostate cancer. other hsa-mir-200 Breast Neoplasms 26068592 "The upregulation of fibronectin and lysyl oxidase directly by miR-200 or indirectly through Fli-1 or TCF12 contributed to ECM remodeling, triggering the invasion and metastasis of breast cancer cells both in vitro and vivo" other hsa-mir-205 "Adenocarcinoma, Lung" 26068980 "Surprisingly, expression of classifier miR-205 was intermediate between that of classical adenocarcinoma and squamous cell carcinoma suggesting that adenosquamous carcinoma is a transitional stage between these tumor types." other hsa-mir-200 Neoplasms [unspecific] 26069247 Network-Based Approaches to Understand the Roles of miR-200 and Other microRNAs in Cancer. other hsa-mir-184 Breast Neoplasms 26070602 These studies elucidate a new layer of regulation in the PI3K/AKT/mTOR pathway with relevance to mammary development and tumour progression and identify miR-184 as a putative breast tumour suppressor. other hsa-mir-433 Parkinson Disease 26070653 Variation in the miRNA-433 binding site of FGF20 is a risk factor for Parkinson's disease in Iranian population. other hsa-mir-101 Colorectal Carcinoma 26071354 MicroRNA-101 down-regulates sphingosine kinase 1 in colorectal cancer cells. other hsa-mir-155 Infection [unspecific] 26072128 An update on the role of miRNA-155 in pathogenic microbial infections. other hsa-mir-145 Chromosome 5q Deletion Syndrome 26075044 Loss of the microRNA genes miR-145 and miR-146a has been associated with the thrombocytosis observed in 5q- syndrome patients. other hsa-mir-146a Chromosome 5q Deletion Syndrome 26075044 Loss of the microRNA genes miR-145 and miR-146a has been associated with the thrombocytosis observed in 5q- syndrome patients. other hsa-mir-206 Lung Neoplasms 26075299 Comprehensive gene and microRNA expression profiling reveals miR-206 inhibits MET in lung cancer metastasis. other hsa-mir-150 Acute Myocardial Infarction 26077801 "Results indicated that the levels of circulating miR-486 and miR-150 are associated with AMI. They may be novel and powerful biomarkers for AMI,especially for NSTEMI." other hsa-mir-486 Acute Myocardial Infarction 26077801 "Results indicated that the levels of circulating miR-486 and miR-150 are associated with AMI. They may be novel and powerful biomarkers for AMI,especially for NSTEMI." other hsa-mir-191 Prostate Neoplasms 26078486 "Our results proved miR-191 to be the most stable gene, showing the lowest degree of variation and the highest stability value.miR-25 and SNORD48 values fell beyond the cutoff of acceptability. In conclusion,we recommend the use of miR-191 for normalization purposes in post-DRE urine sediments." other hsa-mir-25 Prostate Neoplasms 26078486 "Our results proved miR-191 to be the most stable gene, showing the lowest degree of variation and the highest stability value.miR-25 and SNORD48 values fell beyond the cutoff of acceptability. In conclusion,we recommend the use of miR-191 for normalization purposes in post-DRE urine sediments." other hsa-mir-210 Lung Disease [unspecific] 26079696 this study demonstrates the added value of an integrated miRNA-mRNA approach for identifying molecular events altered by environmental pollutants in an in vitro human model. other hsa-let-7 Neoplasms [unspecific] 26080928 these results suggest that cytoplasmic uridylation pathway actively participates in blockade of let-7 biogenesis by Lin28B. other hsa-mir-184 Hepatoblastoma 26081234 miRNA-184 lentivirus-mediated human lens epithelial cells (HLEC) can inhibit the occurrence of epithelial-mesenchymal transition (EMT). other hsa-mir-222 Inflammation 26081516 "In pathological hyperglycaemic conditions, EMP-mediated miR-222-dependent anti-inflammatory effects are reduced." other hsa-mir-449a Prostate Neoplasms 26081756 Capsaicin causes inactivation and degradation of the androgen receptor by inducing the restoration of miR-449a in prostate cancer. other hsa-mir-337 Neuroblastoma 26084291 miRNA-337-3p suppresses neuroblastoma progression by repressing the transcription of matrix metalloproteinase 14. other hsa-mir-223 Pulmonary Hypertension 26084306 miR-223 reverses experimental pulmonary arterial hypertension. other hsa-mir-502 Colorectal Carcinoma 26086375 "While the approach is here validated for CRC, the implementation of disease-specific miRNA target prediction algorithms can be easily adopted for other applications too. The identification of disease-specific miRNA target interactions may also facilitate the identification of potential drug targets." other hsa-mir-650 Colorectal Carcinoma 26086375 "While the approach is here validated for CRC, the implementation of disease-specific miRNA target prediction algorithms can be easily adopted for other applications too. The identification of disease-specific miRNA target interactions may also facilitate the identification of potential drug targets." other hsa-mir-7 Colorectal Carcinoma 26086375 "While the approach is here validated for CRC, the implementation of disease-specific miRNA target prediction algorithms can be easily adopted for other applications too. The identification of disease-specific miRNA target interactions may also facilitate the identification of potential drug targets." other hsa-mir-760 Colorectal Carcinoma 26086375 "While the approach is here validated for CRC, the implementation of disease-specific miRNA target prediction algorithms can be easily adopted for other applications too. The identification of disease-specific miRNA target interactions may also facilitate the identification of potential drug targets." other hsa-mir-93 Colorectal Carcinoma 26086375 "While the approach is here validated for CRC, the implementation of disease-specific miRNA target prediction algorithms can be easily adopted for other applications too. The identification of disease-specific miRNA target interactions may also facilitate the identification of potential drug targets." other hsa-mir-101 Inflammation 26087518 "Advances in understanding the roles of microRNA-101 in inflammation, fibrosis and cancer" other hsa-mir-93 "Carcinoma, Ovarian" 26087719 The results suggested that berberine modulated the sensitivity of cisplatin through miR-93/PTEN/AKT signaling pathway in the ovarian cancer cells. other hsa-mir-22 Inflammation 26088024 extracellular Adenosine and uridine triphosphate (ATP and UTP) can attenuate ICAM-1 expression and leukocyte adhesion in endothelial cells through miR-22. other hsa-mir-200a Breast Neoplasms 26088362 miR-200a inhibits migration of triple-negative breast cancer cells through direct repression of the EPHA2 oncogene. other hsa-mir-133a Prostate Neoplasms 26089375 "Our data suggest that AA-specific/-enriched miRNA-mRNA pairings may play a critical role in the activation of oncogenic pathways in AA prostate cancer. Our findings also suggest that miR-133a/MCL1, miR-513c/STAT1, and miR-96/FOXO3A may have clinical significance in the development of novel strategies for treating aggressive prostate cancer." other hsa-mir-145 Prostate Neoplasms 26089375 "Our data suggest that AA-specific/-enriched miRNA-mRNA pairings may play a critical role in the activation of oncogenic pathways in AA prostate cancer. Our findings also suggest that miR-133a/MCL1, miR-513c/STAT1, and miR-96/FOXO3A may have clinical significance in the development of novel strategies for treating aggressive prostate cancer." other hsa-mir-34a Prostate Neoplasms 26089375 "Our data suggest that AA-specific/-enriched miRNA-mRNA pairings may play a critical role in the activation of oncogenic pathways in AA prostate cancer. Our findings also suggest that miR-133a/MCL1, miR-513c/STAT1, and miR-96/FOXO3A may have clinical significance in the development of novel strategies for treating aggressive prostate cancer." other hsa-mir-513c Prostate Neoplasms 26089375 "Our data suggest that AA-specific/-enriched miRNA-mRNA pairings may play a critical role in the activation of oncogenic pathways in AA prostate cancer. Our findings also suggest that miR-133a/MCL1, miR-513c/STAT1, and miR-96/FOXO3A may have clinical significance in the development of novel strategies for treating aggressive prostate cancer." other hsa-mir-96 Prostate Neoplasms 26089375 "Our data suggest that AA-specific/-enriched miRNA-mRNA pairings may play a critical role in the activation of oncogenic pathways in AA prostate cancer. Our findings also suggest that miR-133a/MCL1, miR-513c/STAT1, and miR-96/FOXO3A may have clinical significance in the development of novel strategies for treating aggressive prostate cancer." other hsa-mir-9 "Lymphoma, Hodgkin" 26089393 We report a high-resolution time series study of transcriptome dynamics following antimiR-mediated inhibition of miR-9 in a Hodgkin lymphoma cell-line-the first such dynamic study of the microRNA inhibition response-revealing both general and specific aspects of the physiological response. other hsa-mir-221 Hepatitis C Virus Infection 26090579 IFN-¦Á-Induced Downregulation of miR-221 in Dendritic Cells: Implications for HCV Pathogenesis and Treatment. other hsa-mir-34a Toxic Encephalopathy 26091620 We also found that inhibition of astrocytic miR-34a after Lipopolysaccharide(LPS) stimulation can postpone dopaminergic neuron loss under neurotoxin stress. other hsa-mir-29 Pancreatic Neoplasms 26095125 Pathophysiological role of microRNA-29 in pancreatic cancer stroma. other hsa-mir-146a Breast Neoplasms 26095299 "our study provided new insights into the function of CXCR4 in breast cancer: it promotes tumor progression as both a protein-coding gene and a non-coding RNA, complicating the mechanism by which oncogenes promote tumor progression." other hsa-mir-137 Intellectual Disability 26095359 "Our findings suggest that miR-137 is a key factor in the control of synaptic efficacy and mGluR-dependent synaptic plasticity, supporting the notion that glutamatergic dysfunction contributes to the pathogenesis of miR-137-linked cognitive impairments." other hsa-mir-150 Myasthenia Gravis 26095457 "The immuno-microRNAs miR-150-5p and miR-21-5p show a disease specific signature, which suggests these microRNAs as possible biological autoimmune markers of myasthenia gravis (MG)." other hsa-mir-21 Myasthenia Gravis 26095457 "The immuno-microRNAs miR-150-5p and miR-21-5p show a disease specific signature, which suggests these microRNAs as possible biological autoimmune markers of myasthenia gravis (MG)." other hsa-mir-122 Hepatitis C Virus Infection 26096908 Hepatitis C virus addiction to liver miR-122 takes its Toll on the host. other hsa-mir-29b Spinal Cord Injuries 26097563 Combinatorial effects of miR-20a and miR-29b on neuronal apoptosis induced by spinal cord injury. other hsa-mir-196a "Carcinoma, Ovarian" 26097603 "In conclusion, miR-196a may play an important role in the progression of ovarian carcinoma, and could be used as an independent prognostic biomarker for patients with ovarian carcinoma." other hsa-mir-19 Lung Neoplasms 26098000 MicroRNA-19 triggers epithelial-mesenchymal transition of lung cancer cells accompanied by growth inhibition. other hsa-mir-21 Neoplasms [unspecific] 26101800 The IL-6/STAT3 pathway via miR-21 is involved in the neoplastic and metastatic properties of arsenite-transformed human keratinocytes. other hsa-mir-21 Breast Neoplasms 26106867 Successful attempts were made in applying the approach to detect miR-21 in human cell lysate samples of breast cancer patients. other hsa-mir-26a Obesity 26107166 These results unravel a new mechanism by which bile acid receptor TGR5 activates a miRNA gene expression. other hsa-mir-133a Breast Neoplasms 26107945 MiR-133a Is Functionally Involved in Doxorubicin-Resistance in Breast Cancer Cells MCF-7 via Its Regulation of the Expression of Uncoupling Protein 2. other hsa-mir-7 Lung Neoplasms 26108539 miR-7 modulates chemoresistance of small cell lung cancer by repressing MRP1/ABCC1. other hsa-mir-21 Glioma 26109525 Tamoxifen-Induced Cell Death of Malignant Glioma Cells Is Brought About by Oxidative-Stress-Mediated Alterations in the Expression of BCL2 Family Members and Is Enhanced on miR-21 Inhibition. other hsa-mir-23a Prostate Neoplasms 26110567 "By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer." other hsa-mir-218 Neoplasms [unspecific] 26111662 Opposite effects of two estrogen receptors on tau phosphorylation through disparate effects on the miR-218/PTPA pathway. other hsa-mir-148a Osteosarcoma 26111756 Bufalin Inhibits the Differentiation and Proliferation of Cancer Stem Cells Derived from Primary Osteosarcoma Cells through Mir-148a. other hsa-mir-22 Liver Cirrhosis 26112332 MiR-22 promotes the development of cirrhosis through BMP7 suppression. other hsa-mir-33a "Carcinoma, Pancreatic" 26113407 miR-33a suppresses the nuclear translocation of ¦Â-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells. other hsa-mir-146a Coronary Artery Disease 26114385 Meta-Analysis of miR-146a Polymorphisms Association with Coronary Artery Diseases and Ischemic Stroke. other hsa-mir-21 Lymphoma 26116372 MiR-21: an environmental driver of malignant melanoma other hsa-mir-153 Parkinson Disease 26116522 Tanshinone IIA protects dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity through miR-153/NF-E2-related factor 2/antioxidant response element signaling pathway. other hsa-mir-21 "Leukemia, Myelogenous, Chronic, BCR-ABL Positive" 26116834 Curcumin inhibits in vitro and in vivo chronic myelogenous leukemia cells growth:a possible role for exosomal disposal of miR-21. other hsa-mir-17 Neoplasms [unspecific] 26117336 Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis. other hsa-mir-20a Neoplasms [unspecific] 26117336 Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis. other hsa-let-7c Pancreatic Neoplasms 26121640 "Our novel findings indicate that salivary miRNA are discriminatory in pancreatic cancer patients that are not eligible for surgery. In addition, we demonstrate in experimental models that salivary miRNA detection precedes systemic detection of cancer cells markers. This study stems for the use of salivary miRNA as biomarker for the early diagnosis of patients with unresectable pancreatic cancer." other hsa-mir-21 Pancreatic Neoplasms 26121640 "Our novel findings indicate that salivary miRNA are discriminatory in pancreatic cancer patients that are not eligible for surgery. In addition, we demonstrate in experimental models that salivary miRNA detection precedes systemic detection of cancer cells markers. This study stems for the use of salivary miRNA as biomarker for the early diagnosis of patients with unresectable pancreatic cancer." other hsa-mir-210 Pancreatic Neoplasms 26121640 "Our novel findings indicate that salivary miRNA are discriminatory in pancreatic cancer patients that are not eligible for surgery. In addition, we demonstrate in experimental models that salivary miRNA detection precedes systemic detection of cancer cells markers. This study stems for the use of salivary miRNA as biomarker for the early diagnosis of patients with unresectable pancreatic cancer." other hsa-mir-216 Pancreatic Neoplasms 26121640 "Our novel findings indicate that salivary miRNA are discriminatory in pancreatic cancer patients that are not eligible for surgery. In addition, we demonstrate in experimental models that salivary miRNA detection precedes systemic detection of cancer cells markers. This study stems for the use of salivary miRNA as biomarker for the early diagnosis of patients with unresectable pancreatic cancer." other hsa-mir-23a Pancreatic Neoplasms 26121640 "Our novel findings indicate that salivary miRNA are discriminatory in pancreatic cancer patients that are not eligible for surgery. In addition, we demonstrate in experimental models that salivary miRNA detection precedes systemic detection of cancer cells markers. This study stems for the use of salivary miRNA as biomarker for the early diagnosis of patients with unresectable pancreatic cancer." other hsa-mir-23b Pancreatic Neoplasms 26121640 "Our novel findings indicate that salivary miRNA are discriminatory in pancreatic cancer patients that are not eligible for surgery. In addition, we demonstrate in experimental models that salivary miRNA detection precedes systemic detection of cancer cells markers. This study stems for the use of salivary miRNA as biomarker for the early diagnosis of patients with unresectable pancreatic cancer." other hsa-mir-29c Pancreatic Neoplasms 26121640 "Our novel findings indicate that salivary miRNA are discriminatory in pancreatic cancer patients that are not eligible for surgery. In addition, we demonstrate in experimental models that salivary miRNA detection precedes systemic detection of cancer cells markers. This study stems for the use of salivary miRNA as biomarker for the early diagnosis of patients with unresectable pancreatic cancer." other hsa-mir-132 Wounds and Injuries [unspecific] 26121747 MicroRNA-132 enhances transition from inflammation to proliferation during wound healing. other hsa-mir-21 Glioma 26121981 DEAD-box RNA helicase DDX23 modulates glioma malignancy via elevating miR-21 biogenesis. other hsa-mir-373 Breast Neoplasms 26122224 INFLUENCE OF miR-373 ON THE INVASION AND MIGRATION OF BREAST CANCER AND THE EXPRESSION LEVEL OF TARGET GENES TXNIP. other hsa-mir-148a Neoplasms [unspecific] 26124099 MicroRNA-148a reduces tumorigenesis and increases TRAIL-induced apoptosis in NSCLC. other hsa-mir-193a Pleural Mesothelioma 26125439 miR-193a-3p is a potential tumor suppressor in malignant pleural mesothelioma. other hsa-mir-21 "Carcinoma, Esophageal" 26125864 Association of miR-21 with esophageal cancer prognosis: a meta-analysis. other hsa-mir-182 "Carcinoma, Hepatocellular" 26126858 Our data showed that hypoxia regulated the expression of miR-182 and RASA1 to promote HCC angiogenesis. other hsa-mir-125a Breast Neoplasms 26130254 "Relative levels of let-7a, miR-17, miR-27b, miR-125a, miR-125b and miR-206 as potential molecular markers to evaluate grade, receptor status and molecular type in breast cancer." other hsa-mir-125b Breast Neoplasms 26130254 "Relative levels of let-7a, miR-17, miR-27b, miR-125a, miR-125b and miR-206 as potential molecular markers to evaluate grade, receptor status and molecular type in breast cancer." other hsa-mir-17 Breast Neoplasms 26130254 "Relative levels of let-7a, miR-17, miR-27b, miR-125a, miR-125b and miR-206 as potential molecular markers to evaluate grade, receptor status and molecular type in breast cancer." other hsa-mir-206 Breast Neoplasms 26130254 "Relative levels of let-7a, miR-17, miR-27b, miR-125a, miR-125b and miR-206 as potential molecular markers to evaluate grade, receptor status and molecular type in breast cancer." other hsa-mir-27b Breast Neoplasms 26130254 "Relative levels of let-7a, miR-17, miR-27b, miR-125a, miR-125b and miR-206 as potential molecular markers to evaluate grade, receptor status and molecular type in breast cancer." other hsa-mir-203 "Carcinoma, Lung" 26132195 miR-203 Inhibits Frizzled-2 Expression via CD82/KAI1 Expression in Human Lung Carcinoma Cells. other hsa-mir-100 Colorectal Carcinoma 26132860 These findings suggest that extracellular miRNAs can function in target cells and uncover a potential new mode of action for mutant KRAS in CRC. other hsa-mir-216a Pancreatic Neoplasms 26134156 MicroRNA-216a enhances the radiosensitivity of pancreatic cancer cells by inhibiting beclin-1-mediated autophagy. other hsa-mir-21 Lung Neoplasms 26134223 A prognostic classifier comprising three types of genomic and epigenomic data may help guide the postoperative management of stage I lung cancer patients at high risk of recurrence. other hsa-mir-17 Coronary Artery Disease 26134369 MiR-17-5p as circulating biomarkers for the severity of coronary atherosclerosis in coronary artery disease. other hsa-mir-222 Intervertebral Disc Degeneration 26134418 "a comprehensive microRNA-222 and microRNA-589 gene regulatory network was constructed, which was found to be important in IDD progression." other hsa-mir-589 Intervertebral Disc Degeneration 26134418 "a comprehensive microRNA-222 and microRNA-589 gene regulatory network was constructed, which was found to be important in IDD progression." other hsa-mir-204 Glioma 26134825 "Decreased Expression of MiRNA-204-5p Contributes to Glioma Progression and Promotes Glioma Cell Growth, Migration and Invasion." other hsa-mir-135 Glomerulonephritis 26134897 miR-135 family members mediate podocyte injury through the activation of Wnt/¦Â-catenin signaling. other hsa-mir-152 "Carcinoma, Nasopharyngeal" 26135619 Our findings provide new insights into the metastasis of NPC regulated by EBV and advocate for developing clinical intervention strategies against NPC. other hsa-mir-195 "Carcinoma, Nasopharyngeal" 26135619 Our findings provide new insights into the metastasis of NPC regulated by EBV and advocate for developing clinical intervention strategies against NPC. other hsa-mir-138 Costello Syndrome 26138095 "These results allow us to conclude that the H-Ras G12S mutation plays an important role in miRNA expression and open up a new line of study to understand the consequences of this mutation on Costello syndrome. Furthermore,they suggest that oncogenes may have a sufficiently important impact on miRNA expression to promote the development of numerous cancers." other hsa-mir-138 Neoplasms [unspecific] 26138095 "These results allow us to conclude that the H-Ras G12S mutation plays an important role in miRNA expression and open up a new line of study to understand the consequences of this mutation on Costello syndrome. Furthermore,they suggest that oncogenes may have a sufficiently important impact on miRNA expression to promote the development of numerous cancers." other hsa-mir-206 Costello Syndrome 26138095 "These results allow us to conclude that the H-Ras G12S mutation plays an important role in miRNA expression and open up a new line of study to understand the consequences of this mutation on Costello syndrome. Furthermore,they suggest that oncogenes may have a sufficiently important impact on miRNA expression to promote the development of numerous cancers." other hsa-mir-206 Neoplasms [unspecific] 26138095 "These results allow us to conclude that the H-Ras G12S mutation plays an important role in miRNA expression and open up a new line of study to understand the consequences of this mutation on Costello syndrome. Furthermore,they suggest that oncogenes may have a sufficiently important impact on miRNA expression to promote the development of numerous cancers." other hsa-mir-330 Costello Syndrome 26138095 "These results allow us to conclude that the H-Ras G12S mutation plays an important role in miRNA expression and open up a new line of study to understand the consequences of this mutation on Costello syndrome. Furthermore,they suggest that oncogenes may have a sufficiently important impact on miRNA expression to promote the development of numerous cancers." other hsa-mir-330 Neoplasms [unspecific] 26138095 "These results allow us to conclude that the H-Ras G12S mutation plays an important role in miRNA expression and open up a new line of study to understand the consequences of this mutation on Costello syndrome. Furthermore,they suggest that oncogenes may have a sufficiently important impact on miRNA expression to promote the development of numerous cancers." other hsa-mir-342 Costello Syndrome 26138095 "These results allow us to conclude that the H-Ras G12S mutation plays an important role in miRNA expression and open up a new line of study to understand the consequences of this mutation on Costello syndrome. Furthermore,they suggest that oncogenes may have a sufficiently important impact on miRNA expression to promote the development of numerous cancers." other hsa-mir-342 Neoplasms [unspecific] 26138095 "These results allow us to conclude that the H-Ras G12S mutation plays an important role in miRNA expression and open up a new line of study to understand the consequences of this mutation on Costello syndrome. Furthermore,they suggest that oncogenes may have a sufficiently important impact on miRNA expression to promote the development of numerous cancers." other hsa-mir-99b Costello Syndrome 26138095 "These results allow us to conclude that the H-Ras G12S mutation plays an important role in miRNA expression and open up a new line of study to understand the consequences of this mutation on Costello syndrome. Furthermore,they suggest that oncogenes may have a sufficiently important impact on miRNA expression to promote the development of numerous cancers." other hsa-mir-99b Neoplasms [unspecific] 26138095 "These results allow us to conclude that the H-Ras G12S mutation plays an important role in miRNA expression and open up a new line of study to understand the consequences of this mutation on Costello syndrome. Furthermore,they suggest that oncogenes may have a sufficiently important impact on miRNA expression to promote the development of numerous cancers." other hsa-mir-31 Psoriasis 26138368 NF-¦ÊB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis. other hsa-mir-125b Neoplasms [unspecific] 26138442 MAP3K11 might function as an important tumor suppressor neutralized by oncomiR-125b in B-cell leukemia. other hsa-mir-133 Glioblastoma 26138587 Growth of glioblastoma is inhibited by miR-133-mediated EGFR suppression. other hsa-mir-449c "Carcinoma, Gastric" 26141986 MiR-449c inhibits gastric carcinoma growth. other hsa-mir-101 Neoplasms [unspecific] 26145175 MicroRNA-101 Suppresses Tumor Cell Proliferation by Acting as an Endogenous Proteasome Inhibitor via Targeting the Proteasome Assembly Factor POMP. other hsa-mir-194 Lymphoma 26147452 modulation of microRNA-194 may constitute a novel approach to inhibiting proliferation of EBV(+) B cell lymphomas in PTLD. other hsa-mir-15a Colorectal Adenoma 26148070 Oncogenic Role of miR-15a-3p in 13q Amplicon-Driven Colorectal Adenoma-to-Carcinoma Progression. other hsa-mir-125a Obesity 26148871 miR-125a-3p and miR-483-5p promote adipogenesis via suppressing the RhoA/ROCK1/ERK1/2 pathway in multiple symmetric lipomatosis. other hsa-mir-483 Obesity 26148871 miR-125a-3p and miR-483-5p promote adipogenesis via suppressing the RhoA/ROCK1/ERK1/2 pathway in multiple symmetric lipomatosis. other hsa-mir-150 Influenza 26148929 The up-regulation of miR-150 is associated with poorer outcomes of A/H1N1 infection. The differential expression of miRNAs related with immune processes in severe A/H1N1 disease supports the potential role of these miRNAs as biomarkers of disease progression. other hsa-mir-107 Glaucoma 26149270 "Experimental evidences indicate that the uveoscleral pathway, via suprachoroidal space, can provide a potential route of access from the anterior region to the posterior segment of the eye and could represent the path followed by biologic mediators to reach the inner layer of the peripapillary retina and transmit damage signals from the anterior to posterior segment during glaucoma course." other hsa-mir-149 Glaucoma 26149270 "Experimental evidences indicate that the uveoscleral pathway, via suprachoroidal space, can provide a potential route of access from the anterior region to the posterior segment of the eye and could represent the path followed by biologic mediators to reach the inner layer of the peripapillary retina and transmit damage signals from the anterior to posterior segment during glaucoma course." other hsa-mir-21 Glaucoma 26149270 "Experimental evidences indicate that the uveoscleral pathway, via suprachoroidal space, can provide a potential route of access from the anterior region to the posterior segment of the eye and could represent the path followed by biologic mediators to reach the inner layer of the peripapillary retina and transmit damage signals from the anterior to posterior segment during glaucoma course." other hsa-mir-450 Glaucoma 26149270 "Experimental evidences indicate that the uveoscleral pathway, via suprachoroidal space, can provide a potential route of access from the anterior region to the posterior segment of the eye and could represent the path followed by biologic mediators to reach the inner layer of the peripapillary retina and transmit damage signals from the anterior to posterior segment during glaucoma course." other hsa-mir-21 Lymphoma 26150475 Expression and clinicopathological significance of microRNA-21 and programmed cell death 4 in malignant melanoma. other hsa-mir-1181 Ovarian Neoplasms 26151663 Activation of ARK5/miR-1181/HOXA10 axis promotes epithelial-mesenchymal transition in ovarian cancer. other hsa-mir-133a Rhabdomyosarcoma 26153023 "ARS treatment in ERMS cells ROS-dependently induces the expression of the myo-miRs, miR-133a and miR-206, which are down-regulated in RMS, and reduces PAX7 protein levels." other hsa-mir-126 Lung Neoplasms 26156018 most analyzed miRNA genes undergo substantial copy number alteration in lung cancer. other hsa-mir-155 Lung Neoplasms 26156018 most analyzed miRNA genes undergo substantial copy number alteration in lung cancer. other hsa-mir-17 Lung Neoplasms 26156018 most analyzed miRNA genes undergo substantial copy number alteration in lung cancer. other hsa-mir-205 Lung Neoplasms 26156018 most analyzed miRNA genes undergo substantial copy number alteration in lung cancer. other hsa-mir-21 Lung Neoplasms 26156018 "The most frequently amplified miRNA genes include the following: miR-30d, miR-21, miR-17 and miR-155." other hsa-mir-30a Lung Neoplasms 26156018 "The most frequently amplified miRNA genes include the following: miR-30d, miR-21, miR-17 and miR-155." other hsa-mir-30d Lung Neoplasms 26156018 "The most frequently amplified miRNA genes include the following: miR-30d, miR-21, miR-17 and miR-155." other hsa-mir-31 Lung Neoplasms 26156018 most analyzed miRNA genes undergo substantial copy number alteration in lung cancer. other hsa-mir-92 Lung Neoplasms 26156018 most analyzed miRNA genes undergo substantial copy number alteration in lung cancer. other hsa-mir-21 Neoplasms [unspecific] 26156753 "This is the first study to demonstrate that kallistatin's heparin-binding site is crucial for preventing TGF-¦Â-induced miR-21 and oxidative stress, while its active site is key for stimulating the expression of antioxidant genes via interaction with an endothelial surface tyrosine kinase.These findings reveal novel mechanisms of kallistatin in protection against fibrosis and cancer by suppressing EndMT." other hsa-mir-145 "Carcinoma, Esophageal" 26156802 The effect of recombinant lentiviral vector encoding miR-145 on human esophageal cancer cells. other hsa-mir-146a "Squamous Cell Carcinoma, Oral" 26159827 Decrease of miR-146a is associated with the aggressiveness of human oral squamous cell carcinoma. other hsa-mir-23a Osteosarcoma 26160225 MicroRNA-23a enhances migration and invasion through PTEN in osteosarcoma. other hsa-mir-323 Prostate Neoplasms 26160610 Our data demonstrate that miR-323 may increase VEGF-A-mediated cancer vascularization in PC cells through AdipoR1 suppression. other hsa-mir-451a Breast Neoplasms 26161389 miR-451a Inhibited Cell Proliferation and Enhanced Tamoxifen Sensitive in Breast Cancer via Macrophage Migration Inhibitory Factor. other hsa-let-7b Influenza 26163223 These results indicate that the influenza virus containing microRNA response elements (MREs) is attenuated in vivo and can be used to design a live attenuated vaccine. other hsa-mir-502 "Carcinoma, Hepatocellular" 26163264 miR-502 inhibits cell proliferation and tumor growth in hepatocellular carcinoma through suppressing phosphoinositide 3-kinase catalytic subunit gamma. other hsa-mir-376c Prostate Neoplasms 26163549 Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines. other hsa-mir-223 "Leukemia, Myeloid, Acute" 26163797 MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia. other hsa-mir-141 Breast Neoplasms 26164002 miR-141 as potential suppressor of ¦Â-catenin in breast cancer. other hsa-mir-451 "Carcinoma, Hepatocellular" 26164082 MicroRNA-451: epithelial-mesenchymal transition inhibitor and prognostic biomarker of hepatocelluar carcinoma. other hsa-mir-31 Glioblastoma 26164206 Loss of tumor suppressive microRNA-31 enhances TRADD/NF-¦ÊB signaling in glioblastoma. other hsa-mir-221 Prostate Neoplasms 26164758 Effects of microRNA-221/222 on cell proliferation and apoptosis in prostate cancer cells. other hsa-mir-222 Prostate Neoplasms 26164758 Effects of microRNA-221/222 on cell proliferation and apoptosis in prostate cancer cells. other hsa-mir-146 Cardiometabolic Disorders 26165231 Post-Transcriptional Regulation of Renalase Gene by miR-29 and miR-146 MicroRNAs:Implications for Cardiometabolic Disorders. other hsa-mir-29 Cardiometabolic Disorders 26165231 Post-Transcriptional Regulation of Renalase Gene by miR-29 and miR-146 MicroRNAs:Implications for Cardiometabolic Disorders. other hsa-mir-139 "Leukemia, Myeloid" 26165837 miR-139-5p controls translation in myeloid leukemia through EIF4G2. other hsa-mir-15b Pancreatic Neoplasms 26166038 miR-15b promotes epithelial-mesenchymal transition by inhibiting SMURF2 in pancreatic cancer. other hsa-mir-324 Breast Neoplasms 26166821 Sinomenine inhibits breast cancer cell invasion and migration by suppressing NF-¦ÊB activation mediated by IL-4/miR-324-5p/CUEDC2 axis. other hsa-mir-21 Ischemia-Reperfusion Injury 26168042 "losartan treatment significantly increased microRNA (miR)-1, -15b, -92a, -133a, -133b, -210, and -499 expression but decreased miR-21 in the left ventricle." other hsa-mir-21 Myocardial Infarction 26168042 "losartan treatment significantly increased microRNA (miR)-1, -15b, -92a, -133a, -133b, -210, and -499 expression but decreased miR-21 in the left ventricle." other hsa-mir-145 Neoplasms [unspecific] 26168819 "Treatments of T-CIN+ cells with senescence-conditioned media induce sphere formation exclusively in cells with senescence-associated tumorigenicity, a capacity that depends on miR-145 repression." other hsa-mir-125b Glioma 26170223 PI3K inhibitor combined with miR-125b inhibitor sensitize TMZ-induced anti-glioma stem cancer effects through inactivation of Wnt/¦Â-catenin signaling pathway. other hsa-mir-183 Non-Sensory Diseases 26170234 the genomic organization and seeming redundancy of the miR-183 family cluster was conserved through 600 million years of evolution other hsa-mir-150 Neoplasms [unspecific] 26170969 iR-150 may be a potential biomarker and therapeutic target in the diagnosis and treatment of various malignancies. other hsa-mir-27a Sepsis 26171875 "RhTNFR:Fc improved cardiac function of sepsis mice, and markedly decreased miR-27a but increased Nrf2 expression level of myocardium in LPS treated mice." other hsa-mir-375 "Squamous Cell Carcinoma, Head and Neck" 26172508 MicroRNA-375 Suppresses Extracellular Matrix Degradation and Invadopodial Activity in Head and Neck Squamous Cell Carcinoma. other hsa-mir-31 Early-Stage Colon Carcinoma 26173758 The potential role of microRNA-31 expression in early colorectal cancer. other hsa-mir-1246 Hemophilia A 26176629 Small ncRNA Expression-Profiling of Blood from Hemophilia A Patients Identifies miR-1246 as a Potential Regulator of Factor 8 Gene. other hsa-mir-30a Atherosclerosis 26176854 "we here report the successful use of miRNA technology to silence a platelet protein in megakaryoblastic cells and demonstrate its usefulness in functional assays. Hence, we believe that artificial miRNAs are suitable tools to unravel the role of a protein of interest in stem cells, megakaryocytes and platelets, thereby expanding their application to novel fields of basic and translational research." other hsa-mir-155 Melanoma 26176991 "hsa-mir-214-3p, hsa-miR-199a-3p,hsa-miR-155-5p in subsets of EVs released by melanoma cells, with significant similarities to clinical melanoma tissue, and provides unique insights into the contribution of EV associated extracellular RNA in cancer." other hsa-mir-199a Melanoma 26176991 "hsa-mir-214-3p, hsa-miR-199a-3p,hsa-miR-155-5p in subsets of EVs released by melanoma cells, with significant similarities to clinical melanoma tissue, and provides unique insights into the contribution of EV associated extracellular RNA in cancer." other hsa-mir-214 Melanoma 26176991 "hsa-mir-214-3p, hsa-miR-199a-3p,hsa-miR-155-5p in subsets of EVs released by melanoma cells, with significant similarities to clinical melanoma tissue, and provides unique insights into the contribution of EV associated extracellular RNA in cancer." other hsa-mir-135b Colorectal Carcinoma 26178670 miR-135b and miR-146b-dependent silencing of calcium-sensing receptor expression in colorectal tumors. other hsa-mir-146b Colorectal Carcinoma 26178670 miR-135b and miR-146b-dependent silencing of calcium-sensing receptor expression in colorectal tumors. other hsa-mir-27a Colorectal Carcinoma 26178670 miR-135b and miR-146b-dependent silencing of calcium-sensing receptor expression in colorectal tumors. other hsa-mir-9 Colorectal Carcinoma 26178670 miR-135b and miR-146b-dependent silencing of calcium-sensing receptor expression in colorectal tumors. other hsa-let-7 Breast Neoplasms 26178901 "The most abundant exosome microRNAs (let-7a, miR-23b, miR-27a/b, miR-21, let-7, and miR-320b) are known to have anti-cancer and/or anti-angiogenic activity." other hsa-let-7a Breast Neoplasms 26178901 "The most abundant exosome microRNAs (let-7a, miR-23b, miR-27a/b, miR-21, let-7, and miR-320b) are known to have anti-cancer and/or anti-angiogenic activity." other hsa-mir-21 Breast Neoplasms 26178901 "The most abundant exosome microRNAs (let-7a, miR-23b, miR-27a/b, miR-21, let-7, and miR-320b) are known to have anti-cancer and/or anti-angiogenic activity." other hsa-mir-23b Breast Neoplasms 26178901 "The most abundant exosome microRNAs (let-7a, miR-23b, miR-27a/b, miR-21, let-7, and miR-320b) are known to have anti-cancer and/or anti-angiogenic activity." other hsa-mir-27a Breast Neoplasms 26178901 "The most abundant exosome microRNAs (let-7a, miR-23b, miR-27a/b, miR-21, let-7, and miR-320b) are known to have anti-cancer and/or anti-angiogenic activity." other hsa-mir-27b Breast Neoplasms 26178901 "The most abundant exosome microRNAs (let-7a, miR-23b, miR-27a/b, miR-21, let-7, and miR-320b) are known to have anti-cancer and/or anti-angiogenic activity." other hsa-mir-320b Breast Neoplasms 26178901 "The most abundant exosome microRNAs (let-7a, miR-23b, miR-27a/b, miR-21, let-7, and miR-320b) are known to have anti-cancer and/or anti-angiogenic activity." other hsa-mir-141 Colorectal Carcinoma 26179333 Effects of Decitabine on Invasion and Exosomal Expression of miR-200c and miR-141 in Oxaliplatin-Resistant Colorectal Cancer Cells. other hsa-mir-200c Colorectal Carcinoma 26179333 Effects of Decitabine on Invasion and Exosomal Expression of miR-200c and miR-141 in Oxaliplatin-Resistant Colorectal Cancer Cells. other hsa-mir-122 "Carcinoma, Hepatocellular" 26179591 Single-Vehicular Delivery of Antagomir and Small Molecules to Inhibit miR-122 Function in Hepatocellular Carcinoma Cells by using Smart Mesoporous Silica Nanoparticles. other hsa-mir-125b Human Papilloma Virus Infection 26180794 miR-34a and miR-125b Expression in HPV Infection and Cervical Cancer Development. other hsa-mir-34a Human Papilloma Virus Infection 26180794 miR-34a and miR-125b Expression in HPV Infection and Cervical Cancer Development. other hsa-mir-155 Human Immunodeficiency Virus Infection 26181817 Levels of miR-155 and miR-223 but not miR-92 were strongly correlated negatively with EV abundance and size in ART-naive patients. other hsa-mir-223 Human Immunodeficiency Virus Infection 26181817 Levels of miR-155 and miR-223 but not miR-92 were strongly correlated negatively with EV abundance and size in ART-naive patients. other hsa-mir-373 "Adenocarcinoma, Lung" 26182868 MiR-373-3p Promotes Invasion and Metastasis of Lung Adenocarcinoma Cells other hsa-mir-3178 "Carcinoma, Hepatocellular" 26182877 Regulation of tumorigenesis and metastasis of hepatocellular carcinoma tumor endothelial cells by microRNA-3178 and underlying mechanism. other hsa-mir-326 Glioma 26183397 Knockdown of long non-coding RNA HOTAIR inhibits malignant biological behaviors of human glioma cells via modulation of miR-326. other hsa-mir-205 Colorectal Carcinoma 26183718 the integration of multiple omics methods allowed the comprehensive identification of direct and indirect effectors of p53 that provide new insights and leads into the mechanisms of p53-mediated tumor suppression. other hsa-mir-34a Colorectal Carcinoma 26183718 the integration of multiple omics methods allowed the comprehensive identification of direct and indirect effectors of p53 that provide new insights and leads into the mechanisms of p53-mediated tumor suppression. other hsa-mir-486 Colorectal Carcinoma 26183718 the integration of multiple omics methods allowed the comprehensive identification of direct and indirect effectors of p53 that provide new insights and leads into the mechanisms of p53-mediated tumor suppression. other hsa-mir-142 "Carcinoma, Nasopharyngeal" 26183850 MiR-142-3p Suppresses SOCS6 Expression and Promotes Cell Proliferation in Nasopharyngeal Carcinoma. other hsa-mir-21 Colorectal Carcinoma 26184038 IL6 Mediates Immune and Colorectal Cancer Cell Cross-talk via miR-21 and miR-29b. other hsa-mir-29b Colorectal Carcinoma 26184038 IL6 Mediates Immune and Colorectal Cancer Cell Cross-talk via miR-21 and miR-29b. other hsa-mir-33 Mitochondrial Metabolism Disease 26185207 Novel Role of miR-33 in Regulating of Mitochondrial Function. other hsa-mir-206 Gastric Neoplasms 26186594 MicroRNA-206: Effective Inhibition of Gastric Cancer Progression through the c-Met Pathway. other hsa-let-7 Neoplasms [unspecific] 26187994 "Our data reveal an unexpected role of Rho-associated, coiled-coil-containing protein kinase (ROCK1) as a cofactor of HNF4A in enhancing PAIP2 transcription. Rho-associated, coiled-coil-containing protein kinase (ROCK) inhibitors may be useful for the various pathologies associated with the impairment of global miRNA function." other hsa-mir-122 Neoplasms [unspecific] 26187994 "Our data reveal an unexpected role of Rho-associated, coiled-coil-containing protein kinase (ROCK1) as a cofactor of HNF4A in enhancing PAIP2 transcription. Rho-associated, coiled-coil-containing protein kinase (ROCK) inhibitors may be useful for the various pathologies associated with the impairment of global miRNA function." other hsa-mir-124 "Carcinoma, Hepatocellular" 26188282 PABPC1 interacts with AGO2 and is responsible for the microRNA mediated gene silencing in high grade hepatocellular carcinoma. other hsa-mir-183 "Carcinoma, Hepatocellular" 26188282 PABPC1 interacts with AGO2 and is responsible for the microRNA mediated gene silencing in high grade hepatocellular carcinoma. other hsa-mir-26a Pancreatic Neoplasms 26189069 Enhanced phosphorylation of p53 by microRNA-26a leading to growth inhibition of pancreatic cancer. other hsa-mir-21 Neoplasms [unspecific] 26189797 RNA-binding protein HuR sequesters microRNA-21 to prevent translation repression of proinflammatory tumor suppressor gene programmed cell death 4. other hsa-mir-155 Helicobacter pylori Infection 26191144 Inflammatory response of macrophages cultured with Helicobacter pylori strains was regulated by miR-155. other hsa-mir-21 "Squamous Cell Carcinoma, Tongue" 26191145 The role of miR-21 in proliferation and invasion capacity of human tongue squamous cell carcinoma in vitro. other hsa-mir-302a Ovarian Neoplasms 26191180 MiR-302a inhibits the tumorigenicity of ovarian cancer cells by suppression of SDC1. other hsa-mir-188 Rheumatoid Arthritis 26191188 Expression and function of microRNA-188-5p in activated rheumatoid arthritis synovial fibroblasts. other hsa-mir-34 Chronic Obstructive Pulmonary Disease 26191210 These proofs suggest that resveratrol inhibited dysfunction of dendritic cells (DCs) from COPD patients through promoting miR-34. other hsa-mir-21 Neoplasms [unspecific] 26191606 The activated single-stranded DC can project the LAA headgroup into the hCA-II active site and is a robust hCA-II inhibitor (K(i) of 3.12 ¦ÌM). This work may spur research into developing new classes of cancer selective protein inhibitors. other hsa-mir-155 Pancreatic Neoplasms 26195069 Pancreatic cancer-secreted miR-155 implicates in the conversion from normal fibroblasts to cancer-associated fibroblasts. other hsa-mir-122 Growth Disorders 26198739 "Why is microRNA action tissue specific. A putative defense mechanism against growth disorders, tumor development or progression mediated by circulating microRNA" other hsa-mir-15 Growth Disorders 26198739 "Why is microRNA action tissue specific. A putative defense mechanism against growth disorders, tumor development or progression mediated by circulating microRNA" other hsa-mir-16 Growth Disorders 26198739 "Why is microRNA action tissue specific. A putative defense mechanism against growth disorders, tumor development or progression mediated by circulating microRNA" other hsa-mir-21 Growth Disorders 26198739 "Why is microRNA action tissue specific. A putative defense mechanism against growth disorders, tumor development or progression mediated by circulating microRNA" other hsa-mir-503 Growth Disorders 26198739 "Why is microRNA action tissue specific. A putative defense mechanism against growth disorders, tumor development or progression mediated by circulating microRNA" other hsa-mir-221 "Carcinoma, Renal Cell" 26201448 Gain of function experiments showed that miR-221 and miR-222 decreased angiogenesis and cellular proliferation in human umbilical vein endothelial cells (HUVEC) while increasing cellular proliferation in ACHN cells. miRNAs represent potential predictive markers for sunitinib response. other hsa-mir-222 "Carcinoma, Renal Cell" 26201448 Gain of function experiments showed that miR-221 and miR-222 decreased angiogenesis and cellular proliferation in human umbilical vein endothelial cells (HUVEC) while increasing cellular proliferation in ACHN cells. miRNAs represent potential predictive markers for sunitinib response. other hsa-mir-573 "Carcinoma, Hepatocellular" 26201458 The miR-573/apoM/Bcl2A1-dependent signal transduction pathway is essential for hepatocyte apoptosis and hepatocarcinogenesis. other hsa-mir-223 Pulmonary Hypertension 26201953 MicroRNAs and PARP: co-conspirators with ROS in pulmonary hypertension. Focus on miR-223 reverses experimental pulmonary arterial hypertension. other hsa-mir-497 Osteosarcoma 26202364 "Taken together, our results suggest that miR-497 modulates the sensitivity to cisplatin at least in part through PI3K/Akt pathway in osteosarcoma cells." other hsa-let-7a Digeorge Syndrome 26202964 "Collectively, our data suggest a novel mechanism that SUMOylation of DGCR8 controls direct functions of pri-miRNAs in gene silencing." other hsa-mir-125b Aortic Insufficiency 26203686 MicroRNA-125b and chemokine CCL4 expression are associated with calcific aortic valve disease. other hsa-mir-221 Viral Myocarditis 26206211 "The miR-221/-222 cluster orchestrates the antiviral and inflammatory immune response to viral infection of the heart. Its inhibition increases viral load, inflammation, and overall cardiac injury upon VM." other hsa-mir-222 Viral Myocarditis 26206211 "The miR-221/-222 cluster orchestrates the antiviral and inflammatory immune response to viral infection of the heart. Its inhibition increases viral load, inflammation, and overall cardiac injury upon VM." other hsa-mir-9 "Carcinoma, Hepatocellular" 26206264 this study revealed the involvement of the miR-9/PPARA/CDH1 signaling pathway in HCC oncogenesis. other hsa-mir-100 Inflammation 26209130 Such delicately counterbalanced systems are a hallmark of immune plasticity and we propose that miR-100 editing is a novel mechanism toward this end. other hsa-let-7a "Carcinoma, Cervical" 26209160 The effects of lanthanum chloride on proliferation and apoptosis of cervical cancer cells: involvement of let-7a and miR-34a microRNAs. other hsa-mir-34a "Carcinoma, Cervical" 26209160 The effects of lanthanum chloride on proliferation and apoptosis of cervical cancer cells: involvement of let-7a and miR-34a microRNAs. other hsa-mir-3651 "Squamous Cell Carcinoma, Esophageal" 26210449 Clinical potential of miR-3651 as a novel prognostic biomarker for esophageal squamous cell cancer. other hsa-mir-203a "Carcinoma, Hepatocellular" 26210453 Downregulation of miRNA-30c and miR-204a is associated with hepatitis C virus core protein-induced epithelial-mesenchymal transition in normal hepatocytes and hepatocellular carcinoma cells. other hsa-mir-30c "Carcinoma, Hepatocellular" 26210453 Downregulation of miRNA-30c and miR-203a is associated with hepatitis C virus core protein-induced epithelial-mesenchymal transition in normal hepatocytes and hepatocellular carcinoma cells. other hsa-mir-146a Gastrointestinal Neoplasms 26211779 miR-146a cancer susceptibility gene polymorphism is closely associated with gastrointestinal cancers. other hsa-mir-200 "Carcinoma, Ovarian" 26213923 The miR-200 Family: Versatile Players in Epithelial Ovarian Cancer. other hsa-mir-17 Colorectal Carcinoma 26215320 Calycosin induces apoptosis by the regulation of ER¦Â/miR-17 signaling pathway in human colorectal cancer cells. other hsa-mir-431 Muscle Diseases [unspecific] 26215566 our results suggest that the age-associated miR-431 plays a key role in maintaining the myogenic ability of skeletal muscle with age. other hsa-mir-137 Breast Neoplasms 26215676 A contrasting function for miR-137 in embryonic mammogenesis and adult breast carcinogenesis. other hsa-mir-150 "Carcinoma, Hepatocellular" 26215970 microRNA-150: a promising novel biomarker for hepatitis B virus-related hepatocellular carcinoma. other hsa-mir-153 Lung Fibrosis 26216407 "These data suggest that miR-153 disturbs TGF-¦Â1 signal transduction and its effects on fibroblast activation, acting as an anti-fibrotic element in the development of pulmonary fibrosis." other hsa-mir-375 Hypogonadism 26219823 "we identified miR-375 as an androgen regulated microRNA, which could play an important role for understanding the mechanism of the increase in visceral fat mass and the associated insulin resistance caused by testosterone deficiency." other hsa-mir-21 Neoplasms [unspecific] 26220158 "preliminary mechanism of action studies propose a different mode of action compared to previously reported miR-21 inhibitors, thus affording a new chemical probe for future studies." other hsa-mir-1 Atrial Fibrillation 26221584 The results suggest that immediate-early miRNA remodeling coupled with deregulation of TF expression underlies the onset of AF. other hsa-mir-10a Atrial Fibrillation 26221584 The results suggest that immediate-early miRNA remodeling coupled with deregulation of TF expression underlies the onset of AF. other hsa-mir-10b Atrial Fibrillation 26221584 The results suggest that immediate-early miRNA remodeling coupled with deregulation of TF expression underlies the onset of AF. other hsa-mir-21 Atrial Fibrillation 26221584 The results suggest that immediate-early miRNA remodeling coupled with deregulation of TF expression underlies the onset of AF. other hsa-mir-221 Atherosclerosis 26221589 Human miR-221/222 in Physiological and Atherosclerotic Vascular Remodeling. other hsa-mir-222 Atherosclerosis 26221589 Human miR-221/222 in Physiological and Atherosclerotic Vascular Remodeling. other hsa-mir-330 "Adenocarcinoma, Esophageal" 26221725 MicroRNA-330-5p as a Putative Modulator of Neoadjuvant Chemoradiotherapy Sensitivity in Oesophageal Adenocarcinoma. other hsa-mir-106a "Carcinoma, Colon" 26224446 Long non-coding RNA Fer-1-like protein 4 suppresses oncogenesis and exhibits prognostic value by associating with miR-106a-5p in colon cancer. other hsa-mir-124 "Squamous Cell Carcinoma, Head and Neck" 26227488 miR-124 Regulates the Epithelial-Restricted with Serine Box/Epidermal Growth Factor Receptor Signaling Axis in Head and Neck Squamous Cell Carcinoma. other hsa-mir-34a Prostate Neoplasms 26231042 Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. other hsa-mir-17 "Carcinoma, Hepatocellular" 26231474 MiR-17-95 cluster promotes hepatocarcinogenesis. other hsa-mir-18 "Carcinoma, Hepatocellular" 26231474 MiR-17-95 cluster promotes hepatocarcinogenesis. other hsa-mir-19a "Carcinoma, Hepatocellular" 26231474 MiR-17-95 cluster promotes hepatocarcinogenesis. other hsa-mir-19b-1 "Carcinoma, Hepatocellular" 26231474 MiR-17-95 cluster promotes hepatocarcinogenesis. other hsa-mir-20a "Carcinoma, Hepatocellular" 26231474 MiR-17-95 cluster promotes hepatocarcinogenesis. other hsa-mir-92-1 "Carcinoma, Hepatocellular" 26231474 MiR-17-95 cluster promotes hepatocarcinogenesis. other hsa-mir-4295 Thyroid Neoplasms 26231799 miR-4295 promotes cell proliferation and invasion in anaplastic thyroid carcinoma via CDKN1A. other hsa-mir-17 "Carcinoma, Hepatocellular" 26232302 MiR-17-94 cluster promotes hepatocarcinogenesis. other hsa-mir-18 "Carcinoma, Hepatocellular" 26232302 MiR-17-94 cluster promotes hepatocarcinogenesis. other hsa-mir-19a "Carcinoma, Hepatocellular" 26232302 MiR-17-94 cluster promotes hepatocarcinogenesis. other hsa-mir-19b-1 "Carcinoma, Hepatocellular" 26232302 MiR-17-94 cluster promotes hepatocarcinogenesis. other hsa-mir-20a "Carcinoma, Hepatocellular" 26232302 MiR-17-94 cluster promotes hepatocarcinogenesis. other hsa-mir-92-1 "Carcinoma, Hepatocellular" 26232302 MiR-17-94 cluster promotes hepatocarcinogenesis. other hsa-mir-17 "Carcinoma, Hepatocellular" 26233130 MiR-17-93 cluster promotes hepatocarcinogenesis. other hsa-mir-18 "Carcinoma, Hepatocellular" 26233130 MiR-17-93 cluster promotes hepatocarcinogenesis. other hsa-mir-19a "Carcinoma, Hepatocellular" 26233130 MiR-17-93 cluster promotes hepatocarcinogenesis. other hsa-mir-19b-1 "Carcinoma, Hepatocellular" 26233130 MiR-17-93 cluster promotes hepatocarcinogenesis. other hsa-mir-20a "Carcinoma, Hepatocellular" 26233130 MiR-17-93 cluster promotes hepatocarcinogenesis. other hsa-mir-92-1 "Carcinoma, Hepatocellular" 26233130 MiR-17-93 cluster promotes hepatocarcinogenesis. other hsa-mir-106b Colorectal Carcinoma 26238857 MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer. other hsa-mir-19a "Carcinoma, Gastric" 26239140 MicroRNA-19a mediates gastric carcinoma cell proliferation through the activation of nuclear factor-¦ÊB. other hsa-mir-146a Glioblastoma 26239619 Induction of microRNA-146a is involved in curcumin-mediated enhancement of temozolomide cytotoxicity against human glioblastoma. other hsa-mir-122 Osteoarthritis 26239639 An insertion/deletion polymorphism at the microRNA-122 binding site in the interleukin-1¦Á 3'-untranslated region is associated with a risk for osteoarthritis. other hsa-let-7f Asthma 26242299 "17¦Â-E2+P4 increased IL-17A production from TH17 cells, providing a potential mechanism for the increased prevalence of severe asthma in women compared with men." other hsa-mir-21 Meningioma 26242334 "Increased miR-21 and nestin mRNA levels were found in anaplastic meningiomas, in which recurrence is common, and the role of miR-21 and Nestin in meningiomas therefore warrants further investigation." other hsa-mir-335 Osteoarthritis 26243143 Signature of microRNA expression during osteogenic differentiation of bone marrow MSCs reveals a putative role of miR-335-5p in osteoarthritis. other hsa-mir-126 Thyroid Neoplasms 26244545 "To our knowledge, this is the first study to demonstrate that miR-126-3p has a tumor-suppressive function in thyroid cancer cells, and is associated with aggressive disease phenotype." other hsa-mir-367 Medulloblastoma 26250335 miR-367 promotes proliferation and stem-like traits in medulloblastoma cells. other hsa-mir-29a "Leukemia, Lymphoblastic, Acute" 26251039 Potential roles of microRNA-29a in the molecular pathophysiology of T-cell acute lymphoblastic leukemia. other hsa-mir-199a Lymphoma 26251897 miR-199a and miR-497 Are Associated with Better Overall Survival due to Increased Chemosensitivity in Diffuse Large B-Cell Lymphoma Patients. other hsa-mir-497 Lymphoma 26251897 miR-199a and miR-497 Are Associated with Better Overall Survival due to Increased Chemosensitivity in Diffuse Large B-Cell Lymphoma Patients. other hsa-mir-144 Breast Neoplasms 26252024 "MicroRNA-144 affects radiotherapy sensitivity by promoting proliferation,migration and invasion of breast cancer cells." other hsa-mir-374a "Carcinoma, Esophageal" 26252180 MicroRNA-374a promotes esophageal cancer cell proliferation via Axin2 suppression. other hsa-mir-143 "Squamous Cell Carcinoma, Cerevial" 26252302 A Functional Polymorphism in the Promoter of MiR-143/145 Is Associated With the Risk of Cervical Squamous Cell Carcinoma in Chinese Women: A Case-Control Study. other hsa-mir-145 "Squamous Cell Carcinoma, Cerevial" 26252302 A Functional Polymorphism in the Promoter of MiR-143/145 Is Associated With the Risk of Cervical Squamous Cell Carcinoma in Chinese Women: A Case-Control Study. other hsa-mir-24 Respiratory Syncytial Virus Pneumonia 26253191 Human respiratory syncytial virus non-structural protein NS1 modifies miR-24 expression via transforming growth factor-¦Â. other hsa-mir-148a "Squamous Cell Carcinoma, Skin or Unspecific" 26253263 Role of miR-148a in cutaneous squamous cell carcinoma by repression of MAPK pathway. other hsa-mir-30a Glioma 26255203 MiR-30a-5p is induced by Wnt/¦Â-catenin pathway and promotes glioma cell invasion by repressing NCAM. other hsa-mir-100 "Carcinoma, Rectal" 26255374 "The proposed methodology effectively made use of literature data and was able to show novel,significant miRNA-transcription associations in CRC." other hsa-mir-630 "Carcinoma, Rectal" 26255374 "The proposed methodology effectively made use of literature data and was able to show novel,significant miRNA-transcription associations in CRC." other hsa-mir-99a "Carcinoma, Rectal" 26255374 "The proposed methodology effectively made use of literature data and was able to show novel,significant miRNA-transcription associations in CRC." other hsa-mir-17 Neoplasms [unspecific] 26255770 developmentally regulated pro-miRNA processing is a key step controlling miRNA expression and explains the posttranscriptional control of miR-17-92 expression in development. other hsa-mir-451 Neoplasms [unspecific] 26257001 "Both, energy-conserving metabolic shift and resource-seeking behavioral change require brain tumor cell to shut down miR-451, while forced expression of miR-451 during stress leads to cytotoxicity [3]. The AMPK-dependent inactivation of the OCT1 transcriptional activator of miR-451 helps brain tumor cells to escape from metabolically stressful events/locations. MiR-451 thus provides an example of a molecule that is not deregulated in brain tumor cells, but is instead finely regulated by promoting or suppressing brain tumor cell phenotypes based on microenvironmental contexts." other hsa-let-7i "Squamous Cell Carcinoma, Head and Neck" 26257063 IB suppresses EMT and stemness of HNSCC cells through inhibition of Twist1-mediated let-7i downregulation and Rac1 activation and the EMT signalling. other hsa-mir-128 Neuroblastoma 26258008 Such miRNAs regulate genes involved in cellular processes other hsa-mir-130a Neuroblastoma 26258008 Such miRNAs regulate genes involved in cellular processes other hsa-mir-181a Neuroblastoma 26258008 Such miRNAs regulate genes involved in cellular processes other hsa-mir-18a Neuroblastoma 26258008 Such miRNAs regulate genes involved in cellular processes other hsa-mir-21 Neuroblastoma 26258008 Such miRNAs regulate genes involved in cellular processes other hsa-mir-218 Neuroblastoma 26258008 Such miRNAs regulate genes involved in cellular processes other hsa-mir-380 Neuroblastoma 26258008 Such miRNAs regulate genes involved in cellular processes other hsa-mir-424 Neuroblastoma 26258008 Such miRNAs regulate genes involved in cellular processes other hsa-mir-451 Neuroblastoma 26258008 Such miRNAs regulate genes involved in cellular processes other hsa-mir-558 Neuroblastoma 26258008 Such miRNAs regulate genes involved in cellular processes other hsa-mir-7 Neuroblastoma 26258008 Such miRNAs regulate genes involved in cellular processes other hsa-mir-373 Breast Neoplasms 26258411 Epigenetic silencing of ITGA2 by MiR-373 promotes cell migration in breast cancer. other hsa-mir-21 Ischemia-Reperfusion Injury 26259139 Isoflurane protects mouse hearts from ischemia-reperfusion injury by a microRNA-21-dependent mechanism. other hsa-mir-15a Neoplasms [unspecific] 26260813 miRNA-15a/16: as tumor suppressors and more. other hsa-mir-16 Neoplasms [unspecific] 26260813 miRNA-15a/16: as tumor suppressors and more. other hsa-mir-127 Glioma 26261488 Knockdown of microRNA-127 reverses adriamycin resistance via cell cycle arrest and apoptosis sensitization in adriamycin-resistant human glioma cells. other hsa-mir-1908 Glioblastoma 26265437 miRNA-1908 functions as an oncogene in glioblastoma by repressing the PTEN pathway. MiR-1908 is a potential new molecular marker for predicting the risk of recurrence and prognosis of glioblastoma. other hsa-mir-21 Gastric Neoplasms 26265521 MicroRNA-21: Mechanisms of Oncogenesis and its Application in Diagnosis and Prognosis of Gastric Cancer. other hsa-mir-124 Glioma 26269187 Our findings indicate a clear benefit in harnessing the wild-type virus replicative potency in development of next-generation oncolytic alphaviruses. other hsa-mir-21 Breast Neoplasms 26270351 Breast Cancer/Stromal Cells Coculture on Polyelectrolyte Films Emulates Tumor Stages and miRNA Profiles of Clinical Samples. other hsa-mir-21 Neoplasms [unspecific] 26271820 MicroRNA-Responsive Cancer Cell Imaging and Therapy with Functionalized Gold Nanoprobe. other hsa-mir-429 Glioma 26272601 Our results indicated that BMK1 modulation by miR-429 has an important function in glioma invasion both in vitro and in vivo. other hsa-let-7 Muscular Dystrophy 26272747 Our study therefore introduces additional biological players in the regulation of skeletal muscle structure and myogenesis that may contribute to unexplained disorders of MD. other hsa-let-7e Muscular Dystrophy 26272747 Our study therefore introduces additional biological players in the regulation of skeletal muscle structure and myogenesis that may contribute to unexplained disorders of MD. other hsa-mir-98 Muscular Dystrophy 26272747 Our study therefore introduces additional biological players in the regulation of skeletal muscle structure and myogenesis that may contribute to unexplained disorders of MD. other hsa-mir-150 Autoimmune Diseases [unspecific] 26275076 dysregulated expression of miR-150 in immune cells might result in autoimmune diseases. other hsa-mir-1 Breast Neoplasms 26275461 Our findings emphasized the potential role of miR-1 as tumor suppressive miRNA in breast cancer. other hsa-mir-491 "Carcinoma, Esophageal" 26279431 miR-491 may play a critical role in EC. other hsa-mir-132 Granulosa Cell Tumor 26282993 Our findings suggest that miR-132 is involved in the cAMP signaling pathway and promotes estradiol synthesis via the translational repression of Nurr1 in ovarian GCs. other hsa-mir-200a Breast Neoplasms 26283635 Identification of miR-200a as a novel suppressor of connexin 43 in breast cancer cells. other hsa-mir-92a Diabetes Mellitus 26283734 miR-92a Corrects CD34+ Cell Dysfunction in Diabetes by Modulating Core Circadian Genes Involved in Progenitor Differentiation. other hsa-let-7 Malignant Neoplasms [unspecific] 26285684 "and messenger RNAs and microRNAs miR-21, miR-27a, let-7, miR-451, among others." other hsa-mir-21 Malignant Neoplasms [unspecific] 26285684 "and messenger RNAs and microRNAs miR-21, miR-27a, let-7, miR-451, among others." other hsa-mir-27a Malignant Neoplasms [unspecific] 26285684 "and messenger RNAs and microRNAs miR-21, miR-27a, let-7, miR-451, among others." other hsa-mir-451 Malignant Neoplasms [unspecific] 26285684 "and messenger RNAs and microRNAs miR-21, miR-27a, let-7, miR-451, among others." other hsa-mir-335 "Leukemia, Myeloid, Acute" 26287405 Our finding suggests that bone marrow miR-335 level may be used as a marker to predict the chemotherapy response and prognosis in adult AML patients. other hsa-mir-200 Cystic Fibrosis 26292219 Transcription Factor Hepatocyte Nuclear Factor-1¦Â (HNF-1¦Â) Regulates MicroRNA-200 Expression through a Long Noncoding RNA. other hsa-mir-21 Leukemia 26294715 "In this issue of Blood, Junker et al delineate a novel signaling axis involving miR-21 and the tumor suppressor Pdcd4 that is essential for Notch-mediated induction of T-cell acute lymphoblastic leukemia (T-ALL)." other hsa-mir-24 Ovarian Neoplasms 26296081 Enrichment Analysis Identifies Functional MicroRNA-Disease Associations in Humans. other hsa-mir-454 Uveal Melanoma 26296312 Our data revealed that ectopic expression of PTEN restored the effects of miR-454 on cell proliferation and invasion in uveal melanoma cells. These findings support an oncogene role of miR-454 in development of uveal melanoma. other hsa-mir-30 Influenza 26296570 RNA interference of influenza A virus replication by microRNA-adapted lentiviral loop short hairpin RNA. other hsa-mir-107 "Carcinoma, Hepatocellular" 26296971 miRNA-7/21/108 contribute to HBx-induced hepatocellular carcinoma progression through suppression of maspin. other hsa-mir-21 "Carcinoma, Hepatocellular" 26296971 miRNA-7/21/109 contribute to HBx-induced hepatocellular carcinoma progression through suppression of maspin. other hsa-mir-7 "Carcinoma, Hepatocellular" 26296971 miRNA-7/21/107 contribute to HBx-induced hepatocellular carcinoma progression through suppression of maspin. other hsa-mir-137 "Diabetes Mellitus, Gestational" 26302821 Our data identified a miRNA signature involvement in GDM which may contribute to macrosomia through enhancing EGFR signaling. other hsa-mir-27a "Diabetes Mellitus, Gestational" 26302821 Our data identified a miRNA signature involvement in GDM which may contribute to macrosomia through enhancing EGFR signaling. other hsa-mir-30d "Diabetes Mellitus, Gestational" 26302821 Our data identified a miRNA signature involvement in GDM which may contribute to macrosomia through enhancing EGFR signaling. other hsa-mir-33a "Diabetes Mellitus, Gestational" 26302821 Our data identified a miRNA signature involvement in GDM which may contribute to macrosomia through enhancing EGFR signaling. other hsa-mir-362 "Diabetes Mellitus, Gestational" 26302821 Our data identified a miRNA signature involvement in GDM which may contribute to macrosomia through enhancing EGFR signaling. other hsa-mir-502 "Diabetes Mellitus, Gestational" 26302821 Our data identified a miRNA signature involvement in GDM which may contribute to macrosomia through enhancing EGFR signaling. other hsa-mir-508 "Diabetes Mellitus, Gestational" 26302821 Our data identified a miRNA signature involvement in GDM which may contribute to macrosomia through enhancing EGFR signaling. other hsa-mir-9 "Diabetes Mellitus, Gestational" 26302821 Our data identified a miRNA signature involvement in GDM which may contribute to macrosomia through enhancing EGFR signaling. other hsa-mir-92a "Diabetes Mellitus, Gestational" 26302821 Our data identified a miRNA signature involvement in GDM which may contribute to macrosomia through enhancing EGFR signaling. other hsa-mir-19a Colorectal Carcinoma 26302825 "Collectively, miR-19a played an important role in mediating EMT and metastatic behavior in CRC. It may serve as a potential marker of lymph node metastasis." other hsa-mir-22 Aortic Stenosis 26304936 "Despite holding great promise, circulating miRNA profiling requires further refinement before translation into clinical use as a biomarker in aortic stenosis." other hsa-mir-24 Aortic Stenosis 26304936 "Despite holding great promise, circulating miRNA profiling requires further refinement before translation into clinical use as a biomarker in aortic stenosis." other hsa-mir-382 Aortic Stenosis 26304936 "Despite holding great promise, circulating miRNA profiling requires further refinement before translation into clinical use as a biomarker in aortic stenosis." other hsa-mir-451a Aortic Stenosis 26304936 "Despite holding great promise, circulating miRNA profiling requires further refinement before translation into clinical use as a biomarker in aortic stenosis." other hsa-mir-223 Multiple Sclerosis 26305248 Variants of MicroRNA Genes: Gender-Specific Associations with Multiple Sclerosis Risk and Severity. other hsa-mir-499a Multiple Sclerosis 26305248 Variants of MicroRNA Genes: Gender-Specific Associations with Multiple Sclerosis Risk and Severity. other hsa-mir-23a "Carcinoma, Hepatocellular" 26305257 up-regulating the expression of miR-23a may activate the positive regulatory network of p53 and miR-23a involved in the mechanism underlying the anti-tumor effect of berberine in hepatocellular carcinoma (HCC). other hsa-mir-663b "Leukemia, Lymphocytic, Chronic, B-Cell" 26305332 Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells. other hsa-mir-122 Hepatitis C Virus Infection 26305877 Supporting Role for GTPase Rab27a in Hepatitis C Virus RNA Replication through a Novel miR-122-Mediated Effect. other hsa-mir-410 Diabetes Mellitus 26307561 miR-410 enhanced hESC-derived pancreatic endoderm transplant to alleviate gestational diabetes mellitus. other hsa-mir-26b Colorectal Carcinoma 26308439 Clinical Value of miR-26b Discriminating Ulcerative Colitis-associated Colorectal Cancer in the Subgroup of Patients with Metastatic Disease. other hsa-mir-29 Atherosclerosis 26309238 Transcriptional and posttranscriptional mechanisms contribute to the dysregulation of elastogenesis in Schimke immuno-osseous dysplasia. other hsa-mir-30b Gastric Neoplasms 26309359 "Our findings describe a link between miR-30b and EIF5A2, which plays an important role in mediating epithelial-mesenchymal transition." other hsa-mir-21 Coronary Artery Disease 26310808 Local anti-miR delivery: the latest in the arsenal of drug-eluting stents other hsa-mir-200c Breast Neoplasms 26310899 "selected miRNAs, such as miR-200c and miR-34a, may influence response to chemotherapy in several tumor types" other hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 26311306 Validation for histology-driven diagnosis in non-small cell lung cancer using hsa-miR-205 and hsa-miR-21 expression by two different normalization strategies. other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 26311306 Validation for histology-driven diagnosis in non-small cell lung cancer using hsa-miR-205 and hsa-miR-21 expression by two different normalization strategies. other hsa-mir-10b Gastric Neoplasms 26311318 "miR-10b promotes migration and invasion through Hoxd10 in human gastric cancer cell lines and may play an important role in tumorigenesis,progression, and prognosis." other hsa-mir-375 Diabetes Mellitus 26311337 "This review analyzes the role of miRNAs in obesity and insulin resistance, focusing on the miR-17/92, miR-143-145, miR-130, let-7, miR-221/222, miR-200, miR-223, miR-29 and miR-375 families, as well as miRNA changes by relevant tissue" other hsa-mir-126 Atrial Fibrillation 26313139 Biological significance of miR-126 expression in atrial fibrillation and heart failure. other hsa-mir-126 Heart Failure 26313139 Biological significance of miR-126 expression in atrial fibrillation and heart failure. other hsa-mir-15b Pancreatic Neoplasms 26314585 Pancreatic tumours are usually very aggressive cancer with a poor prognosis. other hsa-mir-186 Pancreatic Neoplasms 26314585 Pancreatic tumours are usually very aggressive cancer with a poor prognosis. other hsa-mir-190 Pancreatic Neoplasms 26314585 Pancreatic tumours are usually very aggressive cancer with a poor prognosis. other hsa-mir-200b Pancreatic Neoplasms 26314585 Pancreatic tumours are usually very aggressive cancer with a poor prognosis. other hsa-mir-221 Pancreatic Neoplasms 26314585 Pancreatic tumours are usually very aggressive cancer with a poor prognosis. other hsa-mir-222 Pancreatic Neoplasms 26314585 Pancreatic tumours are usually very aggressive cancer with a poor prognosis. other hsa-mir-95 Pancreatic Neoplasms 26314585 Pancreatic tumours are usually very aggressive cancer with a poor prognosis. other hsa-mir-15a "Carcinoma, Lung, Non-Small-Cell" 26314859 We found that induced expression of hsa-miR-15a-3p via mimic transfection sensitised cisplatin-resistant cells to apoptosis and autophagy. other hsa-mir-338 "Carcinoma, Hepatocellular" 26315112 HBV preS2 promotes the expression of TAZ via miRNA-338-3p to enhance the tumorigenesis of hepatocellular carcinoma. other hsa-mir-424 "Carcinoma, Hepatocellular" 26315541 MicroRNA-424 inhibits Akt3/E2F3 axis and tumor growth in hepatocellular carcinoma. other hsa-mir-138 Colorectal Carcinoma 26316117 Downregulation of miR-138 as a Contributing Mechanism to Lcn-2 Overexpression in Colorectal Cancer with Liver Metastasis. other hsa-mir-155 Neoplasms [unspecific] 26317550 Our results demonstrate that miR-155 inhibits the ability of cancer cells to extravasate and/or colonize at distant organs and brings additional insight into the complexity of miR-155 regulation in metastatic seeding. other hsa-mir-31 Diabetes Mellitus 26318001 "Comparative Genomic, MicroRNA, and Tissue Analyses Reveal Subtle Differences between Non-Diabetic and Diabetic Foot Skin." other hsa-mir-140 "Carcinoma, Embryonal" 26318829 Role of miR-140 in embryonic bone development and cancer. other hsa-mir-21 Malignant Neoplasms [unspecific] 26320972 Toehold-mediated nonenzymatic amplification circuit on graphene oxide fluorescence switching platform for sensitive and homogeneous microRNA detection. other hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 26322518 These results suggest that miR-155 expression is not significantly related to non-small cell lung cancer patients except in patients from Asian and America. other hsa-mir-145 Breast Neoplasms 26324407 Physicochemical and biological characterization of chitosan-microRNA nanocomplexes for gene delivery to MCF-7 breast cancer cells. other hsa-mir-15b "Leukemia, Lymphocytic, Chronic, B-Cell" 26324892 "These results are the first, to our knowledge, to suggest an important role of miR-15b/16-2 loss in the pathogenesis of B-cell chronic lymphocytic leukemia." other hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 26324892 "These results are the first, to our knowledge, to suggest an important role of miR-15b/16-2 loss in the pathogenesis of B-cell chronic lymphocytic leukemia." other hsa-mir-142 Heart Failure 26327117 miR-142-5p has been proposed to control adaptive growth in cardiomyocytes postnatally and its increase is associated with extensive apoptosis and cardiac dysfunction in a murine heart failure model. other hsa-mir-122 Hepatitis C Virus Infection 26330540 These results show that hnRNP K is a cellular protein that binds and affects the accumulation of miR-122. Its ability to also bind HCV RNA near the miR-122 binding site suggests a role for miR-122 recognition of HCV RNA. other hsa-mir-200c Neoplasms [unspecific] 26334100 "In summary, TKS5 and MYLK represent two mediators of invasive behavior of cancer cells that are regulated by the ZEB1/miR-200 feedback loop." other hsa-mir-200b "Squamous Cell Carcinoma, Esophageal" 26334393 These data highlight that suppression of the Kindlin-2-integrin ¦Â1-AKT regulatory axis is an alternative mechanism underlying the tumor suppressor function of miR-200b in ESCC. other hsa-mir-155 Leukemia 26337206 "Altogether, these data implicate QKI in the pathophysiology of inflammation and oncogenesis where miR-155 is involved." other hsa-mir-222 Melanoma 26338962 miR-222 could function as a biomarker for the prediction of response to ipilimumab other hsa-mir-205 Thyroid Neoplasms 26342107 The angiogenic and tumour-suppressive roles of miRNA-205 were demonstrated for the first time in thyroid cancer. The current experiments provided specific information on the functional consequences of VEGF manipulation via miRNA on cancer. other hsa-mir-21 "Leukemia, Myeloid, Acute" 26344648 "GRh2 may be an effective treatment for pediatric leukemia, and GRh2 may induce apoptosis of leukemia cells through miR-21-modulated suppression of Bcl-2." other hsa-mir-30a Nephrotic Syndrome 26345917 "Analysis of the expression of HMGB-1, CXCL16, miRNA-30a, and TGF-¦Â1 in primary nephritic syndrome patients and its significance." other hsa-mir-223 Sepsis 26348153 Exosomal miR-223 Contributes to Mesenchymal Stem Cell-Elicited Cardioprotection in Polymicrobial Sepsis. other hsa-let-7b Vascular Disease [unspecific] 26348824 only let-7b and miR-133a were markedly upregulated. other hsa-mir-21 Breast Neoplasms 26349663 "These results indicate that miRNAs show promising associations with prognosis in breast cancer. Moreover, specific miRNAs such as miR-21 and miR-210 can predict poor survival rates in breast cancer patients." other hsa-mir-210 Breast Neoplasms 26349663 "These results indicate that miRNAs show promising associations with prognosis in breast cancer. Moreover, specific miRNAs such as miR-21 and miR-210 can predict poor survival rates in breast cancer patients." other hsa-mir-126 Malignant Neoplasms [unspecific] 26351404 Our results indicated that miR-126 could act as a significant biomarker in the prognosis of various cancers. other hsa-mir-137 "Carcinoma, Hepatocellular" 26352279 Inhibition of cell proliferation and metastasis of human hepatocellular carcinoma by miR-137 is regulated by CDC42. other hsa-mir-126 Aplastic Anemia 26354756 Identification of novel microRNA signatures linked to acquired aplastic anemia. other hsa-mir-145 Aplastic Anemia 26354756 Identification of novel microRNA signatures linked to acquired aplastic anemia. other hsa-mir-199a Aplastic Anemia 26354756 Identification of novel microRNA signatures linked to acquired aplastic anemia. other hsa-mir-223 Aplastic Anemia 26354756 Identification of novel microRNA signatures linked to acquired aplastic anemia. other hsa-mir-143 Bladder Neoplasms 26356996 Cisplatin and Paclitaxel Alter the Expression Pattern of miR-143/145 and miR-183/96/182 Clusters in T24 Bladder Cancer Cells. other hsa-mir-145 Bladder Neoplasms 26356996 Cisplatin and Paclitaxel Alter the Expression Pattern of miR-143/145 and miR-183/96/182 Clusters in T24 Bladder Cancer Cells. other hsa-mir-182 Bladder Neoplasms 26356996 Cisplatin and Paclitaxel Alter the Expression Pattern of miR-143/145 and miR-183/96/182 Clusters in T24 Bladder Cancer Cells. other hsa-mir-183 Bladder Neoplasms 26356996 Cisplatin and Paclitaxel Alter the Expression Pattern of miR-143/145 and miR-183/96/182 Clusters in T24 Bladder Cancer Cells. other hsa-mir-96 Bladder Neoplasms 26356996 Cisplatin and Paclitaxel Alter the Expression Pattern of miR-143/145 and miR-183/96/182 Clusters in T24 Bladder Cancer Cells. other hsa-mir-34a Breast Neoplasms 26359358 These data provide evidence for the leptin-antagonist potential of HNK and reveal the involvement of LKB1 and miR-34a. other hsa-mir-101 Breast Neoplasms 26360780 MiRNA-101 inhibits breast cancer growth and metastasis by targeting CX chemokine receptor 7. other hsa-mir-122 Neoplasms [unspecific] 26360933 "In conclusion, administration of TSA in hepatogenic differentiation of hAT-MSCs resulted in higher expression levels of miR-122,facilitation of differentiation, and subsequently attenuation of AFP levels." other hsa-mir-22 Panic Disorder 26361067 This is the first report to show possible associations of miR-22 and miR-491 with genetic susceptibility to PD in a Korean population. other hsa-mir-491 Panic Disorder 26361067 This is the first report to show possible associations of miR-22 and miR-491 with genetic susceptibility to PD in a Korean population. other hsa-mir-302 Kidney Neoplasms 26363379 Evolutionary conservation and function of the human embryonic stem cell specific miR-302/367 cluster. other hsa-mir-367 Kidney Neoplasms 26363379 Evolutionary conservation and function of the human embryonic stem cell specific miR-302/367 cluster. other hsa-mir-221 Gastric Neoplasms 26364844 The miR-221/miR-222-RECK axis might be an important path modulating H. pylori infection-related gastric cancer development. other hsa-mir-222 Gastric Neoplasms 26364844 The miR-221/miR-222-RECK axis might be an important path modulating H. pylori infection-related gastric cancer development. other hsa-mir-486 Lung Fibrosis 26370615 The Anti-fibrotic Effects and Mechanisms of MicroRNA-486-5p in Pulmonary Fibrosis. other hsa-mir-16 Bladder Neoplasms 26373319 "Together, our results revealed that urothelial carcinoma-associated 1 regulated the expression of GLS2 through interfering with miR-16, and repressed ROS formation in bladder cancer cells." other hsa-mir-148b "Carcinoma, Lung, Non-Small-Cell" 26377406 Our findings demonstrated that miR-148b may play a role as independent prognostic factor for patients with NSCLC. other hsa-mir-140 Breast Neoplasms 26378051 the existence of common pathways driving breast carcinogenesis in both BRCA1 and BRCA2 germ-line mutation carriers. other hsa-mir-320c Breast Neoplasms 26378051 the existence of common pathways driving breast carcinogenesis in both BRCA1 and BRCA2 germ-line mutation carriers. other hsa-mir-335 Breast Neoplasms 26378051 the existence of common pathways driving breast carcinogenesis in both BRCA1 and BRCA2 germ-line mutation carriers. other hsa-mir-486 Breast Neoplasms 26378051 the existence of common pathways driving breast carcinogenesis in both BRCA1 and BRCA2 germ-line mutation carriers. other hsa-mir-200a Retinoblastoma 26379276 Novel miRNA-31 and miRNA-200a-Mediated Regulation of Retinoblastoma Proliferation. other hsa-mir-31 Retinoblastoma 26379276 Novel miRNA-31 and miRNA-200a-Mediated Regulation of Retinoblastoma Proliferation. other hsa-mir-375 Osteosarcoma 26381132 "Formononetin has inhibitory effects on the proliferation of U2SO cells, both in vitro and in vivo. This antitumor effect is directly correlated with formononetin concentration." other hsa-mir-130a Myeloma 26389804 "Together, our data suggest connection between lower level of microRNA-130a and extramedullary disease and prompt further work to evaluate this miRNA as a marker of extramedullary disease in multiple myeloma." other hsa-mir-122 "Carcinoma, Lung, Non-Small-Cell" 26389880 These results indicate that miR-122 would be a novel strategy for NSCLC radiation-therapy. other hsa-mir-143 Colorectal Carcinoma 26392389 "These findings warrant further studies to investigate the relationship between miR-143, FXYD3 and fluoropyrimidines, and the clinical utility of miR-143 as biomarker." other hsa-mir-221 Osteosarcoma 26397386 "Taken together, our results suggest that miR-221 enhances the proliferation,invasion and migration ability of osteosarcoma cells partly by suppressing PTEN." other hsa-mir-146b Glioma 26397753 "In conclusion, the inhibition of miR-146b may increase hypoxia-induced cardiomyocyte apoptosis." other hsa-mir-765 "Carcinoma, Breast" 26398721 These results provided novel insight into the regulatory mechanism of EMP3 in primary breast carcinoma. other hsa-mir-199a Breast Neoplasms 26399456 "Thus, miR-199a/b-3p functions as a tumor suppressor and has an important role in breast cancer metastasis through PAK4/MEK/ERK signaling pathway." other hsa-mir-199b Breast Neoplasms 26399456 "Thus, miR-199a/b-3p functions as a tumor suppressor and has an important role in breast cancer metastasis through PAK4/MEK/ERK signaling pathway." other hsa-mir-183 Breast Neoplasms 26400174 "In conclusion,our findings provide evidence that post-transcriptional studies of BRCA will benefit from transcending the one-locus-one-miRNA paradigm and taking into account all isoforms from each miRNA locus as well as the patient's race." other hsa-mir-23a Granulosa Cell Tumor 26400397 "These findings provide an improved understanding of the mechanisms underlying granulosa cell apoptosis, which could potentially be used for future clinical applications." other hsa-mir-27a Granulosa Cell Tumor 26400397 "These findings provide an improved understanding of the mechanisms underlying granulosa cell apoptosis, which could potentially be used for future clinical applications." other hsa-mir-183 "Carcinoma, Hepatocellular" 26400524 This study revealed a novel miR-21/miR-183-SOCS7 axis that might play an important role in modulating cell growth and invasion of HCC cells. other hsa-mir-21 "Carcinoma, Hepatocellular" 26400524 This study revealed a novel miR-21/miR-183-SOCS6 axis that might play an important role in modulating cell growth and invasion of HCC cells. other hsa-mir-1 Acute Kidney Failure 26400542 "Ramipril reduced cardiac hypertrophy, attenuated the increase in microRNA-212 and microRNA-132, and significantly increased microRNA-133 and microRNA-1 expression." other hsa-mir-146 Immune System Disease [unspecific] 26400897 "Present review is focused on the current knowledge about the action of medicaments,microRNA molecules, exosomes and related vesicles on macrophages leading to modulation of their biological activity." other hsa-mir-17 "Adenocarcinoma, Lung" 26402252 Identification of Biomarker and Co-Regulatory Motifs in Lung Adenocarcinoma Based on Differential Interactions. other hsa-mir-423 Colorectal Carcinoma 26402653 "In conclusion, our findings demonstrated a critical impact of miR-423-3p on CRC growth." other hsa-mir-532 Alzheimer Disease 26402772 "Although we could not consistently separate AD patients and controls in the whole group, we have found indications miRNA in CSF are able to reflect aging and perhaps also heterogeneity in AD. Further investigation requires optimizing RNA input, while maintaining strict age matching." other hsa-mir-30c "Carcinoma, Esophageal" 26402921 "Factors such as core promoter-binding protein (CPBP), nuclear factor of activated T-cells 1 (NFAT-1), miR-30c-5p, were located in the central hub of this network, highlighting their vital roles in esophageal tumorigenesis." other hsa-mir-34a Alcoholic Hepatitis 26403328 "These results constitute a demonstration of the altered regulation of miR-34a and miR-483-3p in the livers of AH and mice fed DDC where MDBs formed, providing further insight into the mechanism of MDB formation mediated by miR-34a and miR-483-3p in AH." other hsa-mir-483 Alcoholic Hepatitis 26403328 "These results constitute a demonstration of the altered regulation of miR-34a and miR-483-3p in the livers of AH and mice fed DDC where MDBs formed, providing further insight into the mechanism of MDB formation mediated by miR-34a and miR-483-3p in AH." other hsa-mir-34a "Carcinoma, Lung, Non-Small-Cell" 26406332 Aptamer-Dendrimer Bioconjugates for Targeted Delivery of miR-34a Expressing Plasmid and Antitumor Effects in Non-Small Cell Lung Cancer Cells. other hsa-mir-21 Breast Neoplasms 26411332 The miR-21-triggered self-assembly of DNA nanostructures can also serve as a remarkable signal amplification platform to achieve ultrasensitive detection of miR-21 from as low as 10 MCF-7 human breast cancer cells. other hsa-mir-124 Rhinosinusitis 26413631 The results from this study may further reveal the relationship between miRNA expressions and inflammation. These results can also provide an important mechanism (primitive data) on the occurrence of chronic sinusitis and nasal polyps. other hsa-mir-125b Rhinosinusitis 26413631 The results from this study may further reveal the relationship between miRNA expressions and inflammation. These results can also provide an important mechanism (primitive data) on the occurrence of chronic sinusitis and nasal polyps. other hsa-mir-146a Rhinosinusitis 26413631 The results from this study may further reveal the relationship between miRNA expressions and inflammation. These results can also provide an important mechanism (primitive data) on the occurrence of chronic sinusitis and nasal polyps. other hsa-mir-155 Rhinosinusitis 26413631 The results from this study may further reveal the relationship between miRNA expressions and inflammation. These results can also provide an important mechanism (primitive data) on the occurrence of chronic sinusitis and nasal polyps. other hsa-mir-181b Rhinosinusitis 26413631 The results from this study may further reveal the relationship between miRNA expressions and inflammation. These results can also provide an important mechanism (primitive data) on the occurrence of chronic sinusitis and nasal polyps. other hsa-mir-26b Rhinosinusitis 26413631 The results from this study may further reveal the relationship between miRNA expressions and inflammation. These results can also provide an important mechanism (primitive data) on the occurrence of chronic sinusitis and nasal polyps. other hsa-mir-92a Rhinosinusitis 26413631 The results from this study may further reveal the relationship between miRNA expressions and inflammation. These results can also provide an important mechanism (primitive data) on the occurrence of chronic sinusitis and nasal polyps. other hsa-let-7e "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. other hsa-mir-21 Renal Fibrosis 26415649 "Collectively, these data present a unified model for a key role for miR-21 in the regulation of renal tubular extracellular matrix (ECM) synthesis and accumulation and provide important insights into the molecular pathways implicated in the progression of DN." other hsa-let-7a Prostate Neoplasms 26415820 "In this review, we focus on the regulation of miRNAs in prostate cancer and their mechanisms which contribute to prostate carcinogenesis. The relation of miRNAs with androgen signaling is highlighted and the prospects of miRNAs for clinical therapies are discussed." other hsa-mir-145 Prostate Neoplasms 26415820 "In this review, we focus on the regulation of miRNAs in prostate cancer and their mechanisms which contribute to prostate carcinogenesis. The relation of miRNAs with androgen signaling is highlighted and the prospects of miRNAs for clinical therapies are discussed." other hsa-mir-18a Prostate Neoplasms 26415820 "In this review, we focus on the regulation of miRNAs in prostate cancer and their mechanisms which contribute to prostate carcinogenesis. The relation of miRNAs with androgen signaling is highlighted and the prospects of miRNAs for clinical therapies are discussed." other hsa-mir-218 Prostate Neoplasms 26415820 "In this review, we focus on the regulation of miRNAs in prostate cancer and their mechanisms which contribute to prostate carcinogenesis. The relation of miRNAs with androgen signaling is highlighted and the prospects of miRNAs for clinical therapies are discussed." other hsa-mir-23b Prostate Neoplasms 26415820 "In this review, we focus on the regulation of miRNAs in prostate cancer and their mechanisms which contribute to prostate carcinogenesis. The relation of miRNAs with androgen signaling is highlighted and the prospects of miRNAs for clinical therapies are discussed." other hsa-mir-296 Prostate Neoplasms 26415820 "In this review, we focus on the regulation of miRNAs in prostate cancer and their mechanisms which contribute to prostate carcinogenesis. The relation of miRNAs with androgen signaling is highlighted and the prospects of miRNAs for clinical therapies are discussed." other hsa-mir-429 Prostate Neoplasms 26415820 "In this review, we focus on the regulation of miRNAs in prostate cancer and their mechanisms which contribute to prostate carcinogenesis. The relation of miRNAs with androgen signaling is highlighted and the prospects of miRNAs for clinical therapies are discussed." other hsa-mir-497 Prostate Neoplasms 26415820 "In this review, we focus on the regulation of miRNAs in prostate cancer and their mechanisms which contribute to prostate carcinogenesis. The relation of miRNAs with androgen signaling is highlighted and the prospects of miRNAs for clinical therapies are discussed." other hsa-mir-134 Breast Neoplasms 26416415 miR-134 in extracellular vesicles reduces triple-negative breast cancer aggression and increases drug sensitivity. other hsa-mir-200b "Adenocarcinoma, Lung" 26416454 These results provide new evidence for the mechanisms governing the microRNA (miRNA)-ATG12 network and their possible contribution to autophagy modulation and LAD chemoresistance. other hsa-mir-574 Breast Neoplasms 26416693 Next generation sequencing profiling identifies miR-574-3p and miR-660-5p as potential novel prognostic markers for breast cancer. other hsa-mir-660 Breast Neoplasms 26416693 Next generation sequencing profiling identifies miR-574-3p and miR-660-5p as potential novel prognostic markers for breast cancer. other hsa-mir-4286 Pregnancy Complications [unspecific] 26418635 The findings highlight miRNAs in the human cervix as novel responders to maternal chemical exposure during pregnancy. other hsa-mir-575 Pregnancy Complications [unspecific] 26418635 The findings highlight miRNAs in the human cervix as novel responders to maternal chemical exposure during pregnancy. other hsa-let-7a Neoplasms [unspecific] 26420675 "Target-Catalyzed DNA Four-Way Junctions for CRET Imaging of MicroRNA,Concatenated Logic Operations, and Self-Assembly of DNA Nanohydrogels for Targeted Drug Delivery." other hsa-mir-29a Hepatitis C Virus Infection 26429314 "This study showed that HCV infection might abrogate NK cytotoxic potential through altering PU.1, NKG2D receptor and perforin molecules." other hsa-mir-222 Breast Neoplasms 26432333 exosomes transmit drug resistance through delivering miR-222. other hsa-mir-155 Sepsis 26433115 A higher level of miR-155 indicated a more severe condition and poorer prognosis in sepsis patients. The possible underlying mechanism could be that miR-155 induces an increased percentage of CD39(+) Tregs and thus immunosuppression. other hsa-mir-21 Glioblastoma 26433199 Dissociated microglia and monocytes/macrophages from tumor-bearing brains revealed increased levels of miR-21 and reduced levels of c-Myc mRNA. other hsa-mir-21 Glioma 26433199 Dissociated microglia and monocytes/macrophages from tumor-bearing brains revealed increased levels of miR-21 and reduced levels of c-Myc mRNA. other hsa-mir-204 Breast Neoplasms 26436206 Trichostatin A and Tamoxifen inhibit breast cancer cell growth by miR-204 and ER¦Á reducing AKT/mTOR pathway. other hsa-mir-196b "Leukemia, Myeloid, Acute" 26436590 "The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature." other hsa-mir-25 Thyroid Neoplasms 26437444 "Together, our data suggest that IL-23 induces migration and invasion in thyroid cancer cells by mediating the miR-25/SOCS4 signaling pathway." other hsa-mir-141 Neoplasms [unspecific] 26439017 Coupling hybridization chain reaction with catalytic hairpin assembly enables non-enzymatic and sensitive fluorescent detection of microRNA cancer biomarkers. other hsa-mir-143 Breast Neoplasms 26439035 "UCA1 can directly interact with miR-143, lower its expression and affect its downstream regulation. Therefore, the UCA1-miR-143 axis constitutes a part of the oncogenic role of UCA1 in breast cancer." other hsa-mir-23a Liver Neoplasms 26439986 we found expression of miR-23a was related to p53 functional status in the male-derived liver cell-lines other hsa-mir-212 Prostate Neoplasms 26439987 "In conclusion, our study indicates a functional role of miR-212 in PCa and suggests the development of miR-212 based therapies." other hsa-mir-16 "Colitis, Ulcerative" 26440311 "miR-16 suppression during the colitis-to-cancer sequence in colon epithelial cells, which was rescued by drinking Cl-amidine." other hsa-mir-10b Pancreatic Neoplasms 26444644 "Our findings suggest that this unique technique can be used to design novel diagnostic strategies for pancreatic and other cancers based on the direct quantitative measurement of plasma and exosome microRNAs, and can be readily extended to other diseases with identifiable microRNA signatures." other hsa-mir-210 Neoplasms [unspecific] 26446394 Potential Role of MicroRNA-210 as Biomarker in Human Cancers Detection: A Meta-Analysis. other hsa-mir-130b Osteosarcoma 26446495 "Taken together, our data indicated that high miR-130b level and low level of miR-218 are associated with poor clinicopathological characteristics.Furthermore, miR-130b may play a key role in the progression of osteosarcoma." other hsa-mir-218 Osteosarcoma 26446495 "Taken together, our data indicated that high miR-130b level and low level of miR-218 are associated with poor clinicopathological characteristics.Furthermore, miR-130b may play a key role in the progression of osteosarcoma." other hsa-mir-125b Coronary Artery Disease 26446730 "We found several synergistic effects between miR-125b and classical risk factors, such as age,sex, CR, FBG and HDL-C; the proportion of CHD attributable to the interaction of miR-125b and age was as high as 80%. Therefore, miR-125b was shown to play an important role in individual's susceptibility to developing CHD." other hsa-mir-26b Schizophrenia 26450699 "the notion that microRNAs fine-tune the amount of proteins acting in the same biological pathways in schizophrenia, giving further support to the emerging theory of competing endogenous RNAs." other hsa-mir-335 Schizophrenia 26450699 "the notion that microRNAs fine-tune the amount of proteins acting in the same biological pathways in schizophrenia, giving further support to the emerging theory of competing endogenous RNAs." other hsa-mir-221 Atherosclerosis 26451018 "Atherosclerotic plaque rupture is accompanied by a loss of miR-221 and miR-222 and an increase in p27Kip1 mRNA expression in the plaque shoulder,suggesting an association between these miRNAs and atherosclerotic plaque stability." other hsa-mir-222 Atherosclerosis 26451018 "Atherosclerotic plaque rupture is accompanied by a loss of miR-221 and miR-222 and an increase in p27Kip1 mRNA expression in the plaque shoulder,suggesting an association between these miRNAs and atherosclerotic plaque stability." other hsa-mir-106a Lung Neoplasms 26451608 These results encourage exploiting the MSC test for lung cancer monitoring in LDCT screening for lung cancer. other hsa-mir-17 Lung Neoplasms 26451608 These results encourage exploiting the MSC test for lung cancer monitoring in LDCT screening for lung cancer. other hsa-mir-197 Lung Neoplasms 26451608 These results encourage exploiting the MSC test for lung cancer monitoring in LDCT screening for lung cancer. other hsa-mir-19b Lung Neoplasms 26451608 These results encourage exploiting the MSC test for lung cancer monitoring in LDCT screening for lung cancer. other hsa-mir-486 Lung Neoplasms 26451608 These results encourage exploiting the MSC test for lung cancer monitoring in LDCT screening for lung cancer. other hsa-mir-92a Lung Neoplasms 26451608 These results encourage exploiting the MSC test for lung cancer monitoring in LDCT screening for lung cancer. other hsa-mir-506 "Carcinoma, Colon" 26452129 "Taking together, our study sheds light on the role of miR-506 as a suppressor for tumor growth and metastasis and raises the intriguing possibility that miR-506 may serve as a new potential marker for monitoring and treating colon cancer." other hsa-mir-1254 "Squamous Cell Carcinoma, Head and Neck" 26452218 "Together, we demonstrate the feasibility of using a miRNA signature to predict the clinical responsiveness of HNSCC radiotherapy." other hsa-mir-150 "Squamous Cell Carcinoma, Head and Neck" 26452218 "Together, we demonstrate the feasibility of using a miRNA signature to predict the clinical responsiveness of HNSCC radiotherapy." other hsa-mir-16 "Squamous Cell Carcinoma, Head and Neck" 26452218 "Together, we demonstrate the feasibility of using a miRNA signature to predict the clinical responsiveness of HNSCC radiotherapy." other hsa-mir-21 "Squamous Cell Carcinoma, Head and Neck" 26452218 "Together, we demonstrate the feasibility of using a miRNA signature to predict the clinical responsiveness of HNSCC radiotherapy." other hsa-mir-210 "Squamous Cell Carcinoma, Head and Neck" 26452218 "Together, we demonstrate the feasibility of using a miRNA signature to predict the clinical responsiveness of HNSCC radiotherapy." other hsa-mir-29 "Squamous Cell Carcinoma, Head and Neck" 26452218 "Together, we demonstrate the feasibility of using a miRNA signature to predict the clinical responsiveness of HNSCC radiotherapy." other hsa-mir-373 "Squamous Cell Carcinoma, Head and Neck" 26452218 "Together, we demonstrate the feasibility of using a miRNA signature to predict the clinical responsiveness of HNSCC radiotherapy." other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 26453197 Up-Regulation of miR-21 Expression Predicate Advanced Clinicopathological Features and Poor Prognosis in Patients with Non-Small Cell Lung Cancer. other hsa-mir-221 Astrocytoma 26454049 Loss of miR-221 function and cytotoxicity induced by the miR-221 DOXO MB provides combined therapeutic efficacy against cancers. other hsa-mir-106b Hepatitis B Virus Infection 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-106b Liver Cirrhosis 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-122 Hepatitis B Virus Infection 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-122 Liver Cirrhosis 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-181b Hepatitis B Virus Infection 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-181b Liver Cirrhosis 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-185 Hepatitis B Virus Infection 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-185 Liver Cirrhosis 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-18a Hepatitis B Virus Infection 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-18a Liver Cirrhosis 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-21 Hepatitis B Virus Infection 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-21 Liver Cirrhosis 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-29c Hepatitis B Virus Infection 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-29c Liver Cirrhosis 26456479 Our results provide important information for developing novel diagnostic tools for distinguishing chronic HBV hepatitis and their corresponding cirrhosis. other hsa-mir-5193 Hepatitis B Virus Infection 26456535 "Therefore, miR-5193 might be useful and have a vital role for inhibition of HBV replication in the future." other hsa-mir-101-2 Gastric Neoplasms 26458815 "Our expression analyses and in vitro functional assays suggest that miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in primary GCs as well as in GC-derived AGS cells." other hsa-mir-125b-2 Gastric Neoplasms 26458815 "Our expression analyses and in vitro functional assays suggest that miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in primary GCs as well as in GC-derived AGS cells." other hsa-mir-451a Gastric Neoplasms 26458815 "Our expression analyses and in vitro functional assays suggest that miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in primary GCs as well as in GC-derived AGS cells." other hsa-mir-19b Coronary Artery Disease 26459935 Therefore our results indicate that miR-19b plays a key role in the attenuation of TNF-¦Á-induced endothelial cell apoptosis and that this function is closely linked to the Apaf1/caspase-dependent pathway. other hsa-mir-650 Influenza 26460926 Together these findings reveal a novel link between miR-650 and the innate immune response in human MDDCs. other hsa-mir-214 "Adenocarcinoma, Lung" 26462018 "Collectively, this study uncovers a previously unappreciated miR-214-Sufu pathway in controlling EMT and metastasis of LAD and suggests that interfering with miR-214 and Sufu could be a viable approach to treat late stage metastatic LAD patients." other hsa-mir-9 "Leukemia, Myeloid, Acute" 26464168 Expression of a passenger miR-9* predicts favorable outcome in adults with acute myeloid leukemia less than 60 years of age. other hsa-mir-184 Glioma 26464691 Inhibitory effect of miR-184 on the potential of proliferation and invasion in human glioma and breast cancer cells in vitro. other hsa-mir-155 Lung Neoplasms 26467212 The candidate oncogene (MCRS1) promotes the growth of human lung cancer cells via the miR-155-Rb1 pathway. other hsa-mir-1290 Human Immunodeficiency Virus Infection 26469550 "Our study emphasizes the role of cellular miRNAs in HIV-1 latency regulation, and it suggests that inhibitors of miR-196b and miR-1290 could be used to activate latent HIV-1." other hsa-mir-196b Human Immunodeficiency Virus Infection 26469550 "Our study emphasizes the role of cellular miRNAs in HIV-1 latency regulation, and it suggests that inhibitors of miR-196b and miR-1290 could be used to activate latent HIV-1." other hsa-mir-21 Glioma 26473373 These results suggest that miR-21 is associated with regulation of the migratory ability and survival in human glioma cells. These findings suggest novel mechanisms of malignancy and new potential combinatorial strategies for the management of malignant glioma. other hsa-mir-27b Neoplasms [unspecific] 26473412 These findings show that miR-27b functions as a tumor suppressor by controlling ARFGEF1 and the paxillin/c-Src circuit at focal adhesions. other hsa-mir-21 Human Immunodeficiency Virus Infection 26473639 "These data reveal specific regulation of plasma miR-21 in HIV,HIV/HCV coinfection, and PAH and suggest that miR-21 may integrate complex disease-specific signaling in the setting of HIV infection." other hsa-mir-17 Neoplasms [unspecific] 26479035 "Our findings signify the dynamic and reciprocal cross-talk between tumour cells and the metastatic niche; importantly, they provide new opportunities for effective anti-metastasis therapies, especially of consequence for brain metastasis patients" other hsa-mir-18 Neoplasms [unspecific] 26479035 "Our findings signify the dynamic and reciprocal cross-talk between tumour cells and the metastatic niche; importantly, they provide new opportunities for effective anti-metastasis therapies, especially of consequence for brain metastasis patients" other hsa-mir-19a Neoplasms [unspecific] 26479035 "Our findings signify the dynamic and reciprocal cross-talk between tumour cells and the metastatic niche; importantly, they provide new opportunities for effective anti-metastasis therapies, especially of consequence for brain metastasis patients" other hsa-mir-19b Neoplasms [unspecific] 26479035 "Our findings signify the dynamic and reciprocal cross-talk between tumour cells and the metastatic niche; importantly, they provide new opportunities for effective anti-metastasis therapies, especially of consequence for brain metastasis patients" other hsa-mir-19b-1 Neoplasms [unspecific] 26479035 "Our findings signify the dynamic and reciprocal cross-talk between tumour cells and the metastatic niche; importantly, they provide new opportunities for effective anti-metastasis therapies, especially of consequence for brain metastasis patients" other hsa-mir-20a Neoplasms [unspecific] 26479035 "Our findings signify the dynamic and reciprocal cross-talk between tumour cells and the metastatic niche; importantly, they provide new opportunities for effective anti-metastasis therapies, especially of consequence for brain metastasis patients" other hsa-mir-92 Neoplasms [unspecific] 26479035 "Our findings signify the dynamic and reciprocal cross-talk between tumour cells and the metastatic niche; importantly, they provide new opportunities for effective anti-metastasis therapies, especially of consequence for brain metastasis patients" other hsa-mir-92-1 Neoplasms [unspecific] 26479035 "Our findings signify the dynamic and reciprocal cross-talk between tumour cells and the metastatic niche; importantly, they provide new opportunities for effective anti-metastasis therapies, especially of consequence for brain metastasis patients" other hsa-mir-125b-1 Neuroblastoma 26480000 "Identification of linc-NeD125, a novel long non coding RNA that hosts miR-125b-1 and negatively controls proliferation of human neuroblastoma cells." other hsa-mir-21 "Carcinoma, Esophageal" 26481465 "In this study, miR-21 was identified as an independent prognostic biomarker for DSS in patients with EAC whereas miR-21 failed to show independent prognostic significance in ESCC. High miR-375 was not associated with enhanced survival in either histology." other hsa-mir-375 "Carcinoma, Esophageal" 26481465 "In this study, miR-21 was identified as an independent prognostic biomarker for DSS in patients with EAC whereas miR-21 failed to show independent prognostic significance in ESCC. High miR-375 was not associated with enhanced survival in either histology." other hsa-mir-1236 Kidney Neoplasms 26481573 Kidney cancer: RNA activation in RCC: p21 and miR-1236 are a promising pair. other hsa-mir-17 "Carcinoma, Lung, Non-Small-Cell" 26482648 Our study indicates that miR-17 and miR-92 families play important roles in cisplatin resistance and can be used as potential biomarkers for better predicting the clinical response to platinum-based chemotherapy in NSCLC. other hsa-mir-92a "Carcinoma, Lung, Non-Small-Cell" 26482648 Our study indicates that miR-17 and miR-92 families play important roles in cisplatin resistance and can be used as potential biomarkers for better predicting the clinical response to platinum-based chemotherapy in NSCLC. other hsa-mir-22 Emphysema 26482970 MicroRNA miR-22 drives T(H)17 responses in emphysema. other hsa-mir-486 Coronary Artery Disease 26485305 MiR-486 and miR-92a Identified in Circulating HDL Discriminate between Stable and Vulnerable Coronary Artery Disease Patients. other hsa-mir-92a Coronary Artery Disease 26485305 MiR-486 and miR-92a Identified in Circulating HDL Discriminate between Stable and Vulnerable Coronary Artery Disease Patients. other hsa-mir-497 "Carcinoma, Lung, Non-Small-Cell" 26485685 "Together, our data demonstrate a previously unappreciated role for miR-497 in suppression of VEGF-A-mediated NSCLC cancer cell growth and invasion." other hsa-mir-21 Breast Neoplasms 26486006 Advances in Research on miR-21 and Breast Cancer. other hsa-mir-146a Leukemia 26487345 Transcription factor and miRNA co-regulatory network reveals shared and specific regulators in the development of B cell and T cell. other hsa-mir-20 Leukemia 26487345 Transcription factor and miRNA co-regulatory network reveals shared and specific regulators in the development of B cell and T cell. other hsa-mir-122 Kidney Injury 26489516 "In mice,miR-122-5p, miR-151a-3p and miR-382-5p specifically reported APAP toxicity -being unaffected by drug-induced kidney injury. Profiling of acetaminophen toxicity identified multiple miRNAs that report acute liver injury and potential biomarkers of drug-induced kidney injury." other hsa-mir-122 Liver Injury 26489516 "In mice,miR-122-5p, miR-151a-3p and miR-382-5p specifically reported APAP toxicity -being unaffected by drug-induced kidney injury. Profiling of acetaminophen toxicity identified multiple miRNAs that report acute liver injury and potential biomarkers of drug-induced kidney injury." other hsa-mir-151a Kidney Injury 26489516 "In mice,miR-122-5p, miR-151a-3p and miR-382-5p specifically reported APAP toxicity -being unaffected by drug-induced kidney injury. Profiling of acetaminophen toxicity identified multiple miRNAs that report acute liver injury and potential biomarkers of drug-induced kidney injury." other hsa-mir-151a Liver Injury 26489516 "In mice,miR-122-5p, miR-151a-3p and miR-382-5p specifically reported APAP toxicity -being unaffected by drug-induced kidney injury. Profiling of acetaminophen toxicity identified multiple miRNAs that report acute liver injury and potential biomarkers of drug-induced kidney injury." other hsa-mir-382 Kidney Injury 26489516 "In mice,miR-122-5p, miR-151a-3p and miR-382-5p specifically reported APAP toxicity -being unaffected by drug-induced kidney injury. Profiling of acetaminophen toxicity identified multiple miRNAs that report acute liver injury and potential biomarkers of drug-induced kidney injury." other hsa-mir-382 Liver Injury 26489516 "In mice,miR-122-5p, miR-151a-3p and miR-382-5p specifically reported APAP toxicity -being unaffected by drug-induced kidney injury. Profiling of acetaminophen toxicity identified multiple miRNAs that report acute liver injury and potential biomarkers of drug-induced kidney injury." other hsa-mir-122 Coronary Artery Disease 26490079 MicroRNA Biomarkers for Coronary Artery Disease other hsa-mir-96 Congenital Deafness 26490746 "Cx26-mediated intercellular communication is required for cochlear development and that deficiency of Cx26 can impair miRNA-mediated intercellular genetic communication in the cochlea, which may lead to cochlear developmental disorders and eventually congenital deafness as previously reported." other hsa-mir-26a Colorectal Carcinoma 26494299 microRNA-26a and -584 inhibit the colorectal cancer progression through inhibition of the binding of hnRNP A1-CDK6 mRNA. other hsa-mir-584 Colorectal Carcinoma 26494299 microRNA-26a and -584 inhibit the colorectal cancer progression through inhibition of the binding of hnRNP A1-CDK6 mRNA. other hsa-mir-130a "Leukemia, Myeloid, Chronic" 26494558 Functional studies of miR-130a on the inhibitory pathways of apoptosis in patients with chronic myeloid leukemia. other hsa-let-7d Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-100 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-107 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-129 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-132 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-136 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-146b Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-148a Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-152 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-15a Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-15b Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-160 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-192 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-193a Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-193b Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-194 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-200a Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-200b Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-203 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-205 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-26b Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-29b Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-30a Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-30b Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-31 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-335 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-497 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-664 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-703 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-709 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-801 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-923 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-93 Peritoneal Dialysis Failure 26495316 microRNA regulation of peritoneal cavity homeostasis in peritoneal dialysis. other hsa-mir-125a Multiple Myeloma 26496024 "Members of the miR-99b/let-7e/miR-125a cluster, or of its paralog, upregulated in t(4;14), were connected with the specific transcription factors PBX1 and CEBPA and several target genes." other hsa-mir-378 Colorectal Carcinoma 26496897 Lauric acid can improve the sensitization of Cetuximab in KRAS/BRAF mutated colorectal cancer cells by retrievable microRNA-378 expression. other hsa-mir-1 Breast Neoplasms 26497855 MicroRNA-1 down-regulates proliferation and migration of breast cancer stem cells by inhibiting the Wnt/¦Â-catenin pathway. other hsa-mir-135a Pain 26498117 "These results show that circulating miRNA predict persistent severe axial pain after MVC and suggest that they may be involved in the pathogenesis of post-traumatic musculoskeletal pain. However, further studies are needed to determine if these miRNA play a direct causal role." other hsa-mir-3613 Pain 26498117 "These results show that circulating miRNA predict persistent severe axial pain after MVC and suggest that they may be involved in the pathogenesis of post-traumatic musculoskeletal pain. However, further studies are needed to determine if these miRNA play a direct causal role." other hsa-mir-33a Influenza 26498766 "In conclusion, we found that miR-33a is a novel inhibitory factor for influenza A virus replication." other hsa-mir-21 Neoplasms [unspecific] 26503645 "Therefore,this study presents an improved method with shorten time to prepare a (99m)Tc radiolabeled AMO. In addition, it supports the role of (99m)Tc-AMO for noninvasive visualization of miR-21 in malignant tumors." other hsa-mir-122 Chronic Hepatitis C 26503793 We demonstrated a substantial and prolonged decrease in plasma miR-122 levels in patients dosed with miravirsen. Plasma levels of other miRNAs were not significantly affected by antagonising miR-122. other hsa-mir-146a Sjogren Syndrome 26505653 Dysregulated co-stimulatory molecule expression in a Sj?gren's syndrome mouse model with potential implications by microRNA-146a. other hsa-let-7d Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-106b Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-130a Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-146a Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-155 Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-15a Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-194 Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-221 Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-222 Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-223 Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-301a Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-30b Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-342 Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-4446 Epilepsy 26506013 This review highlights the immunological features underlying the pathogenesis of epileptic seizures and the possible miRNA mediated approaches for drug resistant epilepsies that modulate the immune-mediated pathogenesis. other hsa-mir-33a Breast Neoplasms 26507842 These findings identified miR-33a as a negative regulator of breast cancer cell proliferation and metastasis. other hsa-mir-34a Cardiomegaly 26508703 Neonatal HHR had higher cardiac telomerase activity and expression of Tert and miR-34a. other hsa-mir-223 Disease of Metabolism 26512640 "the roles of miR-223 during the processes of osteoclast and osteoblast differentiation, as well as the potential clinical applications of miR-223 in bone metabolism disorders." other hsa-mir-3619 "Carcinoma, Lung, Non-Small-Cell" 26512718 "Our data demonstrate a previously unappreciated role for miR-3619-5p,in suppression of ¦Â-catenin-mediated cancer growth and invasion in NSCLC cells,and highlight miR-3619-5p as a novel cancer suppressor in NSCLC." other hsa-mir-22 Breast Neoplasms 26512777 These results provide mechanistic insight into TIP60 regulation and evidence for the utility of the combination of TIP60 and miR-22 as prognostic indicator of breast cancer progression. other hsa-mir-371a Cardiomyopathy 26512958 "In conclusion, the presence of a g2252c polymorphism in the BAG3 3'-UTR determines loss of miR-371a-5p binding and results in an altered response to epi, potentially representing a new molecular mechanism that contributes to TTC pathogenesis." other hsa-mir-429 "Carcinoma, Gastric" 26513239 Our data suggest that miR-429 suppression in GC promotes Bcl-2-mediated cancer cell survival against chemotherapy-induced cell death.Re-expression of miR-429 levels in GC cells may enhance cancer apoptosis during chemotherapy. other hsa-mir-122 "Carcinoma, Hepatocellular" 26514126 The findings suggest that the export of miR-122 via AMSC exosomes represents a novel strategy to enhance HCC chemosensitivity. other hsa-mir-24 "Carcinoma, Pancreatic" 26517093 The miR-24-Bim pathway promotes tumor growth and angiogenesis in pancreatic carcinoma. other hsa-mir-155 "Lymphoma, Large B-Cell, Diffuse" 26523117 "In particular, it has been strongly implicated in the causation of diffuse large B-cell lymphomas." other hsa-mir-185 Atherosclerosis 26523989 "These findings reveal that miR-185 controls cholesterol homeostasis as a key posttranscriptional LDLR modulator in hepatic cells, providing novel insight into the regulatory mechanism for LDLR expression and the anti-atherosclerosis effect of miR-185-inhibitor." other hsa-mir-21 Lung Neoplasms 26525579 "These results, demonstrating the function of exosomal miR-21 from transformed HBE cells, provide a new perspective for intervention strategies to prevent carcinogenesis of lung cancer." other hsa-mir-200 "Carcinoma, Skin" 26527515 only a functionally coherent group consisting of the miR-200 family members and miR-205-5p displays a pattern of progressive co-downregulation from the early toward the most aggressive stages of carcinogenesis. other hsa-mir-124 Glioma 26530859 "In conclusion,miR-124 was found to suppress the migration and invasion of glioma cells in vitro via Capn4." other hsa-mir-4697 Gastric Neoplasms 26531872 "The expression of TM4SF5, CTD-2354A18.1 and miR-4697-3P is in balance at physiological conditions, however, the balance is disrupted by some situations, which may contribute to gastric cancer. GO analysis and Pathway analysis also showed TM4SF5 played an important role in proliferation,differentiation and apoptosis. Therefore, TM4SF5-miR-4697-3P- CTD-2354A18.1 may play a key role in the pathogenesis of gastric cancer (Tab. 2, Fig. 4, Ref. 30)." other hsa-mir-210 Melanoma 26536104 "methyl sulfone decreased expression of the master regulator of hypoxia, HIF-1α, and reduced levels of the glycolytic enzymes, PKM2, LDHA, GLUT1, the pro-angiogenic protein, VEGF, and the iron-sulfur metabolism molecules, miR-210 and transferrin, all of which promote metastasis." other hsa-mir-122 Hepatitis B Virus Infection 26541590 Mopping up miRNA: An integrated HBV transcript disrupts liver homeostasis by sequestering miR-122. other hsa-mir-10b "Squamous Cell Carcinoma, Oral" 26544609 "Results from both patient groups together stress the importance of miR196a-5p in OSCC malignancy in both never and ever smokers, and emphasize the overall similarity of miRNA expression in OSCCs in these two risk groups. It implies that there may be great similarity in etiology of OSCC in never and ever smokers and that classifying OSCC based on tobacco exposure may not be helpful in the clinic." other hsa-mir-196a "Squamous Cell Carcinoma, Oral" 26544609 "Results from both patient groups together stress the importance of miR196a-5p in OSCC malignancy in both never and ever smokers, and emphasize the overall similarity of miRNA expression in OSCCs in these two risk groups. It implies that there may be great similarity in etiology of OSCC in never and ever smokers and that classifying OSCC based on tobacco exposure may not be helpful in the clinic." other hsa-mir-31 "Squamous Cell Carcinoma, Oral" 26544609 "Results from both patient groups together stress the importance of miR196a-5p in OSCC malignancy in both never and ever smokers, and emphasize the overall similarity of miRNA expression in OSCCs in these two risk groups. It implies that there may be great similarity in etiology of OSCC in never and ever smokers and that classifying OSCC based on tobacco exposure may not be helpful in the clinic." other hsa-mir-125b Prostate Neoplasms 26544868 "Thus, the dual action of hsa-miR-125b as a tumor suppressor and hsa-miR-22 as an oncomiR contributed to prostate tumorigenesis by modulations in PI3K/AKT and MAPK/ERK signaling pathways, key pathways known to influence prostate cancer progression." other hsa-mir-17 Neoplasms [unspecific] 26545119 "In summary, our data demonstrate that vFLIP and vCyclin induce the oncogenic miR-17-92 cluster in endothelial cells and thereby interfere with the TGF-¦Â signaling pathway. Manipulation of the TGF-¦Â pathway via host miRNAs represents a novel mechanism that may be important for KSHV tumorigenesis and angiogenesis, a hallmark of KS." other hsa-mir-18 Neoplasms [unspecific] 26545119 "In summary, our data demonstrate that vFLIP and vCyclin induce the oncogenic miR-17-92 cluster in endothelial cells and thereby interfere with the TGF-¦Â signaling pathway. Manipulation of the TGF-¦Â pathway via host miRNAs represents a novel mechanism that may be important for KSHV tumorigenesis and angiogenesis, a hallmark of KS." other hsa-mir-19a Neoplasms [unspecific] 26545119 "In summary, our data demonstrate that vFLIP and vCyclin induce the oncogenic miR-17-92 cluster in endothelial cells and thereby interfere with the TGF-¦Â signaling pathway. Manipulation of the TGF-¦Â pathway via host miRNAs represents a novel mechanism that may be important for KSHV tumorigenesis and angiogenesis, a hallmark of KS." other hsa-mir-19b-1 Neoplasms [unspecific] 26545119 "In summary, our data demonstrate that vFLIP and vCyclin induce the oncogenic miR-17-92 cluster in endothelial cells and thereby interfere with the TGF-¦Â signaling pathway. Manipulation of the TGF-¦Â pathway via host miRNAs represents a novel mechanism that may be important for KSHV tumorigenesis and angiogenesis, a hallmark of KS." other hsa-mir-20a Neoplasms [unspecific] 26545119 "In summary, our data demonstrate that vFLIP and vCyclin induce the oncogenic miR-17-92 cluster in endothelial cells and thereby interfere with the TGF-¦Â signaling pathway. Manipulation of the TGF-¦Â pathway via host miRNAs represents a novel mechanism that may be important for KSHV tumorigenesis and angiogenesis, a hallmark of KS." other hsa-mir-92-1 Neoplasms [unspecific] 26545119 "In summary, our data demonstrate that vFLIP and vCyclin induce the oncogenic miR-17-92 cluster in endothelial cells and thereby interfere with the TGF-¦Â signaling pathway. Manipulation of the TGF-¦Â pathway via host miRNAs represents a novel mechanism that may be important for KSHV tumorigenesis and angiogenesis, a hallmark of KS." other hsa-mir-155 Down Syndrome 26546125 "The lentiviral miRNA-sponge strategy demonstrated the genome-wide regulatory effects of miR-155 and miR-802. Furthermore, the analysis combining predicted candidates and experimental transcriptomic data proved to retrieve genes with potential significance in DS-hippocampal phenotype bridging with DS other neurological-associated diseases such as Alzheimer's disease." other hsa-mir-802 Down Syndrome 26546125 "The lentiviral miRNA-sponge strategy demonstrated the genome-wide regulatory effects of miR-155 and miR-802. Furthermore, the analysis combining predicted candidates and experimental transcriptomic data proved to retrieve genes with potential significance in DS-hippocampal phenotype bridging with DS other neurological-associated diseases such as Alzheimer's disease." other hsa-mir-200 Neoplasms [unspecific] 26547426 "On the basis of these findings,we believe that this method has great potential for quantitative detection of miRNA in biomedical research and early clinical diagnostics." other hsa-mir-155 "Leukemia, Myelogenous, Chronic, BCR-ABL Positive" 26548770 Analysis of microRNA and gene networks in human chronic myelogenous leukemia. other hsa-mir-146a Neoplasms [unspecific] 26549232 Together our results uncover miRNAs as yet another negative mechanism controlling Merlin tumor suppressor functions. other hsa-mir-223 Prostate Neoplasms 26552919 "For the first time, we disclose that celastrol could induce miR-223 in breast and prostate cancer cells, and that inhibiting miR-223 could further reduce the living cells in celastrol-treated cancer cell lines. We thus provide a novel way to increase celastrol's anti-cancer effects." other hsa-mir-218 Lung Neoplasms 26553452 Our findings revealed an integrative tumor suppressor function of miR-218 in lung carcinogenesis and metastasis. other hsa-mir-340 Melanoma 26554847 "This is the first study showing the relationship between miR-340-5p and expression of ABCB5, a transmembrane transporter involved in drug resistance considered as a marker of melanoma stem-like cells." other hsa-mir-7 "Carcinoma, Lung, Non-Small-Cell" 26557760 We found that miR-7 significantly decreased the IC50 of gefitinib and inhibited cell growth other hsa-mir-34 Cardiovascular Diseases [unspecific] 26559089 MicroRNA-34 Family and Its Role in Cardiovascular Disease. other hsa-mir-146a Psoriasis 26559308 "It is found that genetic polymorphisms related to some of specific miRNAs, miR-146a for example, are associated with psoriasis susceptibility." other hsa-mir-21 Glioblastoma 26559642 Nanoparticle-Delivered Antisense MicroRNA-21 Enhances the Effects of Temozolomide on Glioblastoma Cells. other hsa-mir-214 Multiple Sclerosis 26563334 "Our data suggest that miR-27a may probably inhibit negative regulators of Th17 cell differentiation, thus promoting its differentiation while miR-214 has an adverse effect." other hsa-mir-27a Multiple Sclerosis 26563334 "Our data suggest that miR-27a may probably inhibit negative regulators of Th17 cell differentiation, thus promoting its differentiation while miR-214 has an adverse effect." other hsa-mir-377 Myocardial Infarction 26564601 "The present study is timely because the field is eagerly awaiting the results of the large phase III BAMI (Bone Marrow-Derived Mononuclear Cells on All-Cause Mortality in Myocardial Infarction; NCT01569178) clinical trial. If this clinical trial turns out positively, approaches such as the one developed by Joladarashi et al. will have additional relevance to the field." other hsa-mir-130 Pulmonary Hypertension 26565914 Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit. other hsa-mir-301 Pulmonary Hypertension 26565914 Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit. other hsa-mir-124 Atrial Fibrillation 26567235 "In conclusion, the microRNA regulatory network sheds new light on the molecular mechanism of AF with this non-coding regulated model." other hsa-mir-183 Atrial Fibrillation 26567235 "In conclusion, the microRNA regulatory network sheds new light on the molecular mechanism of AF with this non-coding regulated model." other hsa-mir-192 Atrial Fibrillation 26567235 "In conclusion, the microRNA regulatory network sheds new light on the molecular mechanism of AF with this non-coding regulated model." other hsa-mir-215 Atrial Fibrillation 26567235 "In conclusion, the microRNA regulatory network sheds new light on the molecular mechanism of AF with this non-coding regulated model." other hsa-mir-26b Atrial Fibrillation 26567235 "In conclusion, the microRNA regulatory network sheds new light on the molecular mechanism of AF with this non-coding regulated model." other hsa-mir-355p Atrial Fibrillation 26567235 "In conclusion, the microRNA regulatory network sheds new light on the molecular mechanism of AF with this non-coding regulated model." other hsa-mir-21 "Carcinoma, Nasopharyngeal" 26568302 LMP1 greatly increased expression of miR-21 and downregulated expression of the miR-21 target other hsa-mir-218 Glioma 26572167 MiR-218-5p inhibits the stem cell properties and invasive ability of the A2B5+CD133- subgroup of human glioma stem cells. other hsa-mir-21 "Carcinoma, Renal Cell, Clear-Cell" 26572589 "Thus, a single miRNA may have an impact on the formation of highly tumorigenic cancer spheres in kidney cancer." other hsa-mir-148b Kidney Neoplasms 26573018 The present study therefore suggested that miR-148b exerts an oncogenic function by enhancing the proliferation and apoptosis of renal cancer cells by inhibiting the MAPK/JNK pathway. other hsa-mir-122 Liver Diseases [unspecific] 26574140 "miR-122 increased with moderate ethanol consumption, but the fold change was modest. As increases with acetaminophen toxicity are 100- to 10000-fold, moderate ethanol intoxication is unlikely to confound the use of this biomarker of hepatotoxicity." other hsa-mir-122 Schizophrenia 26575446 Circulating miRNA biomarkers for schizophrenia other hsa-mir-130 Schizophrenia 26575446 Circulating miRNA biomarkers for schizophrenia other hsa-mir-652 Schizophrenia 26575446 Circulating miRNA biomarkers for schizophrenia other hsa-mir-145 Prostate Neoplasms 26582710 Re: A Feedback Regulation between miR-145 and DNA Methyltransferase 3b in Prostate Cancer Cell and Their Responses to Irradiation. other hsa-mir-34a Vascular Disease [unspecific] 26582729 overexpression of a miR-34a mimic prevents metformin-mediated protection. other hsa-mir-494 Atherosclerosis 26583674 Treatment with GSO-494 results in smaller atherosclerotic lesions with increased plaque stability. Inhibition of miR-494 may decrease the risk of surgical complications or even avert endarterectomy surgery in some cases. other hsa-mir-122 Hepatitis C Virus Infection 26587035 characteristics of the miR-122 and Let-7 families further highlight the suitability of tree shrew as the animal model in HCV research. other hsa-let-7 Ischemic Heart Disease 26588727 Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer. other hsa-mir-17 Perlman Syndrome 26598317 "Our findings not only provide a novel insight into the molecular mechanisms of macrosomia, but also the clinical value of miR-17-92 cluster as a predictive biomarker for macrosomia." other hsa-mir-18 Perlman Syndrome 26598317 "Our findings not only provide a novel insight into the molecular mechanisms of macrosomia, but also the clinical value of miR-17-92 cluster as a predictive biomarker for macrosomia." other hsa-mir-19a Perlman Syndrome 26598317 "Our findings not only provide a novel insight into the molecular mechanisms of macrosomia, but also the clinical value of miR-17-92 cluster as a predictive biomarker for macrosomia." other hsa-mir-19b-1 Perlman Syndrome 26598317 "Our findings not only provide a novel insight into the molecular mechanisms of macrosomia, but also the clinical value of miR-17-92 cluster as a predictive biomarker for macrosomia." other hsa-mir-20a Perlman Syndrome 26598317 "Our findings not only provide a novel insight into the molecular mechanisms of macrosomia, but also the clinical value of miR-17-92 cluster as a predictive biomarker for macrosomia." other hsa-mir-92-1 Perlman Syndrome 26598317 "Our findings not only provide a novel insight into the molecular mechanisms of macrosomia, but also the clinical value of miR-17-92 cluster as a predictive biomarker for macrosomia." other hsa-mir-150 "Squamous Cell Carcinoma, Esophageal" 26606907 "Taken together, our results highlight the involvement of miRNAs in ribosomal regulation during tumorigenesis." other hsa-mir-383 "Squamous Cell Carcinoma, Esophageal" 26606907 "Taken together, our results highlight the involvement of miRNAs in ribosomal regulation during tumorigenesis." other hsa-mir-190a "Carcinoma, Hepatocellular" 26608035 Our results reveal the involvement of miR-190a-treRNA axis in hepatoma progression and shed light on lncRNA-based cancer therapies for hepatoma patients at high risk of metastasis. other hsa-mir-21 Neoplasms [unspecific] 26610525 induction of miR-21 by type I IFN other hsa-mir-1 Bladder Outlet Obstruction 26612603 "We discuss known and predicted functions of miR-1, miR-29, miR-30, miR-132/212, miR-204 and miR-221, all of which change in BOO." other hsa-mir-132 Bladder Outlet Obstruction 26612603 "We discuss known and predicted functions of miR-1, miR-29, miR-30, miR-132/212, miR-204 and miR-221, all of which change in BOO." other hsa-mir-204 Bladder Outlet Obstruction 26612603 "We discuss known and predicted functions of miR-1, miR-29, miR-30, miR-132/212, miR-204 and miR-221, all of which change in BOO." other hsa-mir-212 Bladder Outlet Obstruction 26612603 "We discuss known and predicted functions of miR-1, miR-29, miR-30, miR-132/212, miR-204 and miR-221, all of which change in BOO." other hsa-mir-221 Bladder Outlet Obstruction 26612603 "We discuss known and predicted functions of miR-1, miR-29, miR-30, miR-132/212, miR-204 and miR-221, all of which change in BOO." other hsa-mir-29 Bladder Outlet Obstruction 26612603 "We discuss known and predicted functions of miR-1, miR-29, miR-30, miR-132/212, miR-204 and miR-221, all of which change in BOO." other hsa-mir-30 Bladder Outlet Obstruction 26612603 "We discuss known and predicted functions of miR-1, miR-29, miR-30, miR-132/212, miR-204 and miR-221, all of which change in BOO." other hsa-mir-34a Ewing Sarcoma 26616853 CD99 counteracts EWS-FLI1 in controlling NF-¦ÊB signaling through the miR-34a other hsa-mir-106b Colorectal Carcinoma 26617763 "Taken together, these findings demonstrated that miR-106b knockdown could induce EMT which conferring cells migratory and invasive properties but could not accomplish distant metastatic colonization efficiently." other hsa-mir-506 "Carcinoma, Esophageal" 26617801 "Taken together, our data identify a new role of miR-506 in esophageal cancer involving CREB1 suppression." other hsa-mir-223 "Carcinoma, Cervical" 26617846 "In conclusion, miR-223 inhibited cell metastasis of human cervical cancer by modulating epithelial-mesenchymal transition." other hsa-mir-146a "Squamous Cell Carcinoma, Head and Neck" 26621153 Characterizing the expression of miR-146a and miR-155 and their functional role in tumor biology underlined significantly their proliferation and migration potential suggesting relevance as potential prognostic markers in HNSCC. other hsa-mir-155 "Squamous Cell Carcinoma, Head and Neck" 26621153 Characterizing the expression of miR-146a and miR-155 and their functional role in tumor biology underlined significantly their proliferation and migration potential suggesting relevance as potential prognostic markers in HNSCC. other hsa-mir-125a Neoplasms [unspecific] 26625740 This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage. other hsa-mir-125b Neoplasms [unspecific] 26625740 This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage. other hsa-mir-15a Neoplasms [unspecific] 26625740 This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage. other hsa-mir-16-1 Neoplasms [unspecific] 26625740 This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage. other hsa-mir-195 Neoplasms [unspecific] 26625740 This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage. other hsa-mir-205 Neoplasms [unspecific] 26625740 This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage. other hsa-mir-24-2 Neoplasms [unspecific] 26625740 This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage. other hsa-mir-29 Neoplasms [unspecific] 26625740 This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage. other hsa-mir-34a Neoplasms [unspecific] 26625740 This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage. other hsa-mir-365-2 Neoplasms [unspecific] 26625740 This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage. other hsa-mir-504 Neoplasms [unspecific] 26625740 This review covers roles of microRNAs and chemopreventive agents and makes an attempt at outlining possible partnerships in maximizing cancer cell death with minimal normal cell damage. other hsa-let-7d Lung Neoplasms 26627242 "microRNA classifiers are powerful diagnostic/prognostic tools in ALK-, EGFR-, and KRAS-driven lung cancers." other hsa-mir-769 Lung Neoplasms 26627242 "microRNA classifiers are powerful diagnostic/prognostic tools in ALK-, EGFR-, and KRAS-driven lung cancers." other hsa-mir-138 "Adenocarcinoma, Lung" 26631041 we discovered that α-solanine could affect the expression of miR-138 and focal adhesion kinase other hsa-mir-21 Graft-Versus-Host Disease 26631756 MicroRNA-21 deficiency protects from lupus-like autoimmunity in the chronic graft-versus-host disease model of systemic lupus erythematosus. other hsa-mir-197 Gastric Neoplasms 26632693 Associations of Il-1 Family-Related Polymorphisms With Gastric Cancer Risk and the Role of Mir-197 In Il-1f5 Expression. other hsa-mir-145 Diabetes Mellitus 26636106 "CRT may lead to left ventricular reverse remodeling, with LVEF, NYHA functional class, and 6MWT improvement in both diabetic and nondiabetic adult patients.These observations have been confirmed by other authors in a population of elderly diabetic patients, a part of 6MWT improvement, that is not CRT-induced in elderly diabetes." other hsa-mir-26b Diabetes Mellitus 26636106 "CRT may lead to left ventricular reverse remodeling, with LVEF, NYHA functional class, and 6MWT improvement in both diabetic and nondiabetic adult patients.These observations have been confirmed by other authors in a population of elderly diabetic patients, a part of 6MWT improvement, that is not CRT-induced in elderly diabetes." other hsa-mir-29a Diabetes Mellitus 26636106 "CRT may lead to left ventricular reverse remodeling, with LVEF, NYHA functional class, and 6MWT improvement in both diabetic and nondiabetic adult patients.These observations have been confirmed by other authors in a population of elderly diabetic patients, a part of 6MWT improvement, that is not CRT-induced in elderly diabetes." other hsa-mir-92a Diabetes Mellitus 26636106 "CRT may lead to left ventricular reverse remodeling, with LVEF, NYHA functional class, and 6MWT improvement in both diabetic and nondiabetic adult patients.These observations have been confirmed by other authors in a population of elderly diabetic patients, a part of 6MWT improvement, that is not CRT-induced in elderly diabetes." other hsa-mir-200c Lymphoma 26639163 Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma. other hsa-mir-203 Lymphoma 26639163 Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma. other hsa-mir-31 Lymphoma 26639163 Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma. other hsa-mir-381 "Carcinoma, Lung, Non-Small-Cell" 26640150 ADAR1 overexpression enhances the editing frequencies of target transcripts such as NEIL1 and miR-381. other hsa-mir-210 Ovarian Neoplasms 26640557 "miR-923, miR-1246, miR-149*, miR-638 and miR-210 were upregulated and miR-99a, miR-181a-2* and miR-339-5p were downregulated following bafilomycin A1 treatment." other hsa-mir-127 Lymphoma 26640803 "The result of cross validation indicates that MiRNAClassify significantly outperforms other methods and models. In addition, the newly added pre-miRNAs are used to further evaluate the ability of these methods to discover novel pre-miRNAs. MiRNAClassify still achieves consistently superior performance and can discover more pre-miRNAs." other hsa-mir-192 Breast Neoplasms 26642352 MiR-192-Mediated Positive Feedback Loop Controls the Robustness of Stress-Induced p53 Oscillations in Breast Cancer Cells. other hsa-mir-485 Viral Infectious Disease 26645583 These findings highlight the dual role of miR-485 in preventing spurious activation of antiviral signaling and restricting influenza virus infection. other hsa-mir-1307 Liver Neoplasms 26646011 Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs. other hsa-mir-21 Liver Neoplasms 26646011 Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs. other hsa-mir-224 Liver Neoplasms 26646011 Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs. other hsa-mir-27 Liver Neoplasms 26646011 Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs. other hsa-mir-33 Liver Neoplasms 26646011 Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs. other hsa-mir-144 Allergic Asthma 26646558 "Together, the pathogenesis of OVA-induced asthma is highly associated with oxidative stress,and DAS may be an effective supplement to alleviate this disease." other hsa-mir-34a Allergic Asthma 26646558 "Together, the pathogenesis of OVA-induced asthma is highly associated with oxidative stress,and DAS may be an effective supplement to alleviate this disease." other hsa-mir-34b Allergic Asthma 26646558 "Together, the pathogenesis of OVA-induced asthma is highly associated with oxidative stress,and DAS may be an effective supplement to alleviate this disease." other hsa-mir-335 Prostate Neoplasms 26647850 "These findings suggested that miR-335 and -543 are associated with bone metastasis of PCa and indicated that they may have important roles in the bone metastasis, which may also be clinically used as novel biomarkers in discriminating the different stages of human PCa and predicting bone metastasis." other hsa-mir-543 Prostate Neoplasms 26647850 "These findings suggested that miR-335 and -543 are associated with bone metastasis of PCa and indicated that they may have important roles in the bone metastasis, which may also be clinically used as novel biomarkers in discriminating the different stages of human PCa and predicting bone metastasis." other hsa-mir-122 Infertility 26648257 Altered miRNA Signature of Developing Germ-cells in Infertile Patients Relates to the Severity of Spermatogenic Failure and Persists in Spermatozoa. other hsa-mir-34c Infertility 26648257 Altered miRNA Signature of Developing Germ-cells in Infertile Patients Relates to the Severity of Spermatogenic Failure and Persists in Spermatozoa. other hsa-mir-449a Infertility 26648257 Altered miRNA Signature of Developing Germ-cells in Infertile Patients Relates to the Severity of Spermatogenic Failure and Persists in Spermatozoa. other hsa-mir-34a Neoplasms [unspecific] 26648462 "MiR-34a is associated with G1 cell cycle arrest, senescence and apoptosis, thereby possessing a tumor suppressor activity." other hsa-let-7g "Carcinoma, Esophageal" 26655271 BAG3-mediated miRNA let-7g and let-7i inhibit proliferation and enhance apoptosis of human esophageal carcinoma cells by targeting the drug transporter ABCC10. other hsa-let-7i "Carcinoma, Esophageal" 26655271 BAG3-mediated miRNA let-7g and let-7i inhibit proliferation and enhance apoptosis of human esophageal carcinoma cells by targeting the drug transporter ABCC10. other hsa-mir-122 "Carcinoma, Hepatocellular" 26655273 Our data imply that an intimate correlation between miR-122 and IGF-1R abnormal expression is a critical determinant of sorafenib tolerance. other hsa-mir-124 Ovarian Neoplasms 26655797 A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression. other hsa-mir-155 Ovarian Neoplasms 26655797 A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression. other hsa-mir-181b Ovarian Neoplasms 26655797 A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression. other hsa-mir-517a Ovarian Neoplasms 26655797 A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression. other hsa-mir-323 Glioma 26656446 MiRNA-323-5p inhibited human cerebral glioma U373 cell proliferation and promoted its apoptosis by reducing IGF-1R. other hsa-mir-122 Inflammation 26657215 "In addition to the classical Jak-Stat antiviral signaling pathway,IFN-¦Ë1 inhibits HCV replication through the suppression of miRNA-122 transcription via an inflammatory Stat 3-HNF4¦Á feedback loop. Inflammatory feedback circuits activated by IFNs during chronic inflammation expose non-responders to the risk of hepatocellular carcinoma." other hsa-mir-17 Diabetes Mellitus 26660634 miR-17 repression mediates the pro-apoptotic effect of high glucose other hsa-mir-372 "Adenocarcinoma, Prostate" 26662140 "hsa-miR-372 and miR-373, we suggest that miR-ch21 down-regulation might be the result of specific silencing of miR genes mapped to chromosome 21" other hsa-mir-27a Breast Neoplasms 26662313 knockdown of miR-27a by the specific inhibitors significantly increased the sensitivity of T-47D cells to cisplatin (CDDP) treatment. other hsa-mir-126 Atherosclerosis 26662986 "In particular, the specific roles of miR-126 and miR-143/145, master regulators of EC and VSMC function, respectively, are deeply explored." other hsa-mir-423 "Carcinoma, Hepatocellular" 26663009 miR423-5p contributed to the tumorigenesis and progression of HCC.It could be a new predictor in HCC patients beyond the Milan criteria and would help to improve patient outcomes and enlarge recipient pools of liver transplantation. other hsa-mir-122 Liver Diseases [unspecific] 26669080 Biological function of miR-122 and its relationship with liver diseases. other hsa-mir-34c Colorectal Carcinoma 26674205 "Res suppressed CRC by specifically activating miR-34c-KITLG in vitro and in vivo; and the effect was strengthened in the presence of p53. Besides, Resexerted a synergistic effect with Oxa in a miR-34c dependent manner. We also suggested that Res-increased miR-34c could interfere IL-6-triggered CRC progression." other hsa-mir-155 Autoimmune Diseases [unspecific] 26674874 We have shown that mice in which the miR-155 host gene (MIR155HG) has been deactivated are resistant to EAE. other hsa-let-7 Hematologic Neoplasms 26676759 "Taken together, our results reveal a previously unknown mechanism by which Myc induces apoptosis independent of the p53 pathway and as a response to HDACi in malignant hematopoietic cells." other hsa-mir-15 Hematologic Neoplasms 26676759 "Taken together, our results reveal a previously unknown mechanism by which Myc induces apoptosis independent of the p53 pathway and as a response to HDACi in malignant hematopoietic cells." other hsa-let-7d Osteosarcoma 26679758 Let-7d miRNA Shows Both Antioncogenic and Oncogenic Functions in Osteosarcoma-Derived 3AB-OS Cancer Stem Cells. other hsa-mir-203 "Carcinoma, Lung, Non-Small-Cell" 26683818 "Our results suggest that LASP-1, mediated by miR-203,has crucial functions in the proliferation, migration and invasion of NSCLC." other hsa-mir-196a "Carcinoma, Pancreatic" 26683934 "MiRNA-196a level may be a promising prognostic marker of recurrence in resected PanNETs, although further experimental investigation would be required." other hsa-mir-520g Brain Neoplasms 26687818 Tissue Factor Regulation by miR-520g in Primitive Neuronal Brain Tumor Cells: A Possible Link between Oncomirs and the Vascular Tumor Microenvironment. other hsa-mir-373 Laryngeal Neoplasms 26688807 Association of Polymorphic Variants of miRNA Processing Genes with Larynx Cancer Risk in a Polish Population. other hsa-mir-202 Multiple Myeloma 26689580 miR-202 over-expression sensitized MM cells to bortezomib (Bort) but less to Thalidomide (Thal) and dexamethasone (Dex). other hsa-let-7a Melanoma 26693896 "Aberrant activation of some known miRNAs, e.g. let-7a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR-214, miR-221 and 222, has been recognised to be linked with melanoma-associated genes" other hsa-mir-221 Melanoma 26693896 "Aberrant activation of some known miRNAs, e.g. let-7a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR-214, miR-221 and 222, has been recognised to be linked with melanoma-associated genes" other hsa-mir-125b Alzheimer Disease 26694372 MicroRNA (miRNA) Signaling in the Human CNS in Sporadic Alzheimer's Disease (AD)-Novel and Unique Pathological Features. other hsa-mir-146a Alzheimer Disease 26694372 MicroRNA (miRNA) Signaling in the Human CNS in Sporadic Alzheimer's Disease (AD)-Novel and Unique Pathological Features. other hsa-mir-155 Alzheimer Disease 26694372 MicroRNA (miRNA) Signaling in the Human CNS in Sporadic Alzheimer's Disease (AD)-Novel and Unique Pathological Features. other hsa-mir-34a Alzheimer Disease 26694372 MicroRNA (miRNA) Signaling in the Human CNS in Sporadic Alzheimer's Disease (AD)-Novel and Unique Pathological Features. other hsa-mir-7 Alzheimer Disease 26694372 MicroRNA (miRNA) Signaling in the Human CNS in Sporadic Alzheimer's Disease (AD)-Novel and Unique Pathological Features. other hsa-mir-9 Alzheimer Disease 26694372 MicroRNA (miRNA) Signaling in the Human CNS in Sporadic Alzheimer's Disease (AD)-Novel and Unique Pathological Features. other hsa-mir-1246 "Carcinoma, Lung, Non-Small-Cell" 26711929 "Anti-miR-1246 and anti-miR-1290 suppressed proliferation, sphere-formation, colony formation and invasion of NSCLC.CSCs-associated miR-1246, or miR-1290 may be important in the invasion or metastasis of NSCLC." other hsa-mir-1290 "Carcinoma, Lung, Non-Small-Cell" 26711929 "Anti-miR-1246 and anti-miR-1290 suppressed proliferation, sphere-formation, colony formation and invasion of NSCLC.CSCs-associated miR-1246, or miR-1290 may be important in the invasion or metastasis of NSCLC." other hsa-mir-21 Colorectal Carcinoma 26712035 "miR-21 followed by miR-34, miR-200 and miR-215 are the most reported miRNAs to have roles in colon CSC regulation." other hsa-mir-215 Colorectal Carcinoma 26712035 "miR-21 followed by miR-34, miR-200 and miR-215 are the most reported miRNAs to have roles in colon CSC regulation." other hsa-mir-208b Acute Myocardial Infarction 26712201 none other hsa-mir-21 Neoplasms [unspecific] 26716902 LIF induces miR-21 expression through the activation of STAT3. other hsa-mir-34a Neoplasms [unspecific] 26718338 MicroRNA-34a Negatively Regulates Efferocytosis by Tissue Macrophages in Part via SIRT1. other hsa-mir-29b Multiple Myeloma 26718793 genistein could suppress the protein level of NF-κB and promote the expression of miR-29b in U266 cells. other hsa-mir-106a Gastric Neoplasms 26722506 Diagnostic significance of miR-106a in gastric cancer. other hsa-mir-340 Gastric Neoplasms 26722508 Effect of miR-340 on gastric cancer cell proliferation and apoptosis. other hsa-mir-141 Ovarian Neoplasms 26725650 "These mechanisms have significant relevance in ovarian cancers and stress response, pathophysiological conditions in which miR-200c/141 exert key functions." other hsa-mir-200c Ovarian Neoplasms 26725650 "These mechanisms have significant relevance in ovarian cancers and stress response, pathophysiological conditions in which miR-200c/141 exert key functions." other hsa-mir-149 "Leukemia, Lymphoblastic, Acute" 26725775 miRNA-149* promotes cell proliferation and suppresses apoptosis by mediating JunB in T-cell acute lymphoblastic leukemia. other hsa-mir-146a "Colitis, Ulcerative" 26730791 "Our results suggest that microRNAs may serve as a novel regulator in function and homoeostasis of UC Treg cells, providing a key role for them in pathophysiology of UC." other hsa-mir-155 "Colitis, Ulcerative" 26730791 "Our results suggest that microRNAs may serve as a novel regulator in function and homoeostasis of UC Treg cells, providing a key role for them in pathophysiology of UC." other hsa-mir-21 "Colitis, Ulcerative" 26730791 "Our results suggest that microRNAs may serve as a novel regulator in function and homoeostasis of UC Treg cells, providing a key role for them in pathophysiology of UC." other hsa-mir-125 Malignant Neoplasms [unspecific] 26731991 "These results suggest that different members of the miR-125 family may have different functions in various cancers. Furthermore, miR-125a or miR-125b may be important clinical prognostic biomarkers for cancer patients." other hsa-mir-143 Inflammation 26739093 Staphylococcal LTA-Induced miR-143 Inhibits Propionibacterium acnes-Mediated Inflammatory Response in Skin other hsa-mir-155 "Carcinoma, Colon" 26744471 MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer. other hsa-mir-25 "Leukemia, Myeloid, Acute" 26744876 "Moreover, miR-155 level was positively associated with the white blood cell (WBC) count, serum lactate dehydrogenase (LDH) and C-reaction protein (CRP) value in peripheral blood (PB), as well as miR-25/miR-196b expression levels." other hsa-mir-34a Gastric Neoplasms 26745070 Our study demonstrates chrysin loaded PLGA-PEG promises a natural and efficient system for anticancer drug delivery to fight gastric cancer. other hsa-mir-892b Breast Neoplasms 26747895 miR-892b Silencing Activates NF-¦ÊB and Promotes Aggressiveness in Breast Cancer. other hsa-let-7b Melanoma 26754091 EGCG up-regulated miRNA-let-7b expression through 67LR in melanoma cells. other hsa-mir-142 Melanoma 26763444 "Identification, Review, and Systematic Cross-Validation of microRNA Prognostic Signatures in Metastatic Melanoma." other hsa-mir-146b Melanoma 26763444 "Identification, Review, and Systematic Cross-Validation of microRNA Prognostic Signatures in Metastatic Melanoma." other hsa-mir-150 Melanoma 26763444 "Identification, Review, and Systematic Cross-Validation of microRNA Prognostic Signatures in Metastatic Melanoma." other hsa-mir-155 Melanoma 26763444 "Identification, Review, and Systematic Cross-Validation of microRNA Prognostic Signatures in Metastatic Melanoma." other hsa-mir-342 Melanoma 26763444 "Identification, Review, and Systematic Cross-Validation of microRNA Prognostic Signatures in Metastatic Melanoma." other hsa-mir-106b "Carcinoma, Cervical" 26769181 Our data suggest that the TGF-¦Â1/miR-106b/DAB2 axis may be involved in the pathogenesis of cervical carcinoma. other hsa-mir-21 Breast Neoplasms 26769851 "miR-21, a well-documented oncogenic miRNA for promoting tumor cell metastasis, was also found to be involved in inhibitory activity of SSA in breast tumor cell motility through the modulation of TGFβ pathway." other hsa-mir-590 Diabetes Mellitus 26770982 "In this study, we identified a LDHA-suppressing microRNA (hsa-miR-590-3p)and used it together with human embryonic stem cell (hESC) derived pancreatic endoderm (PE) transplantation into a high-fat diet induced T2D mouse model. The procedure significantly improved glucose metabolism and other symptoms of T2D." other hsa-mir-155 Neoplasms [unspecific] 26771315 Screening of Pre-miRNA-155 Binding Peptides for Apoptosis Inducing Activity Using Peptide Microarrays. other hsa-mir-194 Aneurysm 26771601 "Aneurysm miRNA Signature Differs, Depending on Disease Localization and Morphology." other hsa-mir-19b-1 Aneurysm 26771601 "Aneurysm miRNA Signature Differs, Depending on Disease Localization and Morphology." other hsa-mir-21 Aneurysm 26771601 "Aneurysm miRNA Signature Differs, Depending on Disease Localization and Morphology." other hsa-mir-362 Aneurysm 26771601 "Aneurysm miRNA Signature Differs, Depending on Disease Localization and Morphology." other hsa-mir-550 Aneurysm 26771601 "Aneurysm miRNA Signature Differs, Depending on Disease Localization and Morphology." other hsa-mir-769 Aneurysm 26771601 "Aneurysm miRNA Signature Differs, Depending on Disease Localization and Morphology." other hsa-mir-18a Gastric Neoplasms 26772615 "Down regulation of miR-18a, miR-21 and miR-221 genes in gastric cancer cell line by chrysin-loaded PLGA-PEG nanoparticles." other hsa-mir-21 Gastric Neoplasms 26772615 "Down regulation of miR-18a, miR-21 and miR-221 genes in gastric cancer cell line by chrysin-loaded PLGA-PEG nanoparticles." other hsa-mir-221 Gastric Neoplasms 26772615 "Down regulation of miR-18a, miR-21 and miR-221 genes in gastric cancer cell line by chrysin-loaded PLGA-PEG nanoparticles." other hsa-mir-29b "Carcinoma, Lung, Non-Small-Cell" 26776158 knockdown of ETS1 led to upregulation of eight microRNAs and downregulation of miR-29b in the immune-evasion subtype. other hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 26780934 TP53 knockdown reduced the miRNA hsa-miR-145 other hsa-mir-34a "Squamous Cell Carcinoma, Esophageal" 26782413 Clinical significance of microRNA-34a in esophageal squamous cell carcinoma. other hsa-mir-29a Colorectal Carcinoma 26782449 Diagnostic performance of microRNA-29a for colorectal cancer: a meta-analysis. other hsa-mir-125b Ewing Sarcoma 26782555 Circulating miR-125b as a biomarker of Ewing's sarcoma in Chinese children. other hsa-let-7d Idiopathic Pulmonary Fibrosis 26787543 Lin28B causes epithelial-mesenchymal transition (EMT) by inhibition of let-7d. other hsa-mir-203 Breast Neoplasms 26790955 Kallistatin induces breast cancer cell apoptosis and autophagy by modulating Wnt signaling and microRNA synthesis. other hsa-mir-21 Breast Neoplasms 26790955 Kallistatin induces breast cancer cell apoptosis and autophagy by modulating Wnt signaling and microRNA synthesis. other hsa-mir-34a Breast Neoplasms 26790955 Kallistatin induces breast cancer cell apoptosis and autophagy by modulating Wnt signaling and microRNA synthesis. other hsa-mir-132 Alzheimer Disease 26792551 MicroRNA-132 and early growth response-1 in nucleus basalis of Meynert during the course of Alzheimer's disease. other hsa-mir-155 Breast Neoplasms 26795347 miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors. other hsa-mir-34c "Carcinoma, Nasopharyngeal" 26795575 Our study presents the current knowledge of miRNA regulatory network in NPC with combination of bioinformatics analysis and literature research. The hypothesis of miR-34c regulatory pathway may be beneficial in guiding further studies on the molecular mechanism of NPC tumorigenesis. other hsa-mir-221 "Squamous Cell Carcinoma, Oral" 26796268 depleting cells of miR-221 increases the sensitivity of the cells to Adriamycin. other hsa-mir-151a Hepatitis B Virus Infection 26801621 "We identified miR-24-3p, miR-151a-5p, and miR-425-5p as the most valid combination of reference genes for microRNA RT-qPCR studies in our hepatitis B virus replicating HepG2 cell model." other hsa-mir-24 Hepatitis B Virus Infection 26801621 "We identified miR-24-3p, miR-151a-5p, and miR-425-5p as the most valid combination of reference genes for microRNA RT-qPCR studies in our hepatitis B virus replicating HepG2 cell model." other hsa-mir-425 Hepatitis B Virus Infection 26801621 "We identified miR-24-3p, miR-151a-5p, and miR-425-5p as the most valid combination of reference genes for microRNA RT-qPCR studies in our hepatitis B virus replicating HepG2 cell model." other hsa-mir-17 "Carcinoma, Hepatocellular" 26804174 "SLU7 knockdown altered the splicing of the C13orf25 primary transcript, and markedly reduced the expression of its miR-17, miR-20 and miR-92a constituents." other hsa-mir-92a "Carcinoma, Hepatocellular" 26804174 "SLU7 knockdown altered the splicing of the C13orf25 primary transcript, and markedly reduced the expression of its miR-17, miR-20 and miR-92a constituents." other hsa-mir-132 Chronic Obstructive Pulmonary Disease 26807508 "Ectopic expression of PKR or miR-132 antagomiR alone failed to restore IFN-β induction, whereas cotreatment increased antiviral stress granule formation, induction of p300, and IFN-β in COPD pBECs." other hsa-mir-301a Prostate Neoplasms 26813459 "Taken together, we demonstrated that miR-301a/b-NDRG2 might be an important axis modulating autophagy and viability of prostate cancer cells under hypoxia." other hsa-mir-301b Prostate Neoplasms 26813459 "Taken together, we demonstrated that miR-301a/b-NDRG2 might be an important axis modulating autophagy and viability of prostate cancer cells under hypoxia." other hsa-mir-223 Pulmonary Hypertension 26815432 "Inhibition of miR-223 did not attenuate MCT PAH, whereas human prostacyclin synthase overexpression restored miRNA levels in MCT PAH to levels detected in naive rats. These data may establish a paradigm linking attenuation of PAH to restoration of BMPR2 signaling." other hsa-mir-205 "Carcinoma, Endometrial" 26817318 The role of miRNA in endometrial cancer in the context of miRNA 205 other hsa-mir-199 Ovarian Neoplasms 26819477 "miR-199a-5p and miR-34a-5p showed specific association with the disease, including molecular and cellular functions" other hsa-mir-34a Ovarian Neoplasms 26819477 "miR-199a-5p and miR-34a-5p showed specific association with the disease, including molecular and cellular functions" other hsa-mir-150 Sepsis 26822049 "Lower microRNA-150 may indicate a poor prognosis, and Picco monitoring combined with microRNA 150 detection may improve the prognostic efficiency in septic shock patients." other hsa-mir-224 Colorectal Carcinoma 26822534 Our research showed mechanistic links between miR-224 and Wnt/¦Â-catenin in the pathogenesis of CRC through modulation of GSK3¦Â and SFRP2. other hsa-mir-143 Colon Neoplasms 26824186 miR-143 or miR-145 overexpression increases cetuximab-mediated antibody-dependent cellular cytotoxicity in human colon cancer cells other hsa-mir-145 Colon Neoplasms 26824186 miR-143 or miR-145 overexpression increases cetuximab-mediated antibody-dependent cellular cytotoxicity in human colon cancer cells other hsa-mir-21 Diabetes Mellitus 26826461 Role of microRNA 21 in diabetes and associated/related diseases. other hsa-mir-101 Pancreatic Neoplasms 26828016 MicroRNA-101-3p reverses gemcitabine resistance by inhibition of ribonucleotide reductase M1 in pancreatic cancer. other hsa-mir-126 "Leukemia, Myeloid, Acute" 26832662 miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells. other hsa-mir-200c "Squamous Cell Carcinoma, Oral" 26839311 "suppression of the anti-inflammatory tumor suppressor microRNAs let-7d, miR-23b, and miR-200c was observed following PAR-2 stimulation." other hsa-mir-148a Prostate Neoplasms 26843836 "decreased expressions of tumor suppressors: miR-34a, miR-143, miR-148a and miR-200 family are involved in resistance of anti-cancer drugs" other hsa-mir-29a Myocardial Ischemic-Reperfusion Injury 26844226 "After Myocardial Ischemia-Reperfusion, miR-29a, and Let7 Could Affect Apoptosis through Regulating IGF-1." other hsa-mir-155 Liver Injury 26844784 Role of miR-155 in fluorooctane sulfonate-induced oxidative hepatic damage via the Nrf2-dependent pathway. other hsa-mir-133a Cardiomegaly 26845040 APN reversed miR-133a levels through AMPK activation other hsa-mir-145 Cardiovascular Diseases [unspecific] 26845891 THERAPEUTIC POTENTIAL OF MICRORNA IN THE FIELD OF CARDIOVASCULAR SURGERY. other hsa-mir-122 Hepatitis C Virus Infection 26845923 Mechanism of regulation of HCV replication by miR-122. other hsa-mir-216b "Carcinoma, Lung, Non-Small-Cell" 26852748 microRNA (miR)-216b levels were significantly downregulated in paclitaxel-treated NSCLC cells. other hsa-mir-145 Bladder Neoplasms 26852750 decreasing miR-145 expression reduced cisplatin sensitivity other hsa-mir-30d Heart Failure 26858295 "Letter by Sardu et al Regarding Article, Circulating MicroRNA-30d Is Associated With Response to Cardiac Resynchronization Therapy in Heart Failure and Regulates Cardiomyocyte Apoptosis: A Translational Pilot Study." other hsa-mir-30d Heart Failure 26858296 "Response to Letter Regarding Article, Circulating MicroRNA-30d Is Associated With Response to Cardiac Resynchronization Therapy in Heart Failure and Regulates Cardiomyocyte Apoptosis: A Translational Pilot Study." other hsa-mir-126 Leukemia 26859449 miR-126 Drives Quiescence and Self-Renewal in Leukemic Stem Cells. other hsa-mir-205 "Squamous Cell Carcinoma, Cerevial" 26864590 ΔNp63α attenuates tumor aggressiveness by suppressing miR-205/ZEB1-mediated epithelial-mesenchymal transition in cervical squamous cell carcinoma. other hsa-mir-92a "Leukemia, Myeloid" 26866730 The human myeloid leukemia cell line K562 secretes exosomes containing a large amount of miR-92a that enhances angiogenesis under normoxic and hypoxic conditions. other hsa-mir-182 Prostate Neoplasms 26870290 "mangiferin inhibited proliferation and induced apoptosis in PC3 human prostate cancer cells, and this effect was correlated with downregulation of Bcl-2 and upregulation of miR-182." other hsa-mir-31 Colorectal Carcinoma 26871294 "In conclusion, an inverse association was identified between EZH2 and miR-31 in colorectal cancers." other hsa-mir-26b Melanoma 26872428 MiR-26b inhibits melanoma cell proliferation and enhances apoptosis by suppressing TRAF5-mediated MAPK activation. other hsa-mir-144 Bronchiolitis Obliterans Syndrome 26874429 MicroRNA-144 is unlikely to play a role in bronchiolitis obliterans syndrome. other hsa-mir-375 "Carcinoma, Merkel Cell" 26877261 Roles for miR-375 in Neuroendocrine Differentiation and Tumor Suppression via Notch Pathway Suppression in Merkel Cell Carcinoma. other hsa-mir-193b "Carcinoma, Esophageal" 26878873 These results highlight the importance of miR-193b in determining oesophageal cancer cell viability and demonstrate an enhancement of chemotoxicity that is independent of apoptosis induction. other hsa-mir-200c "Squamous Cell Carcinoma, Oral" 26879838 Sulforaphane treatment resulted in a dose-dependent increase in the levels of tumor suppressive miR200c. other hsa-mir-141 "Carcinoma, Gastrooesophageal" 26885979 "The miRNA profile predictive for sensitivity to cisplatin,epirubicine and capecitabine was shown to be independently associated with OS and DSS in patients with gastrooesophageal cancer." other hsa-mir-200c "Carcinoma, Gastrooesophageal" 26885979 "The miRNA profile predictive for sensitivity to cisplatin,epirubicine and capecitabine was shown to be independently associated with OS and DSS in patients with gastrooesophageal cancer." other hsa-mir-505 "Carcinoma, Gastrooesophageal" 26885979 "The miRNA profile predictive for sensitivity to cisplatin,epirubicine and capecitabine was shown to be independently associated with OS and DSS in patients with gastrooesophageal cancer." other hsa-mir-99b "Carcinoma, Gastrooesophageal" 26885979 "The miRNA profile predictive for sensitivity to cisplatin,epirubicine and capecitabine was shown to be independently associated with OS and DSS in patients with gastrooesophageal cancer." other hsa-mir-196a-2 Breast Neoplasms 26886638 "The Associations of Single Nucleotide Polymorphisms in miR196a2, miR-499, and miR-608 With Breast Cancer Susceptibility: A STROBE-Compliant Observational Study." other hsa-mir-499 Breast Neoplasms 26886638 "The Associations of Single Nucleotide Polymorphisms in miR196a2, miR-499, and miR-608 With Breast Cancer Susceptibility: A STROBE-Compliant Observational Study." other hsa-mir-608 Breast Neoplasms 26886638 "The Associations of Single Nucleotide Polymorphisms in miR196a2, miR-499, and miR-608 With Breast Cancer Susceptibility: A STROBE-Compliant Observational Study." other hsa-mir-15a "Lymphoma, Burkitt" 26893685 Correlation between the overexpression of Yin Yang 1 and the expression levels of miRNAs other hsa-mir-134 Colorectal Carcinoma 26897940 Decreased Expression of MIR-134 and its Clinical Significance in Human Colorectal Cancer. other hsa-mir-23b Diabetic Nephropathy 26898629 Diabetic nephropathy: MiR-23b protects against fibrosis in diabetic nephropathy. other hsa-mir-155 "Adenocarcinoma, Lung" 26899325 Role of miR-155 in invasion and metastasis of lung adenocarcinoma A549 cells. other hsa-mir-328 Neurodegenerative Diseases [unspecific] 26900752 "These experiments reveal Dicer1-miR-328-Bace1 signalling as a determinant of BAT function, and highlight the potential of Bace1 inhibition as a therapeutic approach to improve not only neurodegenerative diseases" other hsa-mir-146a "Adenocarcinoma, Lung" 26902276 Effects of microRNA-146a on Fas-associated factor 2 and inflammatory factors in human lung adenocarcinoma A549 cells under the stimulation of cigarette smoke extract. other hsa-mir-200 Ovarian Neoplasms 26910180 The prognostic value of the miR-200 family in ovarian cancer: a meta-analysis. other hsa-mir-222 Melanoma 26912358 vesicles released by miR-222-overexpressing cells were able to transfer miR-222-dependent malignancy when taken-up by recipient primary melanomas. other hsa-mir-150 Stroke 26922365 "Upregulation of miR-150 expression could decrease vascular density of infarct border zone in rat after MCAO and decrease tube formation, proliferation, and migration of BMVECs." other hsa-mir-296 Neurofibromatosis type 2 26923924 Neurofibromatosis 2 (NF2) controls the invasiveness of glioblastoma through YAP-dependent expression of CYR61/CCN1 and miR-296-3p. other hsa-let-7a Breast Neoplasms 26924493 "Mir-206 and let-7 were up-regulated, and mir-21 expression was down-regulated in the exercise training compared to tumor group." other hsa-mir-21 Breast Neoplasms 26924493 "Mir-206 and let-7 were up-regulated, and mir-21 expression was down-regulated in the exercise training compared to tumor group." other hsa-mir-126 Breast Neoplasms 26926567 MALAT1 induced migration and invasion of human breast cancer cells by competitively binding miR-1 with cdc42. other hsa-mir-122 Hepatitis C Virus Infection 26927063 miR-125a-5p and miR-1231 have been shown to directly target hepatitis B virus (HBV) transcripts other hsa-mir-33 Alzheimer Disease 26936997 Understanding the Role of miR-33 in Brain Lipid Metabolism: Implications for Alzheimer's Disease. other hsa-mir-376 Breast Neoplasms 26940843 MIR376 as an important microRNA family for cancer formation and progression other hsa-mir-376 Glioma 26940843 MIR376 as an important microRNA family for cancer formation and progression other hsa-mir-376 Leukemia 26940843 MIR376 as an important microRNA family for cancer formation and progression other hsa-mir-376 Ovarian Neoplasms 26940843 MIR376 as an important microRNA family for cancer formation and progression other hsa-mir-21 Liver Cirrhosis 26946098 "increasing concentrations of Corilagin improved the quality of life, inhibited the mRNA expression of miR-21, promoted smad7 protein expression, and inhibited CTGF protein expression (p<0.05 or 0.01)." other hsa-mir-203 "Squamous Cell Carcinoma, Tongue" 26946357 miR-203 inhibits cell proliferation and promotes cisplatin induced cell death in tongue squamous cancer. other hsa-mir-370 "Diabetes Mellitus, Type 2" 26948318 salidroside can directly decrease the expression of miR-370 in type 2 diabetic mice other hsa-mir-155 Rheumatoid Arthritis 26950427 epigenetic regulators such as micro-RNAs (i.e. miR-155) are key regulators of myeloid cells activation in RA other hsa-mir-125b Inflammation 26954942 MiRNA-Mediated Macrophage Polarization and its Potential Role in the Regulation of Inflammatory Response. other hsa-mir-146a Inflammation 26956852 Effect of High MiR-146a Expression on the Inflammatory Reaction in BV2 Cells. other hsa-mir-221 Neoplasms [unspecific] 26959615 biological significance of miR-221/222 in a variety of malignancies indicates that they will play a crucial role in the future of innovative therapeutic strategies other hsa-mir-222 Neoplasms [unspecific] 26959615 biological significance of miR-221/222 in a variety of malignancies indicates that they will play a crucial role in the future of innovative therapeutic strategies other hsa-mir-375 Breast Neoplasms 26962366 Hsa-miR-375 is a predictor of local control in early stage breast cancer. other hsa-mir-223 Obesity 26962854 High-Density Lipoprotein-Associated miR-223 Is Altered after Diet-Induced Weight Loss in Overweight and Obese Males. other hsa-mir-24 Neoplasms [unspecific] 26967561 "melatonin can inhibit cell proliferation and migration, at least in part, by downregulating miR-24." other hsa-mir-211 Colorectal Carcinoma 26974151 Long Non-Coding RNA ucoo2kmd.1 Regulates CD44-Dependent Cell Growth by Competing for miR-211-3p in Colorectal Cancer. other hsa-mir-203 Prostate Neoplasms 26976978 increase of miR-203 expression after ZA exposure other hsa-mir-10a Ovarian Disease 26979400 AFSC-derived exosomes prevent ovarian follicular atresia in CTx-treated mice via the delivery of microRNAs in which both miR-146a and miR-10a are highly enriched and their potential target genes are critical to apoptosis. other hsa-mir-146a Pneumonia 26984146 "pneumococci recognition induces a negative feedback loop, preventing excessive inflammation via miR-146a and potentially other miRNAs." other hsa-mir-143 Neoplasms [unspecific] 26988859 The miR-143/miR-145 cluster and the tumor microenvironment: unexpected roles. other hsa-mir-145 Neoplasms [unspecific] 26988859 The miR-143/miR-145 cluster and the tumor microenvironment: unexpected roles. other hsa-mir-17 "Lymphoma, Follicular" 26997445 miR-31 and miR-17-5p levels change during transformation of follicular lymphoma. other hsa-mir-31 "Lymphoma, Follicular" 26997445 miR-31 and miR-17-5p levels change during transformation of follicular lymphoma. other hsa-mir-503 Neoplasms [unspecific] 26999740 miRNA-503 Promotes Tumor Progression and Is Associated with Early Recurrence and Poor Prognosis in Human Colorectal Cancer. other hsa-mir-29a "Carcinoma, Gastric" 27000664 Cell-derived microvesicles mediate the delivery of miR-29a/c to suppress angiogenesis in gastric carcinoma. other hsa-mir-29c "Carcinoma, Gastric" 27000664 Cell-derived microvesicles mediate the delivery of miR-29a/c to suppress angiogenesis in gastric carcinoma. other hsa-mir-20a Leukemia 27010069 "Mechanistic study further shows that induction of SIRPα protein in APL cells by ATO is mediated through suppression of c-Myc, resulting in reduction of three SIRPα-targeting microRNAs: miR-17, miR-20a and miR-106a." other hsa-mir-146 "Carcinoma, Thyroid, Papillary" 27011326 Family of microRNA-146 Regulates RAR¦Â in Papillary Thyroid Carcinoma. other hsa-mir-153 Breast Neoplasms 27012032 MicroRNA-153 Regulates NRF2 Expression and is Associated with Breast Carcinogenesis. other hsa-mir-186 "Leukemia, Myeloid, Acute" 27012040 Down-Regulation of miR-186 Correlates with Poor Survival in de novo Acute Myeloid Leukemia. other hsa-mir-30e Breast Neoplasms 27012041 Abnormal miRNA-30e Expression is Associated with Breast Cancer Progression. other hsa-mir-140 Chordoma 27016303 "This study uncovered the potential of miR-31, miR-140-3p, miR-148a, and miR-222-3p to be key molecules in the cell viability, cell cycle, and apoptosis in chordomas, as well as initiation,differentiation, and progression." other hsa-mir-148a Chordoma 27016303 "This study uncovered the potential of miR-31, miR-140-3p, miR-148a, and miR-222-3p to be key molecules in the cell viability, cell cycle, and apoptosis in chordomas, as well as initiation,differentiation, and progression." other hsa-mir-222 Chordoma 27016303 "This study uncovered the potential of miR-31, miR-140-3p, miR-148a, and miR-222-3p to be key molecules in the cell viability, cell cycle, and apoptosis in chordomas, as well as initiation,differentiation, and progression." other hsa-mir-210 "Carcinoma, Hepatocellular" 27018975 Down-regulation of TIMP2 by HIF-1α/miR-210/HIF-3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma. other hsa-mir-139 Neoplasms [unspecific] 27022656 The loss of MiR-139-5p promotes colitis-associated tumorigenesis by mediating PI3K/AKT/Wnt signaling. other hsa-mir-186 Alzheimer Disease 27029568 miR-186 in Alzheimer's disease: a big hope for a small RNA other hsa-mir-221 Breast Neoplasms 27031715 "5-aza treatment caused an increase of miRNA-10b, -122, -200b levels in MCF-7/S cells, miRNA-34a, -10b, -122, -200b and -320a levels in MCF-7/Dox cells and miRNA-34a, -10b, -200b and -320a levels in MCF-7/DDP cells." other hsa-mir-182 Keratitis 27035623 Inactivation of the miR-183/96/182 Cluster Decreases the Severity of Pseudomonas aeruginosa-Induced Keratitis. other hsa-mir-183 Keratitis 27035623 Inactivation of the miR-183/96/182 Cluster Decreases the Severity of Pseudomonas aeruginosa-Induced Keratitis. other hsa-mir-96 Keratitis 27035623 Inactivation of the miR-183/96/182 Cluster Decreases the Severity of Pseudomonas aeruginosa-Induced Keratitis. other hsa-mir-126 Dengue Virus Infection 27039024 "GRP75 is involved in processing of host miRNA, hsa-mir-126, that down regulates dengue virus replication." other hsa-mir-23b Neoplasms [unspecific] 27040799 Among down-regulators of PRODH/POX is an oncogenic transcription factor c-MYC and miR-23b*. other hsa-mir-200 Glioma 27041571 SHP-2 acts together with PI3K/AKT to regulate a ZEB1-miR-200 feedback loop in PDGFRα-driven gliomas. other hsa-mir-196a-2 Chronic Obstructive Pulmonary Disease 27043015 Association of MicroRNA-196a2 Variant with Response to Short-Acting ¦Â2-Agonist in COPD: An Egyptian Pilot Study. other hsa-mir-92a "Lymphoma, Burkitt" 27044389 "Our results describe for the first time miR-17, miR-19a, miR-19b, miR-20a, and miR-92a expression profiles in pBL." other hsa-mir-144 Bronchiolitis Obliterans Syndrome 27044533 MicroRNA-144 is unlikely to play a role in bronchiolitis obliterans syndrome. other hsa-mir-3646 Breast Neoplasms 27045586 MicroRNA-3646 Contributes to Docetaxel Resistance in Human Breast Cancer Cells by GSK-3¦Â/¦Â-Catenin Signaling Pathway. other hsa-mir-21 "Leukemia, Myelogenous, Chronic, BCR-ABL Positive" 27050372 Exosomes released by CML cells treated with Curcumin contain a high amount of miR-21 other hsa-mir-16 Colorectal Carcinoma 27055667 Prodigiosin caused a significant increase in miRNA-16-1 expression other hsa-mir-1 Myocardial Infarction 27056419 miR-1/133a control cardiac conductance and automaticity by regulating all phases of the cardiac action potential other hsa-mir-1 Vascular Hypertrophy 27056419 miR-1/133a control cardiac conductance and automaticity by regulating all phases of the cardiac action potential other hsa-mir-133a Vascular Hypertrophy 27056419 miR-1/133a control cardiac conductance and automaticity by regulating all phases of the cardiac action potential. other hsa-mir-208 Vascular Hypertrophy 27056419 miR-208/499 located in introns of the heavy chain myosin genes regulate expression of sarcomeric contractile proteins. other hsa-mir-499 Myocardial Infarction 27056419 miR-208/499 located in introns of the heavy chain myosin genes regulate expression of sarcomeric contractile proteins. other hsa-mir-17 "Leukemia, Lymphocytic, Chronic, B-Cell" 27059597 "Interestingly, TLR1/2 triggering restored BCR functionality, likely breaching the anergic state, and this was accompanied by induction of the miR-17âˆ?2 cluster" other hsa-mir-155 Pancreatic Neoplasms 27060060 "A vast number of miRNAs, including the well-studied miR-21, miR-155 and miR-34, has been shown to regulate PDAC growth, invasion and metastasis" other hsa-mir-21 Pancreatic Neoplasms 27060060 "A vast number of miRNAs, including the well-studied miR-21, miR-155 and miR-34, has been shown to regulate PDAC growth, invasion and metastasis" other hsa-mir-34 Pancreatic Neoplasms 27060060 "A vast number of miRNAs, including the well-studied miR-21, miR-155 and miR-34, has been shown to regulate PDAC growth, invasion and metastasis" other hsa-mir-126 "Colitis, Ulcerative" 27061150 mango polyphenols attenuated inflammatory response by modulating the PI3K/AKT/mTOR pathway at least in part through upregulation of miRNA-126 expression both in vitro and in vivo other hsa-let-7a Melanoma 27063098 two other miRNA modulators of EMT (miR-191 and let-7a) in serum exosomes other hsa-let-7i Melanoma 27063098 two other miRNA modulators of EMT (miR-191 and let-7a) in serum exosomes other hsa-mir-191 Melanoma 27063098 two other miRNA modulators of EMT (miR-191 and let-7a) in serum exosomes other hsa-mir-146a Oral Lichen Planus 27063128 "Detection of miR-155, miR-146a in PBNCs and tissues from patients with oral lichen planus." other hsa-mir-155 Oral Lichen Planus 27063128 "Detection of miR-155, miR-146a in PBNCs and tissues from patients with oral lichen planus." other hsa-mir-663 Graft-Versus-Host Disease 27063175 Role of miR-663 in acute renal graft rejection: an in vitro study. other hsa-mir-126 Thyroid Neoplasms 27067785 Interactive role of miR-126 on VEGF-A and progression of papillary and undifferentiated thyroid carcinoma. other hsa-mir-182 "Carcinoma, Lung, Non-Small-Cell" 27073334 MiR-1244 sensitizes the resistance of non-small cell lung cancer A549 cell to cisplatin other hsa-mir-21 Recurrent Wheezing 27075111 Extracellular microRNA-21 and microRNA-26a increase in body fluids from rats with antigen induced pulmonary inflammation and children with recurrent wheezing. other hsa-mir-26a Recurrent Wheezing 27075111 Extracellular microRNA-21 and microRNA-26a increase in body fluids from rats with antigen induced pulmonary inflammation and children with recurrent wheezing. other hsa-mir-155 "Adenocarcinoma, Lung" 27081085 "We identified a regulatory network including miR-15b and miR-155, and transcription factors with prognostic value in lung cancer." other hsa-mir-31 Colorectal Carcinoma 27082577 MicroRNA Expression Signatures Associated With BRAF-Mutated Versus KRAS-Mutated Colorectal Cancers. other hsa-mir-362 Colorectal Carcinoma 27082577 MicroRNA Expression Signatures Associated With BRAF-Mutated Versus KRAS-Mutated Colorectal Cancers. other hsa-mir-425 Colorectal Carcinoma 27082577 MicroRNA Expression Signatures Associated With BRAF-Mutated Versus KRAS-Mutated Colorectal Cancers. other hsa-mir-877 Colorectal Carcinoma 27082577 MicroRNA Expression Signatures Associated With BRAF-Mutated Versus KRAS-Mutated Colorectal Cancers. other hsa-let-7c Neoplasms [unspecific] 27087117 microRNA let-7c (let-7c) contributed to the anisomycin-induced apoptosis other hsa-mir-191 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 27093985 Expression of microRNA-191 in T lymphoblastic leukemia/lymphoma and its underlying mechanism. other hsa-mir-200c Neoplasms [unspecific] 27094812 "miR-200c, an illustrious tumor suppressor, is one of the highly studied miRNAs in terms of development, stemness, proliferation, epithelial-mesenchymal transition (EMT), therapy resistance, and metastasis." other hsa-let-7 Neoplasms [unspecific] 27097729 The insights of Let-7 miRNAs in oncogenesis and stem cell potency. other hsa-mir-206 Myocardial Infarction 27103465 "In an acute model of myocardial infarction, transplanted hypoxic MSCs showed a significantly improved survival as compared with hypoxic MSCs overexpressing miR-206." other hsa-mir-21 Atherosclerosis 27107761 "LaCM decreased apoptosis, necrosis and inflammatory miR-155 and conversely increased anti-apoptotic miR-21 in Ec-LPS-treated HUVECs." other hsa-mir-21 Liver Diseases [unspecific] 27107786 "In L-02 cells exposed to arsenite, microRNA-21 (miRNA-21) is over-expressed" other hsa-mir-200b Retinal Degeneration 27113191 Effect of MiR-200b on retinal endothelial cell function in high-glucose condition and the mechanism. other hsa-mir-221 Asthma 27113449 The degranulation was found to be significantly increased in miR-221 overexpressed cells while it was found to be significantly decreased in miR-221 downregulated cells. other hsa-let-7a Liver Cirrhosis 27115285 There was decreased expression of let-7a in BDL and Mdr2(-/-) cholangiocytes that was associated with increased NGF expression. other hsa-mir-124 Neurodegenerative Diseases [unspecific] 27117821 MicroRNAs underlying memory deficits in neurodegenerative disorders. other hsa-mir-132 Neurodegenerative Diseases [unspecific] 27117821 MicroRNAs underlying memory deficits in neurodegenerative disorders. other hsa-mir-34 Neurodegenerative Diseases [unspecific] 27117821 MicroRNAs underlying memory deficits in neurodegenerative disorders. other hsa-mir-363 "Leukemia, Lymphocytic, Chronic, B-Cell" 27118451 Our results reveal an enrichment of specific cellular miRNAs including miR-363 within EVs derived from CD40/IL-4-stimulated CLL cells compared with parental cell miRNA content and control EVs from unstimulated CLL cells. other hsa-mir-21 Acute Kidney Failure 27122240 "In summary, we report noninvasive detection of AKI in humans by combining the sensitivity of KIM-1 along with mechanistic potentials of miR-21, -200c, and -423." other hsa-mir-200c "Carcinoma, Renal Cell, Clear-Cell" 27123083 "Aza-induced upregulation of miR-200c may inhibit migration, invasion and EMT in ccRCC cells." other hsa-mir-17 Leukemia 27123834 Combinatorial treatment against miR-17-5p and miR-19a-3p of the miR-17-92 cluster dramatically reduces colony forming ability of MLL-fusion containing cell lines relative to non-MLL acute myeloid leukemia (AML) controls. other hsa-mir-124 Stroke 27126323 lithium increased miR-124 expression other hsa-mir-20a Multiple Myeloma 27129167 "Moreover, nano-sized exosomes were isolated with significantly increasing internal RNAs and down-regulation of exosomal miR-16-5p, miR-15a-5p and miR-20a-5p, miR-17-5p was revealed in the patients resistant to Bz." other hsa-mir-425 Cardiovascular Diseases [unspecific] 27132035 "After NaAsO2 treatment, we found the expression of microRNA-425-5p (miR-425-5p) was reduced in vitro and in vivo" other hsa-mir-425 Hypertension 27132035 "After NaAsO2 treatment, we found the expression of microRNA-425-5p (miR-425-5p) was reduced in vitro and in vivo" other hsa-mir-425 Peripheral Vascular Disease 27132035 "After NaAsO2 treatment, we found the expression of microRNA-425-5p (miR-425-5p) was reduced in vitro and in vivo" other hsa-mir-103 Diabetes Mellitus 27137869 Long-term treatment with 500 μM CML during adipogenesis resulted in increases in miR-103 and miR-143 levels other hsa-mir-143 Diabetes Mellitus 27137869 Long-term treatment with 500 μM CML during adipogenesis resulted in increases in miR-103 and miR-143 levels other hsa-mir-203 Gastric Neoplasms 27142767 Berberine modulates cisplatin sensitivity of human gastric cancer cells by upregulation of miR-203. other hsa-mir-107 Alzheimer Disease 27143098 osthole plays a neuroprotective activity role in part through up-regulate miR-107 in AD. other hsa-mir-34a "Leukemia, Lymphoblastic, Acute" 27150988 Expression of miR-34a in Bone Marrow of Adult Acute Lymphoblastic Leukemia and Its Significance in Cell Drug Resistance. other hsa-mir-34c Bone Disease [unspecific] 27156573 Vaspin regulates the osteogenic differentiation of MC3T3-E1 through the PI3K-Akt/miR-34c loop. other hsa-mir-16 Gastric Neoplasms 27157613 MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1. other hsa-mir-21 Vascular Hypertrophy 27160852 Celastrol also inhibited the miR-21/ERK signalling pathway. other hsa-mir-181a "Carcinoma, Thyroid, Papillary" 27164936 MiRNA-21 and MiRNA-181a-5p were found to be expressed reciprocally in the exosomes of patients with papillary and follicular TC other hsa-mir-21 "Carcinoma, Thyroid, Papillary" 27164936 MiRNA-21 and MiRNA-181a-5p were found to be expressed reciprocally in the exosomes of patients with papillary and follicular TC other hsa-mir-140 Arthritis 27165343 estrogen acts via ER and miR-140 to inhibit the catabolic activity of proteases within the chondrocyte extracellular matrix. other hsa-mir-140 Osteoarthritis 27165343 estrogen acts via ER and miR-140 to inhibit the catabolic activity of proteases within the chondrocyte extracellular matrix. other hsa-mir-489 Breast Neoplasms 27171498 miR-489 could reverse the chemoresistance of breast cancer via the PI3K-Akt pathway by targeting SPIN1. other hsa-mir-139 Colorectal Carcinoma 27173050 miR-139-5p sensitizes colorectal cancer cells to 5-fluorouracil by targeting NOTCH-1. other hsa-mir-451 Gastric Neoplasms 27173190 "Propofol effectively inhibited proliferation and induced apoptosis in gastric cancer cells, which was partly owing to the downregulation of MMP-2 expression by miR-451." other hsa-mir-155 Colorectal Carcinoma 27176480 S100A8 activated the NF-κB pathway in the macrophages and promoted the expression of miR-155 other hsa-mir-126 Heart Failure 27180261 miR-126 up-regulation activates EPCs and ECs and contributes to vascular healing and neovessel formation. other hsa-mir-126 Myocardial Infarction 27180261 miR-126 up-regulation activates EPCs and ECs and contributes to vascular healing and neovessel formation. other hsa-mir-494 Muscle Diseases [unspecific] 27181718 Effects of microRNA-494 on the fiber type-specific skeletal myogenesis in human induced pluripotent stem cells. other hsa-mir-145 Vascular Disease [unspecific] 27186305 MicroRNA-145 regulates platelet-derived growth factor-induced human aortic vascular smooth muscle cell proliferation and migration by targeting CD40 other hsa-mir-200 "Carcinoma, Lung" 27189341 AKT2 can regulate miR-200a in a histology- or stage-specific manner other hsa-mir-200a "Carcinoma, Lung" 27189341 AKT2 can regulate miR-200a in a histology- or stage-specific manner and that other hsa-mir-122 "Carcinoma, Hepatocellular" 27194671 High expression levels of plasma miR-122 are associated with early TACE refractoriness in HCC patients treated with TACE. other hsa-mir-29b "Carcinoma, Lung, Non-Small-Cell" 27199349 "Overall, our results reveal a complexity in cancer for miR-29b, which can act as either an oncogene or tumor suppressor gene depending on signaling context." other hsa-mir-4505 Oral Neoplasms 27207653 a microRNA (miR) analysis revealed that LCN2 can suppress CAIX expression and cell migration through miR-4505 induction. other hsa-mir-92a Cardiovascular Diseases [unspecific] 27208561 PDW/miR-92a-score with a specificity of 97.5% and a sensitivity of 80.0% in relation to detect aspirin resistance. other hsa-mir-497 Cerebral Ischemia 27209189 "amikacin inhibits miR-497 maturation and promotes ischemic neuronal survival by upregulating anti-apoptotic protein, bcl-2." other hsa-mir-494 Breast Neoplasms 27216190 Elevating Dicer expression increased levels of the AXL kinase targeting miRNA miR-494 other hsa-mir-126 Diabetic Retinopathy 27225425 MicroRNA-126 (miR-126) plays a potential role in the pathogenesis in DR other hsa-mir-203 Colorectal Carcinoma 27236538 overexpression of miR-203 sensitizes colon cancer cells other hsa-mir-20a Glioma 27242439 The expression levels of miR-20a decreased significantly after U-87 and U-251 cells were treated with EMAP-II. other hsa-mir-92a Liver Cirrhosis 27246196 miR-92a expression closely correlated with the frequency of a subset of IL-17-producing T helper cells (Th17) other hsa-mir-181a Ovarian Neoplasms 27249598 miR-181a overexpression decreased the PTX sensitivity of SKOV3 cells and while miR-181a inhibition increased the sensitivity of SKOV3/PTX cells. other hsa-mir-449a Prostate Neoplasms 27250340 Overexpression of miR-449a or knockdown of c-Myc promoted the sensitivity of LNCaP cells to IR. other hsa-mir-27b Chondrosarcoma 27252405 Adiponectin promotes VEGF-C-dependent lymphangiogenesis by inhibiting miR-27b through a CaMKII/AMPK/p38 signaling pathway in human chondrosarcoma cells other hsa-mir-146a Inflammation 27256622 These effects were partially mediated through RvD2 induction of microRNA-146a other hsa-mir-200 Breast Neoplasms 27257068 "miR-200 levels increase following hPMR1 knockdown, and changes in miR-200 family microRNAs were matched by corresponding changes in miR-200 targets and reporter expression." other hsa-mir-30e Schizophrenia 27258654 miRNA-30e is associated with cognitive impairment in schizophrenia and depression. other hsa-mir-30 "Adenocarcinoma, Colon" 27261459 miR-30 family likely plays an important role in IEC homeostasis other hsa-mir-182 "Carcinoma, Hepatocellular" 27262453 "Upon forcing miR-182 expression in the HCC NK-cells, upregulation of both receptors was observed." other hsa-mir-152 "Carcinoma, Endometrial" 27263284 Effect of Progesterone-induced MicroRNA-152 on the Proliferation of Endometrial Epithelial Cells. other hsa-mir-4496 Gastric Neoplasms 27265143 "Here, we show that rebamipide suppresses H. pylori CagA-induced β-catenin and its target cancer-initiating cells (C-IC) marker gene expression via upregulation of miRNA-320a and -4496." other hsa-mir-379 "Carcinoma, Hepatocellular" 27266355 "Effects of microRNA-379-5p on proliferation, migration and invasion of hepatocellular carcinoma cell line." other hsa-mir-21 Lung Neoplasms 27266356 The effect and mechanism of microRNA-21 on cis-dichlorodiamineplatinum resistance in lung cancer cell strain. other hsa-mir-34a Glioma 27268916 miR-34a was downregulated under hypoxia but upregulated by resveratrol other hsa-mir-21 Autoimmune Diseases [unspecific] 27271606 miR-21 was found to be correlated with the pathogenesis of autoimmune diseases other hsa-mir-146b Prostate Neoplasms 27273955 MicroRNA-146b acts as a potential tumor suppressor in human prostate cancer. other hsa-mir-141 Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-16 Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-23c Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-3176 Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-32 Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-3654 Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-3673 Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-381 Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-3915 Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-429 Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-488 Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-5004 Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-606 Prostate Neoplasms 27278879 "hub hsa-miR3176, -141-3p, -5004-5p, -16-5p, -3915, -488â€?p, -23c, -3673 and -3654 were potential targets to hub gene androgen receptor (AR) and phosphatase and tensin homolog (PTEN)." other hsa-mir-206 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 27279635 co-transfection of miR-375 and miR-206 exhibited a less effective inhibitory effect other hsa-mir-221 Intrahepatic Cholangiocarcinoma 27280413 no correlation was found between the expression levels of these molecular markers and histopathological differentiation grade. other hsa-mir-15a "Leukemia, Lymphoblastic, Acute" 27281445 Prednisolone in concentration of 700 ?M was significantly increased the expression of miR 16-1 and miR 15a after 24 h and 48 h treatment other hsa-mir-16 "Leukemia, Lymphoblastic, Acute" 27281445 Prednisolone in concentration of 700 ?M was significantly increased the expression of miR 16-1 and miR 15a after 24 h and 48 h treatment other hsa-mir-1 Neoplasms [unspecific] 27286699 miR-1 is classified to be a tumor suppressor other hsa-mir-21 Heart Failure 27292200 heart failure (miR-21 and miR-133a) other hsa-mir-146a Infection [unspecific] 27297392 miR-146a was found to be differentially regulated in THP-1 cells between probiotic and pathogenic bacteria. other hsa-mir-410 Blindness 27297412 antisense microRNA-410 (anti-miR-410) induces RPE differentiation from amniotic epithelial stem cells. other hsa-let-7d Lymphoma 27300436 "ΔNp63 inhibition decreases the levels of its transcriptional target, DGCR8, and the maturation of let-7d and miR-128" other hsa-mir-128 Lymphoma 27300436 "ΔNp63 inhibition decreases the levels of its transcriptional target, DGCR8, and the maturation of let-7d and miR-128" other hsa-mir-30a Breast Neoplasms 27302063 regulation of lumen formation by miR-342 other hsa-mir-122 Hepatitis C Virus Infection 27303683 HCV infection requires miR-122 other hsa-mir-125b Prostate Neoplasms 27305142 MiRNAs were shown to be differently distributed between different fractions of extracellular vesicles. other hsa-mir-16 Prostate Neoplasms 27305142 MiRNAs were shown to be differently distributed between different fractions of extracellular vesicles. other hsa-mir-19b Prostate Neoplasms 27305142 MiRNAs were shown to be differently distributed between different fractions of extracellular vesicles. other hsa-mir-205 Prostate Neoplasms 27305142 MiRNAs were shown to be differently distributed between different fractions of extracellular vesicles. other hsa-mir-25 Prostate Neoplasms 27305142 MiRNAs were shown to be differently distributed between different fractions of extracellular vesicles. other hsa-let-7 "Carcinoma, Thyroid, Papillary" 27314338 "let-7 miRNA was found to reduce RAS levels, acting as a tumor suppressor gene." other hsa-mir-125b Neoplasms [unspecific] 27321180 Forced expression of hsa-miR-125b in these cells resulted in radiosensitivity other hsa-mir-128 Breast Neoplasms 27322220 miR-128 in exosomes negatively regulates the level of Bax in MCF-7 recipient cells and inhibits cell proliferation. other hsa-mir-29b Bladder Neoplasms 27322434 miR-21 and miR-29b depression have been shown in Snail-1 suppressed group in EJ-138 cells in vitro. other hsa-mir-27b Chondrosarcoma 27345723 expression of microRNA-27b was negatively regulated by leptin other hsa-mir-21 Colorectal Carcinoma 27349026 Plasma Expression Levels of Circulating miR-21 are not Useful for Diagnosing and Monitoring Colorectal Cancer. other hsa-mir-1 Gastric Neoplasms 27349337 "miR-1, -133 and -206 family in GC" other hsa-mir-133 Gastric Neoplasms 27349337 "miR-1, -133 and -206 family in GC" other hsa-mir-206 Gastric Neoplasms 27349337 "miR-1, -133 and -206 family in GC" other hsa-mir-1 Ovarian Neoplasms 27354590 loss of growth-inhibitory functionality of miR-1 other hsa-mir-141 Kidney Neoplasms 27358122 Invasion and metastasis ability of renal cancer cell strains 786-0: under the influence of miR-141. other hsa-mir-210 Cardiovascular Diseases [unspecific] 27359286 "miR-210 has also been shown to be associated with the development of different human diseases including various types of cancers, cardiovascular and cerebrovascular diseases, and immunological diseases." other hsa-mir-122 Hepatitis C Virus Infection 27366906 Hepatitis C Virus Core Protein Promotes miR-122 Destabilization by Inhibiting GLD-2. other hsa-mir-21 Squamous Cell Carcinoma 27371785 Blueberry also modulated the expression of the oncomiR miR-21 and the tumor suppressor let-7. other hsa-mir-21 Breast Neoplasms 27372573 "MCF-7 has a high level of miR-21, miR-375, and miR-27a as target miRNAs." other hsa-mir-27a Breast Neoplasms 27372573 "MCF-7 has a high level of miR-21, miR-375, and miR-27a as target miRNAs." other hsa-mir-375 Breast Neoplasms 27372573 "MCF-7 has a high level of miR-21, miR-375, and miR-27a as target miRNAs." other hsa-mir-132 Neuroblastoma 27374124 New perspectives for multi-level regulations of neuronal acetylcholinesterase by dioxins. other hsa-mir-212 Neuroblastoma 27374124 New perspectives for multi-level regulations of neuronal acetylcholinesterase by dioxins. other hsa-mir-25 Neuroblastoma 27374124 New perspectives for multi-level regulations of neuronal acetylcholinesterase by dioxins. other hsa-mir-132 Inflammation 27378528 LPS down-regulated the expression of miRNA-132. other hsa-mir-34a Alzheimer Disease 27378912 Over-Expressed Pathogenic miRNAs in Alzheimer's Disease (AD) and Prion Disease (PrD) Drive Deficits in TREM2-Mediated A¦Â42 Peptide Clearance. other hsa-let-7 Neuroblastoma 27383785 Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma. other hsa-mir-19 Schizophrenia 27387650 Our study demonstrates the significance of posttranscriptional gene regulation by miR-19 in preventing the irregular migration of adult-born neurons that may contribute to the etiology of schizophrenia. other hsa-mir-125b Wound Healing 27388239 "the uMSC-exosomal microRNAs were examined by high-throughput sequencing, with a group of specific microRNAs (miR-21, miR-23a, miR-125b, and miR-145) found to play key roles in suppressing myofibroblast formation by inhibiting excess α-smooth muscle actin and collagen deposition associated with activity of the transforming growth factor-β/SMAD2 signaling pathway." other hsa-mir-145 Wound Healing 27388239 "the uMSC-exosomal microRNAs were examined by high-throughput sequencing, with a group of specific microRNAs (miR-21, miR-23a, miR-125b, and miR-145) found to play key roles in suppressing myofibroblast formation by inhibiting excess α-smooth muscle actin and collagen deposition associated with activity of the transforming growth factor-β/SMAD2 signaling pathway." other hsa-mir-21 Wound Healing 27388239 "the uMSC-exosomal microRNAs were examined by high-throughput sequencing, with a group of specific microRNAs (miR-21, miR-23a, miR-125b, and miR-145) found to play key roles in suppressing myofibroblast formation by inhibiting excess α-smooth muscle actin and collagen deposition associated with activity of the transforming growth factor-β/SMAD2 signaling pathway." other hsa-mir-23a Wound Healing 27388239 "the uMSC-exosomal microRNAs were examined by high-throughput sequencing, with a group of specific microRNAs (miR-21, miR-23a, miR-125b, and miR-145) found to play key roles in suppressing myofibroblast formation by inhibiting excess α-smooth muscle actin and collagen deposition associated with activity of the transforming growth factor-β/SMAD2 signaling pathway." other hsa-mir-18a Wound Healing 27390086 "We found miR-18a was most susceptible to SH treatment, the target prediction of which were enriched in a bunch of pathways implicated in corneal wound healing." other hsa-mir-122 "Carcinoma, Hepatocellular" 27391076 "we showed that the isomiR profiles of liver specific MiR122, and a few other miRNAs, correlated with MC-LR treatment." other hsa-mir-122 Liver Cirrhosis 27391076 "we showed that the isomiR profiles of liver specific MiR122, and a few other miRNAs, correlated with MC-LR treatment." other hsa-mir-122 Liver Diseases [unspecific] 27391076 "we showed that the isomiR profiles of liver specific MiR122, and a few other miRNAs, correlated with MC-LR treatment." other hsa-mir-95 Colorectal Carcinoma 27393650 "In conclusion, calycosin exerts an inhibitory effect on proliferation of CRC cells in vivo and in vitro, through ERβ-mediated regulation of the IGF-1R, PI3K/Akt signaling pathways and of miR-95 expression." other hsa-mir-9 Alzheimer Disease 27394443 These results demonstrated that osthole plays a neuroprotective activity role in part through upregulating miR-9 in AD. other hsa-mir-17 Neuroblastoma 27396325 "Here, we demonstrate that this microRNA (miRNA) cluster selectively targets several members of the nuclear hormone receptor (NHR) superfamily, and we present a unique NHR signature associated with the survival of neuroblastoma patients." other hsa-mir-518a Atrioventricular Septal Defect 27396555 "Furthermore, miRNA-DEG regulatory networks were constructed. IL1B was the hub-gene of PPI networks, and AUTS2 and KIAA2022 were predicted to be targeted by miR-518a, miR518e, miR-518f, miR-528a, and miR-96.IL1B, IL12RB2, AUTS2, and KIAA2022 might participate in AVSD in DS patients, and AUTS2 and KIAA2022 might be targeted by miR-518a, miR-518e, miR-518f, miR-528a, and miR-96." other hsa-mir-518e Atrioventricular Septal Defect 27396555 "Furthermore, miRNA-DEG regulatory networks were constructed. IL1B was the hub-gene of PPI networks, and AUTS2 and KIAA2022 were predicted to be targeted by miR-518a, miR518e, miR-518f, miR-528a, and miR-96.IL1B, IL12RB2, AUTS2, and KIAA2022 might participate in AVSD in DS patients, and AUTS2 and KIAA2022 might be targeted by miR-518a, miR-518e, miR-518f, miR-528a, and miR-96." other hsa-mir-518f Atrioventricular Septal Defect 27396555 "Furthermore, miRNA-DEG regulatory networks were constructed. IL1B was the hub-gene of PPI networks, and AUTS2 and KIAA2022 were predicted to be targeted by miR-518a, miR518e, miR-518f, miR-528a, and miR-96.IL1B, IL12RB2, AUTS2, and KIAA2022 might participate in AVSD in DS patients, and AUTS2 and KIAA2022 might be targeted by miR-518a, miR-518e, miR-518f, miR-528a, and miR-96." other hsa-mir-528a Atrioventricular Septal Defect 27396555 "Furthermore, miRNA-DEG regulatory networks were constructed. IL1B was the hub-gene of PPI networks, and AUTS2 and KIAA2022 were predicted to be targeted by miR-518a, miR518e, miR-518f, miR-528a, and miR-96.IL1B, IL12RB2, AUTS2, and KIAA2022 might participate in AVSD in DS patients, and AUTS2 and KIAA2022 might be targeted by miR-518a, miR-518e, miR-518f, miR-528a, and miR-96." other hsa-mir-96 Atrioventricular Septal Defect 27396555 "Furthermore, miRNA-DEG regulatory networks were constructed. IL1B was the hub-gene of PPI networks, and AUTS2 and KIAA2022 were predicted to be targeted by miR-518a, miR518e, miR-518f, miR-528a, and miR-96.IL1B, IL12RB2, AUTS2, and KIAA2022 might participate in AVSD in DS patients, and AUTS2 and KIAA2022 might be targeted by miR-518a, miR-518e, miR-518f, miR-528a, and miR-96." other hsa-mir-200a "Carcinoma, Lung, Non-Small-Cell" 27396618 we show that down-regulating Zeb-1 by inducing miR-200a or β-Catenin siRNA can increase drug sensitivity of TKI-resistant cells. other hsa-mir-494 Retinoblastoma 27399693 "The overexpression of miR-494-3p in SAS cells increased the population of senescence-associated β-galactosidase positive cells, the expression of p16(INK4a) and retinoblastoma 1 (RB1), as well as downregulated Bmi1." other hsa-mir-494 "Squamous Cell Carcinoma, Oral" 27399693 "The overexpression of miR-494-3p in SAS cells increased the population of senescence-associated β-galactosidase positive cells, the expression of p16(INK4a) and retinoblastoma 1 (RB1), as well as downregulated Bmi1." other hsa-mir-17 Pancreatic Neoplasms 27400681 "Mechanically, we discovered that high GFRα2 expression level leads to PTEN inactivation via enhancing Mir-17-5p level." other hsa-mir-9 Osteoarthritis 27404795 IL-6 expression is achieved through increased recruitment of CEBPα to the MCPIP1 promoter and by relieving the miR-9-mediated inhibition of MCPIP1 expression in OA chondrocytes. other hsa-mir-31 Psoriasis 27405090 Its own regulation is disrupted during the onset and progression of cancer and autoimmune disorders such as psoriasis and systemic lupus erythematosus. other hsa-mir-31 Systemic Lupus Erythematosus 27405090 Its own regulation is disrupted during the onset and progression of cancer and autoimmune disorders such as psoriasis and systemic lupus erythematosus. other hsa-mir-155 Ankylosing Spondylitis 27412942 Conclusion XFC could effectively improve hypercoagulative state in active AS patients. The potential mechanism may be associated with the inhibition of miR-155 and NF-κB signal pathway. other hsa-let-7a "Carcinoma, Ovarian" 27419385 Identification of stably expressed reference small non-coding RNAs for microRNA quantification in high-grade serous ovarian carcinoma tissues. other hsa-mir-103a "Carcinoma, Ovarian" 27419385 Identification of stably expressed reference small non-coding RNAs for microRNA quantification in high-grade serous ovarian carcinoma tissues. other hsa-mir-16 "Carcinoma, Ovarian" 27419385 Identification of stably expressed reference small non-coding RNAs for microRNA quantification in high-grade serous ovarian carcinoma tissues. other hsa-mir-191 "Carcinoma, Ovarian" 27419385 Identification of stably expressed reference small non-coding RNAs for microRNA quantification in high-grade serous ovarian carcinoma tissues. other hsa-mir-423 "Carcinoma, Ovarian" 27419385 Identification of stably expressed reference small non-coding RNAs for microRNA quantification in high-grade serous ovarian carcinoma tissues. other hsa-mir-92a "Carcinoma, Ovarian" 27419385 Identification of stably expressed reference small non-coding RNAs for microRNA quantification in high-grade serous ovarian carcinoma tissues. other hsa-mir-221 Breast Neoplasms 27420990 "The expression of miR-221/222 in the serum of the patients with post-menopausal breast cancer was higher than that of T2DM patients (P < 0.05), but lower than that of the T2DM patients who were also positive for post-menopausal breast cancer (P < 0.05);" other hsa-mir-221 "Diabetes Mellitus, Type 2" 27420990 "The expression of miR-221/222 in the serum of the patients with post-menopausal breast cancer was higher than that of T2DM patients (P < 0.05), but lower than that of the T2DM patients who were also positive for post-menopausal breast cancer (P < 0.05)" other hsa-mir-222 Breast Neoplasms 27420990 "The expression of miR-221/222 in the serum of the patients with post-menopausal breast cancer was higher than that of T2DM patients (P < 0.05), but lower than that of the T2DM patients who were also positive for post-menopausal breast cancer (P < 0.05)" other hsa-mir-222 "Diabetes Mellitus, Type 2" 27420990 "The expression of miR-221/222 in the serum of the patients with post-menopausal breast cancer was higher than that of T2DM patients (P < 0.05), but lower than that of the T2DM patients who were also positive for post-menopausal breast cancer (P < 0.05)" other hsa-mir-130a "Leukemia, Myeloid, Chronic" 27421670 "Here, the L-amino acid oxidase from Calloselasma rhodostoma (CR-LAAO) venom altered the apoptotic machinery regulation by modulating the expression of the miR-145, miR-26a, miR-142-3p, miR-21, miR-130a, and miR-146a, and of the apoptosis-related proteins Bid, Bim, Bcl-2, Ciap-2, c-Flip, and Mcl-1 in Bcr-Abl(+) cells." other hsa-mir-142 "Leukemia, Myeloid, Chronic" 27421670 "Here, the L-amino acid oxidase from Calloselasma rhodostoma (CR-LAAO) venom altered the apoptotic machinery regulation by modulating the expression of the miR-145, miR-26a, miR-142-3p, miR-21, miR-130a, and miR-146a, and of the apoptosis-related proteins Bid, Bim, Bcl-2, Ciap-2, c-Flip, and Mcl-1 in Bcr-Abl(+) cells." other hsa-mir-145 "Leukemia, Myeloid, Chronic" 27421670 "Here, the L-amino acid oxidase from Calloselasma rhodostoma (CR-LAAO) venom altered the apoptotic machinery regulation by modulating the expression of the miR-145, miR-26a, miR-142-3p, miR-21, miR-130a, and miR-146a, and of the apoptosis-related proteins Bid, Bim, Bcl-2, Ciap-2, c-Flip, and Mcl-1 in Bcr-Abl(+) cells." other hsa-mir-146a "Leukemia, Myeloid, Chronic" 27421670 "Here, the L-amino acid oxidase from Calloselasma rhodostoma (CR-LAAO) venom altered the apoptotic machinery regulation by modulating the expression of the miR-145, miR-26a, miR-142-3p, miR-21, miR-130a, and miR-146a, and of the apoptosis-related proteins Bid, Bim, Bcl-2, Ciap-2, c-Flip, and Mcl-1 in Bcr-Abl(+) cells." other hsa-mir-21 "Leukemia, Myeloid, Chronic" 27421670 "Here, the L-amino acid oxidase from Calloselasma rhodostoma (CR-LAAO) venom altered the apoptotic machinery regulation by modulating the expression of the miR-145, miR-26a, miR-142-3p, miR-21, miR-130a, and miR-146a, and of the apoptosis-related proteins Bid, Bim, Bcl-2, Ciap-2, c-Flip, and Mcl-1 in Bcr-Abl(+) cells." other hsa-mir-26a "Leukemia, Myeloid, Chronic" 27421670 "Here, the L-amino acid oxidase from Calloselasma rhodostoma (CR-LAAO) venom altered the apoptotic machinery regulation by modulating the expression of the miR-145, miR-26a, miR-142-3p, miR-21, miR-130a, and miR-146a, and of the apoptosis-related proteins Bid, Bim, Bcl-2, Ciap-2, c-Flip, and Mcl-1 in Bcr-Abl(+) cells." other hsa-mir-21 "Lymphoma, T-Cell, Cutaneous" 27422033 "Our findings not only demonstrate a critical role for IL15-mediated inflammation in cutaneous T-cell lymphomagenesis, but also uncover a new oncogenic regulatory loop in CTCL involving IL15, HDAC1, HDAC6, and miR-21 that shows differential sensitivity to isotype-specific HDAC inhibitors." other hsa-mir-98 "Squamous Cell Carcinoma, Esophageal" 27422937 "AmiR-98 mimic enforced the expression of miRNA-98 and made ESCC cells sensitive to radiotherapy, while anti-miR-98 reversed this process." other hsa-mir-27a Osteosarcoma 27429847 "Moreover, our findings suggested that the modulatory effects of PG on EMMPRIN were due, at least in part, to regulation of an ROS-miR-27a/ZBTB10-Sp1 transcription factor pathway." other hsa-mir-142 Periodontal Diseases 27429973 "In conclusion, five miRNAs have consistently been reported for periodontitis; however, their disease specificity, detectability, and expression in saliva and their importance as noninvasive markers are questionable." other hsa-mir-146a Periodontal Diseases 27429973 "In conclusion, five miRNAs have consistently been reported for periodontitis; however, their disease specificity, detectability, and expression in saliva and their importance as noninvasive markers are questionable." other hsa-mir-155 Periodontal Diseases 27429973 "In conclusion, five miRNAs have consistently been reported for periodontitis; however, their disease specificity, detectability, and expression in saliva and their importance as noninvasive markers are questionable." other hsa-mir-203 Periodontal Diseases 27429973 "In conclusion, five miRNAs have consistently been reported for periodontitis; however, their disease specificity, detectability, and expression in saliva and their importance as noninvasive markers are questionable." other hsa-mir-223 Periodontal Diseases 27429973 "In conclusion, five miRNAs have consistently been reported for periodontitis; however, their disease specificity, detectability, and expression in saliva and their importance as noninvasive markers are questionable." other hsa-mir-16 Glioma 27430517 apigenin inhibits glioma cell growth through promoting miR?16 and suppression of BCL2 and NF-¦ÊB/MMP-9 other hsa-mir-29b Multiple Myeloma 27430753 Paeoniflorin inhibits proliferation and promotes apoptosis of multiple myeloma cells via its effects on microRNAâ€?9b and matrix metalloproteinaseâ€?. other hsa-mir-146b "Leukemia, Lymphocytic, Chronic, B-Cell" 27431016 "When evaluated in CLL cells from 38 patients pre and post treatment with ibrutinib, a subset of these miRNAs (miR-22, miR-34a, miR-146b and miR-181b) was significantly decreased in response to ibrutinib." other hsa-mir-181b "Leukemia, Lymphocytic, Chronic, B-Cell" 27431016 "When evaluated in CLL cells from 38 patients pre and post treatment with ibrutinib, a subset of these miRNAs (miR-22, miR-34a, miR-146b and miR-181b) was significantly decreased in response to ibrutinib." other hsa-mir-22 "Leukemia, Lymphocytic, Chronic, B-Cell" 27431016 "When evaluated in CLL cells from 38 patients pre and post treatment with ibrutinib, a subset of these miRNAs (miR-22, miR-34a, miR-146b and miR-181b) was significantly decreased in response to ibrutinib." other hsa-mir-34a "Leukemia, Lymphocytic, Chronic, B-Cell" 27431016 "When evaluated in CLL cells from 38 patients pre and post treatment with ibrutinib, a subset of these miRNAs (miR-22, miR-34a, miR-146b and miR-181b) was significantly decreased in response to ibrutinib." other hsa-mir-200c Kidney Injury 27431456 Chromium upper tertile was also associated with higher urinary miR-200c (500 copies/μl) and miR-423 (189 copies/μL). other hsa-mir-423 Kidney Injury 27431456 Chromium upper tertile was also associated with higher urinary miR-200c (500 copies/μl) and miR-423 (189 copies/μL). other hsa-mir-223 Spinal Cord Injuries 27432064 Naringenin inhibits spinal cord injury-induced activation of neutrophils through miR-223. other hsa-mir-204 Diabetes Mellitus 27438705 "Its pathological functions have been observed in a few diseases including pulmonary arterial hypertension, diabetes, and various types of cancers." other hsa-mir-204 Endometrial Neoplasms 27438705 "It is believed that miR-204 acts as a tumor-suppressor via promoting apoptosis, conferring the resistance of cancer cells to chemotherapy, and suppressing the self-renewal of cancer stem cells (CSCs) and the epithelial to mesenchymal transition (EMT)." other hsa-mir-204 Hypertension 27438705 "Its pathological functions have been observed in a few diseases including pulmonary arterial hypertension, diabetes, and various types of cancers." other hsa-mir-204 Prostate Neoplasms 27438705 "It is believed that miR-204 acts as a tumor-suppressor via promoting apoptosis, conferring the resistance of cancer cells to chemotherapy, and suppressing the self-renewal of cancer stem cells (CSCs) and the epithelial to mesenchymal transition (EMT)." other hsa-mir-204 Pulmonary Hypertension 27438705 "Its pathological functions have been observed in a few diseases including pulmonary arterial hypertension, diabetes, and various types of cancers." other hsa-mir-122 Hepatitis C Virus Infection 27440892 the expression of CAMP in nonhepatic 293T cells expressing claudin 1 and microRNA miR-122 confers complete propagation of HCV. other hsa-mir-519d "Carcinoma, Lung, Non-Small-Cell" 27447710 "The aim of the study was to evaluate the expression levels of selected miRNAs: miR-26a, miR-29b and miR-519d, and their target gene, matrix metalloproteinase-2 (MMP-2) in patients with non-small cell lung cancer (NSCLC)." other hsa-mir-137 Glioblastoma 27448441 "Furthermore, combining miR-137 and antimiR-10b synergizes with the receptor inhibitory function of aptamer carriers and prevents GSC expansion." other hsa-mir-122 "Carcinoma, Hepatocellular" 27450327 "In this system, we developed a conditionally replicative adenovirus (CRAd) loaded on human umbilical cord-derived mesenchymal stem cells (HUMSCs), in which the CRAd contained an adenovirus E1A gene dual regulated by α-fetoprotein promoter and microRNA-122 target sequence." other hsa-mir-7 Systemic Lupus Erythematosus 27450756 The clearest case is one circRNA CDR1as that serves as sponge of miR-7. other hsa-mir-133a Preterm Labor 27452435 IAI is associated with a transcriptional signature consistent with acute inflammation in the villous trophoblast. other hsa-mir-18a Preterm Labor 27452440 "MALP-2 did not cause apoptosis but did lead to significant secretion of IL-4, IL-6, and IL-8 (P < 0.05, 0.01, 0.001, respectively) and significant changes in miRNA-320a and miRNA-18a (P < 0.05)." other hsa-mir-155 Pancreatic Adenocarcinoma 27456015 "whereas miRNA-30c, miRNA-21, and miRNA-155 levels and CK19 mRNA levels in station 8 nodes were variable and did not correlate with RFS or OS." other hsa-mir-33b Gastric Neoplasms 27456358 Curcumin inhibits cell growth and induces cell apoptosis through upregulation of miR-33b in gastric cancer. other hsa-mir-627 Colon Neoplasms 27458137 "In addition, overexpression of miR-627 or siRNA knockdown of CYP3A4 enhanced the efficacy of irinotecan in growth inhibition and apoptosis induction." other hsa-mir-211 Chromosome 15q13.3 Microdeletion Syndrome 27459725 The 15q13.3 microdeletion syndrome is caused by a 1.5-MB hemizygous microdeletion located on 15q13.3 affecting seven genes: FAN1; MTMR10; TRPM1; miR-211; KLF13; OTUD7A; and CHRNA7 other hsa-mir-326 "Adenocarcinoma, Lung" 27460077 Overexpression of miR-326 reversed cisplatin chemoresistance of LAD cells in vitro and in vivo. other hsa-mir-200 "Carcinoma, Colon" 27460529 Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family. other hsa-mir-16 Osteosarcoma 27460987 "Moreover, GLIPR1 overexpression upregulated miR-16 in osteosarcoma cells." other hsa-mir-146a Asthma 27463381 "Chitin induced the expression of miR-155, miR-146a and miR-21, each of which is known to up-regulate the expression of pro-inflammatory cytokines." other hsa-mir-146a "Carcinoma, Lung" 27463381 "Chitin induced the expression of miR-155, miR-146a and miR-21, each of which is known to up-regulate the expression of pro-inflammatory cytokines." other hsa-mir-155 Asthma 27463381 "Chitin induced the expression of miR-155, miR-146a and miR-21, each of which is known to up-regulate the expression of pro-inflammatory cytokines." other hsa-mir-155 "Carcinoma, Lung" 27463381 "Chitin also induced the expression of the key pattern recognition receptors TLR2 and TLR4. Chitin induced the expression of miR-155, miR-146a and miR-21, each of which is known to up-regulate the expression of pro-inflammatory cytokines." other hsa-mir-21 Asthma 27463381 "Chitin induced the expression of miR-155, miR-146a and miR-21, each of which is known to up-regulate the expression of pro-inflammatory cytokines." other hsa-mir-21 "Carcinoma, Lung" 27463381 "Chitin induced the expression of miR-155, miR-146a and miR-21, each of which is known to up-regulate the expression of pro-inflammatory cytokines." other hsa-mir-126 Rheumatoid Arthritis 27465842 CCN1 induced VEGF expression in osteoblasts and increased endothelial progenitor cells (EPCs) angiogenesis by inhibiting miR-126 via the protein kinase C-alpha (PKC-α) signaling pathway. other hsa-mir-10b Glioblastoma 27467502 Regulation of Cell Proliferation and Migration by miR-203 via GAS41/miR-10b Axis in Human Glioblastoma Cells. other hsa-mir-9 Breast Neoplasms 27468688 Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts. other hsa-mir-155 "Carcinoma, Breast" 27470349 "Therefore, through the anti-glycolytic effect and breakage of the JAK/STAT3/SOCS1 feedback loop via miR-155-5p, 3B may potentially serve as a potential therapeutic agent against breast cancer." other hsa-mir-34a Holt-Oram Syndrome 27471727 This approach allowed to discover complex regulatory circuits involving novel miRNAs and protein coding genes not considered before in the HOS such as miR-34a and miR-30 and their targets. other hsa-mir-195 Intrahepatic Cholangiocarcinoma 27474881 Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model. other hsa-let-7a Cardiomyopathy 27475403 "Six miRNAs seem to be associated with these 2 pathways, which include hsa-miR-19b-1-5p, hsa-miR-1295a, hsa-let-7a-5p, hsa-miR-99b-3p, hsa-miR-16-1-3p, and hsa-miR-34b-3p" other hsa-mir-1295a Cardiomyopathy 27475403 "Six miRNAs seem to be associated with these 2 pathways, which include hsa-miR-19b-1-5p, hsa-miR-1295a, hsa-let-7a-5p, hsa-miR-99b-3p, hsa-miR-16-1-3p, and hsa-miR-34b-3p" other hsa-mir-16-1 Cardiomyopathy 27475403 "Six miRNAs seem to be associated with these 2 pathways, which include hsa-miR-19b-1-5p, hsa-miR-1295a, hsa-let-7a-5p, hsa-miR-99b-3p, hsa-miR-16-1-3p, and hsa-miR-34b-3p" other hsa-mir-19b-1 Cardiomyopathy 27475403 "Six miRNAs seem to be associated with these 2 pathways, which include hsa-miR-19b-1-5p, hsa-miR-1295a, hsa-let-7a-5p, hsa-miR-99b-3p, hsa-miR-16-1-3p, and hsa-miR-34b-3p" other hsa-mir-34b Cardiomyopathy 27475403 "Six miRNAs seem to be associated with these 2 pathways, which include hsa-miR-19b-1-5p, hsa-miR-1295a, hsa-let-7a-5p, hsa-miR-99b-3p, hsa-miR-16-1-3p, and hsa-miR-34b-3p" other hsa-mir-99b Cardiomyopathy 27475403 "Six miRNAs seem to be associated with these 2 pathways, which include hsa-miR-19b-1-5p, hsa-miR-1295a, hsa-let-7a-5p, hsa-miR-99b-3p, hsa-miR-16-1-3p, and hsa-miR-34b-3p" other hsa-mir-125b Psoriasis 27479112 "Based on our bioinformatical pipeline, ubiquitin-specific peptidase 2 was selected as a likely candidate for a mechanistic explanation for psoriasis association." other hsa-mir-29a Liver Cirrhosis 27480597 MiR-29a exhibited anti-fibrotic effect without cell toxicity in vivo and directly suppressed the expression of PDGF-related genes as well as COL1A1 and induced apoptosis of LX-2 cells. other hsa-mir-30d Choriocarcinoma 27481218 "Following transient transfection of mir-30d mimic, the disrupted attachment and outgrowth of JAR spheroids was partially restored in the model." other hsa-mir-558 "Carcinoma, Lung" 27485693 "By contrast, in the cells exposed to 4, 6 or 8 Gy, the administration of miRâ€?58 mimics or AATK specific siRNA significantly promoted cell survival rate and overexpression of AATK reversed this effect." other hsa-mir-206 Rhabdomyosarcoma 27488535 Heme Oxygenase-1 Controls an HDAC4-miR-206 Pathway of Oxidative Stress in Rhabdomyosarcoma. other hsa-mir-17 Allergic Rhinitis 27491928 "The results showed that the levels of miR-19a, but not the rest of the 5 members (miR-17, miR-18a, miR-19b, miR-20a, and miR-92a), were significantly higher in peripheral B cells from AR patients as than in B cells from healthy participants." other hsa-mir-18a Allergic Rhinitis 27491928 "The results showed that the levels of miR-19a, but not the rest of the 5 members (miR-17, miR-18a, miR-19b, miR-20a, and miR-92a), were significantly higher in peripheral B cells from AR patients as than in B cells from healthy participants." other hsa-mir-19b Allergic Rhinitis 27491928 "The results showed that the levels of miR-19a, but not the rest of the 5 members (miR-17, miR-18a, miR-19b, miR-20a, and miR-92a), were significantly higher in peripheral B cells from AR patients as than in B cells from healthy participants." other hsa-mir-20a Allergic Rhinitis 27491928 "The results showed that the levels of miR-19a, but not the rest of the 5 members (miR-17, miR-18a, miR-19b, miR-20a, and miR-92a), were significantly higher in peripheral B cells from AR patients as than in B cells from healthy participants." other hsa-mir-92a Allergic Rhinitis 27491928 "The results showed that the levels of miR-19a, but not the rest of the 5 members (miR-17, miR-18a, miR-19b, miR-20a, and miR-92a), were significantly higher in peripheral B cells from AR patients as than in B cells from healthy participants." other hsa-mir-23a "Adenocarcinoma, Lung" 27492069 "In addition, miR-23a was significantly enriched in the exosomes after mesenchymal transition." other hsa-mir-34c Bone Disease [unspecific] 27492554 "Taken together, our studies suggested that Icariine restored LPS-induced bone loss by downregulating miR-34c level and suppressing JNKs, p38, and NF-kB pathways, which highlighted the potential use of Icariine as a therapeutic agent in the treatment of bacteria-induced bone loss diseases." other hsa-mir-19b Neuroblastoma 27492819 Suppression of miR-19b may enhance the cytotoxic effects of mTOR inhibitors in neuroblastoma cells other hsa-let-7 "Leukemia, Myeloid, Chronic" 27494666 "ADAR1 restores expression of let-7 and efficiently kills LSCs, providing an innovative therapeutic target in CML." other hsa-mir-21 Multiple Myeloma 27494872 miR-21 and miR-221/222 could negatively modulate drug sensitivity of MM cells. other hsa-let-7f Hepatitis C Virus Infection 27496568 "these functional miRNAs, mainly represented by let-7f, miR-145, miR-199a, and miR-221 released from uMSC-Exo, largely contributed to the suppression of HCV RNA replication." other hsa-mir-145 Hepatitis C Virus Infection 27496568 "these functional miRNAs, mainly represented by let-7f, miR-145, miR-199a, and miR-221 released from uMSC-Exo, largely contributed to the suppression of HCV RNA replication." other hsa-mir-199a Hepatitis C Virus Infection 27496568 "these functional miRNAs, mainly represented by let-7f, miR-145, miR-199a, and miR-221 released from uMSC-Exo, largely contributed to the suppression of HCV RNA replication." other hsa-mir-221 Hepatitis C Virus Infection 27496568 "these functional miRNAs, mainly represented by let-7f, miR-145, miR-199a, and miR-221 released from uMSC-Exo, largely contributed to the suppression of HCV RNA replication." other hsa-mir-29b "Carcinoma, Gastric" 27497248 "Taken together, our results suggested that RUNX3-mediated up-regulation of miR-29b inhibited the proliferation and migration of gastric cancer cells by targeting KDM2A, representing a novel molecular mechanism for the tumor suppression action of RUNX3." other hsa-mir-200a Neoplasms [unspecific] 27497669 "In conclusion, LEFTY2 down-regulates MKi67 expression and FAK activity, up-regulates miR-200a and E-cadherin, and is thus a powerful negative regulator of endometrial cell proliferation and migration." other hsa-mir-410 Neuroblastoma 27498840 "In conclusion, the present study demonstrates that the overexpression of SPARC in combination with radiation reduced tumor angiogenesis by downregulating VEGF-A via miR-410." other hsa-let-7 Perlman Syndrome 27498873 we found that Dis3l2 specifically recognizes and degrades uridylated pre-let-7 microRNA other hsa-mir-125b Neoplasms [unspecific] 27500388 "along with modulation of wt-p53 and miR-125b expression, we also show that the exosomes (i.e., wt-p53/exo, miR-125b/exo and combination/exo) have a reprogramed global miRNA profile." other hsa-mir-21 Astrocytoma 27504157 "Our data showed that in 1321N1 cells, β-adrenergic-Epac pathway stimulation up and down-regulated Cx43 and miR-21 expression respectively." other hsa-mir-21 Glioma 27504157 "Our data showed that in 1321N1 cells, E2-adrenergic-Epac pathway stimulation up and down-regulated Cx43 and miR-21 expression respectively." other hsa-mir-4443 "Carcinoma, Breast" 27504971 "We revealed that miR-4443 induced malignancy of breast cancer mainly in chemo-resistance aspect for the very first time, providing a novel biomarker in breast cancer diagnosis and therapy." other hsa-mir-17 Kaposi Sarcoma 27512057 "Here, we provide the first experimental evidence of JMRV miRNAs in vitro and demonstrate that one of these viral miRNAs can mimic the activity of the cellular miR-17/20/106 family." other hsa-mir-17 Multiple Sclerosis 27512057 "Here, we provide the first experimental evidence of JMRV miRNAs in vitro and demonstrate that one of these viral miRNAs can mimic the activity of the cellular miR-17/20/106 family." other hsa-mir-17 Polycystic Kidney Disease 27512774 One of the mechanisms through which the miR-17~92 cluster aggravates to cyst growth is by promoting proliferation of the cyst epithelial cells. other hsa-mir-155 Myelodysplastic Syndromes 27513856 "In the current study, we identified overexpression of c-Fos-targeting miR-34a and miR-155 as the cause of impairment." other hsa-mir-34a Myelodysplastic Syndromes 27513856 "In the current study, we identified overexpression of c-Fos-targeting miR-34a and miR-155 as the cause of impairment." other hsa-mir-29a "Carcinoma, Breast" 27523474 miR-29a may be a potential target for the patients who acquired ADR-resistance during the treatment of breast cancer. other hsa-mir-135a "Carcinoma, Prostate" 27524492 Our data support a model in which hsa-miR-135-1 acts as a potential tumor suppressor in metastatic prostate cancer. other hsa-mir-210 Preeclampsia 27529341 "Some of the most frequently differentially expressed miRs in PE include miR-210, miR-223 and miR-126/126* which associate strongly with the etiological domains of hypoxia, immunology and angiogenesis." other hsa-mir-126 "Leukemia, Lymphoblastic" 27535859 Bioinformatics analysis of microRNA comprehensive regulatory network in B- cell acute lymphoblastic leukemia. other hsa-mir-138 "Carcinoma, Esophageal" 27536892 ¦Á-Solanine Modulates the Radiosensitivity of Esophageal Cancer Cells by Inducing MicroRNA 138 Expression. other hsa-mir-214 "Carcinoma, Colon" 27537384 "MicroRNA-214 suppresses growth, migration and invasion through a novel target, high mobility group AT-hook 1, in human cervical and colorectal cancer cells." other hsa-mir-124 Stroke 27539642 Dynamic Modulation of Microglia/Macrophage Polarization by miR-124 after Focal Cerebral Ischemia. other hsa-mir-503 "Carcinoma, Breast" 27539783 An integrative transcriptomics approach identifies miR-503 as a candidate master regulator of the estrogen response in MCF-7 breast cancer cells. other hsa-mir-1 "Carcinoma, Lung" 27541266 Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling. other hsa-mir-206 "Carcinoma, Lung" 27541266 Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling. other hsa-mir-31 "Carcinoma, Lung" 27541266 Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling. other hsa-mir-21 Vascular Hypertrophy 27542393 MicroRNA-21 Lowers Blood Pressure in Spontaneous Hypertensive Rats by Upregulating Mitochondrial Translation. other hsa-mir-208b Atrial Fibrillation 27545043 miR-208b upregulation interferes with calcium handling in HL-1 atrial myocytes: Implications in human chronic atrial fibrillation. other hsa-mir-21 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 27545281 MicroRNA-21 in laryngeal squamous cell carcinoma: Diagnostic and prognostic features. other hsa-mir-211 Melanoma 27548915 Melanoma miRNA trafficking controls tumour primary niche formation. other hsa-mir-429 "Carcinoma, Renal Cell, Clear-Cell" 27549611 Epithelial-mesenchymal transition-associated microRNA/mRNA signature is linked to metastasis and prognosis in clear-cell renal cell carcinoma. other hsa-mir-146b "Leukemia, Lymphoblastic, Acute, T-Cell" 27550837 MiR-146b negatively regulates migration and delays progression of T-cell acute lymphoblastic leukemia. other hsa-mir-210 "Carcinoma, Adrenocortical" 27550961 Preclinical progress and first translational steps for a liposomal chemotherapy protocol against adrenocortical carcinoma. other hsa-mir-145 Osteogenesis Imperfecta 27551756 Ossotide promotes cell differentiation of human osteoblasts from osteogenesis imperfecta patients by up-regulating miR-145. other hsa-mir-383 "Carcinoma, Lung, Non-Small-Cell" 27551765 MicroRNA-383 is a tumor suppressor and potential prognostic biomarker in human non-small cell lung caner. other hsa-mir-483 "Carcinoma, Ovarian" 27554045 PKC-alpha modulation by miR-483-3p in platinum-resistant ovarian carcinoma cells. other hsa-mir-29b "Carcinoma, Lung, Non-Small-Cell" 27555773 Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins. other hsa-mir-145 "Squamous Cell Carcinoma, Oral" 27557511 "Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline." other hsa-mir-206 Glioblastoma 27558109 MicroRNA-206 Inhibited the Progression of Glioblastoma Through BCL-2. other hsa-let-7a "Diabetes Mellitus, Gestational" 27562513 Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. other hsa-let-7g "Diabetes Mellitus, Gestational" 27562513 Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. other hsa-mir-126 "Diabetes Mellitus, Gestational" 27562513 Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. other hsa-mir-130b "Diabetes Mellitus, Gestational" 27562513 Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. other hsa-mir-148a "Diabetes Mellitus, Gestational" 27562513 Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. other hsa-mir-30c "Diabetes Mellitus, Gestational" 27562513 Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. other hsa-mir-452 "Diabetes Mellitus, Gestational" 27562513 Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. other hsa-mir-139 "Carcinoma, Prostate" 27562849 MiR-139-5p is Increased in the Peripheral Blood of Patients with Prostate Cancer. other hsa-mir-630 "Squamous Cell Carcinoma, Esophageal" 27563011 MiR-630 inhibits invasion and metastasis in esophageal squamous cell carcinoma. other hsa-mir-21 Bronchiolitis Obliterans Syndrome 27564214 Identification of miRNAs Potentially Involved in Bronchiolitis Obliterans Syndrome: A Computational Study. other hsa-mir-34a Bronchiolitis Obliterans Syndrome 27564214 Identification of miRNAs Potentially Involved in Bronchiolitis Obliterans Syndrome: A Computational Study. other hsa-mir-222 "Carcinoma, Lung" 27566197 Panax notoginseng saponins attenuate lung cancer growth in part through modulating the level of Met/miR-222 axis. other hsa-mir-383 "Carcinoma, Ovarian" 27567588 Inhibition of microRNA-383 has tumor suppressive effect in human epithelial ovarian cancer through the action on caspase-2 gene. other hsa-mir-146a Psoriasis 27568078 MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis. other hsa-mir-222 "Carcinoma, Breast" 27569215 Mesenchymal Stem Cell-Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow. other hsa-mir-223 "Carcinoma, Breast" 27569215 Mesenchymal Stem Cell-Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow. other hsa-mir-29a "Adenocarcinoma, Lung" 27569280 Respiratory syncytial virus non-structural protein 1 facilitates virus replication through miR-29a-mediated inhibition of interferon-¦Á receptor. other hsa-mir-21 Autism Spectrum Disorder 27571009 "Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder." other hsa-mir-211 Melanoma 27571736 Pigmented melanosomes are now shown to have a relevant role in establishing a tumour niche in primary melanoma by reprogramming dermal fibroblasts into cancer-associated fibroblasts through the transfer of miR-211 other hsa-mir-107 "Carcinoma, Hepatocellular" 27571925 Heme oxygenase-1 retards hepatocellular carcinoma progression through the microRNA pathway. other hsa-mir-30d "Carcinoma, Hepatocellular" 27571925 Heme oxygenase-1 retards hepatocellular carcinoma progression through the microRNA pathway. other hsa-mir-137 "Squamous Cell Carcinoma, Tongue" 27571935 "MicroRNA-137 suppresses tongue squamous carcinoma cell proliferation, migration and invasion." other hsa-mir-204 Colorectal Carcinoma 27571956 Weighted gene co-expression network analysis of colorectal cancer liver metastasis genome sequencing data and screening of anti-metastasis drugs. other hsa-mir-455 Colorectal Carcinoma 27571956 Weighted gene co-expression network analysis of colorectal cancer liver metastasis genome sequencing data and screening of anti-metastasis drugs. other hsa-mir-195 Neoplasms [unspecific] 27572273 MicroRNA-195 targets VEGFR2 and has a tumor suppressive role in ACHN cells via PI3K/Akt and Raf/MEK/ERK signaling pathways. other hsa-mir-144 "Carcinoma, Esophageal" 27572636 Possible tumor suppressive role of the miR-144/451 cluster in esophageal carcinoma as determined by principal component regression analysis. other hsa-mir-451 "Carcinoma, Esophageal" 27572636 Possible tumor suppressive role of the miR-144/451 cluster in esophageal carcinoma as determined by principal component regression analysis. other hsa-mir-194 Melanoma 27573550 miR-194 is a negative regulator of GEF-H1 pathway in melanoma. other hsa-mir-1246 "Carcinoma, Biliary Tract" 27573701 miR?1246 and miR?4644 in salivary exosome as potential biomarkers for pancreatobiliary tract cancer. other hsa-mir-4644 "Carcinoma, Biliary Tract" 27573701 miR?1246 and miR?4644 in salivary exosome as potential biomarkers for pancreatobiliary tract cancer. other hsa-mir-892b "Carcinoma, Bladder" 27573859 "MicroRNA-892b influences proliferation, migration and invasion of bladder cancer cells by mediating the p19ARF/cyclin D1/CDK6 and Sp-1/MMP-9 pathways." other hsa-mir-195 Glioma 27574009 TGF-¦Â1 regulating miR-205/miR-195 expression affects the TGF-¦Â signal pathway by respectively targeting SMAD2/SMAD7. other hsa-mir-205 Glioma 27574009 TGF-¦Â1 regulating miR-205/miR-195 expression affects the TGF-¦Â signal pathway by respectively targeting SMAD2/SMAD7. other hsa-let-7 "Carcinoma, Breast" 27574028 Let?7 miRNAs sensitize breast cancer stem cells to radiation?induced repression through inhibition of the cyclin?D1/Akt1/Wnt1 signaling pathway. other hsa-mir-494 "Adenocarcinoma, Lung" 27575252 Discriminating between Terminal- and Non-Terminal Respiratory Unit-Type Lung Adenocarcinoma Based on MicroRNA Profiles. other hsa-mir-551b "Adenocarcinoma, Lung" 27575252 Discriminating between Terminal- and Non-Terminal Respiratory Unit-Type Lung Adenocarcinoma Based on MicroRNA Profiles. other hsa-mir-100 "Carcinoma, Hepatocellular" 27577856 MicroRNAs miR-125b and miR-100 suppress metastasis of hepatocellular carcinoma by disrupting the formation of vessels that encapsulate tumour clusters. other hsa-mir-125b "Carcinoma, Hepatocellular" 27577856 MicroRNAs miR-125b and miR-100 suppress metastasis of hepatocellular carcinoma by disrupting the formation of vessels that encapsulate tumour clusters. other hsa-mir-17 Neoplasms [unspecific] 27577994 "miR-17-5p is at the crossroads of aging, longevity and cancer and might represent a promising biomarker or even therapeutic tool and target in this context" other hsa-mir-122 Hepatitis C Virus Infection 27578438 Unraveling the Mysterious Interactions Between Hepatitis C Virus RNA and Liver-Specific MicroRNA-122. other hsa-mir-21 "Carcinoma, Breast" 27579604 Distinct Small RNA Signatures in Extracellular Vesicles Derived from Breast Cancer Cell Lines. other hsa-mir-17 Psoriasis 27579777 miRNA miR-17-92 cluster is differentially regulated in the imiqumod-treated skin but is not required for imiqumod-induced psoriasis-like dermatitis in mice. other hsa-mir-18 Psoriasis 27579777 miRNA miR-17-92 cluster is differentially regulated in the imiqumod-treated skin but is not required for imiqumod-induced psoriasis-like dermatitis in mice. other hsa-mir-19a Psoriasis 27579777 miRNA miR-17-92 cluster is differentially regulated in the imiqumod-treated skin but is not required for imiqumod-induced psoriasis-like dermatitis in mice. other hsa-mir-19b-1 Psoriasis 27579777 miRNA miR-17-92 cluster is differentially regulated in the imiqumod-treated skin but is not required for imiqumod-induced psoriasis-like dermatitis in mice. other hsa-mir-20a Psoriasis 27579777 miRNA miR-17-92 cluster is differentially regulated in the imiqumod-treated skin but is not required for imiqumod-induced psoriasis-like dermatitis in mice. other hsa-mir-92-1 Psoriasis 27579777 miRNA miR-17-92 cluster is differentially regulated in the imiqumod-treated skin but is not required for imiqumod-induced psoriasis-like dermatitis in mice. other hsa-mir-200 "Carcinoma, Renal Cell" 27580029 Loss of fumarate hydratase is associated with suppression of miR-200 and the EMT signature in renal cancer and is associated with poor clinical outcome other hsa-mir-146a Colorectal Carcinoma 27580100 Numb is involved in the non-random segregation of subcellular vesicles in colorectal cancer stem cells. other hsa-mir-30a Multiple Sclerosis 27581464 Disulfiram and Diphenhydramine Hydrochloride Upregulate miR-30a to Suppress IL-17-Associated Autoimmune Inflammation. other hsa-mir-126 Neoplasms [unspecific] 27583885 Potential role of microRNA-126 in the diagnosis of cancers: A systematic review and meta-analysis. other hsa-mir-21 Psoriasis 27586798 the activation of S100A8/A9-dependent C3 complement as well as a miR-21-dependent TIMP-3/TACE pathway leading to TNF-¦Á shedding other hsa-mir-155 Hypoxia 27587248 Effect of miR- 155 on immune- factors and its mechanism in mesenchymal stem cells under hypoxic environment. other hsa-mir-141 "Carcinoma, Prostate" 27589398 Sensitive detection of microRNA in complex biological samples by using two stages DSN-assisted target recycling signal amplification method. other hsa-mir-203 "Carcinoma, Nasopharyngeal" 27589832 A directly negative interaction of miR-203 and ZEB2 modulates tumor stemness and chemotherapy resistance in nasopharyngeal carcinoma. other hsa-mir-148a Hepatitis C Virus Infection 27591428 "miR-148a and miR-30a limit HCV-dependent suppression of the lipid droplet protein, ADRP, in HCV infected cell models." other hsa-mir-30a Chronic Hepatitis C 27591428 "miR-148a and miR-30a limit HCV-dependent suppression of the lipid droplet protein, ADRP, in HCV infected cell models." other hsa-mir-122 "Diabetes Mellitus, Type 2" 27592052 HNF-4¦Á regulated miR-122 contributes to development of gluconeogenesis and lipid metabolism disorders in Type 2 diabetic mice and in palmitate-treated HepG2 cells. other hsa-mir-183 Lung Neoplasms 27593936 TFAP2C promotes lung tumorigenesis and aggressiveness through miR-183- and miR-33a-mediated cell cycle regulation. other hsa-mir-33a Lung Neoplasms 27593936 TFAP2C promotes lung tumorigenesis and aggressiveness through miR-183- and miR-33a-mediated cell cycle regulation. other hsa-mir-582 "Carcinoma, Colon" 27595705 miR-582-5P induces colorectal cancer cell proliferation by targeting adenomatous polyposis coli. other hsa-mir-146a Sepsis 27596437 "systemic inflammation induced an increase in EVs and associated pro-inflammatory miRNAs, including miR-146a and miR-155, in the CSF Interestingly, this was associated with an increase in amount of multivesicular bodies (MVBs) and exosomes per MVB in the CPE cells" other hsa-mir-155 Sepsis 27596437 "systemic inflammation induced an increase in EVs and associated pro-inflammatory miRNAs, including miR-146a and miR-155, in the CSF Interestingly, this was associated with an increase in amount of multivesicular bodies (MVBs) and exosomes per MVB in the CPE cells" other hsa-mir-4687 "Diabetes Mellitus, Type 2" 27597954 Role of miRNAs in Epicardial Adipose Tissue in CAD Patients with T2DM. other hsa-mir-21 Retinoblastoma 27600360 MiR-21 inhibitor suppressed the progression of retinoblastoma via the modulation of PTEN/PI3K/AKT pathway. other hsa-mir-17 Medulloblastoma 27600805 Dicer1 ablation impairs Shh-induced GNP proliferation by disrupting the expression of distinct cell cycle regulator genes that are targets of miR-17/92 cluster members other hsa-mir-18 Medulloblastoma 27600805 Dicer1 ablation impairs Shh-induced GNP proliferation by disrupting the expression of distinct cell cycle regulator genes that are targets of miR-17/92 cluster members other hsa-mir-19a Medulloblastoma 27600805 Dicer1 ablation impairs Shh-induced GNP proliferation by disrupting the expression of distinct cell cycle regulator genes that are targets of miR-17/92 cluster members other hsa-mir-19b-1 Medulloblastoma 27600805 Dicer1 ablation impairs Shh-induced GNP proliferation by disrupting the expression of distinct cell cycle regulator genes that are targets of miR-17/92 cluster members other hsa-mir-20a Medulloblastoma 27600805 Dicer1 ablation impairs Shh-induced GNP proliferation by disrupting the expression of distinct cell cycle regulator genes that are targets of miR-17/92 cluster members other hsa-mir-92-1 Medulloblastoma 27600805 Dicer1 ablation impairs Shh-induced GNP proliferation by disrupting the expression of distinct cell cycle regulator genes that are targets of miR-17/92 cluster members other hsa-mir-200c Ovarian Neoplasms 27601996 miR-200c Regulation of Metastases in Ovarian Cancer: Potential Role in Epithelial and Mesenchymal Transition. other hsa-mir-143 "Carcinoma, Lung, Non-Small-Cell" 27602093 miR-143 suppresses the proliferation of NSCLC cells by inhibiting the epidermal growth factor receptor. other hsa-mir-146b "Carcinoma, Thyroid, Anaplastic" 27602131 p21 participates in the regulation of anaplastic thyroid cancer cell proliferation by miR-146b. other hsa-mir-27a Lung Neoplasms 27602162 Genistein inhibits A549 human lung cancer cell proliferation via miR-27a and MET signaling. other hsa-mir-155 Neoplasms [unspecific] 27602769 MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/¦Â-catenin signaling pathways. other hsa-mir-21 Chronic Kidney Disease 27610006 TGF-¦Â1/Smads and miR-21 in Renal Fibrosis and Inflammation. other hsa-mir-10b Lymphoma 27611973 Profile of Exosomal and Intracellular microRNA in Gamma-Herpesvirus-Infected Lymphoma Cell Lines. other hsa-mir-143 Lymphoma 27611973 Profile of Exosomal and Intracellular microRNA in Gamma-Herpesvirus-Infected Lymphoma Cell Lines. other hsa-mir-27a Pulmonary Hypertension 27612006 Peroxisome Proliferator-Activated Receptor ¦Ã Regulates the V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 1/microRNA-27a Axis to Reduce Endothelin-1 and Endothelial Dysfunction in the Sickle Cell Mouse Lung. other hsa-mir-125b "Leukemia, Promyelocytic, Acute" 27613090 Identification of miR-125b targets involved in acute promyelocytic leukemia cell proliferation. other hsa-mir-29b Schizophrenia 27613806 Epistatic and Independent Effects on Schizophrenia-Related Phenotypes Following Co-disruption of the Risk Factors Neuregulin-1 ¡Á DISC1. other hsa-mir-122 Chronic Hepatitis C 27614072 TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus. other hsa-mir-7 "Carcinoma, Hepatocellular" 27614453 The circular RNA ciRS-7 (Cdr1as) acts as a risk factor of hepatic microvascular invasion in hepatocellular carcinoma. other hsa-mir-616 Coronary Artery Disease 27615006 Relationship of microRNA 616 gene polymorphism with prognosis of patients with premature coronary artery disease. other hsa-mir-141 Melanoma 27616325 Trans-nonachlor decreases miR-141-3p levels in human melanocytes in vitro promoting melanoma cell characteristics and shows a multigenerational impact on miR-8 levels in Drosophila. other hsa-mir-429 "Carcinoma, Renal Cell" 27619681 MiR-429 is linked to metastasis and poor prognosis in renal cell carcinoma by affecting epithelial-mesenchymal transition. other hsa-mir-92a Melanoma 27620505 miR-92a-3p and MYCBP2 are involved in MS-275-induced and c-myc-mediated TRAIL-sensitivity in melanoma cells. other hsa-mir-196a "Carcinoma, Esophageal" 27621035 Inhibition of miR-196a affects esophageal cancer cell growth in vitro. other hsa-mir-100 Vascular Injuries 27622243 Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair. other hsa-mir-147 Vascular Injuries 27622243 Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair. other hsa-mir-21 Vascular Injuries 27622243 Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair. other hsa-mir-222 Vascular Injuries 27622243 Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair. other hsa-mir-27a Vascular Injuries 27622243 Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair. other hsa-mir-10b Cardiovascular Diseases [unspecific] 27624142 Potential role of microRNA-10b down-regulation in cardiomyocyte apoptosis in aortic stenosis patients. other hsa-mir-4787 "Carcinoma, Pancreatic" 27624777 Inhibition of S-Adenosylmethionine-Dependent Methyltransferase Attenuates TGF¦Â1-Induced EMT and Metastasis in Pancreatic Cancer: Putative Roles of miR-663a and miR-4787-5p. other hsa-mir-663a "Carcinoma, Pancreatic" 27624777 Inhibition of S-Adenosylmethionine-Dependent Methyltransferase Attenuates TGF¦Â1-Induced EMT and Metastasis in Pancreatic Cancer: Putative Roles of miR-663a and miR-4787-5p. other hsa-mir-1284 "Carcinoma, Gastric" 27627897 MicroRNA-1284 inhibits proliferation and induces apoptosis in SGC-7901 human gastric cancer cells. other hsa-mir-424 "Squamous Cell Carcinoma, Esophageal" 27628042 MiR-424-5p participates in esophageal squamous cell carcinoma invasion and metastasis via SMAD7 pathway mediated EMT. other hsa-mir-490 "Squamous Cell Carcinoma, Skin or Unspecific" 27629145 Poly r(C) binding protein is post-transcriptionally repressed by MiR-490-3p to potentiate squamous cell carcinoma. other hsa-mir-143 Colorectal Carcinoma 27629291 "we showed the importance of interactions between TP53, miR-143, KRAS, BCL2, and PLK1 with respect to colorectal cancer using bioinformatics approach" other hsa-mir-31 "Carcinoma, Colon" 27630355 Efficacy and Toxicity of Panitumumab After Progression on Cetuximab and Predictive Value of MiR-31-5p in Metastatic Wild-type KRAS Colorectal Cancer Patients. other hsa-mir-196a Huntington Disease 27631085 miR-196a Ameliorates Cytotoxicity and Cellular Phenotype in Transgenic Huntington's Disease Monkey Neural Cells. other hsa-mir-378 Myelodysplastic Syndromes 27633496 miR-378 inhibits cell growth and enhances apoptosis in human myelodysplastic syndromes. other hsa-mir-181a Glioblastoma 27633853 MicroRNA-181a promotes proliferation and inhibits apoptosis by suppressing CFIm25 in osteosarcoma. other hsa-mir-34a Lung Fibrosis 27635790 miR-34a Inhibits Lung Fibrosis by Inducing Lung Fibroblast Senescence. other hsa-mir-223 Ischemia-Reperfusion Injury 27635859 Neuroprotective effect of ischemic preconditioning via modulating the expression of cerebral miRNAs against transient cerebral ischemia in diabetic rats. other hsa-mir-21 "Scleroderma, Systemic" 27637490 Inhibition of MicroRNA-21 induces apoptosis in dermal fibroblasts of patients with systemic sclerosis. other hsa-mir-302f Congenital Heart Diseases 27637763 Copy-number variant analysis of classic heterotaxy highlights the importance of body patterning pathways. other hsa-mir-122 Hepatitis C Virus Infection 27641985 "The history of hepatitis C virus (HCV): Basic research reveals unique features in phylogeny, evolution and the viral life cycle with new perspectives for epidemic control." other hsa-mir-214 "Carcinoma, Lung" 27642589 cir-ITCH acted as sponge of oncogenic miR-7 and miR-214 to enhance ITCH expression and thus suppressed the activation of Wnt/¦Â-catenin signaling other hsa-mir-7 "Carcinoma, Lung" 27642589 cir-ITCH acted as sponge of oncogenic miR-7 and miR-214 to enhance ITCH expression and thus suppressed the activation of Wnt/¦Â-catenin signaling other hsa-mir-26a "Carcinoma, Lung, Small-Cell" 27644194 KH-type splicing regulatory protein (KHSRP) contributes to tumorigenesis by promoting miR-26a maturation in small cell lung cancer. other hsa-mir-221 Atherosclerosis 27644883 Human aortic smooth muscle cell-derived exosomal miR-221/222 inhibits autophagy via a PTEN/Akt signaling pathway in human umbilical vein endothelial cells. other hsa-mir-222 Atherosclerosis 27644883 Human aortic smooth muscle cell-derived exosomal miR-221/222 inhibits autophagy via a PTEN/Akt signaling pathway in human umbilical vein endothelial cells. other hsa-mir-124a Neuropathic Pain 27646435 miR-124a and miR-155 enhance differentiation of regulatory T cells in patients with neuropathic pain. other hsa-mir-155 Neuropathic Pain 27646435 miR-124a and miR-155 enhance differentiation of regulatory T cells in patients with neuropathic pain. other hsa-mir-106b Multiple Myeloma 27647143 Integrative analysis of signaling pathways and diseases associated with the miR-106b/25 cluster and their function study in?berb?erine-induced multiple myeloma cells. other hsa-mir-25 Multiple Myeloma 27647143 Integrative analysis of signaling pathways and diseases associated with the miR-106b/25 cluster and their function study in?berb?erine-induced multiple myeloma cells. other hsa-let-7 Wilms Tumor 27647875 uridylated pre-let-7 miRNAs and mRNAs are targeted by the 3' to 5' exoribonuclease DIS3L2 other hsa-mir-323b "Leukemia, Lymphoblastic, Acute, B-Cell" 27649261 MiR-pharmacogenetics of methotrexate in childhood B-cell acute lymphoblastic leukemia. other hsa-mir-137 Glioblastoma 27649660 Circulating microRNA-137 is a potential biomarker for human glioblastoma. other hsa-mir-137 Schizophrenia 27650867 MicroRNA-137 Inhibits EFNB2 Expression Affected by a Genetic Variant and Is Expressed Aberrantly in Peripheral Blood of Schizophrenia Patients. other hsa-mir-205 Keloid 27651436 Upregulation of microRNA-205 suppresses vascular endothelial growth factor expression-mediated PI3K/Akt signaling transduction in human keloid fibroblasts. other hsa-mir-125a "Carcinoma, Breast" 27651454 Structural dynamics control the MicroRNA maturation pathway. other hsa-mir-628 Cardiac Allograft Vasculopathy 27653298 MicroRNA 628-5p as a Novel Biomarker for Cardiac Allograft Vasculopathy. other hsa-mir-4697 Parkinson Disease 27653855 "SIPA1L2, MIR4697, GCH1 and VPS13C loci and risk of Parkinson's diseases in Iranian population: A case-control study." other hsa-mir-203 "Carcinoma, Ovarian" 27655286 MiR-203 promotes the growth and migration of ovarian cancer cells by enhancing glycolytic pathway. other hsa-mir-205 Endometrial Neoplasms 27655663 Locked nucleic acid-inhibitor of miR-205 decreases endometrial cancer cells proliferation in vitro and in vivo. other hsa-let-7 Neoplasms [unspecific] 27659051 "Several proteins known to bind immature forms of these let-7 miRNAs were identified, but with an improved coverage compared to previous studies" other hsa-let-7a Neoplasms [unspecific] 27659051 "Several proteins known to bind immature forms of these let-7 miRNAs were identified, but with an improved coverage compared to previous studies" other hsa-let-7g Neoplasms [unspecific] 27659051 "Several proteins known to bind immature forms of these let-7 miRNAs were identified, but with an improved coverage compared to previous studies" other hsa-mir-22 "Carcinoma, Gastric" 27662840 NTRK2 is an oncogene and associated with microRNA-22 regulation in human gastric cancer cell lines. other hsa-mir-27b Hepatitis C Virus Infection 27665576 Lipoprotein lipase liberates free fatty acids to inhibit HCV infection and prevent hepatic lipid accumulation. other hsa-mir-374 "Carcinoma, Pancreatic" 27665739 "MicroRNA miR-374, a potential radiosensitizer for carbon ion beam radiotherapy." other hsa-let-7g Osteoporosis 27665867 An insertion/deletion polymorphism within the 3'?untranslated region of COL1A2 confers susceptibility to osteoporosis. other hsa-mir-200 "Carcinoma, Colon" 27666412 Colorectal cancer cell-derived microRNA200 modulates the resistance of adjacent blood endothelial barriers in?vitro. other hsa-mir-424 "Carcinoma, Lung, Non-Small-Cell" 27666545 Effects of miR-424 on Proliferation and Migration Abilities in Non-small Cell Lung Cancer A549 Cells and Its Molecular Mechanism. other hsa-mir-21 "Cardiomyopathy, Ischemic" 27666568 "Trimetazidine protects against cardiac ischemia/reperfusion injury via effects on cardiac miRNA?21 expression, Akt and the Bcl?2/Bax pathway." other hsa-mir-743a Wilms Tumor 27667021 Proliferation of metanephric mesenchymal cells is inhibited by miR-743a-mediated WT1 suppression in vitro. other hsa-mir-139 Primary Biliary Cirrhosis 27668889 "MiR-139-5p is associated with inflammatory regulation through c-FOS suppression, and contributes to the progression of primary biliary cholangitis." other hsa-mir-122 "Fatty Liver, Non-Alcoholic" 27669236 miR33a/miR33b* and miR122 as Possible Contributors to Hepatic Lipid Metabolism in Obese Women with Nonalcoholic Fatty Liver Disease. other hsa-mir-33a "Fatty Liver, Non-Alcoholic" 27669236 miR33a/miR33b* and miR122 as Possible Contributors to Hepatic Lipid Metabolism in Obese Women with Nonalcoholic Fatty Liver Disease. other hsa-mir-33b "Fatty Liver, Non-Alcoholic" 27669236 miR33a/miR33b* and miR122 as Possible Contributors to Hepatic Lipid Metabolism in Obese Women with Nonalcoholic Fatty Liver Disease. other hsa-mir-146a Muscular Dystrophy 27671199 Chronic alcohol exposure induces muscle atrophy (myopathy) in zebrafish and alters the expression of microRNAs targeting the Notch pathway in skeletal muscle. other hsa-mir-132 "Carcinoma, Ovarian" 27673409 "MicroRNA and long non-coding RNA have potential clinical utility in the diagnosis of ovarian cancer and predicting prognosis, metastasis, recurrence, and response to therapy" other hsa-mir-26a "Carcinoma, Ovarian" 27673409 "MicroRNA and long non-coding RNA have potential clinical utility in the diagnosis of ovarian cancer and predicting prognosis, metastasis, recurrence, and response to therapy" other hsa-mir-126 Hyperglycemia 27673690 Hyperglycemia and Advanced Glycation End Products Regulate miR-126 Expression in Endothelial Progenitor Cells. other hsa-mir-223 Liver Injury 27679493 MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6-p47phox-oxidative stress pathway in neutrophils. other hsa-mir-210 Preeclampsia 27683514 Predictive value of miR-210 as a novel biomarker for pre-eclampsia: a systematic review protocol. other hsa-mir-155 Hypertension 27683672 Vascular mineralocorticoid receptor regulates microRNA-155 to promote vasoconstriction and rising blood pressure with aging. other hsa-mir-221 "Carcinoma, Breast" 27686606 A small RNA (miR-221) target was determined via the impedimetric measurement of the hybridization event in a label-free and PCR-free approach other hsa-mir-22 Heart Failure 27687198 Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction. other hsa-mir-10a Autoimmune Diseases [unspecific] 27687891 "MicroRNAs such as miR-155, miR-126, and miR-10a also exert an important influence on the differentiation, development, and immunological functions of Tregs" other hsa-mir-126 Autoimmune Diseases [unspecific] 27687891 "MicroRNAs such as miR-155, miR-126, and miR-10a also exert an important influence on the differentiation, development, and immunological functions of Tregs" other hsa-mir-155 Autoimmune Diseases [unspecific] 27687891 "MicroRNAs such as miR-155, miR-126, and miR-10a also exert an important influence on the differentiation, development, and immunological functions of Tregs" other hsa-mir-367 "Carcinoma, Hepatocellular" 27688096 The miR-367-3p Increases Sorafenib Chemotherapy Efficacy to Suppress Hepatocellular Carcinoma Metastasis through Altering the Androgen Receptor Signals. other hsa-mir-21 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 27688683 "Metformin significantly inhibited FaDu cell proliferation , possibly via downregulation of miR-21-5p and upregulation of PDCD4" other hsa-mir-146a Cystic Fibrosis 27689251 "miR-146a, miR-155, miR-370, and miR-708 Are CFTR-Dependent, Predicted FOXO1 Regulators and Change at Onset of CFRDs." other hsa-mir-155 Cystic Fibrosis 27689251 "miR-146a, miR-155, miR-370, and miR-708 Are CFTR-Dependent, Predicted FOXO1 Regulators and Change at Onset of CFRDs." other hsa-mir-370 Cystic Fibrosis 27689251 "miR-146a, miR-155, miR-370, and miR-708 Are CFTR-Dependent, Predicted FOXO1 Regulators and Change at Onset of CFRDs." other hsa-mir-708 Cystic Fibrosis 27689251 "miR-146a, miR-155, miR-370, and miR-708 Are CFTR-Dependent, Predicted FOXO1 Regulators and Change at Onset of CFRDs." other hsa-mir-122 Hepatitis C Virus Infection 27692039 Proposed update to the taxonomy of the genera Hepacivirus and Pegivirus within the Flaviviridae family. other hsa-mir-195 Alzheimer Disease 27693395 MiR-195 dependent roles of mitofusin2 in the mitochondrial dysfunction of hippocampal neurons in SAMP8 mice. other hsa-let-7a "Carcinoma, Hepatocellular" 27693636 Hepatitis B virus mRNAs functionally sequester let-7a and enhance hepatocellular carcinoma. other hsa-mir-338 "Carcinoma, Hepatocellular" 27694002 Down-regulation of microRNA-338-3p promoted angiogenesis in hepatocellular carcinoma. other hsa-mir-200 "Carcinoma, Lung" 27694892 ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis. other hsa-mir-126 "Diabetes Mellitus, Type 2" 27696070 MicroRNA-126 and micro-/macrovascular complications of type 1 diabetes in the EURODIAB Prospective Complications Study. other hsa-mir-494 "Leukemia, Myeloid, Acute" 27696394 MicroRNA-494 Activation Suppresses Bone Marrow Stromal Cell-Mediated Drug Resistance in Acute Myeloid Leukemia Cells. other hsa-mir-133b "Carcinoma, Gastric" 27696637 MiR-133b inhibits growth of human gastric cancer cells by silencing pyruvate kinase muscle-splicer polypyrimidine tract-binding protein 1. other hsa-mir-155 Systemic Lupus Erythematosus 27697141 Follicular T helper cells and IL-21 in rheumatic diseases. other hsa-mir-21 Systemic Lupus Erythematosus 27697141 Follicular T helper cells and IL-21 in rheumatic diseases. other hsa-mir-222 "Carcinoma, Breast" 27699665 miR-222 induces Adriamycin resistance in breast cancer through PTEN/Akt/p27kip1 pathway. other hsa-mir-20b "Carcinoma, Esophageal" 27701465 "MicroRNA-20b (miR-20b) Promotes the Proliferation, Migration, Invasion, and Tumorigenicity in Esophageal Cancer Cells via the Regulation of Phosphatase and Tensin Homologue Expression." other hsa-mir-129 Biliary Atresia 27706677 Effect of miR-29c and miR-129-5p on epithelial-mesenchymal transition in experimental biliary atresia mouse models. other hsa-mir-29c Biliary Atresia 27706677 Effect of miR-29c and miR-129-5p on epithelial-mesenchymal transition in experimental biliary atresia mouse models. other hsa-mir-137 Schizophrenia 27706734 Association between miR-137 polymorphism and risk of schizophrenia: a meta-analysis. other hsa-mir-21 Myocardial Infarction 27708252 Effects of mir-21 on Cardiac Microvascular Endothelial Cells After Acute Myocardial Infarction in Rats: Role of Phosphatase and Tensin Homolog (PTEN)/Vascular Endothelial Growth Factor (VEGF) Signal Pathway. other hsa-mir-133b "Carcinoma, Renal Cell" 27710896 miRNA-133b and miRNA-135a induce apoptosis via the JAK2/STAT3 signaling pathway in human renal carcinoma cells. other hsa-mir-135a "Carcinoma, Renal Cell" 27710896 miRNA-133b and miRNA-135a induce apoptosis via the JAK2/STAT3 signaling pathway in human renal carcinoma cells. other hsa-mir-155 "Diabetes Mellitus, Type 2" 27711113 MiR-155 Enhances Insulin Sensitivity by Coordinated Regulation of Multiple Genes in Mice. other hsa-mir-877 Liver Injury 27713024 MicroRNA-877-5p is involved in the trovafloxacin-induced liver injury. other hsa-mir-572 Neuroblastoma 27716787 Fluoxetine Increases the Expression of miR-572 and miR-663a in Human Neuroblastoma Cell Lines. other hsa-mir-663a Neuroblastoma 27716787 Fluoxetine Increases the Expression of miR-572 and miR-663a in Human Neuroblastoma Cell Lines. other hsa-mir-539 "Carcinoma, Hepatocellular" 27717846 microRNA-539 suppresses tumor growth and tumorigenesis and overcomes arsenic trioxide resistance in hepatocellular carcinoma. other hsa-mir-155 "Carcinoma, Cervical" 27717891 The rs767649 polymorphism in the promoter of miR-155 contributes to the decreased risk for cervical cancer in a Chinese population. other hsa-mir-378 Obesity 27721392 DNA methylation landscape of fat deposits and fatty acid composition in obese and lean pigs. other hsa-mir-21 Epilepsy 27725160 Increased precursor microRNA-21 following status epilepticus can compete with mature microRNA-21 to alter translation. other hsa-mir-21 "Carcinoma, Prostate" 27725205 "Methylated urolithin A, the modified ellagitannin-derived metabolite, suppresses cell viability of DU145 human prostate cancer cells via targeting miR-21." other hsa-mir-34a "Carcinoma, Hepatocellular" 27725225 Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells. other hsa-mir-140 Gout 27727249 microRNA-140 Inhibits Inflammation and Stimulates Chondrogenesis in a Model of Interleukin 1¦Â-induced Osteoarthritis. other hsa-mir-30 "Carcinoma, Gastric" 27729002 miR-30 functions as an oncomiR in gastric cancer cells through regulation of P53-mediated mitochondrial apoptotic pathway. other hsa-mir-372 "Carcinoma, Prostate" 27730751 Repression of MicroRNA-372 by Arsenic Sulphide Inhibits Prostate Cancer Cell Proliferation and Migration through Regulation of large tumour suppressor kinase 2. other hsa-mir-224 Chronic Hepatitis B 27731343 MicroRNA-based diagnostic tools for advanced fibrosis and cirrhosis in patients with chronic hepatitis B and C. other hsa-mir-224 Chronic Hepatitis C 27731343 MicroRNA-based diagnostic tools for advanced fibrosis and cirrhosis in patients with chronic hepatitis B and C. other hsa-mir-221 Inflammation 27731391 Epithelial cell-derived microvesicles activate macrophages and promote inflammation via microvesicle-containing microRNAs. other hsa-mir-940 "Carcinoma, Breast, Triple Negative" 27731867 MiR-940 Inhibited Cell Growth and Migration in Triple-Negative Breast Cancer. other hsa-mir-9501 "Carcinoma, Lung, Non-Small-Cell" 27734264 "The novel miR-9501 inhibits cell proliferation, migration and activates apoptosis in non-small cell lung cancer." other hsa-mir-6126 "Carcinoma, Ovarian" 27742688 Ubiquitous Release of Exosomal Tumor Suppressor miR-6126 from Ovarian Cancer Cells. other hsa-mir-181c Heart Failure 27742689 Role of microRNA in metabolic shift during heart failure. other hsa-mir-378 Heart Failure 27742689 Role of microRNA in metabolic shift during heart failure. other hsa-mir-24 "Carcinoma, Gastric" 27743162 miR-24-3p Regulates Progression of Gastric Mucosal Lesions and Suppresses Proliferation and Invasiveness of N87 Via Peroxiredoxin 6. other hsa-mir-223 "Carcinoma, Bladder" 27744452 Ginkgolide B Inhibits Human Bladder Cancer Cell Migration and Invasion Through MicroRNA-223-3p. other hsa-mir-210 Preeclampsia 27746364 "Evaluation of MicroRNA-210 and Protein tyrosine phosphatase, non-receptor type 2 in Pre-eclampsia." other hsa-mir-126 Atherosclerosis 27748840 Paeonol promotes microRNA-126 expression to inhibit monocyte adhesion to ox-LDL-injured vascular endothelial cells and block the activation of the PI3K/Akt/NF-¦ÊB pathway. other hsa-mir-182 "Carcinoma, Ovarian" 27748882 Downregulation of DNMT3a expression increases miR-182-induced apoptosis of ovarian cancer through caspase-3?and?caspase-9-mediated apoptosis and DNA damage response. other hsa-let-7a "Carcinoma, Cervical" 27748903 Let?7a suppresses cell proliferation via the TGF?¦Â/SMAD signaling pathway in cervical cancer. other hsa-mir-100 "Carcinoma, Ovarian" 27748936 miR-100 resensitizes resistant epithelial ovarian cancer to cisplatin. other hsa-mir-140 Infection [unspecific] 27749761 Microrna Expression Profiling of Macrophage Line Raw264.7 Infected by Candida Albicans. other hsa-mir-29a Vascular Disease [unspecific] 27752152 Dynamic alteration of microRNA in high phosphorus induced calcification of vascular smooth muscle cell. other hsa-mir-145 Multiple Sclerosis 27752929 miR-145 and miR20a-5p Potentially Mediate Pleiotropic Effects of Interferon-Beta Through Mitogen-Activated Protein Kinase Signaling Pathway in Multiple Sclerosis Patients. other hsa-mir-20a Multiple Sclerosis 27752929 miR-145 and miR20a-5p Potentially Mediate Pleiotropic Effects of Interferon-Beta Through Mitogen-Activated Protein Kinase Signaling Pathway in Multiple Sclerosis Patients. other hsa-mir-181b "Aortic Aneurysm, Abdominal" 27756793 MicroRNA-181b Controls Atherosclerosis and Aneurysms Through Regulation of TIMP-3 and Elastin. other hsa-mir-21 Glioblastoma 27757032 Pluronic-based micelle encapsulation potentiates myricetin-induced cytotoxicity in human glioblastoma cells. other hsa-mir-30a "Diabetes Mellitus, Type 2" 27758866 Mitochondrial Activity in Human White Adipocytes Is Regulated by the Ubiquitin Carrier Protein 9/microRNA-30a Axis. other hsa-mir-376c "Squamous Cell Carcinoma, Head and Neck" 27760788 Dysregulation of RUNX2/Activin-A Axis upon miR-376c Downregulation Promotes Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma. other hsa-mir-155 Chronic Hepatitis C 27765085 Differential Expression of MicroRNAs in Hepatitis C Virus-Mediated Liver Disease Between African Americans and Caucasians: Implications for Racial Health Disparities. other hsa-mir-145 Pancreatic Adenocarcinoma 27765914 MiRNA-145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells. other hsa-mir-145 "Squamous Cell Carcinoma, Lung" 27765924 Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) coordinately targeted MTDH in lung squamous cell carcinoma. other hsa-mir-214 Sezary Disease 27766406 "CD164 identifies CD4+ T cells highly expressing genes associated with malignancy in S¨¦zary syndrome: the S¨¦zary signature genes, FCRL3, Tox, and miR-214." other hsa-mir-146a Colorectal Carcinoma 27769860 "microRNA-146a inhibits proliferation, migration and invasion of human cervical and colorectal cancer cells." other hsa-mir-9 "Leukemia, Myeloid, Acute" 27770540 A minicircuitry of microRNA-9-1 and RUNX1-RUNX1T1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia. other hsa-mir-203 "Carcinoma, Colon" 27771718 Sodium Butyrate Upregulates miR-203 Expression to Exert Anti-Proliferation Effect on Colorectal Cancer Cells. other hsa-let-7 "Carcinoma, Endometrial" 27775072 "Metformin acts by upregulating microRNA let-7 through AMPK activation, leading to degradation of H19 long noncoding RNA, which normally binds to and inactivates SAHH" other hsa-mir-29b "Leukemia, Biphenotypic, Acute" 27775550 MicroRNA-29b mediates altered innate immune development in acute leukemia. other hsa-mir-143 Atherosclerosis 27775792 miR-143 is involved in endothelial cell dysfunction through suppression of glycolysis and correlated with atherosclerotic plaques formation. other hsa-mir-92b "Carcinoma, Lung, Non-Small-Cell" 27775799 Regulation of Twist in the metastasis of non-small cell lung cancer by miR-92b. other hsa-mir-155 "Carcinoma, Thyroid, Papillary" 27777199 Expression of microRNA-155 in papillary thyroid carcinoma and its clinical significance. other hsa-mir-29c Endometriosis 27778641 Progesterone Resistance in Endometriosis Is Modulated by the Altered Expression of MicroRNA-29c and FKBP4. other hsa-mir-361 "Carcinoma, Lung, Non-Small-Cell" 27779659 "microRNA-361 targets Wilms' tumor 1 to inhibit the growth, migration and invasion of non-small-cell lung cancer cells." other hsa-mir-129 "Carcinoma, Prostate" 27779679 miR-129 predicts prognosis and inhibits cell growth in human prostate carcinoma. other hsa-mir-27a "Carcinoma, Breast" 27779715 miR-27a-mediated antiproliferative effects of metformin on the breast cancer cell line MCF-7. other hsa-mir-106a Neoplasms [unspecific] 27780637 MiR-106a: Promising biomarker for cancer. other hsa-mir-17 Neoplasms [unspecific] 27780637 MiR-106a: Promising biomarker for cancer. other hsa-mir-7 "Leukemia, Myeloid, Acute" 27784745 Mutational Landscape and Gene Expression Patterns in Adult Acute Myeloid Leukemias with Monosomy 7 as a Sole Abnormality. other hsa-let-7i Acute Ischemic Stroke 27784773 Leukocyte response is regulated by microRNA let7i in patients with acute ischemic stroke. other hsa-let-7 "Carcinoma, Colon" 27789274 "H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-¦Â-Catenin Signaling in Colorectal Cancer." other hsa-mir-206 Vascular Hypertrophy 27789288 Bladder overactivity involves overexpression of MicroRNA 132 and nerve growth factor. other hsa-mir-130a Myocardial Infarction 27789328 Resveratrol increases microRNA-130a expression to promote angiogenesis and improve heart functions in mice after myocardial infarction. other hsa-mir-126 Vascular Disease [unspecific] 27789478 MicroRNA-126a Directs Lymphangiogenesis Through Interacting With Chemokine and Flt4 Signaling in Zebrafish. other hsa-mir-125b Tuberculosis 27789724 Downregulation of hsa-miR-337-3p and hsa-miR-125b-5p by miRNA sponges improved IL-23-mediated expansion of V¦Ã2V¦Ä2 T cells and restored the ability of these cells to produce anti-tuberculosis cytokines other hsa-mir-337 Tuberculosis 27789724 Downregulation of hsa-miR-337-3p and hsa-miR-125b-5p by miRNA sponges improved IL-23-mediated expansion of V¦Ã2V¦Ä2 T cells and restored the ability of these cells to produce anti-tuberculosis cytokines other hsa-mir-203a Gastric Cardia Adenocarcinoma 27791400 Downregulation of Potential Tumor Suppressor miR-203a by Promoter Methylation Contributes to the Invasiveness of Gastric Cardia Adenocarcinoma. other hsa-mir-192 "Carcinoma, Colon" 27793841 Phospholipase D1 Acts through Akt/TopBP1 and RB1 to Regulate the E2F1-Dependent Apoptotic Program in Cancer Cells. other hsa-mir-4465 "Carcinoma, Colon" 27793841 Phospholipase D1 Acts through Akt/TopBP1 and RB1 to Regulate the E2F1-Dependent Apoptotic Program in Cancer Cells. other hsa-mir-489 "Carcinoma, Pancreatic" 27793842 KRAS/NF-¦ÊB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis. other hsa-mir-142 "Lymphoma, Burkitt" 27796281 Epstein-Barr Virus (EBV)-BamHI-A Rightward Transcript (BART)-6 and Cellular MicroRNA-142 Synergistically Compromise Immune Defense of Host Cells in EBV-Positive Burkitt Lymphoma. other hsa-mir-155 IgA Nephropathy 27796698 MicroRNA-155-induced T lymphocyte subgroup drifting in IgA nephropathy. other hsa-mir-146a Alzheimer Disease 27797173 Dipeptidyl Vinyl Sulfone as a Novel Chemical Tool to Inhibit HMGB1/NLRP3-Inflammasome and Inflamma-miRs in A¦Â-Mediated Microglial Inflammation. other hsa-mir-21 "Carcinoma, Colon" 27798874 Prognostic Significance of MicroRNA-21 Expression in Patients with Unresectable Metastatic Colon Cancer. other hsa-mir-324 "Carcinoma, Breast" 27798879 MicroRNA-324 in Human Cancer: miR-324-5p and miR-324-3p Have Distinct Biological Functions in Human Cancer. other hsa-mir-193b "Carcinoma, Renal Cell" 27802451 MicroRNA 193b-3p as a predictive biomarker of chronic kidney disease in patients undergoing radical nephrectomy for renal cell carcinoma. other hsa-mir-21 Ischemia-Reperfusion Injury 27804287 Fluorescent Nanocomposite for Visualizing Cross-Talk between MicroRNA-21 and Hydrogen Peroxide in Ischemia-Reperfusion Injury in Live Cells and In Vivo. other hsa-mir-19b Heart Failure 27805004 miR-19b Regulates Ventricular Action Potential Duration in Zebrafish. other hsa-mir-122 Chronic Hepatitis C 27805315 Inducing Hepatitis C Virus Resistance After Pig Liver Transplantation-A Proof of Concept of Liver Graft Modification Using Warm Ex Vivo Perfusion. other hsa-mir-124 "Carcinoma, Cervical" 27806357 Virtues and Weaknesses of DNA Methylation as a Test for Cervical Cancer Prevention. other hsa-mir-635 "Carcinoma, Lung, Non-Small-Cell" 27810784 The microRNA-635 suppresses tumorigenesis in non-small cell lung cancer. other hsa-mir-17 "Carcinoma, Breast" 27811009 Penfluridol Represses Integrin Expression in Breast Cancer through Induction of Reactive Oxygen Species and Downregulation of Sp Transcription Factors. other hsa-mir-20a "Carcinoma, Breast" 27811009 Penfluridol Represses Integrin Expression in Breast Cancer through Induction of Reactive Oxygen Species and Downregulation of Sp Transcription Factors. other hsa-mir-27a "Carcinoma, Breast" 27811009 Penfluridol Represses Integrin Expression in Breast Cancer through Induction of Reactive Oxygen Species and Downregulation of Sp Transcription Factors. other hsa-mir-129b "Carcinoma, Lung" 27813559 miR-129b suppresses cell proliferation in the human lung cancer cell lines A549 and H1299. other hsa-mir-320 Melanoma 27816966 "HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation." other hsa-mir-155 Biliary Atresia 27817193 Effect of microRNA-155 on the interferon-gamma signaling pathway in biliary atresia. other hsa-mir-3658 "Carcinoma, Bladder" 27820650 Upregulation of miR-3658 in bladder cancer and tumor progression. other hsa-let-7 "Carcinoma, Hepatocellular" 27821157 Let-7 inhibits self-renewal of hepatocellular cancer stem-like cells through regulating the epithelial-mesenchymal transition and the Wnt signaling pathway. other hsa-mir-196b Glioma 27821299 Biomarkers related with seizure risk in glioma patients: A systematic review. other hsa-mir-21 "Colitis, Ulcerative" 27824649 Downregulation of MicroRNA-21 in Colonic CD3+ T Cells in UC Remission. other hsa-mir-126 Acute Brucellosis 27824867 MicroRNA Expression Patterns of CD8+ T Cells in Acute and Chronic Brucellosis. other hsa-mir-4753 Acute Brucellosis 27824867 MicroRNA Expression Patterns of CD8+ T Cells in Acute and Chronic Brucellosis. other hsa-mir-126 White Spot Syndrome Virus Infection 27825947 Characterization of microRNAs by deep sequencing in red claw crayfish Cherax quadricarinatus haematopoietic tissue cells after white spot syndrome virus infection. other hsa-mir-184 White Spot Syndrome Virus Infection 27825947 Characterization of microRNAs by deep sequencing in red claw crayfish Cherax quadricarinatus haematopoietic tissue cells after white spot syndrome virus infection. other hsa-mir-7 White Spot Syndrome Virus Infection 27825947 Characterization of microRNAs by deep sequencing in red claw crayfish Cherax quadricarinatus haematopoietic tissue cells after white spot syndrome virus infection. other hsa-mir-206 Chondrosarcoma 27826039 Amphiregulin enhances VEGF-A production in human chondrosarcoma cells and promotes angiogenesis by inhibiting miR-206 via FAK/c-Src/PKC¦Ä pathway. other hsa-mir-93 "Carcinoma, Endometrial" 27829043 MicroRNA-93 Promotes Epithelial-Mesenchymal Transition of Endometrial Carcinoma Cells. other hsa-mir-155 Stroke 27829437 In vivo inhibition of miR-155 significantly alters post-stroke inflammatory response. other hsa-mir-19a Myeloma 27830963 MicroRNA-19a functions as an oncogene by regulating PTEN/AKT/pAKT pathway in myeloma. other hsa-mir-20b Myasthenia Gravis 27833920 miR-20b Inhibits T Cell Proliferation and Activation via NFAT Signaling Pathway in Thymoma-Associated Myasthenia Gravis. other hsa-mir-125b Atherosclerosis 27835742 Silencing of CD40 in?vivo reduces progression of experimental atherogenesis through an NF-¦ÊB/miR-125b axis and reveals new potential mediators in the pathogenesis of atherosclerosis. other hsa-mir-21 "Carcinoma, Breast" 27836600 A novel method for sensitive microRNA detection: Electropolymerization based doping. other hsa-mir-221 Glioblastoma 27837435 Exosomal miR-221 targets DNM3 to induce tumor progression and temozolomide resistance in glioma. other hsa-mir-200 Neoplasms [unspecific] 27837593 the full role of the miR-200 family in cancer progression and metastasis is not completely understood and seems to differ between different tumour types and different cellular backgrounds other hsa-mir-152 "Carcinoma, Nasopharyngeal" 27840403 MicroRNA-152 Targets Phosphatase and Tensin Homolog to Inhibit Apoptosis and Promote Cell Migration of Nasopharyngeal Carcinoma Cells. other hsa-mir-637 Glioma 27840895 Sevoflurane inhibits the migration and invasion of glioma cells by upregulating microRNA-637. other hsa-mir-25 "Carcinoma, Hepatocellular" 27840896 Knockdown of miR-25 increases the sensitivity of liver cancer stem cells to TRAIL-induced apoptosis via PTEN/PI3K/Akt/Bad signaling pathway. other hsa-mir-93 "Carcinoma, Breast, Triple Negative" 27840899 miR-93 inhibits the invasive potential of triple-negative breast cancer cells in vitro via protein kinase WNK1. other hsa-mir-21 "Carcinoma, Ovarian" 27840916 Effects of celastrol on enhancing apoptosis of ovarian cancer cells via the downregulation of microRNA?21 and the suppression of the PI3K/Akt?NF?¦ÊB signaling pathway in an in?vitro model of ovarian carcinoma. other hsa-mir-214 Osteosarcoma 27840941 Deregulated WWOX is involved in a negative feedback loop with microRNA-214-3p in osteosarcoma. other hsa-mir-302a "Carcinoma, Colon" 27840990 MicroRNA-302a enhances 5-fluorouracil-induced cell death in human colon cancer cells. other hsa-mir-208b Hepatitis [unspecific] 27841874 Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling. other hsa-mir-499a Hepatitis [unspecific] 27841874 Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling. other hsa-mir-135a Parkinson Disease 27842305 Involvement of microRNA-135a-5p in the Protective Effects of Hydrogen Sulfide Against Parkinson's Disease. other hsa-mir-375 Neoplasms [unspecific] 27844328 Molecular Profiling of Thymoma and Thymic Carcinoma: Genetic Differences and Potential Novel Therapeutic Targets. other hsa-mir-122 "Carcinoma, Hepatocellular" 27846390 ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5. other hsa-mir-210 Spinal Cord Injuries 27847197 Synchrotron radiation micro-CT as a novel tool to evaluate the effect of agomir-210 in a rat spinal cord injury model. other hsa-mir-29b Melanoma 27852308 Systems analysis identifies miR-29b regulation of invasiveness in melanoma. other hsa-mir-219 Liver Cirrhosis 27855391 Suppression of MicroRNA-219-5p Activates Keratinocyte Growth Factor to Mitigate Severity of Experimental Cirrhosis. other hsa-mir-34a Diabetic Nephropathy 27858840 Regulation of podocyte lesions in diabetic nephropathy via miR-34a in the Notch signaling pathway. other hsa-mir-148a "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 27859417 RUNX3 inhibits laryngeal squamous cell carcinoma malignancy under the regulation of miR-148a-3p/DNMT1 axis. other hsa-mir-455 Colon Neoplasms 27861461 MicroRNA-455-3p Inhibits Tumor Cell Proliferation and Induces Apoptosis in HCT116 Human Colon Cancer Cells. other hsa-let-7 Hemoglobin Diseases 27861570 HMGA2 Moderately Increases Fetal Hemoglobin Expression in Human Adult Erythroblasts. other hsa-mir-375 "Adenocarcinoma, Pancreatic Ductal" 27862697 ZFP36L2 promotes cancer cell aggressiveness and is regulated by antitumor microRNA-375 in pancreatic ductal adenocarcinoma. other hsa-mir-139 "Carcinoma, Breast" 27864119 Role of miR-139 as a surrogate marker for tumor aggression in breast cancer. other hsa-mir-146a Wound Inflammation 27864711 Mesenchymal stem cells-derived exosomal microRNAs contribute to wound inflammation. other hsa-mir-181 Wound Inflammation 27864711 Mesenchymal stem cells-derived exosomal microRNAs contribute to wound inflammation. other hsa-mir-21 Wound Inflammation 27864711 Mesenchymal stem cells-derived exosomal microRNAs contribute to wound inflammation. other hsa-mir-124 Hematologic Neoplasms 27864740 Expression Levels of Warburg-Effect Related microRNAs Correlate with each Other and that of Histone Deacetylase Enzymes in Adult Hematological Malignancies with Emphasis on Acute Myeloid Leukemia. other hsa-mir-125b Hematologic Neoplasms 27864740 Expression Levels of Warburg-Effect Related microRNAs Correlate with each Other and that of Histone Deacetylase Enzymes in Adult Hematological Malignancies with Emphasis on Acute Myeloid Leukemia. other hsa-mir-155 Hematologic Neoplasms 27864740 Expression Levels of Warburg-Effect Related microRNAs Correlate with each Other and that of Histone Deacetylase Enzymes in Adult Hematological Malignancies with Emphasis on Acute Myeloid Leukemia. other hsa-mir-23b Hematologic Neoplasms 27864740 Expression Levels of Warburg-Effect Related microRNAs Correlate with each Other and that of Histone Deacetylase Enzymes in Adult Hematological Malignancies with Emphasis on Acute Myeloid Leukemia. other hsa-mir-26a Hematologic Neoplasms 27864740 Expression Levels of Warburg-Effect Related microRNAs Correlate with each Other and that of Histone Deacetylase Enzymes in Adult Hematological Malignancies with Emphasis on Acute Myeloid Leukemia. other hsa-mir-378 Hematologic Neoplasms 27864740 Expression Levels of Warburg-Effect Related microRNAs Correlate with each Other and that of Histone Deacetylase Enzymes in Adult Hematological Malignancies with Emphasis on Acute Myeloid Leukemia. other hsa-mir-708 Bipolar Disorder 27864917 Genetic variation in the miR-708 gene and its binding targets in bipolar disorder. other hsa-mir-182 Acute Kidney Failure 27865759 miRNA-Coordinated Networks as Promising Therapeutic Targets for Acute Kidney Injury. other hsa-mir-126 "Cardiomyopathy, Ischemic" 27866054 Comparison of miRNA signature versus conventional biomarkers before and after off-pump coronary artery bypass graft. other hsa-mir-155 "Cardiomyopathy, Ischemic" 27866054 Comparison of miRNA signature versus conventional biomarkers before and after off-pump coronary artery bypass graft. other hsa-mir-499 "Cardiomyopathy, Ischemic" 27866054 Comparison of miRNA signature versus conventional biomarkers before and after off-pump coronary artery bypass graft. other hsa-mir-502 "Carcinoma, Gastric" 27866197 Rs56288038 (C/G) in 3'UTR of IRF-1 Regulated by MiR-502-5p Promotes Gastric Cancer Development. other hsa-mir-188 Azoospermia 27868267 Reduced microRNA-188-3p expression contributes to apoptosis of spermatogenic cells in patients with azoospermia. other hsa-mir-192 Ischemia-Reperfusion Injury 27870736 Lidocaine Administration Controls MicroRNAs Alterations Observed After Lung Ischemia-Reperfusion Injury. other hsa-mir-182 Kidney Injury 27870928 miR-182-5p Inhibition Ameliorates Ischemic Acute Kidney Injury. other hsa-mir-326 Glioblastoma 27871300 PI3 kinase pathway regulated miRNome in glioblastoma: identification of miR-326 as a tumour suppressor miRNA. other hsa-let-7 "Carcinoma, Laryngeal" 27874955 Expression and significances of MiRNA Let-7 and HMGA2 in laryngeal carcinoma. other hsa-mir-30a "Carcinoma, Gastric" 27876712 MiR-30a Decreases Multidrug Resistance (MDR) of Gastric Cancer Cells. other hsa-mir-590 "Carcinoma, Colon" 27878255 Roles of mitochondrial transcription factor A and microRNA?590?3p in the development of colon cancer. other hsa-mir-20b "Carcinoma, Colon" 27878272 miR-20b reduces 5-FU resistance by suppressing the ADAM9/EGFR signaling pathway in colon cancer. other hsa-mir-375 "Squamous Cell Carcinoma, Tongue" 27878285 Trichostatin A increases radiosensitization of tongue squamous cell carcinoma via miR?375. other hsa-mir-148a Obesity 27878286 Obesity?associated miR?148a is regulated by cytokines and adipokines via a transcriptional mechanism. other hsa-mir-196a Lung Neoplasms 27880728 Analysis of miRNA profiles identified miR-196a as a crucial mediator of aberrant PI3K/AKT signaling in lung cancer cells. other hsa-mir-21 "Carcinoma, Esophageal" 27885434 Evaluation of miR-21 and miR-375 as prognostic biomarkers in oesophageal cancer in high-risk areas in China. other hsa-mir-375 "Carcinoma, Esophageal" 27885434 Evaluation of miR-21 and miR-375 as prognostic biomarkers in oesophageal cancer in high-risk areas in China. other hsa-mir-99 Hepatitis B Virus Infection 27886437 The microRNA-99 family modulates hepatitis B virus replication by promoting IGF-1R/PI3K/Akt/mTOR/ULK1 signaling-induced autophagy. other hsa-mir-18a Leukemia 27888798 miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis. other hsa-mir-20a Leukemia 27888798 miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis. other hsa-mir-124 "Squamous Cell Carcinoma, Oral" 27889233 Icaritin induces mitochondrial apoptosis by up-regulating miR-124 in human oral squamous cell carcinoma cells. other hsa-mir-616 "Carcinoma, Lung" 27890917 Sulforaphane suppresses EMT and metastasis in human lung cancer through miR-616-5p-mediated GSK3¦Â/¦Â-catenin signaling pathways. other hsa-mir-338 Schizophrenia 27892953 Thalamic miR-338-3p mediates auditory thalamocortical disruption and its late onset in models of 22q11.2 microdeletion. other hsa-mir-128 Glioblastoma 27893811 The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death. other hsa-mir-30b "Carcinoma, Hepatocellular" 27894814 Tanshinone IIA induced cell death via miR30b-p53-PTPN11/SHP2 signaling pathway in human hepatocellular carcinoma cells. other hsa-mir-142 Wound Healing 27894934 MiR-142 Is Required for Staphylococcus aureus Clearance at Skin Wound Sites via Small GTPase-Mediated Regulation of the Neutrophil Actin Cytoskeleton. other hsa-mir-210 Atherosclerosis 27895035 MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions. other hsa-mir-122 "Carcinoma, Hepatocellular" 27895094 Crosstalk between microRNA-122 and FOX family genes in HepG2 cells. other hsa-mir-18a Neuroblastoma 27895778 Regulatory network analysis of genes and microRNAs in human hepatoblastoma. other hsa-mir-21 Leukemia 27895788 Effects of microRNA-21 on the biological functions of T-cell acute lymphoblastic lymphoma/leukemia. other hsa-mir-451 Esophageal Neoplasms 27896643 A novel signaling role for miR-451 in esophageal tumor microenvironment and its contribution to tumor progression. other hsa-mir-122 "Diabetes Mellitus, Type 2" 27899485 Circulating MicroRNA-122 Is Associated With the Risk of New-Onset Metabolic Syndrome and Type 2 Diabetes. other hsa-mir-150 Leukemia 27899822 miR-150 exerts antileukemia activity in vitro and in vivo through regulating genes in multiple pathways. other hsa-mir-152 Leiomyosarcoma 27900663 miR-152 down-regulation is associated with MET up-regulation in leiomyosarcoma and undifferentiated pleomorphic sarcoma. other hsa-mir-31 "Carcinoma, Gastric" 27904131 MiR-31 Regulates Rho-Associated Kinase-Myosin Light Chain (ROCK-MLC) Pathway and Inhibits Gastric Cancer Invasion other hsa-mir-221 "Carcinoma, Hepatocellular" 27904678 miR-221 promotes growth and invasion of hepatocellular carcinoma cells by constitutive activation of NF¦ÊB. other hsa-mir-128 Cerebral Ischemia 27905005 MicroRNA-128-3p Protects Mouse Against Cerebral Ischemia Through Reducing p38¦Á Mitogen-Activated Protein Kinase Activity. other hsa-mir-26a "Carcinoma, Hepatocellular" 27906498 "Sialyltransferase ST3GAL6 mediates the effect of microRNA-26a on cell growth, migration, and invasion in hepatocellular carcinoma through the protein kinase B/mammalian target of rapamycin pathway." other hsa-mir-144 "Diabetes Mellitus, Type 2" 27906902 Comparison of Transcriptome Between Type 2 Diabetes Mellitus and Impaired Fasting Glucose. other hsa-mir-192 "Diabetes Mellitus, Type 2" 27906902 Comparison of Transcriptome Between Type 2 Diabetes Mellitus and Impaired Fasting Glucose. other hsa-mir-29a "Diabetes Mellitus, Type 2" 27906902 Comparison of Transcriptome Between Type 2 Diabetes Mellitus and Impaired Fasting Glucose. other hsa-mir-145 Spinal Cord Injuries 27907012 The Signature of MicroRNA Dysregulation in Muscle Paralyzed by Spinal Cord Injury Includes Downregulation of MicroRNAs that Target Myostatin Signaling. other hsa-mir-23a Spinal Cord Injuries 27907012 The Signature of MicroRNA Dysregulation in Muscle Paralyzed by Spinal Cord Injury Includes Downregulation of MicroRNAs that Target Myostatin Signaling. other hsa-mir-21 Glioma 27909726 MicroRNA?21 promotes migration and invasion of glioma cells via activation of Sox2 and ¦Â?catenin signaling. other hsa-mir-181a Vascular Disease [unspecific] 27911586 miRNA-181a/b Regulates Phenotypes of Vessel Smooth Muscle Cells Through Serum Response Factor. other hsa-mir-181b Vascular Disease [unspecific] 27911586 miRNA-181a/b Regulates Phenotypes of Vessel Smooth Muscle Cells Through Serum Response Factor. other hsa-mir-98 Inflammation 27913008 MicroRNA-98 plays a critical role in experimental myocarditis. other hsa-mir-155 "Carcinoma, Hepatocellular" 27913196 NF-kB-regulated exosomal miR-155 promotes the inflammation associated with arsenite carcinogenesis. other hsa-mir-155 Adenovirus Infection 27916071 The effect of curcumin on the expression of miR-155 to apoptosis and invasion of extravillus trophoblast cells treated by lipopolysaccharide. other hsa-mir-34a Pain 27917453 "Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors." other hsa-mir-200c Colorectal Carcinoma 27918105 "Resveratrol Inhibits Proliferation, Invasion, and Epithelial-Mesenchymal Transition by Increasing miR-200c Expression in HCT-116 Colorectal Cancer Cells." other hsa-mir-497 Atherosclerosis 27918592 MicroRNA-497 Induces Apoptosis and Suppresses Proliferation via the Bcl-2/Bax-Caspase9-Caspase3 Pathway and Cyclin D2 Protein in HUVECs. other hsa-mir-7 Colorectal Carcinoma 27919977 MicroRNA-7 Is Associated with Malignant Potential and Poor Prognosis in Human Colorectal Cancer. other hsa-mir-33 Atherosclerosis 27920122 MicroRNA-33 Controls Adaptive Fibrotic Response in the Remodeling Heart by Preserving Lipid Raft Cholesterol. other hsa-mir-328 "Carcinoma, Gastric" 27923017 Expression of microRNA-328 Functions as a Biomarker for Recurrence of Early Gastric Cancer (EGC) After Endoscopic Submucosal Dissection (ESD) by Modulating CD44. other hsa-mir-126 Atherosclerosis 27923459 MicroRNAs in lipid metabolism and atherosclerosis. other hsa-mir-33a Atherosclerosis 27923459 MicroRNAs in lipid metabolism and atherosclerosis. other hsa-mir-92a Atherosclerosis 27923459 MicroRNAs in lipid metabolism and atherosclerosis. other hsa-mir-29 Cardiovascular Diseases [unspecific] 27932253 Regulation of cyclin D1 by arsenic and microRNA inhibits adipogenesis. other hsa-mir-29b Cardiovascular Diseases [unspecific] 27932253 Regulation of cyclin D1 by arsenic and microRNA inhibits adipogenesis. other hsa-mir-550a Diabetes Mellitus 27935135 Micro RNA-550a interferes with vitamin D metabolism in peripheral B cells of patients with diabetes. other hsa-mir-221 Liver Cirrhosis 27935974 Epigallocatechin-3-Gallate Upregulates miR-221 to Inhibit Osteopontin-Dependent Hepatic Fibrosis. other hsa-mir-92a Cardiovascular Diseases [unspecific] 27936205 Hyperhomocysteinemia in ApoE-/- Mice Leads to Overexpression of Enhancer of Zeste Homolog 2 via miR-92a Regulation. other hsa-mir-132 Intracerebral Hemorrhage 27940326 MicroRNA-132 attenuates neurobehavioral and neuropathological changes associated with intracerebral hemorrhage in mice. other hsa-mir-221 "Carcinoma, Breast" 27940575 mda-7/IL-24 Mediates Cancer Cell-Specific Death via Regulation of miR-221 and the Beclin-1 Axis. other hsa-mir-200 "Carcinoma, Biliary Tract" 27941621 Relevance of MicroRNA200 Family and MicroRNA205 for Epithelial to Mesenchymal Transition and Clinical Outcome in Biliary Tract Cancer Patients. other hsa-mir-205 "Carcinoma, Biliary Tract" 27941621 Relevance of MicroRNA200 Family and MicroRNA205 for Epithelial to Mesenchymal Transition and Clinical Outcome in Biliary Tract Cancer Patients. other hsa-mir-142 Autoimmune Diseases [unspecific] 27943367 Analysis of miR-146a and miR-142-3p as Potential Markers of Freshly Isolated or In Vitro-Expanded Human Treg cells. other hsa-mir-146a Autoimmune Diseases [unspecific] 27943367 Analysis of miR-146a and miR-142-3p as Potential Markers of Freshly Isolated or In Vitro-Expanded Human Treg cells. other hsa-mir-145 "Aortic Aneurysm, Abdominal" 27956160 MicroRNA-145 Mediates the Formation of Angiotensin II-Induced Murine Abdominal Aortic Aneurysm. other hsa-mir-1271 Multiple Myeloma 27959416 MicroRNA-1271 inhibits proliferation and promotes apoptosis of multiple myeloma cells through inhibiting smoothened-mediated Hedgehog signaling pathway. other hsa-mir-376c Gastric Neoplasms 27965982 hsa-miR-376c-3p Regulates Gastric Tumor Growth Both In Vitro and In Vivo. other hsa-mir-205 "Squamous Cell Carcinoma, Esophageal" 27974696 Sp1-mediated transcriptional activation of miR-205 promotes radioresistance in esophageal squamous cell carcinoma. other hsa-mir-9 Glioma 27975329 Density-Dependent Regulation of Glioma Cell Proliferation and Invasion Mediated by miR-9. other hsa-mir-34a Diabetic Retinopathy 27977785 LGR4 Is a Direct Target of MicroRNA-34a and Modulates the Proliferation and Migration of Retinal Pigment Epithelial ARPE-19 Cells. other hsa-mir-376a "Carcinoma, Ovarian" 27979415 MiR-376a promotion of proliferation and metastases in ovarian cancer other hsa-mir-122 "Carcinoma, Hepatocellular" 27980102 Blocking the CCL2-CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model. other hsa-mir-155 Inflammation 27981414 MicroRNA-155: a Novel Armamentarium Against Inflammatory Diseases. other hsa-mir-760 "Carcinoma, Breast" 27981531 miR-760 mediates chemoresistance through inhibition of epithelial mesenchymal transition in breast cancer cells. other hsa-mir-155 Human Immunodeficiency Virus Infection 27981723 MicroRNA-155 is a biomarker of T-cell activation and immune dysfunction in HIV-1-infected patients. other hsa-mir-125a "Carcinoma, Hepatocellular" 27982429 MicroRNA-125a-5p Is a Downstream Effector of Sorafenib in Its Antiproliferative Activity Toward Human Hepatocellular Carcinoma Cells. other hsa-mir-221 "Carcinoma, Hepatocellular" 27983537 Clinical potential of miRNA-221 as a novel prognostic biomarker for hepatocellular carcinoma. other hsa-mir-210 Inflammation 27983913 Precise Regulation of miR-210 Is Critical for the Cellular Homeostasis Maintenance and Transplantation Efficacy Enhancement of Mesenchymal Stem Cells in Acute Liver Failure Therapy. other hsa-mir-9 Rhabdomyosarcoma 27984116 MicroRNA and gene co-expression networks characterize biological and clinical behavior of rhabdomyosarcomas. other hsa-mir-29a "Carcinoma, Breast" 27986463 Tamoxifen differentially regulates miR-29b-1 and miR-29a expression depending on endocrine-sensitivity in breast cancer cells. other hsa-mir-29b "Carcinoma, Breast" 27986463 Tamoxifen differentially regulates miR-29b-1 and miR-29a expression depending on endocrine-sensitivity in breast cancer cells. other hsa-mir-101 "Carcinoma, Pancreatic" 27988337 micorRNA-101 silences DNA-PKcs and sensitizes pancreatic cancer cells to gemcitabine. other hsa-mir-125b Osteosarcoma 27990096 miR-125b and miR-100 Are Predictive Biomarkers of Response to Induction Chemotherapy in Osteosarcoma. other hsa-mir-21 Neoplasms [unspecific] 27992999 Systematic Evaluation of Biophysical and Functional Characteristics of Selenomethylene-Locked Nucleic Acid-Mediated Inhibition of miR-21. other hsa-mir-601 "Carcinoma, Pancreatic" 27993677 Identification of miR-601 as a novel regulator in the development of pancreatic cancer. other hsa-mir-196a-2 Behcet Disease 27993883 Association of Reduced Heme Oxygenase-1 with Decreased MicroRNA-196a2 Expression in Peripheral Blood Mononuclear Cells of Patients with Intestinal Behcet's Disease. other hsa-mir-34c Human Immunodeficiency Virus Infection 27993935 miRNA profiling of human naive CD4 T cells links miR-34c-5p to cell activation and HIV replication. other hsa-mir-206 Coronary Artery Disease 27994218 MiR-206 Suppresses the Progression of Coronary Artery Disease by Modulating Vascular Endothelial Growth Factor (VEGF) Expression. other hsa-mir-21 Leukemia 27995885 Targeted suppression of miRNA-21 inhibit K562 cells growth through PTEN-PI3K/AKT signaling pathway. other hsa-mir-1 Viral Myocarditis 27997912 "Analysis of the Indicating Value of Cardiac Troponin I, Tumor Necrosis Factor-¦Á, Interleukin-18, Mir-1 and Mir-146b for Viral Myocarditis among Children." other hsa-mir-146b Viral Myocarditis 27997912 "Analysis of the Indicating Value of Cardiac Troponin I, Tumor Necrosis Factor-¦Á, Interleukin-18, Mir-1 and Mir-146b for Viral Myocarditis among Children." other hsa-mir-223 "Carcinoma, Hepatocellular" 27998765 MiR-223 modulates hepatocellular carcinoma cell proliferation through promoting apoptosis via the Rab1-mediated mTOR activation. other hsa-mir-146a Inflammation 27998828 "we reported an anti-inflammatory effect of resveratrol and hydroxytyrosol at low, nutritionally relevant concentrations, involving the inhibition of granulocytes and monocytes activation, the modulation of miR-146a expression and the activation of Nrf2" other hsa-mir-223 Inflammation 27999792 Inflammation Related MicroRNAs Are Modulated in Total Plasma and in Extracellular Vesicles from Rats with Chronic Ingestion of Sucrose. other hsa-mir-22 Malignant Neoplasms [unspecific] 28000852 Molecular mechanisms and clinical applications of miR-22 in regulating malignant progression in human cancer other hsa-mir-27a "Carcinoma, Thyroid" 28002594 "Effects of miR-27a upregulation on thyroid cancer cells migration, invasion, and angiogenesis." other hsa-mir-200c "Carcinoma, Breast" 28003747 MicroRNA-200c delivered by solid lipid nanoparticles enhances the effect of paclitaxel on breast cancer stem cell. other hsa-let-7 Neoplasms [unspecific] 28004230 "In Silico Mining of Conserved miRNAs of Indian Catfish Clarias batrachus (Linnaeus, 1758) from the Contigs, ESTs, and BAC End Sequences." other hsa-mir-133 Neoplasms [unspecific] 28004230 "In Silico Mining of Conserved miRNAs of Indian Catfish Clarias batrachus (Linnaeus, 1758) from the Contigs, ESTs, and BAC End Sequences." other hsa-mir-137 Neoplasms [unspecific] 28004230 "In Silico Mining of Conserved miRNAs of Indian Catfish Clarias batrachus (Linnaeus, 1758) from the Contigs, ESTs, and BAC End Sequences." other hsa-mir-455 Neoplasms [unspecific] 28004230 "In Silico Mining of Conserved miRNAs of Indian Catfish Clarias batrachus (Linnaeus, 1758) from the Contigs, ESTs, and BAC End Sequences." other hsa-mir-140 "Adenocarcinoma, Lung" 28005074 MiR-206 and miR-140 also suppressed lung adenocarcinoma cell metastasis in vitro and in vivo by regulating EMT-related factors other hsa-mir-206 "Adenocarcinoma, Lung" 28005074 MiR-206 and miR-140 also suppressed lung adenocarcinoma cell metastasis in vitro and in vivo by regulating EMT-related factors other hsa-mir-4286 Melanoma 28005927 Antiproliferative and Pro-Apoptotic Effects of MiR-4286 Inhibition in Melanoma Cells. other hsa-mir-371 "Carcinoma, Prostate" 28005952 MicroRNA and Transcription Factor Gene Regulatory Network Analysis Reveals Key Regulatory Elements Associated with Prostate Cancer Progression. other hsa-mir-512 "Carcinoma, Prostate" 28005952 MicroRNA and Transcription Factor Gene Regulatory Network Analysis Reveals Key Regulatory Elements Associated with Prostate Cancer Progression. other hsa-mir-663 "Carcinoma, Prostate" 28005952 MicroRNA and Transcription Factor Gene Regulatory Network Analysis Reveals Key Regulatory Elements Associated with Prostate Cancer Progression. other hsa-mir-665 "Carcinoma, Prostate" 28005952 MicroRNA and Transcription Factor Gene Regulatory Network Analysis Reveals Key Regulatory Elements Associated with Prostate Cancer Progression. other hsa-mir-671 "Carcinoma, Prostate" 28005952 MicroRNA and Transcription Factor Gene Regulatory Network Analysis Reveals Key Regulatory Elements Associated with Prostate Cancer Progression. other hsa-mir-21 Sepsis 28006751 miR-375 ameliorates sepsis by downregulating miR-21 level via inhibiting JAK2-STAT3 signaling. other hsa-mir-375 Sepsis 28006751 miR-375 ameliorates sepsis by downregulating miR-21 level via inhibiting JAK2-STAT3 signaling. other hsa-mir-215 Colorectal Carcinoma 28006930 Systemic administration of miRNA mimics by liposomal delivery system in animal model of colorectal carcinoma. other hsa-mir-335 "Carcinoma, Breast" 28008602 MicroRNA-335-5p and -3p synergize to inhibit estrogen receptor alpha expression and promote tamoxifen resistance. other hsa-mir-122 Chronic Hepatitis C 28008821 Cooperative enhancement of translation by two adjacent microRNA-122/Argonaute 2 complexes binding to the 5' untranslated region of hepatitis C virus RNA. other hsa-let-7a "Carcinoma, Hepatocellular" 28012864 Germline and somatic DICER1 mutations in familial and sporadic liver tumors. other hsa-mir-205 "Squamous Cell Carcinoma, Skin or Unspecific" 28013372 MiR-21 and miR-205 are induced in invasive cutaneous squamous cell carcinomas. other hsa-mir-21 "Squamous Cell Carcinoma, Skin or Unspecific" 28013372 MiR-21 and miR-205 are induced in invasive cutaneous squamous cell carcinomas. other hsa-mir-155 Cardiovascular Diseases [unspecific] 28018919 a recent clinical trial of Miravirsen targeting microRNA-122 sheds light on exploiting microRNA-155 as a novel target to develop effective therapeutic strategies for cardiovascular diseases in the near future other hsa-mir-124 Myelodysplastic Syndromes 28024498 Reactivated Expression of MicroRNA-124 in Patients with Myelodysplastic Syndromes after Demethylating Therapy. other hsa-mir-218 Gastrointestinal Neoplasms 28024574 miRNA-218-loaded carboxymethyl chitosan - Tocopherol nanoparticle to suppress the proliferation of gastrointestinal stromal tumor growth. other hsa-mir-155 Stroke 28025572 Influence of miR-155 on Cell Apoptosis in Rats with Ischemic Stroke: Role of the Ras Homolog Enriched in Brain (Rheb)/mTOR Pathway. other hsa-mir-200a Liver Cirrhosis 28025657 miR-200a controls hepatic stellate cell activation and fibrosis via SIRT1/Notch1 signal pathway. other hsa-mir-1 Chronic Obstructive Pulmonary Disease 28025995 Prediction of key genes and miRNAs responsible for loss of muscle force in patients during an acute exacerbation of chronic obstructive pulmonary disease. other hsa-mir-15a Chronic Obstructive Pulmonary Disease 28025995 Prediction of key genes and miRNAs responsible for loss of muscle force in patients during an acute exacerbation of chronic obstructive pulmonary disease. other hsa-mir-16 Chronic Obstructive Pulmonary Disease 28025995 Prediction of key genes and miRNAs responsible for loss of muscle force in patients during an acute exacerbation of chronic obstructive pulmonary disease. other hsa-mir-23a Chronic Obstructive Pulmonary Disease 28025995 Prediction of key genes and miRNAs responsible for loss of muscle force in patients during an acute exacerbation of chronic obstructive pulmonary disease. other hsa-mir-9 Chronic Obstructive Pulmonary Disease 28025995 Prediction of key genes and miRNAs responsible for loss of muscle force in patients during an acute exacerbation of chronic obstructive pulmonary disease. other hsa-mir-200a "Carcinoma, Esophageal" 28025999 miR-200a-3p promotes the proliferation of human esophageal cancer cells by post-transcriptionally regulating cytoplasmic collapsin response mediator protein-1. other hsa-mir-9 Infection [unspecific] 28031262 Pseudomonas aeruginosa GroEL Stimulates Production of PTX3 by Activating the NF-¦ÊB Pathway and Simultaneously Downregulating MicroRNA-9. other hsa-mir-15 Malignant Neoplasms [unspecific] 28032148 The relationship between platinum drug resistance and epithelial-mesenchymal transition. other hsa-mir-186 Malignant Neoplasms [unspecific] 28032148 The relationship between platinum drug resistance and epithelial-mesenchymal transition. other hsa-mir-210 Osteosarcoma 28032372 MicroRNA-210 is increased and it is required for dedifferentiation of osteosarcoma cell line. other hsa-mir-192 Ischemia-Reperfusion Injury 28035621 Implications of dynamic changes in miR-192 expression in ischemic acute kidney injury. other hsa-mir-210 Neoplasms [unspecific] 28036268 "Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate." other hsa-mir-143 Neoplasms [unspecific] 28038917 A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells. other hsa-mir-21 Systemic Lupus Erythematosus 28039018 Estrogen-regulated STAT1 activation promotes TLR8 expression to facilitate signaling via microRNA-21 in systemic lupus erythematosus. other hsa-mir-192 Glioma 28039611 Alternative new mesenchymal stem cell source exerts tumor tropism through ALCAM and N-cadherin via regulation of microRNA-192 and -218. other hsa-mir-218 Glioma 28039611 Alternative new mesenchymal stem cell source exerts tumor tropism through ALCAM and N-cadherin via regulation of microRNA-192 and -218. other hsa-mir-1 "Leukemia, Myeloid, Acute" 28042875 "the PI3K/mTOR dual inhibitor BEZ235 effectively chemosensitizes AML cells via increasing miR-1-3p and subsequently down-regulating BAG4, EDN1 and ABCB1" other hsa-mir-31 "Carcinoma, Nasopharyngeal" 28042945 Minicircle-oriP-miR-31 as a Novel EBNA1-Specific miRNA Therapy Approach for Nasopharyngeal Carcinoma. other hsa-mir-190b "Carcinoma, Gastric" 28044223 MicroRNA-190b confers radio-sensitivity through negative regulation of Bcl-2 in gastric cancer cells. other hsa-mir-34a "Carcinoma, Renal Cell" 28045889 Metformin Induces Growth Inhibition and Cell Cycle Arrest by Upregulating MicroRNA34a in Renal Cancer Cells. other hsa-mir-182 Inflammation 28045967 Induction of Multiple miR-200/182 Members in the Brains of Mice Are Associated with Acute Herpes Simplex Virus 1 Encephalitis. other hsa-mir-183 Inflammation 28045967 Induction of Multiple miR-200/182 Members in the Brains of Mice Are Associated with Acute Herpes Simplex Virus 1 Encephalitis. other hsa-mir-210 Neoplasms [unspecific] 28046107 RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature. other hsa-mir-214 "Carcinoma, Breast" 28051254 MiR-214 negatively regulates proliferation and WNT/¦Â-catenin signaling in breast cancer. other hsa-mir-361 "Carcinoma, Lung, Non-Small-Cell" 28051257 Downregulation of miR-361-5p associates with aggressive clinicopathological features and unfavorable prognosis in non-small cell lung cancer. other hsa-mir-379 "Carcinoma, Hepatocellular" 28051262 Bioinformatic identification of IGF1 as a hub gene in hepatocellular carcinoma (HCC) and in-vitro analysis of the chemosensitizing effect of miR-379 via suppressing the IGF1/IGF1R signaling pathway. other hsa-mir-125a "Leukemia, Myeloid, Acute" 28053194 miR-125b promotes MLL-AF9-driven murine acute myeloid leukemia involving a VEGFA-mediated non-cell-intrinsic mechanism. other hsa-mir-125b "Leukemia, Myeloid, Acute" 28053194 miR-125b promotes MLL-AF9-driven murine acute myeloid leukemia involving a VEGFA-mediated non-cell-intrinsic mechanism. other hsa-mir-378 Renal Fibrosis 28053239 miR-378 reduces mesangial hypertrophy and kidney tubular fibrosis via MAPK signalling. other hsa-mir-181a Chronic Hepatitis B 28053323 HBx promotes cell proliferation by disturbing the cross-talk between miR-181a and PTEN. other hsa-mir-1292 Colorectal Carcinoma 28054337 Combined miRNA profiling and proteomics demonstrates that different miRNAs target a common set of proteins to promote colorectal cancer metastasis. other hsa-mir-424 Colorectal Carcinoma 28054337 Combined miRNA profiling and proteomics demonstrates that different miRNAs target a common set of proteins to promote colorectal cancer metastasis. other hsa-mir-503 Colorectal Carcinoma 28054337 Combined miRNA profiling and proteomics demonstrates that different miRNAs target a common set of proteins to promote colorectal cancer metastasis. other hsa-mir-124 Ewing Sarcoma 28055964 miR-124 represses the mesenchymal features and suppresses metastasis in Ewing sarcoma. other hsa-mir-504 Glioblastoma 28056026 "Integration of MicroRNA, mRNA, and Protein Expression Data for the Identification of Cancer-Related MicroRNAs." other hsa-mir-152 "Carcinoma, Gastric" 28056089 Helicobacter Pylori Promote B7-H1 Expression by Suppressing miR-152 and miR-200b in Gastric Cancer Cells. other hsa-mir-200b "Carcinoma, Gastric" 28056089 Helicobacter Pylori Promote B7-H1 Expression by Suppressing miR-152 and miR-200b in Gastric Cancer Cells. other hsa-mir-497 "Adenocarcinoma, Lung" 28057758 Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells. other hsa-mir-340 "Carcinoma, Gastric" 28057912 "miR-340 Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cell Line SGC-7901, Possibly via the AKT Pathway." other hsa-let-7b Myocardial Infarction 28062497 Increased Proangiogenic Activity of Mobilized CD34+ Progenitor Cells of Patients With Acute ST-Segment-Elevation Myocardial Infarction: Role of Differential MicroRNA-378 Expression. other hsa-mir-378 Myocardial Infarction 28062497 Increased Proangiogenic Activity of Mobilized CD34+ Progenitor Cells of Patients With Acute ST-Segment-Elevation Myocardial Infarction: Role of Differential MicroRNA-378 Expression. other hsa-mir-9 "Carcinoma, Hepatocellular" 28062574 Loss of N-Acetylgalactosaminyltransferase-4 Orchestrates Oncogenic MicroRNA-9 in Hepatocellular Carcinoma. other hsa-mir-181b "Adenocarcinoma, Pancreatic Ductal" 28064436 "MicroRNA-181b-5p, ETS1, and the c-Met pathway exacerbate the prognosis of pancreatic ductal adenocarcinoma after radiation therapy." other hsa-mir-192 Lung Neoplasms 28067164 "pharmacological effects of curcumin in lung cancer are also mediated by modulation of several miRNAs, such as downregulation of oncogenic miR-21 and upregulation of oncosuppressive miR-192-5p and miR-215" other hsa-mir-21 Lung Neoplasms 28067164 "pharmacological effects of curcumin in lung cancer are also mediated by modulation of several miRNAs, such as downregulation of oncogenic miR-21 and upregulation of oncosuppressive miR-192-5p and miR-215" other hsa-mir-215 Lung Neoplasms 28067164 "pharmacological effects of curcumin in lung cancer are also mediated by modulation of several miRNAs, such as downregulation of oncogenic miR-21 and upregulation of oncosuppressive miR-192-5p and miR-215" other hsa-mir-122 Chronic Hepatitis C 28067225 Hepatitis C virus has a genetically determined lymphotropism through co-receptor B7.2. other hsa-mir-16 "Carcinoma, Ovarian" 28067383 The functional consequences and prognostic value of dosage sensitivity in ovarian cancer. other hsa-mir-98 "Carcinoma, Ovarian" 28067383 The functional consequences and prognostic value of dosage sensitivity in ovarian cancer. other hsa-mir-34c "Carcinoma, Breast, Triple Negative" 28069384 Regulation of cancerous progression and epithelial-mesenchymal transition by miR-34c-3p via modulation of MAP3K2 signaling in triple-negative breast cancer cells. other hsa-mir-133b "Squamous Cell Carcinoma, Esophageal" 28069586 SQLE induces epithelial-to-mesenchymal transition by regulating of miR-133b in esophageal squamous cell carcinoma. other hsa-let-7 Neoplasms [unspecific] 28070818 "Entangling Relation of Micro RNA-let7, miRNA-200 and miRNA-125 with Various Cancers." other hsa-mir-181 Leukemia 28072759 Induction of K562 Cell Apoptosis by As4S4 via Down-Regulating miR181. other hsa-mir-221 Osteosarcoma 28074104 Bufalin Inhibits Proliferation and Induces Apoptosis in Osteosarcoma Cells by Downregulating MicroRNA-221. other hsa-mir-124 "Carcinoma, Oral" 28077301 MiR-124 down-regulation is critical for cancer associated fibroblasts-enhanced tumor growth of oral carcinoma. other hsa-mir-193b Polycystic Kidney Disease 28077374 "Expression of ErbB4 in vivo was increased in human ADPKD and Pkd1 cystic kidneys, both transcriptionally and posttranscriptionally by mir-193b-3p" other hsa-mir-199a Cardiac Myocyte Injury 28077443 Single-Dose Intracardiac Injection of Pro-Regenerative MicroRNAs Improves Cardiac Function After Myocardial Infarction. other hsa-mir-19a Hepatitis C Virus Infection 28077652 "Furthermore, we demonstrate the role of exosomal miR-19a in activation of the STAT3-TGF-¦Â pathway in HSC" other hsa-mir-205 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 28078305 miR-375 and miR-205 Regulate the Invasion and Migration of Laryngeal Squamous Cell Carcinoma Synergistically via AKT-Mediated EMT. other hsa-mir-375 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 28078305 miR-375 and miR-205 Regulate the Invasion and Migration of Laryngeal Squamous Cell Carcinoma Synergistically via AKT-Mediated EMT. other hsa-mir-26a "Carcinoma, Hepatocellular" 28079894 MiR-26 enhances chemosensitivity and promotes apoptosis of hepatocellular carcinoma cells through inhibiting autophagy. other hsa-mir-92a "Carcinoma, Cervical" 28081742 MicroRNA-92a Promotes Cell Proliferation in Cervical Cancer via Inhibiting p21 Expression and Promoting Cell Cycle Progression. other hsa-mir-19a Asthma 28081849 Constitutive high expression of protein arginine methyltransferase 1 in asthmatic airway smooth muscle cells is caused by reduced microRNA-19a expression and leads to enhanced remodeling. other hsa-mir-21 Infection [unspecific] 28083515 Genome-Wide Transcriptional and Post-transcriptional Regulation of Innate Immune and Defense Responses of Bovine Mammary Gland to Staphylococcus aureus. other hsa-mir-223 Infection [unspecific] 28083515 Genome-Wide Transcriptional and Post-transcriptional Regulation of Innate Immune and Defense Responses of Bovine Mammary Gland to Staphylococcus aureus. other hsa-mir-19b Liver Diseases [unspecific] 28083843 MicroRNA-19b Expression in Human Biliary Atresia Specimens and Its Role in BA-Related Fibrosis. other hsa-mir-16 "Carcinoma, Thyroid, Papillary" 28085013 Expressions of miRNAs in papillary thyroid carcinoma and their associations with the clinical characteristics of PTC. other hsa-mir-122 Chronic Hepatitis C 28087069 "Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial." other hsa-mir-24 Cholangiocarcinoma 28087162 miR-24 Inhibition Increases Menin Expression and Decreases Cholangiocarcinoma Proliferation. other hsa-mir-143 Metabolic Syndrome 28088407 Far-off and close-up dry matter intake modulate indicators of immunometabolic adaptations to lactation in subcutaneous adipose tissue of pasture-based transition dairy cows. other hsa-mir-29c "Carcinoma, Pancreatic" 28088520 Palmitic acid increases invasiveness of pancreatic cancer cells AsPC-1 through TLR4/ROS/NF-¦ÊB/MMP-9 signaling pathway. other hsa-mir-21 "Adenocarcinoma, Lung" 28089356 Insertions and Deletions Target Lineage-Defining Genes in Human Cancers. other hsa-mir-126 "Adenocarcinoma, Prostate" 28089917 "microRNAs and DICER1 are regulated by 1,25-dihydroxyvitamin D in prostate stroma." other hsa-mir-154 "Adenocarcinoma, Prostate" 28089917 "microRNAs and DICER1 are regulated by 1,25-dihydroxyvitamin D in prostate stroma." other hsa-mir-21 "Adenocarcinoma, Prostate" 28089917 "microRNAs and DICER1 are regulated by 1,25-dihydroxyvitamin D in prostate stroma." other hsa-mir-125b Amyotrophic Lateral Sclerosis 28090150 M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b. other hsa-mir-146a Sepsis 28090688 Exosomal miR-146a Contributes to the Enhanced Therapeutic Efficacy of Interleukin-1¦Â-Primed Mesenchymal Stem Cells Against Sepsis. other hsa-mir-19b Heart Failure 28091585 MicroRNA-19b is a potential biomarker of increased myocardial collagen cross-linking in patients with aortic stenosis and heart failure. other hsa-mir-1227 Glioma 28091986 miR-1227 may be associated with increased migration and miR-32 and miR-222 with decreased migration other hsa-mir-222 Glioma 28091986 miR-1227 may be associated with increased migration and miR-32 and miR-222 with decreased migration other hsa-mir-32 Glioma 28091986 miR-1227 may be associated with increased migration and miR-32 and miR-222 with decreased migration other hsa-mir-29b Wound Healing 28092445 miR-29b promotes skin wound healing and reduces excessive scar formation by inhibition of the TGF-¦Â1/Smad/CTGF signaling pathway. other hsa-mir-21 Breast Adenocarcinoma 28092843 "Moreover siRNA transfection had effects on breast adenocarcinoma cells and inhibits the migration (p<0.0001), proliferation (p<0.0001), cell cycle arrest (p=0.03) and induces apoptosis (p<0.0001) and reduces the expression of miR-21 (P=0.0014)" other hsa-mir-4775 Colorectal Carcinoma 28095858 miR-4775 promotes colorectal cancer invasion and metastasis via the Smad7/TGF¦Â-mediated epithelial to mesenchymal transition. other hsa-mir-221 "Carcinoma, Hepatocellular" 28096271 In Hepatocellular Carcinoma miR-221 Modulates Sorafenib Resistance through Inhibition of Caspase-3-Mediated Apoptosis. other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 28096685 The role of microRNA-21 in predicting brain metastases from non-small cell lung cancer. other hsa-mir-34a Myelofibrosis 28098757 "the increased expression of miR-34a-5p in PMF HPCs could be important for the skewing of megakaryopoiesis and the production of monocytes, that are key players in BM fibrosis in PMF patients" other hsa-mir-133b Colorectal Carcinoma 28098895 MicroRNA-133b is regulated by TAp63 while no gene mutation is present in colorectal cancer. other hsa-mir-152 Colorectal Carcinoma 28098901 "after treatment with berberine and evodiamine for 24?h, respectively, increased expression of DNMT1, DNMT3A, DNMT3B and miR-152, miR-429, miR-29a was noted" other hsa-mir-29a Colorectal Carcinoma 28098901 "after treatment with berberine and evodiamine for 24?h, respectively, increased expression of DNMT1, DNMT3A, DNMT3B and miR-152, miR-429, miR-29a was noted" other hsa-mir-429 Colorectal Carcinoma 28098901 "after treatment with berberine and evodiamine for 24?h, respectively, increased expression of DNMT1, DNMT3A, DNMT3B and miR-152, miR-429, miR-29a was noted" other hsa-mir-15a "Carcinoma, Renal Cell" 28098906 miR?15a?5p acts as an oncogene in renal cell carcinoma. other hsa-mir-203 "Carcinoma, Hepatocellular" 28100026 miR-203 inhibits augmented proliferation and metastasis of hepatocellular carcinoma residual in the promoted regenerating liver. other hsa-mir-142 Multiple Sclerosis 28100738 miR-142-3p Is a Key Regulator of IL-1¦Â-Dependent Synaptopathy in Neuroinflammation. other hsa-mir-25 "Adenocarcinoma, Lung" 28101226 Evaluation of plasma microRNA levels to predict insensitivity of patients with advanced lung adenocarcinomas to pemetrexed and platinum. other hsa-mir-146a "Carcinoma, Prostate" 28101571 Upregulation of miR-146a by YY1 depletion correlates with delayed progression of prostate cancer. other hsa-mir-650 "Carcinoma, Breast" 28101578 A 22q11.2 amplification in the region encoding microRNA-650 correlates with the epithelial to mesenchymal transition in breast cancer primary cultures of Mexican patients. other hsa-mir-126 Stroke 28101763 MiR-126 Affects Brain-Heart Interaction after Cerebral Ischemic Stroke. other hsa-mir-125b Cervical Neoplasms 28102867 "Gene regulation of the DEGs also revealed important TFs and miRNAs such as ELF1, SRF, has-mir-125b-5p and has-mir-644a" other hsa-mir-644a Cervical Neoplasms 28102867 "Gene regulation of the DEGs also revealed important TFs and miRNAs such as ELF1, SRF, has-mir-125b-5p and has-mir-644a" other hsa-mir-146a "Carcinoma, Thyroid" 28103112 "Potassium Iodate Differently Regulates the Proliferation, Migration, and Invasion of Human Thyroid Cancer Cells via Modulating miR-146a." other hsa-mir-133a Inflammatory Bowel Diseases 28104982 "miRNA-133a-UCP2 pathway regulates inflammatory bowel disease progress by influencing inflammation, oxidative stress and energy metabolism." other hsa-mir-145 "Carcinoma, Bladder" 28106737 A Novel Combination RNAi toward Warburg Effect by Replacement with miR-145 and Silencing of PTBP1 Induces Apoptotic Cell Death in Bladder Cancer Cells. other hsa-mir-130b Glioma 28107197 MTDH promotes glioma invasion through regulating miR-130b-ceRNAs. other hsa-mir-142 Adrenal Cortex Neoplasms 28110695 "MEN1 and microRNAs: The link between sporadic pituitary, parathyroid and adrenocortical tumors" other hsa-mir-24 Adrenal Cortex Neoplasms 28110695 "MEN1 and microRNAs: The link between sporadic pituitary, parathyroid and adrenocortical tumors" other hsa-mir-382 Hemangioma 28112362 Downregulation of miR-382 by propranolol inhibits the progression of infantile hemangioma via the PTEN-mediated AKT/mTOR pathway. other hsa-mir-145 "Carcinoma, Cervical" 28112371 MicroRNA-145 inhibits tumorigenesis and invasion of cervical cancer stem cells. other hsa-mir-126 Intracerebral Hemorrhage 28112373 Protective role of microRNA-126 in intracerebral hemorrhage. other hsa-mir-342 Glioma 28112756 Long noncoding RNA FTX is upregulated in gliomas and promotes proliferation and invasion of glioma cells by negatively regulating miR-342-3p. other hsa-mir-200c "Carcinoma, Gastric" 28113080 "MicroRNA-200c binding to FN1 suppresses the proliferation, migration and invasion of gastric cancer cells." other hsa-mir-1 Vascular Hypertrophy 28114137 Hydrogen Sulfide Protects Cardiomyocytes against Apoptosis in Ischemia/Reperfusion through MiR-1-Regulated Histone Deacetylase 4 Pathway. other hsa-mir-26b Adenovirus Infection 28114818 Functional Screening Identifies Human miRNAs that Modulate Adenovirus Propagation in Prostate Cancer Cells. other hsa-mir-122 "Carcinoma, Hepatocellular" 28114997 Targeted imaging and induction of apoptosis of drug-resistant hepatoma cells by miR-122-loaded graphene-InP nanocompounds. other hsa-mir-183 "Adenocarcinoma, Lung" 28115792 Identification of Factors for the Preoperative Prediction of Tumour Subtype and Prognosis in Patients with T1 Lung Adenocarcinoma. other hsa-mir-21 "Carcinoma, Breast" 28115844 Simultaneous delivery of anti-miR21 with doxorubicin prodrug by mimetic lipoprotein nanoparticles for synergistic effect against drug resistance in cancer cells. other hsa-mir-155 Rheumatoid Arthritis 28118944 MicroRNA-155 contributes to enhanced resistance to apoptosis in monocytes from patients with rheumatoid arthritis. other hsa-mir-508 Glioma 28121353 MiR-508-5p is a prognostic marker and inhibits cell proliferation and migration in glioma. other hsa-mir-29b "Carcinoma, Cervical" 28122338 Chemotherapy-mediated miR-29b expression inhibits the invasion and angiogenesis of cervical cancer. other hsa-mir-375 "Adenocarcinoma, Pancreatic Ductal" 28122349 The prognostic relevance of primary tumor location in patients undergoing resection for pancreatic ductal adenocarcinoma. other hsa-mir-27a "Carcinoma, Laryngeal" 28122350 Transcriptional suppression of microRNA-27a contributes to laryngeal cancer differentiation via GSK-3¦Â-involved Wnt/¦Â-catenin pathway. other hsa-mir-30e Atherosclerosis 28123167 "miR-30e in VSMCs exerted an anti-atherosclerosis effect via inhibiting proliferation and migration, and promoting apoptosis of VSMCs" other hsa-mir-143 Bladder Neoplasms 28123579 miR-143 inhibits bladder cancer cell proliferation and enhances their sensitivity to gemcitabine by repressing IGF-1R signaling. other hsa-mir-486 Lung Neoplasms 28124991 mir-660-p53-mir-486 Network: A New Key Regulatory Pathway in Lung Tumorigenesis. other hsa-mir-660 Lung Neoplasms 28124991 mir-660-p53-mir-486 Network: A New Key Regulatory Pathway in Lung Tumorigenesis. other hsa-mir-21 Pleural Mesothelioma 28125734 MiR-21-5p is suggested as novel regulator of MSLN with a possible functional role in cellular growth other hsa-mir-126 "Carcinoma, Breast" 28125889 Micro RNA-126 coordinates cell behavior and signaling cascades according to characteristics of breast cancer cells. other hsa-mir-133b Testicular Neoplasms 28126411 Perfluorooctanoic acid affects endocytosis involving clathrin light chain A and microRNA-133b-3p in mouse testes. other hsa-mir-125b "Leukemia, Lymphocytic, Chronic, B-Cell" 28126961 miR-125b and miR-532-3p predict the efficiency of rituximab-mediated lymphodepletion in chronic lymphocytic leukemia patients. A French Innovative Leukemia Organization study. other hsa-mir-532 "Leukemia, Lymphocytic, Chronic, B-Cell" 28126961 miR-125b and miR-532-3p predict the efficiency of rituximab-mediated lymphodepletion in chronic lymphocytic leukemia patients. A French Innovative Leukemia Organization study. other hsa-mir-222 Cardiovascular Diseases [unspecific] 28127557 MiR-222 in Cardiovascular Diseases: Physiology and Pathology. other hsa-mir-30c Diabetic Nephropathy 28127848 MiR-30c protects diabetic nephropathy by suppressing epithelial-to-mesenchymal transition in db/db mice. other hsa-mir-155 Myocardial Infarction 28129114 Macrophage-Derived mir-155-Containing Exosomes Suppress Fibroblast Proliferation and Promote Fibroblast Inflammation during Cardiac Injury. other hsa-mir-625 Melanoma 28129648 "microRNA-625 inhibits tumorigenicity by suppressing proliferation, migration and invasion in malignant melanoma." other hsa-mir-155 Myelodysplastic Syndromes 28130497 Mechanisms of Impaired Neutrophil Migration by MicroRNAs in Myelodysplastic Syndromes. other hsa-mir-34a Myelodysplastic Syndromes 28130497 Mechanisms of Impaired Neutrophil Migration by MicroRNAs in Myelodysplastic Syndromes. other hsa-mir-204 "Carcinoma, Gastric" 28133610 Histological and Pathological Assessment of miR-204 and SOX4 Levels in Gastric Cancer Patients. other hsa-mir-155 Neuroinflammation 28139244 MicroRNA 155 and viral-induced neuroinflammation. other hsa-mir-483 Osteoarthritis 28139355 Intra-articular Delivery of Antago-miR-483-5p Inhibits Osteoarthritis by Modulating Matrilin 3 and Tissue Inhibitor of Metalloproteinase 2. other hsa-mir-21 "Carcinoma, Bladder" 28139790 Formononetin inhibits human bladder cancer cell proliferation and invasiveness via regulation of miR-21 and PTEN. other hsa-mir-125a Melanoma 28140520 MicroRNA-125a promotes resistance to BRAF inhibitors through suppression of the intrinsic apoptotic pathway. other hsa-mir-126 Arteriosclerosis Obliterans 28143713 Intercellular transfer of miR-126-3p by endothelial microparticles reduces vascular smooth muscle cell proliferation and limits neointima formation by inhibiting LRP6. other hsa-mir-34a Neuroblastoma 28145567 nanoparticles encapsulating miR©\34a and conjugated to a GD2 antibody facilitated tumor©\specific delivery following systemic administration into tumor bearing mice other hsa-mir-135a Sepsis 28147298 MicroRNA-135a is up-regulated and aggravates myocardial depression in sepsis via regulating p38 MAPK/NF-¦ÊB pathway. other hsa-mir-132 Alzheimer Disease 28148775 microRNA-132: a key noncoding RNA operating in the cellular phase of Alzheimer's disease. other hsa-mir-126a Persistent Fetal Circulation Syndrome 28148930 MiR-126a-5p is involved in the hypoxia-induced endothelial-to-mesenchymal transition of neonatal pulmonary hypertension. other hsa-mir-200b "Carcinoma, Breast" 28152297 miR-200b and miR-217 negatively regulated the expression of autophagy marker proteins other hsa-mir-217 "Carcinoma, Breast" 28152297 miR-200b and miR-217 negatively regulated the expression of autophagy marker proteins other hsa-mir-10b Glioblastoma 28153089 Genome Editing Reveals Glioblastoma Addiction to MicroRNA-10b. other hsa-mir-24 "Carcinoma, Prostate" 28157714 The role of miR-24 as a race related genetic factor in prostate cancer. other hsa-mir-30a "Carcinoma, Lung, Non-Small-Cell" 28158983 CD73/NT5E is a target of miR-30a-5p and plays an important role in the pathogenesis of non-small cell lung cancer. other hsa-let-7b Cardiovascular Diseases [unspecific] 28159509 Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis. other hsa-mir-598 "Carcinoma, Colon" 28161537 miR-598 inhibits metastasis in colorectal cancer by suppressing JAG1/Notch2 pathway stimulating EMT. other hsa-mir-155 Neoplasms [unspecific] 28162271 Nitric Oxide: Genomic Instability And Synthetic Lethality. other hsa-mir-200 "Carcinoma, Colon" 28163188 Transcriptional repression of miR-200 family members by Nanog in colon cancer cells induces epithelial-mesenchymal transition (EMT). other hsa-mir-200b "Carcinoma, Colon" 28163188 Transcriptional repression of miR-200 family members by Nanog in colon cancer cells induces epithelial-mesenchymal transition (EMT). other hsa-mir-200c "Carcinoma, Colon" 28163188 Transcriptional repression of miR-200 family members by Nanog in colon cancer cells induces epithelial-mesenchymal transition (EMT). other hsa-mir-29b Lung Neoplasms 28164574 Expression and Function Analysis of MicroRNA-29b in Xuanwei Lung Cancer. other hsa-mir-143 Aortic Aneurysm 28167124 P38 MAPK Signaling Pathway Mediates Angiotensin II-Induced miR143/145 Gene Cluster Downregulation during Aortic Dissection Formation. other hsa-mir-145 Aortic Aneurysm 28167124 P38 MAPK Signaling Pathway Mediates Angiotensin II-Induced miR143/145 Gene Cluster Downregulation during Aortic Dissection Formation. other hsa-mir-29a Fatty Liver [unspecific] 28167804 miR-29a modulates SCD expression and is regulated in response to a saturated fatty acid diet in juvenile genetically improved farmed tilapia (Oreochromis niloticus). other hsa-mir-21 Myocardial Infarction 28170197 Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21. other hsa-mir-146b Diabetic Retinopathy 28170537 Adenosine Deaminase-2-Induced Hyperpermeability in Human Retinal Vascular Endothelial Cells Is Suppressed by MicroRNA-146b-3p. other hsa-mir-1285 Wound Healing 28175294 miRNAs that associate with conjunctival inflammation and ocular Chlamydia trachomatis infection do not predict progressive disease. other hsa-mir-147b Wound Healing 28175294 miRNAs that associate with conjunctival inflammation and ocular Chlamydia trachomatis infection do not predict progressive disease. other hsa-mir-155 Wound Healing 28175294 miRNAs that associate with conjunctival inflammation and ocular Chlamydia trachomatis infection do not predict progressive disease. other hsa-mir-184 Wound Healing 28175294 miRNAs that associate with conjunctival inflammation and ocular Chlamydia trachomatis infection do not predict progressive disease. other hsa-mir-214 "Carcinoma, Ovarian" 28175963 Curcumin suppresses cisplatin resistance development partly via modulating extracellular vesicle-mediated transfer of MEG3 and miR-214 in ovarian cancer. other hsa-mir-21 Colon Neoplasms 28176652 Mechanisms for the Inhibition of Colon Cancer Cells by Sulforaphane through Epigenetic Modulation of MicroRNA-21 and Human Telomerase Reverse Transcriptase (hTERT) Down-regulation. other hsa-mir-944 "Carcinoma, Endometrial" 28178620 miR-944 acts as a prognostic marker and promotes the tumor progression in endometrial cancer. other hsa-mir-17 "Carcinoma, Breast" 28178652 STAT3 is required for MiR-17-5p-mediated sensitization to chemotherapy-induced apoptosis in breast cancer cells. other hsa-mir-191 Glioblastoma 28178667 "Anti-GD2-ch14.18/CHO coated nanoparticles mediate glioblastoma (GBM)-specific delivery of the aromatase inhibitor, Letrozole, reducing proliferation, migration and chemoresistance in patient-derived GBM tumor cells." other hsa-mir-122 "Carcinoma, Hepatocellular" 28179291 Synergistic Inhibitory Effect of Traditional Chinese Medicine Astragaloside IV and Curcumin on Tumor Growth and Angiogenesis in an Orthotopic Nude-Mouse Model of Human Hepatocellular Carcinoma. other hsa-mir-100 Infection [unspecific] 28181552 MicroRNA-100 is involved in shrimp immune response to white spot syndrome virus (WSSV) and Vibrio alginolyticus infection. other hsa-mir-216 Acute Pancreatitis 28183420 Circulating microRNA 216 as a Marker for the Early Identification of Severe Acute Pancreatitis. other hsa-mir-183 Glioma 28184912 "Interaction between transcription factors PAX6/PAX6-5a and specific members of miR-183-96-182 cluster, may contribute to glioma progression in glioblastoma cell lines." other hsa-mir-365 "Carcinoma, Hepatocellular" 28184920 miR-365 targets ADAM10 and suppresses the cell growth and metastasis of hepatocellular carcinoma. other hsa-mir-181a "Leukemia, Lymphoblastic, Acute" 28184923 "miR-181a-5p, an inducer of Wnt-signaling, facilitates cell proliferation in acute lymphoblastic leukemia." other hsa-mir-34a "Diabetes Mellitus, Type 1" 28185128 Effects of TRPM7/miR-34a Gene Silencing on Spatial Cognitive Function and Hippocampal Neurogenesis in Mice with Type 1 Diabetes Mellitus. other hsa-mir-29b Neoplasms [unspecific] 28185889 MicroRNA hsa-miR-29b potentiates etoposide toxicity in HeLa cells via down-regulation of Mcl-1. other hsa-mir-196b Pancreatic Neoplasms 28186267 MicroRNA-196b is an independent prognostic biomarker in patients with pancreatic cancer. other hsa-mir-375 Colorectal Carcinoma 28186962 microRNA-375 inhibits colorectal cancer cells proliferation by downregulating JAK2/STAT3 and MAP3K8/ERK signaling pathways. other hsa-mir-29a "Carcinoma, Breast" 28186968 XIAP 3'-untranslated region as a ceRNA promotes FSCN1 function in inducing the progression of breast cancer by binding endogenous miR-29a-5p. other hsa-let-7a Vascular Hypertrophy 28187784 Let-7a-transfected mesenchymal stem cells ameliorate monocrotaline-induced pulmonary hypertension by suppressing pulmonary artery smooth muscle cell growth through STAT3-BMPR2 signaling. other hsa-mir-210 Inflammation 28188219 Distinct Effects of miR-210 Reduction on Neurogenesis: Increased Neuronal Survival of Inflammation But Reduced Proliferation Associated with Mitochondrial Enhancement. other hsa-mir-498 "Squamous Cell Carcinoma, Esophageal" 28188753 MiR-498 in esophageal squamous cell carcinoma: clinicopathological impacts and functional interactions. other hsa-mir-29b Crohn Disease 28190086 MCL-1 is modulated in Crohn's disease fibrosis by miR-29b via IL-6 and IL-8. other hsa-mir-221 "Carcinoma, Breast" 28191469 RNA-Binding Protein Dnd1 Promotes Breast Cancer Apoptosis by Stabilizing the Bim mRNA in a miR-221 Binding Site. other hsa-mir-30a Glioma 28192116 PRRT2 inhibits the proliferation of glioma cells by modulating unfolded protein response pathway. other hsa-mir-21 Colorectal Carcinoma 28192117 NR2F2 inhibits Smad7 expression and promotes TGF-¦Â-dependent epithelial-mesenchymal transition of CRC via transactivation of miR-21. other hsa-mir-346 Graves Disease 28192819 MiR-346 and TRAb as Predicative Factors for Relapse in Graves' Disease Within One Year. other hsa-mir-301a "Carcinoma, Colon" 28193514 MicroRNA 301A Promotes Intestinal Inflammation and Colitis-Associated Cancer Development by Inhibiting BTG1. other hsa-mir-22 Preeclampsia 28193709 Testosterone Represses Estrogen Signaling by Upregulating miR-22: A Mechanism for Imbalanced Steroid Hormone Production in Preeclampsia. other hsa-mir-34b Melanoma 28194372 MiR-34b-5p Suppresses Melanoma Differentiation-Associated Gene 5 (MDA5) Signaling Pathway to Promote Avian Leukosis Virus Subgroup J (ALV-J)-Infected Cells Proliferaction and ALV-J Replication. other hsa-mir-125a Neoplasms [unspecific] 28197019 Inflammation and Cancer: Extra- and Intracellular Determinants of Tumor-Associated Macrophages as Tumor Promoters. other hsa-mir-146a Neoplasms [unspecific] 28197019 Inflammation and Cancer: Extra- and Intracellular Determinants of Tumor-Associated Macrophages as Tumor Promoters. other hsa-mir-155 Neoplasms [unspecific] 28197019 Inflammation and Cancer: Extra- and Intracellular Determinants of Tumor-Associated Macrophages as Tumor Promoters. other hsa-mir-223 Neoplasms [unspecific] 28197019 Inflammation and Cancer: Extra- and Intracellular Determinants of Tumor-Associated Macrophages as Tumor Promoters. other hsa-mir-511 Neoplasms [unspecific] 28197019 Inflammation and Cancer: Extra- and Intracellular Determinants of Tumor-Associated Macrophages as Tumor Promoters. other hsa-mir-31 Lung Neoplasms 28197369 The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome. other hsa-mir-21 Cholangiocarcinoma 28197636 miR-21 and KLF4 jointly augment epithelial?mesenchymal transition via the Akt/ERK1/2 pathway. other hsa-mir-155 "Adenocarcinoma, Pancreatic Ductal" 28198398 MicroRNA-155 Controls Exosome Synthesis and Promotes Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma. other hsa-mir-185 Stroke 28199366 MicroRNAs regulating cluster of differentiation 46 (CD46) in cardioembolic and non-cardioembolic stroke. other hsa-mir-19a Stroke 28199366 MicroRNAs regulating cluster of differentiation 46 (CD46) in cardioembolic and non-cardioembolic stroke. other hsa-mir-20a Stroke 28199366 MicroRNAs regulating cluster of differentiation 46 (CD46) in cardioembolic and non-cardioembolic stroke. other hsa-mir-374b Stroke 28199366 MicroRNAs regulating cluster of differentiation 46 (CD46) in cardioembolic and non-cardioembolic stroke. other hsa-mir-221 "Carcinoma, Breast" 28202520 Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles. other hsa-mir-21 Glioma 28208619 "AKT Axis, miR-21, and RECK Play Pivotal Roles in Dihydroartemisinin Killing Malignant Glioma Cells." other hsa-mir-17 Celiac Disease 28208686 Identification of Autophagy-Related Genes and Their Regulatory miRNAs Associated with Celiac Disease in Children. other hsa-mir-30a Celiac Disease 28208686 Identification of Autophagy-Related Genes and Their Regulatory miRNAs Associated with Celiac Disease in Children. other hsa-mir-132 Inflammation 28209997 Antisense miR-132 blockade via the AChE-R splice variant mitigates cortical inflammation. other hsa-mir-375 "Squamous Cell Carcinoma, Lung" 28214218 Implication of downregulation and prospective pathway signaling of microRNA-375 in lung squamous cell carcinoma. other hsa-mir-29b Cerebral Aneurysm 28214880 MiR-29b Downregulation Induces Phenotypic Modulation of Vascular Smooth Muscle Cells: Implication for Intracranial Aneurysm Formation and Progression to Rupture. other hsa-mir-7 "Carcinoma, Ovarian" 28216373 TWEAK-stimulated macrophages inhibit metastasis of epithelial ovarian cancer via exosomal shuttling of microRNA. other hsa-mir-21 Leukemia 28218044 Leukemia microvesicles affect healthy hematopoietic stem cells. other hsa-mir-29a Leukemia 28218044 Leukemia microvesicles affect healthy hematopoietic stem cells. other hsa-mir-18a "Carcinoma, Hepatocellular" 28219903 MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer. other hsa-mir-223 "Carcinoma, Bladder" 28222670 MicroRNA-223-3p inhibits human bladder cancer cell migration and invasion. other hsa-mir-137 Neuroblastoma 28223126 Targeted inhibition of HDAC8 increases the doxorubicin sensitivity of neuroblastoma cells via up regulation of miR-137. other hsa-mir-125b "Carcinoma, Endometrial" 28225751 Proliferation and migration capability of endometrial carcinoma cells were detected after transfection of endometrial carcinoma cells with mir-125b mimic other hsa-mir-100 "Carcinoma, Bladder" 28229968 Cytotoxic and toxicogenomic effects of silibinin in bladder cancer cells with different TP53 status. other hsa-mir-203 "Carcinoma, Bladder" 28229968 Cytotoxic and toxicogenomic effects of silibinin in bladder cancer cells with different TP53 status. other hsa-mir-7 "Carcinoma, Lung, Non-Small-Cell" 28229971 Breviscapine suppresses the growth of non-small cell lung cancer by enhancing microRNA-7 expression. other hsa-mir-98 "Carcinoma, Breast" 28232182 SNHG16 contributes to breast cancer cell migration by competitively binding miR-98 with E2F5. other hsa-mir-181a Machado-Joseph Disease 28236575 Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease. other hsa-mir-494 Machado-Joseph Disease 28236575 Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease. other hsa-mir-9 Machado-Joseph Disease 28236575 Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease. other hsa-mir-21 Colorectal Carcinoma 28236743 Direct binding of microRNA-21 pre-element with Regorafenib: An alternative mechanism for anti-colorectal cancer chemotherapy other hsa-mir-185 "Carcinoma, Hepatocellular" 28240051 MicroRNA-185 induces potent autophagy via AKT signaling in hepatocellular carcinoma. other hsa-mir-210 Neoplasms [unspecific] 28240549 Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit. other hsa-mir-30d "Carcinoma, Prostate" 28241827 MicroRNA-30d promotes angiogenesis and tumor growth via MYPT1/c-JUN/VEGFA pathway and predicts aggressive outcome in prostate cancer. other hsa-mir-142 "Carcinoma, Hepatocellular" 28243631 Identifying microRNA panels specifically associated with hepatocellular carcinoma and its different etiologies. other hsa-mir-135b Multiple Myeloma 28245421 "Compared with those of the normal ones, exosomes in MM have less miR-15a and/or more miR-135b and miR-21" other hsa-mir-15a Multiple Myeloma 28245421 "Compared with those of the normal ones, exosomes in MM have less miR-15a and/or more miR-135b and miR-21" other hsa-mir-21 Multiple Myeloma 28245421 "Compared with those of the normal ones, exosomes in MM have less miR-15a and/or more miR-135b and miR-21" other hsa-mir-200 "Carcinoma, Ovarian" 28245631 Role of Nerve Growth Factor (NGF) and miRNAs in Epithelial Ovarian Cancer. other hsa-mir-23b "Carcinoma, Ovarian" 28245631 Role of Nerve Growth Factor (NGF) and miRNAs in Epithelial Ovarian Cancer. other hsa-mir-17 Leukemia 28247308 Differential Maturation of miR-17?~?92 Cluster Members in Human Cancer Cell Lines. other hsa-mir-20a Leukemia 28247308 Differential Maturation of miR-17?~?92 Cluster Members in Human Cancer Cell Lines. other hsa-mir-92a Leukemia 28247308 Differential Maturation of miR-17?~?92 Cluster Members in Human Cancer Cell Lines. other hsa-mir-210 Heart Failure 28249798 "Mesenchymal stem cells-derived extracellular vesicles, via miR-210, improve infarcted cardiac function by promotion of angiogenesis." other hsa-mir-126 Human Immunodeficiency Virus Infection 28250134 MicroRNA miR-126-5p Enhances the Inflammatory Responses of Monocytes to Lipopolysaccharide Stimulation by Suppressing Cylindromatosis in Chronic HIV-1 Infection. other hsa-mir-660 "Carcinoma, Breast" 28252173 Inhibition of miR-660-5p expression suppresses tumor development and metastasis in human breast cancer. other hsa-mir-126 Cardiovascular Diseases [unspecific] 28253326 Prevention of neointimal formation using miRNA-126-containing nanoparticle-conjugated stents in a rabbit model. other hsa-mir-423 "Carcinoma, Gastric" 28254439 The microRNA-423-3p-Bim Axis Promotes Cancer Progression and Activates Oncogenic Autophagy in Gastric Cancer. other hsa-mir-150 Atherosclerosis 28254813 MicroRNA-150 Modulates Ischemia-Induced Neovascularization in Atherosclerotic Conditions. other hsa-mir-200c Lung Fibrosis 28255128 Recent advances in miR-200c and fibrosis in organs. other hsa-mir-195 Colorectal Carcinoma 28255246 miR-195 enhances the radiosensitivity of colorectal cancer cells by suppressing CARM1. other hsa-mir-155 Neoplasms [unspecific] 28256712 Oncogenic role of microRNA-155 in mycosis fungoides: an in vitro and xenograft mouse model study. other hsa-mir-138 "Carcinoma, Hepatocellular" 28258280 HCV core inhibits hepatocellular carcinoma cell replicative senescence through downregulating microRNA-138 expression. other hsa-mir-155 "Carcinoma, Colon" 28259135 "miR-155 is positively regulated by CBX7 in mouse embryonic fibroblasts and colon carcinomas, and targets the KRAS oncogene." other hsa-mir-30b "Carcinoma, Renal Cell" 28259953 Identification of miR?30b as an oncogene in renal cell carcinoma. other hsa-mir-34a Parkinson Disease 28259991 The involvement of Eag1 potassium channels and miR-34a in rotenone-induced death of dopaminergic SH-SY5Y cells. other hsa-mir-197 "Lymphoma, Burkitt" 28259992 EBV?BART?6?3p and cellular microRNA?197 compromise the immune defense of host cells in EBV?positive Burkitt lymphoma. other hsa-mir-145 "Osteoporosis, Postmenopausal" 28260003 Estrogen stimulates osteoprotegerin expression via the suppression of miR-145 expression in MG-63 cells. other hsa-mir-195 "Carcinoma, Renal Cell" 28260025 Identification of miR?195?3p as an oncogene in RCC. other hsa-mir-149 Crohn Disease 28260036 Comprehensive bioinformatics analyses of Crohn's disease. other hsa-mir-4447 Crohn Disease 28260036 Comprehensive bioinformatics analyses of Crohn's disease. other hsa-mir-106a Parkinson Disease 28260060 Bioinformatics analysis on the differentiation of bone mesenchymal stem cells into osteoblasts and adipocytes. other hsa-mir-203 Parkinson Disease 28260060 Bioinformatics analysis on the differentiation of bone mesenchymal stem cells into osteoblasts and adipocytes. other hsa-mir-376a Parkinson Disease 28260060 Bioinformatics analysis on the differentiation of bone mesenchymal stem cells into osteoblasts and adipocytes. other hsa-mir-382 Parkinson Disease 28260060 Bioinformatics analysis on the differentiation of bone mesenchymal stem cells into osteoblasts and adipocytes. other hsa-mir-495 Parkinson Disease 28260060 Bioinformatics analysis on the differentiation of bone mesenchymal stem cells into osteoblasts and adipocytes. other hsa-mir-543 Parkinson Disease 28260060 Bioinformatics analysis on the differentiation of bone mesenchymal stem cells into osteoblasts and adipocytes. other hsa-mir-373 Breast Neoplasms 28260305 Effects of microRNA-373 on the proliferation and invasiveness of breast carcinoma and its mechanisms. other hsa-mir-149 Chronic Obstructive Pulmonary Disease 28260877 Repression of Toll-like receptor-4 by microRNA-149-3p is associated with smoking-related COPD. other hsa-mir-143 "Diabetes Mellitus, Type 2" 28270439 Comprehensive functional screening of miRNAs involved in fat cell insulin sensitivity among women. other hsa-mir-652 "Diabetes Mellitus, Type 2" 28270439 Comprehensive functional screening of miRNAs involved in fat cell insulin sensitivity among women. other hsa-mir-21 Diabetic Retinopathy 28270521 Pathogenic Role of microRNA-21 in Diabetic Retinopathy Through Downregulation of PPAR¦Á. other hsa-mir-145 "Carcinoma, Colon" 28272349 The Influence of Spirulina platensis Filtrates on Caco-2 Proliferative Activity and Expression of Apoptosis-Related microRNAs and mRNA. other hsa-mir-146 "Carcinoma, Colon" 28272349 The Influence of Spirulina platensis Filtrates on Caco-2 Proliferative Activity and Expression of Apoptosis-Related microRNAs and mRNA. other hsa-mir-17 "Carcinoma, Colon" 28272349 The Influence of Spirulina platensis Filtrates on Caco-2 Proliferative Activity and Expression of Apoptosis-Related microRNAs and mRNA. other hsa-mir-9 "Leukemia, Myeloid, Acute" 28272704 A minicircuitry comprised of microRNA-9 and SIRT1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia. other hsa-mir-34a Lung Fibrosis 28273432 p53 and miR-34a Feedback Promotes Lung Epithelial Injury and Pulmonary Fibrosis. other hsa-mir-34a Hepatoblastoma 28277300 Exosomal miR-34s panel as potential novel diagnostic and prognostic biomarker in patients with hepatoblastoma. other hsa-mir-34b Hepatoblastoma 28277300 Exosomal miR-34s panel as potential novel diagnostic and prognostic biomarker in patients with hepatoblastoma. other hsa-mir-34c Hepatoblastoma 28277300 Exosomal miR-34s panel as potential novel diagnostic and prognostic biomarker in patients with hepatoblastoma. other hsa-mir-27a Diabetic Nephropathy 28277542 MicroRNA-27a promotes podocyte injury via PPAR¦Ã-mediated ¦Â-catenin activation in diabetic nephropathy. other hsa-mir-17 "Carcinoma, Pancreatic" 28280038 The NOP14/mutp53 axis suppressed p21 expression at both the transcriptional and posttranscriptional levels via induction of miR-17-5p in PDAC cells other hsa-mir-194 Colorectal Carcinoma 28280361 MicroRNA-194 modulates epithelial-mesenchymal transition in human colorectal cancer metastasis. other hsa-mir-489 "Carcinoma, Bladder" 28281959 miR-489 Suppresses Proliferation and Invasion of Human Bladder Cancer Cells. other hsa-mir-183 "Squamous Cell Carcinoma, Tongue" 28281960 miR-183 Modulates Cell Apoptosis and Proliferation in Tongue Squamous Cell Carcinoma SCC25 Cell Line. other hsa-mir-223 "Carcinoma, Lung" 28281961 MicroRNA-223 Promotes Tumor Progression in Lung Cancer A549 Cells via Activation of the NF-¦ÊB Signaling Pathway. other hsa-mir-155 "Lymphoma, Large B-Cell, Diffuse" 28281962 MicroRNA-155 Downregulation Promotes Cell Cycle Arrest and Apoptosis in Diffuse Large B-Cell Lymphoma. other hsa-mir-1284 "Carcinoma, Ovarian" 28281963 MicroRNA-1284 Inhibits Cell Viability and Induces Apoptosis of Ovarian Cancer Cell Line OVCAR3. other hsa-mir-126 Influenza 28282445 Endothelial cell tropism is a determinant of H5N1 pathogenesis in mammalian species. other hsa-mir-375 Prostate Neoplasms 28282880 Astaxanthin Inhibits PC-3 Xenograft Prostate Tumor Growth in Nude Mice. other hsa-mir-487b Prostate Neoplasms 28282880 Astaxanthin Inhibits PC-3 Xenograft Prostate Tumor Growth in Nude Mice. other hsa-mir-21 "Carcinoma, Lung" 28283413 Solasodine inhibits invasion of human lung cancer cell through downregulation of miR-21 and MMPs expression. other hsa-mir-133a Heart Failure 28283551 A novel role for miR-133a in centrally mediated activation of the renin-angiotensin system in congestive heart failure. other hsa-mir-122 Heart Diseases [unspecific] 28287427 The Role and Molecular Mechanism of Non-Coding RNAs in Pathological Cardiac Remodeling. other hsa-mir-184 Heart Diseases [unspecific] 28287427 The Role and Molecular Mechanism of Non-Coding RNAs in Pathological Cardiac Remodeling. other hsa-mir-34a Heart Diseases [unspecific] 28287427 The Role and Molecular Mechanism of Non-Coding RNAs in Pathological Cardiac Remodeling. other hsa-mir-942 Preeclampsia 28287888 MiR-942 decreased before 20 weeks gestation in women with preeclampsia and was associated with the pathophysiology of preeclampsia in vitro. other hsa-mir-106b Pituitary Adenoma 28288092 Effect of miR-106b on Invasiveness of Pituitary Adenoma via PTEN-PI3K/AKT. other hsa-mir-200 "Colitis, Ulcerative" 28288169 The miR-200 family is increased in dysplastic lesions in ulcerative colitis patients. other hsa-mir-15a "Diabetes Mellitus, Type 2" 28289072 Down-regulation of miR-15a/b accelerates fibrotic remodelling in the Type?2 diabetic human and mouse heart. other hsa-mir-15b "Diabetes Mellitus, Type 2" 28289072 Down-regulation of miR-15a/b accelerates fibrotic remodelling in the Type?2 diabetic human and mouse heart. other hsa-mir-223 Liver Injury 28295449 Hepatic mitochondrial DNA/Toll-like receptor 9/MicroRNA-223 forms a negative feedback loop to limit neutrophil overactivation and acetaminophen hepatotoxicity in mice. other hsa-mir-122 Chronic Hepatitis C 28295463 "Immune phenotype and function of natural killer and T cells in chronic hepatitis C patients who received a single dose of anti-MicroRNA-122, RG-101." other hsa-mir-33 Atherosclerosis 28296196 SIRT6 reduces macrophage foam cell formation by inducing autophagy and cholesterol efflux under ox-LDL condition. other hsa-mir-7 Alzheimer Disease 28296235 the circular RNA circular RNA sponge for miR-7 (ciRS-7) has an important role in regulating BACE1 and APP protein levels other hsa-mir-221 "Carcinoma, Thyroid, Papillary" 28297755 Expression of microRNA-221 and IL-17 in papillary thyroid carcinoma and correlation with clinicopathologic features. other hsa-mir-146a "Adenocarcinoma, Lung" 28299977 Identification of lymph node metastasis-related microRNAs in lung adenocarcinoma and analysis of the underlying mechanisms using a bioinformatics approach. other hsa-mir-150 "Adenocarcinoma, Lung" 28299977 Identification of lymph node metastasis-related microRNAs in lung adenocarcinoma and analysis of the underlying mechanisms using a bioinformatics approach. other hsa-mir-342 "Adenocarcinoma, Lung" 28299977 Identification of lymph node metastasis-related microRNAs in lung adenocarcinoma and analysis of the underlying mechanisms using a bioinformatics approach. other hsa-mir-375 "Carcinoma, Breast" 28300567 9-cis Retinoic acid modulates myotrophin expression and its miR in physiological and pathophysiological cell models. other hsa-mir-18a "Carcinoma, Hepatocellular" 28302149 Identification and interaction analysis of key genes and microRNAs in hepatocellular carcinoma by bioinformatics analysis. other hsa-mir-221 "Carcinoma, Hepatocellular" 28302149 Identification and interaction analysis of key genes and microRNAs in hepatocellular carcinoma by bioinformatics analysis. other hsa-mir-21 Neoplasms [unspecific] 28302473 Quantitative relationship between chemical properties and bioactivities of anti-microRNA oligonucleotides targeted to tumor-associated microRNA-21. other hsa-mir-4306 Neurodegenerative Diseases [unspecific] 28302480 Comprehensive investigation of aberrant microRNAs expression in cells culture model of MnCl2-induced neurodegenerative disease. other hsa-mir-186 "Carcinoma, Colon" 28302487 TUG1 mediates methotrexate resistance in colorectal cancer via miR-186/CPEB2 axis. other hsa-mir-205 "Carcinoma, Cervical" 28304186 miR-205 mediates the inhibition of cervical cancer cell proliferation using olmesartan. other hsa-mir-21 Pancreatic Neoplasms 28304379 Development of bioluminescent chick chorioallantoic membrane (CAM) models for primary pancreatic cancer cells: a platform for drug testing. other hsa-mir-7 "Squamous Cell Carcinoma, Esophageal" 28314263 Significance and Function of MicroRNA-7 in Oesophageal Squamous Cell Carcinoma. other hsa-mir-21 "Squamous Cell Carcinoma, Oral" 28314265 Next-generation Sequencing for microRNA Profiling: MicroRNA-21-3p Promotes Oral Cancer Metastasis. other hsa-mir-155 Lung Neoplasms 28315615 MIR155 Regulation of Ubiquilin1 and Ubiquilin2: Implications in Cellular Protection and Tumorigenesis. other hsa-mir-135b Multiple Myeloma 28316065 Identification of key genes and construction of microRNA-mRNA regulatory networks in multiple myeloma by integrated multiple GEO datasets using bioinformatics analysis. other hsa-mir-148a Multiple Myeloma 28316065 Identification of key genes and construction of microRNA-mRNA regulatory networks in multiple myeloma by integrated multiple GEO datasets using bioinformatics analysis. other hsa-mir-181 Vascular Injuries 28316180 Effect and related mechanism of microRNA-181 attenuates oxidized low density lipoprotein induced vascular endothelial cell injury. other hsa-mir-1 "Carcinoma, Prostate" 28317618 "MiR-1, a Potential Predictive Biomarker for Recurrence in Prostate Cancer After Radical Prostatectomy." other hsa-mir-32 Cardiovascular Diseases [unspecific] 28319142 MicroRNA-32 promotes calcification in vascular smooth muscle cells: Implications as a novel marker for coronary artery calcification. other hsa-mir-146a Infection [unspecific] 28319200 Induction of immunomodulatory miR-146a and miR-155 in small intestinal epithelium of Vibrio cholerae infected patients at acute stage of cholera. other hsa-mir-155 Infection [unspecific] 28319200 Induction of immunomodulatory miR-146a and miR-155 in small intestinal epithelium of Vibrio cholerae infected patients at acute stage of cholera. other hsa-mir-1 "Carcinoma, Prostate" 28320379 miRNAs associated with prostate cancer risk and progression. other hsa-mir-145 "Carcinoma, Prostate" 28320379 miRNAs associated with prostate cancer risk and progression. other hsa-mir-205 "Carcinoma, Prostate" 28320379 miRNAs associated with prostate cancer risk and progression. other hsa-mir-21 "Carcinoma, Prostate" 28320379 miRNAs associated with prostate cancer risk and progression. other hsa-mir-221 "Carcinoma, Prostate" 28320379 miRNAs associated with prostate cancer risk and progression. other hsa-mir-375 "Carcinoma, Prostate" 28320379 miRNAs associated with prostate cancer risk and progression. other hsa-mir-19b Wilms Tumor 28322459 "Effects of MicroRNA-19b on the Proliferation, Apoptosis, and Migration of Wilms' Tumor Cells Via the PTEN/PI3K/AKT Signaling Pathway." other hsa-mir-133 "Cardiomyopathy, Hypertrophic" 28322824 MicroRNA-133 mediates cardiac diseases: Mechanisms and clinical implications. other hsa-mir-608 Neuroinflammation 28326544 Personalized genetics of the cholinergic blockade of neuroinflammation. other hsa-mir-29c Meningioma 28327132 Simultaneous analysis of miRNA-mRNA in human meningiomas by integrating transcriptome: A relationship between PTX3 and miR-29c. other hsa-mir-30c Mitochondrial Metabolism Disease 28330939 Chlamydia preserves the mitochondrial network necessary for replication via microRNA-dependent inhibition of fission. other hsa-mir-34a "Carcinoma, Breast" 28334277 "In bone metastasis miR-34a-5p absence inversely correlates with Met expression, while Met oncogene is unaffected by miR-34a-5p in non-metastatic and metastatic breast carcinomas." other hsa-mir-200c "Carcinoma, Breast" 28334634 E3 Ubiquitin Ligase Cbl-b Prevents Tumor Metastasis by Maintaining the Epithelial Phenotype in Multiple Drug-Resistant Gastric and Breast Cancer Cells. other hsa-mir-184 "Carcinoma, Breast" 28335433 Evaluation and Adaptation of a Laboratory-Based cDNA Library Preparation Protocol for Retrospective Sequencing of Archived MicroRNAs from up to 35-Year-Old Clinical FFPE Specimens. other hsa-mir-221 "Carcinoma, Breast" 28335433 Evaluation and Adaptation of a Laboratory-Based cDNA Library Preparation Protocol for Retrospective Sequencing of Archived MicroRNAs from up to 35-Year-Old Clinical FFPE Specimens. other hsa-mir-29a "Carcinoma, Breast" 28335433 Evaluation and Adaptation of a Laboratory-Based cDNA Library Preparation Protocol for Retrospective Sequencing of Archived MicroRNAs from up to 35-Year-Old Clinical FFPE Specimens. other hsa-mir-363 "Carcinoma, Breast" 28335433 Evaluation and Adaptation of a Laboratory-Based cDNA Library Preparation Protocol for Retrospective Sequencing of Archived MicroRNAs from up to 35-Year-Old Clinical FFPE Specimens. other hsa-mir-375 "Carcinoma, Breast" 28335433 Evaluation and Adaptation of a Laboratory-Based cDNA Library Preparation Protocol for Retrospective Sequencing of Archived MicroRNAs from up to 35-Year-Old Clinical FFPE Specimens. other hsa-mir-455 "Carcinoma, Breast" 28335433 Evaluation and Adaptation of a Laboratory-Based cDNA Library Preparation Protocol for Retrospective Sequencing of Archived MicroRNAs from up to 35-Year-Old Clinical FFPE Specimens. other hsa-mir-548p Atherosclerosis 28336556 Human MicroRNA-548p Decreases Hepatic Apolipoprotein B Secretion and Lipid Synthesis. other hsa-mir-15a Breast Neoplasms 28337296 Tumor suppressor p53 induces miR-15a processing to inhibit neuronal apoptosis inhibitory protein (NAIP) in the apoptotic response DNA damage in breast cancer cell. other hsa-mir-155 "Carcinoma, Breast" 28338193 Oncogenic miR-155 down-regulated upon activation of antitumor cytotoxic T lymphocytes by the fusion of dendritic cells with breast carcinoma cells. other hsa-mir-576 "Carcinoma, Bladder" 28338199 MiR-576-3p is a novel marker correlated with poor clinical outcome in bladder cancer. other hsa-mir-486 Osteosarcoma 28339053 miR-486 suppresses the development of osteosarcoma by regulating PKC-¦Ä pathway. other hsa-mir-152 "Carcinoma, Hepatocellular" 28339081 HBx represses RIZ1 expression by DNA methyltransferase?1 involvement in decreased miR-152 in hepatocellular carcinoma. other hsa-mir-126 Sjogren Syndrome 28339625 Cystatin S-a candidate biomarker for severity of submandibular gland involvement in Sj?gren's syndrome. other hsa-mir-335 Sjogren Syndrome 28339625 Cystatin S-a candidate biomarker for severity of submandibular gland involvement in Sj?gren's syndrome. other hsa-mir-122 Liver Injury 28341748 Drug-induced liver injury: recent advances in diagnosis and risk assessment. other hsa-mir-124 Sepsis 28342874 Activation of PPAR¦Ã inhibits pro-inflammatory cytokines production by upregulation of miR-124 in?vitro and in?vivo. other hsa-mir-503 Hepatitis C Virus Infection 28343379 Hepatitis C Virus Nonstructural 5A Protein (HCV-NS5A) Inhibits Hepatocyte Apoptosis through the NF-¦Êb/miR-503/bcl-2 Pathway. other hsa-mir-551a "Carcinoma, Ovarian" 28345465 Demethoxycurcumin inhibited human epithelia ovarian cancer cells' growth via up-regulating miR-551a. other hsa-mir-9 Breast Neoplasms 28345661 Stepwise analysis of MIR9 loci identifies miR-9-5p to be involved in Oestrogen regulated pathways in breast cancer patients. other hsa-mir-21 Neoplasms [unspecific] 28346427 MiR-21 is required for anti-tumor immune response in mice: an implication for its bi-directional roles. other hsa-mir-205 "Carcinoma, Breast" 28346474 The microRNA-205-5p is correlated to metastatic potential of 21T series: A breast cancer progression model. other hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 28347234 "Clinical value of miR-145-5p in NSCLC and potential molecular mechanism exploration: A retrospective study based on GEO, qRT-PCR, and TCGA data." other hsa-mir-30 "Carcinoma, Breast" 28347244 The miR-30 family: Versatile players in breast cancer. other hsa-mir-125b "Carcinoma, Bladder" 28347246 MicroRNA-125b predicts clinical outcome and suppressed tumor proliferation and migration in human gallbladder cancer. other hsa-mir-186 Glioma 28351322 PVT1 affects growth of glioma microvascular endothelial cells by negatively regulating miR-186. other hsa-mir-203 Liver Cirrhosis 28355233 Coding and non-coding gene regulatory networks underlie the immune response in liver cirrhosis. other hsa-mir-219 Liver Cirrhosis 28355233 Coding and non-coding gene regulatory networks underlie the immune response in liver cirrhosis. other hsa-mir-34a "Carcinoma, Hepatocellular" 28356025 Regulation of Apoptosis by SYB in HepG2 Liver Cancer Cells is Mediated by the P53/Caspase 9 Axis. other hsa-mir-195 Colorectal Carcinoma 28356122 Integrated analysis identifies microRNA-195 as a suppressor of Hippo-YAP pathway in colorectal cancer. other hsa-mir-149 "Squamous Cell Carcinoma, Tongue" 28356969 MicroRNA-149 targets specificity protein 1 to suppress human tongue squamous cell carcinoma cell proliferation and motility. other hsa-mir-126 Multiple Sclerosis 28358058 MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium. other hsa-mir-92a Leukemia 28358188 Effective Integration of Targeted Tumor Imaging and Therapy Using Functionalized InP QDs with VEGFR2 Monoclonal Antibody and miR-92a Inhibitor. other hsa-mir-608 Muscle Diseases [unspecific] 28358823 Genome-wide association screens for Achilles tendon and ACL tears and tendinopathy. other hsa-mir-10b "Carcinoma, Renal Cell, Clear-Cell" 28360191 miR-10b is a prognostic marker in clear cell renal cell carcinoma. other hsa-mir-155 Hypertension 28360962 Novel Immune Mechanisms in Hypertension and Cardiovascular Risk. other hsa-mir-21 Hypertension 28360962 Novel Immune Mechanisms in Hypertension and Cardiovascular Risk. other hsa-mir-1249 "Carcinoma, Hepatocellular" 28365245 Induced MiR-1249 expression by aberrant activation of Hedegehog signaling pathway in hepatocellular carcinoma. other hsa-mir-181a Neuroblastoma 28365714 MicroRNA-181a Regulates Apoptosis and Autophagy Process in Parkinson's Disease by Inhibiting p38 Mitogen-Activated Protein Kinase (MAPK)/c-Jun N-Terminal Kinases (JNK) Signaling Pathways. other hsa-mir-210 Atherosclerosis 28367268 Protection of Human Umbilical Vein Endothelial Cells against Oxidative Stress by MicroRNA-210. other hsa-mir-21 Vascular Hypertrophy 28368454 Role and Regulation of MicroRNAs in Aldosterone-Mediated Cardiac Injury and Dysfunction in Male Rats. other hsa-mir-200b Colitis 28370348 miR-200b-containing microvesicles attenuate experimental colitis associated intestinal fibrosis by inhibiting epithelial-mesenchymal transition. other hsa-mir-451 Infection [unspecific] 28378118 miR-451 limits CD4+ T cell proliferative responses to infection in mice. other hsa-mir-21 Asthma 28379062 Inhibition of MicroRNA-21 by an antagomir ameliorates allergic inflammation in a mouse model of asthma. other hsa-mir-100 "Carcinoma, Gastric" 28381156 Characterization of exosomal RNAs derived from human gastric cancer cells by deep sequencing. other hsa-mir-148a "Carcinoma, Gastric" 28381156 Characterization of exosomal RNAs derived from human gastric cancer cells by deep sequencing. other hsa-mir-21 "Carcinoma, Gastric" 28381156 Characterization of exosomal RNAs derived from human gastric cancer cells by deep sequencing. other hsa-mir-30a "Carcinoma, Gastric" 28381156 Characterization of exosomal RNAs derived from human gastric cancer cells by deep sequencing. other hsa-let-7 "Carcinoma, Endometrial" 28381177 Dicer1 dysfunction promotes stemness and aggression in endometrial carcinoma. other hsa-mir-125a Leukemia 28381182 Involvement of miR-125a in resistance to daunorubicin by inhibiting apoptosis in leukemia cell lines. other hsa-mir-132 Fatty Liver [unspecific] 28381526 miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression. other hsa-mir-16 Bronchopulmonary Dysplasia 28381639 Thus the intergenerational effects of gestational SS involve epigenetic regulation of HIF-1¦Á through specific miRs contributing to increased incidence of AA and BPD in the progenies other hsa-mir-203 Pancreatic Neoplasms 28382422 The Role of Exosomes in Pancreatic Cancer Microenvironment. other hsa-mir-21 Pancreatic Neoplasms 28382422 The Role of Exosomes in Pancreatic Cancer Microenvironment. other hsa-mir-133a "Cardiomyopathy, Hypertrophic" 28382463 MicroRNAs Association in the Cardiac Hypertrophy Secondary to Complex Congenital Heart Disease in Children. other hsa-mir-21 "Cardiomyopathy, Hypertrophic" 28382463 MicroRNAs Association in the Cardiac Hypertrophy Secondary to Complex Congenital Heart Disease in Children. other hsa-mir-23b "Cardiomyopathy, Hypertrophic" 28382463 MicroRNAs Association in the Cardiac Hypertrophy Secondary to Complex Congenital Heart Disease in Children. other hsa-mir-24 "Cardiomyopathy, Hypertrophic" 28382463 MicroRNAs Association in the Cardiac Hypertrophy Secondary to Complex Congenital Heart Disease in Children. other hsa-mir-101 "Carcinoma, Prostate" 28384067 miR-101 Enhances Cisplatin-Induced DNA Damage Through Decreasing Nicotinamide Adenine Dinucleotide Phosphate Levels by Directly Repressing Tp53-Induced Glycolysis and Apoptosis Regulator Expression in Prostate Cancer Cells. other hsa-let-7d Lung Fibrosis 28385811 Modified mesenchymal stem cells using miRNA transduction alter lung injury in a bleomycin model. other hsa-mir-154 Lung Fibrosis 28385811 Modified mesenchymal stem cells using miRNA transduction alter lung injury in a bleomycin model. other hsa-mir-122 Chronic Hepatitis C 28389707 The Race of 10 Synthetic RNAi-Based Drugs to the Pharmaceutical Market. other hsa-mir-29c "Carcinoma, Colon" 28392396 p53 target miR-29c-3p suppresses colon cancer cell invasion and migration through inhibition of PHLDB2. other hsa-mir-155 Influenza 28392443 Enhanced immunogenicity following miR-155 incorporation into the influenza A virus genome. other hsa-mir-29b Infection [unspecific] 28394930 Analysis of host microRNA function uncovers a role for miR-29b-2-5p in Shigella capture by filopodia. other hsa-mir-21 Graft-Versus-Host Disease 28396121 Antagonism of profibrotic microRNA-21 improves?outcome of murine chronic renal allograft dysfunction. other hsa-mir-27b Ovarian Neoplasms 28396577 MicroRNA-27b functions as a new inhibitor of ovarian cancer-mediated vasculogenic mimicry through suppression of VE-cadherin expression. other hsa-mir-200b Ovarian Neoplasms 28399108 Decreased levels of baseline and drug-induced tubulin polymerisation are hallmarks of resistance to taxanes in ovarian cancer cells and are associated with epithelial-to-mesenchymal transition. other hsa-mir-200c Ovarian Neoplasms 28399108 Decreased levels of baseline and drug-induced tubulin polymerisation are hallmarks of resistance to taxanes in ovarian cancer cells and are associated with epithelial-to-mesenchymal transition. other hsa-mir-155 "Carcinoma, Lung" 28400205 "Titanium dioxide aggregating nanoparticles induce autophagy and under-expression of microRNA 21 and 30a in A549 cell line: A comparative study with cobalt(II, III) oxide nanoparticles." other hsa-mir-30a "Carcinoma, Lung" 28400205 "Titanium dioxide aggregating nanoparticles induce autophagy and under-expression of microRNA 21 and 30a in A549 cell line: A comparative study with cobalt(II, III) oxide nanoparticles." other hsa-mir-10a "Lymphoma, Burkitt" 28400759 Human and Epstein-Barr Virus miRNA Profiling as Predictive Biomarkers for Endemic Burkitt Lymphoma. other hsa-mir-21 Colorectal Carcinoma 28401648 Current Status and Perspectives Regarding LNA-Anti-miR Oligonucleotides and microRNA miR-21 Inhibitors as a Potential Therapeutic Option in Treatment of Colorectal Cancer. other hsa-mir-210 "Carcinoma, Breast, Triple Negative" 28402752 The MicroRNA miR-210 Is Expressed by Cancer Cells but Also by the Tumor Microenvironment in Triple-Negative Breast Cancer. other hsa-mir-155 Psoriasis 28402921 MiR-155 promotes cell proliferation and inhibits apoptosis by PTEN signaling pathway in the psoriasis. other hsa-mir-29 "Diabetes Mellitus, Type 2" 28404597 Altered miR-29 Expression in Type 2 Diabetes Influences Glucose and Lipid Metabolism in Skeletal Muscle. other hsa-mir-155 Atherosclerosis 28407320 Role of TLR4 and miR-155 in peripheral blood mononuclear cell-mediated inflammatory reaction in coronary slow flow and coronary arteriosclerosis patients. other hsa-mir-21 "Carcinoma, Gastric" 28407783 Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells. other hsa-let-7e "Squamous Cell Carcinoma, Esophageal" 28408353 ZEB1 induced miR-99b/let-7e/miR-125a cluster promotes invasion and metastasis in esophageal squamous cell carcinoma. other hsa-mir-125a "Squamous Cell Carcinoma, Esophageal" 28408353 ZEB1 induced miR-99b/let-7e/miR-125a cluster promotes invasion and metastasis in esophageal squamous cell carcinoma. other hsa-mir-99b "Squamous Cell Carcinoma, Esophageal" 28408353 ZEB1 induced miR-99b/let-7e/miR-125a cluster promotes invasion and metastasis in esophageal squamous cell carcinoma. other hsa-mir-122 Multiple Sclerosis 28411393 Global exosome transcriptome profiling reveals biomarkers for multiple sclerosis. other hsa-mir-24 "Squamous Cell Carcinoma, Tongue" 28413152 Loss of PTEN Expression Is Associated With High MicroRNA 24 Level and Poor Prognosis in Patients With Tongue Squamous Cell Carcinoma. other hsa-mir-21 Cardiovascular Diseases [unspecific] 28418864 Bone marrow-derived mesenchymal stem cells overexpressing MiR-21 efficiently repair myocardial damage in rats. other hsa-mir-519b Osteoarthritis 28423042 Transforming growth factor ¦Â1 enhances heme oxygenase 1 expression in human synovial fibroblasts by inhibiting microRNA 519b synthesis. other hsa-mir-155 Graft-Versus-Host Disease 28423578 Endothelial microparticles delivering microRNA-155 into T lymphocytes are involved in the initiation of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation. other hsa-mir-940 Ovarian Neoplasms 28423620 Exosomal miR-940 maintains SRC-mediated oncogenic activity in cancer cells: a possible role for exosomal disposal of tumor suppressor miRNAs. other hsa-mir-143 Glaucoma 28424493 Regulation of intraocular pressure by microRNA cluster miR-143/145. other hsa-mir-145 Glaucoma 28424493 Regulation of intraocular pressure by microRNA cluster miR-143/145. other hsa-mir-21 Neoplasms [unspecific] 28427524 Kallistatin suppresses cancer development by multi-factorial actions. other hsa-mir-33 Atherosclerosis 28428217 microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis. other hsa-mir-106b Glioma 28431179 miRNA Regulation in Gliomas: Usual Suspects in Glial Tumorigenesis and Evolving Clinical Applications. other hsa-mir-21 Glioma 28431179 miRNA Regulation in Gliomas: Usual Suspects in Glial Tumorigenesis and Evolving Clinical Applications. other hsa-mir-219 Glioma 28431179 miRNA Regulation in Gliomas: Usual Suspects in Glial Tumorigenesis and Evolving Clinical Applications. other hsa-mir-26a Glioma 28431179 miRNA Regulation in Gliomas: Usual Suspects in Glial Tumorigenesis and Evolving Clinical Applications. other hsa-mir-338 Glioma 28431179 miRNA Regulation in Gliomas: Usual Suspects in Glial Tumorigenesis and Evolving Clinical Applications. other hsa-mir-203 Colon Neoplasms 28431272 Specific microRNA-mRNA Regulatory Network of Colon Cancer Invasion Mediated by Tissue Kallikrein-Related Peptidase 6. other hsa-mir-155 "Leukemia, Myeloid, Acute" 28432220 miR-155 promotes FLT3-ITD-induced myeloproliferative disease through inhibition of the interferon response. other hsa-mir-130b Diabetes Mellitus 28433632 inhibition of miR-130b-3p appears to improve mitochondrial biogenesis signaling and protect placental trophoblast cells from oxidative stress other hsa-mir-93 "Carcinoma, Esophageal" 28434073 Direct Downregulation of B-Cell Translocation Gene 3 by microRNA-93 Is Required for Desensitizing Esophageal Cancer to Radiotherapy. other hsa-mir-34a "Carcinoma, Rectal" 28435028 Antagonistic Effects of p53 and HIF1A on microRNA-34a Regulation of PPP1R11 and STAT3 and Hypoxia-induced Epithelial to Mesenchymal Transition in Colorectal Cancer Cells. other hsa-mir-98 Atherosclerosis 28436142 Cortisol is associated with low frequency of interleukin 10-producing B cells in patients with atherosclerosis. other hsa-mir-21 Sepsis 28437377 MicroRNA-21 Is Required for Local and Remote Ischemic Preconditioning in Multiple Organ Protection Against Sepsis. other hsa-mir-214 Liver Diseases [unspecific] 28438567 A systematic evaluation of microRNAs in regulating human hepatic CYP2E1. other hsa-mir-942 Liver Diseases [unspecific] 28438567 A systematic evaluation of microRNAs in regulating human hepatic CYP2E1. other hsa-mir-21 Pancreatic Neoplasms 28438662 Never let it go: Stopping key mechanisms underlying metastasis to fight pancreatic cancer. other hsa-mir-451 Glioblastoma 28440461 "The role of miR-451 in the switching between proliferation and migration in malignant glioma cells: AMPK signaling, mTOR modulation and Rac1 activation required." other hsa-mir-122 Chronic Hepatitis C 28442604 Hepatitis C Virus Indirectly Disrupts DNA Damage-Induced p53 Responses by Activating Protein Kinase R. other hsa-mir-140 Glioma 28443475 MicroRNA-140-5p inhibits cell proliferation and invasion by regulating VEGFA/MMP2 signaling in glioma. other hsa-let-7 Neoplasms [unspecific] 28446596 Dicer loss and recovery induce an oncogenic switch driven by transcriptional activation of the oncofetal Imp1-3 family. other hsa-mir-21 Cervical Neoplasms 28447761 miR-21 inhibitor suppresses cell proliferation and colony formation through regulating the PTEN/AKT pathway and improves paclitaxel sensitivity in cervical cancer cells. other hsa-mir-7 "Carcinoma, Pancreatic" 28450156 microRNA-7 impairs autophagy-derived pools of glucose to suppress pancreatic cancer progression. other hsa-mir-21 Brain Disease [unspecific] 28452880 Acute and subacute microRNA dysregulation is associated with cytokine responses in the rodent model of penetrating ballistic-like brain injury. other hsa-mir-122 Chronic Hepatitis C 28456022 Cellular DEAD-box RNA helicase DDX6 modulates interaction of miR-122 with the 5' untranslated region of hepatitis C virus RNA. other hsa-mir-372 "Carcinoma, Ovarian" 28456593 The role of miR-372 in ovarian carcinoma cell proliferation. other hsa-mir-210 "Squamous Cell Carcinoma, Oral" 28459203 "Leptin acts on neoplastic behavior and expression levels of genes related to hypoxia, angiogenesis, and invasiveness in oral squamous cell carcinoma." other hsa-mir-7 "Carcinoma, Hepatocellular" 28459371 Role of microRNA-7 and selenoprotein P in hepatocellular carcinoma. other hsa-mir-7 Glioblastoma 28459998 Identification of miRNA-7 by genome-wide analysis as a critical sensitizer for TRAIL-induced apoptosis in glioblastoma cells. other hsa-mir-30a Breast Neoplasms 28461244 miR-30a-5p suppresses breast tumor growth and metastasis through inhibition of LDHA-mediated Warburg effect. other hsa-mir-21 Cardiovascular Diseases [unspecific] 28465657 The MicroRNA-21 signaling pathway is involved in prorenin receptor (PRR) -induced VEGF expression in ARPE-19 cells under a hyperglycemic condition. other hsa-mir-21 Vascular Hypertrophy 28465975 "Review in Translational Cardiology: MicroRNAs and Myocardial Fibrosis in Aortic Valve Stenosis, a Deep Insight on Left Ventricular Remodeling." other hsa-mir-146a "Carcinoma, Colon" 28466779 MicroRNA-146a induces immune suppression and drug-resistant colorectal cancer cells. other hsa-mir-1 Preeclampsia 28466998 Cardiac remodelling and preeclampsia: an overview of overlapping miRNAs. other hsa-mir-195 Preeclampsia 28466998 Cardiac remodelling and preeclampsia: an overview of overlapping miRNAs. other hsa-mir-29b Preeclampsia 28466998 Cardiac remodelling and preeclampsia: an overview of overlapping miRNAs. other hsa-mir-21 Prostate Neoplasms 28467474 Tonic suppression of PCAT29 by the IL-6 signaling pathway in prostate cancer: Reversal by resveratrol. other hsa-mir-1180 "Carcinoma, Hepatocellular" 28468075 Bioinformatics on vascular invasion markers in hepatocellular carcinoma via Big-Data analysis. other hsa-mir-149 "Carcinoma, Hepatocellular" 28468075 Bioinformatics on vascular invasion markers in hepatocellular carcinoma via Big-Data analysis. other hsa-mir-744 "Carcinoma, Hepatocellular" 28468075 Bioinformatics on vascular invasion markers in hepatocellular carcinoma via Big-Data analysis. other hsa-mir-940 "Carcinoma, Hepatocellular" 28468075 Bioinformatics on vascular invasion markers in hepatocellular carcinoma via Big-Data analysis. other hsa-mir-155 Preeclampsia 28471953 "Association of microRNA-155, interleukin 17A, and proteinuria in preeclampsia." other hsa-mir-29b Bronchopulmonary Dysplasia 28473324 miR-29b supplementation decreases expression of matrix proteins and improves alveolarization in mice exposed to maternal inflammation and neonatal hyperoxia. other hsa-mir-204 Hypertension 28473439 Implication of Inflammation and Epigenetic Readers in Coronary Artery Remodeling in Patients With Pulmonary Arterial Hypertension. other hsa-mir-223 Hypertension 28473439 Implication of Inflammation and Epigenetic Readers in Coronary Artery Remodeling in Patients With Pulmonary Arterial Hypertension. other hsa-mir-122 Hepatitis C Virus Infection 28475652 Serum microRNA-122 and Wisteria floribunda agglutinin-positive Mac-2 binding protein are useful tools for liquid biopsy of the patients with hepatitis B virus and advanced liver fibrosis. other hsa-mir-26a "Squamous Cell Carcinoma, Esophageal" 28476684 miR-26a and miR-26b inhibit esophageal squamous cancer cell proliferation through suppression of c-MYC pathway. other hsa-mir-26b "Squamous Cell Carcinoma, Esophageal" 28476684 miR-26a and miR-26b inhibit esophageal squamous cancer cell proliferation through suppression of c-MYC pathway. other hsa-mir-9 "Carcinoma, Gastric" 28476807 Expression of hsa-miR-9 and MYC Copy Number Variation in Hereditary Diffuse Gastric Cancer. other hsa-mir-18a Retinoblastoma 28481041 Reduction of the tumorigenic potential of human retinoblastoma cell lines by TFF1 overexpression involves p53/caspase signaling and miR-18a regulation. other hsa-let-7 Melanoma 28482074 The overexpression of Lin28B reduced mature let-7 microRNA expression in melanoma cell lines other hsa-mir-181a "Carcinoma, Prostate" 28485104 MicroRNA-181a promotes docetaxel resistance in prostate cancer cells. other hsa-mir-1 Gastric Neoplasms 28493075 MicroRNA-1 acts as a tumor suppressor microRNA by inhibiting angiogenesis-related growth factors in human gastric cancer. other hsa-mir-122 Chronic Hepatitis C 28494029 Characterization of miR-122-independent propagation of HCV. other hsa-let-7a Glioblastoma 28494471 Inhibition of neurotensin receptor 1 induces intrinsic apoptosis via let-7a-3p/Bcl-w axis in glioblastoma. other hsa-mir-21 Peritoneal Dialysis Failure 28495592 miR-21 Promotes Fibrogenesis in Peritoneal Dialysis. other hsa-mir-15a Chronic Hepatitis B 28498453 The inhibition of microRNA-15a suppresses hepatitis?B virus-associated liver cancer cell growth through the Smad/TGF-¦Â pathway. other hsa-mir-125a "Carcinoma, Pancreatic" 28498896 "targeting the overexpression of PRDM14 suppresses cancer stem-like phenotypes, including liver metastasis, via miRNA regulation and siRNA-based therapy targeting it shows promise as a treatment for patients with pancreatic cancer" other hsa-mir-24 Neoplasms [unspecific] 28500171 Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth. other hsa-mir-200b Liver Cirrhosis 28502477 Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b. other hsa-mir-15a Breast Neoplasms 28509572 Effect of silibinin-loaded nano-niosomal coated with trimethyl chitosan on miRNAs expression in 2D and 3D models of T47D breast cancer cell line. other hsa-mir-21 Breast Neoplasms 28509572 Effect of silibinin-loaded nano-niosomal coated with trimethyl chitosan on miRNAs expression in 2D and 3D models of T47D breast cancer cell line. other hsa-mir-133a Coronary Artery Disease 28511772 Transcoronary Concentration Gradient of microRNA-133a and Outcome in Patients With Coronary Artery Disease. other hsa-mir-34a Neoplasms [unspecific] 28511876 Chondroitin sulfate-functionalized polyamidoamine as a tumor-targeted carrier for miR-34a delivery. other hsa-mir-34 "Adenocarcinoma, Lung" 28512015 The association between miR-34 dysregulation and distant metastases formation in lung adenocarcinoma. other hsa-mir-10b Breast Ductal Carcinoma 28512126 Tumor-associated myoepithelial cells promote the invasive progression of ductal carcinoma in situ through activation of TGF¦Â signaling. other hsa-mir-378 Melanoma 28513838 The emerging role of NPNT in tissue injury repair and bone homeostasis. other hsa-mir-146a Rheumatoid Arthritis 28514293 The role of circulating miR-146a in patients with rheumatoid arthritis treated by Tripterygium wilfordii Hook F. other hsa-mir-223 Sepsis 28515178 A model-specific role of microRNA-223 as a mediator of kidney injury during experimental sepsis. other hsa-mir-125b "Carcinoma, Hepatocellular" 28521446 Candidate miRNAs and pathogenesis investigation for hepatocellular carcinoma based on bioinformatics analysis. other hsa-mir-21 Polycythemia Vera 28522758 Decreased CAT results from hypoxia-induced miR-21 that downregulates CAT other hsa-mir-133a Vascular Hypertrophy 28526870 these c-miRNAs may serve as markers for monitoring the RT responses other hsa-mir-21 Vascular Hypertrophy 28526870 these c-miRNAs may serve as markers for monitoring the RT responses other hsa-mir-199a "Carcinoma, Hepatocellular" 28529584 Anti-microRNA-21/221 and microRNA-199a transfected by ultrasound microbubbles induces the apoptosis of human hepatoma HepG2 cells. other hsa-mir-21 "Carcinoma, Hepatocellular" 28529584 Anti-microRNA-21/221 and microRNA-199a transfected by ultrasound microbubbles induces the apoptosis of human hepatoma HepG2 cells. other hsa-mir-221 "Carcinoma, Hepatocellular" 28529584 Anti-microRNA-21/221 and microRNA-199a transfected by ultrasound microbubbles induces the apoptosis of human hepatoma HepG2 cells. other hsa-mir-375 "Adenocarcinoma, Lung" 28533502 miR-375 is essential for the progression of LUAD other hsa-mir-92a "Carcinoma, Lung, Non-Small-Cell" 28534966 MicroRNA-92a promotes epithelial-mesenchymal transition through activation of PTEN/PI3K/AKT signaling pathway in non-small cell lung cancer metastasis. other hsa-mir-129 Chondrosarcoma 28535514 MiR-129-5p Inhibits Proliferation and Invasion of Chondrosarcoma Cells by Regulating SOX4/Wnt/¦Â-Catenin Signaling Pathway. other hsa-mir-145 "Adenocarcinoma, Lung" 28535533 MALAT1 Modulates TGF-¦Â1-Induced Endothelial-to-Mesenchymal Transition through Downregulation of miR-145. other hsa-mir-33b Endometriosis 28537685 "MiR-33b can mediate cell apoptosis, alter VEGF and MMP-9 expression and affect proliferation and apoptosis of uterus endometrial cells, thus participating endometriosis formation" other hsa-mir-126 Hemangioma 28538565 Urinary Excretion of MicroRNA-126 Is a Biomarker for Hemangioma Proliferation. other hsa-mir-199a "Carcinoma, Colon" 28542779 Downregulation of miR-199a/b-5p is associated with GCNT2 induction upon epithelial-mesenchymal transition in colon cancer. other hsa-mir-199b "Carcinoma, Colon" 28542779 Downregulation of miR-199a/b-5p is associated with GCNT2 induction upon epithelial-mesenchymal transition in colon cancer. other hsa-mir-34a Bone Disease [unspecific] 28543623 Regulatory effect of microRNA-34a on osteogenesis and angiogenesis in glucocorticoid-induced osteonecrosis of the femoral head. other hsa-mir-146a Arthritis 28545737 MicroRNA-146a governs fibroblast activation and joint pathology in arthritis. other hsa-mir-146a Human Papilloma Virus Infection 28551628 Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice. other hsa-mir-150 Human Papilloma Virus Infection 28551628 Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice. other hsa-let-7a Spinal Cord Injuries 28552531 A causal relationship between the neurotherapeutic effects of miR182/7a and decreased expression of PRDM5. other hsa-mir-182 Spinal Cord Injuries 28552531 A causal relationship between the neurotherapeutic effects of miR182/7a and decreased expression of PRDM5. other hsa-mir-1 "Carcinoma, Colon" 28560697 The Cardiotoxic Mechanism of Doxorubicin (DOX) and Pegylated Liposomal DOX in Mice Bearing C-26 Colon Carcinoma: a Study Focused on microRNA Role for Toxicity Assessment of New Formulations. other hsa-mir-21 "Carcinoma, Colon" 28560697 The Cardiotoxic Mechanism of Doxorubicin (DOX) and Pegylated Liposomal DOX in Mice Bearing C-26 Colon Carcinoma: a Study Focused on microRNA Role for Toxicity Assessment of New Formulations. other hsa-mir-204 Hypertension 28565757 An exploratory study into the role of miR-204-5p in pregnancy-induced hypertension. other hsa-mir-214 "Carcinoma, Gingival" 28565877 Elucidating the mechanism of miRNA-214 in the regulation of gingival carcinoma. other hsa-mir-200c Colorectal Carcinoma 28567416 Negative Correlation between miR-200c and Decorin Plays an Important Role in the Pathogenesis of Colorectal Carcinoma. other hsa-mir-7 "Carcinoma, Breast" 28571043 MicroRNA-7 suppresses the homing and migration potential of human endothelial cells to highly metastatic human breast cancer cells. other hsa-mir-183 Neuropathic Pain 28572455 miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes. other hsa-mir-375 "Carcinoma, Hepatocellular" 28577837 MiR-375 delivered by lipid-coated doxorubicin-calcium carbonate nanoparticles overcomes chemoresistance in hepatocellular carcinoma. other hsa-mir-502 "Carcinoma, Prostate" 28578017 Functional polymorphism at the miR-502-binding site in the 3' untranslated region of the SETD8 gene increased the risk of prostate cancer in a sample of Iranian population. other hsa-mir-21 Infection [unspecific] 28589100 MicroRNA-21 Limits Uptake of Listeria monocytogenes by Macrophages to Reduce the Intracellular Niche and Control Infection. other hsa-mir-21 Human Cytomegalovirus Infection 28589873 Human cytomegalovirus microRNAs are carried by virions and dense bodies and are delivered to target cells. other hsa-mir-218 Human Cytomegalovirus Infection 28589873 Human cytomegalovirus microRNAs are carried by virions and dense bodies and are delivered to target cells. other hsa-mir-128 Glioblastoma 28591575 MicroRNA-Mediated Dynamic Bidirectional Shift between the Subclasses of Glioblastoma Stem-like Cells. other hsa-mir-34a Acute Pancreatitis 28592850 NAD+ augmentation ameliorates acute pancreatitis through regulation of inflammasome signalling. other hsa-mir-500 Human Immunodeficiency Virus Infection 28594894 "MicroRNAs upregulated during HIV infection target peroxisome biogenesis factors: Implications for virus biology, disease mechanisms and neuropathology." other hsa-mir-93 Human Immunodeficiency Virus Infection 28594894 "MicroRNAs upregulated during HIV infection target peroxisome biogenesis factors: Implications for virus biology, disease mechanisms and neuropathology." other hsa-mir-146a Psoriasis 28595995 miR-146b Probably Assists miRNA-146a in?the Suppression of Keratinocyte Proliferation and Inflammatory Responses?in Psoriasis. other hsa-mir-146b Psoriasis 28595995 miR-146b Probably Assists miRNA-146a in?the Suppression of Keratinocyte Proliferation and Inflammatory Responses?in Psoriasis. other hsa-mir-143 Preterm Labor 28596604 "miR-143 and miR-145 disrupt the cervical epithelial barrier through dysregulation of cell adhesion, apoptosis and proliferation." other hsa-mir-145 Preterm Labor 28596604 "miR-143 and miR-145 disrupt the cervical epithelial barrier through dysregulation of cell adhesion, apoptosis and proliferation." other hsa-mir-125b "Carcinoma, Renal Cell" 28599452 "miR-125b is associated with renal cell carcinoma cell migration, invasion and apoptosis." other hsa-mir-21 Neuroblastoma 28599474 Reduction of miR-21 induces SK-N-SH cell apoptosis and inhibits proliferation via PTEN/PDCD4. other hsa-mir-34a Ischemia-Reperfusion Injury 28599575 Suppression of miR-34a Expression in the Myocardium Protects Against Ischemia-Reperfusion Injury Through SIRT1 Protective Pathway. other hsa-mir-494 Spinal Cord Injuries 28601045 MicroRNA-494 improves functional recovery and inhibits apoptosis by modulating PTEN/AKT/mTOR pathway in rats after spinal cord injury. other hsa-mir-101 "Carcinoma, Ovarian" 28601063 "Clusters of microRNAs (miR-145, miR-31, miR-506, miR-101) most essential for metastasis of ovarian cancer including the families of microRNAs (miR-200, miR-214, miR-25) with dual role" other hsa-mir-145 "Carcinoma, Ovarian" 28601063 "Clusters of microRNAs (miR-145, miR-31, miR-506, miR-101) most essential for metastasis of ovarian cancer including the families of microRNAs (miR-200, miR-214, miR-25) with dual role" other hsa-mir-200 "Carcinoma, Ovarian" 28601063 "Clusters of microRNAs (miR-145, miR-31, miR-506, miR-101) most essential for metastasis of ovarian cancer including the families of microRNAs (miR-200, miR-214, miR-25) with dual role" other hsa-mir-214 "Carcinoma, Ovarian" 28601063 "Clusters of microRNAs (miR-145, miR-31, miR-506, miR-101) most essential for metastasis of ovarian cancer including the families of microRNAs (miR-200, miR-214, miR-25) with dual role" other hsa-mir-25 "Carcinoma, Ovarian" 28601063 "Clusters of microRNAs (miR-145, miR-31, miR-506, miR-101) most essential for metastasis of ovarian cancer including the families of microRNAs (miR-200, miR-214, miR-25) with dual role" other hsa-mir-31 "Carcinoma, Ovarian" 28601063 "Clusters of microRNAs (miR-145, miR-31, miR-506, miR-101) most essential for metastasis of ovarian cancer including the families of microRNAs (miR-200, miR-214, miR-25) with dual role" other hsa-mir-506 "Carcinoma, Ovarian" 28601063 "Clusters of microRNAs (miR-145, miR-31, miR-506, miR-101) most essential for metastasis of ovarian cancer including the families of microRNAs (miR-200, miR-214, miR-25) with dual role" other hsa-mir-24 Liver Fibrosis 28602220 Inhibition of microRNA-24 increases liver fibrosis by enhanced menin expression in Mdr2-/- mice. other hsa-mir-146a Amyotrophic Lateral Sclerosis 28612258 Downregulated Glia Interplay and Increased miRNA-155 as Promising Markers to Track ALS at an?Early Stage. other hsa-mir-155 Amyotrophic Lateral Sclerosis 28612258 Downregulated Glia Interplay and Increased miRNA-155 as Promising Markers to Track ALS at an?Early Stage. other hsa-mir-371a Testicular Germ Cell Tumor 28612337 microRNA-371a-3p as informative biomarker for the follow-up of testicular germ cell cancer patients. other hsa-mir-125b Melanoma 28614272 Quantification of microRNA-21 and microRNA-125b in melanoma tissue. other hsa-mir-205 Melanoma 28614272 Quantification of microRNA-21 and microRNA-125b in melanoma tissue. other hsa-mir-182 Autism Spectrum Disorder 28617945 microRNA cluster 106a~363 is involved in T helper 17 cell differentiation. other hsa-mir-212 Autism Spectrum Disorder 28617945 microRNA cluster 106a~363 is involved in T helper 17 cell differentiation. other hsa-mir-363 Autism Spectrum Disorder 28617945 microRNA cluster 106a~363 is involved in T helper 17 cell differentiation. other hsa-mir-124 Stroke 28624203 Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia. other hsa-mir-494 Ischemic Diseases [unspecific] 28624225 Inhibition of Mef2a Enhances Neovascularization via Post-transcriptional Regulation of 14q32 MicroRNAs miR-329 and miR-494. other hsa-mir-21 Breast Neoplasms 28628833 Urtica dioica extract suppresses miR-21 and metastasis-related genes in breast cancer. other hsa-mir-451 Glioblastoma 28629521 Erythropoietin Promotes Glioblastoma via miR-451 Suppression. other hsa-mir-200a Esophageal Neoplasms 28635228 MALAT1 functions as a competing endogenous RNA to regulate the expressions of ZEB1 and ZEB2 by sponging miR-200a and promotes invasion and migration of esophageal cancer cells through inducing epithelial-mesenchymal transition other hsa-mir-34a Osteosarcoma 28635396 MicroRNA-34a inhibits tumor invasion and metastasis in osteosarcoma partly by effecting C-IAP2 and Bcl-2. other hsa-mir-146a Muscular Dystrophy 28637335 Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy. other hsa-mir-146a Atherosclerosis 28637783 Paradoxical Suppression of Atherosclerosis in the Absence of microRNA-146a. other hsa-mir-155 Ischemia-Reperfusion Injury 28640790 MicroRNA-155 Deficiency in Kupffer Cells Ameliorates Liver Ischemia-Reperfusion Injury in Mice. other hsa-mir-145 Prostate Neoplasms 28641312 Impact of novel miR-145-3p regulatory networks on survival in patients with castration-resistant prostate cancer. other hsa-mir-155 Human Cytomegalovirus Infection 28642130 mir-155 expression is downregulated in kidney transplant patients with human cytomegalovirus infection. other hsa-mir-122 "Carcinoma, Hepatocellular" 28642869 Detection of MicroRNA in Hepatic Cirrhosis and Hepatocellular Carcinoma in Hepatitis C Genotype-4 in Egyptian Patients. other hsa-mir-122 Chronic Hepatitis C 28642978 Ectopic delivery of miR-200c diminishes hepatitis C virus infectivity through transcriptional and translational repression of Occludin. other hsa-mir-140 Gout 28647469 Intra-articular injection of microRNA-140 (miRNA-140) alleviates osteoarthritis (OA) progression by modulating extracellular matrix (ECM) homeostasis in rats. other hsa-mir-30d "Carcinoma, Colon" 28651493 Mir-30d suppresses cell proliferation of colon cancer cells by inhibiting cell autophagy and promoting cell apoptosis. other hsa-mir-34a Alzheimer Disease 28652929 TNF-¦Á and Beyond: Rapid Mitochondrial Dysfunction Mediates TNF-¦Á-Induced Neurotoxicity. other hsa-mir-125b "Carcinoma, Hepatocellular" 28654261 Astragalin Reduces Hexokinase 2 through Increasing miR-125b to Inhibit the Proliferation of Hepatocellular Carcinoma Cells in Vitro and in Vivo. other hsa-mir-96 "Carcinoma, Lung, Non-Small-Cell" 28656287 "Identification and characterization of miR-96, a potential biomarker of NSCLC, through bioinformatic analysis." other hsa-mir-34a Neoplasms [unspecific] 28657476 Comparison of Peptide- and Lipid-Based Delivery of miR-34a-5p Mimic into PPC-1 Cells. other hsa-mir-23a Vascular Disease [unspecific] 28662151 Bone marrow mesenchymal stem cell-derived vascular endothelial growth factor attenuates cardiac apoptosis via regulation of cardiac miRNA-23a and miRNA-92a in a rat model of myocardial infarction. other hsa-mir-92a Vascular Disease [unspecific] 28662151 Bone marrow mesenchymal stem cell-derived vascular endothelial growth factor attenuates cardiac apoptosis via regulation of cardiac miRNA-23a and miRNA-92a in a rat model of myocardial infarction. other hsa-mir-155 Systemic Lupus Erythematosus 28665018 "MiR-155*, miR-34b and miR-34a levels in T lymphocytes and corresponding MVs were deregulated in SLE when compared to healthy individuals" other hsa-mir-34a Systemic Lupus Erythematosus 28665018 "MiR-155*, miR-34b and miR-34a levels in T lymphocytes and corresponding MVs were deregulated in SLE when compared to healthy individuals" other hsa-mir-34b Systemic Lupus Erythematosus 28665018 "MiR-155*, miR-34b and miR-34a levels in T lymphocytes and corresponding MVs were deregulated in SLE when compared to healthy individuals" other hsa-mir-155 "Carcinoma, Hepatocellular" 28670383 "MiR-155 up-regulated by TGF-¦Â promotes epithelial-mesenchymal transition, invasion and metastasis of human hepatocellular carcinoma cells in vitro." other hsa-mir-16 Neoplasms [unspecific] 28670496 Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators. other hsa-mir-1 Sepsis 28673002 IGF-1 may predict the severity and outcome of patients with sepsis and be associated with microRNA-1 level changes. other hsa-mir-21 Atherosclerosis 28674080 "Macrophage deficiency of miR-21 promotes apoptosis, plaque necrosis, and vascular inflammation during atherogenesis." other hsa-mir-200c Lung Neoplasms 28675952 A novel fine tuning scheme of miR-200c in modulating lung cell redox homeostasis. other hsa-let-7b Glioblastoma 28677425 IKBKE promotes glioblastoma progression by establishing the regulatory feedback loop of IKBKE/YAP1/miR-Let-7b/i. other hsa-mir-200a "Squamous Cell Carcinoma, Head and Neck" 28677748 Salivary miR-93 and miR-200a as post-radiotherapy biomarkers in head and neck squamous cell carcinoma. other hsa-mir-93 "Squamous Cell Carcinoma, Head and Neck" 28677748 Salivary miR-93 and miR-200a as post-radiotherapy biomarkers in head and neck squamous cell carcinoma. other hsa-mir-126 Atherosclerosis 28678312 Identification of miRNAs as atherosclerosis biomarkers and functional role of miR-126 in atherosclerosis progression through MAPK signalling pathway. other hsa-mir-122a "Carcinoma, Hepatocellular" 28686599 Flux balance analysis predicts Warburg-like effects of mouse hepatocyte deficient in miR-122a. other hsa-mir-29a Bladder Neoplasms 28687357 Circular RNA MYLK as a competing endogenous RNA promotes bladder cancer progression through modulating VEGFA/VEGFR2 signaling pathway. other hsa-let-7a "Carcinoma, Hepatocellular" 28691642 XIAP 3'-untranslated region serves as a competitor for HMGA2 by arresting endogenous let-7a-5p in human hepatocellular carcinoma. other hsa-mir-125b "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 28693195 MicroRNA-125b targeted STAT3 to inhibit laryngeal squamous cell carcinoma cell growth and motility. other hsa-mir-92b Ovarian Neoplasms 28693226 Screening of potentially crucial genes and regulatory factors involved in epithelial ovarian cancer using microarray analysis. other hsa-mir-92b Colorectal Carcinoma 28693229 MicroRNAs as outcome predictors in patients with metastatic colorectal cancer treated with bevacizumab in combination with FOLFOX. other hsa-mir-106a Colorectal Carcinoma 28693239 Biological effects and clinical characteristics of microRNA-106a in human colorectal cancer other hsa-mir-296 Nasal Cavity Inverting Papilloma 28693263 Role of microRNA-296-3p in the malignant transformation of sinonasal inverted papilloma. other hsa-mir-210 Prostate Neoplasms 28693582 Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-¦ÊB signaling pathway. other hsa-mir-24 Blood Coagulation Disorders 28694557 Overexpression of miR-24 Is Involved in the Formation of Hypocoagulation State after Severe Trauma by Inhibiting the Synthesis of Coagulation Factor X. other hsa-mir-92a Cardiovascular Diseases [unspecific] 28696247 MicroRNA-92a Mediates Endothelial Dysfunction in CKD. other hsa-mir-548f Leukemia 28698179 A Novel Regulatory Mechanism of Smooth Muscle ¦Á-Actin Expression by NRG-1/circACTA2/miR-548f-5p Axis. other hsa-mir-27b "Diabetes Mellitus, Type 2" 28698281 MiR-27b augments bone marrow progenitor cell survival via suppressing the mitochondrial apoptotic pathway in Type 2 diabetes. other hsa-mir-21 Myocardial Infarction 28699517 Circadian MicroRNAs in Cardioprotection. other hsa-mir-29a Breast Neoplasms 28701793 The miR-29 transcriptome in endocrine-sensitive and resistant breast cancer cells. other hsa-mir-21 "Carcinoma, Lung" 28705115 MicroRNA-21 versus microRNA-34: Lung cancer promoting and inhibitory microRNAs analysed in silico and in vitro and their clinical impact. other hsa-mir-34 "Carcinoma, Lung" 28705115 MicroRNA-21 versus microRNA-34: Lung cancer promoting and inhibitory microRNAs analysed in silico and in vitro and their clinical impact. other hsa-mir-21 Vascular Disease [unspecific] 28707876 Fluorescence Light-Up Biosensor for MicroRNA Based on the Distance-Dependent Photoinduced Electron Transfer. other hsa-mir-34a Ischemia-Reperfusion Injury 28709867 Attenuation of the hypoxia-induced miR-34a protects cardiomyocytes through maintenance of glucose metabolism. other hsa-mir-375 Oral Neoplasms 28713923 The differential regulation of microRNAs is associated with oral cancer other hsa-mir-204 Ischemia-Reperfusion Injury 28714326 "miR-204 inhibitor upregulated the activity and expression of RAP2C, while miR-204 mimic played the opposite role" other hsa-mir-21 "Carcinoma, Renal Cell" 28714373 Targeting miR-21 decreases expression of multi-drug resistant genes and promotes chemosensitivity of renal carcinoma. other hsa-mir-424 Early-Stage Colon Adenocarcinoma 28714374 Screening key genes and miRNAs in early-stage colon adenocarcinoma by RNA-sequencing. other hsa-mir-548am Early-Stage Colon Adenocarcinoma 28714374 Screening key genes and miRNAs in early-stage colon adenocarcinoma by RNA-sequencing. other hsa-mir-548c Early-Stage Colon Adenocarcinoma 28714374 Screening key genes and miRNAs in early-stage colon adenocarcinoma by RNA-sequencing. other hsa-mir-548i Early-Stage Colon Adenocarcinoma 28714374 Screening key genes and miRNAs in early-stage colon adenocarcinoma by RNA-sequencing. other hsa-mir-661 "Carcinoma, Lung, Non-Small-Cell" 28716024 MiR-661 promotes tumor invasion and metastasis by directly inhibiting RB1 in non small cell lung cancer other hsa-mir-613 Glioblastoma 28718378 MicroRNA-613 is downregulated in HCMV-positive glioblastoma and inhibits tumour progression by targeting arginase-2. other hsa-mir-29b Myocardial Infarction 28722488 Berberine promotes ischemia-induced angiogenesis in mice heart via upregulation of microRNA-29b. other hsa-mir-155 Glioma 28724215 Melatonin inhibits proliferation and invasion via repression of miRNA-155 in glioma cells. other hsa-mir-21 Glioblastoma 28727188 we highlighted utilization of miR-21 as diagnostic and therapeutic biomarker for GBM patients other hsa-mir-30a "Carcinoma, Hepatocellular" 28732393 MicroRNA-30a suppresses tumor progression by blocking Ras/Raf/MEK/ERK signaling pathway in hepatocellular carcinoma other hsa-mir-18a Endomyocardial Fibrosis 28733035 MiR-18a-5p inhibits endothelial-mesenchymal transition and cardiac fibrosis through the Notch2 pathway. other hsa-let-7 Neuroinflammation 28737113 "Key pro-inflammatory ( miR-155, miR-27b, miR-326), anti-inflammatory ( miR-124, miR-146a, miR-21, miR-223), and mixed immunomodulatory ( let-7 family) miRNAs regulate neuroinflammation in various pathologies" other hsa-mir-124 Neuroinflammation 28737113 "Key pro-inflammatory ( miR-155, miR-27b, miR-326), anti-inflammatory ( miR-124, miR-146a, miR-21, miR-223), and mixed immunomodulatory ( let-7 family) miRNAs regulate neuroinflammation in various pathologies" other hsa-mir-146a Neuroinflammation 28737113 "Key pro-inflammatory ( miR-155, miR-27b, miR-326), anti-inflammatory ( miR-124, miR-146a, miR-21, miR-223), and mixed immunomodulatory ( let-7 family) miRNAs regulate neuroinflammation in various pathologies" other hsa-mir-155 Neuroinflammation 28737113 "Key pro-inflammatory ( miR-155, miR-27b, miR-326), anti-inflammatory ( miR-124, miR-146a, miR-21, miR-223), and mixed immunomodulatory ( let-7 family) miRNAs regulate neuroinflammation in various pathologies" other hsa-mir-21 Neuroinflammation 28737113 "Key pro-inflammatory ( miR-155, miR-27b, miR-326), anti-inflammatory ( miR-124, miR-146a, miR-21, miR-223), and mixed immunomodulatory ( let-7 family) miRNAs regulate neuroinflammation in various pathologies" other hsa-mir-223 Neuroinflammation 28737113 "Key pro-inflammatory ( miR-155, miR-27b, miR-326), anti-inflammatory ( miR-124, miR-146a, miR-21, miR-223), and mixed immunomodulatory ( let-7 family) miRNAs regulate neuroinflammation in various pathologies" other hsa-mir-27b Neuroinflammation 28737113 "Key pro-inflammatory ( miR-155, miR-27b, miR-326), anti-inflammatory ( miR-124, miR-146a, miR-21, miR-223), and mixed immunomodulatory ( let-7 family) miRNAs regulate neuroinflammation in various pathologies" other hsa-mir-326 Neuroinflammation 28737113 "Key pro-inflammatory ( miR-155, miR-27b, miR-326), anti-inflammatory ( miR-124, miR-146a, miR-21, miR-223), and mixed immunomodulatory ( let-7 family) miRNAs regulate neuroinflammation in various pathologies" other hsa-mir-141 "Carcinoma, Colon" 28739727 miR-141 Inhibits Proliferation and Migration of Colorectal Cancer SW480 Cells. other hsa-mir-96 "Adenocarcinoma, Colon" 28742206 Bioinformatics analysis of RNA-seq data revealed critical genes in colon adenocarcinoma other hsa-mir-200c Colorectal Carcinoma 28745318 Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity. other hsa-mir-34a Hearing Loss 28756190 miR-34a/Bcl-2 signaling pathway contributes to age-related hearing loss by modulating hair cell apoptosis. other hsa-mir-30a Medulloblastoma 28757413 "Restoration of miR-30a expression inhibits growth, tumorigenicity of medulloblastoma cells accompanied by autophagy inhibition." other hsa-mir-34a Melanoma 28759238 Ternary Nanoparticles with a Sheddable Shell Efficiently Deliver MicroRNA-34a against CD44-Positive Melanoma. other hsa-mir-375 "Carcinoma, Hepatocellular" 28769563 Delivery of miR-375 and doxorubicin hydrochloride by lipid-coated hollow mesoporous silica nanoparticles to overcome multiple drug resistance in hepatocellular carcinoma other hsa-mir-16 "Carcinoma, Hepatocellular" 28770611 Clinical significance of miRNA-autophagy transcript expression in patients with hepatocellular carcinoma other hsa-mir-221 Bladder Neoplasms 28770966 Inhibition of miR-221 influences bladder cancer cell proliferation and apoptosis. other hsa-mir-146a Ischemia-Reperfusion Injury 28771774 MiR-146a protects small intestine against ischemia/reperfusion injury by down-regulating TLR4/TRAF6/NF-¦ÊB pathway. other hsa-mir-1274a Neoplasms [unspecific] 28774834 "the present review discussed the role of FoxOs in association with miRNAs such as miR-182, miR-135b, miR-499-5p, miR-1274a, miR-150, miR-34b/c and miR-625" other hsa-mir-135b Neoplasms [unspecific] 28774834 "the present review discussed the role of FoxOs in association with miRNAs such as miR-182, miR-135b, miR-499-5p, miR-1274a, miR-150, miR-34b/c and miR-623" other hsa-mir-150 Neoplasms [unspecific] 28774834 "the present review discussed the role of FoxOs in association with miRNAs such as miR-182, miR-135b, miR-499-5p, miR-1274a, miR-150, miR-34b/c and miR-626" other hsa-mir-182 Neoplasms [unspecific] 28774834 "the present review discussed the role of FoxOs in association with miRNAs such as miR-182, miR-135b, miR-499-5p, miR-1274a, miR-150, miR-34b/c and miR-622" other hsa-mir-34b Neoplasms [unspecific] 28774834 "the present review discussed the role of FoxOs in association with miRNAs such as miR-182, miR-135b, miR-499-5p, miR-1274a, miR-150, miR-34b/c and miR-627" other hsa-mir-34c Neoplasms [unspecific] 28774834 "the present review discussed the role of FoxOs in association with miRNAs such as miR-182, miR-135b, miR-499-5p, miR-1274a, miR-150, miR-34b/c and miR-628" other hsa-mir-499 Neoplasms [unspecific] 28774834 "the present review discussed the role of FoxOs in association with miRNAs such as miR-182, miR-135b, miR-499-5p, miR-1274a, miR-150, miR-34b/c and miR-624" other hsa-mir-622 Neoplasms [unspecific] 28774834 "the present review discussed the role of FoxOs in association with miRNAs such as miR-182, miR-135b, miR-499-5p, miR-1274a, miR-150, miR-34b/c and miR-629" other hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 28783166 Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model. other hsa-mir-26a "Leukemia, Lymphocytic, Chronic, B-Cell" 28783166 Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model. other hsa-mir-33b Asthma 28785038 Inhibition of airway inflammation in a cockroach allergen model of asthma by agonists of miRNA-33b. other hsa-mir-20a Ovarian Neoplasms 28789409 MicroRNA-20a contributes to cisplatin-resistance and migration of OVCAR3 ovarian cancer cell line. other hsa-mir-29c Lung Fibrosis 28799781 MicroRNA-29c Prevents Pulmonary Fibrosis by Regulating Epithelial Cell Renewal and Apoptosis. other hsa-mir-223 Traumatic Brain Injury 28804446 Induction of miR-155 after Brain Injury Promotes Type 1 Interferon and has a Neuroprotective Effect. other hsa-let-7a Multiple Myeloma 28808676 "a thymidine-kinase-deleted let-7a-regulated vaccinia virus was safe and effective for mice, warranting clinical trials in humans" other hsa-mir-1275 "Carcinoma, Hepatocellular" 28817968 Destabilizing the interplay between miR-1275 and IGF2BPs by Tamarix articulata and quercetin in hepatocellular carcinoma. other hsa-mir-18a Pancreatic Neoplasms 28822990 ¦ÁM and ¦ÃM can induce apoptosis and autophagy in pancreatic cancer cells and that their anti-cancer effect is likely to be associated with miR-18a other hsa-mir-222 "Leukemia, Lymphocytic, Chronic, B-Cell" 28824233 Inhibition of MicroRNA miR-222 with LNA Inhibitor Can Reduce Cell Proliferation in B Chronic Lymphoblastic Leukemia other hsa-mir-155 Neuronal Apoptosis-Related Diseases 28831740 "Expression of miR-155 associated with Toll-like receptors 3, 7, and 9 transcription in the olfactory bulbs of cattle naturally infected with BHV5." other hsa-mir-145 Prostate Neoplasms 28843521 Curcumin suppresses proliferation and in vitro invasion of human prostate cancer stem cells by ceRNA effect of miR-145 and lncRNA-ROR. other hsa-mir-122 Chronic Hepatitis C 28844749 Immune responses in DAA treated chronic hepatitis C patients with and without prior RG-101 dosing. other hsa-mir-195 "Carcinoma, Lung, Non-Small-Cell" 28848163 Knockdown of Lncrna PVT1 Enhances Radiosensitivity in Non-Small Cell Lung Cancer by Sponging Mir-195. other hsa-mir-140 Autism Spectrum Disorder 28848387 "Expression and Regulatory Network Analysis of miR-140-3p, a New Potential Serum Biomarker for Autism Spectrum Disorder." other hsa-mir-205 Heart Failure 28849082 Short?term vagus nerve stimulation reduces myocardial apoptosis by downregulating microRNA?205 in rats with chronic heart failure. other hsa-mir-146a Graft-Versus-Host Disease 28853768 Systemic Treatment with a miR-146a Mimic Suppresses Endotoxin Sensitivity and Partially Protects Mice from the Progression of Acute Graft-versus-Host Disease. other hsa-mir-30a Stroke 28854438 Down-Regulation of Lncrna MALAT1 Attenuates Neuronal Cell Death Through Suppressing Beclin1-Dependent Autophagy by Regulating Mir-30a in Cerebral Ischemic Stroke. other hsa-mir-222 Melanoma 28858076 KIT and mir-222 might be key genomic contributors toward the clinical differences observed other hsa-mir-214 Sepsis 28858140 miRNA-214 Protects Sepsis-Induced Myocardial Injury. other hsa-mir-223 Chronic Hepatitis C 28864162 "Treatment-Induced Viral Cure of Hepatitis C Virus-Infected Patients Involves a Dynamic Interplay among three Important Molecular Players in Lipid Homeostasis: Circulating microRNA (miR)-24, miR-223, and Proprotein Convertase Subtilisin/Kexin Type 9." other hsa-mir-24 Chronic Hepatitis C 28864162 "Treatment-Induced Viral Cure of Hepatitis C Virus-Infected Patients Involves a Dynamic Interplay among three Important Molecular Players in Lipid Homeostasis: Circulating microRNA (miR)-24, miR-223, and Proprotein Convertase Subtilisin/Kexin Type 9." other hsa-mir-31 Myocardial Infarction 28865712 MicroRNA-31 promotes adverse cardiac remodeling and dysfunction in ischemic heart disease. other hsa-mir-29b Lung Neoplasms 28869603 "DNMT1 and KIT form a positive regulatory loop, in which ectopic DNMT1 expression increases, whereas targeted DNMT1 depletion abrogates KIT signaling cascade through Sp1/miR-29b network" other hsa-mir-143 Infection [unspecific] 28870451 MicroRNA-based transcriptomic responses of Atlantic salmon during infection by the intracellular bacterium Piscirickettsia salmonis. other hsa-mir-181 Infection [unspecific] 28870451 MicroRNA-based transcriptomic responses of Atlantic salmon during infection by the intracellular bacterium Piscirickettsia salmonis. other hsa-mir-21 Infection [unspecific] 28870451 MicroRNA-based transcriptomic responses of Atlantic salmon during infection by the intracellular bacterium Piscirickettsia salmonis. other hsa-mir-194 Rectum Adenocarcinoma 28870889 miR-194 as predictive biomarker of responsiveness to neoadjuvant chemoradiotherapy in patients with locally advanced rectal adenocarcinoma. other hsa-mir-449a Colon Neoplasms 28878284 MicroRNA-449a deficiency promotes colon carcinogenesis. other hsa-mir-494 Ischemic Diseases [unspecific] 28880896 Extract of Spatholobus suberctus Dunn ameliorates ischemia-induced injury by targeting miR-494. other hsa-mir-200b Retinal Vascular Disease 28882646 Protective effect of miR-200b/c by inhibiting vasohibin-2 in human retinal microvascular endothelial cells. other hsa-mir-200c Retinal Vascular Disease 28882646 Protective effect of miR-200b/c by inhibiting vasohibin-2 in human retinal microvascular endothelial cells. other hsa-mir-146a Atherosclerosis 28882869 "EV-derived miRNAs from atherogenic macrophages, in particular miR-146a, may accelerate the development of atherosclerosis by decreasing cell migration and promoting macrophage entrapment in the vessel wall" other hsa-mir-193b Liposarcoma 28882999 miR-193b-Regulated Signaling Networks Serve as Tumor Suppressors in Liposarcoma and Promote Adipogenesis in Adipose-Derived Stem Cells. other hsa-mir-29 Alveolar Rhabdomyosarcoma 28883017 "the NF¦ÊB-YY1-miR-29 regulatory circuit is dysregulated, resulting in repression of miR-29 and loss of the associated tumor suppressor activity" other hsa-mir-15a Heart Valve Disease 28888871 Interplay of mitochondria apoptosis regulatory factors and microRNAs in valvular heart disease. other hsa-mir-29a Heart Valve Disease 28888871 Interplay of mitochondria apoptosis regulatory factors and microRNAs in valvular heart disease. other hsa-mir-1 Myocardial Infarction 28894747 "regulatory effects on miR-1, miR-133, Cx43, and Cx45 might be a possible mechanism of WXKL in the treatment of MI at the gene level" other hsa-mir-133 Myocardial Infarction 28894747 "regulatory effects on miR-1, miR-133, Cx43, and Cx45 might be a possible mechanism of WXKL in the treatment of MI at the gene level" other hsa-mir-200b Colorectal Carcinoma 28899657 HIF-1¦Á/Ascl2/miR-200b regulatory feedback circuit modulated the epithelial-mesenchymal transition (EMT) in colorectal cancer cells. other hsa-mir-17 Glioblastoma 28903422 The E2F1-regulated miR-17/92 cluster and its analogs are shown to be highly expressed in proneural GBM and in GSC lines other hsa-mir-18 Glioblastoma 28903422 The E2F1-regulated miR-17/92 cluster and its analogs are shown to be highly expressed in proneural GBM and in GSC lines other hsa-mir-19a Glioblastoma 28903422 The E2F1-regulated miR-17/92 cluster and its analogs are shown to be highly expressed in proneural GBM and in GSC lines other hsa-mir-19b-1 Glioblastoma 28903422 The E2F1-regulated miR-17/92 cluster and its analogs are shown to be highly expressed in proneural GBM and in GSC lines other hsa-mir-20a Glioblastoma 28903422 The E2F1-regulated miR-17/92 cluster and its analogs are shown to be highly expressed in proneural GBM and in GSC lines other hsa-mir-92-1 Glioblastoma 28903422 The E2F1-regulated miR-17/92 cluster and its analogs are shown to be highly expressed in proneural GBM and in GSC lines other hsa-mir-17 "Carcinoma, Hepatocellular" 28904393 MicroRNA pharmacogenomics based integrated model of miR-17-92 cluster in sorafenib resistant HCC cells reveals a strategy to forestall drug resistance. other hsa-mir-18 "Carcinoma, Hepatocellular" 28904393 MicroRNA pharmacogenomics based integrated model of miR-17-92 cluster in sorafenib resistant HCC cells reveals a strategy to forestall drug resistance. other hsa-mir-19a "Carcinoma, Hepatocellular" 28904393 MicroRNA pharmacogenomics based integrated model of miR-17-92 cluster in sorafenib resistant HCC cells reveals a strategy to forestall drug resistance. other hsa-mir-19b-1 "Carcinoma, Hepatocellular" 28904393 MicroRNA pharmacogenomics based integrated model of miR-17-92 cluster in sorafenib resistant HCC cells reveals a strategy to forestall drug resistance. other hsa-mir-20a "Carcinoma, Hepatocellular" 28904393 MicroRNA pharmacogenomics based integrated model of miR-17-92 cluster in sorafenib resistant HCC cells reveals a strategy to forestall drug resistance. other hsa-mir-92-1 "Carcinoma, Hepatocellular" 28904393 MicroRNA pharmacogenomics based integrated model of miR-17-92 cluster in sorafenib resistant HCC cells reveals a strategy to forestall drug resistance. other hsa-mir-155 Neoplasms [unspecific] 28912267 Antitumor immunity is defective in T cell-specific microRNA-155-deficient mice and is rescued by immune checkpoint blockade. other hsa-mir-124 Alzheimer Disease 28912710 "A¦Â downregulated miR-155 and miR-124, and reduced the CD11b+ subpopulation in 2 DIV microglia" other hsa-mir-155 Alzheimer Disease 28912710 "A¦Â downregulated miR-155 and miR-124, and reduced the CD11b+ subpopulation in 2 DIV microglia" other hsa-mir-375 "Carcinoma, Hepatocellular" 28915706 The role of autophagy in hepatocellular carcinoma: friend or foe. other hsa-mir-31 Mesothelioma 28918032 MicroRNA-31 Regulates Chemosensitivity in Malignant Pleural Mesothelioma. other hsa-mir-146a Lymphoma 28918474 Induction of Immunogenic Cell Death in Lymphoma Cells by Wharton's Jelly Mesenchymal Stem Cell Conditioned Medium. other hsa-mir-222 "Squamous Cell Carcinoma, Skin or Unspecific" 28925390 Alterations of microRNAs throughout the malignant evolution of cutaneous squamous cell carcinoma: the role of miR-497 in epithelial to mesenchymal transition of keratinocytes. other hsa-mir-7 Colorectal Carcinoma 28929494 CRHR2/Ucn2 signaling is a novel regulator of miR-7/YY1/Fas circuitry contributing to reversal of colorectal cancer cell resistance to Fas-mediated apoptosis. other hsa-mir-223 Lung Injury [unspecific] 28931657 Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice. other hsa-mir-335 Neoplasms [unspecific] 28932769 MicroRNA expression in a phosphaturic mesenchymal tumour. other hsa-mir-143 Breast Neoplasms 28933584 Circular RNA hsa_circ_0001982 Promotes Breast Cancer Cell Carcinogenesis Through Decreasing miR-143. other hsa-mir-181b Sepsis 28934717 the CCAAT enhancer-binding protein C/EBP¦Â activates microRNA (miR)-21 and miR-181b expressions other hsa-mir-21 Sepsis 28934717 the CCAAT enhancer-binding protein C/EBP¦Â activates microRNA (miR)-21 and miR-181b expressions other hsa-mir-221 Melanoma 28936555 Resveratrol suppresses melanoma by inhibiting NF-¦ÊB/miR-221 and inducing TFG expression. other hsa-mir-125b Bladder Neoplasms 28938585 The trophoblast cell surface antigen 2 and miR-125b axis in urothelial bladder cancer. other hsa-let-7d "Squamous Cell Carcinoma, Head and Neck" 28941018 "The available literature supports differential expression of both microRNAs and long non-coding RNAs, which include oncogenic ncRNAs (miR-21, miR-31, miR-155, miR-211, HOTAIR, and MALAT1) and tumor suppressor ncRNAs (let7d, miR-17, miR-375, miR-139, and MEG3) in HPV+ve HNSCC tumors as compared to HPV-ve tumors and they have distinct role in the pathophysiology of these two types of HNSCCs" other hsa-mir-139 "Squamous Cell Carcinoma, Head and Neck" 28941018 "The available literature supports differential expression of both microRNAs and long non-coding RNAs, which include oncogenic ncRNAs (miR-21, miR-31, miR-155, miR-211, HOTAIR, and MALAT1) and tumor suppressor ncRNAs (let7d, miR-17, miR-375, miR-139, and MEG3) in HPV+ve HNSCC tumors as compared to HPV-ve tumors and they have distinct role in the pathophysiology of these two types of HNSCCs" other hsa-mir-155 "Squamous Cell Carcinoma, Head and Neck" 28941018 "The available literature supports differential expression of both microRNAs and long non-coding RNAs, which include oncogenic ncRNAs (miR-21, miR-31, miR-155, miR-211, HOTAIR, and MALAT1) and tumor suppressor ncRNAs (let7d, miR-17, miR-375, miR-139, and MEG3) in HPV+ve HNSCC tumors as compared to HPV-ve tumors and they have distinct role in the pathophysiology of these two types of HNSCCs" other hsa-mir-17 "Squamous Cell Carcinoma, Head and Neck" 28941018 "The available literature supports differential expression of both microRNAs and long non-coding RNAs, which include oncogenic ncRNAs (miR-21, miR-31, miR-155, miR-211, HOTAIR, and MALAT1) and tumor suppressor ncRNAs (let7d, miR-17, miR-375, miR-139, and MEG3) in HPV+ve HNSCC tumors as compared to HPV-ve tumors and they have distinct role in the pathophysiology of these two types of HNSCCs" other hsa-mir-21 "Squamous Cell Carcinoma, Head and Neck" 28941018 "The available literature supports differential expression of both microRNAs and long non-coding RNAs, which include oncogenic ncRNAs (miR-21, miR-31, miR-155, miR-211, HOTAIR, and MALAT1) and tumor suppressor ncRNAs (let7d, miR-17, miR-375, miR-139, and MEG3) in HPV+ve HNSCC tumors as compared to HPV-ve tumors and they have distinct role in the pathophysiology of these two types of HNSCCs" other hsa-mir-211 "Squamous Cell Carcinoma, Head and Neck" 28941018 "The available literature supports differential expression of both microRNAs and long non-coding RNAs, which include oncogenic ncRNAs (miR-21, miR-31, miR-155, miR-211, HOTAIR, and MALAT1) and tumor suppressor ncRNAs (let7d, miR-17, miR-375, miR-139, and MEG3) in HPV+ve HNSCC tumors as compared to HPV-ve tumors and they have distinct role in the pathophysiology of these two types of HNSCCs" other hsa-mir-31 "Squamous Cell Carcinoma, Head and Neck" 28941018 "The available literature supports differential expression of both microRNAs and long non-coding RNAs, which include oncogenic ncRNAs (miR-21, miR-31, miR-155, miR-211, HOTAIR, and MALAT1) and tumor suppressor ncRNAs (let7d, miR-17, miR-375, miR-139, and MEG3) in HPV+ve HNSCC tumors as compared to HPV-ve tumors and they have distinct role in the pathophysiology of these two types of HNSCCs" other hsa-mir-375 "Squamous Cell Carcinoma, Head and Neck" 28941018 "The available literature supports differential expression of both microRNAs and long non-coding RNAs, which include oncogenic ncRNAs (miR-21, miR-31, miR-155, miR-211, HOTAIR, and MALAT1) and tumor suppressor ncRNAs (let7d, miR-17, miR-375, miR-139, and MEG3) in HPV+ve HNSCC tumors as compared to HPV-ve tumors and they have distinct role in the pathophysiology of these two types of HNSCCs" other hsa-mir-130a Coronary Artery Disease 28947970 Circular RNAs promote TRPM3 expression by inhibiting hsa-miR-130a-3p in coronary artery disease patients. other hsa-mir-210 Myocardial Infarction 28948298 "MicroRNA-210-mediated proliferation, survival, and angiogenesis promote cardiac repair post myocardial infarction in rodents." other hsa-mir-182 Glioma 28956430 The feasibility of the method for sensitive determination of miRNA-182 and miRNA-381 from serum samples of glioma patients at different stages was demonstrated other hsa-mir-381 Glioma 28956430 The feasibility of the method for sensitive determination of miRNA-182 and miRNA-381 from serum samples of glioma patients at different stages was demonstrated other hsa-mir-10a "Carcinoma, Hepatocellular" 28958640 "our data showed potential role of miR-10a, miR-30e, miR-215, miR-125b and miR-148a as important mediators in HCC progression" other hsa-mir-125b "Carcinoma, Hepatocellular" 28958640 "our data showed potential role of miR-10a, miR-30e, miR-215, miR-125b and miR-148a as important mediators in HCC progression" other hsa-mir-148a "Carcinoma, Hepatocellular" 28958640 "our data showed potential role of miR-10a, miR-30e, miR-215, miR-125b and miR-148a as important mediators in HCC progression" other hsa-mir-215 "Carcinoma, Hepatocellular" 28958640 "our data showed potential role of miR-10a, miR-30e, miR-215, miR-125b and miR-148a as important mediators in HCC progression" other hsa-mir-30e "Carcinoma, Hepatocellular" 28958640 "our data showed potential role of miR-10a, miR-30e, miR-215, miR-125b and miR-148a as important mediators in HCC progression" other hsa-mir-138 "Squamous Cell Carcinoma, Oral" 28962163 "miR-138 is able to inhibit the proliferation, migration and invasion of OSCC cell lines" other hsa-mir-675 Dental Enamel Hypoplasia 28963438 DLX3 promotes bone marrow mesenchymal stem cell proliferation through H19/miR-675 axis. other hsa-mir-16 Lymphoma 28976967 A viral Sm-class RNA base-pairs with mRNAs and recruits microRNAs to inhibit apoptosis. other hsa-mir-1224 Leukemia 28977780 a similar expression pattern of hsa-miR-1224-3p and hsa-miR-21 were observed in urine samples collected from human leukemia patients preconditioned with TBI other hsa-mir-21 Leukemia 28977780 a similar expression pattern of hsa-miR-1224-3p and hsa-miR-21 were observed in urine samples collected from human leukemia patients preconditioned with TBI other hsa-mir-30d Mesothelioma 28979837 miR-30d is related to asbestos exposure and inhibits migration and invasion in NCI-H2452 cells. other hsa-mir-145 Myocardial Infarction 28980287 Inducible miR-145 expression by HIF-1a protects cardiomyocytes against apoptosis via regulating SGK1 in simulated myocardial infarction hypoxic microenvironment. other hsa-mir-1 Cardiomegaly 28985746 Porcine model of progressive cardiac hypertrophy and fibrosis with secondary postcapillary pulmonary hypertension. other hsa-mir-29a Cardiomegaly 28985746 Porcine model of progressive cardiac hypertrophy and fibrosis with secondary postcapillary pulmonary hypertension. other hsa-mir-7 "Leukemia, Myeloid, Chronic" 28986256 MicroRNA-7 inhibits cell proliferation of chronic myeloid leukemia and sensitizes it to imatinib in?vitro. other hsa-mir-433 Parkinson Disease 28986288 Linking down-regulation of miRNA-7 and miRNA-433 with ¦Á-synuclein overexpression and risk of idiopathic Parkinson's disease. other hsa-mir-7 Parkinson Disease 28986288 Linking down-regulation of miRNA-7 and miRNA-433 with ¦Á-synuclein overexpression and risk of idiopathic Parkinson's disease. other hsa-mir-146a Gastric Neoplasms 28987948 MiR-146a functions as a small silent player in gastric cancer. other hsa-mir-10b Neoplasms [unspecific] 28989695 Simultaneous visualization of the subfemtomolar expression of microRNA and microRNA target gene using HILO microscopy. other hsa-mir-21 Glioblastoma 29023168 Development and characterization of cationic solid lipid nanoparticles for co-delivery of pemetrexed and miR-21 antisense oligonucleotide to glioblastoma cells. other hsa-mir-132 Heart Failure 29027324 Circulating microRNA-132 levels improve risk prediction for heart failure hospitalization in patients with chronic heart failure. other hsa-mir-200c Neoplasms [unspecific] 29029445 MicroRNA-200c increases radiosensitivity of human cancer cells with activated EGFR-associated signaling. other hsa-mir-192 "Diabetes Mellitus, Type 2" 29040025 "Lower concentrations of miR-192 and miR-375 were also found, which correlated positively with HOMA-IR" other hsa-mir-375 "Diabetes Mellitus, Type 2" 29040025 "Lower concentrations of miR-192 and miR-375 were also found, which correlated positively with HOMA-IR" other hsa-mir-181a Melanoma 29041990 Piceatannol induced apoptosis through up-regulation of microRNA-181a in melanoma cells. other hsa-mir-326 Multiple Sclerosis 29043654 "Evaluation of Selected MicroRNAs Expression in Remission Phase of Multiple Sclerosis and Their Potential Link to Cognition, Depression, and Disability." other hsa-mir-181b Cystic Fibrosis 29044225 microRNA-181b is increased in cystic fibrosis cells and impairs lipoxin A4 receptor-dependent mechanisms of inflammation resolution and antimicrobial defense. other hsa-mir-27b Brain Disease [unspecific] 29050310 MicroRNA-27b inhibition promotes Nrf2/ARE pathway activation and alleviates intracerebral hemorrhage-induced brain injury other hsa-mir-206 Myocardial Infarction 29055786 Carbon monoxide releasing molecule improves structural and functional cardiac recovery after myocardial injury. other hsa-mir-155 "Carcinoma, Renal Cell" 29056573 Noncoding RNA Expression and Targeted Next-Generation Sequencing Distinguish Tubulocystic Renal Cell Carcinoma (TC-RCC) from Other Renal Neoplasms. other hsa-mir-21 Melanoma 29058784 MicroRNA-21 antisense oligonucleotide improves the sensitivity of A375 human melanoma cell to Cisplatin other hsa-mir-30a "Carcinoma, Hepatocellular" 29061507 MicroRNA-30a suppresses autophagy-mediated anoikis resistance and metastasis in hepatocellular carcinoma. other hsa-mir-22 Myocardial Infarction 29063105 miR-22 plays critical roles in MI and subsequent cardiac remodeling other hsa-mir-375 Colorectal Carcinoma 29068474 The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer. other hsa-let-7i Infection [unspecific] 29069656 Cyclosporine A Induces MicroRNAs Controlling Innate Immunity during Renal Bacterial Infection. other hsa-mir-148a Ovarian Neoplasms 29069830 "The selected signature composed by VAT1L, CALR, LINC01456, RP11-484L8.1, MIR196A1 and MIR148A, separated the training group patients into high-risk or low-risk subgroup with significantly different survival time" other hsa-mir-196a-1 Ovarian Neoplasms 29069830 "The selected signature composed by VAT1L, CALR, LINC01456, RP11-484L8.1, MIR196A1 and MIR148A, separated the training group patients into high-risk or low-risk subgroup with significantly different survival time" other hsa-mir-21 "Carcinoma, Renal Cell" 29070781 Cordycepin induces apoptotic cell death and inhibits cell migration in renal cell carcinoma via regulation of microRNA-21 and PTEN phosphatase. other hsa-mir-124 Neuroblastoma 29073265 MiRNA-124 is a link between measles virus persistent infection and cell division of human neuroblastoma cells. other hsa-mir-9 "Squamous Cell Carcinoma, Oral" 29073835 miR-9 induces cell arrest and apoptosis of oral squamous cell carcinoma via CDK 4/6 pathway. other hsa-mir-155 Neuroinflammation 29079998 Role of 3-Acetyl-11-Keto-Beta-Boswellic Acid in Counteracting LPS-Induced Neuroinflammation via Modulation of miRNA-155. other hsa-mir-378 Glioblastoma 29081036 MicroRNA-378 enhances radiation response in ectopic and orthotopic implantation models of glioblastoma. other hsa-mir-122 Chronic Hepatitis C 29084265 miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence. other hsa-mir-15a Laryngeal Neoplasms 29085504 "Curcumin inhibits cell proliferation and promotes apoptosis of laryngeal cancer cells through Bcl-2 and PI3K/Akt, and by upregulating miR-15a." other hsa-mir-29b Brain Disease [unspecific] 29087603 MiR-29b expression is associated with a dexmedetomidine-mediated protective effect against oxygen-glucose deprivation-induced injury to SK-N-SH cells in vitro. other hsa-mir-138 "Squamous Cell Carcinoma, Oral" 29088820 "Knockdown of fascin in OSCC cells promoted cell adhesion and inhibited migration, invasion and EMT, and forced expression of miR-138 in OSCC cells significantly decreased the expression of fascin" other hsa-mir-21 Liver Neoplasms 29091291 Genetic and pharmacologic manipulation of miR-21 does not inhibit the development of liver fibrosis and liver cancer other hsa-mir-1 Myocardial Infarction 29094045 Effect of Wenxin Granules on Gap Junction and MiR-1 in Rats with Myocardial Infarction. other hsa-mir-140 Osteoarthritis 29095952 Computer simulation models as a tool to investigate the role of microRNAs in osteoarthritis. other hsa-mir-222 Gastric Neoplasms 29098549 The GAS5/miR-222 Axis Regulates Proliferation of Gastric Cancer Cells Through the PTEN/Akt/mTOR Pathway. other hsa-mir-24 Breast Neoplasms 29103019 Propofol induces apoptosis of breast cancer cells by downregulation of miR-24 signal pathway. other hsa-mir-155 Allergic Asthma 29104649 Small interfering RNA directed against microRNA-155 delivered by a lentiviral vector attenuates asthmatic features in a mouse model of allergic asthma. other hsa-mir-34a "Carcinoma, Renal Cell" 29104726 MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma. other hsa-mir-676 Hypohidrotic Ectodermal Dysplasia 29106399 A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle. other hsa-mir-132 Salivary Gland Neoplasms 29108921 "miR-17, miR-132, miR-195 and miR-221 seem to play an important role as tumor suppressor in salivary gland tumors" other hsa-mir-17 Salivary Gland Neoplasms 29108921 "miR-17, miR-132, miR-195 and miR-221 seem to play an important role as tumor suppressor in salivary gland tumors" other hsa-mir-195 Salivary Gland Neoplasms 29108921 "miR-17, miR-132, miR-195 and miR-221 seem to play an important role as tumor suppressor in salivary gland tumors" other hsa-mir-221 Salivary Gland Neoplasms 29108921 "miR-17, miR-132, miR-195 and miR-221 seem to play an important role as tumor suppressor in salivary gland tumors" other hsa-mir-210 Stroke 29111308 Inhibition of microRNA-210 suppresses pro-inflammatory response and reduces acute brain injury of ischemic stroke in mice. other hsa-mir-10a Breast Neoplasms 29113237 MicroRNA-10a suppresses breast cancer progression via PI3K/Akt/mTOR pathway. other hsa-mir-1 Heart Failure 29117535 Rescuing infusion of miRNA-1 prevents cardiac remodeling in a heart-selective miRNA deficient mouse. other hsa-mir-17 Allergy 29122948 MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation. other hsa-mir-34a "Carcinoma, Hepatocellular" 29128099 Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury. other hsa-mir-214 Gastric Neoplasms 29129783 Hypoxia-induced miR-214 expression promotes tumour cell proliferation and migration by enhancing the Warburg effect in gastric carcinoma cells. other hsa-mir-16 "Carcinoma, Hepatocellular" 29136911 "microRNA-155 expression, essential in NK cell activation, was elevated in Foxo3-/- NK cells while its inhibition led to diminished IFN¦Ã production" other hsa-mir-145 "Adenocarcinoma, Pancreatic Ductal" 29137251 Exportin 1 (XPO1) inhibition leads to restoration of tumor suppressor miR-145 and consequent suppression of pancreatic cancer cell proliferation and migration. other hsa-mir-146a Status Epilepticus 29144992 Intracerebroventricular injection of miR-146a relieves seizures in an immature rat model of lithium-pilocarpine induced status epilepticus. other hsa-mir-223 Hepatitis [unspecific] 29145157 BMSCs-derived miR-223-containing exosomes contribute to liver protection in experimental autoimmune hepatitis other hsa-mir-21 Salivary Gland Disease 29154818 MicroRNA-21 promotes wound healing via the Smad7-Smad2/3-Elastin pathway. other hsa-mir-221 Leukemia 29156756 "Increasing knowledge of biological changes, due to altered miRNA dynamics, is expected to have relevant translational implications for leukemia detection and treatment" other hsa-mir-20a "Lymphoma, Large B-Cell, Diffuse" 29156774 MicroRNAs as predictors for CNS relapse of systemic diffuse large B-cell lymphoma other hsa-mir-21 Multiple Myeloma 29158801 Gambogenic Acid Exerts Antitumor Activity in Hypoxic Multiple Myeloma Cells by Regulation of miR-21 other hsa-mir-503 Bladder Neoplasms 29169421 miR-503-5p inhibits the proliferation of T24 and EJ bladder cancer cells by interfering with the Rb/E2F signaling pathway other hsa-let-7b Alzheimer Disease 29170128 let-7b has an important association with the pathology of AD and can be used as an adjunct to improve the diagnostic performance of traditional AD biomarkers other hsa-mir-21 Ischemia-Reperfusion Injury 29170412 Ischemic Postconditioning Protects Against Intestinal Ischemia/Reperfusion Injury via the HIF-1¦Á/miR-21 Axis other hsa-mir-146a Human Papilloma Virus Infection 29181576 "HPV16 induces the overexpression of miR-146a in the initial stages of carcinogenesis (hyperplasia and dysplasia), whereas decreases its expression at later stages (CIS)" other hsa-mir-21 Gastric Neoplasms 29185784 miR-21 Inhibitors Modulate Biological Functions of Gastric Cancer Cells via PTEN/PI3K/mTOR Pathway other hsa-mir-21 Ischemia-Reperfusion Injury 29187695 the activation of the Akt pathway regulated by miR-21 participates in the protective effects of H2S against I/R-induced liver injury other hsa-mir-133a Asthma 29191361 "The relative expression of miRNA-133a increased in the low-dose anti-IgE, high-dose anti-IgE, fluticasone+anti-IgE and anti-TNF groups" other hsa-mir-106b Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-126 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-128 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-132 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-150 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-155 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-15a Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-16 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-17 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-18 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-19a Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-19b Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-19b-1 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-20a Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-27 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-29b Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-31 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-320a Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-326 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-340 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-363 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-550 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-92-1 Multiple Sclerosis 29194612 "our data revealed that the expression of a number of microRNAs including miR-16, miR-17-92, miR-27, miR-29b, miR-126, miR-128, miR-132, miR-155, miR-326, miR-550, miR-15a, miR-19b, miR-106b, miR-320a, miR-363, miR-31, miR-150, and miR-340 is regulated by nanocurcumin" other hsa-mir-204 Hypertension 29196166 "1,25(OH)2D3 was a promising therapeutic modality for treatment of PAH, function of which was exerted through miR-204 mediated Tgfbr2 signaling" other hsa-mir-1273g Diabetic Retinopathy 29197896 miRNA-1273g-3p Involvement in Development of Diabetic Retinopathy by Modulating the Autophagy-Lysosome Pathway. other hsa-mir-126 Atherosclerosis 29203244 MicroRNA-126 alleviates endothelial cells injury in atherosclerosis by restoring autophagic flux via inhibiting of PI3K/Akt/mTOR pathway other hsa-mir-15b Alzheimer Disease 29207665 miR-15b play an important role in the cellular AD phenotype and might be involved in the pathogenesis of AD other hsa-mir-211 Cone Dystrophy 29209045 MiR-211 is essential for adult cone photoreceptor maintenance and visual function. other hsa-mir-1 Myocardial Infarction 29212255 "Soluble epoxide hydrolase inhibitors, t-AUCB, regulated microRNA-1 and its target genes in myocardial infarction mice" other hsa-mir-155 Breast Neoplasms 29214365 "Profiling differential microRNA expression between in situ, infiltrative and lympho-vascular space invasive breast cancer: a pilot study" other hsa-mir-10a Alzheimer Disease 29215712 miR-10a restrains synapse remodeling and neuronal cell proliferation while promoting apoptosis in AD rats via inhibiting BDNF-TrkB signaling pathway other hsa-mir-193a Prostate Neoplasms 29216925 Silencing of miR-193a-5p increases the chemosensitivity of prostate cancer cells to docetaxel. other hsa-mir-29a Neoplasms [unspecific] 29217524 "we discussed the functions of miR-29a and its potential application in the diagnosis, treatment and stages of carcinoma, which could provide additional insight to develop a novel therapeutic strategy" other hsa-mir-124 Stroke 29221142 D-4F increases microRNA-124a and reduces neuroinflammation in diabetic stroke rats other hsa-mir-130a Colon Neoplasms 29225578 Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/¦Â-Catenin Pathways via miR-130a other hsa-mir-34a Breast Neoplasms 29226432 the intracellular function of miR-34a delivered by the nanocomplex to upregulate active Caspase-3 was imaged in real-time other hsa-mir-155 Lymphoma 29228427 MiR-155 regulates lymphoma cell proliferation and apoptosis through targeting SOCS3/JAK-STAT3 signaling pathway other hsa-mir-204 Prostate Neoplasms 29228612 MiR-204 enhances mitochondrial apoptosis in doxorubicin-treated prostate cancer cells by targeting SIRT1/p53 pathway other hsa-mir-21 Liver Injury 29229992 miRNA-21 ablation protects against liver injury and necroptosis in cholestasis other hsa-mir-128 Asthma 29231896 Downregulated miR-128 and miR-744 supports a Th2/Th17 type immune response in severe equine asthma other hsa-mir-744 Asthma 29231896 Downregulated miR-128 and miR-744 supports a Th2/Th17 type immune response in severe equine asthma other hsa-mir-126 Ischemia 29242072 Therapeutic angiogenesis by local sustained release of microRNA-126 using poly lactic-co-glycolic acid nanoparticles in murine hindlimb ischemia other hsa-mir-27b Endometriosis 29247225 "Rg3 effectively altered fibrotic properties of HESCs from patients with endometriosis, which is likely associated with miR-27b-3p modulation" other hsa-mir-124 "Carcinoma, Pancreatic" 29255366 circRNA_100782 regulates BxPC3 cell proliferation by acting as miR-124 sponge through the IL6-STAT3 pathway other hsa-mir-30a "Squamous Cell Carcinoma, Esophageal" 29259372 Down-regulation of miR-30a-3p/5p promotes esophageal squamous cell carcinoma cell proliferation by activating the Wnt signaling pathway other hsa-mir-144 Melanoma 29260980 Baohuoside-I suppresses cell proliferation and migration by up-regulating miR-144 in melanoma other hsa-mir-155 Crohn Disease 29263823 a small subset had inflammatory responses almost comparable to wild-type patients on both gene and miR-155 regulatory levels other hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 29266356 Effect of microRNA-145 on proliferation and apoptosis of human non-small cell lung cancer A549 cells by regulating mTOR signaling pathway other hsa-mir-320 IgA Nephropathy 29266359 MiR-320 promotes B cell proliferation and the production of aberrant glycosylated IgA1 in IgA nephropathy. other hsa-mir-146a "Squamous Cell Carcinoma, Oral" 29269299 the activation of TLR2 by bacterial components can enhance the progression of OSCC and may be implicated in acquired resistance to cisplatin-induced apoptosis through regulation of the miR-146a pathway other hsa-mir-144 Anemia 29269522 miR-144/451 represses the LKB1/AMPK/mTOR pathway to promote red cell precursor survival during recovery from acute anemia other hsa-mir-221 Prostate Neoplasms 29281088 "Combining radiation dose parameters with microRNA expression in PBLs may be useful for predicting acute gastrointestinal toxicity of radiation therapy, thus contributing to personalized treatment of prostate cancer" other hsa-mir-21 Allergic Contact Dermatitis 29282578 "MicroRNA-21-Mediated Inhibition of Mast Cell Degranulation Involved in the Protective Effect of Berberine on 2,4-Dinitrofluorobenzene-Induced Allergic Contact Dermatitis in Rats via p38 Pathway" other hsa-mir-503 Diabetes Mellitus 29285014 microRNA-503 contribute to pancreatic beta cell dysfunction by targeting the mTOR pathway in gestational diabetes mellitus other hsa-mir-106b Cholangiocarcinoma 29286255 miR-106b-responsive gene landscape identifies regulation of Kruppel-like factor family other hsa-mir-214 "Adenocarcinoma, Lung" 29288987 Machine Learning Based Prediction of Brain Metastasis of Patients with IIIA-N2 Lung Adenocarcinoma by a Three-miRNA Signature other hsa-mir-146a Osteoarthritis 29292727 the modification of miR-146a and miR-34a in OA chondrocytes subjected to H2O2 stimulus and we confirmed the antioxidant effect of taurine other hsa-mir-34a Osteoarthritis 29292727 the modification of miR-146a and miR-34a in OA chondrocytes subjected to H2O2 stimulus and we confirmed the antioxidant effect of taurine other hsa-mir-34a Pancreatic Neoplasms 29295989 Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer other hsa-mir-21 Neurilemmoma 29298734 Ailanthone promotes human vestibular schwannoma cells apoptosis and autophagy by down-regulation of miR-21 other hsa-mir-16 Coronary Artery Disease 29306454 "HDLs are depleted of miR-16, miR-92a and miR-223 during the transcoronary passage in patients with ACS compared to patients with stable CAD" other hsa-mir-223 Coronary Artery Disease 29306454 "HDLs are depleted of miR-16, miR-92a and miR-223 during the transcoronary passage in patients with ACS compared to patients with stable CAD" other hsa-mir-92a Coronary Artery Disease 29306454 "HDLs are depleted of miR-16, miR-92a and miR-223 during the transcoronary passage in patients with ACS compared to patients with stable CAD" other hsa-mir-21 Multiple Myeloma 29320977 Ibrutinib targets microRNA-21 in multiple myeloma cells by inhibiting NF-¦ÊB and STAT3 other hsa-mir-212 Prostate Neoplasms 29321092 MicroRNA-212 Targets Mitogen-Activated Protein Kinase 1 to Inhibit Proliferation and Invasion of Prostate Cancer Cells. other hsa-mir-130a Hepatitis C Virus Infection 29321333 MicroRNA 130a Regulates both Hepatitis C Virus and Hepatitis B Virus Replication through a Central Metabolic Pathway. other hsa-mir-15a Mitochondrial Metabolism Disease 29322081 Data of expression status of miR-29a and its putative target mitochondrial apoptosis regulatory gene DRP1 upon miR-15a and miR-214 inhibition other hsa-mir-214 Mitochondrial Metabolism Disease 29322081 Data of expression status of miR-29a and its putative target mitochondrial apoptosis regulatory gene DRP1 upon miR-15a and miR-214 inhibition other hsa-mir-221 "Carcinoma, Hepatocellular" 29322790 miR-221 and miR-222 might affect the pathogenesis of HCC other hsa-mir-222 "Carcinoma, Hepatocellular" 29322790 miR-221 and miR-223 might affect the pathogenesis of HCC other hsa-mir-1 Myocardial Infarction 29324314 "up-regulation of miR-1 and miR-208 in remote myocardium might play a role in cardiac remodeling after MI, at least to certain degree" other hsa-mir-208 Myocardial Infarction 29324314 "up-regulation of miR-1 and miR-208 in remote myocardium might play a role in cardiac remodeling after MI, at least to certain degree" other hsa-mir-181b "Adenocarcinoma, Lung" 29324442 ZEB1 initiates a miR-181b-regulated ceRNA network to drive metastasis other hsa-mir-184 Age-Related Macular Degeneration 29325388 "miR-184 plays crucial regulatory roles in several ocular diseases, such as neovascularization, keratoconus, endothelial dystrophy, iris hypoplasia, congenital cataract, stromal thinning syndrome, corneal squamous cell carcinoma, age-related macular degeneration and cataract" other hsa-mir-184 Cataract 29325388 "miR-184 plays crucial regulatory roles in several ocular diseases, such as neovascularization, keratoconus, endothelial dystrophy, iris hypoplasia, congenital cataract, stromal thinning syndrome, corneal squamous cell carcinoma, age-related macular degeneration and cataract" other hsa-mir-184 Cornea Squamous Cell Carcinoma 29325388 "miR-184 plays crucial regulatory roles in several ocular diseases, such as neovascularization, keratoconus, endothelial dystrophy, iris hypoplasia, congenital cataract, stromal thinning syndrome, corneal squamous cell carcinoma, age-related macular degeneration and cataract" other hsa-mir-122 Chronic Hepatitis C 29327233 DCAF1 is involved in HCV replication through regulation of miR-122 and thus provides new insights into the interaction between HCV and the host cell other hsa-mir-203 "Carcinoma, Endometrial" 29331043 Role of miR-203 in estrogen receptor-mediated signaling in the rat uterus and endometrial carcinoma other hsa-mir-146a Multiple Myeloma 29333170 Multiple Myeloma-Derived Exosomes Regulate the Functions of Mesenchymal Stem Cells Partially via Modulating miR-21 and miR-146a other hsa-mir-21 Multiple Myeloma 29333170 Multiple Myeloma-Derived Exosomes Regulate the Functions of Mesenchymal Stem Cells Partially via Modulating miR-21 and miR-146a other hsa-mir-466 Colorectal Carcinoma 29338680 MicroRNA-466 (miR-466) functions as a tumor suppressor and prognostic factor in colorectal cancer (CRC). other hsa-mir-122 Chronic Hepatitis C 29343570 the 5'-proximal EHcV-specific region enhances viral replication and RNA stability in a miR-122-independent manner other hsa-mir-16 "Carcinoma, Hepatocellular" 29344256 Pien Tze Huang inhibits the growth of hepatocellular carcinoma cells by upregulating miR-16 expression other hsa-mir-155 Hepatitis B Virus Infection 29349567 HBeAg induces the expression of macrophage miR-155 to accelerate liver injury via promoting production of inflammatory cytokines. other hsa-mir-17 Glioma 29351283 "The reduced miR-17 levels in glioma cells increased cell viability and migration, which correlates with increased expression of Cyclin D1, p-Akt and Akt" other hsa-mir-125b Inflammation 29354323 "Up-Regulation of the Pro-Inflammatory Cytokines IL-6 and TNF¦Á, C-Reactive Protein (CRP) and miRNA-146a in Blood Serum" other hsa-mir-146b Sciatic Nerve Injury 29356943 Inhibition of KLF7-Targeting MicroRNA 146b Promotes Sciatic Nerve Regeneration. other hsa-mir-193a Wilms Tumor 29357419 Modulation of apolipoprotein L1-microRNA-193a axis prevents podocyte dedifferentiation in high-glucose milieu. other hsa-mir-143 Colon Neoplasms 29360852 miR-143 might circumvent resistance of colon cancer cells to oxaliplatin via increased oxidative stress in HCT116 human colon cancer cells other hsa-mir-145 "Carcinoma, Colon" 29360852 We show that approximately 100 proteins are differentially expressed in HCT116 human colon cancer cells stably transduced with miR-143 or miR-145 compared to Empty control cells other hsa-mir-18a Hypoxia 29363860 ACE-EPCs-EXs have better protective effects on H/R injury in ageing ECs which could be through their carried miR-18a and subsequently down-regulating the Nox2/ROS pathway other hsa-mir-31 Prostate Neoplasms 29364469 Estramustine phosphate induces prostate cancer cell line PC3 apoptosis by down-regulating miR-31 levels other hsa-mir-155 Neoplasms [unspecific] 29366836 Increased miR-155 expression was associated with poorer survival in human carcinoma and as such may be valuable in predicting outcome other hsa-mir-31 "Adenocarcinoma, Lung" 29367106 down-regulation of MIR31HG had no effect on the expression of miR-31 in lung adenocarcinoma cells other hsa-mir-221 Alveolar Rhabdomyosarcoma 29367756 PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma. other hsa-mir-486 Alveolar Rhabdomyosarcoma 29367756 PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma. other hsa-mir-372 Neoplasms [unspecific] 29374231 Modulation of oncogenic miRNA biogenesis using functionalized polyamines other hsa-mir-31 Medulloblastoma 29377269 Ginsenoside Rh2 inhibits proliferation and migration of medulloblastoma Daoy by down-regulation of microRNA-31 other hsa-mir-124 Pediatric Ependymoma 29383182 "The tumor suppressor, hsa-miR-124, was down regulated in pediatric SEPN and it normally represses genes involved in cell-cell communication and metabolic processes" other hsa-mir-17 Bladder Neoplasms 29386015 "Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression" other hsa-mir-224 Bladder Neoplasms 29386015 "Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression" other hsa-mir-224 "Carcinoma, Lung, Non-Small-Cell" 29387235 "Predictive relevance of miR-34a, miR-224 and miR-342 in patients with advanced squamous cell carcinoma of the lung undergoing palliative chemotherapy" other hsa-mir-342 "Carcinoma, Lung, Non-Small-Cell" 29387235 "Predictive relevance of miR-34a, miR-224 and miR-342 in patients with advanced squamous cell carcinoma of the lung undergoing palliative chemotherapy" other hsa-mir-34a "Carcinoma, Lung, Non-Small-Cell" 29387235 "Predictive relevance of miR-34a, miR-224 and miR-342 in patients with advanced squamous cell carcinoma of the lung undergoing palliative chemotherapy" other hsa-mir-23a Neoplasms [unspecific] 29387410 the miR-23a/24-2/27a cluster may be a useful marker for predicting cancer prognosis and tumor progression other hsa-mir-24-2 Neoplasms [unspecific] 29387410 the miR-23a/24-2/27a cluster may be a useful marker for predicting cancer prognosis and tumor progression other hsa-mir-27a Neoplasms [unspecific] 29387410 the miR-23a/24-2/27a cluster may be a useful marker for predicting cancer prognosis and tumor progression other hsa-mir-34a Liver Diseases [unspecific] 29391755 "After normalization of the steatosis-related circRNA by expression vector, analysis of miR-34a activity, peroxisome proliferator-activated receptor (PPAR)¦Á level, and expression of downstream genes were carried out so as to reveal its impact on the miR-34a/PPAR¦Á regulatory system" other hsa-mir-27a Breast Neoplasms 29393459 Liraglutide inhibits the proliferation and promotes the apoptosis of MCF-7 human breast cancer cells through downregulation of microRNA-27a expression other hsa-mir-17 Hypoxic-Ischemic Encephalopathy 29394934 IRE1¦Á inhibition decreased TXNIP/NLRP3 inflammasome activation through miR-17-5p after neonatal hypoxic-ischemic brain injury in rats other hsa-mir-17 Infertility 29402772 Ablation of the MiR-17-92 MicroRNA Cluster in Germ Cells Causes Subfertility in Female Mice other hsa-mir-18 Infertility 29402772 Ablation of the MiR-17-92 MicroRNA Cluster in Germ Cells Causes Subfertility in Female Mice other hsa-mir-19a Infertility 29402772 Ablation of the MiR-17-92 MicroRNA Cluster in Germ Cells Causes Subfertility in Female Mice other hsa-mir-19b-1 Infertility 29402772 Ablation of the MiR-17-92 MicroRNA Cluster in Germ Cells Causes Subfertility in Female Mice other hsa-mir-20a Infertility 29402772 Ablation of the MiR-17-92 MicroRNA Cluster in Germ Cells Causes Subfertility in Female Mice other hsa-mir-92-1 Infertility 29402772 Ablation of the MiR-17-92 MicroRNA Cluster in Germ Cells Causes Subfertility in Female Mice other hsa-mir-592 Ischemia 29402808 Effects of MicroRNA-592-5p on Hippocampal Neuron Injury Following Hypoxic-Ischemic Brain Damage in Neonatal Mice - Involvement of PGD2/DP and PTGDR. other hsa-mir-16 Vascular Disease [unspecific] 29402872 "This revascularization is associated with a decrease in miRNA-16 expression permissive for increased VEGF protein expression, suggesting a mechanism for potential therapeutic application in vascular diseases" other hsa-mir-370 Ovarian Neoplasms 29403287 Long noncoding RNA H19 promotes transforming growth factor-¦Â-induced epithelial-mesenchymal transition by acting as a competing endogenous RNA of miR-370-3p in ovarian cancer cells other hsa-mir-145 Colorectal Carcinoma 29404790 the pattern of miRNA expression and its correlation with histological markers are potentially valuable to apply as diagnostic biomarkers for CRC other hsa-mir-20a Colorectal Carcinoma 29404790 the pattern of miRNA expression and its correlation with histological markers are potentially valuable to apply as diagnostic biomarkers for CRC other hsa-mir-21 Colorectal Carcinoma 29404790 the pattern of miRNA expression and its correlation with histological markers are potentially valuable to apply as diagnostic biomarkers for CRC other hsa-mir-155 Allergic Contact Dermatitis 29404871 Involvement of the Negative Feedback of IL-33 Signaling in the Anti-Inflammatory Effect of Electro-acupuncture on Allergic Contact Dermatitis via Targeting MicroRNA-155 in Mast Cells other hsa-let-7 Brain Disease [unspecific] 29408500 MicroRNA let-7c-5p improves neurological outcomes in a murine model of traumatic brain injury by suppressing neuroinflammation and regulating microglial activation other hsa-mir-122 Hepatitis C Virus Infection 29411512 This result along with the idea about the driver function of circulating miRNAs will promote further investigations that eventually lead to the development of novel strategies to treat HCV infection-associated extrahepatic comorbidities other hsa-mir-7 Ovarian Neoplasms 29411964 Enhanced Chemotherapeutic Efficacy of Paclitaxel Nanoparticles Co-delivered with MicroRNA-7 by Inhibiting Paclitaxel-Induced EGFR/ERK pathway Activation for Ovarian Cancer Therapy other hsa-mir-21 Gastric Neoplasms 29422082 CBX7 regulates stem cell-like properties of gastric cancer cells via p16 and AKT-NF-¦ÊB-miR-21 pathways other hsa-mir-181a Neuroblastoma 29426375 Triptolide inhibits proliferation and migration of human neuroblastoma SH-SY5Y cells by up-regulating microRNA-181a other hsa-mir-409 Sarcoma [unspecific] 29430619 "A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons." other hsa-mir-495 Sarcoma [unspecific] 29430619 "A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons." other hsa-mir-449a Breast Neoplasms 29431182 Comprehensive circular RNA profiling reveals the regulatory role of the circRNA-000911/miR-449a pathway in breast carcinogenesis other hsa-mir-181b "Adenocarcinoma, Lung" 29434967 Celastrol suppresses the proliferation of lung adenocarcinoma cells by regulating microRNA-24 and microRNA-181b other hsa-mir-24 "Adenocarcinoma, Lung" 29434967 Celastrol suppresses the proliferation of lung adenocarcinoma cells by regulating microRNA-24 and microRNA-181b other hsa-mir-146a Atrial Fibrillation 29437577 MiR-146a Regulates Neutrophil Extracellular Trap Formation That Predicts Adverse Cardiovascular Events in Patients With Atrial Fibrillation other hsa-mir-21 Ischemic Heart Disease 29444190 Bone marrow mesenchymal stem cell-derived exosomal miR-21 protects C-kit+ cardiac stem cells from oxidative injury through the PTEN/PI3K/Akt axis other hsa-mir-223 Inflammation 29444433 MicroRNA-223 Suppresses the Canonical NF-¦ÊB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation other hsa-mir-146a Atherosclerosis 29449647 "they express a remarkably high basal level of miR-146a, a microRNA known to negatively regulate the TLR pathway" other hsa-mir-146a Osteoarthritis 29449647 "they express a remarkably high basal level of miR-147a, a microRNA known to negatively regulate the TLR pathway" other hsa-mir-630 Ovarian Neoplasms 29452092 MicroRNA-630 inhibitor sensitizes chemoresistant ovarian cancer to chemotherapy by enhancing apoptosis. other hsa-let-7f Asthma 29455573 A CREB-mediated increase in miRNA let-7f during prolonged ¦Â-agonist exposure: a novel mechanism of ¦Â2-adrenergic receptor down-regulation in airway smooth muscle other hsa-mir-214 Gastric Neoplasms 29456019 Exosomes Serve as Nanoparticles to Deliver Anti-miR-214 to Reverse Chemoresistance to Cisplatin in Gastric Cancer other hsa-mir-21 Cardiovascular Diseases [unspecific] 29456377 the stability of both DIM and pre-miR-21 was found to be inversely correlated to each other in binding condition other hsa-mir-21 Vascular Disease [unspecific] 29456377 the stability of both DIM and pre-miR-22 was found to be inversely correlated to each other in binding condition other hsa-mir-21 Colorectal Carcinoma 29456985 Evaluation of miR-21 Inhibition and its Impact on Cancer Susceptibility Candidate 2 Long Noncoding RNA in Colorectal Cancer Cell Line other hsa-mir-145 Gastrointestinal Neoplasms 29459716 "miR-145, which blocked EGFR endocytosis, prolonged EGFR membrane signaling and altered responsiveness of colon cancer cells to EGFR-targeting drugs" other hsa-mir-17 Gastrointestinal Neoplasms 29459716 "The regulation of EGF receptor (EGFR) endocytosis by two predicted miRNAs, namely miR-17 and miR-145, was confirmed experimentally" other hsa-mir-125b Spinal Cord Injuries 29461585 MicroRNA-125b promotes the regeneration and repair of spinal cord injury through regulation of JAK/STAT pathway other hsa-mir-143 Endometriosis 29463003 "miR-17-5p/20a, miR-200, miR-199a, miR-143, and miR-145 were explored for their pivotal role in the aetiopathogenesis of endometriosis" other hsa-mir-145 Endometriosis 29463003 "miR-17-5p/20a, miR-200, miR-199a, miR-143, and miR-145 were explored for their pivotal role in the aetiopathogenesis of endometriosis" other hsa-mir-17 Endometriosis 29463003 "miR-17-5p/20a, miR-200, miR-199a, miR-143, and miR-145 were explored for their pivotal role in the aetiopathogenesis of endometriosis" other hsa-mir-199a Endometriosis 29463003 "miR-17-5p/20a, miR-200, miR-199a, miR-143, and miR-145 were explored for their pivotal role in the aetiopathogenesis of endometriosis" other hsa-mir-200 Endometriosis 29463003 "miR-17-5p/20a, miR-200, miR-199a, miR-143, and miR-145 were explored for their pivotal role in the aetiopathogenesis of endometriosis" other hsa-mir-20a Endometriosis 29463003 "miR-17-5p/20a, miR-200, miR-199a, miR-143, and miR-145 were explored for their pivotal role in the aetiopathogenesis of endometriosis" other hsa-mir-145 Pancreatic Neoplasms 29464032 Selective packaging of miRNAs into EVs led to enrichment of stromal specific miR-145 in EVs secreted by TAS cells other hsa-mir-155 Atherosclerosis 29465752 both the atherosclerosis inducer ox-LDL and atheroprotective factor KLF2 regulated inflammation-associated microRNA-155 (miR-155) expression in human umbilical vein endothelial cells (HUVECs) other hsa-mir-675 Neuroblastoma 29465760 "Angelica sinensis polysaccharide inhibits proliferation, migration, and invasion by downregulating microRNA-675 in human neuroblastoma cell line SH-SY5Y." other hsa-mir-132 Infection [unspecific] 29467760 MicroRNA Regulation of Host Immune Responses following Fungal Exposure other hsa-mir-146a Infection [unspecific] 29467760 MicroRNA Regulation of Host Immune Responses following Fungal Exposure other hsa-mir-126 Status Epilepticus 29468563 the analysis of miRNA levels in serum could provide clinicians with a tool to evaluate disease evolution and the efficacy of ¦Á-T therapy in SE other hsa-mir-590 Gastric Neoplasms 29473240 Loss of PPM1F expression predicts tumour recurrence and is negatively regulated by miR-590-3p in gastric cancer. other hsa-mir-371a Germ Cell Tumor 29474847 Serum miRNA Predicts Viable Disease after Chemotherapy in Patients with Testicular Nonseminoma Germ Cell Tumor. other hsa-mir-182 Sensorineural Hearing Loss 29476110 "A mouse model of miR-96, miR-182 and miR-183 misexpression implicates miRNAs in cochlear cell fate and homeostasis" other hsa-mir-183 Sensorineural Hearing Loss 29476110 "A mouse model of miR-96, miR-182 and miR-183 misexpression implicates miRNAs in cochlear cell fate and homeostasis" other hsa-mir-96 Sensorineural Hearing Loss 29476110 "A mouse model of miR-96, miR-182 and miR-183 misexpression implicates miRNAs in cochlear cell fate and homeostasis" other hsa-mir-126 Diabetes Mellitus 29477147 "While both miRs have differential functions on endothelial VCAM expression, miR-19a and miR-126 cooperate to exhibit anti-thrombotic properties via regulating vascular TF expression" other hsa-mir-19a Diabetes Mellitus 29477147 "While both miRs have differential functions on endothelial VCAM expression, miR-19a and miR-126 cooperate to exhibit anti-thrombotic properties via regulating vascular TF expression" other hsa-mir-30c Cardiovascular Diseases [unspecific] 29483230 Cocaine Exposure Increases Blood Pressure and Aortic Stiffness via the miR-30c-5p-Malic Enzyme 1-Reactive Oxygen Species Pathway. other hsa-mir-210 Myocardial Infarction 29484401 MicroRNA-210 promotes angiogenesis in acute myocardial infarction other hsa-mir-16 Acute Lung Injury 29484411 miR-16 inhibits hyperoxia-induced cell apoptosis in human alveolar epithelial cells other hsa-mir-146a Non-Syndromic Orofacial Clefts 29484780 A functional polymorphism in the pre-miR-146a gene is associated with the risk of nonsyndromic orofacial cleft. other hsa-mir-206 Amyotrophic Lateral Sclerosis 29486297 Muscle microRNA signatures as biomarkers of disease progression in amyotrophic lateral sclerosis. other hsa-mir-31 "Adenocarcinoma, Pancreatic Ductal" 29486633 The AT-rich interactive domain 1A expression level in the cells was increased following microRNA-31 (miR-31) inhibitor transfection other hsa-mir-122 Chronic Hepatitis C 29486652 Functional sequestration of microRNA-122 from Hepatitis C Virus by circular RNA sponges other hsa-mir-133b Diabetic Retinopathy 29488353 Effects of microRNA-133b on retinal vascular endothelial cell proliferation and apoptosis through angiotensinogen-mediated angiotensin II- extracellular signal-regulated kinase 1/2 signalling pathway in rats with diabetic retinopathy. other hsa-mir-9 "Adenocarcinoma, Lung" 29492899 differences in cell response (both miR-9 and proliferation) to dexamethasone in na?ve and desialylated cells may point to non-genomic dexamethasone effects other hsa-mir-20a Colon Neoplasms 29492958 Targeting liver sinusoidal endothelial cells with miR-20a-loaded nanoparticles reduces murine colon cancer metastasis to the liver. other hsa-mir-124 Stroke 29494665 MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo other hsa-mir-9 Human Immunodeficiency Virus Infection 29497921 Exosomal miR-9 Released from HIV Tat Stimulated Astrocytes Mediates Microglial Migration other hsa-mir-21 Lung Neoplasms 29501572 "Involvement of HIF-1¦Á-regulated miR-21, acting via the Akt/NF-¦ÊB pathway, in malignant transformation of HBE cells induced by cigarette smoke extract." other hsa-mir-21 Atherosclerosis 29503197 Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions other hsa-mir-144 "Carcinoma, Thyroid, Anaplastic" 29504819 Effects of miR-144 on the sensitivity of human anaplastic thyroid carcinoma cells to cisplatin by autophagy regulation. other hsa-mir-126 "Leukemia, Myelogenous, Chronic, BCR-ABL Positive" 29505034 Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia other hsa-mir-1 Myocardial Ischemic-Reperfusion Injury 29505745 Cardioprotective effect of paeonol against epirubicin-induced heart injury via regulating miR-1 and PI3K/AKT pathway other hsa-mir-137 "Diabetes Mellitus, Gestational" 29505767 High glucose induces dysfunction of human umbilical vein endothelial cells by upregulating miR-137 in gestational diabetes mellitus. other hsa-mir-208b Hypertension 29506053 "miR-26b, miR-208b and miR-499 show a distinct in profile in hypertensive patients with HFpEF that is related with functional capacity" other hsa-mir-26b Hypertension 29506053 "miR-26b, miR-208b and miR-499 show a distinct in profile in hypertensive patients with HFpEF that is related with functional capacity" other hsa-mir-499 Hypertension 29506053 "miR-26b, miR-208b and miR-499 show a distinct in profile in hypertensive patients with HFpEF that is related with functional capacity" other hsa-mir-208a Myocardial Infarction 29506703 Droplet digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction other hsa-mir-21 Arteriosclerosis Obliterans 29506703 Droplet digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction other hsa-mir-21 Ischemia-Reperfusion Injury 29506703 Droplet digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction other hsa-mir-21 Myocardial Infarction 29506703 Droplet digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction other hsa-mir-499 Myocardial Infarction 29506703 Droplet digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction other hsa-mir-384 Diabetic Encephalopathy 29511445 Control of macrophage autophagy by miR-384-5p in the development of diabetic encephalopathy. other hsa-mir-191 "Carcinoma, Breast" 29511965 levels of miR-191-5p significantly increased during the six-month intervention other hsa-mir-21 Colorectal Adenocarcinoma 29512659 An amplification-free electrochemical detection of exosomal miRNA-21 in serum samples other hsa-mir-155 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 29517281 YB-1 promotes laryngeal squamous cell carcinoma progression by inducing miR-155 expression via c-Myb. other hsa-mir-196a "Carcinoma, Hepatocellular" 29518473 Gene expression network regulated by DNA methylation and microRNA during microcystin-leucine arginine induced malignant transformation in human hepatocyte L02 cells. other hsa-mir-221 "Carcinoma, Hepatocellular" 29518473 Gene expression network regulated by DNA methylation and microRNA during microcystin-leucine arginine induced malignant transformation in human hepatocyte L02 cells. other hsa-mir-26a "Carcinoma, Hepatocellular" 29518473 Gene expression network regulated by DNA methylation and microRNA during microcystin-leucine arginine induced malignant transformation in human hepatocyte L02 cells. other hsa-mir-320a "Carcinoma, Hepatocellular" 29518473 Gene expression network regulated by DNA methylation and microRNA during microcystin-leucine arginine induced malignant transformation in human hepatocyte L02 cells. other hsa-mir-331 "Carcinoma, Hepatocellular" 29518473 Gene expression network regulated by DNA methylation and microRNA during microcystin-leucine arginine induced malignant transformation in human hepatocyte L02 cells. other hsa-mir-145 Glioblastoma 29521593 Inhibition of glioblastoma cell invasion by hsa-miR-145-5p and hsa-miR-31-5p co-overexpression in human mesenchymal stem cells other hsa-mir-31 Glioblastoma 29521593 Inhibition of glioblastoma cell invasion by hsa-miR-145-5p and hsa-miR-31-6p co-overexpression in human mesenchymal stem cells other hsa-mir-204 Melanoma 29523154 "miR-204 represents a relevant mechanism in melanoma, with potential prognostic value and its loss seems to act in the CDKN2A pathway, in cooperation with NRAS" other hsa-mir-124 Stroke 29524052 "this network-based approach to delineate miRNA, TF, and gene interactions might promote the development of effective therapeutics against ischemic stroke" other hsa-mir-155 Stroke 29527155 the functions of the miRNA miR-155 and the effect of its in vivo inhibition on brain recovery following experimental cerebral ischemia other hsa-mir-122 Hepatitis C Virus Infection 29528577 microRNA-122 is a potential marker of progression of hepatocytes injury in patients infected with HCV but not a reliable marker for diagnosis of HCC other hsa-mir-27a "Adenocarcinoma, Cervical" 29531222 miR-27a inhibits cervical adenocarcinoma progression by downregulating the TGF-¦ÂRI signaling pathway. other hsa-mir-200c Breast Neoplasms 29532351 Bioluminescence Imaging for Monitoring miR-200c Expression in Breast Cancer Cells and its Effects on Epithelial-Mesenchymal Transition Progress in Living Animals other hsa-mir-130a Osteoarthritis 29532889 MicroRNA-130a regulates chondrocyte proliferation and alleviates osteoarthritis through PTEN/PI3K/Akt signaling pathway other hsa-let-7i Diabetic Polyneuropathy 29533535 "let-7i is widely expressed in sensory neurons, supports their growth and is depleted in experimental DPN" other hsa-mir-122 "Carcinoma, Hepatocellular" 29534065 "We identified a miRNA panel comprised of four miRNAs (miR-192, miR-122, miR-181b and miR-125a-5p) that may serve as a molecular tool for characterization of the CD134+ cells associated with different stages of hepatocarinogensis" other hsa-mir-125a "Carcinoma, Hepatocellular" 29534065 "We identified a miRNA panel comprised of four miRNAs (miR-192, miR-122, miR-181b and miR-125a-5p) that may serve as a molecular tool for characterization of the CD136+ cells associated with different stages of hepatocarinogensis" other hsa-mir-181b "Carcinoma, Hepatocellular" 29534065 "We identified a miRNA panel comprised of four miRNAs (miR-192, miR-122, miR-181b and miR-125a-5p) that may serve as a molecular tool for characterization of the CD135+ cells associated with different stages of hepatocarinogensis" other hsa-mir-192 "Carcinoma, Hepatocellular" 29534065 "We identified a miRNA panel comprised of four miRNAs (miR-192, miR-122, miR-181b and miR-125a-5p) that may serve as a molecular tool for characterization of the CD133+ cells associated with different stages of hepatocarinogensis" other hsa-mir-425 Respiratory System Disease 29535266 Prader-Willi region non-protein coding RNA 1 suppressed gastric cancer growth as a competing endogenous RNA of miR-425-5p. other hsa-mir-181a Inflammation 29535629 we provide the first evidence for the negative regulation of miR-181a in LPS-induced inflammation via the suppression of ROS generation and TLR4-NF-¦ÊB pathway other hsa-mir-21 "Carcinoma, Hepatocellular" 29538313 our analysis identified novel miR-21 targets that are likely to play a causal role in hepatocarcinogenesis other hsa-mir-122 Hepatitis E Virus Infection 29540601 Positive regulation of hepatitis E virus replication by microRNA-122 other hsa-mir-21 Chronic Obstructive Pulmonary Disease 29543496 MicroRNA-21 aggravates chronic obstructive pulmonary disease by promoting autophagy other hsa-mir-29b Colon Neoplasms 29545333 A miR-29b Byproduct Sequence Exhibits Potent Tumor-Suppressive Activities via Inhibition of NF-¦ÊB Signaling in KRAS-Mutant Colon Cancer Cells other hsa-mir-106b Brain Neoplasms 29547527 The Oncogenic Relevance of miR-17-92 Cluster and Its Paralogous miR-106b-25 and miR-106a-363 Clusters in Brain Tumors other hsa-mir-17 Brain Neoplasms 29547527 The Oncogenic Relevance of miR-17-92 Cluster and Its Paralogous miR-106b-25 and miR-106a-363 Clusters in Brain Tumors other hsa-mir-18 Brain Neoplasms 29547527 The Oncogenic Relevance of miR-17-92 Cluster and Its Paralogous miR-106b-25 and miR-106a-363 Clusters in Brain Tumors other hsa-mir-19a Brain Neoplasms 29547527 The Oncogenic Relevance of miR-17-92 Cluster and Its Paralogous miR-106b-25 and miR-106a-363 Clusters in Brain Tumors other hsa-mir-19b-1 Brain Neoplasms 29547527 The Oncogenic Relevance of miR-17-92 Cluster and Its Paralogous miR-106b-25 and miR-106a-363 Clusters in Brain Tumors other hsa-mir-20a Brain Neoplasms 29547527 The Oncogenic Relevance of miR-17-92 Cluster and Its Paralogous miR-106b-25 and miR-106a-363 Clusters in Brain Tumors other hsa-mir-25 Brain Neoplasms 29547527 The Oncogenic Relevance of miR-17-92 Cluster and Its Paralogous miR-106b-25 and miR-106a-363 Clusters in Brain Tumors other hsa-mir-92-1 Brain Neoplasms 29547527 The Oncogenic Relevance of miR-17-92 Cluster and Its Paralogous miR-106b-25 and miR-106a-363 Clusters in Brain Tumors other hsa-mir-93 Brain Neoplasms 29547527 The Oncogenic Relevance of miR-17-92 Cluster and Its Paralogous miR-106b-25 and miR-106a-363 Clusters in Brain Tumors other hsa-mir-122 Hepatitis C Virus Infection 29549787 Identification of nucleotides in the 5'UTR and amino acids substitutions that are essential for the infectivity of 5'UTR-NS5A recombinant of hepatitis C virus genotype 1b (strain Con1). other hsa-mir-106b "Squamous Cell Carcinoma, Esophageal" 29552108 miR-106b promotes cell invasion and metastasis via PTEN mediated EMT in ESCC other hsa-mir-375 "Carcinoma, Hepatocellular" 29555460 "miR-375/Sf-LCC NPs can deliver sorafenib and miR-375 into HCC cells and tumor tissues, increase drug retention time in tumor, significantly inhibit autophagy and produce enhanced anti-tumor effect" other hsa-mir-34a Myocardial Infarction 29559958 "miR-34a, a microRNA known to promote pro-apoptotic role in myocardial infarction during degenerative process of cardiac injuries thus indicating intrinsic differences in the nature of the mechanisms underlying the heart failure triggered by Trypanosoma cruzi infection." other hsa-mir-155 Infectious Bursal Disease Virus 29564226 gga-miR-155 plays a critical role in cell response to IBDV infection other hsa-mir-132 "Carcinoma, Breast" 29567542 MicroRNA-132 and microRNA-212 mediate doxorubicin resistance by down-regulating the PTEN-AKT/NF-¦ÊB signaling pathway in breast cancer. other hsa-mir-212 "Carcinoma, Breast" 29567542 MicroRNA-132 and microRNA-212 mediate doxorubicin resistance by down-regulating the PTEN-AKT/NF-¦ÊB signaling pathway in breast cancer. other hsa-let-7a Gastric Neoplasms 29567564 Simultaneous detection of gastric cancer-involved miR-106a and let-7a through a dual-signal-marked electrochemical nanobiosensor. other hsa-mir-106a Gastric Neoplasms 29567564 Simultaneous detection of gastric cancer-involved miR-106a and let-7a through a dual-signal-marked electrochemical nanobiosensor. other hsa-mir-135b Colorectal Carcinoma 29569786 The aggressive function of IL-13/STAT6/ZEB1 axis in colorectal cancer was impaired by propofol through miR-361 and miR-135b other hsa-mir-361 Colorectal Carcinoma 29569786 The aggressive function of IL-13/STAT6/ZEB1 axis in colorectal cancer was impaired by propofol through miR-361 and miR-135b other hsa-mir-192 "Squamous Cell Carcinoma, Lung" 29571988 MiR-192 and miR-662 enhance chemoresistance and invasiveness of squamous cell lung carcinoma other hsa-mir-662 "Squamous Cell Carcinoma, Lung" 29571988 MiR-192 and miR-662 enhance chemoresistance and invasiveness of squamous cell lung carcinoma other hsa-mir-92a Neoplasms [unspecific] 29574928 Our results show that miR-92a possesses a cell-type dependent function other hsa-mir-19a "Carcinoma, Gallbladder" 29575299 The PLGF/c-MYC/miR-19a axis promotes metastasis and stemness in gallbladder cancer. other hsa-mir-146a Osteoarthritis 29575548 miR-146a may be used to counter both aging-associated OA and mechanical injury-/inflammation-induced PTOA other hsa-mir-155 Rheumatoid Arthritis 29575671 Rituximab may cause increased hepatitis C virus viremia in rheumatoid arthritis patients through declining exosomal microRNA-155 other hsa-mir-34a "Carcinoma, Gastric" 29577459 "abnormal glycolysis was relieved by ASIV via regulation of the expressions of LDHA, p53, TIGAR, MCT1, MCT4, HIF-1¦Á, CD147, and miRNA-34a" other hsa-mir-34a Toxic Encephalopathy 29578002 microRNA-34a could improve anesthesia-induced cognitive dysfunction by suppressing cell apoptosis and recovering the expression of genes associated with the MAPK/ERK signaling pathway other hsa-mir-34a Hypoxia 29581146 Inhibition of miR-34a-5p alleviates hypoxia-reoxygenation injury by enhancing autophagy in steatotic hepatocytes other hsa-mir-23a Renal Fibrosis 29582582 miRNA-23a/27a attenuates muscle atrophy and renal fibrosis through muscle-kidney crosstalk. other hsa-mir-27a Renal Fibrosis 29582582 miRNA-23a/27a attenuates muscle atrophy and renal fibrosis through muscle-kidney crosstalk. other hsa-mir-214 Heart Failure 29584819 "ROCR acted as a microRNA-214 sponge to release PTEN, which blocked activation of the PI3 kinase/Akt pathway to inhibit cardiomyocyte proliferation and ROCR may be a novel therapeutic target for preventing and treating heart failure" other hsa-let-7i Colon Neoplasms 29588449 "Available gene expression data allowed us to associate miR-30b expression with axon guidance and let-7i expression with cell adhesion, migration, and motility" other hsa-mir-30b Colon Neoplasms 29588449 "Available gene expression data allowed us to associate miR-30b expression with axon guidance and let-7i expression with cell adhesion, migration, and motility" other hsa-mir-10b Breast Ductal Carcinoma 29599829 "miR-10b-positive expression was correlated with the expression of ER-¦Á, Her-2 and the molecular subtypes of early invasive ductal carcinoma of the breast" other hsa-let-7a Monocytic Leukemia 29599918 FC-99 ameliorates sepsis-induced liver dysfunction by modulating monocyte/macrophage differentiation via Let-7a related monocytes apoptosis. other hsa-mir-146 Inflammation 29601548 "the NF-¦ÊB-miR-146 and NF-¦ÊB-miR-155 networks fine-tune the activity, intensity, and duration of inflammation, while the NF-¦ÊB-miR-21 and NF-¦ÊB-miR-181b-1 amplifying loops link inflammation to cancer" other hsa-mir-155 Inflammation 29601548 "the NF-¦ÊB-miR-146 and NF-¦ÊB-miR-155 networks fine-tune the activity, intensity, and duration of inflammation, while the NF-¦ÊB-miR-21 and NF-¦ÊB-miR-181b-1 amplifying loops link inflammation to cancer" other hsa-mir-181b Neoplasms [unspecific] 29601548 "the NF-¦ÊB-miR-146 and NF-¦ÊB-miR-155 networks fine-tune the activity, intensity, and duration of inflammation, while the NF-¦ÊB-miR-21 and NF-¦ÊB-miR-181b-2 amplifying loops link inflammation to cancer" other hsa-mir-21 Neoplasms [unspecific] 29601548 "the NF-¦ÊB-miR-146 and NF-¦ÊB-miR-155 networks fine-tune the activity, intensity, and duration of inflammation, while the NF-¦ÊB-miR-21 and NF-¦ÊB-miR-181b-3 amplifying loops link inflammation to cancer" other hsa-mir-141 Neoplasms [unspecific] 29602800 The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis. other hsa-mir-200a Neoplasms [unspecific] 29602800 The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis. other hsa-mir-200b Neoplasms [unspecific] 29602800 The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis. other hsa-mir-200c Neoplasms [unspecific] 29602800 The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis. other hsa-mir-429 Neoplasms [unspecific] 29602800 The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis. other hsa-mir-566 "Carcinoma, Renal Cell" 29604591 miR-566 functions as an oncogene and a potential biomarker for prognosis in renal cell carcinoma. other hsa-mir-31 Wound Healing 29605672 "these findings identify miR-31 as an important cell-autonomous mediator during the transition from inflammation to re-epithelialization phases of wound healing, suggesting a therapeutic potential for miR-31 in skin injury repair" other hsa-mir-181a Vascular Disease [unspecific] 29608244 microRNA-181a inhibits ocular neovascularization by interfering with vascular endothelial growth factor expression. other hsa-mir-146a Alzheimer Disease 29615954 Microbiome-Mediated Upregulation of MicroRNA-146a in Sporadic Alzheimer's Disease other hsa-mir-150 Age-Related Macular Degeneration 29618664 miR-150 as pathogenic in AMD and provide potentially novel molecular insights into diseases of aging other hsa-mir-642a "Carcinoma, Breast" 29620153 we examined the effects of synthetic miR-762 and miR-642a-3p inhibitors on SAHA-induced downregulation of Her2/neu and SAHA-induced apoptosis and PARP cleavage in BT474 cells other hsa-mir-762 "Carcinoma, Breast" 29620153 we examined the effects of synthetic miR-762 and miR-642a-3p inhibitors on SAHA-induced downregulation of Her2/neu and SAHA-induced apoptosis and PARP cleavage in BT474 cells other hsa-mir-210 Mitochondrial Metabolism Disease 29621777 Loading MiR-210 in Endothelial Progenitor Cells Derived Exosomes Boosts Their Beneficial Effects on Hypoxia/Reoxygeneation-Injured Human Endothelial Cells via Protecting Mitochondrial Function other hsa-mir-20a Glioblastoma 29625108 "The findings of the current study demonstrate presence of the IDH1 R132H mutation in primary human glioblastoma cell lines with upregulated HIF-1¦Á expression, downregulating c-MYC activity and resulting in a consequential decrease in miR-20a, which is responsible for cell proliferation and resistance to standard temozolomide treatment" other hsa-mir-20a Glioma 29625108 Oncogenic MicroRNA-20a is downregulated by the HIF-1¦Á/c-MYC pathway in IDH1 R132H-mutant glioma other hsa-mir-378 Fatty Liver [unspecific] 29625129 A negative feedback loop between microRNA-378 and Nrf1 promotes the development of hepatosteatosis in mice treated with a high fat diet. other hsa-mir-155 "Carcinoma, Cervical" 29627439 MiR-155-5p inhibits PDK1 and promotes autophagy via the mTOR pathway in cervical cancer. other hsa-mir-21 Alzheimer Disease 29635890 "miR-21 can exert protective roles in AD, which might be dependent on PDCD4/PI3K/AKT/GSK-3¦Â signaling pathway in vitro" other hsa-mir-21 Neuroblastoma 29635890 MiR-21 attenuates apoptosis-triggered by amyloid-¦Â via modulating PDCD4/PI3K/AKT/GSK-3¦Â pathway in SH-SY5Y cells other hsa-mir-17 Feingold Syndrome 29636449 Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models. other hsa-mir-18 Feingold Syndrome 29636449 Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models. other hsa-mir-19a Feingold Syndrome 29636449 Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models. other hsa-mir-19b-1 Feingold Syndrome 29636449 Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models. other hsa-mir-20a Feingold Syndrome 29636449 Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models. other hsa-mir-92-1 Feingold Syndrome 29636449 Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models. other hsa-mir-1 Neoplasms [unspecific] 29642568 "A single sub-lethal dose of irradiation has been shown to result in compensatory up-regulation of the myocardial connexin-43 (Cx43), activation of the protein kinase C (PKC) signaling along with the decline of microRNA (miR)-1 and an increase of miR-21 levels in the left ventricle (LV)" other hsa-mir-21 Neoplasms [unspecific] 29642568 Irradiation-Induced Cardiac Connexin-43 and miR-21 Responses Are Hampered by Treatment with Atorvastatin and Aspirin other hsa-let-7 Neoplasms [unspecific] 29644076 These observations emphasize the central importance of IGF signaling pathways in the mediation of intragenomic conflicts over embryonic growth and identify possible targets for therapeutic interventions in cancer other hsa-mir-2113 Proliferative Diabetic Retinopathy 29654764 Rg1 inhibits high glucose-induced mesenchymal activation and fibrosis via regulating miR-2113/RP11-982M15.8/Zeb1 pathway. other hsa-mir-200c Colorectal Carcinoma 29656186 DCLK1 plays an important role in colorectal cancer tumorgenesis through the regulation of miR-200c. other hsa-mir-146a "Leukemia, Myeloid, Acute" 29657293 miR-146 (146a and 146b) and miR-155 are among the first and most studied miRs for their multiple roles in the control of the innate and adaptive immune processes and for their deregulation and oncogenic role in some tumors other hsa-mir-146b "Leukemia, Myeloid, Acute" 29657293 miR-146 (146a and 146b) and miR-155 are among the first and most studied miRs for their multiple roles in the control of the innate and adaptive immune processes and for their deregulation and oncogenic role in some tumors other hsa-let-7 Ovarian Neoplasms 29658612 let-7d-3p is associated with apoptosis and response to neoadjuvant chemotherapy in ovarian cancer other hsa-mir-21 Atherosclerosis 29659130 its involvement in the complex development of atherosclerosis has yet to be ascertained other hsa-mir-21 Cardiovascular Diseases [unspecific] 29659130 "MicroRNA-21 (miR-21) is a short, non-coding RNA that has been implicated in cardiovascular diseases including proliferative vascular disease and ischaemic heart disease" other hsa-mir-21 Vascular Disease [unspecific] 29659130 "MicroRNA-21 (miR-21) is a short, non-coding RNA that has been implicated in cardiovascular diseases including proliferative vascular disease and ischaemic heart disease" other hsa-mir-449a Bladder Neoplasms 29659560 Androgen Receptor Is Inactivated and Degraded in Bladder Cancer Cells by Phenyl Glucosamine via miR-449a Restoration. other hsa-mir-214 Endometriosis 29660008 Exosomal miR-214 from endometrial stromal cells inhibits endometriosis fibrosis. other hsa-mir-148a "Carcinoma, Pancreatic Ductal" 29660218 Molecular pathogenesis of pancreatic ductal adenocarcinoma: Impact of passenger strand of pre-miR-148a on gene regulation. other hsa-mir-30e Cholangiocarcinoma 29662654 Extracellular vesicle-encapsulated miR-30e suppresses cholangiocarcinoma cell invasion and migration via inhibiting epithelial-mesenchymal transition other hsa-mir-200c "Carcinoma, Breast, Triple Negative" 29666469 the new p53/miR-30a/ZEB2 axis controls tumor cell invasion and distal spreading and impinges upon miR-200c expression other hsa-mir-10b "Carcinoma, Renal Cell, Clear-Cell" 29672315 MicroRNA-10b Promotes Apoptosis via JNK Pathway in Clear Cell Renal Cell Carcinoma other hsa-mir-122 Chronic Hepatitis C 29672716 "miR-122 does not impact recognition of the HCV genome by innate sensors of RNA but rather protects the 5' end from the cellular pyrophosphatases, DOM3Z and DUSP11" other hsa-mir-155 "Carcinoma, Gastric" 29675003 Role of microRNAs and Exosomes in Helicobacter pylori and Epstein-Barr Virus Associated Gastric Cancers other hsa-mir-155 Gastric Neoplasms 29675003 Role of microRNAs and Exosomes in Helicobacter pylori and Epstein-Barr Virus Associated Gastric Cancers other hsa-mir-590 Influenza 29677213 IFN-¦Ë and microRNAs are important modulators of the pulmonary innate immune response against influenza A (H1N2) infection in pigs other hsa-mir-143 "Diabetes Mellitus, Type 2" 29680463 "we will summarize the involvement of miR-143 in regulating the development of T2DM and the underlying mechanisms for potential diagnosis, prevention, and treatments, including exercise intervention for T2DM by targeting miR-143" other hsa-mir-19a Multiple Myeloma 29687521 "Signal pathways, diseases, and functions associated with the miR-19a/92a cluster and the use of berberine to modulate the expression of this cluster in multiple myeloma cells." other hsa-mir-92a Multiple Myeloma 29687521 "Signal pathways, diseases, and functions associated with the miR-19a/92a cluster and the use of berberine to modulate the expression of this cluster in multiple myeloma cells." other hsa-mir-199a Arteriovenous Malformations of the Brain 29689389 "Functional annotation suggested that 15 of the predicted miRNA-targeted genes were involved in vascular endothelial growth factor signaling, in which 3 critical miRNAs were involved: miR-7-5p, miR-199a-5p, and miR-200b-3p" other hsa-mir-200b Arteriovenous Malformations of the Brain 29689389 "Functional annotation suggested that 15 of the predicted miRNA-targeted genes were involved in vascular endothelial growth factor signaling, in which 3 critical miRNAs were involved: miR-7-5p, miR-199a-5p, and miR-200b-3p" other hsa-mir-7 Arteriovenous Malformations of the Brain 29689389 "Functional annotation suggested that 15 of the predicted miRNA-targeted genes were involved in vascular endothelial growth factor signaling, in which 3 critical miRNAs were involved: miR-7-5p, miR-199a-5p, and miR-200b-3p" other hsa-mir-181a "Carcinoma, Renal Cell" 29693121 microRNA?181a?5p functions as an oncogene in renal cell carcinoma. other hsa-mir-214 "Adenocarcinoma, Lung" 29693173 TWIST1 upregulates miR-214 to promote epithelial-to-mesenchymal transition and metastasis in lung adenocarcinoma. other hsa-mir-155 Rheumatoid Arthritis 29693176 PU.1 attenuates TNF?¦Á?induced proliferation and cytokine release of rheumatoid arthritis fibroblast?like synoviocytes by regulating miR?155 activity. other hsa-mir-604 Gastric Neoplasms 29693274 miR-604 could become a new indicator in the diagnosis of drug-resistant GC and may be used to investigate the pathogenesis of resistance in GC other hsa-mir-339 Acute Pancreatitis 29693276 MicroRNA-339-3p alleviates inflammation and edema and suppresses pulmonary microvascular endothelial cell apoptosis in mice with severe acute pancreatitis-associated acute lung injury by regulating Anxa3 via the Akt/mTOR signaling pathway. other hsa-mir-139 "Carcinoma, Hepatocellular" 29693285 Higher variety and quantity of microRNA-139-5p isoforms confer suppressive role in hepatocellular carcinoma. other hsa-mir-383 Coronary Artery Disease 29693751 The anti-inflammatory effect of microRNA-383-3p interacting with IL1R2 against homocysteine-induced endothelial injury in rat coronary arteries. other hsa-mir-196a "Carcinoma, Renal Cell, Clear-Cell" 29695508 "ANKHD1 positively drives ccRCC cell mitosis via binding to and suppressing mainly miR-29a and to a lesser degree via miR-196a/205, leading to up-regulation in proliferative genes such as CCDN1" other hsa-mir-205 "Carcinoma, Renal Cell, Clear-Cell" 29695508 "ANKHD1 positively drives ccRCC cell mitosis via binding to and suppressing mainly miR-29a and to a lesser degree via miR-196a/205, leading to up-regulation in proliferative genes such as CCDN1" other hsa-mir-29a "Carcinoma, Renal Cell, Clear-Cell" 29695508 "ANKHD1 positively drives ccRCC cell mitosis via binding to and suppressing mainly miR-29a and to a lesser degree via miR-196a/205, leading to up-regulation in proliferative genes such as CCDN1" other hsa-mir-221 Infection [unspecific] 29698854 Avian leukosis virus subgroup J promotes cell proliferation and cell cycle progression through miR-221 by targeting CDKN1B. other hsa-mir-200b "Carcinoma, Breast" 29702103 The miR-200b/200a/429 cluster prevents metastasis and induces dormancy in a murine claudin-low mammary tumor cell line. other hsa-mir-200c "Carcinoma, Breast" 29702103 The miR-200b/200a/429 cluster prevents metastasis and induces dormancy in a murine claudin-low mammary tumor cell line. other hsa-mir-429 "Carcinoma, Breast" 29702103 The miR-200b/200a/429 cluster prevents metastasis and induces dormancy in a murine claudin-low mammary tumor cell line. other hsa-mir-34c Becker Muscular Dystrophy 29703249 miR-708-5p and miR-34c-5p are involved in nNOS regulation in dystrophic context. other hsa-mir-708 Becker Muscular Dystrophy 29703249 miR-708-5p and miR-34c-5p are involved in nNOS regulation in dystrophic context. other hsa-mir-145 Atherosclerosis 29710501 Microrna-145 accelerates the inflammatory reaction through activation of NF-¦ÊB signaling in atherosclerosis cells and mice. other hsa-mir-29c Colorectal Carcinoma 29710520 Inhibition of miR-29c could dramatically reverse Astragaloside IV-induced B7-H3 decrease and cell growth arrest other hsa-mir-126 "Diabetes Mellitus, Type 2" 29710530 Resveratrol improves uric acid-induced pancreatic ¦Â-cells injury and dysfunction through regulation of miR-126. other hsa-mir-125b "Carcinoma, Lung, Non-Small-Cell" 29722542 Repolarization of Tumor-Associated Macrophages in a Genetically Engineered Nonsmall Cell Lung Cancer Model by Intraperitoneal Administration of Hyaluronic Acid-Based Nanoparticles Encapsulating MicroRNA-125b. other hsa-mir-142 Asthma 29722559 miR-142-3p is associated with aberrant WNT signaling during airway remodeling in asthma. other hsa-mir-222 Glioblastoma 29723631 "the microRNAs (miRNAs) miR-27a, miR-222, miR-449 was observed after exposure to curcumin" other hsa-mir-27a Glioblastoma 29723631 "the microRNAs (miRNAs) miR-27a, miR-222, miR-449 was observed after exposure to curcumin" other hsa-mir-449 Glioblastoma 29723631 "the microRNAs (miRNAs) miR-27a, miR-222, miR-449 was observed after exposure to curcumin" other hsa-mir-486 Hyperlipidemia 29725814 Inhibition of miR-486 and miR-92a decreases liver and plasma cholesterol levels by modulating lipid-related genes in hyperlipidemic hamsters. other hsa-mir-92a Hyperlipidemia 29725814 Inhibition of miR-486 and miR-92a decreases liver and plasma cholesterol levels by modulating lipid-related genes in hyperlipidemic hamsters. other hsa-mir-1910 Colorectal Carcinoma 29729381 STAT1-mediated upregulation of lncRNA LINC00174 functions a ceRNA for miR-1910-3p to facilitate colorectal carcinoma progression through regulation of TAZ. other hsa-mir-186 Chondrosarcoma 29730230 Resistin facilitates VEGF-C-associated lymphangiogenesis by inhibiting miR-186 in human chondrosarcoma cells. other hsa-mir-21 "Adenocarcinoma, Lung" 29730429 Lung adenocarcinoma cell-derived exosomal miR-21 facilitates osteoclastogenesis. other hsa-mir-199 Cystic Fibrosis 29732561 Small RNA and transcriptome sequencing reveal the role of miR-199a-3p in inflammatory processes in cystic fibrosis airways. other hsa-mir-221 Atherosclerosis 29737876 MicroRNA-221/222 expression in atherosclerotic coronary artery plaque versus internal mammarian artery and in peripheral blood samples. other hsa-mir-222 Atherosclerosis 29737876 MicroRNA-221/222 expression in atherosclerotic coronary artery plaque versus internal mammarian artery and in peripheral blood samples. other hsa-mir-141 "Squamous Cell Carcinoma, Esophageal" 29738771 "MiR-141-3p is upregulated in esophageal squamous cell carcinoma and targets pleckstrin homology domain leucine-rich repeat protein phosphatase-2, a negative regulator of the PI3K/AKT pathway." other hsa-mir-1 "Muscular Dystrophy, Facioscapulohumeral" 29741619 Small noncoding RNAs in FSHD2 muscle cells reveal both DUX4- and SMCHD1-specific signatures. other hsa-mir-133a "Muscular Dystrophy, Facioscapulohumeral" 29741619 Small noncoding RNAs in FSHD2 muscle cells reveal both DUX4- and SMCHD1-specific signatures. other hsa-mir-206 "Muscular Dystrophy, Facioscapulohumeral" 29741619 Small noncoding RNAs in FSHD2 muscle cells reveal both DUX4- and SMCHD1-specific signatures. other hsa-mir-1 Ischemia-Reperfusion Injury 29741915 The role of microRNA-1 targeting of MAPK3 in myocardial ischemia-reperfusion injury in rats undergoing sevoflurane preconditioning via the PI3K/Akt pathway. other hsa-mir-380 Neoplasms [unspecific] 29743236 "2-hydroxyglutarate (2-HG) stabilizes hypoxia-inducible factor-2¦Á, which in turn activates the expression of miR-380-5p, a characterized microRNA against p53 expression" other hsa-mir-10a Atherosclerosis 29748186 miR-10a expression was negatively correlated to the progression of atherosclerosis in humans other hsa-mir-345 Prostate Neoplasms 29748958 Functional roles and potential clinical application of miRNA-345-5p in prostate cancer. other hsa-mir-25 Breast Neoplasms 29765562 A myriad of roles of miR-25 in health and disease. other hsa-mir-27a Bronchopneumonia 29772436 Tanshinone IIA ameliorates lipopolysaccharide-induced inflammatory response in bronchial epithelium cell line BEAS-2B by down-regulating miR-27a. other hsa-mir-199a "Carcinoma, Renal Cell, Clear-Cell" 29773428 MiR-199a-3p acts as a tumor suppressor in clear cell renal cell carcinoma. other hsa-mir-34a Chronic Inflammation 29773953 miR-34a-mediated regulation of XIST in female cells under inflammation. other hsa-mir-1 Myocardial Infarction 29775643 Myocardial infarction-induced hippocampal microtubule damage by cardiac originating microRNA-1 in mice. other hsa-mir-135a Cardiac Fibrosis 29775892 MicroRNA-135a inhibits cardiac fibrosis induced by isoproterenol via TRPM7 channel. other hsa-mir-24 Hypertrophy 29786048 Cardiac Hypertrophy is Positively Regulated by MicroRNA?24 in Rats other hsa-mir-200b Cardiac Fibrosis 29786779 DNMT3A controls miR-200b in cardiac fibroblast autophagy and cardiac fibrosis. other hsa-mir-30e Sepsis 29787988 MicroRNA-30e promotes hepatocyte proliferation and inhibits apoptosis in cecal ligation and puncture-induced sepsis through the JAK/STAT signaling pathway by binding to FOSL2. other hsa-let-7b Monocytic Leukemia 29790117 Regulatory roles of miR-155 and let-7b on the expression of inflammation-related genes in THP-1 cells: effects of fatty acids. other hsa-mir-155 Monocytic Leukemia 29790117 Regulatory roles of miR-155 and let-7b on the expression of inflammation-related genes in THP-1 cells: effects of fatty acids. other hsa-mir-146a Neoplasms [unspecific] 29800683 "We will specifically focus on three miRNAs that have been shown to regulate different aspects of T cell biology in both physiological and pathological conditions, namely miR-155, miR-146a and miR-181a" other hsa-mir-155 Neoplasms [unspecific] 29800683 "We will specifically focus on three miRNAs that have been shown to regulate different aspects of T cell biology in both physiological and pathological conditions, namely miR-155, miR-146a and miR-181a" other hsa-mir-181a Neoplasms [unspecific] 29800683 "We will specifically focus on three miRNAs that have been shown to regulate different aspects of T cell biology in both physiological and pathological conditions, namely miR-155, miR-146a and miR-181a" other hsa-mir-15a Prostate Neoplasms 29803177 miR-15a/miR-16 cluster inhibits invasion of prostate cancer cells by suppressing TGF-¦Â signaling pathway. other hsa-mir-16 Prostate Neoplasms 29803177 miR-15a/miR-16 cluster inhibits invasion of prostate cancer cells by suppressing TGF-¦Â signaling pathway. other hsa-mir-204 "Carcinoma, Renal Cell, Clear-Cell" 29805586 hsa-miR-204 and hsa-miR-218 may be involved in the pathogenesis of ccRCC other hsa-mir-218 "Carcinoma, Renal Cell, Clear-Cell" 29805586 hsa-miR-204 and hsa-miR-218 may be involved in the pathogenesis of ccRCC other hsa-mir-106a Colorectal Carcinoma 29805629 MicroRNA-106a inhibits cell proliferation and induces apoptosis in colorectal cancer cells. other hsa-mir-127 Glioma 29805677 Tudor-staphylococcal nuclease regulates the expression and biological function of alkylglycerone phosphate synthase via nuclear factor-¦ÊB and microRNA-127 in human glioma U87MG cells. other hsa-mir-181b "Stroke, Ischemic" 29807144 Neuroprotective effects of isosteviol sodium through increasing CYLD by the downregulation of miRNA-181b. other hsa-mir-21 Lung Fibrosis 29843043 Resveratrol inhibits pulmonary fibrosis by regulating miR-21 through MAPK/AP-1 pathways. other hsa-mir-221 Retinoblastoma 29843209 Upregulated miR-221/222 promotes cell proliferation and invasion and is associated with invasive features in retinoblastoma. other hsa-mir-222 Retinoblastoma 29843209 Upregulated miR-221/222 promotes cell proliferation and invasion and is associated with invasive features in retinoblastoma. other hsa-mir-206 Rhabdomyosarcoma 29844345 "SNAIL silencing induces myogenic differentiation by upregulation of myogenic factors and muscle-specific microRNAs, such as miR-206." other hsa-mir-143 Liver Neoplasms 29844837 The mechanism of miR-143 inducing apoptosis of liver carcinoma cells through regulation of the NF-¦ÊB pathway. other hsa-mir-133 Acute Myocardial Infarction 29845217 "By searching the mir2disease database, four miRNAs associated with AMI were identified, including hsa-miR-21, hsa-miR-133, hsa-miR-29 and hsa-miR-30c." other hsa-mir-21 Acute Myocardial Infarction 29845217 "By searching the mir2disease database, four miRNAs associated with AMI were identified, including hsa-miR-21, hsa-miR-133, hsa-miR-29 and hsa-miR-30c." other hsa-mir-29 Acute Myocardial Infarction 29845217 "By searching the mir2disease database, four miRNAs associated with AMI were identified, including hsa-miR-21, hsa-miR-133, hsa-miR-29 and hsa-miR-30c." other hsa-mir-30c Acute Myocardial Infarction 29845217 "By searching the mir2disease database, four miRNAs associated with AMI were identified, including hsa-miR-21, hsa-miR-133, hsa-miR-29 and hsa-miR-30c." other hsa-mir-24 Aneurysmal Subarachnoid Hemorrhage 29845232 Upregulation of microRNA?24 causes vasospasm following subarachnoid hemorrhage by suppressing the expression of endothelial nitric oxide synthase. other hsa-mir-16 Rheumatic Myocarditis 29845432 "significant downregulation of hsa-miR-16-5p, hsa-miR-223-3p and hsa-miR-92a-3p in children with rheumatic carditis" other hsa-mir-223 Rheumatic Myocarditis 29845432 "significant downregulation of hsa-miR-16-5p, hsa-miR-223-3p and hsa-miR-92a-3p in children with rheumatic carditis" other hsa-mir-92a Rheumatic Myocarditis 29845432 "significant downregulation of hsa-miR-16-5p, hsa-miR-223-3p and hsa-miR-92a-3p in children with rheumatic carditis" other hsa-mir-130a "Diabetes Mellitus, Type 2" 29855803 Aerobic training improves platelet function in type 2 diabetic patients: role of microRNA-130a and GPIIb. other hsa-mir-22 Neoplasms [unspecific] 29856481 "Triose-phosphate isomerase is a novel target of miR-22 and miR-28, with implications in tumorigenesis." other hsa-mir-28 Neoplasms [unspecific] 29856481 "Triose-phosphate isomerase is a novel target of miR-22 and miR-28, with implications in tumorigenesis." other hsa-mir-210 "Carcinoma, Hepatocellular" 29858059 Hepatocellular Carcinoma Cell-Secreted Exosomal MicroRNA-210 Promotes Angiogenesis In?Vitro and In?Vivo. other hsa-mir-326 Lupus Nephritis 29858063 MicroRNA-326?Upregulates B Cell Activity and Autoantibody Production in Lupus Disease of MRL/lpr Mice. other hsa-mir-449a "Carcinoma, Lung, Non-Small-Cell" 29858080 Targeting Nicotinamide N-Methyltransferase and miR-449a in EGFR-TKI-Resistant Non-Small-Cell Lung Cancer Cells. other hsa-mir-122 Muscle Diseases [unspecific] 29858088 miR-24 and miR-122 Negatively Regulate the Transforming Growth Factor-¦Â/Smad Signaling Pathway in Skeletal Muscle Fibrosis. other hsa-mir-24 Muscle Diseases [unspecific] 29858088 miR-24 and miR-122 Negatively Regulate the Transforming Growth Factor-¦Â/Smad Signaling Pathway in Skeletal Muscle Fibrosis. other hsa-mir-132 Huntington Disease 29858092 Supplemental Treatment for Huntington's Disease with miR-132 that Is Deficient in Huntington's Disease Brain. other hsa-mir-182 Parkinson Disease 29858093 miR-182-5p and miR-183-5p Act as GDNF Mimics in Dopaminergic Midbrain Neurons. other hsa-mir-183 Parkinson Disease 29858093 miR-182-5p and miR-183-5p Act as GDNF Mimics in Dopaminergic Midbrain Neurons. other hsa-mir-483 Neoplasms [unspecific] 29867024 The Glucose-Regulated MiR-483-3p Influences Key Signaling Pathways in Cancer. other hsa-mir-101 Gastric Neoplasms 29872807 "miR-101-3p, miR-16-5p and miR-19b-3p were found to be located in the nuclei of MGC803 cells with granulated shapes" other hsa-mir-16 Gastric Neoplasms 29872807 "miR-101-3p, miR-16-5p and miR-19b-3p were found to be located in the nuclei of MGC803 cells with granulated shapes" other hsa-mir-19b Gastric Neoplasms 29872807 "miR-101-3p, miR-16-5p and miR-19b-3p were found to be located in the nuclei of MGC803 cells with granulated shapes" other hsa-mir-106b Allergic Asthma 29875322 "This method identified 5 Th2-related miRs (mir27b, mir206, mir106b, mir203, and mir23b) whose antagonization led to a sharp reduction of the Th2 phenotype" other hsa-mir-203 Allergic Asthma 29875322 "This method identified 5 Th2-related miRs (mir27b, mir206, mir106b, mir203, and mir23b) whose antagonization led to a sharp reduction of the Th2 phenotype" other hsa-mir-206 Allergic Asthma 29875322 "This method identified 5 Th2-related miRs (mir27b, mir206, mir106b, mir203, and mir23b) whose antagonization led to a sharp reduction of the Th2 phenotype" other hsa-mir-23b Allergic Asthma 29875322 "This method identified 5 Th2-related miRs (mir27b, mir206, mir106b, mir203, and mir23b) whose antagonization led to a sharp reduction of the Th2 phenotype" other hsa-mir-27b Allergic Asthma 29875322 "This method identified 5 Th2-related miRs (mir27b, mir206, mir106b, mir203, and mir23b) whose antagonization led to a sharp reduction of the Th2 phenotype" other hsa-mir-7 Glioma 29877083 Inhibition of the Proliferation and Invasion of C6 Glioma Cells by Tricin via the Upregulation of Focal-Adhesion-Kinase-Targeting MicroRNA-7. other hsa-mir-208a Cardiac Myocyte Injury 29877301 MicroRNA-208a Correlates Apoptosis and Oxidative Stress Induced by H2O2 through Protein Tyrosine Kinase/Phosphatase Balance in Cardiomyocytes. other hsa-mir-100 "Squamous Cell Carcinoma, Head and Neck" 29880533 "the expression of MIR100HG-embedded microRNA, miR-100, was significantly associated with overall survival in an independent cohort of HNSCC cases " other hsa-mir-342 "Leukemia, Myeloid, Acute" 29880818 Aberrant mannosylation profile and FTX/miR-342/ALG3-axis contribute to development of drug resistance in acute myeloid leukemia. other hsa-mir-514b Colorectal Carcinoma 29880874 The distinct role of strand-specific miR-514b-3p and miR-514b-5p in colorectal cancer metastasis. other hsa-mir-139 Colorectal Carcinoma 29883634 miR-139 could be a potential biomarker for diagnosis of digestive system tumors especially colorectal cancer other hsa-mir-21a Spinal Cord Injuries 29883711 MicroRNA-21a-5p promotes fibrosis in spinal fibroblasts after mechanical trauma. other hsa-mir-145 Diabetic Retinopathy 29883722 MicroRNA-145 attenuates high glucose-induced oxidative stress and inflammation in retinal endothelial cells through regulating TLR4/NF-¦ÊB signaling. other hsa-mir-187 "Carcinoma, Bladder" 29883941 "Oncogene miR-187-5p is associated with cellular proliferation, migration, invasion, apoptosis and an increased risk of recurrence in bladder cancer." other hsa-mir-410 Cardiomyopathy 29884823 MicroRNA-410-5p exacerbates high-fat diet-induced cardiac remodeling in mice in an endocrine fashion. other hsa-mir-1 Atrial Fibrillation 29885959 Increased right atrial appendage apoptosis is associated with differential regulation of candidate MicroRNAs 1 and 133A in patients who developed atrial fibrillation after cardiac surgery. other hsa-mir-133a Atrial Fibrillation 29885959 Increased right atrial appendage apoptosis is associated with differential regulation of candidate MicroRNAs 1 and 133A in patients who developed atrial fibrillation after cardiac surgery. other hsa-mir-31 "Colitis, Ulcerative" 29889228 "Our data suggest a role for TSLP in promoting mucosal healing and regulating inflammation in UC, whereas miR-31 can directly block this effect" other hsa-mir-425 Myocardial Infarction 29890520 Overcoming Heparin-Associated RT-qPCR Inhibition and Normalization Issues for microRNA Quantification in Patients with Acute Myocardial Infarction. other hsa-mir-197 "Lymphoma, Large B-Cell, Diffuse" 29890998 Clinicopathologic implication of microRNA-197 in diffuse large B cell lymphoma. other hsa-mir-30 "Carcinoma, Breast" 29894647 MicroRNA-30 mediates cell invasion and metastasis in breast cancer. other hsa-mir-200c Lung Neoplasms 29898461 miR-200c can be used as a highly sensitive molecular staging biomarker that will enhance nodal staging of lung cancer other hsa-mir-210 Prostate Neoplasms 29901117 Effects of microRNA?210 on the diagnosis and treatment of prostate cancer. other hsa-mir-122 Atrial Fibrillation 29901138 Upregulation of miR?122 is associated with cardiomyocyte apoptosis in atrial fibrillation. other hsa-mir-381 "Carcinoma, Hepatocellular" 29904424 Expression and role of VEGFA and miR-381 in portal vein tumor thrombi in patients with hepatocellular carcinoma. other hsa-mir-124a Kidney Diseases [unspecific] 29904949 Combination with miR-124a improves the protective action of BMSCs in rescuing injured rat podocytes from abnormal apoptosis and autophagy. other hsa-mir-203 "Carcinoma, Hepatocellular" 29906128 MicroRNA-203 Increases Cell Radiosensitivity via Directly Targeting Bmi-1 in Hepatocellular Carcinoma. other hsa-mir-199b Pulmonary Hypertension 29906222 "This study describes a novel microRNA signature of adaptive right ventricular hypertrophy, with particular attention to miR-199b and miR-29a" other hsa-mir-29a Pulmonary Hypertension 29906222 "This study describes a novel microRNA signature of adaptive right ventricular hypertrophy, with particular attention to miR-199b and miR-29a" other hsa-mir-505 Glioblastoma 29906532 Combination with TMZ and miR-505 inhibits the development of glioblastoma by regulating the WNT7B/Wnt/¦Â-catenin signaling pathway. other hsa-mir-181a "Carcinoma, Breast" 29907248 Micro-RNA-181a suppresses progestin-promoted breast cancer cell growth. other hsa-mir-98 Myocardial Infarction 29913449 Pre-Treatment with Melatonin Enhances Therapeutic Efficacy of Cardiac Progenitor Cells for Myocardial Infarction. other hsa-mir-6853 "Diabetes Mellitus, Type 2" 29916530 miR?6835?3p regulates the function of pancreatic islet cells by modulating the expression of AdipoR1. other hsa-mir-184 Osteosarcoma 29916553 Regulatory effects of microRNA?184 on osteosarcoma via the Wnt/¦Â?catenin signaling pathway. other hsa-mir-26a Acute Cerebral Infarction 29917203 MiRNA-26a promotes angiogenesis in a rat model of cerebral infarction via PI3K/AKT and MAPK/ERK pathway. other hsa-mir-499 Cardiovascular Diseases [unspecific] 29920798 Unlockable Nanocomplexes with Self-Accelerating Nucleic Acid Release for Effective Staged Gene Therapy of Cardiovascular Diseases. other hsa-mir-107 "Carcinoma, Breast" 29921315 Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages. other hsa-mir-15b "Carcinoma, Breast" 29921315 Expression of ID4 protein in breast cancer cells induces reprogramming of tumour-associated macrophages. other hsa-let-7g Lung Neoplasms 29923982 "Three miRNAs (let-7g-5p, miR-143-3p, and miR-374a-5p) were associated with postoperative recurrence in both microarray and TCGA data sets" other hsa-mir-143 Lung Neoplasms 29923982 "Three miRNAs (let-7g-5p, miR-143-3p, and miR-374a-5p) were associated with postoperative recurrence in both microarray and TCGA data sets" other hsa-mir-374a Lung Neoplasms 29923982 "Three miRNAs (let-7g-5p, miR-143-3p, and miR-374a-5p) were associated with postoperative recurrence in both microarray and TCGA data sets" other hsa-mir-320b Acute Ischemic Stroke 29926387 Unique MicroRNAs Signature of Lymphocyte of Yang and Yin Syndromes in Acute Ischemic Stroke Patients. other hsa-mir-93 Acute Ischemic Stroke 29926387 Unique MicroRNAs Signature of Lymphocyte of Yang and Yin Syndromes in Acute Ischemic Stroke Patients. other hsa-mir-888 Colorectal Carcinoma 29928331 miR-888 functions as an oncogene and predicts poor prognosis in colorectal cancer. other hsa-mir-148a "Carcinoma, Lung, Non-Small-Cell" 29928367 miR-148a may regulate a panel of tumor-associated proteins to suppress metastasis in NSCLC other hsa-mir-130a Diabetic Peripheral Neuropathy 29932869 Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy. other hsa-mir-28 Diabetic Peripheral Neuropathy 29932869 Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy. other hsa-mir-31a Diabetic Peripheral Neuropathy 29932869 Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy. other hsa-mir-496 "Carcinoma, Oropharyngeal" 29935424 Human papillomavirus 16 E6 modulates the expression of miR-496 in oropharyngeal cancer. other hsa-mir-26b Ischemic Diseases [unspecific] 29937716 MicroRNA-26b Regulates the Microglial Inflammatory Response in Hypoxia/Ischemia and Affects the Development of Vascular Cognitive Impairment. other hsa-mir-126 Fabry Disease 29937989 "miR-199a-5p, and miR-126-3p are involved in endothelial dysfunction and miR-423-5p and miR-451a in myocardial remodeling" other hsa-mir-199a Fabry Disease 29937989 "miR-199a-5p, and miR-126-3p are involved in endothelial dysfunction and miR-423-5p and miR-451a in myocardial remodeling" other hsa-mir-423 Fabry Disease 29937989 "miR-199a-5p, and miR-126-3p are involved in endothelial dysfunction and miR-423-5p and miR-451a in myocardial remodeling" other hsa-mir-451a Fabry Disease 29937989 "miR-199a-5p, and miR-126-3p are involved in endothelial dysfunction and miR-423-5p and miR-451a in myocardial remodeling" other hsa-mir-383 Colorectal Carcinoma 29938829 MicroRNA-383 acts as a tumor suppressor in colorectal cancer by modulating CREPT/RPRD1B expression. other hsa-mir-7 "Carcinoma, Breast" 29941867 Association of microRNA-7 and its binding partner CDR1-AS with the prognosis and prediction of 1st-line tamoxifen therapy in breast cancer. other hsa-mir-205 Ovarian Neoplasms 29943422 Tanshinone IIA induced cell apoptosis in ovarian carcinoma TOV-21G cells via direct upregulation of miR-205 other hsa-mir-198 "Carcinoma, Lung, Non-Small-Cell" 29943841 MicroRNA-198 inhibition of HGF/c-MET signaling pathway overcomes resistance to radiotherapy and induces apoptosis in human non-small-cell lung cancer. other hsa-mir-106a Gastric Neoplasms 29948558 Negative Regulation of Kruppel-Like Factor 4 on microRNA-106a at Upstream Transcriptional Level and the Role in Gastric Cancer Metastasis. other hsa-mir-19 Ischemia-Reperfusion Injury 29953651 MicroRNA-19 restores vascular endothelial cell function in lower limb ischemia-reperfusion injury through the KLF10-dependent TGF-¦Â1/Smad signaling pathway in rats. other hsa-mir-17 Gastric Neoplasms 29953965 MicroRNA-17 inhibition overcomes chemoresistance and suppresses epithelial-mesenchymal transition through a DEDD-dependent mechanism in gastric cancer. other hsa-mir-26a "Aortic Aneurysm, Abdominal" 29956734 MicroRNA?26a protects vascular smooth muscle cells against H2O2?induced injury through activation of the PTEN/AKT/mTOR pathway. other hsa-mir-361 Gastric Neoplasms 29960070 MiR-361-5p inhibits the mobility of gastric cancer cells through suppressing epithelial-mesenchymal transition via the Wnt/¦Â-catenin pathway. other hsa-mir-19b Ovarian Neoplasms 29963131 MicroRNA-19b promotes the migration and invasion of ovarian cancer cells by inhibiting the PTEN/AKT signaling pathway. other hsa-mir-202 "Carcinoma, Breast" 29963190 miR-202 acts as a potential tumor suppressor in breast cancer. other hsa-mir-140 Porcine Reproductive and Respiratory Syndrome Virus Infection 29969475 Utilizing host endogenous microRNAs to negatively regulate the replication of porcine reproductive and respiratory syndrome virus in MARC-145 cells. other hsa-mir-181 "Leukemia, Myeloid, Acute" 29969755 Circ-ANAPC7 is Upregulated in Acute Myeloid Leukemia and Appears to Target the MiR-181 Family. other hsa-mir-106b "Carcinoma, Bladder" 29970902 Identification of microR-106b as a prognostic biomarker of p53-like bladder cancers by ActMiR. other hsa-mir-155 Atherosclerosis 29977930 TRIF Regulates BIC/miR-155 via the ERK Signaling Pathway to Control the ox-LDL-Induced Macrophage Inflammatory Response. other hsa-mir-199a "Lymphoma, Mantle-Cell" 29979193 MiR-199a mediated the dissemination of human mantle cell lymphoma by interacting with the CCR7/CCL21 pair. other hsa-mir-142 Coronary Artery Disease 29979444 miR-142-3p and miR-17-5p might be potential targets for follow-up research in evaluating biomarkers of coronary artery disease other hsa-mir-17 Coronary Artery Disease 29979444 miR-142-3p and miR-17-5p might be potential targets for follow-up research in evaluating biomarkers of coronary artery disease other hsa-mir-132 Alzheimer Disease 29982852 MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways. other hsa-mir-181 Cardiovascular Diseases [unspecific] 29985373 In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge. other hsa-mir-135b Gastric Neoplasms 29985646 Helicobacter pylori-induced miR-135b-5p promotes cisplatin resistance in gastric cancer. other hsa-mir-196a "Carcinoma, Pancreatic" 29986379 miR-196a Is Able to Restore the Aggressive Phenotype of Annexin A1 Knock-Out in Pancreatic Cancer Cells by CRISPR/Cas9 Genome Editing. other hsa-mir-663 Neoplasms [unspecific] 29987196 "MiR-663, a MicroRNA Linked with Inflammation and Cancer That Is under the Influence of Resveratrol." other hsa-mir-101 "Adenocarcinoma, Esophageal" 29987600 Two miRNA ratios (miR-4521/miR-340-5p and miR-101-3p/miR-451a) that predicted the pathological response to neoadjuvant chemoradiotherapy were found to be associated with relapse-free survival other hsa-mir-340 "Adenocarcinoma, Esophageal" 29987600 Two miRNA ratios (miR-4521/miR-340-5p and miR-101-3p/miR-451a) that predicted the pathological response to neoadjuvant chemoradiotherapy were found to be associated with relapse-free survival other hsa-mir-451a "Adenocarcinoma, Esophageal" 29987600 Two miRNA ratios (miR-4521/miR-340-5p and miR-101-3p/miR-451a) that predicted the pathological response to neoadjuvant chemoradiotherapy were found to be associated with relapse-free survival other hsa-mir-4521 "Adenocarcinoma, Esophageal" 29987600 Two miRNA ratios (miR-4521/miR-340-5p and miR-101-3p/miR-451a) that predicted the pathological response to neoadjuvant chemoradiotherapy were found to be associated with relapse-free survival other hsa-let-7b Rectum Adenocarcinoma 29988972 we identified an association between increased let-7b and worse clinical outcomes other hsa-mir-152 "Carcinoma, Breast, Triple Negative" 29990486 Melatonin restrains angiogenic factors in triple-negative breast cancer by targeting miR-152-3p: In vivo and in vitro studies. other hsa-mir-155 Heart Failure 29990505 Osteoglycin post-transcriptional regulation by miR-155 induces cellular architecture changes in H9c2 cardiomyoblasts. other hsa-mir-21 "Carcinoma, Renal Cell" 29993250 Small Molecule Inhibition of MicroRNA miR-21 Rescues Chemosensitivity of Renal-Cell Carcinoma to Topotecan. other hsa-mir-146a Amyotrophic Lateral Sclerosis 29995256 Data indicate that astrocytes in mSOD1 mice model acquire early phenotypic aberrancies and highlight downregulated miR-146a as a biomarker and drug target in ALS other hsa-mir-149 Neoplasms [unspecific] 29999552 Regulation and functions of MicroRNA-149 in human cancers. other hsa-mir-30a Obesity 30002134 miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity. other hsa-mir-4455 Gastric Neoplasms 30002604 "Vasodilator-stimulated phosphoprotein (VASP), a novel target of miR-4455, promotes gastric cancer cell proliferation, migration, and invasion, through activating the PI3K/AKT signaling pathway." other hsa-mir-128 "Carcinoma, Breast" 30004628 TGF¦Â1 regulates HGF-induced cell migration and hepatocyte growth factor receptor MET expression via C-ets-1 and miR-128-3p in basal-like breast cancer. other hsa-mir-200a "Carcinoma, Thyroid, Papillary" 30005075 A potential biomarker hsa-miR-200a-5p distinguishing between benign thyroid tumors with papillary hyperplasia and papillary thyroid carcinoma. other hsa-mir-218 Amyotrophic Lateral Sclerosis 30007309 motor neuron-derived miR-218 may have a functional role in amyotrophic lateral sclerosis other hsa-mir-218 Prostate Neoplasms 30008871 "MicroRNA-218 inhibits the migration, epithelial-mesenchymal transition and cancer stem cell properties of prostate cancer cells." other hsa-mir-425 "Carcinoma, Renal Cell" 30008916 "Oncogenic miR-425-5p is associated with cellular migration, proliferation and apoptosis in renal cell carcinoma." other hsa-mir-23a Gastric Neoplasms 30008935 MicroRNA-23a/27a/24-2 cluster promotes gastric cancer cell proliferation synergistically. other hsa-mir-24-2 Gastric Neoplasms 30008935 MicroRNA-23a/27a/24-2 cluster promotes gastric cancer cell proliferation synergistically. other hsa-mir-27a Gastric Neoplasms 30008935 MicroRNA-23a/27a/24-2 cluster promotes gastric cancer cell proliferation synergistically. other hsa-mir-10a "Carcinoma, Breast" 30010434 "high expression of miR-134, miR-125b-5P, miRNA-30a, miR-10a-5p and miR-222 were significantly associated with short relapse-free time" other hsa-mir-125b "Carcinoma, Breast" 30010434 "high expression of miR-134, miR-125b-5P, miRNA-30a, miR-10a-5p and miR-222 were significantly associated with short relapse-free time" other hsa-mir-134 "Carcinoma, Breast" 30010434 "high expression of miR-134, miR-125b-5P, miRNA-30a, miR-10a-5p and miR-222 were significantly associated with short relapse-free time" other hsa-mir-222 "Carcinoma, Breast" 30010434 "high expression of miR-134, miR-125b-5P, miRNA-30a, miR-10a-5p and miR-222 were significantly associated with short relapse-free time" other hsa-mir-30a "Carcinoma, Breast" 30010434 "high expression of miR-134, miR-125b-5P, miRNA-30a, miR-10a-5p and miR-222 were significantly associated with short relapse-free time" other hsa-mir-146a Periodontitis 30012943 "These results suggest that CyP may modulate the pro-inflammatory response induced by Pg-LPS, not only by blocking TLR4-MD2 complex, but also by preserving miR-146a expression" other hsa-mir-9 Lung Neoplasms 30012957 Lamins in Lung Cancer: Biomarkers and Key Factors for Disease Progression through miR-9 Regulation other hsa-mir-127 Ovarian Neoplasms 30013629 miR-127 was negatively associated with tumor grade other hsa-mir-431 "Leukemia, Myeloid, Acute" 30013666 The transfection of miR-431 suppressed the migration and invasion of AML cells other hsa-mir-122 Ischemia-Reperfusion Injury 30014282 "The Effect of Zinc Sulfate on miR-122, miR-34a, Atioxidants, Biochemical and Histopathological Parameters Following Hepatic Ischemia/Reperfusion Injury in Rats." other hsa-mir-34a Ischemia-Reperfusion Injury 30014282 "The Effect of Zinc Sulfate on miR-122, miR-34a, Atioxidants, Biochemical and Histopathological Parameters Following Hepatic Ischemia/Reperfusion Injury in Rats." other hsa-mir-133b Peripheral Nerve Injury 30018017 Intrathecal Injection of miR-133b-3p or miR-143-3p Prevents the Development of Persistent Cold and Mechanical Allodynia Following a Peripheral Nerve Injury in Rats. other hsa-mir-143 Peripheral Nerve Injury 30018017 Intrathecal Injection of miR-133b-3p or miR-143-3p Prevents the Development of Persistent Cold and Mechanical Allodynia Following a Peripheral Nerve Injury in Rats. other hsa-let-7f Thyroid Neoplasms 30018229 "Treatment with selumetinib caused a down-regulation of hsa-let-7f-5p, hsa-miR-146b-5p and hsa-miR-146b-3p in TPC1 and BCPAP cells" other hsa-mir-146b Thyroid Neoplasms 30018229 "Treatment with selumetinib caused a down-regulation of hsa-let-7f-5p, hsa-miR-146b-5p and hsa-miR-146b-3p in TPC1 and BCPAP cells" other hsa-let-7 "Carcinoma, Breast" 30018709 "microRNAs (miR-21, miR-155-5p and let-7) may participate in the ILF2 expression network in breast cancer" other hsa-mir-155 "Carcinoma, Breast" 30018709 "microRNAs (miR-21, miR-155-5p and let-7) may participate in the ILF2 expression network in breast cancer" other hsa-mir-21 "Carcinoma, Breast" 30018709 "microRNAs (miR-21, miR-155-5p and let-7) may participate in the ILF2 expression network in breast cancer" other hsa-mir-4319 "Carcinoma, Breast, Triple Negative" 30021199 MiR-4319 Suppress the Malignancy of Triple-Negative Breast Cancer by Regulating Self-Renewal and Tumorigenesis of Stem Cells. other hsa-mir-21 "Carcinoma, Salivary Adenoid Cystic" 30021341 Effect of simvastatin and microRNA-21 inhibitor on metastasis and progression of human salivary adenoid cystic carcinoma. other hsa-mir-663a "Carcinoma, Renal Cell" 30021352 Oncogenic miR-663a is associated with cellular function and poor prognosis in renal cell carcinoma. other hsa-mir-34a Sepsis 30021364 MicroRNA-34a promotes iNOS secretion from pulmonary macrophages in septic suckling rats through activating STAT3 pathway. other hsa-mir-449a Osteoarthritis 30021388 MicroRNA-449a upregulation promotes chondrocyte extracellular matrix degradation in osteoarthritis. other hsa-mir-7 "Carcinoma, Lung, Non-Small-Cell" 30022841 Overexpressed CDR1as functions as an oncogene to promote the tumor progression via miR-7 in non-small-cell lung cancer. other hsa-mir-486 Lung Neoplasms 30023372 miR-486 inhibits PM2.5-induced apoptosis and oxidative stress in human lung alveolar epithelial A549 cells. other hsa-mir-218 Chronic Obstructive Pulmonary Disease 30024625 "miR-218-5p may, therefore, play an important role in the pathogenesis of COPD" other hsa-mir-137 Schizophrenia 30026708 Association of MIR137 With Symptom Severity and Cognitive Functioning in Belarusian Schizophrenia Patients. other hsa-mir-10b Neoplasms [unspecific] 30028875 Potent and selective effect of the mir-10b inhibitor MN-anti-mir10b in human cancer cells of diverse primary disease origin. other hsa-mir-1 Cardiac Myocyte Injury 30029588 "Six of them (miR-1, miR-208a-3p, miR-199a-5p, miR-21-5p, miR-146a-5p, and miR-30c-5p) were reported to be related to cardiac pathological functions" other hsa-mir-146a Cardiac Myocyte Injury 30029588 "Six of them (miR-1, miR-208a-3p, miR-199a-5p, miR-21-5p, miR-146a-5p, and miR-30c-5p) were reported to be related to cardiac pathological functions" other hsa-mir-199a Cardiac Myocyte Injury 30029588 "Six of them (miR-1, miR-208a-3p, miR-199a-5p, miR-21-5p, miR-146a-5p, and miR-30c-5p) were reported to be related to cardiac pathological functions" other hsa-mir-208a Cardiac Myocyte Injury 30029588 "Six of them (miR-1, miR-208a-3p, miR-199a-5p, miR-21-5p, miR-146a-5p, and miR-30c-5p) were reported to be related to cardiac pathological functions" other hsa-mir-21 Cardiac Myocyte Injury 30029588 "Six of them (miR-1, miR-208a-3p, miR-199a-5p, miR-21-5p, miR-146a-5p, and miR-30c-5p) were reported to be related to cardiac pathological functions" other hsa-mir-30c Cardiac Myocyte Injury 30029588 "Six of them (miR-1, miR-208a-3p, miR-199a-5p, miR-21-5p, miR-146a-5p, and miR-30c-5p) were reported to be related to cardiac pathological functions" other hsa-mir-124 Chronic Hepatitis B 30031388 "miRNA-15, miRNA-124, miRNA-218-5P with significant activation of Z-Score" other hsa-mir-15 Chronic Hepatitis B 30031388 "miRNA-15, miRNA-124, miRNA-218-5P with significant activation of Z-Score" other hsa-mir-218 Chronic Hepatitis B 30031388 "miRNA-15, miRNA-124, miRNA-218-5P with significant activation of Z-Score" other hsa-mir-374a "Carcinoma, Bladder" 30032142 MicroRNA-374a Inhibits Aggressive Tumor Biological Behavior in Bladder Carcinoma by Suppressing Wnt/¦Â-Catenin Signaling. other hsa-mir-16 Prostate Neoplasms 30032144 MiR-195/-16 Family Enhances Radiotherapy via T Cell Activation in the Tumor Microenvironment by Blocking the PD-L1 Immune Checkpoint. other hsa-mir-195 Prostate Neoplasms 30032144 MiR-195/-16 Family Enhances Radiotherapy via T Cell Activation in the Tumor Microenvironment by Blocking the PD-L1 Immune Checkpoint. other hsa-mir-141 Glioma 30034253 The miR-200 family: multiple effects on gliomas. other hsa-mir-200a Glioma 30034253 The miR-200 family: multiple effects on gliomas. other hsa-mir-200b Glioma 30034253 The miR-200 family: multiple effects on gliomas. other hsa-mir-200c Glioma 30034253 The miR-200 family: multiple effects on gliomas. other hsa-mir-429 Glioma 30034253 The miR-200 family: multiple effects on gliomas. other hsa-mir-494 Spinal Cord Injuries 30036869 Effects of MicroRNA-494 on Astrocyte Proliferation and Synaptic Remodeling in the Spinal Cord of a Rat Model of Chronic Compressive Spinal Cord Injury by Regulating the Nogo/Ngr Signaling Pathway. other hsa-mir-363 Ovarian Neoplasms 30037365 MiR-363 inhibits cisplatin chemoresistance of epithelial ovarian cancer by regulating snail-induced epithelial-mesenchymal transition. other hsa-mir-17 "Lymphoma, Non-Hodgkin" 30038718 "Lymphomas clustered according to histological subtypes, driven by two miRNA clusters (the miR-29 family and the miR-17-92 cluster)" other hsa-mir-18 "Lymphoma, Non-Hodgkin" 30038718 "Lymphomas clustered according to histological subtypes, driven by two miRNA clusters (the miR-29 family and the miR-17-92 cluster)" other hsa-mir-19a "Lymphoma, Non-Hodgkin" 30038718 "Lymphomas clustered according to histological subtypes, driven by two miRNA clusters (the miR-29 family and the miR-17-92 cluster)" other hsa-mir-19b-1 "Lymphoma, Non-Hodgkin" 30038718 "Lymphomas clustered according to histological subtypes, driven by two miRNA clusters (the miR-29 family and the miR-17-92 cluster)" other hsa-mir-20a "Lymphoma, Non-Hodgkin" 30038718 "Lymphomas clustered according to histological subtypes, driven by two miRNA clusters (the miR-29 family and the miR-17-92 cluster)" other hsa-mir-29a "Lymphoma, Non-Hodgkin" 30038718 "Lymphomas clustered according to histological subtypes, driven by two miRNA clusters (the miR-29 family and the miR-17-92 cluster)" other hsa-mir-29b "Lymphoma, Non-Hodgkin" 30038718 "Lymphomas clustered according to histological subtypes, driven by two miRNA clusters (the miR-29 family and the miR-17-92 cluster)" other hsa-mir-29c "Lymphoma, Non-Hodgkin" 30038718 "Lymphomas clustered according to histological subtypes, driven by two miRNA clusters (the miR-29 family and the miR-17-92 cluster)" other hsa-mir-92-1 "Lymphoma, Non-Hodgkin" 30038718 "Lymphomas clustered according to histological subtypes, driven by two miRNA clusters (the miR-29 family and the miR-17-92 cluster)" other hsa-mir-29c "Carcinoma, Renal Cell, Clear-Cell" 30041179 Upregulation of MIAT Regulates LOXL2 Expression by Competitively Binding MiR-29c in Clear Cell Renal Cell Carcinoma. other hsa-mir-134 Parkinson Disease 30041414 Delivery of miRNA-Targeted Oligonucleotides in the Rat Striatum by Magnetofection with Neuromag?. other hsa-mir-141 "Adenocarcinoma, Pancreatic Ductal" 30041660 WIPF1 antagonizes the tumor suppressive effect of miR-141/200c and is associated with poor survival in patients with PDAC. other hsa-mir-200c "Adenocarcinoma, Pancreatic Ductal" 30041660 WIPF1 antagonizes the tumor suppressive effect of miR-141/200c and is associated with poor survival in patients with PDAC. other hsa-mir-135a Lung Injury [unspecific] 30045018 MiR-135a Protects Vascular Endothelial Cells Against Ventilator-Induced Lung Injury by Inhibiting PHLPP2 to Activate PI3K/Akt Pathway. other hsa-mir-21 Rheumatoid Arthritis 30045854 Maresin 1 improves the Treg/Th17 imbalance in rheumatoid arthritis through miR-21. other hsa-mir-132 Inflammatory Bowel Diseases 30046303 "Regarding autophagy-related pathways, miR-146b, miR-221-5p, miR-132, miR-223, miR-155, and miR-21 regulate NF-¦ÊB or mTOR signaling to induce or inhibit autophagy in intestinal cells by releasing anti- or proinflammatory factors, respectively" other hsa-mir-146b Inflammatory Bowel Diseases 30046303 "Regarding autophagy-related pathways, miR-146b, miR-221-5p, miR-132, miR-223, miR-155, and miR-21 regulate NF-¦ÊB or mTOR signaling to induce or inhibit autophagy in intestinal cells by releasing anti- or proinflammatory factors, respectively" other hsa-mir-155 Inflammatory Bowel Diseases 30046303 "Regarding autophagy-related pathways, miR-146b, miR-221-5p, miR-132, miR-223, miR-155, and miR-21 regulate NF-¦ÊB or mTOR signaling to induce or inhibit autophagy in intestinal cells by releasing anti- or proinflammatory factors, respectively" other hsa-mir-21 Inflammatory Bowel Diseases 30046303 "Regarding autophagy-related pathways, miR-146b, miR-221-5p, miR-132, miR-223, miR-155, and miR-21 regulate NF-¦ÊB or mTOR signaling to induce or inhibit autophagy in intestinal cells by releasing anti- or proinflammatory factors, respectively" other hsa-mir-221 Inflammatory Bowel Diseases 30046303 "Regarding autophagy-related pathways, miR-146b, miR-221-5p, miR-132, miR-223, miR-155, and miR-21 regulate NF-¦ÊB or mTOR signaling to induce or inhibit autophagy in intestinal cells by releasing anti- or proinflammatory factors, respectively" other hsa-mir-223 Inflammatory Bowel Diseases 30046303 "Regarding autophagy-related pathways, miR-146b, miR-221-5p, miR-132, miR-223, miR-155, and miR-21 regulate NF-¦ÊB or mTOR signaling to induce or inhibit autophagy in intestinal cells by releasing anti- or proinflammatory factors, respectively" other hsa-mir-15a Neoplasms [unspecific] 30047999 miR-15a/16 deletion in macrophages holds a distinct biological significance from that of the microRNA deficiency in tumour cells other hsa-mir-16 Neoplasms [unspecific] 30047999 miR-15a/16 deletion in macrophages holds a distinct biological significance from that of the microRNA deficiency in tumour cells other hsa-mir-101 Neoplasms [unspecific] 30049386 A Nucleolar Stress-Specific p53-miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network. other hsa-mir-214 Hypertension 30049682 MicroRNA-214-3p in the Kidney Contributes to the Development of Hypertension. other hsa-mir-26b Colorectal Carcinoma 30051451 miR-26b may promote the invasion and metastasis of colorectal cancer by accelerating the migration and invasion of colorectal cancer cells other hsa-mir-190b "Carcinoma, Breast" 30055304 "Tree-based machine learning modelstrained in my analysis used hsa-miR-139 with hsa-miR-183 to classify breast tumors from normal samples, and hsa-miR4728 with hsa-miR190b to further classify these tumors into three major subtypes of breast cancer" other hsa-mir-4728 "Carcinoma, Breast" 30055304 "Tree-based machine learning modelstrained in my analysis used hsa-miR-139 with hsa-miR-183 to classify breast tumors from normal samples, and hsa-miR4728 with hsa-miR190b to further classify these tumors into three major subtypes of breast cancer" other hsa-mir-146a Colon Neoplasms 30056535 Fascin protein stabilization by miR-146a implicated in the process of a chronic inflammation-related colon carcinogenesis model. other hsa-mir-122 Hepatitis C Virus Infection 30058773 Hepatitis C Virus Infection of Cultured Cells and Primary Human Hepatocytes. other hsa-mir-145 Bicuspid Aortic Valve Disease 30059548 MiR-145 expression and rare NOTCH1 variants in bicuspid aortic valve-associated aortopathy. other hsa-mir-192 Hepatitis B Virus Infection 30059664 HBV upregulates the expression of miR-192-5p and miR-194-5p in the host cell other hsa-mir-194 Hepatitis B Virus Infection 30059664 HBV upregulates the expression of miR-192-5p and miR-194-5p in the host cell other hsa-mir-218 Preeclampsia 30061037 MicroRNA-218-5p Promotes Endovascular Trophoblast Differentiation and Spiral Artery Remodeling. other hsa-mir-205 "Carcinoma, Renal Cell, Clear-Cell" 30061948 Comparison of exosomal microRNAs secreted by 786-O clear cell renal carcinoma cells and HK-2 proximal tubule-derived cells in culture identifies microRNA-205 as a potential biomarker of clear cell renal carcinoma. other hsa-mir-786 "Carcinoma, Renal Cell, Clear-Cell" 30061948 Comparison of exosomal microRNAs secreted by 786-O clear cell renal carcinoma cells and HK-2 proximal tubule-derived cells in culture identifies microRNA-205 as a potential biomarker of clear cell renal carcinoma. other hsa-mir-331 "Carcinoma, Breast" 30063890 A comprehensive clinicopathological evaluation of the differential expression of microRNA-331 in breast tumors and its diagnostic significance. other hsa-mir-21 Traumatic Brain Injury 30066160 MicroRNA-21 in the Pathogenesis of Traumatic Brain Injury. other hsa-mir-142 "Leukemia, Lymphoblastic, Acute" 30066657 "We successfully identified two microRNAs, hsa-miR-142-3p and hsa-miR-17-5p, which are computationally predicted to closely relate to glucocorticoid resistance" other hsa-mir-17 "Leukemia, Lymphoblastic, Acute" 30066657 "We successfully identified two microRNAs, hsa-miR-142-3p and hsa-miR-17-5p, which are computationally predicted to closely relate to glucocorticoid resistance" other hsa-mir-205 Prostate Neoplasms 30066866 Ultrasound?targeted microbubble destruction?mediated miR?205 enhances cisplatin cytotoxicity in prostate cancer cells. other hsa-mir-320a Neoplasms [unspecific] 30066913 "Transcriptional activation of miR-320a by ATF2, ELK1 and YY1 induces cancer cell apoptosis under ionizing radiation conditions." other hsa-mir-124 Gastric Neoplasms 30068360 The targets of circHIPK3-miR-124/miR-29b axes involved in the progression of GC other hsa-mir-29b Gastric Neoplasms 30068360 The targets of circHIPK3-miR-124/miR-29b axes involved in the progression of GC other hsa-mir-146a Osteoarthritis 30071609 the reduced expression of miR-146a was found to be coupled to reduced type II collagen (COL2) in OA cartilage other hsa-mir-24 Mesothelioma 30072395 A Polysome-Based microRNA Screen Identifies miR-24-3p as a Novel Promigratory miRNA in Mesothelioma. other hsa-mir-146b Vascular Disease [unspecific] 30073586 Loss of miR-146b-3p Inhibits Perivascular Adipocyte Browning with Cold Exposure During Aging. other hsa-mir-302b "Carcinoma, Bladder" 30075175 MiR-302b regulates cell functions and acts as a potential biomarker to predict recurrence in bladder cancer. other hsa-mir-17 Leukemia 30076175 Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells. other hsa-mir-18 Leukemia 30076175 Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells. other hsa-mir-19a Leukemia 30076175 Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells. other hsa-mir-19b-1 Leukemia 30076175 Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells. other hsa-mir-20a Leukemia 30076175 Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells. other hsa-mir-92-1 Leukemia 30076175 Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells. other hsa-mir-214 Muscle Diseases [unspecific] 30076721 MiR-214 is an important regulator of the musculoskeletal metabolism and disease. other hsa-mir-142 Colitis 30076847 "administration of tetracyclines led to increased mucosal protection, associated with up-regulated expression of CCL2, miR-142 and miR-375" other hsa-mir-375 Colitis 30076847 "administration of tetracyclines led to increased mucosal protection, associated with up-regulated expression of CCL2, miR-142 and miR-375" other hsa-mir-548 Subacute Sclerosing Panencephalitis 30077763 "IL28B, IL29 and micro-RNA 548 in subacute sclerosing panencephalitis as a rare disease." other hsa-mir-195 Preeclampsia 30078346 Regulatory effect of miR-195 in the placental dysfunction of preeclampsia. other hsa-mir-142 Rheumatoid Arthritis 30081592 "Experimental and bioinformatics analyses revealed 8 miRNAs (miR-22, miR-27a, miR-96, miR-142, miR-223, miR-296, miR-298, and miR-451) and their target genes in functional pathways important for RA pathogenesis" other hsa-mir-22 Rheumatoid Arthritis 30081592 "Experimental and bioinformatics analyses revealed 8 miRNAs (miR-22, miR-27a, miR-96, miR-142, miR-223, miR-296, miR-298, and miR-451) and their target genes in functional pathways important for RA pathogenesis" other hsa-mir-223 Rheumatoid Arthritis 30081592 "Experimental and bioinformatics analyses revealed 8 miRNAs (miR-22, miR-27a, miR-96, miR-142, miR-223, miR-296, miR-298, and miR-451) and their target genes in functional pathways important for RA pathogenesis" other hsa-mir-27a Rheumatoid Arthritis 30081592 "Experimental and bioinformatics analyses revealed 8 miRNAs (miR-22, miR-27a, miR-96, miR-142, miR-223, miR-296, miR-298, and miR-451) and their target genes in functional pathways important for RA pathogenesis" other hsa-mir-296 Rheumatoid Arthritis 30081592 "Experimental and bioinformatics analyses revealed 8 miRNAs (miR-22, miR-27a, miR-96, miR-142, miR-223, miR-296, miR-298, and miR-451) and their target genes in functional pathways important for RA pathogenesis" other hsa-mir-298 Rheumatoid Arthritis 30081592 "Experimental and bioinformatics analyses revealed 8 miRNAs (miR-22, miR-27a, miR-96, miR-142, miR-223, miR-296, miR-298, and miR-451) and their target genes in functional pathways important for RA pathogenesis" other hsa-mir-451 Rheumatoid Arthritis 30081592 "Experimental and bioinformatics analyses revealed 8 miRNAs (miR-22, miR-27a, miR-96, miR-142, miR-223, miR-296, miR-298, and miR-451) and their target genes in functional pathways important for RA pathogenesis" other hsa-mir-96 Rheumatoid Arthritis 30081592 "Experimental and bioinformatics analyses revealed 8 miRNAs (miR-22, miR-27a, miR-96, miR-142, miR-223, miR-296, miR-298, and miR-451) and their target genes in functional pathways important for RA pathogenesis" other hsa-mir-145 "Adenocarcinoma, Lung" 30082847 Dual strands of the miR-145 duplex (miR-145-5p and miR-145-3p) regulate oncogenes in lung adenocarcinoma pathogenesis. other hsa-mir-388 Pemphigus 30083474 Usefulness of miRNA-338-3p in the diagnosis of pemphigus and its correlation with disease severity. other hsa-mir-144 Myocardial Infarction 30084039 Intravenous miR-144 reduces left ventricular remodeling after myocardial infarction. other hsa-mir-199a "Carcinoma, Breast, Triple Negative" 30086965 "Design, development and evaluation of microRNA-199a-5p detecting electrochemical nanobiosensor with diagnostic application in Triple Negative Breast Cancer." other hsa-mir-373 Hepatitis C Virus Infection 30089699 Association between MicroRNA-373 and Long Noncoding RNA NORAD in Hepatitis C Virus-Infected Hepatocytes Impairs Wee1 Expression for Growth Promotion. other hsa-mir-17 Intervertebral Disc Degeneration 30089772 whereas circRNA_104670 and miRNA-17-3p inhibition mice had a higher IDD grade compared with circRNA_104670 inhibition mice other hsa-mir-203 "Carcinoma, Breast" 30091053 Lack of effective translational regulation of PLD expression and exosome biogenesis in triple-negative breast cancer cells. other hsa-mir-142 "Carcinoma, Breast" 30091683 miR-142-3p attenuates breast cancer stem cell characteristics and decreases radioresistance in vitro. other hsa-mir-17 Liver Diseases [unspecific] 30092337 Bone marrow mesenchymal stromal cells attenuate liver allograft rejection may via upregulation PD-L1 expression through downregulation of miR-17-5p. other hsa-mir-15a Premature Ovarian Failure 30092342 Induction of miR-15a expression by tripterygium glycosides caused premature ovarian failure by suppressing the Hippo-YAP/TAZ signaling effector Lats1. other hsa-mir-1 Viral Myocarditis 30097120 Astragalus Root dry extract restores connexin43 expression by targeting miR-1 in viral myocarditis. other hsa-mir-885 "Carcinoma, Salivary Adenoid Cystic" 30098429 Comprehensive and in-depth analysis of microRNA and mRNA expression profile in salivary adenoid cystic carcinoma. other hsa-mir-9 Myocardial Infarction 30101604 Inhibition of MicroRNA-9-5p Protects Against Cardiac Remodeling Following Myocardial Infarction in Mice. other hsa-mir-324 Colorectal Carcinoma 30103475 4-Acetyl-Antroquinonol B Suppresses SOD2-Enhanced Cancer Stem Cell-Like Phenotypes and Chemoresistance of Colorectal Cancer Cells by Inducing hsa-miR-324 re-Expression. other hsa-mir-675 "Squamous Cell Carcinoma, Esophageal" 30106155 MicroRNA?675?3p promotes esophageal squamous cell cancer cell migration and invasion. other hsa-mir-221 Parkinson Disease 30107296 The Parkinson's disease gene product DJ-1 modulates miR-221 to promote neuronal survival against oxidative stress. other hsa-mir-449a "Carcinoma, Hepatocellular" 30108016 MicroRNA-449a suppresses hepatocellular carcinoma cell growth via G1 phase arrest and the HGF/MET c-Met pathway. other hsa-mir-144 Lung Neoplasms 30108506 Lico A Causes ER Stress and Apoptosis via Up-Regulating miR-144-3p in Human Lung Cancer Cell Line H292. other hsa-mir-15a Neoplasms [unspecific] 30110127 "TEC treated with HLSC-EVs significantly enhanced expression of miR-15a, miR-181b, miR-320c and miR-874 associated with the down-regulation of FGF1 and PLAU" other hsa-mir-181b Neoplasms [unspecific] 30110127 "TEC treated with HLSC-EVs significantly enhanced expression of miR-15a, miR-181b, miR-320c and miR-874 associated with the down-regulation of FGF1 and PLAU" other hsa-mir-320c Neoplasms [unspecific] 30110127 "TEC treated with HLSC-EVs significantly enhanced expression of miR-15a, miR-181b, miR-320c and miR-874 associated with the down-regulation of FGF1 and PLAU" other hsa-mir-874 Neoplasms [unspecific] 30110127 "TEC treated with HLSC-EVs significantly enhanced expression of miR-15a, miR-181b, miR-320c and miR-874 associated with the down-regulation of FGF1 and PLAU" other hsa-mir-199a Autism Spectrum Disorder 30111726 Alterations in the MicroRNA of the Blood of Autism Spectrum Disorder Patients: Effects on Epigenetic Regulation and Potential Biomarkers. other hsa-mir-16 Gastric Neoplasms 30112563 "The miR-16-5p, which has binding sites with hsa_circ_0008106 and hsa_circ_0060456, has been confirmed to be involved in the development of gastric cancer" other hsa-mir-21 Neoplasms [unspecific] 30113161 we used an alternative target (miR-21) and FRET pair for direct and absolute quantification of miR-21 in RNA extracts from human cancer and normal cell lines other hsa-mir-199a Hypertension 30116316 MicroRNA-199a-5p aggravates primary hypertension by damaging vascular endothelial cells through inhibition of autophagy and promotion of apoptosis. other hsa-mir-1826 "Carcinoma, Hepatocellular" 30116730 "we identified 7 DV-only miRNAs (hsa-miR-1826, hsa-miR-191, hsa-miR-194-star, hsa-miR-222, hsa-miR-502-3p, hsa-miR-93, and hsa-miR-99b) using the proposed method, one (hsa-miR-1826) of which has not yet been reported to be related to HCC in the literature" other hsa-mir-191 "Carcinoma, Hepatocellular" 30116730 "we identified 7 DV-only miRNAs (hsa-miR-1826, hsa-miR-191, hsa-miR-194-star, hsa-miR-222, hsa-miR-502-3p, hsa-miR-93, and hsa-miR-99b) using the proposed method, one (hsa-miR-1826) of which has not yet been reported to be related to HCC in the literature" other hsa-mir-194 "Carcinoma, Hepatocellular" 30116730 "we identified 7 DV-only miRNAs (hsa-miR-1826, hsa-miR-191, hsa-miR-194-star, hsa-miR-222, hsa-miR-502-3p, hsa-miR-93, and hsa-miR-99b) using the proposed method, one (hsa-miR-1826) of which has not yet been reported to be related to HCC in the literature" other hsa-mir-222 "Carcinoma, Hepatocellular" 30116730 "we identified 7 DV-only miRNAs (hsa-miR-1826, hsa-miR-191, hsa-miR-194-star, hsa-miR-222, hsa-miR-502-3p, hsa-miR-93, and hsa-miR-99b) using the proposed method, one (hsa-miR-1826) of which has not yet been reported to be related to HCC in the literature" other hsa-mir-502 "Carcinoma, Hepatocellular" 30116730 "we identified 7 DV-only miRNAs (hsa-miR-1826, hsa-miR-191, hsa-miR-194-star, hsa-miR-222, hsa-miR-502-3p, hsa-miR-93, and hsa-miR-99b) using the proposed method, one (hsa-miR-1826) of which has not yet been reported to be related to HCC in the literature" other hsa-mir-93 "Carcinoma, Hepatocellular" 30116730 "we identified 7 DV-only miRNAs (hsa-miR-1826, hsa-miR-191, hsa-miR-194-star, hsa-miR-222, hsa-miR-502-3p, hsa-miR-93, and hsa-miR-99b) using the proposed method, one (hsa-miR-1826) of which has not yet been reported to be related to HCC in the literature" other hsa-mir-99b "Carcinoma, Hepatocellular" 30116730 "we identified 7 DV-only miRNAs (hsa-miR-1826, hsa-miR-191, hsa-miR-194-star, hsa-miR-222, hsa-miR-502-3p, hsa-miR-93, and hsa-miR-99b) using the proposed method, one (hsa-miR-1826) of which has not yet been reported to be related to HCC in the literature" other hsa-mir-21 Osteoporosis 30116953 The pivotal role of microRNA-21 in osteoclastogenesis inhibition by anthracycline glycoside aloin. other hsa-mir-1 Heart Failure 30117672 Lycium barbarum polysaccharides restore adverse structural remodelling and cardiac contractile dysfunction induced by overexpression of microRNA-1. other hsa-mir-92a Wound Healing 30118158 A synthetic microRNA-92a inhibitor (MRG-110) accelerates angiogenesis and wound healing in diabetic and nondiabetic wounds. other hsa-mir-192 Mild Cognitive Impairment 30118321 Up-regulated miR-192-5p expression rescues cognitive impairment and restores neural function in mice with depression via the Fbln2-mediated TGF-¦Â1 signaling pathway. other hsa-mir-144 "Adenocarcinoma, Lung" 30121641 IL-1¦Â-Mediated Up-Regulation of WT1D via miR-144-3p and Their Synergistic Effect with NF-¦ÊB/COX-2/HIF-1¦Á Pathway on Cell Proliferation in LUAD. other hsa-mir-26b Glioma 30124166 the TFAP2C and hsa-miR-26b-5p might play important roles in the development and progression mechanisms of DIPG other hsa-mir-146a Lichen Planus 30125971 Forkhead box p3 controls progression of oral lichen planus by regulating microRNA-146a. other hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 30127862 MicroRNA-21: A promising biomarker for the prognosis and diagnosis of non-small cell lung cancer. other hsa-mir-182 Amyotrophic Lateral Sclerosis 30128653 Memory Decline and Its Reversal in Aging and Neurodegeneration Involve miR-183/96/182 Biogenesis. other hsa-mir-183 Amyotrophic Lateral Sclerosis 30128653 Memory Decline and Its Reversal in Aging and Neurodegeneration Involve miR-183/96/182 Biogenesis. other hsa-mir-96 Amyotrophic Lateral Sclerosis 30128653 Memory Decline and Its Reversal in Aging and Neurodegeneration Involve miR-183/96/182 Biogenesis. other hsa-mir-31 Cutaneous Lupus Erythematosus 30130620 MicroRNA Expression Profiling Identifies miR-31 and miR-485-3p as Regulators in the Pathogenesis of Discoid Cutaneous Lupus. other hsa-mir-485 Cutaneous Lupus Erythematosus 30130620 MicroRNA Expression Profiling Identifies miR-31 and miR-485-3p as Regulators in the Pathogenesis of Discoid Cutaneous Lupus. other hsa-mir-299 "Diabetes Mellitus, Type 2" 30131392 Glucolipotoxicity-Inhibited miR-299-5p Regulates Pancreatic ¦Â-Cell Function and Survival. other hsa-mir-181 Chronic Kidney Disease 30132347 Electrically stimulated acupuncture increases renal blood flow through exosomes-carried miR-181. other hsa-mir-132 "Carcinoma, Cervical" 30132864 HPV16 E7-induced upregulation of KDM2A promotes cervical cancer progression by regulating miR-132-radixin pathway. other hsa-mir-199 Hepatitis C Virus Infection 30133717 "miR-23b and miR-106 might be a useful biomarker for chronic hepatitis C (CHC). MiR-27a, miR-93, and miR-199 might have a potential role in the progression of liver diseases" other hsa-mir-27a Hepatitis C Virus Infection 30133717 "miR-23b and miR-106 might be a useful biomarker for chronic hepatitis C (CHC). MiR-27a, miR-93, and miR-199 might have a potential role in the progression of liver diseases" other hsa-mir-93 Hepatitis C Virus Infection 30133717 "miR-23b and miR-106 might be a useful biomarker for chronic hepatitis C (CHC). MiR-27a, miR-93, and miR-199 might have a potential role in the progression of liver diseases" other hsa-mir-145 Prostate Neoplasms 30136305 MiR-145 affected the circular RNA expression in prostate cancer LNCaP cells. other hsa-mir-92a Acute Lung Injury 30138892 MicroRNA-92a antagonism attenuates lipopolysaccharide (LPS)-induced pulmonary inflammation and injury in mice through suppressing the PTEN/AKT/NF-¦ÊB signaling pathway. other hsa-mir-195 Wound Healing 30141361 Negative-Pressure Wound Therapy Promotes Wound Healing by Enhancing Angiogenesis Through Suppression of NLRX1 via miR-195 Upregulation. other hsa-mir-1908 Autoimmune Diseases [unspecific] 30143393 Evidence for a potential role of miR-1908-5p and miR-3614-5p in autoimmune disease risk using integrative bioinformatics. other hsa-mir-3614 Autoimmune Diseases [unspecific] 30143393 Evidence for a potential role of miR-1908-5p and miR-3614-5p in autoimmune disease risk using integrative bioinformatics. other hsa-mir-200a Hypertrophy 30144391 miR-200a-5p augments cardiomyocyte hypertrophy induced by glucose metabolism disorder via the regulation of selenoproteins. other hsa-mir-205 Prostate Neoplasms 30149628 miRNA-205 Nanoformulation Sensitizes Prostate Cancer Cells to Chemotherapy. other hsa-mir-375 "Diabetes Mellitus, Type 1" 30150203 Several types of miRNAs are playing important roles in type 1 diabetes mellitus including miR-375 and miR-375 with intolerance to glucose and decreased beta cells account due to impaired proliferation other hsa-mir-320a Chronic Pain 30150364 A Functional riboSNitch in the 3' Untranslated Region of FKBP5 Alters MicroRNA-320a Binding Efficiency and Mediates Vulnerability to Chronic Post-Traumatic Pain. other hsa-mir-155 Melanoma 30150674 Inhibition of miR-155 and miR-210 activity by transfection of miRNA inhibitors into HMEX reversed the exosome-induced metabolic reprogramming of HADF other hsa-mir-210 Melanoma 30150674 Inhibition of miR-155 and miR-210 activity by transfection of miRNA inhibitors into HMEX reversed the exosome-induced metabolic reprogramming of HADF other hsa-mir-139 "Carcinoma, Lung, Non-Small-Cell" 30153566 BMP4?Upregulation Is Associated with Acquired Drug Resistance and Fatty Acid Metabolism in EGFR-Mutant Non-Small-Cell Lung Cancer Cells. other hsa-mir-16 "Carcinoma, Breast" 30154547 "Different signatures of miR-16, miR-30b and miR-93 in exosomes from breast cancer and DCIS patients." other hsa-mir-30b "Carcinoma, Breast" 30154547 "Different signatures of miR-16, miR-30b and miR-93 in exosomes from breast cancer and DCIS patients." other hsa-mir-93 "Carcinoma, Breast" 30154547 "Different signatures of miR-16, miR-30b and miR-93 in exosomes from breast cancer and DCIS patients." other hsa-mir-124 Bone Disease [unspecific] 30155647 miR-124-3p is a chronic regulator of gene expression after brain injury. other hsa-mir-570 Chronic Obstructive Pulmonary Disease 30156909 MicroRNA-570 is a novel regulator of cellular senescence and inflammaging. other hsa-mir-214 Colorectal Carcinoma 30157478 Down-Regulation of MicroRNA-214 Contributed to the Enhanced Mitochondrial Transcription Factor A and Inhibited Proliferation of Colorectal Cancer Cells. other hsa-mir-410 Lung Fibrosis 30157485 Prodigiosin Alleviates Pulmonary Fibrosis Through Inhibiting miRNA-410 and TGF-¦Â1/ADAMTS-1 Signaling Pathway. other hsa-mir-218 Rheumatoid Arthritis 30157923 Osteogenic differentiation of fibroblast-like synovial cells in rheumatoid arthritis is induced by microRNA-218 through a ROBO/Slit pathway. other hsa-mir-182 "Diabetes Mellitus, Type 2" 30160993 Intestinal bile acid sequestration improves glucose control by stimulating hepatic miR-182-5p in type 2 diabetes. other hsa-mir-10b Neoplasms [unspecific] 30166612 "we further propose that miR-10b expression levels, due to the newly described ""hijacking"" effect, may be used as a biomarker to select patients for linifanib treatment" other hsa-mir-187 Retinal Vascular Disease 30170060 Down-regulated miR-187 promotes oxidative stress-induced retinal cell apoptosis through P2X7 receptor. other hsa-mir-17 Gastric Neoplasms 30170406 miR-17-92 cluster is connected with disease progression and oxaliplatin/capecitabine chemotherapy efficacy in advanced gastric cancer patients: A preliminary study. other hsa-mir-18 Gastric Neoplasms 30170406 miR-17-92 cluster is connected with disease progression and oxaliplatin/capecitabine chemotherapy efficacy in advanced gastric cancer patients: A preliminary study. other hsa-mir-19a Gastric Neoplasms 30170406 miR-17-92 cluster is connected with disease progression and oxaliplatin/capecitabine chemotherapy efficacy in advanced gastric cancer patients: A preliminary study. other hsa-mir-19b-1 Gastric Neoplasms 30170406 miR-17-92 cluster is connected with disease progression and oxaliplatin/capecitabine chemotherapy efficacy in advanced gastric cancer patients: A preliminary study. other hsa-mir-20a Gastric Neoplasms 30170406 miR-17-92 cluster is connected with disease progression and oxaliplatin/capecitabine chemotherapy efficacy in advanced gastric cancer patients: A preliminary study. other hsa-mir-92-1 Gastric Neoplasms 30170406 miR-17-92 cluster is connected with disease progression and oxaliplatin/capecitabine chemotherapy efficacy in advanced gastric cancer patients: A preliminary study. other hsa-mir-372 Colorectal Carcinoma 30171794 miR-372 and miR-373 enhance the stemness of colorectal cancer cells by repressing differentiation signaling pathways. other hsa-mir-373 Colorectal Carcinoma 30171794 miR-372 and miR-373 enhance the stemness of colorectal cancer cells by repressing differentiation signaling pathways. other hsa-mir-30c-2 "Carcinoma, Breast" 30182731 Circular RNA hsa_circ_0072995 promotes breast cancer cell migration and invasion through sponge for miR-30c-2-3p. other hsa-mir-497 "Carcinoma, Renal Cell, Clear-Cell" 30183478 MicroRNA-497-5p down-regulation increases PD-L1 expression in clear cell renal cell carcinoma. other hsa-mir-27a Gastric Neoplasms 30184548 Exosomal miR-27a Derived from Gastric Cancer Cells Regulates the Transformation of Fibroblasts into Cancer-Associated Fibroblasts. other hsa-mir-3607 "Carcinoma, Hepatocellular" 30186744 "mir-424, miR-93 and miR-3607 are three hub DEmiRNAs of the HCC-specific DEmiRNA-DEmRNA interaction network." other hsa-mir-424 "Carcinoma, Hepatocellular" 30186744 "mir-424, miR-93 and miR-3607 are three hub DEmiRNAs of the HCC-specific DEmiRNA-DEmRNA interaction network." other hsa-mir-93 "Carcinoma, Hepatocellular" 30186744 "mir-424, miR-93 and miR-3607 are three hub DEmiRNAs of the HCC-specific DEmiRNA-DEmRNA interaction network." other hsa-mir-17 Gastric Neoplasms 30186751 "MicroRNA-17 as a promising diagnostic biomarker of gastric cancer: An investigation combining TCGA, GEO, meta-analysis, and bioinformatics." other hsa-mir-106b Recurrent Spontaneous Abortion 30187472 Altered T-cell subpopulations in recurrent pregnancy loss patients with cellular immune abnormalities. other hsa-mir-25 Recurrent Spontaneous Abortion 30187472 Altered T-cell subpopulations in recurrent pregnancy loss patients with cellular immune abnormalities. other hsa-mir-93 Recurrent Spontaneous Abortion 30187472 Altered T-cell subpopulations in recurrent pregnancy loss patients with cellular immune abnormalities. other hsa-mir-520a Hepatitis B Virus Infection 30191752 MicroRNA-520a suppresses HBV replication in HepG2.2.15 cells by inactivating AKT. other hsa-mir-21 Colorectal Carcinoma 30191984 Fusobacterium nucleatum and colorectal cancer: A mechanistic overview. other hsa-mir-199a Coronary Artery Disease 30192743 MicroRNA 199a Is Downregulated in Patients After Coronary Artery Bypass Graft Surgery and Is Associated with Increased Levels of Sirtuin 1 (SIRT 1) Protein and Major Adverse Cardiovascular Events at 3-Year Follow-Up. other hsa-mir-215 "Carcinoma, Breast" 30194145 Pax-5 Inhibits Breast Cancer Proliferation Through MiR-215 Up-regulation. other hsa-mir-17 Prostate Neoplasms 30194146 "we identified a panel of 5-miRNA (miR-17-3p, miR-27a-3p, miR-200a-3p, miR-375, and miR-376b-3p) with a risk score strongly associated with metastasis" other hsa-mir-200a Prostate Neoplasms 30194146 "we identified a panel of 5-miRNA (miR-17-3p, miR-27a-3p, miR-200a-3p, miR-375, and miR-376b-3p) with a risk score strongly associated with metastasis" other hsa-mir-27a Prostate Neoplasms 30194146 "we identified a panel of 5-miRNA (miR-17-3p, miR-27a-3p, miR-200a-3p, miR-375, and miR-376b-3p) with a risk score strongly associated with metastasis" other hsa-mir-375 Prostate Neoplasms 30194146 "we identified a panel of 5-miRNA (miR-17-3p, miR-27a-3p, miR-200a-3p, miR-375, and miR-376b-3p) with a risk score strongly associated with metastasis" other hsa-mir-376b Prostate Neoplasms 30194146 "we identified a panel of 5-miRNA (miR-17-3p, miR-27a-3p, miR-200a-3p, miR-375, and miR-376b-3p) with a risk score strongly associated with metastasis" other hsa-mir-155 "Squamous Cell Carcinoma, Oral" 30194167 Potential Oncogenic Role and Prognostic Implication of MicroRNA-155-5p in Oral Squamous Cell Carcinoma. other hsa-mir-96 "Adenocarcinoma, Prostate" 30195637 "The lncRNAs MESTIT1, PCA3, and UCA1; mRNAs CYP19A1 and TDRD1; as well as miR-96 might affect the pathogenesis of PRAD" other hsa-mir-1271 Colorectal Carcinoma 30195762 "sequester miR-135a, miR-143, miR-214, and miR-1271, protecting ANLN, BIRC5, IPO7, KIF2A, and KIF23 from microRNA (miRNA)-induced degradation" other hsa-mir-135a Colorectal Carcinoma 30195762 "sequester miR-135a, miR-143, miR-214, and miR-1271, protecting ANLN, BIRC5, IPO7, KIF2A, and KIF23 from microRNA (miRNA)-induced degradation" other hsa-mir-143 Colorectal Carcinoma 30195762 "sequester miR-135a, miR-143, miR-214, and miR-1271, protecting ANLN, BIRC5, IPO7, KIF2A, and KIF23 from microRNA (miRNA)-induced degradation" other hsa-mir-214 Colorectal Carcinoma 30195762 "sequester miR-135a, miR-143, miR-214, and miR-1271, protecting ANLN, BIRC5, IPO7, KIF2A, and KIF23 from microRNA (miRNA)-induced degradation" other hsa-mir-501 Gastric Neoplasms 30195794 miR-501 might be a potential target for doxorubicin resistance and gastric cancer therapy other hsa-mir-126 Johne Disease 30197143 "A model was developed using a combination of 4 miRNA (miR-1976, miR-873-3p, miR-520f-3p, and miR-126-3p), which distinguished moderate and severely infected animals from noninfected animal" other hsa-mir-1976 Johne Disease 30197143 "A model was developed using a combination of 4 miRNA (miR-1976, miR-873-3p, miR-520f-3p, and miR-126-3p), which distinguished moderate and severely infected animals from noninfected animal" other hsa-mir-520f Johne Disease 30197143 "A model was developed using a combination of 4 miRNA (miR-1976, miR-873-3p, miR-520f-3p, and miR-126-3p), which distinguished moderate and severely infected animals from noninfected animal" other hsa-mir-873 Johne Disease 30197143 "A model was developed using a combination of 4 miRNA (miR-1976, miR-873-3p, miR-520f-3p, and miR-126-3p), which distinguished moderate and severely infected animals from noninfected animal" other hsa-mir-193b Melanoma 30197759 "miR-193b and miR-30c-1* inhibit, whereas miR-576-5p enhances melanoma cell invasion in vitro." other hsa-mir-30c-1 Melanoma 30197759 "miR-193b and miR-30c-1* inhibit, whereas miR-576-5p enhances melanoma cell invasion in vitro." other hsa-mir-576 Melanoma 30197759 "miR-193b and miR-30c-1* inhibit, whereas miR-576-5p enhances melanoma cell invasion in vitro." other hsa-mir-143 Intracranial Aneurysm 30201338 The miR-143/145 cluster reverses the regulation effect of KLF5 in smooth muscle cells with proliferation and contractility in intracranial aneurysm. other hsa-mir-145 Intracranial Aneurysm 30201338 The miR-143/145 cluster reverses the regulation effect of KLF5 in smooth muscle cells with proliferation and contractility in intracranial aneurysm. other hsa-mir-9 "Carcinoma, Renal Cell" 30201928 miR-9-5p in Nephrectomy Specimens is a Potential Predictor of Primary Resistance to First-Line Treatment with Tyrosine Kinase Inhibitors in Patients with Metastatic Renal Cell Carcinoma. other hsa-mir-128 Inflammation 30203508 NEAT1 contributes to ox-LDL-induced inflammation and oxidative stress in macrophages through inhibiting miR-128. other hsa-mir-4633 Melanoma 30205394 Identification and Functional Evaluation of miR-4633-5p as a Biomarker and Tumor Suppressor in Metastatic Melanoma. other hsa-mir-21 "Fatty Liver, Non-Alcoholic" 30206377 Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model. other hsa-mir-520a "Carcinoma, Thyroid, Papillary" 30206929 "MicroRNA-520a-3p suppresses epithelial-mesenchymal transition, invasion, and migration of papillary thyroid carcinoma cells via the JAK1-mediated JAK/STAT signaling pathway." other hsa-mir-146a "Leukemia, Myeloid, Acute" 30208330 Upregulated microRNA-146a expression induced by granulocyte colony-stimulating factor enhanced low-dosage chemotherapy response in aged acute myeloid leukemia patients. other hsa-mir-122 Hepatitis C Virus Infection 30209483 Simple and rational design of a polymer nano-platform for high performance of HCV related miR-122 reduction in the liver. other hsa-mir-146a Obesity 30212608 Physical Activity Modulates the Overexpression of the Inflammatory miR-146a-5p in Obese Patients. other hsa-mir-200c "Carcinoma, Breast" 30213797 Reversal of Triple-negative Breast Cancer EMT by miR-200c Decreases Tryptophan Catabolism and a Program of Immune-Suppression. other hsa-mir-203 "Carcinoma, Lung, Non-Small-Cell" 30214583 H19 contributes to poor clinical features in NSCLC patients and leads to enhanced invasion in A549 cells through regulating miRNA-203-mediated epithelial-mesenchymal transition. other hsa-mir-214 Gastric Neoplasms 30215537 hsa_circ_0000993 may inhibit metastasis of gastric cancer through sequestering miR-214-5p other hsa-mir-198 "Lymphoma, Large B-Cell, Diffuse" 30216798 Bortezomib inhibited the progression of diffuse large B-cell lymphoma via targeting miR-198. other hsa-mir-27b "Adenocarcinoma, Esophageal" 30217293 microRNAs: Key regulators of chemotherapy response and metastatic potential via complex control of target pathways in esophageal adenocarcinoma. other hsa-mir-1290 "Carcinoma, Cervical" 30219071 Exosomal miR-1290 is a potential biomarker of high-grade serous ovarian carcinoma and can discriminate patients from those with malignancies of other histological types. other hsa-mir-146a Lung Injury [unspecific] 30220173 Effect and mechanism of MicroRNA-146a on TLR4 inflammatory signal pathway in the lung tissues of rats with mechanical ventilator-induced lung injury other hsa-mir-155 Acute Lung Injury 30220274 miR-155 ASO has the effect of inhibiting LPS-induced inflammatory response and improving prognosis in ALI mice other hsa-mir-142 Colon Neoplasms 30220706 BM-MSC-derived exosomes promote colon cancer stem cell-like traits via miR-142-3p other hsa-mir-30 "Carcinoma, Pancreatic" 30221677 Establishment of a non?coding RNAomics screening platform for the regulation of KRAS in pancreatic cancer by RNA sequencing. other hsa-mir-34 "Carcinoma, Pancreatic" 30221677 Establishment of a non?coding RNAomics screening platform for the regulation of KRAS in pancreatic cancer by RNA sequencing. other hsa-mir-320 Inflammation 30224451 IL-33 promotes recovery from acute colitis by inducing miR-320 to stimulate epithelial restitution and repair. other hsa-mir-124 Amyotrophic Lateral Sclerosis 30233312 we observed enhanced retrograde transport of miR-124-Cy3 other hsa-mir-199a "Diabetes Mellitus, Type 2" 30233719 Reduced expression of microRNA-199a-3p is associated with vascular endothelial cell injury induced by type 2 diabetes mellitus. other hsa-mir-191 Cholangiocarcinoma 30235453 miR-191 Inhibition Induces Apoptosis Through Reactivating Secreted Frizzled-Related Protein-1 in Cholangiocarcinoma. other hsa-mir-21 Neoplasms [unspecific] 30237038 "we discuss the role of miR-21 and miR-375 in the RAS pathway as well as their role in cancer diagnosis and progression, along with the role of other select miRNAs in cancer immune surveillance" other hsa-mir-375 Neoplasms [unspecific] 30237038 "we discuss the role of miR-21 and miR-375 in the RAS pathway as well as their role in cancer diagnosis and progression, along with the role of other select miRNAs in cancer immune surveillance" other hsa-mir-221 Neoplasms [unspecific] 30237739 The correlation between microRNA-221/222 cluster overexpression and malignancy: an updated meta-analysis including 2693 patients. other hsa-mir-222 Neoplasms [unspecific] 30237739 The correlation between microRNA-221/222 cluster overexpression and malignancy: an updated meta-analysis including 2693 patients. other hsa-mir-106 "Carcinoma, Hepatocellular" 30238497 Development and validation of serum exosomal microRNAs as diagnostic and prognostic biomarkers for hepatocellular carcinoma. other hsa-mir-17 Acute Respiratory Distress Syndrome 30239899 transfer of miR-17-5p strongly downregulated expression of the antiviral factor Mx1 and significantly enhanced IAV replication other hsa-let-7a "Leukemia, Lymphoblastic, Acute, T-Cell" 30241379 "we then showed the utility of the combination of three miRNAs as endogenous normalizers (hsa-miR-16-5p, hsa-miR-25-3p, and hsa-let-7a-5p)" other hsa-mir-16 "Leukemia, Lymphoblastic, Acute, T-Cell" 30241379 "we then showed the utility of the combination of three miRNAs as endogenous normalizers (hsa-miR-16-5p, hsa-miR-25-3p, and hsa-let-7a-5p)" other hsa-mir-25 "Leukemia, Lymphoblastic, Acute, T-Cell" 30241379 "we then showed the utility of the combination of three miRNAs as endogenous normalizers (hsa-miR-16-5p, hsa-miR-25-3p, and hsa-let-7a-5p)" other hsa-mir-34a Oral Neoplasms 30243489 Cancer-associated fibroblasts contribute to oral cancer cells proliferation and metastasis via exosome-mediated paracrine miR-34a-5p. other hsa-mir-142 Idiopathic Pulmonary Fibrosis 30244194 we found a negative correlation between miR-142-3p and diffusing capacity of the lungs for carbon monoxide/alveolar volume other hsa-mir-148a Ischemia-Reperfusion Injury 30244246 Role of miR-148a in Mitigating Hepatic Ischemia-Reperfusion Injury by Repressing the TLR4 Signaling Pathway via Targeting CaMKII¦Á in Vivo and in Vitro. other hsa-mir-126 Sepsis 30244405 Application of Deacetylated Poly-N-Acetyl Glucosamine Nanoparticles for the Delivery of miR-126 for the Treatment of Cecal Ligation and Puncture-Induced Sepsis. other hsa-mir-206 "Carcinoma, Lung, Non-Small-Cell" 30245277 "miR-206 and miR-613, were significantly associated with NSCLC" other hsa-mir-613 "Carcinoma, Lung, Non-Small-Cell" 30245277 "miR-206 and miR-613, were significantly associated with NSCLC" other hsa-mir-155 Asthma 30245919 MiR-155 may play a role in mediating allergic inflammation in T-cells and could be an anti-inflammatory target of steroids other hsa-mir-146a "Carcinoma, Breast" 30245930 "The role of miRNAs 34a, 146a, 320a and 542 in the synergistic anticancer effects of methyl 2-(5-fluoro-2-hydroxyphenyl)-1H- benzo[d]imidazole-5-carboxylate (MBIC) with doxorubicin in breast cancer cells." other hsa-mir-320a "Carcinoma, Breast" 30245930 "The role of miRNAs 34a, 146a, 320a and 542 in the synergistic anticancer effects of methyl 2-(5-fluoro-2-hydroxyphenyl)-1H- benzo[d]imidazole-5-carboxylate (MBIC) with doxorubicin in breast cancer cells." other hsa-mir-34a "Carcinoma, Breast" 30245930 "The role of miRNAs 34a, 146a, 320a and 542 in the synergistic anticancer effects of methyl 2-(5-fluoro-2-hydroxyphenyl)-1H- benzo[d]imidazole-5-carboxylate (MBIC) with doxorubicin in breast cancer cells." other hsa-mir-542 "Carcinoma, Breast" 30245930 "The role of miRNAs 34a, 146a, 320a and 542 in the synergistic anticancer effects of methyl 2-(5-fluoro-2-hydroxyphenyl)-1H- benzo[d]imidazole-5-carboxylate (MBIC) with doxorubicin in breast cancer cells." other hsa-mir-15a Neoplasms [unspecific] 30246332 The miR-15a/16 gene cluster in human cancer: A systematic review. other hsa-mir-16 Neoplasms [unspecific] 30246332 The miR-15a/16 gene cluster in human cancer: A systematic review. other hsa-mir-1271 Glioblastoma 30248541 Chemo-resistance of A172 glioblastoma cells is controlled by miR-1271-regulated Bcl-2. other hsa-mir-125a Gastrointestinal Stromal Tumor 30249101 Hsa-miR-28-5p and hsa-miR-125a-5p may be involved in the development and progression of GIST other hsa-mir-28 Gastrointestinal Stromal Tumor 30249101 Hsa-miR-28-5p and hsa-miR-125a-5p may be involved in the development and progression of GIST other hsa-mir-1247 "Carcinoma, Breast" 30249392 Downregulated miR-1247-5p associates with poor prognosis and facilitates tumor cell growth via DVL1/Wnt/¦Â-catenin signaling in breast cancer. other hsa-mir-23 Coronary Artery Disease 30249504 miR-23 regulates cell proliferation and apoptosis of vascular smooth muscle cells in coronary heart disease. other hsa-mir-195 "Carcinoma, Hepatocellular" 30249878 "Identification of potential transcription factors, long noncoding RNAs, and microRNAs associated with hepatocellular carcinoma." other hsa-mir-196a "Squamous Cell Carcinoma, Esophageal" 30249885 Association of serum annexin A1 with treatment response and prognosis in patients with esophageal squamous cell carcinoma. other hsa-mir-130a "Carcinoma, Breast" 30250584 Target gene prediction and pathway analysis revealed the involvement of miR-130a and miR-425 in pathways associated with malignant cell proliferation other hsa-mir-425 "Carcinoma, Breast" 30250584 Target gene prediction and pathway analysis revealed the involvement of miR-130a and miR-425 in pathways associated with malignant cell proliferation other hsa-mir-17 Small Intestine Carcinoma 30255827 Adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer prevention recommendations and WNT-pathway-related markers of bowel cancer risk. other hsa-mir-374a "Carcinoma, Hepatocellular" 30257238 "Propofol Inhibits Proliferation, Migration, Invasion and Promotes Apoptosis Through Down-Regulating miR-374a in Hepatocarcinoma Cell Lines." other hsa-mir-23a Hypoxia 30257251 Astragaloside IV Protects Rat Cardiomyocytes from Hypoxia-Induced Injury by Down-Regulation of miR-23a and miR-92a. other hsa-mir-92a Hypoxia 30257251 Astragaloside IV Protects Rat Cardiomyocytes from Hypoxia-Induced Injury by Down-Regulation of miR-23a and miR-92a. other hsa-mir-106b Neoplasms [unspecific] 30257332 The emerging roles of the polycistronic miR-106b?25 cluster in cancer - A comprehensive review. other hsa-mir-106 "Carcinoma, Bladder" 30257376 Baicalein inhibits proliferation and migration of bladder cancer cell line T24 by down-regulation of microRNA-106. other hsa-mir-18a Glioma 30257388 c-Fos/microRNA-18a feedback loop modulates the tumor growth via HMBOX1 in human gliomas. other hsa-mir-204 Diabetes Mellitus 30257973 miR-29c overexpression and miR-204 inhibition per se attenuated VSMC phenotypic switch in DM other hsa-mir-29c Diabetes Mellitus 30257973 miR-29c overexpression and miR-204 inhibition per se attenuated VSMC phenotypic switch in DM other hsa-mir-10a "Carcinoma, Breast" 30259272 MicroRNA Profiling of Salivary Duct Carcinoma Versus Her2/Neu Overexpressing Breast Carcinoma Identify miR-10a as a Putative Breast Related Oncogene. other hsa-mir-124a Cardiovascular Diseases [unspecific] 30260095 "Pearson analysis revealed a correlation between MPs miR-124a and miR150 and adiponectin, TNF¦Á, or IL-6 levels" other hsa-mir-150 Cardiovascular Diseases [unspecific] 30260095 "Pearson analysis revealed a correlation between MPs miR-124a and miR150 and adiponectin, TNF¦Á, or IL-6 levels" other hsa-let-7e Melanoma 30260323 "we describe a set of microRNAs (miR-146a, miR-155, miR-125b, miR-100, let-7e, miR-125a, miR-146b, miR-99b) that are associated with MDSCs and with resistance to treatment with immune checkpoint inhibitors in melanoma patients" other hsa-mir-100 Melanoma 30260323 "we describe a set of microRNAs (miR-146a, miR-155, miR-125b, miR-100, let-7e, miR-125a, miR-146b, miR-99b) that are associated with MDSCs and with resistance to treatment with immune checkpoint inhibitors in melanoma patients" other hsa-mir-125a Melanoma 30260323 "we describe a set of microRNAs (miR-146a, miR-155, miR-125b, miR-100, let-7e, miR-125a, miR-146b, miR-99b) that are associated with MDSCs and with resistance to treatment with immune checkpoint inhibitors in melanoma patients" other hsa-mir-125b Melanoma 30260323 "we describe a set of microRNAs (miR-146a, miR-155, miR-125b, miR-100, let-7e, miR-125a, miR-146b, miR-99b) that are associated with MDSCs and with resistance to treatment with immune checkpoint inhibitors in melanoma patients" other hsa-mir-146a Melanoma 30260323 "we describe a set of microRNAs (miR-146a, miR-155, miR-125b, miR-100, let-7e, miR-125a, miR-146b, miR-99b) that are associated with MDSCs and with resistance to treatment with immune checkpoint inhibitors in melanoma patients" other hsa-mir-146b Melanoma 30260323 "we describe a set of microRNAs (miR-146a, miR-155, miR-125b, miR-100, let-7e, miR-125a, miR-146b, miR-99b) that are associated with MDSCs and with resistance to treatment with immune checkpoint inhibitors in melanoma patients" other hsa-mir-155 Melanoma 30260323 "we describe a set of microRNAs (miR-146a, miR-155, miR-125b, miR-100, let-7e, miR-125a, miR-146b, miR-99b) that are associated with MDSCs and with resistance to treatment with immune checkpoint inhibitors in melanoma patients" other hsa-mir-99b Melanoma 30260323 "we describe a set of microRNAs (miR-146a, miR-155, miR-125b, miR-100, let-7e, miR-125a, miR-146b, miR-99b) that are associated with MDSCs and with resistance to treatment with immune checkpoint inhibitors in melanoma patients" other hsa-mir-350 Inflammation 30260716 miR-350-3p Contributes to Age-Associated Impairment of IL-6 Production by Macrophages. other hsa-mir-146a "Diabetes Mellitus, Type 1" 30260972 miR-146a-5p could play a role in type 1 diabetes development other hsa-mir-200 Lung Neoplasms 30268479 Exosomal RNA-profiling of pleural effusions identifies adenocarcinoma patients through elevated miR-200 and LCN2 expression. other hsa-mir-326 Cataract 30268497 MiR-326 antagomir delays the progression of age-related cataract by upregulating FGF1-mediated expression of betaB2-crystallin. other hsa-mir-145 Psoriasis 30269330 Downregulation of miR-145-5p contributes to hyperproliferation of keratinocytes and skin inflammation in psoriasis. other hsa-mir-122 "Fatty Liver, Non-Alcoholic" 30271077 "miR-34a, miR-122 and miR-155 are most involved in the pathogenesis of NAFLD" other hsa-mir-155 "Fatty Liver, Non-Alcoholic" 30271077 "miR-34a, miR-122 and miR-155 are most involved in the pathogenesis of NAFLD" other hsa-mir-34a "Fatty Liver, Non-Alcoholic" 30271077 "miR-34a, miR-122 and miR-155 are most involved in the pathogenesis of NAFLD" other hsa-mir-132 Myocardial Infarction 30271437 "MicroRNA-132, Delivered by Mesenchymal Stem Cell-Derived Exosomes, Promote Angiogenesis in Myocardial Infarction." other hsa-mir-3148 Neoplasms [unspecific] 30275189 miR-3148 Is a Novel Onco-microRNA that Potentiates Tumor Growth In Vivo. other hsa-mir-138 Neoplasms [unspecific] 30278099 apigenin-induced apoptotic rate was significantly higher when used in combination with miR-423-5p inhibitors or miR-138 mimics other hsa-mir-423 Neoplasms [unspecific] 30278099 apigenin-induced apoptotic rate was significantly higher when used in combination with miR-423-5p inhibitors or miR-138 mimics other hsa-mir-141 Aneurysm 30280445 The mir-200 family regulates key pathogenic events in ascending aortas of individuals with bicuspid aortic valves. other hsa-mir-200a Aneurysm 30280445 The mir-200 family regulates key pathogenic events in ascending aortas of individuals with bicuspid aortic valves. other hsa-mir-200b Aneurysm 30280445 The mir-200 family regulates key pathogenic events in ascending aortas of individuals with bicuspid aortic valves. other hsa-mir-200c Aneurysm 30280445 The mir-200 family regulates key pathogenic events in ascending aortas of individuals with bicuspid aortic valves. other hsa-mir-429 Aneurysm 30280445 The mir-200 family regulates key pathogenic events in ascending aortas of individuals with bicuspid aortic valves. other hsa-mir-378 Fatty Liver [unspecific] 30281809 LXR¦Á Promotes Hepatosteatosis in Part via Activation of MicroRNA-378 Transcription and Inhibition of Ppargc1¦Â Expression. other hsa-mir-223 Diabetes Mellitus 30287053 "celastrol reverses PA-induced IR-related alterations, in part via miR-223 in HepG2 cells" other hsa-mir-181a Osteoarthritis 30287418 microRNA-181a-5p antisense oligonucleotides attenuate osteoarthritis in facet and knee joints. other hsa-mir-495 Thrombosis 30287499 Effect of microRNA-495 on lower extremity deep vein thrombosis through the TLR4 signaling pathway by regulation of IL1R1. other hsa-mir-133a "Carcinoma, Oropharyngeal" 30289952 Smoking-induced control of miR-133a-3p alters the expression of EGFR and HuR in HPV-infected oropharyngeal cancer. other hsa-mir-296 Neoplasms [unspecific] 30293950 Epigenetic mechanisms and upstream transcription factors are responsible for the regulation of miR-296 expression in cancer other hsa-mir-15b Cardiovascular Diseases [unspecific] 30295821 "Our bioinformatic analysis revealed three highly expressed eNOS-targeting miRNAs (miR-15b, miR-16, and miR-30b) in human endothelial cells (ECs)" other hsa-mir-16 Cardiovascular Diseases [unspecific] 30295821 "Our bioinformatic analysis revealed three highly expressed eNOS-targeting miRNAs (miR-15b, miR-16, and miR-30b) in human endothelial cells (ECs)" other hsa-mir-30b Cardiovascular Diseases [unspecific] 30295821 "Our bioinformatic analysis revealed three highly expressed eNOS-targeting miRNAs (miR-15b, miR-16, and miR-30b) in human endothelial cells (ECs)" other hsa-mir-29a Intervertebral Disc Degeneration 30296017 Sustained and Bioresponsive Two-Stage Delivery of Therapeutic miRNA via Polyplex Micelle-Loaded Injectable Hydrogels for Inhibition of Intervertebral Disc Fibrosis. other hsa-mir-34 Heart Failure 30298011 Generation of MicroRNA-34 Sponges and Tough Decoys for the Heart: Developments and Challenges. other hsa-mir-101 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-10a Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-126 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-143 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-145 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-155 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-17 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-18 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-19a Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-19b-1 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-205 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-20a Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-21 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-23b Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-663 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-712 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-92-1 Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-92a Atherosclerosis 30300747 "miR-10a, -19a, -23b, -17~92, -21, -663, -92a, -143/145, -101, -126, -712, -205, and -155 that play a critical role in endothelial function and atherosclerosis by targeting inflammation, cell cycle, proliferation, migration, apoptosis, and nitric oxide signaling" other hsa-mir-155 "Carcinoma, Breast" 30301470 Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial. other hsa-mir-301 "Carcinoma, Breast" 30301470 Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial. other hsa-mir-155 Atrial Fibrillation 30302809 Ablation alleviates atrial fibrillation by regulating the signaling pathways of endothelial nitric oxide synthase/nitric oxide via miR-155-5p and miR-24-3p. other hsa-mir-24 Atrial Fibrillation 30302809 Ablation alleviates atrial fibrillation by regulating the signaling pathways of endothelial nitric oxide synthase/nitric oxide via miR-155-5p and miR-24-3p. other hsa-mir-125b "Carcinoma, Lung, Non-Small-Cell" 30305431 Reduced miR-125a-5p level in non-small-cell lung cancer is associated with tumour progression. other hsa-mir-194 Spinal Cord Injuries 30308510 Lycium Barbarum Polysaccharides Alleviates Oxidative Damage Induced by H2O2 Through Down-Regulating MicroRNA-194 in PC-12 and SH-SY5Y Cells. other hsa-mir-19a Giant Cell Tumor of Bone 30309658 Downregulation of miR-223 and miR-19a induces differentiation and promotes recruitment of osteoclast cells in giant-cell tumor of the bone via the Runx2/TWIST-RANK/RANKL pathway. other hsa-mir-223 Giant Cell Tumor of Bone 30309658 Downregulation of miR-223 and miR-19a induces differentiation and promotes recruitment of osteoclast cells in giant-cell tumor of the bone via the Runx2/TWIST-RANK/RANKL pathway. other hsa-mir-106a "Carcinoma, Breast" 30311168 "The three-miRNAs risk score (miR-19a, miR-93, and miR-106a) was developed using the TCGA cohort, which predicted poor prognosis (p?=?0.0005) independently of known clinical risk factors" other hsa-mir-19a "Carcinoma, Breast" 30311168 "The three-miRNAs risk score (miR-19a, miR-93, and miR-106a) was developed using the TCGA cohort, which predicted poor prognosis (p?=?0.0005) independently of known clinical risk factors" other hsa-mir-93 "Carcinoma, Breast" 30311168 "The three-miRNAs risk score (miR-19a, miR-93, and miR-106a) was developed using the TCGA cohort, which predicted poor prognosis (p?=?0.0005) independently of known clinical risk factors" other hsa-mir-494 Cholangiocarcinoma 30314946 "MicroRNA-494-dependent WDHDI inhibition suppresses epithelial-mesenchymal transition, tumor growth and metastasis in cholangiocarcinoma." other hsa-mir-224 Acute Coronary Syndrome 30317569 Downregulated microRNA-224 aggravates vulnerable atherosclerotic plaques and vascular remodeling in acute coronary syndrome through activation of the TGF-¦Â/Smad pathway. other hsa-mir-370 Diabetic Nephropathy 30317577 Effects of microRNA-370 on mesangial cell proliferation and extracellular matrix accumulation by binding to canopy 1 in a rat model of diabetic nephropathy. other hsa-mir-101 Neoplasms [unspecific] 30319254 Cationic graphene oxide nanoplatform mediates miR-101 delivery to promote apoptosis by regulating autophagy and stress. other hsa-mir-143 Glioblastoma 30322013 Targeting MicroRNA-143 Leads to Inhibition of Glioblastoma Tumor Progression. other hsa-mir-708 "Osteoporosis, Postmenopausal" 30322266 Identification of miR-708-5p in peripheral blood monocytes: Potential marker for postmenopausal osteoporosis in Mexican-Mestizo population. other hsa-mir-143 Helicobacter pylori Infection 30324743 "the expression of miR-28-3p, miR-143-3p, miR-151a-3p, and miR-148a-3p were closely associated with H pylori infection" other hsa-mir-148a Helicobacter pylori Infection 30324743 "the expression of miR-28-3p, miR-143-3p, miR-151a-3p, and miR-148a-3p were closely associated with H pylori infection" other hsa-mir-151a Helicobacter pylori Infection 30324743 "the expression of miR-28-3p, miR-143-3p, miR-151a-3p, and miR-148a-3p were closely associated with H pylori infection" other hsa-mir-28 Helicobacter pylori Infection 30324743 "the expression of miR-28-3p, miR-143-3p, miR-151a-3p, and miR-148a-3p were closely associated with H pylori infection" other hsa-mir-449a Osteoarthritis 30326428 Inhibition of miR-449a Promotes Cartilage Regeneration and Prevents Progression of Osteoarthritis in In?Vivo Rat Models. other hsa-mir-192 Polycystic Kidney Disease 30332302 Impact of miR-192 and miR-194 on cyst enlargement through EMT in autosomal dominant polycystic kidney disease. other hsa-mir-194 Polycystic Kidney Disease 30332302 Impact of miR-192 and miR-194 on cyst enlargement through EMT in autosomal dominant polycystic kidney disease. other hsa-mir-21 "Carcinoma, Cervical" 30332981 Deregulation of miR-21 and miR-29a in Cervical Cancer Related to HPV Infection. other hsa-mir-29a "Carcinoma, Cervical" 30332981 Deregulation of miR-21 and miR-29a in Cervical Cancer Related to HPV Infection. other hsa-mir-107 Graft-Versus-Host Disease 30333363 Decreased Expression of MicroRNA-107 in B Lymphocytes of Patients with Antibody-Mediated Renal Allograft Rejection. other hsa-mir-3158 "Diabetes Mellitus, Gestational" 30335885 "The key transcription factors include Sp1 transcription factor, pancreatic and duodenal homeobox 1, and hepatocyte nuclear factor 4 alpha, whereas miRNA includes has-miR-5699-5p and has-miR-3158-3p" other hsa-mir-5699 "Diabetes Mellitus, Gestational" 30335885 "The key transcription factors include Sp1 transcription factor, pancreatic and duodenal homeobox 1, and hepatocyte nuclear factor 4 alpha, whereas miRNA includes has-miR-5699-5p and has-miR-3158-3p" other hsa-mir-315 White Spot Syndrome Virus Infection 30337920 White Spot Syndrome Virus-Induced Shrimp miR-315 Attenuates Prophenoloxidase Activation via PPAE3 Gene Suppression. other hsa-mir-711 Ischemic Diseases [unspecific] 30338821 Dexmedetomidine protects liver cell line L-02 from oxygen-glucose deprivation-induced injury by down-regulation of microRNA-711. other hsa-mir-485 "Carcinoma, Pancreatic" 30341009 Bioselection Reveals miR-99b and miR-485 as Enhancers of Adenoviral Oncolysis in Pancreatic Cancer. other hsa-mir-99b "Carcinoma, Pancreatic" 30341009 Bioselection Reveals miR-99b and miR-485 as Enhancers of Adenoviral Oncolysis in Pancreatic Cancer. other hsa-mir-133a Lung Neoplasms 30341388 Up-regulated miR-133a orchestrates epithelial-mesenchymal transition of airway epithelial cells. other hsa-mir-132 Psychiatric Disorders 30342060 miR-132/212 is induced by stress and its dysregulation triggers anxiety-related behavior. other hsa-mir-212 Psychiatric Disorders 30342060 miR-132/212 is induced by stress and its dysregulation triggers anxiety-related behavior. other hsa-mir-31 "Carcinoma, Hepatocellular" 30342168 CircRNA has_circ_0078710 acts as the sponge of microRNA-31 involved in hepatocellular carcinoma progression. other hsa-mir-19b "Carcinoma, Breast" 30343695 MiR-19b non-canonical binding is directed by HuR and confers chemosensitivity through regulation of P-glycoprotein in breast cancer. other hsa-mir-122 Fatty Liver [unspecific] 30344495 "High Fat Diet-Induced miR-122 Regulates Lipid Metabolism and Fat Deposition in Genetically Improved Farmed Tilapia (GIFT, Oreochromis niloticus) Liver." other hsa-mir-146a Coronary Artery Disease 30344699 Endothelial stem cells attenuate cardiac apoptosis via downregulating cardiac microRNA-146a in a rat model of coronary heart disease. other hsa-mir-21 Neoplasms [unspecific] 30346694 Tumor Cell-Derived Extracellular Vesicle-Coated Nanocarriers: An Efficient Theranostic Platform for the Cancer-Specific Delivery of Anti-miR-21 and Imaging Agents. other hsa-mir-28 "Leukemia, Lymphocytic, Chronic, B-Cell" 30348117 NDRG2 mRNA levels and miR-28-5p and miR-650 activity in chronic lymphocytic leukemia. other hsa-mir-650 "Leukemia, Lymphocytic, Chronic, B-Cell" 30348117 NDRG2 mRNA levels and miR-28-5p and miR-650 activity in chronic lymphocytic leukemia. other hsa-mir-106b "Carcinoma, Breast" 30348127 "Several age-related miRNAs correlated with clinical frailty (miR-106b, miR-191, miR-301a, miR-320b, miR-374a), as well as with other biomarkers of aging, particularly Interleukin-6 (IL-6) and Monocyte Chemoattractant Protein-1 (MCP-1) (miR-106b, miR-301a, miR-374a-5p, miR-378a-3p)" other hsa-mir-191 "Carcinoma, Breast" 30348127 "Several age-related miRNAs correlated with clinical frailty (miR-106b, miR-191, miR-301a, miR-320b, miR-374a), as well as with other biomarkers of aging, particularly Interleukin-6 (IL-6) and Monocyte Chemoattractant Protein-1 (MCP-1) (miR-106b, miR-301a, miR-374a-5p, miR-378a-3p)" other hsa-mir-301a "Carcinoma, Breast" 30348127 "Several age-related miRNAs correlated with clinical frailty (miR-106b, miR-191, miR-301a, miR-320b, miR-374a), as well as with other biomarkers of aging, particularly Interleukin-6 (IL-6) and Monocyte Chemoattractant Protein-1 (MCP-1) (miR-106b, miR-301a, miR-374a-5p, miR-378a-3p)" other hsa-mir-320b "Carcinoma, Breast" 30348127 "Several age-related miRNAs correlated with clinical frailty (miR-106b, miR-191, miR-301a, miR-320b, miR-374a), as well as with other biomarkers of aging, particularly Interleukin-6 (IL-6) and Monocyte Chemoattractant Protein-1 (MCP-1) (miR-106b, miR-301a, miR-374a-5p, miR-378a-3p)" other hsa-mir-374a "Carcinoma, Breast" 30348127 "Several age-related miRNAs correlated with clinical frailty (miR-106b, miR-191, miR-301a, miR-320b, miR-374a), as well as with other biomarkers of aging, particularly Interleukin-6 (IL-6) and Monocyte Chemoattractant Protein-1 (MCP-1) (miR-106b, miR-301a, miR-374a-5p, miR-378a-3p)" other hsa-mir-6798 Glioblastoma 30349053 Ars2 promotes cell proliferation and tumorigenicity in glioblastoma through regulating miR-6798-3p. other hsa-mir-132 Neuropsychiatric Disorders [unspecific] 30352481 MicroRNA-132 directs human periodontal ligament-derived neural crest stem cell neural differentiation. other hsa-mir-34a "Carcinoma, Cervical" 30354014 co-incubation of these two MINRCs with U87MG and HeLa cells led to cell-selective delivery of miR-34a other hsa-mir-148b IgA Nephropathy 30355654 Renal microRNA-148b is associated with megalin downregulation in IgA nephropathy. other hsa-mir-122 Sepsis 30355788 "a group of host cellular microRNAs (miRNAs; miR-34a-5p, miR-122-5p, miR-145-5p, miR-146a-5p, miR-210-3p) are released into the blood during sepsis, some of which are capable of inducing complement activation, cytokine production, and leukocyte migration" other hsa-mir-145 Sepsis 30355788 "a group of host cellular microRNAs (miRNAs; miR-34a-5p, miR-122-5p, miR-145-5p, miR-146a-5p, miR-210-3p) are released into the blood during sepsis, some of which are capable of inducing complement activation, cytokine production, and leukocyte migration" other hsa-mir-146a Sepsis 30355788 "a group of host cellular microRNAs (miRNAs; miR-34a-5p, miR-122-5p, miR-145-5p, miR-146a-5p, miR-210-3p) are released into the blood during sepsis, some of which are capable of inducing complement activation, cytokine production, and leukocyte migration" other hsa-mir-210 Sepsis 30355788 "a group of host cellular microRNAs (miRNAs; miR-34a-5p, miR-122-5p, miR-145-5p, miR-146a-5p, miR-210-3p) are released into the blood during sepsis, some of which are capable of inducing complement activation, cytokine production, and leukocyte migration" other hsa-mir-34a Sepsis 30355788 "a group of host cellular microRNAs (miRNAs; miR-34a-5p, miR-122-5p, miR-145-5p, miR-146a-5p, miR-210-3p) are released into the blood during sepsis, some of which are capable of inducing complement activation, cytokine production, and leukocyte migration" other hsa-mir-224 Colorectal Carcinoma 30361904 "The study highlighted the involvement of non-target genes VEGFA, TGF¦Â1, IGF1, CD105 and CD44 in mediating anti- and pro-migratory effect of miR-375 and miR-224, respectively, and validated MAP4K4 as a direct target of anti-migratory miR-145" other hsa-mir-375 Colorectal Carcinoma 30361904 "The study highlighted the involvement of non-target genes VEGFA, TGF¦Â1, IGF1, CD105 and CD44 in mediating anti- and pro-migratory effect of miR-375 and miR-224, respectively, and validated MAP4K4 as a direct target of anti-migratory miR-145" other hsa-mir-1972 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 30362598 hsa-miR-20a-3p and hsa-miR-1972 were noted to be important in the etiology of larynx cancer other hsa-mir-20a "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 30362598 hsa-miR-20a-3p and hsa-miR-1972 were noted to be important in the etiology of larynx cancer other hsa-mir-126 "Carcinoma, Lung, Small-Cell" 30364292 "MiR-126, DACH1, GRM8, MET, GSR, and HCP5 were implicated in the lymph node metastasis process of SCLC" other hsa-mir-27a "Carcinoma, Breast" 30365154 miR?27a promotes human breast cancer cell migration by inducing EMT in a FBXW7?dependent manner. other hsa-mir-34a Stroke 30365981 MiR-34a and stroke: Assessment of non-modifiable biological risk factors in cerebral ischemia. other hsa-mir-146a Behcet Disease 30366049 Determination of mir-155 and mir-146a expression rates and its association with expression level of TNF-¦Á and CTLA4 genes in patients with Behcet's disease. other hsa-mir-155 Behcet Disease 30366049 Determination of mir-155 and mir-146a expression rates and its association with expression level of TNF-¦Á and CTLA4 genes in patients with Behcet's disease. other hsa-mir-135 "Diabetes Mellitus, Type 2" 30368872 "Network of three specific microRNAs(miR-135, miR-202, and miR-214) influence type 2 diabetes through inducing insulin resistance in muscle cell lines." other hsa-mir-202 "Diabetes Mellitus, Type 2" 30368872 "Network of three specific microRNAs(miR-135, miR-202, and miR-214) influence type 2 diabetes through inducing insulin resistance in muscle cell lines." other hsa-mir-214 "Diabetes Mellitus, Type 2" 30368872 "Network of three specific microRNAs(miR-135, miR-202, and miR-214) influence type 2 diabetes through inducing insulin resistance in muscle cell lines." other hsa-mir-155 Atherosclerosis 30369883 Increased Expression of Resistin in MicroRNA-155-Deficient White Adipose Tissues May Be a Possible Driver of Metabolically Healthy Obesity Transition to Classical Obesity. other hsa-mir-31 Neoplasms [unspecific] 30372817 Functions and mechanisms of microRNA-31 in human cancers. other hsa-mir-378 Muscular Dystrophy 30373812 microRNA-378 promotes autophagy and inhibits apoptosis in skeletal muscle. other hsa-mir-22 Hypertension 30375479 platelet miR-22 and miR-223 levels are reduced according to the hypertension status and they are negatively correlated with SBP levels other hsa-mir-223 Hypertension 30375479 platelet miR-22 and miR-223 levels are reduced according to the hypertension status and they are negatively correlated with SBP levels other hsa-mir-144 "Squamous Cell Carcinoma, Lung" 30375717 Involvement of dual-strand of the miR-144 duplex and their targets in the pathogenesis of lung squamous cell carcinoma. other hsa-mir-122 "Carcinoma, Hepatocellular" 30377095 "we unveiled how HBV is deciphering the cellular miRNAs like miR-26a, miR-15a, miR-16-1, miR-148a, miR-132, miR-122, miR-34a, miR-21, miR-29a, miR-222 and miR-199a/b-3p to modulate the Wnt/FZD/¦Â-catenin signaling pathway and develop HCC" other hsa-mir-132 "Carcinoma, Hepatocellular" 30377095 "we unveiled how HBV is deciphering the cellular miRNAs like miR-26a, miR-15a, miR-16-1, miR-148a, miR-132, miR-122, miR-34a, miR-21, miR-29a, miR-222 and miR-199a/b-3p to modulate the Wnt/FZD/¦Â-catenin signaling pathway and develop HCC" other hsa-mir-148a "Carcinoma, Hepatocellular" 30377095 "we unveiled how HBV is deciphering the cellular miRNAs like miR-26a, miR-15a, miR-16-1, miR-148a, miR-132, miR-122, miR-34a, miR-21, miR-29a, miR-222 and miR-199a/b-3p to modulate the Wnt/FZD/¦Â-catenin signaling pathway and develop HCC" other hsa-mir-15a "Carcinoma, Hepatocellular" 30377095 "we unveiled how HBV is deciphering the cellular miRNAs like miR-26a, miR-15a, miR-16-1, miR-148a, miR-132, miR-122, miR-34a, miR-21, miR-29a, miR-222 and miR-199a/b-3p to modulate the Wnt/FZD/¦Â-catenin signaling pathway and develop HCC" other hsa-mir-16 "Carcinoma, Hepatocellular" 30377095 "we unveiled how HBV is deciphering the cellular miRNAs like miR-26a, miR-15a, miR-16-1, miR-148a, miR-132, miR-122, miR-34a, miR-21, miR-29a, miR-222 and miR-199a/b-3p to modulate the Wnt/FZD/¦Â-catenin signaling pathway and develop HCC" other hsa-mir-199a "Carcinoma, Hepatocellular" 30377095 "we unveiled how HBV is deciphering the cellular miRNAs like miR-26a, miR-15a, miR-16-1, miR-148a, miR-132, miR-122, miR-34a, miR-21, miR-29a, miR-222 and miR-199a/b-3p to modulate the Wnt/FZD/¦Â-catenin signaling pathway and develop HCC" other hsa-mir-199b "Carcinoma, Hepatocellular" 30377095 "we unveiled how HBV is deciphering the cellular miRNAs like miR-26a, miR-15a, miR-16-1, miR-148a, miR-132, miR-122, miR-34a, miR-21, miR-29a, miR-222 and miR-199a/b-3p to modulate the Wnt/FZD/¦Â-catenin signaling pathway and develop HCC" other hsa-mir-21 "Carcinoma, Hepatocellular" 30377095 "we unveiled how HBV is deciphering the cellular miRNAs like miR-26a, miR-15a, miR-16-1, miR-148a, miR-132, miR-122, miR-34a, miR-21, miR-29a, miR-222 and miR-199a/b-3p to modulate the Wnt/FZD/¦Â-catenin signaling pathway and develop HCC" other hsa-mir-222 "Carcinoma, Hepatocellular" 30377095 "we unveiled how HBV is deciphering the cellular miRNAs like miR-26a, miR-15a, miR-16-1, miR-148a, miR-132, miR-122, miR-34a, miR-21, miR-29a, miR-222 and miR-199a/b-3p to modulate the Wnt/FZD/¦Â-catenin signaling pathway and develop HCC" other hsa-mir-26a "Carcinoma, Hepatocellular" 30377095 "we unveiled how HBV is deciphering the cellular miRNAs like miR-26a, miR-15a, miR-16-1, miR-148a, miR-132, miR-122, miR-34a, miR-21, miR-29a, miR-222 and miR-199a/b-3p to modulate the Wnt/FZD/¦Â-catenin signaling pathway and develop HCC" other hsa-mir-29a "Carcinoma, Hepatocellular" 30377095 "we unveiled how HBV is deciphering the cellular miRNAs like miR-26a, miR-15a, miR-16-1, miR-148a, miR-132, miR-122, miR-34a, miR-21, miR-29a, miR-222 and miR-199a/b-3p to modulate the Wnt/FZD/¦Â-catenin signaling pathway and develop HCC" other hsa-mir-34a "Carcinoma, Hepatocellular" 30377095 "we unveiled how HBV is deciphering the cellular miRNAs like miR-26a, miR-15a, miR-16-1, miR-148a, miR-132, miR-122, miR-34a, miR-21, miR-29a, miR-222 and miR-199a/b-3p to modulate the Wnt/FZD/¦Â-catenin signaling pathway and develop HCC" other hsa-mir-122 Liver Neoplasms 30378424 Multiple MicroRNA Quantification Based on Acoustic Levitation of Single Microspheres after One-Pot Sandwich Interparticle Hybridizations. other hsa-mir-21 Liver Neoplasms 30378424 Multiple MicroRNA Quantification Based on Acoustic Levitation of Single Microspheres after One-Pot Sandwich Interparticle Hybridizations. other hsa-mir-168 Colorectal Carcinoma 30378765 "Plant-derived miR-168 is ubiquitously present in feces, normal mucosa and cancer" other hsa-mir-155 Leukemia 30382602 "we discuss miR-155 dose-dependent effects in leukemias, and analyze results showing that miR-155 intermediate levels tend to be detrimental, while high levels of miR-155 expression usually prove beneficial" other hsa-mir-105 Amyotrophic Lateral Sclerosis 30385300 MiR-105 and miR-9 regulate the mRNA stability of neuronal intermediate filaments. Implications for the pathogenesis of amyotrophic lateral sclerosis (ALS). other hsa-mir-9 Amyotrophic Lateral Sclerosis 30385300 MiR-105 and miR-9 regulate the mRNA stability of neuronal intermediate filaments. Implications for the pathogenesis of amyotrophic lateral sclerosis (ALS). other hsa-mir-30a Colorectal Carcinoma 30387187 miR-30a promoter variation contributes to the increased risk of colorectal cancer in an Iranian population. other hsa-mir-21 Ischemia-Reperfusion Injury 23988020 "Our results demonstrate that besides miR-21, miR-17-5p, and miR-106a are additionally activated during the maintenance and recovery phases of renal I/R injury." other hsa-mir-17 Ischemia-Reperfusion Injury 23988020 "Our results demonstrate that besides miR-21, miR-17-5p, and miR-106a are additionally activated during the maintenance and recovery phases of renal I/R injury." other hsa-mir-106a Ischemia-Reperfusion Injury 23988020 "Our results demonstrate that besides miR-21, miR-17-5p, and miR-106a are additionally activated during the maintenance and recovery phases of renal I/R injury." lncRNA target hsa-let-7a-1 Neoplasms [unspecific] 19211792 let-7a: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation lncRNA target hsa-let-7a-2 Neoplasms [unspecific] 19211792 let-7a: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation lncRNA target hsa-let-7a-3 Neoplasms [unspecific] 19211792 let-7a: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation lncRNA target hsa-let-7b Neoplasms [unspecific] 19211792 let-7b: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation lncRNA target hsa-let-7c Neoplasms [unspecific] 19211792 let-7c: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation lncRNA target hsa-let-7d Neoplasms [unspecific] 19211792 let-7d: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation lncRNA target hsa-let-7e Neoplasms [unspecific] 19211792 let-7e: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation lncRNA target hsa-let-7f-1 Neoplasms [unspecific] 19211792 let-7f: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation lncRNA target hsa-let-7f-2 Neoplasms [unspecific] 19211792 let-7f: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation lncRNA target hsa-let-7g Neoplasms [unspecific] 19211792 let-7g: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation lncRNA target hsa-let-7i Neoplasms [unspecific] 19211792 let-7i: Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation lncRNA target hsa-let-7g Lung Neoplasms 19745602 increased with response to ionizing radiation when knockdown LIN28B lncRNA target hsa-let-7a-1 Neoplasms [unspecific] 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras lncRNA target hsa-let-7a-2 Neoplasms [unspecific] 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras lncRNA target hsa-let-7a-3 Neoplasms [unspecific] 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras lncRNA target hsa-let-7b Neoplasms [unspecific] 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras lncRNA target hsa-let-7c Neoplasms [unspecific] 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras lncRNA target hsa-let-7d Neoplasms [unspecific] 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras lncRNA target hsa-let-7e Neoplasms [unspecific] 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras lncRNA target hsa-let-7f-1 Neoplasms [unspecific] 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras lncRNA target hsa-let-7f-2 Neoplasms [unspecific] 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras lncRNA target hsa-let-7g Neoplasms [unspecific] 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras lncRNA target hsa-let-7i Neoplasms [unspecific] 20005451 Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras lncRNA target hsa-let-7a Retinal Degeneration 20935637 The opposing actions of Lin-28 and let-7 miRNAs on M¨¹ller glia differentiation and dedifferentiation are similar to that of embryonic stem cells and suggest novel targets for stimulating M¨¹ller glia dedifferentiation and retinal regeneration in mammals. lncRNA target hsa-let-7b Retinal Degeneration 20935637 The opposing actions of Lin-28 and let-7 miRNAs on M¨¹ller glia differentiation and dedifferentiation are similar to that of embryonic stem cells and suggest novel targets for stimulating M¨¹ller glia dedifferentiation and retinal regeneration in mammals. lncRNA target hsa-let-7c Retinal Degeneration 20935637 The opposing actions of Lin-28 and let-7 miRNAs on M¨¹ller glia differentiation and dedifferentiation are similar to that of embryonic stem cells and suggest novel targets for stimulating M¨¹ller glia dedifferentiation and retinal regeneration in mammals. lncRNA target hsa-let-7d Retinal Degeneration 20935637 The opposing actions of Lin-28 and let-7 miRNAs on M¨¹ller glia differentiation and dedifferentiation are similar to that of embryonic stem cells and suggest novel targets for stimulating M¨¹ller glia dedifferentiation and retinal regeneration in mammals. lncRNA target hsa-let-7e Retinal Degeneration 20935637 The opposing actions of Lin-28 and let-7 miRNAs on M¨¹ller glia differentiation and dedifferentiation are similar to that of embryonic stem cells and suggest novel targets for stimulating M¨¹ller glia dedifferentiation and retinal regeneration in mammals. lncRNA target hsa-let-7f Retinal Degeneration 20935637 The opposing actions of Lin-28 and let-7 miRNAs on M¨¹ller glia differentiation and dedifferentiation are similar to that of embryonic stem cells and suggest novel targets for stimulating M¨¹ller glia dedifferentiation and retinal regeneration in mammals. lncRNA target hsa-let-7g Retinal Degeneration 20935637 The opposing actions of Lin-28 and let-7 miRNAs on M¨¹ller glia differentiation and dedifferentiation are similar to that of embryonic stem cells and suggest novel targets for stimulating M¨¹ller glia dedifferentiation and retinal regeneration in mammals. lncRNA target hsa-let-7i Retinal Degeneration 20935637 The opposing actions of Lin-28 and let-7 miRNAs on M¨¹ller glia differentiation and dedifferentiation are similar to that of embryonic stem cells and suggest novel targets for stimulating M¨¹ller glia dedifferentiation and retinal regeneration in mammals. lncRNA target hsa-let-7a Neoplasms [unspecific] 21045151 "Our data provide evidence that cancer stem cells may arise through a ""reprogramming-like"" mechanism. A rebalancing of the LIN28/let-7 regulatory loop could be a novel therapeutic strategy to target ALDH1+ cancer stem cells." lncRNA target hsa-let-7b Neoplasms [unspecific] 21045151 "Our data provide evidence that cancer stem cells may arise through a ""reprogramming-like"" mechanism. A rebalancing of the LIN28/let-7 regulatory loop could be a novel therapeutic strategy to target ALDH1+ cancer stem cells." lncRNA target hsa-let-7c Neoplasms [unspecific] 21045151 "Our data provide evidence that cancer stem cells may arise through a ""reprogramming-like"" mechanism. A rebalancing of the LIN28/let-7 regulatory loop could be a novel therapeutic strategy to target ALDH1+ cancer stem cells." lncRNA target hsa-let-7d Neoplasms [unspecific] 21045151 "Our data provide evidence that cancer stem cells may arise through a ""reprogramming-like"" mechanism. A rebalancing of the LIN28/let-7 regulatory loop could be a novel therapeutic strategy to target ALDH1+ cancer stem cells." lncRNA target hsa-let-7e Neoplasms [unspecific] 21045151 "Our data provide evidence that cancer stem cells may arise through a ""reprogramming-like"" mechanism. A rebalancing of the LIN28/let-7 regulatory loop could be a novel therapeutic strategy to target ALDH1+ cancer stem cells." lncRNA target hsa-let-7f Neoplasms [unspecific] 21045151 "Our data provide evidence that cancer stem cells may arise through a ""reprogramming-like"" mechanism. A rebalancing of the LIN28/let-7 regulatory loop could be a novel therapeutic strategy to target ALDH1+ cancer stem cells." lncRNA target hsa-let-7g Neoplasms [unspecific] 21045151 "Our data provide evidence that cancer stem cells may arise through a ""reprogramming-like"" mechanism. A rebalancing of the LIN28/let-7 regulatory loop could be a novel therapeutic strategy to target ALDH1+ cancer stem cells." lncRNA target hsa-let-7i Neoplasms [unspecific] 21045151 "Our data provide evidence that cancer stem cells may arise through a ""reprogramming-like"" mechanism. A rebalancing of the LIN28/let-7 regulatory loop could be a novel therapeutic strategy to target ALDH1+ cancer stem cells." lncRNA target hsa-let-7a-1 Breast Neoplasms 22081076 LIN28: A regulator of tumor-suppressing activity of let-7 microRNA in human breast cancer. lncRNA target hsa-let-7a-2 Breast Neoplasms 22081076 LIN28: A regulator of tumor-suppressing activity of let-7 microRNA in human breast cancer. lncRNA target hsa-let-7a-3 Breast Neoplasms 22081076 LIN28: A regulator of tumor-suppressing activity of let-7 microRNA in human breast cancer. lncRNA target hsa-let-7c Breast Neoplasms 22081076 LIN28: A regulator of tumor-suppressing activity of let-7 microRNA in human breast cancer. lncRNA target hsa-let-7d Breast Neoplasms 22081076 LIN28: A regulator of tumor-suppressing activity of let-7 microRNA in human breast cancer. lncRNA target hsa-let-7f-1 Breast Neoplasms 22081076 LIN28: A regulator of tumor-suppressing activity of let-7 microRNA in human breast cancer. lncRNA target hsa-let-7f-2 Breast Neoplasms 22081076 LIN28: A regulator of tumor-suppressing activity of let-7 microRNA in human breast cancer. lncRNA target hsa-let-7a-1 Breast Neoplasms 22808086 "Lin28 Mediates Paclitaxel Resistance by Modulating p21, Rb and Let-7a miRNA in Breast Cancer Cells." lncRNA target hsa-let-7a-2 Breast Neoplasms 22808086 "Lin28 Mediates Paclitaxel Resistance by Modulating p21, Rb and Let-7a miRNA in Breast Cancer Cells." lncRNA target hsa-let-7a-3 Breast Neoplasms 22808086 "Lin28 Mediates Paclitaxel Resistance by Modulating p21, Rb and Let-7a miRNA in Breast Cancer Cells." lncRNA target hsa-let-7 Perlman Syndrome 23594738 A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. lncRNA target hsa-mir-221 Atherosclerosis 23697773 "We further discovered that an Ang II-regulated lncRNA functions as the host transcript for miR-221 and miR-222, 2 microRNAs implicated in cell proliferation. " lncRNA target hsa-mir-675 Gastric Neoplasms 24388988 The long non-coding RNA H19-derived miR-675 modulates human gastric cancer cell proliferation by targeting tumor suppressor RUNX1. lncRNA target hsa-mir-675 Glioma 24466011 Long non-coding RNA H19 promotes glioma cell invasion by deriving miR-675. lncRNA target hsa-mir-21 Osteoarthritis 25196583 "A long non-coding RNA, GAS5, plays a critical role in the regulation of miR-21 during osteoarthritis." lncRNA target hsa-mir-216b "Carcinoma, Hepatocellular" 25760077 Upregulated lncRNA-UCA1 contributes to progression of hepatocellular carcinoma through inhibition of miR-216b and activation of FGFR1/ERK signaling pathway. lncRNA target hsa-mir-193a "Leukemia, Myeloid, Acute" 25979172 Long non-coding RNA HOTAIR modulates c-KIT expression through sponging miR-193a in acute myeloid leukemia. lncRNA target hsa-mir-200c Gastric Neoplasms 25986864 LncRNA-ATB plays an important role in EMT to promote invasion and metastasis through the TGF-β/miR-200s/ZEB axis lncRNA target hsa-let-7 Melanoma 26071398 "we discovered that Lin28B, a well-characterized inhibitor of let-7 miRNA biogenesis, was a direct target of miR-125a-5p in melanoma." lncRNA target hsa-mir-107 Neoplasms [unspecific] 26158177 Lin28 could mediate cancer chemotherapy resistance via regulation of miR107 and Let-7 MiRNA. lncRNA target hsa-mir-152 Gastric Neoplasms 26187665 Long non-coding RNA HOTAIR promotes HLA-G expression via inhibiting miR-152 in gastric cancer cells. lncRNA target hsa-mir-145 Cervical Neoplasms 26311052 Long non-coding RNA MALAT1 modulates radiosensitivity of HR-HPV+ cervical cancer via sponging miR-145. lncRNA target hsa-let-7 Neoplasms [unspecific] 26440890 These findings refine the current model of let-7 regulation by LIN28 proteins and have important implications for understanding the LIN28/let-7 axis in development and disease. lncRNA target hsa-mir-222 Liver Fibrosis 26446789 GAS5 could directly bind to miR-222. lncRNA target hsa-mir-141 "Carcinoma, Renal Cell, Clear-Cell" 26461224 LncRNA MALAT1 functions as a competing endogenous RNA to regulate ZEB2 expression by sponging miR-200s in clear cell kidney carcinoma. lncRNA target hsa-mir-200a "Carcinoma, Renal Cell, Clear-Cell" 26461224 LncRNA MALAT1 functions as a competing endogenous RNA to regulate ZEB2 expression by sponging miR-200s in clear cell kidney carcinoma. lncRNA target hsa-mir-200b "Carcinoma, Renal Cell, Clear-Cell" 26461224 LncRNA MALAT1 functions as a competing endogenous RNA to regulate ZEB2 expression by sponging miR-200s in clear cell kidney carcinoma. lncRNA target hsa-mir-200c "Carcinoma, Renal Cell, Clear-Cell" 26461224 LncRNA MALAT1 functions as a competing endogenous RNA to regulate ZEB2 expression by sponging miR-200s in clear cell kidney carcinoma. lncRNA target hsa-mir-429 "Carcinoma, Renal Cell, Clear-Cell" 26461224 LncRNA MALAT1 functions as a competing endogenous RNA to regulate ZEB2 expression by sponging miR-200s in clear cell kidney carcinoma. lncRNA target hsa-mir-103 "Carcinoma, Endometrial" 26511107 "In summary, we demonstrate that GAS5 acts as an tumor suppressor lncRNA in endometrial cancer. Through inhibiting the expression of miR-103, GAS5 significantly enhanced the expression of PTEN to promote cancer cell apoptosis,and, thus, could be an important mediator in the pathogenesis of endometrial cancer." lncRNA target hsa-mir-320a Embryonal Testis Carcinoma 26539909 "The accumulation of NLC1-C in the nucleus repressed miR-320a and miR-383 transcript and promoted testicular embryonal carcinoma cell proliferation by binding to Nucleolin. Here, we define a novel mechanism by which lncRNAs modulate miRNA expression at the transcriptional level by binding to RNA-binding proteins to regulate human spermatogenesis." lncRNA target hsa-mir-193b "Adenocarcinoma, Pancreatic Ductal" 26549028 MIR31HG is negatively regulated by miR-193b. lncRNA target hsa-mir-107 Gastric Neoplasms 26636340 Our results suggest that the Lin28/miR-107 pathway could be one of many signaling pathways regulated by Lin28 and associated with gastric cancer chemo-resistance. lncRNA target hsa-mir-145 Pancreatic Neoplasms 26636540 ROR functions as a ceRNA to regulate Nanog expression by sponging miR-145 and predicts poor prognosis in pancreatic cancer. lncRNA target hsa-mir-194 "Carcinoma, Gallbladder" 26803515 "overexpression of H19 in GBC-SD cells downregulated miR-194-5p and markedly increased AKT2 expression, and miR-194-5p mimic reversed these effects." lncRNA target hsa-mir-485 Ovarian Neoplasms 26867765 UCA1 could function as an endogenous sponge by directly binding to miR-485-5p. lncRNA target hsa-mir-9 Atherosclerosis 26981838 HULC regulated TNF-α-induced apoptosis through regulation of miR-9 expression. lncRNA target hsa-mir-10a "Carcinoma, Hepatocellular" 27002617 Long non-coding RNA TUSC7 acts a molecular sponge for miR-10a and suppresses EMT in hepatocellular carcinoma. lncRNA target hsa-mir-204 "Carcinoma, Nasopharyngeal" 27020592 The long non-coding RNA NEAT1 regulates epithelial to mesenchymal transition and radioresistance in through miR-204/ZEB1 axis in nasopharyngeal carcinoma. lncRNA target hsa-mir-384 Glioma 27058823 "Moreover, CRNDE promoted cell malignant behavior by decreasing miR-384 expression." lncRNA target hsa-mir-374a "Carcinoma, Hepatocellular" 27065331 Long noncoding RNA FTX inhibits hepatocellular carcinoma proliferation and metastasis by binding MCM2 and miR-374a. lncRNA target hsa-mir-145 Colon Neoplasms 27071407 "Knockdown of lincRNA-ROR restored the expression of miR-145, and had a significant influence on colon cancer cell proliferation, migration and invasion." lncRNA target hsa-mir-206 Gastric Neoplasms 27192121 "Acting as a miR-206 sponge, RMRP modulated cell cycle by regulating Cyclin D2 expression." lncRNA target hsa-mir-218 Lung Neoplasms 27212446 miR-218 is negatively regulated by CCAT1 in HBE cells exposed to CSE. lncRNA target hsa-mir-143 Neuroblastoma 27263970 Binding and release of miR-143-3p by LncND control the expression of Notch receptors. lncRNA target hsa-mir-10a Glioblastoma 27270310 Long noncoding RNA RP11-838N2.4 enhances the cytotoxic effects of temozolomide by inhibiting the functions of miR-10a in glioblastoma cell lines. lncRNA target hsa-mir-299 Glioblastoma 27345398 TUG1 enhances tumor-induced angiogenesis and VEGF expression through inhibiting miR-299. lncRNA target hsa-mir-26a "Carcinoma, Gallbladder" 27345740 Upregulation of MINCR and enhancer of zeste homolog 2 (EZH2) in GBC coincided with the downregulation of miR-26a-5p in GBC. lncRNA target hsa-mir-26a Glioma 27363339 Long non-coding RNA TUG1 acts as a miR-26a sponge in human glioma cells lncRNA target hsa-mir-507 Melanoma 27389544 "We found that miR-507 could directly bind to UCA1 at the miRNA recognition site, and that there was a negative correlation between miR-507 and UCA1." lncRNA target hsa-mir-139 Glioma 27434586 "HCP5 regulated the malignant behavior of glioma cells by binding to microRNA-139, which functions as a tumor suppressor." lncRNA target hsa-mir-34a "Carcinoma, Nasopharyngeal" 27461945 Long non-coding RNA XIST exerts oncogenic functions in human nasopharyngeal carcinoma by targeting miR-34a-5p lncRNA target hsa-mir-373 "Carcinoma, Ovarian" 27484896 LncRNA HOTAIR controls the expression of Rab22a by sponging miR-373 in ovarian cancer. lncRNA target hsa-let-7a Cervical Neoplasms 27487126 LncRNA RSU1P2 contributes to tumorigenesis by acting as a ceRNA against let-7a in cervical cancer cells. lncRNA target hsa-mir-125a Immune Thrombocytopenic Purpura 27522004 Long non-coding RNA MEG3 inhibits microRNA-125a-5p expression and induces immune imbalance of Treg/Th17 in immune thrombocytopenic purpura. lncRNA target hsa-mir-34a Osteoarthritis 27529373 "Furthermore, we found that UFC1 regulates survival of OA chondrocytes through physically association with miR-34a." lncRNA target hsa-let-7 Neoplasms [unspecific] 27548809 "We anticipate that much can be learned from the use of this first reported small molecule antagonist of Lin28, including the potential of the Lin28/let-7 interaction as a new drug target for selected cancers" lncRNA target hsa-let-7c "Adenocarcinoma, Lung" 27566568 the oncogenic function of CCAT1 in docetaxel-resistant LAD cells depended on the sponging of let-7c lncRNA target hsa-mir-148a "Carcinoma, Cervical" 27574106 Long non-coding RNA HOTAIR modulates HLA-G expression by absorbing miR-148a in human cervical cancer. lncRNA target hsa-mir-196a "Carcinoma, Bladder" 27591936 Long non-coding RNA UCA1 promotes cisplatin/gemcitabine resistance through CREB modulating miR-196a-5p in bladder cancer cells. lncRNA target hsa-mir-140 "Carcinoma, Hepatocellular" 27597739 Long non-coding RNA Unigene56159 promotes epithelial-mesenchymal transition by acting as a ceRNA of miR-140-5p in hepatocellular carcinoma cells. lncRNA target hsa-mir-645 Osteosarcoma 27609068 Long non-coding RNA LINC00161 sensitises osteosarcoma cells to cisplatin-induced apoptosis by regulating the miR-645-IFIT2 axis. lncRNA target hsa-mir-181b Liver Cirrhosis 27610008 Identification of a Novel lincRNA-p21-miR-181b-PTEN Signaling Cascade in Liver Fibrosis. lncRNA target hsa-mir-18a "Carcinoma, Breast" 27629141 Long non-coding RNA UCA1 enhances tamoxifen resistance in breast cancer cells through a miR-18a-HIF1¦Á feedback regulatory loop. lncRNA target hsa-mir-197 "Carcinoma, Bladder" 27631965 LINC00312 inhibits the migration and invasion of bladder cancer cells by targeting miR-197-3p. lncRNA target hsa-mir-193a "Carcinoma, Colon" 27633443 the involvement of competing endogenous RNAs mechanism in Linc00152/miR-193a-3p/ERBB4/AKT signaling axis may provide a novel choice in the investigation of drug resistance lncRNA target hsa-mir-150 Myocardial Infarction 27649667 LncRNA MIAT enhances cardiac hypertrophy partly through sponging miR-150. lncRNA target hsa-mir-1297 "Carcinoma, Gastric" 27651312 "HOXA11-AS/miR-1297/EZH2 cross-talk serve as critical effectors in gastric cancer tumorigenesis and progression, suggesting new therapeutic directions in gastric cancer" lncRNA target hsa-mir-9 Osteosarcoma 27658774 Long non-coding RNA TUG1 contributes to tumorigenesis of human osteosarcoma by sponging miR-9-5p and regulating POU2F1 expression. lncRNA target hsa-mir-204 "Carcinoma, Esophageal" 27667646 lncRNA-UCA1 enhances cell proliferation through functioning as a ceRNA of Sox4 in esophageal cancer. lncRNA target hsa-mir-494 "Carcinoma, Hepatocellular" 27689326 An artificial lncRNA targeting multiple miRNAs overcomes sorafenib resistance in hepatocellular carcinoma cells. lncRNA target hsa-mir-140 Glioma 27693036 The lncRNA H19 interacts with miR-140 to modulate glioma growth by targeting iASPP. lncRNA target hsa-mir-200c "Carcinoma, Endometrioid Endometrial" 27693631 Disrupting MALAT1/miR-200c sponge decreases invasion and migration in endometrioid endometrial carcinoma. lncRNA target hsa-mir-27b "Carcinoma, Gastric" 27694794 Long Non-Coding RNA (LncRNA) Urothelial Carcinoma Associated 1 (UCA1) Increases Multi-Drug Resistance of Gastric Cancer via Downregulating miR-27b. lncRNA target hsa-mir-125b Leukemia 27740626 "HOTAIRM1 was revealed to act as a microRNA sponge in a pathway that included miR-20a/106b, miR-125b and their targets ULK1, E2F1 and DRAM2" lncRNA target hsa-mir-410 Glioma 27765628 Long non-coding RNA CCAT1 promotes glioma cell proliferation via inhibiting microRNA-410. lncRNA target hsa-mir-124 "Carcinoma, Pancreatic" 27785603 Linc-ROR confers gemcitabine resistance to pancreatic cancer cells via inducing autophagy and modulating the miR-124/PTBP1/PKM2 axis. lncRNA target hsa-mir-146a Prostate Neoplasms 27794184 LncRNA PVT1 regulates prostate cancer cell growth by inducing the methylation of miR-146a. lncRNA target hsa-mir-195 Osteosarcoma 27813492 Long non-coding RNA PVT1 promotes osteosarcoma development by acting as a molecular sponge to regulate miR-195. lncRNA target hsa-mir-200 "Carcinoma, Lung" 27852821 MEG3 regulated the recruitment of JARID2 and EZH2 and histone H3 methylation on the regulatory regions of CDH1 and microRNA-200 family genes for transcriptional repression lncRNA target hsa-mir-16 Leukemia 27854515 lncRNA UCA1 Contributes to Imatinib Resistance by Acting as a ceRNA Against miR-16 in Chronic Myeloid Leukemia Cells. lncRNA target hsa-mir-32 "Carcinoma, Gastric" 27871067 The lncRNA SNHG5/miR-32 axis regulates gastric cancer cell proliferation and migration by targeting KLF4. lncRNA target hsa-mir-107 Glioma 27878295 Silencing of the long non-coding RNA NEAT1 suppresses glioma stem-like properties through modulation of the miR-107/CDK6 pathway. lncRNA target hsa-mir-506 "Carcinoma, Pancreatic" 27888106 Long non-coding RNA NEAT1 facilitates pancreatic cancer progression through negative modulation of miR-506-3p. lncRNA target hsa-mir-206 "Carcinoma, Lung" 27906963 "RMRP acted as an oncogene LncRNA to promote the expression of KRAS, FMNL2 and SOX9 by inhibiting miR-206 expression in lung cancer" lncRNA target hsa-mir-195 "Carcinoma, Hepatocellular" 27932778 Expression of Long Non-Coding RNA (lncRNA) Small Nucleolar RNA Host Gene 1 (SNHG1) Exacerbates Hepatocellular Carcinoma Through Suppressing miR-195. lncRNA target hsa-mir-23c Diabetic Nephropathy 27964927 Long noncoding RNA MALAT1 regulates renal tubular epithelial pyroptosis by modulated miR-23c targeting of ELAVL1 in diabetic nephropathy. lncRNA target hsa-mir-183 Melanoma 27966454 Deregulation of miR-183 promotes melanoma development via lncRNA MALAT1 regulation and ITGB1 signal activation. lncRNA target hsa-mir-675 Glioma 27981546 "LncRNA H19 is overexpressed in glioma tissue, is negatively associated with patient survival, and promotes tumor growth through its derivative miR-675." lncRNA target hsa-mir-101 "Carcinoma, Bladder" 27998761 LncRNA SPRY4-IT1 sponges miR-101-3p to promote proliferation and metastasis of bladder cancer cells through up-regulating EZH2. lncRNA target hsa-mir-214 "Carcinoma, Thyroid" 28000845 Long non-coding RNA NEAT1 promotes malignant progression of thyroid carcinoma by regulating miRNA-214. lncRNA target hsa-mir-101 "Carcinoma, Breast" 28034643 The long non-coding RNA NEAT1 interacted with miR-101 modulates breast cancer growth by targeting EZH2. lncRNA target hsa-mir-15a "Carcinoma, Hepatocellular" 28035067 "Long non-coding RNA AK058003, as a precursor of miR-15a, interacts with HuR to inhibit the expression of ¦Ã-synuclein in hepatocellular carcinoma cells." lncRNA target hsa-mir-9 Breast Neoplasms 28053623 LncRNA Taurine-Upregulated Gene 1 Promotes Cell Proliferation by Inhibiting MicroRNA-9 in MCF-7 Cells. lncRNA target hsa-mir-204 Choriocarcinoma 28059437 "Long Non-Coding RNA MALAT1 Interacts With miR-204 to Modulate Human Hilar Cholangiocarcinoma Proliferation, Migration, and Invasion by Targeting CXCR4." lncRNA target hsa-mir-205 "Carcinoma, Breast" 28063065 Effects of long noncoding RNA-ROR on tamoxifen resistance of breast cancer cells by regulating microRNA-205. lncRNA target hsa-mir-200a "Leukemia, Myeloid, Chronic" 28069548 HULC could modulate c-Myc and Bcl-2 by miR-200a as an endogenous sponge lncRNA target hsa-mir-218 Colorectal Carcinoma 28069878 "the interaction between lncRNA MALAT1 and miR-218 was observed, which further indicated its prognostic value in patients who received standard FOLFOX treatment" lncRNA target hsa-let-7 Malignant Neoplasms [unspecific] 28076679 Molecular Dynamics Simulations for Deciphering the Structural Basis of Recognition of Pre-let-7 miRNAs by LIN28. lncRNA target hsa-mir-181a Colorectal Carcinoma 28086904 The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt/¦Â-catenin signaling. lncRNA target hsa-mir-218 Retinoblastoma 28088735 Long non-coding RNA CCAT1 promotes human retinoblastoma SO-RB50 and Y79 cells through negative regulation of miR-218-5p. lncRNA target hsa-mir-224 "Squamous Cell Carcinoma, Oral" 28093311 Long non-coding RNA FTH1P3 facilitates oral squamous cell carcinoma progression by acting as a molecular sponge of miR-224-5p to modulate fizzled 5 expression. lncRNA target hsa-let-7a "Carcinoma, Nasopharyngeal" 28117929 Downregulation of lncRNA ANRIL represses tumorigenicity and enhances cisplatin-induced cytotoxicity via regulating microRNA let-7a in nasopharyngeal carcinoma. lncRNA target hsa-mir-181a Glioma 28121023 LncRNA CASC2 Interacts With miR-181a to Modulate Glioma Growth and Resistance to TMZ Through PTEN Pathway. lncRNA target hsa-mir-186 "Carcinoma, Gastric" 28122299 The long noncoding RNA PVT1 functions as a competing endogenous RNA by sponging miR-186 in gastric cancer. lncRNA target hsa-mir-29b Liver Cirrhosis 28129115 HOTAIR Epigenetically Modulates PTEN Expression via MicroRNA-29b: A Novel Mechanism in Regulation of Liver Fibrosis. lncRNA target hsa-mir-100 "Carcinoma, Colon" 28130225 "Cellular Model of Colon Cancer Progression Reveals Signatures of mRNAs, miRNA, lncRNAs, and Epigenetic Modifications Associated with Metastasis." lncRNA target hsa-mir-125b "Carcinoma, Colon" 28130225 "Cellular Model of Colon Cancer Progression Reveals Signatures of mRNAs, miRNA, lncRNAs, and Epigenetic Modifications Associated with Metastasis." lncRNA target hsa-mir-99a "Carcinoma, Colon" 28130225 "Cellular Model of Colon Cancer Progression Reveals Signatures of mRNAs, miRNA, lncRNAs, and Epigenetic Modifications Associated with Metastasis." lncRNA target hsa-mir-182 Glioma 28137422 The lncRNA UCA1 interacts with miR-182 to modulate glioma proliferation and migration by targeting iASPP. lncRNA target hsa-mir-101 "Carcinoma, Lung, Non-Small-Cell" 28147312 Upregulated lncRNA SNHG1 contributes to progression of non-small cell lung cancer through inhibition of miR-101-3p and activation of Wnt/¦Â-catenin signaling pathway. lncRNA target hsa-mir-34c Inflammatory Bowel Diseases 28153728 MiR-34c and PlncRNA1 mediated the function of intestinal epithelial barrier by regulating tight junction proteins in inflammatory bowel disease. lncRNA target hsa-mir-200a Colorectal Carcinoma 28164117 The lncRNA H19 Promotes Cell Proliferation by Competitively Binding to miR-200a and Derepressing ¦Â-Catenin Expression in Colorectal Cancer. lncRNA target hsa-mir-300 "Carcinoma, Bladder" 28178615 Long non-coding RNA TUG1 promotes cell proliferation and metastasis by negatively regulating miR-300 in gallbladder carcinoma. lncRNA target hsa-mir-200 "Carcinoma, Breast" 28187158 Role of the long non-coding RNA PVT1 in the dysregulation of the ceRNA-ceRNA network in human breast cancer. lncRNA target hsa-mir-21 Leukemia 28190319 LncRNA MEG3 Regulates Imatinib Resistance in Chronic Myeloid Leukemia via Suppressing MicroRNA-21. lncRNA target hsa-mir-17 Non-Traumatic Osteonecrosis 28207735 Long non-coding RNA HOTAIR inhibits miR-17-5p to regulate osteogenic differentiation and proliferation in non-traumatic osteonecrosis of femoral head. lncRNA target hsa-mir-211 "Carcinoma, Colon" 28214867 The Novel Long Noncoding RNA TUSC7 Inhibits Proliferation by Sponging MiR-211 in Colorectal Cancer. lncRNA target hsa-mir-139 "Carcinoma, Hepatocellular" 28231734 Long non-coding RNA XIST promotes cell growth by regulating miR-139-5p/PDK1/AKT axis in hepatocellular carcinoma. lncRNA target hsa-mir-214 "Carcinoma, Nasopharyngeal" 28245169 Long Noncoding RNA LINC0086 Functions as a Tumor Suppressor in Nasopharyngeal Carcinoma by Targeting miR-214. lncRNA target hsa-mir-29b Diabetic Retinopathy 28246353 Long non-coding RNA MIAT acts as a biomarker in diabetic retinopathy by absorbing miR-29b and regulating cell apoptosis. lncRNA target hsa-mir-449a "Carcinoma, Lung, Non-Small-Cell" 28248928 "The lncRNA XIST exhibits oncogenic properties via regulation of miR-449a and Bcl-2 in human non-small cell lung cancerThis article has been corrected since Advanced Online Publication, and an erratum is also printed in this issue." lncRNA target hsa-mir-124 "Carcinoma, Tounge" 28260102 Long non-coding RNA MALAT1 interacts with miR-124 and modulates tongue cancer growth by targeting JAG1. lncRNA target hsa-mir-125b Hepatitis B Virus Infection 28267418 MicroRNA-125b-5p mediates post-transcriptional regulation of hepatitis B virus replication via the LIN28B/let-7 axis. lncRNA target hsa-mir-203 "Carcinoma, Hepatocellular" 28271214 Long non-coding RNA UCA1 regulates the expression of Snail2 by miR-203 to promote hepatocellular carcinoma progression. lncRNA target hsa-mir-204 Uterine Corpus Endometrial Carcinoma 28280730 Cancer-Related Triplets of mRNA-lncRNA-miRNA Revealed by Integrative Network in Uterine Corpus Endometrial Carcinoma. lncRNA target hsa-mir-320 Uterine Corpus Endometrial Carcinoma 28280730 Cancer-Related Triplets of mRNA-lncRNA-miRNA Revealed by Integrative Network in Uterine Corpus Endometrial Carcinoma. lncRNA target hsa-mir-150 Myocardial Infarction 28295592 Knockdown of Long Non-Coding RNA-ZFAS1 Protects Cardiomyocytes Against Acute Myocardial Infarction Via Anti-Apoptosis by Regulating miR-150/CRP. lncRNA target hsa-mir-200a Hepatitis C Virus Infection 28302418 LncRNA-ATB/microRNA-200a/¦Â-catenin regulatory axis involved in the progression of HCV-related hepatic fibrosis. lncRNA target hsa-mir-200b Hepatitis C Virus Infection 28302418 LncRNA-ATB/microRNA-200a/¦Â-catenin regulatory axis involved in the progression of HCV-related hepatic fibrosis. lncRNA target hsa-mir-24 "Carcinoma, Colon" 28306719 "Chromosome 19q13 disruption alters expressions of CYP2A7, MIA and MIA-RAB4B lncRNA and contributes to FAP-like phenotype in APC mutation-negative familial colorectal cancer patients." lncRNA target hsa-mir-770 Gastric Cardia Adenocarcinoma 28345805 "Promoter hypermethylation-mediated downregulation of miR-770 and its host gene MEG3, a long non-coding RNA, in the development of gastric cardia adenocarcinoma." lncRNA target hsa-mir-129 Osteosarcoma 28346809 MALAT1 promotes osteosarcoma development by regulation of HMGB1 via miR-142-3p and miR-129-5p. lncRNA target hsa-mir-142 Osteosarcoma 28346809 MALAT1 promotes osteosarcoma development by regulation of HMGB1 via miR-142-3p and miR-129-5p. lncRNA target hsa-mir-181a "Carcinoma, Nasopharyngeal" 28358263 LncRNA CCAT1 modulates the sensitivity of paclitaxel in nasopharynx cancers cells via miR-181a/CPEB2 axis. lncRNA target hsa-mir-138 "Carcinoma, Colon" 28358427 H19 promotes the migration and invasion of colon cancer by sponging miR-138 to upregulate the expression of HMGA1. lncRNA target hsa-mir-490 "Carcinoma, Colon" 28381168 Long non-coding RNA colon cancer-associated transcript 1 functions as a competing endogenous RNA to regulate cyclin-dependent kinase 1 expression by sponging miR-490-3p in hepatocellular carcinoma progression. lncRNA target hsa-mir-145 "Adenocarcinoma, Lung" 28388536 Long noncoding RNA ROR regulates chemoresistance in docetaxel-resistant lung adenocarcinoma cells via epithelial mesenchymal transition pathway. lncRNA target hsa-mir-199a "Carcinoma, Prostate" 28400279 SNHG1 lncRNA negatively regulates miR-199a-3p to enhance CDK7 expression and promote cell proliferation in prostate cancer. lncRNA target hsa-mir-200a "Carcinoma, Hepatocellular" 28403886 The long non-coding RNA TP73-AS1 modulates HCC cell proliferation through miR-200a-dependent HMGB1/RAGE regulation. lncRNA target hsa-mir-26b Melanoma 28409552 Long Noncoding RNA PVT1 Promotes Melanoma Progression via Endogenous Sponging miR-26b. lncRNA target hsa-mir-153 Osteosarcoma 28411362 Knockdown of Long Noncoding RNA TUG1 Inhibits the Proliferation and Cellular Invasion of Osteosarcoma Cells by Sponging miR-153. lncRNA target hsa-mir-210 Osteosarcoma 28415557 "lncRNA CTA is an essential regulator in DOX-induced OS cell apoptosis, and the lncRNA CTA-miR-210 axis plays an important role in reducing OS chemoresistance" lncRNA target hsa-mir-19b Medulloblastoma 28415684 The long noncoding RNA linc-NeD125 controls the expression of medulloblastoma driver genes by microRNA sponge activity. lncRNA target hsa-mir-372 "Carcinoma, Hepatocellular" 28415780 Long noncoding RNA PCAT-14 induces proliferation and invasion by hepatocellular carcinoma cells by inducing methylation of miR-372. lncRNA target hsa-mir-21 Glioblastoma 28423669 "The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells." lncRNA target hsa-mir-145 "Carcinoma, Oral" 28443494 Expression profiling of long non-coding RNA identifies linc-RoR as a prognostic biomarker in oral cancer. lncRNA target hsa-mir-186 "Carcinoma, Lung, Non-Small-Cell" 28448993 The Long Non-Coding RNA XIST Controls Non-Small Cell Lung Cancer Proliferation and Invasion by Modulating miR-186-5p. lncRNA target hsa-mir-495 "Carcinoma, Renal Cell" 28466784 LncRNA UCA1 promotes renal cell carcinoma proliferation through epigenetically repressing p21 expression and negatively regulating miR-495. lncRNA target hsa-mir-217 "Carcinoma, Colon" 28472810 The Long Non-Coding RNA CRNDE Promotes Colorectal Carcinoma Progression by Competitively Binding miR-217 with TCF7L2 and Enhancing the Wnt/¦Â-Catenin Signaling Pathway. lncRNA target hsa-mir-200b Melanoma 28487474 "Long noncoding RNA HEIH promotes melanoma cell proliferation, migration and invasion via inhibition of miR-200b/a/429." lncRNA target hsa-mir-429 Melanoma 28487474 "Long noncoding RNA HEIH promotes melanoma cell proliferation, migration and invasion via inhibition of miR-200b/a/429." lncRNA target hsa-mir-145 "Carcinoma, Gastric" 28490034 Long Noncoding RNA CRNDE Promotes Proliferation of Gastric Cancer Cells by Targeting miR-145. lncRNA target hsa-mir-26a Glioblastoma 28499919 Long non-coding RNA AC023115.3 suppresses chemoresistance of glioblastoma by reducing autophagy. lncRNA target hsa-mir-221 Osteosarcoma 28519068 Long Noncoding RNA GAS5 Suppresses Cell Growth and Epithelial-Mesenchymal Transition in Osteosarcoma by Regulating the miR-221/ARHI Pathway. lncRNA target hsa-mir-9 "Carcinoma, Hepatocellular" 28520103 Circular RNA circMTO1 acts as the sponge of microRNA-9 to suppress hepatocellular carcinoma progression. lncRNA target hsa-mir-21 Cardiac Fibrosis 28526319 LncRNA GAS5 controls cardiac fibroblast activation and fibrosis by targeting miR-21 via PTEN/MMP-2 signaling pathway. lncRNA target hsa-mir-129 "Carcinoma, Hepatocellular" 28526689 Long non-coding RNA NEAT1 promotes hepatocellular carcinoma cell proliferation through the regulation of miR-129-5p-VCP-I¦ÊB. lncRNA target hsa-mir-9 "Carcinoma, Esophageal" 28539329 Aberrant Methylation-Mediated Silencing of lncRNA MEG3 Functions as a ceRNA in Esophageal Cancer. lncRNA target hsa-mir-20a Neoplasms [unspecific] 28542387 LncRNA-AF113014 promotes the expression of Egr2 by interaction with miR-20a to inhibit proliferation of hepatocellular carcinoma cells. lncRNA target hsa-let-7 Pancreatic Neoplasms 28580169 "linc-ROR functioned as a competing endogenous RNA (ceRNA) to several tumor suppressor microRNAs, particularly some members of let-7 family" lncRNA target hsa-mir-7 Gastric Neoplasms 28608528 Overexpression of Circular RNA ciRS-7 Abrogates the Tumor Suppressive Effect of miR-7 on Gastric Cancer via PTEN/PI3K/AKT Signaling Pathway. lncRNA target hsa-mir-335 "Carcinoma, Gastric" 28618927 Long non-coding RNA MSTO2P promotes the proliferation and colony formation in gastric cancer by indirectly regulating miR-335 expression. lncRNA target hsa-mir-143 Colorectal Carcinoma 28619512 PART-1 functions as a competitive endogenous RNA for promoting tumor progression by sponging miR-143 in colorectal cancer. lncRNA target hsa-mir-218 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 28631575 Long non-coding RNA CCAT1/miR-218/ZFX axis modulates the progression of laryngeal squamous cell cancer. lncRNA target hsa-mir-214 "Carcinoma, Pancreatic" 28639886 "A competing endogenous RNA network identifies novel mRNA, miRNA and lncRNA markers for the prognosis of diabetic pancreatic cancer." lncRNA target hsa-mir-429 "Carcinoma, Pancreatic" 28639886 "A competing endogenous RNA network identifies novel mRNA, miRNA and lncRNA markers for the prognosis of diabetic pancreatic cancer." lncRNA target hsa-mir-200b "Squamous Cell Carcinoma, Esophageal" 28640252 Long non-coding RNA ATB promotes malignancy of esophageal squamous cell carcinoma by regulating miR-200b/Kindlin-2 axis. lncRNA target hsa-mir-23b "Carcinoma, Endometrial" 28653877 Long non-coding RNA tumor suppressor candidate 7 advances chemotherapy sensitivity of endometrial carcinoma through targeted silencing of miR-23b. lncRNA target hsa-mir-150 Lung Injury [unspecific] 28655711 Long noncoding RNA FOXD3-AS1 regulates oxidative stress-induced apoptosis via sponging microRNA-150. lncRNA target hsa-mir-186 "Carcinoma, Hepatocellular" 28656879 Long non-coding RNA PVT1 serves as a competing endogenous RNA for miR-186-5p to promote the tumorigenesis and metastasis of hepatocellular carcinoma. lncRNA target hsa-mir-196a "Carcinoma, Cervical" 28671039 LncRNA GAS5 suppresses the tumorigenesis of cervical cancer by downregulating miR-196a and miR-205. lncRNA target hsa-mir-205 "Carcinoma, Cervical" 28671039 LncRNA GAS5 suppresses the tumorigenesis of cervical cancer by downregulating miR-196a and miR-205. lncRNA target hsa-mir-17 Atherosclerosis 28676341 "The Circular RNA Interacts with STAT3, Increasing Its Nuclear Translocation and Wound Repair by Modulating Dnmt3a and miR-17 Function." lncRNA target hsa-let-7 "Leukemia, Myeloid, Acute" 28693523 "LIN28B/let-7/IGF2BP1, in leukemogenesis and provide a rationale to target this pathway as effective therapeutic strategy" lncRNA target hsa-mir-125b Osteosarcoma 28695772 "Circular RNA GLI2 promotes osteosarcoma cell proliferation, migration, and invasion by targeting miR-125b-5p." lncRNA target hsa-mir-204 "Carcinoma, Hepatocellular" 28720061 The long non-coding RNA MALAT1 promotes the migration and invasion of hepatocellular carcinoma by sponging miR-204 and releasing SIRT1. lncRNA target hsa-mir-101 "Carcinoma, Colon" 28720069 Long non-coding RNA SPRY4-IT1 promotes proliferation and invasion by acting as a ceRNA of miR-101-3p in colorectal cancer cells. lncRNA target hsa-mir-195 "Carcinoma, Hepatocellular" 28722813 Knockdown of long non-coding RNA MALAT1 inhibits growth and motility of human hepatoma cells via modulation of miR-195. lncRNA target hsa-mir-19a "Carcinoma, Hepatocellular" 28724429 its pro-metastatic phenotype can partially be attributed to the HOXD-AS1/miR19a/ARHGAP11A signaling axis lncRNA target hsa-mir-134 "Carcinoma, Nasopharyngeal" 28728844 Long non-coding RNA PCAT7 regulates ELF2 signaling through inhibition of miR-134-5p in nasopharyngeal carcinoma. lncRNA target hsa-mir-19b Breast Neoplasms 28731027 PTENP1 acts as a ceRNA to regulate PTEN by sponging miR-19b and explores the biological role of PTENP1 in breast cancer lncRNA target hsa-mir-92a Coronary Artery Disease 28760552 CDKN2B-AS may indirectly regulate coronary artery disease-associated genes via targeting miR-92a. lncRNA target hsa-mir-144 Lung Neoplasms 28762326 Long Noncoding RNA Urothelial Carcinoma Associated 1 Promotes the Proliferation and Metastasis of Human Lung Tumor Cells by Regulating MicroRNA-144. lncRNA target hsa-mir-29c Osteosarcoma 28789596 WITHDRAWN: Circular RNA hsa_circ_0001564 facilitates tumorigenesis of osteosarcoma via sponging miR-29c-3p. lncRNA target hsa-mir-21 Multiple Myeloma 28801664 "we identified microRNA-21 as a STAT3 target gene with strong anti-apoptotic potential, suggesting that noncoding RNAs have an impact on the pathogenesis of human multiple myeloma" lncRNA target hsa-mir-34a Osteosarcoma 28810936 "lncRNA C2dat1 Promotes Cell Proliferation, Migration, and Invasion by Targeting miR-34a-5p in Osteosarcoma Cells." lncRNA target hsa-mir-205 Neoplasms [unspecific] 28825698 Functionally the lncRNA-PNUTS serves as a competitive sponge for miR-205 during epithelial-mesenchymal transition (EMT) lncRNA target hsa-mir-150 Myocardial Infarction 28843520 The long non-coding RNA MIAT regulates zinc finger E-box binding homeobox 1 expression by sponging miR-150 and promoteing cell invasion in non-small-cell lung cancer. lncRNA target hsa-let-7 Neoplasms [unspecific] 28846452 "Concise Review: LIN28/let-7 Signaling, a Critical Double-Negative Feedback Loop During Pluripotency, Reprogramming, and Tumorigenicity." lncRNA target hsa-mir-106b "Carcinoma, Ovarian" 28864116 lncRNA PCA3 may coordinate EOC tumorigenesis through disrupting miR-106b regulated gene expression lncRNA target hsa-mir-138 "Carcinoma, Lung, Non-Small-Cell" 28872894 Knockdown of Long Noncoding RNA Small Nucleolar RNA Host Gene 12 Inhibits Cell Growth and Induces Apoptosis by Upregulating miR-138 in Nonsmall Cell Lung Cancer. lncRNA target hsa-mir-125b "Squamous Cell Carcinoma, Oral" 28926115 Long non-coding RNA MALAT1 promotes oral squamous cell carcinoma development via microRNA-125b/STAT3 axis. lncRNA target hsa-let-7 "Adenocarcinoma, Pancreatic Ductal" 28947981 "Lin28B, a Lin28 homologue, represses the biogenesis of let-7 microRNAs (miRNAs), has a role in tumorigenesis, and is considered a potential therapeutic target for various human malignancies" lncRNA target hsa-mir-21 Colon Neoplasms 28954383 Long non-coding RNA CASC7 inhibits the proliferation and migration of colon cancer cells via inhibiting microRNA-21. lncRNA target hsa-mir-31 Chordoma 28963737 Long non-coding RNA LOC554202 modulates chordoma cell proliferation and invasion by recruiting EZH2 and regulating miR-31 expression. lncRNA target hsa-mir-124 "Carcinoma, Lung, Non-Small-Cell" 29034803 LncRNA HOXA11-AS promotes proliferation and invasion by targeting miR-124 in human non-small cell lung cancer cells. lncRNA target hsa-mir-34a Breast Neoplasms 29037220 circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a. lncRNA target hsa-mir-124 Cardiovascular Diseases [unspecific] 29042195 Circular RNA WDR77 target FGF-2 to regulate vascular smooth muscle cells proliferation and migration by sponging miR-124. lncRNA target hsa-mir-34a Gastric Neoplasms 29080815 Knockdown of long non-coding RNA HOTAIR inhibits cisplatin resistance of gastric cancer cells through inhibiting the PI3K/Akt and Wnt/¦Â-catenin signaling pathways by up-regulating miR-34a. lncRNA target hsa-mir-939 Colorectal Carcinoma 29081216 Long Noncoding RNA HEIH Promotes Colorectal Cancer Tumorigenesis via Counteracting miR-939?Mediated Transcriptional Repression of Bcl-xL. lncRNA target hsa-mir-200c Lung Fibrosis 29113749 Long non-coding RNA-ATB promotes EMT during silica-induced pulmonary fibrosis by competitively binding miR-200c. lncRNA target hsa-mir-184 "Squamous Cell Carcinoma, Oral" 29125238 LncRNA UCA1 promotes proliferation and cisplatin resistance of oral squamous cell carcinoma by sunppressing miR-184 expression. lncRNA target hsa-mir-9 Glioma 29137410 LINC00461 knockdown decreased expression levels of microRNA miR-9 and flanking genes MEF2C and TMEM161B lncRNA target hsa-mir-195 Wilms Tumor 29159834 LINC00473 as an oncogene is up-regulated to participate into the molecular pathogenesis of Wilms tumour via miR-195/IKK¦Á lncRNA target hsa-mir-613 "Carcinoma, Lung, Non-Small-Cell" 29187267 Long Noncoding RNA (lncRNA) HOTAIR Affects Tumorigenesis and Metastasis of Non-Small Cell Lung Cancer by Upregulating miR-613. lncRNA target hsa-mir-215 Colorectal Carcinoma 29187907 Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression lncRNA target hsa-mir-34a Cervical Neoplasms 29218240 "The long noncoding RNA LINC00473, a target of microRNA 34a, promotes tumorigenesis by inhibiting ILF2 degradation in cervical cancer" lncRNA target hsa-mir-32 Pancreatic Neoplasms 29225772 Long non-coding RNA GAS5 suppresses pancreatic cancer metastasis through modulating miR-32-5p/PTEN axis lncRNA target hsa-mir-125b Sepsis 29227823 "MALAT1 aggravates cardiac inflammation and dysfunction in sepsis, which is achieved via interaction with miR-125b and p38 MAPK/NF¦ÊB" lncRNA target hsa-mir-21 "Stroke, Ischemic" 29238035 "our data uncovers a novel mechanism of lncRNA MEG3 as a ceRNA by targeting miR-21/PDCD4 signaling pathway in regulating ischemic neuronal death, which may help develop new strategies for the therapeutic interventions in cerebral ischemic stroke" lncRNA target hsa-mir-373 Glioma 29310118 Long Non-Coding RNA HOXA-AS2 Regulates Malignant Glioma Behaviors and Vasculogenic Mimicry Formation via the MiR-373/EGFR Axis lncRNA target hsa-mir-21 Osteosarcoma 29323740 "Long non-coding RNA ASBEL promotes osteosarcoma cell proliferation, migration and invasion by regulating microRNA-21" lncRNA target hsa-mir-27a Diabetic Nephropathy 29334763 Long Noncoding RNA LINC01619 Regulates MicroRNA-27a/Forkhead Box Protein O1 and Endoplasmic Reticulum Stress-Mediated Podocyte Injury in Diabetic Nephropathy lncRNA target hsa-let-7a "Squamous Cell Carcinoma, Esophageal" 29393461 Lin28/microRNA-let-7a promotes metastasis under circumstances of hyperactive Wnt signaling in esophageal squamous cell carcinoma lncRNA target hsa-mir-10a Glioblastoma 29397407 Long non-coding RNA TUSC7 inhibits temozolomide resistance by targeting miR-10a in glioblastoma lncRNA target hsa-mir-196a Lung Fibrosis 29411215 The lncRNA H19 Mediates Pulmonary Fibrosis by Regulating the miR-196a/COL1A1 Axis. lncRNA target hsa-mir-124 Glioma 29412778 TP73-AS1 was specificallyupregulated in brain glioma cell lines and promoted glioma cell growth through targeting miR-124TP73-AS1 was specifically upregulated in brain glioma cell lines and promoted glioma cell growth through targeting miR-124 lncRNA target hsa-mir-23a Hypoxic-Ischemic Encephalopathy 29428721 GAS5 regulated hippocampal neuron function by sponging miR-23a lncRNA target hsa-mir-18a Prostate Neoplasms 29465000 Long non-coding RNA FENDRR reduces prostate cancer malignancy by competitively binding miR-18a-5p with RUNX1. lncRNA target hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 29466052 Long noncoding RNA SNHG1 promotes non-small cell lung cancer progression by up-regulating MTDH via sponging miR-145-5p. lncRNA target hsa-mir-101 Glioblastoma 29479863 Long noncoding RNA MALAT1 knockdown reverses chemoresistance to temozolomide via promoting microRNA-101 in glioblastoma lncRNA target hsa-mir-21 "Carcinoma, Lung" 29503447 "We found that LIN28B overexpression significantly increased the number of CD44+/CD326+ tumor cells, upregulated VEGF-A and miR-21 and promoted tumor angiogenesis and epithelial-to-mesenchymal transition (EMT) accompanied by enhanced AKT phosphorylation and nuclear translocation of c-MYC" lncRNA target hsa-mir-181a "Carcinoma, Skin" 29514220 Long non-coding RNA CASC2 inhibits tumorigenesis via the miR-181a/PLXNC1 axis in melanoma. lncRNA target hsa-mir-145 "Carcinoma, Hepatocellular" 29559320 Long non-coding RNA ROR promotes radioresistance in hepatocelluar carcinoma cells by acting as a ceRNA for microRNA-145 to regulate RAD18 expression lncRNA target hsa-mir-503 Prostate Neoplasms 29571017 Long noncoding RNA SNHG7 accelerates prostate cancer proliferation and cycle progression through cyclin D1 by sponging miR-503. lncRNA target hsa-mir-513c "Carcinoma, Hepatocellular" 29574975 "LncRNA FLVCR1-AS1 acts as miR-513c sponge to modulate cancer cell proliferation, migration, and invasion in hepatocellular carcinoma." lncRNA target hsa-mir-140 "Carcinoma, Cervical" 29604594 LncRNA SNHG20 promotes cell proliferation and invasion via miR-140-5p-ADAM10 axis in cervical cancer. lncRNA target hsa-mir-26b "Carcinoma, Breast" 29620147 lncRNA PVT1 promotes the angiogenesis of vascular endothelial cell by targeting miR?26b to activate CTGF/ANGPT2. lncRNA target hsa-mir-5095 Cholangiocarcinoma 29620172 Long noncoding RNA LINC01296 promotes tumor growth and progression by sponging miR-5095 in human cholangiocarcinoma. lncRNA target hsa-let-7 "Colitis, Ulcerative" 29621481 "H19 lncRNA bound to p53 and microRNAs that inhibit cell proliferation, including microRNA 34a and let-7; H19 lncRNA binding blocked their function, leading to increased expression of genes that promote regeneration of the epithelium" lncRNA target hsa-mir-125a Oral Neoplasms 29635126 The role of long non-coding RNA ANRIL in the carcinogenesis of oral cancer by targeting miR-125a. lncRNA target hsa-mir-758 "Carcinoma, Lung, Non-Small-Cell" 29635134 The long non-coding RNA-DANCR exerts oncogenic functions in non-small cell lung cancer via miR-758-3p. lncRNA target hsa-mir-329 "Carcinoma, Bladder" 29653362 The long noncoding RNA ZFAS1 facilitates bladder cancer tumorigenesis by sponging miR-329. lncRNA target hsa-mir-34c Osteosarcoma 29654165 Knockdown of the oncogene LncRNA NEAT1 restores the availability of miR-34c and improves the sensitivity to cisplatin in osteosarcoma lncRNA target hsa-mir-182 Glioblastoma 29655792 Long non-coding RNA UCA1/miR-182/PFKFB2 axis modulates glioblastoma-associated stromal cells-mediated glycolysis and invasion of glioma cells. lncRNA target hsa-mir-125a "Leukemia, Myeloid, Acute" 29663500 Knockdown of LncRNA-UCA1 suppresses chemoresistance of pediatric AML by inhibiting glycolysis through the microRNA-125a/hexokinase 2 pathway lncRNA target hsa-mir-204 Acute Kidney Failure 29669307 Long non-coding RNA NEAT1 plays an important role in sepsis-induced acute kidney injury by targeting miR-204 and modulating the NF-¦ÊB pathway lncRNA target hsa-mir-100 Pneumonia 29673591 Long noncoding RNA HAGLROS regulates cell apoptosis and autophagy in lipopolysaccharides-induced WI-38?cells via modulating miR-100/NF-¦ÊB axis. lncRNA target hsa-mir-143 "Carcinoma, Bladder" 29674277 Long noncoding RNA FOXD2-AS1 accelerates the gemcitabine-resistance of bladder cancer by sponging miR-143. lncRNA target hsa-mir-1253 Osteosarcoma 29678578 Circular RNA circNASP modulates the malignant behaviors in osteosarcoma via miR-1253/FOXF1 pathway. lncRNA target hsa-mir-34a Colon Neoplasms 29679755 Long non-coding RNA XIST sponges miR-34a to promotes colon cancer progression via Wnt/¦Â-catenin signaling pathway. lncRNA target hsa-mir-125a "Carcinoma, Hepatocellular" 29689270 Mutual suppression of miR-125a and Lin28b in human hepatocellular carcinoma cells. lncRNA target hsa-mir-145 Colon Neoplasms 29690669 "LincRNA-ROR functions as a ceRNA to regulate Oct4, Sox2, and Nanog expression by sponging miR-145 and its effect on biologic characteristics of colonic cancer stem cells" lncRNA target hsa-mir-4302 Lung Neoplasms 29698681 Circular RNA hsa_circRNA_103809 promotes lung cancer progression via facilitating ZNF121-dependent MYC expression by sequestering miR-4302. lncRNA target hsa-mir-142 "Diabetes Mellitus, Type 2" 29704494 "Metformin, a first-line drug for type 2 diabetes mellitus, disrupts the MALAT1/miR-142-3p sponge to decrease invasion and migration in cervical cancer cells." lncRNA target hsa-let-7 Neoplasms [unspecific] 29724816 Modulation of LIN28B/Let-7 Signaling by Propranolol Contributes to Infantile Hemangioma Involution. lncRNA target hsa-mir-124 Invasive Bladder Transitional Cell Carcinoma 29736319 LncRNA MALAT1 promotes tumor growth and metastasis by targeting miR-124/foxq1 in bladder transitional cell carcinoma (BTCC). lncRNA target hsa-mir-185 Colorectal Carcinoma 29737580 Long non-coding RNA FOXD2-AS1 contributes to colorectal?cancer proliferation through its interaction with?microRNA-185-5p. lncRNA target hsa-mir-148a Prostate Neoplasms 29749452 MEF2?activated long non?coding RNA PCGEM1 promotes cell proliferation in hormone?refractory prostate cancer through downregulation of miR?148a. lncRNA target hsa-mir-204 "Carcinoma, Pancreatic" 29753015 LncRNA ZEB2-AS1 promotes pancreatic cancer cell growth and invasion through regulating the miR-204/HMGB1 axis. lncRNA target hsa-mir-30a Gastric Neoplasms 29761936 upregulated expression of linc00483 in gastric cancer acts as a sponge to absorb endogenous tumour suppressor miR-30a-3p lncRNA target hsa-mir-30b Osteosarcoma 29772430 "LncRNA DICER1-AS1 promotes the proliferation, invasion and autophagy of osteosarcoma cells via miR-30b/ATG5." lncRNA target hsa-mir-133 "Carcinoma, Pancreatic" 29772434 The interaction of long non-coding RNA MIAT and miR-133 play a role in the proliferation and metastasis of pancreatic carcinoma. lncRNA target hsa-mir-21 "Leukemia, Myeloid, Chronic" 29772439 Long noncoding RNA MEG3 inhibits proliferation of chronic myeloid leukemia cells by sponging microRNA21. lncRNA target hsa-mir-369 Colorectal Carcinoma 29773344 LncRNA OIP5-AS1 regulates radioresistance by targeting DYRK1A through miR-369-3p in colorectal cancer cells. lncRNA target hsa-mir-141 "Carcinoma, Endometrial" 29775889 LncRNA MIR22HG negatively regulates miR-141-3p to enhance DAPK1 expression and inhibits endometrial carcinoma cells proliferation. lncRNA target hsa-mir-23b "Carcinoma, Hepatocellular" 29778425 LncRNA HOTAIR contributes to the malignancy of hepatocellular carcinoma by enhancing epithelial-mesenchymal transition via sponging miR-23b-3p from ZEB1. lncRNA target hsa-mir-150 Hypertrophy 29786749 Long noncoding RNA myocardial infarction?associated transcript is associated with the microRNA?150?5p/P300 pathway in cardiac hypertrophy. lncRNA target hsa-mir-138 "Carcinoma, Renal Cell" 29789714 Estrogen receptor ¦Â promotes renal cell carcinoma progression via regulating LncRNA HOTAIR-miR-138/200c/204/217 associated CeRNA network. lncRNA target hsa-mir-200c "Carcinoma, Renal Cell" 29789714 Estrogen receptor ¦Â promotes renal cell carcinoma progression via regulating LncRNA HOTAIR-miR-138/200c/204/217 associated CeRNA network. lncRNA target hsa-mir-204 "Carcinoma, Renal Cell" 29789714 Estrogen receptor ¦Â promotes renal cell carcinoma progression via regulating LncRNA HOTAIR-miR-138/200c/204/217 associated CeRNA network. lncRNA target hsa-mir-217 "Carcinoma, Renal Cell" 29789714 Estrogen receptor ¦Â promotes renal cell carcinoma progression via regulating LncRNA HOTAIR-miR-138/200c/204/217 associated CeRNA network. lncRNA target hsa-mir-382 Ovarian Neoplasms 29790629 Long non-coding RNA NEAT1 promoted ovarian cancer cells' metastasis through regulation of miR-382-3p/ROCK1 axial. lncRNA target hsa-mir-873 Lung Neoplasms 29790668 The effects of aberrant expression of LncRNA DGCR5/miR-873-5p/TUSC3 in lung cancer cell progression. lncRNA target hsa-mir-196a "Carcinoma, Breast, Triple Negative" 29793177 Long noncoding RNA GAS5 suppresses triple negative breast cancer progression through inhibition of proliferation and invasion by competitively binding miR-196a-5p. lncRNA target hsa-let-7b Epilepsy 29795132 Long non-coding RNA H19 contributes to apoptosis of hippocampal neurons by inhibiting let-7b in a rat model of temporal lobe epilepsy. lncRNA target hsa-mir-223 Lupus Nephritis 29800915 Long non-coding RNA TUG1 protects renal tubular epithelial cells against injury induced by lipopolysaccharide via regulating microRNA-223. lncRNA target hsa-mir-30a "Carcinoma, Thyroid, Papillary" 29803929 Long noncoding RNA PVT1 enhances the viability and invasion of papillary thyroid carcinoma cells by functioning as ceRNA of microRNA-30a through mediating expression of insulin like growth factor 1 receptor. lncRNA target hsa-mir-449a "Carcinoma, Lung, Non-Small-Cell" 29803931 Long noncoding RNA TP73-AS1 promotes non-small cell lung cancer progression by competitively sponging miR-449a/EZH2. lncRNA target hsa-mir-9 "Carcinoma, Lung, Non-Small-Cell" 29805671 "Regulatory interactions between long noncoding RNA LINC00968 and miR-9-3p in non-small cell lung cancer: A bioinformatic analysis based on miRNA microarray, GEO and TCGA." lncRNA target hsa-mir-29a Colorectal Carcinoma 29807108 Functional role of a long non-coding RNA LIFR-AS1/miR-29a/TNFAIP3 axis in colorectal cancer resistance to pohotodynamic therapy. lncRNA target hsa-mir-137 "Carcinoma, Lung, Non-Small-Cell" 29812958 Knockdown of LncRNA-XIST Suppresses Proliferation and TGF-¦Â1-Induced EMT in NSCLC Through the Notch-1 Pathway by Regulation of miR-137. lncRNA target hsa-mir-129 Lung Neoplasms 29857296 "LncRNA NNT-AS1 promotes the proliferation, and invasion of lung cancer cells via regulating miR-129-5p expression." lncRNA target hsa-mir-142 Osteosarcoma 29864904 Knockdown of long non-coding RNA TP73-AS1 inhibits osteosarcoma cell proliferation and invasion through sponging miR-142. lncRNA target hsa-mir-124 Myocardial Infarction 29864957 TUG1 alleviates hypoxia injury by targeting miR-124 in H9c2 cells. lncRNA target hsa-mir-610 Multiple Myeloma 29864963 Long non-coding RNA FEZF1-AS1 promotes cell growth in multiple myeloma via miR-610/Akt3 axis. lncRNA target hsa-mir-211 "Carcinoma, Ovarian" 29874124 miR-211 sponges lncRNA MALAT1 to suppress tumor growth and progression through inhibiting PHF19 in ovarian carcinoma. lncRNA target hsa-mir-137 "Carcinoma, Renal Cell" 29874202 Long Noncoding RNA Small Nucleolar RNA Host Gene 1 (SNHG1) Promotes Renal Cell Carcinoma Progression and Metastasis by Negatively Regulating miR-137. lncRNA target hsa-mir-6873 Chronic Hepatitis B 29888838 regression analysis of gene expression revealed a strong positive correlation between hsa_circ_0000650 and TGF¦Â2 and a negative correlation between hsa_circ_0000650 and miR-6873-3p lncRNA target hsa-mir-30 Cardiac Fibrosis 29889825 Long Noncoding RNA (lncRNA) n379519 Promotes Cardiac Fibrosis in Post-Infarct Myocardium by Targeting miR-30. lncRNA target hsa-mir-1245 Lung Neoplasms 29891014 Hsa_circ_0046264 up-regulated BRCA2 to suppress lung cancer through targeting hsa-miR-1245. lncRNA target hsa-mir-4695 Osteosarcoma 29901121 Long noncoding RNA AFAP1?AS1 enhances cell proliferation and invasion in osteosarcoma through regulating miR?4695?5p/TCF4?¦Â?catenin signaling. lncRNA target hsa-mir-122 Metabolic Syndrome 29922126 "Those include the HOTAIR and MIAT lncRNAs and their targets, such as miR-122, -150, -155, -182, -197, -375, -608 and HLA-DRA" lncRNA target hsa-mir-150 Metabolic Syndrome 29922126 "Those include the HOTAIR and MIAT lncRNAs and their targets, such as miR-122, -150, -155, -182, -197, -375, -608 and HLA-DRA" lncRNA target hsa-mir-155 Metabolic Syndrome 29922126 "Those include the HOTAIR and MIAT lncRNAs and their targets, such as miR-122, -150, -155, -182, -197, -375, -608 and HLA-DRA" lncRNA target hsa-mir-182 Metabolic Syndrome 29922126 "Those include the HOTAIR and MIAT lncRNAs and their targets, such as miR-122, -150, -155, -182, -197, -375, -608 and HLA-DRA" lncRNA target hsa-mir-197 Metabolic Syndrome 29922126 "Those include the HOTAIR and MIAT lncRNAs and their targets, such as miR-122, -150, -155, -182, -197, -375, -608 and HLA-DRA" lncRNA target hsa-mir-375 Metabolic Syndrome 29922126 "Those include the HOTAIR and MIAT lncRNAs and their targets, such as miR-122, -150, -155, -182, -197, -375, -608 and HLA-DRA" lncRNA target hsa-mir-608 Metabolic Syndrome 29922126 "Those include the HOTAIR and MIAT lncRNAs and their targets, such as miR-122, -150, -155, -182, -197, -375, -608 and HLA-DRA" lncRNA target hsa-mir-21 Colorectal Carcinoma 29928882 CircRNA circ_0026344 as a prognostic biomarker suppresses colorectal cancer progression via microRNA-21 and microRNA-31. lncRNA target hsa-mir-31 Colorectal Carcinoma 29928882 CircRNA circ_0026344 as a prognostic biomarker suppresses colorectal cancer progression via microRNA-21 and microRNA-31. lncRNA target hsa-mir-378a "Carcinoma, Pancreatic" 29930719 this circRNA was most likely to regulate the expression of miR-378a-3p lncRNA target hsa-mir-375 "Adenocarcinoma, Lung" 29932500 "We built a network of hsa_circ_0000792-targeted miRNA gene interactions, including miR-375 and the corresponding messenger RNAs" lncRNA target hsa-mir-324 Alzheimer Disease 29956723 Regulatory effects of the long non?coding RNA RP11?543N12.1 and microRNA?324?3p axis on the neuronal apoptosis induced by the inflammatory reactions of microglia. lncRNA target hsa-mir-4310 Colon Neoplasms 29956772 LncRNA CASC15 promotes colon cancer cell proliferation and metastasis by regulating the miR?4310/LGR5/Wnt/¦Â?catenin signaling pathway. lncRNA target hsa-mir-125b Sepsis 29962507 "Expression of the Long Intergenic Non-Coding RNA (lincRNA) of the NED25 Gene Modulates the microRNA-125b, STAT3, Nitric Oxide, and Procalcitonin Signaling Pathways in Patients with Sepsis." lncRNA target hsa-mir-5003 Gastric Neoplasms 29991048 Long Non-Coding RNA RP11-789C1.1 Suppresses Epithelial to Mesenchymal Transition in Gastric Cancer Through the RP11-789C1.1/MiR-5003/E-Cadherin Axis. lncRNA target hsa-mir-199a "Carcinoma, Breast" 30001527 Linc00518 Contributes to Multidrug Resistance Through Regulating the MiR-199a/MRP1 Axis in Breast Cancer. lncRNA target hsa-mir-23a "Carcinoma, Breast" 30007957 Effect of the LncRNA GAS5-MiR-23a-ATG3 Axis in Regulating Autophagy in Patients with Breast Cancer. lncRNA target hsa-mir-518d "Carcinoma, Cervical" 30007986 "CircRNA8924 Promotes Cervical Cancer Cell Proliferation, Migration and Invasion by Competitively Binding to MiR-518d-5p /519-5p Family and Modulating the Expression of CBX8." lncRNA target hsa-mir-519 "Carcinoma, Cervical" 30007986 "CircRNA8924 Promotes Cervical Cancer Cell Proliferation, Migration and Invasion by Competitively Binding to MiR-518d-5p /519-5p Family and Modulating the Expression of CBX8." lncRNA target hsa-mir-874 Sepsis 30021355 LncRNA H19 functions as an Aquaporin 1 competitive endogenous RNA to regulate microRNA-874 expression in LPS sepsis. lncRNA target hsa-mir-182 "Carcinoma, Thyroid" 30021359 LncRNA MEG3 enhances 131I sensitivity in thyroid carcinoma via sponging miR-182. lncRNA target hsa-mir-193a "Adenocarcinoma, Lung" 30036873 The LncRNA NEAT1 Accelerates Lung Adenocarcinoma Deterioration and Binds to Mir-193a-3p as a Competitive Endogenous RNA. lncRNA target hsa-mir-203 Ischemia-Reperfusion Injury 30041794 LncRNA MALAT1 sponges miR-203 to promote inflammation in myocardial ischemia-reperfusion injury. lncRNA target hsa-mir-302 Pituitary Neoplasms 30048990 Lnc-SNHG1 Activates the TGFBR2/SMAD3 and RAB11A/Wnt/¦Â-Catenin Pathway by Sponging MiR-302/372/373/520 in Invasive Pituitary Tumors. lncRNA target hsa-mir-372 Pituitary Neoplasms 30048990 Lnc-SNHG1 Activates the TGFBR2/SMAD3 and RAB11A/Wnt/¦Â-Catenin Pathway by Sponging MiR-302/372/373/520 in Invasive Pituitary Tumors. lncRNA target hsa-mir-373 Pituitary Neoplasms 30048990 Lnc-SNHG1 Activates the TGFBR2/SMAD3 and RAB11A/Wnt/¦Â-Catenin Pathway by Sponging MiR-302/372/373/520 in Invasive Pituitary Tumors. lncRNA target hsa-mir-520 Pituitary Neoplasms 30048990 Lnc-SNHG1 Activates the TGFBR2/SMAD3 and RAB11A/Wnt/¦Â-Catenin Pathway by Sponging MiR-302/372/373/520 in Invasive Pituitary Tumors. lncRNA target hsa-mir-132 Glioma 30053878 Knockdown of long non-coding RNA NEAT1 inhibits c cell migration and invasion via modulation of SOX2 targeted by miR-132. lncRNA target hsa-mir-637 Hirschsprung Disease 30062828 Long non-coding RNA FAL1 functions as a ceRNA to antagonize the effect of miR-637 on the down-regulation of AKT1 in Hirschsprung's disease. lncRNA target hsa-mir-124 "Squamous Cell Carcinoma, Oral" 30078268 Circular RNA circHIPK3 acts as the sponge of microRNA-124 to promote human oral squamous cell carcinoma cells proliferation lncRNA target hsa-mir-155 "Carcinoma, Hepatocellular" 30091314 XIST Induced by JPX Suppresses Hepatocellular Carcinoma by Sponging miR-155-5p. lncRNA target hsa-mir-219a Osteosarcoma 30099814 "TUG1 accelerated osteosarcoma proliferation, migration, and invasion by competitively sponging miR-219a-5p, leading to upregulation of Phosphatidylinositol-4, 5-Bisphosphate 3-Kinase Catalytic Subunit Alpha and activation of the protein kinase B (AKT) signaling pathway" lncRNA target hsa-mir-454 "Adenocarcinoma, Lung" 30099826 LncRNA HOXA11-AS drives cisplatin resistance of human LUAD cells via modulating miR-454-3p/Stat3. lncRNA target hsa-mir-126 Melanoma 30104884 LINC00888 promoted tumorigenicity of melanoma via miR-126/CRK signaling axis. lncRNA target hsa-mir-140 Multiple Myeloma 30121664 Knockdown of Linc00515 Inhibits Multiple Myeloma Autophagy and Chemoresistance by Upregulating miR-140-5p and Downregulating ATG14. lncRNA target hsa-mir-15a Colorectal Carcinoma 30126852 LINC00473 promotes the Taxol resistance via miR-15a in colorectal cancer. lncRNA target hsa-mir-22 Sepsis 30130540 LncRNA HOX transcript antisense RNA accelerated kidney injury induced by urine-derived sepsis through the miR-22/high mobility group box 1 pathway. lncRNA target hsa-mir-181a Multiple Myeloma 30134227 Long Non-Coding RNA MEG3 Functions as a Competing Endogenous RNA to Regulate HOXA11 Expression by Sponging miR-181a in Multiple Myeloma. lncRNA target hsa-mir-593 "Carcinoma, Breast" 30139516 Downregulation of hsa_circ_0007534 suppresses breast cancer cell proliferation and invasion by targeting miR-593/MUC19 signal pathway. lncRNA target hsa-mir-185 Melanoma 30144501 Long non-coding RNA UCA1 targets miR-185-5p and regulates cell mobility by affecting epithelial-mesenchymal transition in melanoma via Wnt/¦Â-catenin signaling pathway. lncRNA target hsa-mir-134 Atherosclerosis 30158376 LncRNA DIGIT Accelerates Tube Formation of Vascular Endothelial Cells by Sponging miR-134. lncRNA target hsa-mir-120 Thrombosis 30171660 "LncRNA WTAPP1 promotes migration and angiogenesis of endothelial progenitor cells via MMP1 through microRNA 3,120 and Akt/PI3K/autophagy pathways." lncRNA target hsa-mir-3 Thrombosis 30171660 "LncRNA WTAPP1 promotes migration and angiogenesis of endothelial progenitor cells via MMP1 through microRNA 3,120 and Akt/PI3K/autophagy pathways." lncRNA target hsa-mir-214 Glioma 30179681 LncRNA LOC728196/miR-513c axis facilitates glioma carcinogenesis by targeting TCF7. lncRNA target hsa-mir-136 Neuropathic Pain 30203524 LINC00657 expedites neuropathic pain development by modulating miR-136/ZEB1 axis in a rat model. lncRNA target hsa-mir-26a Gastric Neoplasms 30205370 miR-26a/HOXC9 Dysregulation Promotes Metastasis and Stem Cell-Like Phenotype of Gastric Cancer. lncRNA target hsa-mir-206 Ovarian Neoplasms 30205383 LncRNA HOTAIR Regulates CCND1 and CCND2 Expression by Sponging miR-206 in Ovarian Cancer. lncRNA target hsa-mir-331 "Carcinoma, Cervical" 30207103 LncRNA XLOC_006390 facilitates cervical cancer tumorigenesis and metastasis as a ceRNA against miR-331-3p and miR-338-3p. lncRNA target hsa-mir-338 "Carcinoma, Cervical" 30207103 LncRNA XLOC_006390 facilitates cervical cancer tumorigenesis and metastasis as a ceRNA against miR-331-3p and miR-338-3p. lncRNA target hsa-mir-214 Ovarian Neoplasms 30207107 Upregulation of long non-coding RNA XIST has anticancer effects on epithelial ovarian cancer cells through inverse downregulation of hsa-miR-214-3p. lncRNA target hsa-mir-143 "Carcinoma, Salivary Adenoid Cystic" 30217729 ADAMTS9-AS2 promotes migration and invasion in SACC by competing with miR-143-3p lncRNA target hsa-mir-107 "Carcinoma, Cervical" 30231238 lncRNA DLG1-AS1 Promotes Cell Proliferation by Competitively Binding with miR-107 and Up-Regulating ZHX1 Expression in Cervical Cancer. lncRNA target hsa-mir-1207 Nasopharyngeal Neoplasms 30243935 Long non-coding RNA 319 facilitates nasopharyngeal carcinoma carcinogenesis through regulation of miR-1207-5p/KLF12 axis. lncRNA target hsa-mir-671 "Carcinoma, Hepatocellular" 30250300 Hypoxia-induced TUFT1 promotes the growth and metastasis of hepatocellular carcinoma by activating the Ca2+/PI3K/AKT pathway. lncRNA target hsa-mir-451 Osteoarthritis 30272288 LncRNA?p21 promotes chondrocyte apoptosis in osteoarthritis by acting as a sponge for miR?451. lncRNA target hsa-mir-144 "Carcinoma, Renal Cell, Clear-Cell" 30278113 Construction and comprehensive analysis of dysregulated long non-coding RNA-associated competing endogenous RNA network in clear cell renal cell carcinoma. lncRNA target hsa-mir-155 "Carcinoma, Renal Cell, Clear-Cell" 30278113 Construction and comprehensive analysis of dysregulated long non-coding RNA-associated competing endogenous RNA network in clear cell renal cell carcinoma. lncRNA target hsa-mir-21 "Carcinoma, Renal Cell, Clear-Cell" 30278113 Construction and comprehensive analysis of dysregulated long non-coding RNA-associated competing endogenous RNA network in clear cell renal cell carcinoma. lncRNA target hsa-mir-30a "Carcinoma, Hepatocellular" 30278452 Long Non-Coding MALAT1 Functions as a Competing Endogenous RNA to Regulate Vimentin Expression by Sponging miR-30a-5p in Hepatocellular Carcinoma. lncRNA target hsa-mir-130a Glioma 30282068 H19 Functions as a Competing Endogenous RNA to Regulate EMT by Sponging miR-130a-3p in Glioma. lncRNA target hsa-mir-182 "Carcinoma, Bladder" 30285878 Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis. lncRNA target hsa-mir-675 Cataract 30286462 H19 regulates HLECs function through miR-675-mediated CRYAA expression. This finding would provide a novel insight into the pathogenesis of nuclear ARC lncRNA target hsa-mir-34a Neoplasms [unspecific] 30289954 Dual biomarkers long non-coding RNA GAS5 and microRNA-34a co-expression signature in common solid tumors. lncRNA target hsa-mir-330 Cardiovascular Diseases [unspecific] 30297107 The long noncoding RNA XIST protects cardiomyocyte hypertrophy by targeting miR-330-3p. lncRNA target hsa-mir-154 Neuropathic Pain 30335888 LncRNA X inactive specific transcript contributes to neuropathic pain development by sponging miR-154-5p via inducing toll-like receptor 5 in CCI rat models. lncRNA target hsa-mir-20b Ischemia-Reperfusion Injury 30367982 Long noncoding RNA HOTAIR regulates autophagy via the miR-20b-5p/ATG7 axis in hepatic ischemia/reperfusion injury. lncRNA target hsa-mir-129 Neoplasms [unspecific] 30374364 "NEAT1 functions as a scaffold RNA molecule by interacting with EZH2 (a subunit of the polycomb repressive complex) to influence the expression of downstream effectors of EZH2, it also acts as a microRNA (miRNA) sponge to suppress the interactions between miRNAs and target mRNAs, and affects the expression of miR-129 by promoting the DNA methylation of the miR-129 promoter region" lncRNA target hsa-mir-153 Intervertebral Disc Degeneration 30378116 LINC00641 regulates autophagy and intervertebral disc degeneration by acting as a competitive endogenous RNA of miR-153-3p under nutrition deprivation stress. target gene hsa-let-7a-1 Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. target gene hsa-let-7a-2 Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. target gene hsa-let-7a-3 Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. target gene hsa-let-7b Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. target gene hsa-let-7c Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. target gene hsa-let-7d Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. target gene hsa-let-7e Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. target gene hsa-let-7f-1 Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. target gene hsa-let-7f-2 Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. target gene hsa-let-7g Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. target gene hsa-let-7i Lung Neoplasms 15172979 decreased abundance; negatively regulate the RAS gene. target gene hsa-mir-143 Obesity 16195701 "Modified oligonucleotide complementary to miR-143 effectively suppressed adipocyte differentiation by modulation of its putative target ERK5, a protein previously known to be implicated in MAP kinase signaling pathways." target gene hsa-mir-372 Testicular Neoplasms 16564011 A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. target gene hsa-mir-373 Testicular Neoplasms 16564011 A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. target gene hsa-mir-122 "Carcinoma, Hepatocellular" 16777601 inhibite CAT-1 target gene hsa-mir-155 Gastrointestinal Neoplasms 16875667 "Therefore, we concluded that artificial miRNA can depress the expression of PRL-3, and that PRL-3 might be a potential therapeutic target for gastric cancer peritoneal metastasis." target gene hsa-mir-20a Breast Neoplasms 17011485 "TGF-b-2 receptor is expressed in the epithelium of breast cancer and can be regulated by miR-20a, which is down- regulated in breast cancer." target gene hsa-mir-127 Neoplasms [unspecific] 17012848 "For example, mir-127, which is generally expressed in normal cells but absent in cancer cells, was markedly induced after treatment. Intriguingly, a predicted target of mir-127, BCL6, was translationally downregulated after treatment." target gene hsa-mir-146a Thyroid Neoplasms 17012848 "Mir-221, mir-22 and mir-146 are significantly upregulated in this disease, whereas the expression of their predicted target gene KIT is lost, concurrently with the miRNA upregulation." target gene hsa-mir-146b Thyroid Neoplasms 17012848 "Mir-221, mir-22 and mir-146 are significantly upregulated in this disease, whereas the expression of their predicted target gene KIT is lost, concurrently with the miRNA upregulation." target gene hsa-mir-22 Thyroid Neoplasms 17012848 "Mir-221, mir-22 and mir-146 are significantly upregulated in this disease, whereas the expression of their predicted target gene KIT is lost, concurrently with the miRNA upregulation." target gene hsa-mir-221 Thyroid Neoplasms 17012848 "Mir-221, mir-22 and mir-146 are significantly upregulated in this disease, whereas the expression of their predicted target gene KIT is lost, concurrently with the miRNA upregulation." target gene hsa-mir-19a "Carcinoma, Hepatocellular" 17188425 miRNA-19a/b activates PI3K by blocking expression of the tumor suppressor PTEN. target gene hsa-mir-19b-1 "Carcinoma, Hepatocellular" 17188425 miRNA-19a/b activates PI3K by blocking expression of the tumor suppressor PTEN. target gene hsa-mir-19b-2 "Carcinoma, Hepatocellular" 17188425 miRNA-19a/b activates PI3K by blocking expression of the tumor suppressor PTEN. target gene hsa-mir-200a "Carcinoma, Hepatocellular" 17188425 "Integration at FRA1A may silence expression of miRNA-200a, which is known to be decreased in HCC compared to nontumor [59] and [65]. Since most miRNAs suppress their target proteins, and miRNA-200a is known to regulate the expression of RAB30, a member of" target gene hsa-mir-224 Hepatitis C Virus Infection 17188425 "miRNA-224 regulates PDGFR expression, and decreases as disease progresses from chronic hepatitis to cirrhosis [59], suggesting that miRNA normally suppresses PDGFR in the liver until HBV integration and genetic instability upsets this balance. miRNA-224 a" target gene hsa-let-7c Leiomyoma 17243163 HMGA2 was identified as one of target genes of the let-7 family of miRNAs and has been found to be suppressed by let-7 in vitro. target gene hsa-mir-206 Breast Neoplasms 17312270 The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines. target gene hsa-let-7a-1 Neoplasms [unspecific] 17322030 Disrupting the pairing between let-7 and Hmga2 target gene hsa-let-7a-2 Neoplasms [unspecific] 17322030 Disrupting the pairing between let-7 and Hmga2 target gene hsa-let-7a-3 Neoplasms [unspecific] 17322030 Disrupting the pairing between let-7 and Hmga2 target gene hsa-let-7b Neoplasms [unspecific] 17322030 Disrupting the pairing between let-7 and Hmga2 target gene hsa-let-7c Neoplasms [unspecific] 17322030 Disrupting the pairing between let-7 and Hmga2 target gene hsa-let-7d Neoplasms [unspecific] 17322030 Disrupting the pairing between let-7 and Hmga2 target gene hsa-let-7e Neoplasms [unspecific] 17322030 Disrupting the pairing between let-7 and Hmga2 target gene hsa-let-7f-1 Neoplasms [unspecific] 17322030 Disrupting the pairing between let-7 and Hmga2 target gene hsa-let-7f-2 Neoplasms [unspecific] 17322030 Disrupting the pairing between let-7 and Hmga2 target gene hsa-let-7g Neoplasms [unspecific] 17322030 Disrupting the pairing between let-7 and Hmga2 target gene hsa-let-7i Neoplasms [unspecific] 17322030 Disrupting the pairing between let-7 and Hmga2 target gene hsa-mir-302b Thyroid Neoplasms 17355635 "Genetically PTC is defined by several alterations which cause abnormal activation of the mitogen-activated protein kinase (MAPK) pathway, the most prevalent being point mutations in the intracellular signalling kinase BRAF. Of particular interest in this study is the downregulation of miR-323 and miR-302b in BRAF mutated cell line. miRBASE target database predicted that the BRAF transcript has binding sites for miR-323 and miR-302b to potentially bind and down- regulate BRAF expression." target gene hsa-mir-323a Thyroid Neoplasms 17355635 "Genetically PTC is defined by several alterations which cause abnormal activation of the mitogen-activated protein kinase (MAPK) pathway, the most prevalent being point mutations in the intracellular signalling kinase BRAF. Of particular interest in this study is the downregulation of miR-323 and miR-302b in BRAF mutated cell line. miRBASE target database predicted that the BRAF transcript has binding sites for miR-323 and miR-302b to potentially bind and down- regulate BRAF expression." target gene hsa-mir-122 Hepatitis C Virus Infection 17462786 "Although miRNA regulation of cellular target genes through 3'UTR binding seems to be only negative, the hepatitis C virus (HCV) has creatively made use of the liver-specific and abundantly expressed miR-122 to promote viral replication." target gene hsa-mir-32 Viral Infectious Disease 17462786 "This has been reported for the retrovirus primate foamy virus-1 (PFV-1), which can be targeted by the host miR-32 [150], which was suggested to restrict its infection." target gene hsa-mir-124a Pancreatic Neoplasms 17462994 MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines. target gene hsa-mir-1 Arrhythmia 17516552 "we also designed the microRNA-masking antisense based on the miR-1 and miR-133 target sites in the 3'UTRs of HCN2 and HCN4 and found that these antisense oligodeoxynucleotides markedly enhanced HCN2/HCN4 expression and function, as reflected by increased protein levels of HCN2/HCN4 and If conductance, by removing the repression of HCN2/HCN4 expression induced by endogenous miR-1/miR-133." target gene hsa-mir-133 Arrhythmia 17516552 "we also designed the microRNA-masking antisense based on the miR-1 and miR-133 target sites in the 3'UTRs of HCN2 and HCN4 and found that these antisense oligodeoxynucleotides markedly enhanced HCN2/HCN4 expression and function, as reflected by increased protein levels of HCN2/HCN4 and If conductance, by removing the repression of HCN2/HCN4 expression induced by endogenous miR-1/miR-133." target gene hsa-mir-221 Prostate Neoplasms 17569667 miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1. target gene hsa-mir-222 Prostate Neoplasms 17569667 miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1. target gene hsa-mir-122 "Carcinoma, Hepatocellular" 17616664 "Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma." target gene hsa-mir-125b Alzheimer Disease 17629564 "The main finding was that these ROS-generating neurotoxic metal sulfates also up-regulate a specific set of miRNAs that includes miR-9, miR-125b and miR-128. Notably, these same miRNAs are up-regulated in AD brain." target gene hsa-let-7i Immune System Disease [unspecific] 17660297 These results indicate that let-7i regulates TLR4 expression in cholangiocytes and contributes to epithelial immune responses against C. parvum infection. target gene hsa-mir-155 Hypertension 17668390 "Since hsa-miR-155 is on chromosome 21, we hypothesize that the observed lower blood pressure in trisomy 21 is partially caused by the overexpression of hsa-miR-155 leading to allele-specific underexpression of AGTR1." target gene hsa-mir-103a-1 Myotonic Muscular Dystrophy 17697356 "These results support a role for miRNAs in DM1 pathogenesis, and, in particular, highlight mir-107 and mir-103 as attractive candidates for binding to DMPK." target gene hsa-mir-103a-2 Myotonic Muscular Dystrophy 17697356 "These results support a role for miRNAs in DM1 pathogenesis, and, in particular, highlight mir-107 and mir-103 as attractive candidates for binding to DMPK." target gene hsa-mir-107 Myotonic Muscular Dystrophy 17697356 "These results support a role for miRNAs in DM1 pathogenesis, and, in particular, highlight mir-107 and mir-103 as attractive candidates for binding to DMPK." target gene hsa-mir-145 Colon Neoplasms 17827156 Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. target gene hsa-mir-17 Neuroblastoma 17894887 miRNAs from the miR-17-92 cluster modulate tumor formation and function as oncogenes by influencing the translation of E2F1 mRNA. target gene hsa-mir-18 Neuroblastoma 17894887 miRNAs from the miR-17-92 cluster modulate tumor formation and function as oncogenes by influencing the translation of E2F1 mRNA. target gene hsa-mir-19a Neuroblastoma 17894887 miRNAs from the miR-17-92 cluster modulate tumor formation and function as oncogenes by influencing the translation of E2F1 mRNA. target gene hsa-mir-19b-1 Neuroblastoma 17894887 miRNAs from the miR-17-92 cluster modulate tumor formation and function as oncogenes by influencing the translation of E2F1 mRNA. target gene hsa-mir-20a Neuroblastoma 17894887 miRNAs from the miR-17-92 cluster modulate tumor formation and function as oncogenes by influencing the translation of E2F1 mRNA. target gene hsa-mir-34a Neuroblastoma 17894887 miR-34a acts as a suppressor of neuroblastoma tumorigenesis by targeting the mRNA encoding E2F3 and reducing E2F3 protein levels. target gene hsa-mir-92-1 Neuroblastoma 17894887 miRNAs from the miR-17-92 cluster modulate tumor formation and function as oncogenes by influencing the translation of E2F1 mRNA. target gene hsa-mir-125b Human Immunodeficiency Virus Infection 17906637 "We have found that the 3' ends of HIV-1 messenger RNAs are targeted by a cluster of cellular miRNAs including miR-28, miR-125b, miR-150, miR-223 and miR-382, which are enriched in resting CD4+ T cells as compared to activated CD4+ T cells." target gene hsa-mir-150 Human Immunodeficiency Virus Infection 17906637 "We have found that the 3' ends of HIV-1 messenger RNAs are targeted by a cluster of cellular miRNAs including miR-28, miR-125b, miR-150, miR-223 and miR-382, which are enriched in resting CD4+ T cells as compared to activated CD4+ T cells." target gene hsa-mir-223 Human Immunodeficiency Virus Infection 17906637 "We have found that the 3' ends of HIV-1 messenger RNAs are targeted by a cluster of cellular miRNAs including miR-28, miR-125b, miR-150, miR-223 and miR-382, which are enriched in resting CD4+ T cells as compared to activated CD4+ T cells." target gene hsa-mir-28 Human Immunodeficiency Virus Infection 17906637 "We have found that the 3' ends of HIV-1 messenger RNAs are targeted by a cluster of cellular miRNAs including miR-28, miR-125b, miR-150, miR-223 and miR-382, which are enriched in resting CD4+ T cells as compared to activated CD4+ T cells." target gene hsa-mir-382 Human Immunodeficiency Virus Infection 17906637 "We have found that the 3' ends of HIV-1 messenger RNAs are targeted by a cluster of cellular miRNAs including miR-28, miR-125b, miR-150, miR-223 and miR-382, which are enriched in resting CD4+ T cells as compared to activated CD4+ T cells." target gene hsa-mir-155 Pancreatic Neoplasms 17911264 "Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development." target gene hsa-mir-130a Neoplasms [unspecific] 17957028 "From these data, we conclude that miR-130a is a regulator of the angiogenic phenotype of vascular ECs largely through its ability to modulate the expression of GAX and HOXA5." target gene hsa-mir-133a-1 Arrhythmia 17965831 miR-133 was shown to inhibit the expression of ERG (ether-a-go-go-related gene) and cause depression of the potassium channel I(Kr). This inhibition contributed to long QT syndrome and arrhythmia in a diabetic rat model. target gene hsa-mir-133a-1 Long QT Syndrome 17965831 miR-133 was shown to inhibit the expression of ERG (ether-a-go-go-related gene) and cause depression of the potassium channel I(Kr). This inhibition contributed to long QT syndrome and arrhythmia in a diabetic rat model. target gene hsa-mir-133a-2 Arrhythmia 17965831 miR-133 was shown to inhibit the expression of ERG (ether-a-go-go-related gene) and cause depression of the potassium channel I(Kr). This inhibition contributed to long QT syndrome and arrhythmia in a diabetic rat model. target gene hsa-mir-133a-2 Long QT Syndrome 17965831 miR-133 was shown to inhibit the expression of ERG (ether-a-go-go-related gene) and cause depression of the potassium channel I(Kr). This inhibition contributed to long QT syndrome and arrhythmia in a diabetic rat model. target gene hsa-mir-181b Neoplasms [unspecific] 17965831 "Many miRNAs are located at chromosomal break points or fragile sites associated with cancer. Indeed miR-29a and miR-29b are associated with the fragile site FRA7H. In addition, miR-29b along with miR-181b may target the oncogene TCL1 in CLL patients [163]" target gene hsa-mir-21 Brain Neoplasms 17965831 "The overexpression of miR-21 was recognized in malignant brain tumours, and knockdown of this miRNA in cultured glioblastoma cells resulted in caspase activation and apoptosis. The tumour suppressor tropomyosin 1 (TPM1) was demonstrated to be a target for miR-21, explaining why inhibition of miR-21 results in reduced tumour growth." target gene hsa-mir-29a Neoplasms [unspecific] 17965831 "Many miRNAs are located at chromosomal break points or fragile sites associated with cancer. Indeed miR-29a and miR-29b are associated with the fragile site FRA7H. In addition, miR-29b along with miR-181b may target the oncogene TCL1 in CLL patients [163], while miR-29b reduced Mcl-1 protein and rendered cholangiocarcinoma cells more susceptible to apoptosis." target gene hsa-mir-29b-1 Neoplasms [unspecific] 17965831 "Many miRNAs are located at chromosomal break points or fragile sites associated with cancer. Indeed miR-29a and miR-29b are associated with the fragile site FRA7H. In addition, miR-29b along with miR-181b may target the oncogene TCL1 in CLL patients [163], while miR-29b reduced Mcl-1 protein and rendered cholangiocarcinoma cells more susceptible to apoptosis." target gene hsa-mir-29b-2 Neoplasms [unspecific] 17965831 "Many miRNAs are located at chromosomal break points or fragile sites associated with cancer. Indeed miR-29a and miR-29b are associated with the fragile site FRA7H. In addition, miR-29b along with miR-181b may target the oncogene TCL1 in CLL patients [163]" target gene hsa-mir-34a Neuroblastoma 17965831 "miR-34a induces apoptosis in neuroblastoma cells, possibly by targeting the transcription factor E2F3. This p53-induced up-regulation of miR-34a results in an enhanced reduction in cell proliferation, strongly suggesting that miR-34a reinforces the tumour suppressor function of p53." target gene hsa-mir-134 Fragile X Syndrome 17982590 spine morphology in patients with Fragile-X mental retardation syndrome (FXS) is not dissimilar from the spine structure observed on miR-134 overexpression or in neurons deficient for the miR-134 target Limk1 target gene hsa-let-7a-1 Neoplasms [unspecific] 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes target gene hsa-let-7a-2 Neoplasms [unspecific] 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes target gene hsa-let-7a-3 Neoplasms [unspecific] 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes target gene hsa-let-7b Neoplasms [unspecific] 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes target gene hsa-let-7c Neoplasms [unspecific] 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes target gene hsa-let-7d Neoplasms [unspecific] 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes target gene hsa-let-7e Neoplasms [unspecific] 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes target gene hsa-let-7f-1 Neoplasms [unspecific] 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes target gene hsa-let-7f-2 Neoplasms [unspecific] 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes target gene hsa-let-7g Neoplasms [unspecific] 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes target gene hsa-let-7i Neoplasms [unspecific] 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes target gene hsa-mir-372 Neoplasms [unspecific] 17989227 "the related miR-372/373 miRNAs promote tumorigenesis in combination with oncogenic RAS, at least in part by directly inhibiting the tumor suppressor LATS2." target gene hsa-mir-373 Neoplasms [unspecific] 17989227 "the related miR-372/373 miRNAs promote tumorigenesis in combination with oncogenic RAS, at least in part by directly inhibiting the tumor suppressor LATS2." target gene hsa-mir-218 Cervical Neoplasms 17998940 We also show that LAMB3 expression is increased in the presence of the HPV-16 E6 oncogene and this effect is mediated through miR-218. These findings may contribute to a better understanding of the molecular mechanisms involved in cervical carcinogenesis. target gene hsa-let-7c Neoplasms [unspecific] 18006822 "In addition to known genes, siRNAs targeting CDK4, PTGS1, ALG2, CLCN3, IRAK4, and MAP3K8 altered TRAIL-induced caspase-3 activation responses. Introduction of the miRNAs let-7c, mir-10a, mir-144, mir-150, mir-155, and mir-193 also affected the activation of the caspase cascade." target gene hsa-mir-10a Neoplasms [unspecific] 18006822 "In addition to known genes, siRNAs targeting CDK4, PTGS1, ALG2, CLCN3, IRAK4, and MAP3K8 altered TRAIL-induced caspase-3 activation responses. Introduction of the miRNAs let-7c, mir-10a, mir-144, mir-150, mir-155, and mir-193 also affected the activation of the caspase cascade." target gene hsa-mir-144 Neoplasms [unspecific] 18006822 "In addition to known genes, siRNAs targeting CDK4, PTGS1, ALG2, CLCN3, IRAK4, and MAP3K8 altered TRAIL-induced caspase-3 activation responses. Introduction of the miRNAs let-7c, mir-10a, mir-144, mir-150, mir-155, and mir-193 also affected the activation of the caspase cascade." target gene hsa-mir-150 Neoplasms [unspecific] 18006822 "In addition to known genes, siRNAs targeting CDK4, PTGS1, ALG2, CLCN3, IRAK4, and MAP3K8 altered TRAIL-induced caspase-3 activation responses. Introduction of the miRNAs let-7c, mir-10a, mir-144, mir-150, mir-155, and mir-193 also affected the activation of the caspase cascade." target gene hsa-mir-155 Neoplasms [unspecific] 18006822 "In addition to known genes, siRNAs targeting CDK4, PTGS1, ALG2, CLCN3, IRAK4, and MAP3K8 altered TRAIL-induced caspase-3 activation responses. Introduction of the miRNAs let-7c, mir-10a, mir-144, mir-150, mir-155, and mir-193 also affected the activation of the caspase cascade." target gene hsa-mir-193 Neoplasms [unspecific] 18006822 "In addition to known genes, siRNAs targeting CDK4, PTGS1, ALG2, CLCN3, IRAK4, and MAP3K8 altered TRAIL-induced caspase-3 activation responses. Introduction of the miRNAs let-7c, mir-10a, mir-144, mir-150, mir-155, and mir-193 also affected the activation of the caspase cascade." target gene hsa-mir-27a Breast Neoplasms 18006846 The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. target gene hsa-let-7b Retinoblastoma 18026111 We experimentally verified our predictions by investigating the result of let-7b downregulation in retinoblastoma using quantitative reverse transcriptase (RT)-PCR and microarray profiling: some of our verified let-7b targets include CDC25A and BCL7A. target gene hsa-mir-221 Vascular Disease [unspecific] 18068232 "miR-221 and miR-222 block endothelial cell migration, proliferation and angiogenesis in vitro by targeting the stem cell factor receptor c-Kit and indirectly regulating expression of endothelial nitric oxide synthase." target gene hsa-mir-222 Vascular Disease [unspecific] 18068232 "miR-221 and miR-222 block endothelial cell migration, proliferation and angiogenesis in vitro by targeting the stem cell factor receptor c-Kit and indirectly regulating expression of endothelial nitric oxide synthase." target gene hsa-mir-378 Neoplasms [unspecific] 18077375 "Our results suggest that miR-378 transfection enhanced cell survival, tumor growth, and angiogenesis through repression of the expression of two tumor suppressors, Sufu and Fus-1." target gene hsa-mir-101 Neoplasms [unspecific] 18096665 "The most up-regulated miR-196b and its precursors are highly expressed in the skin and showed similar tissue-specific expression patterns after treatment, indicating a common pattern of regulation by E(2). MiR-196b was shown to fine-tune the expression of its target gene Hoxb8a after treatment in whole-body homogenates." target gene hsa-mir-146a Prostate Neoplasms 18174313 "Given that ROCK1 is one of the key kinases for the activation of hyaluronan (HA)-mediated HRPC transformation in vivo and in PC3 cells, mir-146a may function as a tumor-suppressor gene in modulating HA/ROCK1-mediated tumorigenecity in androgen-dependent prostate cancer." target gene hsa-mir-433 Parkinson Disease 18252210 Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. target gene hsa-mir-224 "Carcinoma, Hepatocellular" 18319255 Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target. target gene hsa-mir-106b Gastrointestinal Neoplasms 18328430 "Together, these results suggest that the miR-106b-25 cluster is involved in E2F1 posttranscriptional regulation and may play a key role in the development of TGFbeta resistance in gastric cancer." target gene hsa-mir-21 Neoplasms [unspecific] 18372920 The demonstration that miR-21 promotes cell transformation supports the concept that mir-21 functions as an oncogene by a mechanism that involves translational repression of the tumor suppressor Pdcd4. target gene hsa-mir-141 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. target gene hsa-mir-200a Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. target gene hsa-mir-200b Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. target gene hsa-mir-200c Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. target gene hsa-mir-205 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. target gene hsa-mir-429 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. target gene hsa-let-7b Melanoma 18379589 MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. target gene hsa-let-7c Leiomyoma 18403645 Our findings suggest that the Let-7-mediated repression of HMGA2 mechanism can be an important molecular event in leiomyoma growth. target gene hsa-mir-199a Ovarian Neoplasms 18408758 "Furthermore, we describe for the first time the identification of the microRNA hsa-miR-199a as a regulator of IKKbeta expression. Our study describes the property of ovarian cancer cells to enhance the inflammatory microenvironment as a result of the expression of an active IKKbeta pathway." target gene hsa-let-7a Gastric Neoplasms 18413822 Clinical significance of high mobility group A2 in human gastric cancer and its relationship to let-7 microRNA family. target gene hsa-mir-15b Gastric Neoplasms 18449891 miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. target gene hsa-mir-16-1 Gastric Neoplasms 18449891 miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. target gene hsa-mir-16-2 Gastric Neoplasms 18449891 miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. target gene hsa-mir-1-1 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. target gene hsa-mir-1-2 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. target gene hsa-mir-133a-1 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. target gene hsa-mir-133a-2 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. target gene hsa-mir-133b Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. target gene hsa-mir-16-1 "Lymphoma, Mantle-Cell" 18483394 Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma. target gene hsa-mir-203 "Squamous Cell Carcinoma, Head and Neck" 18483491 "we have shown that miR-203 can regulate DeltaNp63 levels upon genotoxic damage in head and neck squamous cell carcinoma cells, thus controlling cell survival." target gene hsa-mir-17 Neuroblastoma 18493594 Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM target gene hsa-mir-34a Neuroblastoma 18504438 The MYCN oncogene is a direct target of miR-34a. target gene hsa-mir-34a Neuroblastoma 18505919 A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene. target gene hsa-mir-106a Colon Neoplasms 18521848 Deregulated expression of miR-106a predicts survival in human colon cancer patients. target gene hsa-mir-17 Colon Neoplasms 18521848 Deregulated expression of miR-106a predicts survival in human colon cancer patients. target gene hsa-mir-221 Vascular Disease [unspecific] 18550634 "In contrast, miR-221 and miR-222 inhibit endothelial cell migration, proliferation, and angiogenesis in vitro by targeting the stem cell factor receptor c-kit and indirectly regulating endothelial nitric oxide synthase expression." target gene hsa-mir-222 Vascular Disease [unspecific] 18550634 "In contrast, miR-221 and miR-222 inhibit endothelial cell migration, proliferation, and angiogenesis in vitro by targeting the stem cell factor receptor c-kit and indirectly regulating endothelial nitric oxide synthase expression." target gene hsa-mir-21 Glioma 18591254 MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. target gene hsa-mir-206 Breast Neoplasms 18593897 miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer. target gene hsa-mir-20a Leukemia 18596985 "Here we report, for the first time, that LRF is post-transcriptionally regulated by miR-20a. Using a gene reporter assay, direct interaction of miR-20a with the LRF 3'UTR is demonstrated." target gene hsa-mir-124-1 Medulloblastoma 18607543 miR-124: regulates cyclin dependent kinase 6 target gene hsa-mir-124-2 Medulloblastoma 18607543 miR-124: regulates cyclin dependent kinase 6 target gene hsa-mir-124-3 Medulloblastoma 18607543 miR-124: regulates cyclin dependent kinase 6 target gene hsa-mir-27a Neoplasms [unspecific] 18619946 miR-27a: miR-27a and miR-451 regulate expression of MDR1/P-glycoprotein target gene hsa-mir-451a Neoplasms [unspecific] 18619946 miR-451: miR-27a and miR-451 regulate expression of MDR1/P-glycoprotein target gene hsa-mir-135a-1 Colorectal Carcinoma 18632633 miR-135a: miR-135 family: Regulation of the adenomatous polyposis coli gene target gene hsa-mir-135a-2 Colorectal Carcinoma 18632633 miR-135a: miR-135 family: Regulation of the adenomatous polyposis coli gene target gene hsa-mir-135b Colorectal Carcinoma 18632633 miR-135b: miR-135 family: Regulation of the adenomatous polyposis coli gene target gene hsa-mir-196b Neoplasms [unspecific] 18663355 miR-196: MicroRNA-196a targets annexin A1: a microRNA-mediated mechanism of annexin A1 downregulation in cancers target gene hsa-let-7a-1 Melanoma 18679415 let-7a: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma target gene hsa-let-7a-2 Melanoma 18679415 let-7a: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma target gene hsa-let-7a-3 Melanoma 18679415 let-7a: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma target gene hsa-let-7b Melanoma 18679415 let-7b: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma target gene hsa-let-7c Melanoma 18679415 let-7c: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma target gene hsa-let-7d Melanoma 18679415 let-7d: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma target gene hsa-let-7e Melanoma 18679415 let-7e: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma target gene hsa-let-7f-1 Melanoma 18679415 let-7f: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma target gene hsa-let-7f-2 Melanoma 18679415 let-7f: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma target gene hsa-let-7g Melanoma 18679415 let-7g: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma target gene hsa-let-7i Melanoma 18679415 let-7i: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma target gene hsa-mir-122 "Carcinoma, Hepatocellular" 18692484 "miR-122 targets an anti-apoptotic gene, Bcl-w, in human hepatocellular carcinoma cell lines." target gene hsa-mir-17 Breast Neoplasms 18695042 A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. target gene hsa-mir-20a Breast Neoplasms 18695042 A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. target gene hsa-mir-181a Immune System Disease [unspecific] 18701320 "In addition to facilitating cell fate decisions of immune cells (e.g. miR-181a and miR-223), miRs also regulate central elements of the adaptive immune response such as antigen presentation (e.g. miR-155) and T cell receptor signaling (mir-181a)." target gene hsa-mir-221 Breast Neoplasms 18708351 miR-221: MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1 target gene hsa-mir-222 Breast Neoplasms 18708351 miR-222: MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1 target gene hsa-mir-34a Neoplasms [unspecific] 18755897 "Finally, miR-34a itself is a transcriptional target of p53, suggesting a positive feedback loop between p53 and miR-34a. Thus, miR-34a functions as a tumor suppressor, in part, through a SIRT1-p53 pathway." target gene hsa-mir-125b Medulloblastoma 18756266 "Specifically, we identify miR-125b and miR-326 as suppressors of the pathway activator Smoothened together with miR-324-5p, which also targets the downstream transcription factor Gli1." target gene hsa-mir-324 Medulloblastoma 18756266 "Specifically, we identify miR-125b and miR-326 as suppressors of the pathway activator Smoothened together with miR-324-5p, which also targets the downstream transcription factor Gli1." target gene hsa-mir-326 Medulloblastoma 18756266 "Specifically, we identify miR-125b and miR-326 as suppressors of the pathway activator Smoothened together with miR-324-5p, which also targets the downstream transcription factor Gli1." target gene hsa-let-7a-1 Neoplasms [unspecific] 18758960 Let-7a: Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3 target gene hsa-let-7a-2 Neoplasms [unspecific] 18758960 Let-7a: Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3 target gene hsa-let-7a-3 Neoplasms [unspecific] 18758960 Let-7a: Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3 target gene hsa-mir-223 Inflammation 18791161 "miR-223, which is markedly enhanced by estrogen,regulates LPS-induced IFNgamma, but not iNOS or nitric oxide in splenic lymphocytes. Inhibition of miR-223 activity decreased LPS-induced IFNgamma in splenic lymphocytes from estrogen-treated mice." target gene hsa-mir-221 "Carcinoma, Thyroid, Papillary" 18794255 Microarray analysis showed thousands of genes were directly and indirectly regulated by miR-221 and shifted the gene expression pattern of normal thyroid cells toward PTC. target gene hsa-mir-155 Breast Neoplasms 18794355 These data suggest that miR-155 may play an important role in TGF-beta-induced EMT and cell migration and invasion by targeting RhoA and indicate that it is a potential therapeutic target for breast cancer intervention. target gene hsa-mir-146a Alzheimer Disease 18801740 An NF-kB-sensitive microRNA-146a-mediated inflammatory circuit in Alzheimer's disease and in stressed human brain cells. target gene hsa-mir-128 Glioma 18810376 MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. target gene hsa-mir-215 Glioma 18810376 MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. target gene hsa-mir-15a Leukemia 18818396 "Using a luciferase reporter assay, we found that miR-15a directly binds the 3'-UTR of c-myb mRNA. By transfecting K562 myeloid leukemia cells with a miR-15a mimic, functionality of binding was shown." target gene hsa-mir-192 Inflammation 18835392 "Macrophage inflammatory peptide (MIP)-2 alpha, a chemokine expressed by epithelial cells, was identified as a target of miR-192." target gene hsa-mir-302b "Carcinoma, Embryonal" 18930031 miR-302b: miR-302b maintains stemness of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression target gene hsa-mir-15a Prostate Neoplasms 18931683 The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. target gene hsa-mir-16-1 Prostate Neoplasms 18931683 The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. target gene hsa-mir-16-2 Prostate Neoplasms 18931683 miR-16: The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities target gene hsa-mir-15a Polycystic Kidney Disease 18949056 miR-15a: MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis target gene hsa-mir-296 Brain Neoplasms 18977327 "Growth factor-induced miR-296 contributes significantly to angiogenesis by directly targeting the hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) mRNA, leading to decreased levels of HGS and thereby reducing HGS-mediated degradation of the growth factor receptors VEGFR2 and PDGFRbeta." target gene hsa-mir-128 Glioblastoma 19010882 This showed that miR-128 specifically blocked glioma self-renewal consistent with Bmi-1 down-regulation. target gene hsa-mir-21 Glioblastoma 19013014 miR-21: MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G target gene hsa-mir-223 Leukemia 19017354 "Thus,our results suggest that miR-223 reversibly regulates erythroid and megakaryocytic differentiation of K562 cells via down-modulation of LMO2." target gene hsa-mir-34a Melanoma 19029026 miR-34a: MicroRNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met target gene hsa-mir-143 "Carcinoma, Colon" 19062714 "The increased accumulation of miR-143 inhibits the proliferation of transfected cells, and results in down-regulation of K-ras protein in colorectal carcinoma." target gene hsa-mir-29a Neoplasms [unspecific] 19079265 "miR-29a: miR-29 directly suppress p85 alpha and CDC42, both of which negatively regulate p53" target gene hsa-mir-221 Vascular Disease [unspecific] 19088079 "Our study demonstrates that PDGF signaling, by modulating the expression of miR-221, regulates two critical determinants of the vSMC phenotype; they are SMC gene expression and cell proliferation." target gene hsa-mir-106b "Leukemia, Lymphocytic, Chronic, B-Cell" 19096009 "miR-106b: Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase, Itch for degradation" target gene hsa-mir-15a Head And Neck Neoplasms 19117988 "miR-15a: feed-forward loop: PKCalpha down-regulates miR-15a, which directly inhibits protein synthesis of cyclin E" target gene hsa-mir-221 Melanoma 19126397 miR-221: mir-221 can directly interact with c-kit 3'UTR and inhibit cKit protein translation target gene hsa-mir-1-1 Arrhythmia 19131648 miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2 target gene hsa-mir-1-2 Arrhythmia 19131648 miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2 target gene hsa-mir-101-1 "Carcinoma, Hepatocellular" 19133651 miR-101: MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene target gene hsa-mir-101-2 "Carcinoma, Hepatocellular" 19133651 miR-101: MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene target gene hsa-mir-15b Glioma 19135980 MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells. target gene hsa-mir-143 Colorectal Carcinoma 19137007 miR-143 directly recognize the 3'-untranslated region of KRAS transcripts target gene hsa-mir-155 Immune System Disease [unspecific] 19144316 "Our studies suggest that Foxp3-dependent regulation of miR155 maintains competitive fitness of Treg cell subsets by targeting SOCS1, and they provide experimental support for a proposed role for miRNAs in ensuring the robustness of cellular phenotypes." target gene hsa-mir-15a "Carcinoma, Nasopharyngeal" 19144710 "We found that the tumor suppressor BRCA-1 is a target of miR-15a as well as miR-16, suggesting a miRNA role in NPC pathogenesis." target gene hsa-mir-106b Gastric Neoplasms 19153141 "miR-106b: inhibite p21,p27, and p57" target gene hsa-mir-221 Gastric Neoplasms 19153141 "miR-221: inhibite p21,p27, and p57" target gene hsa-mir-222 Gastric Neoplasms 19153141 "miR-222: inhibite p21,p27, and p57" target gene hsa-mir-25 Gastric Neoplasms 19153141 "miR-25: inhibite p21,p27, and p57" target gene hsa-mir-93 Gastric Neoplasms 19153141 "miR-93: inhibite p21,p27, and p57" target gene hsa-mir-141 Neoplasms [unspecific] 19182522 "miR-141: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2" target gene hsa-mir-200a Neoplasms [unspecific] 19182522 "miR-200a: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2" target gene hsa-mir-200b Neoplasms [unspecific] 19182522 "miR-200b: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2" target gene hsa-mir-200c Neoplasms [unspecific] 19182522 "miR-200c: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2" target gene hsa-mir-429 Neoplasms [unspecific] 19182522 "miR-429: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2" target gene hsa-mir-1-1 Cardiomegaly 19188439 miR-1: MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes target gene hsa-mir-1-2 Cardiomegaly 19188439 miR-1: MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes target gene hsa-mir-182 Melanoma 19188590 miR-182: Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor target gene hsa-mir-18a "Carcinoma, Hepatocellular" 19203451 miR-18: target BTG2 target gene hsa-mir-18b "Carcinoma, Hepatocellular" 19203451 miR-18: target BTG2 target gene hsa-mir-34 Neoplasms [unspecific] 19221490 "Based on this observation, we propose a positive feedback loop, in which p53 induces expression of miR-34a which suppresses SIRT1, increasing p53 activity." target gene hsa-mir-30e Neoplasms [unspecific] 19223510 miR-30e: directly targets Ubc9 target gene hsa-mir-10a Breast Neoplasms 19232136 miR-10a: miR-10a inhibits transcriptional of Hoxd4 target gene hsa-mir-16-1 Breast Neoplasms 19250063 "Two new miR-16 targets: Caprin-1 and HMGA1, proteins implicated in cell proliferation" target gene hsa-mir-16-2 Breast Neoplasms 19250063 "Two new miR-16 targets: Caprin-1 and HMGA1, proteins implicated in cell proliferation" target gene hsa-mir-449a Prostate Neoplasms 19252524 miR-449a targets HDAC-1 and induces growth arrest in prostate cancer. target gene hsa-mir-34b "Leukemia, Myeloid, Acute" 19258499 miR-34b: miR-34b targets cyclic AMP-responsive element binding protein target gene hsa-mir-101-1 Urinary Bladder Cancer 19258506 miR-101: putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2 target gene hsa-mir-101-2 Urinary Bladder Cancer 19258506 miR-101: putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2 target gene hsa-mir-221 Marek Disease 19264608 miR-221: miR-221/222 target p27Kip1 in Marek's disease virus-transformed tumour cell line MSB-1 target gene hsa-mir-222 Marek Disease 19264608 miR-222: miR-221/222 target p27Kip1 in Marek's disease virus-transformed tumour cell line MSB-1 target gene hsa-mir-146b Glioma 19265686 microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs. target gene hsa-mir-328 Breast Neoplasms 19270061 MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells. target gene hsa-mir-205 Breast Neoplasms 19276373 miR-205: a new oncosuppressor regulates HER3 target gene hsa-mir-21 Prostate Neoplasms 19302977 miR-21: MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells target gene hsa-mir-21 "Cardiomyopathy, Hypertrophic" 19336275 miR-21: miR-21 can protect this by targeting PDCD4 target gene hsa-mir-21 Heart Failure 19336275 miR-21: miR-21 can protect this by targeting PDCD4 target gene hsa-mir-21 Myocardial Infarction 19336275 miR-21: miR-21 can protect this by targeting PDCD4 target gene hsa-mir-21 Myocardial Ischemic-Reperfusion Injury 19336275 miR-21: miR-21 can protect this by targeting PDCD4 target gene hsa-mir-532 Melanoma 19336521 "miR-532-5p: miR-532-5p is a regulatory factor of RUNX3, which is down-regulated during melanoma progression" target gene hsa-mir-92a-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 19336759 "miR-92-1: overexpressed, can target the VHL transcript" target gene hsa-mir-145 Breast Neoplasms 19360360 miR-145 inhibits breast cancer cell growth through RTKN. target gene hsa-mir-18a "Adenocarcinoma, Colon" 19372139 The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras target gene hsa-mir-15a Multiple Myeloma 19401561 MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma. target gene hsa-mir-16 Multiple Myeloma 19401561 MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma. target gene hsa-mir-22 Breast Neoplasms 19414598 miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA. target gene hsa-mir-106b Barrett Esophagus 19422085 "MiRs-93 and -106b targeted and inhibited p21, whereas miR-25 targeted and inhibited Bim" target gene hsa-mir-25 Barrett Esophagus 19422085 "MiRs-93 and -106b targeted and inhibited p21, whereas miR-25 targeted and inhibited Bim" target gene hsa-mir-93 Barrett Esophagus 19422085 "MiRs-93 and -106b targeted and inhibited p21, whereas miR-25 targeted and inhibited Bim" target gene hsa-mir-221 Glioma 19424584 Co-suppression of miR-221/222 cluster suppresses human glioma cell growth by targeting p27kip1 in vitro and in vivo. target gene hsa-mir-222 Glioma 19424584 Co-suppression of miR-221/222 cluster suppresses human glioma cell growth by targeting p27kip1 in vitro and in vivo. target gene hsa-mir-124 Medulloblastoma 19427019 miR-124 is frequently down-regulated in medulloblastoma and is a negative regulator of SLC16A1. target gene hsa-mir-143 Hepatoblastoma 19472311 Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression. target gene hsa-mir-222 "Squamous Cell Carcinoma, Tongue" 19487542 MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1(MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cellcarcinoma cell lines. target gene hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 19498445 "miR-15a and miR-16-1 function by targeting multiple oncogenes, including BCL2, MCL1, CCND1, and WNT3A. Down-regulation of these miRNAs has been reported in chronic lymphocytic lymphoma (CLL), pituitary adenomas, and prostate carcinoma." target gene hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 19498445 "miR-15a and miR-16-1 function by targeting multiple oncogenes, including BCL2, MCL1, CCND1, and WNT3A. Down-regulation of these miRNAs has been reported in chronic lymphocytic lymphoma (CLL), pituitary adenomas, and prostate carcinoma." target gene hsa-mir-373 Esophageal Neoplasms 19501585 we demonstrated that the direct inhibition of LATS2 protein was mediated by miR-373 and manipulated the expression of miR-373 to affect esophageal cancer cells growth. target gene hsa-mir-105 Inflammation 19509287 We identified miRNA (miR)-105 as a modulator of TLR-2 protein translation in human gingival keratinocytes. target gene hsa-mir-127 "Lymphoma, Burkitt" 19530237 B cell differentiation in EBV-positive Burkitt Lymphoma is impaired at post-transcriptional level by miRNA altered expression. target gene hsa-mir-34b "Leukemia, Lymphocytic, Chronic, B-Cell" 19536169 miR-34b/miR-34c: a regulator of TCL1 expression in 11q- chronic lymphocytic leukaemia target gene hsa-mir-34c "Leukemia, Lymphocytic, Chronic, B-Cell" 19536169 miR-34b/miR-34c: a regulator of TCL1 expression in 11q- chronic lymphocytic leukaemia target gene hsa-mir-25 Inflammation 19541842 Our study demonstrates that inhibition of miR-25 in cytokine-stimulated ASM cells up-regulates KLF4 expression via a post-transcriptional mechanism. target gene hsa-mir-145 Prostate Neoplasms 19544444 "regulates PDGF-D, which mediate epithelial-mesenchymal transition, adhesion, and invasion, which was associated with the downregulation of ZEB1, ZEB2,and Snail2 expression;" target gene hsa-mir-155 Glioblastoma 19559015 overexpressed; contributes to tumor resistance to VM-26 chemotherapy; targets LRRFIP1; target gene hsa-mir-21 Glioblastoma 19559015 MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme. target gene hsa-mir-21 Human Immunodeficiency Virus Infection 19560422 highly abundant; specifically targets the HIV-1 3'UTR region; Inhibiting miR-29a enhanced HIV-1 viral production and infectivity; specific miR-29a-HIV-1 mRNA interactions enhance viral mRNA association with RISC and P body proteins target gene hsa-mir-200b "Adenocarcinoma, Pancreatic Ductal" 19569050 "regulate EP300, a metastasis suppressor gene; these miRs are related to reduced EP300 mRNA and protein;" target gene hsa-mir-200c "Adenocarcinoma, Pancreatic Ductal" 19569050 "regulate EP300, a metastasis suppressor gene; these miRs are related to reduced EP300 mRNA and protein;" target gene hsa-mir-429 "Adenocarcinoma, Pancreatic Ductal" 19569050 "regulate EP300, a metastasis suppressor gene; these miRs are related to reduced EP300 mRNA and protein;" target gene hsa-mir-125b Breast Neoplasms 19570947 "In conclusion, this study clearly demonstrates that miR-125b post-transcriptionally regulates the CYP24, which serves as a possible mechanism for the high CYP24 expression in cancer tissues." target gene hsa-mir-182 Breast Neoplasms 19574223 "Coordinate Regulate FOXO1; highly expressed; a novel mechanism of FOXO1 regulation, and targeting of FOXO1 by microRNAs may contribute to transformation or maintenance of an oncogenic state in breast cancer cells" target gene hsa-mir-27a Breast Neoplasms 19574223 "Coordinate Regulation of FOXO1 by miR-27a, miR-96, and miR-182 in Breast Cancer Cells." target gene hsa-mir-31 Breast Neoplasms 19574223 "Coordinate Regulate FOXO1; highly expressed; a novel mechanism of FOXO1 regulation, and targeting of FOXO1 by microRNAs may contribute to transformation or maintenance of an oncogenic state in breast cancer cells" target gene hsa-mir-96 Breast Neoplasms 19574223 "Coordinate Regulate FOXO1; highly expressed; a novel mechanism of FOXO1 regulation, and targeting of FOXO1 by microRNAs may contribute to transformation or maintenance of an oncogenic state in breast cancer cells" target gene hsa-mir-27a Prostate Neoplasms 19584056 "decreased in prostate cancer; Regulates ERBB-2 Expression; blocked downstream phosphatidylinositol 3-kinase/AKT signaling, reducing activity of an androgen-stimulated prostate-specific antigen promoter and blocking prostate-specific antigen expression" target gene hsa-mir-331 Prostate Neoplasms 19584056 miR-311-3p regulate ERBB-2 expression and androgen receptor signaling in prostate cancer target gene hsa-mir-331 Neoplasms [unspecific] 19584269 "miR-331-3p; a c/EBPalpha target,; Inhibits metastatic tumor antigen 1" target gene hsa-mir-122 Neoplasms [unspecific] 19584290 "down-regulated; modulates expression of immunoinhibitory molecule B7-H3;directly target B7-H3 3' untranslated region, and knock-in and knockdown of miR-29a led to down-regulation and up-regulation of B7-H3 protein expression; potential immune based therapy" target gene hsa-mir-122 Multiple Sclerosis 19617918 The genes targeted by hsa-miR-96 are involved inimmunological pathways as Interleukin signaling and in other pathways as wnt signaling target gene hsa-mir-143 Colorectal Carcinoma 19638978 MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. target gene hsa-mir-143 Melanoma 19639204 miR-27a and its target gene ZBTB10 significantly different based on the dose of genistein target gene hsa-mir-210 Lung Neoplasms 19654003 "low expression, targets pro-survival molecules MCL-1 and BCL2L2" target gene hsa-mir-200b Breast Neoplasms 19665978 "downregulated, modulate Expression of BMI1, suppressed tumor formation of normal stem cell" target gene hsa-mir-200c Neoplasms [unspecific] 19665999 inhibits through down-regulating LRP1 target gene hsa-mir-17 Lymphoma 19666108 "The expression of these genes was also reduced in response to miR-17 and miR-20a transfection, and more specifically they were also shown to contain functional miRNA recognition elements for members of the miR-17 family by reporter gene assay." target gene hsa-mir-20a Lymphoma 19666108 "The expression of these genes was also reduced in response to miR-17 and miR-20a transfection, and more specifically they were also shown to contain functional miRNA recognition elements for members of the miR-17 family by reporter gene assay." target gene hsa-mir-205 "Lymphoma, Hodgkin" 19666866 "Regulates JAK2, prognostic impact" target gene hsa-mir-197 Lung Neoplasms 19671678 regulate tumor suppressor gene FUS1 target gene hsa-mir-93 Lung Neoplasms 19671678 regulate tumor suppressor gene FUS1 target gene hsa-mir-98 Lung Neoplasms 19671678 regulate tumor suppressor gene FUS1 target gene hsa-mir-221 "Carcinoma, Hepatocellular" 19671867 MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality. target gene hsa-mir-17 Glioblastoma 19676043 "inhibite Bcl-2 and Mcl-1, induce apoptosis" target gene hsa-mir-18a Glioblastoma 19676043 "inhibite Bcl-2 and Mcl-1, induce apoptosis" target gene hsa-mir-19a Glioblastoma 19676043 "inhibite Bcl-2 and Mcl-1, induce apoptosis" target gene hsa-mir-145 Vascular Disease [unspecific] 19690387 MicroRNA-modulated targeting of vascular smooth muscle cells target gene hsa-mir-17 Vascular Disease [unspecific] 19690387 miR-17-92 and miR-17-5p/miR-20a; MicroRNA-modulated targeting of vascular smooth muscle cells target gene hsa-mir-18a Vascular Disease [unspecific] 19690387 miR-17-92 and miR-17-5p/miR-20a; MicroRNA-modulated targeting of vascular smooth muscle cells target gene hsa-mir-19a Vascular Disease [unspecific] 19690387 miR-17-92 and miR-17-5p/miR-20a; MicroRNA-modulated targeting of vascular smooth muscle cells target gene hsa-mir-20a Vascular Disease [unspecific] 19690387 miR-17-92 and miR-17-5p/miR-20a; MicroRNA-modulated targeting of vascular smooth muscle cells target gene hsa-mir-193b Breast Neoplasms 19701247 Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer. target gene hsa-mir-9 Ovarian Neoplasms 19702828 "Ovarian cancer tissues display significantly low expression of miR-9 and a high level of NF-kappaB1 compared with normal tissues, indicating that regulation of NF-kappaB1 by miR-9 is an important mechanism for miR-9 to inhibit ovarian cancer proliferation." target gene hsa-let-7d Cocaine Abuse 19703567 downregulated;These miRNAs target many genes involved in cocaine addiction. Precursor and mature miRNA quantification by qRT-PCR showed that miR-124 and let-7d are significantly downregulated target gene hsa-mir-124-1 Cocaine Abuse 19703567 downregulated;These miRNAs target many genes involved in cocaine addiction. Precursor and mature miRNA quantification by qRT-PCR showed that miR-124 and let-7d are significantly downregulated target gene hsa-mir-124-2 Cocaine Abuse 19703567 downregulated;These miRNAs target many genes involved in cocaine addiction. Precursor and mature miRNA quantification by qRT-PCR showed that miR-124 and let-7d are significantly downregulated target gene hsa-mir-124-3 Cocaine Abuse 19703567 downregulated;These miRNAs target many genes involved in cocaine addiction. Precursor and mature miRNA quantification by qRT-PCR showed that miR-124 and let-7d are significantly downregulated target gene hsa-mir-181a-2 Cocaine Abuse 19703567 "miR-124, let-7d and miR-181a may be involved in a complex feedback loop with cocaine-responsive plasticity genes" target gene hsa-mir-1-1 Rhabdomyosarcoma 19710019 inhibits rhabdomyosarcoma through downregulating c-Met target gene hsa-mir-1-2 Rhabdomyosarcoma 19710019 inhibits rhabdomyosarcoma through downregulating c-Met target gene hsa-mir-206 Rhabdomyosarcoma 19710019 inhibits rhabdomyosarcoma through downregulating c-Met target gene hsa-mir-15a Arthritis 19714650 "induction of apoptosis in the synovium of mice,suppresses apoptosis through inhibition of Bcl-2" target gene hsa-mir-15a Psoriatic Arthritis 19714650 suppresses apoptosis through inhibition of Bcl-2 target gene hsa-mir-133a-1 Cardiovascular Diseases [unspecific] 19720047 MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes target gene hsa-mir-133a-2 Cardiovascular Diseases [unspecific] 19720047 MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes target gene hsa-mir-133b Cardiovascular Diseases [unspecific] 19720047 MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes target gene hsa-mir-206 Neoplasms [unspecific] 19723635 inhibits Notch3 target gene hsa-mir-122 "Carcinoma, Hepatocellular" 19726678 "The liver specific miR-122 is frequently suppressed in primary hepatocellular carcinomas (HCCs). ADAM-10 (a distintegrin and metalloprotease family-10), SRF (serum response factor), and Igf1R (insulin like growth factor 1 receptor) that promote tumorigenesis were validated as targets of miR- 122 and were repressed by the microRNA." target gene hsa-mir-125b-1 Breast Neoplasms 19738052 hsa-mir-125b binding site in BMPR1B is Associated with Breast cancer pathogenesis target gene hsa-mir-125b-2 Breast Neoplasms 19738052 hsa-mir-125b binding site in BMPR1B is Associated with Breast cancer pathogenesis target gene hsa-mir-100 Nasopharyngeal Neoplasms 19739117 miR-100 can directly target Plk1 target gene hsa-mir-196a "Adenocarcinoma, Esophageal" 19773200 "Recent findings include the following: firstly, miRNA expression profiles can distinguish between BE and EAC; secondly, miR-196a is upregulated in EAC tissues targeting annexin A1, thereby exerting antiapoptotic effects and contributing to EAC cell survival" target gene hsa-mir-34a Glioblastoma 19773441 MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes target gene hsa-mir-10b "Fatty Liver, Non-Alcoholic" 19780876 "Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-alpha expression, a novel mechanism for the pathogenesis of NAFLD" target gene hsa-mir-125b Breast Neoplasms 19825990 "Thus, the short hairpin-looped ODN-Raf, targeting the same region of c-raf-1 as miR-125b, is a multifunctional molecule reducing the expression of oncoproteins and stimulating cell death. Both features may be useful to interfere with tumor growth." target gene hsa-mir-449a Neoplasms [unspecific] 19833767 "Our study reveals a tumor suppressor function of miR-449a/b through regulating Rb/E2F1 activity, and suggests that escape from this regulation through an aberrant epigenetic event contributes to E2F1 deregulation and unrestricted proliferation in human cancer." target gene hsa-mir-449b Neoplasms [unspecific] 19833767 "Our study reveals a tumor suppressor function of miR-449a/b through regulating Rb/E2F1 activity, and suggests that escape from this regulation through an aberrant epigenetic event contributes to E2F1 deregulation and unrestricted proliferation in human cancer." target gene hsa-mir-214 Cervical Neoplasms 19859982 these results suggest that miR-214 negatively regulates HeLa cell proliferation by targeting the noncoding regions of MEK3 and JNK1 mRNAs. target gene hsa-mir-125a Breast Neoplasms 19875930 MicroRNA-125a represses cell growth by targeting HuR in breast cancer target gene hsa-mir-513 Infection [unspecific] 19916867 These data suggest a role of miR-513 in regulating B7-H1 expression by cholangiocytes in response to C. parvum infection. target gene hsa-mir-372 Gastric Neoplasms 19937137 "Taken together, these findings demonstrate an oncogenic role for miR-372 in controlling cell growth, cell cycle, and apoptosis through down-regulation of a tumor suppressor gene, LATS2." target gene hsa-mir-17 Inflammation 19949084 "In this study, we report that TNF-mediated induction of endothelial adhesion molecules can be regulated by miRNAs that are induced by TNF. Specifically, E-selectin and ICAM-1 are targets of TNF-induced miRNAs miR-31 and miR-17-3p, respectively." target gene hsa-mir-31 Inflammation 19949084 "In this study, we report that TNF-mediated induction of endothelial adhesion molecules can be regulated by miRNAs that are induced by TNF. Specifically, E-selectin and ICAM-1 are targets of TNF-induced miRNAs miR-31 and miR-17-3p, respectively." target gene hsa-mir-221 Glioblastoma 19953484 Up-regulation of p27(kip1) by miR-221/222 antisense oligonucleotides enhances the radiosensitivity of U251 glioblastoma] target gene hsa-mir-222 Glioblastoma 19953484 Up-regulation of p27(kip1) by miR-221/222 antisense oligonucleotides enhances the radiosensitivity of U251 glioblastoma] target gene hsa-mir-181b "Carcinoma, Hepatocellular" 20023698 TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. target gene hsa-let-7a-1 Neoplasms [unspecific] 20033209 let-7a:The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice target gene hsa-let-7a-2 Neoplasms [unspecific] 20033209 let-7a:The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice target gene hsa-let-7a-3 Neoplasms [unspecific] 20033209 let-7a:The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice target gene hsa-mir-491 Colorectal Carcinoma 20039318 "miR-491:Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-X(L) in colorectal cancer cells" target gene hsa-mir-106a Neoplasms [unspecific] 20049626 "miR-106:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53" target gene hsa-mir-125a Neoplasms [unspecific] 20049626 "miR-125:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53" target gene hsa-mir-150 Neoplasms [unspecific] 20049626 "miR-150:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53" target gene hsa-mir-16-1 Neoplasms [unspecific] 20049626 "miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53" target gene hsa-mir-16-2 Neoplasms [unspecific] 20049626 "miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53" target gene hsa-mir-17 Neoplasms [unspecific] 20049626 "miR-17:miR-16, miR-17, miR-34a-c, and miR-125 served as tumor suppressor miRNAs, while miR-20, miR-106, and miR-150 acted as oncogenic miRNAs" target gene hsa-mir-20a Neoplasms [unspecific] 20049626 "miR-20:miR-16, miR-17, miR-34a-c, and miR-125 served as tumor suppressor miRNAs, while miR-20, miR-106, and miR-150 acted as oncogenic miRNAs" target gene hsa-mir-34a Neoplasms [unspecific] 20049626 "miR-34a:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53" target gene hsa-mir-34b Neoplasms [unspecific] 20049626 "miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53" target gene hsa-mir-34c Neoplasms [unspecific] 20049626 "miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53" target gene hsa-mir-497 Cerebral Ischemia 20053374 "Taken together, our data suggest that miR-497 promotes ischemic neuronal death by negatively regulating antiapoptotic proteins, bcl-2 and bcl-w." target gene hsa-mir-27a Obesity 20060380 "Together, these results suggest that miR-27a would suppress adipocyte differentiation through targeting PPARgamma and thereby down-regulation of miR-27a might be associated with adipose tissue dysregulation in obesity." target gene hsa-mir-24 Gastrointestinal Neoplasms 20062076 These findings establish a novel regulation of miR-24-related AE1 expression in gastric carcinogenesis and erythropoiesis. target gene hsa-mir-150 Gastric Neoplasms 20067763 MiR-150 promotes gastric cancer proliferation by negatively regulating the pro-apoptotic gene EGR2 target gene hsa-mir-15a Leukemia 20068100 "Compared with M non-IGHV3-23 CLL, the gene expression profile of M IGHV3-23 CLL was deprived in genes, including the growth/tumor suppressor genes PDCD4, TIA1, and RASSF5, whose downregulation is under control of miR-15a and miR-16-1." target gene hsa-mir-16-1 Leukemia 20068100 "Compared with M non-IGHV3-23 CLL, the gene expression profile of M IGHV3-23 CLL was deprived in genes, including the growth/tumor suppressor genes PDCD4, TIA1, and RASSF5, whose downregulation is under control of miR-15a and miR-16-1." target gene hsa-mir-18a Neuroblastoma 20080637 miR-18a and miR-19a target and repress the expression of estrogen receptor-alpha (ESR1) target gene hsa-mir-19a Neuroblastoma 20080637 miR-18a and miR-19a target and repress the expression of estrogen receptor-alpha (ESR1) target gene hsa-mir-223 "Diabetes Mellitus, Type 2" 20080987 "These data demonstrate a role for miR-223 in Glut4 regulation and glucose metabolism in the heart, reveal the pleiotropic effects of miRNAs across tissues, and show that miRNAs can upregulate target genes in terminally differentiated cardiomyocytes." target gene hsa-mir-126 Immune System Disease [unspecific] 20083669 These data show that miR-126 is differentially regulated in CF versus non-CF airway epithelial cells and that TOM1 is a miR-126 target that may have an important role in regulating innate immune responses in the CF lung. target gene hsa-mir-145 Colon Neoplasms 20098684 MicroRNA-145 targets YES and STAT1 in colon cancer cells. target gene hsa-mir-7-1 Breast Neoplasms 20099276 miR-7:miR-345 and miR-7 target the human multidrug resistance-associated protein 1 target gene hsa-mir-7-2 Breast Neoplasms 20099276 miR-7:miR-345 and miR-7 target the human multidrug resistance-associated protein 1 target gene hsa-mir-7-3 Breast Neoplasms 20099276 miR-7:miR-345 and miR-7 target the human multidrug resistance-associated protein 1 target gene hsa-mir-9-1 Gastric Neoplasms 20102618 miR-9 targets NF-kappaB1 and regulates gastric cancer cell growth target gene hsa-mir-9-2 Gastric Neoplasms 20102618 miR-9 targets NF-kappaB1 and regulates gastric cancer cell growth target gene hsa-mir-9-3 Gastric Neoplasms 20102618 miR-9 targets NF-kappaB1 and regulates gastric cancer cell growth target gene hsa-mir-181a "Carcinoma, Lung, Non-Small-Cell" 20145152 miR-181a and miR-630 regulate cisplatin-induced cancer cell death. target gene hsa-mir-630 "Carcinoma, Lung, Non-Small-Cell" 20145152 miR-181a and miR-630 regulate cisplatin-induced cancer cell death. target gene hsa-mir-148a Cholangiocarcinoma 20146264 "These data indicate that IL-6 can regulate the activity of DNMT-1 and expression of methylation-dependent tumor suppressor genes by modulation of miR-148a and miR-152, and provide a link between this inflammation-associated cytokine and oncogenesis in cholangiocarcinoma." target gene hsa-mir-152 Cholangiocarcinoma 20146264 "These data indicate that IL-6 can regulate the activity of DNMT-1 and expression of methylation-dependent tumor suppressor genes by modulation of miR-148a and miR-152, and provide a link between this inflammation-associated cytokine and oncogenesis in cholangiocarcinoma." target gene hsa-mir-17 Multiple Sclerosis 20148420 Functional experiments with a synthetic inhibitor of miR-17 supported the link between miRNA expression and the altered target gene expression. target gene hsa-mir-15b Neoplasms [unspecific] 20154725 "miR-15b:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373)" target gene hsa-mir-16-1 Neoplasms [unspecific] 20154725 "miR-16:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373)" target gene hsa-mir-16-2 Neoplasms [unspecific] 20154725 "miR-16:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373)" target gene hsa-mir-21 Neoplasms [unspecific] 20154725 "miR-21:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373)" target gene hsa-mir-372 Neoplasms [unspecific] 20154725 "miR-372:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373)" target gene hsa-mir-373 Neoplasms [unspecific] 20154725 "miR-373:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373)" target gene hsa-mir-181b-1 Gastric Neoplasms 20162574 miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines target gene hsa-mir-181b-1 Lung Neoplasms 20162574 miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines target gene hsa-mir-181b-2 Gastric Neoplasms 20162574 miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines target gene hsa-mir-181b-2 Lung Neoplasms 20162574 miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines target gene hsa-mir-9 Breast Neoplasms 20173740 "Here we show that miR-9, which is upregulated in breast cancer cells, directly targets CDH1, the E-cadherin-encoding messenger RNA, leading to increased cell motility and invasiveness. " target gene hsa-mir-130b Gastric Neoplasms 20176475 miR-130b:MicroRNA-130b regulates the tumour suppressor RUNX3 in gastric cancer target gene hsa-mir-133a Cardiomegaly 20177001 Our data show that reciprocal repression between miR-133 and calcineurin regulates cardiac hypertrophy. target gene hsa-mir-133b Cardiomegaly 20177001 Our data show that reciprocal repression between miR-133 and calcineurin regulates cardiac hypertrophy. target gene hsa-mir-146a Human Immunodeficiency Virus Infection 20181935 mir-146a:CCL8/MCP-2 is a target for mir-146a in HIV-1-infected human microglial cells target gene hsa-mir-29a Alzheimer Disease 20202123 miR-29a decreased in Alzheimer disease brains targets neuron navigator-3 target gene hsa-mir-181a Glioblastoma 20204284 MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2. target gene hsa-mir-29a "Leukemia, Myeloid, Acute" 20212066 Our data indicate that miR-29a regulates early hematopoiesis and suggest that miR-29a initiates AML by converting myeloid progenitors into self-renewing LSC. target gene hsa-mir-21 Lung Neoplasms 20223231 MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC) target gene hsa-mir-375 Liver Neoplasms 20226166 MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties target gene hsa-mir-20b Breast Neoplasms 20232316 miR-20b modulates VEGF expression by targeting HIF-1alpha and STAT3 in MCF-7 breast cancer cells target gene hsa-mir-138-1 Neoplasms [unspecific] 20232393 we demonstrate that miR-138 suppresses TSCC cell migration and invasion by regulating two key genes in the Rho GTPase signaling pathway target gene hsa-mir-138-2 Neoplasms [unspecific] 20232393 we demonstrate that miR-138 suppresses TSCC cell migration and invasion by regulating two key genes in the Rho GTPase signaling pathway target gene hsa-mir-218-1 Gastric Neoplasms 20300657 MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor. target gene hsa-mir-218-2 Gastric Neoplasms 20300657 MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor. target gene hsa-mir-193b Melanoma 20304954 MicroRNA-193b Represses Cell Proliferationand Regulates Cyclin D1 in Melanoma target gene hsa-mir-107 Neoplasms [unspecific] 20308559 Taken together these data suggest that miR-107 can mediate p53 regulation of hypoxic signaling and tumor angiogenesis. target gene hsa-let-7g "Carcinoma, Hepatocellular" 20309945 Hsa-let-7g inhibits proliferation of hepatocellular carcinoma Cells by down-regulation of c-Myc and Up-regulation of p16(INK4A). target gene hsa-mir-145 Prostate Neoplasms 20332243 MicroRNA145 targets BNIP3 and suppresses prostate cancer progression. target gene hsa-let-7g "Carcinoma, Hepatocellular" 20338660 Let-7g targets collagen type I alpha2 and inhibits cell migration in hepatocellular carcinoma. target gene hsa-mir-21 Breast Neoplasms 20346171 our data suggests that miR-21 could promote invasion in breast cancer cells via its regulation of TIMP3 target gene hsa-let-7a-1 "Carcinoma, Hepatocellular" 20347499 hsa-let-7a:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma target gene hsa-let-7a-2 "Carcinoma, Hepatocellular" 20347499 hsa-let-7a:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma target gene hsa-let-7a-3 "Carcinoma, Hepatocellular" 20347499 hsa-let-7a:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma target gene hsa-let-7b "Carcinoma, Hepatocellular" 20347499 hsa-let-7b:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma target gene hsa-let-7c "Carcinoma, Hepatocellular" 20347499 hsa-let-7c:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma target gene hsa-let-7d "Carcinoma, Hepatocellular" 20347499 hsa-let-7d:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma target gene hsa-let-7e "Carcinoma, Hepatocellular" 20347499 hsa-let-7e:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma target gene hsa-let-7f-1 "Carcinoma, Hepatocellular" 20347499 hsa-let-7f:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma target gene hsa-let-7f-2 "Carcinoma, Hepatocellular" 20347499 hsa-let-7f:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma target gene hsa-let-7g "Carcinoma, Hepatocellular" 20347499 hsa-let-7g:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma target gene hsa-let-7i "Carcinoma, Hepatocellular" 20347499 hsa-let-7i:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma target gene hsa-mir-34a Neoplasms [unspecific] 20351093 miR-34a:MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells target gene hsa-mir-143 Prostate Neoplasms 20353999 Our data indicate that miR-143 and miR-145 are involved in the regulation of MYO6 expression and possibly in the development of prostate cancer target gene hsa-mir-145 Prostate Neoplasms 20353999 Our data indicate that miR-143 and miR-145 are involved in the regulation of MYO6 expression and possibly in the development of prostate cancer target gene hsa-mir-155 Breast Neoplasms 20354188 MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene target gene hsa-let-7f-1 Ovarian Neoplasms 20354523 "When we co-transfected cells with pMIR-KLK10 and either let-7f, miR-224, or mR-516a, we saw decreased luciferase signal, suggesting that these miRNAs can target KLK10." target gene hsa-let-7f-2 Ovarian Neoplasms 20354523 "When we co-transfected cells with pMIR-KLK10 and either let-7f, miR-224, or mR-516a, we saw decreased luciferase signal, suggesting that these miRNAs can target KLK10." target gene hsa-mir-224 Ovarian Neoplasms 20354523 "When we co-transfected cells with pMIR-KLK10 and either let-7f, miR-224, or mR-516a, we saw decreased luciferase signal, suggesting that these miRNAs can target KLK10." target gene hsa-mir-516a-1 Ovarian Neoplasms 20354523 "When we co-transfected cells with pMIR-KLK10 and either let-7f, miR-224, or mR-516a, we saw decreased luciferase signal, suggesting that these miRNAs can target KLK10." target gene hsa-mir-516a-2 Ovarian Neoplasms 20354523 "When we co-transfected cells with pMIR-KLK10 and either let-7f, miR-224, or mR-516a, we saw decreased luciferase signal, suggesting that these miRNAs can target KLK10." target gene hsa-mir-181 "Leukemia, Lymphocytic, Chronic, B-Cell" 20357824 We recently reported that levels of TCL1 expression in B-CLL are regulated by miR-29 and miR-181 that target 3' UTR of TCL1. target gene hsa-mir-29 "Leukemia, Lymphocytic, Chronic, B-Cell" 20357824 We recently reported that levels of TCL1 expression in B-CLL are regulated by miR-29 and miR-181 that target 3' UTR of TCL1. target gene hsa-mir-602 "Carcinoma, Hepatocellular" 20364114 MicroRNA-602 regulating tumor suppressive gene RASSF1A is overexpressed in hepatitis B virus-infected liver and hepatocellular carcinoma target gene hsa-mir-602 Hepatitis B Virus Infection 20364114 MicroRNA-602 regulating tumor suppressive gene RASSF1A is overexpressed in hepatitis B virus-infected liver and hepatocellular carcinoma target gene hsa-mir-155 Breast Neoplasms 20371610 "MicroRNA-155 regulates cell survival, growth and chemosensitivity by targeting FOXO3a in breast cancer" target gene hsa-mir-512-1 "Carcinoma, Hepatocellular" 20372864 miR-512-3p:Inhibition of c-FLIP expression by miR-512-3p contributes to taxol-induced apoptosis in hepatocellular carcinoma cells target gene hsa-mir-512-2 "Carcinoma, Hepatocellular" 20372864 miR-512-3p:Inhibition of c-FLIP expression by miR-512-3p contributes to taxol-induced apoptosis in hepatocellular carcinoma cells target gene hsa-mir-219 "Child Development Disorders, Pervasive" 20374639 "Putative gene targets (ID3 and PLK2) of two RT-PCR-confirmed brain-specific miRNAs (hsa-miR-29b and hsa-miR-219-5p),were validated by miRNA overexpression or knockdown assays" target gene hsa-mir-29b "Child Development Disorders, Pervasive" 20374639 "Putative gene targets (ID3 and PLK2) of two RT-PCR-confirmed brain-specific miRNAs (hsa-miR-29b and hsa-miR-219-5p),were validated by miRNA overexpression or knockdown assays" target gene hsa-mir-15 Neoplasms [unspecific] 20385127 "Our data thus imply that miR-15a regulates cell size and proliferation by fine-tuning Dlk1 among others, and further emphasize miR-15a and DLK1 levels to play important roles in growth signaling networks." target gene hsa-mir-212 "Carcinoma, Lung, Non-Small-Cell" 20388802 miR-212:miR-212 increases tumor necrosis factor-related apoptosis-inducing ligand sensitivity in non-small cell lung cancer by targeting the antiapoptotic protein PED target gene hsa-mir-101 Alzheimer Disease 20395292 "Thus, miR-101 is a negative regulator of APP expression and affects the accumulation of Abeta, suggesting a possible role for miR-101 in neuropathological conditions." target gene hsa-mir-129 Colorectal Carcinoma 20404570 our data indicate that miR-129 plays an important role in regulating cell proliferation by downregulation of Cdk6. target gene hsa-mir-148a Prostate Neoplasms 20406806 "miR-148a:MiR-148a attenuates paclitaxel resistance of hormone-refractory, drug-resistant prostate cancer PC3 cells by regulating MSK1 expression" target gene hsa-mir-17 Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression target gene hsa-mir-17 "Leukemia, Myeloid, Acute" 20406979 miR-17:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression target gene hsa-mir-18a Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression target gene hsa-mir-18a "Leukemia, Myeloid, Acute" 20406979 miR-18a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression target gene hsa-mir-19a Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression target gene hsa-mir-19a "Leukemia, Myeloid, Acute" 20406979 miR-19a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression target gene hsa-mir-19b-1 Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression target gene hsa-mir-19b-1 "Leukemia, Myeloid, Acute" 20406979 miR-19b:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression target gene hsa-mir-19b-2 Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression target gene hsa-mir-19b-2 "Leukemia, Myeloid, Acute" 20406979 miR-19b:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression target gene hsa-mir-20a Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression target gene hsa-mir-20a "Leukemia, Myeloid, Acute" 20406979 miR-20a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression target gene hsa-mir-92a-1 "Leukemia, Myeloid, Acute" 20406979 miR-92a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression target gene hsa-mir-92a-2 "Leukemia, Myeloid, Acute" 20406979 miR-92a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression target gene hsa-mir-145 Atherosclerosis 20415654 "MicroRNAs also regulate smooth muscle cell phenotypes and control neointima formation and atherosclerosis. In this respect, miR-143 and miR-145 have been shown to play a crucial role." target gene hsa-mir-182 Lung Neoplasms 20420807 mir-182:Hsa-mir-182 suppresses lung tumorigenesis through down regulation of RGS17 expression in vitro target gene hsa-mir-26a Lymphoma 20441582 MicroRNA-26a-mediated regulation of interleukin-2 expression in transformed avian lymphocyte lines. target gene hsa-mir-151a Neoplasms [unspecific] 20445018 "miR-151:down-modulating MPL and other targets of miR-28, and of related miR-708 and miR-151, could contribute to MPN pathogenicity" target gene hsa-mir-28 Neoplasms [unspecific] 20445018 "miR-28:down-modulating MPL and other targets of miR-28, and of related miR-708 and miR-151, could contribute to MPN pathogenicity" target gene hsa-mir-708 Neoplasms [unspecific] 20445018 "miR-708:down-modulating MPL and other targets of miR-28, and of related miR-708 and miR-151, could contribute to MPN pathogenicity" target gene hsa-mir-155 Preeclampsia 20452491 miR-155:MicroRNA-155 contributes to preeclampsia by down-regulating CYR61 target gene hsa-mir-20a Ovarian Neoplasms 20458444 miR-20a:miR-20a promotes proliferation and invasion by targeting APP in human ovarian cancer cells target gene hsa-mir-125b-1 Breast Neoplasms 20460378 MicroRNA-125b:MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression target gene hsa-mir-125b-2 Breast Neoplasms 20460378 MicroRNA-125b:MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression target gene hsa-mir-133b Parkinson Disease 20468068 MiR-133b has been implicated in Parkinson's disease (PD) by a mechanism that involves the regulation of the transcription factor PITX3. target gene hsa-mir-34a Glioma 20470934 "Our results demonstrate that miR-34a acts as a tumor suppressor in p53-mutant glioma cells U251, partially through regulating SIRT1." target gene hsa-mir-21 Osteosarcoma 20480266 MicroRNA-21 is involved in osteosarcoma cell invasion and migration. target gene hsa-mir-92a-1 Breast Neoplasms 20484043 miR-92:Estrogen receptor {beta}1 expression is regulated by miR-92 in breast cancer target gene hsa-mir-92a-2 Breast Neoplasms 20484043 miR-92:Estrogen receptor {beta}1 expression is regulated by miR-92 in breast cancer target gene hsa-mir-146a Chronic Heart Failure 20495188 These findings suggested that the up-regulation of miR-146a after Dox treatment is involved in acute Dox-induced cardiotoxicity by targeting ErbB4. target gene hsa-mir-146a Psoriatic Arthritis 20500689 miR-146a:The role of microRNA-146a (miR-146a) and its target IL-1R-associated kinase (IRAK1) in psoriatic arthritis susceptibility target gene hsa-mir-199a-1 "Carcinoma, Hepatocellular" 20501828 MiR-199a-3p:MiR-199a-3p regulates mTOR and c-Met to influence the doxorubicin sensitivity of human hepatocarcinoma cells target gene hsa-mir-199a-2 "Carcinoma, Hepatocellular" 20501828 MiR-199a-3p:MiR-199a-3p regulates mTOR and c-Met to influence the doxorubicin sensitivity of human hepatocarcinoma cells target gene hsa-mir-17 Breast Neoplasms 20505989 These findings suggest that miR-17-5p plays an important role in breast cancer cell invasion and migration by suppressing HBP1 and subsequent activation of Wnt/¦Â-catenin. target gene hsa-mir-331 Gastric Neoplasms 20510161 miRNA-331-3p:miRNA-331-3p directly targets E2F1 and induces growth arrest in human gastric cancer target gene hsa-mir-200a Breast Neoplasms 20514023 miR-200a:Our results suggest that the miR-200 family has a tumor-suppressor function by negatively regulating EGF-driven cell invasion target gene hsa-mir-200b Breast Neoplasms 20514023 miR-200b:Our results suggest that the miR-200 family has a tumor-suppressor function by negatively regulating EGF-driven cell invasion target gene hsa-mir-200c Breast Neoplasms 20514023 mir-200c:Our results suggest that the miR-200 family has a tumor-suppressor function by negatively regulating EGF-driven cell invasion target gene hsa-mir-1226 Hematologic Neoplasms 20514397 These findings indicate that expression of the MUC1 oncoprotein is downregulated by miR-1226 and that miR-1226 thereby functions as a tumor suppressor by promoting the induction of cell death. target gene hsa-mir-25 "Muscular Dystrophy, Facioscapulohumeral" 20519410 "miR-25:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence" target gene hsa-mir-32 "Muscular Dystrophy, Facioscapulohumeral" 20519410 "miR-32:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence" target gene hsa-mir-363 "Muscular Dystrophy, Facioscapulohumeral" 20519410 "miR-363:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence" target gene hsa-mir-367 "Muscular Dystrophy, Facioscapulohumeral" 20519410 "miR-367:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence" target gene hsa-mir-92a-1 "Muscular Dystrophy, Facioscapulohumeral" 20519410 "miR-92:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence" target gene hsa-mir-92a-2 "Muscular Dystrophy, Facioscapulohumeral" 20519410 "miR-92:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence" target gene hsa-mir-661 Breast Neoplasms 20543867 miR-661:miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers target gene hsa-mir-375 Gastric Neoplasms 20548334 MiR-375:MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2 target gene hsa-mir-155 Cardiovascular Diseases [unspecific] 20550618 MicroRNA-155 prevents necrotic cell death in human cardiomyocyte progenitor cells via targeting RIP1. target gene hsa-mir-200a Pancreatic Neoplasms 20551052 miR-200a:The elevated serum levels of miR-200a and miR-200b in most patients with pancreatic cancer could have diagnostic utility target gene hsa-mir-200b Pancreatic Neoplasms 20551052 miR-200b:The elevated serum levels of miR-200a and miR-200b in most patients with pancreatic cancer could have diagnostic utility target gene hsa-mir-23b Kidney Neoplasms 20562915 "miR-23b:miR-23b targets proline oxidase, a novel tumor suppressor protein in renal cancer" target gene hsa-mir-22 Neoplasms [unspecific] 20562918 miR-22:miR-22 acts as a tumor suppressor through direct repression of MYCBP expression and subsequent reduction of oncogenic c-Myc activities. target gene hsa-mir-1 Cardiomegaly 20571053 "Taken together, our results demonstrate that the cytoskeleton regulatory protein twinfilin-1 is a novel target of miR-1, and that reduction of miR-1 by hypertrophic stimuli induces the upregulation of twinfilin-1, which in turn evokes hypertrophy through the regulation of cardiac cytoskeleton." target gene hsa-mir-101-1 Neoplasms [unspecific] 20586854 miR-101:Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation target gene hsa-mir-101-2 Neoplasms [unspecific] 20586854 miR-101:Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation target gene hsa-mir-185 Neoplasms [unspecific] 20603620 miRNA-185:MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers target gene hsa-mir-96 Pancreatic Neoplasms 20610624 miRNA-96:miRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer target gene hsa-mir-149 Neoplasms [unspecific] 20623644 miR-149:miR-149* induces apoptosis by inhibiting Akt1 and E2F1 in human cancer cells target gene hsa-mir-27a Ovarian Neoplasms 20624637 MiR-27a:MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells target gene hsa-mir-10a Atherosclerosis 20624982 miR-10a:miR-10a contributes to the regulation of proinflammatory endothelial phenotypes in athero-susceptible regions in vivo target gene hsa-mir-135a Inflammation 20634564 "Specifically, miR-181a and b, miR-9, miR-204, miR-199b, and miR-135a suppressed SIRT1 protein expression." target gene hsa-mir-181a Inflammation 20634564 "Specifically, miR-181a and b, miR-9, miR-204, miR-199b, and miR-135a suppressed SIRT1 protein expression." target gene hsa-mir-181b Inflammation 20634564 "Specifically, miR-181a and b, miR-9, miR-204, miR-199b, and miR-135a suppressed SIRT1 protein expression." target gene hsa-mir-199b Inflammation 20634564 "Specifically, miR-181a and b, miR-9, miR-204, miR-199b, and miR-135a suppressed SIRT1 protein expression." target gene hsa-mir-204 Inflammation 20634564 "Specifically, miR-181a and b, miR-9, miR-204, miR-199b, and miR-135a suppressed SIRT1 protein expression." target gene hsa-mir-9 Inflammation 20634564 "Specifically, miR-181a and b, miR-9, miR-204, miR-199b, and miR-135a suppressed SIRT1 protein expression." target gene hsa-mir-137 Melanoma 20644734 miR-137:Our data show that miR-148 and miR-137 present an additional level of regulating Mitf expression in melanocytes and melanoma cells. target gene hsa-mir-148a Melanoma 20644734 miR-148:Our data show that miR-148 and miR-137 present an additional level of regulating Mitf expression in melanocytes and melanoma cells. target gene hsa-mir-27a Ovarian Neoplasms 20646448 "The expression of miR-27a is upregulated in A2780/Taxol cells, which may regulate MDR1 and P-gp expression by targeting HIPK2." target gene hsa-mir-326 Glioma 20667897 Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells target gene hsa-mir-217 Pancreatic Neoplasms 20675343 The miR-217 microRNA functions as a potential tumor suppressor in pancreatic ductal adenocarcinoma by targeting KRAS. target gene hsa-mir-489 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 20700123 miR-489:miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma target gene hsa-mir-21 Barrett Esophagus 20702469 "These data support a significant role for PDCD4 downregulation in the progression of BM to BAc, and confirm miR-21 as a negative regulator of PDCD4 in vivo. Further efforts are needed to validate PDCD4 as a potential prognostic marker in patients with Barrett's oesophagus." target gene hsa-mir-106b Alzheimer Disease 20709030 miR-106b aberrantly expressed in a double transgenic mouse model for Alzheimer's disease targets TGF-¦Â type II receptor. target gene hsa-mir-146a "Carcinoma, Renal Cell" 20709800 Loss of inducible nitric oxide synthase expression in the mouse renal cell carcinoma cell line RENCA is mediated by microRNA miR-146a. target gene hsa-mir-101-1 Gastric Neoplasms 20712078 miR-101-3p: MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion target gene hsa-mir-101-2 Gastric Neoplasms 20712078 miR-101-3p: MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion target gene hsa-mir-125a "Carcinoma, Lung, Non-Small-Cell" 20723344 hsa-miR-125a-5p could up-regulate Rock-1 and enhance invasion in lung cancer cells. target gene hsa-mir-145 Colon Neoplasms 20737575 "Taken together, these results suggest that miR-145 functions as a tumor suppressor by down-regulating oncogenic FLI1 in colon cancer." target gene hsa-mir-221 Glioblastoma 20813046 "To our knowledge, these data indicate for the first time that miR-221/222 directly regulate apoptosis by targeting PUMA in glioblastoma and that miR-221/222 could be potential therapeutic targets for glioblastoma intervention." target gene hsa-mir-222 Glioblastoma 20813046 "To our knowledge, these data indicate for the first time that miR-221/222 directly regulate apoptosis by targeting PUMA in glioblastoma and that miR-221/222 could be potential therapeutic targets for glioblastoma intervention." target gene hsa-mir-24-1 "Squamous Cell Carcinoma, Tongue" 20816961 miR-24:MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma target gene hsa-mir-24-2 "Squamous Cell Carcinoma, Tongue" 20816961 miR-24:MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma target gene hsa-mir-148a Prostate Neoplasms 20820187 miR-148a is an androgen-responsive microRNA that promotes LNCaP prostate cell growth by repressing its target CAND1 expression. target gene hsa-mir-21 "Carcinoma, Colon" 20826792 miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells. target gene hsa-mir-31 "Carcinoma, Colon" 20826792 miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells. target gene hsa-mir-21 "Squamous Cell Carcinoma, Oral" 20831814 Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma. target gene hsa-mir-494 Ischemia 20837890 miR-494:MicroRNA-494 targeting both proapoptotic and antiapoptotic proteins protects against ischemia/reperfusion-induced cardiac injury target gene hsa-mir-494 Ischemia-Reperfusion Injury 20837890 miR-494:MicroRNA-494 targeting both proapoptotic and antiapoptotic proteins protects against ischemia/reperfusion-induced cardiac injury target gene hsa-mir-145 Vascular Injuries 20841497 "In addition, specific miRNAs such as miR-145, miR-21, and miR-221 have been found to regulate neointimal hyperplasia following vascular injury, which provides interesting possibilities for future herapeutical targets against vascular disease." target gene hsa-mir-1 Bladder Neoplasms 20843712 "Our data indicate that LASP1 may have an oncogenic function and that it might be regulated by miR-1, miR-133a, and miR-218, which may function as tumor suppressive miRNAs in BC." target gene hsa-mir-133a Bladder Neoplasms 20843712 "Our data indicate that LASP1 may have an oncogenic function and that it might be regulated by miR-1, miR-133a, and miR-218, which may function as tumor suppressive miRNAs in BC." target gene hsa-mir-145 Bladder Neoplasms 20843712 "Our data indicate that LASP1 may have an oncogenic function and that it might be regulated by miR-1, miR-133a, and miR-218, which may function as tumor suppressive miRNAs in BC." target gene hsa-mir-17 Neoplasms [unspecific] 20851997 "miR-17-92 inhibits apoptosis by suppressing Pten via the miR-19 components, our results indicate that this miRNA cluster promotes tumorigenesis by antagonizing both tumor-suppressing mechanisms, apoptosis, and senescence, through the activities of different miRNA components encoded in this cluster" target gene hsa-mir-18 Neoplasms [unspecific] 20851997 "miR-17-92 inhibits apoptosis by suppressing Pten via the miR-19 components, our results indicate that this miRNA cluster promotes tumorigenesis by antagonizing both tumor-suppressing mechanisms, apoptosis, and senescence, through the activities of different miRNA components encoded in this cluster" target gene hsa-mir-19a Neoplasms [unspecific] 20851997 "miR-17-92 inhibits apoptosis by suppressing Pten via the miR-19 components, our results indicate that this miRNA cluster promotes tumorigenesis by antagonizing both tumor-suppressing mechanisms, apoptosis, and senescence, through the activities of different miRNA components encoded in this cluster" target gene hsa-mir-19b-1 Neoplasms [unspecific] 20851997 "miR-17-92 inhibits apoptosis by suppressing Pten via the miR-19 components, our results indicate that this miRNA cluster promotes tumorigenesis by antagonizing both tumor-suppressing mechanisms, apoptosis, and senescence, through the activities of different miRNA components encoded in this cluster" target gene hsa-mir-20a Neoplasms [unspecific] 20851997 "miR-17-92 inhibits apoptosis by suppressing Pten via the miR-19 components, our results indicate that this miRNA cluster promotes tumorigenesis by antagonizing both tumor-suppressing mechanisms, apoptosis, and senescence, through the activities of different miRNA components encoded in this cluster" target gene hsa-mir-92-1 Neoplasms [unspecific] 20851997 "miR-17-92 inhibits apoptosis by suppressing Pten via the miR-19 components, our results indicate that this miRNA cluster promotes tumorigenesis by antagonizing both tumor-suppressing mechanisms, apoptosis, and senescence, through the activities of different miRNA components encoded in this cluster" target gene hsa-mir-107 Leukemia 20884628 "Recent findings indicate that GRN is regulated strongly by the microRNA miR-107, which functionally overlaps with miR-15, miR-16, and miR-195 due to a common 5' sequence critical for target specificity. " target gene hsa-mir-15 Leukemia 20884628 "Recent findings indicate that GRN is regulated strongly by the microRNA miR-107, which functionally overlaps with miR-15, miR-16, and miR-195 due to a common 5' sequence critical for target specificity. " target gene hsa-mir-16 Leukemia 20884628 "Recent findings indicate that GRN is regulated strongly by the microRNA miR-107, which functionally overlaps with miR-15, miR-16, and miR-195 due to a common 5' sequence critical for target specificity. " target gene hsa-mir-195 Leukemia 20884628 "Recent findings indicate that GRN is regulated strongly by the microRNA miR-107, which functionally overlaps with miR-15, miR-16, and miR-195 due to a common 5' sequence critical for target specificity. " target gene hsa-mir-181a Congenital Heart Diseases 20884876 "We showed that Dicer loss of function was, at least in part, mediated by miRNA-21 (miR-21) and miRNA-181a (miR-181a), which in turn repressed the protein level of Sprouty 2, an inhibitor of Erk1/2 signaling." target gene hsa-mir-21 Congenital Heart Diseases 20884876 "We showed that Dicer loss of function was, at least in part, mediated by miRNA-21 (miR-21) and miRNA-181a (miR-181a), which in turn repressed the protein level of Sprouty 2, an inhibitor of Erk1/2 signaling." target gene hsa-mir-196b "Leukemia, Lymphoblastic, Acute" 20924650 Results of the present study revealed that miR-196b becomes non-functional in T-cell ALL as a consequence of mutations in 3'-UTR of c-myc gene in T-cell ALL cellular models. target gene hsa-mir-125b Neoplasms [unspecific] 20935678 "Thus, beyond miR-125b and miR-504, the human TP53 gene is negatively regulated by two more miRNAs: miR-25 and miR-30d." target gene hsa-mir-25 Neoplasms [unspecific] 20935678 "Thus, beyond miR-125b and miR-504, the human TP53 gene is negatively regulated by two more miRNAs: miR-25 and miR-30d." target gene hsa-mir-30d Neoplasms [unspecific] 20935678 "Thus, beyond miR-125b and miR-504, the human TP53 gene is negatively regulated by two more miRNAs: miR-25 and miR-30d." target gene hsa-mir-504 Neoplasms [unspecific] 20935678 "Thus, beyond miR-125b and miR-504, the human TP53 gene is negatively regulated by two more miRNAs: miR-25 and miR-30d." target gene hsa-mir-146b Inflammation 20956612 "e.g., miR-146b targeted NF-¦ÊB signaling, and miR-219 targeted 5-lipoxygenase and reduced leukotriene production." target gene hsa-mir-219 Inflammation 20956612 "e.g., miR-146b targeted NF-¦ÊB signaling, and miR-219 targeted 5-lipoxygenase and reduced leukotriene production." target gene hsa-mir-93 Glioblastoma 20956944 MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integrin-¦Â8. target gene hsa-mir-16 Multiple Myeloma 20962322 "We validated designated genes showing binding sites within the conserved 3'-UTR and also within the mRNA coding region as direct miR-16 targets, thus indicating that the miRNAs may have many more targets than anticipated by conventional prediction methods." target gene hsa-mir-31 Endometrial Neoplasms 20980827 "These findings provide new insights into tumor-stroma interaction and document that miR-31 and its target gene SATB2, are involved in regulation of tumor cell motility." target gene hsa-mir-107 Gastrointestinal Neoplasms 21029372 "MicroRNA-107, an oncogene microRNA that regulates tumour invasion and metastasis by targeting DICER1 in gastric cancer." target gene hsa-mir-137 Melanoma 21051724 The results showed that miR-137 can act as a tumor suppressor in uveal melanoma cell proliferation through downregulation of the targets MITF and CDK6. miR-137 may be epigenetically silenced during uveal melanoma tumorigenesis. target gene hsa-mir-34a "Carcinoma, Rectal" 21067862 "These findings suggest that miR-34a targeting the Sirt1 and E2F3 genes could negatively regulate, at least in part, the resistance to 5-FU in human colorectal cancer DLD-1 cells." target gene hsa-mir-101 Immune System Disease [unspecific] 21068409 "Together, these results indicate that miR-101 regulates the innate immune responses of macrophages to LPS through targeting MKP-1." target gene hsa-mir-221 Prostate Neoplasms 21071579 This study demonstrates for the first time that prostate cancer cells have decreased level of ARHI which could be caused by direct targeting of 3'UTR of ARHI by miR221/222. target gene hsa-mir-211 Melanoma 21072171 "our findings that miR-211 is a direct posttranscriptional regulator of KCNMA1 expression as well as the dependence of this miRNA's expression on MITF activity, establishes miR-211 as an important regulatory agent in human melanoma." target gene hsa-mir-196a Melanoma 21077158 "As it was stated before that miR-196a might negatively regulate expression of the transcription factor HOX-C8, we analyzed HOX-C8 levels in NHEMs and melanoma cells and found a strong up-regulation of HOX-C8 expression in malignant melanoma cell lines and tissue samples compared with melanocytes." target gene hsa-mir-138 "Squamous Cell Carcinoma, Tongue" 21079996 Identification and experimental validation of G protein alpha inhibiting activity polypeptide 2 (GNAI2) as a microRNA-138 target in tongue squamous cell carcinoma. target gene hsa-mir-191 Ovarian Neoplasms 21084273 "We conclude that acquisition of an illegitimate miR-191 target site causes downregulation of MDM4 expression,thereby significantly delaying ovarian carcinoma progression and tumor-related death." target gene hsa-mir-373 Cholangiocarcinoma 21086164 "miR-373 is one negative regulator of MBD2. In hilar cholangiocarcinoma, down-expression of miR-373 leads to increase of MBD2, which in turn suppresses the methylation-mediated gene such as RASSF1A." target gene hsa-mir-145 Lung Neoplasms 21092188 miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc. target gene hsa-mir-221 Glioblastoma 21109963 "These results were confirmed by the protein expression of p27kip1, the validated target of miR-221/222, the effect on cell cycle arrest in G1 phase, and the impact on cell apoptosis." target gene hsa-mir-222 Glioblastoma 21109963 "These results were confirmed by the protein expression of p27kip1, the validated target of miR-221/222, the effect on cell cycle arrest in G1 phase, and the impact on cell apoptosis." target gene hsa-let-7 Ovarian Neoplasms 21109987 Involvement of let-7/miR-98 microRNAs in the regulation of progesterone receptor membrane component 1 expression in ovarian cancer cells. target gene hsa-mir-98 Ovarian Neoplasms 21109987 Involvement of let-7/miR-98 microRNAs in the regulation of progesterone receptor membrane component 1 expression in ovarian cancer cells. target gene hsa-mir-10a Neuroblastoma 21118818 MicroRNAs-10a and -10b contribute to retinoic acid-induced differentiation of neuroblastoma cells and target the alternative splicing regulatory factor SFRS1 target gene hsa-mir-296 Prostate Neoplasms 21138859 Regulation of HMGA1 expression by microRNA296 affects prostate cancer growth and invasion target gene hsa-mir-128-1 Neuroblastoma 21143953 Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells. target gene hsa-mir-128-2 Neuroblastoma 21143953 Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells. target gene hsa-mir-17 Neuroblastoma 21145484 The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma. target gene hsa-mir-18a Neuroblastoma 21145484 The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma. target gene hsa-mir-19a Neuroblastoma 21145484 The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma. target gene hsa-mir-19b-1 Neuroblastoma 21145484 The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma. target gene hsa-mir-20a Neuroblastoma 21145484 The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma. target gene hsa-mir-92a-1 Neuroblastoma 21145484 The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-beta Pathway in Neuroblastoma. target gene hsa-mir-43c Gastrointestinal Neoplasms 21156161 "Furthermore, a luciferase reporter assay demonstrates that miR-43c directly targets adherens junctions' transmembrane protein (VEZT) and suppresses VEZT protein expression." target gene hsa-mir-218-1 "Carcinoma, Lung, Non-Small-Cell" 21159652 Paxillin Predicts Survival and Relapse in Non-Small Cell Lung Cancer by MicroRNA-218 Targeting. target gene hsa-mir-218-2 "Carcinoma, Lung, Non-Small-Cell" 21159652 Paxillin Predicts Survival and Relapse in Non-Small Cell Lung Cancer by MicroRNA-218 Targeting. target gene hsa-mir-146a Thyroid Neoplasms 21159845 Papillary Thyroid Carcinoma (PTC). Direct interaction with THRB was shown for miR-21 and miR-146a. target gene hsa-mir-21 Thyroid Neoplasms 21159845 Papillary Thyroid Carcinoma (PTC). Direct interaction with THRB was shown for miR-21 and miR-146a. target gene hsa-mir-181a-1 "Squamous Cell Carcinoma, Oral" 21167132 miR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras target gene hsa-mir-181a-2 "Squamous Cell Carcinoma, Oral" 21167132 miR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras target gene hsa-mir-21 Dementia 21170291 MicroRNA-21 dysregulates the expression of MEF2C in neurons in monkey and human SIV/HIV neurological disease. target gene hsa-mir-593 Esophageal Neoplasms 21170987 Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal cancer. target gene hsa-mir-103a-1 Alzheimer Disease 21179570 "microRNAs 103 and 107 repress translation of cofilin, and that reduced levels of miR-103 or miR-107 are associated with elevated cofilin protein levels and formation of rod-like structures in a transgenic mouse model of AD" target gene hsa-mir-103a-2 Alzheimer Disease 21179570 "microRNAs 103 and 107 repress translation of cofilin, and that reduced levels of miR-103 or miR-107 are associated with elevated cofilin protein levels and formation of rod-like structures in a transgenic mouse model of AD" target gene hsa-mir-107 Alzheimer Disease 21179570 "microRNAs 103 and 107 repress translation of cofilin, and that reduced levels of miR-103 or miR-107 are associated with elevated cofilin protein levels and formation of rod-like structures in a transgenic mouse model of AD" target gene hsa-mir-34a Neuroblastoma 21182263 "YY1 is a negative regulator of p53, and it plays an essential role in cancer biology. Therefore, YY1 is another important direct target of miR-34a which closely regulates TP53 activities." target gene hsa-mir-185 Colorectal Carcinoma 21186079 "miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells.miR-185 is a negative regulator of RhoA and Cdc42 and their cellular activities, and could inhibit proliferation and invasion of colorectal cancer" target gene hsa-mir-21 Leukemia 21187093 Involvement of miR-21 in resistance to daunorubicin by regulating PTEN expression in the leukaemia K562 cell line. target gene hsa-mir-199a-1 Neoplasms [unspecific] 21189327 microRNAs miR-199a-5p and -3p target the Brm subunit of SWI/SNF to generate a double-negative feedback loop in a variety of human cancers. target gene hsa-mir-199a-2 Neoplasms [unspecific] 21189327 microRNAs miR-199a-5p and -3p target the Brm subunit of SWI/SNF to generate a double-negative feedback loop in a variety of human cancers. target gene hsa-mir-135a "Carcinoma, Rectal" 21192341 "In this issue, Li and colleagues describe a novel way of targeting miRNA, by using a naturally occurring anti-cancer compound found in mistletoe which they showed to down-regulate miR-135a&b, which target the 3' untranslated region of adenomatous polyposis coli gene, the inactivation of which is a major initiating event in colorectal tumourigenesis." target gene hsa-mir-135b "Carcinoma, Rectal" 21192341 "In this issue, Li and colleagues describe a novel way of targeting miRNA, by using a naturally occurring anti-cancer compound found in mistletoe which they showed to down-regulate miR-135a&b, which target the 3' untranslated region of adenomatous polyposis coli gene, the inactivation of which is a major initiating event in colorectal tumourigenesis." target gene hsa-mir-143 Prostate Neoplasms 21197560 miR-143 decreases prostate cancer cells proliferation and migration and enhances their sensitivity to docetaxel through suppression of KRAS target gene hsa-mir-26a-1 Nasopharyngeal Neoplasms 21199804 MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2 target gene hsa-mir-26a-2 Nasopharyngeal Neoplasms 21199804 MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2 target gene hsa-mir-96 Breast Neoplasms 21203424 Unregulated miR-96 Induces Cell Proliferation in Human Breast Cancer by Downregulating Transcriptional Factor FOXO3a. target gene hsa-mir-203 Urinary Bladder Cancer 21205209 microRNA-203 suppresses bladder cancer development by repressing bcl-w expression. target gene hsa-mir-15a Patau Syndrome 21205891 MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13. target gene hsa-mir-16-1 Patau Syndrome 21205891 MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13. target gene hsa-mir-16-2 Patau Syndrome 21205891 MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13. target gene hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. target gene hsa-mir-15b "Leukemia, Lymphocytic, Chronic, B-Cell" 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. target gene hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. target gene hsa-mir-16-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. target gene hsa-mir-195 "Leukemia, Lymphocytic, Chronic, B-Cell" 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. target gene hsa-mir-34b "Leukemia, Lymphocytic, Chronic, B-Cell" 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. target gene hsa-mir-34c "Leukemia, Lymphocytic, Chronic, B-Cell" 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. target gene hsa-mir-10a Neuroblastoma 21212796 MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2. target gene hsa-mir-10b Neuroblastoma 21212796 MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2. target gene hsa-mir-31 "Muscular Dystrophy, Duchenne" 21212803 miR-31 represses dystrophin expression by targeting its 3' untranslated region. target gene hsa-mir-214 Urinary Bladder Cancer 21216304 Plexin-B1 is a target of miR-214 in cervical cancer and promotes the growth and invasion of HeLa Cells. target gene hsa-mir-328 Breast Neoplasms 21219875 Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328; -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells. target gene hsa-mir-519c Breast Neoplasms 21219875 Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328; -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells. target gene hsa-mir-520h Breast Neoplasms 21219875 Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328; -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells. target gene hsa-mir-125a Gastric Neoplasms 21220473 "MicroRNA-125a-5p is an independent prognostic factor in gastric cancer,and inhibits the proliferation of human gastric cancer cells in combination with trastuzumab." target gene hsa-mir-137 Gastric Neoplasms 21221794 miR-137 Is Frequently Down-Regulated in Gastric Cancer and Is a Negative Regulator of Cdc42. target gene hsa-mir-616 Prostate Neoplasms 21224345 microRNA-616 Induces Androgen-Independent Growth of Prostate Cancer Cells by Suppressing Expression of Tissue Factor Pathway Inhibitor TFPI-2. target gene hsa-mir-376c Ovarian Neoplasms 21224400 MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance. target gene hsa-mir-200a Prostate Neoplasms 21224847 Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells. target gene hsa-mir-200b Prostate Neoplasms 21224847 Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells. target gene hsa-mir-200c Prostate Neoplasms 21224847 Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells. target gene hsa-mir-200a Breast Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. target gene hsa-mir-200a Pancreatic Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. target gene hsa-mir-200b Breast Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. target gene hsa-mir-200b Pancreatic Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. target gene hsa-mir-200c Breast Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. target gene hsa-mir-200c Pancreatic Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. target gene hsa-mir-9-1 Gastric Neoplasms 21225631 MiR-9 down-regulates CDX2 expression in gastric cancer cells. target gene hsa-mir-9-2 Gastric Neoplasms 21225631 MiR-9 down-regulates CDX2 expression in gastric cancer cells. target gene hsa-mir-9-3 Gastric Neoplasms 21225631 MiR-9 down-regulates CDX2 expression in gastric cancer cells. target gene hsa-mir-340 Breast Neoplasms 21225860 miR-340 inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c-Met target gene hsa-mir-885 Neuroblastoma 21233845 "MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival." target gene hsa-mir-155 Preeclampsia 21234519 microRNA-155 regulates angiotensin II type 1 receptor expression in umbilical vein endothelial cells from severely pre-eclamptic pregnant women. target gene hsa-mir-146a Atherosclerosis 21236257 Our study clearly revealed that miRNA-146a regulates the maturation process and pro-inflammatory cytokine secretion in DCs by targeting CD40L in ox-LDL-stimulated DCs. target gene hsa-mir-34a Prostate Neoplasms 21240262 The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. target gene hsa-mir-20a Colorectal Carcinoma 21242194 miR-20a targets BNIP2 and contributes chemotherapeutic resistance in colorectal adenocarcinoma SW480 and SW620 cell lines. target gene hsa-mir-126 Breast Neoplasms 21249429 Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2. target gene hsa-mir-485 Leukemia 21252292 Novel regulation of NF-YB by miR-485-3p affects expression of DNA topoisomerase II{alpha} and drug responsiveness in human lymphoblastic leukemia CEM cells. target gene hsa-mir-145 Prostate Neoplasms 21258769 "Restoration of miR-145 expression suppresses cell proliferation, migration and invasion in prostate cancer by targeting FSCN1." target gene hsa-mir-497 Gastrointestinal Neoplasms 21258880 miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2. target gene hsa-mir-497 Lung Neoplasms 21258880 miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2. target gene hsa-mir-26b Glioma 21264258 "This study demonstrated that miR-26b may act as a tumor suppressor in glioma and it directly regulates EphA2 expression. EphA2 is a direct target of miR-26b, and the down-regulation of EphA2 mediated by miR-26b is dependent on the binding of miR-26b to a" target gene hsa-mir-107 Gastrointestinal Neoplasms 21264532 "miR-107 targets cyclin-dependent kinase 6 expression, induces cell cycle G1 arrest and inhibits invasion in gastric cancer cells." target gene hsa-mir-101-1 "Carcinoma, Lung, Non-Small-Cell" 21270667 MicroRNA-101 Exerts Tumor-Suppressive Functions in Non-small Cell Lung Cancer through Directly Targeting Enhancer of Zeste Homolog 2. target gene hsa-mir-101-2 "Carcinoma, Lung, Non-Small-Cell" 21270667 MicroRNA-101 Exerts Tumor-Suppressive Functions in Non-small Cell Lung Cancer through Directly Targeting Enhancer of Zeste Homolog 2. target gene hsa-mir-19a Esophageal Neoplasms 21271217 TNF-alpha is a novel target of miR-19a. target gene hsa-mir-381 Systemic Mastocytosis 21273305 We found that miR-539 and miR-381 are downregulated by KIT signaling and they repressed MITF expression through conserved miRNA binding sites in the MITF 3' UTR. target gene hsa-mir-539 Systemic Mastocytosis 21273305 We found that miR-539 and miR-381 are downregulated by KIT signaling and they repressed MITF expression through conserved miRNA binding sites in the MITF 3' UTR. target gene hsa-mir-29a Inflammation 21276447 microRNA-29a could regulate pro-inflammatory cytokine secretion and scavenger receptor expression by targeting lipoprotein lipase in oxLDL-stimulated dendritic cells. target gene hsa-mir-221 Colorectal Carcinoma 21278784 MicroRNA-221 inhibits CDKN1C/p57 expression in human colorectal carcinoma. target gene hsa-mir-21 Glioma 21278789 Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas. target gene hsa-mir-137 Melanoma 21278922 MicroRNA-137 Targets Carboxyl-terminal Binding Protein 1 in Melanoma Cell Lines. target gene hsa-mir-145 Lung Neoplasms 21289483 MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1. target gene hsa-mir-141 Esophageal Neoplasms 21289630 MicroRNA-141 confers resistance to cisplatin-induced apoptosis by targeting YAP1 in human esophageal squamous cell carcinoma. target gene hsa-mir-101 Glioblastoma 21297974 Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2. target gene hsa-mir-203 Esophageal Neoplasms 21299870 MicroRNA-203 inhibits cell proliferation by repressing DeltaNp63 expression in human esophageal squamous cell carcinoma. target gene hsa-mir-203 "Squamous Cell Carcinoma, Esophageal" 21299870 MicroRNA-203 inhibits cell proliferation by repressing DeltaNp63 expression in human esophageal squamous cell carcinoma. target gene hsa-mir-1-1 Urinary Bladder Cancer 21304530 The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. target gene hsa-mir-1-2 Urinary Bladder Cancer 21304530 The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. target gene hsa-mir-133a-1 Urinary Bladder Cancer 21304530 The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. target gene hsa-mir-133a-2 Urinary Bladder Cancer 21304530 The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. target gene hsa-mir-126 Gastrointestinal Neoplasms 21304604 "miR-126 is a novel miRNA that targets SOX2, and PLAC1 may be a novel downstream target gene of SOX2 in gastric cancer cells. These findings suggest that aberrant over-expression of miR-126 and consequent SOX2 down-regulation may contribute to gastric carc" target gene hsa-mir-125b-1 Prostate Neoplasms 21308711 "miR-125b suppresses MUC1 translation in LNCaP cells and that an anti-sense miR-125b upregulates expression of MUC1 protein. In addition, stable expression of miR-125b in DU145 cells resulted in decreases in MUC1 levels." target gene hsa-mir-125b-2 Prostate Neoplasms 21308711 "miR-125b suppresses MUC1 translation in LNCaP cells and that an anti-sense miR-125b upregulates expression of MUC1 protein. In addition, stable expression of miR-125b in DU145 cells resulted in decreases in MUC1 levels." target gene hsa-mir-155 Inflammation 21310411 "HUVECs highly expressed miR-155 may co-target AT1R and Ets-1 while miR-221/222 targets Ets-1, which indirectly regulate the expression of several inflammatory molecules of ECs, and therefore attenuate the adhesion of Jurkat T cells to activated HUVECs and" target gene hsa-mir-221 Inflammation 21310411 "HUVECs highly expressed miR-155 may co-target AT1R and Ets-1 while miR-221/222 targets Ets-1, which indirectly regulate the expression of several inflammatory molecules of ECs, and therefore attenuate the adhesion of Jurkat T cells to activated HUVECs and" target gene hsa-mir-222 Inflammation 21310411 "HUVECs highly expressed miR-155 may co-target AT1R and Ets-1 while miR-221/222 targets Ets-1, which indirectly regulate the expression of several inflammatory molecules of ECs, and therefore attenuate the adhesion of Jurkat T cells to activated HUVECs and" target gene hsa-mir-29c Diabetes Mellitus 21310958 "MicroRNA-29c is a signature MicroRNA under high glucose conditions which targets sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy." target gene hsa-mir-21 Prostate Neoplasms 21317927 MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4 target gene hsa-mir-21 Neoplasms [unspecific] 21328460 miR-21 downregulates the tumor suppressor P12(CDK2AP1) and Stimulates Cell Proliferation and Invasion. target gene hsa-mir-132 Pancreatic Neoplasms 21329664 "miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor, rb1." target gene hsa-mir-212 Pancreatic Neoplasms 21329664 miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor. target gene hsa-mir-34b Colorectal Carcinoma 21329882 "MK5 regulates translation of Myc, since it is required for expression of miR-34b and miR-34c that bind to the 3'UTR of MYC. MK5 activates miR-34b/c expression via phosphorylation of FoxO3a, thereby promoting nuclear localization of FoxO3a and enabling it" target gene hsa-mir-34c Colorectal Carcinoma 21329882 "MK5 regulates translation of Myc, since it is required for expression of miR-34b and miR-34c that bind to the 3'UTR of MYC. MK5 activates miR-34b/c expression via phosphorylation of FoxO3a, thereby promoting nuclear localization of FoxO3a and enabling it" target gene hsa-mir-520b Breast Neoplasms 21343296 miR-520b regulates migration of breast cancer cells through targeting hepatitis B X-interacting protein and interleukin-8. target gene hsa-mir-135b Prostate Neoplasms 21343391 "3'UTR-binding assays validated 13 miRNAs that are able to regulate this long AR 3'UTR (miR-135b, miR-185, miR-297, miR-299-3p, miR-34a, miR-34c, miR-371-3p, miR-421, miR-449a, miR-449b, miR-634, miR-654-5p, and miR-9)." target gene hsa-mir-127 Breast Neoplasms 21343399 "Analyses of miRNA expression profiles identified numerous miRNAs implicated in cell proliferation including miR-127, -197, -222, and -223 targeting CXCL12." target gene hsa-let-7a-1 Gastrointestinal Neoplasms 21349817 let-7a is significant in suppressing gastric cancer growth in vivo and in vitro and provided the first evidence that RAB40C is negatively regulated by let-7a at the post-transcriptional level via binding to the 3'-untranslated region of RAB40C mRNA in gas target gene hsa-let-7a-2 Gastrointestinal Neoplasms 21349817 let-7a is significant in suppressing gastric cancer growth in vivo and in vitro and provided the first evidence that RAB40C is negatively regulated by let-7a at the post-transcriptional level via binding to the 3'-untranslated region of RAB40C mRNA in gas target gene hsa-let-7a-3 Gastrointestinal Neoplasms 21349817 let-7a is significant in suppressing gastric cancer growth in vivo and in vitro and provided the first evidence that RAB40C is negatively regulated by let-7a at the post-transcriptional level via binding to the 3'-untranslated region of RAB40C mRNA in gas target gene hsa-mir-133a-1 "Squamous Cell Carcinoma, Esophageal" 21351259 "miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma." target gene hsa-mir-133a-2 "Squamous Cell Carcinoma, Esophageal" 21351259 "miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma." target gene hsa-mir-133b "Squamous Cell Carcinoma, Esophageal" 21351259 "miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma." target gene hsa-mir-145 "Squamous Cell Carcinoma, Esophageal" 21351259 "miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma." target gene hsa-mir-451a "Carcinoma, Lung, Non-Small-Cell" 21358675 MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14). target gene hsa-mir-16-1 Laryngeal Neoplasms 21360639 MicroRNA-16 targets zyxin and promotes cell motility in human laryngeal carcinoma cell line HEp-2. target gene hsa-mir-16-2 Laryngeal Neoplasms 21360639 MicroRNA-16 targets zyxin and promotes cell motility in human laryngeal carcinoma cell line HEp-2. target gene hsa-mir-145 "Adenocarcinoma, Endometrial" 21365617 Up-regulation of microRNA-145 promotes differentiation by repressing OCT4 in human endometrial adenocarcinoma cells. target gene hsa-mir-34a Leukemia 21367750 miR-34a induces the down-regulation of both E2F1 and B-Myb oncogenes in leukemic cells. target gene hsa-mir-101-1 Nasopharyngeal Neoplasms 21368858 "Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98." target gene hsa-mir-101-2 Nasopharyngeal Neoplasms 21368858 "Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98." target gene hsa-mir-26a-1 Nasopharyngeal Neoplasms 21368858 "Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98." target gene hsa-mir-26a-2 Nasopharyngeal Neoplasms 21368858 "Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98." target gene hsa-mir-98 Nasopharyngeal Neoplasms 21368858 "Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101, and miR-98." target gene hsa-mir-21 Pancreatic Neoplasms 21376256 Bcl-2 Upregulation Induced by miR-21 Via a Direct Interaction Is Associated with Apoptosis and Chemoresistance in MIA PaCa-2 Pancreatic Cancer Cells. target gene hsa-mir-1-1 Head And Neck Neoplasms 21378409 miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. target gene hsa-mir-1-1 "Squamous Cell Carcinoma, Head and Neck" 21378409 miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. target gene hsa-mir-1-2 Head And Neck Neoplasms 21378409 miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. target gene hsa-mir-1-2 "Squamous Cell Carcinoma, Head and Neck" 21378409 miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. target gene hsa-mir-9-1 Glioblastoma 21385897 miR-9 suppresses mesenchymal differentiation in glioblastoma by downregulating expression of JAK kinases and inhibiting activation of STAT3. target gene hsa-mir-9-2 Glioblastoma 21385897 miR-9 suppresses mesenchymal differentiation in glioblastoma by downregulating expression of JAK kinases and inhibiting activation of STAT3. target gene hsa-mir-9-3 Glioblastoma 21385897 miR-9 suppresses mesenchymal differentiation in glioblastoma by downregulating expression of JAK kinases and inhibiting activation of STAT3. target gene hsa-mir-218-1 Nasopharyngeal Neoplasms 21385904 miR-218 Suppresses Nasopharyngeal Cancer Progression through Downregulation of Survivin and the SLIT2-ROBO1 Pathway. target gene hsa-mir-218-2 Nasopharyngeal Neoplasms 21385904 miR-218 Suppresses Nasopharyngeal Cancer Progression through Downregulation of Survivin and the SLIT2-ROBO1 Pathway. target gene hsa-mir-133a-1 Urinary Bladder Cancer 21396852 MiR-133a induces apoptosis through direct regulation of GSTP1 in bladder cancer cell lines. target gene hsa-mir-204 Endometrial Neoplasms 21400511 Dysregulation of microRNA-204 mediates migration and invasion of endometrial cancer by regulating FOXC1. target gene hsa-mir-125b-1 Psoriasis 21412257 "MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2." target gene hsa-mir-125b-2 Psoriasis 21412257 "MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2." target gene hsa-mir-204 Gastric Neoplasms 21416062 "MiR-204, which was predicted to target ezrin, was downregulated in gastric cancer cells and gastric carcinomas. MiR-204 inhibited ezrin expression, Ras activation, cell growth and cell migration" target gene hsa-mir-10b Glioblastoma 21419107 MicroRNA-10b induces glioma cell invasion by modulating MMP-14 and uPAR expression via HOXD10. target gene hsa-mir-205 Esophageal Neoplasms 21426561 MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells. target gene hsa-mir-205 "Squamous Cell Carcinoma, Esophageal" 21426561 MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells. target gene hsa-mir-95 Colorectal Carcinoma 21427358 MicroRNA-95 Promotes Cell Proliferation and Targets Sorting Nexin 1 in Human Colorectal Carcinoma. target gene hsa-mir-126 "Carcinoma, Lung, Non-Small-Cell" 21439283 miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5. target gene hsa-mir-125b-1 Breast Neoplasms 21444677 miR-125b is Methylated and Functions as A Tumor Suppressor by Regulating the ETS1 proto-oncogene in Human Invasive Breast Cancer. target gene hsa-mir-125b-2 Breast Neoplasms 21444677 miR-125b is Methylated and Functions as A Tumor Suppressor by Regulating the ETS1 proto-oncogene in Human Invasive Breast Cancer. target gene hsa-mir-204 Prostate Neoplasms 21446014 "PDEF expression is regulated via a functional microRNA-204 (miR-204) binding site within the 3'UTR. Furthermore, we demonstrate the biologic significance of miR-204 expression and that miR-204 is over-expressed in human prostate cancer specimens." target gene hsa-mir-205 Melanoma 21454583 miR-205 suppresses melanoma cell proliferation and induces senescence via regulation of E2F1. target gene hsa-mir-7-1 Neurofibromatosis type 2 21454924 "We found that miR-7 functions as a tumor suppressor by targeting proteins in three major oncogenic pathways - EGFR, Pak1, and Ack1." target gene hsa-mir-7-2 Neurofibromatosis type 2 21454924 "We found that miR-7 functions as a tumor suppressor by targeting proteins in three major oncogenic pathways - EGFR, Pak1, and Ack1." target gene hsa-mir-7-3 Neurofibromatosis type 2 21454924 "We found that miR-7 functions as a tumor suppressor by targeting proteins in three major oncogenic pathways - EGFR, Pak1, and Ack1." target gene hsa-mir-148a Colorectal Carcinoma 21455217 MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer. target gene hsa-mir-24-2 Breast Neoplasms 21463514 miR-24-2 controls H2AFX expression regardless of gene copy number alteration and induces apoptosis by targeting anti-apoptotic gene BCL-2: a potential for therapeutic intervention. target gene hsa-let-7g Lung Neoplasms 21464588 miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFKB1. target gene hsa-mir-9-1 Lung Neoplasms 21464588 miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFKB1. target gene hsa-mir-9-2 Lung Neoplasms 21464588 miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFKB1. target gene hsa-mir-9-3 Lung Neoplasms 21464588 miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFKB1. target gene hsa-mir-155 Melanoma 21466664 MicroRNA-155 Targets the SKI Gene in Human Melanoma Cell Lines target gene hsa-mir-214 Melanoma 21468029 miR-214 is highly expressed in human melanomas and contributes to melanoma tumour progression through suppression of TFAP2C target gene hsa-mir-100 Endometrial Neoplasms 21472251 "hsa-mir-100 and hsa-miR-99a were predicted to target ESR1, and hsa-miR-378 and hsa-miR-768-3p to target PGR. Hsa-miR-100 was significantly down-regulated in the estrogen-dependent endometrial cancer samples as compared to the estrogen-independent samples and thus has the potential to target ESR1." target gene hsa-mir-378a Endometrial Neoplasms 21472251 "hsa-mir-100 and hsa-miR-99a were predicted to target ESR1, and hsa-miR-378 and hsa-miR-768-3p to target PGR. Hsa-miR-100 was significantly down-regulated in the estrogen-dependent endometrial cancer samples as compared to the estrogen-independent samples and thus has the potential to target ESR1." target gene hsa-mir-99a Endometrial Neoplasms 21472251 "hsa-mir-100 and hsa-miR-99a were predicted to target ESR1, and hsa-miR-378 and hsa-miR-768-3p to target PGR. Hsa-miR-100 was significantly down-regulated in the estrogen-dependent endometrial cancer samples as compared to the estrogen-independent samples and thus has the potential to target ESR1." target gene hsa-mir-145 Lung Neoplasms 21479367 microRNA-145 suppresses lung adenocarcinoma-initiating cell proliferation by targeting OCT4. target gene hsa-mir-373 "Carcinoma, Hepatocellular" 21481188 miR-373 can regulate cell cycle progression by targeting PPP6C transcripts and promotes the growth activity of hepatocellular carcinoma cells in vitro. This miRNA functions as an oncogene in hepatocellular carcinoma. target gene hsa-mir-142 "Carcinoma, Hepatocellular" 21482222 "MicroRNA-142-3p, a new regulator of RAC1, suppresses the migration and invasion of hepatocellular carcinoma cells." target gene hsa-mir-221 Prostate Neoplasms 21487968 MiR-221 expression affects invasion potential of human prostate carcinoma cell lines by targeting DVL2. target gene hsa-mir-223 "Carcinoma, Hepatocellular" 21492514 microRNA-223 and its target gene oncogene c-myc have roles in hepatocellular carcinoma pathogenesis. target gene hsa-mir-145 Lung Neoplasms 21496429 miR-145 Inhibits Lung Adenocarcinoma Stem Cells Proliferation by Targeting OCT4 Gene. target gene hsa-mir-18a Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. target gene hsa-mir-18b Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. target gene hsa-mir-19a Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. target gene hsa-mir-19b-1 Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. target gene hsa-mir-19b-2 Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. target gene hsa-mir-26b Breast Neoplasms 21510944 MicroRNA-26b is underexpressed in human breast cancer and induces cell apoptosis by targeting SLC7A11. target gene hsa-mir-143 Leukemia 21518477 "the expression of miR-143 was negatively correlated with the expression of DNMT3A mRNA, a known target gene of miR-143." target gene hsa-mir-519d "Carcinoma, Hepatocellular" 21524841 MicroRNA-519d targets MKi67 and suppresses cell growth in the hepatocellular carcinoma cell line QGY-7703. target gene hsa-mir-622 Gastric Neoplasms 21528065 Down-regulation of miR-622 in gastric cancer promotes cellular invasion and tumor metastasis by targeting ING1 gene. target gene hsa-mir-200a Ovarian Neoplasms 21529905 MicroRNA-200a inhibits CD133/1+ ovarian cancer stem cells migration and invasion by targeting E-cadherin repressor ZEB2. target gene hsa-mir-9-1 Glioblastoma 21531766 ID4 Imparts Chemoresistance and Cancer Stemness to Glioma Cells by Derepressing miR-9*-Mediated Suppression of SOX2. target gene hsa-mir-9-2 Glioblastoma 21531766 ID4 Imparts Chemoresistance and Cancer Stemness to Glioma Cells by Derepressing miR-9*-Mediated Suppression of SOX2. target gene hsa-mir-9-3 Glioblastoma 21531766 ID4 Imparts Chemoresistance and Cancer Stemness to Glioma Cells by Derepressing miR-9*-Mediated Suppression of SOX2. target gene hsa-mir-101-1 "Squamous Cell Carcinoma, Head and Neck" 21532618 The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma. target gene hsa-mir-101-2 "Squamous Cell Carcinoma, Head and Neck" 21532618 The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma. target gene hsa-let-7f-1 Gastric Neoplasms 21533124 MicroRNA Let-7f Inhibits Tumor Invasion and Metastasis by Targeting MYH9 in Human Gastric Cancer. target gene hsa-let-7f-2 Gastric Neoplasms 21533124 MicroRNA Let-7f Inhibits Tumor Invasion and Metastasis by Targeting MYH9 in Human Gastric Cancer. target gene hsa-mir-221 Colorectal Carcinoma 21538272 MicroRNA-221 controls CDKN1C/P57 expression in human colorectal carcinoma target gene hsa-mir-379 "Carcinoma, Hepatocellular" 21540293 Down-regulation of ABCC2 protein expression in HepG2 cells after rifampicin treatment is mediated by microRNA-379. target gene hsa-mir-21 Colorectal Carcinoma 21546206 "This study demonstrates the inverse relationship between miR-21 and PDCD4, thus suggesting that miR-21 post-transcriptionally modulates PDCD4 via mRNA degradation. Pharmacological manipulation of the miR-21/PDCD4 axis could represent a novel therapeutic strategy in the treatment of colorectal cancer." target gene hsa-mir-29c Esophageal Neoplasms 21551130 miR-29c induces cell cycle arrest in Esophageal Squamous Cell Carcinoma by modulating Cyclin E expression. target gene hsa-mir-29c "Squamous Cell Carcinoma, Esophageal" 21551130 miR-29c induces cell cycle arrest in Esophageal Squamous Cell Carcinoma by modulating Cyclin E expression. target gene hsa-mir-148a Gastric Neoplasms 21552422 miR-148a Promoted Cell Proliferation by Targeting p27 in Gastric Cancer Cells. target gene hsa-mir-375 Gastrointestinal Neoplasms 21557705 "The genes targeted by miR-375, including JAK2 and 3'-phosphoinositide dependent protein kinase-1(PDK1), are also candidates for gastric cancer therapy" target gene hsa-mir-146a Sepsis 21562054 MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-¦Á during TLR4-induced gene reprogramming. target gene hsa-mir-342 Colorectal Carcinoma 21565830 MicroRNA-342 Inhibits Colorectal Cancer Cell Proliferation and Invasion by Directly Targeting DNA Methyltransferase 1. target gene hsa-mir-34a "Leukemia, Lymphocytic, Chronic, B-Cell" 21565980 Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network. target gene hsa-mir-29a "Carcinoma, Hepatocellular" 21573166 Upregulated MicroRNA-29a by Hepatitis B Virus X Protein Enhances Hepatoma Cell Migration by Targeting PTEN in Cell Culture Model. target gene hsa-mir-150 Inflammatory Bowel Diseases 21590770 "Together, the present study presents the first evidence that miR-150 and its targeting of c-Myb may serve as a new mechanism underlying the colonic epithelial disruption in DSS-induced murine experimental colitis and in active human IBD." target gene hsa-mir-375 Prostate Neoplasms 21593139 miRNA-375 Downregulated Sec23A protein in prostate carcinoma. target gene hsa-mir-22 Colorectal Carcinoma 21594648 Overexpression of miR-22 reverses paclitaxel-induced chemoresistance through activation of PTEN signaling in p53-mutated colon cancer cells. target gene hsa-let-7a Esophageal Neoplasms 21600139 "Eighteen miRNAs had their target genes, 10 of them had the potential to individually target up to 200 mRNAs. Hsa-let-7a, hsa-miR-185, hsa-miR-141, hsa-miR-92b, hsa-miR-22 and hsa-miR-301a were known as important genes associated with radioresistance." target gene hsa-mir-141 Esophageal Neoplasms 21600139 "Eighteen miRNAs had their target genes, 10 of them had the potential to individually target up to 200 mRNAs. Hsa-let-7a, hsa-miR-185, hsa-miR-141, hsa-miR-92b, hsa-miR-22 and hsa-miR-301a were known as important genes associated with radioresistance." target gene hsa-mir-185 Esophageal Neoplasms 21600139 "Eighteen miRNAs had their target genes, 10 of them had the potential to individually target up to 200 mRNAs. Hsa-let-7a, hsa-miR-185, hsa-miR-141, hsa-miR-92b, hsa-miR-22 and hsa-miR-301a were known as important genes associated with radioresistance." target gene hsa-mir-22 Esophageal Neoplasms 21600139 "Eighteen miRNAs had their target genes, 10 of them had the potential to individually target up to 200 mRNAs. Hsa-let-7a, hsa-miR-185, hsa-miR-141, hsa-miR-92b, hsa-miR-22 and hsa-miR-301a were known as important genes associated with radioresistance." target gene hsa-mir-301a Esophageal Neoplasms 21600139 "Eighteen miRNAs had their target genes, 10 of them had the potential to individually target up to 200 mRNAs. Hsa-let-7a, hsa-miR-185, hsa-miR-141, hsa-miR-92b, hsa-miR-22 and hsa-miR-301a were known as important genes associated with radioresistance." target gene hsa-mir-92b Esophageal Neoplasms 21600139 "Eighteen miRNAs had their target genes, 10 of them had the potential to individually target up to 200 mRNAs. Hsa-let-7a, hsa-miR-185, hsa-miR-141, hsa-miR-92b, hsa-miR-22 and hsa-miR-301a were known as important genes associated with radioresistance." target gene hsa-mir-21 Systemic Lupus Erythematosus 21602271 miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression.Upregulated miR-21 affects PDCD4 expression and regulates aberrant T cell responses in human SLE. target gene hsa-mir-372 Hepatitis B Virus Infection 21608007 MicroRNAs-372/373 promote the expression of hepatitis B Virus through the targeting of nuclear factor I/B. target gene hsa-mir-373 Hepatitis B Virus Infection 21608007 MicroRNAs-372/373 promote the expression of hepatitis B Virus through the targeting of nuclear factor I/B. target gene hsa-mir-146a Lymphoma 21610143 "MicroRNA-146a downregulates NF{kappa}B activity via targeting TRAF6, and functions as a tumor suppressor having strong prognostic implications in NK/T cell lymphoma." target gene hsa-let-7a-1 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. target gene hsa-let-7a-2 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. target gene hsa-let-7a-3 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. target gene hsa-let-7b Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. target gene hsa-let-7c Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. target gene hsa-let-7d Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. target gene hsa-let-7e Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. target gene hsa-let-7f-1 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. target gene hsa-let-7f-2 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. target gene hsa-let-7g Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. target gene hsa-let-7i Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. target gene hsa-mir-335 Breast Neoplasms 21618216 "Breast miR-335 regulates the known BRCA1 activators ER§Ø©ã IGF1R, SP1 and the repressor ID4, including a feedback regulation of miR-335 expression by estrogens. Overexpression of miR-335 resulted in an upregulation of BRCA1 mRNA expression.miR-335 affects different targets in the upstream BRCA1-regulatory cascade with impact on key cellular functions such as proliferation and apoptosis." target gene hsa-mir-195 Cardiovascular Diseases [unspecific] 21622680 MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1. target gene hsa-mir-143 Pancreatic Neoplasms 21622730 "Two miRNA candidates known to be downregulated in the majority of pancreatic cancers were selected for nanovector delivery: miR-34a, which is a component of the p53 transcriptional network and regulates cancer stem cell survival, and the miR-143/145 cluster, which together repress the expression of KRAS2 and its downstream effector Ras-responsive element binding protein-1 (RREB1)." target gene hsa-mir-145 Pancreatic Neoplasms 21622730 "Two miRNA candidates known to be downregulated in the majority of pancreatic cancers were selected for nanovector delivery: miR-34a, which is a component of the p53 transcriptional network and regulates cancer stem cell survival, and the miR-143/145 cluster, which together repress the expression of KRAS2 and its downstream effector Ras-responsive element binding protein-1 (RREB1)." target gene hsa-mir-29a "Carcinoma, Hepatocellular" 21625215 microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer. target gene hsa-mir-29b-1 "Carcinoma, Hepatocellular" 21625215 microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer. target gene hsa-mir-29b-2 "Carcinoma, Hepatocellular" 21625215 microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer. target gene hsa-mir-29c "Carcinoma, Hepatocellular" 21625215 microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer. target gene hsa-mir-223 Gastric Neoplasms 21628394 miRNA-223 Promotes Gastric Cancer Invasion and Metastasis by Targeting Tumor Suppressor EPB41L3. target gene hsa-mir-100 Breast Neoplasms 21634028 micro-RNA 100 Regulated beta-tubulin isotypes in MCF7 breast cancer cells. target gene hsa-mir-100 Urinary Bladder Cancer 21636267 Reduced expression and had carcinogenic effect through targeting PLK1 protein. target gene hsa-mir-21 Glioblastoma 21636706 Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo. target gene hsa-mir-21 Inflammation 21636785 MicroRNA-21 targets peroxisome proliferators-activated receptor-alpha in an autoregulatory loop to modulate flow-induced endothelial inflammation. target gene hsa-mir-100 "Leukemia, Myeloid, Acute" 21643017 "MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia." target gene hsa-mir-372 Urinary Bladder Cancer 21646351 "MicroRNA-372 Is Down-regulated and Targets Cyclin-dependent Kinase 2 (CDK2) and Cyclin A1 in Human Cervical Cancer, Which May Contribute to Tumorigenesis." target gene hsa-mir-106a Glioblastoma 21656380 MiR-106a inhibits glioma cell growth by targeting E2F1 independent of p53 status. target gene hsa-mir-198 "Carcinoma, Hepatocellular" 21658389 miR-198 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the HGF/c-MET pathway. target gene hsa-let-7i "Carcinoma, Hepatocellular" 21665888 "In addition, we showed that HBx up-regulated CD59 by let-7i at post-transcriptional regulation level. " target gene hsa-mir-338 "Carcinoma, Hepatocellular" 21671467 miR-338-3p suppresses invasion of liver cancer cell by targeting smoothened. target gene hsa-mir-192 "Carcinoma, Hepatocellular" 21672525 MiR-192 inhibits nucleotide excision repair by targeting ERCC3 and ERCC4 in HepG2.2.15 cells. target gene hsa-mir-124-1 "Carcinoma, Hepatocellular" 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. target gene hsa-mir-124-2 "Carcinoma, Hepatocellular" 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. target gene hsa-mir-124-3 "Carcinoma, Hepatocellular" 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. target gene hsa-mir-200c Breast Neoplasms 21682933 "Decreased expression of miRNAs of the miR-200 family has been implicated in the growth and metastasis of breast cancer cells. Of this family, miR-200c has garnered particular attention as a consequence of its ability to target ZEB1 and ZEB2, mediators of epithelial- mesenchymal transition." target gene hsa-mir-9-1 Cardiovascular Diseases [unspecific] 21684288 MicroRNA-9 is an activation-induced regulator of PDGFR-beta expression in cardiomyocytes. target gene hsa-mir-9-2 Cardiovascular Diseases [unspecific] 21684288 MicroRNA-9 is an activation-induced regulator of PDGFR-beta expression in cardiomyocytes. target gene hsa-mir-9-3 Cardiovascular Diseases [unspecific] 21684288 MicroRNA-9 is an activation-induced regulator of PDGFR-beta expression in cardiomyocytes. target gene hsa-mir-99a Psoriasis 21687694 differentially expressed. miR-99a is one of the regulators of the IGF-1R signaling pathway in keratinocytes. Activation of IGF1 signaling results in elevation of miR-99a which represses the expression of IGF-1R. target gene hsa-mir-214 Gastric Neoplasms 21688200 Down-Regulated miRNA-214 Induces a Cell Cycle G1 Arrest in Gastric Cancer Cells by Up-Regulating the PTEN Protein. target gene hsa-mir-340 Breast Neoplasms 21692045 miR-340 inhibites breast cancer cell migration and invasion through targeting of oncoprotein c-Met. target gene hsa-mir-130a "Carcinoma, Lung, Non-Small-Cell" 21706050 miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221 and 222. target gene hsa-mir-221 "Carcinoma, Lung, Non-Small-Cell" 21706050 miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221 and 222. target gene hsa-mir-222 "Carcinoma, Lung, Non-Small-Cell" 21706050 miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221 and 222. target gene hsa-mir-155 Intervertebral Disc Degeneration 21706480 Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3. target gene hsa-mir-23a Ischemia 21709246 miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia. target gene hsa-mir-148a Pancreatic Neoplasms 21709669 MicroRNA-148a is down-regulated in human pancreatic ductal adenocarcinomas and regulates cell survival by targeting CDC25B. target gene hsa-mir-488 Prostate Neoplasms 21710544 miR 488* inhibits androgen receptor expression in prostate carcinoma cells. target gene hsa-mir-302a Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. target gene hsa-mir-302b Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. target gene hsa-mir-302c Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. target gene hsa-mir-302d Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. target gene hsa-mir-367 Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. target gene hsa-mir-181c Alzheimer Disease 21720722 "Taken together, our study identifies putative target genes of miRNAs miR-9 and 181c, which may function in brain homeostasis and disease pathogenesis." target gene hsa-mir-9 Alzheimer Disease 21720722 "Taken together, our study identifies putative target genes of miRNAs miR-9 and 181c, which may function in brain homeostasis and disease pathogenesis." target gene hsa-mir-193b "Leukemia, Myeloid, Acute" 21724256 MicroRNA-193b regulates c-Kit proto-oncogene and represses cell proliferation in acute myeloid leukemia. target gene hsa-mir-187 Ovarian Neoplasms 21725366 microRNA-187 Regulates of ovarian cancer progression through targeting Disabled homolog-2. target gene hsa-mir-15b Tongue Neoplasms 21725369 MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1. target gene hsa-mir-200b Tongue Neoplasms 21725369 MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1. target gene hsa-mir-122 "Carcinoma, Hepatocellular" 21725618 miR-122 inhibits viral replication and cell proliferation in hepatitis B virus-related hepatocellular carcinoma and targets NDRG3. target gene hsa-mir-206 Myocardial Infarction 21731608 "HMGB1 injected into chronically failing hearts enhanced LV function and attenuated LV remodelling; these effects were associated with cardiac regeneration, increased collagenolytic activity, miR-206 overexpression and miR-206 -mediated inhibition of TIMP-3." target gene hsa-mir-10 Pancreatic Neoplasms 21738581 Predicted target mRNAs FGFR1 (miR-10) and MLH1 (miR-155) were found downregulated. target gene hsa-mir-155 Pancreatic Neoplasms 21738581 Predicted target mRNAs FGFR1 (miR-10) and MLH1 (miR-155) were found downregulated. target gene hsa-mir-34a Glioblastoma 21743299 MicroRNA-34a targets notch1 and inhibits cell proliferation in glioblastoma multiforme. target gene hsa-mir-221 Glioblastoma 21743492 miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTP mu. target gene hsa-mir-222 Glioblastoma 21743492 miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTP mu. target gene hsa-mir-7-1 "Carcinoma, Lung, Non-Small-Cell" 21750649 MicroRNA-7 inhibits the growth of human non-small cell lung cancer A549 cells through targeting BCL-2. target gene hsa-mir-7-2 "Carcinoma, Lung, Non-Small-Cell" 21750649 MicroRNA-7 inhibits the growth of human non-small cell lung cancer A549 cells through targeting BCL-2. target gene hsa-mir-7-3 "Carcinoma, Lung, Non-Small-Cell" 21750649 MicroRNA-7 inhibits the growth of human non-small cell lung cancer A549 cells through targeting BCL-2. target gene hsa-mir-1-1 Thyroid Neoplasms 21752897 "MiR-1 suppress Thyroid Cancer by Targeting CCND2, CXCR4, and SDF-1{alpha}" target gene hsa-mir-1-2 Thyroid Neoplasms 21752897 "MiR-1 suppress Thyroid Cancer by Targeting CCND2, CXCR4, and SDF-1{alpha}" target gene hsa-mir-375 "Squamous Cell Carcinoma, Head and Neck" 21753766 Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC). target gene hsa-mir-21 Breast Neoplasms 21761201 "3,3'-Diindolylmethane inhibits breast cancer cell growth via miR-21-mediated Cdc25A degradation." target gene hsa-mir-29c "Carcinoma, Hepatocellular" 21763284 "miR-29c targets TNFAIP3, inhibits cell proliferation and induces apoptosis in hepatitis B virus-related hepatocellular carcinoma." target gene hsa-mir-106a Breast Neoplasms 21765466 "The experimental results using MDA-MB-231 and MCF-7 human breast cancer cells confirm that miRNAs derived from these clusters, containing miR-17-5p, miR-20a, miR-106a, miR-106b and miR-93, negatively regulate ZBTB4 expression." target gene hsa-mir-106b Breast Neoplasms 21765466 "The experimental results using MDA-MB-231 and MCF-7 human breast cancer cells confirm that miRNAs derived from these clusters, containing miR-17-5p, miR-20a, miR-106a, miR-106b and miR-93, negatively regulate ZBTB4 expression." target gene hsa-mir-17 Breast Neoplasms 21765466 "The experimental results using MDA-MB-231 and MCF-7 human breast cancer cells confirm that miRNAs derived from these clusters, containing miR-17-5p, miR-20a, miR-106a, miR-106b and miR-93, negatively regulate ZBTB4 expression." target gene hsa-mir-20a Breast Neoplasms 21765466 "The experimental results using MDA-MB-231 and MCF-7 human breast cancer cells confirm that miRNAs derived from these clusters, containing miR-17-5p, miR-20a, miR-106a, miR-106b and miR-93, negatively regulate ZBTB4 expression." target gene hsa-mir-93 Breast Neoplasms 21765466 "The experimental results using MDA-MB-231 and MCF-7 human breast cancer cells confirm that miRNAs derived from these clusters, containing miR-17-5p, miR-20a, miR-106a, miR-106b and miR-93, negatively regulate ZBTB4 expression." target gene hsa-mir-133a-1 Hypertension 21769867 "MiR-133a regulates collagen 1A1, which has potential role in myocardial fibrosis in angiotensin II dependent hypertension." target gene hsa-mir-133a-2 Hypertension 21769867 "MiR-133a regulates collagen 1A1, which has potential role in myocardial fibrosis in angiotensin II dependent hypertension." target gene hsa-mir-125a Lung Neoplasms 21777146 MicroRNA HSA-miR-125a-5p induces apoptosis by activating p53 in lung cancer cells. target gene hsa-mir-143 Urinary Bladder Cancer 21790228 Expression of miR-143 Reduces Growth and Migration of Human Bladder Carcinoma Cells by Targeting Cyclooxygenase-2. target gene hsa-mir-29b-1 "Carcinoma, Hepatocellular" 21793034 "MicroRNA-29b suppresses tumor angiogenesis, invasion and metastasis by regulating MMP-2 expression." target gene hsa-mir-29b-2 "Carcinoma, Hepatocellular" 21793034 "MicroRNA-29b suppresses tumor angiogenesis, invasion and metastasis by regulating MMP-2 expression." target gene hsa-mir-218-1 "Squamous Cell Carcinoma, Oral" 21795477 The tumor suppressive microRNA miR-218 targets the mTOR component Rictor and inhibits AKT phosphorylation in oral cancer. target gene hsa-mir-218-2 "Squamous Cell Carcinoma, Oral" 21795477 The tumor suppressive microRNA miR-218 targets the mTOR component Rictor and inhibits AKT phosphorylation in oral cancer. target gene hsa-mir-17 Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma target gene hsa-mir-18a Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma target gene hsa-mir-19a Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma target gene hsa-mir-19b-1 Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma target gene hsa-mir-20a Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma target gene hsa-mir-92a-1 Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma target gene hsa-mir-210 Preeclampsia 21801864 miR-210 Targets Iron-Sulfur Cluster Scaffold Homologue target gene hsa-mir-491 Hepatitis C Virus Infection 21802413 miR-491 was involved in regulation of HCV replication via the PI3 kinase/Akt pathway. target gene hsa-mir-122 "Carcinoma, Hepatocellular" 21802841 MicroRNA-122 sensitizes HCC cancer cells to adriamycin and vincristine through modulating expression of MDR and inducing cell cycle arrest. target gene hsa-mir-199a-1 "Carcinoma, Hepatocellular" 21807947 MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. target gene hsa-mir-199a-1 Urinary Bladder Cancer 21807947 MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. target gene hsa-mir-199a-2 "Carcinoma, Hepatocellular" 21807947 MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. target gene hsa-mir-199a-2 Urinary Bladder Cancer 21807947 MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. target gene hsa-mir-147 Dengue Virus Infection 21810247 "a microRNA which may negatively regulate pro-inflammatory cytokines in dengue infected peripheral blood cells, mIR-147 (NMES1)." target gene hsa-mir-375 "Squamous Cell Carcinoma, Esophageal" 21813472 MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor. target gene hsa-mir-34a Breast Neoplasms 21814748 Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA. target gene hsa-mir-106b Laryngeal Neoplasms 21819631 MiR-106b promotes cell proliferation via targeting RB in laryngeal carcinoma. target gene hsa-mir-21 "Carcinoma, Renal Cell" 21820586 miR-21 Modulates Cell Apoptosis by Targeting Multiple Genes in Renal Cell Carcinoma. target gene hsa-mir-21 Breast Neoplasms 21820606 MicroRNA-21 Modulates Chemosensitivity of Breast Cancer Cells to Doxorubicin by Targeting PTEN. target gene hsa-mir-335 Gastric Neoplasms 21822301 MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1. target gene hsa-mir-146b Pancreatic Neoplasms 21823013 miR-146b-5p has inhibitory effects of on cell migration and invasion of pancreatic cancer by targeting MMP16. target gene hsa-mir-125b-1 Ovarian Neoplasms 21823019 miR-125b confers resistance of ovarian cancer cells to cisplatin by targeting pro-apoptotic Bcl-2 antagonist killer 1. target gene hsa-mir-125b-2 Ovarian Neoplasms 21823019 miR-125b confers resistance of ovarian cancer cells to cisplatin by targeting pro-apoptotic Bcl-2 antagonist killer 1. target gene hsa-mir-21 Prostate Neoplasms 21826097 Spry1 is a target for miR-21-mediated gene silencing. target gene hsa-mir-451a Diabetic Nephropathy 21827757 MicroRNA-451 regulates p38 MAPK signaling by targeting of Ywhaz and suppresses the mesangial hypertrophy in early Diabetic Nephropathies. target gene hsa-let-7e Ischemia-Reperfusion Injury 21827835 MicroRNA let-7e regulates the expression of caspase-3 during apoptosis of PC12 cells following anoxia/reoxygenation injury. target gene hsa-mir-144 "Diabetes Mellitus, Type 2" 21829658 MicroRNA 144 Impairs Insulin Signaling by Inhibiting the Expression of Insulin Receptor Substrate 1 in Type 2 Diabetes Mellitus. target gene hsa-mir-107 Breast Neoplasms 21841313 miR-107 promotes tumor progression by targeting the let-7 microRNA in mice and humans. target gene hsa-mir-194-1 Endometrial Neoplasms 21851624 MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1. target gene hsa-mir-194-2 Endometrial Neoplasms 21851624 MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1. target gene hsa-let-7a-1 Ewing Sarcoma 21853155 Let-7a Is a Direct EWS-FLI-1 Target Implicated in Ewing's Sarcoma Development. target gene hsa-let-7a-2 Ewing Sarcoma 21853155 Let-7a Is a Direct EWS-FLI-1 Target Implicated in Ewing's Sarcoma Development. target gene hsa-let-7a-3 Ewing Sarcoma 21853155 Let-7a Is a Direct EWS-FLI-1 Target Implicated in Ewing's Sarcoma Development. target gene hsa-mir-375 Lung Neoplasms 21856745 miR-375 is activated by ASH1 and inhibits YAP1 in a lineage dependent manner in lung cancer. target gene hsa-mir-9-1 Glioblastoma 21857646 CAMTA1 is a novel tumour suppressor regulated by miR-9/9(*) in glioblastoma stem cells. target gene hsa-mir-9-2 Glioblastoma 21857646 CAMTA1 is a novel tumour suppressor regulated by miR-9/9(*) in glioblastoma stem cells. target gene hsa-mir-9-3 Glioblastoma 21857646 CAMTA1 is a novel tumour suppressor regulated by miR-9/9(*) in glioblastoma stem cells. target gene hsa-mir-494 Urinary Bladder Cancer 21859890 miR-494 Competitively regulates Nucleolin expression with HuR. target gene hsa-mir-542 Neoplasms [unspecific] 21860426 downregulation of miR-542-3p is significantly correlated with the upregulation of c-Src and ILK. Our results suggest that the novel c-Src-miR-542-3p-ILK-FAK circuit plays a crucial role in controlling tumor progression. target gene hsa-mir-221 Breast Neoplasms 21868360 miR-221/222 Targeting of Trichorhinophalangeal 1 (TRPS1) Promotes Epithelial-to-Mesenchymal Transition in Breast Cancer. target gene hsa-mir-222 Breast Neoplasms 21868360 miR-221/222 Targeting of Trichorhinophalangeal 1 (TRPS1) Promotes Epithelial-to-Mesenchymal Transition in Breast Cancer. target gene hsa-let-7a-1 Mesothelioma 21869823 "EphrinA1 inhibits malignant mesothelioma tumor growth via let-7 microRNA-mediated repression of the RAS oncogene.EphrinA1 activation induced several fold increases in let-7a1, let-7a3, let-7f1 and let-7f2 miRNA expression in MMCs." target gene hsa-let-7a-3 Mesothelioma 21869823 "EphrinA1 inhibits malignant mesothelioma tumor growth via let-7 microRNA-mediated repression of the RAS oncogene.EphrinA1 activation induced several fold increases in let-7a1, let-7a3, let-7f1 and let-7f2 miRNA expression in MMCs." target gene hsa-let-7f-1 Mesothelioma 21869823 "EphrinA1 inhibits malignant mesothelioma tumor growth via let-7 microRNA-mediated repression of the RAS oncogene.EphrinA1 activation induced several fold increases in let-7a1, let-7a3, let-7f1 and let-7f2 miRNA expression in MMCs." target gene hsa-let-7f-2 Mesothelioma 21869823 "EphrinA1 inhibits malignant mesothelioma tumor growth via let-7 microRNA-mediated repression of the RAS oncogene.EphrinA1 activation induced several fold increases in let-7a1, let-7a3, let-7f1 and let-7f2 miRNA expression in MMCs." target gene hsa-mir-140 Osteoarthritis 21872590 MiR-140 is co-expressed with Wwp2-C transcript and activated by Sox9 to target Sp1 in maintaining the chondrocyte proliferation. target gene hsa-mir-21 Colorectal Carcinoma 21872591 "miR-21 targets the tumor suppressor RhoB and regulates proliferation, invasion and apoptosis in colorectal cancer cells." target gene hsa-mir-146b Thyroid Neoplasms 21874046 MicroRNA miR-146b-5p regulates signal transduction of TGF-beta by repressing SMAD4 in thyroid cancer. target gene hsa-mir-216b Nasopharyngeal Neoplasms 21878506 miR-216b suppresses tumor growth and invasion by targeting KRAS in nasopharyngeal carcinoma. target gene hsa-mir-98 "Carcinoma, Lung, Non-Small-Cell" 21880462 miR-98 regulates cisplatin-induced A549 cell death by inhibiting TP53 pathway. target gene hsa-mir-125b-1 Huntington Disease 21887328 "The authors conclude that (i) miR-125b and miR-150 target p53, which in turn regulates RelA/NFkB and miR-146a expressions; (ii) reduced miR-125b and miR-150 expressions, increased p53 level and decreased RelA/NFkB and miR-146a expressions originate from mutant HTT (iii) p53 directly or indirectly regulates the expression of miR-146a." target gene hsa-mir-125b-2 Huntington Disease 21887328 "The authors conclude that (i) miR-125b and miR-150 target p53, which in turn regulates RelA/NFkB and miR-146a expressions; (ii) reduced miR-125b and miR-150 expressions, increased p53 level and decreased RelA/NFkB and miR-146a expressions originate from mutant HTT (iii) p53 directly or indirectly regulates the expression of miR-146a." target gene hsa-mir-146a Huntington Disease 21887328 "The authors conclude that (i) miR-125b and miR-150 target p53, which in turn regulates RelA/NFkB and miR-146a expressions; (ii) reduced miR-125b and miR-150 expressions, increased p53 level and decreased RelA/NFkB and miR-146a expressions originate from mutant HTT (iii) p53 directly or indirectly regulates the expression of miR-146a." target gene hsa-mir-150 Huntington Disease 21887328 "The authors conclude that (i) miR-125b and miR-150 target p53, which in turn regulates RelA/NFkB and miR-146a expressions; (ii) reduced miR-125b and miR-150 expressions, increased p53 level and decreased RelA/NFkB and miR-146a expressions originate from mutant HTT (iii) p53 directly or indirectly regulates the expression of miR-146a." target gene hsa-mir-423 "Carcinoma, Hepatocellular" 21890460 MicroRNA-423 Promotes Cell Growth and Regulates G1/S Transition by Targeting p21Cip1/Waf1 in Hepatocellular Carcinoma target gene hsa-mir-193b Melanoma 21893020 "miR-193b is expressed at a significantly lower level in malignant melanoma than in benign nevi. In a survey of melanoma samples, the level of Mcl-1 is inversely correlated with the level of miR-193b. Overexpression of miR-193b in melanoma cells represses Mcl-1 expression. Furthermore, the effect of miR-193b on the expression of Mcl-1 seems to be mediated by direct interaction between miR-193b and seed and seedless pairing sequences in the 3' untranslated region of Mcl-1 mRNA." target gene hsa-mir-373 Fibrosarcoma 21898400 miR-520c and miR-373 increased the expression of MMP9 by directly targeting the 3'UTRs of mRNAs of mTOR and SIRT1 and suppressing their translation; resulting in activation of the Ras/Raf/MEK/Erk signaling pathway and NF-§Ø¨mB; and finally increasing the mRN target gene hsa-mir-520c Fibrosarcoma 21898400 miR-520c and miR-373 increased the expression of MMP9 by directly targeting the 3'UTRs of mRNAs of mTOR and SIRT1 and suppressing their translation; resulting in activation of the Ras/Raf/MEK/Erk signaling pathway and NF-§Ø¨mB; and finally increasing the mRN target gene hsa-mir-200c Head And Neck Neoplasms 21899661 "The expression of ZEB1, a target mRNA for miR-200c, was up-regulated 3 and 6 hours after HGF stimulation." target gene hsa-mir-200c "Squamous Cell Carcinoma, Head and Neck" 21899661 "The expression of ZEB1, a target mRNA for miR-200c, was up-regulated 3 and 6 hours after HGF stimulation." target gene hsa-mir-27b Head And Neck Neoplasms 21899661 "The expression of ST14/matriptase an enzyme for extracellular matrix (ECM) degradation and HGF activation and a target mRNA for miR-27b, was drastically up-regulated in protein level after HGF stimulation." target gene hsa-mir-27b "Squamous Cell Carcinoma, Head and Neck" 21899661 "The expression of ST14/matriptase an enzyme for extracellular matrix (ECM) degradation and HGF activation and a target mRNA for miR-27b, was drastically up-regulated in protein level after HGF stimulation." target gene hsa-let-7i Coronary Artery Disease 21899916 "This study suggests that atorvastatin down-regulates TLR4 signal via let-7i expression in CAD patients, possibly contributing to the beneficial effects of atorvastatin on let-7i-mediated TLR4 signal in this disorder." target gene hsa-mir-26b Lung Neoplasms 21901137 "Expression of miR-26b was down regulated, and its target activating transcription factor 2 (ATF2) mRNA was up regulated in §Ø©ãirradiated H1299 cells." target gene hsa-mir-224 "Carcinoma, Renal Cell" 21912701 MiR-224 Targets the 3'UTR of Type 1 5'-Iodothyronine Deiodinase Possibly Contributing to Tissue Hypothyroidism in Renal Cancer. target gene hsa-mir-145 Colon Neoplasms 21917858 The expression of miR-145 is downregulated in colon and ovarian cancer tissues and cell lines. MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis. target gene hsa-mir-145 Ovarian Neoplasms 21917858 The expression of miR-145 is downregulated in colon and ovarian cancer tissues and cell lines. MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis. target gene hsa-mir-1-1 Laryngeal Neoplasms 21924268 miRNA-1 targets fibronectin1 and suppresses the migration and invasion of the HEp2 laryngeal squamous carcinoma cell line. target gene hsa-mir-1-1 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 21924268 miRNA-1 targets fibronectin1 and suppresses the migration and invasion of the HEp2 laryngeal squamous carcinoma cell line. target gene hsa-mir-1-2 Laryngeal Neoplasms 21924268 miRNA-1 targets fibronectin1 and suppresses the migration and invasion of the HEp2 laryngeal squamous carcinoma cell line. target gene hsa-mir-1-2 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 21924268 miRNA-1 targets fibronectin1 and suppresses the migration and invasion of the HEp2 laryngeal squamous carcinoma cell line. target gene hsa-mir-200a Breast Neoplasms 21926171 miR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells. target gene hsa-mir-23a Muscular Dystrophy 21926429 miR-23a suppresses the translation of both MAFbx/atrogin-1 and MuRF1 in a 3UTR-dependent manner. Ectopic expression of miR-23a is sufficient to protect muscles from atrophy in vitro and in vivo. target gene hsa-mir-504 "Squamous Cell Carcinoma, Oral" 21927029 Connective tissue growth factor modulates oral squamous cell carcinoma invasion by activating a miR-504/FOXP1 signalling. target gene hsa-mir-34a Medulloblastoma 21931765 MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15/CD133 Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma. target gene hsa-mir-499a Colorectal Carcinoma 21934092 microRNA-499-5p promotes cellular invasion and tumor metastasis in colorectal cancer by targeting FOXO4 and PDCD4. target gene hsa-mir-18a Urinary Bladder Cancer 21935572 "microRNA-18a, a member of the oncogenic miR-17-92 cluster, targets Dicer and suppresses cell proliferation in bladder cancer T24 cells." target gene hsa-mir-375 Urinary Bladder Cancer 21945323 "miR-375, Down-Regulated in Squamous Cervical Cancer, Inhibits Cell Migration and Invasion via Targeting Transcription Factor SP1." target gene hsa-mir-145 Atherosclerosis 21945499 We showed that miR-145 can regulate the fate and phenotype of human ES-pre-SMCs as they become fully differentiated SMCs. target gene hsa-mir-195 "Carcinoma, Hepatocellular" 21947305 miRNA-195 sensitizes human hepatocellular carcinoma cells to 5-FU by targeting BCL-w. target gene hsa-mir-191 Gastric Neoplasms 21947487 MicroRNA-191 targets N-deacetylase/N-sulfotransferase 1 and promotes cell growth in human gastric carcinoma cell line MGC803. target gene hsa-mir-29b-1 Multiple Myeloma 21951844 Overexpression of microRNA-29b induces apoptosis of multiple myeloma cells through down regulating Mcl-1. target gene hsa-mir-25 Cholangiocarcinoma 21953056 miR-25 targets TRAIL death Receptor-4 and promotes apoptosis resistance in cholangiocarcinoma. target gene hsa-mir-128-1 Breast Neoplasms 21953503 Reduced miR-128 in breast tumor-initiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5. target gene hsa-mir-106a "Lymphoma, Hodgkin" 21953646 MiR-17/106b seed family regulates p21 in Hodgkin's lymphoma. target gene hsa-mir-106b "Lymphoma, Hodgkin" 21953646 MiR-17/106b seed family regulates p21 in Hodgkin's lymphoma. target gene hsa-mir-17 "Lymphoma, Hodgkin" 21953646 MiR-17/106b seed family regulates p21 in Hodgkin's lymphoma. target gene hsa-mir-191 Thyroid Neoplasms 21956418 miR-191 Down-Regulation Plays a Role in Thyroid Follicular Tumors through CDK6 Targeting. target gene hsa-mir-135a-1 Endometriosis 21956427 miR-135a Regulates HOXA10 Expression in Endometriosis. target gene hsa-mir-135a-2 Endometriosis 21956427 miR-135a Regulates HOXA10 Expression in Endometriosis. target gene hsa-mir-135b Endometriosis 21956427 miR-135b Regulates HOXA10 Expression in Endometriosis. target gene hsa-mir-93 Osteosarcoma 21959981 "Levels of miR-93 were significantly higher in metastases from osteosarcoma than in paired primary tumours. When 143B and MG-63 were transfected with miR-93, clones appeared to respond differently to microRNA overexpression. Ectopic expression of miR-93 more significantly increased cell proliferation and invasivity in 143B than in MG-63 clones. Furthermore, increased mRNA and protein levels of E2F1, one of the potential miR-93 targets, were seen in osteosarcoma cellular clones and its involvement in 143B cell proliferation was confirmed by E2F1 silencing." target gene hsa-mir-125b-1 Endometrial Neoplasms 21970405 MiR-125b promotes proliferation and migration of type II endometrial carcinoma cells through targeting TP53INP1 tumor suppressor in vitro and in vivo. target gene hsa-mir-125b-2 Endometrial Neoplasms 21970405 MiR-125b promotes proliferation and migration of type II endometrial carcinoma cells through targeting TP53INP1 tumor suppressor in vitro and in vivo. target gene hsa-mir-142 "Leukemia-Lymphoma, Adult T-Cell" 21979877 miR-142-3p plans an oncogenic role in human T-cell acute lymphoblastic leukemia (T-ALL) by targeting glucocorticoid receptor-§Ø©ãand cAMP/PKA pathways. target gene hsa-mir-150 Pancreatic Neoplasms 21983127 MicroRNA-150 directly targets MUC4 and suppresses growth and malignant behavior of pancreatic cancer cells. target gene hsa-mir-181a-2 Ischemia 21983159 miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo. target gene hsa-mir-1293 Kaposi Sarcoma 21984125 "We show a direct repression of vIL-6 by hsa-miR-1293 and hIL-6 by hsa-miR-608. The repression of vIL-6 by miR-1293 was reversed by disruption of the vIL-6 miR-1293 seed match through the introduction of point mutations. In addition, expression of vIL-6 or" target gene hsa-mir-608 Kaposi Sarcoma 21984125 "We show a direct repression of vIL-6 by hsa-miR-1293 and hIL-6 by hsa-miR-608. The repression of vIL-6 by miR-1293 was reversed by disruption of the vIL-6 miR-1293 seed match through the introduction of point mutations. In addition, expression of vIL-6 or" target gene hsa-let-7c Colorectal Carcinoma 21984339 Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer. target gene hsa-mir-24-1 Breast Neoplasms 21986943 miR-24 was found to be implicated in the regulation of the EMT program in response to TGF-beta and was shown to be directly involved in the TGF-§Ø©ãinduced breast cancer cell invasiveness through Net1A regulation. target gene hsa-mir-24-2 Breast Neoplasms 21986943 miR-24 was found to be implicated in the regulation of the EMT program in response to TGF-beta and was shown to be directly involved in the TGF-§Ø©ãinduced breast cancer cell invasiveness through Net1A regulation. target gene hsa-mir-199a-1 Endometriosis 21989168 MiR-199a attenuates endometrial stromal cell invasiveness through suppression of the IKK{beta}/NF-kB pathway and reduced interleukin-8 expression. target gene hsa-mir-199a-2 Endometriosis 21989168 MiR-199a attenuates endometrial stromal cell invasiveness through suppression of the IKK{beta}/NF-kB pathway and reduced interleukin-8 expression. target gene hsa-mir-155 "Carcinoma, Hepatocellular" 21989846 Aberrant expression of microRNA 155 may accelerate cell proliferation by targeting sex-determining region Y box 6 in hepatocellular carcinoma. target gene hsa-mir-200b "Carcinoma, Lung, Non-Small-Cell" 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. target gene hsa-mir-200b Gastric Neoplasms 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. target gene hsa-mir-200c "Carcinoma, Lung, Non-Small-Cell" 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. target gene hsa-mir-200c Gastric Neoplasms 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. target gene hsa-mir-429 "Carcinoma, Lung, Non-Small-Cell" 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. target gene hsa-mir-429 Gastric Neoplasms 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. target gene hsa-mir-148a Gastric Neoplasms 21994419 MicroRNA-148a Suppresses Tumor Cell Invasion and Metastasis by Downregulating ROCK1 in Gastric Cancer. target gene hsa-mir-1-1 Chronic Obstructive Pulmonary Disease 21998125 "A reduction in expression of miR-1 (2.5-fold, p=0.01) and the myocardin-related transcription factors (MRTFs) A and B was observed in patients compared with controls (MRTF-A mRNA: twofold, p=0.028; MRTF-B mRNA: fourfold, p=0.011). miR-1 expression was associated with smoking history, lung function, fat-free mass index, 6 min walk distance and percentage of type 1 fibres. miR-133 and miR-206 were negatively correlated with daily physical activity. Insulin-like growth factor 1 mRNA was increased in the patients and miR-1 was negatively correlated with phosphorylation of the kinase Akt. Furthermore, the protein levels of histone deacetylase 4, another miR-1 target, were increased in the patients." target gene hsa-mir-1-2 Chronic Obstructive Pulmonary Disease 21998125 "A reduction in expression of miR-1 (2.5-fold, p=0.01) and the myocardin-related transcription factors (MRTFs) A and B was observed in patients compared with controls (MRTF-A mRNA: twofold, p=0.028; MRTF-B mRNA: fourfold, p=0.011). miR-1 expression was associated with smoking history, lung function, fat-free mass index, 6 min walk distance and percentage of type 1 fibres. miR-133 and miR-206 were negatively correlated with daily physical activity. Insulin-like growth factor 1 mRNA was increased in the patients and miR-1 was negatively correlated with phosphorylation of the kinase Akt. Furthermore, the protein levels of histone deacetylase 4, another miR-1 target, were increased in the patients." target gene hsa-mir-133a-1 Chronic Obstructive Pulmonary Disease 21998125 "A reduction in expression of miR-1 (2.5-fold, p=0.01) and the myocardin-related transcription factors (MRTFs) A and B was observed in patients compared with controls (MRTF-A mRNA: twofold, p=0.028; MRTF-B mRNA: fourfold, p=0.011). miR-1 expression was associated with smoking history, lung function, fat-free mass index, 6 min walk distance and percentage of type 1 fibres. miR-133 and miR-206 were negatively correlated with daily physical activity. Insulin-like growth factor 1 mRNA was increased in the patients and miR-1 was negatively correlated with phosphorylation of the kinase Akt. Furthermore, the protein levels of histone deacetylase 4, another miR-1 target, were increased in the patients." target gene hsa-mir-133a-2 Chronic Obstructive Pulmonary Disease 21998125 "A reduction in expression of miR-1 (2.5-fold, p=0.01) and the myocardin-related transcription factors (MRTFs) A and B was observed in patients compared with controls (MRTF-A mRNA: twofold, p=0.028; MRTF-B mRNA: fourfold, p=0.011). miR-1 expression was associated with smoking history, lung function, fat-free mass index, 6 min walk distance and percentage of type 1 fibres. miR-133 and miR-206 were negatively correlated with daily physical activity. Insulin-like growth factor 1 mRNA was increased in the patients and miR-1 was negatively correlated with phosphorylation of the kinase Akt. Furthermore, the protein levels of histone deacetylase 4, another miR-1 target, were increased in the patients." target gene hsa-mir-133b Chronic Obstructive Pulmonary Disease 21998125 "A reduction in expression of miR-1 (2.5-fold, p=0.01) and the myocardin-related transcription factors (MRTFs) A and B was observed in patients compared with controls (MRTF-A mRNA: twofold, p=0.028; MRTF-B mRNA: fourfold, p=0.011). miR-1 expression was associated with smoking history, lung function, fat-free mass index, 6 min walk distance and percentage of type 1 fibres. miR-133 and miR-206 were negatively correlated with daily physical activity. Insulin-like growth factor 1 mRNA was increased in the patients and miR-1 was negatively correlated with phosphorylation of the kinase Akt. Furthermore, the protein levels of histone deacetylase 4, another miR-1 target, were increased in the patients." target gene hsa-mir-206 Chronic Obstructive Pulmonary Disease 21998125 "A reduction in expression of miR-1 (2.5-fold, p=0.01) and the myocardin-related transcription factors (MRTFs) A and B was observed in patients compared with controls (MRTF-A mRNA: twofold, p=0.028; MRTF-B mRNA: fourfold, p=0.011). miR-1 expression was associated with smoking history, lung function, fat-free mass index, 6 min walk distance and percentage of type 1 fibres. miR-133 and miR-206 were negatively correlated with daily physical activity. Insulin-like growth factor 1 mRNA was increased in the patients and miR-1 was negatively correlated with phosphorylation of the kinase Akt. Furthermore, the protein levels of histone deacetylase 4, another miR-1 target, were increased in the patients." target gene hsa-mir-29a Gastric Neoplasms 21998710 MiR-29a Inhibits Cell Proliferation and Induces Cell Cycle Arrest through the Downregulation of p42.3 in Human Gastric Cancer. target gene hsa-mir-21 Urinary Bladder Cancer 22001440 MiR-21 is involved in cervical squamous cell tumorigenesis and regulates CCL20. target gene hsa-mir-137 Intellectual Disability 22003227 "The patients displayed a significantly decreased expression of both precursor and mature miR-137 levels, as well as significantly increased expression of the validated downstream targets microphthalmia-associated transcription factor (MITF) and Enhancer of Zeste, Drosophila, Homologue 2 (EZH2), and the newly identified target Kruppel-like factor 4 (KLF4). The study also demonstrated significant enrichment of miR-137 at the synapses of cortical and hippocampal neurons, suggesting a role of miR-137 in regulating local synaptic protein synthesis machinery." target gene hsa-mir-126 Endometriosis 22012249 "The expression level of miR-126 was significantly downregulated in ECs versus EUs (p = 5.45E(-5)) in the experimental group and in EUs versus ENs (p = 0.019).miR-126 may play an initial role in the development and progression of EMs. Crk may be regulated by miR-126, and synergism between abnormal expressions may play an important role in the pathogenesis of EMs." target gene hsa-let-7a-1 Endometrial Neoplasms 22014978 "The activated estrogen receptor can suppress the expression of BAX by upregulating a group of microRNAs including hsa-let-7 family members and hsa-miR-27a, thereby promoting an increased BCL2/BAX ratio as well as enhanced survival and proliferation in the affected cells." target gene hsa-let-7a-2 Endometrial Neoplasms 22014978 "The activated estrogen receptor can suppress the expression of BAX by upregulating a group of microRNAs including hsa-let-7 family members and hsa-miR-27a, thereby promoting an increased BCL2/BAX ratio as well as enhanced survival and proliferation in the affected cells." target gene hsa-let-7a-3 Endometrial Neoplasms 22014978 "The activated estrogen receptor can suppress the expression of BAX by upregulating a group of microRNAs including hsa-let-7 family members and hsa-miR-27a, thereby promoting an increased BCL2/BAX ratio as well as enhanced survival and proliferation in the affected cells." target gene hsa-let-7b Endometrial Neoplasms 22014978 "The activated estrogen receptor can suppress the expression of BAX by upregulating a group of microRNAs including hsa-let-7 family members and hsa-miR-27a, thereby promoting an increased BCL2/BAX ratio as well as enhanced survival and proliferation in the affected cells." target gene hsa-let-7c Endometrial Neoplasms 22014978 "The activated estrogen receptor can suppress the expression of BAX by upregulating a group of microRNAs including hsa-let-7 family members and hsa-miR-27a, thereby promoting an increased BCL2/BAX ratio as well as enhanced survival and proliferation in the affected cells." target gene hsa-let-7d Endometrial Neoplasms 22014978 "The activated estrogen receptor can suppress the expression of BAX by upregulating a group of microRNAs including hsa-let-7 family members and hsa-miR-27a, thereby promoting an increased BCL2/BAX ratio as well as enhanced survival and proliferation in the affected cells." target gene hsa-let-7e Endometrial Neoplasms 22014978 "The activated estrogen receptor can suppress the expression of BAX by upregulating a group of microRNAs including hsa-let-7 family members and hsa-miR-27a, thereby promoting an increased BCL2/BAX ratio as well as enhanced survival and proliferation in the affected cells." target gene hsa-let-7f-1 Endometrial Neoplasms 22014978 "The activated estrogen receptor can suppress the expression of BAX by upregulating a group of microRNAs including hsa-let-7 family members and hsa-miR-27a, thereby promoting an increased BCL2/BAX ratio as well as enhanced survival and proliferation in the affected cells." target gene hsa-let-7f-2 Endometrial Neoplasms 22014978 "The activated estrogen receptor can suppress the expression of BAX by upregulating a group of microRNAs including hsa-let-7 family members and hsa-miR-27a, thereby promoting an increased BCL2/BAX ratio as well as enhanced survival and proliferation in the affected cells." target gene hsa-let-7g Endometrial Neoplasms 22014978 "The activated estrogen receptor can suppress the expression of BAX by upregulating a group of microRNAs including hsa-let-7 family members and hsa-miR-27a, thereby promoting an increased BCL2/BAX ratio as well as enhanced survival and proliferation in the affected cells." target gene hsa-let-7i Endometrial Neoplasms 22014978 "The activated estrogen receptor can suppress the expression of BAX by upregulating a group of microRNAs including hsa-let-7 family members and hsa-miR-27a, thereby promoting an increased BCL2/BAX ratio as well as enhanced survival and proliferation in the affected cells." target gene hsa-mir-200c Endometrial Neoplasms 22015043 "We found that miR-200c expression was increased in endometrial carcinoma compared with normal endometrial tissues. Anti-miR or pre-miR-200c could regulate cell survival, proliferation, and apoptosis and affect cytotoxicity in endometrial cancer cells. Through mRNA microarray analysis, we found that miR-200c inhibits the expression of BRD7, which was recently reported as a potential tumor suppressor gene. MiR-200c regulated the translocation of §Ø©ãcatenin from the cytoplasm to the nucleus via inhibition of BRD7, resulting in increased expression of its transcriptional target genes, cyclinD1 and c-myc." target gene hsa-let-7a-1 Colorectal Carcinoma 22018986 NIRF is frequently upregulated in colorectal cancer and its oncogenicity can be suppressed by let-7a microRNA. target gene hsa-let-7a-2 Colorectal Carcinoma 22018986 NIRF is frequently upregulated in colorectal cancer and its oncogenicity can be suppressed by let-7a microRNA. target gene hsa-let-7a-3 Colorectal Carcinoma 22018986 NIRF is frequently upregulated in colorectal cancer and its oncogenicity can be suppressed by let-7a microRNA. target gene hsa-mir-148b Colorectal Carcinoma 22020560 MicroRNA-148b suppresses cell growth by targeting cholecystokinin-2 receptor in colorectal cancer. target gene hsa-mir-146a Gastric Neoplasms 22020746 Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis. target gene hsa-mir-30c-1 Ovarian Neoplasms 22024689 MicroRNA-30c-2* expressed in ovarian cancer cells suppresses growth factor induced cellular proliferation and downregulates the oncogene BCL9. target gene hsa-mir-30c-2 Ovarian Neoplasms 22024689 MicroRNA-30c-2* expressed in ovarian cancer cells suppresses growth factor induced cellular proliferation and downregulates the oncogene BCL9. target gene hsa-mir-150 "Carcinoma, Hepatocellular" 22025269 microRNA-150 inhibits human CD133-positive liver cancer stem cells through negative regulation of the transcription factor c-Myb. target gene hsa-mir-155 Lung Neoplasms 22027557 "Hypoxic conditions induce miR-155 expression in lung cancer cells and trigger a corresponding decrease in a validated target, FOXO3A. Furthermore, we find that increased levels of miR-155 radioprotects lung cancer cells, while inhibition of miR-155 radiosensitizes these cells. Moreover, we reveal a therapeutically important link between miR-155 expression, hypoxia, and irradiation by demonstrating that anti-miR-155 molecules also sensitize hypoxic lung cancer cells to irradiation. Our study helps explain how miR-155 becomes elevated in lung cancers, which contain extensive hypoxic microenvironments, and demonstrates that inhibition of miR-155 may have important therapeutic potential as a means to radiosensitize hypoxic lung cancer cells." target gene hsa-mir-194-1 Colorectal Carcinoma 22028325 p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancers. target gene hsa-mir-194-2 Colorectal Carcinoma 22028325 p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancers. target gene hsa-mir-375 Head And Neck Neoplasms 22031094 "MiR-375 expression was significantly reduced (p=0.01), and conversely, MTDH was significantly increased (p=0.0001) in NPC samples. Quantitative RT-PCR, western blots and luciferase assays corroborated MTDH as a target of miR-375. Re-expression of miR-375 and siRNA knock-down of MTDH both decreased cell viability and clonogenic survival, cell migration/invasion, as well as in vivo tumour formation. NPC patients whose tumours expressed high levels of MTDH experienced significantly lower survival, and in particular, higher distant relapse rates (5-year distant relapse rates: 26% vs. 5%; p=0.005)." target gene hsa-mir-506 Colon Neoplasms 22036718 MicroRNA 506 regulates expression of PPAR alpha in hydroxycamptothecin-resistant human colon cancer cells. target gene hsa-mir-23a Vascular Disease [unspecific] 22038739 Our results suggest that miR-23a may be involved in TNF-¦Á-induced endothelial cell apoptosis through regulation of the caspase-7 and serine/threonine kinase?4-caspase-3 pathways. target gene hsa-mir-150 Myocardial Infarction 22039399 microRNA-150 regulates mobilization and migration of bone marrow-derived mononuclear cells by targeting Cxcr4. target gene hsa-mir-7-1 Glioblastoma 22040413 MicroRNA-7 regulates glioblastoma cell invasion via targeting focal adhesion kinase expression. target gene hsa-mir-7-2 Glioblastoma 22040413 MicroRNA-7 regulates glioblastoma cell invasion via targeting focal adhesion kinase expression. target gene hsa-mir-7-3 Glioblastoma 22040413 MicroRNA-7 regulates glioblastoma cell invasion via targeting focal adhesion kinase expression. target gene hsa-mir-494 Gastrointestinal Neoplasms 22042971 MicroRNA-494 Downregulates KIT and Inhibits Gastrointestinal Stromal Tumor Cell Proliferation. target gene hsa-mir-1 Heart Failure 22045061 MicroRNA-1 represses Cx43 expression in viral myocarditis. target gene hsa-mir-125b-1 Huntington Disease 22048026 "Micro RNA -214,-150,-146a and-125b target Huntingtin gene." target gene hsa-mir-125b-2 Huntington Disease 22048026 "Micro RNA -214,-150,-146a and-125b target Huntingtin gene." target gene hsa-mir-146a Huntington Disease 22048026 "Micro RNA -214,-150,-146a and-125b target Huntingtin gene." target gene hsa-mir-150 Huntington Disease 22048026 "Micro RNA -214,-150,-146a and-125b target Huntingtin gene." target gene hsa-mir-214 Huntington Disease 22048026 "Micro RNA -214,-150,-146a and-125b target Huntingtin gene." target gene hsa-mir-375 "Carcinoma, Hepatocellular" 22056881 MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo. target gene hsa-mir-493 Urinary Bladder Cancer 22057916 Tumor suppressor microRNA-493 decreases cell motility and migration ability in human bladder cancer cells by down-regulating RhoC and FZD4. target gene hsa-mir-1-1 Nasopharyngeal Neoplasms 22059741 MicroRNA-1 induces apoptosis by targeting prothymosin alpha in nasopharyngeal carcinoma cells. target gene hsa-mir-1-2 Nasopharyngeal Neoplasms 22059741 MicroRNA-1 induces apoptosis by targeting prothymosin alpha in nasopharyngeal carcinoma cells. target gene hsa-mir-126 Pancreatic Neoplasms 22064652 MiR-126 acts as a tumor suppressor in pancreatic cancer cells via the regulation of ADAM9. target gene hsa-mir-1-1 Prostate Neoplasms 22068816 Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. target gene hsa-mir-1-2 Prostate Neoplasms 22068816 Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. target gene hsa-mir-133a-1 Prostate Neoplasms 22068816 Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. target gene hsa-mir-133a-2 Prostate Neoplasms 22068816 Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. target gene hsa-mir-433 Ovarian Neoplasms 22069160 "MAD2 protein expression levels were downregulated in pre-miR-433 transfected A2780 cells. Secondly, Pre-miR-433 suppressed the activity of a reporter construct containing the 3'-UTR of MAD2. Thirdly, blocking miR-433 binding to the MAD2 3'UTR protected MAD2 from miR-433 induced protein downregulation. Importantly, reduced MAD2 protein expression in pre-miR-433 transfected A2780 cells rendered these cells less sensitive to paclitaxel. In conclusion, loss of MAD2 protein expression results in increased resistance to paclitaxel in EOC cells." target gene hsa-mir-885 "Squamous Cell Carcinoma, Head and Neck" 22071691 "miR-885-3p modulated the cisplatin-induced TP53-dependent mitochondrial apoptosis by up regulation of MDM4 levels and down regulation of BCL2 levels in mitochondria. Altogether, our results support the notion that miR-885-3p might contribute in regulation of cell viability, apoptosis and/or autophagy in squamous cell carcinoma cells upon cisplatin exposure." target gene hsa-mir-21 Colon Neoplasms 22072622 MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGFbetaR2) in colon cancer cells. target gene hsa-mir-221 Glioma 22075712 Downregulation of miR-221/222 sensitizes glioma cells to temozolomide by regulating apoptosis independently of p53 status. target gene hsa-mir-222 Glioma 22075712 Downregulation of miR-221/222 sensitizes glioma cells to temozolomide by regulating apoptosis independently of p53 status. target gene hsa-mir-25 Ovarian Neoplasms 22076535 MiR-25 regulates apoptosis by targeting Bim in human ovarian cancer. target gene hsa-mir-155 Human Immunodeficiency Virus Infection 22080513 "microRNA-223 levels were significantly enriched in HIV-1-infected CD4(+)CD8(-) PBMCs, microRNA-29a/b, microRNA-155 and microRNA-21 levels were significantly reduced. Based on the potential for microRNA binding sites in a conserved sequence of the Nef-3'-LTR, several host microRNAs potentially could affect HIV-1 gene expression. Among those microRNAs, the microRNA-29 family has seed complementarity in the HIV-1 3'-UTR, but the potential suppressive effect of microRNA-29 on HIV-1 is severely blocked by the secondary structure of the target region." target gene hsa-mir-21 Human Immunodeficiency Virus Infection 22080513 "microRNA-223 levels were significantly enriched in HIV-1-infected CD4(+)CD8(-) PBMCs, microRNA-29a/b, microRNA-155 and microRNA-21 levels were significantly reduced. Based on the potential for microRNA binding sites in a conserved sequence of the Nef-3'-LTR, several host microRNAs potentially could affect HIV-1 gene expression. Among those microRNAs, the microRNA-29 family has seed complementarity in the HIV-1 3'-UTR, but the potential suppressive effect of microRNA-29 on HIV-1 is severely blocked by the secondary structure of the target region." target gene hsa-mir-223 Human Immunodeficiency Virus Infection 22080513 "microRNA-223 levels were significantly enriched in HIV-1-infected CD4(+)CD8(-) PBMCs, microRNA-29a/b, microRNA-155 and microRNA-21 levels were significantly reduced. Based on the potential for microRNA binding sites in a conserved sequence of the Nef-3'-LTR, several host microRNAs potentially could affect HIV-1 gene expression. Among those microRNAs, the microRNA-29 family has seed complementarity in the HIV-1 3'-UTR, but the potential suppressive effect of microRNA-29 on HIV-1 is severely blocked by the secondary structure of the target region." target gene hsa-mir-29a Human Immunodeficiency Virus Infection 22080513 "microRNA-223 levels were significantly enriched in HIV-1-infected CD4(+)CD8(-) PBMCs, microRNA-29a/b, microRNA-155 and microRNA-21 levels were significantly reduced. Based on the potential for microRNA binding sites in a conserved sequence of the Nef-3'-LTR, several host microRNAs potentially could affect HIV-1 gene expression. Among those microRNAs, the microRNA-29 family has seed complementarity in the HIV-1 3'-UTR, but the potential suppressive effect of microRNA-29 on HIV-1 is severely blocked by the secondary structure of the target region." target gene hsa-mir-124-1 Breast Neoplasms 22085528 miR-124 suppresses multiple steps of breast cancer metastasis by targeting a cohort of pro-metastatic genes in vitro. target gene hsa-mir-124-2 Breast Neoplasms 22085528 miR-124 suppresses multiple steps of breast cancer metastasis by targeting a cohort of pro-metastatic genes in vitro. target gene hsa-mir-124-3 Breast Neoplasms 22085528 miR-124 suppresses multiple steps of breast cancer metastasis by targeting a cohort of pro-metastatic genes in vitro. target gene hsa-mir-31 Glioma 22089331 Human miR-31 targets radixin and inhibits migration and invasion of glioma cells. target gene hsa-mir-199a-1 "Carcinoma, Renal Cell" 22093618 Re-expression of miR-199a suppresses renal cancer cell proliferation and survival by targeting GSK-3 target gene hsa-mir-145 Glioblastoma 22098779 "The expression of miR145 (a tumor-suppressive miRNA) is inversely correlated with the levels of Oct4 and Sox2 in GBM-CD133(+) cells and malignant glioma specimens.miR145 negatively regulates GBM tumorigenesis by targeting Oct4 and Sox2 in GBM-CD133(+). Using polyurethane-short branch polyethylenimine (PU-PEI) as a therapeutic-delivery vehicle, PU-PEI-mediated miR145 delivery to GBM-CD133(+) significantly inhibited their tumorigenic and CSC-like abilities and facilitated their differentiation into CD133(-)-non-CSCs. Furthermore, PU-PEI-miR145-treated GBM-CD133(+) effectively suppressed the expression of drug-resistance and anti-apoptotic genes and increased the sensitivity of the cells to radiation and temozolomide. Finally, the in vivo delivery of PU-PEI-miR145 alone significantly suppressed tumorigenesis with stemness, and synergistically improved the survival rate when used in combination with radiotherapy and temozolomide in orthotopic GBM-CD133(+)-transplanted immunocompromised mice. Therefore, PU-PEI-miR145 is a novel therapeutic approach for malignant brain tumors." target gene hsa-mir-21 Colorectal Carcinoma 22099878 miR-21 functionally interacts with the 3'UTR of chemokine CCL20 and down-regulates CCL20 expression in miR-21 transfected colorectal cancer cells. target gene hsa-mir-520e "Carcinoma, Hepatocellular" 22105365 MicroRNA-520e suppresses growth of hepatoma cells by targeting the NF-kB-inducing kinase (NIK). target gene hsa-mir-19a Rheumatoid Arthritis 22105995 "TLR2 Expression Is Regulated by MicroRNA miR-19 in Rheumatoid Fibroblast-like Synoviocytes.Downregulation of miR-19b and miR-19a, which belongs to the same cluster, was confirmed by real-time quantitative PCR. Transfection of RA FLS with miR-19a/b mimics decreased TLR2 protein expression. In parallel, we found that both IL-6 and matrix metalloproteinase 3 secretion was significantly downregulated in activated FLS transfected with either mimic. Moreover, using a luciferase assay, we showed that miR-19a/b directly target Tlr2 mRNA." target gene hsa-mir-19b-1 Rheumatoid Arthritis 22105995 "TLR2 Expression Is Regulated by MicroRNA miR-19 in Rheumatoid Fibroblast-like Synoviocytes.Downregulation of miR-19b and miR-19a, which belongs to the same cluster, was confirmed by real-time quantitative PCR. Transfection of RA FLS with miR-19a/b mimics decreased TLR2 protein expression. In parallel, we found that both IL-6 and matrix metalloproteinase 3 secretion was significantly downregulated in activated FLS transfected with either mimic. Moreover, using a luciferase assay, we showed that miR-19a/b directly target Tlr2 mRNA." target gene hsa-mir-19b-2 Rheumatoid Arthritis 22105995 "TLR2 Expression Is Regulated by MicroRNA miR-19 in Rheumatoid Fibroblast-like Synoviocytes.Downregulation of miR-19b and miR-19a, which belongs to the same cluster, was confirmed by real-time quantitative PCR. Transfection of RA FLS with miR-19a/b mimics decreased TLR2 protein expression. In parallel, we found that both IL-6 and matrix metalloproteinase 3 secretion was significantly downregulated in activated FLS transfected with either mimic. Moreover, using a luciferase assay, we showed that miR-19a/b directly target Tlr2 mRNA." target gene hsa-mir-143 Urinary Bladder Cancer 22108519 The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer. target gene hsa-mir-145 Urinary Bladder Cancer 22108519 The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer. target gene hsa-mir-206 Laryngeal Neoplasms 22110210 Down-regulation of MiR-206 Promotes Proliferation and Invasion of Laryngeal Cancer by Regulating VEGF Expression. target gene hsa-mir-34b Breast Neoplasms 22113133 "In this study, we identified one such estrogen down-regulated microRNA, miR-34b, as an onco-suppressor that targets cyclin D1 and JAG-1 (jagged 1) in a ER-positive/wild-type p53 breast cancer cell line (MCF-7) as well as in ovarian and endometrial cells," target gene hsa-mir-17 "Lymphoma, Mantle-Cell" 22116552 The miRNA-17-92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. target gene hsa-mir-18a "Lymphoma, Mantle-Cell" 22116552 The miRNA-17-92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. target gene hsa-mir-19a "Lymphoma, Mantle-Cell" 22116552 The miRNA-17-92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. target gene hsa-mir-19b-1 "Lymphoma, Mantle-Cell" 22116552 The miRNA-17-92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. target gene hsa-mir-20a "Lymphoma, Mantle-Cell" 22116552 The miRNA-17-92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. target gene hsa-mir-92a-1 "Lymphoma, Mantle-Cell" 22116552 The miRNA-17-92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. target gene hsa-mir-378a Cardiovascular Diseases [unspecific] 22119805 Overexpression of microRNA-378 attenuates ischemia-induced apoptosis by inhibiting caspase-3 expression in cardiac myocytes. target gene hsa-mir-100 Lung Neoplasms 22120675 MiR-100 Resensitizes Docetaxel-Resistant Human Lung Adenocarcinoma Cells (SPC-A1) to Docetaxel by Targeting Plk1. target gene hsa-mir-27b Neuroblastoma 22120719 "MiR-27b targets PPARgamma to inhibit growth, tumor progression and the inflammatory response in neuroblastoma cells." target gene hsa-mir-1915 Colorectal Carcinoma 22121083 miR-1915 inhibits Bcl-2 to modulate multidrug resistance by increasing drug-sensitivity in human colorectal carcinoma cells. target gene hsa-mir-221 Colon Neoplasms 22126772 MicroRNA-221 promotes colon carcinoma cell proliferation in vitro by inhibiting CDKN1C/p57 expression. target gene hsa-let-7c Prostate Neoplasms 22128178 MicroRNA let-7c suppresses androgen receptor expression and activity via regulation of Myc expression in prostate cancer cells. target gene hsa-mir-21 Melanoma 22130252 "Increased levels of microRNA-21 expression were shown from dysplastic nevi to primary cutaneous melanomas to melanoma metastases. Moreover, high miR-21 expression was found to be correlated with Breslow thickness and advanced clinical stage. Patients with high microRNA-21 expression showed shorter 5-year disease-free or overall survival than those with low microRNA-21 expression. Furthermore, multivariate regression analysis showed that the status of microRNA-21 expression was an independent prognostic factor for overall survival of patients. Antisense-mediated microRNA-21 inhibition could significantly suppress growth, increase apoptosis and enhance chemo- or radiosensitivity of human cutaneous melanoma cells by inducing the increased Bax/Bcl-2 ratio. Thus, the status of microRNA-21 might be an independent prognostic factor for patients with cutaneous melanoma, and microRNA-21 has the potential of being a novel molecular target for the treatment of human cutaneous melanoma." target gene hsa-mir-17 Colorectal Carcinoma 22132820 "Up-regulated miR-17 promotes cell proliferation, tumor growth and cell cycle progression by targeting RND3 tumor suppressor gene in colorectal carcinoma." target gene hsa-mir-330 Colon Neoplasms 22132977 "Expression of miR-330 in various colon and lung cancer cell lines, as measured by QRT-PCR, varied five-fold between samples and correlated with in-vitro gemcitabine resistance (R = 0.82, p = 0.04). Exposure to gemcitabine also appeared to influence miR-330 levels in these cell lines. Furthermore, in our cell line panel, miR-330 expression negatively correlated with dCK mRNA expression (R = 0.74), suggesting a role of miR-330 in post-transcriptional regulation of dCK." target gene hsa-mir-330 Lung Neoplasms 22132977 "Expression of miR-330 in various colon and lung cancer cell lines, as measured by QRT-PCR, varied five-fold between samples and correlated with in-vitro gemcitabine resistance (R = 0.82, p = 0.04). Exposure to gemcitabine also appeared to influence miR-330 levels in these cell lines. Furthermore, in our cell line panel, miR-330 expression negatively correlated with dCK mRNA expression (R = 0.74), suggesting a role of miR-330 in post-transcriptional regulation of dCK." target gene hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 22133358 miR-15a and miR-16-1 inhibit the proliferation of leukemic cells by down-regulating WT1 protein level. target gene hsa-mir-15a "Leukemia, Myeloid, Acute" 22133358 miR-15a and miR-16-1 inhibit the proliferation of leukemic cells by down-regulating WT1 protein level. target gene hsa-mir-15a Multiple Myeloma 22133358 miR-15a and miR-16-1 inhibit the proliferation of leukemic cells by down-regulating WT1 protein level. target gene hsa-mir-320a Colorectal Carcinoma 22134529 microRNA-320a inhibits tumor invasion by targeting neuropilin 1 and is associated with liver metastasis in colorectal cancer. target gene hsa-mir-24-1 Laryngeal Neoplasms 22139384 miR-24 functions as a tumor suppressor in Hep2 laryngeal carcinoma cells partly through down-regulation of the S100A8 protein. target gene hsa-mir-24-2 Laryngeal Neoplasms 22139384 miR-24 functions as a tumor suppressor in Hep2 laryngeal carcinoma cells partly through down-regulation of the S100A8 protein. target gene hsa-mir-200b Lung Neoplasms 22139708 MicroRNA-200b reverses chemoresistance of docetaxel-resistant human lung adenocarcinoma cells by targeting E2F3. target gene hsa-mir-125b-1 "Leukemia, B-Cell" 22139839 MiR-125b and miR-155 contribute to BCL2 repression and proliferation in response to CD40 ligand (CD154) in human leukemic B-cells. target gene hsa-mir-125b-2 "Leukemia, B-Cell" 22139839 MiR-125b and miR-155 contribute to BCL2 repression and proliferation in response to CD40 ligand (CD154) in human leukemic B-cells. target gene hsa-mir-155 "Leukemia, B-Cell" 22139839 MiR-125b and miR-155 contribute to BCL2 repression and proliferation in response to CD40 ligand (CD154) in human leukemic B-cells. target gene hsa-mir-210 "Carcinoma, Hepatocellular" 22144109 Hypoxia-inducible MicroRNA-210 augments the metastatic potential of tumor cells by targeting vacuole membrane protein 1 in hepatocellular carcinoma. target gene hsa-mir-200c Breast Neoplasms 22144583 MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F. target gene hsa-mir-421 Biliary Tract Neoplasms 22146319 MicroRNA-421 functions as an oncogenic miRNA in biliary tract cancer through down-regulating farnesoid X receptor expression. target gene hsa-mir-23b Pain 22149086 MiR23b Ameliorates Neuropathic Pain in Spinal Cord by Silencing NOX4. target gene hsa-mir-221 "Carcinoma, Hepatocellular" 22152314 MiR-221 contributes to the growth of hepatocellular carcinoma cells and miR-221 inhibition can induce cell apoptosis. miR-221 has the potential to become one of the new molecular targets for liver cancer therapy. target gene hsa-let-7a "Carcinoma, Renal Cell" 22155254 Our results suggest for the first time that let-7a acts as a tumor suppressor in RCC cell lines by down-regulating c-myc and c-myc target genes. target gene hsa-mir-103a-1 Lung Neoplasms 22157681 "Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC)." target gene hsa-mir-103a-2 Lung Neoplasms 22157681 "Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC)." target gene hsa-mir-103b-1 Lung Neoplasms 22157681 "Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC)." target gene hsa-mir-103b-2 Lung Neoplasms 22157681 "Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC)." target gene hsa-mir-203 Lung Neoplasms 22157681 "Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC)." target gene hsa-mir-221 Lung Neoplasms 22157681 "Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC)." target gene hsa-mir-222 Lung Neoplasms 22157681 "Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC)." target gene hsa-mir-30b Lung Neoplasms 22157681 "Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC)." target gene hsa-mir-30c-1 Lung Neoplasms 22157681 "Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC)." target gene hsa-mir-30c-2 Lung Neoplasms 22157681 "Here we report that miR-30b, miR-30c, miR-221 and miR-222 are modulated by both epidermal growth factor (EGF) and MET receptors, whereas miR-103 and miR-203 are controlled only by MET. We showed that these miRNAs have important roles in gefitinib-induced apoptosis and epithelial-mesenchymal transition of NSCLC cells in vitro and in vivo by inhibiting the expression of the genes encoding BCL2-like 11 (BIM), apoptotic peptidase activating factor 1 (APAF-1), protein kinase C ? (PKC-?) and sarcoma viral oncogene homolog (SRC)." target gene hsa-mir-30a Breast Neoplasms 22157765 MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagy. target gene hsa-mir-30a "Carcinoma, Hepatocellular" 22157765 MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagy. target gene hsa-mir-30a Ovarian Neoplasms 22157765 MicroRNA-30a sensitizes tumor cells to cis-platinum via suppressing beclin 1-mediated autophagy. target gene hsa-mir-373 Breast Neoplasms 22158050 MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kB and TGF-beta signaling pathways. target gene hsa-mir-520a Breast Neoplasms 22158050 MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kB and TGF-beta signaling pathways. target gene hsa-mir-520b Breast Neoplasms 22158050 MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kB and TGF-beta signaling pathways. target gene hsa-mir-520c Breast Neoplasms 22158050 MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kB and TGF-beta signaling pathways. target gene hsa-mir-520d Breast Neoplasms 22158050 MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kB and TGF-beta signaling pathways. target gene hsa-mir-1245a Breast Neoplasms 22158906 Upregulation of miR-1245 by c-myc targets BRCA2 and impairs DNA repair. target gene hsa-mir-1245b Breast Neoplasms 22158906 Upregulation of miR-1245 by c-myc targets BRCA2 and impairs DNA repair. target gene hsa-mir-34a "Carcinoma, Renal Cell" 22159222 MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma. target gene hsa-mir-205 Glioblastoma 22159356 MicroRNA-205 functions as a tumor suppressor in human glioblastoma cells by targeting VEGF-A. target gene hsa-mir-143 Urinary Bladder Cancer 22160209 miR-143 is downregulated in cervical cancer and promotes apoptosis and inhibits tumor formation by targeting Bcl-2. target gene hsa-mir-34a Neuroblastoma 22160687 "Notably, the axis TAp73/miR-34a/synaptotagmin-1 is conserved in brains from Alzheimer's patients. " target gene hsa-mir-146a Prostate Neoplasms 22161865 MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castration-resistant prostate cancer. target gene hsa-mir-146a "Carcinoma, Hepatocellular" 22167321 "The authors demonstrate that miR-146a, miR-99b and miR-205, induced in HCC1937 BRCA1-expressing cells, bind and regulate TRAF2 gene. In addition, re-expression of miR-146a, miR-99b or miR-205 in HCC1937 BRCA1-null cells was sufficient to modulate NF-§Ø¨mB activity." target gene hsa-mir-205 "Carcinoma, Hepatocellular" 22167321 "The authors demonstrate that miR-146a, miR-99b and miR-205, induced in HCC1937 BRCA1-expressing cells, bind and regulate TRAF2 gene. In addition, re-expression of miR-146a, miR-99b or miR-205 in HCC1937 BRCA1-null cells was sufficient to modulate NF-§Ø¨mB activity." target gene hsa-mir-99b "Carcinoma, Hepatocellular" 22167321 "The authors demonstrate that miR-146a, miR-99b and miR-205, induced in HCC1937 BRCA1-expressing cells, bind and regulate TRAF2 gene. In addition, re-expression of miR-146a, miR-99b or miR-205 in HCC1937 BRCA1-null cells was sufficient to modulate NF-§Ø¨mB activity." target gene hsa-mir-21 Ovarian Neoplasms 22176994 miR-21 might play an important role in the proliferation and apoptosis of ovarian epithelial carcinoma cells through negatively control the expression of PDCD4. target gene hsa-mir-1-1 Urinary Bladder Cancer 22178073 Tumor suppressive microRNA-1 mediated novel apoptosis pathways through direct inhibition of splicing factor serine/arginine-rich 9 (SRSF9/SRp30c) in bladder cancer. target gene hsa-mir-1-2 Urinary Bladder Cancer 22178073 Tumor suppressive microRNA-1 mediated novel apoptosis pathways through direct inhibition of splicing factor serine/arginine-rich 9 (SRSF9/SRp30c) in bladder cancer. target gene hsa-mir-124-1 Alzheimer Disease 22178568 The miR-124 regulates the expression of BACE1/-secretase correlated with cell death in Alzheimer's disease. target gene hsa-mir-124-2 Alzheimer Disease 22178568 The miR-124 regulates the expression of BACE1/-secretase correlated with cell death in Alzheimer's disease. target gene hsa-mir-124-3 Alzheimer Disease 22178568 The miR-124 regulates the expression of BACE1/-secretase correlated with cell death in Alzheimer's disease. target gene hsa-mir-320a Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. target gene hsa-mir-320b-1 Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. target gene hsa-mir-320b-2 Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. target gene hsa-mir-320c-1 Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. target gene hsa-mir-320c-2 Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. target gene hsa-mir-320d-1 Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. target gene hsa-mir-320d-2 Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. target gene hsa-mir-320e Breast Neoplasms 22179046 Expression of the Pten-miR-320-Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients. This work reveals miR-320 as a critical component of the Pten tumour-suppressor axis that acts in stromal fibroblasts to reprogramme the tumour microenvironment and curtail tumour progression. target gene hsa-mir-451a Glioma 22179124 MicroRNA miR-451 downregulates the PI3K/AKT pathway through CAB39 in human glioma. target gene hsa-mir-409 Gastric Neoplasms 22179828 MicroRNA-409 suppresses tumour cell invasion and metastasis by directly targeting radixin in gastric cancers. target gene hsa-mir-137 Schizophrenia 22182936 "Schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 are miR-137 targets." target gene hsa-mir-200a Lymphoma 22183793 "MicroRNA-200 is commonly repressed in conjunctival MALT lymphoma, and targets cyclin E2." target gene hsa-mir-200b Lymphoma 22183793 "MicroRNA-200 is commonly repressed in conjunctival MALT lymphoma, and targets cyclin E2." target gene hsa-mir-200c Lymphoma 22183793 "MicroRNA-200 is commonly repressed in conjunctival MALT lymphoma, and targets cyclin E2." target gene hsa-mir-365a Lung Neoplasms 22185756 MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1. target gene hsa-mir-365b Lung Neoplasms 22185756 MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1. target gene hsa-mir-20a Osteosarcoma 22186140 miR-20a increases the metastatic potential of osteosarcoma cells by regulating Fas expression. target gene hsa-mir-34a Colon Neoplasms 22198213 MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1. target gene hsa-mir-210 Preeclampsia 22203747 Hydroxysteroid (17-beta) Dehydrogenase 1 Is Dysregulated by Mir-210 and Mir-518c That Are Aberrantly Expressed in Preeclamptic Placentas. target gene hsa-mir-518c Preeclampsia 22203747 Hydroxysteroid (17-beta) Dehydrogenase 1 Is Dysregulated by Mir-210 and Mir-518c That Are Aberrantly Expressed in Preeclamptic Placentas. target gene hsa-mir-181d Glioma 22207524 MiR-181d acts as a tumor suppressor in glioma by targeting K-ras and Bcl-2. target gene hsa-mir-203 Breast Neoplasms 22207897 Anti-miR-203 Upregulates SOCS3 Expression in Breast Cancer Cells and Enhances Cisplatin Chemosensitivity. target gene hsa-mir-195 Glioblastoma 22217655 MicroRNA-195 plays a tumor-suppressor role in human glioblastoma cells by targeting signaling pathways involved in cellular proliferation and invasion. target gene hsa-mir-1236 Inflammation 22223733 Mirtron MicroRNA-1236 Inhibits VEGFR-3 Signaling During Inflammatory Lymphangiogenesis. target gene hsa-mir-17 Schizophrenia 22228753 Expression of NPAS3 in the Human Cortex is regulated by miR-17 During Development and has Implications for Schizophrenia. target gene hsa-mir-7-1 "Carcinoma, Hepatocellular" 22234835 miR-7 inhibits tumor growth and metastasis by targeting the PI3K/AKT pathway in hepatocellular carcinoma. target gene hsa-mir-7-2 "Carcinoma, Hepatocellular" 22234835 miR-7 inhibits tumor growth and metastasis by targeting the PI3K/AKT pathway in hepatocellular carcinoma. target gene hsa-mir-7-3 "Carcinoma, Hepatocellular" 22234835 miR-7 inhibits tumor growth and metastasis by targeting the PI3K/AKT pathway in hepatocellular carcinoma. target gene hsa-mir-122 Lymphoma 22235305 miR-122 regulates p53/Akt signalling and the chemotherapy-induced apoptosis in cutaneous T-cell lymphoma. target gene hsa-mir-211 Colorectal Carcinoma 22235338 MicroRNA-211 expression promotes colorectal cancer cell growth in vitro and in vivo by targeting tumor suppressor CHD5. target gene hsa-mir-212 "Leukemia, Myeloid, Chronic" 22241070 ABCG2 protein was 7.2-fold elevated after long-term treatment with imatinib and decreased gradually at higher concentrations. miRNAs miR-212 and miR-328 were identified to correlate inversely with ABCG2 expression under these conditions. target gene hsa-mir-328 "Leukemia, Myeloid, Chronic" 22241070 ABCG2 protein was 7.2-fold elevated after long-term treatment with imatinib and decreased gradually at higher concentrations. miRNAs miR-212 and miR-328 were identified to correlate inversely with ABCG2 expression under these conditions. target gene hsa-mir-34a Laryngeal Neoplasms 22246523 MicroRNA-34a affects the occurrence of laryngeal squamous cell carcinoma by targeting the antiapoptotic gene survivin. target gene hsa-mir-663a Nasopharyngeal Neoplasms 22249270 "MiR-663, a microRNA targeting p21(WAF1/CIP1), promotes the proliferation and tumorigenesis of nasopharyngeal carcinoma." target gene hsa-mir-124-1 Medulloblastoma 22249617 hsa-mir-124a targeted 3'UTR of HMGA1 and negatively modulated the expression in MB cells. target gene hsa-let-7a-1 Breast Neoplasms 22251626 MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7. target gene hsa-let-7a-2 Breast Neoplasms 22251626 MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7. target gene hsa-let-7a-3 Breast Neoplasms 22251626 MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7. target gene hsa-let-7i Pancreatic Neoplasms 22261338 "The miRNAs, let-7i and miR-143 was found to target Ras, and forced re-expression of let-7i and miR-143 inhibited Ras activity, cell proliferation and colony formation in vitro." target gene hsa-mir-143 Pancreatic Neoplasms 22261338 "The miRNAs, let-7i and miR-143 was found to target Ras, and forced re-expression of let-7i and miR-143 inhibited Ras activity, cell proliferation and colony formation in vitro." target gene hsa-mir-31 Leukemia 22264793 Polycomb-mediated loss of miR-31 activates NIK-dependent NF-kB pathway in adult T cell leukemia and other cancers. target gene hsa-mir-195 Urinary Bladder Cancer 22265971 MicroRNA-195-5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulating GLUT3 expression. target gene hsa-mir-449a Urinary Bladder Cancer 22266187 MicroRNA-449a acts as a tumor suppressor in human bladder cancer through the regulation of pocket proteins. target gene hsa-mir-133a-1 Head And Neck Neoplasms 22266319 Tumor suppressive microRNA-133a regulates novel targets: Moesin contributes to cancer cell proliferation and invasion in head and neck squamous cell carcinoma. target gene hsa-mir-32 Prostate Neoplasms 22266859 Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer. target gene hsa-mir-21 Gastric Neoplasms 22267008 microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN. target gene hsa-mir-21 Colorectal Carcinoma 22267128 Significant inverse correlations were demonstrated between PDCD4 and miR-21. target gene hsa-mir-223 Gastric Neoplasms 22270966 MicroRNA-223 functions as an oncogene in human gastric cancer by targeting FBXW7/hCdc4. target gene hsa-mir-221 Hypertrophy 22275134 MiR-221 promotes cardiac hypertrophy in vitro through the modulation of p27 expression. target gene hsa-mir-122 "Carcinoma, Hepatocellular" 22276989 MicroRNA-122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting Wnt/§Ø©ãcatenin pathway. target gene hsa-mir-181a-2 Leukemia 22285729 miR-181a sensitizes a multidrug-resistant leukemia cell line K562/A02 to daunorubicin by targeting BCL-2. target gene hsa-mir-21 Leprosy 22286305 MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy target gene hsa-mir-106b Breast Neoplasms 22286770 "The miR-106b-25 cluster targets Smad7, activates TGF-beta signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer." target gene hsa-mir-25 Breast Neoplasms 22286770 "The miR-106b-25 cluster targets Smad7, activates TGF-beta signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer." target gene hsa-mir-30a Colon Neoplasms 22287560 MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL. target gene hsa-mir-127 Inflammation 22287715 MicroRNA-127 Inhibits Lung Inflammation by Targeting IgG Fcgamma Receptor I. target gene hsa-mir-195 Urinary Bladder Cancer 22289176 Cyclin-dependent kinase 4 is a novel target in micoRNA-195-mediated cell cycle arrest in bladder cancer cells. target gene hsa-mir-29b-1 "Carcinoma, Lung, Non-Small-Cell" 22290228 miR-29b is an upstream molecule of PTEN. miR-29b regulates PTEN gene expression through downregulating Dnmts expression and subsequently induces hypomethylation in PTEN promoter. target gene hsa-mir-29b-2 "Carcinoma, Lung, Non-Small-Cell" 22290228 miR-29b is an upstream molecule of PTEN. miR-29b regulates PTEN gene expression through downregulating Dnmts expression and subsequently induces hypomethylation in PTEN promoter. target gene hsa-mir-125b-1 "Carcinoma, Hepatocellular" 22293115 MicroRNA-125b induces cancer cell apoptosis through suppression of Bcl-2 expression. target gene hsa-mir-125b-2 "Carcinoma, Hepatocellular" 22293115 MicroRNA-125b induces cancer cell apoptosis through suppression of Bcl-2 expression. target gene hsa-mir-10b Gastric Neoplasms 22293682 miR-10b promotes cell invasion through RhoC-AKT signaling pathway by targeting HOXD10 in gastric cancer. target gene hsa-mir-221 Glioblastoma 22294051 miR-221/222 is the regulator of Cx43 expression in human glioblastoma cells. target gene hsa-mir-1285-1 "Carcinoma, Renal Cell" 22294552 Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma. target gene hsa-mir-1285-2 "Carcinoma, Renal Cell" 22294552 Tumor suppressive microRNA-1285 regulates novel molecular targets: Aberrant expression and functional significance in renal cell carcinoma. target gene hsa-mir-125b-1 Alzheimer Disease 22302353 miR-125b and miR-146a regulate Complement Factor H (CFH) in Alzheimer's Disease (AD) Brain. target gene hsa-mir-125b-2 Alzheimer Disease 22302353 miR-125b and miR-146a regulate Complement Factor H (CFH) in Alzheimer's Disease (AD) Brain. target gene hsa-mir-146a Alzheimer Disease 22302353 miR-125b and miR-146a regulate Complement Factor H (CFH) in Alzheimer's Disease (AD) Brain. target gene hsa-mir-203 Laryngeal Neoplasms 22306317 MicroRNA-203 leads to G1 phase cell cycle arrest in laryngeal carcinoma cells by directly targeting survivin. target gene hsa-mir-205 Nasopharyngeal Neoplasms 22306986 MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN. target gene hsa-mir-125b-1 Breast Neoplasms 22307404 miR-125b targets ARID3B in breast cancer cells. target gene hsa-mir-125b-2 Breast Neoplasms 22307404 miR-125b targets ARID3B in breast cancer cells. target gene hsa-mir-155 "Carcinoma, Renal Cell" 22307849 microRNA-155 silencing inhibits proliferation and migration and induces apoptosis by upregulating BACH1 in renal cancer cells. target gene hsa-mir-9-1 "Lymphoma, Hodgkin" 22310293 Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo. target gene hsa-mir-9-2 "Lymphoma, Hodgkin" 22310293 Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo. target gene hsa-mir-9-3 "Lymphoma, Hodgkin" 22310293 Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo. target gene hsa-mir-135a-1 Gastric Neoplasms 22310976 MiR-135a targets JAK2 and inhibits gastric cancer cell proliferation. target gene hsa-mir-135a-2 Gastric Neoplasms 22310976 MiR-135a targets JAK2 and inhibits gastric cancer cell proliferation. target gene hsa-mir-499a "Carcinoma, Hepatocellular" 22311030 "hsa-mir-499 (rs3746444; adenine to guanine [C-T]) .Significant differences were found in frequency and distribution of the genotypes of miRNA-499 between the HCC and the control group. Compared with miRNA-499 T/T, the odds ratio (OR) of patients with miRNA-499 C/C for developing HCC was 3.630 (95% CI: 1.545-8.532), and OR for developing HBV-related HCC was 3.133 (95% CI: 1.248-7.861)." target gene hsa-mir-200b Gastric Neoplasms 22311119 "MicroRNA-200b Regulates Cell Proliferation, Invasion, and Migration by Directly Targeting ZEB2 in Gastric Carcinoma." target gene hsa-mir-141 Prostate Neoplasms 22314666 miR-141 modulates androgen receptor transcriptional activity in human prostate cancer cells through targeting the small heterodimer partner protein. target gene hsa-mir-23a "Carcinoma, Hepatocellular" 22318941 Stat3-mediated activation of miR-23a suppresses gluconeogenesis in hepatocellular carcinoma by downregulating G6PC and PGC-1§Ø©ã target gene hsa-mir-520b "Carcinoma, Hepatocellular" 22319632 MicroRNA-520b inhibits growth of hepatoma cells by targeting MEKK2 and cyclin D1. target gene hsa-mir-30c-1 "Carcinoma, Hepatocellular" 22320217 miR-30c-1* promotes natural killer cell cytotoxicity against human hepatoma cells by targeting the transcription factor HMBOX1. target gene hsa-mir-30c-2 "Carcinoma, Hepatocellular" 22320217 miR-30c-1* promotes natural killer cell cytotoxicity against human hepatoma cells by targeting the transcription factor HMBOX1. target gene hsa-mir-222 Gastric Neoplasms 22321642 Increased miR-222 in H. pylori-associated gastric cancer correlated with tumor progression by promoting cancer cell proliferation and targeting RECK. target gene hsa-mir-21 "Carcinoma, Hepatocellular" 22322403 miR-21 promotes migration and invasion by the miR-21-PDCD4-AP-1 feedback loop in human hepatocellular carcinoma. target gene hsa-mir-21 Colon Neoplasms 22322462 microRNA-21-mediated regulation of Sprouty2 protein expression enhances the cytotoxic effect of 5-fluorouracil and metformin in colon cancer cells. target gene hsa-mir-182 Gastric Neoplasms 22325466 MicroRNA-182 targets cAMP-responsive element-binding protein 1 and suppresses cell growth in human gastric adenocarcinoma. target gene hsa-mir-195 Breast Neoplasms 22328513 "miR-195, miR-24-2 and miR-365-2 act as negative regulators of BCL2 through direct binding to their respective binding sites in the 3' UTR of human BCL2 gene.over expression of these miRNAs not only caused an increase in apoptosis but also augmented the ap" target gene hsa-mir-24-2 Breast Neoplasms 22328513 "miR-195, miR-24-2 and miR-365-2 act as negative regulators of BCL2 through direct binding to their respective binding sites in the 3' UTR of human BCL2 gene.over expression of these miRNAs not only caused an increase in apoptosis but also augmented the ap" target gene hsa-mir-365b Breast Neoplasms 22328513 "miR-195, miR-24-2 and miR-365-2 act as negative regulators of BCL2 through direct binding to their respective binding sites in the 3' UTR of human BCL2 gene.over expression of these miRNAs not only caused an increase in apoptosis but also augmented the ap" target gene hsa-mir-106a Rhabdomyosarcoma 22330340 "Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma." target gene hsa-mir-1-1 Rhabdomyosarcoma 22330340 "Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma." target gene hsa-mir-1-2 Rhabdomyosarcoma 22330340 "Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma." target gene hsa-mir-29a Rhabdomyosarcoma 22330340 "Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma." target gene hsa-mir-29b-1 Rhabdomyosarcoma 22330340 "Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma." target gene hsa-mir-29b-2 Rhabdomyosarcoma 22330340 "Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma." target gene hsa-mir-29c Rhabdomyosarcoma 22330340 "Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma." target gene hsa-mir-29a Breast Neoplasms 22330642 "Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly," target gene hsa-mir-29b-1 Breast Neoplasms 22330642 "Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly," target gene hsa-mir-29b-2 Breast Neoplasms 22330642 "Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly," target gene hsa-mir-29c Breast Neoplasms 22330642 "Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly," target gene hsa-mir-513a-1 Breast Neoplasms 22330642 "Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly," target gene hsa-mir-513a-2 Breast Neoplasms 22330642 "Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly," target gene hsa-mir-124-1 Breast Neoplasms 22333974 "miR-124, miR-147 and miR-193a-3p are three novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer." target gene hsa-mir-124-2 Breast Neoplasms 22333974 "miR-124, miR-147 and miR-193a-3p are three novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer." target gene hsa-mir-124-3 Breast Neoplasms 22333974 "miR-124, miR-147 and miR-193a-3p are three novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer." target gene hsa-mir-147a Breast Neoplasms 22333974 "miR-124, miR-147 and miR-193a-3p are three novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer." target gene hsa-mir-193a Breast Neoplasms 22333974 "miR-124, miR-147 and miR-193a-3p are three novel tumor suppressors that co-target EGFR-driven cell-cycle network proteins and inhibit cell-cycle progression and proliferation in breast cancer." target gene hsa-mir-24-1 Retinoblastoma 22336108 Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development. target gene hsa-mir-24-2 Retinoblastoma 22336108 Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development. target gene hsa-mir-141 Aortic Stenosis 22336757 miRNA-141 is a novel regulator of BMP-2-mediated calcification in aortic stenosis. target gene hsa-mir-196a-1 Gastric Neoplasms 22343731 MiR-196a Is Up-regulated in Gastric cancer and Promotes Cell proliferation by Down-regulating p27kip1. target gene hsa-mir-196a-2 Gastric Neoplasms 22343731 MiR-196a Is Up-regulated in Gastric cancer and Promotes Cell proliferation by Down-regulating p27kip1. target gene hsa-mir-17 "Leukemia, Lymphocytic, Chronic, B-Cell" 22343732 The miR-17-92 family regulates the response to toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes. target gene hsa-mir-18a "Leukemia, Lymphocytic, Chronic, B-Cell" 22343732 The miR-17-92 family regulates the response to toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes. target gene hsa-mir-19a "Leukemia, Lymphocytic, Chronic, B-Cell" 22343732 The miR-17-92 family regulates the response to toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes. target gene hsa-mir-19b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 22343732 The miR-17-92 family regulates the response to toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes. target gene hsa-mir-20a "Leukemia, Lymphocytic, Chronic, B-Cell" 22343732 The miR-17-92 family regulates the response to toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes. target gene hsa-mir-92a-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 22343732 The miR-17-92 family regulates the response to toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes. target gene hsa-mir-127 Lung Neoplasms 22349807 "Bberrant expression of miRNAs such as miR-29ab, miR-183, miR-17-5p and miR-127-3P may play an important role in regulating the bio-behavior of TICs (tumor initiating cells)." target gene hsa-mir-17 Lung Neoplasms 22349807 "Bberrant expression of miRNAs such as miR-29ab, miR-183, miR-17-5p and miR-127-3P may play an important role in regulating the bio-behavior of TICs (tumor initiating cells)." target gene hsa-mir-183 Lung Neoplasms 22349807 "Bberrant expression of miRNAs such as miR-29ab, miR-183, miR-17-5p and miR-127-3P may play an important role in regulating the bio-behavior of TICs (tumor initiating cells)." target gene hsa-mir-29a Lung Neoplasms 22349807 "Bberrant expression of miRNAs such as miR-29ab, miR-183, miR-17-5p and miR-127-3P may play an important role in regulating the bio-behavior of TICs (tumor initiating cells)." target gene hsa-mir-29b-1 Lung Neoplasms 22349807 "Bberrant expression of miRNAs such as miR-29ab, miR-183, miR-17-5p and miR-127-3P may play an important role in regulating the bio-behavior of TICs (tumor initiating cells)." target gene hsa-mir-29b-2 Lung Neoplasms 22349807 "Bberrant expression of miRNAs such as miR-29ab, miR-183, miR-17-5p and miR-127-3P may play an important role in regulating the bio-behavior of TICs (tumor initiating cells)." target gene hsa-mir-155 Liposarcoma 22350414 MiR-155 is a liposarcoma oncogene that targets casein kinase-1§Ø©ãand enhances §Ø©ãcatenin signaling. target gene hsa-mir-130a "Leukemia, Lymphocytic, Chronic, B-Cell" 22350415 MicroRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells. target gene hsa-mir-21 Glioblastoma 22353043 Ursolic Acid Inhibits Proliferation and Induces Apoptosis in Human Glioblastoma Cell Lines U251 by Suppressing TGF-beta1/miR-21 /PDCD4 Pathway. target gene hsa-mir-196b Leukemia 22353710 miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia. target gene hsa-mir-143 Breast Neoplasms 22354042 A novel miR-155/miR-143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells. target gene hsa-mir-155 Breast Neoplasms 22354042 A novel miR-155/miR-143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells. target gene hsa-mir-203 Melanoma 22354972 Anti-oncogenic MicroRNA-203 Induces Senescence by Targeting E2F3 in Human Melanoma Cells. target gene hsa-mir-223 Melanoma 22356618 "MiRTrail identified several deregulated miRNAs that target deregulated mRNAs including miRNAs hsa-miR-23b and hsa-miR-223, which target the highest numbers of deregulated mRNAs and regulate the pathway ""basal cell carcinoma""." target gene hsa-mir-23b Melanoma 22356618 "MiRTrail identified several deregulated miRNAs that target deregulated mRNAs including miRNAs hsa-miR-23b and hsa-miR-223, which target the highest numbers of deregulated mRNAs and regulate the pathway ""basal cell carcinoma""." target gene hsa-mir-212 "Carcinoma, Lung, Non-Small-Cell" 22357618 MiR-212 displays Tumor Promoting properties in NSCLC Cells and targets the Hedgehog Pathway Receptor PTCH1. target gene hsa-mir-138-1 "Carcinoma, Hepatocellular" 22362728 MiR-138 induces cell cycle arrest by targeting cyclin D3 in hepatocellular carcinoma. target gene hsa-mir-138-2 "Carcinoma, Hepatocellular" 22362728 MiR-138 induces cell cycle arrest by targeting cyclin D3 in hepatocellular carcinoma. target gene hsa-mir-19a "Leukemia-Lymphoma, Adult T-Cell" 22362744 miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemia. target gene hsa-mir-19b-1 "Leukemia-Lymphoma, Adult T-Cell" 22362744 miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemia. target gene hsa-mir-19b-2 "Leukemia-Lymphoma, Adult T-Cell" 22362744 miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemia. target gene hsa-mir-34a Coronary Artery Disease 22364258 "MicroRNA-34a regulates the longevity-associated protein, SIRT1, in coronary artery disease." target gene hsa-mir-125b-1 Leukemia 22366319 Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A. target gene hsa-mir-125b-2 Leukemia 22366319 Oncomir miR-125b regulates hematopoiesis by targeting the gene Lin28A. target gene hsa-mir-34c "Carcinoma, Lung, Non-Small-Cell" 22370637 "The authors found a number of miRNAs (miR-17, miR-135, miR-520, miR-124-1, and miR-34c) that may rescue cell viability from caspase-8 activation. miR-34c-5p markedly increased resistance to paclitaxel-induced apoptosis. We demonstrate that Bmf (Bcl-2-modifying factor) is a target of miR-34c-5p, and that its silencing, together with that of c-myc, a known target of miR-34c-5p, contributes to resistance to apoptosis induced by paclitaxel through p53 downregulation." target gene hsa-mir-1-1 Prostate Neoplasms 22370643 "Mir-1 and miR-200 were reduced with progression of prostate adenocarcinoma, and we identify Slug as one of the phylogenetically conserved targets of these miRs. The authors demonstrate that SLUG is a direct repressor of miR-1 and miR-200 transcription. Th" target gene hsa-mir-1-2 Prostate Neoplasms 22370643 "Mir-1 and miR-200 were reduced with progression of prostate adenocarcinoma, and we identify Slug as one of the phylogenetically conserved targets of these miRs. The authors demonstrate that SLUG is a direct repressor of miR-1 and miR-200 transcription. Th" target gene hsa-mir-200a Prostate Neoplasms 22370643 "Mir-1 and miR-200 were reduced with progression of prostate adenocarcinoma, and we identify Slug as one of the phylogenetically conserved targets of these miRs. The authors demonstrate that SLUG is a direct repressor of miR-1 and miR-200 transcription. Th" target gene hsa-mir-200b Prostate Neoplasms 22370643 "Mir-1 and miR-200 were reduced with progression of prostate adenocarcinoma, and we identify Slug as one of the phylogenetically conserved targets of these miRs. The authors demonstrate that SLUG is a direct repressor of miR-1 and miR-200 transcription. Th" target gene hsa-mir-200c Prostate Neoplasms 22370643 "Mir-1 and miR-200 were reduced with progression of prostate adenocarcinoma, and we identify Slug as one of the phylogenetically conserved targets of these miRs. The authors demonstrate that SLUG is a direct repressor of miR-1 and miR-200 transcription. Th" target gene hsa-mir-301a "Carcinoma, Hepatocellular" 22373864 miR-301a Is a Candidate Oncogene that Targets the Homeobox Gene Gax in Human Hepatocellular Carcinoma. target gene hsa-mir-15b Liver Failure 22374434 miR-15b and miR-16 regulate TNF mediated hepatocyte apoptosis via BCL2 in acute liver failure. target gene hsa-mir-16-1 Liver Failure 22374434 miR-15b and miR-16 regulate TNF mediated hepatocyte apoptosis via BCL2 in acute liver failure. target gene hsa-mir-16-2 Liver Failure 22374434 miR-15b and miR-16 regulate TNF mediated hepatocyte apoptosis via BCL2 in acute liver failure. target gene hsa-mir-205 Nasopharyngeal Neoplasms 22374676 MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN. target gene hsa-mir-199b "Leukemia, Myeloid, Acute" 22374871 miR-199b-5p directly targets PODXL and DDR1 and decreased levels of miR-199b-5p correlate with elevated expressions of PODXL and DDR1 in acute myeloid leukemia. target gene hsa-mir-133a Head And Neck Neoplasms 22378351 The genome-wide gene expression analysis and bioinformatics study showed that actin-related protein 2/3 complex subunit 5 (ARPC5) is a candidate target of miR-133a. target gene hsa-mir-1 Bladder Neoplasms 22378464 Novel molecular targets regulated by tumor suppressors microRNA-1 and microRNA-133a in bladder cancer. target gene hsa-mir-133a Bladder Neoplasms 22378464 Novel molecular targets regulated by tumor suppressors microRNA-1 and microRNA-133a in bladder cancer. target gene hsa-mir-335 Neuroblastoma 22382496 MiRNA-335 Suppresses Neuroblastoma Cell Invasiveness By Direct Targeting of Multiple Genes from the non-Canonical TGF-§Ø©ãSignalling Pathway. target gene hsa-mir-506 Liver Cirrhosis 22383162 Upregulation of mir-506 leads to decreased AE2 expression in biliary epithelium of patients with primary biliary cirrhosis target gene hsa-mir-17 Hemangiosarcoma 22383169 The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. target gene hsa-mir-18a Hemangiosarcoma 22383169 The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. target gene hsa-mir-19a Hemangiosarcoma 22383169 The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. target gene hsa-mir-19b-1 Hemangiosarcoma 22383169 The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. target gene hsa-mir-20a Hemangiosarcoma 22383169 The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. target gene hsa-mir-92a-1 Hemangiosarcoma 22383169 The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. target gene hsa-let-7d Pancreatic Neoplasms 22384141 The miRNA is downregulated and regulate known PDAC oncogenes target gene hsa-mir-126 Pancreatic Neoplasms 22384141 The miRNA is downregulated and regulate known PDAC oncogenes target gene hsa-mir-16-1 Pancreatic Neoplasms 22384141 The miRNA is downregulated and regulate known PDAC oncogenes target gene hsa-mir-16-2 Pancreatic Neoplasms 22384141 The miRNA is downregulated and regulate known PDAC oncogenes target gene hsa-mir-409 Gastric Neoplasms 22388101 MicroRNA-409-3p regulates cell proliferation and apoptosis by targeting PHF10 in gastric cancer. target gene hsa-mir-216a "Carcinoma, Hepatocellular" 22392644 The androgen pathway stimulates microRNA-216a transcription to suppress the TSLC1 tumor suppressor gene in early hepatocarcinogenesis. target gene hsa-mir-328 Hypertension 22392900 The MicroRNA-328 Regulates Hypoxic Pulmonary Hypertension by Targeting at Insulin Growth Factor 1 Receptor and L-Type Calcium Channel-alpha1C. target gene hsa-mir-30a "Leukemia, Myeloid, Chronic-Phase" 22395361 Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells. target gene hsa-mir-221 "Carcinoma, Hepatocellular" 22396537 SND1-induced activation of NF-kappaB resulted in induction of miR-221 and subsequent induction of angiogenic factors Angiogenin and CXCL16. Inhibition of either of these components resulted in significant inhibition of SND1-induced angiogenesis thus highlighting the importance of this molecular cascade in regulating SND1 function. target gene hsa-mir-214 Urinary Bladder Cancer 22399294 MicroRNA-214 Suppresses The Growth and Invasiveness of Cervical Cancer Cells by Targeting UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7. target gene hsa-mir-25 Thyroid Neoplasms 22399519 Down-Regulation of the miR-25 and miR-30d Contributes to the Development of Anaplastic Thyroid Carcinoma Targeting the Polycomb Protein EZH2. target gene hsa-mir-30d Thyroid Neoplasms 22399519 Down-Regulation of the miR-25 and miR-30d Contributes to the Development of Anaplastic Thyroid Carcinoma Targeting the Polycomb Protein EZH2. target gene hsa-mir-182 Medulloblastoma 22402744 "Pleiotropic effects of miR-183~96~182 converge to regulate cell survival, proliferation and migration in medulloblastoma." target gene hsa-mir-183 Medulloblastoma 22402744 "Pleiotropic effects of miR-183~96~182 converge to regulate cell survival, proliferation and migration in medulloblastoma." target gene hsa-mir-96 Medulloblastoma 22402744 "Pleiotropic effects of miR-183~96~182 converge to regulate cell survival, proliferation and migration in medulloblastoma." target gene hsa-mir-133a-1 Prostate Neoplasms 22407299 "microRNA-133 inhibits cell proliferation, migration and invasion in prostate cancer cells by targeting the epidermal growth factor receptor." target gene hsa-mir-133a-2 Prostate Neoplasms 22407299 "microRNA-133 inhibits cell proliferation, migration and invasion in prostate cancer cells by targeting the epidermal growth factor receptor." target gene hsa-mir-133b Prostate Neoplasms 22407299 "microRNA-133 inhibits cell proliferation, migration and invasion in prostate cancer cells by targeting the epidermal growth factor receptor." target gene hsa-mir-200c Colorectal Carcinoma 22407310 miR-200c inhibits invasion and migration in human colon cancer cells SW480/620 by targeting ZEB1.miR-200c inhibits metastatic ability by targeting ZEB1 in colon cancer cells SW480/620 and suggested that modulation of miR-200c could serve as therapeutic to target gene hsa-mir-10a Pancreatic Neoplasms 22407312 "Based on the microarray data, the authors found frequent and marked overexpression of miR-10a, miR-92, and miR-17-5p in pancreatic cancer cell lines. MicroRNA-10a is Overexpressed in Human Pancreatic Cancer and Involved in Its Invasiveness Partially via Suppression of the HOXA1 Gene." target gene hsa-mir-17 Pancreatic Neoplasms 22407312 "Based on the microarray data, the authors found frequent and marked overexpression of miR-10a, miR-92, and miR-17-5p in pancreatic cancer cell lines. MicroRNA-10a is Overexpressed in Human Pancreatic Cancer and Involved in Its Invasiveness Partially via Suppression of the HOXA1 Gene." target gene hsa-mir-92a-1 Pancreatic Neoplasms 22407312 "Based on the microarray data, the authors found frequent and marked overexpression of miR-10a, miR-92, and miR-17-5p in pancreatic cancer cell lines. MicroRNA-10a is Overexpressed in Human Pancreatic Cancer and Involved in Its Invasiveness Partially via Suppression of the HOXA1 Gene." target gene hsa-mir-27a Breast Neoplasms 22407812 "Betulinic acid decreases ER-negative breast cancer cell growth in vitro and in vivo: Role of Sp transcription factors and microRNA-27a:ZBTB10.BA induced cell cycle arrest in the G2/M phase and increased Myt-1 mRNA (a microRNA-27a target gene), which causes inhibition in G2/M by phosphorylation of cdc2." target gene hsa-let-7f-1 Breast Neoplasms 22407818 "Aromatase inhibitor treatment of breast cancer cells increases the expression of let-7f, a microRNA targeting CYP19A1." target gene hsa-mir-148a Myositis Ossificans 22408438 "ACVR1, a Therapeutic Target of Fibrodysplasia Ossificans Progressiva, Is Negatively Regulated by miR-148a." target gene hsa-mir-520h Lung Neoplasms 22410781 MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol. target gene hsa-mir-365a Polycystic Kidney Disease 22411058 PKHD1 post-transcriptionally modulated by miR-365-1 inhibits cell-cell adhesion. target gene hsa-mir-125b-1 Glioblastoma 22415301 Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma. target gene hsa-mir-125b-2 Glioblastoma 22415301 Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma. target gene hsa-mir-34b Melanoma 22419847 MicroRNA-34b/c suppresses uveal melanoma cell proliferation and migration through multiple targets. target gene hsa-mir-34c Melanoma 22419847 MicroRNA-34b/c suppresses uveal melanoma cell proliferation and migration through multiple targets. target gene hsa-mir-542 Lung Neoplasms 22426479 miR-542-5p targets EGFR and inhibited the growth of human lung cancer cells. target gene hsa-mir-25 Glioblastoma 22431589 "In this study, two miRNAs, miR-25 and -32, are identified as p53-repressed miRNAs by p53-dependent negative regulation of their transcriptional regulators, E2F1 and MYC. However, miR-25 and -32 result in p53 accumulation by directly targeting Mdm2 and TSC1, which are negative regulators of p53." target gene hsa-mir-32 Glioblastoma 22431589 "In this study, two miRNAs, miR-25 and -32, are identified as p53-repressed miRNAs by p53-dependent negative regulation of their transcriptional regulators, E2F1 and MYC. However, miR-25 and -32 result in p53 accumulation by directly targeting Mdm2 and TSC1, which are negative regulators of p53." target gene hsa-mir-141 Kidney Neoplasms 22431721 "miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms." target gene hsa-mir-192 Kidney Neoplasms 22431721 "miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms." target gene hsa-mir-200c Kidney Neoplasms 22431721 "miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms." target gene hsa-mir-215 Kidney Neoplasms 22431721 "miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms." target gene hsa-let-7c "Carcinoma, Hepatocellular" 22433309 let-7c can inhibit proliferation of HCCLM3 cells and increase the proportion of cells in G1 phase. The mechanism may be that let-7c represses the expressions of cyclin D1 at both protein and mRNA levels. target gene hsa-mir-21 Breast Neoplasms 22435731 MiR-21 regulates EMT phenotype and HIF-1§Ø©ãexpression in third-sphereforming breast cancer stem cell-like cells. target gene hsa-mir-17 Preeclampsia 22438230 "Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta." target gene hsa-mir-20a Preeclampsia 22438230 "Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta." target gene hsa-mir-20b Preeclampsia 22438230 "Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta." target gene hsa-mir-135a-1 Breast Neoplasms 22439757 miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10. target gene hsa-mir-135a-2 Breast Neoplasms 22439757 miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10. target gene hsa-mir-128-1 Glioma 22442669 miR-128 expression levels were decreased in glioma. MiR-128 Inhibits Tumor Growth and Angiogenesis by Targeting p70S6K1. target gene hsa-mir-128-2 Glioma 22442669 miR-128 expression levels were decreased in glioma. MiR-128 Inhibits Tumor Growth and Angiogenesis by Targeting p70S6K1. target gene hsa-mir-181b-1 Liver Cirrhosis 22446332 miR-181b Promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients. target gene hsa-mir-181b-2 Liver Cirrhosis 22446332 miR-181b Promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients. target gene hsa-mir-328 Myopia 22447870 MicroRNA-328 may influence myopia development by mediating the PAX6 gene. target gene hsa-mir-219 "Carcinoma, Hepatocellular" 22449976 MiR-219-5p inhibits hepatocellular carcinoma cell proliferation by targeting glypican-3. target gene hsa-mir-20a Urinary Bladder Cancer 22449978 miR-20a promotes migration and invasion by regulating TNKS2 in human cervical cancer cells. target gene hsa-mir-124-1 Gastric Neoplasms 22450659 MiR-124 Inhibits Cell Proliferation in Gastric Cancer through Downregulation of SPHK1. target gene hsa-mir-124-2 Gastric Neoplasms 22450659 MiR-124 Inhibits Cell Proliferation in Gastric Cancer through Downregulation of SPHK1. target gene hsa-mir-124-3 Gastric Neoplasms 22450659 MiR-124 Inhibits Cell Proliferation in Gastric Cancer through Downregulation of SPHK1. target gene hsa-mir-372 Lung Neoplasms 22451061 "In addition, there is evidence that miR-372 posttranscriptionally downregulates large tumor suppressor, homolog 2 (Lats2), resulting in tumorigenesis and proliferation. " target gene hsa-mir-133a-1 Ovarian Neoplasms 22452920 "Other pairs of potentially biological relevance include: hsa-miR-145/E2F3, hsa-miR-139-5p/TOP2A, and hsa-miR-133a/GCLC." target gene hsa-mir-133a-2 Ovarian Neoplasms 22452920 "Other pairs of potentially biological relevance include: hsa-miR-145/E2F3, hsa-miR-139-5p/TOP2A, and hsa-miR-133a/GCLC." target gene hsa-mir-145 Ovarian Neoplasms 22452920 "Other pairs of potentially biological relevance include: hsa-miR-145/E2F3, hsa-miR-139-5p/TOP2A, and hsa-miR-133a/GCLC." target gene hsa-mir-328 Colorectal Carcinoma 22453125 MicroRNA expression profiling identifies miR-328 regulates cancer stem cell-like SP cells in colorectal cancer. target gene hsa-mir-23a Colorectal Carcinoma 22455847 "MiR-23a expression promotes colon carcinoma cell growth, invasion and metastasis through inhibition of MTSS gene." target gene hsa-mir-143 Esophageal Neoplasms 22457808 The Cluster of miR-143 and miR-145 Affects the Risk for Esophageal Squamous Cell Carcinoma through Co-Regulating Fascin Homolog 1. target gene hsa-mir-145 Esophageal Neoplasms 22457808 The Cluster of miR-143 and miR-145 Affects the Risk for Esophageal Squamous Cell Carcinoma through Co-Regulating Fascin Homolog 1. target gene hsa-mir-320a Colorectal Carcinoma 22459450 MicroRNA-320a suppresses human colon cancer cell proliferation by directly targeting beta-catenin. target gene hsa-mir-125b-1 Endometrial Neoplasms 22460089 MicroRNA-125b down-regulation mediates endometrial cancer invasion by targeting ERBB2. target gene hsa-mir-125b-2 Endometrial Neoplasms 22460089 MicroRNA-125b down-regulation mediates endometrial cancer invasion by targeting ERBB2. target gene hsa-mir-21 Gastric Neoplasms 22464652 "MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer." target gene hsa-mir-483 Glioma 22465663 MiR-483-5p suppresses the proliferation of glioma cells via directly targeting ERK1. target gene hsa-mir-93 Ovarian Neoplasms 22465665 "Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells." target gene hsa-mir-26a-1 Lung Neoplasms 22469510 MicroRNA-26a regulates tumorigenic properties of EZH2 in human lung carcinoma cells. target gene hsa-mir-26a-2 Lung Neoplasms 22469510 MicroRNA-26a regulates tumorigenic properties of EZH2 in human lung carcinoma cells. target gene hsa-mir-125b-1 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 22469780 B-cell regulator of immunoglobulin heavy chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells. target gene hsa-mir-125b-2 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 22469780 B-cell regulator of immunoglobulin heavy chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells. target gene hsa-mir-495 Gastric Neoplasms 22469786 MiR-495 and miR-551a inhibit the migration and invasion of human gastric cancer cells by directly interacting with PRL-3. target gene hsa-mir-551a Gastric Neoplasms 22469786 MiR-495 and miR-551a inhibit the migration and invasion of human gastric cancer cells by directly interacting with PRL-3. target gene hsa-mir-183 Ovarian Neoplasms 22469921 "Tiam1, negatively regulated by miR-22, miR-183 and miR-31, is involved in migration, invasion and viability of ovarian cancer cells." target gene hsa-mir-22 Ovarian Neoplasms 22469921 "Tiam1, negatively regulated by miR-22, miR-183 and miR-31, is involved in migration, invasion and viability of ovarian cancer cells." target gene hsa-mir-31 Ovarian Neoplasms 22469921 "Tiam1, negatively regulated by miR-22, miR-183 and miR-31, is involved in migration, invasion and viability of ovarian cancer cells." target gene hsa-mir-143 Head And Neck Neoplasms 22469988 miR-143 regulates hexokinase 2 expression in cancer cells. target gene hsa-mir-155 Glioblastoma 22470130 miR-155 is up-regulated in primary and secondary glioblastoma and promotes tumour growth by inhibiting GABA receptors. target gene hsa-mir-140 "Squamous Cell Carcinoma, Oral" 22470160 "miR-140-3p, miR-29c, and miR-29a were differentially expressed in metastasis versus nonmetastatic samples and had a strong positive correlation with their DNA copy numbers and a negative correlation with the expression of their target genes." target gene hsa-mir-29a "Squamous Cell Carcinoma, Oral" 22470160 "miR-140-3p, miR-29c, and miR-29a were differentially expressed in metastasis versus nonmetastatic samples and had a strong positive correlation with their DNA copy numbers and a negative correlation with the expression of their target genes." target gene hsa-mir-29c "Squamous Cell Carcinoma, Oral" 22470160 "miR-140-3p, miR-29c, and miR-29a were differentially expressed in metastasis versus nonmetastatic samples and had a strong positive correlation with their DNA copy numbers and a negative correlation with the expression of their target genes." target gene hsa-mir-223 Gastric Neoplasms 22470493 Stathmin1 Plays Oncogenic Role and Is a Target of MicroRNA-223 in Gastric Cancer. target gene hsa-mir-145 Osteosarcoma 22472569 MicroRNA-145 targets vascular endothelial growth factor and inhibits invasion and metastasis of osteosarcoma cells. target gene hsa-mir-135b Prostate Neoplasms 22473899 The results show that MUC1-C activates a posttranscriptional mechanism involving miR-135b-mediated downregulation of AR mRNA levels. target gene hsa-mir-30a Breast Neoplasms 22476851 MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer. target gene hsa-mir-34a Colon Neoplasms 22479251 "miR-34a induces colon cancer apoptosis through SIRT1, and miR-34a also promotes senescence in endothelial cells via SIRT1." target gene hsa-mir-34a Glioma 22479456 miR-34a Repression in Proneural Malignant Gliomas Upregulates Expression of Its Target PDGFRA and Promotes Tumorigenesis. target gene hsa-mir-141 Hepatitis B Virus Infection 22479552 MicroRNA-141 Represses HBV Replication by Targeting PPARA target gene hsa-mir-107 Myocardial Infarction 22482882 IPC enhances stem cell survival via the combined participation of hypoxia responsive miRs miR-107 and miR-210 via their respective putative target genes Pdcd10 and Casp8ap2. target gene hsa-mir-210 Myocardial Infarction 22482882 IPC enhances stem cell survival via the combined participation of hypoxia responsive miRs miR-107 and miR-210 via their respective putative target genes Pdcd10 and Casp8ap2. target gene hsa-mir-26a-1 Cholangiocarcinoma 22484120 MicroRNA-26a Promotes Cholangiocarcinoma Growth by Activating beta-catenin. target gene hsa-mir-26a-2 Cholangiocarcinoma 22484120 MicroRNA-26a Promotes Cholangiocarcinoma Growth by Activating beta-catenin. target gene hsa-mir-22 Lung Neoplasms 22484852 miR-22 suppresses lung cancer cell progression through post-transcriptional regulation of ErbB3. target gene hsa-mir-302c Skin Neoplasms 22486352 "Co-treatment with decitabine and doxorubicin results first in increased OCT4 and mir-145, then a decrease in both, suggesting that OCT4 and mir-145 regulate each other." target gene hsa-mir-1258 "Carcinoma, Lung, Non-Small-Cell" 22488243 The miR-1258 regulates the expression level of HPSE to influence the morbidity and metastasis of NSCLC. target gene hsa-mir-574 Colorectal Carcinoma 22490519 miR-574-5p negatively regulates Qki6/7 to impact §Ø©ãcatenin/Wnt signalling and the development of colorectal cancer. target gene hsa-mir-199a-1 Ovarian Neoplasms 22498306 MicroRNA-199a targets CD44 to suppress the tumorigenicity and multi-drug resistance of ovarian cancer-initiating cells. target gene hsa-mir-199a-2 Ovarian Neoplasms 22498306 MicroRNA-199a targets CD44 to suppress the tumorigenicity and multi-drug resistance of ovarian cancer-initiating cells. target gene hsa-mir-375 "Carcinoma, Hepatocellular" 22504094 miR-375 was down-regulated in HCC cells and tissues; it inhibited autophagy under hypoxic conditions by suppressing the conversion of LC3I to LC3II and thereby autophagic flux. target gene hsa-mir-145 Barrett Esophagus 22504665 microRNA-145 in Barrett's oesophagus: regulating BMP4 signalling via GATA6. target gene hsa-mir-27a Prostate Neoplasms 22505583 "Androgen regulated processing of the oncomir MiR-27a, which targets Prohibitin in prostate cancer." target gene hsa-mir-101 Prostate Neoplasms 22505648 The repressing activity of EZH2 on RKIP expression was dependent on histone deacetylase promoter recruitment and was negatively regulated upstream by miR-101. target gene hsa-mir-126 "Carcinoma, Lung, Non-Small-Cell" 22510476 miR-126 enhances the sensitivity of non-small cell lung cancer cells to anticancer agents by targeting vascular endothelial growth factor A. target gene hsa-mir-204 "Carcinoma, Renal Cell" 22516261 VHL-Regulated MiR-204 Suppresses Tumor Growth through Inhibition of LC3B-Mediated Autophagy in Renal Clear Cell Carcinoma. target gene hsa-mir-301a Demyelinating Diseases 22517757 "Both in vivo and in vitro, myelin antigen stimulation resulted in significant up-regulation of miR-301a, miR-21, and miR-155. miR-301a has a role in regulating the function of myelin-reactive T-helper type 17 cells, supporting a role for miR-301a as candidate for therapeutic targets for controlling of autoimmune demyelination." target gene hsa-mir-298 Breast Neoplasms 22521303 Increased expression of P-glycoprotein and doxorubicin chemoresistance of metastatic breast cancer is regulated by miR-298. target gene hsa-mir-126 Diabetes Mellitus 22525256 "Downregulation of microRNA-126 in endothelial progenitor cells from diabetes patients, impairs their functional properties, via target gene Spred-1." target gene hsa-mir-183 Osteosarcoma 22525461 Down-regulation of miR-183 promotes migration and invasion of osteosarcoma by targeting Ezrin. target gene hsa-mir-10b "Carcinoma, Hepatocellular" 22528944 MicroRNA-10b promotes migration and invasion through CADM1 in human hepatocellular carcinoma cells. target gene hsa-mir-3151 "Leukemia, Myeloid, Acute" 22529287 miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia. target gene hsa-mir-143 Colorectal Carcinoma 22533346 MicroRNA-143 targets MACC1 to inhibit cell invasion and migration in colorectal cancer. target gene hsa-mir-181b-1 Gastric Neoplasms 22539488 MicroRNA-181b targets cAMP responsive element binding protein 1 in gastric adenocarcinomas. target gene hsa-mir-181b-2 Gastric Neoplasms 22539488 MicroRNA-181b targets cAMP responsive element binding protein 1 in gastric adenocarcinomas. target gene hsa-mir-214 Cholangiocarcinoma 22540680 Downregulated miR-214 contributes to intrahepatic cholangiocarcinoma metastasis by targeting Twist. target gene hsa-mir-143 Colorectal Carcinoma 22549179 Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer. target gene hsa-mir-27a Breast Neoplasms 22553354 Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer. target gene hsa-mir-205 Prostate Neoplasms 22555458 miR-205 regulates basement membrane deposition in human prostate. target gene hsa-mir-106b Leiomyoma 22556343 "miR-93/106b and Their Host Gene, MCM7, Are Differentially Expressed in Leiomyomas and Functionally Target F3 and IL-8." target gene hsa-mir-93 Leiomyoma 22556343 "miR-93/106b and Their Host Gene, MCM7, Are Differentially Expressed in Leiomyomas and Functionally Target F3 and IL-8." target gene hsa-mir-10a Glioblastoma 22558405 "a tumor suppressor, CSMD1, as a downstream target of miR-10a and miR-10b, two of the up-regulated miRNAs." target gene hsa-mir-10b Glioblastoma 22558405 "a tumor suppressor, CSMD1, as a downstream target of miR-10a and miR-10b, two of the up-regulated miRNAs." target gene hsa-mir-19a Urinary Bladder Cancer 22561557 MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5. target gene hsa-mir-19b-1 Urinary Bladder Cancer 22561557 MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5. target gene hsa-mir-19b-2 Urinary Bladder Cancer 22561557 MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5. target gene hsa-mir-9-1 Neuroblastoma 22564723 "microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells." target gene hsa-mir-9-2 Neuroblastoma 22564723 "microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells." target gene hsa-mir-9-3 Neuroblastoma 22564723 "microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells." target gene hsa-mir-181d Glioblastoma 22570426 miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression. target gene hsa-mir-10b Breast Neoplasms 22573479 Targeting of syndecan-1 by microRNA miR-10b promotes breast cancer cell motility and invasiveness via a Rho-GTPase- and E-cadherin-dependent mechanism. target gene hsa-mir-139 Colorectal Carcinoma 22580051 MiR-139 inhibits invasion and metastasis of colorectal cancer by targeting the type I insulin-like growth factor receptor. target gene hsa-mir-34a Glioblastoma 22580610 miR-34a functions as a tumor suppressor modulating EGFR in glioblastoma multiforme. target gene hsa-mir-181a-2 Gastric Neoplasms 22581522 MicroRNA-181a promotes gastric cancer by negatively regulating tumor suppressor KLF6. target gene hsa-mir-93 Colorectal Carcinoma 22581829 MicroRNA-93 inhibits tumor growth and early relapse of human colorectal cancer by affecting genes involved in the cell cycle. target gene hsa-mir-381 Lung Neoplasms 22592211 MicroRNA-381 represses ID1 and is deregulated in lung adenocarcinoma. target gene hsa-mir-145 Breast Neoplasms 22592534 MiR-145 inhibits tumor angiogenesis and growth by N-RAS and VEGF. target gene hsa-mir-103a-1 Colorectal Carcinoma 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. target gene hsa-mir-103a-2 Colorectal Carcinoma 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. target gene hsa-mir-103b-1 Colorectal Carcinoma 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. target gene hsa-mir-103b-2 Colorectal Carcinoma 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. target gene hsa-mir-107 Colorectal Carcinoma 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. target gene hsa-mir-150 Adenovirus Infection 22595456 Our study demonstrates that miR-150 regulates surfactant secretion through P2X7R. target gene hsa-mir-181a-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 22610076 miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes. target gene hsa-mir-181b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 22610076 miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes. target gene hsa-mir-181b-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 22610076 miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes. target gene hsa-mir-7-1 Gastric Neoplasms 22614005 MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor. target gene hsa-mir-7-2 Gastric Neoplasms 22614005 MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor. target gene hsa-mir-7-3 Gastric Neoplasms 22614005 MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor. target gene hsa-mir-27a Glioma 22614734 Lentiviral expression of anti-microRNAs targeting miR-27a inhibits proliferation and invasiveness of U87 glioma cells. target gene hsa-mir-27b Cryptosporidium infection 22615562 miR-27b targets KSRP to coordinate TLR4-mediated epithelial defense against Cryptosporidium parvum infection. target gene hsa-mir-181b Inflammation 22622040 MicroRNA-181b regulates NF-¦ÊB-mediated vascular inflammation. target gene hsa-mir-21 Glioma 22630347 MicroRNA-21 expression is regulated by §Ø©ãcatenin/STAT3 pathway and promotes glioma cell invasion by direct targeting RECK. target gene hsa-mir-10a Urinary Bladder Cancer 22634495 "MicroRNA-10a targets CHL1 and promotes cell growth, migration and invasion in human cervical cancer cells." target gene hsa-mir-200a Pancreatic Neoplasms 22637745 Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer. target gene hsa-mir-200b Pancreatic Neoplasms 22637745 Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer. target gene hsa-mir-200c Pancreatic Neoplasms 22637745 Re-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer. target gene hsa-mir-133a-1 Esophageal Neoplasms 22641236 CD47 expression regulated by the miR-133a tumor suppressor is a novel prognostic marker in esophageal squamous cell carcinoma. target gene hsa-mir-133a-2 Esophageal Neoplasms 22641236 CD47 expression regulated by the miR-133a tumor suppressor is a novel prognostic marker in esophageal squamous cell carcinoma. target gene hsa-mir-139 Colorectal Carcinoma 22642900 Regulation of RAP1B by miR-139 suppresses human colorectal carcinoma cell proliferation. target gene hsa-mir-21 Prostate Neoplasms 22642976 "miR-21 may acts as an oncomir by targeting RECK, a matrix metalloproteinase regulator, in prostate cancer." target gene hsa-mir-23b Inflammation 22660635 "The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-a." target gene hsa-mir-26a Heart Failure 22664106 Up-regulation of miR-26a promotes apoptosis of hypoxic rat neonatal cardiomyocytes by repressing GSK-3¦Â protein expression. target gene hsa-mir-1-1 "Carcinoma, Hepatocellular" 22664953 MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells. target gene hsa-mir-1-2 "Carcinoma, Hepatocellular" 22664953 MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells. target gene hsa-mir-499a "Carcinoma, Hepatocellular" 22664953 MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells. target gene hsa-mir-499b "Carcinoma, Hepatocellular" 22664953 MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells. target gene hsa-mir-193b Colorectal Carcinoma 22674437 "MicroRNA-199a-3p, microRNA-193b, and microRNA-320c are correlated to aging and regulate human cartilage metabolism." target gene hsa-mir-199a-1 Colorectal Carcinoma 22674437 "MicroRNA-199a-3p, microRNA-193b, and microRNA-320c are correlated to aging and regulate human cartilage metabolism." target gene hsa-mir-199a-2 Colorectal Carcinoma 22674437 "MicroRNA-199a-3p, microRNA-193b, and microRNA-320c are correlated to aging and regulate human cartilage metabolism." target gene hsa-mir-320c-1 Colorectal Carcinoma 22674437 "MicroRNA-199a-3p, microRNA-193b, and microRNA-320c are correlated to aging and regulate human cartilage metabolism." target gene hsa-mir-320c-2 Colorectal Carcinoma 22674437 "MicroRNA-199a-3p, microRNA-193b, and microRNA-320c are correlated to aging and regulate human cartilage metabolism." target gene hsa-mir-297 Colorectal Carcinoma 22676135 miR-297 modulates multidrug resistance in human colorectal carcinoma by down-regulating MRP-2. target gene hsa-mir-222 Colorectal Carcinoma 22677042 MiR-222 modulates multidrug resistance in human colorectal carcinoma by down-regulating ADAM-17. target gene hsa-mir-625 Gastric Neoplasms 22677169 Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer by targeting ILK. target gene hsa-mir-101 "Leukemia, Lymphoblastic, Acute" 22677230 We also found that p23 was regulated by hsa-miR-101 which was down-regulated in childhood ALL cases. target gene hsa-mir-21 Breast Neoplasms 22678116 miR-21 is targeted by omega-3 polyunsaturated fatty acid to regulate breast tumor CSF-1 expression. target gene hsa-mir-203 Inflammation 22679274 The top-ranked predicted target of the highly down-regulated miRNA-203 in asthmatic cells was the aquaporin gene AQP4. target gene hsa-mir-34a Glioma 22684560 MicroRNA-34a inhibits human brain glioma cell growth by down-regulation of Notch1. target gene hsa-mir-34a Urinary Bladder Cancer 22684561 microRNA-34a inhibit cell migration and invasion of invasive urothelial bladder carcinoma by targeting Notch1. target gene hsa-mir-15a Odontogenic Tumors 22684875 miR-15a/16-1 influences BCL2 expression in keratocystic odontogenic tumors. target gene hsa-mir-16-1 Odontogenic Tumors 22684875 miR-15a/16-1 influences BCL2 expression in keratocystic odontogenic tumors. target gene hsa-mir-16-2 Odontogenic Tumors 22684875 miR-15a/16-1 influences BCL2 expression in keratocystic odontogenic tumors. target gene hsa-mir-590 "Carcinoma, Hepatocellular" 22684895 MicroRNA-590-5p regulates proliferation and invasion in human hepatocellular carcinoma cells by targeting TGF-beta RII. target gene hsa-mir-200a Leiomyoma 22685266 "miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5." target gene hsa-mir-200c Leiomyoma 22685266 "miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5." target gene hsa-mir-93 Breast Neoplasms 22685420 MicroRNA93 regulates proliferation and differentiation of normal and malignant breast stem cells. target gene hsa-mir-21 "Carcinoma, Renal Cell" 22685542 microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion. target gene hsa-mir-143 Colon Neoplasms 22691140 microRNA-143 down-regulates Hexokinase 2 in colon cancer cells. target gene hsa-mir-125b-1 Breast Neoplasms 22693547 MicroRNA-125b induces metastasis by targeting STARD13 in MCF-7 and MDA-MB-231 breast cancer cells. target gene hsa-mir-125b-2 Breast Neoplasms 22693547 MicroRNA-125b induces metastasis by targeting STARD13 in MCF-7 and MDA-MB-231 breast cancer cells. target gene hsa-mir-30c-1 Breast Neoplasms 22701724 miR-30c overexpression inhibited proliferation of breast cancer cells.miR-30c binds the 3'UTR of KRAS transcripts and expression of pre-miR-30c down-regulated KRAS mRNA and protein. target gene hsa-mir-30c-2 Breast Neoplasms 22701724 miR-30c overexpression inhibited proliferation of breast cancer cells.miR-30c binds the 3'UTR of KRAS transcripts and expression of pre-miR-30c down-regulated KRAS mRNA and protein. target gene hsa-mir-34a Neuroblastoma 22703967 Inhibition of cyclin-dependent kinase 1-induced cell death in neuroblastoma cells through the microRNA-34a-MYCN-survivin pathway. target gene hsa-mir-21 Glioblastoma 22709411 MiR-21 Modulates hTERT Through a STAT3-Dependent Manner on Glioblastoma Cell Growth. target gene hsa-mir-23b Prostate Neoplasms 22710126 MicroRNA-23b downregulates peroxiredoxin III in human prostate cancer. target gene hsa-mir-497 Colorectal Carcinoma 22710713 MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer. target gene hsa-mir-632 Breast Neoplasms 22710984 Micro-RNA-632 downregulates DNAJB6 in breast cancer. target gene hsa-mir-146a Gastric Neoplasms 22711166 microRNA-146a targets the L1 cell adhesion molecule and suppresses the metastatic potential of gastric cancer. target gene hsa-mir-203 Breast Neoplasms 22713668 MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells. target gene hsa-mir-204 Nervous System Diseases [unspecific] 22718995 MicroRNA-204 critically regulates carcinogenesis in malignant peripheral nerve sheath tumors. target gene hsa-mir-155 Gastrointestinal Neoplasms 22719182 "As a possible new mechanism underlying MSI, overexpression of miR-155 has been shown to downregulate expression of MLH1, MSH2, and MSH6. Thus, a subset of MSI-positive (MSI+) cancers without known MMR defects may result from miR-155 overexpression. " target gene hsa-mir-195 Alzheimer Disease 22721728 MicroRNA-195 downregulates Alzheimer's disease amyloid-beta production by targeting BACE1. target gene hsa-mir-708 Ewing Sarcoma 22723308 "EWS/FLI1 Regulates EYA3 in Ewing Sarcoma via Modulation of miRNA-708, Resulting in Increased Cell Survival and Chemoresistance." target gene hsa-mir-195 Preeclampsia 22723898 Downregulated miR-195 detected in preeclamptic placenta affects trophoblast cell invasion via modulating ActRIIA expression. target gene hsa-mir-137 Breast Neoplasms 22723937 MiR-137 targets estrogen-related receptor alpha and impairs the proliferative and migratory capacity of breast cancer cells. target gene hsa-mir-337 "Carcinoma, Lung, Non-Small-Cell" 22723956 miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers. target gene hsa-mir-17 Urinary Bladder Cancer 22730212 MiR-17-5p targets TP53INP1 and regulates cell proliferation and apoptosis of cervical cancer cells. target gene hsa-mir-153-1 Alzheimer Disease 22733824 MicroRNA-153 physiologically inhibits expression of amyloid-beta precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients. target gene hsa-mir-153-2 Alzheimer Disease 22733824 MicroRNA-153 physiologically inhibits expression of amyloid-beta precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients. target gene hsa-mir-155 Breast Neoplasms 22736789 This is the first review examining the role of miR-155 in breast cancer progression. The collated data of target genes and biologic pathways of miR-155 identified in this review suggest new avenues of research for this oncogenic miRNA. target gene hsa-mir-138-1 Nasopharyngeal Neoplasms 22739938 MiR-138 suppressed nasopharyngeal carcinoma growth and tumorigenesis by targeting the CCND1 oncogene. target gene hsa-mir-138-2 Nasopharyngeal Neoplasms 22739938 MiR-138 suppressed nasopharyngeal carcinoma growth and tumorigenesis by targeting the CCND1 oncogene. target gene hsa-mir-23b Glioblastoma 22745829 miRNA expression profiling in migrating glioblastoma cells: regulation of cell migration and invasion by miR-23b via targeting of Pyk2. target gene hsa-mir-513a-1 Lung Neoplasms 22749944 miR-513a-3p sensitizes human lung adenocarcinoma cells to chemotherapy by targeting GSTP1. target gene hsa-mir-513a-2 Lung Neoplasms 22749944 miR-513a-3p sensitizes human lung adenocarcinoma cells to chemotherapy by targeting GSTP1. target gene hsa-mir-410 Glioma 22750473 MiR-410 regulates MET to influence the proliferation and invasion of glioma. target gene hsa-mir-34a Glioblastoma 22750848 microRNA Regulatory Network Inference Identifies miR-34a as a Novel Regulator of TGF-beta Signaling in Glioblastoma. target gene hsa-mir-29a Breast Neoplasms 22751119 Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4. target gene hsa-mir-29b-1 Breast Neoplasms 22751119 Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4. target gene hsa-mir-29b-2 Breast Neoplasms 22751119 Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4. target gene hsa-mir-29c Breast Neoplasms 22751119 Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4. target gene hsa-mir-23a Lung Neoplasms 22752005 MiR-23a regulates TGF-beta-induced epithelial-mesenchymal transition by targeting E-cadherin in lung cancer cells. target gene hsa-mir-9-1 Breast Neoplasms 22761433 MicroRNA-9 Inhibition of Cell Proliferation and Identification of Novel miR-9 Targets by Transcriptome Profiling in Breast Cancer Cells. target gene hsa-mir-9-2 Breast Neoplasms 22761433 MicroRNA-9 Inhibition of Cell Proliferation and Identification of Novel miR-9 Targets by Transcriptome Profiling in Breast Cancer Cells. target gene hsa-mir-9-3 Breast Neoplasms 22761433 MicroRNA-9 Inhibition of Cell Proliferation and Identification of Novel miR-9 Targets by Transcriptome Profiling in Breast Cancer Cells. target gene hsa-mir-145 Colon Neoplasms 22766504 MiR-145 regulates PAK4 via the MAPK pathway and exhibits an antitumor effect in human colon cells. target gene hsa-mir-138-1 "Carcinoma, Renal Cell" 22766839 Tumor suppressive microRNA-138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma. target gene hsa-mir-138-2 "Carcinoma, Renal Cell" 22766839 Tumor suppressive microRNA-138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma. target gene hsa-mir-218-1 Glioblastoma 22766851 MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1. target gene hsa-mir-218-2 Glioblastoma 22766851 MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1. target gene hsa-mir-125a "Carcinoma, Hepatocellular" 22768249 Ectopic expression of MiR-125a inhibits the proliferation and metastasis of hepatocellular carcinoma by targeting MMP11 and VEGF. target gene hsa-mir-21 Cholangiocarcinoma 22770403 PTEN and PDCD4 are bona fide targets of microRNA-21 in human cholangiocarcinoma. target gene hsa-mir-29a Multiple Sclerosis 22772450 miR-29ab Deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias That Is Dysregulated in Multiple Sclerosis. target gene hsa-mir-29b-1 Multiple Sclerosis 22772450 miR-29ab Deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias That Is Dysregulated in Multiple Sclerosis. target gene hsa-mir-29b-2 Multiple Sclerosis 22772450 miR-29ab Deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias That Is Dysregulated in Multiple Sclerosis. target gene hsa-mir-125b-1 "Squamous Cell Carcinoma, Skin or Unspecific" 22782903 "MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration, and Invasion." target gene hsa-mir-125b-2 "Squamous Cell Carcinoma, Skin or Unspecific" 22782903 "MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration, and Invasion." target gene hsa-mir-103a-1 Endometrial Neoplasms 22783422 microRNA-103 regulates the growth and invasion of endometrial cancer cells through the downregulation of tissue inhibitor of metalloproteinase 3. target gene hsa-mir-103a-2 Endometrial Neoplasms 22783422 microRNA-103 regulates the growth and invasion of endometrial cancer cells through the downregulation of tissue inhibitor of metalloproteinase 3. target gene hsa-mir-103b-1 Endometrial Neoplasms 22783422 microRNA-103 regulates the growth and invasion of endometrial cancer cells through the downregulation of tissue inhibitor of metalloproteinase 3. target gene hsa-mir-103b-2 Endometrial Neoplasms 22783422 microRNA-103 regulates the growth and invasion of endometrial cancer cells through the downregulation of tissue inhibitor of metalloproteinase 3. target gene hsa-mir-20a Prostate Neoplasms 22785209 CX43 expression is suppressed by miR-20a in the progression of human prostate cancer. target gene hsa-mir-21 Gastric Neoplasms 22792096 miR-21 Is a Promising Novel Biomarker for Lymph Node Metastasis in Patients with Gastric Cancer. target gene hsa-mir-125b-1 Melanoma 22797068 MicroRNA miR-125b controls melanoma progression by direct regulation of c-Jun protein expression. target gene hsa-mir-125b-2 Melanoma 22797068 MicroRNA miR-125b controls melanoma progression by direct regulation of c-Jun protein expression. target gene hsa-mir-193b Prostate Neoplasms 22797075 CFTR suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer. target gene hsa-mir-200a Thyroid Neoplasms 22797360 The miR-200 family regulates the epithelial-mesenchymal transition induced by EGF/EGFR in anaplastic thyroid cancer cells. target gene hsa-mir-200b Thyroid Neoplasms 22797360 The miR-200 family regulates the epithelial-mesenchymal transition induced by EGF/EGFR in anaplastic thyroid cancer cells. target gene hsa-mir-200c Thyroid Neoplasms 22797360 The miR-200 family regulates the epithelial-mesenchymal transition induced by EGF/EGFR in anaplastic thyroid cancer cells. target gene hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 22797699 "In the present study, we show that an 8-mer locked nucleic acid anti-miR-155 oligonucleotide targeting the seed region of miR-155 inhibits WM and chronic lymphocytic leukemia cell proliferation in vitro." target gene hsa-mir-21 Lung Neoplasms 22806311 miR-21 induces cell cycle at S phase and modulates cell proliferation by down-regulating hMSH2 in lung cancer. target gene hsa-mir-224 Breast Neoplasms 22809510 MicroRNA-224 targets RKIP to control cell invasion and expression of metastasis genes in human breast cancer cells. target gene hsa-mir-107 Pituitary Neoplasms 22811466 MicroRNA miR-107 is overexpressed in pituitary adenomas and in vitro inhibits the expression of aryl hydrocarbon receptor-interacting protein (AIP). target gene hsa-mir-324 Kidney Diseases [unspecific] 22822076 MicroRNA-324-3p Promotes Renal Fibrosis and Is a Target of ACE Inhibition. target gene hsa-mir-124-1 "Squamous Cell Carcinoma, Skin or Unspecific" 22828925 Down-regulation of miR-124/-214 in cutaneous squamous cell carcinoma mediates abnormal cell proliferation via the induction of ERK. target gene hsa-mir-124-2 "Squamous Cell Carcinoma, Skin or Unspecific" 22828925 Down-regulation of miR-124/-214 in cutaneous squamous cell carcinoma mediates abnormal cell proliferation via the induction of ERK. target gene hsa-mir-214 "Squamous Cell Carcinoma, Skin or Unspecific" 22828925 Down-regulation of miR-124/-214 in cutaneous squamous cell carcinoma mediates abnormal cell proliferation via the induction of ERK. target gene hsa-mir-146a "Leukemia, Myeloid, Acute" 22829170 "miR-146a and AMD3100, acting through different mechanism, downmodulate CXCR4 protein levels, impair leukemic cell proliferation and then may be used in combination with anti-leukemia drugs, for development of new therapeutic strategies." target gene hsa-mir-194-1 Breast Neoplasms 22829924 Modulation of MicroRNA-194 and Cell Migration by HER2-Targeting Trastuzumab in Breast Cancer. target gene hsa-mir-194-2 Breast Neoplasms 22829924 Modulation of MicroRNA-194 and Cell Migration by HER2-Targeting Trastuzumab in Breast Cancer. target gene hsa-mir-21 Breast Neoplasms 22832383 Matrine Inhibits Breast Cancer Growth Via miR-21/PTEN/Akt Pathway in MCF-7 Cells. target gene hsa-mir-126 "Carcinoma, Oral" 22836510 Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer. target gene hsa-mir-130a "Carcinoma, Hepatocellular" 22846564 Upregulated miR-130a increases drug resistance by regulating RUNX3 and Wnt signaling in cisplatin-treated HCC cell. target gene hsa-mir-203 Inflammation 22846677 "miR-203 may regulate expression of the novel nociceptive mediator PLAA after incision. Furthermore, the regulation of miR-203 and PLAA levels is reliant upon intact substance P signaling." target gene hsa-mir-10b Breast Neoplasms 22847191 MicroRNA-10b targets E-cadherin and modulates breast cancer metastasis. target gene hsa-mir-181a-1 Urinary Bladder Cancer 22847611 MiR-181a confers resistance of cervical cancer to radiation therapy through targeting the pro-apoptotic PRKCD gene. target gene hsa-mir-181a-2 Urinary Bladder Cancer 22847611 MiR-181a confers resistance of cervical cancer to radiation therapy through targeting the pro-apoptotic PRKCD gene. target gene hsa-mir-182 Melanoma 22848417 "miR-182, a p53 dependent miRNA, suppressed the expression of MITF, BCL2, cyclin D2 and functioned as a potent tumor suppressor in uveal melanoma cells." target gene hsa-mir-31 "Carcinoma, Oral" 22854067 Passenger strand miRNA miR-31* regulates the phenotypes of oral cancer cells by targeting RhoA. target gene hsa-mir-222 Prostate Neoplasms 22854542 Tumor suppressive microRNAs (miR-222 and miR-31) regulate molecular pathways based on microRNA expression signature in prostate cancer. target gene hsa-mir-31 Prostate Neoplasms 22854542 Tumor suppressive microRNAs (miR-222 and miR-31) regulate molecular pathways based on microRNA expression signature in prostate cancer. target gene hsa-mir-15a Leukemia 22856663 "we review the main achievements made on targeting of prosurvival Bcl-2 proteins through the use of different approaches, i.e. anti-sense methodology, small molecules that mimic the action of BH3 domain and microRNAs (mainly miRNA-15a and miRNA-16-1)." target gene hsa-mir-29b-1 Breast Neoplasms 22864815 "Three mRNAs (C1QTNF6, SPARC, and COL4A2) that are down-regulated by microRNA-29b and promote invasion ability in the breast cancer cell line MCF-7." target gene hsa-mir-29b-2 Breast Neoplasms 22864815 "Three mRNAs (C1QTNF6, SPARC, and COL4A2) that are down-regulated by microRNA-29b and promote invasion ability in the breast cancer cell line MCF-7." target gene hsa-mir-1271 "Carcinoma, Hepatocellular" 22865282 "miR-96, miR-129-1-3p, miR-1271, miR-1291 and miR-1303 differentially control GPC3 expression in HCC cells." target gene hsa-mir-129-1 "Carcinoma, Hepatocellular" 22865282 "miR-96, miR-129-1-3p, miR-1271, miR-1291 and miR-1303 differentially control GPC3 expression in HCC cells." target gene hsa-mir-129-2 "Carcinoma, Hepatocellular" 22865282 "miR-96, miR-129-1-3p, miR-1271, miR-1291 and miR-1303 differentially control GPC3 expression in HCC cells." target gene hsa-mir-1303 "Carcinoma, Hepatocellular" 22865282 "miR-96, miR-129-1-3p, miR-1271, miR-1291 and miR-1303 differentially control GPC3 expression in HCC cells." target gene hsa-mir-96 "Carcinoma, Hepatocellular" 22865282 "miR-96, miR-129-1-3p, miR-1271, miR-1291 and miR-1303 differentially control GPC3 expression in HCC cells." target gene hsa-mir-214 Esophageal Neoplasms 22867052 microRNA-98 and microRNA-214 post-transcriptionally regulate enhancer of zeste homolog 2 and inhibit migration and invasion in human esophageal squamous cell carcinoma. target gene hsa-mir-98 Esophageal Neoplasms 22867052 microRNA-98 and microRNA-214 post-transcriptionally regulate enhancer of zeste homolog 2 and inhibit migration and invasion in human esophageal squamous cell carcinoma. target gene hsa-mir-145 Glioblastoma 22869051 "NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma." target gene hsa-mir-542 Glioma 22871495 The Putative Tumor Suppressor miR-524-5p Directly Targets Jagged-1 and Hes-1 in Glioma. target gene hsa-mir-205 Melanoma 22871739 E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry. target gene hsa-mir-7-1 Breast Neoplasms 22876288 MicroRNA-7 Inhibits Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer Cells via Targeting FAK Expression. target gene hsa-mir-7-2 Breast Neoplasms 22876288 MicroRNA-7 Inhibits Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer Cells via Targeting FAK Expression. target gene hsa-mir-7-3 Breast Neoplasms 22876288 MicroRNA-7 Inhibits Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer Cells via Targeting FAK Expression. target gene hsa-mir-196a-1 "Carcinoma, Lung, Non-Small-Cell" 22876840 MicroRNA-196a promotes non-small cell lung cancer cell proliferation and invasion through targeting HOXA5. target gene hsa-mir-196a-2 "Carcinoma, Lung, Non-Small-Cell" 22876840 MicroRNA-196a promotes non-small cell lung cancer cell proliferation and invasion through targeting HOXA5. target gene hsa-mir-1 Coronary Artery Disease 22883088 Association study on the microRNA-1 target gene polymorphism and the risk of premature coronary artery disease target gene hsa-mir-137 Schizophrenia 22883350 Candidate schizophrenia gene ZNF804A is a target for hsa-miR-137. target gene hsa-mir-133b "Carcinoma, Lung, Non-Small-Cell" 22883469 MicroRNA-133b Inhibits the Growth of Non-small Cell Lung Cancer by Targeting the Epidermal Growth Factor Receptor. target gene hsa-mir-26a-1 Lung Neoplasms 22885155 MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN. target gene hsa-mir-26a-2 Lung Neoplasms 22885155 MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN. target gene hsa-mir-203 "Carcinoma, Hepatocellular" 22886454 miR-203 inhibits proliferation of hepatocellular carcinoma cells by targeting survivin. target gene hsa-mir-335 Meningioma 22886530 miR-335 promotes cell proliferation by directly targeting Rb1 in meningiomas. target gene hsa-mir-195 "Carcinoma, Hepatocellular" 22888524 MiR-195 regulates cell apoptosis of human hepatocellular carcinoma cells by targeting LATS2. target gene hsa-mir-24 Heart Failure 22891046 MiR-24-mediated suppression of JP2 expression provides a novel molecular mechanism for E-C coupling regulation in heart cells and suggests a new target against heart failure. target gene hsa-mir-124-1 Colorectal Carcinoma 22895557 "miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect." target gene hsa-mir-124-2 Colorectal Carcinoma 22895557 "miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect." target gene hsa-mir-137 Colorectal Carcinoma 22895557 "miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect." target gene hsa-mir-340 Colorectal Carcinoma 22895557 "miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect." target gene hsa-mir-92a-1 Glioblastoma 22895567 miR-92a is a critical regulator of the apoptosis pathway in glioblastoma with inverse expression of BCL2L11. target gene hsa-mir-92a-2 Glioblastoma 22895567 miR-92a is a critical regulator of the apoptosis pathway in glioblastoma with inverse expression of BCL2L11. target gene hsa-mir-132 Dementia 22895706 "TMEM106B, the Risk Gene for Frontotemporal Dementia, Is Regulated by the microRNA-132/212 Cluster and Affects Progranulin Pathways." target gene hsa-mir-212 Dementia 22895706 "TMEM106B, the Risk Gene for Frontotemporal Dementia, Is Regulated by the microRNA-132/212 Cluster and Affects Progranulin Pathways." target gene hsa-mir-140 "Carcinoma, Hepatocellular" 22898998 MiRNA-140 acts as a liver tumor suppressor by controlling NF-kB activity via directly targeting Dnmt1 expression. target gene hsa-mir-370 "Leukemia, Myeloid, Acute" 22900969 The tumor suppressive role of miRNA-370 by targeting FoxM1 in acute myeloid leukemia. target gene hsa-mir-193a Endometrial Neoplasms 22907428 YY1 overexpression was found to be a consequence of miR-193a-5p downregulation through direct miR-193a-5p-YY1 interplay. target gene hsa-mir-331 Prostate Neoplasms 22908221 "Regulation of expression of deoxyhypusine hydroxylase (DOHH), the enzyme that catalyzes the activation of eIF5A, by miR-331-3p and miR-642-5p in prostate cancer cells." target gene hsa-mir-642a Prostate Neoplasms 22908221 "Regulation of expression of deoxyhypusine hydroxylase (DOHH), the enzyme that catalyzes the activation of eIF5A, by miR-331-3p and miR-642-5p in prostate cancer cells." target gene hsa-mir-642b Prostate Neoplasms 22908221 "Regulation of expression of deoxyhypusine hydroxylase (DOHH), the enzyme that catalyzes the activation of eIF5A, by miR-331-3p and miR-642-5p in prostate cancer cells." target gene hsa-mir-128-1 Ovarian Neoplasms 22909061 "Both miR-128 and miR-152 down-regulate CSF-1 mRNA and protein expression in ovarian cancer cells leading to decreased cell motility and adhesion in vitro, two major aspects of the metastatic potential of cancer cells." target gene hsa-mir-128-2 Ovarian Neoplasms 22909061 "Both miR-128 and miR-152 down-regulate CSF-1 mRNA and protein expression in ovarian cancer cells leading to decreased cell motility and adhesion in vitro, two major aspects of the metastatic potential of cancer cells." target gene hsa-mir-24-2 Breast Neoplasms 22911661 Preferential star strand biogenesis of pre-miR-24-2 targets PKC-alpha and suppresses cell survival in MCF-7 breast cancer cells. target gene hsa-mir-106a Colorectal Carcinoma 22912877 "MiR-106a inhibits the expression of transforming growth factor-beta receptor 2 (TGFBR2), leading to increased CRC cell migration and invasion. Importantly, miR-106a expression levels in primary CRCs are correlated with clinical cancer progression." target gene hsa-mir-122 Prostate Neoplasms 22914437 "miR122 regulation of Ad6 significantly improves its safety profile after systemic administration, which allows increasing therapeutic doses leading to improved anticancer efficacy of systemic treatment for castration-resistant prostate cancer." target gene hsa-mir-10b Neoplasms [unspecific] 22915757 "MiR-10b downregulates the stress-induced cell surface molecule MICB, a critical ligand for cancer cell recognition by natural killer cells." target gene hsa-let-7c Atherosclerosis 22917031 Our data suggest that let-7c contributes to endothelial apoptosis through suppression of Bcl-xl target gene hsa-mir-182 Peripheral Nerve Injury 22917588 "Our data indicate that nerve injury inhibits SC proliferation and migration through rapid regulation of miR-182 by targeting FGF9 and NTM, providing novel insights into the roles of miRNAs in nerve injury and repair." target gene hsa-mir-203 Psoriasis 22917968 Our findings suggest that miR-203 serves to fine-tune cytokine signaling and may dampen skin immune responses by repressing key pro-inflammatory cytokines. target gene hsa-mir-183 Osteosarcoma 22922800 miR-183 inhibits the metastasis of osteosarcoma via downregulation of the expression of Ezrin in F5M2 cells. target gene hsa-mir-15a Osteosarcoma 22922827 miR-15a and miR-16-1 downregulate CCND1 and induce apoptosis and cell cycle arrest in osteosarcoma. target gene hsa-mir-16-1 Osteosarcoma 22922827 miR-15a and miR-16-1 downregulate CCND1 and induce apoptosis and cell cycle arrest in osteosarcoma. target gene hsa-mir-100 Breast Neoplasms 22926517 miR-100 suppresses IGF2 and inhibits breast tumorigenesis by interfering with proliferation and survival signaling. target gene hsa-mir-214 Ovarian Neoplasms 22927443 MiR-214 regulates ovarian cancer cell stemness by targeting p53/nanog. target gene hsa-mir-214 "Carcinoma, Lung, Non-Small-Cell" 22929890 "miRNA-214 modulates radiotherapy response of non-small cell lung cancer cells through regulation of p38MAPK, apoptosis and senescence." target gene hsa-mir-29b-1 Nervous System Diseases [unspecific] 22932723 Exosome-mediated shuttling of microRNA-29b regulates HIV Tat and morphine-mediated Neuronal dysfunction. target gene hsa-mir-29b-2 Nervous System Diseases [unspecific] 22932723 Exosome-mediated shuttling of microRNA-29b regulates HIV Tat and morphine-mediated Neuronal dysfunction. target gene hsa-mir-544a Gastric Neoplasms 22934698 Oncogenic miR-544 is an Important Molecular Target in Gastric Cancer. target gene hsa-mir-544b Gastric Neoplasms 22934698 Oncogenic miR-544 is an Important Molecular Target in Gastric Cancer. target gene hsa-mir-148a Breast Neoplasms 22935141 "Overexpression of miR-148a or miR-152 significantly inhibits BC cell proliferation, colony formation and tumor angiogenesis via targeting IGF-IR and IRS1 and suppressing their downstream AKT and MAPK/ERK signaling pathways." target gene hsa-mir-152 Breast Neoplasms 22935141 "Overexpression of miR-148a or miR-152 significantly inhibits BC cell proliferation, colony formation and tumor angiogenesis via targeting IGF-IR and IRS1 and suppressing their downstream AKT and MAPK/ERK signaling pathways." target gene hsa-mir-124-1 "Carcinoma, Hepatocellular" 22940133 MiR-124 suppresses cell proliferation in hepatocellular carcinoma by targeting PIK3CA. target gene hsa-mir-124-2 "Carcinoma, Hepatocellular" 22940133 MiR-124 suppresses cell proliferation in hepatocellular carcinoma by targeting PIK3CA. target gene hsa-mir-203 Esophageal Neoplasms 22940702 miR-203 inhibits the migration and invasion of esophageal squamous cell carcinoma by regulating LASP1. target gene hsa-mir-338 Hepatitis B Virus Infection 22942717 miR-338-3p Is Down-Regulated by Hepatitis B Virus X and Inhibits Cell Proliferation by Targeting the 3'-UTR Region of CyclinD1. target gene hsa-mir-205 Prostate Neoplasms 22949650 Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. target gene hsa-mir-19a Breast Neoplasms 22952885 "These results suggest that the IMPDH1 and NPEPL1 genes are direct targets of miR-19a in breast cancer, while the exogenous expression of these genes is not associated with the growth suppression of MCF-7 cells." target gene hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 22956424 "MicroRNA-21 (miR-21) expression promotes growth, metastasis, and chemo- or radioresistance in non-small cell lung cancer cells by targeting PTEN." target gene hsa-mir-181a Atherosclerosis 22956783 "Thus, abundance of miR-181a reduced c-Fos protein, whereas inhibition of miR-181a increased c-Fos protein in BMDCs. We therefore suggest that miR-181a attenuates ox-LDL-stimulated immune inflammation responses by targeting c-Fos in DCs." target gene hsa-mir-122 Hepatitis C Virus Infection 22957141 Silencing of microRNA-122 enhances interferon-alpha signaling in the liver through regulating SOCS3 promoter methylation. target gene hsa-let-7a Lung Neoplasms 22970031 "The upregulation of let-7a/7g repressed the expression of their targets,C-MYC and the regulatory protein of LIN-28, at the mRNA and protein levels." target gene hsa-let-7g Lung Neoplasms 22970031 "The upregulation of let-7a/7g repressed the expression of their targets,C-MYC and the regulatory protein of LIN-28, at the mRNA and protein levels." target gene hsa-mir-16 "Leukemia, Myeloid, Acute" 22970245 our data demonstrated that over-expression of miR-16 mimics suppressed Pim-1 expression in FD-FLT3/ITD cells suggesting that increased miR-16 expression contributes to depletion of Pim-1 after FLT3 inhibition and that miR-16 repression may be associated with up-regulated Pim-1 in FLT3/ITD expressing cells. target gene hsa-mir-101 Lung Neoplasms 22977606 Overexpression of miR-101 induced a marked reduction in EZH2 mRNA levels in several lung cancer cell lines target gene hsa-mir-200c Melanoma 22982443 miR-200c inhibits melanoma progression and drug resistance through down-regulation of BMI-1. target gene hsa-mir-10a "Carcinoma, Hepatocellular" 22996586 Our findings highlight the importance of miR-10a in regulating the metastatic properties of HCC by directly targeting EphA4 and may provide new insights into the pathogenesis of HCC target gene hsa-mir-34a Breast Neoplasms 23001043 Our results demonstrate that miR-34a/c functions as a metastasis suppressor to regulate breast cancer migration and invasion through targeting Fra-1 oncogene and suggest a therapeutic application of miR-34 in breast cancer. target gene hsa-mir-34c Breast Neoplasms 23001043 Our results demonstrate that miR-34a/c functions as a metastasis suppressor to regulate breast cancer migration and invasion through targeting Fra-1 oncogene and suggest a therapeutic application of miR-34 in breast cancer. target gene hsa-mir-494 "Carcinoma, Lung, Non-Small-Cell" 23012423 MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation. target gene hsa-mir-125a Myeloproliferative Neoplasms 23012470 "we demonstrate that miR-125a targets multiple protein phosphatases. Our data demonstrate that miR-125a-induced MPN is addicted to its sustained overexpression, and highlight the complex nature of oncogenic miRNA dependence in an early neoplastic state." target gene hsa-let-7c Bladder Neoplasms 23013190 "Expression of 5 miRNAs (miR-34a, let-7c, miR-16, miR-103b, and miR-106b) that target p53, Rb, or Bcl-2 protein pathways was determined for bladder samples and cells via quantitative real-time PCR assay." target gene hsa-mir-103b Bladder Neoplasms 23013190 "Expression of 5 miRNAs (miR-34a, let-7c, miR-16, miR-103b, and miR-106b) that target p53, Rb, or Bcl-2 protein pathways was determined for bladder samples and cells via quantitative real-time PCR assay." target gene hsa-mir-106b Bladder Neoplasms 23013190 "Expression of 5 miRNAs (miR-34a, let-7c, miR-16, miR-103b, and miR-106b) that target p53, Rb, or Bcl-2 protein pathways was determined for bladder samples and cells via quantitative real-time PCR assay." target gene hsa-mir-16 Bladder Neoplasms 23013190 "Expression of 5 miRNAs (miR-34a, let-7c, miR-16, miR-103b, and miR-106b) that target p53, Rb, or Bcl-2 protein pathways was determined for bladder samples and cells via quantitative real-time PCR assay." target gene hsa-mir-34a Bladder Neoplasms 23013190 "Expression of 5 miRNAs (miR-34a, let-7c, miR-16, miR-103b, and miR-106b) that target p53, Rb, or Bcl-2 protein pathways was determined for bladder samples and cells via quantitative real-time PCR assay." target gene hsa-mir-135a "Carcinoma, Rectal" 23017832 MiR-135a promotes growth and invasion of colorectal cancer via metastasis suppressor 1 in vitro. target gene hsa-mir-146a Psoriasis 23018031 Inability of miR-146a inhibiting target gene IRAK1 may contribute to the persistent inflammation in lesions of psoriasis. target gene hsa-mir-200c Vascular Hypertrophy 23020145 "Increased miR-21 and miR-200c contents were associated with reduced expression of their targets, Sprouty-1 and ZEB2, respectively." target gene hsa-mir-21 Vascular Hypertrophy 23020145 "Increased miR-21 and miR-200c contents were associated with reduced expression of their targets, Sprouty-1 and ZEB2, respectively." target gene hsa-mir-128 "Leukemia, Myeloid, Acute" 23022987 "A Renilla-luciferase assay and flow cytometry after transfection with pre-microRNAs confirmed that RET is regulated by miR-218, miR-128, miR-27b, miR-15a and miR-195." target gene hsa-mir-15a "Leukemia, Myeloid, Acute" 23022987 "A Renilla-luciferase assay and flow cytometry after transfection with pre-microRNAs confirmed that RET is regulated by miR-218, miR-128, miR-27b, miR-15a and miR-195." target gene hsa-mir-195 "Leukemia, Myeloid, Acute" 23022987 "A Renilla-luciferase assay and flow cytometry after transfection with pre-microRNAs confirmed that RET is regulated by miR-218, miR-128, miR-27b, miR-15a and miR-195." target gene hsa-mir-218 "Leukemia, Myeloid, Acute" 23022987 "A Renilla-luciferase assay and flow cytometry after transfection with pre-microRNAs confirmed that RET is regulated by miR-218, miR-128, miR-27b, miR-15a and miR-195." target gene hsa-mir-27b "Leukemia, Myeloid, Acute" 23022987 "A Renilla-luciferase assay and flow cytometry after transfection with pre-microRNAs confirmed that RET is regulated by miR-218, miR-128, miR-27b, miR-15a and miR-195." target gene hsa-mir-1 Heart Failure 23024758 "Time-course analysis revealed that decreased expression of miR-1 and miR-133a commences at a pre-disease stage, and precedes upregulation of target genes causal of cardiac hypertrophy and extracellular matrix remodelling, suggesting a role for miR-1 and miR-133a in early disease development." target gene hsa-mir-133a Heart Failure 23024758 "Time-course analysis revealed that decreased expression of miR-1 and miR-133a commences at a pre-disease stage, and precedes upregulation of target genes causal of cardiac hypertrophy and extracellular matrix remodelling, suggesting a role for miR-1 and miR-133a in early disease development." target gene hsa-mir-155 Atherosclerosis 23041630 MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages target gene hsa-mir-141 Ovarian Neoplasms 23045278 miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells target gene hsa-mir-145 Breast Neoplasms 23049906 MiR-145 regulates epithelial to mesenchymal transition of breast cancer cells by targeting Oct4 target gene hsa-mir-1280 Urinary Bladder Cancer 23056431 MicroRNA-1280 inhibits invasion and metastasis by targeting ROCK1 in bladder cancer target gene hsa-mir-17 Leukemia 23056458 we demonstrated that physiological re-expression of exogenous miR-17 and miR-20a are able to partially rescue the proliferation loss induced by Fli-1 knock-down and identified HBP1 as a target of these miRNA in erythroleukemic cells. target gene hsa-mir-20a Leukemia 23056458 we demonstrated that physiological re-expression of exogenous miR-17 and miR-20a are able to partially rescue the proliferation loss induced by Fli-1 knock-down and identified HBP1 as a target of these miRNA in erythroleukemic cells. target gene hsa-mir-122 Breast Neoplasms 23056576 MiR-122 inhibits cell proliferation and tumorigenesis of breast cancer by targeting IGF1R target gene hsa-mir-17 "Leukemia, Myeloid" 23059786 HIF-1a downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation target gene hsa-mir-20a "Leukemia, Myeloid" 23059786 HIF-1a downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation target gene hsa-mir-153-1 Prostate Neoplasms 23060044 Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer target gene hsa-mir-153-2 Prostate Neoplasms 23060044 Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer target gene hsa-mir-214 "Carcinoma, Hepatocellular" 23068095 MiR-214 inhibits cell growth in hepatocellular carcinoma through suppression of beta-catenin target gene hsa-mir-198 Prostate Neoplasms 23069480 Livin expression may be regulated by miR-198 in human prostate cancer cell lines target gene hsa-mir-124-1 Prostate Neoplasms 23069658 Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells target gene hsa-mir-124-2 Prostate Neoplasms 23069658 Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells target gene hsa-mir-124-3 Prostate Neoplasms 23069658 Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells target gene hsa-mir-133a Cardiac Myocyte Injury 23069713 We also discovered that luciferase activity is exclusively decreased by targeting EGFR in hMSCs transfected with miR-133a mimic. These results suggest that EGFR plays a key role in the regulation of cardiogenic differentiation in hMSCs. target gene hsa-mir-1297 Lung Neoplasms 23071539 miR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2 target gene hsa-mir-511 Lung Neoplasms 23071539 miR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2 target gene hsa-mir-101-1 Breast Neoplasms 23071542 MiR-101 is involved in human breast carcinogenesis by targeting Stathmin1 target gene hsa-mir-101-2 Breast Neoplasms 23071542 MiR-101 is involved in human breast carcinogenesis by targeting Stathmin1 target gene hsa-mir-203 Lung Neoplasms 23073851 miR-203 negatively regulates survivin protein expression and inhibits the proliferation and invasion of lung cancer cells target gene hsa-mir-145 Glioma 23076445 MiR-145 reduces ADAM17 expression and inhibits in vitro migration and invasion of glioma cells target gene hsa-mir-125a "Carcinoma, Hepatocellular" 23079745 SIRT7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors mir-125a-5p and mir-125b target gene hsa-mir-125b-1 "Carcinoma, Hepatocellular" 23079745 SIRT7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors mir-125a-5p and mir-125b target gene hsa-mir-125b-2 "Carcinoma, Hepatocellular" 23079745 SIRT7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors mir-125a-5p and mir-125b target gene hsa-mir-21 Neuroblastoma 23084187 Micro-RNA-21 regulates the sensitivity to cisplatin in human neuroblastoma cells target gene hsa-mir-34a Breast Neoplasms 23085450 MicroRNA-34a modulates chemosensitivity of breast cancer cells to adriamycin by targeting Notch1 target gene hsa-mir-181a-1 Neoplasms [unspecific] 23085757 "miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer" target gene hsa-mir-181a-2 Neoplasms [unspecific] 23085757 "miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer" target gene hsa-mir-199a-1 Neoplasms [unspecific] 23085757 "miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer" target gene hsa-mir-199a-2 Neoplasms [unspecific] 23085757 "miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer" target gene hsa-mir-30d Neoplasms [unspecific] 23085757 "miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer" target gene hsa-mir-17 Prostate Neoplasms 23095762 miR-17-5p targets the p300/CBP-associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells target gene hsa-mir-26a-1 "Leukemia, Myeloid, Acute" 23096114 The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells target gene hsa-mir-26a-2 "Leukemia, Myeloid, Acute" 23096114 The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells target gene hsa-mir-181a-2 "Leukemia, Myeloid, Acute" 23100311 Lenalidomide-mediated enhanced translation of C/EBPalpha-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia target gene hsa-mir-133a Ischemia-Reperfusion Injury 23102905 "Therefore, targeting of microRNA-133a represents a potentially novel means for regulating the cascade of profibrotic events after ischemia-reperfusion." target gene hsa-mir-15a Multiple Myeloma 23104180 miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF target gene hsa-mir-16-1 Multiple Myeloma 23104180 miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF target gene hsa-mir-16-2 Multiple Myeloma 23104180 miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF target gene hsa-mir-143 Urinary Bladder Cancer 23104321 Replacement treatment with microRNA-143 and -145 induces synergistic inhibition of the growth of human bladder cancer cells by regulating PI3K/Akt and MAPK signaling pathways target gene hsa-mir-145 Urinary Bladder Cancer 23104321 Replacement treatment with microRNA-143 and -145 induces synergistic inhibition of the growth of human bladder cancer cells by regulating PI3K/Akt and MAPK signaling pathways target gene hsa-mir-21 Laryngeal Neoplasms 23104547 Downregulation of miR-21 regulates MMP-2 expression and suppress migration of Laryngeal squamous cell carcinoma target gene hsa-mir-210 Neuroblastoma 23108914 MicroRNA-210 targets antiapoptotic Bcl-2 expression and mediates hypoxia-induced apoptosis of neuroblastoma cells target gene hsa-mir-26a-1 Esophageal Neoplasms 23108995 MiR-26a regulates cell cycle and anoikis of human esophageal adenocarcinoma cells through Rb1-E2F1 signaling pathway target gene hsa-mir-26a-2 Esophageal Neoplasms 23108995 MiR-26a regulates cell cycle and anoikis of human esophageal adenocarcinoma cells through Rb1-E2F1 signaling pathway target gene hsa-mir-429 Colorectal Carcinoma 23111103 MiR-429 is an independent prognostic factor in colorectal cancer and exerts its anti-apoptotic function by targeting SOX2 target gene hsa-mir-29a Osteosarcoma 23113351 data obtained highlight the role of miRNA-29a in the regulation of osteoblastic cell apoptosis by silencing Bcl-2 and Mcl-1 and inducing E2F1 and E2F3 expression target gene hsa-mir-29a "Leukemia, Myeloid, Chronic-Phase" 23113544 Regulation of Human RNase-L by the miR-29 Family Reveals a Novel Oncogenic Role in Chronic Myelogenous Leukemia target gene hsa-mir-29b-1 "Leukemia, Myeloid, Chronic-Phase" 23113544 Regulation of Human RNase-L by the miR-29 Family Reveals a Novel Oncogenic Role in Chronic Myelogenous Leukemia target gene hsa-mir-29b-2 "Leukemia, Myeloid, Chronic-Phase" 23113544 Regulation of Human RNase-L by the miR-29 Family Reveals a Novel Oncogenic Role in Chronic Myelogenous Leukemia target gene hsa-mir-27a Lung Neoplasms 23117485 miR-27a regulates the self renewal of the H446 small cell lung cancer cell line in vitro target gene hsa-mir-144 Nasopharyngeal Neoplasms 23125220 "MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN" target gene hsa-mir-205 Parkinson Disease 23125283 MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein target gene hsa-mir-17 Sarcoma [unspecific] 23128393 "Interestingly, the levels of onco-miR-17 locus coded miRNAs (miR-17-5p and miR-20a) were decreased upon TAF15 depletion and shown to affect the post-transcriptional regulation of TAF15-dependent genes,such as CDKN1A/p21." target gene hsa-mir-20a Sarcoma [unspecific] 23128393 "Interestingly, the levels of onco-miR-17 locus coded miRNAs (miR-17-5p and miR-20a) were decreased upon TAF15 depletion and shown to affect the post-transcriptional regulation of TAF15-dependent genes,such as CDKN1A/p21." target gene hsa-mir-574 Lung Neoplasms 23133627 MicroRNA-574-5p was pivotal for TLR9 signaling enhanced tumor progression via down-regulating checkpoint suppressor 1 in human lung cancer target gene hsa-mir-7-1 Lung Neoplasms 23135998 "MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway" target gene hsa-mir-7-2 Lung Neoplasms 23135998 "MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway" target gene hsa-mir-7-3 Lung Neoplasms 23135998 "MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway" target gene hsa-let-7a Ovarian Neoplasms 23136250 The hsa-let-7 family member hsa-let-7a is a modulator of KLK6 protein expression that is independent of the KLK6 copy number status. target gene hsa-mir-186 Colorectal Carcinoma 23137536 "miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells" target gene hsa-mir-216b Colorectal Carcinoma 23137536 "miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells" target gene hsa-mir-337 Colorectal Carcinoma 23137536 "miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells" target gene hsa-mir-760 Colorectal Carcinoma 23137536 "miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells" target gene hsa-mir-196a-1 Colorectal Carcinoma 23138850 "miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells" target gene hsa-mir-196a-2 Colorectal Carcinoma 23138850 "miR-186, miR-216b, miR-337-3p, and miR-760 cooperatively induce cellular senescence by targeting alpha subunit of protein kinase CKII in human colorectal cancer cells" target gene hsa-mir-197 Pancreatic Neoplasms 23139153 MiR-197 induces epithelial-mesenchymal transition in pancreatic cancer cells by targeting p120 catenin target gene hsa-mir-1 Heart Failure 23141496 Biochemical assays and an inducible cardiac-specific transgenic mouse model overexpressing miR-1 were used to demonstrate that heart-type fatty acid-binding protein-3 (FABP3) is a target of miR-1. target gene hsa-mir-1-1 Lung Neoplasms 23142026 MicroRNA-1 targets Slug and endows lung cancer A549 cells with epithelial and anti-tumorigenic properties target gene hsa-mir-1-2 Lung Neoplasms 23142026 MicroRNA-1 targets Slug and endows lung cancer A549 cells with epithelial and anti-tumorigenic properties target gene hsa-mir-152 Glioma 23142217 MiR-15b and miR-152 reduce glioma cell invasion and angiogenesis via NRP-2 and MMP-3 target gene hsa-mir-15b Glioma 23142217 MiR-15b and miR-152 reduce glioma cell invasion and angiogenesis via NRP-2 and MMP-3 target gene hsa-mir-24-1 Glioma 23142218 MiR-24 regulates the proliferation and invasion of glioma by ST7L via beta-catenin/Tcf-4 signaling target gene hsa-mir-24-2 Glioma 23142218 MiR-24 regulates the proliferation and invasion of glioma by ST7L via beta-catenin/Tcf-4 signaling target gene hsa-mir-517a "Carcinoma, Hepatocellular" 23142219 Down-regulation of miR-517a and miR-517c promotes proliferation of hepatocellular carcinoma cells via targeting Pyk2 target gene hsa-mir-517c "Carcinoma, Hepatocellular" 23142219 Down-regulation of miR-517a and miR-517c promotes proliferation of hepatocellular carcinoma cells via targeting Pyk2 target gene hsa-mir-27a Cardiomyopathy 23143062 MicroRNA-27a regulates cardiomyocytic apoptosis during cardioplegia-induced cardiac arrest by targeting interleukin 10-related pathways target gene hsa-mir-135b Colorectal Carcinoma 23143558 Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-beta in colorectal cells target gene hsa-mir-146a Ischemia-Reperfusion Injury 23143987 MicroRNA-146a-mediated downregulation of IRAK1 protects mouse and human small intestine against ischemia/reperfusion injury. target gene hsa-mir-149 Gastric Neoplasms 23144691 MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer target gene hsa-mir-550a-1 "Carcinoma, Hepatocellular" 23145039 MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic polyadenylation element-binding protein 4 in hepatocellular carcinoma target gene hsa-mir-550a-2 "Carcinoma, Hepatocellular" 23145039 MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic polyadenylation element-binding protein 4 in hepatocellular carcinoma target gene hsa-mir-550a-3 "Carcinoma, Hepatocellular" 23145039 MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic polyadenylation element-binding protein 4 in hepatocellular carcinoma target gene hsa-mir-100 Lung Neoplasms 23151088 MicroRNA-100 is a potential molecular marker of non-small cell lung cancer and functions as a tumor suppressor by targeting polo-like kinase 1 target gene hsa-mir-137 Melanoma 23151846 miR-137 Inhibits the Invasion of Melanoma Cells through Downregulation of Multiple Oncogenic Target Genes target gene hsa-mir-204 Gastric Neoplasms 23152059 miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer target gene hsa-mir-182 Human Immunodeficiency Virus Infection 23153509 Down-regulation of NAMPT expression by miR-182 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation target gene hsa-mir-1-1 Cardiomegaly 23156720 Effects of microRNA-1 on negatively regulating L-type calcium channel beta2 subunit gene expression during cardiac hypertrophy target gene hsa-mir-1-2 Cardiomegaly 23156720 Effects of microRNA-1 on negatively regulating L-type calcium channel beta2 subunit gene expression during cardiac hypertrophy target gene hsa-mir-200c Urinary Bladder Cancer 23159064 "Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2,9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells" target gene hsa-mir-21 Wounds and Injuries [unspecific] 23159215 miR-21 regulates skin wound healing by targeting multiple aspects of the healing process target gene hsa-mir-218-1 "Squamous Cell Carcinoma, Head and Neck" 23159910 Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma target gene hsa-mir-218-2 "Squamous Cell Carcinoma, Head and Neck" 23159910 Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma target gene hsa-mir-125b-1 Urinary Bladder Cancer 23160634 MiR-125b Inhibits Tumor Growth and Promotes Apoptosis of Cervical Cancer Cells by Targeting Phosphoinositide 3-Kinase Catalytic Subunit Delta target gene hsa-mir-125b-2 Urinary Bladder Cancer 23160634 MiR-125b Inhibits Tumor Growth and Promotes Apoptosis of Cervical Cancer Cells by Targeting Phosphoinositide 3-Kinase Catalytic Subunit Delta target gene hsa-mir-195 Osteosarcoma 23162665 microRNA-195 suppresses osteosarcoma cell invasion and migration in vitro by targeting FASN target gene hsa-mir-133a-1 Cardiomegaly 23166348 Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy target gene hsa-mir-133a-2 Cardiomegaly 23166348 Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy target gene hsa-mir-361 "Squamous Cell Carcinoma, Skin or Unspecific" 23166713 The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinoma target gene hsa-mir-222 Colorectal Carcinoma 23173124 "On the other hand, miR-222 targeting ADAM-17, a disintegrin and metalloproteinase, and miR-328 interacting with ABCG2, an ABC transporter, may overcome drug resistance of cancer cells." target gene hsa-mir-29a Colorectal Carcinoma 23173124 "microRNA levels may serve as a predictive CRC marker, which was confirmed by the serum level of miR-29a targeting KLF4, a marker of cell stemness, and the plasma level of miR-221 down-regulating c-Kit, Stat5A and ETS1, which are signal transducers and transcription factor, respectively" target gene hsa-mir-21 Colorectal Carcinoma 23174819 MiR-21 regulates biological behavior through the PTEN/PI-3 K/Akt signaling pathway in human colorectal cancer cells target gene hsa-mir-16-1 Glioma 23175429 Zyxin may be one of putative target genes of miR-16-1 target gene hsa-mir-16-2 Glioma 23175429 Zyxin may be one of putative target genes of miR-16-1 target gene hsa-mir-657 "Carcinoma, Hepatocellular" 23175432 MiR-657 promotes tumorigenesis in hepatocellular carcinoma by targeting transducin-like enhancer protein 1 through NF-kB pathways target gene hsa-mir-15a Neuroblastoma 23176145 MicroRNA-15a promotes neuroblastoma migration by targeting reversion-inducing cysteine-rich protein with Kazal motifs (RECK) and regulating matrix metalloproteinase-9 expression target gene hsa-mir-135a-1 "Carcinoma, Renal Cell" 23176581 Tumor-suppressive microRNA-135a inhibits cancer cell proliferation by targeting the c-MYC oncogene in renal cell carcinoma target gene hsa-mir-135a-2 "Carcinoma, Renal Cell" 23176581 Tumor-suppressive microRNA-135a inhibits cancer cell proliferation by targeting the c-MYC oncogene in renal cell carcinoma target gene hsa-mir-21 Pancreatic Neoplasms 23177026 "The serum miR-21 level serves as a predictor for the chemosensitivity of advanced pancreatic cancer, and miR-21 expression confers chemoresistance by targeting FasL" target gene hsa-mir-137 Lung Neoplasms 23178712 miR-137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6 target gene hsa-mir-101-1 Neoplasms [unspecific] 23178713 MicroRNA-101 suppresses SOX9-dependent tumorigenicity and promotes favorable prognosis of human hepatocellular carcinoma target gene hsa-mir-101-2 Neoplasms [unspecific] 23178713 MicroRNA-101 suppresses SOX9-dependent tumorigenicity and promotes favorable prognosis of human hepatocellular carcinoma target gene hsa-mir-137 Neoplasms [unspecific] 23178914 miR-137 restoration sensitizes multidrug-resistant MCF-7/ADM cells to anticancer agents by targeting YB-1 target gene hsa-mir-1290 Breast Neoplasms 23183268 MiR-1290 and its potential targets are associated with characteristics of estrogen receptor alpha-positive breast cancer target gene hsa-mir-133a-1 Liver Cirrhosis 23183523 miR-133a mediates TGF-beta-dependent de-repression of collagen-synthesis in hepatic stellate cells during liver fibrosis target gene hsa-mir-133a-2 Liver Cirrhosis 23183523 miR-133a mediates TGF-beta-dependent de-repression of collagen-synthesis in hepatic stellate cells during liver fibrosis target gene hsa-mir-302a Urinary Bladder Cancer 23185040 The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1 target gene hsa-mir-367 Urinary Bladder Cancer 23185040 The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1 target gene hsa-mir-214 Glioma 23187003 microRNA-214-mediated UBC9 expression in glioma target gene hsa-mir-320a Prostate Neoplasms 23188675 MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway target gene hsa-mir-98 Prostate Neoplasms 23188821 Identification of microRNA-98 as a Therapeutic Target Inhibiting Prostate Cancer Growth and a Biomarker Induced by Vitamin D target gene hsa-mir-23b "Carcinoma, Renal Cell" 23189187 Inhibition of PTEN gene expression by oncogenic miR-23b-3p in renal cancer target gene hsa-mir-17 Pancreatic Neoplasms 23194063 "The mechanism of curcumin-/RL197-induced repression of Sp transcription factors was ROS-dependent and due to induction of the Sp repressors ZBTB10 and ZBTB4 and downregulation of microRNAs (miR)-27a, miR-20a and miR-17-5p that regulate these repressors." target gene hsa-mir-20a Pancreatic Neoplasms 23194063 "The mechanism of curcumin-/RL197-induced repression of Sp transcription factors was ROS-dependent and due to induction of the Sp repressors ZBTB10 and ZBTB4 and downregulation of microRNAs (miR)-27a, miR-20a and miR-17-5p that regulate these repressors." target gene hsa-mir-27a Pancreatic Neoplasms 23194063 "The mechanism of curcumin-/RL197-induced repression of Sp transcription factors was ROS-dependent and due to induction of the Sp repressors ZBTB10 and ZBTB4 and downregulation of microRNAs (miR)-27a, miR-20a and miR-17-5p that regulate these repressors." target gene hsa-mir-320a Myasthenia Gravis 23196978 MiR-320a is Downregulated in Patients with Myasthenia Gravis and Modulates Inflammatory Cytokines Production by Targeting Mitogen-activated Protein Kinase 1 target gene hsa-mir-200b Endometrial Neoplasms 23205572 MicroRNA-200b Is Overexpressed in Endometrial Adenocarcinomas and Enhances MMP2 Activity by Downregulating TIMP2 in Human Endometrial Cancer Cell Line HEC-1A Cells target gene hsa-mir-133a-1 Urinary Bladder Cancer 23206218 "MicroRNA-133 inhibits cell proliferation, migration and invasion by targeting epidermal growth factor receptor and its downstream effector proteins in bladder cancer" target gene hsa-mir-133a-2 Urinary Bladder Cancer 23206218 "MicroRNA-133 inhibits cell proliferation, migration and invasion by targeting epidermal growth factor receptor and its downstream effector proteins in bladder cancer" target gene hsa-mir-133b Urinary Bladder Cancer 23206218 "MicroRNA-133 inhibits cell proliferation, migration and invasion by targeting epidermal growth factor receptor and its downstream effector proteins in bladder cancer" target gene hsa-mir-375 Lung Neoplasms 23206448 miR-375 is a novel prognostic indicator in NSCLC and might be a potential target for diagnosis and gene therapy target gene hsa-mir-7-1 Melanoma 23206698 "miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling" target gene hsa-mir-7-2 Melanoma 23206698 "miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling" target gene hsa-mir-7-3 Melanoma 23206698 "miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling" target gene hsa-mir-10b Endometriosis 23206733 Targeting of syndecan-1 by micro-ribonucleic acid miR-10b modulates invasiveness of endometriotic cells via dysregulation of the proteolytic milieu and interleukin-6 secretion target gene hsa-mir-21 "Carcinoma, Renal Cell" 23206776 miR-21 Downregulated TCF21 to Inhibit KISS1 in Renal Cancer target gene hsa-mir-223 Osteosarcoma 23208072 Heat Shock Protein 90B1 Plays an Oncogenic Role and is a Target of microRNA-223 in Human Osteosarcoma target gene hsa-mir-7-1 Colorectal Carcinoma 23208495 microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis target gene hsa-mir-7-2 Colorectal Carcinoma 23208495 microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis target gene hsa-mir-7-3 Colorectal Carcinoma 23208495 microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis target gene hsa-mir-200a Breast Neoplasms 23209748 miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression target gene hsa-mir-200b Breast Neoplasms 23209748 miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression target gene hsa-mir-200c Breast Neoplasms 23209748 miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression target gene hsa-mir-98 Neoplasms [unspecific] 23211491 MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11 target gene hsa-mir-150 Cardiomegaly 23211718 miR-150 regulates high glucose-induced cardiomyocyte hypertrophy by targeting the transcriptional co-activator p300 target gene hsa-mir-205 "Carcinoma, Oral" 23212344 "MicroRNA-205 directly regulates the tumor suppressor, interleukin-24, in human KB oral cancer cells" target gene hsa-mir-218-1 Medulloblastoma 23212916 MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype associated genes in medulloblastoma target gene hsa-mir-218-2 Medulloblastoma 23212916 MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype associated genes in medulloblastoma target gene hsa-mir-145 Neuroblastoma 23222716 "MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha" target gene hsa-mir-30c-1 Breast Neoplasms 23224145 MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion. target gene hsa-mir-30c-2 Breast Neoplasms 23224145 MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion. target gene hsa-mir-16-1 "Carcinoma, Hepatocellular" 23226427 Cyclooxygenase-2 Is a Target of MicroRNA-16 in Human Hepatoma Cells target gene hsa-mir-16-2 "Carcinoma, Hepatocellular" 23226427 Cyclooxygenase-2 Is a Target of MicroRNA-16 in Human Hepatoma Cells target gene hsa-mir-182 Urinary Bladder Cancer 23226455 Oncogenic miRNA-182-5p Targets Smad4 and RECK in Human Bladder Cancer target gene hsa-mir-21 "Carcinoma, Endometrioid Endometrial" 23226804 microRNA-21 overexpression contributes to cell proliferation by targeting PTEN in endometrioid endometrial cancer target gene hsa-mir-383 Medulloblastoma 23227829 MiR-383 is Downregulated in Medulloblastoma and Targets Peroxiredoxin 3 (PRDX3) target gene hsa-mir-125b-1 "Carcinoma, Oral" 23230394 "Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins" target gene hsa-mir-125b-2 "Carcinoma, Oral" 23230394 "Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins" target gene hsa-mir-203 "Carcinoma, Oral" 23230394 "Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins" target gene hsa-mir-21 "Carcinoma, Oral" 23230394 "Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins" target gene hsa-mir-370 "Carcinoma, Oral" 23231387 miR-370 modulates insulin receptor substrate-1 expression and inhibits the tumor phenotypes of oral carcinoma target gene hsa-mir-335 Lung Neoplasms 23232114 Genetic variation in a miR-335 binding site in BIRC5 alters susceptibility to lung cancer in Chinese Han populations target gene hsa-mir-145 Gastric Neoplasms 23233482 "microRNA-145 targets v-ets erythroblastosis virus E26 oncogene homolog 1 to suppress the invasion, metastasis and angiogenesis of gastric cancer cells" target gene hsa-mir-148b Breast Neoplasms 23233531 "miR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS,and CSF1" target gene hsa-mir-31 Psoriasis 23233723 MicroRNA-31 Is Overexpressed in Psoriasis and Modulates Inflammatory Cytokine and Chemokine Production in Keratinocytes via Targeting Serine/Threonine Kinase 40 target gene hsa-mir-596 "Carcinoma, Oral" 23233740 Potential of tumor-suppressive miR-596 targeting LGALS3BP as a therapeutic agent in oral cancer target gene hsa-mir-27a "Leukemia, Myeloid, Acute" 23236401 MiR-27a Functions as a Tumor Suppressor in Acute Leukemia by Regulating 14-3-3 target gene hsa-mir-372 Gastric Neoplasms 23242208 microRNA-372 maintains oncogene characteristics by targeting TNFAIP1 and affects NFkB signaling in human gastric carcinoma cells target gene hsa-mir-218-1 Glioma 23243056 MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-kB activity target gene hsa-mir-218-2 Glioma 23243056 MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-kB activity target gene hsa-mir-29a Melanoma 23245396 Interferon-gamma-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells target gene hsa-mir-29b-1 Melanoma 23245396 Interferon-gamma-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells target gene hsa-mir-29b-2 Melanoma 23245396 Interferon-gamma-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells target gene hsa-mir-17 Myelodysplastic Syndromes 23246221 "Expression analysis of mir-17-5p, mir-20a and let-7a microRNAs and their target proteins in CD34+ bone marrow cells of patients with myelodysplastic syndromes" target gene hsa-mir-20a Myelodysplastic Syndromes 23246221 "Expression analysis of mir-17-5p, mir-20a and let-7a microRNAs and their target proteins in CD34+ bone marrow cells of patients with myelodysplastic syndromes" target gene hsa-mir-363 Head And Neck Neoplasms 23246488 Dysregulated miR-363 affects head and neck cancer invasion and metastasis by targeting podoplanin target gene hsa-mir-18a Glioblastoma 23249750 Targeting of TGFbeta signature and its essential component CTGF by miR-18 correlates with improved survival in glioblastoma target gene hsa-mir-143 Glioma 23250070 Rapamycin inhibits human glioma cell proliferation through down-regulating mammalian target of rapamycin pathway and up-regulating microRNA-143 target gene hsa-mir-17 Colorectal Carcinoma 23250421 Elevated oncofoetal miR-17-5p expression regulates colorectal cancer progression by repressing its target gene P130 target gene hsa-mir-124-1 Breast Neoplasms 23250910 MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer target gene hsa-mir-124-2 Breast Neoplasms 23250910 MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer target gene hsa-mir-124-3 Breast Neoplasms 23250910 MiR-124 targets Slug to regulate epithelial-mesenchymal transition and metastasis of breast cancer target gene hsa-mir-145 Choriocarcinoma 23251245 Cell proliferation and invasion ability of human choriocarcinoma cells lessened due to inhibition of Sox2 expression by microRNA-145 target gene hsa-mir-137 Oligodendroglioma 23252729 "MIR-137 Suppresses Growth and Invasion, is Downregulated in Oligodendroglial Tumors and Targets CSE1L" target gene hsa-mir-21 Cholangiocarcinoma 23254774 "These data indicated that TPM1 is downregulated in HuCCT1 cells and that the Ras signaling pathway as well as DNA methylation, histone deacetylation and miR-21 upregulation play important roles in the suppression of TPM1 expression in HuCCT1 cells. Thus, compounds that inhibit genetic and epigenetic mechanisms may be promising agents in treating cholangiocarcinoma." target gene hsa-mir-24-1 Glioma 23254855 miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1 target gene hsa-mir-24-2 Glioma 23254855 miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1 target gene hsa-mir-27a Glioma 23254855 miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1 target gene hsa-mir-218-1 Colon Neoplasms 23255074 MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating oncogene BMI-1 target gene hsa-mir-218-2 Colon Neoplasms 23255074 MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating oncogene BMI-1 target gene hsa-mir-491 Acute Cerebral Infarction 23257658 A functional polymorphism at miR-491-5p binding site in the 3'-UTR of MMP-9 gene confers increased risk for atherosclerotic cerebral infarction in a Chinese population target gene hsa-mir-31 Colon Neoplasms 23258531 miR-31 acts as an oncogene in colon cancer and identified RhoBTB1 as a new target of miR-31 further study demonstrated that miR-31 contributed to the development of colon cancer at least partly by targeting RhoBTB1 target gene hsa-mir-122 Atherosclerosis 23260873 "Several miRNAs have been described to finely regulate lipid metabolism and the progression and regression of atherosclerosis including, miR-33, miR-122." target gene hsa-mir-33 Atherosclerosis 23260873 "Several miRNAs have been described to finely regulate lipid metabolism and the progression and regression of atherosclerosis including, miR-33, miR-122." target gene hsa-mir-424 Hypertension 23263626 An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension target gene hsa-mir-503 Hypertension 23263626 An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension target gene hsa-mir-34a Gastric Neoplasms 23264087 Expression and regulatory function of miRNA-34a in targeting survivin in gastric cancer cells target gene hsa-mir-501 Hepatitis B Virus Infection 23266610 MicroRNA-501 promotes HBV replication by targeting HBXIP target gene hsa-let-7d Ovarian Neoplasms 23268403 Construction of let-7d expression vector and its inhibitory effect on HMGA2 and ras expression in human ovarian cancer cells in vitro target gene hsa-mir-100 Urinary Bladder Cancer 23270926 MicroRNA-100 inhibits human bladder urothelial carcinogenesis by directly targeting mTOR target gene hsa-mir-21 "Lymphoma, Large B-Cell, Diffuse" 23275230 MicroRNA-21 regulates the sensitivity of diffuse large B-cell lymphoma cells to the CHOP chemotherapy regimen target gene hsa-mir-362 Colorectal Carcinoma 23280316 "MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer" target gene hsa-mir-182 Urinary Bladder Cancer 23284967 Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells target gene hsa-mir-183 Urinary Bladder Cancer 23284967 Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells target gene hsa-mir-210 Urinary Bladder Cancer 23284967 Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells target gene hsa-mir-96 Urinary Bladder Cancer 23284967 Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells target gene hsa-mir-126 "Colitis, Ulcerative" 23285182 Up-Regulation of microRNA-126 May Contribute to Pathogenesis of Ulcerative Colitis via Regulating NF-kappaB Inhibitor I§Ø¨mB§Ø©ã target gene hsa-mir-9-1 Nasopharyngeal Neoplasms 23291181 miR-9 modulates the expression of interferon-regulated genes and MHC class I molecules in human nasopharyngeal carcinoma cells target gene hsa-mir-9-2 Nasopharyngeal Neoplasms 23291181 miR-9 modulates the expression of interferon-regulated genes and MHC class I molecules in human nasopharyngeal carcinoma cells target gene hsa-mir-100 Esophageal Neoplasms 23292834 MicroRNA-99a/100 promotes apoptosis by targeting mTOR in human esophageal squamous cell carcinoma target gene hsa-mir-99a Esophageal Neoplasms 23292834 MicroRNA-99a/100 promotes apoptosis by targeting mTOR in human esophageal squamous cell carcinoma target gene hsa-mir-196b Endometriosis 23293219 "miR-196b targets c-myc and Bcl-2 expression, inhibits proliferation and induces apoptosis in endometriotic stromal cells" target gene hsa-mir-133b Gastric Neoplasms 23296701 miR-133b acts as a tumor suppressor and negatively regulates FGFR1 in gastric cancer target gene hsa-mir-199b Breast Neoplasms 23296799 MiR-199b-5p targets HER2 in breast cancer cells target gene hsa-mir-182 Ovarian Neoplasms 23296900 "MicroRNA-182 promotes cell growth, invasion and chemoresistance by targeting programmed cell death 4 (PDCD4) in human ovarian carcinomas" target gene hsa-mir-149 Glioma 23298478 MicroRNA-149 inhibits proliferation and invasion of glioma cells via blockade of AKT1 signaling target gene hsa-mir-107 Glioma 23299462 MicroRNA-107 inhibits glioma cell migration and invasion by modulating Notch2 expression target gene hsa-mir-150 Esophageal Neoplasms 23301507 MiR-150 regulates the EMT-inducer ZEB1 in esophageal squamous cell carcinoma.Wound healing assays of premiR-150-treated esophageal squamous cell carcinoma TE-8 cells target gene hsa-mir-16-1 Ovarian Neoplasms 23302126 "MicroRNA-16 regulates the proliferation, invasion and apoptosis of ovarian epithelial carcinoma cells in vitro" target gene hsa-mir-16-2 Ovarian Neoplasms 23302126 "MicroRNA-16 regulates the proliferation, invasion and apoptosis of ovarian epithelial carcinoma cells in vitro" target gene hsa-mir-34b Pancreatic Neoplasms 23305226 MicroRNA-34b inhibits pancreatic cancer metastasis through repressing Smad3 target gene hsa-mir-636 "Carcinoma, Hepatocellular" 23306701 "ANT2 suppression by shRNA restores miR-636 expression, thereby downregulating Ras and inhibiting tumorigenesis of hepatocellular carcinoma" target gene hsa-mir-145 Endometriosis 23312222 "MicroRNA miR-145 inhibits proliferation, invasiveness, and stem cell phenotype of an in vitro endometriosis model by targeting multiple cytoskeletal elements and pluripotency factors" target gene hsa-mir-34a Osteosarcoma 23314380 miR-34a inhibits the metastasis of osteosarcoma cells by repressing the expression of CD44. target gene hsa-mir-384 Myocardial Ischemic-Reperfusion Injury 23315007 "MicroRNA-384-5p regulates ischemia-induced cardioprotection by targeting phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (PI3Kp110§Ø©¤)" target gene hsa-mir-152 Ovarian Neoplasms 23318422 MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine target gene hsa-mir-185 Ovarian Neoplasms 23318422 MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine target gene hsa-mir-138 "Squamous Cell Carcinoma, Esophageal" 23319823 Downregulation of miR-138 sustains NF-¦ÊB activation and promotes lipid raft formation in esophageal squamous cell carcinoma. target gene hsa-mir-18a Gastric Neoplasms 23322197 MicroRNA-18a modulates STAT3 activity through negative regulation of PIAS3 during gastric adenocarcinogenesis target gene hsa-mir-31 Colorectal Carcinoma 23322774 MicroRNA-31 activates the Ras pathway and functions as an oncogenic microRNA in human colorectal cancer by repressing RAS p21 GTPase activating protein 1(RASA1). target gene hsa-mir-30a "Cardiomyopathy, Hypertrophic" 23326547 miR-30a induced alterations in beclin-1 gene expression and autophagy in cardiomyocytes. target gene hsa-mir-122 Infertility 23327642 MicroRNA-122 influences the development of sperm abnormalities from human induced pluripotent stem cells by regulating TNP2 expression. target gene hsa-mir-182 Prostate Neoplasms 23329838 MicroRNA-182 and microRNA-200a control G-protein subunit alpha-13 (GNA13) expression and cell invasion synergistically in prostate cancer cells. target gene hsa-mir-200a Prostate Neoplasms 23329838 MicroRNA-182 and microRNA-200a control G-protein subunit alpha-13 (GNA13) expression and cell invasion synergistically in prostate cancer cells. target gene hsa-mir-221 Coronary Artery Disease 23333386 "Overall, these findings demonstrate that miR-221 affects the MEK/ERK pathway by targeting PAK1 to inhibit the proliferation of EPCs." target gene hsa-mir-182 Breast Neoplasms 23333633 Up-regulation of miR-182 by beta-catenin in breast cancer increases tumorigenicity and invasiveness by targeting the matrix metalloproteinase inhibitor RECK target gene hsa-mir-193b Neoplasms [unspecific] 23335975 MicroRNA-193b enhances tumor progression via down regulation of neurofibromin 1 target gene hsa-mir-330 Colorectal Carcinoma 23337504 miR-330 regulates the proliferation of colorectal cancer cells by targeting Cdc42 target gene hsa-mir-301a Gastric Neoplasms 23338485 Overexpressed miR-301a promotes cell proliferation and invasion by targeting RUNX3 in gastric cancer target gene hsa-mir-200a Breast Neoplasms 23340296 MicroRNA-200a Promotes Anoikis Resistance and Metastasis by Targeting YAP1 in Human Breast Cancer target gene hsa-let-7a Head And Neck Neoplasms 23340306 "miR-21, miR-31, miR-504 and miR-10b are important oncogenic miRNAs that are involved in HNSCC and target tumour suppressor genes. The tumour suppressor roles of the let-7 family, the miR-99 family, miR-107, miR-133a, miR-137, miR-138 and miR-375 with respect to their targeting of oncogenes are unequivocal and have been confirmed by many studies." target gene hsa-let-7b Head And Neck Neoplasms 23340306 "miR-21, miR-31, miR-504 and miR-10b are important oncogenic miRNAs that are involved in HNSCC and target tumour suppressor genes. The tumour suppressor roles of the let-7 family, the miR-99 family, miR-107, miR-133a, miR-137, miR-138 and miR-375 with respect to their targeting of oncogenes are unequivocal and have been confirmed by many studies." target gene hsa-let-7c Head And Neck Neoplasms 23340306 "miR-21, miR-31, miR-504 and miR-10b are important oncogenic miRNAs that are involved in HNSCC and target tumour suppressor genes. The tumour suppressor roles of the let-7 family, the miR-99 family, miR-107, miR-133a, miR-137, miR-138 and miR-375 with respect to their targeting of oncogenes are unequivocal and have been confirmed by many studies." target gene hsa-let-7d Head And Neck Neoplasms 23340306 "miR-21, miR-31, miR-504 and miR-10b are important oncogenic miRNAs that are involved in HNSCC and target tumour suppressor genes. The tumour suppressor roles of the let-7 family, the miR-99 family, miR-107, miR-133a, miR-137, miR-138 and miR-375 with respect to their targeting of oncogenes are unequivocal and have been confirmed by many studies." target gene hsa-let-7e Head And Neck Neoplasms 23340306 "miR-21, miR-31, miR-504 and miR-10b are important oncogenic miRNAs that are involved in HNSCC and target tumour suppressor genes. The tumour suppressor roles of the let-7 family, the miR-99 family, miR-107, miR-133a, miR-137, miR-138 and miR-375 with respect to their targeting of oncogenes are unequivocal and have been confirmed by many studies." target gene hsa-let-7f Head And Neck Neoplasms 23340306 "miR-21, miR-31, miR-504 and miR-10b are important oncogenic miRNAs that are involved in HNSCC and target tumour suppressor genes. The tumour suppressor roles of the let-7 family, the miR-99 family, miR-107, miR-133a, miR-137, miR-138 and miR-375 with respect to their targeting of oncogenes are unequivocal and have been confirmed by many studies." target gene hsa-let-7g Head And Neck Neoplasms 23340306 "miR-21, miR-31, miR-504 and miR-10b are important oncogenic miRNAs that are involved in HNSCC and target tumour suppressor genes. The tumour suppressor roles of the let-7 family, the miR-99 family, miR-107, miR-133a, miR-137, miR-138 and miR-375 with respect to their targeting of oncogenes are unequivocal and have been confirmed by many studies." target gene hsa-let-7i Head And Neck Neoplasms 23340306 "miR-21, miR-31, miR-504 and miR-10b are important oncogenic miRNAs that are involved in HNSCC and target tumour suppressor genes. The tumour suppressor roles of the let-7 family, the miR-99 family, miR-107, miR-133a, miR-137, miR-138 and miR-375 with respect to their targeting of oncogenes are unequivocal and have been confirmed by many studies." target gene hsa-mir-10b Head And Neck Neoplasms 23340306 "miR-21, miR-31, miR-504 and miR-10b are important oncogenic miRNAs that are involved in HNSCC and target tumour suppressor genes. The tumour suppressor roles of the let-7 family, the miR-99 family, miR-107, miR-133a, miR-137, miR-138 and miR-375 with respect to their targeting of oncogenes are unequivocal and have been confirmed by many studies." target gene hsa-mir-21 Head And Neck Neoplasms 23340306 "miR-21, miR-31, miR-504 and miR-10b are important oncogenic miRNAs that are involved in HNSCC and target tumour suppressor genes. The tumour suppressor roles of the let-7 family, the miR-99 family, miR-107, miR-133a, miR-137, miR-138 and miR-375 with respect to their targeting of oncogenes are unequivocal and have been confirmed by many studies." target gene hsa-mir-31 Head And Neck Neoplasms 23340306 "miR-21, miR-31, miR-504 and miR-10b are important oncogenic miRNAs that are involved in HNSCC and target tumour suppressor genes. The tumour suppressor roles of the let-7 family, the miR-99 family, miR-107, miR-133a, miR-137, miR-138 and miR-375 with respect to their targeting of oncogenes are unequivocal and have been confirmed by many studies." target gene hsa-mir-504 Head And Neck Neoplasms 23340306 "miR-21, miR-31, miR-504 and miR-10b are important oncogenic miRNAs that are involved in HNSCC and target tumour suppressor genes. The tumour suppressor roles of the let-7 family, the miR-99 family, miR-107, miR-133a, miR-137, miR-138 and miR-375 with respect to their targeting of oncogenes are unequivocal and have been confirmed by many studies." target gene hsa-mir-30c-1 Breast Neoplasms 23340433 MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11 target gene hsa-mir-30c-2 Breast Neoplasms 23340433 MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11 target gene hsa-mir-138-1 Lung Neoplasms 23343715 MiR-138 Inhibits Tumor Growth Through Repression of EZH2 in Non-Small Cell Lung Cancer target gene hsa-mir-138-2 Lung Neoplasms 23343715 MiR-138 Inhibits Tumor Growth Through Repression of EZH2 in Non-Small Cell Lung Cancer target gene hsa-mir-206 Gastric Neoplasms 23348698 MiR-206 inhibits gastric cancer proliferation in part by repressing CyclinD2 target gene hsa-mir-30a Glioma 23348703 PRDM1 is directly targeted by miR-30a-5p and modulates the Wnt/beta-catenin pathway in a Dkk1-dependent manner during glioma growth target gene hsa-mir-34a Lung Neoplasms 23349340 "Ectopic expression of miR-34a enhances radiosensitivity of non-small cell lung cancer cells, partly by suppressing the LyGDI signaling pathway" target gene hsa-mir-22 Huntington Disease 23349832 MicroRNA-22 (miR-22) Overexpression Is Neuroprotective via General Anti-Apoptotic Effects and May also Target Specific Huntington's Disease-Related Mechanisms target gene hsa-mir-296 Gastric Neoplasms 23353818 MicroRNA-296-5p increases proliferation in gastric cancer through repression of Caudal-related homeobox 1 target gene hsa-mir-155 Breast Neoplasms 23353819 Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cance target gene hsa-mir-145 Prostate Neoplasms 23355420 HEF1 promotes epithelial mesenchymal transition and bone invasion in prostate cancer under the regulation of microRNA-145 target gene hsa-mir-21 Pancreatic Neoplasms 23359184 Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression target gene hsa-mir-24 Breast Neoplasms 23359482 "Downregulation of HR genes correlated with increased levels of their predicted microRNAs (miRNAs), miR-183 (predicted target RAD50) and miR-24 (predicted target BRCA1), suggesting that PE may regulate miRNAs involved in DNA repair processes." target gene hsa-mir-199a-1 Cardiomyopathy 23360823 TWIST1 regulates the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy target gene hsa-mir-199a-2 Cardiomyopathy 23360823 TWIST1 regulates the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy target gene hsa-mir-199b Cardiomyopathy 23360823 TWIST1 regulates the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy target gene hsa-mir-214 Cardiomyopathy 23360823 TWIST1 regulates the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy target gene hsa-mir-34a Neoplasms [unspecific] 23361983 Modeling miRNA Regulation in Cancer Signaling Systems: miR-34a Regulation of the p53/Sirt1 Signaling Module target gene hsa-mir-31 Breast Neoplasms 23364795 microRNA-31 sensitizes human breast cells to apoptosis by direct targeting of protein kinase C epsilon target gene hsa-mir-100 Pancreatic Neoplasms 23373509 MicroRNA-100 regulates IGF1-receptor expression in metastatic pancreatic cancer cells target gene hsa-mir-122 Liver Neoplasms 23373973 Effect of miR-122 and its target gene cationic amino acid transporter 1 on colorectal liver metastasis target gene hsa-mir-26b Breast Neoplasms 23374284 MiRNA-26b inhibits proliferation by targeting PTGS2 in breast cancer target gene hsa-mir-106b Glioma 23377830 miR-106b facilitates glioma cell growth by promoting cell cycle progression through the negative regulation of RBL2 target gene hsa-mir-16-1 Colorectal Carcinoma 23380758 microRNA-16 represses colorectal cancer cell growth in vitro by regulating the p53/survivin signaling pathway target gene hsa-mir-16-2 Colorectal Carcinoma 23380758 microRNA-16 represses colorectal cancer cell growth in vitro by regulating the p53/survivin signaling pathway target gene hsa-mir-200a Gastric Neoplasms 23381389 Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/beta-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma target gene hsa-mir-195 Glioma 23383003 MicroRNA-195 Inhibits the Proliferation of Human Glioma Cells by Directly Targeting Cyclin D1 and Cyclin E1 target gene hsa-mir-30a Glioma 23383034 MiR-30a-5p Antisense Oligonucleotide Suppresses Glioma Cell Growth by Targeting SEPT7 target gene hsa-mir-182 Prostate Neoplasms 23383207 "MicroRNA-182-5p Promotes Cell Invasion and Proliferation by Down Regulating FOXF2, RECK and MTSS1 Genes in Human Prostate Cancer" target gene hsa-mir-9-1 Gastric Neoplasms 23383271 "microRNA-9 Suppresses the Proliferation, Invasion and Metastasis of Gastric Cancer Cells through Targeting Cyclin D1 and Ets1" target gene hsa-mir-9-2 Gastric Neoplasms 23383271 "microRNA-9 Suppresses the Proliferation, Invasion and Metastasis of Gastric Cancer Cells through Targeting Cyclin D1 and Ets1" target gene hsa-mir-9-3 Gastric Neoplasms 23383271 "microRNA-9 Suppresses the Proliferation, Invasion and Metastasis of Gastric Cancer Cells through Targeting Cyclin D1 and Ets1" target gene hsa-mir-143 Prostate Neoplasms 23383988 Up-regulated microRNA-143 in cancer stem cells differentiation promotes prostate cancer cells metastasis by modulating FNDC3B expression target gene hsa-mir-7-1 Breast Neoplasms 23384942 miR-7 Suppresses Brain Metastasis of Breast Cancer Stem-Like Cells By Modulating KLF4 target gene hsa-mir-7-2 Breast Neoplasms 23384942 miR-7 Suppresses Brain Metastasis of Breast Cancer Stem-Like Cells By Modulating KLF4 target gene hsa-mir-7-3 Breast Neoplasms 23384942 miR-7 Suppresses Brain Metastasis of Breast Cancer Stem-Like Cells By Modulating KLF4 target gene hsa-mir-138-1 Ovarian Neoplasms 23389731 MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1a target gene hsa-mir-138-2 Ovarian Neoplasms 23389731 MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1a target gene hsa-mir-26a-1 "Carcinoma, Hepatocellular" 23389848 MicroRNA-26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting IL-6-Stat3 pathway target gene hsa-mir-26a-2 "Carcinoma, Hepatocellular" 23389848 MicroRNA-26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting IL-6-Stat3 pathway target gene hsa-mir-145 Glioma 23390502 MicroRNA-145 Is Downregulated in Glial Tumors and Regulates Glioma Cell Migration by Targeting Connective Tissue Growth Factor target gene hsa-mir-17 Glioblastoma 23391506 Stress Response of Glioblastoma Cells Mediated by miR-17-5p Targeting PTEN and the Passenger Strand miR-17-3p Targeting MDM2 target gene hsa-mir-145 Urinary Bladder Cancer 23392170 "socs7, a target gene of microRNA-145, regulates interferon-alpha induction through STAT3 nuclear translocation in bladder cancer cells" target gene hsa-mir-130b Endometrial Neoplasms 23392577 miR-130b is an EMT-related microRNA that targets DICER1 for aggression in endometrial cancer target gene hsa-mir-130a Colorectal Carcinoma 23393589 The Oncogenic Role of microRNA-130a/301a/454 in Human Colorectal Cancer via Targeting Smad4 Expression target gene hsa-mir-301a Colorectal Carcinoma 23393589 The Oncogenic Role of microRNA-130a/301a/454 in Human Colorectal Cancer via Targeting Smad4 Expression target gene hsa-mir-454 Colorectal Carcinoma 23393589 The Oncogenic Role of microRNA-130a/301a/454 in Human Colorectal Cancer via Targeting Smad4 Expression target gene hsa-mir-17 Ovarian Neoplasms 23396109 Downregulation of miR-17~92 Expression Increase Paclitaxel Sensitivity in Human Ovarian Carcinoma SKOV3-TR30 Cells via BIM Instead of PTEN target gene hsa-mir-92a-1 Ovarian Neoplasms 23396109 Downregulation of miR-17~92 Expression Increase Paclitaxel Sensitivity in Human Ovarian Carcinoma SKOV3-TR30 Cells via BIM Instead of PTEN target gene hsa-mir-92a-2 Ovarian Neoplasms 23396109 Downregulation of miR-17~92 Expression Increase Paclitaxel Sensitivity in Human Ovarian Carcinoma SKOV3-TR30 Cells via BIM Instead of PTEN target gene hsa-mir-224 Inflammatory Bowel Diseases 23399735 MicroRNA-224 Negatively Regulates p21 Expression During Late Neoplastic Progression in Inflammatory Bowel Disease target gene hsa-mir-137 Neuroblastoma 23400681 "miR-137 directly targets KDM1A mRNA in neuroblastoma cells, and activates cell properties consistent with tumor suppression" target gene hsa-mir-140 "Carcinoma, Hepatocellular" 23401231 MicroRNA-140-5p suppresses tumor growth and metastasis by targeting TGFBR1 and FGF9 in hepatocellular carcinoma target gene hsa-mir-34c Endometrial Neoplasms 23412924 "Furthermore, miR-34c mimics significantly enhanced apoptosis in Ishikawa cells by inhibiting IL-6R expression. Therefore, a combination of miR-34c mimics and DDP could be an effective therapeutic strategy for controlling Ishikawa cell proliferation." target gene hsa-mir-92b Glioma 23416699 miR-92b controls glioma proliferation and invasion through regulating Wnt/beta-catenin signaling via Nemo-like kinase target gene hsa-mir-125b-1 Head And Neck Neoplasms 23416980 Loss of miR-125b-1 contributes to head and neck cancer development by dysregulating TACSTD2 and MAPK pathway target gene hsa-mir-125b-2 Head And Neck Neoplasms 23416980 Loss of miR-125b-1 contributes to head and neck cancer development by dysregulating TACSTD2 and MAPK pathway target gene hsa-mir-185 Prostate Neoplasms 23417242 "MicroRNA-185 suppresses proliferation, invasion, migration, and tumorigenicity of human prostate cancer cells through targeting androgen receptor" target gene hsa-mir-21 Liver Cirrhosis 23417858 Overexpression of microRNA-21 regulating PDCD4 during tumorigenesis of liver fluke-associated cholangiocarcinoma contributes to tumor growth and metastasis target gene hsa-mir-17 "Carcinoma, Hepatocellular" 23418359 "Mature MiR-17-5p and passenger miR-17-3p induce hepatocellular carcinoma by targeting PTEN, GalNT7, and vimentin in different signal pathways" target gene hsa-mir-24-1 Neoplasms [unspecific] 23418360 MicroRNA miR-24 Enhances Tumor Invasion and Metastasis by Targeting PTPN9 and PTPRF to Promote EGF Signaling target gene hsa-mir-24-2 Neoplasms [unspecific] 23418360 MicroRNA miR-24 Enhances Tumor Invasion and Metastasis by Targeting PTPN9 and PTPRF to Promote EGF Signaling target gene hsa-mir-320d-1 Kaposi Sarcoma 23418466 Cellular MicroRNAs 498 and 320d Regulate Herpes Simplex Virus 1 Induction of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by Targeting RTA target gene hsa-mir-320d-2 Kaposi Sarcoma 23418466 Cellular MicroRNAs 498 and 320d Regulate Herpes Simplex Virus 1 Induction of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by Targeting RTA target gene hsa-mir-498 Kaposi Sarcoma 23418466 Cellular MicroRNAs 498 and 320d Regulate Herpes Simplex Virus 1 Induction of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by Targeting RTA target gene hsa-mir-34c Gastric Neoplasms 23423488 Regulation of microtubule-associated protein tau (MAPT) by miR-34c-5p determines the chemosensitivity of gastric cancer to paclitaxel target gene hsa-mir-125b-1 Urinary Bladder Cancer 23425975 microRNA-125b inhibits cell migration and invasion by targeting matrix metallopeptidase 13 in bladder cancer target gene hsa-mir-125b-2 Urinary Bladder Cancer 23425975 microRNA-125b inhibits cell migration and invasion by targeting matrix metallopeptidase 13 in bladder cancer target gene hsa-mir-34a Acute Myocardial Infarction 23426265 "these results identify age-induced expression of miR-34a and inhibition of its target PNUTS as a key mechanism that regulates cardiac contractile function during ageing and after acute myocardial infarction, by inducing DNA damage responses and telomere attrition." target gene hsa-mir-154 Prostate Neoplasms 23428540 miR-154 inhibits prostate cancer cell proliferation by targeting CCND2 target gene hsa-mir-570 Gastric Neoplasms 23430453 A miR-570 binding site polymorphism in the B7-H1 gene is associated with the risk of gastric adenocarcinoma target gene hsa-mir-182 Breast Neoplasms 23430586 Expression and regulatory function of miRNA-182 in triple-negative breast cancer cells through its targeting of profilin 1 target gene hsa-mir-181b-1 Glioma 23431408 MiRNA-181b suppresses IGF-1R and functions as a tumor suppressor gene in gliomas target gene hsa-mir-181b-2 Glioma 23431408 MiRNA-181b suppresses IGF-1R and functions as a tumor suppressor gene in gliomas target gene hsa-mir-25 Colorectal Carcinoma 23435373 MicroRNA-25 functions as a potential tumor suppressor in colon cancer by targeting Smad7 target gene hsa-mir-146a Gastric Neoplasms 23435376 MicroRNA-146a acts as a metastasis suppressor in gastric cancer by targeting WASF2 target gene hsa-mir-1 Heart Failure 23436819 The decrease of miR-1 and increase of AnxA5 appear as important modulators of NCX1 expression and activity during heart failure. target gene hsa-mir-155 Laryngeal Neoplasms 23437123 Overexpression of miR -155 Promotes Proliferation and Invasion of Human Laryngeal Squamous Cell Carcinoma via Targeting SOCS1 and STAT3 target gene hsa-mir-23a "Adenocarcinoma, Lung" 23437179 "Among them, we confirmed TGF-¦Â-mediated induction of miR-23a in lung epithelial cell lines,target genes of which were further identified by gene expression profiling." target gene hsa-mir-126 Melanoma 23437250 miR-126&126* Restored Expressions Play a Tumor Suppressor Role by Directly Regulating ADAM9 and MMP7 in Melanoma target gene hsa-mir-27a Ovarian Neoplasms 23438830 Oncogenic MicroRNA-27a is a Target for Genistein in Ovarian Cancer Cells target gene hsa-mir-135a-1 Neoplasms [unspecific] 23438844 "MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells" target gene hsa-mir-135a-2 Neoplasms [unspecific] 23438844 "MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells" target gene hsa-mir-138-1 Neoplasms [unspecific] 23438844 "MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells" target gene hsa-mir-138-2 Neoplasms [unspecific] 23438844 "MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells" target gene hsa-mir-181b "Adenocarcinoma, Pancreatic Ductal" 23440261 miRNA-181b increases the sensitivity of pancreatic ductal adenocarcinoma cells to gemcitabine in vitro and in nude mice by targeting BCL-2. target gene hsa-mir-145 "Carcinoma, Renal Cell" 23441135 MicroRNA-145 Targets the Metalloprotease ADAM17 and Is Suppressed in Renal Cell Carcinoma Patients target gene hsa-mir-29c Gastric Neoplasms 23442884 MiR-29c is downregulated in gastric carcinomas and regulates cell proliferation by targeting RCC2 target gene hsa-mir-30a Breast Neoplasms 23445407 MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells target gene hsa-mir-21 Multiple Myeloma 23446999 Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth target gene hsa-mir-378a Cardiomegaly 23447532 "A cardiac enriched microRNA, miR-378 blocks cardiac hypertrophy by targeting Ras-signaling" target gene hsa-mir-210 "Carcinoma, Renal Cell" 23449350 "miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis" target gene hsa-mir-27a Hepatitis C Virus Infection 23449803 MicroRNA-27a regulates lipid metabolism and inhibits hepatitis C virus replication in human hepatoma cells target gene hsa-mir-23a Endometriosis 23450049 MicroRNA23a and MicroRNA23b Deregulation Derepresses SF-1 and Upregulates Estrogen Signaling in Ovarian Endometriosis target gene hsa-mir-23b Endometriosis 23450049 MicroRNA23a and MicroRNA23b Deregulation Derepresses SF-1 and Upregulates Estrogen Signaling in Ovarian Endometriosis target gene hsa-mir-30a Systemic Lupus Erythematosus 23450709 MicroRNA-30a promotes B cell hyperactivity in patient with SLE by direct interaction with LYN target gene hsa-mir-133b Prostate Neoplasms 23451058 "miR-133b is directly up-regulated by AR, and represses CDC2L5, PTPRK, RB1CC1, and CPNE3, respectively. Moreover, we found miR-133b is essential to PCa cell survival. " target gene hsa-mir-19a Prostate Neoplasms 23451058 "miR-19a is directly up-regulated by AR, and represses SUZ12, RAB13, SC4MOL, PSAP and ABCA1, respectively. " target gene hsa-mir-27a Prostate Neoplasms 23451058 "miR-27a is directly up-regulated by AR, and represses ABCA1 and PDS5B. " target gene hsa-mir-497 Urinary Bladder Cancer 23453369 MicroRNA-497 is a potential prognostic marker in human cervical cancer and functions as a tumor suppressor by targeting the insulin-like growth factor 1 receptor target gene hsa-let-7i "Squamous Cell Carcinoma, Head and Neck" 23454123 "In clinical HNSCC samples, let-7i expression was inversely correlated with BMP4 expression. Our results revealed that let-7i attenuates mesenchymal-mode migration of HNSCC cells through repression of a novel target, BMP4." target gene hsa-mir-218-1 "Carcinoma, Renal Cell" 23454155 microRNA-218 inhibits cell migration and invasion in renal cell carcinoma through targeting caveolin-2 involved in focal adhesion pathway target gene hsa-mir-218-2 "Carcinoma, Renal Cell" 23454155 microRNA-218 inhibits cell migration and invasion in renal cell carcinoma through targeting caveolin-2 involved in focal adhesion pathway target gene hsa-mir-146a Thyroid Neoplasms 23457043 MicroRNA-146a targets PRKCE to modulate papillary thyroid tumor development target gene hsa-mir-152 Prostate Neoplasms 23460133 miR-152 controls migration and invasive potential by targeting TGF¦Á in prostate cancer cell lines target gene hsa-mir-21 Gastric Neoplasms 23466500 miR-21 confers cisplatin resistance in gastric cancer cells by regulating PTEN target gene hsa-mir-134 Glioblastoma 23467648 MiR-134 regulates the proliferation and invasion of glioblastoma cells by reducing Nanog expression target gene hsa-mir-195 "Carcinoma, Hepatocellular" 23468064 "MicroRNA-195 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting the expression of VEGF, VAV2 and CDC42" target gene hsa-mir-3148 Systemic Lupus Erythematosus 23468661 MicroRNA-3148 Modulates Allelic Expression of Toll-Like Receptor 7 Variant Associated with Systemic Lupus Erythematosus target gene hsa-mir-216a "Carcinoma, Hepatocellular" 23471579 MiR-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer target gene hsa-mir-217 "Carcinoma, Hepatocellular" 23471579 MiR-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer target gene hsa-mir-27a Colorectal Carcinoma 23471840 The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis target gene hsa-mir-183 Sensorineural Hearing Loss 23472202 The miR-183/Taok1 target pair is implicated in cochlear responses to acoustic trauma. target gene hsa-mir-182 Breast Neoplasms 23474751 Suppression of MIM by microRNA-182 activates RhoA and promotes breast cancer metastasis target gene hsa-mir-486 Lung Neoplasms 23474761 Downregulation of miR-486-5p contributes to tumor progression and metastasis by targeting protumorigenic ARHGAP5 in lung cancer target gene hsa-mir-214 Nasopharyngeal Neoplasms 23479198 miR-214 promotes tumorigenesis by targeting lactotransferrin in nasopharyngeal carcinoma target gene hsa-mir-21 Cholangiocarcinoma 23480766 "The expression level of miR-21 had an inverse correlation with the mRNA level of its target RECK, a metastasis suppressor, in human CCA" target gene hsa-mir-145 Prostate Neoplasms 23480797 The proto-oncogene ERG is a target of microRNA miR-145 in prostate cancer target gene hsa-mir-218-1 Cervical Neoplasms 23483249 Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion by targeting focal adhesion pathways in cervical squamous cell carcinoma target gene hsa-mir-218-2 Cervical Neoplasms 23483249 Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion by targeting focal adhesion pathways in cervical squamous cell carcinoma target gene hsa-mir-30a Colorectal Carcinoma 23486085 miR-30a Suppresses Cell Migration and Invasion Through Downregulation of PIK3CD in Colorectal Carcinoma target gene hsa-mir-195 "Carcinoma, Hepatocellular" 23487264 Genome-wide screening revealed that miR-195 targets the TNF-alpha/NF-kB pathway by downregulating IKK and TAB3 in hepatocellular carcinoma target gene hsa-mir-205 Neoplasms [unspecific] 23487795 Arf tumor suppressor and miR-205 regulate cell adhesion and formation of extraembryonic endoderm from pluripotent stem cells target gene hsa-mir-93 Breast Neoplasms 23492819 MicroRNA-93 regulates NRF2 expression and is associated with breast carcinogenesis. target gene hsa-mir-29b-1 "Leukemia, Myeloid, Acute" 23493348 Targeted Delivery of microRNA-29b by Transferrin Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia target gene hsa-mir-29b-2 "Leukemia, Myeloid, Acute" 23493348 Targeted Delivery of microRNA-29b by Transferrin Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia target gene hsa-mir-93 Polycystic Ovarian Syndrome 23493574 miRNA-93 inhibits GLUT4 and is overexpressed in adipose tissue of Polycystic Ovary Syndrome patients and women with insulin resistance target gene hsa-mir-145 Colorectal Carcinoma 23499891 Tumor-suppressive microRNA-145 targets catenin to regulate Wnt/beta-catenin signaling in human colon cancer cells target gene hsa-mir-145 "Carcinoma, Hepatocellular" 23499894 MiR-145 functions as a tumor suppressor by directly targeting histone deacetylase 2 in liver cancer target gene hsa-mir-21 Esophageal Neoplasms 23504349 "miR-21 Down-Regulation Suppresses Cell Growth, Invasion and Induces Cell Apoptosis by Targeting FASL, TIMP3, and RECK Genes in Esophageal Carcinoma" target gene hsa-mir-16-1 Osteosarcoma 23507142 miR-16 inhibits cell proliferation by targeting IGF1R and the Raf1-MEK1/2-ERK1/2 pathway in osteosarcoma target gene hsa-mir-16-2 Osteosarcoma 23507142 miR-16 inhibits cell proliferation by targeting IGF1R and the Raf1-MEK1/2-ERK1/2 pathway in osteosarcoma target gene hsa-mir-30e Renal Fibrosis 23515048 A microRNA-30e/mitochondrial uncoupling protein 2 axis mediates TGF-¦Â1-induced tubular epithelial cell extracellular matrix production and kidney fibrosis. target gene hsa-mir-181a Inflammation 23516523 we provide the first evidence for anti-inflammatory effects of miR-181a mediated at least in part by down-regulating IL1a. target gene hsa-mir-150 Lymphoma 23521217 Re-expression of miR-150 induces EBV-positive Burkitt lymphoma differentiation by modulating c-Myb in vitro target gene hsa-mir-9 Inflammation 23525285 MicroRNA-9 regulates the expression of peroxisome proliferator-activated receptor ¦Ä in human monocytes during the inflammatory response. target gene hsa-mir-195 Colorectal Carcinoma 23526568 MicroRNA-195 chemosensitizes colon cancer cells to the chemotherapeutic drug doxorubicin by targeting the first binding site of BCL2L2 mRNA target gene hsa-mir-128-1 Breast Neoplasms 23526655 Downregulation of miRNA-128 sensitizes breast cancer cell to chemodrugs by targeting Bax target gene hsa-mir-128-2 Breast Neoplasms 23526655 Downregulation of miRNA-128 sensitizes breast cancer cell to chemodrugs by targeting Bax target gene hsa-mir-22 Gastric Neoplasms 23529765 "miR-22 is down-regulated in gastric cancer, and its overexpression inhibits cell migration and invasion via targeting transcription factor Sp1" target gene hsa-mir-9-1 Breast Neoplasms 23530058 miR-9-3p targets integrin beta 1 to sensitize claudin-low breast cancer cells to MEK inhibition target gene hsa-mir-9-2 Breast Neoplasms 23530058 miR-9-3p targets integrin beta 1 to sensitize claudin-low breast cancer cells to MEK inhibition target gene hsa-mir-9-3 Breast Neoplasms 23530058 miR-9-3p targets integrin beta 1 to sensitize claudin-low breast cancer cells to MEK inhibition target gene hsa-mir-497 Neuroblastoma 23531080 MicroRNA-497 increases apoptosis in MYCN amplified neuroblastoma cells by targeting the key cell cycle regulator WEE1 target gene hsa-mir-34a Neoplasms [unspecific] 23533633 "CD24 Induces Expression of the Oncomir miR-21 via Src, and CD24 and Src Are Both Post-Transcriptionally Downregulated by the Tumor Suppressor miR-34a" target gene hsa-mir-148a Asthma 23534973 These combined results are consistent with +3142 allele-specific targeting of HLA-G by the miR-152 family and support our hypothesis that miRNA regulation of sHLA-G in the airway is influenced by both the asthma status of the subject's mother and the subject's genotype. target gene hsa-mir-148b Asthma 23534973 These combined results are consistent with +3142 allele-specific targeting of HLA-G by the miR-152 family and support our hypothesis that miRNA regulation of sHLA-G in the airway is influenced by both the asthma status of the subject's mother and the subject's genotype. target gene hsa-mir-152 Asthma 23534973 These combined results are consistent with +3142 allele-specific targeting of HLA-G by the miR-152 family and support our hypothesis that miRNA regulation of sHLA-G in the airway is influenced by both the asthma status of the subject's mother and the subject's genotype. target gene hsa-mir-183 Prostate Neoplasms 23538390 microRNA-183 is an oncogene targeting Dkk-3 and SMAD4 in prostate cancer target gene hsa-mir-31 Neoplasms [unspecific] 23539435 MicroRNA-31-5p modulates cell cycle by targeting human mutL homolog 1 in human cancer cells target gene hsa-mir-200b Glioma 23543137 MicroRNA-200b targets CREB1 and suppresses cell growth in human malignant glioma target gene hsa-mir-195 "Carcinoma, Hepatocellular" 23544130 The Tumor-Suppressive miR-497-195 Cluster Targets Multiple Cell-Cycle Regulators in Hepatocellular Carcinoma target gene hsa-mir-497 "Carcinoma, Hepatocellular" 23544130 The Tumor-Suppressive miR-497-195 Cluster Targets Multiple Cell-Cycle Regulators in Hepatocellular Carcinoma target gene hsa-mir-145 Head And Neck Neoplasms 23548270 miR145 targets the SOX9/ADAM17 axis to inhibit tumor initiating cells and IL-6-mediated paracrine effects in head and neck cancer target gene hsa-mir-148a Gastric Neoplasms 23549984 MicroRNA-148a can regulate runt-related transcription factor 3 gene expression via modulation of DNA methyltransferase 1 in gastric cancer target gene hsa-mir-139 Glioma 23551751 MiR-139 Inhibits Mcl-1 Expression and Potentiates TMZ-Induced Apoptosis in Glioma target gene hsa-mir-15a Leukemia 23551855 miR-15a/16-1 is known to regulate Bcl2 in chronic lymphocytic leukemia target gene hsa-mir-16-1 Leukemia 23551855 miR-15a/16-1 is known to regulate Bcl2 in chronic lymphocytic leukemia target gene hsa-mir-23a Gastric Neoplasms 23553990 MiR-23a in Amplified 19p13.13 Loci Targets Metallothionein 2A and Promotes Growth in Gastric Cancer Cells target gene hsa-mir-874 "Squamous Cell Carcinoma, Head and Neck" 23558898 Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma target gene hsa-mir-21 "Carcinoma, Renal Cell" 23558936 "MiR-21 is overexpressed in RCC tissue and modulates the growth, apoptosis and cell cycle progression of RCC cells and regulates the expression of PDCD4 and TPM1" target gene hsa-mir-205 "Carcinoma, Nasopharyngeal" 23564023 "Our research group established the radioresistant NPC cell line CNE2R derived from the CNE2 cell line, and demonstrated that irradiation-induced miR-205 determined the resistance of NPC through directly targeting PTEN." target gene hsa-mir-383 Glioma 23564324 Downregulation of miR-383 promotes glioma cell invasion by targeting insulin-like growth factor 1 receptor target gene hsa-mir-34a Osteosarcoma 23569431 MicroRNA-34a Inhibits Human Osteosarcoma Proliferation by Downregulating Ether go-go 1 Expression target gene hsa-mir-205 Prostate Neoplasms 23571738 miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients target gene hsa-mir-155 Viral Infectious Disease 23572582 "NK cells constitutively expressing Noxa and SOCS1 exhibit profound defects in expansion during the response to MCMV infection, suggesting that their regulation by miR-155 promotes antiviral immunity." target gene hsa-mir-370 Gastric Neoplasms 23576572 Fork head box M1 is overexpressed in Helicobacter pylori-induced gastric carcinogenesis and is negatively regulated by hsa-miR-370 target gene hsa-mir-24-1 Osteosarcoma 23578572 MicroRNA-24 Inhibits Osteosarcoma Cell Proliferation Both In Vitro and In Vivo by Targeting LPAAT target gene hsa-mir-24-2 Osteosarcoma 23578572 MicroRNA-24 Inhibits Osteosarcoma Cell Proliferation Both In Vitro and In Vivo by Targeting LPAAT target gene hsa-mir-193a Ovarian Neoplasms 23588298 We demonstrated that miR-193a decreased the amount of MCL1 protein by binding 3'UTR of its mRNA. target gene hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 23597135 "Here we review studies that provide evidence suggesting that certain miRNAs (e.g. miR-155, miR-17-92, miR-181, miR-29) can regulate the activated phenotype of CLL cells and/or fitness of the surface-immunoglobulin (sIg) B cell receptor (BCR) complex expressed by CLL cells, thereby accounting for the differential leukemia-cell expression of these miRNAs in different CLL prognostic subgroups." target gene hsa-mir-17 "Leukemia, Lymphocytic, Chronic, B-Cell" 23597135 "Here we review studies that provide evidence suggesting that certain miRNAs (e.g. miR-155, miR-17-92, miR-181, miR-29) can regulate the activated phenotype of CLL cells and/or fitness of the surface-immunoglobulin (sIg) B cell receptor (BCR) complex expressed by CLL cells, thereby accounting for the differential leukemia-cell expression of these miRNAs in different CLL prognostic subgroups." target gene hsa-mir-18 "Leukemia, Lymphocytic, Chronic, B-Cell" 23597135 "Here we review studies that provide evidence suggesting that certain miRNAs (e.g. miR-155, miR-17-92, miR-181, miR-29) can regulate the activated phenotype of CLL cells and/or fitness of the surface-immunoglobulin (sIg) B cell receptor (BCR) complex expressed by CLL cells, thereby accounting for the differential leukemia-cell expression of these miRNAs in different CLL prognostic subgroups." target gene hsa-mir-181 "Leukemia, Lymphocytic, Chronic, B-Cell" 23597135 "Here we review studies that provide evidence suggesting that certain miRNAs (e.g. miR-155, miR-17-92, miR-181, miR-29) can regulate the activated phenotype of CLL cells and/or fitness of the surface-immunoglobulin (sIg) B cell receptor (BCR) complex expressed by CLL cells, thereby accounting for the differential leukemia-cell expression of these miRNAs in different CLL prognostic subgroups." target gene hsa-mir-19a "Leukemia, Lymphocytic, Chronic, B-Cell" 23597135 "Here we review studies that provide evidence suggesting that certain miRNAs (e.g. miR-155, miR-17-92, miR-181, miR-29) can regulate the activated phenotype of CLL cells and/or fitness of the surface-immunoglobulin (sIg) B cell receptor (BCR) complex expressed by CLL cells, thereby accounting for the differential leukemia-cell expression of these miRNAs in different CLL prognostic subgroups." target gene hsa-mir-19b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 23597135 "Here we review studies that provide evidence suggesting that certain miRNAs (e.g. miR-155, miR-17-92, miR-181, miR-29) can regulate the activated phenotype of CLL cells and/or fitness of the surface-immunoglobulin (sIg) B cell receptor (BCR) complex expressed by CLL cells, thereby accounting for the differential leukemia-cell expression of these miRNAs in different CLL prognostic subgroups." target gene hsa-mir-20a "Leukemia, Lymphocytic, Chronic, B-Cell" 23597135 "Here we review studies that provide evidence suggesting that certain miRNAs (e.g. miR-155, miR-17-92, miR-181, miR-29) can regulate the activated phenotype of CLL cells and/or fitness of the surface-immunoglobulin (sIg) B cell receptor (BCR) complex expressed by CLL cells, thereby accounting for the differential leukemia-cell expression of these miRNAs in different CLL prognostic subgroups." target gene hsa-mir-29 "Leukemia, Lymphocytic, Chronic, B-Cell" 23597135 "Here we review studies that provide evidence suggesting that certain miRNAs (e.g. miR-155, miR-17-92, miR-181, miR-29) can regulate the activated phenotype of CLL cells and/or fitness of the surface-immunoglobulin (sIg) B cell receptor (BCR) complex expressed by CLL cells, thereby accounting for the differential leukemia-cell expression of these miRNAs in different CLL prognostic subgroups." target gene hsa-mir-92-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 23597135 "Here we review studies that provide evidence suggesting that certain miRNAs (e.g. miR-155, miR-17-92, miR-181, miR-29) can regulate the activated phenotype of CLL cells and/or fitness of the surface-immunoglobulin (sIg) B cell receptor (BCR) complex expressed by CLL cells, thereby accounting for the differential leukemia-cell expression of these miRNAs in different CLL prognostic subgroups." target gene hsa-mir-19a Gastrointestinal Neoplasms 23603256 MicroRNA-19a/b regulates multidrug resistance in human gastric cancer cells by targeting PTEN. target gene hsa-mir-19b Gastrointestinal Neoplasms 23603256 MicroRNA-19a/b regulates multidrug resistance in human gastric cancer cells by targeting PTEN. target gene hsa-mir-150 Leukemia 23604034 "In conclusion, we demonstrate that miR-150 is a potent leukemic tumor suppressor that regulates multiple oncogenes." target gene hsa-mir-101 Bladder Neoplasms 23618864 MicroRNA-101 suppresses motility of bladder cancer cells by targeting c-Met. target gene hsa-mir-21 Cholangiocarcinoma 23621247 MicroRNA-21 regulates the invasion and metastasis in cholangiocarcinoma and may be a potential biomarker for cancer prognosis. target gene hsa-mir-19a Gastrointestinal Neoplasms 23621248 miR-19a promotes cell growth and tumorigenesis through targeting SOCS1 in gastric cancer. target gene hsa-mir-145 "Carcinoma, Hepatocellular" 23621665 miR-145 suppresses cell invasion in hepatocellular carcinoma cells: miR-145 targets ADAM17. target gene hsa-mir-135b Breast Neoplasms 23623609 miR-135b coordinates progression of ErbB2-driven mammary carcinomas through suppression of MID1 and MTCH2. target gene hsa-mir-124 Glioblastoma 23624869 Downregulation of miR-124 promotes the growth and invasiveness of glioblastoma cells involving upregulation of PPP1R13L. target gene hsa-mir-124 Glioblastoma 23636127 miR-124 inhibits STAT3 signaling to enhance T cell-mediated immune clearance of glioma. target gene hsa-mir-205 Melanoma 23638671 Our data suggest that miR-203 is a new prognostic factor in canine oral MMs and that miR-205 functions as a tumour suppressor by targeting erbb3 in both canine and human MM cells. target gene hsa-mir-143 "Adenocarcinoma, Pancreatic Ductal" 23661430 "SEL1L mRNA expression levels were found to correlate inversely with the expression of hsa-mir-143, hsa-mir-155, and hsa-mir-223 (P?A mutation in the GFPT1 gene leads to illegitimate binding of microRNA resulting in reduced protein expression. We confirm that c.*22C>A is a causative mutation and suggest that formation of microRNA target sites might be a relevant pathomechanism in Mendelian disorders. Variants in the 3'-UTRs should be considered in genetic diagnostic procedures. target gene hsa-mir-940 "Adenocarcinoma, Pancreatic Ductal" 25766528 Low level of miR-940 and high level of MyD88 in PDAC promoted PDAC cells growth which might be related to the low survival rate of PDAC patients.MiR-940 exerted its effect by targeting MyD88. target gene hsa-mir-122 Hepatitis B Virus Infection 25766860 Down-regulation of suppressor of cytokine signaling 3 by miR-122 enhances interferon-mediated suppression of hepatitis B virus. target gene hsa-mir-21 "Carcinoma, Cervical" 25769949 miR-21 modulates resistance of HR-HPV positive cervical cancer cells to radiation through targeting LATS1. target gene hsa-mir-199a Colorectal Carcinoma 25772759 FZD6 expression is negatively regulated by miR-199a-5p in human colorectal cancer. target gene hsa-mir-155 Chronic Hepatitis C 25772938 MicroRNA-155 regulates interferon-¦Ã production in natural killer cells via Tim-3 signalling in chronic hepatitis C virus infection. target gene hsa-mir-191 Osteosarcoma 25773391 MicroRNA-191 promotes osteosarcoma cells proliferation by targeting checkpoint kinase 2. target gene hsa-mir-196a Gastric Neoplasms 25773825 "Overexpression of mir-196a-5p is associated with lymph node metastasis and clinical stage, and enriched KEGG pathway analyses showed that targeted genes regulated by mir-196a-5p may contribute to tumorgenesis,suggesting roles as an oncogenic miRNA biomarker in gastric cancer." target gene hsa-mir-155 Systemic Lupus Erythematosus 25775145 "The results of the present study demonstrated for the first time that there is a differential expression and inverse correlation between the levels the miR-155, miR-17, and miR-181b and target molecules, AID and IFN-¦Á mRNAs, in PBMCs of untreated SLE patients. These alterations may contribute to the pathogenesis of SLE." target gene hsa-mir-17 Systemic Lupus Erythematosus 25775145 "The results of the present study demonstrated for the first time that there is a differential expression and inverse correlation between the levels the miR-155, miR-17, and miR-181b and target molecules, AID and IFN-¦Á mRNAs, in PBMCs of untreated SLE patients. These alterations may contribute to the pathogenesis of SLE." target gene hsa-mir-181b Systemic Lupus Erythematosus 25775145 "The results of the present study demonstrated for the first time that there is a differential expression and inverse correlation between the levels the miR-155, miR-17, and miR-181b and target molecules, AID and IFN-¦Á mRNAs, in PBMCs of untreated SLE patients. These alterations may contribute to the pathogenesis of SLE." target gene hsa-mir-215 Colorectal Carcinoma 25775580 The CDX1-microRNA-215 axis regulates colorectal cancer stem cell differentiation. target gene hsa-mir-377 "Carcinoma, Renal Cell, Clear-Cell" 25776481 miR-377 functions as a tumor suppressor in human clear cell renal cell carcinoma by targeting ETS1. target gene hsa-mir-325 "Carcinoma, Lung, Non-Small-Cell" 25776482 Expression of MicroRNA-325-3p and its potential functions by targeting HMGB1 in non-small cell lung cancer. target gene hsa-mir-183 Pancreatic Neoplasms 25776494 "miR-183 induces cell proliferation, migration, and invasion by regulating PDCD4 expression in the SW1990 pancreatic cancer cell line." target gene hsa-mir-411 "Carcinoma, Hepatocellular" 25776495 miR-411 regulated ITCH expression and promoted cell proliferation in human hepatocellular carcinoma cells. target gene hsa-mir-522 Glioblastoma 25776496 MiR-522 contributes to cell proliferation of human glioblastoma cells by suppressing PHLPP1 expression. target gene hsa-mir-423 Chronic Heart Failure 25776937 the results of the present study indicated that miR-423-5p was involved in CHF via the direct targeting of OGT and the induction of apoptosis in cardiomyocytes. target gene hsa-mir-27a Glioma 25777779 Emerging role of microRNA-27a in human malignant glioma cell survival via targeting of prohibitin. target gene hsa-mir-128 Glioma 25781272 Proteomic screening and identification of microRNA-128 targets in glioma cells. target gene hsa-mir-224 Meningioma 25783051 MicroRNA-224 targets ERG2 and contributes to malignant progressions of meningioma. target gene hsa-mir-15b Breast Neoplasms 25783158 EGF induces microRNAs that target suppressors of cell migration: miR-15b targets MTSS1 in breast cancer. target gene hsa-mir-34a Breast Neoplasms 25783790 MicroRNA-34a suppresses the breast cancer stem cell-like characteristics by downregulating Notch1 pathway. target gene hsa-mir-191 Colorectal Carcinoma 25784653 miR-191 promotes tumorigenesis of human colorectal cancer through targeting C/EBP¦Â. target gene hsa-mir-17 Atherosclerosis 25785043 miR-93 and miR-17 repress ABCA1 expression through directly targeting 3'UTR. target gene hsa-mir-29a "Carcinoma, Nasopharyngeal" 25786138 miR-29a/b enhances cell migration and invasion in nasopharyngeal carcinoma progression by regulating SPARC and COL3A1 gene expression. target gene hsa-mir-29b "Carcinoma, Nasopharyngeal" 25786138 miR-29a/b enhances cell migration and invasion in nasopharyngeal carcinoma progression by regulating SPARC and COL3A1 gene expression. target gene hsa-mir-34a Leukemia 25788289 MiR-34a regulates blood-tumor barrier function by targeting protein kinase C¦Å. target gene hsa-mir-200c Cardiovascular Diseases [unspecific] 25791170 These results demonstrate that induction of a miR-200c-SUMOylated KLF4 feedback loop is a significant aspect of the PDGF-BB proliferative response in VSMCs and that targeting Ubc9 represents a novel approach for the prevention of restenosis. target gene hsa-mir-153 Osteosarcoma 25793604 MicroRNA-153 inhibits osteosarcoma cells proliferation and invasion by targeting TGF-¦Â2. target gene hsa-mir-153 Breast Neoplasms 25794773 MiR-153 inhibits epithelial-mesenchymal transition by targeting metadherin in human breast cancer. target gene hsa-mir-204 Prostate Neoplasms 25797256 A dual yet opposite growth-regulating function of miR-204 and its target XRN1 in prostate adenocarcinoma cells and neuroendocrine-like prostate cancer cells. target gene hsa-mir-31 Liver Neoplasms 25797269 MicroRNA-31 functions as a tumor suppressor by regulating cell cycle and epithelial-mesenchymal transition regulatory proteins in liver cancer. target gene hsa-mir-182 Lung Neoplasms 25798833 The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers. target gene hsa-mir-183 Lung Neoplasms 25798833 The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers. target gene hsa-mir-200 Lung Neoplasms 25798833 The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers. target gene hsa-mir-96 Lung Neoplasms 25798833 The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers. target gene hsa-mir-30c Colorectal Carcinoma 25799050 Role of microRNA-30c targeting ADAM19 in colorectal cancer. target gene hsa-mir-194 "Adenocarcinoma, Gastric" 25800782 "We showed evidence that HNF4γ (upregulated in intestinal metaplasia) is targeted by miR-30 and that miR-194 targets a known co-regulator of HNF4 activity, NR2F2 (downregulated in intestinal metaplasia)." target gene hsa-mir-30a "Adenocarcinoma, Gastric" 25800782 "We showed evidence that HNF4γ (upregulated in intestinal metaplasia) is targeted by miR-30 and that miR-194 targets a known co-regulator of HNF4 activity, NR2F2 (downregulated in intestinal metaplasia)." target gene hsa-mir-26a Atherosclerosis 25801675 MicroRNA-26a prevents endothelial cell apoptosis by directly targeting TRPC6 in the setting of atherosclerosis. target gene hsa-mir-152 Diabetic Retinopathy 25802486 "We have demonstrated that miR-152 interacting with PRR regulates downstream VEGF, VRGFR-2, and TGF¦Â1 expressions in hRECs in HG conditions. These studies suggest miR-152 and PRR may play a role in the pathogenesis of diabetic retinopathy (DR)." target gene hsa-mir-21 Cholangiocarcinoma 25803229 MiR-21 promotes intrahepatic cholangiocarcinoma proliferation and growth in vitro and in vivo by targeting PTPN14 and PTEN. target gene hsa-mir-146a Hepatitis B Virus Infection 25805734 Upregulation of microRNA-146a by hepatitis B virus X protein contributes to hepatitis development by downregulating complement factor H. target gene hsa-mir-28 Ischemic Diseases [unspecific] 25807426 These findings suggest that miR-28 promotes myocardial ischemia through the inhibition of ALDH2 expression in mus. miRNAs is as a probable index in identification of myocardial ischemia after acute myocardial infarction. target gene hsa-mir-106b Pancreatic Neoplasms 25807437 Our findings may provide new insights into the knowledge of molecular mechanisms of pancreatic cancer and development of novel targeting therapies. target gene hsa-mir-125a Pancreatic Neoplasms 25807437 Our findings may provide new insights into the knowledge of molecular mechanisms of pancreatic cancer and development of novel targeting therapies. target gene hsa-mir-153 Pancreatic Neoplasms 25807437 Our findings may provide new insights into the knowledge of molecular mechanisms of pancreatic cancer and development of novel targeting therapies. target gene hsa-mir-181c Pancreatic Neoplasms 25807437 Our findings may provide new insights into the knowledge of molecular mechanisms of pancreatic cancer and development of novel targeting therapies. target gene hsa-mir-101 "Carcinoma, Hepatocellular" 25808945 Our results demonstrate that miR-101 regulates HCC cell phenotype by upregulating the epithelial marker genes and suppressing the mesenchymal ones. target gene hsa-mir-221 Inflammation 25810396 "Moreover, downregulation of KIT expression by miRNA-221 overexpression or the proteasome inhibitor bortezomib also reduced 3BP2 and MITF expression." target gene hsa-mir-134 "Carcinoma, Renal Cell" 25811077 miR-134 functions as a tumor suppressor in cell proliferation and epithelial-to-mesenchymal Transition by targeting KRAS in renal cell carcinoma cells. target gene hsa-mir-155 Stroke 25811992 miR-155 mediates inflammatory responses in ischemic cerebral tissue by modulating TLR4/MyD88 and SOCS1 expression target gene hsa-mir-218 Cardiac Myxoma 25812649 miR-218 suppresses cardiac myxoma proliferation by targeting myocyte enhancer factor 2D. target gene hsa-mir-200a "Carcinoma, Renal Cell" 25813153 Tumor suppressive microRNA-200a inhibits renal cell carcinoma development by directly targeting TGFB2. target gene hsa-mir-141 Breast Neoplasms 25813250 miR-141 confers docetaxel chemoresistance of breast cancer cells via regulation of EIF4E expression. target gene hsa-mir-7 Parkinson Disease 25814668 "microRNA-7, by down-regulating RelA,augments Glut3 expression, promotes glycolysis, and subsequently prevents MPP(+)-induced cell death. This protective effect of microRNA-7 could be exploited to correct the defects in oxidative phosphorylation in Parkinson disease." target gene hsa-mir-200b "Diabetes Mellitus, Type 2" 25814674 This study reports that (1) inflammation underlying nonhealing wounds in patients with type 2 diabetes mellitus influences plasma miRNA concentrations and (2) miR-191 modulates cellular migration and angiogenesis via paracrine regulation of zonula occludens-1 to delay the tissue repair process. target gene hsa-mir-191 "Carcinoma, Hepatocellular, HBV-Related" 25814782 "These findings highlight the importance of validating reference genes before quantifying target miRNAs.Furthermore, our findings will improve studies that monitor hepatitis progression and will aid in the discovery of noninvasive biomarkers to diagnose early stage HCC." target gene hsa-mir-221 "Carcinoma, Hepatocellular, HBV-Related" 25814782 "These findings highlight the importance of validating reference genes before quantifying target miRNAs.Furthermore, our findings will improve studies that monitor hepatitis progression and will aid in the discovery of noninvasive biomarkers to diagnose early stage HCC." target gene hsa-mir-26a "Carcinoma, Hepatocellular, HBV-Related" 25814782 "These findings highlight the importance of validating reference genes before quantifying target miRNAs.Furthermore, our findings will improve studies that monitor hepatitis progression and will aid in the discovery of noninvasive biomarkers to diagnose early stage HCC." target gene hsa-mir-146b Diabetes Mellitus 25815338 MicroRNA-146b-3p regulates retinal inflammation by suppressing adenosine deaminase-2 in diabetes. target gene hsa-mir-133a "Carcinoma, Gastric" 25815687 "MicroRNA-133a inhibits proliferation and invasion, and induces apoptosis in gastric carcinoma cells via targeting fascin actin-bundling protein 1." target gene hsa-mir-509 "Carcinoma, Renal Cell" 25815776 MicroRNA-509-3p inhibits cancer cell proliferation and migration by targeting the mitogen-activated protein kinase kinase kinase 8 oncogene in renal cell carcinoma. target gene hsa-mir-218 "Carcinoma, Hepatocellular" 25816091 MicroRNA-218 and microRNA-520a inhibit cell proliferation by downregulating E2F2 in hepatocellular carcinoma. target gene hsa-mir-520a "Carcinoma, Hepatocellular" 25816091 MicroRNA-218 and microRNA-520a inhibit cell proliferation by downregulating E2F2 in hepatocellular carcinoma. target gene hsa-let-7g Follicular Atresia 25817543 let-7g regulates the apoptosis of GCs in the pig ovary by targeting TGFBR1 and down-regulating the TGF-β signaling pathway. target gene hsa-mir-93 Intervertebral Disc Degeneration 25818544 "Taken together, we demonstrated that miR-93 contributed to abnormal NP cell type II collagen expression by targeting MMP3, involved in intervertebral disc degeneration." target gene hsa-mir-709 "Carcinoma, Hepatocellular" 25818666 These results suggest that miR-709 may positively regulate invasion and metastasis of HCC through targeting GPC5. target gene hsa-mir-449a Lung Neoplasms 25818739 "Our data indicate that miR-449a may function as a suppressor of lung cancer, and affects the expression of NEAT1 in lung cancer cells." target gene hsa-mir-200a Colorectal Carcinoma 25818799 "miR-200a plays a role in regulating the invasiveness and metastasis of CRC, and overexpression of miR-200a causes a significant reduction of cell proliferation and migration and promotes apoptosis and cell-cell adhesion in LoVo cells." target gene hsa-mir-490 Ovary Mixed Epithelial Carcinoma 25819031 MicroRNA-490-3P targets CDK1 and inhibits ovarian epithelial carcinoma tumorigenesis and progression. target gene hsa-mir-191 Endometriosis 25819812 "miR-191 can directly regulate TIMP3 expression, thereby affecting cell proliferation rate and invasion ability. The miR-191-TIMP3 axis might be critical in the malignant transformation of endometriosis to EAOC." target gene hsa-mir-494 "Carcinoma, Hepatocellular" 25820676 MicroRNA-494 is a master epigenetic regulator of multiple invasion-suppressor microRNAs by targeting ten eleven translocation 1 in invasive human hepatocellular carcinoma tumors. target gene hsa-mir-195 Osteosarcoma 25823925 MicroRNA profiling identifies MiR-195 suppresses osteosarcoma cell metastasis by targeting CCND1. target gene hsa-mir-155 "Squamous Cell Carcinoma, Esophageal" 25823933 "a novel pattern of differential miRNA-target expression was constructed, which with further investigation, may provide novel targets for diagnosing and understanding the mechanism of ESCC." target gene hsa-mir-202 "Squamous Cell Carcinoma, Esophageal" 25823933 "a novel pattern of differential miRNA-target expression was constructed, which with further investigation, may provide novel targets for diagnosing and understanding the mechanism of ESCC." target gene hsa-mir-107 "Adenocarcinoma, Gastric" 25824045 miR-107 and miR-25 simultaneously target LATS2 and regulate proliferation and invasion of gastric adenocarcinoma (GAC) cells. target gene hsa-mir-25 "Adenocarcinoma, Gastric" 25824045 miR-107 and miR-25 simultaneously target LATS2 and regulate proliferation and invasion of gastric adenocarcinoma (GAC) cells. target gene hsa-mir-520b "Carcinoma, Hepatocellular" 25824049 MiR-520b suppresses proliferation of hepatoma cells through targeting ten-eleven translocation 1 (TET1) mRNA. target gene hsa-mir-146b Inflammation 25824148 "Ang-1 disrupts TLR4 signalling, resulting in inhibition of LPS-induced inflammatory responses in endothelial cells. This inhibition occurs through selective targeting of IRAK1 and TRAF6 proteins by miR-146b-5p." target gene hsa-mir-454 Colorectal Carcinoma 25824771 MiR-454 prompts cell proliferation of human colorectal cancer cells by repressing CYLD expression. target gene hsa-mir-21 Multiple Myeloma 25825239 "Downregulation of Sprouty homolog 2 by microRNA-21 inhibits proliferation,metastasis and invasion, however promotes the apoptosis of multiple myeloma cells." target gene hsa-mir-34a Breast Neoplasms 25826085 Dysregulation of the miR-34a-SIRT1 axis inhibits breast cancer stemness. target gene hsa-mir-200b Colorectal Carcinoma 25826661 microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs. target gene hsa-mir-200c Colorectal Carcinoma 25826661 microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs. target gene hsa-mir-16 Breast Neoplasms 25830480 MicroRNA-16 modulates HuR regulation of cyclin E1 in breast cancer cells. target gene hsa-mir-142 Vascular Disease [unspecific] 25832008 this study demonstrates that miR-142-3p is a key regulator of the TGF¦Â-mediated contractile phenotype of VSMCs that acts through inhibiting cell migration through targeting DOCK6. target gene hsa-mir-193a "Carcinoma, Lung, Non-Small-Cell" 25833338 miR-193a-3p inhibited the metastasis of lung cancer cells by deregulating the expression of tumor-related proteins. These findings may improve the understanding of the molecular mechanisms underlying the metastatic-inhibitory effect of miR-193a-3p on lung cancer cells. target gene hsa-mir-429 "Adenocarcinoma, Pancreatic Ductal" 25833382 Low level of miR-429 and high level of TBK1 in PDAC promoted PDAC cells growth which might be related to the low survival rate of PDAC patients.MiR-429 play its role in PDAC by targeting TBK1. target gene hsa-mir-489 "Carcinoma, Lung, Non-Small-Cell" 25833694 Down-regulation of miR-489 contributes into NSCLC cell invasion through targeting SUZ12. target gene hsa-mir-197 Ovarian Neoplasms 25833695 MiR-197 induces Taxol resistance in human ovarian cancer cells by regulating NLK. target gene hsa-mir-139 Neoplasms [unspecific] 25833697 miR-139-5p suppresses cancer cell migration and invasion through targeting ZEB1 and ZEB2 in GBM. target gene hsa-mir-125a "Carcinoma, Lung, Small-Cell" 25833836 Chemotherapy-Regulated microRNA-125-HER2 Pathway as a Novel Therapeutic Target for Trastuzumab-Mediated Cellular Cytotoxicity in Small Cell Lung Cancer. target gene hsa-mir-195 "Carcinoma, Lung, Non-Small-Cell" 25840419 MiR-195 suppresses non-small cell lung cancer by targeting CHEK1. target gene hsa-mir-30 Glioma 25840690 miR-30 overexpression promotes glioma stem cells by regulating Jak/STAT3 signaling pathway. target gene hsa-mir-483 "Squamous Cell Carcinoma, Tongue" 25843291 miR-483-5p determines mitochondrial fission and cisplatin sensitivity in tongue squamous cell carcinoma by targeting FIS1. target gene hsa-mir-30d "Carcinoma, Lung, Non-Small-Cell" 25843294 MicroRNA-30d-5p inhibits tumour cell proliferation and motility by directly targeting CCNE2 in non-small cell lung cancer. target gene hsa-mir-21 "Carcinoma, Ovarian" 25845681 "Icariin regulates the proliferation and apoptosis of human ovarian cancer cells through microRNA-21 by targeting PTEN, RECK and Bcl-2." target gene hsa-mir-34c "Carcinoma, Endometrial" 25846116 "our study demonstrated that miR-34c plays a role of tumor suppressor in HEC-1-B cells, and E2F3 protein may be a target of miR-34c." target gene hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 25846727 "Our results demonstrate that p85¦Á expression is a determinant of chemosensitivity in PDAC. Additionally, we provide novel evidence that miR-21 can influence PI3K-AKT signaling via its direct regulation of p85¦Á. These data provide insight into potential mechanisms for the known relationship between increased p85¦Á expression and improved survival in PDAC." target gene hsa-mir-506 Gastric Neoplasms 25846731 MicroRNA-506 inhibits gastric cancer proliferation and invasion by directly targeting Yap1. target gene hsa-mir-4717 Anxiety Disorders 25847876 data indicate that MIR4717 regulates human RGS2 and contributes to the genetic risk towards anxiety-related traits. target gene hsa-mir-210 Hemoglobin Diseases 25849663 microRNA-210 and raptor are involved in mithramycin-mediated erythroid differentiation of K562 cells and participate to the fine-tuning and control of ¦Ã-globin gene expression in erythroid precursor cells. target gene hsa-mir-3127 "Carcinoma, Hepatocellular" 25849943 MicroRNA-3127 promotes cell proliferation and tumorigenicity in hepatocellular carcinoma by disrupting of PI3K/AKT negative regulation. target gene hsa-mir-107 "Carcinoma, Breast, Triple Negative" 25851994 MiR-107 down-regulates SIAH1 expression in human breast cancer cells and silencing of miR-107 inhibits tumor growth in a nude mouse model of triple-negative breast cancer. target gene hsa-mir-155 Melanoma 25853464 "microRNA-155, induced by interleukin-1?, represses the expression of microphthalmia-associated transcription factor (MITF-M) in melanoma cells." target gene hsa-mir-199a Glioma 25854175 MicroRNA-199a-3p suppresses glioma cell proliferation by regulating the AKT/mTOR signaling pathway. target gene hsa-mir-506 "Carcinoma, Nasopharyngeal" 25856555 MiR-506 suppresses tumor proliferation and invasion by targeting FOXQ1 in nasopharyngeal carcinoma. target gene hsa-mir-192 Hirschsprung Disease 25857602 Nidogen-1 is a common target of microRNAs MiR-192/215 in the pathogenesis of Hirschsprung's disease. target gene hsa-mir-215 Hirschsprung Disease 25857602 Nidogen-1 is a common target of microRNAs MiR-192/215 in the pathogenesis of Hirschsprung's disease. target gene hsa-mir-200c Ovarian Neoplasms 25860109 "This network included four separate types of interactions among miRNAs and genes. Simply analyzing each interaction component in isolation, such as the eQTL associations, the miRNA-target interactions or the protein-protein interactions, would create a much more limited network than the integrated one." target gene hsa-mir-22 Ovarian Neoplasms 25860109 "This network included four separate types of interactions among miRNAs and genes. Simply analyzing each interaction component in isolation, such as the eQTL associations, the miRNA-target interactions or the protein-protein interactions, would create a much more limited network than the integrated one." target gene hsa-mir-124 "Carcinoma, Renal Cell" 25861751 miR-124 represses FZD5 to attenuate P-glycoprotein-mediated chemo-resistance in renal cell carcinoma. target gene hsa-mir-492 "Carcinoma, Colon" 25862460 MiR-492 is functionally involved in Oxaliplatin resistance in colon cancer cells LS174T via its regulating the expression of CD147. target gene hsa-mir-7 "Carcinoma, Ovarian" 25862909 "There is a link between miR-7 expression and TP53 status and tumour grade in serous OC. Molecular mechanisms of these relationships need to be elucidated. Of the two postulated miR-7 target genes we examined, BCL2, but not EGFR, seems to be a possible miR-7 target in OC." target gene hsa-mir-375 Neuroblastoma 25864587 Targeting MYCN IRES in MYCN-amplified neuroblastoma with miR-375 inhibits tumor growth and sensitizes tumor cells to radiation. target gene hsa-mir-221 Inflammation 25865302 these results indicated that miR-221 targets AdipoR1 to regulate endothelial inflammatory response. target gene hsa-mir-186 Ovarian Neoplasms 25867064 miR-186 regulation of Twist1 and ovarian cancer sensitivity to cisplatin. target gene hsa-mir-133 "Adenocarcinoma, Lung" 25868726 Metastasis-associated lung adenocarcinoma transcript 1 (Malat1) regulates serum response factor through miR-133 as a competing endogenous RNA in myogenesis. target gene hsa-mir-33b Melanoma 25868853 "Cordycepin (3'-deoxyadenosine) suppressed HMGA2, Twist1 and ZEB1-dependent melanoma invasion and metastasis by targeting miR-33b." target gene hsa-mir-217 Gastric Neoplasms 25869101 microRNA-217 inhibits tumor progression and metastasis by downregulating EZH2 and predicts favorable prognosis in gastric cancer. target gene hsa-mir-155 Down Syndrome 25869329 These results suggest that regulation of TFAM by hsa-miR-155-5p impacts mitochondrial biogenesis in the diploid setting but not in the DS setting. target gene hsa-mir-124 Lung Neoplasms 25869366 "Novel potential regulatory miRNAs for RHOA (miR-9-1/-3, -34b/c, -129-2, -125b-1, -375, -1258) and NKIRAS1 (miR-34b/c, -129-2, -125b-1, -193a, -124a-1/-2/-3, -212, -132) genes in lung cancer were identified." target gene hsa-mir-1258 Lung Neoplasms 25869366 "Novel potential regulatory miRNAs for RHOA (miR-9-1/-3, -34b/c, -129-2, -125b-1, -375, -1258) and NKIRAS1 (miR-34b/c, -129-2, -125b-1, -193a, -124a-1/-2/-3, -212, -132) genes in lung cancer were identified." target gene hsa-mir-129 Lung Neoplasms 25869366 "Novel potential regulatory miRNAs for RHOA (miR-9-1/-3, -34b/c, -129-2, -125b-1, -375, -1258) and NKIRAS1 (miR-34b/c, -129-2, -125b-1, -193a, -124a-1/-2/-3, -212, -132) genes in lung cancer were identified." target gene hsa-mir-132 Lung Neoplasms 25869366 "Novel potential regulatory miRNAs for RHOA (miR-9-1/-3, -34b/c, -129-2, -125b-1, -375, -1258) and NKIRAS1 (miR-34b/c, -129-2, -125b-1, -193a, -124a-1/-2/-3, -212, -132) genes in lung cancer were identified." target gene hsa-mir-193a Lung Neoplasms 25869366 "Novel potential regulatory miRNAs for RHOA (miR-9-1/-3, -34b/c, -129-2, -125b-1, -375, -1258) and NKIRAS1 (miR-34b/c, -129-2, -125b-1, -193a, -124a-1/-2/-3, -212, -132) genes in lung cancer were identified." target gene hsa-mir-212 Lung Neoplasms 25869366 "Novel potential regulatory miRNAs for RHOA (miR-9-1/-3, -34b/c, -129-2, -125b-1, -375, -1258) and NKIRAS1 (miR-34b/c, -129-2, -125b-1, -193a, -124a-1/-2/-3, -212, -132) genes in lung cancer were identified." target gene hsa-mir-34b Lung Neoplasms 25869366 "Novel potential regulatory miRNAs for RHOA (miR-9-1/-3, -34b/c, -129-2, -125b-1, -375, -1258) and NKIRAS1 (miR-34b/c, -129-2, -125b-1, -193a, -124a-1/-2/-3, -212, -132) genes in lung cancer were identified." target gene hsa-mir-34c Lung Neoplasms 25869366 "Novel potential regulatory miRNAs for RHOA (miR-9-1/-3, -34b/c, -129-2, -125b-1, -375, -1258) and NKIRAS1 (miR-34b/c, -129-2, -125b-1, -193a, -124a-1/-2/-3, -212, -132) genes in lung cancer were identified." target gene hsa-mir-375 Lung Neoplasms 25869366 "Novel potential regulatory miRNAs for RHOA (miR-9-1/-3, -34b/c, -129-2, -125b-1, -375, -1258) and NKIRAS1 (miR-34b/c, -129-2, -125b-1, -193a, -124a-1/-2/-3, -212, -132) genes in lung cancer were identified." target gene hsa-mir-9 Lung Neoplasms 25869366 "Novel potential regulatory miRNAs for RHOA (miR-9-1/-3, -34b/c, -129-2, -125b-1, -375, -1258) and NKIRAS1 (miR-34b/c, -129-2, -125b-1, -193a, -124a-1/-2/-3, -212, -132) genes in lung cancer were identified." target gene hsa-mir-183 Graves Disease 25871842 Our study highlights the possibility that miRNA-target gene network may be involved in the pathogenesis of GD and could provide new insights into understanding the pathophysiological mechanisms of GD. target gene hsa-mir-197 Graves Disease 25871842 Our study highlights the possibility that miRNA-target gene network may be involved in the pathogenesis of GD and could provide new insights into understanding the pathophysiological mechanisms of GD. target gene hsa-mir-22 Graves Disease 25871842 Our study highlights the possibility that miRNA-target gene network may be involved in the pathogenesis of GD and could provide new insights into understanding the pathophysiological mechanisms of GD. target gene hsa-mir-660 Graves Disease 25871842 Our study highlights the possibility that miRNA-target gene network may be involved in the pathogenesis of GD and could provide new insights into understanding the pathophysiological mechanisms of GD. target gene hsa-mir-203 Oral Submucous Fibrosis 25872484 "Thus, we provide evidence to illustrate that miR-203 plays a role in the pathogenesis of OSF, which may be a target for OSF management." target gene hsa-mir-181b Retinoblastoma 25872572 Hypoxia-induced miR-181b enhances angiogenesis of retinoblastoma cells by targeting PDCD10 and GATA6. target gene hsa-mir-494 "Carcinoma, Colon" 25873402 MicroRNA-494 sensitizes colon cancer cells to fluorouracil through regulation of DPYD. target gene hsa-mir-15a "Carcinoma, Lung, Non-Small-Cell" 25874488 MicroRNA-15a induces cell apoptosis and inhibits metastasis by targeting BCL2L2 in non-small cell lung cancer. target gene hsa-mir-1 Gastric Neoplasms 25874496 MicroRNA-1 (miR-1) inhibits gastric cancer cell proliferation and migration by targeting MET. target gene hsa-mir-10b "Carcinoma, Laryngeal" 25875782 MicroRNA-10b Triggers the Epithelial-Mesenchymal Transition (EMT) of Laryngeal Carcinoma Hep-2 Cells by Directly Targeting the E-cadherin. target gene hsa-mir-200b Glioma 25877314 miR-200b may suppress cell invasion by targeting PROM1 in glioma. target gene hsa-mir-34a Bladder Neoplasms 25878394 miR-34a inhibits proliferation and invasion of bladder cancer cells by targeting orphan nuclear receptor HNF4G. target gene hsa-mir-33a Osteoarthritis 25880168 "Our findings suggest, for the first time to our knowledge, that miR-33a regulates cholesterol synthesis through the TGF-¦Â1/Akt/SREBP-2 pathway,as well as cholesterol efflux-related genes ABCA1 and ApoA1, in OA chondrocytes, pointing to its identification as a novel target for ameliorating the OA phenotype." target gene hsa-mir-372 "Carcinoma, Hepatocellular" 25880458 miR-372 may play an important role in hepatic carcinogenesis and may serve as a new target or method to detect and treat HCC in the future. target gene hsa-mir-7 Lung Neoplasms 25880778 KCNJ2/Kir2.1 modulates cell growth and drug resistance by regulating MRP1/ABCC1 expression and is simultaneously regulated by the Ras/MAPK pathway and miR-7. KCNJ2/Kir2.1 may be a prognostic predictor and a potentially novel target for interfering with chemoresistance in SCLC. target gene hsa-mir-223 Lung Neoplasms 25881295 Our study demonstrates for the first time that platelet-secreted miR-223 via P-MVs can promote lung cancer cell invasion via targeting tumor suppressor EPB41L3. target gene hsa-mir-221 Pancreatic Neoplasms 25883224 miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases. target gene hsa-mir-222 Pancreatic Neoplasms 25883224 miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases. target gene hsa-mir-200b Diabetes Mellitus 25884496 Polycomb repressive complex 2 regulates MiR-200b in retinal endothelial cells:potential relevance in diabetic retinopathy. target gene hsa-mir-132 Autism Spectrum Disorder 25885346 We found that through p-CREB/miR-132 signaling cascade is involved in MeCP2-mediated pain transduction. target gene hsa-mir-200 Breast Neoplasms 25886595 "The ADAM12-L 3'UTR is a direct target of miR-29 and miR-200 family members. Since the miR-29 and miR-200 families play important roles in breast cancer progression, these results may help explain the different prognostic and chemopredictive values of ADAM12-L and ADAM12-S in breast cancer." target gene hsa-mir-29 Breast Neoplasms 25886595 "The ADAM12-L 3'UTR is a direct target of miR-29 and miR-200 family members. Since the miR-29 and miR-200 families play important roles in breast cancer progression, these results may help explain the different prognostic and chemopredictive values of ADAM12-L and ADAM12-S in breast cancer." target gene hsa-mir-126 Obesity 25887648 We identified 23 active miRNA-TF-gene regulatory pathways that were significantly related to obesity-related inflammation. target gene hsa-mir-145 Obesity 25887648 We identified 23 active miRNA-TF-gene regulatory pathways that were significantly related to obesity-related inflammation. target gene hsa-mir-193b Obesity 25887648 We identified 23 active miRNA-TF-gene regulatory pathways that were significantly related to obesity-related inflammation. target gene hsa-mir-21 Obesity 25887648 We identified 23 active miRNA-TF-gene regulatory pathways that were significantly related to obesity-related inflammation. target gene hsa-mir-29b Obesity 25887648 We identified 23 active miRNA-TF-gene regulatory pathways that were significantly related to obesity-related inflammation. target gene hsa-mir-223 "Carcinoma, Gastric" 25888377 Our findings revealed the roles of miR-223/FBXW7 signaling in the DDP resistance of GC cells and targeting it will be a potential strategic approach for reversing the DDP resistance in human GC. target gene hsa-mir-29c "Carcinoma, Hepatocellular" 25888625 A suppressive role of ionizing radiation-responsive miR-29c in the development of liver carcinoma via targeting WIP1. target gene hsa-mir-211 "Carcinoma, Hepatocellular" 25888635 miR-211 suppresses hepatocellular carcinoma by downregulating SATB2. target gene hsa-mir-135a "Carcinoma, Bladder" 25888950 "Our study demonstrates that miR-135a promotes cell proliferation in bladder cancer by targeting PHLPP2 and FOXO1, and is performed as an onco-miR." target gene hsa-mir-31 Breast Neoplasms 25889182 These data provide strong evidence that GNA13 expression in breast cancer cells is regulated by post-transcriptional mechanisms involving miR-31.Additionally our data shows that miR-31 regulates breast cancer cell invasion partially via targeting GNA13 expression in breast cancer cells. Loss of miR-31 expression and increased GNA13 expression could be used as biomarkers of breast cancer progression. target gene hsa-mir-196b Neoplasms [unspecific] 25889892 we identified IGF2BP1 as a direct and functional target of miR-196b and showed that miR-196b overexpression reverses the chemoresistance induced by hypoxia. These results emphasize that the chemoresistance induced by hypoxia is a complex mechanism. target gene hsa-mir-203 Kidney Neoplasms 25890121 Our study suggested that miR-203 could be a potential prognostic marker and functions as a tumor suppressor in human renal cancer by post-transcriptionally targeting FGF2. target gene hsa-mir-21 Prostate Neoplasms 25890570 Androgen receptor and microRNA-21 axis downregulates transforming growth factor beta receptor II (TGFBR2) expression in prostate cancer. target gene hsa-mir-9 "Carcinoma, Nasopharyngeal" 25891118 "These data demonstrated that miR-9 did not modulate the sensitivity of the CNE2 cells to UV radiation through E-cadherin, but suggested that miR-9 regulated radiosensitivity through its effects on glutathione. These findings suggest that miR-9 may be a potential target for modulating the radiosensitivity of NPC cells." target gene hsa-mir-155 Inflammation 25892184 "miR-155-dependent regulation of mammalian sterile 20-like kinase 2 (MST2) coordinates inflammation, oxidative stress and proliferation in vascular smooth muscle cells." target gene hsa-mir-93 "Carcinoma, Nasopharyngeal" 25892549 MicroRNA-93 promotes cell growth and invasion in nasopharyngeal carcinoma by targeting disabled homolog-2. target gene hsa-mir-572 "Carcinoma, Ovarian" 25893382 Upregulation of miR-572 transcriptionally suppresses SOCS1 and p21 and contributes to human ovarian cancer progression. target gene hsa-mir-4717 Hepatitis B Virus Infection 25895129 microRNA-4717 differentially interacts with its polymorphic target in the PD1 3' untranslated region: A mechanism for regulating PD-1 expression and function in HBV-associated liver diseases. target gene hsa-mir-34a Ovarian Neoplasms 25895459 MiR-34a suppresses ovarian cancer proliferation and motility by targeting AXL. target gene hsa-mir-342 Obesity 25895816 "miR-342-3p is a powerful enhancer of the adipogenesis of human adipose-derived MSCs that acts by inhibiting CtBP2 and releasing the key adipogenic regulator C/EBP¦Á from CtBP2 binding, subsequently activating the expression of adipogenic transcription factors and markers." target gene hsa-mir-141 "Carcinoma, Hepatocellular" 25896253 "Our study showed that miR-141 plays a key role in 5-FU resistance by down-regulating Keap1 expression, thereby reactivating the Nrf2-dependent antioxidant pathway, which may serve as a potential target for overcoming 5-FU resistance in hepatocellular carcinoma cells." target gene hsa-mir-21 Cardiovascular Diseases [unspecific] 25898844 "In cardiac fibrosis related to Ang II, miR-21 is transcriptionally activated and targets PTEN/SMAD7 resulting in increased fibroblast survival. OPN KO animals are protected from miR-21 increase and fibrosis development due to impaired AP-1 activation and fibroblast activation." target gene hsa-mir-218 Breast Neoplasms 25900794 miR-218 targets survivin and regulates resistance to chemotherapeutics in breast cancer. target gene hsa-mir-320 Glioma 25901521 MicroRNA-320 inhibits cell proliferation in glioma by targeting E2F1. target gene hsa-mir-15b Glioma 25901555 Mangiferin regulates proliferation and apoptosis in glioma cells by induction of microRNA-15b and inhibition of MMP-9 expression. target gene hsa-mir-148a Glioblastoma 25903473 "miR-31 and miR-148a regulate glioma growth by maintaining tumor stem cells and their niche, and providing the tumor a way to activate angiogenesis even in a normoxic environment.This is the first study that demonstrates intratumoral uptake and growth-inhibiting effects of uncomplexed antagomirs in orthotopic glioma." target gene hsa-mir-31 Glioblastoma 25903473 "miR-31 and miR-148a regulate glioma growth by maintaining tumor stem cells and their niche, and providing the tumor a way to activate angiogenesis even in a normoxic environment.This is the first study that demonstrates intratumoral uptake and growth-inhibiting effects of uncomplexed antagomirs in orthotopic glioma." target gene hsa-mir-193b Pancreatic Neoplasms 25905463 Deregulation of the MiR-193b-KRAS Axis Contributes to Impaired Cell Growth in Pancreatic Cancer. target gene hsa-mir-135b Prostate Neoplasms 25907805 "MicroRNA-135b regulates ER¦Á, AR and HIF1AN and affects breast and prostate cancer cell growth." target gene hsa-mir-144 Neoplasms [unspecific] 25907866 MicroRNA-144 suppresses tumorigenesis and tumor progression of astrocytoma by targeting EZH2. target gene hsa-mir-218 "Carcinoma, Cervical" 25908215 MicroRNA-218 increases cellular sensitivity to Rapamycin via targeting Rictor in cervical cancer. target gene hsa-mir-200b "Carcinoma, Hepatocellular" 25909223 MiR-200b/200c/429 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis. target gene hsa-mir-200c "Carcinoma, Hepatocellular" 25909223 MiR-200b/200c/428 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis. target gene hsa-mir-429 "Carcinoma, Hepatocellular" 25909223 MiR-200b/200c/427 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis. target gene hsa-mir-21 "Lymphoma, B-Cell" 25909227 MicroRNA-21 plays an oncogenic role by targeting FOXO1 and activating the PI3K/AKT pathway in diffuse large B-cell lymphoma. target gene hsa-let-7c "Carcinoma, Hepatocellular" 25909324 MicroRNA let-7c Inhibits Cell Proliferation and Induces Cell Cycle Arrest by Targeting CDC25A in Human Hepatocellular Carcinoma. target gene hsa-mir-21 "Leukemia, Lymphocytic, Chronic, B-Cell" 25909590 IL-4 Up-Regulates MiR-21 and the MiRNAs Hosted in the CLCN5 Gene in Chronic Lymphocytic Leukemia. target gene hsa-mir-144 Osteosarcoma 25912304 MicroRNA-144 suppresses osteosarcoma growth and metastasis by targeting ROCK1 and ROCK2. target gene hsa-mir-129 "Carcinoma, Hepatocellular" 25912876 MicroRNA-129-5p inhibits hepatocellular carcinoma cell metastasis and invasion via targeting ETS1. target gene hsa-mir-3144 Human Papilloma Virus Infection 25913515 Two less common human microRNAs miR-875 and miR-3144 target a conserved site of E6 oncogene in most high-risk human papillomavirus subtypes. target gene hsa-mir-875 Human Papilloma Virus Infection 25913515 Two less common human microRNAs miR-875 and miR-3144 target a conserved site of E6 oncogene in most high-risk human papillomavirus subtypes. target gene hsa-mir-145 Colorectal Carcinoma 25913620 Tumor suppressor miR-145 reverses drug resistance by directly targeting DNA damage-related gene RAD18 in colorectal cancer. target gene hsa-mir-185 Hepatitis C Virus Infection 25914460 HCV core protein disturbs the cholesterol homeostasis in HepG2 cells via the SREBP2 pathway; miR-185-5p is involved in the regulation of SREBP2 by the core protein. target gene hsa-mir-451 Multiple Myeloma 25915427 MicroRNA-451 regulates stemness of side population cells via PI3K/Akt/mTOR signaling pathway in multiple myeloma. target gene hsa-mir-33b Breast Neoplasms 25919570 "MicroRNA-33b Inhibits Breast Cancer Metastasis by Targeting HMGA2, SALL4 and Twist1." target gene hsa-mir-18a Neoplasms [unspecific] 25923049 "this probe can be used for cell-specific intracellular miRNA sensing with a confocal microscope. Using miRNA-18a as a target model, the dynamic changes of its expression level inside living cells can be monitored with the proposed method. This method possesses promising applications in the study of miRNA related bioprocesses and biomedicine." target gene hsa-mir-144 Gastric Neoplasms 25927670 MicroRNA-144 inhibits the metastasis of gastric cancer by targeting MET expression. target gene hsa-mir-148b "Carcinoma, Lung, Non-Small-Cell" 25927928 miR-148b reverses cisplatin-resistance in non-small cell cancer cells via negatively regulating DNMT1 expression. target gene hsa-mir-145 "Carcinoma, Colon" 25928322 "Our current observations suggest that miR-21, miR-145, and their networks play critical roles in regulating CSCs growth and/or differentiation in the colon cancer and progression of chemo-resistance." target gene hsa-mir-21 "Carcinoma, Colon" 25928322 "Our current observations suggest that miR-21, miR-145, and their networks play critical roles in regulating CSCs growth and/or differentiation in the colon cancer and progression of chemo-resistance." target gene hsa-mir-124 "Carcinoma, Esophageal" 25928665 "Collectively, these data suggest that miR-124 functions as a tumor suppressor in esophageal cancer through, at least partially, targeting STAT3 signaling pathway." target gene hsa-mir-23a Colorectal Carcinoma 25929864 Elevated microRNA-23a Expression Enhances the Chemoresistance of Colorectal Cancer Cells with Microsatellite Instability to 5-Fluorouracil by Directly Targeting ABCF1. target gene hsa-mir-193a Inflammatory Bowel Diseases 25931122 "These findings suggest that miR-193a-3p regulation of PepT1 mediates the uptake of bacterial products and is a potent mechanism during the colonic inflammation process. Overall, we believe miR-193a-3p may be a potent regulator of colonic PepT1 for maintaining intestinal homeostasis." target gene hsa-mir-1291 Neoplasms [unspecific] 25934574 Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity. target gene hsa-mir-330 "Carcinoma, Lung, Non-Small-Cell" 25935837 miR-330-3p controls cell proliferation by targeting early growth response 2 in non-small-cell lung cancer. target gene hsa-mir-383 Glioma 25936342 "MicroRNA-383 expression regulates proliferation, migration, invasion, and apoptosis in human glioma cells." target gene hsa-mir-135b Glioblastoma 25936394 MicroRNA-135b exerts oncogenic activity in glioblastoma via the inhibition of glycerol kinase 5 expression. target gene hsa-mir-16 Spinal Cord Injuries 25936407 "A number of microRNAs (e.g. miR210, miR-487b and miR-16) were observed to target cholesterol metabolism-associated DGEs." target gene hsa-mir-19a Prostate Neoplasms 25936765 MicroRNA-19a regulates proliferation and apoptosis of castration-resistant prostate cancer cells by targeting BTG1. target gene hsa-mir-145 "Carcinoma, Ovarian" 25937243 Quercetin induces the apoptosis of human ovarian carcinoma cells by upregulating the expression of microRNA-145. target gene hsa-mir-137 Glioblastoma 25939439 MiR-137 inhibits proliferation and angiogenesis of human glioblastoma cells by targeting EZH2. target gene hsa-mir-137 Colorectal Carcinoma 25940441 Tumor suppressive microRNA-137 negatively regulates Musashi-1 and colorectal cancer progression. target gene hsa-mir-25 Gastric Neoplasms 25944166 "MicroRNA-25 promotes gastric cancer proliferation, invasion, and migration by directly targeting F-box and WD-40 Domain Protein 7, FBXW7." target gene hsa-mir-132 Ischemic Diseases [unspecific] 25945589 The miR-132/212 cluster promotes arteriogenesis by modulating Ras-MAPK signalling via direct targeting of its inhibitors Rasa1 and Spred1. target gene hsa-mir-212 Ischemic Diseases [unspecific] 25945589 The miR-132/212 cluster promotes arteriogenesis by modulating Ras-MAPK signalling via direct targeting of its inhibitors Rasa1 and Spred1. target gene hsa-mir-338 Gastric Neoplasms 25945841 MiR-338-3p inhibits epithelial-mesenchymal transition in gastric cancer cells by targeting ZEB2 and MACC1/Met/Akt signaling. target gene hsa-mir-2278 Leukemia 25953263 Revealing genome-wide mRNA and microRNA expression patterns in leukemic cells highlighted hsa-miR-2278 as a tumor suppressor for regain of chemotherapeutic imatinib response due to targeting STAT5A. target gene hsa-mir-429 "Carcinoma, Renal Cell" 25953723 These results revealed a tumor suppressive role for miR-429 in renal cell carcinoma through directly targeting BMI1 and E2F3. target gene hsa-mir-125b Liver Neoplasms 25953743 MicroRNA-125b attenuates epithelial-mesenchymal transitions and targets stem-like liver cancer cells through small mothers against decapentaplegic 2 and 4. target gene hsa-mir-34a "Squamous Cell Carcinoma, Esophageal" 25954903 miR-34a inhibits the migration and invasion of esophageal squamous cell carcinoma by targeting Yin Yang-1. target gene hsa-mir-153 Ovarian Neoplasms 25954928 MicroRNA-153 functions as a tumor suppressor by targeting SET7 and ZEB2 in ovarian cancer cells. target gene hsa-mir-1 "Carcinoma, Endometrial" 25955017 The tumor-suppressive microRNA-1/133a cluster targets PDE7A and inhibits cancer cell migration and invasion in endometrial cancer. target gene hsa-mir-133a "Carcinoma, Endometrial" 25955017 The tumor-suppressive microRNA-1/133a cluster targets PDE7A and inhibits cancer cell migration and invasion in endometrial cancer. target gene hsa-mir-494 Breast Neoplasms 25955111 miR-494 suppresses the progression of breast cancer in vitro by targeting CXCR4 through the Wnt/¦Â-catenin signaling pathway. target gene hsa-mir-139 Pancreatic Neoplasms 25955258 miR-139 and miR-200c regulate pancreatic cancer endothelial cell migration and angiogenesis. target gene hsa-mir-200c Pancreatic Neoplasms 25955258 miR-139 and miR-200c regulate pancreatic cancer endothelial cell migration and angiogenesis. target gene hsa-mir-18a Pregnancy Complications [unspecific] 25955393 "The results of the present study suggested that miR-18a expression suppression led to a decrease in JEG-3 cell invasion and an increase in JEG-3 cell apoptosis, by inducing ESR¦Á expression. The present study provides evidence for the involvement of miR-18a in the pathogenesis of pre-eclamptic pregnancies." target gene hsa-mir-29a Breast Neoplasms 25955714 MicroRNA-29a inhibits cell migration and invasion by targeting Roundabout 1 in breast cancer cells. target gene hsa-mir-216a "Squamous Cell Carcinoma, Oral" 25955794 MicroRNA-216a inhibits the growth and metastasis of oral squamous cell carcinoma by targeting eukaryotic translation initiation factor 4B. target gene hsa-mir-29 Ependymoma 25958202 microRNA network analysis identifies miR-29 cluster as key regulator of LAMA2 in ependymoma. target gene hsa-mir-25 Glioma 25960208 miR-25 promotes glioma cell proliferation by targeting CDKN1C. target gene hsa-mir-939 "Carcinoma, Ovarian" 25960217 MiR-939 promotes the proliferation of human ovarian cancer cells by repressing APC2 expression. target gene hsa-mir-20a Glioblastoma 25960225 miR-20a mediates temozolomide-resistance in glioblastoma cells via negatively regulating LRIG1 expression. target gene hsa-mir-146b "Carcinoma, Thyroid" 25960292 Inhibition of miR-146b expression increases radioiodine-sensitivity in poorly differential thyroid carcinoma via positively regulating NIS expression. target gene hsa-mir-1225 Breast Neoplasms 25961594 "our study demonstrates that HIPK2-kinase and the PLCXD1-phospholipase-C are novel targets of miR-193a-5p/miR-210-3p and miR-575/miR-1225-5p, respectively." target gene hsa-mir-125a Breast Neoplasms 25961594 "our study demonstrates that HIPK2-kinase and the PLCXD1-phospholipase-C are novel targets of miR-193a-5p/miR-210-3p and miR-575/miR-1225-5p, respectively." target gene hsa-mir-193 Breast Neoplasms 25961594 "our study demonstrates that HIPK2-kinase and the PLCXD1-phospholipase-C are novel targets of miR-193a-5p/miR-210-3p and miR-575/miR-1225-5p, respectively." target gene hsa-mir-210 Breast Neoplasms 25961594 "our study demonstrates that HIPK2-kinase and the PLCXD1-phospholipase-C are novel targets of miR-193a-5p/miR-210-3p and miR-575/miR-1225-5p, respectively." target gene hsa-mir-29a Breast Neoplasms 25961594 "our study demonstrates that HIPK2-kinase and the PLCXD1-phospholipase-C are novel targets of miR-193a-5p/miR-210-3p and miR-575/miR-1225-5p, respectively." target gene hsa-mir-575 Breast Neoplasms 25961594 "our study demonstrates that HIPK2-kinase and the PLCXD1-phospholipase-C are novel targets of miR-193a-5p/miR-210-3p and miR-575/miR-1225-5p, respectively." target gene hsa-mir-874 Breast Neoplasms 25961594 "our study demonstrates that HIPK2-kinase and the PLCXD1-phospholipase-C are novel targets of miR-193a-5p/miR-210-3p and miR-575/miR-1225-5p, respectively." target gene hsa-mir-622 Colorectal Carcinoma 25961730 Radiation-induced microRNA-622 causes radioresistance in colorectal cancer cells by down-regulating Rb. target gene hsa-mir-125a Leukemia 25961914 microRNA-125a (miR-125a) was identified as a miRNA that suppressed WT1 expression via binding to the WT1-3'UTR. target gene hsa-mir-125a Breast Neoplasms 25962054 MicroRNA-125a influences breast cancer stem cells by targeting leukemia inhibitory factor receptor which regulates the Hippo signaling pathway. target gene hsa-mir-1973 Lung Neoplasms 25962089 This may open the door for using epigenetic profile/miRNA expression of some cancer cells as resistance markers/targets to improve response of resistant cells to doxorubicin and for the use of combination doxorubicin/epigenetic modifiers to reduce doxorubicin toxicity. target gene hsa-mir-29b Lung Neoplasms 25962089 This may open the door for using epigenetic profile/miRNA expression of some cancer cells as resistance markers/targets to improve response of resistant cells to doxorubicin and for the use of combination doxorubicin/epigenetic modifiers to reduce doxorubicin toxicity. target gene hsa-mir-4286 Lung Neoplasms 25962089 This may open the door for using epigenetic profile/miRNA expression of some cancer cells as resistance markers/targets to improve response of resistant cells to doxorubicin and for the use of combination doxorubicin/epigenetic modifiers to reduce doxorubicin toxicity. target gene hsa-mir-494 Lung Neoplasms 25962089 This may open the door for using epigenetic profile/miRNA expression of some cancer cells as resistance markers/targets to improve response of resistant cells to doxorubicin and for the use of combination doxorubicin/epigenetic modifiers to reduce doxorubicin toxicity. target gene hsa-mir-128 "Carcinoma, Hepatocellular" 25962360 miR-128-3p suppresses hepatocellular carcinoma proliferation by regulating PIK3R1 and is correlated with the prognosis of HCC patients. target gene hsa-mir-9 "Carcinoma, Breast, Triple Negative" 25963903 Overexpression of Notch signaling via Notch1 intracellular domain in MDA-MB-231 cell line was suppressed by lentiviruses expressing miR-9. target gene hsa-mir-494 Pancreatic Neoplasms 25965392 "Ectopic expression of miR-494 inhibited the proliferation, invasion and chemoresistance of pancreatic cancer by regulating SIRT1 and c-Myc." target gene hsa-mir-361 Colorectal Carcinoma 25965817 MiR-361-5p inhibits colorectal and gastric cancer growth and metastasis by targeting staphylococcal nuclease domain containing-1. target gene hsa-mir-212 "Carcinoma, Hepatocellular" 25965836 MicroRNA-212 suppresses tumor growth of human hepatocellular carcinoma by targeting FOXA1. target gene hsa-mir-218 Bladder Neoplasms 25967457 "MicroRNA-218 inhibits bladder cancer cell proliferation, migration, and invasion by targeting BMI-1." target gene hsa-mir-125b Liver Diseases [unspecific] 25968989 "Our data suggest a mechanism for the marked changes in hepatic gene expression between the fetal and pediatric developmental periods, and support a role for these age-dependent miRNAs in regulating drug disposition." target gene hsa-mir-34a Liver Diseases [unspecific] 25968989 "Our data suggest a mechanism for the marked changes in hepatic gene expression between the fetal and pediatric developmental periods, and support a role for these age-dependent miRNAs in regulating drug disposition." target gene hsa-mir-448 "Carcinoma, Hepatocellular" 25969175 miR-448 may contribute to the progression of HCC via regulating ROCK2 expression. target gene hsa-mir-124 Prostate Neoplasms 25969668 overexpression of miR-124 by transient transfection of mimics led to a significant decrease in talin 1 levels. target gene hsa-mir-187 Prostate Neoplasms 25969992 MiR-187 Targets the Androgen-Regulated Gene ALDH1A3 in Prostate Cancer. target gene hsa-mir-33a "Carcinoma, Pancreatic" 25971209 MicroRNA-33a-mediated downregulation of Pim-3 kinase expression renders human pancreatic cancer cells sensitivity to gemcitabine. target gene hsa-mir-155 "Leukemia, Myeloid, Acute" 25971362 Pharmacological targeting of miR-155 via the NEDD8-activating enzyme inhibitor MLN4924 (Pevonedistat) in FLT3-ITD acute myeloid leukemia. target gene hsa-mir-148a Glioblastoma 25971746 "These findings uncover a plausible mechanism for NF-¦ÊB-sustained TGF-¦Â/Smad activation via miR-148a in glioblastoma, and may suggest a new target for clinical intervention in human cancer." target gene hsa-let-7g Gastric Neoplasms 25972194 Hsa-let-7g miRNA regulates the anti-tumor effects of gastric cancer cells under oxidative stress through the expression of DDR genes. target gene hsa-mir-205 Neoplasms [unspecific] 25973003 These results indicate that miR-205 might inhibitor the proliferation of A549 cells by regulating the expression of PTEN. target gene hsa-mir-145 Colorectal Carcinoma 25973017 MicroRNA-145 suppresses cell migration and invasion by targeting paxillin in human colorectal cancer cells. target gene hsa-mir-1247 Osteosarcoma 25973030 MiRNA profile of osteosarcoma with CD117 and stro-1 expression: miR-1247 functions as an onco-miRNA by targeting MAP3K9. target gene hsa-mir-877 "Carcinoma, Hepatocellular" 25973036 Up-regulation of miR-877 induced by paclitaxel inhibits hepatocellular carcinoma cell proliferation though targeting FOXM1. target gene hsa-mir-126 Liver Cirrhosis 25974152 "Further, miR-126 promoted TNF-a-induced TGF-¦Â1 and collagen I mRNA expression in LX-2 cells. miR-126 may play an important role in hepatic fibrosis by downregulating the expression of I¦ÊB¦Á partly through the NF-¦ÊB signaling pathway." target gene hsa-mir-141 Gastric Neoplasms 25975736 MicroRNA-141 inhibits migration of gastric cancer by targeting zinc finger E-box-binding homeobox 2. target gene hsa-mir-24 Osteomyelitis 25976273 "The Role of MicroRNA, miR-24, and Its Target CHI3L1 in Osteomyelitis Caused by Staphylococcus aureus." target gene hsa-mir-370 "Carcinoma, Lung, Non-Small-Cell" 25976502 MicroRNA-370 inhibits the progression of non-small cell lung cancer by downregulating oncogene TRAF4. target gene hsa-mir-142 "Carcinoma, Cervical" 25976503 MicroRNA-142-3p inhibits cell proliferation and invasion of cervical cancer cells by targeting FZD7. target gene hsa-mir-34 Wounds and Injuries [unspecific] 25978377 "our results provide compelling evidence supporting the existence of 106 novel miRNAs and the dynamic expression of miRNAs that extensively targets the TGF-¦Â pathway at different gestational ages in fetal KCs.MiRNAs showing altered expression at different gestational ages in fetal KCs may contribute to scarless wound healing in early- to mid-gestational fetal Keratinocytes (KCs), and thus may be new targets for potential scar prevention and reduction therapies." target gene hsa-mir-144 Bronchiolitis Obliterans Syndrome 25979625 "miR-144 is a critical regulator of the TGF-¦Â signaling cascade and is over-expressed in lungs with BOS. Therefore, miR-144 is a potential target toward preventing fibrosis leading to BOS after lung transplant." target gene hsa-mir-514a Melanoma 25980496 miR-514a regulates the tumour suppressor NF1 and modulates BRAFi sensitivity in melanoma. target gene hsa-mir-194 Inflammation 25984739 We conclude that miR-194 negatively regulates the TLR4 signal pathway which is activated by PA through directly negative TRAF6 expression. target gene hsa-mir-19a "Carcinoma, Hepatocellular" 25985117 A systematic investigation based on microRNA-mediated gene regulatory network reveals that dysregulation of microRNA-19a/Cyclin D1 axis confers an oncogenic potential and a worse prognosis in human hepatocellular carcinoma. target gene hsa-mir-200 "Diabetes Mellitus, Type 2" 25985365 The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes. target gene hsa-mir-125b Myeloma 25987254 Selective targeting of IRF4 by synthetic microRNA-125b-5p mimics induces anti-multiple myeloma activity in vitro and in vivo. target gene hsa-mir-197 Uterine Leiomyoma 25990270 Upregulation of miR-197 inhibits cell proliferation by directly targeting IGFBP5 in human uterine leiomyoma cells. target gene hsa-mir-184 "Carcinoma, Lung, Non-Small-Cell" 25990966 MiR-184 as a tumor suppressor miR inhibits cell proliferation and invasion capability via targeting CDC25A and c-Myc. Low miR-184 level may predict worse prognosis in NSCLC patients. target gene hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 25990966 MiR-184 as a tumor suppressor miR inhibits cell proliferation and invasion capability via targeting CDC25A and c-Myc. Low miR-184 level may predict worse prognosis in NSCLC patients. target gene hsa-mir-409 Colorectal Carcinoma 25991585 MicroRNA-409-3p suppresses colorectal cancer invasion and metastasis partly by targeting GAB1 expression. target gene hsa-mir-193a Bladder Neoplasms 25991669 The miR-193a-3p-regulated ING5 gene activates the DNA damage response pathway and inhibits multi-chemoresistance in bladder cancer. target gene hsa-mir-191 Neoplasms [unspecific] 25992613 MiR-191 Regulates Primary Human Fibroblast Proliferation and Directly Targets Multiple Oncogenes. target gene hsa-mir-100 Alzheimer Disease 25992776 "Referring to the Ingenuity database we could identify a set of AD associated genes that are targeted by these miRNAs. Highly predicted targets included genes involved in the regulation of tau and amyloid pathways in AD like MAPT, BACE1 and mTOR." target gene hsa-mir-103 Alzheimer Disease 25992776 "Referring to the Ingenuity database we could identify a set of AD associated genes that are targeted by these miRNAs. Highly predicted targets included genes involved in the regulation of tau and amyloid pathways in AD like MAPT, BACE1 and mTOR." target gene hsa-mir-21 Alzheimer Disease 25992776 "Referring to the Ingenuity database we could identify a set of AD associated genes that are targeted by these miRNAs. Highly predicted targets included genes involved in the regulation of tau and amyloid pathways in AD like MAPT, BACE1 and mTOR." target gene hsa-mir-219 Alzheimer Disease 25992776 "Referring to the Ingenuity database we could identify a set of AD associated genes that are targeted by these miRNAs. Highly predicted targets included genes involved in the regulation of tau and amyloid pathways in AD like MAPT, BACE1 and mTOR." target gene hsa-mir-296 Alzheimer Disease 25992776 "Referring to the Ingenuity database we could identify a set of AD associated genes that are targeted by these miRNAs. Highly predicted targets included genes involved in the regulation of tau and amyloid pathways in AD like MAPT, BACE1 and mTOR." target gene hsa-mir-3622b Alzheimer Disease 25992776 "Referring to the Ingenuity database we could identify a set of AD associated genes that are targeted by these miRNAs. Highly predicted targets included genes involved in the regulation of tau and amyloid pathways in AD like MAPT, BACE1 and mTOR." target gene hsa-mir-375 Alzheimer Disease 25992776 "Referring to the Ingenuity database we could identify a set of AD associated genes that are targeted by these miRNAs. Highly predicted targets included genes involved in the regulation of tau and amyloid pathways in AD like MAPT, BACE1 and mTOR." target gene hsa-mir-4467 Alzheimer Disease 25992776 "Referring to the Ingenuity database we could identify a set of AD associated genes that are targeted by these miRNAs. Highly predicted targets included genes involved in the regulation of tau and amyloid pathways in AD like MAPT, BACE1 and mTOR." target gene hsa-mir-505 Alzheimer Disease 25992776 "Referring to the Ingenuity database we could identify a set of AD associated genes that are targeted by these miRNAs. Highly predicted targets included genes involved in the regulation of tau and amyloid pathways in AD like MAPT, BACE1 and mTOR." target gene hsa-mir-708 Alzheimer Disease 25992776 "Referring to the Ingenuity database we could identify a set of AD associated genes that are targeted by these miRNAs. Highly predicted targets included genes involved in the regulation of tau and amyloid pathways in AD like MAPT, BACE1 and mTOR." target gene hsa-mir-766 Alzheimer Disease 25992776 "Referring to the Ingenuity database we could identify a set of AD associated genes that are targeted by these miRNAs. Highly predicted targets included genes involved in the regulation of tau and amyloid pathways in AD like MAPT, BACE1 and mTOR." target gene hsa-mir-15a "Aortic Aneurysm, Abdominal" 25993295 Our data emphasize the potential of miR-15a-3p and miR-30a-5p as biomarkers of AAA but also as triggers of ATLO evolution. Further investigations will be required to evaluate their targets in order to better understand AAA pathophysiology. target gene hsa-mir-30a "Aortic Aneurysm, Abdominal" 25993295 Our data emphasize the potential of miR-15a-3p and miR-30a-5p as biomarkers of AAA but also as triggers of ATLO evolution. Further investigations will be required to evaluate their targets in order to better understand AAA pathophysiology. target gene hsa-mir-489 "Aortic Aneurysm, Abdominal" 25993295 Our data emphasize the potential of miR-15a-3p and miR-30a-5p as biomarkers of AAA but also as triggers of ATLO evolution. Further investigations will be required to evaluate their targets in order to better understand AAA pathophysiology. target gene hsa-mir-1 Myocardial Infarction 25995211 These experiments revealed the role of inducible cAMP early repressor as a repressor of miR-1 and Ito target gene hsa-mir-1 Vascular Hypertrophy 25995211 These experiments revealed the role of inducible cAMP early repressor as a repressor of miR-1 and Ito target gene hsa-mir-23b Gastric Neoplasms 25996293 miR-23b-3p regulates the chemoresistance of gastric cancer cells by targeting ATG12 and HMGB2. target gene hsa-mir-21 Neoplasms [unspecific] 25997617 Our results suggest that miR-21 may regulate intestinal epithelial tight junction permeability through PTEN/PI3K/Akt signalling pathway. This promotes the feasibility of targeting miR-21 in the clinical to preserve the intestinal barrier. target gene hsa-mir-148b Liver Neoplasms 25997710 miRNA-148b suppresses hepatic cancer stem cell by targeting neuropilin-1. target gene hsa-mir-335 Neoplasms [unspecific] 25997740 miR-335 Targets SIAH2 and Confers Sensitivity to Anti-Cancer Drugs by Increasing the Expression of HDAC3. target gene hsa-mir-29a Gastric Neoplasms 25997819 MicroRNA-29a inhibits cell migration and invasion via targeting Roundabout homolog 1 in gastric cancer cells. target gene hsa-mir-377 Gastric Neoplasms 25998046 MicroRNA-377 predicts poor clinical outcome of gastric cancer and induces tumorigenesis by targeting multiple tumor-suppressor genes. target gene hsa-mir-125a "Carcinoma, Lung, Non-Small-Cell" 25998575 "miR-125a-3p targets MTA1 to suppress NSCLC cell proliferation, migration, and invasion." target gene hsa-mir-204 Osteosarcoma 25998694 "MicroRNA-204 inhibits proliferation, migration, invasion and epithelial-mesenchymal transition in osteosarcoma cells via targeting Sirtuin 1." target gene hsa-mir-155 "Colitis, Ulcerative" 25998827 MiR-155 modulates the inflammatory phenotype of intestinal myofibroblasts by targeting SOCS1 in ulcerative colitis. target gene hsa-mir-25 Lung Neoplasms 25998847 miR-25 targets the modulator of apoptosis 1 gene in lung cancer. target gene hsa-mir-218 "Squamous Cell Carcinoma, Esophageal" 25999024 MicroRNA-218 inhibits the proliferation and metastasis of esophageal squamous cell carcinoma cells by targeting BMI1. target gene hsa-mir-103 Adenovirus Infection 26000071 miR-103 Regulates Oxidative Stress by Targeting the BCL2/Adenovirus E1B 19kDa Interacting Protein 3 in HUVECs. target gene hsa-mir-182 "Fatty Liver, Non-Alcoholic" 26001595 E3 ubiquitin protein ligase (FBXW7) as potential targets of miR-182 target gene hsa-mir-526a Neoplasms [unspecific] 26002288 miR-526a regulates apoptotic cell growth in human carcinoma cells. target gene hsa-mir-582 "Carcinoma, Hepatocellular" 26002580 miR-582-5p inhibits proliferation of hepatocellular carcinoma by targeting CDK1 and AKT3. target gene hsa-mir-148a Ovarian Neoplasms 26004124 MicroRNA-148a inhibits the proliferation and promotes the paclitaxel-induced apoptosis of ovarian cancer cells by targeting PDIA3. target gene hsa-mir-148a Ovarian Neoplasms 26004261 MicroRNA-148a inhibits migration and invasion of ovarian cancer cells via targeting sphingosine-1-phosphate receptor 1. target gene hsa-mir-300 Osteosarcoma 26010572 Up-Regulation of MiR-300 Promotes Proliferation and Invasion of Osteosarcoma by Targeting BRD7. target gene hsa-mir-200b Breast Neoplasms 26011542 53BP1 suppresses epithelial-mesenchymal transition by downregulating ZEB1 through microRNA-200b/429 in breast cancer. target gene hsa-mir-429 Breast Neoplasms 26011542 53BP1 suppresses epithelial-mesenchymal transition by downregulating ZEB1 through microRNA-200b/429 in breast cancer. target gene hsa-mir-155 Vascular Disease [unspecific] 26012521 "knockdown of miR155 could modulate ROS production, NO generation, apoptosis and function of HBMECs via regulating diverse gene expression, such as caspase-3, ICAM-1 and EGFR/ERK/p38 MAPK and PI3K/Akt pathways." target gene hsa-mir-218 Glioblastoma 26012781 MiR-218 Inhibited Growth and Metabolism of Human Glioblastoma Cells by Directly Targeting E2F2. target gene hsa-mir-106b Vascular Disease [unspecific] 26013412 The knowledge of molecular targets that change during the senescence can ultimately contribute to a better understanding and prevention of age-related vascular diseases. target gene hsa-mir-16 Vascular Disease [unspecific] 26013412 The knowledge of molecular targets that change during the senescence can ultimately contribute to a better understanding and prevention of age-related vascular diseases. target gene hsa-mir-28 Vascular Disease [unspecific] 26013412 The knowledge of molecular targets that change during the senescence can ultimately contribute to a better understanding and prevention of age-related vascular diseases. target gene hsa-mir-376a Vascular Disease [unspecific] 26013412 The knowledge of molecular targets that change during the senescence can ultimately contribute to a better understanding and prevention of age-related vascular diseases. target gene hsa-mir-886 Vascular Disease [unspecific] 26013412 The knowledge of molecular targets that change during the senescence can ultimately contribute to a better understanding and prevention of age-related vascular diseases. target gene hsa-mir-133 Osteoporosis 26013661 "Estrogen deficiency is associated with miR-133 overexpression.MiR-133 can induce postmenopausal osteoporosis by weakening osteogenic differentiation of hMSCs, at least partly through repressing SLC39A1 expression." target gene hsa-mir-26b Obesity 26016996 Obesity-associated microRNA-26b regulates the proliferation of human preadipocytes via arrest of the G1/S transition. target gene hsa-mir-106a Kidney Neoplasms 26018509 miR-106a* inhibits the proliferation of renal carcinoma cells by targeting IRS-2. target gene hsa-mir-301a Pancreatic Neoplasms 26019136 MiR-301a-3p functions as a novel oncogene in PDAC and the oncogenic activity may involve its inhibition of the target gene SMAD4. target gene hsa-mir-495 Breast Neoplasms 26020378 Downregulated miR-495 [Corrected] Inhibits the G1-S Phase Transition by Targeting Bmi-1 in Breast Cancer. target gene hsa-mir-483 Prostate Neoplasms 26020509 "Based on our findings, we suggest that blood-based miRNA expression profiling can be used in the diagnosis and maybe even prognosis of the disease.In the future, miRNA profiling could possibly be used in targeted screening,together with Prostate Specific Antigene (PSA) testing, to identify men with an elevated PrCa risk." target gene hsa-mir-26a "Carcinoma, Hepatocellular" 26021873 miR-26a expression reduced M-CSF expression and recruitment of macrophages in hepatocellular carcinoma(HCC). target gene hsa-mir-139 "Carcinoma, Hepatocellular" 26022123 "miR-139-5p inhibits epithelial-mesenchymal transition, migration and invasion of hepatocellular carcinoma cells by targeting ZEB1 and ZEB2." target gene hsa-mir-101 Rheumatic Heart Diseases 26022377 The present study confirmed that miR-101 targets TLR2 3'UTR and represses TLR2 expression. This work also found an association between down-regulated miR-101 and rheumatic heart disease. target gene hsa-mir-30a Lung Neoplasms 26025408 MiR-30a suppresses non-small cell lung cancer progression through AKT signaling pathway by targeting IGF1R. target gene hsa-mir-200 "Carcinoma, Ovarian" 26025631 The miR-200 family differentially regulates sensitivity to paclitaxel and carboplatin in human ovarian carcinoma OVCAR-3 and MES-OV cells. target gene hsa-mir-150 "Leukemia-Lymphoma, Adult T-Cell" 26025667 STAT1: A Novel Target of miR-150 and miR-223 Is Involved in the Proliferation of HTLV-I-Transformed and ATL Cells. target gene hsa-mir-223 "Leukemia-Lymphoma, Adult T-Cell" 26025667 STAT1: A Novel Target of miR-150 and miR-223 Is Involved in the Proliferation of HTLV-I-Transformed and ATL Cells. target gene hsa-mir-199a "Squamous Cell Carcinoma, Skin or Unspecific" 26026896 "These results suggested that miR-199a-5p plays a role in pathogenesis of cSCC via inhibition of invasiveness through regulation of BCAM, FZD6 and DDR1 expression." target gene hsa-mir-199a Hepatitis C Virus Infection 26027911 Inhibition of microRNA-199a-5p reduces the replication of HCV via regulating the pro-survival pathway. target gene hsa-let-7 Glioma 26028311 MDM4 regulation by the let-7 miRNA family in the DNA damage response of glioma cells. target gene hsa-mir-101 Atherosclerosis 26033364 miR-101 promotes intracellular cholesterol retention under inflammatory conditions through suppressing ABCA1 expression and suggests that the miR-101-ABCA1 axis may play an intermediary role in the development of NAFLD and vascular atherosclerosis. target gene hsa-mir-491 "Carcinoma, Cervical" 26034994 MicroRNA-491-5p suppresses cervical cancer cell growth by targeting hTERT. target gene hsa-mir-126 "Adenocarcinoma, Lung" 26035298 "These DEGs, and DEG-related histone modifications, TFs and miRNAs may be important in the pathogenesis of lung adenocarcinoma. The present results may indicate directions for the next step in the study of the further elucidation and targeted prevention of lung adenocarcinoma." target gene hsa-mir-30c-2 "Adenocarcinoma, Lung" 26035298 "These DEGs, and DEG-related histone modifications, TFs and miRNAs may be important in the pathogenesis of lung adenocarcinoma. The present results may indicate directions for the next step in the study of the further elucidation and targeted prevention of lung adenocarcinoma." target gene hsa-mir-153 "Carcinoma, Hepatocellular" 26035427 miR-153 inhibits epithelial-to-mesenchymal transition in hepatocellular carcinoma by targeting Snail. target gene hsa-mir-34a Gastric Neoplasms 26035691 Depletion of histone deacetylase 1 inhibits metastatic abilities of gastric cancer cells by regulating the miR-34a/CD44 pathway. target gene hsa-mir-29a Pancreatic Neoplasms 26036346 Micro-RNAs miR-29a and miR-330-5p function as tumor suppressors by targeting the MUC1 mucin in pancreatic cancer cells. target gene hsa-mir-330 Pancreatic Neoplasms 26036346 Micro-RNAs miR-29a and miR-330-5p function as tumor suppressors by targeting the MUC1 mucin in pancreatic cancer cells. target gene hsa-mir-101 "Carcinoma, Breast, Triple Negative" 26036638 MicroRNA-101 inhibits cell progression and increases paclitaxel sensitivity by suppressing MCL-1 expression in human triple-negative breast cancer. target gene hsa-mir-375 Osteosarcoma 26036761 MicroRNA-375 functions as a tumor suppressor in osteosarcoma by targeting PIK3CA. target gene hsa-mir-18b "Leukemia, Promyelocytic, Acute" 26041820 PML/RAR¦Á-Regulated miR-181a/b Cluster Targets the Tumor Suppressor RASSF1A in Acute Promyelocytic Leukemia. target gene hsa-mir-522 "Carcinoma, Colon" 26043974 MicroRNA-522 reverses drug resistance of doxorubicin-induced HT29 colon cancer cell by targeting ABCB5. target gene hsa-mir-24 Breast Neoplasms 26044523 miRNA-24-3p promotes cell proliferation and inhibits apoptosis in human breast cancer by targeting p27Kip1. target gene hsa-mir-494 "Carcinoma, Hepatocellular" 26045065 "miR-494 promotes cell proliferation, migration and invasion, and increased sorafenib resistance in hepatocellular carcinoma by targeting PTEN." target gene hsa-mir-138 Psoriasis 26045321 MicroRNA-138 regulates the balance of Th1/Th2 via targeting RUNX3 in psoriasis. target gene hsa-mir-98 "Aortic Aneurysm, Abdominal" 26045772 "our data provide compelling evidence on the association between hypoxia and inflammation triggered by hypoxia and then mediated by MCP-1/miR-98/IL-6/p38 regulatory loop, which leads to hASMCs apoptosis via Stat1 activation to contribute to AAA formation and progression." target gene hsa-mir-570 "Carcinoma, Lung" 26045791 MicroRNA-570 promotes lung carcinoma proliferation through targeting tumor suppressor KLF9. target gene hsa-mir-503 "Carcinoma, Breast" 26047605 MiR-503 inhibited cell proliferation of human breast cancer cells by suppressing CCND1 expression. target gene hsa-let-7 "Carcinoma, Cervical" 26051842 "Overall, our study suggests that the microRNAs, miR-21 and let-7a function as clinically relevant integral components of STAT3 signaling and are responsible for maintaining activated state of STAT3 in HPV-infected cells during cervical carcinogenesis." target gene hsa-mir-206 "Carcinoma, Breast, Triple Negative" 26053033 "Consistent with increased levels of miR-206 in MaCSCs, the expression of both PDCD4 and CX43 was suppressed in these cells relative to control cells." target gene hsa-mir-106b Giant Cell Tumor of Bone 26053181 MicroRNA-106b inhibits osteoclastogenesis and osteolysis by targeting RANKL in giant cell tumor of bone. target gene hsa-mir-199a Liver Neoplasms 26054020 MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer. target gene hsa-mir-498 Ovarian Neoplasms 26054675 MiR-498 regulated FOXO3 expression and inhibited the proliferation of human ovarian cancer cells. target gene hsa-mir-485 "Carcinoma, Hepatocellular" 26054676 Involvement of miR-485-5p in hepatocellular carcinoma progression targeting EMMPRIN. target gene hsa-mir-126 Gastric Neoplasms 26054677 MicroRNA-126 inhibits cell proliferation in gastric cancer by targeting LAT-1. target gene hsa-mir-892a Colorectal Carcinoma 26054685 miR-892a regulated PPP2R2A expression and promoted cell proliferation of human colorectal cancer cells. target gene hsa-mir-217 Osteosarcoma 26054690 miR-217 targeting Wnt5a in osteosarcoma functions as a potential tumor suppressor. target gene hsa-mir-197 Colorectal Carcinoma 26055341 miR-197 mediates the response of colorectal cancer cells to 5-FU by regulating TYMS expression. target gene hsa-mir-99a Thrombocytopenia 26055579 "We believe that miR-99a regulates CTDSPL, which induces the G1/Stransition by increasing Cyclin expression and play a significant role in proliferation of CB-MKs." target gene hsa-mir-223 "Carcinoma, Nasopharyngeal" 26055874 "MiR-223 negatively regulates the growth and migration of NPC cells via reducing MAFB expression, and this finding provides a novel insight into understanding miR-223 regulation mechanism in nasopharyngeal carcinoma tumorigenesis." target gene hsa-mir-29a Atherosclerosis 26056009 "our study demonstrates that miR-29a inhibits QKI, which in turn results in upregulation of scavenger receptor A (SRA) and lipid uptake." target gene hsa-mir-144 Bladder Neoplasms 26057453 miR-144-5p functions as tumour suppressor in BC cells. CCNE1 and CCNE2 were directly regulated by miR-144-5p and might be good prognostic markers for survival of BC patients. target gene hsa-mir-429 "Carcinoma, Colon" 26058485 MicroRNA-429 inhibits the migration and invasion of colon cancer cells by targeting PAK6/cofilin signaling. target gene hsa-mir-19a "Carcinoma, Renal Cell" 26058752 Downregulation of miR-19a exhibits inhibitory effects on metastatic renal cell carcinoma by targeting PIK3CA and inactivating Notch signaling in vitro. target gene hsa-mir-16 "Adenocarcinoma, Lung" 26061016 Quercetin Decreases Claudin-2 Expression Mediated by Up-Regulation of microRNA miR-16 in Lung Adenocarcinoma A549 Cells. target gene hsa-mir-135b Colorectal Carcinoma 26061281 miR-135b Promotes Cancer Progression by Targeting Transforming Growth Factor Beta Receptor II (TGFBR2) in Colorectal Cancer. target gene hsa-mir-141 Prostate Neoplasms 26062412 miR-141-3p regulates the expression of androgen receptor by targeting its 3'UTR in prostate cancer LNCaP cells target gene hsa-mir-221 Bone Disease [unspecific] 26062554 Intercellular adhesion molecule-1 was upregulated by microRNA-221 in mesenchymal stem cells because microRNAs are key regulators of various biological functions via gene expression. target gene hsa-mir-92a Neoplasms [unspecific] 26062558 An In Vivo Method to Identify microRNA Targets Not Predicted by Computation Algorithms: p21 Targeting by miR-92a in Cancer. target gene hsa-mir-200b "Carcinoma, Breast, Triple Negative" 26062653 Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer. target gene hsa-mir-153 "Adenocarcinoma, Pancreatic Ductal" 26062664 MicroRNA-153 is a prognostic marker and inhibits cell migration and invasion by targeting SNAI1 in human pancreatic ductal adenocarcinoma. target gene hsa-mir-183 "Carcinoma, Thyroid, Papillary" 26063221 miR-183 regulates biological behavior in papillary thyroid carcinoma by targeting the programmed cell death 4. target gene hsa-mir-26a Prostate Neoplasms 26063484 MicroRNA-26a/b directly regulate La-related protein 1 and inhibit cancer cell invasion in prostate cancer. target gene hsa-mir-26b Prostate Neoplasms 26063484 MicroRNA-26a/b directly regulate La-related protein 1 and inhibit cancer cell invasion in prostate cancer. target gene hsa-mir-141 "Carcinoma, Prostate" 26065649 "The presence of the microRNA-141 target molecules activates the DNA molecular machine powered by the DNA fuel strands, leading to non-enzymatic target cyclic reuse of microRNA-141 and significantly amplified fluorescent signals for sensitive monitoring of microRNA-141 from low numbers of human prostate cancer cells." target gene hsa-mir-26b Lung Neoplasms 26068649 Down-regulation of microRNA-26b modulates non-small cell lung cancer cells chemoresistance and migration through the association of PTEN. target gene hsa-mir-145 "Carcinoma, Hepatocellular" 26068913 miR-145 regulates chemoresistance in hepatocellular carcinoma via epithelial mesenchymal transition. target gene hsa-mir-620 Neoplasms [unspecific] 26068950 miR-620 promotes tumor radioresistance by targeting 15-hydroxyprostaglandin dehydrogenase (HPGD). target gene hsa-let-7c Moyamoya Disease 26070522 "Increased expression of let-7c in MMD patients may contribute to MMD pathogenesis by targeting RNF213. Thus, let-7c may be a potential biomarker for the diagnosis of MMD." target gene hsa-mir-125a Melanoma 26071398 "we discovered that Lin28B, a well-characterized inhibitor of let-7 miRNA biogenesis, was a direct target of miR-125a-5p in melanoma." target gene hsa-mir-365 "Squamous Cell Carcinoma, Skin or Unspecific" 26072217 microRNA-365-targeted nuclear factor I/B transcriptionally represses cyclin-dependent kinase 6 and 4 to inhibit the progression of cutaneous squamous cell carcinoma. target gene hsa-mir-362 Neuroblastoma 26073258 miR-362-5p inhibits proliferation and migration of neuroblastoma cells by targeting phosphatidylinositol 3-kinase-C2¦Â. target gene hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 26077422 The role of miR-21 and miR-211 on MMP9 regulation in pancreatic ductal adenocarcinoma: cooperation in invasiveness behaviors target gene hsa-mir-211 "Adenocarcinoma, Pancreatic Ductal" 26077422 The role of miR-21 and miR-211 on MMP9 regulation in pancreatic ductal adenocarcinoma: cooperation in invasiveness behaviors target gene hsa-mir-34a Cholangiocarcinoma 26077733 microRNA-34a inhibits epithelial mesenchymal transition in human cholangiocarcinoma by targeting Smad4 through transforming growth factor-beta/Smad pathway. target gene hsa-mir-144 Leukemia 26078353 The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144. target gene hsa-mir-200b Neoplasms [unspecific] 26079153 Our results demonstrate that the p53 target miR-200b/200c/429 miRNAs are negative regulators of the CRKL oncogene. target gene hsa-mir-200c Neoplasms [unspecific] 26079153 Our results demonstrate that the p53 target miR-200b/200c/429 miRNAs are negative regulators of the CRKL oncogene. target gene hsa-mir-429 Neoplasms [unspecific] 26079153 Our results demonstrate that the p53 target miR-200b/200c/429 miRNAs are negative regulators of the CRKL oncogene. target gene hsa-mir-199a Osteosarcoma 26079799 CD44 is a direct target of miR-199a-3p and contributes to aggressive progression in osteosarcoma. target gene hsa-mir-139 Breast Neoplasms 26079880 MicroRNA-139 suppresses proliferation in luminal type breast cancer cells by targeting Topoisomerase II alpha. target gene hsa-mir-144 Osteosarcoma 26081423 MicroRNA-144 acts as a tumor suppressor by targeting Rho-associated coiled-coil containing protein kinase 1 in osteosarcoma cells. target gene hsa-mir-219 Glioblastoma 26081620 MicroRNA-219-5p exerts tumor suppressor function by targeting ROBO1 in glioblastoma. target gene hsa-mir-4649 "Carcinoma, Nasopharyngeal" 26081980 MicroRNA-4649-3p inhibits cell proliferation by targeting protein tyrosine phosphatase SHP-1 in nasopharyngeal carcinoma cells. target gene hsa-mir-21 Neoplasms [unspecific] 26082192 "we describe the ever-expanding role of miR-21 and its target genes in different cancers, and provide insight into how this oncogenic miRNA regulates cancer cell proliferation, migration, and apoptosis by suppressing the expression of tumor suppressors." target gene hsa-mir-340 Heart Failure 26084457 microRNA-340-5p Functions Downstream of Cardiotrophin-1 to Regulate Cardiac Eccentric Hypertrophy and Heart Failure via Target Gene Dystrophin. target gene hsa-mir-107 Glioma 26084601 Upregulation of miR-107 Inhibits Glioma Angiogenesis and VEGF Expression. target gene hsa-mir-570 "Carcinoma, Hepatocellular" 26084609 MiR-570 inhibited the cell proliferation and invasion through directly targeting B7-H1 in hepatocellular carcinoma. target gene hsa-mir-15b Myasthenia Gravis 26087886 "This study is the first to report the miR-15b-IL-15 axis can directly regulate IL15 expression, which helps to further explain the abnormal IL-15 expression in MG patients and the pathogenesis of MG." target gene hsa-mir-26b Rheumatoid Arthritis 26088648 "MiR-26b regulates ¦Â-catenin and CyclinD1 levels by inhibiting GSK-3¦Â expression, which in-turn alters the Wnt/GSK-3¦Â/¦Â-catenin pathway to lower RAFLS proliferation and elevate cell apoptosis and the secretion of TNF-¦Á,IL-1¦Â and IL-6 cytokines. Therefore, our results show that miR-26B plays a central role in inhibiting the inflammation associated with rheumatoid arthritis." target gene hsa-mir-9 Neoplasms [unspecific] 26091714 our findings have identified a critical role of miR-9 in regulating the differentiation and function of Myeloid-derived suppressor cells (MDSCs). target gene hsa-mir-206 Breast Neoplasms 26093295 "Overexpression of miR-206 suppresses glycolysis, proliferation and migration in breast cancer cells via PFKFB3 targeting." target gene hsa-mir-132 Liver Neoplasms 26096363 Hsa-miR-132 inhibits proliferation of hepatic carcinoma cells by targeting YAP. target gene hsa-mir-29a Neoplasms [unspecific] 26096783 Tumour-suppressive microRNA-29s directly regulate LOXL2 expression and inhibit cancer cell migration and invasion in renal cell carcinoma. target gene hsa-mir-29b Neoplasms [unspecific] 26096783 Tumour-suppressive microRNA-29s directly regulate LOXL2 expression and inhibit cancer cell migration and invasion in renal cell carcinoma. target gene hsa-mir-29c Neoplasms [unspecific] 26096783 Tumour-suppressive microRNA-29s directly regulate LOXL2 expression and inhibit cancer cell migration and invasion in renal cell carcinoma. target gene hsa-mir-34c "Carcinoma, Gastric" 26097561 PABPC1 exerts carcinogenesis in gastric carcinoma by targeting miR-34c. target gene hsa-mir-106a Lung Neoplasms 26097565 miR-106a promotes growth and metastasis of non-small cell lung cancer by targeting PTEN. target gene hsa-mir-139 Lung Neoplasms 26097570 Our results indicated that miR-139-5p acts as a tumor suppressor in non-small cell lung cancer (NSCLC) partially via down-regulating IGF1R expression. target gene hsa-mir-144 Liver Fibrosis 26097586 miR-144 regulates transforming growth factor-¦Â1 iduced hepatic stellate cell activation in human fibrotic liver. target gene hsa-mir-217 Gastric Neoplasms 26098560 The MicroRNA-217 Functions as a Potential Tumor Suppressor in Gastric Cancer by Targeting GPC5. target gene hsa-mir-21 Breast Neoplasms 26098771 The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer. target gene hsa-mir-34a Liver Diseases [unspecific] 26100857 miR-34a-HNF4¦Á pathway is activated under common conditions of metabolic stress and may have a role in the pathogenesis of Non-alcoholic fatty liver disease(NAFLD) and in regulating plasma lipoprotein metabolism. target gene hsa-mir-137 "Carcinoma, Gastric" 26102366 MicroRNA-137 Contributes to Dampened Tumorigenesis in Human Gastric Cancer by Targeting AKT2. target gene hsa-mir-34a Colorectal Carcinoma 26103003 MicroRNA-34a targets FMNL2 and E2F5 and suppresses the progression of colorectal cancer. target gene hsa-mir-370 Osteoarthritis 26103880 "miR-370 and miR-373 regulate the pathogenesis of osteoarthritis by modulating one-carbon metabolism via SHMT-2 and MECP-2, respectively." target gene hsa-mir-373 Osteoarthritis 26103880 "miR-370 and miR-373 regulate the pathogenesis of osteoarthritis by modulating one-carbon metabolism via SHMT-2 and MECP-2, respectively." target gene hsa-mir-448 Ovarian Neoplasms 26103953 "Our data indicate that miR-448 functions as a tumor suppressor in ovarian cancer, which exerts its activity by suppressing the expression of CXCL12." target gene hsa-mir-9 Melanoma 26104682 These results identify a novel YY1~miR-9~RYBP axis involved in melanoma tumorigenesis and reinforce the idea that regulatory circuitries involving miRNAs and TFs are prevalent mechanisms. target gene hsa-mir-9 Osteosarcoma 26107195 miR-9 Modulates Osteosarcoma Cell Growth by Targeting the GCIP Tumor Suppressor. target gene hsa-mir-34b Prostate Neoplasms 26107383 Deregulation of MiR-34b/Sox2 Predicts Prostate Cancer Progression. target gene hsa-mir-326 "Adenocarcinoma, Lung" 26111641 "Adam17, a Target of Mir-326, Promotes Emt-Induced Cells Invasion in Lung Adenocarcinoma." target gene hsa-mir-129 "Carcinoma, Hepatocellular" 26116538 miR-129 suppresses tumor cell growth and invasion by targeting PAK5 in hepatocellular carcinoma. target gene hsa-mir-15a Multiple Myeloma 26117022 "High expression of miR-15a can induce cell cycle arrest and apoptosis of MM cells, then inhibit their growth. The mechanisms may be related with the negative regulation of BMI-1 and BCL-2 genes in post-transcription level caused by miR-15a." target gene hsa-mir-1 Ovarian Neoplasms 26117268 "The mRNA level of HOTAIR and MAPK1 in ovarian SKOV3 decreased when transected with miR-1, miR-214-3p, or miR-330-5p compared to negative control (p<0.05)." target gene hsa-mir-19b Atherosclerosis 26117405 "Taken together, these results demonstrate that PGC-1¦Á plays a protective role against the vascular complications of atherosclerosis. Moreover, the posttranscriptional regulation of PGC-1¦Á by miR-19b/221/222 was unveiled,which provides a novel mechanism in which a panel of microRNAs can modulate endothelial cell apoptosis via the regulation mitochondrial function." target gene hsa-mir-221 Atherosclerosis 26117405 "Taken together, these results demonstrate that PGC-1¦Á plays a protective role against the vascular complications of atherosclerosis. Moreover, the posttranscriptional regulation of PGC-1¦Á by miR-19b/221/222 was unveiled,which provides a novel mechanism in which a panel of microRNAs can modulate endothelial cell apoptosis via the regulation mitochondrial function." target gene hsa-mir-222 Atherosclerosis 26117405 "Taken together, these results demonstrate that PGC-1¦Á plays a protective role against the vascular complications of atherosclerosis. Moreover, the posttranscriptional regulation of PGC-1¦Á by miR-19b/221/222 was unveiled,which provides a novel mechanism in which a panel of microRNAs can modulate endothelial cell apoptosis via the regulation mitochondrial function." target gene hsa-mir-193 Liver Fibrosis 26120970 These results suggest that miR-30 and miR-193 are members of a network of miRNAs modifying the TGF-¦Â-dependent regulation of extracellular matrix-related genes in HSCs in the manifestation and resolution of liver fibrosis. target gene hsa-mir-30 Liver Fibrosis 26120970 These results suggest that miR-30 and miR-193 are members of a network of miRNAs modifying the TGF-¦Â-dependent regulation of extracellular matrix-related genes in HSCs in the manifestation and resolution of liver fibrosis. target gene hsa-mir-153 Glioma 26124081 MicroRNA-153/Nrf-2/GPx1 pathway regulates radiosensitivity and stemness of glioma stem cells via reactive oxygen species. target gene hsa-mir-106b Prostate Neoplasms 26124181 miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progression. target gene hsa-mir-375 Prostate Neoplasms 26124181 miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progression. target gene hsa-mir-93 Prostate Neoplasms 26124181 miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progression. target gene hsa-mir-155 "Diabetes Mellitus, Type 2" 26125263 "In type 2 diabetes mellitus (T2DM) retinopathy, miR-155 may play an important role in the pathogenesis of T2DM retinopathy by regulating the Treg cells with TGF-¦Â." target gene hsa-mir-206 Breast Neoplasms 26125274 Our results suggest hsa-miR-206 may repress the tumor proliferation and invasion in breast cancer by targeting Cx43. target gene hsa-mir-9 "Carcinoma, Hepatocellular" 26125451 MicroRNA-9-3p was identified as the tumour-suppressor miR targetting TAZ expression in HCC cells. target gene hsa-mir-410 Pituitary Neoplasms 26125663 Downregulation of miR-410 targeting the cyclin B1 gene plays a role in pituitary gonadotroph tumors. target gene hsa-let-7 "Carcinoma, Nasopharyngeal" 26125802 The let-7 and miR-29 families may be related to the development of NPC by regulating the genes involved in cell cycle and ECM-receptor interaction. target gene hsa-mir-29 "Carcinoma, Nasopharyngeal" 26125802 The let-7 and miR-29 families may be related to the development of NPC by regulating the genes involved in cell cycle and ECM-receptor interaction. target gene hsa-mir-193b Prostate Neoplasms 26129688 Epigenetically altered miR-193b targets cyclin D1 in prostate cancer. target gene hsa-mir-205 "Carcinoma, Hepatocellular" 26129839 MicroRNA-205 regulates ubiquitin specific peptidase 7 protein expression in hepatocellular carcinoma cells. target gene hsa-mir-100 Breast Neoplasms 26130569 The role of miR-100 in regulating apoptosis of breast cancer cells. target gene hsa-mir-130a Gastric Neoplasms 26134263 "miR-130a acts as a potential diagnostic biomarker and promotes gastric cancer migration, invasion and proliferation by targeting RUNX3." target gene hsa-mir-133a "Carcinoma, Cervical" 26134491 miR-133a inhibits cervical cancer growth by targeting EGFR. target gene hsa-mir-99b "Carcinoma, Hepatocellular" 26134929 miR-99b promotes metastasis of hepatocellular carcinoma through inhibition of claudin 11 expression and may serve as a prognostic marker. target gene hsa-mir-7 Lung Neoplasms 26135959 MicroRNA-7 inhibits the malignant phenotypes of non-small cell lung cancer in vitro by targeting Pax6. target gene hsa-mir-203 Neuroblastoma 26136151 MicroRNA-203 inhibits the malignant progression of neuroblastoma by targeting Sam68. target gene hsa-mir-196 Neoplasms [unspecific] 26141604 The miR-196 miRNA gene family located within the Hox gene clusters hsa been shown to function during embryogenesis and to be aberrantly expressed in various malignancies target gene hsa-mir-21 Glioblastoma 26142886 Targeting strategies on miRNA-21 and PDCD4 for glioblastoma. target gene hsa-mir-216a Pancreatic Neoplasms 26149212 miR-216a may inhibit pancreatic tumor growth by targeting JAK2. target gene hsa-mir-410 Lung Neoplasms 26149213 MicroRNA-410 promotes cell proliferation by targeting BRD7 in non-small cell lung cancer. target gene hsa-mir-1283 Hypertension 26149214 inhibition of miR-1283 in HA-VSMCs enhanced the expression of Activating transcription factor 1 mRNA as well as the ROS levels. target gene hsa-mir-9 Bladder Neoplasms 26150338 miR-9 promotes cell proliferation and inhibits apoptosis by targeting LASS2 in bladder cancer. target gene hsa-mir-221 Epstein-Barr Virus Infection 26153983 Epstein-Barr Virus Proteins EBNA3A and EBNA3C Together Induce Expression of the Oncogenic MicroRNA Cluster miR-221/miR-222 and Ablate Expression of Its Target p57KIP2. ebv-miR-BART20-5p target gene hsa-mir-222 Epstein-Barr Virus Infection 26153983 Epstein-Barr Virus Proteins EBNA3A and EBNA3C Together Induce Expression of the Oncogenic MicroRNA Cluster miR-221/miR-222 and Ablate Expression of Its Target p57KIP2. ebv-miR-BART20-5p target gene hsa-mir-29b Glioblastoma 26155940 miR-29b attenuates tumorigenicity and stemness maintenance in human glioblastoma multiforme by directly targeting BCL2L2. target gene hsa-mir-133a "Carcinoma, Hepatocellular" 26156803 MicroRNA-133a functions as a tumor suppressor by targeting IGF-1R in hepatocellular carcinoma. target gene hsa-mir-612 Colorectal Carcinoma 26158514 miR-612 negatively regulates colorectal cancer growth and metastasis by targeting AKT2. target gene hsa-mir-101 "Carcinoma, Hepatocellular" 26158762 MiR-101 targets DUSP1 to regulate the TGF-¦Â secretion in sorafenib inhibits macrophage-induced growth of hepatocarcinoma. target gene hsa-mir-17 Melanoma 26158900 miR-17 regulates melanoma cell motility by inhibiting the translation of ETV1. target gene hsa-mir-155 Atherosclerosis 26159489 microRNA-155 works as a promoter in the atherosclerotic procession. Its mechanism may include enhancing inflammatory response in atherosclerosis by increasing STAT3 and NF-¦ÊB signaling via targeting SOCS1. target gene hsa-mir-1271 Gastric Neoplasms 26159618 "MiR-1271 Inhibits Cell Proliferation, Invasion and EMT in Gastric Cancer by Targeting FOXQ1." target gene hsa-mir-499 "Carcinoma, Esophageal" 26159783 MiR-499 Enhances the Cisplatin Sensitivity of Esophageal Carcinoma Cell Lines by Targeting DNA Polymerase ¦Â. target gene hsa-mir-141 Gastric Neoplasms 26160158 "These results were the first to demonstrate that H19 and miR-141 could compete with each other and affect their target genes in gastric cancer,which provide important clues for understanding the key roles of lncRNA-miRNA functional network in cancer." target gene hsa-mir-495 Medulloblastoma 26160158 Our results suggest that miR-495 may be a prognostic predictor in medulloblastoma and that Gfi1 is a potential functional target of miR-495. target gene hsa-mir-28 "Carcinoma, Hepatocellular" 26160280 Down-regulated miR-28-5p in human hepatocellular carcinoma correlated with tumor proliferation and migration by targeting insulin-like growth factor-1 (IGF-1). target gene hsa-mir-1275 "Carcinoma, Hepatocellular" 26160756 miR-1275: A single microRNA that targets the three IGF2-mRNA-binding proteins hindering tumor growth in hepatocellular carcinoma. target gene hsa-mir-503 "Carcinoma, Hepatocellular" 26163260 miR-503 suppresses metastasis of hepatocellular carcinoma cell by targeting PRMT1. target gene hsa-mir-137 Schizophrenia 26163462 Experimental validation of candidate schizophrenia gene CALN1 as a target for microRNA-137. target gene hsa-mir-99a "Carcinoma, Thyroid, Anaplastic" 26163618 MiR-99a Inhibits Cell Proliferation and Tumorigenesis through Targeting mTOR in Human Anaplastic Thyroid Cancer. target gene hsa-mir-27a Glioma 26164457 MiR-27a regulates Wnt/beta-catenin signaling through targeting SFRP1 in glioma. target gene hsa-mir-95 Glioma 26165303 "Downregulation of miR-95-3p inhibits proliferation, and invasion promoting apoptosis of glioma cells by targeting CELF2." target gene hsa-mir-20a Kidney Injury 26165754 MiR-20a-5p mediates hypoxia-induced autophagy by targeting ATG16L1 in ischemic kidney injury. target gene hsa-mir-20b Bladder Neoplasms 26166554 "MicroRNA-20b inhibits the proliferation, migration and invasion of bladder cancer EJ cells via the targeting of cell cycle regulation and Sp-1-mediated MMP-2 expression." target gene hsa-mir-134 Lung Neoplasms 26166818 MicroRNA-134 regulates lung cancer cell H69 growth and apoptosis by targeting WWOX gene and suppressing the ERK1/2 signaling pathway. target gene hsa-mir-208 "Carcinoma, Hepatocellular" 26169693 miR-208-3p promotes hepatocellular carcinoma cell proliferation and invasion through regulating ARID2 expression. target gene hsa-mir-144 Neoplasms [unspecific] 26169798 Our approach provides important insights into miRNAs and their role in regulatory networks. The methodology can be applied to systematically investigate the differences in target genes and pathways of arbitrary miRNA sets. target gene hsa-mir-205 Osteoporosis 26170952 The miR-205 antisense largely abolished the inhibitory effect of STAT3 activation on the levels of CHOP protein. target gene hsa-mir-7 Prostate Neoplasms 26172296 MicroRNA-7 inhibits the stemness of prostate cancer stem-like cells and tumorigenesis by repressing KLF4/PI3K/Akt/p21 pathway. target gene hsa-mir-133a "Carcinoma, Hepatocellular" 26173501 "MicroRNA-145 and MicroRNA-133a Inhibited Proliferation, Migration, and Invasion, While Promoted Apoptosis in Hepatocellular Carcinoma Cells Via Targeting FSCN1." target gene hsa-mir-145 "Carcinoma, Hepatocellular" 26173501 "MicroRNA-145 and MicroRNA-133a Inhibited Proliferation, Migration, and Invasion, While Promoted Apoptosis in Hepatocellular Carcinoma Cells Via Targeting FSCN1." target gene hsa-mir-18a Gastric Neoplasms 26173586 MicroRNA-18a modulates P53 expression by targeting IRF2 in gastric cancer patients. target gene hsa-mir-206 Coronary Artery Disease 26175229 "Role of the microRNA, miR-206, and its target PIK3C2¦Á in endothelial progenitor cell function ¨C potential link with coronary artery disease." target gene hsa-mir-17 Systemic Lupus Erythematosus 26175399 Targeting E2F1 and c-Myc expression by microRNA-17-5p represses interferon-stimulated gene MxA in peripheral blood mononuclear cells of pediatric systemic lupus erythematosus patients. target gene hsa-mir-139 Ischemic Heart Disease 26175501 "Gene enrichment studies of hsa-miR-139-5p,hsa-miR-483-3p targets demonstrated an association with cardiovascular disease, cell death,and metabolism." target gene hsa-mir-483 Ischemic Heart Disease 26175501 "Gene enrichment studies of hsa-miR-139-5p,hsa-miR-483-3p targets demonstrated an association with cardiovascular disease, cell death,and metabolism." target gene hsa-mir-302c Glioma 26176806 MiR-302c-3p suppresses invasion and proliferation of glioma cells via down-regulating metadherin (MTDH) expression. target gene hsa-mir-324 "Carcinoma, Hepatocellular" 26177288 MiR-324-5p Suppresses Hepatocellular Carcinoma Cell Invasion by Counteracting ECM Degradation through Post-Transcriptionally Downregulating ETS1 and SP1. target gene hsa-mir-203a Lung Neoplasms 26177443 "ERGIC3, which is regulated by miR-203a, is a potential biomarker for non-small cell lung cancer." target gene hsa-mir-129 Glioblastoma 26180082 Neurotensin signaling stimulates glioblastoma cell proliferation by upregulating c-Myc and inhibiting miR-29b-1 and miR-129-3p. target gene hsa-mir-29b-1 Glioblastoma 26180082 Neurotensin signaling stimulates glioblastoma cell proliferation by upregulating c-Myc and inhibiting miR-29b-1 and miR-129-3p. target gene hsa-mir-4487 Neuroblastoma 26183158 we identified that miR-4487 and miR-595 could target ULK1 and experimentally verified they could negatively or positively regulate ULK1-mediated autophagy target gene hsa-mir-595 Neuroblastoma 26183158 Identification of ULK1 as a novel biomarker involved in miR-4487 and miR-595 regulation in neuroblastoma SH-SY5Y cell autophagy. target gene hsa-mir-200a Lung Neoplasms 26184032 "MicroRNA-200a Targets EGFR and c-Met to Inhibit Migration, Invasion, and Gefitinib Resistance in Non-Small Cell Lung Cancer." target gene hsa-mir-16 Infection [unspecific] 26184511 miR- 16 targeted the 3â€?untranslated region of IL-6 and suppressed its translation in mesangial cells induced by SIgA. target gene hsa-mir-135b Atherosclerosis 26184978 MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C. target gene hsa-mir-499a Atherosclerosis 26184978 MiR-135b-5p and MiR-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C. target gene hsa-mir-34a Human Immunodeficiency Virus Infection 26188041 "The miRNA miR-34a enhances HIV-1 replication by targeting PNUTS/PPP1R10, which negatively regulates HIV-1 transcriptional complex formation." target gene hsa-mir-1238 Lung Neoplasms 26189214 miR-1238 inhibits cell proliferation by targeting LHX2 in non-small cell lung cancer. target gene hsa-mir-122a "Carcinoma, Hepatocellular" 26189916 Targeted Regression of Hepatocellular Carcinoma by Cancer-Specific RNA Replacement through miR-122a Regulation. target gene hsa-mir-302a Colorectal Carcinoma 26191138 Up-regulation of microRNA-302a inhibited the proliferation and invasion of colorectal cancer cells by regulation of the MAPK and PI3K/Akt signaling pathways. target gene hsa-mir-139 Oral Neoplasms 26191149 MiRNA-139 regulates oral cancer Tca8113 cells apoptosis through Akt signaling pathway. target gene hsa-mir-21 Cholangiocarcinoma 26191158 MicroRNA-21 regulates biological behavior by inducing EMT in human cholangiocarcinoma. target gene hsa-mir-199a Endometriosis 26191163 MiR-199a inhibits the angiogenic potential of endometrial stromal cells under hypoxia by targeting HIF-1¦Á/VEGF pathway. target gene hsa-mir-126 "Squamous Cell Carcinoma, Esophageal" 26191164 MicroRNA-126 is down-regulated in human esophageal squamous cell carcinoma and inhibits the proliferation and migration in EC109 cell via PI3K/AKT signaling pathway. target gene hsa-mir-182 "Carcinoma, Cervical" 26191165 miR-182 induces cervical cancer cell apoptosis through inhibiting the expression of DNMT3a. target gene hsa-mir-21 "Squamous Cell Carcinoma, Tongue" 26191167 Targeting miR-21 with AS-miR-21 suppresses aggressive growth of human tongue squamous cell carcinoma in vivo. target gene hsa-mir-26b "Carcinoma, Hepatocellular" 26191168 "MiR-26b inhibits hepatocellular carcinoma cell proliferation, migration, and invasion by targeting EphA2." target gene hsa-mir-365 Lymphoma 26191184 "MicroRNA-365 inhibits growth, invasion and metastasis of malignant melanoma by targeting NRP1 expression." target gene hsa-mir-191 Endometriosis 26191186 MiR-191 inhibits TNF-¦Á induced apoptosis of ovarian endometriosis and endometrioid carcinoma cells by targeting DAPK1. target gene hsa-mir-1297 "Carcinoma, Hepatocellular" 26191190 MicroRNA-1297 regulates hepatocellular carcinoma cell proliferation and apoptosis by targeting EZH2. target gene hsa-mir-204 Breast Neoplasms 26191195 MicroRNA-204 targets JAK2 in breast cancer and induces cell apoptosis through the STAT3/BCl-2/survivin pathway. target gene hsa-mir-185 Gastric Neoplasms 26191199 TRIM29 functions as an oncogene in gastric cancer and is regulated by miR-185. target gene hsa-mir-10b "Carcinoma, Gastric" 26191201 Augmented miR-10b expression associated with depressed expression of its target gene KLF4 involved in gastric carcinoma. target gene hsa-mir-107 "Carcinoma, Hepatocellular" 26191213 Our observations suggested that miR-107 could promote HCC cells proliferation via targeting Axin2 and might represent a potential therapeutic target for HCC. target gene hsa-mir-144 Lung Neoplasms 26191328 "Expression of miR-144 is reduced in malignant SPN tissues and peripheral blood, being of clinical value in the diagnosis of malignant SPN.miR-144 promotes the apoptosis of lung cancer cells, and inhibits the proliferation, invasion and migration of lung cancer by regulating ZEB1 gene." target gene hsa-mir-21 "Carcinoma, Colon" 26193421 The S100P/RAGE signaling pathway regulates expression of microRNA-21 in colon cancer cells. target gene hsa-mir-325 "Carcinoma, Hepatocellular" 26194496 These findings implied that miR-325 regulates cell invasion and proliferation via targeting HMGB1 and may be a potential prognostic marker for HCC. target gene hsa-mir-21 Neoplasms [unspecific] 26194786 "the miRNA-21 target is cyclically reused, and many MB-DNA fuel strands are attached to the sensor surface, leading to a significantly amplified current response for sensitive detection of miRNA-21 down to 1.4 fM. The developed sensor also shows high sequence discrimination capability and can be used to monitor miRNA-21 expression levels in cancer cells. Moreover, this sensor avoids the involvement of any enzymes for target recycling amplification and features with highly minimized background noise for miRNA detection, which makes this method hold great potential for convenient monitoring of different miRNA biomarkers for early diagnosis of various cancers." target gene hsa-mir-34a Bladder Neoplasms 26198939 MicroRNA-34a regulates cell cycle by targeting CD44 in human bladder carcinoma cells. target gene hsa-mir-720 Chronic Hepatitis B 26199080 therapies targeting miR-720 may help restore impaired immunity in chronic HBV infection (CHB) patients. target gene hsa-mir-29a Diabetes Mellitus 26199111 "Using gain- and loss-of-function studies, five of these genes were confirmed as endogenous targets of miR-29a" target gene hsa-mir-15b Japanese Encephalitis Virus Infection 26202983 MicroRNA-15b Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF125. target gene hsa-mir-200c Neoplasms [unspecific] 26203557 miR-200c dampens cancer cell migration via regulation of protein kinase A subunits. target gene hsa-mir-26b "Carcinoma, Ovarian" 26204489 MiR-26b/KPNA2 axis inhibits epithelial ovarian carcinoma proliferation and metastasis through downregulating OCT4. target gene hsa-mir-335 Neoplasms [unspecific] 26204513 Our data suggest that differences in response to miR-335 by tumor cells may lie in part in the mechanism of regulation of MT1-MMP production. target gene hsa-mir-539 Thyroid Neoplasms 26206083 MiR-539 inhibits thyroid cancer cell migration and invasion by directly targeting CARMA1. target gene hsa-mir-21 Pulmonary Hypertension 26208095 these results demonstrate that PPAR¦Ã ligands regulate proliferative responses to hypoxia by preventing hypoxic increases in miR-21 and reductions in PTEN. These findings further clarify molecular mechanisms that support targeting PPAR¦Ã to attenuate pathogenic derangements in PH. target gene hsa-mir-25 Glioblastoma 26209061 miR-25 promotes glioblastoma cell proliferation and invasion by directly targeting NEFL. target gene hsa-mir-1246 "Carcinoma, Lung, Non-Small-Cell" 26209100 "These results suggested that the miR-1246 may promote cell metastasis by targeting CPEB4. Meanwhile, the level of CPEB4 could be used as a potential marker in NSCLC patients. Our findings unraveled novel functions of miR-1246 in lung cancer cells and shed light on NSCLC prognosis." target gene hsa-mir-21 "Carcinoma, Hepatocellular" 26210448 MiR-21 promoted proliferation and migration in hepatocellular carcinoma through negative regulation of Navigator-3. target gene hsa-mir-205 Prostate Neoplasms 26211479 Editorial Comment to MicroRNA-205 inhibits cancer cell migration and invasion via modulation of centromere protein F regulating pathways in prostate cancer. target gene hsa-mir-29c Alzheimer Disease 26212654 miR-29c regulates NAV3 protein expression in a transgenic mouse model of Alzheimer's disease. target gene hsa-mir-335 Gastrointestinal Stromal Tumor 26214687 "Our results suggest that miR-34a and miR-335 are candidate tumor suppressive miRNAs in GISTs, and that they are frequent targets of epigenetic silencing in GISTs." target gene hsa-mir-34a Gastrointestinal Stromal Tumor 26214687 "Our results suggest that miR-34a and miR-335 are candidate tumor suppressive miRNAs in GISTs, and that they are frequent targets of epigenetic silencing in GISTs." target gene hsa-mir-194 "Carcinoma, Hepatocellular" 26221053 NF-¦ÊB signaling relieves negative regulation by miR-194 in hepatocellular carcinoma by suppressing the transcription factor HNF-1¦Á. target gene hsa-mir-143 Cardiovascular Diseases [unspecific] 26221598 We discuss the potential role of miR-143/-145 as valuable biomarkers for cardiovascular diseases and explore the potential strategy of targeting miR-143 and miR-145. target gene hsa-mir-145 Cardiovascular Diseases [unspecific] 26221598 We discuss the potential role of miR-143/-145 as valuable biomarkers for cardiovascular diseases and explore the potential strategy of targeting miR-143 and miR-145. target gene hsa-mir-223 Coronary Artery Disease 26221610 "our recent data demonstrated that the level of both intraplatelet and circulating miR-223 is an independent predictor for HTPR, thus providing a link between miR-223 and MACE. These lines of evidence indicate that miR-223 may serve as a potential regulatory target for HTPR, as well as a diagnostic tool for identification of HTPR in clinical settings." target gene hsa-mir-149 Ovarian Neoplasms 26223974 Our findings suggest that miRNA-149 mediates the susceptibility of paclitaxel by regulating MyD88 expression in ovarian cancer cells. target gene hsa-mir-375 "Carcinoma, Cervical" 26224081 miR-375 Modulates Radiosensitivity of HR-HPV-Positive Cervical Cancer Cells by Targeting UBE3A through the p53 Pathway. target gene hsa-mir-204 Pulmonary Hypertension 26224795 BRD4 expression in PAH is microRNA-204 dependent target gene hsa-mir-198 Neoplasms [unspecific] 26225959 we have identified that miR-198 inhibited HaCaT cell proliferation by directly targeting CCND2. target gene hsa-mir-320a "Leukemia, Myeloid, Chronic" 26228085 MicroRNA-320a acts as a tumor suppressor by targeting BCR/ABL oncogene in chronic myeloid leukemia. target gene hsa-mir-21 Bladder Neoplasms 26230405 microRNA-21 Regulates Cell Proliferation and Migration and Cross Talk with PTEN and p53 in Bladder Cancer. target gene hsa-mir-503 Prostate Neoplasms 26231797 miR-503 suppresses tumor cell proliferation and metastasis by directly targeting RNF31 in prostate cancer. target gene hsa-mir-214 "Squamous Cell Carcinoma, Esophageal" 26234674 Overexpression of miR-214-3p in esophageal squamous cancer cells enhances sensitivity to cisplatin by targeting survivin directly and indirectly through CUG-BP1. target gene hsa-mir-135a Lung Neoplasms 26235874 MiR-135a inhibits migration and invasion and regulates EMT-related marker genes by targeting KLF8 in lung cancer cells. target gene hsa-mir-219 "Carcinoma, Colon" 26238082 miR-219-5p plays a tumor suppressive role in colon cancer by targeting oncogene Sall4. target gene hsa-mir-497 Ovarian Neoplasms 26238185 MiR-497 decreases cisplatin resistance in ovarian cancer cells by targeting mTOR/P70S6K1. target gene hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 26238532 MicroRNA-145 inhibits migration and invasion via inhibition of fascin 1 protein expression in non-small-cell lung cancer cells. target gene hsa-mir-146a "Carcinoma, Lung, Non-Small-Cell" 26238771 MicroRNA-146a inhibits epithelial mesenchymal transition in non-small cell lung cancer by targeting insulin receptor substrate 2. target gene hsa-mir-138 "Squamous Cell Carcinoma, Oral" 26239136 miR-138 suppresses the proliferation of oral squamous cell carcinoma cells by targeting Yes-associated protein 1. target gene hsa-mir-126 "Carcinoma, Thyroid" 26239517 miR-126 inhibits papillary thyroid carcinoma growth by targeting LRP6. target gene hsa-mir-205 Breast Neoplasms 26239614 MicroRNA-205 inhibits the proliferation and invasion of breast cancer by regulating AMOT expression. target gene hsa-mir-29b-2 Glioblastoma 26240386 "our findings reveal a novel function of YB-1 in regulating non-coding RNA expression, which has important implications in tumorigenesis." target gene hsa-mir-224 "Squamous Cell Carcinoma, Esophageal" 26245343 "The current study demonstrated that miR-224 acts as an oncogenic miRNA in esophageal squamous cell carcinoma (ESCC), possibly by targeting PHLPP1 and PHLPP2." target gene hsa-mir-587 Colorectal Carcinoma 26247730 MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer. target gene hsa-mir-124 Colorectal Carcinoma 26248089 miR124 inhibits DNA synthesis and proliferation by reducing levels of pentose phosphate pathway enzymes in CRC cells. Expression of miR124 and its targets correlate with survival times and might be used in prognosis. target gene hsa-mir-200c "Carcinoma, Renal Cell" 26248649 miR-200c Targets CDK2 and Suppresses Tumorigenesis in Renal Cell Carcinoma. target gene hsa-mir-221 Multiple Myeloma 26249174 Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma. target gene hsa-mir-222 Multiple Myeloma 26249174 Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma. target gene hsa-mir-638 "Carcinoma, Gastric" 26250158 MicroRNA-638 inhibits cell proliferation by targeting phospholipase D1 in human gastric carcinoma. target gene hsa-mir-34c "Carcinoma, Lung, Non-Small-Cell" 26250586 "miR-34c-3p directly targeted eIF4E and reduced miR-34c-3p expression in NSCLC, promoting cell cycle progression, proliferation, migration and invasion." target gene hsa-mir-144 Glioblastoma 26250785 miR-144-3p exerts anti-tumor effects in glioblastoma by targeting c-Met. target gene hsa-mir-221 "Carcinoma, Hepatocellular" 26251599 Targeted delivery of chemically modified anti-miR-221 to hepatocellular carcinoma with negatively charged liposomes. target gene hsa-mir-24 Bladder Neoplasms 26252200 "MicroRNA-24 upregulation inhibits proliferation, metastasis and induces apoptosis in bladder cancer cells by targeting CARMA3." target gene hsa-mir-122 "Carcinoma, Hepatocellular" 26252254 MicroRNA-122 affects cell aggressiveness and apoptosis by targeting PKM2 in human hepatocellular carcinoma. target gene hsa-mir-21 Prostate Neoplasms 26252635 IL-6 Inhibits the Targeted Modulation of PDCD4 by miR-21 in Prostate Cancer. target gene hsa-mir-132 "Carcinoma, Hepatocellular" 26252738 "MiR-132 inhibits cell proliferation, invasion and migration of hepatocellular carcinoma by targeting PIK3R3." target gene hsa-mir-338 Breast Neoplasms 26252944 MicroRNA-338-3p functions as tumor suppressor in breast cancer by targeting SOX4. target gene hsa-let-7a Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-106a Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-124 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-126 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-135 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-142 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-145 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-146 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-150 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-155 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-193 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-21 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-221 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-223 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-29 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-365 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-375 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-452 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-615 Allergic Asthma 26253882 "miRNAs are important post-transcriptional regulators of gene expression and have a role in allergic type 2 immune responses through their activity in multiple immune and non-immune cell subsets. Detailed mechanistic studies are critically needed to understand and leverage miRNAs to advance the field and inform clinical investigation. miRNAs act through multiple direct targets to regulate networks of genes, and their specificity and potency depends on the dynamics of individual miRNA-target interactions. Identifying which miRNAs and which targets are important for promoting or restraining allergy will help to identify vulnerable nodes in allergic inflammation, enhancing our mechanistic understanding of miRNA in the immune system and providing novel, possibly druggable, targets for these increasingly prevalent diseases." target gene hsa-mir-130a Liver Fibrosis 26255201 These findings suggest that miR-130a and miR-130b are involved in downregulation of PPARγ in liver fibrosis. target gene hsa-mir-27b Liver Fibrosis 26255201 "In carbon tetrachloride injection (CCl4) and common bile duct ligation (CBDL) liver fibrosis models, miRNAs miR-130a, miR-130b, miR-301a, miR-27b and miR-340 levels were found to be increased and PPARγ expression decreased." target gene hsa-mir-378a Breast Neoplasms 26255816 miR-378a-3p modulates tamoxifen sensitivity in breast cancer MCF-7 cells through targeting GOLT1A. target gene hsa-mir-145 Intrahepatic Cholangiocarcinoma 26255969 MiR-145 functions as a tumor suppressor targeting NUAK1 in human intrahepatic cholangiocarcinoma. target gene hsa-mir-512 "Squamous Cell Carcinoma, Head and Neck" 26258591 miR-512-5p suppresses tumor growth by targeting hTERT in telomerase positive head and neck squamous cell carcinoma in vitro and in vivo. target gene hsa-mir-512 Alzheimer Disease 26258756 Reduced miR-512 and the Elevated Expression of Its Targets cFLIP and MCL1 Localize to Neurons With Hyperphosphorylated Tau Protein in Alzheimer Disease. target gene hsa-mir-99b Colorectal Carcinoma 26259252 miRNA-99b-5p suppresses liver metastasis of colorectal cancer by down-regulating mTOR. target gene hsa-mir-124 Osteosarcoma 26259653 MicroRNA-124 suppresses the migration and invasion of osteosarcoma cells via targeting ROR2-mediated non-canonical Wnt signaling. target gene hsa-mir-744 Inflammation 26259828 "our data indicate that by targeting PTP1B, miR-744 plays a feed-forward role in regulating type I IFN signaling pathway. These findings give us new insights into the functions of renal miRNAs in regulating important signaling pathways." target gene hsa-mir-338 "Carcinoma, Nasopharyngeal" 26260688 MicroRNA-338 inhibits migration and proliferation by targeting hypoxia-induced factor 1¦Á in nasopharyngeal carcinoma. target gene hsa-mir-155 Lymphoma 26261072 Oncogenic microRNA-155 and its target PU.1: an integrative gene expression study in six of the most prevalent lymphomas. target gene hsa-mir-7 "Carcinoma, Gastric" 26261179 MicroRNA-7/NF-¦ÊB signaling regulatory feedback circuit regulates gastric carcinogenesis. target gene hsa-mir-218 Gastric Neoplasms 26261515 These findings suggest that miR-218 inhibits MDR of gastric cancer cells by down-regulating SMO expression. target gene hsa-mir-15a Osteosarcoma 26261520 "MiRNA-15a inhibits proliferation, migration and invasion by targeting TNFAIP1 in human osteosarcoma cells." target gene hsa-mir-126 Breast Neoplasms 26261534 "Thus, our study revealed that miR-126 may act as a tumor suppressor via inhibition of cell invasion by downregulating ADAM9 in breast cancer development." target gene hsa-mir-630 Colorectal Carcinoma 26263387 CREB-miR-630-BCL2L2 and TP53RK comprise a novel signaling cascade regulating radiosensitivity in CRC cell lines by inducing cell apoptosis and death. target gene hsa-mir-17 Myocardial Infarction 26265044 "The delivery of exogenous miR-17 suppressed Apaf-1 expression and consequently attenuated formation of the apoptosome complex containing caspase-9, as demonstrated by co-immunoprecipitation and immunocytochemistry." target gene hsa-mir-106a Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-106b Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-125 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-126 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-143 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-145 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-17 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-18 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-19a Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-19b-1 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-20a Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-221 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-222 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-223 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-2861 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-3960 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-92-1 Cardiovascular Diseases [unspecific] 26266261 Our current special issue presents a series of original researches and reviews on recent advances in miRNAs regulating the pathophysiology aspects of CVD that will hopefully set the stage for future research initiatives aimed at expanding our understanding of these important mediators of cardiovascular function. target gene hsa-mir-138 "Squamous Cell Carcinoma, Cerevial" 26267680 "miR-138 and miR-720 are the down-regulated target miRNAs in HPV16-positive squamous carcinoma of the cervix in the Uygur of southern Xinjiang. The common target gene for miR-138 and miR-720 is EZH2, which might be related to cervical squamous carcinoma invasion and metastasis." target gene hsa-mir-720 "Squamous Cell Carcinoma, Cerevial" 26267680 "miR-138 and miR-720 are the down-regulated target miRNAs in HPV16-positive squamous carcinoma of the cervix in the Uygur of southern Xinjiang. The common target gene for miR-138 and miR-720 is EZH2, which might be related to cervical squamous carcinoma invasion and metastasis." target gene hsa-mir-503 Microvascular Disease 26268439 "Collectively, our data demonstrate that miR-503 regulates pericyte-endothelial crosstalk in microvascular diabetic complications." target gene hsa-mir-126 "Leukemia, Promyelocytic, Acute" 26274316 "These results demonstrate that ATO inhibits the growth of HUVECs and induces apoptosis by downregulating VEGFA. One mechanism by which this occurs is Ets-2 upregulation, which results in an increase in miR-126 levels and downregulation of VEGFA expression." target gene hsa-mir-202 Osteosarcoma 26276504 This study provides new insights into miRNA-202 in osteosarcoma as a potential molecular target for chemotherapy. target gene hsa-mir-761 "Carcinoma, Lung, Non-Small-Cell" 26278569 miR-761 promotes progression and metastasis of NSCLC by targeting ING4 and TIMP2. target gene hsa-mir-205 "Carcinoma, Laryngeal" 26281062 miRNA-205 might promote the proliferation of Hep-2 cells by regulating the expression of PTEN. target gene hsa-mir-185 Congenital Microtia 26282502 "The expression of has-miR-203, has-miR-200c and has-miR-451 were significantly different in microtia. Target gene of SOCS3, TFs of STAT1 and STAT2, and lncRNA of MALAT1 may play important roles in the development of the external ear." target gene hsa-mir-200c Congenital Microtia 26282502 "The expression of has-miR-203, has-miR-200c and has-miR-451 were significantly different in microtia. Target gene of SOCS3, TFs of STAT1 and STAT2, and lncRNA of MALAT1 may play important roles in the development of the external ear." target gene hsa-mir-203 Congenital Microtia 26282502 "The expression of has-miR-203, has-miR-200c and has-miR-451 were significantly different in microtia. Target gene of SOCS3, TFs of STAT1 and STAT2, and lncRNA of MALAT1 may play important roles in the development of the external ear." target gene hsa-mir-451 Congenital Microtia 26282502 "The expression of has-miR-203, has-miR-200c and has-miR-451 were significantly different in microtia. Target gene of SOCS3, TFs of STAT1 and STAT2, and lncRNA of MALAT1 may play important roles in the development of the external ear." target gene hsa-mir-664 Lymphoma 26287415 "Taken together, our results suggest that miR-664 may play an important role in suppressing proliferation of CMM cells and present a novel mechanism of miR-mediated direct suppression of PLP2 expression in cancer cells." target gene hsa-mir-215 Colorectal Carcinoma 26287603 Identification of miR-215 mediated targets/pathways via translational immunoprecipitation expression analysis (TrIP-chip). target gene hsa-mir-34a "Carcinoma, Rectal" 26287733 "Although miR-34a and miR-34c can regulate Axl expression in vitro,our data indicates that the miR-34 family members are not the primary regulators of Axl expression in RCC." target gene hsa-mir-411 Rhabdomyosarcoma 26291313 "These results establish an autoregulatory loop between TGF-¦Â1/miR-411-5p/SPRY4 and MAPK in RMS, which governs the switch between proliferation and differentiation." target gene hsa-mir-223 Tuberculosis 26296289 It is concluded that miR-223 can regulate macrophage function by inhibition of cytokine production and NF-¦ÊB activation. target gene hsa-let-7b Ischemia-Reperfusion Injury 26296645 we report that let-7b targets caspase-3 to regulate apoptosis and autophagy in MSCs exposed to ROS. target gene hsa-mir-139 Breast Neoplasms 26299922 MiR-139-5p not only attenuated the development of breast cancer cells but also mediated drug-resistance by regulating the expression of the downstream target gene Notch1. target gene hsa-mir-137 Osteosarcoma 26302771 "We revealed novel functional role of miR-137 in osteosarcoma regulation, likely through FXYD6 binding." target gene hsa-mir-155 Colorectal Carcinoma 26303353 "Thus, it is hypothesized that miR-155 may be a promising target for antagonizing COX-2 expression in colorectal and other cancers." target gene hsa-mir-195 "Colitis, Ulcerative" 26303523 miR-195 plays a role in steroid resistance of ulcerative colitis by targeting Smad7. target gene hsa-mir-203 "Carcinoma, Nasopharyngeal" 26304234 MiRNA-203 Reduces Nasopharyngeal Carcinoma Radioresistance by Targeting IL8/AKT Signaling. target gene hsa-mir-17 "Lymphoma, Large B-Cell, Diffuse" 26305986 "In the present review, we focus on the role of the miR-17-92 cluster in lymphoproliferative disorders, including diagnostic/prognostic implications, and on the potential applications of anti-miRNAs based therapies targeting miRNAs belonging to the cluster." target gene hsa-mir-18 "Lymphoma, Large B-Cell, Diffuse" 26305986 "In the present review, we focus on the role of the miR-17-92 cluster in lymphoproliferative disorders, including diagnostic/prognostic implications, and on the potential applications of anti-miRNAs based therapies targeting miRNAs belonging to the cluster." target gene hsa-mir-19a "Lymphoma, Large B-Cell, Diffuse" 26305986 "In the present review, we focus on the role of the miR-17-92 cluster in lymphoproliferative disorders, including diagnostic/prognostic implications, and on the potential applications of anti-miRNAs based therapies targeting miRNAs belonging to the cluster." target gene hsa-mir-19b-1 "Lymphoma, Large B-Cell, Diffuse" 26305986 "In the present review, we focus on the role of the miR-17-92 cluster in lymphoproliferative disorders, including diagnostic/prognostic implications, and on the potential applications of anti-miRNAs based therapies targeting miRNAs belonging to the cluster." target gene hsa-mir-20a "Lymphoma, Large B-Cell, Diffuse" 26305986 "In the present review, we focus on the role of the miR-17-92 cluster in lymphoproliferative disorders, including diagnostic/prognostic implications, and on the potential applications of anti-miRNAs based therapies targeting miRNAs belonging to the cluster." target gene hsa-mir-92-1 "Lymphoma, Large B-Cell, Diffuse" 26305986 "In the present review, we focus on the role of the miR-17-92 cluster in lymphoproliferative disorders, including diagnostic/prognostic implications, and on the potential applications of anti-miRNAs based therapies targeting miRNAs belonging to the cluster." target gene hsa-mir-214 Huntington Disease 26307536 "In summary, we have shown that increased expression of miR-214 observed in HD cell model could target MFN2, altered mitochondrial morphology and deregulated cell cycle. Inhibition of miR-214 could be a possible target of intervention in HD pathogenesis." target gene hsa-mir-712 Atherosclerosis 26308181 Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE(-/-) Mice. target gene hsa-mir-15a Pituitary Neoplasms 26309203 GAA-induced decrease in cell proliferation is associated with decreased expression of Bcl-2 and increased miR-15a. target gene hsa-mir-18a Leukemia 26314433 The miR-18a can regulated the sensitivity of leukemia HL-60 cells to VP-16 and VCR by targeting ATM. target gene hsa-mir-26a "Lymphoma, T-Cell" 26314438 that abnormal expression of miR-26a may participate in genesis and development of ENKTCL through regulating the expression of its target gene CDK6. target gene hsa-mir-23a "Carcinoma, Nasopharyngeal" 26314966 MiR-23a sensitizes nasopharyngeal carcinoma to irradiation by targeting IL-8/Stat3 pathway. target gene hsa-mir-99b "Squamous Cell Carcinoma, Oral" 26315788 miRNA-99b-3p functions as a potential tumor suppressor by targeting glycogen synthase kinase-3¦Â in oral squamous cell carcinoma Tca-8113 cells. target gene hsa-mir-340 "Carcinoma, Esophageal" 26316084 MiR-340 functions as a tumor suppressor by modulating the expression of PSAT1 and may contribute to the progression and invasiveness of ESCC. target gene hsa-mir-130b Lupus Nephritis 26316103 MiR-130b-3p negatively regulated ERBB2IP expression by directly targeting the 3'-UTR of ERBB2IP The circulating miR-130b-3p might serve as a biomarker and play an important role in renal damage in early stage LN patients. target gene hsa-mir-10a "Carcinoma, Lung, Non-Small-Cell" 26317552 We found that PTEN was a direct target of miR-10a in NSCLC. Also miR-10a activated the PTEN/AKT/ERK pathway. We suggest that miR-10a contributes to NSCLC by targeting PTEN. target gene hsa-mir-494 Chondrosarcoma 26317788 MicroRNA-494 inhibits cell proliferation and invasion of chondrosarcoma cells in vivo and in vitro by directly targeting SOX9. target gene hsa-mir-940 Gastric Neoplasms 26317898 MicroRNA-940 promotes tumor cell invasion and metastasis by downregulating ZNF24 in gastric cancer. target gene hsa-mir-134 Breast Neoplasms 26318721 MicroRNA-134 modulates resistance to doxorubicin in breast cancer cells by downregulating the expression of ABCC1 which is known to encode the multidrug resistance-associated protein 1. target gene hsa-mir-34a "Squamous Cell Carcinoma, Head and Neck" 26323460 MicroRNA-34a regulates epithelial-mesenchymal transition and cancer stem cell phenotype of head and neck squamous cell carcinoma in vitro. target gene hsa-mir-542 "Carcinoma, Esophageal" 26323919 "Taken together, our results indicated that miR-542-3p is a tumor suppressor of esophageal cancer acting at steps that regulate cell growth." target gene hsa-mir-155 Tuberculosis 26324048 "From these results, it was concluded that mycobacteria can improve the level of miR-155, while BCG can induce apoptosis in THP-1 cells. The results suggested FOXO3 is a downstream target gene of miR-155, which combines 3'-UTRs to inhibit the expression of FOXO3." target gene hsa-mir-34a "Carcinoma, Colon" 26324236 These findings demonstrate that miR-34a may act as a negative regulator in colon cancer by targeting PDGFRA. target gene hsa-mir-221 Prostate Neoplasms 26325107 Loss of the tumour-suppressive miR-221/222 cluster enhanced migration and invasion in PCa cells. Our data describing targets regulated by the tumour-suppressive miR-221/222 cluster provide insights into the mechanisms of PCa and CRPC progression. target gene hsa-mir-222 Prostate Neoplasms 26325107 Loss of the tumour-suppressive miR-221/222 cluster enhanced migration and invasion in PCa cells. Our data describing targets regulated by the tumour-suppressive miR-221/222 cluster provide insights into the mechanisms of PCa and CRPC progression. target gene hsa-mir-206 Neoplasms [unspecific] 26325180 "Taken together, our results demonstrated that miR-206 suppressed c-Met and Bcl2 expression in NSCLS and could function as a potent tumor suppressor in c-Met/Bcl2-over expressing tumors. Inhibition of miR-206 function could contribute to aberrant cell proliferation, migration, invasion and apoptosis,leading to NSCLS development." target gene hsa-mir-1908 Osteosarcoma 26328886 "Collectively, the results showed that, miR-1908 promotes proliferation and invasion of osteosarcoma cells by repressing PTEN expression." target gene hsa-mir-372 "Carcinoma, Renal Cell" 26332146 Our data indicated that miR-372 seemed to function as a tumour suppressor in renal cell carcinoma progression by inhibiting the IGF2BP1 expression. target gene hsa-mir-29a "Scleroderma, Systemic" 26335042 miRNA-29a in systemic sclerosis: A valid target. target gene hsa-mir-212 Pancreatic Neoplasms 26337469 Pancreatic cancer-derived exosomes transfer miRNAs to dendritic cells and inhibit RFXAP expression via miR-212-3p. target gene hsa-mir-1207 "Carcinoma, Lung, Non-Small-Cell" 26338522 "The three miR-1207-5p, miR-1228* and miR-939 are the most connected miRNA that regulated a large number of genes." target gene hsa-mir-1228 "Carcinoma, Lung, Non-Small-Cell" 26338522 "The three miR-1207-5p, miR-1228* and miR-939 are the most connected miRNA that regulated a large number of genes." target gene hsa-mir-939 "Carcinoma, Lung, Non-Small-Cell" 26338522 "The three miR-1207-5p, miR-1228* and miR-939 are the most connected miRNA that regulated a large number of genes." target gene hsa-mir-182 Lung Neoplasms 26338969 These results suggest that modulation of miR-182 and miR-185 and their target genes may contribute to lung carcinogenesis attributable to PM2.5 exposure. target gene hsa-mir-185 Lung Neoplasms 26338969 These results suggest that modulation of miR-182 and miR-185 and their target genes may contribute to lung carcinogenesis attributable to PM2.5 exposure. target gene hsa-mir-124 Osteosarcoma 26339404 Our findings may help to understand the molecular mechanisms of OS and identify targets of effective targeted therapies for OS. target gene hsa-mir-19b Osteosarcoma 26339404 Our findings may help to understand the molecular mechanisms of OS and identify targets of effective targeted therapies for OS. target gene hsa-mir-20a Osteosarcoma 26339404 Our findings may help to understand the molecular mechanisms of OS and identify targets of effective targeted therapies for OS. target gene hsa-mir-155 Colorectal Carcinoma 26340059 We further showed that miR-155 acted to repress the Warburg effect through the mechanism of inactivating the IL-6/STAT3 pathway. target gene hsa-mir-200a "Squamous Cell Carcinoma, Esophageal" 26341629 These results reaffirm the potential role of MSA as a chemopreventive agent via the regulation of KLF4/miR-200a/Keap1/Nrf2 axis in ESCC cells. target gene hsa-mir-21 "Carcinoma, Esophageal" 26345812 "Together,these results suggest that miR- 21 might be involved in the development and metastasis of esophageal cancer, through interaction with its PDCD4 and K-ras target genes." target gene hsa-mir-101 Lung Neoplasms 26349988 miR-101 represses lung cancer by inhibiting interaction of fibroblasts and cancer cells by down-regulating CXCL12. target gene hsa-mir-16 Osteoarthritis 26350536 Our results indicate that miR-16-5p is an important regulator of SMAD3 expression in human chondrocytes and may contribute to the development of OA. target gene hsa-mir-128 Colorectal Carcinoma 26352220 "Taken together, these data suggested that miR-128 serves as a tumor suppressor and blocks CRC growth and metastasis by targeting IRS1." target gene hsa-mir-675 Breast Neoplasms 26353930 H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b. target gene hsa-mir-183 Endometriosis 26357653 "These findings, together with the fact that ITGB1 is a critical factor for cell adhesion and invasiveness, suggest that miR-183 may be involved in the development of endometriosis by regulating ITGB1 in endometrial stromal cells." target gene hsa-mir-10b Breast Neoplasms 26359455 Combining miR-10b-Targeted Nanotherapy with Low-Dose Doxorubicin Elicits Durable Regressions of Metastatic Breast Cancer. target gene hsa-mir-326 Gastric Neoplasms 26359764 "Our study demonstrated that miR-326 overexpression was a poor prognostic marker for gastric cancer patients, and miR-326 served as a tumor suppressor in gastric cancer via directly regulating FSCN1." target gene hsa-mir-506 Gastric Neoplasms 26362716 "In conclusion, miR-506 was identified as an ETS1 targeting suppressor of metastatic invasion and angiogenesis in gastric cancer." target gene hsa-mir-21 Breast Neoplasms 26363493 An immobilization-free electrochemical impedance biosensor based on duplex-specific nuclease assisted target recycling for amplified detection of microRNA. target gene hsa-mir-19a Lung Neoplasms 26367773 Uncovering Direct Targets of MiR-19a Involved in Lung Cancer Progression. target gene hsa-mir-141 Ischemic Heart Disease 26371161 MicroRNA-141 regulates the expression level of ICAM-1 on endothelium to decrease myocardial ischemia-reperfusion injury. target gene hsa-mir-203 Osteosarcoma 26382657 "Take together, our results demonstrated that miR-203 act as a tumor suppressor miRNA through regulating RAB22A expression and suggested its involvement in osteosarcoma progression and carcinogenesis." target gene hsa-mir-21 Coronary Artery Disease 26383248 "Because the smad7 expression pattern was similar to that of TGF-¦Â,our study suggests that miR-21 can negatively regulate the frequency of circulating Treg cells through a TGF-¦Â1/smad-independent signaling pathway in PBMCs." target gene hsa-mir-34a "Carcinoma, Hepatocellular" 26385595 MiR-34a is Involved in the Decrease of ATP Contents Induced by Resistin Through Target on ATP5S in HepG2 Cells. target gene hsa-mir-519c Colorectal Carcinoma 26386386 Exploiting a novel miR-519c-HuR-ABCG2 regulatory pathway to overcome chemoresistance in colorectal cancer. target gene hsa-mir-185 "Carcinoma, Nasopharyngeal" 26390174 "Combined low miR-185-3p and miR-324-3p might be important markers for prediction of low response to RT/CRT and poor overall survival and recurrence-free survival.MiR-185-3p and miR-324-3p can modulate NPC cell growth and apoptosis, at least partly through targeting SMAD7." target gene hsa-mir-324 "Carcinoma, Nasopharyngeal" 26390174 "Combined low miR-185-3p and miR-324-3p might be important markers for prediction of low response to RT/CRT and poor overall survival and recurrence-free survival.MiR-185-3p and miR-324-3p can modulate NPC cell growth and apoptosis, at least partly through targeting SMAD7." target gene hsa-mir-10b Breast Neoplasms 26392359 Our work provides evidence for the involvement of specific miRNAs in triple-negative breast cancer development through regulating BRCA1 expression. target gene hsa-mir-146a Breast Neoplasms 26392359 Our work provides evidence for the involvement of specific miRNAs in triple-negative breast cancer development through regulating BRCA1 expression. target gene hsa-mir-153 Breast Neoplasms 26392359 Our work provides evidence for the involvement of specific miRNAs in triple-negative breast cancer development through regulating BRCA1 expression. target gene hsa-mir-26a Breast Neoplasms 26392359 Our work provides evidence for the involvement of specific miRNAs in triple-negative breast cancer development through regulating BRCA1 expression. target gene hsa-mir-32 Neoplasms [unspecific] 26394836 SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes target gene hsa-mir-590 Neoplasms [unspecific] 26394836 SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes target gene hsa-mir-133b Ovarian Neoplasms 26396496 "MicroRNA-133b may reduce ovarian cancer drug resistance by silencing the expression of the drug-resistance-related proteins, GST-¦Ð and MDR1. In future, the combination of miR-133b with chemotherapy agents may prevent the development of drug resistance in ovarian cancers." target gene hsa-mir-205 "Carcinoma, Adrenocortical" 26397843 "In conclusion, miR-205 suppresses the growth of ACC SW-13 cells via targeting the anti-apoptotic gene Bcl-2." target gene hsa-mir-18a Colorectal Carcinoma 26398009 "These findings demonstrate that miR-18a exhibits a protective role in CRC via inhibiting proliferation, invasion and migration of CRC cells by directly targeting the TBPL1 gene." target gene hsa-mir-125a Gastric Neoplasms 26398444 "Collectively, our results indicated that miR-125a regulated the paracrine of VEGF-A in gastric cancer and thereby controlled the angiogenesis of the tumor." target gene hsa-mir-222 Alzheimer Disease 26398571 "In conclusion, these results suggest that the abnormal expression of miR-222 may contribute to dysregulation of the cell-cycle in AD, at least in part by affecting the expression of p27Kip1." target gene hsa-mir-211 "Carcinoma, Hepatocellular" 26398845 miR-211 promotes invasion of carcinoma cells by directly targeting ESR1. target gene hsa-mir-200c Pancreatic Neoplasms 26400206 "More importantly, garcinol treatment led to the upregulation of several tumor suppressor microRNAs, and miR-200c increased by garcinol treatment was found to target and downregulate Notch1." target gene hsa-mir-200c Breast Neoplasms 26400441 PDCD10 is a target gene of miR-200c and also a possible mechanism by which miR-200c plays a role in regulating the stemness of BCSCs and MaSCs. target gene hsa-mir-34c Alzheimer Disease 26402112 MicroRNA-34c Downregulation Ameliorates Amyloid-¦Â-Induced Synaptic Failure and Memory Deficits by Targeting VAMP2. target gene hsa-mir-140 Colorectal Carcinoma 26402430 Our results suggested a tumor suppressive role of miR-140-5p in CRC tumorigenesis and progression by targeting VEGFA. target gene hsa-mir-100 Gastric Neoplasms 26404754 This study demonstrated that miR-100 could be induced by C/EBP¦Á and may act as a tumor suppressor gene by inhibiting ZBTB7A. target gene hsa-mir-584 "Carcinoma, Thyroid" 26405762 "These results indicate that miR-584 could inhibit the expression of ROCK1, and ROCK1 knockdown would further affect the migration ability of K1 cells." target gene hsa-mir-217 Lung Neoplasms 26415832 "The results indicate that miR-217 regulation of EZH2/H3K27me3 via MALAT1 is involved in CSE-induced EMT and malignant transformation of HBE cells. The posttranscriptional silencing of MALAT1 by miR-217 provides a link, through EZH2,between ncRNAs and the EMT and establishes a mechanism for CSE-induced lung carcinogenesis." target gene hsa-mir-25 Lung Neoplasms 26416661 Elevated microRNA-25 inhibits cell apoptosis in lung cancer by targeting RGS3. target gene hsa-mir-21 "Carcinoma, Colon" 26418978 "MiR-21 can mediate the drug resistance to 5-FU by inhibiting its target PDCD4,which can regulate the expression of ABCC5 and CD44 genes." target gene hsa-mir-96 "Carcinoma, Renal Cell" 26419932 These results suggest that miR-96 suppresses RCC invasion by modulating Ezrin expression. target gene hsa-mir-21 Colorectal Carcinoma 26419959 Our data support a possible role of tumor epigenetic deregulation by noncoding RNA in suppressing the antitumor T-cell-mediated adaptive immune response and suggest MIR21 as a potential target for immunotherapy and prevention in colorectal cancer. target gene hsa-mir-222 "Carcinoma, Hepatocellular" 26420065 all the four miRNAs synergistically target PBX3 target gene hsa-mir-21 Polycystic Ovarian Syndrome 26427146 "In comparison with normal subjects, serum miR-21 is obviously increased in PCOS patients. Through targeting LATS1, miR-21 could prompt PCOS progression and could act as a novel non-invasive biomarker for diagnosis of PCOS." target gene hsa-mir-135b "Carcinoma, Hepatocellular" 26429530 miR-135b promotes the invasion and metastasis possibly by targeting the Hippo pathway genes. target gene hsa-mir-133 Roberts Syndrome 26434741 miR-133-dependent cx43 overexpression rescues esco2-dependent growth defects target gene hsa-mir-130a Chronic Inflammation 26436920 "Therefore,miR-142-5p and miR-130a-3p regulate macrophage profibrogenic gene expression in chronic inflammation." target gene hsa-mir-142 Chronic Inflammation 26436920 "Therefore,miR-142-5p and miR-130a-3p regulate macrophage profibrogenic gene expression in chronic inflammation." target gene hsa-mir-92 Breast Neoplasms 26437339 miR-92 is gradually lost in breast epithelial cells during cancer progression correlating with a shift in ER¦Â1 immunoreactivity from nuclei to the cytoplasm. Our data support a functional role in fibroblasts where modification of miR-92 expression can influence the invasive capacity of breast cancer epithelial cells. However in silico analysis suggests that ER¦Â1 may not be the most important miR-92 target in breast cancer. target gene hsa-mir-137 Astrocytoma 26440052 miR-137 acts as a tumor suppressor in astrocytoma by targeting RASGRF1. target gene hsa-mir-145 Lung Neoplasms 26440147 "In aggregate, our results attribute to miR-145-5p and its direct targets pivotal roles in malignancy progression and in metastasis." target gene hsa-mir-133a Heart Failure 26440278 miR-133a acts as a repressor of SRF and CTGF expression target gene hsa-mir-139 Glioblastoma 26449464 We concluded that ectopic expression of miR-139-5p in GBM cell lines significantly suppressed cell proliferation and inducing apoptosis. Bioinformatics coupled with luciferase and western blot assays also revealed that miR-139-5p suppresses glioma cell proliferation by targeting ELTD1 and regulating cell cycle. target gene hsa-mir-93 Glioma 26449498 "In conclusion, our results suggest an increasing role of miR-93 in regulating the level of expression of several genes involved in the angiogenesis of gliomas." target gene hsa-mir-19b "Carcinoma, Hepatocellular" 26453548 "The overexpression of miR-19b was significantly correlated with better disease-free and overall survival in patients with HCC presenting with vascular invasion or multifocal disease after curative surgery. MiR-19b may influence the expression of NDRG1, EPCAM, HMGB2, HIF1A, and MAPK14." target gene hsa-mir-29c Uterine Leiomyoma 26453978 "MiR-29c expression is suppressed in leiomyoma, resulting in an increase in expression of its targets COL3A1 and DNMT3A. The suppression of miR-29c in LSMC is primarily mediated by SP1, NF-¦ÊB signaling, and epigenetic modification. Collectively, these results indicate a significant role for miR-29c in leiomyoma pathogenesis." target gene hsa-mir-302b "Carcinoma, Hepatocellular" 26457704 This study showed that miR-302b could enhance the sensitivity to 5-FU in HCC cell lines and verified its two putative targeted genes responsible for its 5-FU sensitivity. target gene hsa-mir-26a Gastric Neoplasms 26458859 "Our results suggest that miR-26a can improve the sensitivity of GC cells to cisplatin-based chemotherapies through targeting NRAS and E2F2, and provide the first evidence of the potential utility of miR-26a as a sensitizer in chemotherapy for GC." target gene hsa-let-7a Breast Neoplasms 26460550 "Our research revealed the mechanisms through which miR-208a functioned in breast cancer and BrCSCs, and identified the miR-208a-SOX2/¦Â-catenin-LIN28-let-7a-DICER1 regulatory feedback loop in regulations of stem cells renewal." target gene hsa-mir-208a Breast Neoplasms 26460550 "Our research revealed the mechanisms through which miR-208a functioned in breast cancer and BrCSCs, and identified the miR-208a-SOX2/¦Â-catenin-LIN28-let-7a-DICER1 regulatory feedback loop in regulations of stem cells renewal." target gene hsa-mir-101 Gastric Neoplasms 26460960 "We conclude that miR-27b,miR-101 and miR-128 inhibit angiogenesis by down-regulating VEGF-C expression in gastric cancers." target gene hsa-mir-128 Gastric Neoplasms 26460960 "We conclude that miR-27b,miR-101 and miR-128 inhibit angiogenesis by down-regulating VEGF-C expression in gastric cancers." target gene hsa-mir-27b Gastric Neoplasms 26460960 "We conclude that miR-27b,miR-101 and miR-128 inhibit angiogenesis by down-regulating VEGF-C expression in gastric cancers." target gene hsa-mir-221 Cardiovascular Diseases [unspecific] 26461283 "Among differentially-expressed miRNAs are those involved in the regulation of inflammation or cell adhesion, such as miR-221 and miR-181." target gene hsa-mir-7 "Carcinoma, Lung, Non-Small-Cell" 26464649 This study further extends the biological role of miR-7 in NSCLC A549 and H460 cells and identifies BCL-2 as a novel target possibly involved in miR-7-mediated growth suppression and apoptosis induction of NSCLC cells. target gene hsa-mir-29 Neoplasms [unspecific] 26470025 MiR-29 restrained K562 cell growth and proliferation. MiR-29 induced K562 cell apoptosis through down-regulating FoxM1. target gene hsa-mir-182 Ovarian Neoplasms 26472020 "In normal FTSE cells, miR-182 overexpression triggers cellular senescence by p53-mediated upregulation of p21." target gene hsa-mir-320a "Carcinoma, Cervical" 26472185 CREB1-driven expression of miR-320a promotes mitophagy by down-regulating VDAC1 expression during serum starvation in cervical cancer cells. target gene hsa-mir-378g Neoplasms [unspecific] 26473472 "MiR-378g enhanced radiosensitivity partially by targeting SHP-1 in NPC cells. Cell invasion was also partially inhibited by miR-378g, but the effect was not mediated by SHP-1." target gene hsa-mir-30a Neoplasms [unspecific] 26473838 "In summary, we uncovered the protective function of miR30a targeting NFATc3 in the regulation of podocyte injury response to EMT." target gene hsa-mir-138 Prostate Neoplasms 26474967 "miR-138 specifically targeted K2 and inhibited its expression, thereby regulating a miR-138/K2/β1-integrin signaling axis in mCRPC that is critical for the modulation of sensitivity to chemotherapeutics." target gene hsa-mir-1 Cardiomegaly 26476318 "Further findings indicated that miR-1, which was depressed by Nkx2.5, might play a fundamental role in mediating cardiac hypertrophy and arrhythmia via its target genes Mef2a and Irx5 after HBCD treatment." target gene hsa-mir-1271 Ovarian Neoplasms 26477861 Low levels of miR-1271 in ovarian cancer tissues promoted cancer cell growth. MiR-1271 may be a new predictor of prognosis in ovarian cancer.MiR-1271 exerted its role by targeting CCNG1. target gene hsa-mir-125b Sepsis 26482503 miR-125b modulates PCT expression by manipulating the amount and transcriptional activity of Stat3. target gene hsa-mir-19a Atherosclerosis 26483345 Endothelial Hypoxia-Inducible Factor-1¦Á Promotes Atherosclerosis and Monocyte Recruitment by Upregulating MicroRNA-19a. target gene hsa-mir-342 Lung Neoplasms 26483346 miR-342-3p regulates MYC transcriptional activity via direct repression of E2F1 in human lung cancer. target gene hsa-mir-30 Atherosclerosis 26488467 Upregulation of miR-30 by HFD may impair the protective effects of endothelial cell autophagy against development of atherosclerosis through suppressing protein translation of ATG6. target gene hsa-mir-146a Osteoarthritis 26492575 "Simply, hypoxia induced HIF-1α, and HIF-1α increased miR-146a, but miR-146a suppressed Bcl-2, an autophagy inhibitor." target gene hsa-mir-124 Colorectal Carcinoma 26497367 "In conclusion, our data showed that miR-124 and miR-506 inhibit progression and increase sensitivity to chemotherapy by targeting DNMT3B and DNMT1 in CRC. These findings may provide novel avenues for the development of targeted therapies." target gene hsa-mir-506 Colorectal Carcinoma 26497367 "In conclusion, our data showed that miR-124 and miR-506 inhibit progression and increase sensitivity to chemotherapy by targeting DNMT3B and DNMT1 in CRC. These findings may provide novel avenues for the development of targeted therapies." target gene hsa-mir-331 "Carcinoma, Hepatocellular" 26497554 "Upregulated in Hepatitis B virus-associated hepatocellular carcinoma cells,miR-331-3p promotes proliferation of hepatocellular carcinoma cells by targeting ING5." target gene hsa-mir-155 "Lymphoma, B-Cell" 26497687 "miR-155 targeting of DET1, NIAM, TRIM32, HOMEZ, PSIP1 and JARID2." target gene hsa-mir-139 Lung Neoplasms 26497851 "Taken together, our results demonstrated that miR-139-5p plays a pivotal role in lung cancer through inhibiting cell proliferation, metastasis, and promoting apoptosis by targeting oncogenic c-Met." target gene hsa-mir-542 Osteosarcoma 26498360 "Taken together, our results indicated that miR-542-5p plays a critical role in the proliferation of osteosarcoma and targets HUWE1." target gene hsa-mir-652 Pancreatic Neoplasms 26498682 MiR-652 inhibits acidic microenvironment-induced epithelial-mesenchymal transition of pancreatic cancer cells by targeting ZEB1. target gene hsa-mir-34a Prostate Neoplasms 26499184 "Collectively, miR-34a enhances chemosensitivity by directly downregulating ATG4B-induced autophagy through AMPK/mTOR pathway in PCa." target gene hsa-mir-616 "Carcinoma, Hepatocellular" 26499912 "Based on these results, we conclude that miR-616 is a promising prognostic biomarker of HCC and targeting miR-616 may be a potential option to prevent the progression of HCC." target gene hsa-mir-519 "Leukemia, Myeloid, Acute" 26499919 The results of the present study indicate that miR-519 may contribute to HL60 cell apoptosis by regulating the expression of HuR. target gene hsa-mir-221 Choriocarcinoma 26501139 "In conclusion, our results suggested that miR-221 promotes EMT through targeting PTEN and forms a positive feedback loop with ¦Â-catenin/c-Jun signaling pathway in EHCC." target gene hsa-mir-19a "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 26502748 "Our preliminary outcomes suggest the utility of miR-19a in the challenging differential diagnosis of laryngeal VSCC. Although miR-19a has been found to regulate SOCS-1 expression, this evidence was not confirmed by this investigation." target gene hsa-mir-449a Glioma 26502848 "The expression of microRNA-449a is low in patients with glioma,which may inhibit the proliferation of glioma and promote its cell apoptosis via affecting the expression of PKC¦Á." target gene hsa-mir-221 Breast Neoplasms 26503209 "a pro-apoptotic Bcl-2 family protein, was up-regulated by the knockdown of miR-221." target gene hsa-mir-154 "Carcinoma, Hepatocellular" 26503460 "In conclusion, these results indicate that miR-154 functions as a tumor suppressor in HCC by suppressing ZEB2,suggesting that miR-154 may serve as a potential target for HCC." target gene hsa-mir-125b Gastric Neoplasms 26504803 miR-125b Suppresses Proliferation and Invasion by Targeting MCL1 in Gastric Cancer. target gene hsa-mir-223 Tuberculosis 26505221 "Our data provide new clues for the essential role of miR-223 in the regulation of anti-Mtb-directed immune responses, which relies on the regulation of FOXO3 expression." target gene hsa-mir-223 Prostate Neoplasms 26509963 Tumor-suppressive microRNA-223 inhibits cancer cell migration and invasion by targeting ITGA3/ITGB1 signaling in prostate cancer. target gene hsa-mir-7 "Carcinoma, Breast, Triple Negative" 26513016 "Our results not only revealed IL-6 as a key regulator of lapatinib-induced metastasis, but also explored the requirement of miR7/Raf-1/MAPK/AP-1 axis in lapatinib-induced IL-6 expression." target gene hsa-mir-30a Enterovirus Infection 26515789 "We provided further evidence that by modulating cellular miR-30a level through either overexpression or inhibition, one can inhibit or promote EV71 replication, respectively, through regulating autophagic activity." target gene hsa-mir-451 Breast Neoplasms 26516138 "Increased miR-451 expression may negatively regulate Bcl-2 mRNA and protein expression, followed by affecting the protein expression of caspase 3,and accelerate the apoptosis in breast cancer, indicating that miR-451 might influence the drug resistances of the Paclitaxel-resistant breast cancer cell line." target gene hsa-mir-182 Hepatitis C Virus Infection 26518141 "miR-182 was never investigated before, neither in HCV infection nor in NK cells, and we found it to have dysregulated expression in both liver tissues and NK cells of HCV-infected patients compared to control. In addition to that, miR-182 was found to have a contradicting effect in both effector cell and its HCV-infected target cell regarding HCV replication." target gene hsa-mir-346 "Carcinoma, Cervical" 26518874 miR-346 Up-regulates Argonaute 2 (AGO2) Protein Expression to Augment the Activity of Other MicroRNAs (miRNAs) and Contributes to Cervical Cancer Cell Malignancy. target gene hsa-mir-27b Atherosclerosis 26520906 The results presented here provide evidence that short-term modulation of miR-27b expression in wild-type mice regulates hepatic LDLR and ABCA1 expression but does not influence plasma and hepatic lipid levels. target gene hsa-mir-126 Systemic Lupus Erythematosus 26531267 miRNA-126 expression is reduced in SLE patients. miRNA-126 may be involved in the initiation and development of SLE by inhibiting the production of IFN. target gene hsa-mir-125b Breast Neoplasms 26531722 miR-125a-5p/miR-125b suppress the expression of TSTA3 target gene hsa-mir-21 Breast Neoplasms 26531758 "In conclusion, our results demonstrated that plasma miR-21 levels may serve as a diagnostic marker in breast cancers, whereas miR-21 promotes breast cancer cell proliferation and invasion by suppressing smad7, which enhances EGF and TGF-¦Â pathways." target gene hsa-mir-19 Pancreatic Neoplasms 26531836 A positive feedback loop of p53/miR-19/TP53INP1 modulates pancreatic cancer cell proliferation and apoptosis. target gene hsa-let-7b Prostate Neoplasms 26540468 "Finally, we hypothesized that miR-218, miR-145, miR-197, miR-149, miR-122, and let-7b may contribute to the development of CRPC through the influence of Ras, Rho proteins,and the SCF complex. Further investigation is needed to verify the functions of the identified novel pathways in CRPC development." target gene hsa-mir-122 Prostate Neoplasms 26540468 "Finally, we hypothesized that miR-218, miR-145, miR-197, miR-149, miR-122, and let-7b may contribute to the development of CRPC through the influence of Ras, Rho proteins,and the SCF complex. Further investigation is needed to verify the functions of the identified novel pathways in CRPC development." target gene hsa-mir-124 Prostate Neoplasms 26540468 "Finally, we hypothesized that miR-218, miR-145, miR-197, miR-149, miR-122, and let-7b may contribute to the development of CRPC through the influence of Ras, Rho proteins,and the SCF complex. Further investigation is needed to verify the functions of the identified novel pathways in CRPC development." target gene hsa-mir-125b Prostate Neoplasms 26540468 "Finally, we hypothesized that miR-218, miR-145, miR-197, miR-149, miR-122, and let-7b may contribute to the development of CRPC through the influence of Ras, Rho proteins,and the SCF complex. Further investigation is needed to verify the functions of the identified novel pathways in CRPC development." target gene hsa-mir-145 Prostate Neoplasms 26540468 "Finally, we hypothesized that miR-218, miR-145, miR-197, miR-149, miR-122, and let-7b may contribute to the development of CRPC through the influence of Ras, Rho proteins,and the SCF complex. Further investigation is needed to verify the functions of the identified novel pathways in CRPC development." target gene hsa-mir-149 Prostate Neoplasms 26540468 "Finally, we hypothesized that miR-218, miR-145, miR-197, miR-149, miR-122, and let-7b may contribute to the development of CRPC through the influence of Ras, Rho proteins,and the SCF complex. Further investigation is needed to verify the functions of the identified novel pathways in CRPC development." target gene hsa-mir-197 Prostate Neoplasms 26540468 "Finally, we hypothesized that miR-218, miR-145, miR-197, miR-149, miR-122, and let-7b may contribute to the development of CRPC through the influence of Ras, Rho proteins,and the SCF complex. Further investigation is needed to verify the functions of the identified novel pathways in CRPC development." target gene hsa-mir-218 Prostate Neoplasms 26540468 "Finally, we hypothesized that miR-218, miR-145, miR-197, miR-149, miR-122, and let-7b may contribute to the development of CRPC through the influence of Ras, Rho proteins,and the SCF complex. Further investigation is needed to verify the functions of the identified novel pathways in CRPC development." target gene hsa-mir-340 "Squamous Cell Carcinoma, Oral" 26541225 The findings suggest that miR-340 might act as a molecular switch that contributes to the regulation of glycolysis in OSCC by regulating Glut1 expression. target gene hsa-mir-381 Kidney Neoplasms 26541837 "MiRNA-381 can inhibit cell invasion in renal cancer by block the function of CBP, ¦Â-catenin and LEF-1." target gene hsa-mir-33a "Carcinoma, Cervical" 26541838 "Twist1 is critical for the invasiveness of cervical cancer cells;miR-33a, as a tumor suppressor gene, functions as an upstream regulator of Twist1 and is involved in the invasiveness of cervical cancer cell." target gene hsa-mir-506 Liver Neoplasms 26549227 "Thus, we conclude that miR-506 depresses the angiogenesis of liver cancer through targeting 3'UTR of SPHK1 mRNA. Our finding provides new insights into the mechanism of tumor angiogenesis." target gene hsa-mir-21 Breast Neoplasms 26549725 "Our data suggest that miR-21 expression is increased in breast cancer and plays an important role as a tumor gene by targeting STAT3, which may act as a double-response controller in breast cancer." target gene hsa-mir-150 Inflammation 26549736 "miR-150 can effectively prevent CD28/B7 co-stimulatory signaling transduction, decrease production of inflammatory cytokines, such as IL-2 and TNF, and elicit the induction of immune tolerance." target gene hsa-mir-133a Vascular Hypertrophy 26553694 Of 37 direct targets of miR-133a defined in unstressed hearts target gene hsa-mir-30a Preeclampsia 26555189 MiR-30a attenuates immunosuppressive functions of IL-1¦Â-elicited mesenchymal stem cells via targeting TAB3 target gene hsa-mir-590 Glioblastoma 26556542 "miR-590-3p suppresses cancer cell migration, invasion and epithelial-mesenchymal transition in glioblastoma multiforme by targeting ZEB1 and ZEB2." target gene hsa-mir-21 Glioblastoma 26558781 "Further, analysis of the miR-21-Sox2 relationship in mouse neural stem cells and in the mouse brain at different developmental stages indicates that miR-21 and Sox2 are predominantly expressed in mutually exclusive patterns, suggesting a role in normal neural development." target gene hsa-mir-29b Gastric Neoplasms 26564501 miR-29b can enhance the sensitivity of S gastric cancer cell by directly targeting PI3K/Akt pathway. target gene hsa-mir-181b Breast Neoplasms 26572075 "In summary, the results of the present study suggest that miR-181b functions as an oncogene during breast cancer development, and the miR-181b/Bim pathway may be a novel target used to overcome the chemoresistance in breast cancer." target gene hsa-mir-214 Cardiomegaly 26572862 These results provide the first clear link between miRNAs and direct regulation of XBP1 in heart failure and reveal that miR-214 and miR-30* synergistically regulates cardiac VEGF expression and angiogenesis by targeting XBP1 in the progression from adaptive hypertrophy to heart failure. target gene hsa-mir-214 Heart Failure 26572862 These results provide the first clear link between miRNAs and direct regulation of XBP1 in heart failure and reveal that miR-214 and miR-30* synergistically regulates cardiac VEGF expression and angiogenesis by targeting XBP1 in the progression from adaptive hypertrophy to heart failure. target gene hsa-mir-30 Cardiomegaly 26572862 These results provide the first clear link between miRNAs and direct regulation of XBP1 in heart failure and reveal that miR-214 and miR-30* synergistically regulates cardiac VEGF expression and angiogenesis by targeting XBP1 in the progression from adaptive hypertrophy to heart failure. target gene hsa-mir-30 Heart Failure 26572862 These results provide the first clear link between miRNAs and direct regulation of XBP1 in heart failure and reveal that miR-214 and miR-30* synergistically regulates cardiac VEGF expression and angiogenesis by targeting XBP1 in the progression from adaptive hypertrophy to heart failure. target gene hsa-mir-130a Ovarian Neoplasms 26573160 "NRP1 is targeted by miR-130a and miR-130b, and is associated with multidrug resistance in epithelial ovarian cancer based on integrated gene network analysis." target gene hsa-mir-130b Ovarian Neoplasms 26573160 "NRP1 is targeted by miR-130a and miR-130b, and is associated with multidrug resistance in epithelial ovarian cancer based on integrated gene network analysis." target gene hsa-mir-101 Gastric Neoplasms 26573417 "In conclusion, the results of the present study suggested that miR-101 inhibited the proliferation and promoted DDP-induced apoptosis of DDP-resistant gastric cancer cells, at least in part via targeting VEGF-C." target gene hsa-mir-382 Ovarian Neoplasms 26575700 "these findings revealed that miR-382 inhibits migration and invision by targeting ROR1 through regulating EMT in ovarian cancer, and might serve as a tumor suppressor in ovarian cancer." target gene hsa-mir-181a "Leukemia, Lymphoblastic, Acute" 26580398 ectopic expression of miR-181a also resulted in decreased CD10 hyperexpression in ETV6/RUNX1+ primary patient samples. target gene hsa-mir-197 Enterovirus Infection 26581983 Host MicroRNA miR-197 Plays a Negative Regulatory Role in the Enterovirus 71 Infectious Cycle by Targeting the RAN Protein. target gene hsa-mir-3151 Malignant Neoplasms [unspecific] 26582795 "In conclusion, we identify miR-3151 as a previously unidentified player in MM and PTC pathogenesis, which is driven by BRAF-dependent and BRAF-independent mechanisms. Characterization of TP53 as a downstream effector of miR-3151 provides evidence for a causal link between BRAF mutations and TP53 inactivation." target gene hsa-mir-661 Glioma 26585488 "These results indicate that miR-661 can inhibit glioma cell proliferation,migration and invasion by targeting hTERT." target gene hsa-mir-196b "Carcinoma, Lung, Non-Small-Cell" 26586336 homeobox A9 (HOXA9) as a target gene of miR-196b target gene hsa-mir-205 Neoplasms [unspecific] 26586569 miR-205 is upregulated upon NF-κB activation and suppresses COMMD1 expression in stemness-enriched cancer cells. target gene hsa-mir-124 Alzheimer Disease 26592243 "our study indicates that miR-124 plays neuroprotective roles in AD Drosophila by targeting Delta in Notch signaling pathway, which helps further our understanding of miRNAs in the molecular pathology of AD." target gene hsa-mir-762 Breast Neoplasms 26597380 These results demonstrate that miR-762 tumour effect was achieved by targeting IRF7 in human breast cancer specimens. target gene hsa-mir-211 Melanoma 26599548 Overexpression of mature miR-211 in Bcl-2 overexpressing cells rescued Bcl-2 ability to increase cell migration. target gene hsa-mir-203 Bladder Neoplasms 26599571 "In conclusion, decreased miR-203 predicts progression and poor prognosis for BC patients treated with cisplatin-based chemotherapy while miR-203 overexpression can enhance cisplatin sensitization by promoting apoptosis via directly targeting Bcl-w and Survivin." target gene hsa-mir-302c Influenza 26602079 Mir-302c mediates influenza A virus-induced IFN¦Â expression by targeting NF-¦ÊB inducing kinase. target gene hsa-mir-181c Neoplasms [unspecific] 26607087 Transfection with miR-181 mimics can suppress glycolysis in CAFs by inhibiting HK2 expression. target gene hsa-mir-4458 "Carcinoma, Colon" 26607110 "In conclusion, our findings suggested that miR-4458 inhibited the progression of colon cancer cells by inhibition of glycolysis and lactate production via directly targeting HK2 mRNA." target gene hsa-mir-99 Neoplasms [unspecific] 26608597 "We have developed an efficient SVM-based model for miRNA target prediction using recent CLIP-seq data, demonstrating superior performance, evaluated using ROC curves, specifically about 20 % better than the state-of-the-art, for different species (human or mouse), or different target types (canonical or non-canonical). To the best of our knowledge we provide the first distributed framework for microRNA target prediction based on Apache Hadoop and Spark." target gene hsa-mir-200c Pancreatic Neoplasms 26609108 "Paradoxically, targeting eIF4E, the best-characterized effector of MNKs, increases ZEB1 mRNA expression through repression of ZEB1-targeting miRNAs, miR-200c and miR-141." target gene hsa-mir-200b Retinal Degeneration 26617758 MiR-200b can regulate RECs growth and proliferation by changing VEGF and TGF¦Â1 expression to delay DR. target gene hsa-mir-133b Ovarian Neoplasms 26617770 "Altogether, our results indicated that miR-133b overexpression was shown to inhibit proliferation and invasion of OC cells through suppression of the MAPK and PI3K/Akt signaling pathways by targeting EGFR." target gene hsa-mir-203 Chronic Obstructive Pulmonary Disease 26617776 miR-203 represses NF-¦ÊB signaling via targeting TAK1 and PI3KCA and miR-203 overexpression may contribute to the COPD initiation. target gene hsa-mir-631 Prostate Neoplasms 26620225 "In all, our study demonstrates that miR-631 decreases PCa cell migration and invasion by dampening ZAP70 expression." target gene hsa-mir-181b "Carcinoma, Lung, Non-Small-Cell" 26620926 "Consequently, miR-181b functions as a tumor suppressor and has an important role in proliferation, chemosensitivity to DDP and metastasis of NSCLC by targeting TGF¦ÂR1/Smad signaling pathway." target gene hsa-mir-181b Acute Lung Injury 26622531 he overexpression of miR-181b resulted in the induction of an increment in interleukin (IL)-6 levels. target gene hsa-mir-143 "Squamous Cell Carcinoma, Oral" 26625772 "Low levels of miR-380-5p and miR-504 that directly target the 3'UTR of TP53 suggest that p53 may not be repressed by these two miRNAs in OSCC. On the other hand, low levels of miR-34a or miR-143 may relieve MDM4 and SIRT1 or MDM2 respectively, which will sequester p53 indicating an indirect mode of p53 suppression in oral tumors." target gene hsa-mir-34a "Squamous Cell Carcinoma, Oral" 26625772 "Low levels of miR-380-5p and miR-504 that directly target the 3'UTR of TP53 suggest that p53 may not be repressed by these two miRNAs in OSCC. On the other hand, low levels of miR-34a or miR-143 may relieve MDM4 and SIRT1 or MDM2 respectively, which will sequester p53 indicating an indirect mode of p53 suppression in oral tumors." target gene hsa-mir-151a Asthenozoospermia 26626315 These results indicate that miR-151a-5p may participate in the regulation of cellular respiration and ATP production through targeting Cytb. target gene hsa-mir-186 Ovarian Neoplasms 26626440 Our results are the first to demonstrate that miR-186 may sensitize ovarian cancer cell to paclitaxel and cisplatin by targeting ABCB1 and modulating the expression of GST-¦Ð. target gene hsa-mir-96 "Squamous Cell Carcinoma, Tongue" 26629033 MiR-96 is confirmed to be a direct target of MTSS1 gene and could regulate MTSS1 mediated Tca8113 cells proliferation and metastasis. target gene hsa-mir-16 Cervical Neoplasms 26629104 CCNE1 gene is targeted by miR-16-1 in CC cells. target gene hsa-mir-212 Post-Traumatic Stress Disorder 26632874 "DICER1 is an enzyme that generates mature microRNAs (miRNAs), which regulate gene expression post-transcriptionally in brain and other tissues and is involved in synaptic maturation and plasticity. Here, through genome-wide differential gene expression survey of post-traumatic stress disorder (PTSD) with comorbid depression (PTSD&Dep), we find that blood DICER1 expression is significantly reduced in cases versus controls, and replicate this in two independent cohorts. " target gene hsa-mir-3130 Post-Traumatic Stress Disorder 26632874 "DICER1 is an enzyme that generates mature microRNAs (miRNAs), which regulate gene expression post-transcriptionally in brain and other tissues and is involved in synaptic maturation and plasticity. Here, through genome-wide differential gene expression survey of post-traumatic stress disorder (PTSD) with comorbid depression (PTSD&Dep), we find that blood DICER1 expression is significantly reduced in cases versus controls, and replicate this in two independent cohorts. " target gene hsa-mir-153 Neuroblastoma 26633009 A Proteomics Approach to Investigate miR-153-3p and miR-205-5p Targets in Neuroblastoma Cells. target gene hsa-mir-205 Neuroblastoma 26633009 A Proteomics Approach to Investigate miR-153-3p and miR-205-5p Targets in Neuroblastoma Cells. target gene hsa-mir-150 Prostate Neoplasms 26636522 Increased miR-150 expression might participate in the development and progression of human prostate CSC by suppressing p27. This supported our previous study which found miR-150 was positively correlated with prostate tumor recurrence or metastasis. target gene hsa-mir-375 Lung Neoplasms 26642205 "Thus, our study demonstrates the differential expression profiles of miR-375 in 3 subtypes of lung carcinomas and finds thatmiR-375 directly targets ITPKB and promoted cell growth in SCLC cell line." target gene hsa-mir-512 "Carcinoma, Lung, Non-Small-Cell" 26648284 "In conclusion, our present study revealed miR-512-5p was able to target p21 to induce apoptosis and inhibit glycolysis in A549 and H1299 cell lines." target gene hsa-mir-1908 Renal Fibrosis 26648305 miR-1908 could inhibit renal fibrosis through targeting TGF-¦Â1. target gene hsa-mir-200b Glioma 26648487 MicroRNA-200b inhibits the growth and metastasis of glioma cells via targeting ZEB2. target gene hsa-mir-1290 "Squamous Cell Carcinoma, Esophageal" 26653554 "Taken together, our findings suggested that miR-1290 functions as a tumor oncogene in the progression of ESCC by targeting NFIX." target gene hsa-mir-30b Osteoarthritis 26653555 "In conclusion, miR-30b was involved in the process of OA, and it probably functioned through its target gene ERG." target gene hsa-mir-130b Glioma 26653558 "In conclusion, miR-130b is an independent prognostic biomarker for indicating survival of glioma patients and promotes glioma cell migration and invasion by targeting PPAR¦Ã." target gene hsa-mir-193a Lung Neoplasms 26655272 "Overall, we concluded that UCA1 functions as an oncogene in NSCLC, acting mechanistically by upregulating ERBB4 in part through 'spongeing' miR-193a-3p." target gene hsa-mir-127 Neoplasms [unspecific] 26655997 "Restoration of miR-127-3p and miR-376a-3p counteracts the neoplastic phenotype of giant cell tumor of bone derived stromal cells by targeting COA1, GLE1 and PDIA6." target gene hsa-mir-376a Neoplasms [unspecific] 26655997 "Restoration of miR-127-3p and miR-376a-3p counteracts the neoplastic phenotype of giant cell tumor of bone derived stromal cells by targeting COA1, GLE1 and PDIA6." target gene hsa-mir-142 "Carcinoma, Breast" 26657485 "microRNA miR-142-3p Inhibits Breast Cancer Cell Invasiveness by Synchronous Targeting of WASL, Integrin Alpha V, and Additional Cytoskeletal Elements. HrC-9698" target gene hsa-mir-31 Lung Neoplasms 26657862 Our study distinguishes miR-31 as a driver of lung tumorigenesis that promotes mutant KRAS-mediated oncogenesis and reveals that miR-31 directly targets and reduces expression of negative regulators of RAS/MAPK signaling. target gene hsa-mir-31 Neoplasms [unspecific] 26663584 "We identified VAV3, a regulator of actin remodeling and MRTF-A activity, as a miR-31 target." target gene hsa-mir-34a Lung Neoplasms 26667302 "Therefore, we propose that AXL is autoregulated by miR-34a in a feedback loop; this may provide a novel opportunity for developing AXL-targeted anticancer therapies." target gene hsa-mir-29 "Squamous Cell Carcinoma, Lung" 26676674 Elucidation of the novel lung SCC molecular pathways and targets regulated by tumor-suppressive miR-29s will provide new insights into the potential mechanisms of oncogenesis and metastasis of the disease. target gene hsa-mir-203 Glioma 26678661 "These data demonstrate that miR-203 potentially controls DNA damage repair via the PI3K/AKT and JAK/STAT3 pathways and may collectively contribute to the modulation of radiation sensitivity in MG cells by inhibiting DNA damage repair, prosurvival signaling, and epithelium-mesenchyme transition. Taken together, these findings demonstrate that miR-203 could be a target for overcoming the radiation resistance of GBM." target gene hsa-mir-26b Osteosarcoma 26681033 "miR- 26b may inhibit osteosarcoma cell proliferation, migration, and invasion by regulating PFKFB3 protein expression.miR-26b may have a tumor suppressor role in tumor occurrence and development." target gene hsa-mir-145 Glioblastoma 26681767 ISO attenuated SOX2 expression by specific induction of miR-145 target gene hsa-mir-494 Neoplasms [unspecific] 26686085 the regulatory effect of p100 on PTEN expression is mediated by its downregulation of miR-494 as a result of the inactivation of extracellular signal-regulated kinase 2 target gene hsa-mir-15a Neoplasms [unspecific] 26686086 In vivo inhibition of a PPARγ-regulated miR-15a/angiopoietin-1 pathway blocked increased angiogenesis and MSC expansion. target gene hsa-mir-27a Neoplasms [unspecific] 26687066 "Importantly, we find that Six1 expression leads to marked resistance to therapies targeting the p53-MDM2 interaction. Thus, we identify a competitive mechanism of p53 regulation, which may have consequences for drugs aimed at reinstating p53 function in tumours." target gene hsa-mir-21 Multiple Myeloma 26687742 "STAT3 and hsa-miR-125b, PIAS3 and hsa-miR-21 respectively formed self adaptation feedback regulations." target gene hsa-mir-155 Asthma 26693910 MicroRNA Expression Is Altered in an Ovalbumin-Induced Asthma Model and Targeting miR-155 with Antagomirs Reveals Cellular Specificity. target gene hsa-mir-155 "Squamous Cell Carcinoma, Head and Neck" 26694378 MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma. target gene hsa-mir-106a "Squamous Cell Carcinoma, Head and Neck" 26694379 MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma. target gene hsa-mir-125b "Squamous Cell Carcinoma, Head and Neck" 26694379 MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma. target gene hsa-mir-15b "Squamous Cell Carcinoma, Head and Neck" 26694379 MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma. target gene hsa-mir-193b "Squamous Cell Carcinoma, Head and Neck" 26694379 MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma. target gene hsa-mir-20b "Squamous Cell Carcinoma, Head and Neck" 26694379 MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma. target gene hsa-mir-548b "Squamous Cell Carcinoma, Head and Neck" 26694379 MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma. target gene hsa-mir-582 "Squamous Cell Carcinoma, Head and Neck" 26694379 MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma. target gene hsa-mir-9-1 "Squamous Cell Carcinoma, Head and Neck" 26694379 MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma. target gene hsa-mir-9-2 "Squamous Cell Carcinoma, Head and Neck" 26694379 MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma. target gene hsa-mir-27b Diabetic Retinopathy 26696637 "The authors assessed 155 baseline or DR progressors and 145 control samples (selected from 3,326 study participants) for a panel of 29 candidate miRNAs that were based on previous studies related to diabetes and myocardial infarction. They identified miR-27b and miR-320a as being significantly and independently associated with high DR risk. Complementing this analysis, they also elucidated the potential mechanism using cultured human endothelial cells and identified antiangiogenic thrombospondin-1 as a common target of these two miRNAs." target gene hsa-mir-320a Diabetic Retinopathy 26696637 "The authors assessed 155 baseline or DR progressors and 145 control samples (selected from 3,326 study participants) for a panel of 29 candidate miRNAs that were based on previous studies related to diabetes and myocardial infarction. They identified miR-27b and miR-320a as being significantly and independently associated with high DR risk. Complementing this analysis, they also elucidated the potential mechanism using cultured human endothelial cells and identified antiangiogenic thrombospondin-1 as a common target of these two miRNAs." target gene hsa-mir-155 "Carcinoma, Nasopharyngeal" 26698246 This study found that aberrant miR-155 expression driven by LMP1 can modulate radio-sensitivity of the NPC cell at least partly through targeting UBQLN1. target gene hsa-mir-705 Osteoporosis 26700816 "Mechanistically, TNF-¦Á activated NF-¦ÊB pathway to promote microRNA-705 expression, which function as a repressor of FoxO1 through post-transcriptional regulation." target gene hsa-mir-21 Glioma 26701969 "These findings suggest that miR-21 is linked to glioma angiogenesis,that miR-21 is unlikely to regulate PTEN, and that miR-21-positive tumor cells do not possess stem cell characteristics." target gene hsa-mir-218 Iron Metabolism Disease 26703568 "Taken together, our results show that miR-218 inhibits erythroid differentiation and alters iron metabolism by targeting ALAS2 in K562 cells." target gene hsa-mir-125b "Carcinoma, Hepatocellular" 26704017 miR-125b has been reported to down-regulate SIRT7 by binding to its 3'UTR target gene hsa-mir-1275 Lymphoma 26705180 "MiR-664b-5p, miR-1275, miR-4739, miR-4736 and miR-504-5p may become an important indicator in the differentiation ALK-negative anaplastic large cell lymphoma from CD30-positive peripheral T cell lymphoma (not otherwise specified).MiR-4739, miR-4736 and miR-1275 may play important role in pathogenesis of negative-anaplastic large cell lymphoma by target genes: TNFRSF8 and TMOD1." target gene hsa-mir-4736 Lymphoma 26705180 "MiR-664b-5p, miR-1275, miR-4739, miR-4736 and miR-504-5p may become an important indicator in the differentiation ALK-negative anaplastic large cell lymphoma from CD30-positive peripheral T cell lymphoma (not otherwise specified).MiR-4739, miR-4736 and miR-1275 may play important role in pathogenesis of negative-anaplastic large cell lymphoma by target genes: TNFRSF8 and TMOD1." target gene hsa-mir-4739 Lymphoma 26705180 "MiR-664b-5p, miR-1275, miR-4739, miR-4736 and miR-504-5p may become an important indicator in the differentiation ALK-negative anaplastic large cell lymphoma from CD30-positive peripheral T cell lymphoma (not otherwise specified).MiR-4739, miR-4736 and miR-1275 may play important role in pathogenesis of negative-anaplastic large cell lymphoma by target genes: TNFRSF8 and TMOD1." target gene hsa-mir-504 Lymphoma 26705180 "MiR-664b-5p, miR-1275, miR-4739, miR-4736 and miR-504-5p may become an important indicator in the differentiation ALK-negative anaplastic large cell lymphoma from CD30-positive peripheral T cell lymphoma (not otherwise specified).MiR-4739, miR-4736 and miR-1275 may play important role in pathogenesis of negative-anaplastic large cell lymphoma by target genes: TNFRSF8 and TMOD1." target gene hsa-mir-664b Lymphoma 26705180 "MiR-664b-5p, miR-1275, miR-4739, miR-4736 and miR-504-5p may become an important indicator in the differentiation ALK-negative anaplastic large cell lymphoma from CD30-positive peripheral T cell lymphoma (not otherwise specified).MiR-4739, miR-4736 and miR-1275 may play important role in pathogenesis of negative-anaplastic large cell lymphoma by target genes: TNFRSF8 and TMOD1." target gene hsa-mir-106b Liver Transplant Rejection 26707312 "These results suggest that miR-18b, miR-340, and miR-106b, which regulate the expression of specific immunophenotypes, can be used as potential biomarkers to identify long-term stable liver transplant recipients from recipients with acute rejection." target gene hsa-mir-18b Liver Transplant Rejection 26707312 "These results suggest that miR-18b, miR-340, and miR-106b, which regulate the expression of specific immunophenotypes, can be used as potential biomarkers to identify long-term stable liver transplant recipients from recipients with acute rejection." target gene hsa-mir-340 Liver Transplant Rejection 26707312 "These results suggest that miR-18b, miR-340, and miR-106b, which regulate the expression of specific immunophenotypes, can be used as potential biomarkers to identify long-term stable liver transplant recipients from recipients with acute rejection." target gene hsa-mir-205 Osteosarcoma 26708425 "In conclusion, our study suggested that miR-205 may function as a tumor suppressor via targeting TGF-¦Á in OS, and the abnormal expression of miR-205 might be a key factor in OS progression." target gene hsa-mir-363 Gastric Neoplasms 26709677 MiR-363-3p showed low levels in GC tissues and cells. Enforced expression of miR-363-3p inhibited cell growth and migration of GC cells and vice versa. NOTCH1 is the targeted gene of miR-363-3p. CONCLUSIONS MiR-363-3p plays a tumor suppressor role in GC. target gene hsa-mir-135b "Carcinoma, Breast, Triple Negative" 26711213 "The expressions of miRNA-135b were higher in most triple-negative breast cancer cell lines than others. miRNA-135b could promote the proliferation,invasion and migration in triple-negative breast cancer cell lines MDA-MB-231 and MDA-MB-468, and APC was one of the target genes of miRNA- 135b by participating in the process of regulation." target gene hsa-mir-199a Ovarian Neoplasms 26711828 "miR-199a regulates the sensitivity of ovarian cancer cells to cisplatin through modulating expression of mTOR, and involves in the cisplatin resistance process of ovarian cancer cells." target gene hsa-mir-125a Leukemia 26713860 miR-125a suppressed Zbtb7a expression through its direct binding to the Zbtb7a-3'UTR. target gene hsa-mir-125a Neoplasms [unspecific] 26713860 miR-125a suppressed Zbtb7a expression through its direct binding to the Zbtb7a-3'UTR. target gene hsa-mir-150 "Carcinoma, Cervical" 26715362 "Taken together, our data demonstrated that elevated miR-150 targets FOXO4 expression and therefore regulates multiple genes expression, resulting in cervical cancer cell growth and survival." target gene hsa-mir-663 Glioblastoma 26717894 "MicroRNA-663 inhibits the proliferation, migration and invasion of glioblastoma cells via targeting TGF-¦Â1." target gene hsa-mir-92a Intracranial Aneurysm 26718427 "In conclusion, our research demonstrated that miR-92a and KLF2 were negative correlation in intracranial aneurysm model, and miR-92a could directly target KLF2 in endothelial cells through complementary sequence of 3'UTR region." target gene hsa-mir-331 Colorectal Carcinoma 26718987 "Overall, we identified that miR-331-3p is underexpressed in CRC and contributes to cell growth regulation by targeting HER2 through activating the PI3K/Akt and ERK1/2 signaling pathways." target gene hsa-mir-129 Breast Neoplasms 26720492 The miR-129-5p/HMGB1 axis can regulate irradiation-induced autophagy in breast cancer and might be an important pathway in regulating radiosensitivity of breast cancer cells. target gene hsa-mir-194 "Carcinoma, Hepatocellular" 26722431 MicroRNA-194 acts as a prognostic marker and inhibits proliferation in hepatocellular carcinoma by targeting MAP4K4. target gene hsa-mir-592 "Carcinoma, Hepatocellular" 26722432 MicroRNA-592 targets DEK oncogene and suppresses cell growth in the hepatocellular carcinoma cell line HepG2. target gene hsa-mir-214 Glioma 26722446 "In summary, our data indicate that miR-214 may function as tumor suppressor in glioma by targeting PCBP2." target gene hsa-mir-34c "Carcinoma, Hepatocellular" 26722462 "miR-34c-3p inhibits cell proliferation, migration and invasion of hepatocellular carcinoma by targeting MARCKS." target gene hsa-mir-204 "Carcinoma, Esophageal" 26722467 miR-204 inhibits invasion and epithelial-mesenchymal transition by targeting FOXM1 in esophageal cancer. target gene hsa-mir-140 Lung Neoplasms 26722475 "MicroRNA-140-3p inhibits proliferation, migration and invasion of lung cancer cells by targeting ATP6AP2." target gene hsa-mir-365 Osteosarcoma 26728377 miR-365 could inhibit the proliferation and promote the apoptosis in SOSP-9607 osteosarcoma cells probably by mediating the expression of KRAS. target gene hsa-let-7b Retinoblastoma 26730174 "Several critical miRNAs were identified in RB progression.Hsa-miR-373 might regulate RB invasion and metastasis, hsa-miR-181a might involve in the CDKN1B-mediated cell cycle pathway, and hsa-miR-125b and hsa-let-7b might serve as tumor suppressors by coregulating CDK6, CDC25A, and LIN28A. The miRNAs hsa-miR-25, hsa-miR-18a, and hsa-miR-20a might exert their function by coregulating BCL2L1." target gene hsa-mir-125b Retinoblastoma 26730174 "Several critical miRNAs were identified in RB progression.Hsa-miR-373 might regulate RB invasion and metastasis, hsa-miR-181a might involve in the CDKN1B-mediated cell cycle pathway, and hsa-miR-125b and hsa-let-7b might serve as tumor suppressors by coregulating CDK6, CDC25A, and LIN28A. The miRNAs hsa-miR-25, hsa-miR-18a, and hsa-miR-20a might exert their function by coregulating BCL2L1." target gene hsa-mir-18a Retinoblastoma 26730174 "Several critical miRNAs were identified in RB progression.Hsa-miR-373 might regulate RB invasion and metastasis, hsa-miR-181a might involve in the CDKN1B-mediated cell cycle pathway, and hsa-miR-125b and hsa-let-7b might serve as tumor suppressors by coregulating CDK6, CDC25A, and LIN28A. The miRNAs hsa-miR-25, hsa-miR-18a, and hsa-miR-20a might exert their function by coregulating BCL2L1." target gene hsa-mir-20a Retinoblastoma 26730174 "Several critical miRNAs were identified in RB progression.Hsa-miR-373 might regulate RB invasion and metastasis, hsa-miR-181a might involve in the CDKN1B-mediated cell cycle pathway, and hsa-miR-125b and hsa-let-7b might serve as tumor suppressors by coregulating CDK6, CDC25A, and LIN28A. The miRNAs hsa-miR-25, hsa-miR-18a, and hsa-miR-20a might exert their function by coregulating BCL2L1." target gene hsa-mir-25 Retinoblastoma 26730174 "Several critical miRNAs were identified in RB progression.Hsa-miR-373 might regulate RB invasion and metastasis, hsa-miR-181a might involve in the CDKN1B-mediated cell cycle pathway, and hsa-miR-125b and hsa-let-7b might serve as tumor suppressors by coregulating CDK6, CDC25A, and LIN28A. The miRNAs hsa-miR-25, hsa-miR-18a, and hsa-miR-20a might exert their function by coregulating BCL2L1." target gene hsa-mir-373 Retinoblastoma 26730174 "Several critical miRNAs were identified in RB progression.Hsa-miR-373 might regulate RB invasion and metastasis, hsa-miR-181a might involve in the CDKN1B-mediated cell cycle pathway, and hsa-miR-125b and hsa-let-7b might serve as tumor suppressors by coregulating CDK6, CDC25A, and LIN28A. The miRNAs hsa-miR-25, hsa-miR-18a, and hsa-miR-20a might exert their function by coregulating BCL2L1." target gene hsa-mir-31 "Carcinoma, Thyroid, Papillary" 26731986 Down regulation of miR-31 contributed to the malignant progression of papillary thyroid carcinoma cells by targeting HuR. target gene hsa-mir-935 "Carcinoma, Gastric, Signet Ring Cell" 26742429 miR-935 suppresses gastric signet ring cell carcinoma tumorigenesis by targeting Notch1 expression. target gene hsa-mir-193a "Carcinoma, Esophageal" 26743123 miR-193a-3p regulation of chemoradiation resistance in oesophageal cancer cells via the PSEN1 gene. target gene hsa-mir-320 Inflammatory Bowel Diseases 26752466 Exogenous miR-320 transfection in HT29 cells leads to a significant decrease of NOD2 expression target gene hsa-mir-19 Gastric Neoplasms 26762410 "MEF2D is a direct target of miR-19, which was found to be decreased in gastric cancer clinical specimens." target gene hsa-mir-4480 Macular Degeneration 26765636 Functional single nucleotide polymorphism in IL-17A 3' untranslated region is targeted by miR-4480 in vitro and may be associated with age-related macular degeneration. target gene hsa-mir-215 Glioma 26766590 MiR-215 Is Induced Post-transcriptionally via HIF-Drosha Complex and Mediates Glioma-Initiating Cell Adaptation to Hypoxia by Targeting KDM1B. target gene hsa-mir-328 "Carcinoma, Esophageal" 26773497 MiR-328 suppresses the survival of esophageal cancer cells by targeting PLCE1. target gene hsa-mir-367 "Squamous Cell Carcinoma, Esophageal" 26777997 MiR-367 is a potential biomarker for ESCC and may act as an oncogene in regulating ESCC development. target gene hsa-mir-155 Ovarian Neoplasms 26779627 miR-155 mediates cisplatin-induced apoptosis by targeting XIAP in ovarian cancer target gene hsa-mir-205 "Aortic Aneurysm, Abdominal" 26781079 a significant downregulation of LRP1 protein expression was shown in miR-205-overexpressing VSMCs target gene hsa-mir-96 Cardiomegaly 26782545 miR-96 inhibits cardiac hypertrophy by targeting growth factor receptor-bound 2. target gene hsa-mir-141 "Carcinoma, Hepatocellular" 26790956 MiR-141 suppression may cause aberrant expression of SPAG9 and promote HCC tumorigenesis via JNK pathway. target gene hsa-mir-148a Lupus Nephritis 26791485 miR-148a-3p overexpression contributes to glomerular cell proliferation by targeting PTEN in lupus nephritis. target gene hsa-mir-200a "Carcinoma, Renal Cell" 26797273 MicroRNA-200a-3p suppresses tumor proliferation and induces apoptosis by targeting SPAG9 in renal cell carcinoma. target gene hsa-mir-31 Glioma 26801671 the suppressive effect of miR-31 on glioma cell migration and invasion is p21-dependent target gene hsa-mir-29a "Carcinoma, Breast" 26802653 "inhibitors of microRNA-29a promote apoptosis through upregulation of HSP60 level and downregulation of HSP27, HSP40, HSP70, and HSP90 levels" target gene hsa-mir-142 Neoplasms [unspecific] 26805039 Our observations suggest that miR-142-3p functioned as a tumor suppressor by targeting CDC25C. target gene hsa-mir-625 Breast Neoplasms 26806308 miR-625 suppresses cell proliferation and migration by targeting HMGA1 in breast cancer. target gene hsa-mir-143 "Squamous Cell Carcinoma, Esophageal" 26806810 MiR-143 inhibits tumor cell proliferation and invasion by targeting STAT3 in esophageal squamous cell carcinoma. target gene hsa-mir-34c Prostate Neoplasms 26808578 Functional analysis revealed that miR-34c and miR-297 overexpression down-regulated AR expression and inhibited the expression of downstream AR targets target gene hsa-mir-21 Colorectal Carcinoma 26811607 "MicroRNA-21 increases the levels of IL-10 and prostaglandin E2, which suppress antitumor T-cell-mediated adaptive immunity" target gene hsa-mir-133a Dengue Virus Infection 26818704 miRNA-133a regulates DENV replication possibly through the modulation of a host factor such as PTB. Further investigations are needed to verify whether miRNA-133a has an anti-DENV effect in vivo. target gene hsa-mir-33a Japanese Encephalitis Virus Infection 26819305 MicroRNA-33a-5p Modulates Japanese Encephalitis Virus Replication by Targeting Eukaryotic Translation Elongation Factor 1A1. target gene hsa-mir-519 Gastric Neoplasms 26819420 MiR-may inhibit the gastric cancer cell activity through suppression of HuR expression. target gene hsa-mir-187 Colorectal Carcinoma 26820227 "MicroRNA-187, a downstream effector of TGF¦Â pathway, suppresses Smad-mediated epithelial-mesenchymal transition in colorectal cancer." target gene hsa-mir-142 Fever 26825461 "RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever." target gene hsa-mir-143 Fever 26825461 "RBM3 regulates temperature sensitive miR-142-5p and miR-143 (thermomiRs), which target immune genes and control fever." target gene hsa-mir-26b "Carcinoma, Lung, Non-Small-Cell" 26827826 MicroRNA-26b suppresses the metastasis of non-small cell lung cancer by targeting MIEN1 via NF-¦ÊB/MMP-9/VEGF pathways. target gene hsa-mir-489 Breast Neoplasms 26828271 GSE1 negative regulation by miR-489-5p promotes breast cancer cell proliferation and invasion. target gene hsa-mir-20a Breast Neoplasms 26829385 MiR-20a and miR-20b negatively regulate autophagy by targeting RB1CC1/FIP200 in breast cancer cells. target gene hsa-mir-20b Breast Neoplasms 26829385 MiR-20a and miR-20b negatively regulate autophagy by targeting RB1CC1/FIP200 in breast cancer cells. target gene hsa-mir-205 Neoplasms [unspecific] 26831618 "This alteration inverts relative expression levels of ZEB1 and its antagonizing microRNAs, miR-205 and miR-200c" target gene hsa-mir-7 "Carcinoma, Hepatocellular" 26831666 miR-7 suppressed the expression of VDAC1 target gene hsa-mir-505 "Carcinoma, Endometrial" 26832151 "Taken together, this study demonstrates that miR-505 acts as tumor suppressor in EC by regulating TGF-¦Á." target gene hsa-mir-103 Atherosclerosis 26837267 Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4. target gene hsa-mir-497 Colorectal Carcinoma 26840372 Thus our results provide evidence that miR-497 might function as a metastasis suppressor in CRC. Targeting miR-497 may provide a strategy for blocking its metastasis. target gene hsa-mir-302a Breast Neoplasms 26842910 Our results indicate that miR-302 cooperatively sensitizes breast cancer cells to adriamycin via suppressing P-glycoprotein by targeting MEKK1 of ERK pathway. miR-302 gene cluster may be a potential target for reversing P-gp-mediated chemoresistance in breast cancer. target gene hsa-mir-302b Breast Neoplasms 26842910 Our results indicate that miR-302 cooperatively sensitizes breast cancer cells to adriamycin via suppressing P-glycoprotein by targeting MEKK1 of ERK pathway. miR-302 gene cluster may be a potential target for reversing P-gp-mediated chemoresistance in breast cancer. target gene hsa-mir-302c Breast Neoplasms 26842910 Our results indicate that miR-302 cooperatively sensitizes breast cancer cells to adriamycin via suppressing P-glycoprotein by targeting MEKK1 of ERK pathway. miR-302 gene cluster may be a potential target for reversing P-gp-mediated chemoresistance in breast cancer. target gene hsa-mir-302d Breast Neoplasms 26842910 Our results indicate that miR-302 cooperatively sensitizes breast cancer cells to adriamycin via suppressing P-glycoprotein by targeting MEKK1 of ERK pathway. miR-302 gene cluster may be a potential target for reversing P-gp-mediated chemoresistance in breast cancer. target gene hsa-mir-26b "Carcinoma, Hepatocellular" 26843134 MicroRNA-26b Enhances the Radiosensitivity of Hepatocellular Carcinoma Cells by Targeting EphA2. target gene hsa-let-7 Myocardial Ischemic-Reperfusion Injury 26844226 "After Myocardial Ischemia-Reperfusion, miR-29a, and Let7 Could Affect Apoptosis through Regulating IGF-1." target gene hsa-mir-15a Myasthenia Gravis 26845678 MiR-15a contributes abnormal immune response in myasthenia gravis by targeting CXCL10. target gene hsa-mir-182 "Adenocarcinoma, Endometrial" 26847831 miR-182 expression is epigenetically increased leading to decreased CUL5 expression and increased cellular proliferation. target gene hsa-mir-34a Colon Neoplasms 26849305 miR-34a directly suppresses Numb in early-stage colon cancer stem cells (CCSCs) target gene hsa-mir-873 Ovarian Neoplasms 26850595 overexpression of miR-873 increased the sensitivity of ovarian cancer cells to cisplatin and paclitaxel by targeting MDR1 expression. target gene hsa-mir-320a Ischemia-Reperfusion Injury 26850728 intrathecal infusion of miR-320a mimic attenuated IR-induced lower limb motor function deficits target gene hsa-mir-1 "Carcinoma, Nasopharyngeal" 26852690 "miR-1, regulated by LMP1, suppresses tumour growth and metastasis by targeting K-ras in nasopharyngeal carcinoma." target gene hsa-mir-504 Glioma 26854715 "A tumor-suppressive microRNA, miR-504, inhibits cell proliferation and promotes apoptosis by targeting FOXP1 in human glioma." target gene hsa-mir-26a Osteoarthritis 26854724 MicroRNA-26a-5p regulates the expression of inducible nitric oxide synthase via activation of NF-¦ÊB pathway in human osteoarthritis chondrocytes. target gene hsa-mir-133b Glioblastoma 26857280 "several miRNAs (miR-133b, miR-30b-3p, miR-145-5p, and miR-146a-5p) targeting EGFR" target gene hsa-mir-145 Glioblastoma 26857280 "several miRNAs (miR-133b, miR-30b-3p, miR-145-5p, and miR-146a-5p) targeting EGFR" target gene hsa-mir-146a Glioblastoma 26857280 "several miRNAs (miR-133b, miR-30b-3p, miR-145-5p, and miR-146a-5p) targeting EGFR" target gene hsa-mir-193b Glioblastoma 26857280 "microRNAs (miRNAs) (miR-193b-3p, miR-518b, miR-520f-3p, and miR-506-5p) targeting PDGFRB were downregulated" target gene hsa-mir-30b Glioblastoma 26857280 "miRNAs (miR-133b, miR-30b-3p, miR-145-5p, and miR-146a-5p) targeting EGFR" target gene hsa-mir-506 Glioblastoma 26857280 "microRNAs (miRNAs) (miR-193b-3p, miR-518b, miR-520f-3p, and miR-506-5p) targeting PDGFRB were downregulated" target gene hsa-mir-518b Glioblastoma 26857280 "microRNAs (miRNAs) (miR-193b-3p, miR-518b, miR-520f-3p, and miR-506-5p) targeting PDGFRB were downregulated" target gene hsa-mir-520f Glioblastoma 26857280 "microRNAs (miRNAs) (miR-193b-3p, miR-518b, miR-520f-3p, and miR-506-5p) targeting PDGFRB were downregulated" target gene hsa-mir-17 Diabetes Mellitus 26858253 "In fact, miR-17 knockdown was able to mimic the IFNγ effects on TXNIP, whereas miR-17 overexpression blunted the cytokine effect." target gene hsa-mir-146 "Carcinoma, Renal Cell" 26859141 "We identified novel target genes of dysregulated miRNAs, which are involved in the transition from primary RCC without metastases into tumors generating distant metastasis." target gene hsa-mir-208a Myocardial Infarction 26861724 miR-208a can promote Ang II-induced cardiomyocyte apoptosis via negatively regulating NLK expression target gene hsa-mir-92a "Carcinoma, Rectal" 26865277 Integrated genomic profiling identifies microRNA-92a regulation of IQGAP2 in locally advanced rectal cancer. target gene hsa-mir-124 Viral Infectious Disease 26865716 "Our data show that microRNA targeting can be used to further increase the safety of an attenuated mengovirus, providing a basis for its development as an oncolytic platform." target gene hsa-mir-125 Viral Infectious Disease 26865716 "Our data show that microRNA targeting can be used to further increase the safety of an attenuated mengovirus, providing a basis for its development as an oncolytic platform." target gene hsa-mir-133 Viral Infectious Disease 26865716 "Our data show that microRNA targeting can be used to further increase the safety of an attenuated mengovirus, providing a basis for its development as an oncolytic platform." target gene hsa-mir-142 Viral Infectious Disease 26865716 "Our data show that microRNA targeting can be used to further increase the safety of an attenuated mengovirus, providing a basis for its development as an oncolytic platform." target gene hsa-mir-208 Viral Infectious Disease 26865716 "Our data show that microRNA targeting can be used to further increase the safety of an attenuated mengovirus, providing a basis for its development as an oncolytic platform." target gene hsa-mir-499 Oral Neoplasms 26867589 This study describes the regulation of PDCD4 specifically in tonsil SCC by miR-499 and miR-21 and has documented the loss of PDCD4 in tonsil SCCs.These findings highlight the complex interplay between miRNAs and tumour suppressor gene regulation and suggest that PDCD4 loss may be an important step in tonsillar carcinogenesis. target gene hsa-mir-486 Ovarian Neoplasms 26871282 "OLFM4 is downregulated by miR-486-5p, which contributes to ovarian cancer tumorigenesis." target gene hsa-mir-23b Ovarian Neoplasms 26872615 Our findings show that miR-23b may inhibit ovarian cancer tumorigenesis and progression by downregulating CCNG1 and the expression of the relevant genes. MiR-23b is a potentially novel application for regulating ovarian carcinoma progression. target gene hsa-mir-130b Colorectal Carcinoma 26873488 colorectal cancer target gene hsa-mir-206 Breast Neoplasms 26879016 significantly negative correlation between miR-206 and Cx43 expression target gene hsa-mir-503 Nephrotic Syndrome 26882816 "In this study, we determined that serum miR-503 was significantly decreased in NS children. MiR-503 contributes to the aberrant proliferation of RMCs by targeting cyclin E, which may represent potential diagnostic and prognostic biomarkers for idiopathic pediatric NS." target gene hsa-mir-195 "Squamous Cell Carcinoma, Tongue" 26885901 Relationships between microRNA expressions and prognosis in patients with tongue squamous cell carcinoma and the mechanisms microRNA regulating tongue squamous cell carcinoma biological behavior. target gene hsa-mir-26a "Squamous Cell Carcinoma, Tongue" 26885901 Relationships between microRNA expressions and prognosis in patients with tongue squamous cell carcinoma and the mechanisms microRNA regulating tongue squamous cell carcinoma biological behavior. target gene hsa-mir-29b "Squamous Cell Carcinoma, Tongue" 26885901 Relationships between microRNA expressions and prognosis in patients with tongue squamous cell carcinoma and the mechanisms microRNA regulating tongue squamous cell carcinoma biological behavior. target gene hsa-mir-34a "Squamous Cell Carcinoma, Tongue" 26885901 Relationships between microRNA expressions and prognosis in patients with tongue squamous cell carcinoma and the mechanisms microRNA regulating tongue squamous cell carcinoma biological behavior. target gene hsa-mir-375 "Squamous Cell Carcinoma, Tongue" 26885901 Relationships between microRNA expressions and prognosis in patients with tongue squamous cell carcinoma and the mechanisms microRNA regulating tongue squamous cell carcinoma biological behavior. target gene hsa-mir-199a Atrial Fibrillation 26888839 "miRNAs regulate the occurrence and development of AF. RFA can change the expression of miRNAs in AF patients, which may be important for reversing the electrical and structural remodeling and maintaining sinus rhythm after RFA.miRNAs, such as miR-30b-5p, miR-377-5p and miR-199a-3p/miR-199b-3p etc., might become the target markers for early diagnosis and intervention of AF in future." target gene hsa-mir-199b Atrial Fibrillation 26888839 "miRNAs regulate the occurrence and development of AF. RFA can change the expression of miRNAs in AF patients, which may be important for reversing the electrical and structural remodeling and maintaining sinus rhythm after RFA.miRNAs, such as miR-30b-5p, miR-377-5p and miR-199a-3p/miR-199b-3p etc., might become the target markers for early diagnosis and intervention of AF in future." target gene hsa-mir-30b Atrial Fibrillation 26888839 "miRNAs regulate the occurrence and development of AF. RFA can change the expression of miRNAs in AF patients, which may be important for reversing the electrical and structural remodeling and maintaining sinus rhythm after RFA.miRNAs, such as miR-30b-5p, miR-377-5p and miR-199a-3p/miR-199b-3p etc., might become the target markers for early diagnosis and intervention of AF in future." target gene hsa-mir-377 Atrial Fibrillation 26888839 "miRNAs regulate the occurrence and development of AF. RFA can change the expression of miRNAs in AF patients, which may be important for reversing the electrical and structural remodeling and maintaining sinus rhythm after RFA.miRNAs, such as miR-30b-5p, miR-377-5p and miR-199a-3p/miR-199b-3p etc., might become the target markers for early diagnosis and intervention of AF in future." target gene hsa-mir-122 Sepsis 26889043 These findings demonstrate that host cellular RNA and specific miRNAs are released into the circulation during polymicrobial sepsis and may function as extracellular mediators capable of promoting cfB production and AP activation through specific TLR7 and MyD88 signaling. target gene hsa-mir-145 Sepsis 26889043 These findings demonstrate that host cellular RNA and specific miRNAs are released into the circulation during polymicrobial sepsis and may function as extracellular mediators capable of promoting cfB production and AP activation through specific TLR7 and MyD88 signaling. target gene hsa-mir-146a Sepsis 26889043 These findings demonstrate that host cellular RNA and specific miRNAs are released into the circulation during polymicrobial sepsis and may function as extracellular mediators capable of promoting cfB production and AP activation through specific TLR7 and MyD88 signaling. target gene hsa-mir-210 Sepsis 26889043 These findings demonstrate that host cellular RNA and specific miRNAs are released into the circulation during polymicrobial sepsis and may function as extracellular mediators capable of promoting cfB production and AP activation through specific TLR7 and MyD88 signaling. target gene hsa-mir-34a Sepsis 26889043 These findings demonstrate that host cellular RNA and specific miRNAs are released into the circulation during polymicrobial sepsis and may function as extracellular mediators capable of promoting cfB production and AP activation through specific TLR7 and MyD88 signaling. target gene hsa-mir-96 "Carcinoma, Lung, Non-Small-Cell" 26893673 "overexpression of miR-96 in NSCLC cells markedly decreased SAMD9 expression and cisplatin-induced apoptosis, and increased the cisplatin IC50" target gene hsa-mir-451a Breast Neoplasms 26896688 "Over-expression of miR-451a can enhance the sensitivity of breast cancer cells to tamoxifen by regulating 14-3-3¦Æ, estrogen receptor ¦Á, and autophagy." target gene hsa-mir-9 Diabetic Cardiomyopathies 26898797 Inhibition of miR-9 upregulates ELAVL1 expression and activates caspase-1. target gene hsa-mir-34a Breast Neoplasms 26902416 LDHA was a direct target of miR-34a target gene hsa-mir-27a Colorectal Carcinoma 26913609 miR-27a modulates a group of proteins involved in MHC class I cell surface exposure target gene hsa-mir-193a Osteosarcoma 26913720 "MiR-193a-3p and miR-193a-5p suppress the metastasis of human osteosarcoma cells by down-regulating Rab27B and SRR, respectively." target gene hsa-mir-21 Granular Corneal Dystrophy 26915797 "TGF-¦Â regulates TGFBIp expression in corneal fibroblasts via miR-21, miR-181a,and Smad signaling." target gene hsa-mir-30a Breast Neoplasms 26918943 we linked miR-30a to increased expression of claudins target gene hsa-mir-26b Prostate Neoplasms 26920049 MiR-26b inhibits autophagy by targeting ULK2 in prostate cancer cells. target gene hsa-mir-137 Schizophrenia 26925706 MicroRNA-137 (miR-137) is a brain-enriched RNA with a critical role in regulating brain development and in mediating synaptic plasticity. target gene hsa-mir-101 Breast Neoplasms 26927545 miR-101 inhibits the proliferation and migration of breast cancer cells via downregulating the expression of DNA methyltransferase 3a. target gene hsa-mir-1227 Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-1234 Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-1915 Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-2861 Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-30d Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-30e Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-320c Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-371b Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-4270 Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-4739 Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-4778 Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-572 Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-6068 Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-6126 Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-6133 Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-638 Diabetic Nephropathy 26930277 "In conclusion, urinary exosomal miRNA content is altered in type II diabetic patients with DN. Deregulated miR-320c, which might have an impact on the TGF-¦Â-signaling pathway via targeting thrombospondin 1 (TSP-1) shows promise as a novel candidate marker for disease progression in type II DN that should be evaluated in future studies." target gene hsa-mir-200b Cervical Neoplasms 26935796 miRâ€?00b was shown to inhibit the function of RhoE and suppress the EMT of cervical cancer target gene hsa-mir-16 Atherosclerosis 26936421 miRâ€?6 is a direct negative regulator of PDCD4 in atherosclerosis. target gene hsa-mir-19b Japanese Encephalitis Virus Infection 26937036 MicroRNA-19b-3p Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF11. target gene hsa-mir-34a Complex Regional Pain Syndrome 26940669 We show that hsa-miR-34a is a negative regulator of CRHR1; overexpression of hsa-miR-34a in Jurkat cells resulted in reduction of CRH-mediated POMC expression. target gene hsa-mir-1271 Pancreatic Neoplasms 26940738 "miR-1271 inhibits migration, invasion and epithelial-mesenchymal transition by targeting ZEB1 and TWIST1 in pancreatic cancer cells." target gene hsa-mir-34a Sickle Cell Anemia 26940952 "miR-34a promoted cell differentiation supported by increased expression of KLF1, glycophorin A, and the erythropoietin receptor." target gene hsa-mir-200c "Carcinoma, Renal Cell, Clear-Cell" 26941587 "miRNA-200c that could regulate COL5A2 and COL5A3, miRNA-15a that could regulate ATP6V0B and miRNA-155 may play key roles in ccRCC progression." target gene hsa-mir-126 Leishmaniasis 26941729 Development of Th2 type specific immune response can be suppressed by binding of miR-135 and miR-126 miRNAs over the 3'-UTR region of GATA-3 transcription factor of Th2 specific CD4(+) T helper cells. target gene hsa-mir-21 Oral Submucous Fibrosis 26943153 PDGF-BB Enhances the Proliferation of Cells in Human Orbital Fibroblasts by Suppressing PDCD4 Expression Via Up-Regulation of microRNA-21. target gene hsa-mir-379 "Carcinoma, Hepatocellular" 26944318 MicroRNA-379-5p inhibits tumor invasion and metastasis by targeting FAK/AKT signaling in hepatocellular carcinoma. target gene hsa-mir-133b Liver Neoplasms 26945106 miR-133b regulation of CTGF is a novel mechanism critical for the proliferation and migration of HCC cells and OC response. target gene hsa-mir-33a Alcoholic Hepatitis 26945479 The relative expression of miR-33a and miR-144 correlated inversely with ABCA1 but not with ABCG1 protein levels. target gene hsa-let-7c "Carcinoma, Lung, Non-Small-Cell" 26945572 "Also, let-7c directly targeted the 3'-untranslated regions of JMJD1A and EZH2." target gene hsa-mir-183 "Adenocarcinoma, Lung" 26951513 overexpression of miR-183 in CSLCs decreased PTPN4 protein levels while inhibition of miR-183 increased PTPN4 protein levels. target gene hsa-mir-183 Choriocarcinoma 26951513 overexpression of miR-183 in CSLCs decreased PTPN4 protein levels while inhibition of miR-183 increased PTPN4 protein levels. target gene hsa-mir-130b Lung Fibrosis 26953888 miR-130b-3p Modulates Epithelial-Mesenchymal Crosstalk in Lung Fibrosis by Targeting IGF-1. target gene hsa-mir-3162 Asthma 26959414 MiR-3162-3p Is a Novel MicroRNA That Exacerbates Asthma by Regulating ¦Â-Catenin. target gene hsa-mir-30 Pancreatic Neoplasms 26965588 high expression of the miR-30 family modulated by CD133 promotes migratory and invasive abilities in CD133(+) pancreatic cancer cells. target gene hsa-mir-30e "Carcinoma, Hepatocellular" 26966067 MiR-30e suppresses proliferation of hepatoma cells via targeting prolyl 4-hydroxylase subunit alpha-1 (P4HA1) mRNA. target gene hsa-mir-125b Neoplasms [unspecific] 26966351 miR-125b acts as a tumor suppressor in chondrosarcoma cells by the sensitization to doxorubicin through direct targeting the ErbB2-regulated glucose metabolism. target gene hsa-mir-138 "Leukemia, Myeloid, Chronic" 26967056 miR-138 in BCR-ABL tyrosine kinase target gene hsa-mir-17 "Leukemia, Myeloid, Chronic" 26967056 "and miR-17, miR-19a, miR-17-92 cluster with MAPK/ERK proteins." target gene hsa-mir-181a "Leukemia, Myeloid, Chronic" 26967056 "miR-155, miR-181a with SOS proteins;" target gene hsa-mir-19a "Leukemia, Myeloid, Chronic" 26967056 "miR-155, miR-19a, with KRAS proteins; miR-19a with RAF1 protein;" target gene hsa-mir-21 Endomyocardial Fibrosis 26968995 miR-21 specific degradation of Smad7 may decrease the inhibitory feedback regulation of TGF-β1/Smad signaling target gene hsa-mir-198 Osteosarcoma 26970302 MicroRNA-198 inhibited tumorous behaviors of human osteosarcoma through directly targeting ROCK1. target gene hsa-mir-31 Sepsis 26978146 Down-regulation of MicroRNA-31 in CD4+ T Cells Contributes to Immunosuppression in Human Sepsis by Promoting TH2 Skewing. target gene hsa-mir-203 Gastric Neoplasms 26980572 MicroRNA-203 suppresses gastric cancer growth by targeting PIBF1/Akt signaling. target gene hsa-mir-26a "Carcinoma, Renal Cell" 26983694 "two genes promoting metastasis, LOXL2 and PLOD2, were epigenetically regulated by tumor-suppressive microRNAs, miR-26a and miR-26b" target gene hsa-mir-124 Alzheimer Disease 26984601 The activation of EPAC-Rap1 pathway was involved in the inhibition of miR-124 in hippocampus under hypoxia or Aβ insult. target gene hsa-mir-122 Liver Neoplasms 26987776 Differential TGF¦Â pathway targeting by miR-122 in humans and mice affects liver cancer metastasis. target gene hsa-mir-203 Essential Thrombocythemia 26990535 miR-203 and miR-221 regulate SOCS1 and SOCS3 in essential thrombocythemia. target gene hsa-mir-221 Essential Thrombocythemia 26990535 miR-203 and miR-221 regulate SOCS1 and SOCS3 in essential thrombocythemia. target gene hsa-let-7a Hirschsprung Disease 26991540 Our study demonstrates that the miR-24-1*/let-7a*-ARP2/3 complex-RAC isoforms pathway may represent a novel pathogenic mechanism for HSCR. target gene hsa-mir-24 Hirschsprung Disease 26991540 Our study demonstrates that the miR-24-1*/let-7a*-ARP2/3 complex-RAC isoforms pathway may represent a novel pathogenic mechanism for HSCR. target gene hsa-mir-145 Atherosclerosis 26992033 miR-145 modulates the phenotypic switch of VSMCs from a contractile to a proliferative state via KLF5 and MYOCD in atherosclerosis. target gene hsa-mir-409 Osteosarcoma 26992637 MicroRNA-409-3p inhibits osteosarcoma cell migration and invasion by targeting catenin-¦Ä1. target gene hsa-mir-16 Breast Neoplasms 26993770 miR-16 sensitizes breast cancer cells to Taxol through the suppression of IKBKB expression target gene hsa-mir-200a Pterygium 26995143 Up-regulated miR-200a levels were positively correlated with and p53 protein expression target gene hsa-mir-138 Cerebral Ischemia 26998035 The expression of Lcn-2 was inhibited by miR-138 mimics and enhanced by miR-138 inhibitors target gene hsa-mir-27a "Leukemia, Myeloid, Acute" 27013583 "Overexpression of miR-424&27a, by targeting the 3'UTR of PLAG1, enhanced TRAIL sensitivity in AML cells." target gene hsa-mir-26b Psoriasis 27015452 Psoriasis Skin Inflammation-Induced microRNA-26b Targets NCEH1 in Underlying Subcutaneous Adipose Tissue. target gene hsa-mir-138 Osteosarcoma 27019355 MiR-138 Acts as a Tumor Suppressor by Targeting EZH2 and Enhances Cisplatin-Induced Apoptosis in Osteosarcoma Cells. target gene hsa-mir-495 Prostate Neoplasms 27031291 MicroRNA-495 Regulates Migration and Invasion in Prostate Cancer Cells Via Targeting Akt and mTOR Signaling. target gene hsa-mir-181a Breast Neoplasms 27033456 "miR-181a, already demonstrated to inhibit ABCG2 translation, was down-regulated by GNT, explaining translational induction." target gene hsa-mir-140 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 27033573 miR-140-5p affects the migration and invasion of hypopharyngeal carcinoma cells by downregulating ADAM10 expression. target gene hsa-mir-720 "Carcinoma, Breast, Triple Negative" 27039296 miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells. target gene hsa-mir-130a Cervical Neoplasms 27040383 miR-130a accelerates cervical cancer cell proliferation by targeting the phosphatase and tensin homolog on chromosome 10 (PTEN) target gene hsa-mir-192 Neoplasms [unspecific] 27041221 A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer. target gene hsa-mir-143 Atopic Dermatitis 27048505 "The forced expression of microRNA-143 mimic blocked the IL-13-induced downregulation of filaggrin, loricrin, and involucrin in epidermal keratinocytes." target gene hsa-mir-491 "Carcinoma, Hepatocellular" 27053618 "miR-491 inhibits the proliferation, invasion and migration of hepatocellular carcinoma cell via down-regulating TPX2 expression." target gene hsa-mir-181b Osteosarcoma 27063156 microRNA-181b promotes migration and invasion of osteosarcoma cells by targeting N-myc downstream regulated gene 2. target gene hsa-mir-155 Breast Neoplasms 27065318 miR-155 potently suppresses ErbB2 in breast cancer cells. target gene hsa-mir-221 "Carcinoma, Thyroid, Papillary" 27077469 miR-221 exacerbated PTC by downregulating the expression of TIMP3. target gene hsa-mir-192 Choriocarcinoma 27079614 microRNA-192 suppresses the expression of FXR and FXR target genes in vitro and in vivo. target gene hsa-mir-143 Glioblastoma 27081712 "miRâ€?43 inhibited the proliferation, migration and invasion of the glioblastoma cells." target gene hsa-mir-205 Gastric Neoplasms 27082508 "transfection with miRâ€?05, the epithelial marker CDH1 (E‑cadherin) was upregulated, and the mesenchymal markers CDH2 (N‑cadherin) and vimentin were suppressed." target gene hsa-mir-30c Malignant Neoplasms [unspecific] 27085140 "miR-30c-1-3p altered basal and induced expression of cytochrome P450 3A4 (CYP3A4), a prototypical target gene of PXR." target gene hsa-mir-4701 "Leukemia, Myeloid, Chronic" 27088512 miR-4701-5p directly targeted ST3GAL1 to reduce CML cells resistance to multiple chemotherapeutics in vitro and to convert tumor cells from adriamycin resistant to susceptible in vivo of mice. target gene hsa-mir-124 Astrocytoma 27088547 "We showed that the repression of PIM1 in astrocytoma cancer cells by miR-124-3p suppressed proliferation, invasion, and aerobic glycolysis and promoted apoptosis." target gene hsa-mir-3188 "Carcinoma, Nasopharyngeal" 27095304 miR-3188 regulates nasopharyngeal carcinoma proliferation and chemosensitivity through a FOXO1-modulated positive feedback loop with mTOR-p-PI3K/AKT-c-JUN. target gene hsa-mir-144 Thyroid Neoplasms 27099512 "Transcription factor zinc finger E-box-binding homeobox 1 (ZEB1), as one of the key inducers of epithelial-mesenchymal transition, has been reported to be regulated by microRNA-144 and Bcl-2-associated athanogene 3" target gene hsa-mir-206 Breast Neoplasms 27100732 Tbx3 is directly repressed by miR-206 target gene hsa-mir-181b Breast Neoplasms 27102539 miR-181b-3p promotes epithelial-mesenchymal transition in breast cancer cells through Snail stabilization by directly targeting YWHAG. target gene hsa-mir-155 Gastric Neoplasms 27113301 Target research on tumor biology characteristics of mir-155-5p regulation on gastric cancer cell. target gene hsa-mir-200a Diabetes Mellitus 27121251 "Transfection with an miR-200a inhibitor increased Rheb protein levels and enhanced the feedback action on insulin receptor substrate-dependent insulin signaling, whereas transfection with an miR-200a mimic produced the opposite effects." target gene hsa-mir-29b Thyroid Neoplasms 27125250 Functional assays confirmed PATZ1 as a target of miR-29b target gene hsa-mir-126 Diabetes Mellitus 27127202 low miR-126 levels to be associated with markedly increased TF protein and TF-mediated thrombogenicity. target gene hsa-mir-200a "Carcinoma, Gastric" 27144885 "Depleting endogenous Bart9 of SNU-719 induced a surged expression of miR-200a and miR-141, accompanied by decreased proliferative and invasive ability." target gene hsa-mir-204 Pulmonary Hypertension 27149112 miR-204 diminution promotes RUNX2 up-regulation target gene hsa-mir-183 Breast Neoplasms 27155522 "among MTUS1 targeting miRNAs, miR-183-5p was identified to be overexpressed in breast cancer and down-regulated in fibroadenoma tissues." target gene hsa-mir-138 Breast Neoplasms 27155849 Only 8 APOBEC3B targeting miRNAs were observed to regulate the fusion transcript of which miR-34b-3p and miR-138-5p were found to be frequently downregulated in cancers suggesting miRNA-mediated deregulation of APOBEC3A expression in cancer patients harbouring this particular deletion polymorphism. target gene hsa-mir-34b Breast Neoplasms 27155849 Only 8 APOBEC3B targeting miRNAs were observed to regulate the fusion transcript of which miR-34b-3p and miR-138-5p were found to be frequently downregulated in cancers suggesting miRNA-mediated deregulation of APOBEC3A expression in cancer patients harbouring this particular deletion polymorphism. target gene hsa-mir-146a Infection [unspecific] 27156837 The in?vitro study suggested that transfected mmu-miR-146a-5p inhibitor upregulated TNF-¦Á and its target gene Traf6 in microglia following stimulation with A. cantonensis larval antigen. target gene hsa-mir-135b Myxoid Liposarcoma 27157622 "Decreased THBS2 expression by miR-135b increases the total amount of matrix metalloproteinase 2 (MMP2) and influences cellular density and an extracellular matrix structure, thereby resulting in morphological change in tumor." target gene hsa-mir-7 Parkinson Disease 27158385 The altered molecular expressions downstream of Bax and Sirt2 are also involved in miR-7 regulation of the MPP(+)-triggered neuronal apoptosis. target gene hsa-mir-21 "Carcinoma, Basal Cell" 27159391 "Moreover, our results identify a miR21/GRHL3/D3 axis that reduces TH in the tumor microenvironment and has potential to be targeted as a therapeutic approach to BCC." target gene hsa-mir-29 "Carcinoma, Hepatocellular" 27164857 "SETDB1 is a target of miR-29, which is frequently downregulated in human HCCs." target gene hsa-mir-146a Breast Neoplasms 27175941 invasion activity in MDA-MB-231 breast cancer cells could be directly influenced by altering miR-146a expression. target gene hsa-mir-195 Preeclampsia 27176145 miR-195 could directly target and suppress the expression of ActRIIB target gene hsa-mir-143 Cervical Neoplasms 27177038 upregulation of miRâ€?43 expression reduced Bclâ€? expression and increased Bax expression in HeLa cells. target gene hsa-mir-577 "Fatty Liver, Non-Alcoholic" 27179781 "NS5ATP6 regulated the expression of miR-577, which directly targeted and regulated FGF21." target gene hsa-mir-105 Heart Failure 27185878 "miR-155 and miR-105, were found to modulate ANP production in human cardiomyocytes" target gene hsa-mir-105 Hypertension 27185878 "miR-155 and miR-105, were found to modulate ANP production in human cardiomyocytes" target gene hsa-mir-155 Heart Failure 27185878 "miR-155 and miR-105, were found to modulate ANP production in human cardiomyocytes" target gene hsa-mir-155 Hypertension 27185878 "miR-155 and miR-105, were found to modulate ANP production in human cardiomyocytes" target gene hsa-mir-425 Heart Failure 27185878 microRNA 425 (miR-425) was found to regulate ANP production target gene hsa-mir-425 Hypertension 27185878 microRNA 425 (miR-425) was found to regulate ANP production target gene hsa-mir-296 Ovarian Neoplasms 27186401 deregulated miR-296/S100A4 promotes tumor progression target gene hsa-mir-23a "Leukemia, Myeloid, Acute" 27197200 overexpression of miR-23a decreased RKIP mRNA and protein expression target gene hsa-mir-186 Myocardial Infarction 27205869 MicroRNA-186 promotes macrophage lipid accumulation and pro-inflammatory cytokine secretion by targeting cystathionine γ-lyase in THP-1 macrophages. target gene hsa-mir-1 Heart Failure 27213338 miR-1 repressed the expression of gap junction protein α1 (GJA1) in VMC target gene hsa-mir-19b Heart Failure 27213338 "a miR-19b inhibitor increased, while its mimics suppressed the expression of GJA1 in HL-1 cells." target gene hsa-mir-31 "Adenocarcinoma, Lung" 27215092 MiR-31 Functions as a Tumor Suppressor in Lung Adenocarcinoma Mainly by Targeting HuR. target gene hsa-mir-4271 Parkinson Disease 27217159 "hsa-miR-4271 was downregulated, which could influence EFNA3 translation" target gene hsa-mir-21 Cervical Neoplasms 27220494 "MiR-21 overexpression decreases PTEN, increases p-Akt, and subsequently increases HIF-1α expression" target gene hsa-mir-194 Breast Neoplasms 27221739 These findings demonstrate that nucleolin expression is down-regulated by miR-194 and miR-206 and upregulated by HuR target gene hsa-mir-377 "Carcinoma, Hepatocellular" 27222047 IRX3 is a direct target of miR-377 target gene hsa-mir-135b "Carcinoma, Endometrial" 27222184 MiR-135b promotes proliferation of endometrial carcinoma cells by targeting FOXO1. target gene hsa-mir-21 "Carcinoma, Renal Cell" 27222255 miRâ€?1 was able to decrease the expression of CASC2 in 786‑O and A498 cells. target gene hsa-mir-143 "Muscular Dystrophy, Duchenne" 27223470 miRNA-143 as a direct regulator of β-dystrobrevin expression target gene hsa-mir-206 Pancreatic Neoplasms 27233476 "Mechanistically, the Nampt expression was independent of Kras and p16 status, but it was directly regulated by miR-206" target gene hsa-mir-203 "Carcinoma, Lung, Non-Small-Cell" 27237033 Both miR-145 and miR-203 can directly target the 3'-untranslated region (3'-UTR) of SMAD3 target gene hsa-mir-183 Neuroblastoma 27239679 Our results reveal the MCM complex to be a critical and directly regulated node within the miR-183 signaling network in MYCN-amplified neuroblastoma cells. target gene hsa-mir-182 Glioma 27246830 miR-182-5p negatively regulated PCDH8 expression by directly targeting its 3'-untranslated region. target gene hsa-mir-21 "Carcinoma, Hepatocellular" 27261510 "Here, we demonstrated that TNFα stimulation induced transcriptional downregulation of MSH2, a member of the mismatch repair family, via NF-κB-dependent miR-21 expression in hepatocytes." target gene hsa-mir-374a "Carcinoma, Nasopharyngeal" 27270423 miR-374a direct targeting of CCND1 is modulated by tumor suppressor PDCD4 via suppressing pPI3K/pAKT/c-JUN signaling. target gene hsa-mir-375 Prostate Neoplasms 27270433 The transcription factor YAP1 was found to be a direct target of miR-375 in prostate cancer. target gene hsa-mir-17 Colon Neoplasms 27278684 miRâ€?7 overexpression led to the degradation of CYP7B1 mRNA expression in DLD1 cells. target gene hsa-mir-218 Prostate Neoplasms 27278788 ectopic expression of these miRNAs suppressed PCa cell aggressiveness target gene hsa-mir-26a Prostate Neoplasms 27278788 the lysyl oxidase-like 2 (LOXL2) gene was directly controlled by these tumor-suppressive miRNAs target gene hsa-mir-26b Prostate Neoplasms 27278788 the lysyl oxidase-like 2 (LOXL2) gene was directly controlled by these tumor-suppressive miRNAs target gene hsa-mir-29a Prostate Neoplasms 27278788 the lysyl oxidase-like 2 (LOXL2) gene was directly controlled by these tumor-suppressive miRNAs target gene hsa-mir-29b Prostate Neoplasms 27278788 the lysyl oxidase-like 2 (LOXL2) gene was directly controlled by these tumor-suppressive miRNAs target gene hsa-mir-29c Prostate Neoplasms 27278788 the lysyl oxidase-like 2 (LOXL2) gene was directly controlled by these tumor-suppressive miRNAs target gene hsa-mir-23a "Carcinoma, Hepatocellular" 27279136 "the miR-23a mimic downregulated IFNγ-induced IRF-1 protein expression, while the miR-23a inhibitor increased IRF-1." target gene hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 27279345 overexpression of miRâ€?05 suppressed the expression of Smad4 target gene hsa-let-7b Hypertension 27286171 micro-RNA Let-7b in post-transcriptional regulation target gene hsa-mir-381 Tuberculosis 27296666 inhibition of miR-381-3p could reverse suppression of CD1c expression and promote T cell responses against BCG infection. target gene hsa-mir-34a Diabetes Mellitus 27297797 "Subsequent overexpression of miR-34a inhibited Fndc5 expression, whereas blockade of miR-34a increased Fndc5 expression in myoblasts." target gene hsa-mir-122 "Carcinoma, Hepatocellular" 27302319 "miR-122*, the passenger strand of miR-122, regulates the activity of p53 by targeting Mdm2." target gene hsa-mir-183 Leukemia 27307158 FOXP3-induced miR-183 expression reduced β-TrCP mRNA stability and suppressed β-TrCP-mediated Sp1 degradation target gene hsa-mir-200b Osteosarcoma 27307751 "miR-200b inhibits the proliferation, migration, and invasion of osteosarcoma cells, probably via the inhibition of ZEB1 expression." target gene hsa-mir-200c Colorectal Carcinoma 27315529 ZEB1 expression was seen in connection with decreased miR-200c expression target gene hsa-mir-134 Liver Fibrosis 27321552 Dieckol suppresses liver fibrosis via caspase activation and miR134 mediated JNK activation and NF-kB inhibition. target gene hsa-mir-301a Osteosarcoma 27323075 Upregulated microRNA-301a in osteosarcoma promotes tumor progression by targeting CDC14A. target gene hsa-mir-22 Vascular Disease [unspecific] 27325558 "miR-22-3p, had its binding site on the 3' UTR of VASH1 mRNA" target gene hsa-mir-511 Alzheimer Disease 27334923 miR-511 is a functional regulator of FKBP5 and can contribute to neuronal differentiation. target gene hsa-mir-335 "Carcinoma, Lung, Small-Cell" 27336605 miR-335 negatively regulated the MDR of WBP5 by targeting its 3'UTR target gene hsa-mir-330 "Leukemia, Myeloid, Acute" 27341144 miR-330-5p is able to strongly silence TIM-3 expression (98.15% silencing) in HL-60 cell line (p = 0.0001). target gene hsa-mir-128 Breast Neoplasms 27341528 AurkA suppressed the expression of miR-128 target gene hsa-mir-103 Alzheimer Disease 27343180 "miR-103 and miR-107, regulate CDK5R1 expression and affect the levels of p35" target gene hsa-let-7a Breast Neoplasms 27345399 let-7a and let-7b mimics attenuated p62-mediated MYC mRNA stabilization target gene hsa-let-7b Breast Neoplasms 27345399 let-7a and let-7b mimics attenuated p62-mediated MYC mRNA stabilization target gene hsa-mir-21 Anaplastic Astrocytoma 27347075 PTEN and miR-21 have been observed to form feedback loops. target gene hsa-mir-25 Anaplastic Astrocytoma 27347075 "PTEN which is targeted by miR-21 and miR-106b, regulates miR-25 which in turn targets TP53" target gene hsa-mir-21 Colorectal Carcinoma 27350731 PTEN is one of the direct target genes of miR-21. target gene hsa-mir-144 Neurodegenerative Diseases [unspecific] 27370936 the expression of 14-3-3γ was upregulated following transfection with miR-7 and miR-144 mimics. target gene hsa-mir-203 Neurodegenerative Diseases [unspecific] 27370936 miR-203 resulted in a down-regulation of 14-3-3θ transcript target gene hsa-mir-7 Neurodegenerative Diseases [unspecific] 27370936 the expression of 14-3-3γ was upregulated following transfection with miR-7 and miR-144 mimics. target gene hsa-mir-106a Lung Neoplasms 27372519 An inverse correlation of miR-106a and ULK1 expression was seen in lung adenocarcinoma. target gene hsa-mir-155 Preeclampsia 27375191 These miRNAs have previously been linked to PE and are predicted to regulate members of the TGF-β pathway. target gene hsa-mir-26a Preeclampsia 27375191 These miRNAs have previously been linked to PE and are predicted to regulate members of the TGF-β pathway. target gene hsa-mir-204 Diabetes Mellitus 27384111 "Taken together, we have identified PERK as a novel target of miR-204 and show that miR-204 inhibits PERK signaling and increases ER stress-induced cell death, revealing for the first time a link between this miRNA and UPR." target gene hsa-mir-145 Human Papilloma Virus Infection 27386862 KLF4 levels are increased in HPV-positive cells through a post-transcriptional mechanism involving E7-mediated suppression of cellular miR-145 target gene hsa-mir-21 "Carcinoma, Renal Cell" 27388719 "in cells treated with AU-1, transient elevation of miR-34 leads to the downregulation of SIRT1, thereby miR-21 is freed from SIRT1-dependent suppression." target gene hsa-mir-34 "Carcinoma, Renal Cell" 27388719 "in cells treated with AU-1, transient elevation of miR-34 leads to the downregulation of SIRT1, thereby miR-21 is freed from SIRT1-dependent suppression. Then, elevated miR-21 upregulates p21/Cip1 protein, followed by the suppression of miR-34 expression." target gene hsa-mir-99a Atherosclerosis 27403035 MiR-99a inhibited the LPS-induced HUVECs inflammation via inhibition of the mTOR/NF-κB signal. target gene hsa-mir-99a Cardiovascular Diseases [unspecific] 27403035 MiR-99a inhibited the LPS-induced HUVECs inflammation via inhibition of the mTOR/NF-κB signal. target gene hsa-mir-133a Diabetes Mellitus 27411382 "Our results revealed that miR-133a mimic treatment improved the contractility of the diabetic rat's heart concomitant with upregulation of TH, cardiac NE, β-AR, and downregulation of TAT and plasma levels of NE." target gene hsa-mir-145 Cardiovascular Diseases [unspecific] 27412561 miR-145 is involved in the anti-proliferation and anti-inflammation effects of aspirin on VSMCs by inhibiting the expression of CD40. target gene hsa-mir-26a Retinoblastoma 27421000 "Beclin 1 is the target of miR-26a in human RB cell lines Y79 and WERi-RB-1, and miR-26a inhibits the expression of Beclin 1 by reducing its mRNA and protein levels." target gene hsa-mir-20b Diabetic Retinopathy 27421659 "Transfection of miR-20b mimic in high glucose (HG)-treated human retinal endothelial cells (HRECs) increased miR-20b expression and decreased the expression level of VEGF mRNA, while transfection of miR-20b inhibitor in control HRECs reduced the miR-20b expression with a corresponding increase of VEGF mRNA." target gene hsa-mir-1273g Hepatitis C Virus Infection 27423040 "Overexpression of miR-1273g-3p could inhibit translation of PTEN, increase the expression of α-SMA, Col1A1, and reduce apoptosis in HSCs." target gene hsa-mir-1273g Liver Cirrhosis 27423040 "Overexpression of miR-1273g-3p could inhibit translation of PTEN, increase the expression of α-SMA, Col1A1, and reduce apoptosis in HSCs." target gene hsa-mir-696 "Diabetes Mellitus, Type 2" 27432632 "Taken together, our findings demonstrate that miR-696 plays an important role in the development of hepatic gluconeogenesis and insulin resistance through the inhibition of PGC-1α translation in the liver." target gene hsa-mir-29a Focal Segmental Glomerulosclerosis 27460630 We also demonstrated that miR-29a acts as a positive regulator of Wnt/β-catenin signaling in cultured mesangial cells and functions to protect cell apoptosis and fibrosis. target gene hsa-mir-203 "Carcinoma, Cervical" 27466497 "Although preliminary, the expression levels of ΔNp63 mRNA and miR-203 seem to be promising for cervical cancer screening." target gene hsa-mir-23b "Diabetes Mellitus, Type 2" 27467285 Survival of autoreactive T lymphocytes by microRNA-mediated regulation of apoptosis through TRAIL and Fas in type 1 diabetes. target gene hsa-mir-590 "Diabetes Mellitus, Type 2" 27467285 "Transcriptome analysis revealed reduced expression of TRAIL, TRAIL-R2, FAS and FASLG (members of the extrinsic apoptosis pathway) in patient-derived compared with healthy donor-derived T cells. This was mirrored by increased expression of microRNAs predicted to regulate these particular genes, namely miR-98, miR-23b and miR-590-5p." target gene hsa-mir-98 "Diabetes Mellitus, Type 2" 27467285 "Transcriptome analysis revealed reduced expression of TRAIL, TRAIL-R2, FAS and FASLG (members of the extrinsic apoptosis pathway) in patient-derived compared with healthy donor-derived T cells. This was mirrored by increased expression of microRNAs predicted to regulate these particular genes, namely miR-98, miR-23b and miR-590-5p." target gene hsa-mir-124 Breast Neoplasms 27468577 Decreased miR-124-3p Expression Prompted Breast Cancer Cell Progression Mainly by Targeting Beclin-1. target gene hsa-mir-216b "Carcinoma, Hepatocellular" 27474751 Regulation of UGT2B Expression and Activity by miR-216b-5p in Liver Cancer Cell Lines. target gene hsa-mir-21 Choriocarcinoma 27475963 "We find various mechanisms of PTEN protein loss in the different tumour cell populations, including allelic PTEN deletions, gross chromosomal 10 aberrations and altered miR-21 expression." target gene hsa-mir-214 "Carcinoma, Lung" 27494742 miR-214 inhibits lung cancer progression by targeting CPD. target gene hsa-mir-34a Gastric Neoplasms 27497057 "Our NVs-mediated miR-34a delivery system specifically increased endogenous target miR levels, thereby attenuating proliferation and migration of gastric cancer cells by repressing the expression of CD44 with decreased levels of Bcl-2, Oct 3/4 and Nanog genes." target gene hsa-mir-128 Glioblastoma 27507538 We demonstrated that miR-31 and miR-128 can bind to the 3'UTR of PVRL4 and decrease PVRL4 levels while anti-miR-31/128 increase PVRL4 levels suggesting that PVRL4 is miRNA targeted. target gene hsa-mir-6734 "Carcinoma, Colon" 27509128 "Collectively, our results demonstrated that miR-6734 inhibits the growth of colon cancer cells by up-regulating p21 gene expression and subsequent induction of cell cycle arrest and apoptosis, suggesting its role as an important endogenous regulator of cancer cell proliferation and survival." target gene hsa-mir-199a Osteoarthritis 27515563 Transfection of OA chondrocytes with anti-miR-199a-3p significantly enhanced COX-2 expression and PGE2 production (P < 0.001). target gene hsa-mir-9 "Carcinoma, Breast" 27520371 CYP4Z1 3'UTR was the potential target of miR-9. CYP4Z1 3'UTR could inhibit the migration and EMT of breast cancer cells via acting as a ceRNA for E-cadherin. target gene hsa-mir-106b Alzheimer Disease 27520374 miR-106b inhibits A¦Â1-42-induced tau phosphorylation at Tyr18 by targeting Fyn. target gene hsa-mir-216b "Carcinoma, Hepatocellular" 27524242 this study firstly revealed that there is a HIF-2¦Á-MALAT1-miR-216b axis regulating MDR of HCC cells via modulating autophagy. target gene hsa-mir-125a Retinal Degeneration 27527066 "Possibly more than 30 miRNAs interact with Rac1 in retina, targeting both UTRs and coding regions." target gene hsa-mir-142 Retinal Degeneration 27527066 "Possibly more than 30 miRNAs interact with Rac1 in retina, targeting both UTRs and coding regions." target gene hsa-mir-96 Retinal Degeneration 27527066 "Validation of miRNA-target mRNA interactions for miR-1, miR-96/182 and miR-96 targeting Ctbp2, Rac1 and Slc6a9, respectively, was demonstrated in vitro." target gene hsa-mir-155 "Leukemia, Myeloid, Acute" 27530922 "our evidence show that IRF3 overexpression in AML promotes cell growth and survival, and miR-155 is involved, indicating that IRF3 may be a potential new biomarker and therapeutic target for AML." target gene hsa-mir-137 Multiple Myeloma 27531781 The miR137-MITF is an important index in judging the prognosis of multiple myeloma. target gene hsa-mir-144 "Carcinoma, Hepatocellular" 27536132 "MiR-144 suppresses cell proliferation, migration, and invasion in hepatocellular carcinoma by targeting SMAD4." target gene hsa-mir-23a "Carcinoma, Ovarian" 27537390 miR-23a promotes IKK¦Á expression but suppresses ST7L expression to contribute to the malignancy of epithelial ovarian cancer cells. target gene hsa-mir-1283 Vascular Injuries 27537404 miRNA-1283 Regulates the PERK/ATF4 Pathway in Vascular Injury by Targeting ATF4. target gene hsa-mir-22 Coronary Artery Disease 27537567 miR-22 contributes to the pathogenesis of patients with coronary artery disease by targeting MCP-1: An observational study. target gene hsa-mir-24 "Carcinoma, Nasopharyngeal" 27538493 Exosomal miR-24-3p impedes T-cell function by targeting FGF11 and serves as a potential prognostic biomarker for nasopharyngeal carcinoma. target gene hsa-mir-98 Alzheimer Disease 27541017 miR-98-5p Acts as a Target for Alzheimer's Disease by Regulating A¦Â Production Through Modulating SNX6 Expression. target gene hsa-mir-146a Juvenile Rheumatoid Arthritis 27541693 MiR-146a modulates macrophage polarization in systemic juvenile idiopathic arthritis by targeting INHBA. target gene hsa-mir-200a "Carcinoma, Hepatocellular" 27542259 Elevated CXCL1 increases hepatocellular carcinoma aggressiveness and is inhibited by miRNA-200a. target gene hsa-mir-203 "Carcinoma, Gastric" 27542403 MiR-203 inhibits tumor invasion and metastasis in gastric cancer by ATM. target gene hsa-mir-154 "Cardiomyopathy, Ischemic" 27542661 MiR-154 directly suppresses DKK2 to activate Wnt signaling pathway and enhance activation of cardiac fibroblasts. target gene hsa-mir-384 "Carcinoma, Hepatocellular" 27542674 MiR-384 regulated IRS1 expression and suppressed cell proliferation of human hepatocellular carcinoma. target gene hsa-mir-100 IgA Nephropathy 27542871 MiR-100-3p and miR-877-3p regulate overproduction of IL-8 and IL-1¦Â in mesangial cells activated by secretory IgA from IgA nephropathy patients. target gene hsa-mir-877 IgA Nephropathy 27542871 MiR-100-3p and miR-877-3p regulate overproduction of IL-8 and IL-1¦Â in mesangial cells activated by secretory IgA from IgA nephropathy patients. target gene hsa-mir-29a Glioma 27543358 Long non-coding RNA H19 regulates glioma angiogenesis and the biological behavior of glioma-associated endothelial cells by inhibiting microRNA-29a. target gene hsa-mir-187 "Carcinoma, Hepatocellular" 27544906 miR-187-3p inhibits the metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting S100A4. target gene hsa-mir-613 Alzheimer Disease 27545218 MicroRNA-613 regulates the expression of brain-derived neurotrophic factor in Alzheimer's disease. target gene hsa-mir-21 Cardiovascular Diseases [unspecific] 27545313 Viral Vector-Based Targeting of miR-21 in Cardiac Nonmyocyte Cells Reduces Pathologic Remodeling of the Heart. target gene hsa-mir-200b Glioma 27545608 MicroRNA-200b-3p suppresses epithelial-mesenchymal transition and inhibits tumor growth of glioma through down-regulation of ERK5. target gene hsa-mir-331 "Carcinoma, Cervical" 27548144 MicroRNA-331-3p Suppresses Cervical Cancer Cell Proliferation and E6/E7 Expression by Targeting NRP2. target gene hsa-mir-29a "Carcinoma, Colon" 27548517 MiR-29a Regulates Radiosensitivity in Human Intestinal Cells by Targeting PTEN Gene. target gene hsa-mir-297 "Adenocarcinoma, Lung" 27554041 miR-297 acts as an oncogene by targeting GPC5 in lung adenocarcinoma. target gene hsa-mir-33b "Carcinoma, Lung" 27559850 DNA damage responsive miR-33b-3p promoted lung cancer cells survival and cisplatin resistance by targeting p21WAF1/CIP1. target gene hsa-mir-138 "Carcinoma, Prostate" 27562865 MiR-26a and miR-138 block the G1/S transition by targeting the cell cycle regulating network in prostate cancer cells. target gene hsa-mir-26a "Carcinoma, Prostate" 27562865 MiR-26a and miR-138 block the G1/S transition by targeting the cell cycle regulating network in prostate cancer cells. target gene hsa-mir-106a "Cardiomyopathy, Hypertrophic" 27565029 miR-106a promotes cardiac hypertrophy by targeting mitofusin 2. target gene hsa-mir-124 "Carcinoma, Cervical" 27571703 "MicroRNA-124 inhibits proliferation, invasion, migration and epithelial-mesenchymal transition of cervical carcinoma cells by targeting astrocyte-elevated gene-1." target gene hsa-mir-127 "Carcinoma, Ovarian" 27571744 MicroRNA-127-3p acts as a tumor suppressor in epithelial ovarian cancer by regulating the BAG5 gene. target gene hsa-mir-451 "Carcinoma, Bladder" 27571748 miR-451 suppresses bladder cancer cell migration and invasion via directly targeting c-Myc. target gene hsa-mir-21 "Carcinoma, Hepatocellular" 27571873 HBx-induced miR-21 suppresses cell apoptosis in hepatocellular carcinoma by targeting interleukin-12. target gene hsa-mir-588 "Squamous Cell Carcinoma, Lung" 27571908 MicroRNA-588 suppresses tumor cell migration and invasion by targeting GRN in lung squamous cell carcinoma. target gene hsa-mir-145 Colorectal Carcinoma 27572146 miR-145 suppresses colorectal cancer cell migration and invasion by targeting an ETS-related gene. target gene hsa-mir-181d "Squamous Cell Carcinoma, Esophageal" 27572270 MicroRNA-181d is a tumor suppressor in human esophageal squamous cell carcinoma inversely regulating Derlin-1. target gene hsa-mir-411 "Carcinoma, Breast" 27572271 miRNA-411 acts as a potential tumor suppressor miRNA via the downregulation of specificity protein 1 in breast cancer. target gene hsa-mir-19b "Carcinoma, Gastric" 27572553 MicroRNA-19b inhibits proliferation of gastric cancer cells by targeting B-cell CLL/lymphoma 3. target gene hsa-mir-15a Human Papilloma Virus Infection 27573302 miR-15a induces cell apoptosis by targeting BCL2L2 and BCL2 in HPV-positive hypopharyngeal squamous cell carcinoma. target gene hsa-mir-23b "Squamous Cell Carcinoma, Oral" 27573718 The tumor-suppressive microRNA-23b/27b cluster regulates the MET oncogene in oral squamous cell carcinoma. target gene hsa-mir-27b "Squamous Cell Carcinoma, Oral" 27573718 The tumor-suppressive microRNA-23b/27b cluster regulates the MET oncogene in oral squamous cell carcinoma. target gene hsa-mir-328 Inflammation 27573788 UPF1 regulates myeloid cell functions and S100A9 expression by the hnRNP E2/miRNA-328 balance. target gene hsa-mir-195 "Carcinoma, Hepatocellular" 27574422 Aptamer-functionalized peptide H3CR5C as a novel nanovehicle for codelivery of fasudil and miRNA-195 targeting hepatocellular carcinoma. target gene hsa-mir-491 Hypercholesterolaemia 27575876 Atorvastatin attenuation of ABCB1 expression is mediated by microRNA miR-491-3p in Caco-2 cells. target gene hsa-mir-30a Colorectal Carcinoma 27576787 MiR-30a-5p Suppresses Tumor Metastasis of Human Colorectal Cancer by Targeting ITGB3. target gene hsa-mir-216 Bladder Neoplasms 27578985 MiR-126 regulates proliferation and invasion in the bladder cancer BLS cell line by targeting the PIK3R2-mediated PI3K/Akt signaling pathway. target gene hsa-mir-19a "Squamous Cell Carcinoma, Oral" 27581787 Micronome revealed miR-19a/b as key regulator of SOCS3 during cancer related inflammation of oral squamous cell carcinoma. target gene hsa-mir-19b "Squamous Cell Carcinoma, Oral" 27581787 Micronome revealed miR-19a/b as key regulator of SOCS3 during cancer related inflammation of oral squamous cell carcinoma. target gene hsa-mir-421 "Carcinoma, Breast" 27583980 MicroRNA-421 inhibits breast cancer metastasis by targeting metastasis associated 1. target gene hsa-mir-7 Intervertebral Disc Degeneration 27583982 MicroRNA-7 regulates IL-1¦Â-induced extracellular matrix degeneration by targeting GDF5 in human nucleus pulposus cells. target gene hsa-mir-98 Osteoarthritis 27590063 MiR-98 promotes chondrocyte apoptosis by decreasing Bcl-2 expression in a rat model of osteoarthritis. target gene hsa-mir-125b Heart Failure 27592695 MiR-125b regulates SFRP5 expression to promote growth and activation of cardiac fibroblasts. target gene hsa-mir-31 "Carcinoma, Breast, Triple Negative" 27593563 MiR-31 inhibits migration and invasion by targeting SATB2 in triple negative breast cancer. target gene hsa-mir-27a Prostate Neoplasms 27594411 Androgen-induced miR-27A acted as a tumor suppressor by targeting MAP2K4 and mediated prostate cancer progression. target gene hsa-mir-15a "Carcinoma, Breast" 27596816 miR-15a/miR-16 induces mitochondrial dependent apoptosis in breast cancer cells by suppressing oncogene BMI1. target gene hsa-mir-16 "Carcinoma, Breast" 27596816 miR-15a/miR-16 induces mitochondrial dependent apoptosis in breast cancer cells by suppressing oncogene BMI1. target gene hsa-mir-141 "Carcinoma, Breast" 27596953 p16INK4A induces senescence and inhibits EMT through microRNA-141/microRNA-146b-5p-dependent repression of AUF1. target gene hsa-mir-146b "Carcinoma, Breast" 27596953 p16INK4A induces senescence and inhibits EMT through microRNA-141/microRNA-146b-5p-dependent repression of AUF1. target gene hsa-mir-15a Myeloma 27596960 "MiR-15a/16 regulates the growth of myeloma cells, angiogenesis and antitumor immunity by inhibiting Bcl-2, VEGF-A and IL-17 expression in multiple myeloma." target gene hsa-mir-16 Myeloma 27596960 "MiR-15a/16 regulates the growth of myeloma cells, angiogenesis and antitumor immunity by inhibiting Bcl-2, VEGF-A and IL-17 expression in multiple myeloma." target gene hsa-mir-199a "Carcinoma, Hepatocellular" 27599545 Anti-invasion and anti-migration effects of miR-199a-3p in hepatocellular carcinoma are due in part to targeting CD151. target gene hsa-mir-3666 "Carcinoma, Lung, Non-Small-Cell" 27599551 MicroRNA-3666-induced suppression of SIRT7 inhibits the growth of non-small cell lung cancer cells. target gene hsa-mir-181a Osteosarcoma 27600004 miR-181a promotes the proliferation and metastasis of osteosarcoma cells by targeting RASSF1A. target gene hsa-mir-150 "Leukemia, Myeloid, Acute" 27601730 AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB. target gene hsa-mir-155 "Leukemia, Myeloid, Acute" 27601730 AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB. target gene hsa-mir-23a "Carcinoma, Endometrioid Endometrial" 27601936 MicroRNA-23a regulates epithelial-to-mesenchymal transition in endometrial endometrioid adenocarcinoma by targeting SMAD3. target gene hsa-mir-19b Breast Neoplasms 27602768 MiR-19b suppresses PTPRG to promote breast tumorigenesis. target gene hsa-mir-9 Knee Osteoarthritis 27603333 MicroRNA-9 regulates the development of knee osteoarthritis through the NF-kappaB1 pathway in chondrocytes. target gene hsa-mir-139 Leukemia 27605510 MicroRNA-139-5p regulates proliferation of hematopoietic progenitors and is repressed during BCR-ABL-mediated leukemogenesis. target gene hsa-mir-15a Endometriosis 27608888 miRNA-15a-5p regulates VEGFA in endometrial mesenchymal stem cells and contributes to the pathogenesis of endometriosis. target gene hsa-mir-141 Glioma 27608897 MiR-200c and miR-141 inhibit ZEB1 synergistically and suppress glioma cell growth and migration. target gene hsa-mir-200c Glioma 27608897 MiR-200c and miR-141 inhibit ZEB1 synergistically and suppress glioma cell growth and migration. target gene hsa-mir-135a "Carcinoma, Hepatocellular" 27609066 "HBXIP is able to depress the gluconeogenesis through suppressing PCK1 to promote hepatocarcinogenesis, involving miR-135a/FOXO1 axis and PI3K/Akt/p-FOXO1 pathway" target gene hsa-mir-148a Ischemia-Reperfusion Injury 27609576 The miR-148a alleviates hepatic ischemia/reperfusion injury in mice via targeting CaMKII¦Á. target gene hsa-mir-34a Influenza 27610823 MicroRNA 34a contributes to virus-mediated apoptosis through binding to its target gene Bax in influenza A virus infection. target gene hsa-mir-126 Neoplasms [unspecific] 27611944 MicroRNA-126 inhibits tumor proliferation and angiogenesis of hepatocellular carcinoma by down-regulating EGFL7 expression. target gene hsa-mir-21 Gastric Neoplasms 27611950 MicroRNA-21 promotes TGF-¦Â1-induced epithelial-mesenchymal transition in gastric cancer through up-regulating PTEN expression. target gene hsa-mir-34a "Carcinoma, Oral" 27612478 "miR5423p and miR34a targets the CD44v6-Nanog-PTEN axis, thus playing a vital role in regulating the CSC properties" target gene hsa-mir-542 "Carcinoma, Oral" 27612478 "miR5423p and miR34a targets the CD44v6-Nanog-PTEN axis, thus playing a vital role in regulating the CSC properties" target gene hsa-mir-451 Colorectal Carcinoma 27612504 Expression pattern of miR-451 and its target MIF (macrophage migration inhibitory factor) in colorectal cancer. target gene hsa-mir-1271 "Diabetes Mellitus, Type 2" 27613089 MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells. target gene hsa-mir-26a Neoplasms [unspecific] 27613140 MiR-26a inhibits proliferation and migration of HaCaT keratinocytes through regulating PTEN expression. target gene hsa-mir-223 "Carcinoma, Breast, Triple Negative" 27618431 MicroRNA-223 Increases the Sensitivity of Triple-Negative Breast Cancer Stem Cells to TRAIL-Induced Apoptosis by Targeting HAX-1. target gene hsa-mir-106b "Squamous Cell Carcinoma, Esophageal" 27619676 MiR-106b promotes migration and invasion through enhancing EMT via downregulation of Smad 7 in Kazakh's esophageal squamous cell carcinoma. target gene hsa-mir-214 "Squamous Cell Carcinoma, Esophageal" 27619677 miR-214 inhibits invasion and migration via downregulating GALNT7 in esophageal squamous cell cancer. target gene hsa-mir-346 Preeclampsia 27619846 miR-346 and miR-582-3p-regulated EG-VEGF expression and trophoblast invasion via matrix metalloproteinases 2 and 9. target gene hsa-mir-582 Preeclampsia 27619846 miR-346 and miR-582-3p-regulated EG-VEGF expression and trophoblast invasion via matrix metalloproteinases 2 and 9. target gene hsa-let-7 "Carcinoma, Bladder" 27620744 A let-7 microRNA binding site polymorphism in the KRAS 3'UTR is associated with increased risk and reduced survival for gallbladder cancer in North Indian population. target gene hsa-mir-126 "Carcinoma, Gastric" 27622325 MicroRNA-126 increases chemosensitivity in drug-resistant gastric cancer cells by targeting EZH2. target gene hsa-mir-224 "Carcinoma, Cervical" 27626930 Over-Expressed miR-224 Promotes the Progression of Cervical Cancer via Targeting RASSF8. target gene hsa-mir-4262 "Carcinoma, Breast" 27629257 miR-4262 Promotes Proliferation and Invasion of Human Breast Cancer Cells Through Directly Targeting KLF6 and KLF15. target gene hsa-mir-22 Parkinson Disease 27631550 Neuroprotective Role of MicroRNA-22 in a 6-Hydroxydopamine-Induced Cell Model of Parkinson's Disease via Regulation of Its Target Gene TRPM7. target gene hsa-mir-7 "Carcinoma, Thyroid, Papillary" 27633373 "MicroRNA-7 inhibits proliferation, migration and invasion of thyroid papillary cancer cells via targeting CKS2." target gene hsa-mir-330 "Carcinoma, Colon" 27633518 MicroRNA-330-5p negatively regulates ITGA5 expression in human colorectal cancer. target gene hsa-mir-218 "Squamous Cell Carcinoma, Lung" 27633630 Regulation of TPD52 by antitumor microRNA-218 suppresses cancer cell migration and invasion in lung squamous cell carcinoma. target gene hsa-mir-30c Heart Failure 27633839 MiRNA-30e mediated cardioprotection of ACE2 in rats with Doxorubicin-induced heart failure through inhibiting cardiomyocytes autophagy. target gene hsa-mir-30e Heart Failure 27633839 MiRNA-30e mediated cardioprotection of ACE2 in rats with Doxorubicin-induced heart failure through inhibiting cardiomyocytes autophagy. target gene hsa-let-7g Glioblastoma 27634309 Let-7g-5p inhibits epithelial-mesenchymal transition consistent with reduction of glioma stem cell phenotypes by targeting VSIG4 in glioblastoma. target gene hsa-mir-187 "Carcinoma, Lung" 27634346 MicroRNA?187 is an independent prognostic factor in lung cancer and promotes lung cancer cell invasion via targeting of PTRF. target gene hsa-mir-377 "Carcinoma, Pancreatic" 27638830 MiR-377 inhibits the proliferation of pancreatic cancer by targeting Pim-3. target gene hsa-mir-17 Pulmonary Hypertension 27640178 Upregulated miR-17 Regulates Hypoxia-Mediated Human Pulmonary Artery Smooth Muscle Cell Proliferation and Apoptosis by Targeting Mitofusin 2. target gene hsa-mir-182 Lung Neoplasms 27641336 The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis. target gene hsa-mir-181b Psoriasis 27641447 MicroRNA-181b negatively regulates the proliferation of human epidermal keratinocytes in psoriasis through targeting TLR4. target gene hsa-mir-361 "Carcinoma, Hepatocellular" 27641667 miR-361-5p inhibits hepatocellular carcinoma cell proliferation and invasion by targeting VEGFA. target gene hsa-mir-1304 "Carcinoma, Lung, Non-Small-Cell" 27641735 MicroRNA-1304 suppresses human non-small cell lung cancer cell growth in vitro by targeting heme oxygenase-1. target gene hsa-mir-218 "Carcinoma, Gastric" 27642088 "miR-218 Inhibits Proliferation, Migration, and EMT of Gastric Cancer Cells by Targeting WASF3." target gene hsa-mir-135b "Carcinoma, Lung, Non-Small-Cell" 27643554 miR-135b reverses chemoresistance of non-small cell lung cancer cells by downregulation of FZD1. target gene hsa-mir-185 "Carcinoma, Hepatocellular" 27643556 our findings enlarged our knowledge about the roles of PLAC8 in HCC progression and miR-185-5p/PLAC8/¦Â-catenin axis might be a novel pathway for HCC treatment target gene hsa-mir-141 "Carcinoma, Esophageal" 27644195 Involvement of microRNA-141-3p in 5-fluorouracil and oxaliplatin chemo-resistance in esophageal cancer cells via regulation of PTEN. target gene hsa-mir-124 Osteosarcoma 27644254 The tumor suppressor miR-124 inhibits cell proliferation and invasion by targeting B7-H3 in osteosarcoma. target gene hsa-mir-21 Leukemia 27644439 Bmi-1 regulates stem cell-like properties of gastric cancer cells via modulating miRNAs. target gene hsa-mir-127 "Squamous Cell Carcinoma, Esophageal" 27645894 MicroRNA-127 is a tumor suppressor in human esophageal squamous cell carcinoma through the regulation of oncogene FMNL3. target gene hsa-mir-181b Colorectal Carcinoma 27647131 miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4. target gene hsa-mir-494 "Carcinoma, Colon" 27648301 Targeting the metabolic pathway of human colon cancer overcomes resistance to TRAIL-induced apoptosis. target gene hsa-mir-138 Pulmonary Hypertension 27648837 "MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype." target gene hsa-mir-25 Pulmonary Hypertension 27648837 "MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype." target gene hsa-mir-29 Osteosarcoma 27649654 Targeting miR-29 induces apoptosis of osteosarcoma MG-63 cells via regulation of TGF-¦Â1/PUMA signal. target gene hsa-mir-24 "Carcinoma, Hepatocellular" 27650047 MiR-24-3p enhances cell growth in hepatocellular carcinoma by targeting metallothionein 1M. target gene hsa-mir-185 "Carcinoma, Breast" 27651238 RKIP suppresses the proliferation and metastasis of breast cancer cell lines through up-regulation of miR-185 targeting HMGA2. target gene hsa-mir-30a "Carcinoma, Nasopharyngeal" 27656832 IGF-I Induces Epithelial-to-Mesenchymal Transition via the IGF-IR-Src-MicroRNA-30a-E-Cadherin Pathway in Nasopharyngeal Carcinoma Cells. target gene hsa-mir-124 Melanoma 27657824 Upregulation of miR-124 by physcion 8-O-¦Â-glucopyranoside inhibits proliferation and invasion of malignant melanoma cells via repressing RLIP76. target gene hsa-mir-92b "Squamous Cell Carcinoma, Esophageal" 27659550 "RAB23, regulated by miR-92b, promotes the progression of esophageal squamous cell carcinoma." target gene hsa-mir-33b Osteosarcoma 27662380 MicroRNA-33b Inhibits the Proliferation and Migration of Osteosarcoma Cells via Targeting Hypoxia-Inducible Factor-1¦Á. target gene hsa-mir-199a Liver Cirrhosis 27662798 Fibrogenic Signaling Is Suppressed in Hepatic Stellate Cells through Targeting of Connective Tissue Growth Factor (CCN2) by Cellular or Exosomal MicroRNA-199a-5p. target gene hsa-mir-21 Cardiovascular Diseases [unspecific] 27663503 "DDAH1 3'-UTR as a target for miR-21, and endogenous miR-21 showed increased inhibitory effect on DDAH1-V3 transcript" target gene hsa-mir-215 "Carcinoma, Colon" 27663660 "MicroRNA-215 suppresses cell proliferation, migration and invasion of colon cancer by repressing Yin-Yang 1." target gene hsa-mir-224 "Carcinoma, Ovarian" 27663866 Upregulated microRNA-224 promotes ovarian cancer cell proliferation by targeting KLLN. target gene hsa-mir-463 Diabetes Mellitus 27664094 MicroRNA-463-3p/ABCG4: A new axis in glucose-stimulated insulin secretion. target gene hsa-mir-181a "Carcinoma, Renal Cell" 27664584 microRNAs target SRSF7 splicing factor to modulate the expression of osteopontin splice variants in renal cancer cells. target gene hsa-mir-30a "Carcinoma, Renal Cell" 27664584 microRNAs target SRSF7 splicing factor to modulate the expression of osteopontin splice variants in renal cancer cells. target gene hsa-mir-370 Hepatitis B Virus Infection 27664977 miR-370 suppresses HBV gene expression and replication by targeting nuclear factor IA. target gene hsa-mir-138 "Carcinoma, Lung, Non-Small-Cell" 27665963 MicroRNA-138 inhibits migration and invasion of non-small cell lung cancer cells by targeting LIMK1. target gene hsa-mir-200c "Carcinoma, Lung" 27666124 miR-200c regulates crizotinib-resistant ALK-positive lung cancer cells by reversing epithelial-mesenchymal transition via targeting ZEB1. target gene hsa-let-7a "Squamous Cell Carcinoma, Lung" 27666488 MicroRNAs modulate the expression of the SOX18 transcript in lung squamous cell carcinoma. target gene hsa-mir-24 "Squamous Cell Carcinoma, Lung" 27666488 MicroRNAs modulate the expression of the SOX18 transcript in lung squamous cell carcinoma. target gene hsa-mir-210 "Carcinoma, Hepatocellular" 27666683 MicroRNA-210 promotes cancer angiogenesis by targeting fibroblast growth factor receptor-like?1 in hepatocellular carcinoma. target gene hsa-mir-19a Diabetes Mellitus 27666763 "MicroRNA-19a-3p enhances the proliferation and insulin secretion, while it inhibits the apoptosis of pancreatic ¦Â?cells via the inhibition of SOCS3." target gene hsa-mir-101 "Leukemia, Lymphoblastic, Acute, T-Cell" 27666896 MicroRNA-101 regulates T-cell acute lymphoblastic leukemia progression and chemotherapeutic sensitivity by targeting Notch1. target gene hsa-mir-372 "Carcinoma, Prostate" 27673408 microRNA-372 Suppresses Migration and Invasion by Targeting p65 in Human Prostate Cancer Cells. target gene hsa-mir-122 Chronic Hepatitis C 27677491 microRNA-122 target sites in the hepatitis C virus RNA NS5B coding region and 3' untranslated region: function in replication and influence of RNA secondary structure. target gene hsa-mir-16 "Carcinoma, Gastric" 27683052 Direct targeting of HGF by miR-16 regulates proliferation and migration in gastric cancer. target gene hsa-mir-192 Osteosarcoma 27683056 Upregulation of miR-192 inhibits cell growth and invasion and induces cell apoptosis by targeting TCF7 in human osteosarcoma. target gene hsa-mir-490 "Carcinoma, Lung" 27683057 MicroRNA-490 regulates lung cancer metastasis by targeting poly r(C)-binding protein 1. target gene hsa-mir-204 "Carcinoma, Prostate" 27686228 The UCA1/miR-204/Sirt1 axis modulates docetaxel sensitivity of prostate cancer cells. target gene hsa-mir-451 "Carcinoma, Lung" 27686452 MicroRNA-451 sensitizes lung cancer cells to cisplatin through regulation of Mcl-1. target gene hsa-mir-122 "Carcinoma, Hepatocellular" 27687586 WNT1 Gene from WNT Signaling Pathway Is a Direct Target of miR-122 in Hepatocellular Carcinoma. target gene hsa-mir-483 Cervical Neoplasms 27693430 miR-483 is a self-regulating microRNA and can activate its own expression via USF1 in HeLa cells. target gene hsa-mir-214 "Carcinoma, Breast" 27693451 "Crosstalk between the vitamin D receptor (VDR) and miR-214 in regulating SuFu, a hedgehog pathway inhibitor in breast cancer cells." target gene hsa-mir-939 "Carcinoma, Breast" 27693459 Breast cancer-secreted miR-939 downregulates VE-cadherin and destroys the barrier function of endothelial monolayers. target gene hsa-mir-1207 "Carcinoma, Prostate" 27693493 miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin. target gene hsa-mir-125a "Carcinoma, Breast" 27693788 Enforced expression of hsa-miR-125a-3p in breast cancer cells potentiates docetaxel sensitivity via modulation of BRCA1 signaling. target gene hsa-mir-9 "Carcinoma, Laryngeal" 27694005 Enhanced miR-9 promotes laryngocarcinoma cell survival via down-regulating PTEN. target gene hsa-mir-34a Cardiovascular Diseases [unspecific] 27694688 it could be considered as a circulating biomarker for anthracycline-induced cardiac damage target gene hsa-mir-218 "Carcinoma, Gastric" 27696291 "MicroRNA-218 inhibits the proliferation, migration, and invasion and promotes apoptosis of gastric cancer cells by targeting LASP1." target gene hsa-mir-935 "Carcinoma, Hepatocellular" 27697092 miR-935 Promotes Liver Cancer Cell Proliferation and Migration by Targeting SOX7. target gene hsa-mir-509 "Carcinoma, Gastric" 27697095 MicroRNA-509-3p Inhibits Cancer Cell Proliferation and Migration via Upregulation of XIAP in Gastric Cancer Cells. target gene hsa-mir-1298 Lung Neoplasms 27698189 miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3. target gene hsa-mir-186 Melanoma 27698793 miR-186 suppressed CYLD expression and promoted cell proliferation in human melanoma. target gene hsa-mir-182 "Squamous Cell Carcinoma, Tongue" 27698823 miRNA-335 and miRNA-182 affect the occurrence of tongue squamous cell carcinoma by targeting survivin. target gene hsa-mir-101 "Carcinoma, Hepatocellular" 27702662 Upregulation of SNHG6 regulates ZEB1 expression by competitively binding miR-101-3p and interacting with UPF1 in hepatocellular carcinoma. target gene hsa-mir-34c "Carcinoma, Hepatocellular" 27704267 MicroRNA-34c-3p promotes cell proliferation and invasion in hepatocellular carcinoma by regulation of NCKAP1 expression. target gene hsa-mir-27b "Carcinoma, Hepatocellular" 27704356 MicroRNA-27b exerts an oncogenic function by targeting Fbxw7 in human hepatocellular carcinoma. target gene hsa-mir-491 Osteosarcoma 27704627 Up-regulation of microRNA-491-5p suppresses cell proliferation and promotes apoptosis by targeting FOXP4 in human osteosarcoma. target gene hsa-mir-15a Breast Neoplasms 27713175 Fatty acid synthase is a primary target of MiR-15a and MiR-16-1 in breast cancer. target gene hsa-mir-16 Breast Neoplasms 27713175 Fatty acid synthase is a primary target of MiR-15a and MiR-16-1 in breast cancer. target gene hsa-mir-186 "Carcinoma, Lung, Non-Small-Cell" 27714074 miR-186 regulates chemo-sensitivity to paclitaxel via targeting MAPT in non-small cell lung cancer (NSCLC). target gene hsa-mir-296 "Carcinoma, Hepatocellular" 27714806 miR-296 inhibits proliferation and induces apoptosis by targeting FGFR1 in human hepatocellular carcinoma. target gene hsa-mir-144 "Carcinoma, Renal Cell" 27717821 miR-144-3p serves as a tumor suppressor for renal cell carcinoma and inhibits its invasion and metastasis by targeting MAP3K8. target gene hsa-mir-216b "Carcinoma, Breast" 27720715 miR-216b suppresses breast cancer growth and metastasis by targeting SDCBP. target gene hsa-mir-320 Osteosarcoma 27721258 Inhibitory roles of miR-320 in osteosarcoma via regulating E2F1. target gene hsa-mir-326 Osteosarcoma 27723574 MiR-326 is a diagnostic biomarker and regulates cell survival and apoptosis by targeting Bcl-2 in osteosarcoma. target gene hsa-mir-221 Pancreatic Neoplasms 27726102 MiRNA-221-3p desensitizes pancreatic cancer cells to 5-fluorouracil by targeting RB1. target gene hsa-mir-126 Rheumatoid Arthritis 27729613 MicroRNA-126 affects rheumatoid arthritis synovial fibroblast proliferation and apoptosis by targeting PIK3R2 and regulating PI3K-AKT signal pathway. target gene hsa-mir-133a "Carcinoma, Laryngeal" 27730543 "MicroRNA-133a suppresses the proliferation, migration, and invasion of laryngeal carcinoma cells by targeting CD47." target gene hsa-mir-145 Atherosclerosis 27731400 miRNA-145 inhibits VSMC proliferation by targeting CD40. target gene hsa-mir-139 Epilepsy 27731509 MicroRNA-139-5p negatively regulates NR2A-containing NMDA receptor in the rat pilocarpine model and patients with temporal lobe epilepsy. target gene hsa-mir-203 "Adenocarcinoma, Lung" 27733346 Direct interaction between miR-203 and ZEB2 suppresses epithelial-mesenchymal transition signaling and reduces lung adenocarcinoma chemoresistance. target gene hsa-mir-494 "Carcinoma, Gastric" 27735036 miR-494 inhibits invasion and proliferation of gastric cancer by targeting IGF-1R. target gene hsa-mir-124 "Carcinoma, Lung" 27735038 MicroRNA-124 suppresses Slug-mediated lung cancer metastasis. target gene hsa-mir-132 "Carcinoma, Lung, Non-Small-Cell" 27735039 "MicroRNA-132 inhibits migration, invasion and epithelial-mesenchymal transition by regulating TGF¦Â1/Smad2 in human non-small cell lung cancer." target gene hsa-mir-21 Wound Healing 27735045 microRNA-21 mediates the TGF-¦Â1-induced migration of keratinocytes via targeting PTEN. target gene hsa-mir-590 "Carcinoma, Colon" 27735951 MiR-590-5p inhibits colorectal cancer angiogenesis and metastasis by regulating nuclear factor 90/vascular endothelial growth factor A axis. target gene hsa-mir-105 Glioma 27736002 MicroRNA-105 targets SOX9 and inhibits human glioma cell progression. target gene hsa-mir-149 "Diabetes Mellitus, Type 1" 27737950 "MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic ¦Â-Cells." target gene hsa-mir-23a "Diabetes Mellitus, Type 1" 27737950 "MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic ¦Â-Cells." target gene hsa-mir-23b "Diabetes Mellitus, Type 1" 27737950 "MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic ¦Â-Cells." target gene hsa-mir-183 "Leukemia, Myeloid, Acute, Pediatric" 27738758 MicroRNA-183 promotes cell proliferation via regulating programmed cell death 6 in pediatric acute myeloid leukemia. target gene hsa-mir-585 "Carcinoma, Lung, Non-Small-Cell" 27743168 MicroRNA-585 acts as a tumor suppressor in non-small-cell lung cancer by targeting hSMG-1. target gene hsa-mir-551b "Carcinoma, Ovarian" 27743201 "Downregulation of Foxo3 and TRIM31 by miR-551b in side population promotes cell proliferation, invasion, and drug resistance of ovarian cancer." target gene hsa-mir-124 Osteosarcoma 27743351 MicroRNA-124 upregulation inhibits proliferation and invasion of osteosarcoma cells by targeting sphingosine kinase 1. target gene hsa-mir-25 "Carcinoma, Cervical" 27743413 miR-25-3p reverses epithelial-mesenchymal transition via targeting Sema4C in cisplatin-resistance cervical cancer cells. target gene hsa-mir-96 "Carcinoma, Prostate" 27746161 Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6. target gene hsa-mir-1297 "Carcinoma, Prostate" 27746178 MicroRNA-1297 inhibits prostate cancer cell proliferation and invasion by targeting the AEG-1/Wnt signaling pathway. target gene hsa-mir-155 Idiopathic Pulmonary Fibrosis 27746237 The role of microRNA-155/liver X receptor pathway in experimental and idiopathic pulmonary fibrosis. target gene hsa-mir-16 Recurrent Spontaneous Abortion 27748453 MicroRNA-16 inhibits feto-maternal angiogenesis and causes recurrent spontaneous abortion by targeting vascular endothelial growth factor. target gene hsa-mir-204 "Carcinoma, Hepatocellular" 27748572 miR-204-5p targeting SIRT1 regulates hepatocellular carcinoma progression. target gene hsa-mir-16 Glioma 27748823 "MicroRNA-16 inhibits the proliferation, migration and invasion of glioma cells by targeting Sal-like protein?4." target gene hsa-mir-203 Myeloma 27748826 miR-203 inhibits cell growth and regulates G1/S transition by targeting Bmi-1 in myeloma cells. target gene hsa-mir-382 "Carcinoma, Prostate" 27748848 MicroRNA-382 inhibits prostate cancer cell proliferation and metastasis through targeting COUP-TFII. target gene hsa-mir-455 "Carcinoma, Hepatocellular" 27748890 MicroRNA-455 regulates migration and invasion of human hepatocellular carcinoma by targeting Runx2. target gene hsa-mir-124 "Carcinoma, Breast" 27748910 MicroRNA-124 inhibits cell proliferation and migration by regulating SNAI2 in breast cancer. target gene hsa-mir-20a "Carcinoma, Hepatocellular" 27748919 MicroRNA-20a-5p targets RUNX3 to regulate proliferation and migration of human hepatocellular cancer cells. target gene hsa-mir-520a "Carcinoma, Lung, Non-Small-Cell" 27748920 microRNA-520a-3p inhibits proliferation and cancer stem cell phenotype by targeting HOXD8 in non-small cell lung cancer. target gene hsa-mir-132 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 27751825 MiR-132 plays an oncogenic role in laryngeal squamous cell carcinoma by targeting FOXO1 and activating the PI3K/AKT pathway. target gene hsa-mir-27b Atherosclerosis 27755984 miRNA-27b modulates endothelial cell angiogenesis by directly targeting Naa15 in atherogenesis. target gene hsa-mir-10b "Carcinoma, Hepatocellular" 27756250 miR-10b exerts oncogenic activity in human hepatocellular carcinoma cells by targeting expression of CUB and sushi multiple domains 1 (CSMD1). target gene hsa-mir-302 Neoplasms [unspecific] 27756792 A MicroRNA302-367-Erk1/2-Klf2-S1pr1 Pathway Prevents Tumor Growth via Restricting Angiogenesis and Improving Vascular Stability. target gene hsa-mir-9 Cardiac Fibrosis 27756824 "MicroRNA-9 inhibits high glucose-induced proliferation, differentiation and collagen accumulation of cardiac fibroblasts by down-regulation of TGFBR2." target gene hsa-mir-9 "Fatty Liver, Non-Alcoholic" 27756894 Altered microRNA-9 Expression Level is Directly Correlated with Pathogenesis of Nonalcoholic Fatty Liver Disease by Targeting Onecut2 and SIRT1. target gene hsa-mir-182 Heart Failure 27763637 miR-182 negatively regulated Nogo-C expression and was downregulated during MI target gene hsa-mir-10b Osteosarcoma 27764757 miR-10b promotes invasion by targeting KLF4 in osteosarcoma cells. target gene hsa-mir-451 "Leukemia, Myeloid, Acute" 27764807 c-Myc suppresses miR-451?YWTAZ/AKT axis via recruiting HDAC3 in acute myeloid leukemia. target gene hsa-mir-21 Arteriosclerosis Obliterans 27765464 Cigarette smoking represses expression of cytokine IL-12 and its regulator miR-21-An observational study in patients with coronary artery disease. target gene hsa-mir-29c Idiopathic Pulmonary Fibrosis 27765762 "MicroRNA-29c regulates apoptosis sensitivity via modulation of the cell-surface death receptor, Fas, in lung fibroblasts." target gene hsa-mir-33a "Carcinoma, Gallbladder" 27769047 The microRNA miR-33a suppresses IL-6-induced tumor progression by binding Twist in gallbladder cancer. target gene hsa-mir-16 Chronic Inflammatory Pain 27770129 MicroRNA-16 Alleviates Inflammatory Pain by Targeting Ras-Related Protein 23 (RAB23) and Inhibiting p38 MAPK Activation. target gene hsa-mir-590 "Carcinoma, Lung, Non-Small-Cell" 27770372 microRNA-590 suppresses the tumorigenesis and invasiveness of non-small cell lung cancer cells by targeting ADAM9. target gene hsa-let-7i Neoplasms [unspecific] 27770612 Let-7i-Induced Atg4B Suppression Is Essential for Autophagy of Placental Trophoblast in Preeclampsia. target gene hsa-mir-145 "Squamous Cell Carcinoma, Esophageal" 27771733 MicroRNA-145 Inhibits Cell Migration and Invasion and Regulates Epithelial-Mesenchymal Transition (EMT) by Targeting Connective Tissue Growth Factor (CTGF) in Esophageal Squamous Cell Carcinoma. target gene hsa-mir-218 "Carcinoma, Colon" 27773352 DCC Confers Susceptibility to Depression-like Behaviors in Humans and Mice and Is Regulated by miR-218. target gene hsa-mir-107 "Carcinoma, Hepatocellular" 27773820 MiR-107 suppresses proliferation of hepatoma cells through targeting HMGA2 mRNA 3'UTR. target gene hsa-mir-125b Diabetic Nephropathy 27775793 microRNA-125b contributes to high glucose-induced reactive oxygen species generation and apoptosis in HK-2 renal tubular epithelial cells by targeting angiotensin-converting enzyme 2. target gene hsa-mir-1 Osteosarcoma 27777493 "miR-1 Inhibits Cell Growth, Migration, and Invasion by Targeting VEGFA in Osteosarcoma Cells." target gene hsa-mir-375 "Squamous Cell Carcinoma, Esophageal" 27779648 Regulation of MMP13 by antitumor microRNA-375 markedly inhibits cancer cell migration and invasion in esophageal squamous cell carcinoma. target gene hsa-mir-19a "Carcinoma, Renal Cell, Clear-Cell" 27779660 miR-19a correlates with poor prognosis of clear cell renal cell carcinoma patients via promoting cell proliferation and suppressing PTEN/SMAD4 expression. target gene hsa-mir-4262 Cutaneous Melanoma 27779691 miR-4262 promotes the proliferation of human cutaneous malignant melanoma cells through KLF6-mediated EGFR inactivation and p21 upregulation. target gene hsa-mir-574 "Carcinoma, Prostate" 27779701 Downregulation of microRNA?574 in cancer stem cells causes recurrence of prostate cancer via targeting REL. target gene hsa-mir-300 "Carcinoma, Colon" 27779716 miR-300 promotes proliferation and EMT-mediated colorectal cancer migration and invasion by targeting p53. target gene hsa-mir-148a "Carcinoma, Thyroid" 27779717 miR-148a inhibits self-renewal of thyroid cancer stem cells via repressing INO80 expression. target gene hsa-mir-218 Colorectal Carcinoma 27779719 Downregulation of YEATS4 by miR-218 sensitizes colorectal cancer cells to L-OHP-induced cell apoptosis by inhibiting cytoprotective autophagy. target gene hsa-mir-24 "Carcinoma, Hepatocellular" 27780140 MicroRNA-24 increases hepatocellular carcinoma cell metastasis and invasion by targeting p53: miR-24 targeted p53. target gene hsa-mir-34b Spinal Cord Injuries 27780189 Changes in the Expression of miR-34a and its Target Genes Following Spinal Cord Injury In Rats. target gene hsa-mir-34c Spinal Cord Injuries 27780189 Changes in the Expression of miR-34a and its Target Genes Following Spinal Cord Injury In Rats. target gene hsa-mir-203a "Carcinoma, Hepatocellular" 27780730 miR-203a is involved in HBx-induced inflammation by targeting Rap1a. target gene hsa-mir-379 Osteosarcoma 27781416 MicroRNA-379 suppresses osteosarcoma progression by targeting PDK1. target gene hsa-mir-155 "Leukemia, Myeloid, Acute" 27786352 Targeting miR-155 suppresses proliferation and induces apoptosis of HL-60 cells by targeting Slug/PUMA signal. target gene hsa-mir-101 Glioblastoma 27792996 MicroRNA-101 reverses temozolomide resistance by inhibition of GSK3¦Â in glioblastoma. target gene hsa-mir-637 Pulmonary Hypertension 27794186 Downregulation of microRNA-637 Increases Risk of Hypoxia-Induced Pulmonary Hypertension by Modulating Expression of Cyclin Dependent Kinase 6 (CDK6) in Pulmonary Smooth Muscle Cells. target gene hsa-mir-133a Osteosarcoma 27794430 Down-regulation of RBP-J mediated by microRNA-133a suppresses dendritic cells and functions as a potential tumor suppressor in osteosarcoma. target gene hsa-mir-182 "Carcinoma, Pancreatic" 27797718 MicroRNA-182 promotes pancreatic cancer cell proliferation and migration by targeting ¦Â-TrCP2. target gene hsa-mir-106b "Carcinoma, Lung" 27797825 "MCM7 and its hosted miR-25, 93 and 106b cluster elicit YAP/TAZ oncogenic activity in lung cancer." target gene hsa-mir-25 "Carcinoma, Lung" 27797825 "MCM7 and its hosted miR-25, 93 and 106b cluster elicit YAP/TAZ oncogenic activity in lung cancer." target gene hsa-mir-93 "Carcinoma, Lung" 27797825 "MCM7 and its hosted miR-25, 93 and 106b cluster elicit YAP/TAZ oncogenic activity in lung cancer." target gene hsa-mir-145 Polycystic Ovarian Syndrome 27799458 MicroRNA-145 Negatively Regulates Cell Proliferation Through Targeting IRS1 in Isolated Ovarian Granulosa Cells From Patients With Polycystic Ovary Syndrome. target gene hsa-mir-25 Melanoma 27801786 Upregulated MicroRNA-25 Mediates the Migration of Melanoma Cells by Targeting DKK3 through the WNT/¦Â-Catenin Pathway. target gene hsa-mir-92a Glioma 27801803 miR-92a-3p Exerts Various Effects in Glioma and Glioma Stem-Like Cells Specifically Targeting CDH1/¦Â-Catenin and Notch-1/Akt Signaling Pathways. target gene hsa-mir-133b "Carcinoma, Ovarian" 27802259 Down-Regulation of MicroRNA-133b Suppresses Apoptosis of Lens Epithelial Cell by Up-Regulating BCL2L2 in Age-Related Cataracts. target gene hsa-mir-181a Acute Lung Injury 27802900 Downregulation of miR-181a protects mice from LPS-induced acute lung injury by targeting Bcl-2. target gene hsa-mir-20a Tuberculosis 27803889 microRNA-20a Inhibits Autophagic Process by Targeting ATG7 and ATG16L1 and Favors Mycobacterial Survival in Macrophage Cells. target gene hsa-mir-92a "Lymphoma, Large B-Cell" 27806315 Primary mediastinal large B-cell lymphoma: transcriptional regulation by miR-92a through FOXP1 targeting. target gene hsa-mir-940 "Carcinoma, Hepatocellular" 27807540 miR-940 Suppresses Tumor Cell Invasion and Migration via Regulation of CXCR2 in Hepatocellular Carcinoma. target gene hsa-mir-27b "Carcinoma, Breast" 27809310 Downregulation of microRNA-27b-3p enhances tamoxifen resistance in breast cancer by increasing NR5A2 and CREB1 expression. target gene hsa-mir-222 Ovarian Neoplasms 27811362 MicroRNA-222-3p/GNAI2/AKT axis inhibits epithelial ovarian cancer cell growth and associates with good overall survival. target gene hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 27811366 "MiR-21 and MiR-155 promote non-small cell lung cancer progression by downregulating SOCS1, SOCS6, and PTEN." target gene hsa-mir-214 "Carcinoma, Colon" 27811858 The FOXD3/miR-214/MED19 axis suppresses tumour growth and metastasis in human colorectal cancer. target gene hsa-let-7f Cerebral Ischemia 27812761 Let-7f Regulates the Hypoxic Response in Cerebral Ischemia by Targeting NDRG3. target gene hsa-mir-34a "Carcinoma, Breast" 27813227 MiR-34a modulates ErbB2 in breast cancer. target gene hsa-mir-199a "Carcinoma, Bladder" 27814720 miR-199a-5p suppresses human bladder cancer cell metastasis by targeting CCR7. target gene hsa-mir-542 "Carcinoma, Hepatocellular" 27815069 MicroRNA-542-3p inhibits the growth of hepatocellular carcinoma cells by targeting FZD7/Wnt signaling pathway. target gene hsa-mir-106a Glioblastoma 27815074 MicroRNA-106a-5p facilitates human glioblastoma cell proliferation and invasion by targeting adenomatosis polyposis coli protein. target gene hsa-mir-10a "Lymphoma, Large B-Cell, Diffuse" 27815824 miR-10a inhibits cell proliferation and promotes cell apoptosis by targeting BCL6 in diffuse large B-cell lymphoma. target gene hsa-mir-124 "Carcinoma, Breast" 27815936 MicroRNA-124 enhances response to radiotherapy in human epidermal growth factor receptor 2-positive breast cancer cells by targeting signal transducer and activator of transcription 3. target gene hsa-mir-1 Neoplasms [unspecific] 27819721 miR-1 association with cell proliferation inhibition and apoptosis in vestibular schwannoma by targeting VEGFA. target gene hsa-mir-203 Glioblastoma 27820599 Tissue mechanics promote IDH1-dependent HIF1¦Á-tenascin C feedback to regulate glioblastoma?aggression. target gene hsa-mir-3117 "Carcinoma, Hepatocellular" 27822662 miR-3117 regulates hepatocellular carcinoma cell proliferation by targeting PHLPPL. target gene hsa-mir-143 "Carcinoma, Colon" 27827523 MicroRNA-143 inhibits colorectal cancer cell proliferation by targeting MMP7. target gene hsa-mir-639 "Carcinoma, Thyroid" 27829546 MiR-639 promoted cell proliferation and cell cycle in human thyroid cancer by suppressing CDKN1A expression. target gene hsa-mir-503 Atherosclerosis 27829550 miR-503 inhibits platelet-derived growth factor-induced human aortic vascular smooth muscle cell proliferation and migration through targeting the insulin receptor. target gene hsa-mir-17 "Carcinoma, Breast" 27831559 Decreased expression of microRNA-17 and microRNA-20b promotes breast cancer resistance to taxol therapy by upregulation of NCOA3. target gene hsa-mir-20b "Carcinoma, Breast" 27831559 Decreased expression of microRNA-17 and microRNA-20b promotes breast cancer resistance to taxol therapy by upregulation of NCOA3. target gene hsa-mir-129 "Carcinoma, Breast" 27831649 MiR-129-5p is downregulated in breast cancer cells partly due to promoter H3K27m3 modification and regulates epithelial-mesenchymal transition and multi-drug resistance. target gene hsa-mir-378a Liver Cirrhosis 27832641 Activation of Hepatic Stellate Cells is Inhibited by microRNA-378a-3p via Wnt10a. target gene hsa-mir-146a "Squamous Cell Carcinoma, Esophageal" 27832663 miR-146a-5p mediates epithelial-mesenchymal transition of oesophageal squamous cell carcinoma via targeting Notch2. target gene hsa-mir-199a "Carcinoma, Hepatocellular" 27832779 "miR-199a-3p inhibits cell proliferation and induces apoptosis by targeting YAP1, suppressing Jagged1-Notch signaling in human hepatocellular carcinoma." target gene hsa-mir-375 "Carcinoma, Prostate" 27832783 miR-375 induces docetaxel resistance in prostate cancer by targeting SEC23A and YAP1. target gene hsa-mir-22 Astrocytoma 27834627 Promotion of astrocytoma cell invasion by micro RNA-22 targeting of tissue inhibitor of matrix metalloproteinase-2. target gene hsa-mir-125a Inflammation 27836539 these findings identify a PPAR¦Ã-miR-125a-NOD1 signaling axis in endothelial cells that is critical in the regulation of inflammation-mediated angiogenesis target gene hsa-mir-34a "Carcinoma, Lung" 27836543 miR-34a sensitizes lung cancer cells to cisplatin via p53/miR-34a/MYCN axis. target gene hsa-mir-215 Glioma 27837373 MicroRNA-215 enhances invasion and migration by targeting retinoblastoma tumor suppressor gene 1 in high-grade glioma. target gene hsa-mir-141 "Carcinoma, Lung, Non-Small-Cell" 27840955 miR-141 regulation of EIF4E expression affects docetaxel chemoresistance of non-small cell lung cancer. target gene hsa-mir-503 "Carcinoma, Hepatocellular" 27840964 miR-503 inhibits proliferation making human hepatocellular carcinoma cells susceptible to 5?fluorouracil by targeting EIF4E. target gene hsa-mir-34a Cataract 27840975 miR?34a suppresses proliferation and induces apoptosis of human lens epithelial cells by targeting E2F3. target gene hsa-mir-124 Breast Neoplasms 27842510 miR-124-3p functions as a tumor suppressor in breast cancer by targeting CBL. target gene hsa-mir-148a Multiple Myeloma 27842905 MiR-148a participates in the growth of RPMI8226 multiple myeloma cells by regulating CDKN1B. target gene hsa-mir-27b "Carcinoma, Gastric" 27844448 miR-27b inhibits gastric cancer metastasis by targeting NR2F2. target gene hsa-mir-146a Osteoarthritis 27845876 Hypoxia-induced microRNA-146a represses Bcl-2 through Traf6/IRAK1 but not Smad4 to promote chondrocyte autophagy. target gene hsa-mir-33a "Carcinoma, Lung, Non-Small-Cell" 27856248 MiR-33a suppresses proliferation of NSCLC cells via targeting METTL3 mRNA. target gene hsa-mir-16 Colorectal Carcinoma 27857191 Deregulation of the miR-16-KRAS axis promotes colorectal cancer. target gene hsa-mir-383 "Carcinoma, Lung" 27862077 MicroRNA-383 is a tumor suppressor in human lung cancer by targeting endothelial PAS domain-containing protein 1. target gene hsa-mir-187 "Carcinoma, Gastric" 27864146 MicroRNA-187 regulates gastric cancer progression by targeting the tumor suppressor CRMP1. target gene hsa-mir-335 "Carcinoma, Lung, Small-Cell" 27871924 MiR-335 regulates the chemo-radioresistance of small cell lung cancer cells by targeting PARP-1. target gene hsa-mir-377 "Carcinoma, Lung, Non-Small-Cell" 27874949 miR-377 inhibited tumorous behaviors of non-small cell lung cancer through directly targeting CDK6. target gene hsa-mir-194 "Carcinoma, Gastric" 27874950 miR-194 inhibits gastric cancer cell proliferation and tumorigenesis by targeting KDM5B. target gene hsa-mir-373 "Lymphoma, T-Cell" 27874957 Restoration of microRNA-373 suppresses growth of human T-cell lymphoma cells by repressing CCND1. target gene hsa-mir-137 "Carcinoma, Ovarian" 27875524 microRNA-137 promotes apoptosis in ovarian cancer cells via the regulation of XIAP. target gene hsa-mir-371 Lupus Nephritis 27878241 Hsa?miR?371?5p inhibits human mesangial cell proliferation and promotes apoptosis in lupus nephritis by directly targeting hypoxia?inducible factor 1¦Á. target gene hsa-mir-200b "Carcinoma, Pancreatic" 27878247 Oridonin inhibition and miR?200b?3p/ZEB1 axis in human pancreatic cancer. target gene hsa-mir-362 "Carcinoma, Cervical" 27878258 "MicroRNA-362 is downregulated in cervical cancer and inhibits cell proliferation, migration and invasion by directly targeting SIX1." target gene hsa-mir-3619 "Carcinoma, Prostate" 27878260 miR-3619-5p inhibits prostate cancer cell growth by activating CDKN1A expression. target gene hsa-mir-638 "Carcinoma, Hepatocellular" 27878280 Loss of miR-638 promotes invasion and epithelial-mesenchymal transition by targeting SOX2 in hepatocellular carcinoma. target gene hsa-mir-148a "Carcinoma, Renal Cell" 27878305 miR-148a suppresses human renal cell carcinoma malignancy by targeting AKT2. target gene hsa-mir-429 "Carcinoma, Cervical" 27883176 miR-429 is involved in regulation of NF-¦ÊBactivity by targeting IKK¦Â and suppresses oncogenic activity in cervical cancer cells. target gene hsa-mir-421 "Carcinoma, Cervical" 27886335 microRNA 421 induces apoptosis of c-33a cervical cancer cells via down-regulation of Bcl-xL. target gene hsa-mir-202 "Adenocarcinoma, Lung" 27887846 Long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 regulates the expression of Gli2 by miR-202 to strengthen gastric cancer progression. target gene hsa-mir-136 "Carcinoma, Ovarian" 27887917 MicroRNA-136 inhibits cancer stem cell activity and enhances the anti-tumor effect of paclitaxel against chemoresistant ovarian cancer cells by targeting Notch3. target gene hsa-mir-24 Colon Neoplasms 27888625 "TRIM11, a direct target of miR-24-3p, promotes cell proliferation and inhibits apoptosis in colon cancer." target gene hsa-let-7g Pulmonary Hypertension 27889560 MicroRNA let-7g inhibited hypoxia-induced proliferation of PASMCs via G0/G1 cell cycle arrest by targeting c-myc. target gene hsa-mir-22 "Leukemia, Myeloid, Chronic" 27889568 FosB regulates expression of miR-22 during PMA induced differentiation of K562?cells to megakaryocytes. target gene hsa-mir-181 "Leukemia, T-Cell" 27889686 MicroRNA-181 contributes to downregulation of SAMHD1 expression in CD4+ T-cells derived from S¨¨zary syndrome patients. target gene hsa-mir-146a Dermatomyositis 27889748 MiR-146a Regulates Inflammatory Infiltration by Macrophages in Polymyositis/Dermatomyositis by Targeting TRAF6 and Affecting IL-17/ICAM-1 Pathway. target gene hsa-mir-98 "Carcinoma, Hepatocellular" 27890434 miR-98 inhibits hepatocellular carcinoma cell proliferation via targeting EZH2 and suppressing Wnt/¦Â-catenin signaling pathway. target gene hsa-mir-383 "Carcinoma, Prostate" 27893706 MicroRNA-383 located in frequently deleted chromosomal locus 8p22 regulates CD44 in prostate cancer. target gene hsa-mir-214 Ischemia-Reperfusion Injury 27894079 MicroRNA-214 protects against hypoxia/reoxygenation induced cell damage and myocardial ischemia/reperfusion injury via suppression of PTEN and Bim1 expression. target gene hsa-mir-509 "Carcinoma, Lung, Non-Small-Cell" 27894843 "MiR-509-5p suppresses the proliferation, migration, and invasion of non-small cell lung cancer by targeting YWHAG." target gene hsa-mir-9 Melanoma 27895497 "MicroRNA-9 suppresses the growth, migration, and invasion of malignant melanoma cells via targeting NRP1." target gene hsa-mir-15b Glioblastoma 27896672 miR-15b Inhibits the Progression of Glioblastoma Cells Through Targeting Insulin-like Growth Factor Receptor 1. target gene hsa-mir-26a Prostate Neoplasms 27900011 Downregulated microRNA-26a modulates prostate cancer cell proliferation and apoptosis by targeting COX-2. target gene hsa-mir-150 Osteosarcoma 27900020 MicroRNA-150 upregulation reduces osteosarcoma cell invasion and metastasis by downregulating Ezrin. target gene hsa-mir-138 Cervical Neoplasms 27900047 "MicroRNA-138 inhibits proliferation, migration and invasion through targeting hTERT in cervical cancer." target gene hsa-mir-31 Colitis 27901018 The signaling axis of microRNA-31/interleukin-25 regulates Th1/Th17-mediated inflammation response in colitis. target gene hsa-mir-145 Asthma 27902892 MicroRNA-145 influences the balance of Th1/Th2 via regulating RUNX3 in asthma patients. target gene hsa-mir-125b Myeloma 27903272 "BETi-mediated inhibition of cMYC correlates with the upregulation of miR-125b-5p and the downregulation of the cMYC/miR-125b-5p target gene IRF4, a transcriptional repressor of MICA" target gene hsa-mir-206 Bladder Neoplasms 27904673 MicroRNA-206 acts as a tumor suppressor in bladder cancer via targeting YRDC. target gene hsa-mir-101 "Squamous Cell Carcinoma, Oral" 27904690 miRNA-101 acts as a tumor suppressor in oral squamous cell carcinoma by targeting CX chemokine receptor 7. target gene hsa-mir-491 Glioma 27905892 miR-491 regulates glioma cells proliferation by targeting TRIM28 in vitro. target gene hsa-mir-140 Gout 27906093 microRNA -140-5p inhibits colorectal cancer invasion and metastasis by targeting ADAMTS5 and IGFBP5. target gene hsa-mir-185 "Carcinoma, Lung, Non-Small-Cell" 27906433 MicroRNA-185-5p modulates chemosensitivity of human non-small cell lung cancer to cisplatin via targeting ABCC1. target gene hsa-mir-451 Osteosarcoma 27908732 "miR-451 inhibits cell growth, migration and angiogenesis in human osteosarcoma via down-regulating IL 6R." target gene hsa-mir-146a Vascular Disease [unspecific] 27908889 MicroRNA-146a Induces Lineage-Negative Bone Marrow Cell Apoptosis and Senescence by Targeting Polo-Like Kinase 2 Expression. target gene hsa-mir-101 Glioblastoma 27911279 "MicroRNA-101 inhibits proliferation, migration and invasion of human glioblastoma by targeting SOX9." target gene hsa-mir-346 "Carcinoma, Breast" 27913185 MiR-346 promotes the biological function of breast cancer cells by targeting SRCIN1 and reduces chemosensitivity to docetaxel. target gene hsa-mir-181a Keloid 27915346 MiR-181a Targets PHLPP2 to Augment AKT Signaling and Regulate Proliferation and Apoptosis in Human Keloid Fibroblasts. target gene hsa-mir-21 Lung Fibrosis 27916096 miR-21 promotes pulmonary fibrosis in rats via down-regulating the expression of ADAMTS-1. target gene hsa-mir-217 "Carcinoma, Breast" 27916422 PGC-1 alpha interacts with microRNA-217 to functionally regulate breast cancer cell proliferation. target gene hsa-mir-223 Colorectal Carcinoma 27916606 FBX8 is a metastasis suppressor downstream of miR-223 and targeting mTOR for degradation in colorectal carcinoma. target gene hsa-mir-139 "Carcinoma, Breast" 27916718 Loss of the Opa interacting protein 5 inhibits breast cancer proliferation through miR-139-5p/NOTCH1 pathway. target gene hsa-mir-15a Osteoarthritis 27916780 MiR-15a-5p regulates viability and matrix degradation of human osteoarthritis chondrocytes via targeting VEGFA. target gene hsa-mir-33a "Carcinoma, Prostate" 27921232 Biological function and mechanism of miR-33a in prostate cancer survival and metastasis: via downregulating Engrailed-2. target gene hsa-mir-145 Osteoarthritis 27922673 Effects of miR-145 on the inhibition of chondrocyte proliferation and fibrosis by targeting TNFRSF11B in human osteoarthritis. target gene hsa-mir-152 "Carcinoma, Hepatocellular" 27922690 MicroRNA-152 inhibits tumor cell growth by directly targeting RTKN in hepatocellular carcinoma. target gene hsa-mir-211 "Carcinoma, Cervical" 27923652 MiR-211 inhibits invasion and epithelial-to-mesenchymal transition (EMT) of cervical cancer cells via targeting MUC4. target gene hsa-mir-483 Kawasaki Syndrome 27923814 miR-483 Targeting of CTGF Suppresses Endothelial-to-Mesenchymal Transition: Therapeutic Implications in Kawasaki Disease. target gene hsa-mir-124 "Carcinoma, Lung, Non-Small-Cell" 27924500 miR-124 modulates gefitinib resistance through SNAI2 and STAT3 in non-small cell lung cancer. target gene hsa-mir-206 "Carcinoma, Renal Cell" 27924503 miR-206 inhibits renal cell cancer growth by targeting GAK. target gene hsa-mir-205 Cervical Neoplasms 27929537 Upregulation of MiR-205 under hypoxia promotes epithelial-mesenchymal transition by targeting ASPP2. target gene hsa-mir-205 Lung Neoplasms 27929537 Upregulation of MiR-205 under hypoxia promotes epithelial-mesenchymal transition by targeting ASPP2. target gene hsa-mir-151 "Carcinoma, Breast" 27930738 miR-151-3p Targets TWIST1 to Repress Migration of Human Breast Cancer Cells. target gene hsa-mir-200c "Carcinoma, Lung, Non-Small-Cell" 27930974 miR-200c enhances sensitivity of drug-resistant non-small cell lung cancer to gefitinib by suppression of PI3K/Akt signaling pathway and inhibites cell migration via targeting ZEB1. target gene hsa-let-7a "Carcinoma, Hepatocellular" 27932893 Let-7a enhances the sensitivity of hepatocellular carcinoma cells to cetuximab by regulating STAT3 expression. target gene hsa-mir-145 "Carcinoma, Cervical" 27933466 "microRNA-145 modulates epithelial-mesenchymal transition and suppresses proliferation, migration and invasion by targeting SIP1 in human cervical cancer cells." target gene hsa-mir-125b Preeclampsia 27935985 miR-125b Enhances IL-8 Production in Early-Onset Severe Preeclampsia by Targeting Sphingosine-1-Phosphate Lyase 1. target gene hsa-mir-138 Psoriasis 27936398 MicroRNA138 regulates keratin 17 protein expression to affect HaCaT cell proliferation and apoptosis by targeting hTERT in psoriasis vulgaris. target gene hsa-mir-23a Rheumatoid Arthritis 27936459 MiR-23a inhibited IL-17-mediated proinflammatory mediators expression via targeting IKK¦Á in articular chondrocytes. target gene hsa-mir-181b Glioma 27938503 MicroRNA-181b Inhibits Cellular Proliferation and Invasion of Glioma Cells via Targeting Sal-Like Protein 4. target gene hsa-mir-98 "Carcinoma, Lung, Non-Small-Cell" 27938506 MicroRNA-98 Plays a Suppressive Role in Non-Small Cell Lung Cancer Through Inhibition of SALL4 Protein Expression. target gene hsa-mir-150 Systemic Lupus Erythematosus 27940256 Enhanced expression of TREM-1 in splenic cDCs in lupus prone mice and it was modulated by miRNA-150. target gene hsa-mir-141 "Carcinoma, Prostate" 27956179 MiR-141-3p promotes prostate cancer cell proliferation through inhibiting kruppel-like factor-9 expression. target gene hsa-mir-7 "Squamous Cell Carcinoma, Esophageal" 27956498 "In cytoplasm, CCAT1 regulates HOXB13 as a molecular decoy for miR-7, a microRNA that targets both CCAT1 and HOXB13, thus facilitating cell growth and migration" target gene hsa-mir-194 "Carcinoma, Prostate" 27959429 MicroRNA-194 suppresses prostate cancer migration and invasion by downregulating human nuclear distribution protein. target gene hsa-mir-326 Neoplasms [unspecific] 27960279 Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission. target gene hsa-mir-320a Polycystic Ovarian Syndrome 27965096 Deregulation of RUNX2 by miR-320a deficiency impairs steroidogenesis in cumulus granulosa cells from polycystic ovary syndrome (PCOS) patients. target gene hsa-mir-451a Cardiomyopathy 27974462 Down-regulation of microRNA-451a facilitates the activation and proliferation of CD4+ T cells by targeting Myc in patients with dilated cardiomyopathy. target gene hsa-mir-124 Inflammatory Bowel Diseases 27977009 Downregulated expression of microRNA-124 in pediatric intestinal failure patients modulates macrophages activation by inhibiting STAT3 and AChE. target gene hsa-mir-138 "Carcinoma, Bladder" 27978829 miR-138-5p contributes to cell proliferation and invasion by targeting Survivin in bladder cancer cells. target gene hsa-mir-200b Inflammatory Bowel Diseases 27979826 miR-200b inhibits TNF-¦Á-induced IL-8 secretion and tight junction disruption of intestinal epithelial cells in vitro. target gene hsa-mir-200a "Carcinoma, Colon" 27983967 MiR-200a acts as an oncogene in colorectal carcinoma by targeting PTEN. target gene hsa-mir-494 "Carcinoma, Ovarian" 27983981 CUL4A functions as an oncogene in ovarian cancer and is directly regulated by miR-494. target gene hsa-mir-130a "Carcinoma, Prostate" 27984115 Epigenetic disruption of miR-130a promotes prostate cancer by targeting SEC23B and DEPDC1. target gene hsa-mir-497 Heart Failure 27992564 MicroRNA-497 Inhibits Cardiac Hypertrophy by Targeting Sirt4. target gene hsa-mir-126 Atherosclerosis 27993686 MicroRNA-126 suppresses inflammation in endothelial cells under hyperglycemic condition by targeting HMGB1. target gene hsa-mir-506 "Carcinoma, Colon" 27993882 MicroRNA-506 Inhibits Malignancy of Colorectal Carcinoma Cells by Targeting LAMC1. target gene hsa-mir-29c Breast Neoplasms 27994679 Brown Seaweed Fucoidan Inhibits Cancer Progression by Dual Regulation of mir-29c/ADAM12 and miR-17-5p/PTEN Axes in Human Breast Cancer Cells. target gene hsa-mir-22 Heart Failure 27997889 MiR-22 may Suppress Fibrogenesis by Targeting TGF¦ÂR I in Cardiac Fibroblasts. target gene hsa-mir-520b "Carcinoma, Gastric" 27997901 MiR-520b/e Regulates Proliferation and Migration by Simultaneously Targeting EGFR in Gastric Cancer. target gene hsa-mir-520e "Carcinoma, Gastric" 27997901 MiR-520b/e Regulates Proliferation and Migration by Simultaneously Targeting EGFR in Gastric Cancer. target gene hsa-mir-143 "Carcinoma, Cervical" 27998464 miR-143 inhibits cell proliferation through targeted regulating the expression of K-ras gene in HeLa cells. target gene hsa-mir-340 "Carcinoma, Hepatocellular" 27998770 MicroRNA-340 inhibits the proliferation and invasion of hepatocellular carcinoma cells by targeting JAK1. target gene hsa-mir-130a Osteoarthritis 27999816 "miR-204, which targets RUNX2, and miR-130a, which inhibits PPAR¦Ã, were lower and higher, respectively, in F versus OA serum samples" target gene hsa-mir-204 Osteoarthritis 27999816 "miR-204, which targets RUNX2, and miR-130a, which inhibits PPAR¦Ã, were lower and higher, respectively, in F versus OA serum samples" target gene hsa-mir-487b Colorectal Carcinoma 28000854 Identification of microRNA-487b as a negative regulator of liver metastasis by regulation of KRAS in colorectal cancer. target gene hsa-mir-101 Colorectal Carcinoma 28000868 Methyl jasmonate induces the apoptosis of human colorectal cancer cells via downregulation of EZH2 expression by microRNA?101. target gene hsa-mir-1290 "Leukemia, Lymphoblastic, Acute" 28000876 miR-196b/miR-1290 participate in the antitumor effect of resveratrol via regulation of IGFBP3 expression in acute lymphoblastic leukemia. target gene hsa-mir-196b Leukemia 28000876 miR-196b/miR-1290 participate in the antitumor effect of resveratrol via regulation of IGFBP3 expression in acute lymphoblastic leukemia. target gene hsa-mir-302a Glioma 28000880 "MicroRNA-302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma." target gene hsa-mir-152 "Carcinoma, Nasopharyngeal" 28000885 "MicroRNA?152 inhibits cell proliferation, migration and invasion by directly targeting MAFB in nasopharyngeal carcinoma." target gene hsa-mir-631 Multiple Myeloma 28000886 hsa-miR-631 resensitizes bortezomib-resistant multiple myeloma cell lines by inhibiting UbcH10. target gene hsa-mir-26a "Adenocarcinoma, Lung" 28000891 Expression of miR?26a exhibits a negative correlation with HMGA1 and regulates cancer progression by targeting HMGA1 in lung adenocarcinoma cells. target gene hsa-mir-223 Testicular Germ Cell Tumor 28000896 miR?223?3p regulates cell growth and apoptosis via FBXW7 suggesting an oncogenic role in human testicular germ cell tumors. target gene hsa-mir-367 "Carcinoma, Lung, Non-Small-Cell" 28000899 miR-367 promotes the proliferation and invasion of non-small cell lung cancer via targeting FBXW7. target gene hsa-mir-24 "Carcinoma, Bladder" 28000900 "miR-24-3p regulates bladder cancer cell proliferation, migration, invasion and autophagy by targeting DEDD." target gene hsa-mir-375 "Squamous Cell Carcinoma, Oral" 28000902 MicroRNA?375 inhibits oral squamous cell carcinoma cell migration and invasion by targeting platelet?derived growth factor?A. target gene hsa-mir-221 Neuroblastoma 28003306 microRNA-221 Enhances MYCN via Targeting Nemo-like Kinase and Functions as an Oncogene Related to Poor Prognosis in Neuroblastoma. target gene hsa-mir-20a Colorectal Carcinoma 28004114 miR-20a-directed regulation of BID is associated with the TRAIL sensitivity in colorectal cancer. target gene hsa-mir-592 "Carcinoma, Lung, Non-Small-Cell" 28004116 miR-592 functions as a tumor suppressor in human non-small cell lung cancer by targeting SOX9. target gene hsa-mir-382 "Carcinoma, Lung, Non-Small-Cell" 28006750 miR-382 inhibits tumor progression by targeting SETD8 in non-small cell lung cancer. target gene hsa-mir-155 Ischemia-Reperfusion Injury 28006785 MiR-155 is Involved in Renal Ischemia-Reperfusion Injury via Direct Targeting of FoxO3a and Regulating Renal Tubular Cell Pyroptosis. target gene hsa-mir-215 Hirschsprung Disease 28006787 Role of MiR-215 in Hirschsprung's Disease Pathogenesis by Targeting SIGLEC-8. target gene hsa-mir-320a "Carcinoma, Gastric" 28008607 "MicroRNA-320a and microRNA-4496 attenuate Helicobacter pylori cytotoxin-associated gene A (CagA)-induced cancer-initiating potential and chemoresistance by targeting ¦Â-catenin and ATP-binding cassette, subfamily G, member 2." target gene hsa-mir-4496 "Carcinoma, Gastric" 28008607 "MicroRNA-320a and microRNA-4496 attenuate Helicobacter pylori cytotoxin-associated gene A (CagA)-induced cancer-initiating potential and chemoresistance by targeting ¦Â-catenin and ATP-binding cassette, subfamily G, member 2." target gene hsa-mir-194 "Carcinoma, Prostate" 28011622 MicroRNA-194 Promotes Prostate Cancer Metastasis by Inhibiting SOCS2. target gene hsa-mir-3941 "Adenocarcinoma, Lung" 28012229 miR-3941: A novel microRNA that controls IGBP1 expression and is associated with malignant progression of lung adenocarcinoma. target gene hsa-mir-381 "Carcinoma, Breast" 28012397 "miR-381 inhibited breast cancer cells proliferation, epithelial-to-mesenchymal transition and metastasis by targeting CXCR4." target gene hsa-mir-129 "Carcinoma, Gastric" 28012924 MiR-129 regulates cisplatin-resistance in human gastric cancer cells by targeting P-gp. target gene hsa-mir-590 "Adenocarcinoma, Lung" 28012926 miR-590 accelerates lung adenocarcinoma migration and invasion through directly suppressing functional target OLFM4. target gene hsa-mir-149 "Leukemia, Myeloid, Acute" 28013316 Inhibition of MicroRNA-149-5p Induces Apoptosis of Acute Myeloid Leukemia Cell Line THP-1 by Targeting Fas Ligand (FASLG). target gene hsa-mir-98 "Carcinoma, Colon" 28025745 MicroRNA-98 Suppress Warburg Effect by Targeting HK2 in Colon Cancer Cells. target gene hsa-mir-33b "Carcinoma, Hepatocellular" 28026002 MicroRNA-33b suppresses the proliferation and metastasis of hepatocellular carcinoma cells through the inhibition of Sal-like protein 4 expression. target gene hsa-mir-19b Antiphospholipid Syndrome 28028298 MicroRNA expression in antiphospholipid syndrome: a systematic review and microRNA target genes analysis. target gene hsa-mir-20a Antiphospholipid Syndrome 28028298 MicroRNA expression in antiphospholipid syndrome: a systematic review and microRNA target genes analysis. target gene hsa-mir-200b "Carcinoma, Prostate" 28028835 TIMP4 expression is regulated by miR-200b-3p in prostate cancer cells. target gene hsa-mir-200c Neoplasms [unspecific] 28029649 MiR-200c is a cMyc-activated miRNA that promotes nasopharyngeal carcinoma by downregulating PTEN. target gene hsa-mir-195 Osteosarcoma 28032380 MicroRNA-195-5p suppresses osteosarcoma cell proliferation and invasion by suppressing naked cuticle homolog 1. target gene hsa-mir-216a "Carcinoma, Pancreatic" 28034748 "MiR-216a decreases MALAT1 expression, induces G2/M arrest and apoptosis in pancreatic cancer cells." target gene hsa-mir-137 "Carcinoma, Colon" 28035913 MicroRNA-137 chemosensitizes colon cancer cells to the chemotherapeutic drug oxaliplatin (OXA) by targeting YBX1. target gene hsa-mir-603 "Carcinoma, Breast, Triple Negative" 28036267 MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase. target gene hsa-mir-224 Pancreatic Neoplasms 28036293 A retrospective study of NENs and miR-224 promotes apoptosis of BON-1 cells by targeting PCSK9 inhibition. target gene hsa-mir-96 "Diabetes Mellitus, Type 2" 28036389 Induction of miR-96 by Dietary Saturated Fatty Acids Exacerbates Hepatic Insulin Resistance through the Suppression of INSR and IRS-1. target gene hsa-mir-10b Ankylosing Spondylitis 28039186 miR-10b-5p is a novel Th17 regulator present in Th17 cells from ankylosing spondylitis. target gene hsa-mir-194 Psoriasis 28040329 MicroRNA-194 regulates keratinocyte proliferation and differentiation by targeting Grainyhead-like 2 in psoriasis. target gene hsa-mir-124 Glioblastoma 28040710 REST represses miR-124 and miR-203 to regulate distinct oncogenic properties of glioblastoma stem cells. target gene hsa-mir-203 Glioblastoma 28040710 REST represses miR-124 and miR-203 to regulate distinct oncogenic properties of glioblastoma stem cells. target gene hsa-mir-130b "Carcinoma, Bladder" 28042869 Genome-Wide Screen of miRNAs and Targeting mRNAs Reveals the Negatively Regulatory Effect of miR-130b-3p on PTEN by PI3K and Integrin ¦Â1 Signaling Pathways in Bladder Carcinoma. target gene hsa-mir-486 Leukemia 28043832 Exosomal miR-486 regulates hypoxia-induced erythroid differentiation of erythroleukemia cells through targeting Sirt1. target gene hsa-mir-181a "Carcinoma, Gastric" 28043911 miR-181a-5p promotes the progression of gastric cancer via RASSF6-mediated MAPK signalling activation. target gene hsa-mir-134 "Carcinoma, Ovarian" 28043921 MicroRNA-134-3p is a novel potential inhibitor of human ovarian cancer stem cells by targeting RAB27A. target gene hsa-mir-330 "Carcinoma, Hepatocellular" 28050784 Roles of microRNA-330 and Its Target Gene ING4 in the Development of Aggressive Phenotype in Hepatocellular Carcinoma Cells. target gene hsa-mir-204 "Carcinoma, Prostate" 28050800 Micro-RNA-204 Participates in TMPRSS2/ERG Regulation and Androgen Receptor Reprogramming in Prostate Cancer. target gene hsa-mir-365 Atherosclerosis 28051250 MiR-365 participates in coronary atherosclerosis through regulating IL-6. target gene hsa-mir-145 Osteosarcoma 28051259 "MicroRNA-145 inhibits tumour growth and metastasis in osteosarcoma by targeting cyclin-dependent kinase, CDK6." target gene hsa-mir-138 "Carcinoma, Pancreatic" 28052003 miR-138-5p suppresses autophagy in pancreatic cancer by targeting SIRT1. target gene hsa-mir-761 "Carcinoma, Breast, Triple Negative" 28054302 microRNA-761 induces aggressive phenotypes in triple-negative breast cancer cells by repressing TRIM29 expression. target gene hsa-mir-223 Rheumatoid Arthritis 28056105 miR-223-3p may contribute to the pathogenesis of RA by downregulating the expression of IL-17RD and upregulating that of IL-6 in synovial cells target gene hsa-mir-93 Osteosarcoma 28056303 MiR-93 targets NKD2 to promote proliferation and inhibit apoptosis of osteosarcoma cells target gene hsa-let-7a Neoplasms [unspecific] 28057739 the let-7-HMGA2 axis plays a prominent role in the pathogenesis of the disease that leads to unique clinical phenotypes target gene hsa-mir-92a "Leukemia, Myeloid, Acute" 28059050 miR-92a Inhibits Proliferation and Induces Apoptosis by Regulating Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2) Expression in Acute Myeloid Leukemia. target gene hsa-let-7a Heart Failure 28060734 Let-7a regulates expression of ¦Â1-adrenoceptors and forms a negative feedback circuit with the ¦Â1-adrenoceptor signaling pathway in chronic ischemic heart failure. target gene hsa-mir-107 Acute Kidney Failure 28063928 MiR-107 induces TNF-¦Á secretion in endothelial cells causing tubular cell injury in patients with septic acute kidney injury. target gene hsa-mir-148a "Carcinoma, Breast" 28063929 MiR-148a and miR-152 reduce tamoxifen resistance in ER+ breast cancer via downregulating ALCAM. target gene hsa-mir-152 "Carcinoma, Breast" 28063929 MiR-148a and miR-152 reduce tamoxifen resistance in ER+ breast cancer via downregulating ALCAM. target gene hsa-mir-129 Glioblastoma 28068630 "Potential mechanisms of microRNA-129-5p in inhibiting cell processes including viability, proliferation, migration and invasiveness of glioblastoma cells U87 through targeting FNDC3B." target gene hsa-mir-202 "Scleroderma, Systemic" 28068631 MicroRNA-202-3p regulates scleroderma fibrosis by targeting matrix metalloproteinase 1. target gene hsa-mir-495 "Carcinoma, Bladder" 28069380 microRNA-495 promotes bladder cancer cell growth and invasion by targeting phosphatase and tensin homolog. target gene hsa-mir-375 "Squamous Cell Carcinoma, Esophageal" 28069583 MiR-375 suppresses invasion and metastasis by direct targeting of SHOX2 in esophageal squamous cell carcinoma. target gene hsa-mir-150 Osteosarcoma 28070040 MicroRNA-150 inhibits osteosarcoma cell proliferation by targeting RUNX2 gene. target gene hsa-mir-718 "Carcinoma, Hepatocellular" 28070994 "Involvement of microRNA-718, a new regulator of EGR3, in regulation of malignant phenotype of HCC cells." target gene hsa-mir-34c Osteosarcoma 28075441 miR?34c?3p acts as a tumor suppressor gene in osteosarcoma by targeting MARCKS. target gene hsa-mir-191 "Carcinoma, Lung, Non-Small-Cell" 28075452 "A novel pathway in NSCLC cells: miR?191, targeting NFIA, is induced by chronic hypoxia, and promotes cell proliferation and migration." target gene hsa-mir-375 "Carcinoma, Breast" 28075453 miR-375 inhibits cancer stem cell phenotype and tamoxifen resistance by degrading HOXB3 in human ER-positive breast cancer. target gene hsa-mir-138 "Carcinoma, Nasopharyngeal" 28075468 MicroRNA-138-5p controls sensitivity of nasopharyngeal carcinoma to radiation by targeting EIF4EBP1. target gene hsa-mir-134 "Carcinoma, Lung, Non-Small-Cell" 28075475 miR-134 suppresses the migration and invasion of non?small cell lung cancer by targeting ITGB1. target gene hsa-mir-214 "Carcinoma, Lung, Non-Small-Cell" 28076844 Sulforaphane inhibits cancer stem-like cell properties and cisplatin resistance through miR-214-mediated downregulation of c-MYC in non-small cell lung cancer. target gene hsa-mir-15a Intervertebral Disc Degeneration 28081468 Role of miR-15a in intervertebral disc degeneration through targeting MAP3K9. target gene hsa-mir-200a "Carcinoma, Hepatocellular" 28081727 MicroRNA-200a Suppresses Cell Invasion and Migration by Directly Targeting GAB1 in Hepatocellular Carcinoma. target gene hsa-mir-377 "Carcinoma, Hepatocellular" 28081730 MicroRNA-377 Downregulates Bcl-xL and Increases Apoptosis in Hepatocellular Carcinoma Cells. target gene hsa-mir-17 Glioma 28081732 Inhibition of Beclin-1-Mediated Autophagy by MicroRNA-17-5p Enhanced the Radiosensitivity of Glioma Cells. target gene hsa-mir-214 Osteosarcoma 28081735 miR-214-5p Targets ROCK1 and Suppresses Proliferation and Invasion of Human Osteosarcoma Cells. target gene hsa-mir-940 "Carcinoma, Ovarian" 28081739 miR-940 Upregulation Suppresses Cell Proliferation and Induces Apoptosis by Targeting PKC-¦Ä in Ovarian Cancer OVCAR3 Cells. target gene hsa-mir-424 "Carcinoma, Cervical" 28082020 miR424-5p functions as an anti-oncogene in cervical cancer cell growth by targeting KDM5B via the Notch signaling pathway. target gene hsa-mir-125b Inflammatory Bowel Diseases 28082316 miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoea. target gene hsa-mir-16 Inflammatory Bowel Diseases 28082316 miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoea. target gene hsa-mir-23b Chondrosarcoma 28085008 Inhibition of Src by microRNA-23b increases the cisplatin sensitivity of chondrosarcoma cells. target gene hsa-mir-130a Psoriasis 28085489 microRNA-130a Promotes Human Keratinocyte Viability and Migration and Inhibits Apoptosis Through Direct Regulation of STK40-Mediated NF-¦ÊB Pathway and Indirect Regulation of SOX9-Meditated JNK/MAPK Pathway: A Potential Role in Psoriasis. target gene hsa-mir-451 Osteosarcoma 28086136 "MiR-451 suppresses proliferation, migration and promotes apoptosis of the human osteosarcoma by targeting macrophage migration inhibitory factor." target gene hsa-mir-1307 "Carcinoma, Ovarian" 28086946 MiR-1307 promotes ovarian cancer cell chemoresistance by targeting the ING5 expression. target gene hsa-mir-449a Liver Neoplasms 28088579 The microRNA-449 family inhibits TGF-¦Â-mediated liver cancer cell migration by targeting SOX4. target gene hsa-mir-449b Liver Neoplasms 28088579 The microRNA-449 family inhibits TGF-¦Â-mediated liver cancer cell migration by targeting SOX4. target gene hsa-mir-30c "Fatty Liver, Non-Alcoholic" 28088781 MiR-30c-5p ameliorates hepatic steatosis in leptin receptor-deficient (db/db) mice via down-regulating FASN. target gene hsa-mir-195 "Carcinoma, Renal Cell, Clear-Cell" 28089832 Androgen receptor (AR) promotes clear cell renal cell carcinoma (ccRCC) migration and invasion via altering the circHIAT1/miR-195-5p/29a-3p/29c-3p/CDC42 signals. target gene hsa-mir-29a "Carcinoma, Renal Cell, Clear-Cell" 28089832 Androgen receptor (AR) promotes clear cell renal cell carcinoma (ccRCC) migration and invasion via altering the circHIAT1/miR-195-5p/29a-3p/29c-3p/CDC42 signals. target gene hsa-mir-29c "Carcinoma, Renal Cell, Clear-Cell" 28089832 Androgen receptor (AR) promotes clear cell renal cell carcinoma (ccRCC) migration and invasion via altering the circHIAT1/miR-195-5p/29a-3p/29c-3p/CDC42 signals. target gene hsa-mir-141 "Carcinoma, Ovarian" 28095864 MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis. target gene hsa-mir-155 Human Immunodeficiency Virus Infection 28096489 "miR-155 and miR-92a, were reported previously to at least weakly bind HIV-1 transcripts" target gene hsa-mir-92a Human Immunodeficiency Virus Infection 28096489 "miR-155 and miR-92a, were reported previously to at least weakly bind HIV-1 transcripts" target gene hsa-mir-345 "Carcinoma, Hepatocellular" 28098858 miR-345 inhibits tumor metastasis and EMT by targeting IRF1-mediated mTOR/STAT3/AKT pathway in hepatocellular carcinoma. target gene hsa-mir-34b "Carcinoma, Hepatocellular" 28098861 Triptolide inhibits viability and induces apoptosis in liver cancer cells through activation of the tumor suppressor gene p53. target gene hsa-mir-34c "Carcinoma, Hepatocellular" 28098861 Triptolide inhibits viability and induces apoptosis in liver cancer cells through activation of the tumor suppressor gene p53. target gene hsa-mir-187 "Carcinoma, Gastric" 28098868 MicroRNA-187 promotes growth and metastasis of gastric cancer by inhibiting FOXA2. target gene hsa-mir-148a "Carcinoma, Renal Cell" 28098870 miR-148a increases the sensitivity to cisplatin by targeting Rab14 in renal cancer cells. target gene hsa-mir-375 "Carcinoma, Lung, Non-Small-Cell" 28098887 miRNA?375 regulates the cell survival and apoptosis of human non?small cell carcinoma by targeting HER2. target gene hsa-mir-194 Glioma 28098896 MicroRNA-194 represses glioma cell epithelial?to?mesenchymal transition by targeting Bmi1. target gene hsa-mir-9 Liver Cirrhosis 28098912 MicroRNA-9 limits hepatic fibrosis by suppressing the activation and proliferation of hepatic stellate cells by directly targeting MRP1/ABCC1. target gene hsa-mir-1296 "Carcinoma, Gastric" 28099468 miR 1296-5p Inhibits the Migration and Invasion of Gastric Cancer Cells by Repressing ERBB2 Expression. target gene hsa-mir-27a "Carcinoma, Breast" 28099945 "In vivo and in vitro effects of microRNA-27a on proliferation, migration and invasion of breast cancer cells through targeting of SFRP1 gene via Wnt/¦Â-catenin signaling pathway." target gene hsa-mir-221 "Squamous Cell Carcinoma, Oral" 28101204 Downregulation of miR-221/222 by a microRNA sponge promotes apoptosis in oral squamous cell carcinoma cells through upregulation of PTEN. target gene hsa-mir-222 "Squamous Cell Carcinoma, Oral" 28101204 Downregulation of miR-221/222 by a microRNA sponge promotes apoptosis in oral squamous cell carcinoma cells through upregulation of PTEN. target gene hsa-mir-15a "Leukemia, Lymphoblastic, Acute, B-Cell" 28101583 we proposed a cellular model to discuss MYC/miR-15a-5p/FLT3 feed-forward loop?(FFL) with Jak-STAT signaling pathway in B-ALL target gene hsa-mir-181a "Leukemia, Myelogenous, Chronic, BCR-ABL Positive" 28103766 inhibition of miR-181a using a microRNA sponge inhibitor resulted in decreased transcription of SOX2 and SALL4 target gene hsa-mir-145 "Carcinoma, Hepatocellular" 28104805 MicroRNA-145 Modulates N6-Methyladenosine Levels by Targeting the 3'-Untranslated mRNA Region of the N6-Methyladenosine Binding YTH Domain Family 2 Protein. target gene hsa-mir-150 Lung Neoplasms 28108217 CDK3 is a major target of miR-150 in cell proliferation and anti-cancer effect. target gene hsa-mir-543 Osteosarcoma 28108312 CTGF promotes osteosarcoma angiogenesis by regulating miR-543/angiopoietin 2 signaling. target gene hsa-mir-125b Melanoma 28108732 FAK regulates E-cadherin expression via p-SrcY416/p-ERK1/2/p-Stat3Y705 and PPAR¦Ã/miR-125b/Stat3 signaling pathway in B16F10 melanoma cells. target gene hsa-mir-143 "Carcinoma, Prostate" 28109198 miR-143 Induces the Apoptosis of Prostate Cancer LNCap Cells by Suppressing Bcl-2 Expression. target gene hsa-mir-214 Bone Disease [unspecific] 28109866 "miR-214 suppresses osteogenesis by targeting BIRC7, providing a possible therapeutic target for bone degenerative diseases" target gene hsa-mir-150 Atherosclerosis 28110404 MicroRNA-150 targets ELK1 and modulates the apoptosis induced by ox-LDL in endothelial cells. target gene hsa-mir-144 "Carcinoma, Gastric" 28111340 MicroRNA-144-3p suppresses gastric cancer progression by inhibiting epithelial-to-mesenchymal transition through targeting PBX3. target gene hsa-mir-191a Inflammatory Bowel Diseases 28111380 Baicalin Protects against TNF-¦Á-Induced Injury by Down-Regulating miR-191a That Targets the Tight Junction Protein ZO-1 in IEC-6 Cells. target gene hsa-mir-520c "Carcinoma, Breast" 28112380 miR520c blocks EMT progression of human breast cancer cells by repressing STAT3. target gene hsa-mir-22 Heart Failure 28112401 MicroRNA-22 regulates inflammation and angiogenesis via targeting VE-cadherin. target gene hsa-mir-206 Vascular Hypertrophy 28114137 MiR-206 affected the process of cardiomyocytes hypertrophy by regulating histone deacetylase 4 (HDAC4) target gene hsa-mir-939 Coronary Artery Disease 28115160 MicroRNA-939 governs vascular integrity and angiogenesis through targeting ¦Ã-catenin in endothelial cells. target gene hsa-mir-141 "Carcinoma, Gastric" 28115163 Lnc-ATB contributes to gastric cancer growth through a MiR-141-3p/TGF¦Â2 feedback loop. target gene hsa-mir-379 "Carcinoma, Lung, Non-Small-Cell" 28117895 Suppression of EIF4G2 by miR-379 potentiates the cisplatin chemosensitivity in nonsmall cell lung cancer cells. target gene hsa-mir-518 "Squamous Cell Carcinoma, Esophageal" 28119087 miR-518 inhibited the proliferation and invasion of esophageal squamous cell carcinoma (ESCC) cells possibly by targeting RAP1B target gene hsa-mir-145 "Adenocarcinoma, Lung" 28120164 MiRNA-145 suppresses lung adenocarcinoma cell invasion and migration by targeting N-cadherin. target gene hsa-mir-542 "Carcinoma, Breast" 28121348 miR-542-3p targets sphingosine-1-phosphate receptor 1 and regulates cell proliferation and invasion of breast cancer cells. target gene hsa-mir-590 "Carcinoma, Breast" 28121351 MicroRNA miR-590-5p inhibits breast cancer cell stemness and metastasis by targeting SOX2. target gene hsa-mir-1307 "Carcinoma, Prostate" 28122308 miR-1307 promotes the proliferation of prostate cancer by targeting FOXO3A. target gene hsa-mir-125b "Carcinoma, Thyroid, Anaplastic" 28122310 MiR-125b inhibits anaplastic thyroid cancer cell migration and invasion by targeting PIK3CD. target gene hsa-mir-182 "Carcinoma, Thyroid, Medullary" 28122586 MiR-182 promotes cancer invasion by linking RET oncogene activated NF-¦ÊB to loss of the HES1/Notch1 regulatory circuit. target gene hsa-let-7a Vascular Hypertrophy 28123343 Let-7a Is an Antihypertrophic Regulator in the Heart via Targeting Calmodulin. target gene hsa-mir-18a Glioblastoma 28123848 The malignancy of miR-18a in human glioblastoma via directly targeting CBX7. target gene hsa-mir-34c Neoplasms [unspecific] 28125315 miRNA-34c inhibits myoblasts proliferation by targeting YY1. target gene hsa-mir-199a "Carcinoma, Breast" 28126676 MiR-199a-3p enhances breast cancer cell sensitivity to cisplatin by downregulating TFAM (TFAM). target gene hsa-mir-26a Neoplasms [unspecific] 28126920 Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR. target gene hsa-mir-9 "Carcinoma, Gastric" 28127811 MicroRNA-9 inhibits the gastric cancer cell proliferation by targeting TNFAIP8. target gene hsa-mir-187 "Carcinoma, Cervical" 28128400 miR-187 induces apoptosis of SiHa cervical carcinoma cells by downregulating Bcl-2. target gene hsa-mir-146 Breast Neoplasms 28128741 miR-146a and miR-146-5p silencing BRCA1 may trigger formation of triple-negative and basal-like sporadic BC cases target gene hsa-mir-92a Alzheimer Disease 28129110 "the AD-like tau accumulation induces anxiety through disrupting miR92a-vGAT-GABA signaling, which reveals molecular mechanisms underlying the anxiety behavior in AD patients and potentially leads to the development of new therapeutics for tauopathies" target gene hsa-mir-21 Immune System Disease [unspecific] 28129531 MicroRNA-21 contributes to suppress cytokines production by targeting TLR28 in teleost fish. target gene hsa-mir-650 Rheumatoid Arthritis 28129626 "MiR-650 inhibits proliferation, migration and invasion of rheumatoid arthritis synovial fibroblasts by targeting AKT2." target gene hsa-mir-34a "Carcinoma, Hepatocellular" 28129650 MicroRNA-34a regulates liver regeneration and the development of liver cancer in rats by targeting Notch signaling pathway. target gene hsa-mir-365 Heart Failure 28130111 MicroRNA-365 accelerates cardiac hypertrophy by inhibiting autophagy via the modulation of Skp2 expression. target gene hsa-mir-18a Lung Fibrosis 28131417 miR-18a-5p Inhibits Sub-pleural Pulmonary Fibrosis by Targeting TGF-¦Â Receptor II. target gene hsa-mir-146a Influenza 28131813 MicroRNA-146a induction during influenza H3N2 virus infection targets and regulates TRAF6 levels in human nasal epithelial cells (hNECs). target gene hsa-mir-141 Hepatitis B Virus Infection 28135713 MicroRNA-141 Targets Sirt1 and Inhibits Autophagy to Reduce HBV Replication. target gene hsa-mir-214 "Carcinoma, Cervical" 28137590 miR-214 down-regulates ARL2 and suppresses growth and invasion of cervical cancer cells. target gene hsa-mir-21 "Squamous Cell Carcinoma, Head and Neck" 28138036 Suppression of the Growth and Invasion of Human Head and Neck Squamous Cell Carcinomas via Regulating STAT3 Signaling and the miR-21/¦Â-catenin Axis with HJC0152. target gene hsa-mir-410 Osteosarcoma 28138700 MicroRNA-410 regulates autophagy-related gene ATG16L1 expression and enhances chemosensitivity via autophagy inhibition in osteosarcoma. target gene hsa-mir-101 "Carcinoma, Renal Cell, Clear-Cell" 28138701 Hypoxia-induced hsa-miR-101 promotes glycolysis by targeting TIGAR mRNA in clear cell renal cell carcinoma. target gene hsa-mir-155 "Carcinoma, Pancreatic" 28152544 "Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK." target gene hsa-mir-138 Leukemia 28153721 MiR-138 indirectly regulates the MDR1 promoter by NF-¦ÊB/p65 silencing. target gene hsa-mir-1271 "Carcinoma, Prostate" 28153722 Inhibition of DIXDC1 by microRNA-1271 suppresses the proliferation and invasion of prostate cancer cells. target gene hsa-mir-34a "Leukemia, Myeloid, Chronic" 28157629 The epigenetically-regulated miR-34a targeting c-SRC suppresses RAF/MEK/ERK signaling pathway in K-562 cells. target gene hsa-mir-1 Breast Neoplasms 28159933 Tumor suppressor miR-1 inhibits tumor growth and metastasis by simultaneously targeting multiple genes. target gene hsa-mir-495 "Carcinoma, Gastric" 28159956 MicroRNA-495 Inhibits Gastric Cancer Cell Migration and Invasion Possibly via Targeting High Mobility Group AT-Hook 2 (HMGA2). target gene hsa-mir-320a Glioma 28160566 "miR-320a functions as a suppressor for gliomas by targeting SND1 and ¦Â-catenin, and predicts the prognosis of patients." target gene hsa-mir-130b "Carcinoma, Breast" 28163094 miR-130b-3p inhibits cell invasion and migration by targeting the Notch ligand Delta-like 1 in breast carcinoma. target gene hsa-mir-29b Cardiovascular Diseases [unspecific] 28164126 The Involvement of miR-29b-3p in Arterial Calcification by Targeting Matrix Metalloproteinase-2. target gene hsa-mir-15b "Squamous Cell Carcinoma, Skin or Unspecific" 28165568 MicroRNA15b regulates apoptosis of cutaneous squamous cell carcinoma SCL-1 cell line: a mechanism study. target gene hsa-mir-212 "Carcinoma, Cervical" 28165569 Effect of miR-212 targeting TCF7L2 on the proliferation and metastasis of cervical cancer. target gene hsa-mir-599 "Carcinoma, Lung, Non-Small-Cell" 28167280 The miR-599 promotes non-small cell lung cancer cell invasion via SATB2. target gene hsa-mir-29c Gastric Neoplasms 28173777 microRNA-29c inhibits cell proliferation by targeting NASP in human gastric cancer. target gene hsa-mir-224 "Carcinoma, Gastric" 28173803 "Hypoxia-inducible microRNA-224 promotes the cell growth, migration and invasion by directly targeting RASSF8 in gastric cancer." target gene hsa-mir-143 "Squamous Cell Carcinoma, Oral" 28174335 "MicroRNA-143 suppresses oral squamous cell carcinoma cell growth, invasion and glucose metabolism through targeting hexokinase 2." target gene hsa-mir-181 Osteoarthritis 28177757 MicroRNA-181 inhibits proliferation and promotes apoptosis of chondrocytes in osteoarthritis by targeting PTEN. target gene hsa-mir-361 Glioma 28184914 MicroRNA-361-5p inhibits epithelial-to-mesenchymal transition of glioma cells through targeting Twist1. target gene hsa-mir-30d "Squamous Cell Carcinoma, Esophageal" 28184915 MicroRNA-30d inhibits the migration and invasion of human esophageal squamous cell carcinoma cells via the post?transcriptional regulation of enhancer of zeste homolog?2. target gene hsa-mir-922 "Carcinoma, Hepatocellular" 28184924 miR-922 regulates CYLD expression and promotes the cell proliferation of human hepatocellular carcinoma. target gene hsa-mir-217 "Carcinoma, Hepatocellular" 28184926 "miR-217 suppresses proliferation, migration, and invasion promoting apoptosis via targeting MTDH in hepatocellular carcinoma." target gene hsa-mir-520c Glioma 28184932 MicroRNA-520c inhibits glioma cell migration and invasion by the suppression of transforming growth factor-¦Â receptor type?2. target gene hsa-mir-93 Bone Disease [unspecific] 28186136 FOXO1-suppressed miR-424 regulates the proliferation and osteogenic differentiation of MSCs by targeting FGF2 under oxidative stress. target gene hsa-mir-28 "Lymphoma, Hodgkin" 28188132 miR-28 regulates the germinal center reaction and blocks tumor growth in preclinical models of non-Hodgkin lymphoma. target gene hsa-mir-125a "Carcinoma, Breast" 28188287 A-to-I RNA Editing Up-regulates Human Dihydrofolate Reductase in Breast Cancer. target gene hsa-mir-25 "Carcinoma, Breast" 28188287 A-to-I RNA Editing Up-regulates Human Dihydrofolate Reductase in Breast Cancer. target gene hsa-mir-675 "Carcinoma, Colon" 28189050 "H19 Overexpression Induces Resistance to 1,25(OH)2D3 by Targeting VDR Through miR-675-5p in Colon Cancer Cells." target gene hsa-mir-29a Diabetic Retinopathy 28189547 Role of microRNA-29a in the development of diabetic retinopathy by targeting AGT gene in a rat model. target gene hsa-mir-24 Osteosarcoma 28189676 miR-24 represses metastasis of human osteosarcoma cells by targeting Ack1 via AKT/MMPs pathway. target gene hsa-mir-30b "Carcinoma, Esophageal" 28189678 "miR-30b inhibits cancer cell growth, migration, and invasion by targeting homeobox A1 in esophageal cancer." target gene hsa-mir-218 "Carcinoma, Lung" 28192397 Downregulation of miR-218 contributes to epithelial-mesenchymal transition and tumor metastasis in lung cancer by targeting Slug/ZEB2 signaling. target gene hsa-mir-143 "Adenocarcinoma, Pancreatic Ductal" 28194669 MiR-143 Targeting TAK1 Attenuates Pancreatic Ductal Adenocarcinoma Progression via MAPK and NF-¦ÊB Pathway In Vitro. target gene hsa-mir-451 "Carcinoma, Pancreatic" 28197410 MiR-451 Promotes Cell Proliferation and Metastasis in Pancreatic Cancer through Targeting CAB39. target gene hsa-mir-133a Ischemia-Reperfusion Injury 28198596 Propofol protects against hepatic ischemia/reperfusion injury via miR-133a-5p regulating the expression of MAPK6. target gene hsa-mir-205 Lung Neoplasms 28199217 MicroRNA-205 targets SMAD4 in non-small cell lung cancer and promotes lung cancer cell growth in vitro and in vivo. target gene hsa-mir-146a "Carcinoma, Lung, Non-Small-Cell" 28202053 Up-regulation of miR-146a increases the sensitivity of non-small cell lung cancer to DDP by downregulating cyclin J. target gene hsa-mir-146a Stroke 28202285 Decreased miR-146a expression in acute ischemic stroke directly targets the Fbxl10 mRNA and is involved in modulating apoptosis. target gene hsa-mir-101 Alzheimer Disease 28202389 Targeting the HDAC2/HNF-4A/miR-101b/AMPK Pathway Rescues Tauopathy and Dendritic Abnormalities in Alzheimer's Disease. target gene hsa-mir-520f Neoplasms [unspecific] 28209612 miRNA-520f Reverses Epithelial-to-Mesenchymal Transition by Targeting ADAM9 and TGFBR2. target gene hsa-mir-92a "Carcinoma, Ovarian" 28209618 The STAT3-miRNA-92-Wnt Signaling Pathway Regulates Spheroid Formation and Malignant Progression in Ovarian Cancer. target gene hsa-mir-718 Sepsis 28209713 miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN). target gene hsa-mir-124 "Squamous Cell Carcinoma, Head and Neck" 28212569 MiR-124 acts as a tumor suppressor by inhibiting the expression of sphingosine kinase 1 and its downstream signaling in head and neck squamous cell carcinoma. target gene hsa-mir-216a "Carcinoma, Colon" 28213952 Down-regulation of KIAA1199/CEMIP by miR-216a suppresses tumor invasion and metastasis in colorectal cancer. target gene hsa-mir-155 Osteosarcoma 28214207 MicroRNA-155 targets MAP3K10 and regulates osteosarcoma cell growth. target gene hsa-mir-15a "Aortic Aneurysm, Abdominal" 28214350 Upregulation of MicroRNA-15a Contributes to Pathogenesis of Abdominal Aortic Aneurysm (AAA) by Modulating the Expression of Cyclin-Dependent Kinase Inhibitor 2B (CDKN2B). target gene hsa-mir-183 Pain 28214854 MicroRNA-183 Suppresses Neuropathic Pain and Expression of AMPA Receptors by Targeting mTOR/VEGF Signaling Pathway. target gene hsa-mir-26a "Adenocarcinoma, Lung" 28214878 MiRNA-26a Contributes to the Acquisition of Malignant Behaviors of Doctaxel-Resistant Lung Adenocarcinoma Cells through Targeting EZH2. target gene hsa-mir-32 Mycobacterium tuberculosis Infection 28215633 TLR-4/miRNA-32-5p/FSTL1 signaling regulates mycobacterial survival and inflammatory responses in Mycobacterium tuberculosis-infected macrophages. target gene hsa-mir-153 Glioblastoma 28218035 MicroRNA-153 regulates glutamine metabolism in glioblastoma through targeting glutaminase. target gene hsa-mir-139 Alzheimer Disease 28218780 MicroRNA-139 modulates Alzheimer's-associated pathogenesis in SAMP8 mice by targeting cannabinoid receptor type 2. target gene hsa-mir-218 "Carcinoma, Bladder" 28222430 MicroRNA-218 Increases the Sensitivity of Bladder Cancer to Cisplatin by Targeting Glut1. target gene hsa-mir-29b "Carcinoma, Endometrial" 28222438 MicroRNA-29b Inhibits Angiogenesis by Targeting VEGFA through the MAPK/ERK and PI3K/Akt Signaling Pathways in Endometrial Carcinoma. target gene hsa-mir-29a Breast Neoplasms 28222663 miR-29a suppresses MCF-7 cell growth by downregulating tumor necrosis factor receptor 1. target gene hsa-mir-181 "Carcinoma, Breast" 28224609 miR-181 elevates Akt signaling by co-targeting PHLPP2 and INPP4B phosphatases in luminal breast cancer. target gene hsa-mir-216a Melanoma 28225180 microRNA-216b inhibits cell proliferation and migration in human melanoma by targeting FOXM1 in vitro and in vivo. target gene hsa-mir-15b Multiple Sclerosis 28228555 MicroRNA-15b Suppresses Th17 Differentiation and Is Associated with Pathogenesis of Multiple Sclerosis by Targeting O-GlcNAc Transferase. target gene hsa-mir-144 "Carcinoma, Hepatocellular" 28229969 "MicroRNA-144 inhibits hepatocellular carcinoma cell proliferation, invasion and migration by targeting ZFX." target gene hsa-mir-21 Diabetes Mellitus 28230206 MiRNA-21 mediates the antiangiogenic activity of metformin through targeting PTEN and SMAD7 expression and PI3K/AKT pathway. target gene hsa-mir-302b "Carcinoma, Lung" 28231299 miR-34a-5p/miR-34c-5p/miR-302b-3p-LEF1-CCND1/WNT2/MYC axis may be a crucial mechanism in inhibition of lung cancer metastasis by curcumin target gene hsa-mir-34a "Carcinoma, Lung" 28231299 miR-34a-5p/miR-34c-5p/miR-302b-3p-LEF1-CCND1/WNT5/MYC axis may be a crucial mechanism in inhibition of lung cancer metastasis by curcumin target gene hsa-mir-34c "Carcinoma, Lung" 28231299 miR-34a-5p/miR-34c-5p/miR-302b-3p-LEF1-CCND1/WNT6/MYC axis may be a crucial mechanism in inhibition of lung cancer metastasis by curcumin target gene hsa-mir-22 "Carcinoma, Prostate" 28231399 MTA1-activated Epi-microRNA-22 regulates E-cadherin and prostate cancer invasiveness. target gene hsa-mir-543 "Carcinoma, Cervical" 28231728 MicroRNA-543 acts as a prognostic marker and promotes the cell proliferation in cervical cancer by BRCA1-interacting protein 1. target gene hsa-mir-122 "Carcinoma, Renal Cell" 28231730 MiR-122 promotes renal cancer cell proliferation by targeting Sprouty2. target gene hsa-mir-221 Liver Injury 28232457 Dicer-dependent production of microRNA221 in hepatocytes inhibits p27 and is required for liver regeneration in mice. target gene hsa-let-7 "Carcinoma, Lung, Non-Small-Cell" 28235063 Disturbance of the let-7/LIN28 double-negative feedback loop is associated with radio- and chemo-resistance in non-small cell lung cancer. target gene hsa-mir-106b Acute Myocardial Infarction 28235791 High-throughput screening identifies microRNAs that target Nox2 and improve function after acute myocardial infarction. target gene hsa-mir-148b Acute Myocardial Infarction 28235791 High-throughput screening identifies microRNAs that target Nox2 and improve function after acute myocardial infarction. target gene hsa-mir-204 Acute Myocardial Infarction 28235791 High-throughput screening identifies microRNAs that target Nox2 and improve function after acute myocardial infarction. target gene hsa-mir-181b Aortic Valve Disease 28236165 Mechanosensitive microRNA-181b Regulates Aortic Valve Endothelial Matrix Degradation by Targeting TIMP3. target gene hsa-mir-26a "Carcinoma, Lung" 28237093 MiR-26a enhances invasive capacity by suppressing GSK3¦Â in human lung cancer cells. target gene hsa-mir-15b "Carcinoma, Hepatocellular" 28239814 microRNA15b induced SMCC7721 apoptosis via down-regulation of XIAP. target gene hsa-mir-137 "Carcinoma, Lung, Non-Small-Cell" 28239819 MiR-137 and its target TGFA modulate cell growth and tumorigenesis of non-small cell lung cancer. target gene hsa-mir-29c "Adenocarcinoma, Lung" 28241836 MicroRNA-29c functions as a tumor suppressor by targeting VEGFA in lung adenocarcinoma. target gene hsa-mir-520e "Carcinoma, Lung, Non-Small-Cell" 28242196 MicroRNA-520e suppresses non-small-cell lung cancer cell growth by targeting Zbtb7a-mediated Wnt signaling pathway. target gene hsa-mir-124 Glioblastoma 28242198 miR-124 suppresses glioblastoma growth and potentiates chemosensitivity by inhibiting AURKA. target gene hsa-mir-130 Obesity 28242765 APCDD1 positively regulates adipogenic differentiation and that its down-regulation by miR-130 during DIO may contribute to impaired adipogenic differentiation and obesity-related metabolic disease target gene hsa-mir-98 "Carcinoma, Hepatocellular" 28244848 MicroRNA-98-5p Inhibits Cell Proliferation and Induces Cell Apoptosis in Hepatocellular Carcinoma via Targeting IGF2BP1. target gene hsa-mir-543 "Carcinoma, Prostate" 28245474 MiR-543 Promotes Proliferation and Epithelial-Mesenchymal Transition in Prostate Cancer via Targeting RKIP. target gene hsa-mir-155 Wound Healing 28247149 miR-155 promotes cutaneous wound healing through enhanced keratinocytes migration by MMP-2. target gene hsa-mir-20b Viral Myocarditis 28247213 MicroRNA-20b suppresses the expression of ZFP-148 in viral myocarditis. target gene hsa-mir-98 Endomyocardial Fibrosis 28251559 MicroRNA-98 inhibits TGF-¦Â1-induced differentiation and collagen production of cardiac fibroblasts by targeting TGFBR1. target gene hsa-mir-15b Coronary Artery Disease 28254819 MiR-15b-5p Regulates Collateral Artery Formation by Targeting AKT3 (Protein Kinase B-3). target gene hsa-mir-19a "Carcinoma, Colon" 28257633 miR-19a promotes colorectal cancer proliferation and migration by targeting TIA1. target gene hsa-mir-133a Atherosclerosis 28257760 Induction of MiR133a expression by IL-19 targets LDLRAP1 and reduces oxLDL uptake in VSMC. target gene hsa-mir-185 Keloid 28259900 MicroRNA?185 regulates transforming growth factor?¦Â1 and collagen?1 in hypertrophic scar fibroblasts. target gene hsa-mir-7 "Carcinoma, Pancreatic" 28259961 MicroRNA-7 functions as a tumor-suppressor gene by regulating ILF2 in pancreatic carcinoma. target gene hsa-mir-30a "Carcinoma, Lung, Non-Small-Cell" 28259977 miR-30a radiosensitizes non-small cell lung cancer by targeting ATF1 that is involved in the phosphorylation of ATM. target gene hsa-mir-365 Glioma 28260020 "MicroRNA-365 inhibits proliferation, migration and invasion of glioma by targeting PIK3R3." target gene hsa-mir-134 "Carcinoma, Gastric" 28260021 MicroRNA-134 suppresses cell proliferation in gastric cancer cells via targeting of GOLPH3. target gene hsa-mir-125b "Carcinoma, Nasopharyngeal" 28260044 microRNA-125b reverses the multidrug resistance of nasopharyngeal carcinoma cells via targeting of Bcl-2. target gene hsa-mir-126 "Carcinoma, Gastric" 28260063 ADAM9 functions as a promoter of gastric cancer growth which is negatively and post-transcriptionally regulated by miR-126. target gene hsa-mir-125b Osteoarthritis 28260078 Upregulation of microRNA-125b-5p is involved in the pathogenesis of osteoarthritis by downregulating SYVN1. target gene hsa-mir-1271 "Carcinoma, Lung, Non-Small-Cell" 28260088 Foxk2 inhibits non-small cell lung cancer epithelial-mesenchymal transition and proliferation through the repression of different key target genes. target gene hsa-mir-92a Osteosarcoma 28260104 miR-92a promotes tumor growth of osteosarcoma by targeting PTEN/AKT signaling pathway. target gene hsa-mir-21 Osteosarcoma 28260111 miR-21-5p may be associated with metastasis via target genes target gene hsa-mir-9 "Leukemia, Myeloid, Chronic" 28260112 miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1. target gene hsa-mir-199a "Carcinoma, Hepatocellular" 28261837 MiR-199a-5p suppresses tumorigenesis by targeting clathrin heavy chain in hepatocellular carcinoma. target gene hsa-mir-23b "Carcinoma, Hepatocellular" 28262617 microRNA-23b suppresses epithelial-mesenchymal transition (EMT) and metastasis in hepatocellular carcinoma via targeting Pyk2. target gene hsa-mir-377 "Squamous Cell Carcinoma, Oral" 28267394 Downregulation of miR-377 Promotes Oral Squamous Cell Carcinoma Growth and Migration by Targeting HDAC9. target gene hsa-mir-1 "Carcinoma, Bladder" 28268231 "MiR-1-3p Suppresses the Proliferation, Invasion and Migration of Bladder Cancer Cells by Up-Regulating SFRP1 Expression." target gene hsa-mir-31 "Carcinoma, Hepatocellular" 28269758 MicroRNA31-NDRG3 regulation axes are essential for hepatocellular carcinoma survival and drug resistance. target gene hsa-mir-124 Glioma 28272711 Down-regulation of miR-124 target protein SCP-1 inhibits neuroglioma cell migration. target gene hsa-mir-875 "Carcinoma, Prostate" 28274892 miR-875-5p counteracts epithelial-to-mesenchymal transition and enhances radiation response in prostate cancer through repression of the EGFR-ZEB1 axis. target gene hsa-mir-34a Osteosarcoma 28275089 "The miR-34a/STMN1/¦ÂIII-tubulin axis maintains the microtubule cytoskeleton in osteosarcoma, and combining miR-34a with microtubule inhibitors can be investigated as a novel therapeutic strategy" target gene hsa-mir-142 Inflammation 28275790 MiR-142-3p inhibits lipopolysaccharide-induced inflammatory response in human periodontal ligament cells through targeting IRAK1. target gene hsa-mir-422a Glioma 28277190 miR-422a Inhibits Glioma Proliferation and Invasion by Targeting IGF1 and IGF1R. target gene hsa-mir-202 "Squamous Cell Carcinoma, Esophageal" 28277193 miR-202 Promotes Cell Apoptosis in Esophageal Squamous Cell Carcinoma by Targeting HSF2. target gene hsa-mir-146a Graves Disease 28278511 Mechanism of MicroRNA-146a/Notch2 Signaling Regulating IL-6 in Graves Ophthalmopathy. target gene hsa-mir-181a Osteoarthritis 28280258 miR-181a Modulates Chondrocyte Apoptosis by Targeting Glycerol-3-Phosphate Dehydrogenase 1-Like Protein (GPD1L) in Osteoarthritis. target gene hsa-mir-21 "Diabetes Mellitus, Type 1" 28280903 MicroRNA 21 targets BCL2 mRNA to increase apoptosis in rat and human beta cells. target gene hsa-mir-200a Pancreatic Neoplasms 28281184 TGF-¦Â1-miR-200a-PTEN induces epithelial-mesenchymal transition and fibrosis of pancreatic stellate cells. target gene hsa-mir-93 Neuropathic Pain 28284149 MicroRNA-93 alleviates neuropathic pain through targeting signal transducer and activator of transcription 3. target gene hsa-mir-181d Glioblastoma 28286260 miR-181d/MALT1 regulatory axis attenuates mesenchymal phenotype through NF-¦ÊB pathways in glioblastoma. target gene hsa-mir-133a "Carcinoma, Pancreatic" 28286270 "USP39, a direct target of microRNA-133a, promotes progression of pancreatic cancer via the AKT pathway." target gene hsa-mir-181a "Carcinoma, Breast" 28288641 "SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5p, miR-30e-5p/TUSC3 axis." target gene hsa-mir-30e "Carcinoma, Breast" 28288641 "SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5p, miR-30e-5p/TUSC3 axis." target gene hsa-mir-146a Sepsis 28288804 MiR-146a potentially promotes IVIg-mediated inhibition of TLR4 signaling in LPS-activated human monocytes. target gene hsa-mir-214 "Carcinoma, Oral" 28290615 MiR-214 regulates oral cancer KB cell apoptosis through targeting RASSF5. target gene hsa-mir-30a Idiopathic Pulmonary Fibrosis 28294974 miR-30a as Potential Therapeutics by Targeting TET1 through Regulation of Drp-1 Promoter Hydroxymethylation in Idiopathic Pulmonary Fibrosis. target gene hsa-mir-182 "Leukemia, Promyelocytic, Acute" 28298075 Inducing cell proliferative prevention in human acute promyelocytic leukemia by miR-182 inhibition through modulation of CASP9 expression. target gene hsa-mir-146a Diabetes Mellitus 28301595 miR-146a regulates glucose induced upregulation of inflammatory cytokines extracellular matrix proteins in the retina and kidney in diabetes. target gene hsa-mir-495 "Carcinoma, Lung, Small-Cell" 28302484 TSPAN12 promotes chemoresistance and proliferation of SCLC under the regulation of miR-495. target gene hsa-mir-146a Osteoarthritis 28314786 Effects of microRNA-146a on the proliferation and apoptosis of human osteoarthritis chondrocytes by targeting TRAF6 through the NF-¦ÊB signalling pathway. target gene hsa-mir-519 "Carcinoma, Nasopharyngeal" 28315691 miR-519 suppresses nasopharyngeal carcinoma cell proliferation by targeting oncogene URG4/URGCP. target gene hsa-mir-186 "Carcinoma, Lung, Non-Small-Cell" 28317368 MiR-186 Inhibited Migration of NSCLC via Targeting cdc42 and Effecting EMT Process. target gene hsa-mir-218 "Carcinoma, Gastric" 28323002 miR-218 inhibited tumor angiogenesis by targeting ROBO1 in gastric cancer. target gene hsa-mir-302b Glioma 28323865 The microRNA-302b-inhibited insulin-like growth factor-binding protein 2 signaling pathway induces glioma cell apoptosis by targeting nuclear factor IA. target gene hsa-mir-181b Cardiovascular Diseases [unspecific] 28323879 miR-181b regulates vascular stiffness age dependently in part by regulating TGF-¦Â signaling. target gene hsa-mir-199 "Carcinoma, Bladder" 28324890 Regulation of ITGA3 by the dual-stranded microRNA-199 family as a potential prognostic marker in bladder cancer. target gene hsa-mir-27a Gastric Neoplasms 28327189 MicroRNA-27a contributes to the malignant behavior of gastric cancer cells by directly targeting PH domain and leucine-rich repeat protein phosphatase 2. target gene hsa-mir-3908 "Carcinoma, Breast" 28327197 Lipid raft-mediated miR-3908 inhibition of migration of breast cancer cell line MCF-7 by regulating the interactions between AdipoR1 and Flotillin-1. target gene hsa-mir-488 Melanoma 28328082 MicroRNA-488-3p sensitizes malignant melanoma cells to cisplatin by targeting PRKDC. target gene hsa-mir-9 Atherosclerosis 28334721 MicroRNA-9 Inhibits NLRP3 Inflammasome Activation in Human Atherosclerosis Inflammation Cell Models through the JAK1/STAT Signaling Pathway. target gene hsa-mir-122 Gastric Neoplasms 28337380 MicroRNA-122 inhibits proliferation and invasion in gastric cancer by targeting CREB1. target gene hsa-mir-373 "Squamous Cell Carcinoma, Tongue" 28337453 miR-373-3p Targets DKK1 to Promote EMT-Induced Metastasis via the Wnt/¦Â-Catenin Pathway in Tongue Squamous Cell Carcinoma. target gene hsa-mir-370 Cerebral Aneurysm 28338184 MicroRNA-370-3p inhibits human vascular smooth muscle cell proliferation via targeting KDR/AKT signaling pathway in cerebral aneurysm. target gene hsa-mir-146a Lupus Nephritis 28338190 The role of miR-146a in modulating TRAF6-induced inflammation during lupus nephritis. target gene hsa-mir-155 Neoplasms [unspecific] 28338203 "MiR-155 regulates oral squamous cell carcinoma Tca8113 cell proliferation, cycle, and apoptosis via regulating p27Kip1." target gene hsa-mir-374b "Carcinoma, Colon" 28339062 p53/microRNA-374b/AKT1 regulates colorectal cancer cell apoptosis in response to DNA damage. target gene hsa-mir-140 Osteosarcoma 28341864 MicroRNA-140-5p regulates osteosarcoma chemoresistance by targeting HMGN5 and autophagy. target gene hsa-mir-206 Atherosclerosis 28342807 Myocardin inhibited the gap protein connexin 43 via promoted miR-206 to regulate vascular smooth muscle cell phenotypic switch. target gene hsa-mir-29a "Carcinoma, Hepatocellular" 28342862 miR-29a suppresses growth and migration of hepatocellular carcinoma by regulating CLDN1. target gene hsa-mir-448 Multiple Sclerosis 28342869 MicroRNA-448 promotes multiple sclerosis development through induction of Th17 response through targeting protein tyrosine phosphatase non-receptor type 2 (PTPN2). target gene hsa-mir-373 Osteoarthritis 28343378 Adipose-Derived Stem Cells Suppress Inflammation Induced by IL-1¦Â through Down-Regulation of P2X7R Mediated by miR-373 in Chondrocytes of Osteoarthritis. target gene hsa-mir-29c "Carcinoma, Lung" 28345453 Tumor suppressor miR-29c regulates radioresistance in lung cancer cells. target gene hsa-mir-195 Colorectal Carcinoma 28345460 Coactivator-associated arginine methyltransferase 1 promotes cell growth and is targeted by microRNA-195-5p in human colorectal cancer. target gene hsa-mir-590 "Carcinoma, Prostate" 28345464 MicroRNA-590-3p promotes cell proliferation and invasion by targeting inositol polyphosphate 4-phosphatase type II in human prostate cancer cells. target gene hsa-mir-21 Colorectal Carcinoma 28347230 Inhibition of microRNA-21 via locked nucleic acid-anti-miR suppressed metastatic features of colorectal cancer cells through modulation of programmed cell death 4. target gene hsa-mir-22 Colorectal Carcinoma 28347238 "The predicted target gene validation, function, and prognosis studies of miRNA-22 in colorectal cancer tissue." target gene hsa-mir-34a Colorectal Carcinoma 28348487 miR-34a mediates oxaliplatin resistance of colorectal cancer cells by inhibiting macroautophagy via transforming growth factor-¦Â/Smad4 pathway. target gene hsa-mir-200 "Carcinoma, Pancreatic" 28349057 Interleukin-9 Promotes Pancreatic Cancer Cells Proliferation and Migration via the miR-200a/Beta-Catenin Axis. target gene hsa-mir-200a "Carcinoma, Pancreatic" 28349057 Interleukin-9 Promotes Pancreatic Cancer Cells Proliferation and Migration via the miR-200a/Beta-Catenin Axis. target gene hsa-mir-145 "Carcinoma, Breast" 28349828 "Silencing of bach1 gene by small interfering RNA-mediation regulates invasive and expression level of miR-203, miR-145, matrix metalloproteinase-9, and CXCR4 receptor in MDA-MB-468 breast cancer cells." target gene hsa-mir-203 "Carcinoma, Breast" 28349828 "Silencing of bach1 gene by small interfering RNA-mediation regulates invasive and expression level of miR-203, miR-145, matrix metalloproteinase-9, and CXCR4 receptor in MDA-MB-468 breast cancer cells." target gene hsa-mir-590 "Carcinoma, Hepatocellular" 28349829 MiR-590-3p suppresses hepatocellular carcinoma growth by targeting TEAD1. target gene hsa-mir-203 "Carcinoma, Lung, Non-Small-Cell" 28350100 Overexpression of miR-203 increases the sensitivity of NSCLC A549/H460 cell lines to cisplatin by targeting Dickkopf-1. target gene hsa-mir-455 "Carcinoma, Prostate" 28350134 MicroRNA-455-3p functions as a tumor suppressor by targeting eIF4E in prostate cancer. target gene hsa-mir-15b "Squamous Cell Carcinoma, Tongue" 28350138 miR-15b inhibits cancer-initiating cell phenotypes and chemoresistance of cisplatin by targeting TRIM14 in oral tongue squamous cell cancer. target gene hsa-mir-613 Retinoblastoma 28351331 "MiR-613 suppresses retinoblastoma cell proliferation, invasion, and tumor formation by targeting E2F5." target gene hsa-mir-145 Pituitary Adenoma 28352194 MicroRNA-145 inhibits the activation of the mTOR signaling pathway to suppress the proliferation and invasion of invasive pituitary adenoma cells by targeting AKT3 in vivo and in vitro. target gene hsa-mir-302d "Carcinoma, Hepatocellular" 28352351 MicroRNA-302d downregulates TGFBR2 expression and promotes hepatocellular carcinoma growth and invasion. target gene hsa-mir-24 Glioblastoma 28352781 SOX7 inhibits tumor progression of glioblastoma and is regulated by miRNA-24. target gene hsa-mir-155 Biliary Atresia 28355202 MicroRNA-155 modulates bile duct inflammation by targeting the suppressor of cytokine signaling 1 in biliary atresia. target gene hsa-mir-532 "Carcinoma, Gastric" 28356225 miR-532 promoted gastric cancer migration and invasion by targeting NKD1. target gene hsa-mir-27 Adenovirus Infection 28356525 MicroRNA miR-27 Inhibits Adenovirus Infection by Suppressing the Expression of SNAP25 and TXN2. target gene hsa-mir-27a Adenovirus Infection 28356525 MicroRNA miR-27 Inhibits Adenovirus Infection by Suppressing the Expression of SNAP25 and TXN2. target gene hsa-mir-27b Adenovirus Infection 28356525 MicroRNA miR-27 Inhibits Adenovirus Infection by Suppressing the Expression of SNAP25 and TXN2. target gene hsa-mir-103a "Aortic Aneurysm, Abdominal" 28357407 Role of MicroRNA-103a Targeting ADAM10 in Abdominal Aortic Aneurysm. target gene hsa-mir-194 Melanoma 28358423 Circulating microRNA-194 regulates human melanoma cells via PI3K/AKT/FoxO3a and p53/p21 signaling pathway. target gene hsa-mir-200 Glioma 28362995 Targeting effect of microRNA on CD133 and its impact analysis on proliferation and invasion of glioma cells. target gene hsa-mir-200b Glioma 28362995 Targeting effect of microRNA on CD133 and its impact analysis on proliferation and invasion of glioma cells. target gene hsa-mir-199a "Carcinoma, Lung" 28363780 miR-199a-5p and miR-495 target GRP78 within UPR pathway of lung cancer. target gene hsa-mir-495 "Carcinoma, Lung" 28363780 miR-199a-5p and miR-495 target GRP78 within UPR pathway of lung cancer. target gene hsa-mir-19a "Carcinoma, Lung" 28364280 Oncogenic miR-19a and miR-19b co-regulate tumor suppressor MTUS1 to promote cell proliferation and migration in lung cancer. target gene hsa-mir-19b "Carcinoma, Lung" 28364280 Oncogenic miR-19a and miR-19b co-regulate tumor suppressor MTUS1 to promote cell proliferation and migration in lung cancer. target gene hsa-mir-29b Breast Neoplasms 28365400 MiRNA-29b suppresses tumor growth through simultaneously inhibiting angiogenesis and tumorigenesis by targeting Akt3. target gene hsa-mir-200a "Carcinoma, Hepatocellular" 28367241 MicroRNA-200a inhibits cell growth and metastasis by targeting Foxa2 in hepatocellular carcinoma. target gene hsa-mir-126 Obesity 28367267 Obesity Downregulates MicroRNA-126 Inducing Capillary Rarefaction in Skeletal Muscle: Effects of Aerobic Exercise Training. target gene hsa-mir-494 Spinal Cord Injuries 28368292 Long Coding RNA XIST Contributes to Neuronal Apoptosis through the Downregulation of AKT Phosphorylation and Is Negatively Regulated by miR-494 in Rat Spinal Cord Injury. target gene hsa-mir-294 "Carcinoma, Bladder" 28371605 MicroRNA-294 Promotes Cellular Proliferation and Motility through the PI3K/AKT and JAK/STAT Pathways by Upregulation of NRAS in Bladder Cancer. target gene hsa-mir-34 "Carcinoma, Prostate" 28373004 Natural killer cells suppress enzalutamide resistance and cell invasion in the castration resistant prostate cancer via targeting the androgen receptor splicing variant 7 (ARv7). target gene hsa-mir-449 "Carcinoma, Prostate" 28373004 Natural killer cells suppress enzalutamide resistance and cell invasion in the castration resistant prostate cancer via targeting the androgen receptor splicing variant 7 (ARv7). target gene hsa-mir-375 Colorectal Carcinoma 28374902 Impact of microRNA-375 and its target gene SMAD-7 polymorphism on susceptibility of colorectal cancer. target gene hsa-mir-363 Rheumatoid Arthritis 28376277 Dendritic Cells from Rheumatoid Arthritis Patient Peripheral Blood Induce Th17 Cell Differentiation via miR-363/Integrin ¦Áv/TGF-¦Â Axis. target gene hsa-let-7e "Carcinoma, Ovarian" 28376831 Let-7e sensitizes epithelial ovarian cancer to cisplatin through repressing DNA double strand break repair. target gene hsa-mir-874 "Carcinoma, Pancreatic" 28377226 Aquaporin 3 facilitates tumor growth in pancreatic cancer by modulating mTOR signaling. target gene hsa-mir-486 Aortic Valve Disease 28377507 miR-486 inhibits Smurf2 expression to augment the miR-204 down-regulation target gene hsa-mir-20a "Carcinoma, Hepatocellular" 28378640 Bioinformatics prediction and experimental validation of microRNA-20a targeting Cyclin D1 in hepatocellular carcinoma. target gene hsa-mir-125b "Carcinoma, Lung, Non-Small-Cell" 28378642 Targeting insulin-like growth factor-binding protein-3 by microRNA-125b promotes tumor invasion and poor outcomes in non-small-cell lung cancer. target gene hsa-mir-144 Influenza 28380049 miR-144 attenuates the host response to influenza virus by targeting the TRAF6-IRF7 signaling axis. target gene hsa-mir-181a Osteosarcoma 28381158 Triptolide inhibits the growth of osteosarcoma by regulating microRNA-181a via targeting PTEN gene in vivo and vitro. target gene hsa-mir-181d "Carcinoma, Pancreatic" 28381166 Downregulation of microRNA-181d had suppressive effect on pancreatic cancer development through inverse regulation of KNAIN2. target gene hsa-mir-146a Osteoarthritis 28383548 miR-146a facilitates osteoarthritis by regulating cartilage homeostasis via targeting Camk2d and Ppp3r2. target gene hsa-mir-200b "Carcinoma, Hepatocellular" 28383782 The miR-200b-ZEB1 circuit regulates diverse stemness of human hepatocellular carcinoma. target gene hsa-mir-138 "Carcinoma, Cervical" 28385388 MicroRNA-138 is a potential biomarker and tumor suppressor in human cervical carcinoma by reversely correlated with TCF3 gene. target gene hsa-mir-137 Glioblastoma 28386374 MicroRNA-137 inhibits growth of glioblastoma through EGFR suppression. target gene hsa-mir-370 "Carcinoma, Hepatocellular" 28387905 miRNA-370 acts as a tumor suppressor via the downregulation of PIM1 in hepatocellular carcinoma. target gene hsa-mir-181a Glioblastoma 28389242 Upregulation of miR-181a suppresses the formation of glioblastoma stem cells by targeting the Notch2 oncogene and correlates with good prognosis in patients with glioblastoma multiforme. target gene hsa-mir-125b Leukemia 28389358 MicroRNA-125b inhibits AML cells differentiation by directly targeting Fes. target gene hsa-mir-135a "Carcinoma, Hepatocellular" 28389526 Regulation of UDP-Glucuronosyltransferases UGT2B4 and UGT2B7 by MicroRNAs in Liver Cancer Cells. target gene hsa-mir-216b "Carcinoma, Hepatocellular" 28389526 Regulation of UDP-Glucuronosyltransferases UGT2B4 and UGT2B7 by MicroRNAs in Liver Cancer Cells. target gene hsa-mir-3664 "Carcinoma, Hepatocellular" 28389526 Regulation of UDP-Glucuronosyltransferases UGT2B4 and UGT2B7 by MicroRNAs in Liver Cancer Cells. target gene hsa-mir-410 "Carcinoma, Hepatocellular" 28389526 Regulation of UDP-Glucuronosyltransferases UGT2B4 and UGT2B7 by MicroRNAs in Liver Cancer Cells. target gene hsa-mir-181d Glioblastoma 28389653 Identification of IGF-1-enhanced cytokine expressions targeted by miR-181d in glioblastomas via an integrative miRNA/mRNA regulatory network analysis. target gene hsa-mir-21 Acute Cerebral Infarction 28389999 Effects of microRNA-21 on Nerve Cell Regeneration and Neural Function Recovery in Diabetes Mellitus Combined with Cerebral Infarction Rats by Targeting PDCD4. target gene hsa-mir-661 Osteosarcoma 28391262 MicroRNA-661 Enhances TRAIL or STS Induced Osteosarcoma Cell Apoptosis by Modulating the Expression of Cytochrome c1. target gene hsa-mir-143 "Carcinoma, Prostate" 28391351 Curcumin inhibits prostate cancer by targeting PGK1 in the FOXD3/miR-143 axis. target gene hsa-mir-206 "Carcinoma, Breast" 28391353 WBP2 modulates G1/S transition in ER+?breast cancer cells and is a direct target of miR-206. target gene hsa-mir-221 "Carcinoma, Lung, Non-Small-Cell" 28392366 miRNA-221 acts as an oncogenic role by directly targeting TIMP2 in non-small-cell lung carcinoma. target gene hsa-mir-145 "Carcinoma, Breast" 28393176 miR-145 inhibits proliferation and migration of breast cancer cells by directly or indirectly regulating TGF-¦Â1 expression. target gene hsa-mir-107 "Squamous Cell Carcinoma, Esophageal" 28393193 miR-107 functions as a tumor suppressor in human esophageal squamous cell carcinoma and targets Cdc42. target gene hsa-mir-187 "Carcinoma, Lung, Non-Small-Cell" 28393200 MicroRNA-187 modulates epithelial-mesenchymal transition by targeting PTRF in non-small cell lung cancer. target gene hsa-mir-539 "Carcinoma, Hepatocellular" 28393215 miR-539 inhibits FSCN1 expression and suppresses hepatocellular carcinoma migration and invasion. target gene hsa-mir-124 Glioma 28393219 Inhibition of the Hedgehog signaling pathway suppresses cell proliferation by regulating the Gli2/miR-124/AURKA axis in human glioma cells. target gene hsa-mir-27a "Carcinoma, Nasopharyngeal" 28393229 Dysregulated miR-27a-3p promotes nasopharyngeal carcinoma cell proliferation and migration by targeting Mapk10. target gene hsa-mir-329 "Carcinoma, Cervical" 28393232 "MicroRNA-329-3p targets MAPK1 to suppress cell proliferation, migration and invasion in cervical cancer." target gene hsa-mir-130a Neoplasms [unspecific] 28393235 Epigenetic silencing of miR-130a ameliorates hemangioma by targeting tissue factor pathway inhibitor?2 through FAK/PI3K/Rac1/mdm2 signaling. target gene hsa-mir-10b Glioblastoma 28393237 "MicroRNA-10b mediates TGF-¦Â1-regulated glioblastoma proliferation, migration and epithelial-mesenchymal transition." target gene hsa-mir-597 "Carcinoma, Breast" 28393251 "miR-597 inhibits breast cancer cell proliferation, migration and invasion through FOSL2." target gene hsa-mir-4417 "Carcinoma, Hepatocellular" 28394882 miR-4417 Targets Tripartite Motif-Containing 35 (TRIM35) and Regulates Pyruvate Kinase Muscle 2 (PKM2) Phosphorylation to Promote Proliferation and Suppress Apoptosis in Hepatocellular Carcinoma Cells. target gene hsa-mir-9 Breast Neoplasms 28397066 "MicroRNA-9 promotes the proliferation, migration, and invasion of breast cancer cells via down-regulating FOXO1." target gene hsa-mir-150 Psoriasis 28399173 MiR-150 regulates human keratinocyte proliferation in hypoxic conditions through targeting HIF-1¦Á and VEGFA: Implications for psoriasis treatment. target gene hsa-mir-34a "Carcinoma, Gastric" 28399871 IGF2BP3 functions as a potential oncogene and is a crucial target of miR-34a in gastric carcinogenesis. target gene hsa-mir-18a "Carcinoma, Hepatocellular" 28399983 microRNA-18a Promotes Cell Migration and Invasion Through Inhibiting Dicer l Expression in Hepatocellular Carcinoma In Vitro. target gene hsa-mir-146a Neoplasms [unspecific] 28401709 The role of microRNA-93 regulating angiopoietin2 in the formation of malignant pleural effusion. target gene hsa-mir-93 Neoplasms [unspecific] 28401709 The role of microRNA-93 regulating angiopoietin2 in the formation of malignant pleural effusion. target gene hsa-mir-210 Cervical Neoplasms 28401751 Down-Regulation of MicroRNA-210 Confers Sensitivity towards 1'S-1'-Acetoxychavicol Acetate (ACA) in Cervical Cancer Cells by Targeting SMAD4. target gene hsa-mir-200 "Carcinoma, Lung, Non-Small-Cell" 28405157 Decitabine reverses TGF-¦Â1-induced epithelial-mesenchymal transition in non-small-cell lung cancer by regulating miR-200/ZEB axis. target gene hsa-mir-30a "Carcinoma, Lung, Non-Small-Cell" 28405690 MicroRNA-30a-5p suppresses epithelial-mesenchymal transition by targeting profilin-2 in high invasive non-small cell lung cancer cell lines. target gene hsa-mir-381 Osteosarcoma 28406476 "WISP-1 enhances VEGF-A expression and angiogenesis through the FAK/JNK/HIF-1¦Á signaling pathways, as well as via down-regulation of miR-381 expression" target gene hsa-mir-137 Breast Neoplasms 28407692 MicroRNA-137 inhibits BMP7 to enhance the epithelial-mesenchymal transition of breast cancer cells. target gene hsa-mir-18a "Adenocarcinoma, Colon" 28408657 Negative Regulation of Human Pregnane X Receptor by MicroRNA-18a-5p: Evidence for Suppression of MicroRNA-18a-5p Expression by Rifampin and Rilpivirine. target gene hsa-mir-106b "Carcinoma, Hepatocellular" 28410209 MiR-106b inhibitors sensitize TRAIL-induced apoptosis in hepatocellular carcinoma through increase of death receptor 4. target gene hsa-mir-21 Glioblastoma 28410224 Glioma stem cells-derived exosomes promote the angiogenic ability of endothelial cells through miR-21/VEGF signal. target gene hsa-mir-302c "Carcinoma, Renal Cell" 28412750 microRNA-302c-3p inhibits renal cell carcinoma cell proliferation by targeting Grb2-associated binding 2 (Gab2). target gene hsa-mir-98 "Carcinoma, Lung, Non-Small-Cell" 28415380 miR-98 inhibits expression of TWIST to prevent progression of non-small cell lung cancers. target gene hsa-mir-330 "Carcinoma, Breast" 28419078 Targeting of CCBE1 by miR-330-3p in human breast cancer promotes metastasis. target gene hsa-mir-193a "Carcinoma, Prostate" 28422308 Androgen receptor-regulated miRNA-193a-3p targets AJUBA to promote prostate cancer cell migration. target gene hsa-mir-16 Myocardial Infarction 28423616 Suppression of microRNA-16 protects against acute myocardial infarction by reversing beta2-adrenergic receptor down-regulation in rats. target gene hsa-mir-223 Pancreatic Neoplasms 28423622 HnRNPK/miR-223/FBXW7 feedback cascade promotes pancreatic cancer cell growth and invasion. target gene hsa-mir-126 Atherosclerosis 28425867 MiR-126 activates the endothelial production of a chemokine CXCL12 via self-multiplying feedback loop to promote re-endothelialization and support lesion stability target gene hsa-mir-299 Neoplasms [unspecific] 28426762 Human microRNA-299-3p decreases invasive behavior of cancer cells by downregulation of Oct4 expression and causes apoptosis. target gene hsa-mir-142 "Carcinoma, Lung, Non-Small-Cell" 28427045 MiR-142-3p Overexpression Increases Chemo-Sensitivity of NSCLC by Inhibiting HMGB1-Mediated Autophagy. target gene hsa-mir-494 Intervertebral Disc Degeneration 28427186 MicroRNA-494 promotes ECM degradation and apoptosis of degenerative human NP cells by directly targeting SOX9 target gene hsa-mir-146b "Carcinoma, Thyroid, Follicular" 28427206 "miR-146a and miR-146b promote proliferation, migration and invasion of follicular thyroid carcinoma via inhibition of ST8SIA4." target gene hsa-mir-205 Endometrial Neoplasms 28427207 miR-205 inhibits cell growth by targeting AKT-mTOR signaling in progesterone-resistant endometrial cancer Ishikawa cells. target gene hsa-mir-218 "Carcinoma, Lung, Non-Small-Cell" 28429357 Inhibition of pulmonary carcinoma proliferation or metastasis of miR-218 via down-regulating CDCP1 expression. target gene hsa-mir-148a Breast Neoplasms 28430743 MicroRNA-148a promotes apoptosis and suppresses growth of breast cancer cells by targeting B-cell lymphoma 2. target gene hsa-mir-9 Glioma 28430789 MiR-9-3p augments apoptosis induced by H2O2 through down regulation of Herpud1 in glioma. target gene hsa-mir-429 Fibrosarcoma 28432002 miR-429 inhibits metastasis by targeting KIAA0101 in Soft Tissue Sarcoma. target gene hsa-mir-590 Colorectal Carcinoma 28433598 "MiR-590-5p, a density-sensitive microRNA, inhibits tumorigenesis by targeting YAP1 in colorectal cancer." target gene hsa-mir-146a Diabetic Retinopathy 28433754 miR-146a suppresses STAT3/VEGF pathways and reduces apoptosis through IL-6 signaling in primary human retinal microvascular endothelial cells in high glucose conditions. target gene hsa-let-7b Nervous System Diseases [unspecific] 28436683 Dexmedetomidine Protects PC12 Cells from Lidocaine-Induced Cytotoxicity Through Downregulation of COL3A1 Mediated by miR-let-7b. target gene hsa-mir-217 "Carcinoma, Breast, Triple Negative" 28437471 "miR-217 inhibits triple-negative breast cancer cell growth, migration, and invasion through targeting KLF5." target gene hsa-mir-124 Pediatric Ependymoma 28437838 Prognostic relevance of miR-124-3p and its target TP53INP1 in pediatric ependymoma. target gene hsa-mir-200a "Carcinoma, Hepatocellular" 28440466 miR-200a targets Gelsolin: A novel mechanism regulating secretion of microvesicles in hepatocellular carcinoma cells. target gene hsa-mir-200a "Carcinoma, Breast" 28440475 "A nine-miRNA signature as a potential diagnostic marker for breast carcinoma: An integrated study of 1,110 cases." target gene hsa-mir-15a Ischemia-Reperfusion Injury 28440490 MicroRNA-15a inhibition protects against hypoxia/reoxygenation-induced apoptosis of cardiomyocytes by targeting mothers against decapentaplegic homolog 7. target gene hsa-mir-1185 Atherosclerosis 28441650 MicroRNA-1185 Induces Endothelial Cell Apoptosis by Targeting UVRAG and KRIT1. target gene hsa-mir-1185 Atherosclerosis 28441665 MicroRNA-1185 Promotes Arterial Stiffness though Modulating VCAM-1 and E-Selectin Expression. target gene hsa-mir-221 "Carcinoma, Hepatocellular" 28442344 miR-221 regulates CD44 in hepatocellular carcinoma through the PI3K-AKT-mTOR pathway. target gene hsa-mir-30a Diabetic Cataract 28442786 MicroRNA-30a Regulation of Epithelial-Mesenchymal Transition in Diabetic Cataracts Through Targeting SNAI1. target gene hsa-mir-1202 Glioma 28443461 MiR-1202 functions as a tumor suppressor in glioma cells by targeting Rab1A. target gene hsa-mir-30c "Carcinoma, Lung, Non-Small-Cell" 28443468 Curcumin increases the sensitivity of Paclitaxel-resistant NSCLC cells to Paclitaxel through microRNA-30c-mediated MTA1 reduction. target gene hsa-mir-590 "Carcinoma, Breast" 28443471 Suppressing the molecular signaling pathways involved in inflammation and cancer in breast cancer cell lines MDA-MB-231 and MCF-7 by miR-590. target gene hsa-mir-26a Colorectal Carcinoma 28443472 MiR-26a downregulates retinoblastoma in colorectal cancer. target gene hsa-mir-340 Osteosarcoma 28443990 MicroRNA-340-5p modulates cisplatin resistance by targeting LPAAT¦Â in osteosarcoma. target gene hsa-mir-125a "Carcinoma, Hepatocellular" 28445974 "Lowered expression of microRNA-125a-5p in human hepatocellular carcinoma and up-regulation of its oncogenic targets sirtuin-7, matrix metalloproteinase-11, and c-Raf." target gene hsa-mir-181a Gastric Neoplasms 28447759 "miR-181a modulates proliferation, migration and autophagy in AGS gastric cancer cells and downregulates MTMR3." target gene hsa-mir-193a Neoplasms [unspecific] 28449010 "Excess of a Rassf1-targeting microRNA, miR-193a-3p, perturbs cell division fidelity." target gene hsa-mir-31 "Squamous Cell Carcinoma, Skin or Unspecific" 28454216 MicroRNA-31 functions as an oncogenic microRNA in cutaneous squamous cell carcinoma cells by targeting RhoTBT1. target gene hsa-mir-29a "Fatty Liver, Non-Alcoholic" 28454323 MicroRNA-29a/b/c targets iNOS and is involved in protective remote ischemic preconditioning in an ischemia-reperfusion rat model of non-alcoholic fatty liver disease. target gene hsa-mir-29b "Fatty Liver, Non-Alcoholic" 28454323 MicroRNA-29a/b/c targets iNOS and is involved in protective remote ischemic preconditioning in an ischemia-reperfusion rat model of non-alcoholic fatty liver disease. target gene hsa-mir-29c "Fatty Liver, Non-Alcoholic" 28454323 MicroRNA-29a/b/c targets iNOS and is involved in protective remote ischemic preconditioning in an ischemia-reperfusion rat model of non-alcoholic fatty liver disease. target gene hsa-mir-150 Osteosarcoma 28454380 "miR-150 is downregulated in osteosarcoma and suppresses cell proliferation, migration and invasion by targeting ROCK1." target gene hsa-mir-409 "Carcinoma, Breast" 28459205 MicroRNA-409-5p is upregulated in breast cancer and its downregulation inhibits cancer development through downstream target of RSU1. target gene hsa-mir-200c "Carcinoma, Nasopharyngeal" 28459373 MicroRNA-200c plays an oncogenic role in nasopharyngeal carcinoma by targeting PTEN. target gene hsa-mir-181b Glioblastoma 28459461 MiR-181b modulates EGFR-dependent VCAM-1 expression and monocyte adhesion in glioblastoma. target gene hsa-mir-21 Atherosclerosis 28460288 Thrombin-activated platelet-derived exosomes regulate endothelial cell expression of ICAM-1 via microRNA-223 during the thrombosis-inflammation response. target gene hsa-mir-223 Atherosclerosis 28460288 Thrombin-activated platelet-derived exosomes regulate endothelial cell expression of ICAM-1 via microRNA-223 during the thrombosis-inflammation response. target gene hsa-mir-19b "Leukemia, Myeloid, Chronic" 28461114 miR-17-92 promotes leukemogenesis in chronic myeloid leukemia via targeting A20 and activation of NF-¦ÊB signaling. target gene hsa-mir-155 "Colitis, Ulcerative" 28461115 MiR-155 contributes to Th17 cells differentiation in dextran sulfate sodium (DSS)-induced colitis mice via Jarid2. target gene hsa-mir-1228 "Carcinoma, Gastric" 28465246 microRNA-1228? impairs the pro-angiogenic activity of gastric cancer cells by targeting macrophage migration inhibitory factor. target gene hsa-mir-145 Obstructive Sleep Apnea 28465478 Chronic obstructive sleep apnea promotes aortic remodeling in canines through miR-145/Smad3 signaling pathway. target gene hsa-mir-133a "Carcinoma, Colon" 28466778 miR-133a acts as a tumor suppressor in colorectal cancer by targeting eIF4A1. target gene hsa-mir-1 Colorectal Carcinoma 28471448 MiR-1 suppresses tumor cell proliferation in colorectal cancer by inhibition of Smad3-mediated tumor glycolysis. target gene hsa-mir-19a Osteosarcoma 28475001 MiR-19a regulates the cell growth and apoptosis of osteosarcoma stem cells by targeting PTEN. target gene hsa-mir-493 Melanoma 28475006 Downregulation of miR-493 promoted melanoma proliferation by suppressing IRS4 expression. target gene hsa-mir-34a "Leukemia, Myeloid, Acute" 28478444 MiR-34a Promotes Apoptosis and Inhibits Autophagy by Targeting HMGB1 in Acute Myeloid Leukemia Cells. target gene hsa-mir-1301 Prostate Neoplasms 28483517 MicroRNA-1301 suppresses tumor cell migration and invasion by targeting the p53/UBE4B pathway in multiple human cancer cells. target gene hsa-mir-34a Atherosclerosis 28485501 miR-34a Targets HDAC1-Regulated H3K9 Acetylation on Lipid Accumulation Induced by Homocysteine in Foam Cells. target gene hsa-mir-146a Thyroid-Associated Ophthalmopathy 28485799 Decreased microRNA-146a in CD4+T cells promote ocular inflammation in thyroid-associated ophthalmopathy by targeting NUMB. target gene hsa-mir-223 Inflammatory Bowel Diseases 28487310 Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. target gene hsa-mir-23b Colorectal Carcinoma 28487386 "our results define a critical function for miR-23b, which, by targeting LGR5, contributes to overpopulation of ALDH+ CSCs and colorectal cancer" target gene hsa-mir-195 "Carcinoma, Esophageal" 28487599 miR-195 Regulates Proliferation and Apoptosis through Inhibiting the mTOR/p70s6k Signaling Pathway by Targeting HMGA2 in Esophageal Carcinoma Cells. target gene hsa-mir-124 "Carcinoma, Lung, Non-Small-Cell" 28488541 MicroRNA-124 suppresses proliferation and glycolysis in non-small cell lung cancer cells by targeting AKT-GLUT1/HKII. target gene hsa-mir-106b Gastric Neoplasms 28489839 Deregulation of microRNAs in gastric cancer: up regulation by miR-21 and miR-106. target gene hsa-let-7a Psoriasis 28494466 Let-7a Inhibits T-Cell Proliferation and IFN-¦Ã Secretion by Down-Regulating STAT3 Expression in Patients with Psoriasis. target gene hsa-mir-21 Atrial Fibrillation 28495464 MicroRNA-21 via Dysregulation of WW Domain-Containing Protein 1 Regulate Atrial Fibrosis in Atrial Fibrillation. target gene hsa-mir-21 "Carcinoma, Cervical" 28495512 Modulation of CASC2/miR-21/PTEN pathway sensitizes cervical cancer to cisplatin. target gene hsa-mir-16 Glioblastoma 28497156 Tumor suppressors microRNA-302d and microRNA-16 inhibit human glioblastoma multiforme by targeting NF-¦ÊB and FGF2. target gene hsa-mir-302d Glioblastoma 28497156 Tumor suppressors microRNA-302d and microRNA-16 inhibit human glioblastoma multiforme by targeting NF-¦ÊB and FGF2. target gene hsa-mir-15 "Carcinoma, Lung, Non-Small-Cell" 28498424 MicroRNA-15b promotes proliferation and invasion of non?small cell lung carcinoma cells by directly targeting TIMP2. target gene hsa-mir-24-1 Liver Neoplasms 28499244 MicroRNA-24-1 suppresses mouse hepatoma cell invasion and metastasis via directly targeting O-GlcNAc transferase. target gene hsa-mir-375 "Squamous Cell Carcinoma, Head and Neck" 28499703 miR-375 Regulates Invasion-Related Proteins Vimentin and L-Plastin. target gene hsa-mir-140 Spinal Cord Injuries 28501777 MiR-140/BDNF axis regulates normal human astrocyte proliferation and LPS-induced IL-6 and TNF-¦Á secretion. target gene hsa-mir-874 "Carcinoma, Lung, Non-Small-Cell" 28501870 Long Non-Coding RNA XLOC_008466 Functions as an Oncogene in Human Non-Small Cell Lung Cancer by Targeting miR-874. target gene hsa-mir-181b Glioblastoma 28501897 MiR-181b modulates chemosensitivity of glioblastoma multiforme cells to temozolomide by targeting the epidermal growth factor receptor. target gene hsa-mir-183 "Carcinoma, Pancreatic" 28506766 "Effects of microRNA-183 on epithelial-mesenchymal transition, proliferation, migration, invasion and apoptosis in human pancreatic cancer SW1900 cells by targeting MTA1." target gene hsa-mir-21 "Hand, Foot And Mouth Disease" 28506791 Enterovirus 71-induced has-miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1. target gene hsa-mir-143 Breast Adenocarcinoma 28511343 Restoration of miR-143 expression could inhibit migration and growth of MDA-MB-468 cells through down-regulating the expression of invasion-related factors. target gene hsa-mir-513b Embryonal Testis Carcinoma 28512062 Hsa-miR-513b-5p suppresses cell proliferation and promotes P53 expression by targeting IRF2 in testicular embryonal carcinoma cells. target gene hsa-mir-130a Pulmonary Hypertension 28514291 Role of microRNA-130a in the pathogeneses of obstructive sleep apnea hypopnea syndrome-associated pulmonary hypertension by targeting the GAX gene. target gene hsa-mir-106b Breast Neoplasms 28518139 MiR-106b and miR-93 regulate cell progression by suppression of PTEN via PI3K/Akt pathway in breast cancer. target gene hsa-mir-29a "Carcinoma, Lung, Non-Small-Cell" 28521487 MicroRNA-29a functions as a potential tumor suppressor through directly targeting CDC42 in non-small cell lung cancer. target gene hsa-mir-181a Stroke 28522364 Inhibition of miR-181a protects female mice from transient focal cerebral ischemia by targeting astrocyte estrogen receptor-¦Á. target gene hsa-mir-34b Neuroblastoma 28525978 miRNA-34b is able to significantly downregulate DLL1 mRNA expression levels target gene hsa-mir-200a Melanoma 28526299 MiR-200a Regulates CDK4/6 Inhibitor Effect by Targeting CDK6 in Metastatic?Melanoma. target gene hsa-mir-195 "Carcinoma, Hepatocellular" 28529562 miR-195 inhibits cell proliferation via targeting AEG-1 in hepatocellular carcinoma. target gene hsa-mir-200b "Carcinoma, Endometrial" 28529604 "knockdown of DICER1 significantly downregulated miR-200b and let-7i, which may then regulate their targets SUZ12 and EZH2" target gene hsa-mir-16 Hypertension 28531963 MiR-19b and miR-16 cooperatively signaling target the regulator ADRA1A in Hypertensive heart disease. target gene hsa-mir-19b Hypertension 28531963 MiR-19b and miR-16 cooperatively signaling target the regulator ADRA1A in Hypertensive heart disease. target gene hsa-mir-145 Colorectal Carcinoma 28534337 MiR-145 inhibits drug resistance to Oxaliplatin in colorectal cancer cells through regulating G protein coupled receptor 98. target gene hsa-mir-204 Breast Neoplasms 28534958 miR-204 regulates the biological behavior of breast cancer MCF-7 cells by directly targeting FOXA1. target gene hsa-mir-34a "Squamous Cell Carcinoma, Esophageal" 28534990 Tumor suppressor microRNA-34a inhibits cell migration and invasion by targeting MMP-2/MMP-9/FNDC3B in esophageal squamous cell carcinoma. target gene hsa-mir-424 "Carcinoma, Lung, Non-Small-Cell" 28535539 MiR-424 Promotes Non-Small Cell Lung Cancer Progression and Metastasis through Regulating the Tumor Suppressor Gene TNFAIP1. target gene hsa-mir-181a "Carcinoma, Lung, Small-Cell" 28535543 MicroRNA-181a-5p Impedes IL-17-Induced Nonsmall Cell Lung Cancer Proliferation and Migration through Targeting VCAM-1. target gene hsa-mir-200b Melanoma 28535666 A miR-200b inhibitor induced the direct regulation of SOX-2 by DDX53 target gene hsa-mir-30b "Carcinoma, Renal Cell" 28536082 "MiR-30b-5p functions as a tumor suppressor in cell proliferation, metastasis and epithelial-to-mesenchymal transition by targeting G-protein subunit ¦Á-13 in renal cell carcinoma." target gene hsa-let-7 Liver Injury 28536261 The let-7/Lin28 axis regulates activation of hepatic stellate cells in alcoholic liver injury. target gene hsa-mir-126 "Carcinoma, Esophageal" 28536606 The crucial role of miR-126 on suppressing progression of esophageal cancer by targeting VEGF-A. target gene hsa-mir-210 Atherosclerosis 28536634 MicroRNA-210 induces endothelial cell apoptosis by directly targeting PDK1 in the setting of atherosclerosis. target gene hsa-mir-129 Neoplasms [unspecific] 28536635 "the regulation of NG2 expression underlies inflammation and hypoxia and is mediated by methyltransferases, transcription factors, including Sp1, paired box (Pax) 3 and Egr-1, and the microRNA miR129-2" target gene hsa-mir-19a Ileus 28537131 Acupuncture Ameliorates Postoperative Ileus via IL-6-miR-19a-KIT Axis to Protect Interstitial Cells of Cajal. target gene hsa-mir-20a "Carcinoma, Hepatocellular" 28537677 Targeting of miR-20a against CFLAR to potentiate TRAIL-induced apoptotic sensitivity in HepG2 cells. target gene hsa-mir-221 "Carcinoma, Hepatocellular" 28539268 MiR-221 mediates the epithelial-mesenchymal transition of hepatocellular carcinoma by targeting AdipoR1. target gene hsa-mir-29c Diabetes Mellitus 28539664 MiRNA-29c regulates the expression of inflammatory cytokines in diabetic nephropathy by targeting tristetraprolin. target gene hsa-mir-200c Colorectal Carcinoma 28543447 Fas signaling induces stemness properties in colorectal cancer by regulation of Bmi1. target gene hsa-mir-106b Preeclampsia 28545271 Effect of microRNA-106b on the invasion and proliferation of trophoblasts through targeting MMP-2. target gene hsa-mir-182 Breast Neoplasms 28546132 "Identification of direct target genes of miR-7, miR-9, miR-96, and miR-182 in the human breast cancer cell lines MCF-7 and MDA-MB-231." target gene hsa-mir-7 Breast Neoplasms 28546132 "Identification of direct target genes of miR-7, miR-9, miR-96, and miR-182 in the human breast cancer cell lines MCF-7 and MDA-MB-231." target gene hsa-mir-9 Breast Neoplasms 28546132 "Identification of direct target genes of miR-7, miR-9, miR-96, and miR-182 in the human breast cancer cell lines MCF-7 and MDA-MB-231." target gene hsa-mir-96 Breast Neoplasms 28546132 "Identification of direct target genes of miR-7, miR-9, miR-96, and miR-182 in the human breast cancer cell lines MCF-7 and MDA-MB-231." target gene hsa-mir-150 Osteosarcoma 28547952 Mir-150 Up-Regulates Glut1 and Increases Glycolysis in Osteosarcoma Cells target gene hsa-mir-26a Mycobacterium tuberculosis Infection 28558034 "MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBP¦Â regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection." target gene hsa-mir-143 Breast Neoplasms 28559978 miR-143-3p targeting LIM domain kinase 1 suppresses the progression of triple-negative breast cancer cells. target gene hsa-mir-146b Colorectal Carcinoma 28560062 "miR-146b-5p regulates cell growth, invasion, and metabolism by targeting PDHB in colorectal cancer." target gene hsa-mir-17 Neuroblastoma 28560387 Reciprocal antagonistic regulation of N-myc mRNA by miR?17 and the neuronal-specific RNA-binding protein HuD. target gene hsa-mir-20a Neuroblastoma 28560387 Reciprocal antagonistic regulation of N-myc mRNA by miR?17 and the neuronal-specific RNA-binding protein HuD. target gene hsa-mir-146a Gastric Neoplasms 28560435 MicroRNA-146a promotes gastric cancer cell apoptosis by targeting transforming growth factor ¦Â-activated kinase 1. target gene hsa-mir-155 "Carcinoma, Renal Cell, Clear-Cell" 28565840 Overexpression of miR-155 in clear-cell renal cell carcinoma and its oncogenic effect through targeting FOXO3a. target gene hsa-mir-125b "Carcinoma, Nasopharyngeal" 28569771 MiR-125b regulates proliferation and apoptosis of nasopharyngeal carcinoma by targeting A20/NF-¦ÊB signaling pathway. target gene hsa-mir-211 "Carcinoma, Breast, Triple Negative" 28571042 "MicroRNA-211-5p suppresses tumour cell proliferation, invasion, migration and metastasis in triple-negative breast cancer by directly targeting SETBP1." target gene hsa-mir-21 Neoplasms [unspecific] 28571917 Targeting miR-21 with Sophocarpine Inhibits Tumor Progression and Reverses Epithelial-Mesenchymal Transition in Head and Neck Cancer. target gene hsa-mir-124 "Leukemia, Lymphoblastic, Acute" 28578002 "MiR-124 contributes to glucocorticoid resistance in acute lymphoblastic leukemia by promoting proliferation, inhibiting apoptosis and targeting the glucocorticoid receptor." target gene hsa-mir-124 "Carcinoma, Nasopharyngeal" 28579809 miR-124 suppresses proliferation and invasion of nasopharyngeal carcinoma cells through the Wnt/¦Â-catenin signaling pathway by targeting Capn4. target gene hsa-mir-873 Glioma 28583401 miR-873 suppresses H9C2 cardiomyocyte proliferation by targeting GLI1. target gene hsa-mir-199b "Carcinoma, Hepatocellular" 28588321 MicroRNA-199b-5p attenuates TGF-¦Â1-induced epithelial-mesenchymal transition in hepatocellular carcinoma. target gene hsa-mir-18a Ovarian Neoplasms 28588697 MicroRNA-18a inhibits ovarian cancer growth via directly targeting TRIAP1 and IPMK. target gene hsa-mir-141 Glioma 28595907 miR-141-3p functions as a tumor suppressor modulating activating transcription factor 5 in glioma. target gene hsa-mir-150 Myocardial Infarction 28597963 miR-181a and miR-150 regulate dendritic cell immune inflammatory responses and cardiomyocyte apoptosis via targeting JAK1-STAT1/c-Fos pathway. target gene hsa-mir-181a Myocardial Infarction 28597963 miR-181a and miR-150 regulate dendritic cell immune inflammatory responses and cardiomyocyte apoptosis via targeting JAK1-STAT1/c-Fos pathway. target gene hsa-mir-126 Diabetes Mellitus 28598282 MicroRNA-126 Regulates Inflammatory Cytokine Secretion in Human Gingival Fibroblasts Under High Glucose via Targeting Tumor Necrosis Factor Receptor Associated Factor 6. target gene hsa-mir-155 Prostate Neoplasms 28599307 Morin promotes prostate cancer cells chemosensitivity to paclitaxel through miR-155/GATA3 axis. target gene hsa-mir-375 Esophageal Neoplasms 28599478 MicroRNA-375 suppresses esophageal cancer cell growth and invasion by repressing metadherin expression. target gene hsa-mir-630 "Carcinoma, Gastric" 28601080 MicroRNA-630 Suppresses Epithelial-to-Mesenchymal Transition by Regulating FoxM1 in Gastric Cancer Cells. target gene hsa-mir-200c "Carcinoma, Hepatocellular" 28609841 MiR-200c-5p suppresses proliferation and metastasis of human hepatocellular carcinoma (HCC) via suppressing MAD2L1. target gene hsa-mir-137 "Carcinoma, Lung, Non-Small-Cell" 28610956 Upregulation of microRNA-137 expression by Slug promotes tumor invasion and metastasis of non-small cell lung cancer cells through suppression of TFAP2C. target gene hsa-mir-222 "Adenocarcinoma, Lung" 28617551 "MiR-222 promotes proliferation, migration and invasion of lung adenocarcinoma cells by targeting ETS1." target gene hsa-mir-1 "Carcinoma, Bladder" 28618950 MiR-1-3p inhibits the proliferation and invasion of bladder cancer cells by suppressing CCL2 expression. target gene hsa-mir-105 Glioma 28618952 MicroRNA-105 inhibits human glioma cell malignancy by directly targeting SUZ12. target gene hsa-mir-208b Osteosarcoma 28618961 MicroRNA-208b inhibits human osteosarcoma progression by targeting ROR2. target gene hsa-mir-221 "Carcinoma, Gastric" 28618968 miR-221 and miR-222 synergistically regulate hepatocyte growth factor activator inhibitor type 1 to promote cell proliferation and migration in gastric cancer. target gene hsa-mir-222 "Carcinoma, Gastric" 28618968 miR-221 and miR-222 synergistically regulate hepatocyte growth factor activator inhibitor type 1 to promote cell proliferation and migration in gastric cancer. target gene hsa-mir-31 "Carcinoma, Hepatocellular" 28623129 "Increased expression of microRNA-31-5p inhibits cell proliferation, migration, and invasion via regulating Sp1 transcription factor in HepG2 hepatocellular carcinoma cell line." target gene hsa-mir-375 "Squamous Cell Carcinoma, Oral" 28627030 MiR-375/SLC7A11 axis regulates oral squamous cell carcinoma proliferation and invasion. target gene hsa-mir-495 Preeclampsia 28628915 MiR-495 Promotes Senescence of Mesenchymal Stem Cells by Targeting Bmi-1. target gene hsa-mir-330 "Carcinoma, Lung, Non-Small-Cell" 28629431 MicroRNA-330-3p promotes cell invasion and metastasis in non-small cell lung cancer through GRIA3 by activating MAPK/ERK signaling pathway. target gene hsa-mir-500 "Carcinoma, Prostate" 28631332 Inhibition of microRNA-500 has anti-cancer effect through its conditional downstream target of TFPI in human prostate cancer. target gene hsa-mir-1285 "Carcinoma, Lung, Non-Small-Cell" 28631567 MicroRNA-1285-5p influences the proliferation and metastasis of non-small-cell lung carcinoma cells via downregulating CDH1 and Smad4. target gene hsa-mir-1236 "Carcinoma, Lung" 28631573 Effects of miR-1236-3p and miR-370-5p on activation of p21 in various tumors and its inhibition on the growth of lung cancer cells. target gene hsa-mir-370 "Carcinoma, Lung" 28631573 Effects of miR-1236-3p and miR-370-5p on activation of p21 in various tumors and its inhibition on the growth of lung cancer cells. target gene hsa-mir-125a "Carcinoma, Lung" 28631574 MicroRNA-125a-5p plays a role as a tumor suppressor in lung carcinoma cells by directly targeting STAT3. target gene hsa-mir-646 "Carcinoma, Gastric" 28632723 MiR-646 inhibited cell proliferation and EMT-induced metastasis by targeting FOXK1 in gastric cancer. target gene hsa-mir-146a Osteoarthritis 28634214 Effects of microRNA-146a on the proliferation and apoptosis of human osteochondrocytes by targeting TRAF6 through the NF- ¦ÊB signalling pathway. target gene hsa-mir-148a Glomerulonephritis 28637300 "The type of diet intake also influenced cytokine production, fecal microbiota (increased Lachnospiraceae in mice fed on 2018), altered microRNAs (miRNAs; higher levels of lupus-associated miR-148a and miR-183 in mice fed on 7013 and/or 2018) and altered DNA methylation." target gene hsa-mir-183 Glomerulonephritis 28637300 "The type of diet intake also influenced cytokine production, fecal microbiota (increased Lachnospiraceae in mice fed on 2018), altered microRNAs (miRNAs; higher levels of lupus-associated miR-148a and miR-183 in mice fed on 7013 and/or 2018) and altered DNA methylation." target gene hsa-mir-26a "Carcinoma, Breast" 28637868 Post-transcriptional regulation of ERBB2 by miR26a/b and HuR confers resistance to tamoxifen in estrogen receptor-positive breast cancer cells. target gene hsa-mir-26b "Carcinoma, Breast" 28637868 Post-transcriptional regulation of ERBB2 by miR26a/b and HuR confers resistance to tamoxifen in estrogen receptor-positive breast cancer cells. target gene hsa-mir-195 "Carcinoma, Pancreatic" 28639885 MicroRNA-195 inhibits the proliferation and invasion of pancreatic cancer cells by targeting the fatty acid synthase/Wnt signaling pathway. target gene hsa-mir-138 "Carcinoma, Hepatocellular" 28639887 MicroRNA-138 enhances TRAIL-induced apoptosis through interferon-stimulated gene 15 downregulation in hepatocellular carcinoma cells. target gene hsa-mir-557 "Carcinoma, Lung" 28639890 MiR-557 works as a tumor suppressor in human lung cancers by negatively regulating LEF1 expression. target gene hsa-mir-193a "Carcinoma, Renal Cell" 28639901 Downregulation of miR-193a-3p inhibits cell growth and migration in renal cell carcinoma by targeting PTEN. target gene hsa-mir-26a "Lymphoma, Large B-Cell, Diffuse" 28640256 "MicroRNA-26a/cyclin-dependent kinase 5 axis controls proliferation, apoptosis and in vivo tumor growth of diffuse large B-cell lymphoma cell lines." target gene hsa-mir-26a Colorectal Carcinoma 28640257 Tumor-suppressive miR-26a and miR-26b inhibit cell aggressiveness by regulating FUT4 in colorectal cancer. target gene hsa-mir-26b Colorectal Carcinoma 28640257 Tumor-suppressive miR-26a and miR-26b inhibit cell aggressiveness by regulating FUT4 in colorectal cancer. target gene hsa-mir-337 "Carcinoma, Cervical" 28641487 MicroRNA-337 inhibits cell proliferation and invasion of cervical cancer through directly targeting specificity protein 1. target gene hsa-mir-133b "Carcinoma, Lung" 28641694 MiR-133b Affect the Proliferation and Drug Sensitivity in A549 Lung Cancer Stem Cells by Targeting PKM2. target gene hsa-mir-217 Cardiac Myxoma 28642131 miR-217 suppresses proliferation and promotes apoptosis in cardiac myxoma by targeting Interleukin-6. target gene hsa-mir-205 "Carcinoma, Cervical" 28651495 MiR-205 serves as a prognostic factor and suppresses proliferation and invasion by targeting insulin-like growth factor receptor 1 in human cervical cancer. target gene hsa-mir-144 "Carcinoma, Pancreatic" 28653602 "miR-144-3p Targets FosB Proto-oncogene, AP-1 Transcription Factor Subunit (FOSB) to Suppress Proliferation, Migration, and Invasion of PANC-1 Pancreatic Cancer Cells." target gene hsa-mir-181a "Carcinoma, Cervical" 28653606 miR-181a-5p Promotes Proliferation and Invasion and Inhibits Apoptosis of Cervical Cancer Cells via Regulating Inositol Polyphosphate-5-Phosphatase A (INPP5A). target gene hsa-mir-129 "Carcinoma, Gastric" 28653880 MiR-129-5p influences the progression of gastric cancer cells through interacting with SPOCK1. target gene hsa-mir-150 "Carcinoma, Thyroid, Papillary" 28656254 "MicroRNA-150 targets Rho-associated protein kinase 1 to inhibit cell proliferation, migration and invasion in papillary thyroid carcinoma." target gene hsa-mir-148b Melanoma 28656878 Proteasome beta-4 subunit contributes to the development of melanoma and is regulated by miR-148b. target gene hsa-mir-136 "Carcinoma, Gastric" 28656883 MiR-136 inhibits gastric cancer-specific peritoneal metastasis by targeting HOXC10. target gene hsa-mir-210 Ischemic Diseases [unspecific] 28661226 MicroRNA-210 alleviates oxidative stress-associated cardiomyocyte apoptosis by regulating BNIP3. target gene hsa-mir-146a Sepsis 28662100 "miR-146a, miR-146b, and miR-155 increase expression of IL-6 and IL-8 and support HSP10 in an In vitro sepsis model." target gene hsa-mir-146b Sepsis 28662100 "miR-146a, miR-146b, and miR-155 increase expression of IL-6 and IL-8 and support HSP10 in an In vitro sepsis model." target gene hsa-mir-155 Sepsis 28662100 "miR-146a, miR-146b, and miR-155 increase expression of IL-6 and IL-8 and support HSP10 in an In vitro sepsis model." target gene hsa-mir-34a "Carcinoma, Hepatocellular" 28667294 0404 inhibits hepatocellular carcinoma through a p53/miR-34a/SIRT1 positive feedback loop. target gene hsa-mir-34a "Carcinoma, Hepatocellular" 28667334 3'UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinoma. target gene hsa-mir-16 Gastric Neoplasms 28667493 MiR-16-1 Targeted Silences Far Upstream Element Binding Protein 1 to Advance the Chemosensitivity to Adriamycin in Gastric Cancer. target gene hsa-mir-155 "Carcinoma, Salivary Adenoid Cystic" 28668836 MicroRNA Profiling and Target Genes Related to Metastasis of Salivary Adenoid Cystic Carcinoma. target gene hsa-mir-205 "Carcinoma, Salivary Adenoid Cystic" 28668836 MicroRNA Profiling and Target Genes Related to Metastasis of Salivary Adenoid Cystic Carcinoma. target gene hsa-mir-664a Osteosarcoma 28669734 Inhibition of miR-664a interferes with the migration of osteosarcoma cells via modulation of MEG3. target gene hsa-let-7b "Carcinoma, Hepatocellular" 28671046 Let7b modulates the Wnt/¦Â-catenin pathway in liver cancer cells via downregulated Frizzled4. target gene hsa-mir-204 "Carcinoma, Breast" 28675122 MiR-204/ZEB2 axis functions as key mediator for MALAT1-induced epithelial-mesenchymal transition in breast cancer. target gene hsa-mir-372 Pancreatic Adenocarcinoma 28677209 Downregulation of ULK1 by microRNA-372 inhibits the survival of human pancreatic adenocarcinoma cells. target gene hsa-mir-138 "Carcinoma, Hepatocellular" 28677784 MicroRNA-138 inhibits cell proliferation in hepatocellular carcinoma by targeting Sirt1. target gene hsa-mir-30a Lung Neoplasms 28678320 MiR-30 suppresses lung cancer cell 95D epithelial mesenchymal transition and invasion through targeted regulating Snail. target gene hsa-mir-107 Osteosarcoma 28682874 In vitro effect of microRNA-107 targeting Dkk-1 by regulation of Wnt/¦Â-catenin signaling pathway in osteosarcoma target gene hsa-mir-150 Neuropathic Pain 28685867 MiR-150 alleviates neuropathic pain via inhibiting toll-like receptor 5. target gene hsa-mir-34a Atherosclerosis 28688900 MiR-34a/sirtuin-1/foxo3a is involved in genistein protecting against ox-LDL-induced oxidative damage in HUVECs. target gene hsa-mir-155 Lung Neoplasms 28688901 MicroRNA-155 regulates arsenite-induced malignant transformation by targeting Nrf2-mediated oxidative damage in human bronchial epithelial cells. target gene hsa-mir-200b "Carcinoma, Hepatocellular" 28695771 MicroRNA-200b suppresses the invasion and migration of hepatocellular carcinoma by downregulating RhoA and circRNA_000839. target gene hsa-mir-125b "Carcinoma, Nasopharyngeal" 28698199 MiR-125b Increases Nasopharyngeal Carcinoma Radioresistance by Targeting A20/NF-¦ÊB Signaling Pathway. target gene hsa-let-7a Melanoma 28698805 MicroRNA-26a inhibits the growth and invasiveness of malignant melanoma and directly targets on MITF gene. target gene hsa-mir-26a Melanoma 28698805 MicroRNA-26a inhibits the growth and invasiveness of malignant melanoma and directly targets on MITF gene. target gene hsa-mir-613 Gastric Neoplasms 28701053 MicroRNA-613 inhibits the progression of gastric cancer by targeting CDK9. target gene hsa-mir-25 Osteosarcoma 28705117 "MicroRNA-25 suppresses proliferation, migration, and invasion of osteosarcoma by targeting SOX4." target gene hsa-mir-145 Retinoblastoma 28706438 Genistein suppresses retinoblastoma cell viability and growth and induces apoptosis by upregulating miR-145 and inhibiting its target ABCE1. target gene hsa-mir-138 Colorectal Carcinoma 28707774 "Hsa_circ_0020397 regulates colorectal cancer cell viability, apoptosis and invasion by promoting the expression of the miR-138 targets TERT and PD-L1." target gene hsa-mir-320 Gastric Neoplasms 28713899 miR-320a serves as a negative regulator in the progression of gastric cancer by targeting RAB14. target gene hsa-mir-34a "Carcinoma, Colon" 28713966 Spica Prunellae extract suppresses the growth of human colon carcinoma cells by targeting multiple oncogenes via activating miR-34a. target gene hsa-mir-125b "Carcinoma, Lung, Non-Small-Cell" 28713974 miRNA-125b regulates apoptosis of human non-small cell lung cancer via the PI3K/Akt/GSK3¦Â signaling pathway. target gene hsa-mir-219 "Carcinoma, Lung, Non-Small-Cell" 28714014 MicroRNA-219 is downregulated in non-small cell lung cancer and inhibits cell growth and metastasis by targeting HMGA2. target gene hsa-mir-200a "Carcinoma, Renal Cell" 28717923 MiRNA-200a induce cell apoptosis in renal cell carcinoma by directly targeting SIRT1. target gene hsa-mir-143 "Carcinoma, Gastric" 28718369 MiR-143 inhibits cell proliferation and invasion by targeting DNMT3A in gastric cancer. target gene hsa-mir-592 Glioma 28718372 MiR-592 functions as a tumor suppressor in glioma by targeting IGFBP2. target gene hsa-mir-139 "Carcinoma, Bladder" 28720065 MicroRNA-139-5p inhibits bladder cancer proliferation and self-renewal by targeting the Bmi1 oncogene. target gene hsa-mir-375 Melanoma 28723760 "CXCL8 interacted with STAT1, CCL27, and IGF1R targeted by hsa-miR-375" target gene hsa-mir-378 Colon Neoplasms 28725241 "miR-378 suppresses the proliferation, migration and invasion of colon cancer cells by inhibiting SDAD1." target gene hsa-mir-200c Lung Neoplasms 28727734 "MicroRNA-200c inhibits epithelial-mesenchymal transition, invasion, and migration of lung cancer by targeting HMGB1." target gene hsa-let-7c Breast Neoplasms 28731186 Let-7c-5p inhibits cell proliferation and induces cell apoptosis by targeting ERCC6 in breast cancer target gene hsa-mir-181a "Leukemia, Lymphoblastic, Acute" 28732737 MicroRNA-181a and its target Smad 7 as potential biomarkers for tracking child acute lymphoblastic leukemia target gene hsa-mir-143 Osteosarcoma 28734729 MiR-143 regulates the proliferation and migration of osteosarcoma cells through targeting MAPK7. target gene hsa-mir-27b "Squamous Cell Carcinoma, Oral" 28735227 MicroRNA-27b inhibits cell proliferation in oral squamous cell carcinoma by targeting FZD7 and Wnt signaling pathway. target gene hsa-mir-143 Lymphoma 28736328 Down regulation of miR-143 promotes radiation - Induced thymic lymphoma by targeting B7H1. target gene hsa-mir-21 Ischemia-Reperfusion Injury 28737660 Renal Protection Mediated by Hypoxia Inducible Factor-1¦Á Depends on Proangiogenesis Function of miR-21 by Targeting Thrombospondin 1. target gene hsa-mir-21 Pituitary Neoplasms 28742208 Effects of microRNA-21 targeting PITX2 on proliferation and apoptosis of pituitary tumor cells. target gene hsa-mir-133a Colorectal Carcinoma 28748780 miR-133a-3p Targets SUMO-Specific Protease 1 to Inhibit Cell Proliferation and Cell Cycle Progress in Colorectal Cancer. target gene hsa-mir-429 Glioblastoma 28749077 MiR-429 suppresses glioblastoma multiforme by targeting SOX2. target gene hsa-mir-1254 "Carcinoma, Lung, Non-Small-Cell" 28749936 MiR-1254 suppresses HO-1 expression through seed region-dependent silencing and non-seed interaction with TFAP2A transcript to attenuate NSCLC growth. target gene hsa-mir-195 Lung Neoplasms 28752530 "HMGA2 regulation by microRNA-195 (miR-195) was validated by real time-PCR, Western blotting, and luciferase reporter assays" target gene hsa-mir-155 Marek Disease 28757026 Marek's disease virus type 1 encoded analog of miR-155 promotes proliferation of chicken embryo fibroblast and DF-1 cells by targeting hnRNPAB. target gene hsa-mir-137 Melanoma 28757416 "The tumour suppressor, miR-137, inhibits malignant melanoma migration by targetting the TBX3 transcription factor." target gene hsa-mir-21 Cardio-Renal Syndrome 28760335 "MicroRNA-21 regulates peroxisome proliferator-activated receptor alpha, a molecular mechanism of cardiac pathology in Cardiorenal Syndrome Type 4." target gene hsa-mir-143 "Carcinoma, Hepatocellular" 28765889 Downregulation of microRNA-143 promotes cell proliferation by regulating PKC¦Å in hepatocellular carcinoma cells. target gene hsa-mir-206 Encephalitis 28765968 Downregulation of CCL2 induced by the upregulation of microRNA-206 is associated with the severity of HEV71 encephalitis target gene hsa-mir-182 Colorectal Carcinoma 28767179 Upregulation of microRNA-135b and microRNA-182 promotes chemoresistance of colorectal cancer by targeting ST6GALNAC2 via PI3K/AKT pathway. target gene hsa-mir-132 Melanoma 28767374 "hsa-mir-132,downregulates expression levels of p120RasGAP" target gene hsa-mir-144 Preeclampsia 28772212 "miR-144 may regulate the proliferation, migration and invasion of trophoblastic cells through targeting PTEN in preeclampsia." target gene hsa-mir-524 Glioma 28778566 EGFR/c-myc axis regulates TGF¦Â/Hippo/Notch pathway via epigenetic silencing miR-524 in gliomas. target gene hsa-mir-203 "Carcinoma, Hepatocellular" 28781949 miR-203a-3p.1 targets IL-24 to modulate hepatocellular carcinoma cell growth and metastasis. target gene hsa-mir-18a Muscle Atrophy 28782600 miR-18a induces myotubes atrophy by down-regulating IgfI. target gene hsa-mir-124 Glioma 28791348 MicroRNA-124 inhibits the proliferation of C6 glioma cells by targeting Smad4. target gene hsa-mir-195 "Carcinoma, Laryngeal" 28791411 MicroRNA-195 inhibits growth and invasion of laryngeal carcinoma cells by directly targeting DCUN1D1. target gene hsa-mir-133a Vascular Hypertrophy 28795305 microRNA-133a attenuates cardiomyocyte hypertrophy by targeting PKC¦Ä and Gq. target gene hsa-mir-3144 Arrhythmia 28796037 miR-3144-5p overexpression plays a role in HCMs by regulating these genes and TF target gene hsa-mir-4262 "Carcinoma, Cervical" 28800784 Upregulation of MicroRNA-4262 Targets Kaiso (ZBTB33) to Inhibit the Proliferation and EMT of Cervical Cancer Cells. target gene hsa-mir-449a "Carcinoma, Lung, Non-Small-Cell" 28800787 MiR-449a Suppresses LDHA-Mediated Glycolysis to Enhance the Sensitivity of Non-Small Cell Lung Cancer Cells to Ionizing Radiation. target gene hsa-mir-204 Cervical Neoplasms 28800788 MiR-204 Regulates Cell Proliferation and Invasion by Targeting EphB2 in Human Cervical Cancer target gene hsa-mir-641 Lung Neoplasms 28800790 miR-641 Functions as a Tumor Suppressor by Targeting MDM2 in Human Lung Cancer. target gene hsa-mir-154 Gastric Neoplasms 28800791 MicroRNA-154 Inhibits the Growth and Invasion of Gastric Cancer Cells by Targeting DIXDC1/WNT Signaling. target gene hsa-mir-145 Colorectal Carcinoma 28802228 MTDH and MAP3K1 are direct targets of apoptosis-regulating miRNAs in colorectal carcinoma target gene hsa-mir-375 Colorectal Carcinoma 28802228 MTDH and MAP3K1 are direct targets of apoptosis-regulating miRNAs in colorectal carcinoma target gene hsa-mir-181c Lung Neoplasms 28806967 MicroRNA-181c inhibits cigarette smoke-induced chronic obstructive pulmonary disease by regulating CCN1 expression. target gene hsa-mir-21 Kidney Diseases [unspecific] 28808068 Overexpression of renal Smad7 protects against hypertensive nephropathy by inactivating angiotensin II-induced TGF-¦Â/Smad3 and NF-¦ÊB pathways and by targeting the Smad3-dependent microRNA-21 axis target gene hsa-mir-375 "Squamous Cell Carcinoma, Oral" 28810236 MicroRNA-375 Inhibits Growth and Enhances Radiosensitivity in Oral Squamous Cell Carcinoma by Targeting Insulin Like Growth Factor 1 Receptor. target gene hsa-mir-9 Melanoma 28810544 MicroRNA-9 inhibits the proliferation and migration of malignant melanoma cells via targeting sirituin 1. target gene hsa-mir-152 Osteosarcoma 28810933 MicroRNA-152 Suppresses Human Osteosarcoma Cell Proliferation and Invasion by Targeting E2F Transcription Factor 3. target gene hsa-mir-21 Myocardial Infarction 28817807 Mir-21 Promotes Cardiac Fibrosis After Myocardial Infarction Via Targeting Smad7. target gene hsa-mir-200a Neoplasms [unspecific] 28817830 MicroRNA-200a Inhibits Transforming Growth Factor ¦Â1-Induced Proximal Tubular Epithelial-Mesenchymal Transition by Targeting ¦Â-Catenin. target gene hsa-mir-21 Atherosclerosis 28823833 MicroRNA-21 suppresses ox-LDL-induced human aortic endothelial cells injuries in atherosclerosis through enhancement of autophagic flux: Involvement in promotion of lysosomal function. target gene hsa-mir-124 Gastric Neoplasms 28829503 MicroRNA-124 inhibits cell invasion and epithelial-mesenchymal transition by directly repressing Snail2 in gastric cancer target gene hsa-mir-200c Breast Neoplasms 28829888 MiR-200c inhibits metastasis of breast tumor via the downregulation of Foxf2. target gene hsa-mir-367 Melanoma 28829890 miR-367 promotes uveal melanoma cell proliferation and migration by regulating PTEN. target gene hsa-mir-130a Gastric Neoplasms 28831264 microRNA-130a is an oncomir suppressing the expression of CRMP4 in gastric cancer target gene hsa-mir-31 "Adenocarcinoma, Gastric" 28836853 MicroRNA-31 inhibits RhoA-mediated tumor invasion and chemotherapy resistance in MKN-45 gastric adenocarcinoma cells. target gene hsa-mir-204 Hypertension 28839162 MicroRNA-204 promotes vascular endoplasmic reticulum stress and endothelial dysfunction by targeting Sirtuin1. target gene hsa-mir-494 Ischemia-Reperfusion Injury 28842516 miR-494 up-regulates the PI3K/Akt pathway via targetting PTEN and attenuates hepatic ischemia/reperfusion injury in a rat model. target gene hsa-mir-22 Arteriosclerosis Obliterans 28848136 Our results indicate that miR-22-3p is a key molecule in regulating HASMC proliferation and migration by targeting HMGB1 and that miR-22-3p and HMGB1 may be therapeutic targets in the treatment of human ASO. target gene hsa-mir-15a "Carcinoma, Renal Cell" 28849086 Downregulation of microRNA-15a suppresses the proliferation and invasion of renal cell carcinoma via direct targeting of eIF4E. target gene hsa-mir-130a Colorectal Carcinoma 28849155 MicroRNA-130a is upregulated in colorectal cancer and promotes cell growth and motility by directly targeting forkhead box F2. target gene hsa-mir-182 Atherosclerosis 28855441 MicroRNA-182 Promotes Lipoprotein Lipase Expression and Atherogenesisby Targeting Histone Deacetylase 9 in Apolipoprotein E-Knockout Mice. target gene hsa-mir-222 Colorectal Carcinoma 28855850 MicroRNA-222 influences migration and invasion through MIA3 in colorectal cancer target gene hsa-mir-34a Glioma 28859546 MicroRNA-34a induces transdifferentiation of glioma stem cells into vascular endothelial cells by targeting Notch pathway. target gene hsa-mir-204 Prostate Neoplasms 28861151 microRNA-204 modulates chemosensitivity and apoptosis of prostate cancer cells by targeting zinc-finger E-box-binding homeobox 1 (ZEB1). target gene hsa-mir-138 "Carcinoma, Renal Cell, Clear-Cell" 28861152 MicroRNA-138 attenuates epithelial-to-mesenchymal transition by targeting SOX4 in clear cell renal cell carcinoma. target gene hsa-mir-127 Bone Cancer 28866093 MiR-127 and miR-376a act as tumor suppressors by in?vivo targeting of COA1 and PDIA6 in giant cell tumor of bone. target gene hsa-mir-376a Bone Cancer 28866093 MiR-127 and miR-376a act as tumor suppressors by in?vivo targeting of COA1 and PDIA6 in giant cell tumor of bone. target gene hsa-mir-107 "Carcinoma, Hepatocellular" 28867541 miR-107-mediated decrease of HMGCS2 indicates poor outcomes and promotes cell migration in hepatocellular carcinoma target gene hsa-mir-15a Arthritis 28877850 Gabapentin regulates expression of FGF2 and FGFR1 in dorsal root ganglia via microRNA-15a in the arthritis rat model. target gene hsa-mir-4317 Gastric Neoplasms 28880489 miRNA-4317 suppresses human gastric cancer cell proliferation by targeting ZNF322. target gene hsa-mir-126 "Carcinoma, Hepatocellular" 28881749 "Effects of microRNA-126 on cell proliferation, apoptosis and tumor angiogenesis via the down-regulating ERK signaling pathway by targeting EGFL7 in hepatocellular carcinoma" target gene hsa-mir-106b Cholangiocarcinoma 28881782 miR-106b regulates the 5-fluorouracil resistance by targeting Zbtb7a in cholangiocarcinoma target gene hsa-mir-106a Prostate Neoplasms 28889725 Oncogene miR-106a promotes proliferation and metastasis of prostate cancer cells by directly targeting PTEN in vivo and in vitro. target gene hsa-mir-150 Lung Neoplasms 28891208 Serum MicroRNA-150 Predicts Prognosis for Early-Stage Non-Small Cell Lung Cancer and Promotes Tumor Cell Proliferation by Targeting Tumor Suppressor Gene SRCIN1. target gene hsa-mir-96 hepatocellular carcinoma 28892647 "miR-96 targets SOX6 and promotes proliferation, migration, and invasion of hepatocellular carcinoma" target gene hsa-mir-34a "Fatty Liver, Non-Alcoholic" 28899784 MiR-181b regulates steatosis in nonalcoholic fatty liver disease via targeting SIRT1. target gene hsa-mir-149 "Carcinoma, Renal Cell" 28902136 Dual Strands of Pre-miR-149 Inhibit Cancer Cell Migration and Invasion through Targeting FOXM1 in Renal Cell Carcinoma. target gene hsa-mir-217 Colorectal Carcinoma 28905214 "miR-217-5p induces apoptosis by directly targeting PRKCI, BAG3, ITGAV and MAPK1 in colorectal cancer cells." target gene hsa-mir-16 Cholangiocarcinoma 28915618 Suppression of miR-16 promotes tumor growth and metastasis through reversely regulating YAP1 in human cholangiocarcinoma. target gene hsa-mir-25 Neoplasms [unspecific] 28920955 miR-25/93 mediates hypoxia-induced immunosuppression by repressing cGAS. target gene hsa-mir-21 Rectal Neoplasms 28927090 Downregulation of PDCD4 by miR-21 suppresses tumor transformation and proliferation in a nude mouse renal cancer model. target gene hsa-mir-181a "Carcinoma, Hepatocellular" 28930552 MicroRNA-181a inhibits autophagy by targeting Atg5 in hepatocellular carcinoma target gene hsa-mir-181a "Squamous Cell Carcinoma, Skin or Unspecific" 28931048 miR-181a decelerates proliferation in cutaneous squamous cell carcinoma by targeting the proto-oncogene KRAS. target gene hsa-mir-200c Breast Neoplasms 28933253 The role of p53-microRNA 200-Moesin axis in invasion and drug resistance of breast cancer cells. target gene hsa-mir-320 Glioma 28934982 MiR-320 inhibits the growth of glioma cells through downregulating PBX3. target gene hsa-mir-21 Breast Neoplasms 28935174 TIMP-3 mRNA expression levels positively correlates with levels of miR-21 in in situ BC and negatively in PR positive invasive BC. target gene hsa-mir-130a Neoplasms [unspecific] 28935812 miR-130a Deregulates PTEN and Stimulates Tumor Growth. target gene hsa-mir-124 Gastric Neoplasms 28941308 In vivo and in vitro effects of microRNA-124 on human gastric cancer by targeting JAG1 through the Notch signaling pathway. target gene hsa-mir-126 Diabetic Retinopathy 28943945 MicroRNA-126 inhibits cell viability and invasion in a diabetic retinopathy model via targeting IRS-1. target gene hsa-mir-26b Breast Neoplasms 28944451 Expression of miRNA-26b-5p and its target TRPS1 is associated with radiation exposure in post-Chernobyl breast cancer. target gene hsa-mir-181a "Carcinoma, Lung, Non-Small-Cell" 28946554 MiR-181a inhibits non-small cell lung cancer cell proliferation by targeting CDK1. target gene hsa-mir-21 Leukemia 28947822 "Microenvironment regulates the expression of miR-21 and tumor suppressor genes PTEN, PIAS3 and PDCD4 through ZAP-70 in chronic lymphocytic leukemia." target gene hsa-mir-125a Osteosarcoma 28950256 MicroRNA-125a Regulates Cell Proliferation Via Directly Targeting E2F2 in Osteosarcoma target gene hsa-mir-500a Neoplasms [unspecific] 28952053 Cancer-associated genes LIF and PAPPA are possible targets of miR-500a-3p target gene hsa-mir-214 "Squamous Cell Carcinoma, Esophageal" 28954387 MiR-214 inhibits the proliferation and invasion of esophageal squamous cell carcinoma cells by targeting CDC25B. target gene hsa-mir-18a Alzheimer Disease 28956815 "hsa-mir-18a, having common key targets in the BARHL1-ESR1 network and AD pathway" target gene hsa-mir-21 Colorectal Carcinoma 28957811 MicroRNA-21 (Mir-21) Promotes Cell Growth and Invasion by Repressing Tumor Suppressor PTEN in Colorectal Cancer. target gene hsa-mir-138 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 28962111 MicroRNA-138 suppresses cell proliferation in laryngeal squamous cell carcinoma via inhibiting EZH2 and PI3K/AKT signaling. target gene hsa-mir-191 "Diabetes Mellitus, Type 2" 28963693 "MicroRNA-191, acting via the IRS-1/Akt signaling pathway, is involved in the hepatic insulin resistance induced by cigarette smoke extract." target gene hsa-mir-124 Pulmonary Hypertension 28972001 Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis. target gene hsa-mir-629 Ovarian Neoplasms 28972400 Knockdown of miR-629 Inhibits Ovarian Cancer Malignant Behaviors by Targeting Testis-Specific Y-Like Protein 5. target gene hsa-mir-200b "Carcinoma, Breast" 28972876 miR-200b regulates epithelial-mesenchymal transition of chemo-resistant breast cancer cells by targeting FN1. target gene hsa-mir-26a "Carcinoma, Skin" 28977801 MiR-26a Mediates Ultraviolet B-Induced Apoptosis by Targeting Histone Methyltransferase EZH2 Depending on Myc Expression. target gene hsa-mir-23b Gastric Neoplasms 28981115 miR-23a/b promote tumor growth and suppress apoptosis by targeting PDCD4 in gastric cancer. target gene hsa-mir-1 Rhabdomyosarcoma 28981396 miR-133b also knock downed PAX3-FOXO1 target gene hsa-mir-17 "Adenocarcinoma, Pancreatic Ductal" 28987387 MiR-17-5p enhances pancreatic cancer proliferation by altering cell cycle profiles via disruption of RBL2/E2F4-repressing complexes. target gene hsa-mir-29a Rheumatoid Arthritis 28987940 MicroRNA-29a inhibits proliferation and induces apoptosis in rheumatoid arthritis fibroblast-like synoviocytes by repressing STAT3. target gene hsa-mir-205 Gastric Neoplasms 28987942 miR-205 regulation of ICT1 has an oncogenic potential via promoting the migration and invasion of gastric cancer cells. target gene hsa-mir-206 "Squamous Cell Carcinoma, Head and Neck" 28987947 MiR-206 inhibits Head and neck squamous cell carcinoma cell progression by targeting HDAC6 via PTEN/AKT/mTOR pathway. target gene hsa-mir-205 Colorectal Carcinoma 28990808 MicroRNA-205 Mediates Proteinase-Activated Receptor 2 (PAR2) -Promoted Cancer Cell Migration. target gene hsa-mir-16 Melanoma 28991221 TYRP1-dependent miR-16 sequestration can also be overcome in vivo by using small oligonucleotides that mask miR-16-binding sites on TYRP1 mRNA target gene hsa-mir-7 Brain Neoplasms 29016934 microRNA-7 upregulates death receptor 5 and primes resistant brain tumors to caspase-mediated apoptosis. target gene hsa-mir-210 Pheochromocytoma 29018330 MicroRNA-210 Protects PC-12 Cells Against Hypoxia-Induced Injury by Targeting BNIP3. target gene hsa-mir-34a Liver Diseases [unspecific] 29018509 These findings indicate a circRNA_0046367/miR-34a/PPAR¦Á regulatory system underlying hepatic steatosis target gene hsa-mir-34a Preeclampsia 29022890 Elevated microRNA-34a contributes to trophoblast cell apoptosis in preeclampsia by targeting BCL-2. target gene hsa-mir-150 Thyroid Neoplasms 29023429 MiR-150 Inhibits Cell Growth In Vitro and In Vivo by Restraining the RAB11A/WNT/¦Â-Catenin Pathway in Thyroid Cancer. target gene hsa-mir-29a Neurilemmoma 29023945 MicroRNA-29a inhibits proliferation and motility of schwannoma cells by targeting CDK6. target gene hsa-mir-29c Neurilemmoma 29023945 MicroRNA-29a inhibits proliferation and motility of schwannoma cells by targeting CDK6. target gene hsa-mir-1 Diabetic Cardiomyopathies 29024600 Liver X receptor ¦Á is targeted by microRNA-1 to inhibit cardiomyocyte apoptosis through a ROS-mediated mitochondrial pathway. target gene hsa-mir-373 "Carcinoma, Lung, Non-Small-Cell" 29025258 MicroRNA-373 Inhibits Cell Proliferation and Invasion via Targeting BRF2 in Human Non-small Cell Lung Cancer A549 Cell Line. target gene hsa-mir-124 "Carcinoma, Lung, Non-Small-Cell" 29039564 Evaluation of microRNA-203 in bone metastasis of patients with non-small cell lung cancer through TGF-¦Â/SMAD2 expression. target gene hsa-mir-124 Melanoma 29042947 "miR-124 inhibits proliferation, migration and invasion of malignant melanoma cells via targeting versican." target gene hsa-mir-138 Osteosarcoma 29042962 MicroRNA-138 directly targets TNFAIP8 and acts as a tumor suppressor in osteosarcoma. target gene hsa-mir-17 Endometriosis 29042983 MicroRNA-17 downregulates expression of the PTEN gene to promote the occurrence and development of adenomyosis. target gene hsa-mir-29b Ovarian Neoplasms 29050034 Mir-29b Regulates Oxidative Stress by Targeting SIRT1 in Ovarian Cancer Cells. target gene hsa-let-7a "Carcinoma, Thyroid, Papillary" 29050238 "Let-7a inhibits migration, invasion and tumor growth by targeting AKT2 in papillary thyroid carcinoma." target gene hsa-mir-574 Spinal Chordoma 29051990 Clinicopathologic implications of CD8+/Foxp3+ ratio and miR-574-3p/PD-L1 axis in spinal chordoma patients. target gene hsa-mir-767 Melanoma 29054757 MiR-767 promoted cell proliferation in human melanoma by suppressing CYLD expression. target gene hsa-mir-145 Stroke 29057271 Overexpression of MicroRNA-145 Ameliorates Astrocyte Injury by Targeting Aquaporin 4 in Cerebral Ischemic Stroke target gene hsa-mir-302a Periodontitis 29058810 miR-302a-3p regulates RANKL expression in human mandibular osteoblast-like cells. target gene hsa-mir-181a "Carcinoma, Renal Cell, Clear-Cell" 29066014 "Up-regulation of miR-181a in clear cell renal cell carcinoma is associated with lower KLF6 expression, enhanced cell proliferation, accelerated cell cycle transition, and diminished apoptosis." target gene hsa-mir-155 Neoplasms [unspecific] 29066622 MicroRNA-155 induction via TNF-¦Á and IFN-¦Ã suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells. target gene hsa-mir-148a "Squamous Cell Carcinoma, Esophageal" 29067119 MiR-148a modulates HLA-G expression and influences tumor apoptosis in esophageal squamous cell carcinoma. target gene hsa-mir-21 "Lymphoma, Large B-Cell, Diffuse" 29067124 MicroRNA-21 regulates the viability and apoptosis of diffuse large B-cell lymphoma cells by upregulating B cell lymphoma-2. target gene hsa-mir-140 Cartilage Disease [unspecific] 29067438 miRNA-140 inhibits C3H10T1/2 mesenchymal stem cell proliferation by targeting CXCL12 during transforming growth factor-¦Â3-induced chondrogenic differentiation. target gene hsa-mir-489 Colorectal Carcinoma 29071516 MiR-489 suppresses tumor growth and invasion by targeting HDAC7 in colorectal cancer. target gene hsa-mir-106a Kidney Osteogenic Sarcoma 29072688 MiR-106a-5p inhibits the cell migration and invasion of renal cell carcinoma through targeting PAK5. target gene hsa-mir-1 Hypertrophy 29073097 Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy. target gene hsa-mir-30a "Carcinoma, Renal Cell" 29073630 MicroRNA-30a-5p Inhibits the Growth of Renal Cell Carcinoma by Modulating GRP78 Expression. target gene hsa-mir-107 Cervical Neoplasms 29073938 "Musashi-2, a novel oncoprotein promoting cervical cancer cell growth and invasion, is negatively regulated by p53-induced miR-143 and miR-107 activation." target gene hsa-mir-143 Cervical Neoplasms 29073938 "Musashi-2, a novel oncoprotein promoting cervical cancer cell growth and invasion, is negatively regulated by p53-induced miR-143 and miR-107 activation." target gene hsa-mir-146a Inflammation 29074132 "MicroRNA-146a promotes red spotted grouper nervous necrosis virus (RGNNV) replication by targeting TRAF6 in orange spotted grouper, Epinephelus coioides." target gene hsa-mir-204 Melanoma 29075789 BANCR contributes to the growth and invasion of melanoma by functioning as a competing endogenous RNA to upregulate Notch2 expression by sponging miR?204. target gene hsa-mir-223 "Carcinoma, Ovarian, Serous" 29079174 miR-223 potentially targets SWI/SNF complex protein SMARCD1 in atypical proliferative serous tumor and high-grade ovarian serous carcinoma. target gene hsa-mir-200c "Carcinoma, Endometrial" 29080395 MicroRNA-200c Inhibits Epithelial-Mesenchymal Transition by Targeting the BMI-1 Gene Through the Phospho-AKT Pathway in Endometrial Carcinoma Cells In Vitro. target gene hsa-let-7d Parkinson Disease 29082467 Let-7d microRNA Attenuates 6-OHDA-Induced Injury by Targeting Caspase-3 in MN9D Cells. target gene hsa-mir-21 Lung Fibrosis 29084974 Mir-21 Mediates the Inhibitory Effect of Ang (1-7) on AngII-induced NLRP3 Inflammasome Activation by Targeting Spry1 in lung fibroblasts. target gene hsa-mir-106b Retinoblastoma 29085029 HBeAg-induced miR-106b promotes cell growth by targeting the retinoblastoma gene. target gene hsa-mir-21 Rectal Neoplasms 29085468 miR-21 inhibition of LATS1 promotes proliferation and metastasis of renal cancer cells and tumor stem cell phenotype. target gene hsa-mir-27a Polycystic Ovarian Syndrome 29089199 MicroRNA-27a-3p affects estradiol and androgen imbalance by targeting Creb1 in the granulosa cells in mouse polycytic ovary syndrome model. target gene hsa-mir-491 Neoplasms [unspecific] 29091292 Functional SNP in microRNA-491-5p binding site of MMP9 3'-UTR affects cancer susceptibility. target gene hsa-mir-613 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 29091303 MiR-613 suppressed the laryngeal squamous cell carcinoma progression through regulating PDK1. target gene hsa-mir-150 Cervical Neoplasms 29091902 "MicroRNA-150 promotes cell proliferation, migration, and invasion of cervical cancer through targeting PDCD4." target gene hsa-mir-34a "Squamous Cell Carcinoma, Esophageal" 29094237 MicroRNA-34a suppresses invasion and metastatic in esophageal squamous cell carcinoma by regulating CD44. target gene hsa-mir-137 Melanoma 29097210 miR-137 inhibits glutamine catabolism and growth of malignant melanoma by targeting glutaminase. target gene hsa-mir-130a Cervical Neoplasms 29099271 SOX9/miR-130a/CTR1 axis modulates DDP-resistance of cervical cancer cell. target gene hsa-mir-21 "Leukemia, Myeloid, Acute" 29100302 A tyrosine kinase-STAT5-miR21-PDCD4 regulatory axis in chronic and acute myeloid leukemia cells. target gene hsa-mir-30a Diabetic Cataract 29100392 MiR-30a inhibits BECN1-mediated autophagy in diabetic cataract. target gene hsa-mir-27a Diabetes Mellitus 29100869 Oxidative stress-induced miR-27a targets the redox gene nuclear factor erythroid 2-related factor 2 in diabetic embryopathy. target gene hsa-mir-21 Gastric Neoplasms 29101039 miR-21 modulates prostaglandin signaling and promotes gastric tumorigenesis by targeting 15-PGDH. target gene hsa-mir-27a "Fatty Liver, Non-Alcoholic" 29101357 MicroRNA-27a regulates hepatic lipid metabolism and alleviates NAFLD via repressing FAS and SCD1. target gene hsa-mir-4326 Lung Neoplasms 29101731 miR-4326 promotes lung cancer cell proliferation through targeting tumor suppressor APC2. target gene hsa-mir-146a Asthma 29101850 MicroRNA-146a promotes IgE class switch in B cells via upregulating 14-3-3¦Ò expression. target gene hsa-mir-155 Colon Neoplasms 29104623 "MicroRNA-155 regulates the proliferation, cell cycle, apoptosis and migration of colon cancer cells and targets CBL." target gene hsa-mir-150 "Fatty Liver, Non-Alcoholic" 29107687 MiR-150 deficiency ameliorated hepatosteatosis and insulin resistance in nonalcoholic fatty liver disease via targeting CASP8 and FADD-like apoptosis regulator. target gene hsa-mir-30a "Carcinoma, Hepatocellular" 29108194 MicroRNA-30a inhibits proliferation of hepatocellular carcinoma cells via targeted regulation of forkhead-box protein A1. target gene hsa-mir-10a Lupus Nephritis 29109423 Transcriptomic profiling in human mesangial cells using patient-derived lupus autoantibodies identified miR-10a as a potential regulator of IL8. target gene hsa-mir-223 Hypertrophy 29110214 SOX2-mediated inhibition of miR-223 contributes to STIM1 activation in phenylephrine-induced hypertrophic cardiomyocytes. target gene hsa-mir-107 "Adenocarcinoma, Pancreatic Ductal" 29111166 Deregulated expression of miR-107 inhibits metastasis of PDAC through inhibition PI3K/Akt signaling via caveolin-1 and PTEN. target gene hsa-mir-181b Gastric Neoplasms 29113265 The present study confirmed that CDX2 was suppressed by activation of the IL-6/STAT3 signaling pathway via miR-181b in vitro target gene hsa-mir-488 Ovarian Neoplasms 29113360 microRNA-488 inhibits chemoresistance of ovarian cancer cells by targeting Six1 and mitochondrial function. target gene hsa-mir-222 "Carcinoma, Nasopharyngeal" 29115464 microRNA-222 promotes tumor growth and confers radioresistance in nasopharyngeal carcinoma by targeting PTEN. target gene hsa-mir-200c Endometriosis 29116025 miR-200c suppresses endometriosis by targeting MALAT1 in vitro and in vivo. target gene hsa-mir-449a Osteosarcoma 29117539 Hsa_circ_0009910 promotes carcinogenesis by promoting the expression of miR-449a target IL6R in osteosarcoma. target gene hsa-mir-21 Rectal Neoplasms 29131259 MicroRNA-21 functions as an oncogene and promotes cell proliferation and invasion via TIMP3 in renal cancer. target gene hsa-mir-155 Viral Myocarditis 29136142 The forkhead transcription factor Foxo3 negatively regulates natural killer cell function and viral clearance in myocarditis. target gene hsa-mir-143 "Squamous Cell Carcinoma, Esophageal" 29137232 "Integration of metabolomics, transcriptomics, and microRNA expression profiling reveals a miR-143-HK2-glucose network underlying zinc-deficiency-associated esophageal neoplasia." target gene hsa-let-7d "Adenocarcinoma, Pancreatic Ductal" 29137251 selinexor induced the expression of two important tumor suppressive miRNAs miR-34c and let-7d leading to the up-regulation of p21WAF1 target gene hsa-mir-34c "Adenocarcinoma, Pancreatic Ductal" 29137251 selinexor induced the expression of two important tumor suppressive miRNAs miR-34c and let-7d leading to the up-regulation of p21WAF1 target gene hsa-mir-200c Gastric Neoplasms 29138864 Expression level of microRNA-200c is associated with cell morphology in vitro and histological differentiation through regulation of ZEB1/2 and E-cadherin in gastric carcinoma. target gene hsa-mir-23a "Carcinoma, Pancreatic" 29141872 miR-23a acts as an oncogene in pancreatic carcinoma by targeting FOXP2. target gene hsa-mir-24 Osteoarthritis 29143973 "Effects of microRNA-24 targeting C-myc on apoptosis, proliferation and cytokine expressions in chondrocytes of rats with osteoarthritis via MAPK signaling pathway." target gene hsa-mir-27a "Carcinoma, Hepatocellular" 29143999 MicroRNA-27a-3p inhibits cell viability and migration through down-regulating DUSP16 in hepatocellular carcinoma. target gene hsa-mir-146a Ankylosing Spondylitis 29145150 MicroRNA-146a knockdown suppresses the progression of ankylosing spondylitis by targeting dickkopf 1 target gene hsa-mir-34b Acute Lung Injury 29150939 miR-34b-5p inhibition attenuates lung inflammation and apoptosis in an LPS-induced acute lung injury mouse model by targeting progranulin. target gene hsa-mir-205 "Squamous Cell Carcinoma, Oral" 29150940 Tumor-suppressive roles of ¦¤Np63¦Â-miR-205 axis in epithelial-mesenchymal transition of oral squamous cell carcinoma via targeting ZEB1 and ZEB2 target gene hsa-mir-200c Neuropathic Pain 29150958 Inhibition of miR-200b/miR-429 contributes to neuropathic pain development through targeting zinc finger E box binding protein-1. target gene hsa-mir-429 Neuropathic Pain 29150958 Inhibition of miR-200b/miR-429 contributes to neuropathic pain development through targeting zinc finger E box binding protein-1. target gene hsa-mir-31 "Carcinoma, Hepatocellular" 29152108 MicroRNA-31 suppresses the self-renewal capability of ¦Á2¦Ä1+ liver tumor-initiating cells by targeting ISL1 target gene hsa-mir-27a Liver Injury 29156532 paclitaxel significantly attenuated septic induced liver injury through reducing inflammatory response via miR-27a/TAB3/NF-¦ÊB signaling pathway target gene hsa-mir-31 Cervical Neoplasms 29159179 miR-31 Functions as an Oncomir Which Promotes Epithelial-Mesenchymal Transition via Regulating BAP1 in Cervical Cancer target gene hsa-mir-145 Neuropathic Pain 29162479 MiR-145 ameliorates neuropathic pain via inhibiting inflammatory responses and mTOR signaling pathway by targeting Akt3 in a rat model. target gene hsa-mir-20b Prostate Neoplasms 29163708 miR-20b promotes cellular proliferation and migration by directly regulating phosphatase and tensin homolog in prostate cancer target gene hsa-mir-34a Congenital Heart Diseases 29175286 miR-34a increases the risk of CHD through its downregulation of NOTCH-1 by modulating the Notch signaling pathway target gene hsa-mir-23a "Carcinoma, Hepatocellular" 29176948 The Oncogenic Role of Tribbles 1 in Hepatocellular Carcinoma Is Mediated by a Feedback Loop Involving microRNA-23a and p53 target gene hsa-mir-21 Cervical Neoplasms 29177591 "MicroRNA-21 promotes proliferation, migration, and invasion of cervical cancer through targeting TIMP3" target gene hsa-mir-326 Multiple Sclerosis 29181619 MicroRNA-326 contributes to autoimmune thyroiditis by targeting the Ets-1 protein target gene hsa-mir-122 Chronic Hepatitis C 29182758 miR-122 regulates ALDOB and PKM2 expression at the mRNA level target gene hsa-mir-146a Osteoarthritis 29183039 MiR-146a Aggravates LPS-Induced Inflammatory Injury by Targeting CXCR4 in the Articular Chondrocytes target gene hsa-mir-519d "Carcinoma, Breast" 29188531 MiR-519d-3p suppresses breast cancer cell growth and motility via targeting LIM domain kinase 1. target gene hsa-mir-34a "Squamous Cell Carcinoma, Esophageal" 29190930 MicroRNA-34a functions as a tumor suppressor by directly targeting oncogenic PLCE1 in Kazakh esophageal squamous cell carcinoma target gene hsa-mir-361 Obesity 29191698 MicroRNAs-361-5p and miR-574-5p associate with human adipose morphology and regulate EBF1 expression in white adipose tissue. target gene hsa-mir-574 Obesity 29191698 MicroRNAs-361-5p and miR-574-5p associate with human adipose morphology and regulate EBF1 expression in white adipose tissue. target gene hsa-mir-19a Multiple Myeloma 29201171 the results of the present study indicate that targets genes of miR-19a are potential candidate biomarkers for MM target gene hsa-mir-513a Lung Neoplasms 29204818 Mir-513a-3p contributes to the controlling of cellular migration processes in the A549 lung tumor cells by modulating integrin ¦Â-8 expression. target gene hsa-mir-6869 Colorectal Carcinoma 29206292 MicroRNA-6869-5p acts as a tumor suppressor via targeting TLR4/NF-¦ÊB signaling pathway in colorectal cancer. target gene hsa-mir-26a Osteoarthritis 29208566 miR-26a/-26b/FUT4/NF-¦ÊB axis may serve as a predictive biomarker and a potential therapeutic target in OA treatment target gene hsa-mir-1202 "Carcinoma, Hepatocellular" 29217161 MiR-1202 suppresses hepatocellular carcinoma cells migration and invasion by targeting cyclin dependent kinase 14 target gene hsa-mir-200a "Carcinoma, Breast, Triple Negative" 29217458 The identified IMP2/3-miR-200a-PR axis represents a novel double-negative feedback loop and serves as a new potential therapeutic target for the treatment of TNBC target gene hsa-mir-200c Lung Neoplasms 29219949 A miRNA-200c/cathepsin L feedback loop determines paclitaxel resistance in human lung cancer A549 cells in vitro through regulating epithelial-mesenchymal transition. target gene hsa-mir-210 Glioblastoma 29226333 "p53 and miR-210 regulated NeuroD2, a neuronal basic helix-loop-helix transcription factor, is downregulated in glioblastoma patients and functions as a tumor suppressor under hypoxic microenvironment" target gene hsa-mir-182 Atherosclerosis 29226948 MiR-182-5p inhibited oxidative stress and apoptosis triggered by oxidized low-density lipoprotein via targeting toll-like receptor 4. target gene hsa-mir-29c Hyperlipidemia 29226968 Study of microRNAs targeted Dvl2 on the osteoblasts differentiation of rat BMSCs in hyperlipidemia environment. target gene hsa-mir-155 Kidney Neoplasms 29228417 "Inhibition of miR-155 increased GSK-3¦Â expression, attenuated Wnt/¦Â-catenin signaling pathway, weakened proliferation and invasion, and facilitated apoptosis in renal carcinoma cells" target gene hsa-mir-21 Glioblastoma 29228449 miR-21 enhances the resistance of human glioma cells to BCNU by decreasing the expression of Spry2 protein target gene hsa-mir-21 Glioma 29228450 MiR-21 enhanced glioma cells resistance to carmustine via decreasing Spry2 expression target gene hsa-mir-143 Melanoma 29230879 "These results support a functional role for miR-143-5p in regulating alpaca melanocyte migration, proliferation and melanogenesis through direct targeting of TAK1" target gene hsa-mir-150 "Squamous Cell Carcinoma, Head and Neck" 29233721 Antitumor miR-150-5p and miR-150-3p inhibit cancer cell aggressiveness by targeting SPOCK1 in head and neck squamous cell carcinoma. target gene hsa-mir-124 Gastric Neoplasms 29234151 "SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis" target gene hsa-mir-340 Gastric Neoplasms 29234151 "SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis" target gene hsa-mir-155 "Carcinoma, Hepatocellular" 29234238 miR-155-5p modulates malignant behaviors of hepatocellular carcinoma by directly targeting CTHRC1 and indirectly regulating GSK-3¦Â-involved Wnt/¦Â-catenin signaling target gene hsa-mir-23b Osteoporosis 29234953 Involvement of microRNA-23b in TNF-¦Á-reduced BMSC osteogenic differentiation via targeting runx2 target gene hsa-mir-29a Ischemia-Reperfusion Injury 29238305 MiR-29a Suppresses Spermatogenic Cell Apoptosis in Testicular Ischemia-Reperfusion Injury by Targeting TRPV4 Channels target gene hsa-mir-92a Osteoarthritis 29241192 MiR-92a-3p is an important regulator of ADAMTS-4/5 in human chondrocytes and may contribute to the development of OA target gene hsa-mir-296 "Carcinoma, Cervical" 29241478 MicroRNA-296 Targets Specificity Protein 1 to Suppress Cell Proliferation and Invasion in Cervical Cancer. target gene hsa-mir-203 Inflammation 29242191 The inducible microRNA-203 in fish represses the inflammatory responses to Gram-negative bacteria by targeting IL-1 receptor-associated kinase 4 target gene hsa-mir-185 Cleidocranial Dysplasia 29242628 Mutant Runx2 regulates amelogenesis and osteogenesis through a miR-185-5p-Dlx2 axis. target gene hsa-mir-24 Atherosclerosis 29250154 MicroRNA-24 inhibits the proliferation and migration of endothelial cells in patients with atherosclerosis by targeting importin-¦Á3 and regulating inflammatory responses target gene hsa-mir-25 "Squamous Cell Carcinoma, Esophageal" 29250158 "PTEN, TP53, MDM2, E2F1, PRMT5, MCM2, RB1, CDKN1A, SHAD7 and EZH2 may be targeted by the miR-106b-25 cluster, and act together to regulate the development of ESCC" target gene hsa-mir-21 Liver Cirrhosis 29250171 The miRNA-target regulatory network may provide additional insight into the current data regarding the role of miRNAs in liver cirrhosis target gene hsa-mir-29a Retinoblastoma 29251322 miR-29a inhibits human retinoblastoma progression by targeting STAT3 target gene hsa-mir-21 "Carcinoma, Hepatocellular" 29253196 miR-122 participates in the regulation of HCC cell apoptosis through modulating the miR-21-targeted programmed cell death 4 (PDCD4) signal pathway target gene hsa-mir-140 "Carcinoma, Renal Cell, Clear-Cell" 29253611 "miRNA-429, miRNA-206, and miRNA-184 and their target gene CCND1, as well as miRNA-140-3p and miRNA-142-5p and their target gene ATP1B1, might play key roles in ccRCC progression and could be useful biomarkers during ccRCC development" target gene hsa-mir-142 "Carcinoma, Renal Cell, Clear-Cell" 29253611 "miRNA-429, miRNA-206, and miRNA-184 and their target gene CCND1, as well as miRNA-140-3p and miRNA-142-5p and their target gene ATP1B1, might play key roles in ccRCC progression and could be useful biomarkers during ccRCC development" target gene hsa-mir-184 "Carcinoma, Renal Cell, Clear-Cell" 29253611 "miRNA-429, miRNA-206, and miRNA-184 and their target gene CCND1, as well as miRNA-140-3p and miRNA-142-5p and their target gene ATP1B1, might play key roles in ccRCC progression and could be useful biomarkers during ccRCC development" target gene hsa-mir-206 "Carcinoma, Renal Cell, Clear-Cell" 29253611 "miRNA-429, miRNA-206, and miRNA-184 and their target gene CCND1, as well as miRNA-140-3p and miRNA-142-5p and their target gene ATP1B1, might play key roles in ccRCC progression and could be useful biomarkers during ccRCC development" target gene hsa-mir-429 "Carcinoma, Renal Cell, Clear-Cell" 29253611 "miRNA-429, miRNA-206, and miRNA-184 and their target gene CCND1, as well as miRNA-140-3p and miRNA-142-5p and their target gene ATP1B1, might play key roles in ccRCC progression and could be useful biomarkers during ccRCC development" target gene hsa-let-7g Atherosclerosis 29254143 Let-7g suppresses both canonical and non-canonical NF-¦ÊB pathways in macrophages leading to anti-atherosclerosis target gene hsa-mir-182 Osteosarcoma 29254169 "MicroRNA-182 downregulates Wnt/¦Â-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9" target gene hsa-mir-29b Breast Neoplasms 29256222 "MiRNA-29b can inhibit the proliferation, invasion and metastasis of breast cancer cells by inhibiting the expression of RTKN" target gene hsa-mir-296 Melanoma 29260433 Coordinated targeting of MMP-2/MMP-9 by miR-296-3p/FOXCUT exerts tumor-suppressing effects in choroidal malignant melanoma. target gene hsa-mir-188 Glioma 29268818 miR-188 Inhibits Glioma Cell Proliferation and Cell Cycle Progression Through Targeting ¦Â-Catenin. target gene hsa-mir-143 Cervical Neoplasms 29271989 MicroRNA-143 regulates the proliferation and apoptosis of cervical cancer cells by targeting HIF-1¦Á target gene hsa-mir-181a Thyroid Neoplasms 29271997 MiR-181a promotes growth of thyroid cancer cells by targeting tumor suppressor RB1 target gene hsa-mir-30e Parkinson Disease 29274035 MicroRNA-30e regulates neuroinflammation in MPTP model of Parkinson's disease by targeting Nlrp3. target gene hsa-mir-146b Psoriasis 29279330 MicroRNA-146 and cell trauma down-regulate expression of the psoriasis-associated atypical chemokine receptor ACKR2 target gene hsa-mir-34a Neoplasms [unspecific] 29285066 miR-34a may serve an important role in hyperthermia-regulated apoptosis and proliferation in HCT116 cells by influencing the transcriptional activity of p53 target gene hsa-mir-34a "Squamous Cell Carcinoma, Skin or Unspecific" 29285100 "MicroRNA-34a directly targets high-mobility group box 1 and inhibits the cancer cell proliferation, migration and invasion in cutaneous squamous cell carcinoma" target gene hsa-mir-200c "Carcinoma, Gastric" 29286062 "miR-200c regulates the proliferation, apoptosis and invasion of gastric carcinoma cells through the downregulation of EDNRA expression" target gene hsa-mir-124a Liver Neoplasms 29286137 MicroRNA-124a inhibits cell proliferation and migration in liver cancer by regulating interleukin-11 target gene hsa-mir-146a Inflammation 29288795 miR-146a inhibits inflammatory cytokine production in B cells through directly targeting IRAK1 target gene hsa-mir-34a Huntington Disease 29289683 Perturbations in the p53/miR-34a/SIRT1 pathway in the R6/2 Huntington's disease model target gene hsa-mir-206 "Carcinoma, Ovarian" 29291022 NFE2L2/NRF2 silencing-inducible miR-206 targets c-MET/EGFR and suppresses BCRP/ABCG2 in cancer cells target gene hsa-mir-346 "Carcinoma, Hepatocellular" 29295726 miR-346 Promotes HCC Progression by Suppressing Breast Cancer Metastasis Suppressor 1 Expression. target gene hsa-mir-136 "Carcinoma, Hepatocellular" 29295728 miR-136 Inhibits Malignant Progression of Hepatocellular Carcinoma Cells by Targeting Cyclooxygenase 2. target gene hsa-mir-34a "Carcinoma, Hepatocellular" 29298665 "Our results may lead researchers to understand the molecular mechanism of miR-34a in the diagnosis, prognosis and therapy of HCC" target gene hsa-mir-34a Cataract 29299142 MicroRNA-34a promotes mitochondrial dysfunction-induced apoptosis in human lens epithelial cells by targeting Notch2 target gene hsa-mir-19a Osteoarthritis 29306212 MicroRNA-19a promotes cell viability and migration of chondrocytes via up-regulating SOX9 through NF-¦ÊB pathway target gene hsa-mir-137 Melanoma 29307109 miR-137 inhibits melanoma cell proliferation through downregulation of GLO1 target gene hsa-mir-373 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 29307338 Expression of miR-373 and its predicted target genes E-cadherin and CD44 in patients with laryngeal squamous cell carcinoma target gene hsa-mir-34a Osteosarcoma 29312491 MicroRNA-34a promotes cell cycle arrest and apoptosis and suppresses cell adhesion by targeting DUSP1 in osteosarcoma. target gene hsa-mir-423 "Carcinoma, Hepatocellular" 29312509 MicroRNA-423 enhances the invasiveness of hepatocellular carcinoma via regulation of BRMS1 target gene hsa-mir-492 Hepatoblastoma 29314711 MiR-492 regulates metastatic properties of hepatoblastoma via CD44 target gene hsa-mir-26a Inflammation 29315680 "the effect of bta-miR-26a in mastitis, mediated at least in part by enhancing FGA expression, involves host defense, inflammation and tissue damage" target gene hsa-mir-21 Glioma 29316313 MicroRNA-21 promotes glioma cell proliferation and inhibits senescence and apoptosis by targeting SPRY1 via the PTEN/PI3K/AKT signaling pathway target gene hsa-mir-22 "Squamous Cell Carcinoma, Oral" 29319163 "MicroRNA-22 suppresses cell proliferation, migration and invasion in oral squamous cell carcinoma by targeting NLRP3." target gene hsa-mir-125b "Diabetes Mellitus, Type 2" 29319168 Hepatic miR-125b inhibits insulin signaling pathway by targeting PIK3CD. target gene hsa-mir-143 Gastric Neoplasms 29321084 miR-143 inhibits cell proliferation of gastric cancer cells through targeting GATA6 target gene hsa-mir-519d "Carcinoma, Cervical" 29321085 MicroRNA-519d-3p Inhibits Proliferation and Promotes Apoptosis by Targeting HIF-2¦Á in Cervical Cancer Under Hypoxic Conditions. target gene hsa-mir-29a Mitochondrial Metabolism Disease 29322081 Data of expression status of miR-29a and its putative target mitochondrial apoptosis regulatory gene DRP1 upon miR-15a and miR-214 inhibition target gene hsa-mir-150 Neuropathic Pain 29323698 It was revealed that XIST/miR-150/ZEB1 axis can be provided as a therapeutic target in neuropathic pain target gene hsa-mir-501 Autosomal Dominant Polycystic Kidney Disease 29323708 MicroRNA501-5p induces p53 proteasome degradation through the activation of the mTOR/MDM2 pathway in ADPKD cells. target gene hsa-mir-15b Glioma 29323737 MiR-15b/HOTAIR/p53 form a regulatory loop that affects the growth of glioma cells target gene hsa-mir-145 Atherosclerosis 29324316 MicroRNA-145 alleviates high glucose-induced proliferation and migration of vascular smooth muscle cells through targeting ROCK1 target gene hsa-mir-21 "Carcinoma, Salivary Adenoid Cystic" 29328455 "miR-21 may promote SACC progression via PDCD4, PTEN and Bcl-2" target gene hsa-mir-200a Breast Neoplasms 29329575 MicroRNA-200a confers chemoresistance by antagonizing TP53INP1 and YAP1 in human breast cancer target gene hsa-mir-195 Heart Failure 29330215 increased levels of miR-195 in failing myocardium regulate a novel pathway that involves direct SIRT3 suppression and enzymatic inhibition via increased acetylation of PDH and ATP synthase that are essential for cardiac energy metabolism target gene hsa-mir-301a Prostate Neoplasms 29331421 Hyperglycaemia-induced miR-301a promotes cell proliferation by repressing p21 and Smad4 in prostate cancer. target gene hsa-mir-494 Diabetes Mellitus 29333131 miR-494 protects pancreatic ¦Â-cell function by targeting PTEN in gestational diabetes mellitus target gene hsa-mir-155 Melanoma 29333944 MiR-155 Promotes Uveal Melanoma Cell Proliferation and Invasion by Regulating NDFIP1 Expression target gene hsa-mir-21 Asthma 29334241 Disordered expression of genes under the regulation of miRNAs may play an important role in CARAS target gene hsa-mir-21 Autism Spectrum Disorder 29334241 Disordered expression of genes under the regulation of miRNAs may play an important role in CARAS target gene hsa-mir-92a Asthma 29334241 Disordered expression of genes under the regulation of miRNAs may play an important role in CARAS target gene hsa-mir-92a Autism Spectrum Disorder 29334241 Disordered expression of genes under the regulation of miRNAs may play an important role in CARAS target gene hsa-mir-93 Asthma 29334241 Disordered expression of genes under the regulation of miRNAs may play an important role in CARAS target gene hsa-mir-93 Autism Spectrum Disorder 29334241 Disordered expression of genes under the regulation of miRNAs may play an important role in CARAS target gene hsa-mir-144 Osteoporosis 29334613 Reduced miR-144-3p expression in serum and bone mediates osteoporosis pathogenesis by targeting RANK. target gene hsa-mir-181a Preeclampsia 29339719 miR-181a-5p suppresses invasion and migration of HTR-8/SVneo cells by directly targeting IGF2BP2. target gene hsa-mir-19 Glioma 29340016 MiR-19 regulates the proliferation and invasion of glioma by RUNX3 via ¦Â-catenin/Tcf-4 signaling target gene hsa-mir-34a "Carcinoma, Hepatocellular" 29344126 microRNA-34a overexpression inhibits cell migration and invasion via regulating SIRT1 in hepatocellular carcinoma target gene hsa-mir-10a "Carcinoma, Thyroid, Follicular" 29344146 "Network analysis indicated a co-regulatory association between miR-296-5p, miR-10a, miR-139-5p, miR-452, miR-493, miR-7, miR-137, miR-144, miR-145 and corresponding targeted mRNAs, including TNF receptor superfamily member 11b, benzodiazepine receptor (peripheral) -associated protein 1, and transforming growth factor ¦Â receptor 2" target gene hsa-mir-137 "Carcinoma, Thyroid, Follicular" 29344146 "Network analysis indicated a co-regulatory association between miR-296-5p, miR-10a, miR-139-5p, miR-452, miR-493, miR-7, miR-137, miR-144, miR-145 and corresponding targeted mRNAs, including TNF receptor superfamily member 11b, benzodiazepine receptor (peripheral) -associated protein 1, and transforming growth factor ¦Â receptor 2" target gene hsa-mir-139 "Carcinoma, Thyroid, Follicular" 29344146 "Network analysis indicated a co-regulatory association between miR-296-5p, miR-10a, miR-139-5p, miR-452, miR-493, miR-7, miR-137, miR-144, miR-145 and corresponding targeted mRNAs, including TNF receptor superfamily member 11b, benzodiazepine receptor (peripheral) -associated protein 1, and transforming growth factor ¦Â receptor 2" target gene hsa-mir-144 "Carcinoma, Thyroid, Follicular" 29344146 "Network analysis indicated a co-regulatory association between miR-296-5p, miR-10a, miR-139-5p, miR-452, miR-493, miR-7, miR-137, miR-144, miR-145 and corresponding targeted mRNAs, including TNF receptor superfamily member 11b, benzodiazepine receptor (peripheral) -associated protein 1, and transforming growth factor ¦Â receptor 2" target gene hsa-mir-145 "Carcinoma, Thyroid, Follicular" 29344146 "Network analysis indicated a co-regulatory association between miR-296-5p, miR-10a, miR-139-5p, miR-452, miR-493, miR-7, miR-137, miR-144, miR-145 and corresponding targeted mRNAs, including TNF receptor superfamily member 11b, benzodiazepine receptor (peripheral) -associated protein 1, and transforming growth factor ¦Â receptor 2" target gene hsa-mir-296 "Carcinoma, Thyroid, Follicular" 29344146 "Network analysis indicated a co-regulatory association between miR-296-5p, miR-10a, miR-139-5p, miR-452, miR-493, miR-7, miR-137, miR-144, miR-145 and corresponding targeted mRNAs, including TNF receptor superfamily member 11b, benzodiazepine receptor (peripheral) -associated protein 1, and transforming growth factor ¦Â receptor 2" target gene hsa-mir-452 "Carcinoma, Thyroid, Follicular" 29344146 "Network analysis indicated a co-regulatory association between miR-296-5p, miR-10a, miR-139-5p, miR-452, miR-493, miR-7, miR-137, miR-144, miR-145 and corresponding targeted mRNAs, including TNF receptor superfamily member 11b, benzodiazepine receptor (peripheral) -associated protein 1, and transforming growth factor ¦Â receptor 2" target gene hsa-mir-493 "Carcinoma, Thyroid, Follicular" 29344146 "Network analysis indicated a co-regulatory association between miR-296-5p, miR-10a, miR-139-5p, miR-452, miR-493, miR-7, miR-137, miR-144, miR-145 and corresponding targeted mRNAs, including TNF receptor superfamily member 11b, benzodiazepine receptor (peripheral) -associated protein 1, and transforming growth factor ¦Â receptor 2" target gene hsa-mir-7 "Carcinoma, Thyroid, Follicular" 29344146 "Network analysis indicated a co-regulatory association between miR-296-5p, miR-10a, miR-139-5p, miR-452, miR-493, miR-7, miR-137, miR-144, miR-145 and corresponding targeted mRNAs, including TNF receptor superfamily member 11b, benzodiazepine receptor (peripheral) -associated protein 1, and transforming growth factor ¦Â receptor 2" target gene hsa-mir-124 Ovarian Neoplasms 29344168 MiR-124 inhibits invasion and induces apoptosis of ovarian cancer cells by targeting programmed cell death 6 target gene hsa-mir-138 "Carcinoma, Renal Cell" 29344205 MicroRNA-138 suppresses cell proliferation and invasion of renal cell carcinoma by directly targeting SOX9 target gene hsa-mir-146a "Carcinoma, Lung, Non-Small-Cell" 29344219 Upregulation of miR-146a increases cisplatin sensitivity of the non-small cell lung cancer A549 cell line by targeting JNK-2 target gene hsa-mir-1827 "Adenocarcinoma, Lung" 29344280 "MiR-378 and MiR-1827 Regulate Tumor Invasion, Migration and Angiogenesis in Human Lung Adenocarcinoma by Targeting RBX1 and CRKL, Respectively" target gene hsa-mir-378 "Adenocarcinoma, Lung" 29344280 "MiR-378 and MiR-1827 Regulate Tumor Invasion, Migration and Angiogenesis in Human Lung Adenocarcinoma by Targeting RBX1 and CRKL, Respectively" target gene hsa-let-7b Hypohidrotic Ectodermal Dysplasia 29344666 Let-7b regulates alpaca hair growth by downregulating ectodysplasin A. target gene hsa-mir-595 "Leukemia, Lymphoblastic, Acute" 29345051 MiR-595 Suppresses the Cellular Uptake and Cytotoxic Effects of Methotrexate by Targeting SLC19A1 in CEM/C1 Cells. target gene hsa-mir-137 Melanoma 29348676 miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma target gene hsa-mir-199a Acute Respiratory Distress Syndrome 29351405 Acute downregulation of miR-199a attenuates sepsis-induced acute lung injury by targeting SIRT1 target gene hsa-mir-182 "Squamous Cell Carcinoma, Head and Neck" 29356167 "there is frequent and concordant upregulation of miR-31, miR-96, and miR-182 during HNSCC and these miRNAs co-target Numb" target gene hsa-mir-31 "Squamous Cell Carcinoma, Head and Neck" 29356167 "there is frequent and concordant upregulation of miR-31, miR-96, and miR-182 during HNSCC and these miRNAs co-target Numb" target gene hsa-mir-96 "Squamous Cell Carcinoma, Head and Neck" 29356167 "there is frequent and concordant upregulation of miR-31, miR-96, and miR-182 during HNSCC and these miRNAs co-target Numb" target gene hsa-mir-16 Pineal Gland Cancer 29359963 Melatonin Inhibits the Proliferation of Gastric Cancer Cells Through Regulating the miR-16-5p-Smad3 Pathway. target gene hsa-mir-15b Prostate Neoplasms 29363862 miR-15b-5p facilitates the tumorigenicity by targeting RECK and predicts tumour recurrence in prostate cancer target gene hsa-mir-30c Pediatric Osteosarcoma 29364496 Biological function of microRNA-30c/SOX9 in pediatric osteosarcoma cell growth and metastasis. target gene hsa-mir-448 Breast Neoplasms 29368542 "miR-448 inhibits cell migration, invasion, and EMT by targeting to the 3'UTR of ZEB1/2" target gene hsa-mir-330 Alzheimer Disease 29369410 "Protective effects of microRNA-330 on amyloid ¦Â-protein production, oxidative stress, and mitochondrial dysfunction in Alzheimer's disease by targeting VAV1 via the MAPK signaling pathway." target gene hsa-mir-424 "Carcinoma, Endometrial" 29371986 "MicroRNA-424/E2F6 feedback loop modulates cell invasion, migration and EMT in endometrial carcinoma" target gene hsa-mir-760 "Carcinoma, Lung, Non-Small-Cell" 29372517 MiR-760 suppresses non-small cell lung cancer proliferation and metastasis by targeting ROS1. target gene hsa-mir-34a Chronic Obstructive Pulmonary Disease 29373969 miR-34a is involved in CSE-induced apoptosis of human pulmonary microvascular endothelial cells by targeting Notch-1 receptor protein target gene hsa-mir-328 Colon Neoplasms 29374351 miR-328 mediates a metabolic shift in colon cancer cells by targeting SLC2A1/GLUT1. target gene hsa-mir-10b "Carcinoma, Hepatocellular" 29375271 MicroRNA-10b regulates epithelial-mesenchymal transition by modulating KLF4/KLF11/Smads in hepatocellular carcinoma target gene hsa-mir-20a "Carcinoma, Lung, Non-Small-Cell" 29375712 MicroRNA-20a promotes proliferation and invasion by directly targeting early growth response 2 in non-small cell lung carcinoma target gene hsa-mir-132 Inflammation 29377244 MicroRNA-132 attenuates LPS-induced inflammatory injury by targeting TRAF6 in neuronal cell line HT-22 target gene hsa-mir-21 Atrial Fibrillation 29380561 These changes can be explained by alterations in the MMP and miR-21/ERK signaling pathways target gene hsa-mir-130a "Carcinoma, Breast" 29384218 microRNA-130a suppresses breast cancer cell migration and invasion by targeting FOSL1 and upregulating ZO-1. target gene hsa-mir-522 Colorectal Carcinoma 29386092 miR-522-3p promotes tumorigenesis in human colorectal cancer via targeting bloom syndrome protein. target gene hsa-mir-383 Lymphoma 29387204 western blot analysis identified zinc finger E-box binding homeobox 2 (ZEB2) as a direct target gene of miR-383 target gene hsa-mir-144 Osteosarcoma 29387244 miR-144 suppresses proliferation and induces apoptosis of osteosarcoma cells via direct regulation of mTOR expression. target gene hsa-mir-138 "Carcinoma, Hepatocellular" 29387246 " miR-138 targeted SP1 to repress the growth, migration and invasion of HCC cells, and may therefore represent a therapeutic target in human HCC" target gene hsa-mir-206 Legg-Calve-Perthes Disease 29387248 Downregulated SOX9 mediated by miR-206 promoted cell apoptosis in Legg-Calv¨¦-Perthes disease. target gene hsa-mir-210 Kidney Injury 29387863 miR-210 protects renal cell against hypoxia-induced apoptosis by targeting HIF-1 alpha target gene hsa-mir-646 Colorectal Carcinoma 29391877 Low-level miR-646 in colorectal cancer inhibits cell proliferation and migration by targeting NOB1 expression target gene hsa-mir-27b Gastric Neoplasms 29393383 "miR-27b may act as a potential biomarker for differentiating patients with GC from healthy controls, and serve as a tumor suppressor in GC by targeting VEGFC" target gene hsa-mir-29b Neuroblastoma 29399057 MicroRNA-29b alleviates oxygen and glucose deprivation/reperfusion-induced injury via inhibition of the p53-dependent apoptosis pathway in N2a neuroblastoma cells target gene hsa-mir-9 "Carcinoma, Hepatocellular" 29399149 MicroRNA-9 enhances sensitivity to cetuximab in epithelial phenotypehepatocellular carcinoma cells through regulation of the eukaryotic translation initiation factor 5A-2 target gene hsa-mir-15a Myeloma 29399181 Downregulation of miRNA-15a and miRNA-16 promote tumor proliferation in multiple myeloma by increasing CABIN1 expression target gene hsa-mir-16 Myeloma 29399181 Downregulation of miRNA-15a and miRNA-16 promote tumor proliferation in multiple myeloma by increasing CABIN2 expression target gene hsa-mir-16 Pituitary Neoplasms 29399695 MicroRNA?16/VEGFR2/p38/NF?¦ÊB signaling pathway regulates cell growth of human pituitary neoplasms. target gene hsa-mir-204 Colorectal Carcinoma 29402343 microRNA-204 inhibits the growth and motility of colorectal cancer cells by downregulation of CXCL8 target gene hsa-mir-127 "Leukemia, Myeloid, Acute" 29402726 "mRNA and miRNA integrative analyses showed aberrant expression of several hub oncogenes appear to be regulated by some miRNAs like miR-127-5p, miR-494, miR-21 and miR-616 in high TET1 expressers" target gene hsa-mir-21 "Leukemia, Myeloid, Acute" 29402726 "mRNA and miRNA integrative analyses showed aberrant expression of several hub oncogenes appear to be regulated by some miRNAs like miR-127-5p, miR-494, miR-21 and miR-616 in high TET1 expressers" target gene hsa-mir-494 "Leukemia, Myeloid, Acute" 29402726 "mRNA and miRNA integrative analyses showed aberrant expression of several hub oncogenes appear to be regulated by some miRNAs like miR-127-5p, miR-494, miR-21 and miR-616 in high TET1 expressers" target gene hsa-mir-616 "Leukemia, Myeloid, Acute" 29402726 "mRNA and miRNA integrative analyses showed aberrant expression of several hub oncogenes appear to be regulated by some miRNAs like miR-127-5p, miR-494, miR-21 and miR-616 in high TET1 expressers" target gene hsa-mir-429 "Carcinoma, Hepatocellular" 29403024 The newly identified miR-429-CRKL axis represents a novel potential therapeutic target for HCC treatment target gene hsa-mir-31 Arteriosclerosis Obliterans 29403548 MicroRNA-31 promotes arterial smooth muscle cell proliferation and migration by targeting mitofusin-2 in arteriosclerosis obliterans of the lower extremitie target gene hsa-mir-101 "Carcinoma, Endometrial" 29404887 MicroRNA-101 inhibits angiogenesis via COX-2 in endometrial carcinoma. target gene hsa-mir-29a Diabetic Retinopathy 29409329 Downregulation of MicroRNA 29a/b exacerbated diabetic retinopathy by impairing the function of M¨¹ller cells via Forkhead box protein O4. target gene hsa-mir-29b Diabetic Retinopathy 29409329 Downregulation of MicroRNA 29a/b exacerbated diabetic retinopathy by impairing the function of M¨¹ller cells via Forkhead box protein O4. target gene hsa-mir-195 "Carcinoma, Lung, Non-Small-Cell" 29416000 miR-195 targets cyclin D3 and survivin to modulate the tumorigenesis of non-small cell lung cancer target gene hsa-mir-143 "Carcinoma, Gallbladder" 29416013 miR-143-3p targeting of ITGA6 suppresses tumour growth and angiogenesis by downregulating PLGF expression via the PI3K/AKT pathway in gallbladder carcinoma. target gene hsa-mir-493 Prostate Neoplasms 29423080 Downregulation of N6-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N6-methyladenosine levels. target gene hsa-mir-199a "Carcinoma, Thyroid, Papillary" 29427661 miR-199a-5p inhibits the progression of papillary thyroid carcinoma by targeting SNAI1. target gene hsa-mir-145 "Squamous Cell Carcinoma, Esophageal" 29430188 The ROR/miR-145/FSCN1 pathway was shown to take part in the metastasis of ESCC. ROR is likely an oncogene biomarker for ESCC early diagnosis and prognosis target gene hsa-mir-152 Ovarian Neoplasms 29434752 MicroRNA-152 inhibits ovarian cancer cell proliferation and migration and may infer improved outcomes in ovarian cancer through targeting FOXP1. target gene hsa-mir-221 Colorectal Carcinoma 29434757 miR-221 inhibits autophagy and targets TP53INP1 in colorectal cancer cells target gene hsa-mir-150 Melanoma 29434838 MicroRNA-150 inhibitors enhance cell apoptosis of melanoma by targeting PDCD4 target gene hsa-mir-125b Breast Neoplasms 29434858 miR-125b regulates the drug-resistance of breast cancer cells to doxorubicin by targeting HAX-1 target gene hsa-mir-34c Laryngeal Neoplasms 29435079 "miR-34c may be involved in the pathogenesis of laryngeal cancer, and BCL2 may be negatively regulated by miR-34c in M4e cell" target gene hsa-mir-340 Thyroid Neoplasms 29441462 Up-regulation of miR-340-5p promotes progression of thyroid cancer by inhibiting BMP4. target gene hsa-mir-150 Prostate Neoplasms 29441850 MiR-150 promotes the cell invasion of prostate cancer cells by directly regulating the expression of p53 target gene hsa-mir-200a Endometrial Neoplasms 29442045 MiR-200a promotes epithelial-mesenchymal transition of endometrial cancer cells by negatively regulating FOXA2 expression target gene hsa-mir-598 Glioblastoma 29444745 MicroRNA-598 Inhibits Cell Proliferation and Invasion of Glioblastoma by Directly Targeting Metastasis Associated in Colon Cancer-1 (MACC1). target gene hsa-mir-365 Stroke 29451327 MicroRNA-365 modulates astrocyte conversion into neuron in adult rat brain after stroke by targeting Pax6. target gene hsa-mir-19b "Carcinoma, Lung, Non-Small-Cell" 29455644 miR-19b enhances proliferation and apoptosis resistance via the EGFR signaling pathway by targeting PP2A and BIM in non-small cell lung cancer target gene hsa-mir-372 Breast Neoplasms 29456685 miR-372 functions as an oncogenic miRNA in breast cancer by targeting LATS2 target gene hsa-mir-144 Gastric Neoplasms 29456712 MicroRNA-144 functions as a tumor suppressor in gastric cancer by targeting cyclooxygenase-2 target gene hsa-mir-4295 Prostate Neoplasms 29457293 Ginsenoside Rh2 inhibits prostate cancer cell growth through suppression of microRNA-4295 that activates CDKN1A. target gene hsa-mir-24 Heart Failure 29457789 miR-24 potently suppresses SCN5A expression and that rs1805126 modulates this regulation target gene hsa-mir-17 "Lymphoma, Burkitt" 29458013 "In contrast to normal B cells, miRNA target genes in BL were enriched for targets of the oncogenic miR-17 to 92 cluster, and were involved mainly in cell cycle and cell death" target gene hsa-mir-18 "Lymphoma, Burkitt" 29458013 "In contrast to normal B cells, miRNA target genes in BL were enriched for targets of the oncogenic miR-17 to 93 cluster, and were involved mainly in cell cycle and cell death" target gene hsa-mir-19a "Lymphoma, Burkitt" 29458013 "In contrast to normal B cells, miRNA target genes in BL were enriched for targets of the oncogenic miR-17 to 94 cluster, and were involved mainly in cell cycle and cell death" target gene hsa-mir-19b-1 "Lymphoma, Burkitt" 29458013 "In contrast to normal B cells, miRNA target genes in BL were enriched for targets of the oncogenic miR-17 to 96 cluster, and were involved mainly in cell cycle and cell death" target gene hsa-mir-20a "Lymphoma, Burkitt" 29458013 "In contrast to normal B cells, miRNA target genes in BL were enriched for targets of the oncogenic miR-17 to 95 cluster, and were involved mainly in cell cycle and cell death" target gene hsa-mir-92-1 "Lymphoma, Burkitt" 29458013 "In contrast to normal B cells, miRNA target genes in BL were enriched for targets of the oncogenic miR-17 to 97 cluster, and were involved mainly in cell cycle and cell death" target gene hsa-mir-204 Colon Neoplasms 29460671 Targeted delivery of miRNA-204-5p by PEGylated polymer nanoparticles for colon cancer therapy target gene hsa-mir-210 Ischemia-Reperfusion Injury 29461605 "miR-210, as an upstream factor, plays a protective role in cardiomyocytes through directly inhibiting the protein expression of its target gene E2F3" target gene hsa-mir-27a Diabetes Mellitus 29462799 miR-27a may contribute to detrusor fibrosis in STZ-induced diabetic rats by targeting PRKAA2 via the TGF-¦Â1/Smad3 signaling pathway target gene hsa-mir-206 Osteosarcoma 29462818 "Effects of MicroRNA-206 on Osteosarcoma Cell Proliferation, Apoptosis, Migration and Invasion by Targeting ANXA2 Through the AKT Signaling Pathway" target gene hsa-mir-31 Colorectal Carcinoma 29463215 miR-31 down-regulated c-MET in DLD-1 colon cancer cells target gene hsa-mir-150 Atherosclerosis 29463607 the decreases in phosphorylated p65 expression and inflammatory cytokine secretion induced by miR-150 ablation were reversed by PDLIM1 knockdown target gene hsa-mir-21 Pancreatic Neoplasms 29464088 "the expression of two miRComb miR-21 predicted targets, PDCD4 and BTG2, was significantly upregulated in these cells in comparison to control PANC-1" target gene hsa-mir-7 Gastric Neoplasms 29467883 "YCS inhibits proliferation and induces apoptosis of GC cells mediated by miR-7 targeting EGFR, which may be one of the mechanisms whereby YZSJD exerts its effects on GC" target gene hsa-mir-96 Bladder Neoplasms 29467898 HERG1 was an important target of miR-96 target gene hsa-mir-17 "Diabetes Mellitus, Type 2" 29477089 miR-17 improved inflammation-induced insulin resistance by suppressing ASK1 expression in macrophages target gene hsa-mir-216b Diabetic Vasculopathy 29477872 MicroRNA-216b actively modulates diabetic angiopathy through inverse regulation on FZD5. target gene hsa-mir-210 Cerebral Ischemia 29478968 miR-210 promoted neovascularization and NPC migration via the SOCS1-STAT3-VEGF-C pathway target gene hsa-mir-330 Ovarian Neoplasms 29485916 S100A7 Regulates Ovarian Cancer Cell Metastasis and Chemoresistance Through MAPK Signaling and Is Targeted by miR-330-5p. target gene hsa-mir-140 Osteoarthritis 29488053 "miR-140-5p/miR-149 Affects Chondrocyte Proliferation, Apoptosis, and Autophagy by Targeting FUT1 in Osteoarthritis." target gene hsa-mir-149 Osteoarthritis 29488053 "miR-140-5p/miR-149 Affects Chondrocyte Proliferation, Apoptosis, and Autophagy by Targeting FUT1 in Osteoarthritis." target gene hsa-mir-150 Evans Syndrome 29488168 miR-150 regulates B lymphocyte in autoimmune hemolytic anemia/Evans syndrome by c-Myb. target gene hsa-mir-378 Osteosarcoma 29490146 MiR-378 promotes the cell proliferation of osteosarcoma through down-regulating the expression of Kruppel-like factor 9. target gene hsa-mir-342 Melanoma 29495972 MicroRNA-342 prohibits proliferation and invasion of melanoma cells by directly targeting Zinc-finger E-box binding homeobox 1 target gene hsa-mir-140 Colorectal Carcinoma 29499953 miR-140 might be a key suppressor of CRC progression and metastasis through inhibiting EMT process by targeting Smad3 target gene hsa-mir-23b Sepsis 29506272 "Inhibition of MicroRNA-23b Attenuates Immunosuppression During Late Sepsis Through NIK, TRAF1, and XIAP." target gene hsa-mir-10b "Carcinoma, Hepatocellular" 29506532 "CADM2, as a new target of miR-10b, promotes tumor metastasis through FAK/AKT pathway in hepatocellular carcinoma" target gene hsa-mir-223 Atopic Dermatitis 29506638 miR-223 participates in AD through upregulating HNMT indirectly to degrade the excessive histamine target gene hsa-mir-3147 Vulvar Squamous Cell Carcinoma 29512734 miR?3147 serves as an oncomiR in vulvar squamous cell cancer via Smad4 suppression. target gene hsa-mir-29c "Carcinoma, Lung, Non-Small-Cell" 29512752 MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA target gene hsa-mir-139 "Carcinoma, Adrenocortical" 29516499 MiR-483-5p and miR-139-5p promote aggressiveness by targeting N-myc downstream-regulated gene family members in adrenocortical cancer. target gene hsa-mir-483 "Carcinoma, Adrenocortical" 29516499 MiR-483-5p and miR-139-5p promote aggressiveness by targeting N-myc downstream-regulated gene family members in adrenocortical cancer. target gene hsa-mir-181a "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 29517349 miR-181a targets GATA6 to inhibit the progression of human laryngeal squamous cell carcinoma. target gene hsa-mir-449a Breast Neoplasms 29518546 LINC0092 was co-expressed with SFRP1 and RGMA and regulated by hsa-miR-449a and hsa-miR-452-5p target gene hsa-mir-452 Breast Neoplasms 29518546 LINC0092 was co-expressed with SFRP1 and RGMA and regulated by hsa-miR-449a and hsa-miR-452-5p target gene hsa-mir-223 Prostate Neoplasms 29518547 MicroRNA-223-3p regulates cell chemo-sensitivity by targeting FOXO3 in prostatic cancer. target gene hsa-mir-23a "Carcinoma, Nasopharyngeal" 29520105 Metastasis-associated miR-23a from nasopharyngeal carcinoma-derived exosomes mediates angiogenesis by repressing a novel target gene TSGA10 target gene hsa-let-7a "Squamous Cell Carcinoma, Tongue" 29523225 "These findings revealed that H19/let-7a/HMGA2/EMT axis plays a critical role in the regulation of TSCC migration and invasion, which may provide a new therapeutic target for TSCC cancers" target gene hsa-mir-223 Viral Myocarditis 29524390 "the data suggest that miR-223 protects against CVB3-induced inflammation and myocardial damage, which may partly attribute to the regulation of macrophage polarization via targeting Pknox1" target gene hsa-mir-128 Glioma 29524580 MicroRNA-128 inhibits proliferation and invasion of glioma cells by targeting COX-2. target gene hsa-mir-124 Cerebrovascular Disease 29530526 Levels of tight junction protein CLDND1 are regulated by microRNA-124 in the cerebellum of stroke-prone spontaneously hypertensive rats target gene hsa-mir-320a Interstitial Cystitis 29531336 "three transcription factors, E2F-1, E2F-2 and TUB, are regulated by miR-320 family miRNAs" target gene hsa-mir-320b Interstitial Cystitis 29531336 "three transcription factors, E2F-1, E2F-2 and TUB, are regulated by miR-321 family miRNAs" target gene hsa-mir-320c Interstitial Cystitis 29531336 "three transcription factors, E2F-1, E2F-2 and TUB, are regulated by miR-322 family miRNAs" target gene hsa-mir-320d Interstitial Cystitis 29531336 "three transcription factors, E2F-1, E2F-2 and TUB, are regulated by miR-323 family miRNAs" target gene hsa-mir-30a "Carcinoma, Gallbladder" 29540696 "MicroRNA-30a-5p inhibits gallbladder cancer cell proliferation, migration and metastasis by targeting E2F7." target gene hsa-mir-124 Angiomyolipoma 29540858 "miR-9-5p, miR-124-3p, and miR-132-3p regulate BCL2L11 in tuberous sclerosis complex angiomyolipoma." target gene hsa-mir-132 Angiomyolipoma 29540858 "miR-9-5p, miR-124-3p, and miR-132-3p regulate BCL2L11 in tuberous sclerosis complex angiomyolipoma." target gene hsa-mir-9 Angiomyolipoma 29540858 "miR-9-5p, miR-124-3p, and miR-132-3p regulate BCL2L11 in tuberous sclerosis complex angiomyolipoma." target gene hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 29541201 "miR-145 suppresses the proliferation, invasion and migration of NSCLC cells by regulating the BAX/BCL-2 ratio and the caspase-3 cascade" target gene hsa-mir-155 Diabetic Peripheral Neuropathy 29545091 MiR-155 targets PTCH1 to mediate endothelial progenitor cell dysfunction caused by high glucose. target gene hsa-mir-205 Rheumatic Heart Diseases 29548280 Hsa miR-205-3p and hsa-miR-3909 were predicted to target the 3'UTR of IL-1¦Â and IL1R1 respectively target gene hsa-mir-3909 Rheumatic Heart Diseases 29548280 Hsa miR-205-3p and hsa-miR-3909 were predicted to target the 3'UTR of IL-1¦Â and IL1R1 respectively target gene hsa-mir-320 Cerebral Ischemia 29549732 MicRNA-320 facilitates the brain parenchyma injury via regulating IGF-1 during cerebral I/R injury in mice. target gene hsa-mir-98 Atherosclerosis 29549823 MicroRNA-98 regulates foam cell formation and lipid accumulation through repression of LOX-1. target gene hsa-mir-424 "Carcinoma, Breast" 29550638 "miR-424-5p regulates cell proliferation, migration and invasion by targeting doublecortin-like kinase 1 in basal-like breast cancer." target gene hsa-mir-125b Osteoarthritis 29550827 miR-125b could play an important role in inflammatory injury of chondrogenic cells and miR-125b affected inflammatory injury of ATDC5 cells via regulating expression of MIP-1¦Á and regulating NF-¦ÊB and JNK signaling pathways target gene hsa-mir-613 "Carcinoma, Hepatocellular" 29551505 MiR-613 functions as tumor suppressor in hepatocellular carcinoma by targeting YWHAZ. target gene hsa-mir-124 Osteosarcoma 29552134 MicroRNA-124 acts as a tumor-suppressive miRNA by inhibiting the expression of Snail2 in osteosarcoma target gene hsa-mir-183 "Carcinoma, Renal Cell" 29552228 MicroRNA-183 promotes the proliferation and metastasis of renal cell carcinoma through targeting Dickkopf-related protein 3 target gene hsa-mir-34a Cardiovascular Diseases [unspecific] 29554593 MiR-34a-5p mediates sevoflurane preconditioning induced inhibition of hypoxia/reoxygenation injury through STX1A in cardiomyocytes. target gene hsa-mir-155 Colorectal Carcinoma 29556299 MicroRNA-155 acts as a tumor suppressor in colorectal cancer by targeting CTHRC1 in vitro target gene hsa-mir-200c "Carcinoma, Lung, Non-Small-Cell" 29557087 Anti-invasive effect of Cyclamen pseudibericum extract on A549 non-small cell lung carcinoma cells via inhibition of ZEB1 mediated by miR-200c target gene hsa-mir-145 Aneurysm 29558369 "miR-145 - pivotal in regulating VSMC plasticity, which is reduced in vascular diseases - was found to control Uhrf1 mRNA translation" target gene hsa-mir-625 Thyroid Neoplasms 29558717 "MicroRNA-625-3p promotes the proliferation, migration and invasion of thyroid cancer cells by up-regulating astrocyte elevated gene 1." target gene hsa-mir-532 Ovarian Neoplasms 29558748 Ginsenoside 20(S)-Rg3 Inhibits the Warburg Effect Via Modulating DNMT3A/ MiR-532-3p/HK2 Pathway in Ovarian Cancer Cells. target gene hsa-mir-199 "Carcinoma, Hepatocellular" 29559347 "MicroRNA-199 suppresses cell proliferation, migration and invasion by downregulating RGS17 in hepatocellular carcinoma." target gene hsa-mir-24 Hyperglycemia 29559348 MicroRNA-24 regulates vascular remodeling via inhibiting PDGF-BB pathway in diabetic rat model. target gene hsa-mir-143 Crohn Disease 29562274 MicroRNA-143 Targets ATG2B to Inhibit Autophagy and Increase Inflammatory Responses in Crohn's Disease target gene hsa-let-7a Hypoxic-Ischemic Encephalopathy 29562785 "The expression levels of the microRNAs (miRs) let-7a and let-7e, known regulators of Casp3, were inversely correlated to Casp3" target gene hsa-let-7e Hypoxic-Ischemic Encephalopathy 29562785 "The expression levels of the microRNAs (miRs) let-7a and let-7e, known regulators of Casp3, were inversely correlated to Casp3" target gene hsa-mir-302a Osteosarcoma 29563995 MicroRNA-302a inhibits osteosarcoma cell migration and invasion by directly targeting IGF-1R. target gene hsa-mir-21 Colon Neoplasms 29564000 Berberine regulates the microRNA-21-ITG¦¢4-PDCD4 axis and inhibits colon cancer viability target gene hsa-mir-155 "Carcinoma, Hepatocellular" 29565484 "MiR-155 targeted and inhibited FoxO3a expression to suppress the BIM, depress caspase-3 and caspase-9 activities, therefore inhibiting the HCC cell apoptosis and facilitating proliferation" target gene hsa-mir-145 Breast Neoplasms 29565493 "MiR-145 affects breast cancer BS524 cell proliferation, infiltration, and migration via positively regulating OCT4 gene expression" target gene hsa-mir-422a Colorectal Carcinoma 29566993 MiR-422a targets MAPKK6 and regulates cell growth and apoptosis in colorectal cancer cells. target gene hsa-mir-149 Neoplasms [unspecific] 29568059 Cell-autonomous and cell non-autonomous downregulation of tumor suppressor DAB2IP by microRNA-149-3p promotes aggressiveness of cancer cells. target gene hsa-mir-128 Neoplasms [unspecific] 29568354 miR-128 inhibits telomerase activity by targeting TERT mRNA target gene hsa-mir-19a Gastric Neoplasms 29568890 miR-19a/b and MeCP2 repress reciprocally to regulate multidrug resistance in gastric cancer cells. target gene hsa-mir-19b Gastric Neoplasms 29568890 miR-19a/b and MeCP2 repress reciprocally to regulate multidrug resistance in gastric cancer cells. target gene hsa-mir-29b Renal Fibrosis 29568897 miR-29b regulates Ang II-induced EMT of rat renal tubular epithelial cells via targeting PI3K/AKT signaling pathway. target gene hsa-mir-124 Acute Kidney Failure 29568906 miR-124/MCP-1 signaling pathway modulates the protective effect of itraconazole on acute kidney injury in a mouse model of disseminated candidiasis. target gene hsa-mir-375 "Fatty Liver, Non-Alcoholic" 29569260 Down-regulation of microRNA-375 regulates adipokines and inhibits inflammatory cytokines by targeting AdipoR2 in non-alcoholic fatty liver disease target gene hsa-mir-491 Gastric Neoplasms 29569792 Downregulation of miR-491-5p promotes gastric cancer metastasis by regulating SNAIL and FGFR4. target gene hsa-mir-17 Neoplasms [unspecific] 29574928 "The role of miR-17/92 family in development and progression of various cancers has been established. The members of this miRNA family have been shown to be over expressed and target various genes within proliferation, metastasis and angiogenesis pathways." target gene hsa-mir-18 Neoplasms [unspecific] 29574928 "The role of miR-17/92 family in development and progression of various cancers has been established. The members of this miRNA family have been shown to be over expressed and target various genes within proliferation, metastasis and angiogenesis pathways." target gene hsa-mir-19a Neoplasms [unspecific] 29574928 "The role of miR-17/92 family in development and progression of various cancers has been established. The members of this miRNA family have been shown to be over expressed and target various genes within proliferation, metastasis and angiogenesis pathways." target gene hsa-mir-19b-1 Neoplasms [unspecific] 29574928 "The role of miR-17/92 family in development and progression of various cancers has been established. The members of this miRNA family have been shown to be over expressed and target various genes within proliferation, metastasis and angiogenesis pathways." target gene hsa-mir-20a Neoplasms [unspecific] 29574928 "The role of miR-17/92 family in development and progression of various cancers has been established. The members of this miRNA family have been shown to be over expressed and target various genes within proliferation, metastasis and angiogenesis pathways." target gene hsa-mir-92-1 Neoplasms [unspecific] 29574928 "The role of miR-17/92 family in development and progression of various cancers has been established. The members of this miRNA family have been shown to be over expressed and target various genes within proliferation, metastasis and angiogenesis pathways." target gene hsa-mir-374b "Carcinoma, Cervical" 29575013 MicroRNA-374b inhibits cervical cancer cell proliferation and induces apoptosis through the p38/ERK signaling pathway by binding to JAM-2. target gene hsa-mir-34a Gastric Neoplasms 29581731 MicroRNA-34a regulates proliferation and apoptosis of gastric cancer cells by targeting silent information regulator 1 target gene hsa-mir-155 Sezary Disease 29582620 HERV-K and HERV-W expression is regulated by mir-155 in S¨¦zary syndrome target gene hsa-mir-9 Metabolic Syndrome 29584810 Identification of miR-9-5p as direct regulator of ABCA1 and HDL-driven reverse cholesterol transport in circulating CD14+ cells of patients with metabolic syndrome. target gene hsa-mir-30a Liver Fibrosis 29587268 "miR-30a inhibits EMT process, at least in part, via reduction of Snai1, leading to the suppression of HSC activation in liver fibrosis" target gene hsa-mir-146a Mesial Temporal Lobe Epilepsy 29590637 modulation of the miR-146a-CFH-IL-1¦Â loop circuit could be a novel therapeutic target for TLE target gene hsa-mir-122 Chronic Hepatitis C 29593672 the liver-specific microRNA-122 (miR-122) binds to two target sites at the 5' end of the viral RNA genome as well as to at least three additional target sites in the coding region and the 3' UTR target gene hsa-mir-326 Sickle Cell Disease 29601850 miR-326 regulates HbF synthesis by targeting EKLF in human erythroid cells. target gene hsa-mir-9 "Carcinoma, Cervical" 29602130 The mechanisms involved in miR-9 regulated apoptosis in cervical cancer by targeting FOXO3. target gene hsa-mir-451a "Fatty Liver, Non-Alcoholic" 29604329 MiR-451a attenuates free fatty acids-mediated hepatocyte steatosis by targeting the thyroid hormone responsive spot 14 gene. target gene hsa-mir-181c Diabetes Mellitus 29605252 miR-181c-3p and -5p promotes high-glucose-induced dysfunction in human umbilical vein endothelial cells by regulating leukemia inhibitory factor. target gene hsa-mir-370 "Squamous Cell Carcinoma, Esophageal" 29605603 Downregulation of microRNA-370 in esophageal squamous-cell carcinoma is associated with cancer progression and promotes cancer cell proliferation via upregulating PIN1. target gene hsa-mir-6086 Cardiovascular Diseases [unspecific] 29605606 Inhibition of hsa-miR-6086 protects human umbilical vein endothelial cells against TNF¦Á-induced proliferation inhibition and apoptosis via CDH5. target gene hsa-mir-204 Neuroblastoma 29610116 Network Modeling of microRNA-mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN. target gene hsa-mir-125b "Meningitis, Pneumococcal" 29611100 "hsa-miR-25-3p and hsa-miR-125b-5p target the transcription factor TEF-1, for which there are binding sites in Il-1¦Â, Ccl 2 , and Ccl 3 genes" target gene hsa-mir-25 "Meningitis, Pneumococcal" 29611100 "hsa-miR-25-3p and hsa-miR-125b-5p target the transcription factor TEF-1, for which there are binding sites in Il-1¦Â, Ccl 2 , and Ccl 3 genes" target gene hsa-mir-7 Breast Neoplasms 29614984 Our data uncovered a crucial role of TINCR-miR-7-KLF4 axis in human breast cancer target gene hsa-mir-140 "Carcinoma, Lung, Non-Small-Cell" 29617683 MiR-140 Expression Regulates Cell Proliferation and Targets PD-L1 in NSCLC target gene hsa-mir-145 Neuroblastoma 29619741 Expression of miR-145 and Its Target Proteins Are Regulated by miR-29b in Differentiated Neurons target gene hsa-mir-29b Neuroblastoma 29619741 Expression of miR-145 and Its Target Proteins Are Regulated by miR-29b in Differentiated Neurons target gene hsa-mir-200a "Carcinoma, Ovarian" 29620165 FOXD1 is targeted by miR-30a-5p and miR-200a-5p and suppresses the proliferation of human ovarian carcinoma cells by promoting p21 expression in a p53-independent manner. target gene hsa-mir-30a "Carcinoma, Ovarian" 29620165 FOXD1 is targeted by miR-30a-5p and miR-200a-5p and suppresses the proliferation of human ovarian carcinoma cells by promoting p21 expression in a p53-independent manner. target gene hsa-mir-31a Hypertension 29620173 Deregulation of microRNA?31a?5p is involved in the development of primary hypertension by suppressing apoptosis of pulmonary artery smooth muscle cells via targeting TP53. target gene hsa-mir-612 "Carcinoma, Bladder" 29620192 Tumor-suppressing effects of microRNA-612 in bladder cancer cells by targeting malic enzyme 1 expression. target gene hsa-mir-130b Lupus Nephritis 29620214 Dysregulation of PTEN caused by the underexpression of microRNA?130b is associated with the severity of lupus nephritis. target gene hsa-mir-149 "Carcinoma, Colon" 29620230 Formononetin inhibits colon carcinoma cell growth and invasion by microRNA?149?mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways. target gene hsa-mir-328 "Carcinoma, Breast" 29620238 miR-328-5p inhibits MDA-MB-231 breast cancer cell proliferation by targeting RAGE. target gene hsa-mir-142 "Carcinoma, Breast" 29620260 MicroRNA?142?5p modulates breast cancer cell proliferation and apoptosis by targeting phosphatase and tensin homolog. target gene hsa-mir-152 Renal Fibrosis 29620271 miR?152 regulates TGF?¦Â1?induced epithelial?mesenchymal transition by targeting HPIP in tubular epithelial cells. target gene hsa-mir-429 Peripheral Nerve Injury 29624520 Inhibition of microRNA-429 attenuates oxygen-glucose deprivation/reoxygenation-induced neuronal injury by promoting expression of GATA-binding protein 4. target gene hsa-mir-675 Osteosarcoma 29626470 Exosomal miR-675 from metastatic osteosarcoma promotes cell migration and invasion by targeting CALN1. target gene hsa-mir-767 "Carcinoma, Hepatocellular" 29627570 Circular RNA hsa_circ_0000673 promotes hepatocellular carcinoma malignance by decreasing miR-767-3p targeting SET. target gene hsa-mir-145 "Carcinoma, Hepatocellular" 29630879 Atorvastatin induces MicroRNA-145 expression in HEPG2 cells via regulation of the PI3K/AKT signalling pathway target gene hsa-mir-4319 Prostate Neoplasms 29633185 Re-expression of microRNA-4319 inhibits growth of prostate cancer via Her-2 suppression. target gene hsa-mir-103a "Carcinoma, Hepatocellular" 29637568 Hepatoma cell-secreted exosomal microRNA-103 increases vascular permeability and promotes metastasis by targeting junction proteins. target gene hsa-mir-26a "Carcinoma, Hepatocellular" 29653269 MicroRNA-26a is a key regulon that inhibits progression and metastasis of c-Myc/EZH2 double high advanced hepatocellular carcinoma. target gene hsa-mir-20a Atherosclerosis 29653364 MicroRNA-20a protects human aortic endothelial cells from Ox-LDL-induced inflammation through targeting TLR4 and TXNIP signaling. target gene hsa-mir-130b Lung Neoplasms 29653464 MicroRNA-130b targets PTEN to induce resistance to cisplatin in lung cancer cells by activating Wnt/¦Â-catenin pathway. target gene hsa-mir-449a Breast Neoplasms 29653747 MiR-449a suppresses cell migration and invasion by targeting PLAGL2 in breast cancer target gene hsa-mir-96 Osteosarcoma 29656060 microRNA-96 acts as a tumor suppressor gene in human osteosarcoma via target regulation of EZRIN target gene hsa-mir-146a Acute Lung Injury 29658581 MicroRNA?146a/Toll?like receptor 4 signaling protects against severe burn?induced remote acute lung injury in rats via anti?inflammation. target gene hsa-mir-96 "Carcinoma, Hepatocellular" 29658604 Oncogenic miR-96-5p inhibits apoptosis by targeting the caspase-9 gene in hepatocellular carcinoma. target gene hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 29658610 Overexpression of IL-9 induced by STAT3 phosphorylation is mediated by miR-155 and miR-21 in chronic lymphocytic leukemia target gene hsa-mir-21 "Leukemia, Lymphocytic, Chronic, B-Cell" 29658610 Overexpression of IL-9 induced by STAT3 phosphorylation is mediated by miR-155 and miR-21 in chronic lymphocytic leukemia target gene hsa-mir-222 Hypertrophic Scar 29658663 microRNA-222 regulates proliferation and apoptosis of fibroblasts in hypertrophic scar via matrix metalloproteinase 1 target gene hsa-mir-223 "Adenocarcinoma, Colon" 29660302 miR-223-RhoB signaling pathway regulates the proliferation and apoptosis of colon adenocarcinoma target gene hsa-mir-92a Diabetes Mellitus 29660330 MiRNA-92a protects pancreatic B-cell function by targeting KLF2 in diabetes mellitus target gene hsa-mir-155 Esophageal Neoplasms 29660336 MicroRNA-155 inversely correlates with esophageal cancer progression through regulating tumor-associated macrophage FGF2 expression. target gene hsa-mir-758 Atherosclerosis 29660520 miR-758 mediates oxLDL-dependent vascular endothelial cell damage by suppressing the succinate receptor SUCNR1. target gene hsa-mir-32 Breast Neoplasms 29661250 "oncogenic miR-32 and miR-92b were identified to suppress IDH1 expression, leading to the inhibition of cell migration and invasion" target gene hsa-mir-92b Breast Neoplasms 29661250 "oncogenic miR-32 and miR-92b were identified to suppress IDH1 expression, leading to the inhibition of cell migration and invasion" target gene hsa-mir-548k Myasthenia Gravis 29661539 miR-548k regulates CXCL13 expression in myasthenia gravis patients with thymic hyperplasia and in Jurkat cells. target gene hsa-mir-27b Mycobacterium tuberculosis Infection 29661829 we revealed a novel role of the miR-27b/Bag2 axis in the regulation of inflammatory response and apoptosis and provide a potential molecular host defense mechanism against mycobacteria target gene hsa-mir-29b Pulmonary Hypertension 29662889 Effect of miR-29b on the Proliferation and Apoptosis of Pulmonary Artery Smooth Muscle Cells by Targeting Mcl-1 and CCND2 target gene hsa-mir-370 Atherosclerosis 29663491 miR-370 can reduce inflammatory reaction and inhibit the ROS production by targeting TLR4 in THP-1 cells target gene hsa-mir-135a Atherosclerosis 29663503 MiR-135a represses oxidative stress and vascular inflammatory events via targeting toll-like receptor 4 in atherogenesis. target gene hsa-mir-21 "Adenocarcinoma, Lung" 29663730 MiR-21 improves invasion and migration of drug-resistant lung adenocarcinoma cancer cell and transformation of EMT through targeting HBP1 target gene hsa-mir-19a Hypertrophy 29664809 MicroRNA-19a/b-3p protect the heart from hypertension-induced pathological cardiac hypertrophy through PDE5A. target gene hsa-mir-19b Hypertrophy 29664809 MicroRNA-19a/b-3p protect the heart from hypertension-induced pathological cardiac hypertrophy through PDE5A. target gene hsa-mir-195 Prostate Neoplasms 29665645 MicroRNA-195 regulates docetaxel resistance by targeting clusterin in prostate cancer target gene hsa-mir-29b Inflammation 29665646 miR-29b could regulate LPS-induced endothelial cells inflammatory injury through regulation of NF-¦ÊB and JNK signaling pathways target gene hsa-mir-30a "Carcinoma, Breast, Triple Negative" 29666469 A p53/miR-30a/ZEB2 axis controls triple negative breast cancer aggressiveness target gene hsa-mir-146a Cor Pulmonale 29667303 miR-146a can negatively feedback regulate PM1 -induced inflammation via NF-¦ÊB signaling pathway in BEAS-2B cells target gene hsa-mir-193a "Carcinoma, Renal Cell" 29667779 "MiR-193a-3p and miR-224 mediate renal cell carcinoma progression by targeting alpha-2,3-sialyltransferase IV and the phosphatidylinositol 3 kinase/Akt pathway." target gene hsa-mir-224 "Carcinoma, Renal Cell" 29667779 "MiR-193a-3p and miR-224 mediate renal cell carcinoma progression by targeting alpha-2,3-sialyltransferase IV and the phosphatidylinositol 3 kinase/Akt pathway." target gene hsa-mir-122 Chronic Hepatitis C 29669014 miR-122 positively regulates HCV replication by a direct interaction with the 5' untranslated region (UTR) of the viral RNA target gene hsa-mir-182 Myocardial Infarction 29671338 Inhibition of miR-182-5p protects cardiomyocytes from hypoxia-induced apoptosis by targeting CIAPIN1. target gene hsa-mir-145 "Carcinoma, Breast, Triple Negative" 29673594 LincRNA-RoR/miR-145 promote invasion and metastasis in triple-negative breast cancer via targeting MUC1. target gene hsa-mir-373 Lung Neoplasms 29673878 Down-regulation of miR-373 increases the radiosensitivity of lung cancer cells by targeting TIMP2. target gene hsa-mir-21 Ischemia-Reperfusion Injury 29674977 the programmed cell death 4 (PDCD4) expression was identified as a target gene of miR-21 target gene hsa-mir-21 Myocardial Infarction 29674977 the programmed cell death 4 (PDCD4) expression was identified as a target gene of miR-21 target gene hsa-mir-375 Allergic Rhinitis 29677549 miR-375 prevents nasal mucosa cells from apoptosis and ameliorates allergic rhinitis via inhibiting JAK2/STAT3 pathway. target gene hsa-mir-577 Osteoarthritis 29678573 Long non-protein coding RNA DANCR functions as a competing endogenous RNA to regulate osteoarthritis progression via miR-577/SphK2 axis. target gene hsa-mir-485 "Carcinoma, Breast" 29678577 miR-485-5p suppresses breast cancer progression and chemosensitivity by targeting survivin. target gene hsa-mir-338 "Carcinoma, Salivary Adenoid Cystic" 29678584 miR-338-5p/3p target LAMC2 to impair motility and invasion of ACC-M and MDA-MB-231?cells target gene hsa-mir-876 "Carcinoma, Hepatocellular" 29679906 MicroRNA-876-5p inhibits epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma by targeting BCL6 corepressor like 1. target gene hsa-mir-485 Colorectal Carcinoma 29680296 MicroRNA-485-5p reduces O-GlcNAcylation of Bmi-1 and inhibits colorectal cancer proliferation. target gene hsa-mir-155 Cardiovascular Diseases [unspecific] 29686722 Analysis of microRNA-155 expression also suggests its intervention in the regulation of eNOS expression. target gene hsa-mir-21 Gastric Neoplasms 29687845 miRNA-21 may promote the growth of gastric cancer cells by adjusting and controlling PTEN/Akt signal passage mediated PEG2 target gene hsa-mir-150 Sepsis 29689269 MiR-150 predicts survival in patients with sepsis and inhibits LPS-induced inflammatory factors and apoptosis by targeting NF-¦ÊB1 in human umbilical vein endothelial cells. target gene hsa-mir-125b Arteriosclerosis Obliterans 29689557 Exogenous miR-125b expression modulated SRF expression and inhibited vascular neointimal formation in balloon-injured rat carotid arteries target gene hsa-mir-34a Breast Neoplasms 29689563 MicroRNA-34a Inhibition of the TLR Signaling Pathway Via CXCL10 Suppresses Breast Cancer Cell Invasion and Migration target gene hsa-mir-96 Diabetic Peripheral Neuropathy 29689688 Swimming Exercise Induced Reversed Expression of miR-96 and Its Target Gene NaV1.3 in Diabetic Peripheral Neuropathy in Rats target gene hsa-mir-222 Liver Neoplasms 29693134 "miRNA?222 promotes liver cancer cell proliferation, migration and invasion and inhibits apoptosis by targeting BBC3." target gene hsa-mir-145 Bladder Neoplasms 29693148 microRNA?145 modulates migration and invasion of bladder cancer cells by targeting N?cadherin. target gene hsa-mir-125 Colorectal Carcinoma 29693153 MicroRNA?125 inhibits RKO colorectal cancer cell growth by targeting VEGF. target gene hsa-mir-221 Myocardial Ischemic-Reperfusion Injury 29693157 MicroRNA?221?3p contributes to cardiomyocyte injury in H2O2?treated H9c2 cells and a rat model of myocardial ischemia?reperfusion by targeting p57. target gene hsa-mir-146a "Carcinoma, Cervical" 29693168 miR-146a promotes cervical cancer cell viability via targeting IRAK1 and TRAF6. target gene hsa-mir-384 "Carcinoma, Breast" 29693185 MicroRNA-384 inhibits the progression of breast cancer by targeting ACVR1. target gene hsa-mir-27a Heart Diseases [unspecific] 29694513 miR-27a protects human mitral valve interstitial cell from TNF-¦Á-induced inflammatory injury via up-regulation of NELL-1. target gene hsa-mir-1307 "Carcinoma, Breast" 29697201 Mir-1307 regulates cisplatin resistance by targeting Mdm4 in breast cancer expressing wild type P53. target gene hsa-mir-382 Diabetic Nephropathy 29701296 Repression of microRNA-382 inhibits glomerular mesangial cell proliferation and extracellular matrix accumulation via FoxO1 in mice with diabetic nephropathy. target gene hsa-mir-223 Colorectal Carcinoma 29701752 MiR-223 promotes the doxorubicin resistance of colorectal cancer cells via regulating epithelial-mesenchymal transition by targeting FBXW7. target gene hsa-mir-98 "Carcinoma, Hepatocellular" 29702181 MiR-98 suppresses the effects of tumor-associated macrophages on promoting migration and invasion of hepatocellular carcinoma cells by regulating IL-10. target gene hsa-mir-19 Osteosarcoma 29702193 miR-19a-mediated downregulation of RhoB inhibits the dephosphorylation of AKT1 and induces osteosarcoma cell metastasis. target gene hsa-mir-124a "Carcinoma, Lung, Non-Small-Cell" 29702194 Tumor suppressive microRNA-124a inhibits stemness and enhances gefitinib sensitivity of non-small cell lung cancer cells by targeting ubiquitin-specific protease 14. target gene hsa-mir-146a Coronavirus Infections 29702211 miR-146a-5p promotes replication of infectious bronchitis virus by targeting IRAK2 and TNFRSF18. target gene hsa-mir-34a Atherosclerosis 29704100 Downregulation of miR-34a promotes endothelial cell growth and suppresses apoptosis in atherosclerosis by regulating Bcl-2. target gene hsa-mir-502 Esophageal Neoplasms 29709473 MiR-502 mediates esophageal cancer cell TE1 proliferation by promoting AKT phosphorylation. target gene hsa-mir-600 Colorectal Carcinoma 29710537 Hsa_circ_0071589 promotes carcinogenesis via the miR-600/EZH2 axis in colorectal cancer. target gene hsa-mir-338 Melanoma 29710538 MiR-338-5p promotes the growth and metastasis of malignant melanoma cells via targeting CD82. target gene hsa-mir-210 Myocardial Infarction 29710553 MicroRNA-210 aggravates hypoxia-induced injury in cardiomyocyte H9c2 cells by targeting CXCR4. target gene hsa-mir-361 "Carcinoma, Thyroid, Papillary" 29710554 MicroRNA-361-5p inhibits papillary thyroid carcinoma progression by targeting ROCK1. target gene hsa-mir-20a "Carcinoma, Cervical" 29710555 Up-regulation of miR-20a by HPV16 E6 exerts growth-promoting effects by targeting PDCD6 in cervical carcinoma cells. target gene hsa-mir-340 Angiosarcoma 29710664 MicroRNA-340 inhibits the growth and invasion of angiosarcoma cells by targeting SIRT7. target gene hsa-mir-30a Giant Cell Tumor of Bone 29710674 Norcantharidin modulates the miR-30a/Metadherin/AKT signaling axis to suppress proliferation and metastasis of stromal tumor cells in giant cell tumor of bone. target gene hsa-mir-10a Glioma 29713056 Immunosuppressive effects of hypoxia-induced glioma exosomes through myeloid-derived suppressor cells via the miR-10a/Rora and miR-21/Pten Pathways. target gene hsa-mir-21 Glioma 29713056 Immunosuppressive effects of hypoxia-induced glioma exosomes through myeloid-derived suppressor cells via the miR-10a/Rora and miR-21/Pten Pathways. target gene hsa-mir-122 Stroke 29715465 Up-regulation of miR-122 protects against neuronal cell death in ischemic stroke through the heat shock protein 70-dependent NF-¦ÊB pathway by targeting FOXO3. target gene hsa-mir-29c Prostate Neoplasms 29715514 Up-regulated miR-29c inhibits cell proliferation and glycolysis by inhibiting SLC2A3 expression in prostate cancer. target gene hsa-mir-146a Human Immunodeficiency Virus Infection 29717615 HIV-1-Induced miR-146a Attenuates Monocyte Migration by Targeting CCL5 in Human Primary Macrophages. target gene hsa-mir-652 Prostate Neoplasms 29721191 MicroRNA-652 induces NED in LNCaP and EMT in PC3 prostate cancer cells. target gene hsa-mir-146 Colorectal Carcinoma 29722931 "miR-146b-5p was shown to increase EMT by targeting Smad4, and the miR-146b-5p-Smad4 cascade regulated EMT in CRC" target gene hsa-mir-146b Colorectal Carcinoma 29722931 "MiR-146b-5p was shown to increase EMT by targeting Smad4, and the miR-146b-5p-Smad4 cascade regulated EMT in CRC" target gene hsa-mir-876 "Carcinoma, Hepatocellular" 29724530 MiR-876-5p acts as an inhibitor in hepatocellular carcinoma progression by targeting DNMT3A. target gene hsa-mir-505 Colorectal Carcinoma 29726011 MiR-505 mediates methotrexate resistance in colorectal cancer by targeting RASSF8. target gene hsa-mir-154 "Squamous Cell Carcinoma, Skin or Unspecific" 29727714 Inhibitory effect of microRNA-154 targeting WHSC1 on cell proliferation of human skin squamous cell carcinoma through mediating the P53 signaling pathway. target gene hsa-mir-545 Gastric Neoplasms 29733519 MiRNA-545 negatively regulates the oncogenic activity of EMS1 in gastric cancer. target gene hsa-mir-301b Diabetes Mellitus 29733818 The miR-301b-AMPD3 axis may be a novel therapeutic target for intervening enegy metabolism in diabetic hearts target gene hsa-mir-182 Acute Kidney Failure 29733821 miR-182 enhances acute kidney injury by promoting apoptosis involving the targeting and regulation of TCF7L2/Wnt/¦Â-catenins pathway. target gene hsa-mir-339 "Leukemia, Lymphoblastic, Acute" 29735550 miR-339 Promotes Development of Stem Cell Leukemia/Lymphoma Syndrome via Downregulation of the BCL2L11 and BAX Proapoptotic Genes. target gene hsa-mir-181a Atherosclerosis 29737518 MiR-181a inhibits vascular inflammation induced by ox-LDL via targeting TLR4 in human macrophages. target gene hsa-mir-411 Spinal Cord Injuries 29738767 miR-411 suppresses acute spinal cord injury via downregulation of Fas ligand in rats. target gene hsa-mir-130a "Carcinoma, Breast" 29746865 MiR-130a-3p inhibits migration and invasion by regulating RAB5B in human breast cancer stem cell-like cells. target gene hsa-mir-26a Lung Neoplasms 29746867 MiR-26a-5p potentiates metastasis of human lung cancer cells by regulating ITG¦Â8- JAK2/STAT3 axis. target gene hsa-mir-302e Allergic Asthma 29748238 MiR-302e attenuates allergic inflammation in vitro model by targeting RelA. target gene hsa-mir-129 Wound Healing 29748291 MicroRNA-129 and -335 Promote Diabetic Wound Healing by Inhibiting Sp1-Mediated MMP-9 Expression. target gene hsa-mir-335 Wound Healing 29748291 MicroRNA-129 and -335 Promote Diabetic Wound Healing by Inhibiting Sp1-Mediated MMP-9 Expression. target gene hsa-mir-215 Hepatitis C Virus Infection 29749134 miR-215 Enhances HCV Replication by Targeting TRIM22 and Inactivating NF-¦ÊB Signaling. target gene hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 29749434 miR?145 inhibits human non?small-cell lung cancer growth by dual-targeting RIOK2 and NOB1. target gene hsa-mir-125a "Carcinoma, Pancreatic" 29749475 "miR-125a induces apoptosis, metabolism disorder and migrationimpairment in pancreatic cancer cells by targeting Mfn2-related mitochondrial fission." target gene hsa-mir-23a "Carcinoma, Pancreatic" 29749476 miR?23a suppresses pancreatic cancer cell progression by inhibiting PLK?1 expression. target gene hsa-mir-486 Osteoarthritis 29749497 miR?486?5p is upregulated in osteoarthritis and inhibits chondrocyte proliferation and migration by suppressing SMAD2. target gene hsa-mir-125b "Squamous Cell Carcinoma, Esophageal" 29749531 MicroRNA-125b inhibits cell proliferation and induces cell apoptosis in esophageal squamous cell carcinoma by targeting BMF. target gene hsa-mir-23b "Squamous Cell Carcinoma, Esophageal" 29750239 MiR-23b-3p induces the proliferation and metastasis of esophageal squamous cell carcinomas cells through the inhibition of EBF3. target gene hsa-mir-150 Colorectal Carcinoma 29750311 MicroRNA-150 inhibits the proliferation and metastasis potential of colorectal cancer cells by targeting iASPP. target gene hsa-mir-196b "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 29753737 miR-196b is a prognostic factor of human laryngeal squamous cell carcinoma and promotes tumor progression by targeting SOCS2. target gene hsa-mir-665 Intervertebral Disc Degeneration 29761869 microRNA-665 promotes the proliferation and matrix degradation of nucleus pulposus through targeting GDF5 in intervertebral disc degeneration. target gene hsa-mir-130 Myocardial Infarction 29761875 miR-130 aggravates acute myocardial infarction-induced myocardial injury by targeting PPAR-¦Ã. target gene hsa-mir-216a Melanoma 29763606 MiR-216a-5p/Hexokinase 2 axis regulates uveal melanoma growth through modulation of Warburg effect. target gene hsa-mir-141 Gastric Cardia Adenocarcinoma 29765447 MicroRNA-141 inhibits proliferation of gastric cardia adenocarcinoma by targeting MACC1. target gene hsa-mir-142 "Carcinoma, Lung, Non-Small-Cell" 29767245 miR-142-5p regulates CD4+ T cells in human non-small cell lung cancer through PD-L1 expression via the PTEN pathway. target gene hsa-mir-155 Lymphocytic Choriomeningitis 29768211 Long-Term Persistence of Exhausted CD8?T Cells in Chronic Infection Is Regulated by MicroRNA-155. target gene hsa-mir-1247 Pneumonia 29768218 MicroRNA-1247 inhibits lipopolysaccharides-induced acute pneumonia in A549 cells via targeting CC chemokine ligand 16. target gene hsa-mir-520h "Leukemia, Lymphoblastic, Acute" 29768346 "Additionally, POLD1 and MCM2 were found to be regulated by miR-520H via E2F1" target gene hsa-let-7e Dengue Shock Syndrome 29768655 Let-7e inhibits TNF-¦Á expression by targeting the methyl transferase EZH2 in DENV2-infected THP-1 cells. target gene hsa-mir-340 Osteosarcoma 29769415 "Upregulation of microRNA-340 promotes osteosarcoma cell apoptosis while suppressing proliferation, migration and invasion by inactivating the CTNNB1-mediated Notch signaling pathway." target gene hsa-mir-92a "Squamous Cell Carcinoma, Oral" 29772443 MiR-92a regulates oral squamous cell carcinoma (OSCC) cell growth by targeting FOXP1 expression. target gene hsa-mir-1231 Glioma 29774498 MicroRNA-1231 exerts a tumor suppressor role through regulating the EGFR/PI3K/AKT axis in glioma. target gene hsa-mir-7 White Spot Syndrome Virus Infection 29775740 Eriocheir sinensis microRNA-7 targets crab Myd88 to enhance white spot syndrome virus replication. target gene hsa-mir-608 "Carcinoma, Hepatocellular" 29777702 microRNA-608 inhibits human hepatocellular carcinoma cell proliferation via targeting the BET family protein BRD4. target gene hsa-mir-616 Gastric Neoplasms 29777710 MiR-616-3p promotes angiogenesis and EMT in gastric cancer via the PTEN/AKT/mTOR pathway. target gene hsa-mir-129 Ovarian Neoplasms 29777711 UCA1 confers paclitaxel resistance to ovarian cancer through miR-129/ABCB1 axis. target gene hsa-mir-663a "Carcinoma, Gallbladder" 29778567 "EMP3, which is regulated by miR-663a, suppresses gallbladder cancer progression via interference with the MAPK/ERK pathway." target gene hsa-mir-485 Colorectal Carcinoma 29781037 MicroRNA-485 plays tumour-suppressive roles in colorectal cancer by directly targeting GAB2. target gene hsa-mir-1178 Tuberculosis 29781535 MiR-1178 regulates mycobacterial survival and inflammatory responses in Mycobacterium tuberculosis-infected macrophages partly via TLR4. target gene hsa-mir-19a Ovarian Neoplasms 29783075 MiR-19a negatively regulated the expression of PTEN and promoted the growth of ovarian cancer cells. target gene hsa-mir-155 Hypertrophic Scar 29785488 miR-155 inhibits the formation of hypertrophic scar fibroblasts by targeting HIF-1¦Á via PI3K/AKT pathway. target gene hsa-mir-494 Gastric Neoplasms 29786108 miR?494 inhibits cancer?initiating cell phenotypes and reverses resistance to lapatinib by downregulating FGFR2 in HER2?positive gastric cancer. target gene hsa-mir-137 "Diabetes Mellitus, Gestational" 29786111 High glucose suppresses the viability and proliferation of HTR?8/SVneo cells through regulation of the miR?137/PRKAA1/IL?6 axis. target gene hsa-mir-137 Osteoporosis 29786747 MicroRNA-137 dysregulation predisposes to osteoporotic fracture by impeding ALP activity and expression via suppression of leucine-rich repeat-containing G-protein-coupled receptor 4 expression. target gene hsa-mir-20b Ischemia-Reperfusion Injury 29786750 MicroRNA?20b?5p promotes ventricular remodeling by targeting the TGF?¦Â/Smad signaling pathway in a rat model of ischemia?reperfusion injury. target gene hsa-mir-24 Obesity 29787826 Obesity-induced overexpression of miRNA-24 regulates cholesterol uptake and lipid metabolism by targeting SR-B1. target gene hsa-mir-216b Glioma 29787989 Downregulation of microRNA-216b contributes to glioma cell growth and migration by promoting AEG-1-mediated signaling. target gene hsa-mir-320a MALT Lymphoma 29788729 "the TF MYC was a co-target of miR-320a, miR-622, and miR-429" target gene hsa-mir-429 MALT Lymphoma 29788729 "the TF MYC was a co-target of miR-320a, miR-622, and miR-429" target gene hsa-mir-622 MALT Lymphoma 29788729 "the TF MYC was a co-target of miR-320a, miR-622, and miR-429" target gene hsa-mir-378 Diabetic Nephropathy 29792879 Astragaloside suppresses apoptosis of the podocytes in rats with diabetic nephropathy via miR-378/TRAF5 signaling pathway. target gene hsa-mir-20a Toxoplasma gondii Infection 29800695 miR-20a inhibition using locked nucleic acid (LNA) technology and its effects on apoptosis of human macrophages infected by Toxoplasma gondii RH strain. target gene hsa-mir-505 "Carcinoma, Hepatocellular" 29803174 miR-505 enhances doxorubicin-induced cytotoxicity in hepatocellular carcinoma through repressing the Akt pathway by directly targeting HMGB1. target gene hsa-mir-155 Atherosclerosis 29803178 MiR-155 inhibits transformation of macrophages into foam cells via regulating CEH expression. target gene hsa-mir-320a "Carcinoma, Lung, Non-Small-Cell" 29803922 MiR-320a-3p/ELF3 axis regulates cell metastasis and invasion in non-small cell lung cancer via PI3K/Akt pathway. target gene hsa-mir-33a "Squamous Cell Carcinoma, Tongue" 29804249 Long non-coding RNA CASC15 promotes tongue squamous carcinoma progression through targeting miR-33a-5p. target gene hsa-mir-124 Congenital Hypothyroidism 29805523 microRNA-124-3p inhibits the progression of congenital hypothyroidism via targeting programmed cell death protein 6. target gene hsa-mir-128 "Carcinoma, Pancreatic" 29805525 miR-128 induces pancreas cancer cell apoptosis by targeting MDM4. target gene hsa-mir-381 Viral Myocarditis 29805552 MicroRNA-381 protects myocardial cell function in children and mice with viral myocarditis via targeting cyclooxygenase-2 expression. target gene hsa-mir-206 Prostate Neoplasms 29805562 MicroRNA-206 regulates the epithelial-mesenchymal transition and inhibits the invasion and metastasis of prostate cancer cells by targeting Annexin A2. target gene hsa-mir-100 Nasopharyngeal Neoplasms 29805566 miR-100 inhibits the migration and invasion of nasopharyngeal carcinoma by targeting IGF1R. target gene hsa-mir-23a Gastric Neoplasms 29805579 microRNA-23a promotes cell growth and metastasis in gastric cancer via targeting SPRY2-mediated ERK signaling. target gene hsa-mir-128 Osteosarcoma 29805606 Regulatory mechanism of microRNA-128 in osteosarcoma tumorigenesis and evolution through targeting SASH1. target gene hsa-mir-126 Prostate Neoplasms 29805636 MicroRNA-126 inhibits proliferation and metastasis in prostate cancer via regulation of ADAM9. target gene hsa-mir-3160 Prostate Neoplasms 29805667 Prostate cancer cell proliferation is suppressed by microRNA-3160-5p via targeting of F-box and WD repeat domain containing 8. target gene hsa-mir-206 Ovarian Neoplasms 29807226 MiR-206 inhibits epithelial ovarian cancer cells growth and invasion via blocking c-Met/AKT/mTOR signaling pathway. target gene hsa-mir-155 Lichen Planus 29813046 MicroRNA Microarray-Based Identification of Involvement of miR-155 and miR-19a in Development of Oral Lichen Planus (OLP) by Modulating Th1/Th2 Balance via Targeting eNOS and Toll-Like Receptor 2 (TLR2). target gene hsa-mir-19a Lichen Planus 29813046 MicroRNA Microarray-Based Identification of Involvement of miR-155 and miR-19a in Development of Oral Lichen Planus (OLP) by Modulating Th1/Th2 Balance via Targeting eNOS and Toll-Like Receptor 2 (TLR2). target gene hsa-mir-4497 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 29843929 MicroRNA-4497 functions as a tumor suppressor in laryngeal squamous cell carcinoma via negatively modulation the GBX2. target gene hsa-mir-148b Wound Healing 29843955 MicroRNA-148b Targets the TGF-¦Â Pathway to Regulate Angiogenesis and Endothelial-to-Mesenchymal Transition during Skin Wound Healing. target gene hsa-mir-181a Osteoporosis 29845202 Regulatory effects of miRNA?181a on FasL expression in bone marrow mesenchymal stem cells and its effect on CD4+T lymphocyte apoptosis in estrogen deficiency?induced osteoporosis. target gene hsa-mir-148a Endometriosis 29845209 G protein?coupled estrogen receptor/miR?148a/human leukocyte antigen?G signaling pathway mediates cell apoptosis of ovarian endometriosis. target gene hsa-mir-215 Endometrial Neoplasms 29845221 miR?215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancer. target gene hsa-mir-449a "Squamous Cell Carcinoma, Esophageal" 29845226 Downregulation of microRNA?449a?5p promotes esophageal squamous cell carcinoma cell proliferation via cyclin D1 regulation. target gene hsa-mir-19b Melanoma 29845233 Matrine exerts inhibitory effects in melanoma through the regulation of miR-19b-3p/PTEN. target gene hsa-mir-1 Colon Neoplasms 29845255 miR?1 inhibits the progression of colon cancer by regulating the expression of vascular endothelial growth factor. target gene hsa-mir-23a Sepsis 29845275 miR?23a downregulation modulates the inflammatory response by targeting ATG12?mediated autophagy. target gene hsa-mir-183 Osteosarcoma 29845278 Baicalein inhibits osteosarcoma cell proliferation and invasion through the miR?183/Ezrin pathway. target gene hsa-mir-613 Osteosarcoma 29845707 CXCR4-mediated osteosarcoma growth and pulmonary metastasis is suppressed by MicroRNA-613. target gene hsa-mir-193a Gastric Neoplasms 29848678 MiR-193a-5p and -3p Play a Distinct Role in Gastric Cancer: miR-193a-3p Suppresses Gastric Cancer Cell Growth by Targeting ETS1 and CCND1. target gene hsa-mir-203 Oral Neoplasms 29848700 MicroRNA-203 Induces Apoptosis by Targeting Bmi-1 in YD-38 Oral Cancer Cells. target gene hsa-mir-204 Arterial Calcification of Infancy 29850805 Arterial Calcification Is Regulated Via an miR-204/DNMT3a Regulatory Circuit Both In Vitro and in Female Mice. target gene hsa-mir-497 Ischemia-Reperfusion Injury 29852387 MicroRNA-497 promotes proliferation and inhibits apoptosis of cardiomyocytes through the downregulation of Mfn2 in a mouse model of myocardial ischemia-reperfusion injury. target gene hsa-mir-124 Lichen Planus 29852392 Total glucosides of paeony improves the immunomodulatory capacity of MSCs partially via the miR-124/STAT3 pathway in oral lichen planus. target gene hsa-mir-143 Myocardial Infarction 29858017 By Targeting Atg7 MicroRNA-143 Mediates Oxidative Stress-Induced Autophagy of c-Kit+ Mouse Cardiac Progenitor Cells. target gene hsa-mir-106a Osteoarthritis 29858052 Cryptotanshinone Protects Cartilage against Developing Osteoarthritis through the miR-106a-5p/GLIS3 Axis. target gene hsa-mir-411 "Carcinoma, Bladder" 29858066 MicroRNA-411 Downregulation Enhances Tumor Growth by Upregulating MLLT11 Expression in Human Bladder Cancer. target gene hsa-mir-199a "Carcinoma, Hepatocellular" 29858083 miR-199a-3p Modulates MTOR and PAK4 Pathways and Inhibits Tumor Growth in a Hepatocellular Carcinoma Transgenic Mouse Model. target gene hsa-mir-27b Ocular Motility Disease 29858119 Down-regulation of microRNA-27b promotes retinal pigment epithelial cell proliferation and migration by targeting Nox2. target gene hsa-mir-365 Melanoma 29858490 MicroRNA-365 Inhibits Cell Growth and Promotes Apoptosis in Melanoma by Targeting BCL2 and Cyclin D1 (CCND1). target gene hsa-mir-487a "Diabetes Mellitus, Type 1" 29859273 miR-487a-3p upregulated in type 1 diabetes targets CTLA4 and FOXO3. target gene hsa-mir-1179 "Carcinoma, Pancreatic" 29859832 "MicroRNA-1179 inhibits the proliferation, migration and invasion of human pancreatic cancer cells by targeting E2F5." target gene hsa-mir-18a Lung Neoplasms 29860718 Radiosensitizing effects of miR-18a-5p on lung cancer stem-like cells via downregulating both ATM and HIF-1¦Á. target gene hsa-mir-19 "Carcinoma, Breast" 29864457 miR-19 targeting of PTEN mediates butyl benzyl phthalate-induced proliferation in both ER(+) and ER(-) breast cancer cells. target gene hsa-mir-214 "Squamous Cell Carcinoma, Esophageal" 29864623 MiR-214 promotes cell meastasis and inhibites apoptosis of esophageal squamous cell carcinoma via PI3K/AKT/mTOR signaling pathway. target gene hsa-mir-196b Gastric Neoplasms 29864624 MicroRNA-196b enhances the radiosensitivity of SNU-638 gastric cancer cells by targeting RAD23B. target gene hsa-mir-876 Psoriasis 29864894 MiR-876-5p suppresses cell proliferation by targeting Angiopoietin-1 in the psoriasis. target gene hsa-mir-125b "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 29864898 MiR-125b-5p suppressed the glycolysis of laryngeal squamous cell carcinoma by down-regulating hexokinase-2. target gene hsa-mir-23a Pulmonary Hypertension 29864909 MiR-23a regulates the proliferation and migration of human pulmonary artery smooth muscle cells (HPASMCs) through targeting BMPR2/Smad1 signaling. target gene hsa-mir-101 Endometrial Neoplasms 29864910 Berberine suppresses growth and metastasis of endometrial cancer cells via miR-101/COX-2. target gene hsa-mir-129 Neuroblastoma 29864913 miR-129 inhibits tumor growth and potentiates chemosensitivity of neuroblastoma by targeting MYO10. target gene hsa-mir-20a "Carcinoma, Breast, Triple Negative" 29864933 MiRNA-20a-5p promotes the growth of triple-negative breast cancer cells through targeting RUNX3. target gene hsa-mir-200b Metabolic Syndrome 29864940 MicroRNA-200b regulates preadipocyte proliferation and differentiation by targeting KLF4. target gene hsa-mir-300 "Carcinoma, Hepatocellular" 29864952 miR-300 regulates the epithelial-mesenchymal transition and invasion of hepatocellular carcinoma by targeting the FAK/PI3K/AKT signaling pathway. target gene hsa-mir-140 Cardiovascular Diseases [unspecific] 29864954 miR-140-5p aggravates hypoxia-induced cell injury via regulating MLK3 in H9c2 cells. target gene hsa-mir-199a Osteosarcoma 29866054 MiR-199a-3p affects the multi-chemoresistance of osteosarcoma through targeting AK4. target gene hsa-mir-363 "Adenocarcinoma, Cervical" 29871972 MiR-362-3p functions as a tumor suppressor through targeting MCM5 in cervical adenocarcinoma. target gene hsa-mir-1247 "Carcinoma, Bladder" 29872024 Inhibition of miR-1247 on cell proliferation and invasion in bladder cancer through its downstream target of RAB36. target gene hsa-mir-154 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 29874469 MiR-154 inhibits the growth of laryngeal squamous cell carcinoma by targeting the GALNT7. target gene hsa-mir-17 Sciatic Nerve Injury 29877111 PEITC promotes neurite growth in primary sensory neurons via the miR-17-5p/STAT3/GAP-43 axis. target gene hsa-mir-129 Gastric Neoplasms 29879625 MiR-129-5p functions as a tumor suppressor in gastric cancer progression through targeting ADAM9. target gene hsa-mir-21 Periodontitis 29884447 MicroRNA-21 down-regulates inflammation and inhibits periodontitis. target gene hsa-mir-1 "Cardiomyopathy, Hypertrophic" 29885652 Clcn3 as a direct target of miR-1-3p which sheds light on the mechanism of HCM target gene hsa-mir-125a "Adenocarcinoma, Esophageal" 29885883 "microRNA 125a Regulates MHC-I Expression on Esophageal Adenocarcinoma Cells, Associated With Suppression of Antitumor Immune Response and Poor Outcomes of Patients." target gene hsa-mir-206 "Carcinoma, Breast" 29886033 Down-regulation of NAMPT expression by mir-206 reduces cell survival of breast cancer cells. target gene hsa-mir-20a Skin Disease [unspecific] 29886071 MiR-20a-3p regulates TGF-¦Â1/Survivin pathway to affect keratinocytes proliferation and apoptosis by targeting SFMBT1 in vitro. target gene hsa-mir-208a Gastric Neoplasms 29886152 MiR-208a enhances cell proliferation and invasion of gastric cancer by targeting SFRP1 and negatively regulating MEG3. target gene hsa-mir-199a "Leukemia, Myeloid, Chronic" 29890129 microRNA-199a/b-5p enhance imatinib efficacy via repressing WNT2 signaling-mediated protective autophagy in imatinib-resistant chronic myeloid leukemia cells. target gene hsa-mir-199b "Leukemia, Myeloid, Chronic" 29890129 microRNA-199a/b-5p enhance imatinib efficacy via repressing WNT2 signaling-mediated protective autophagy in imatinib-resistant chronic myeloid leukemia cells. target gene hsa-mir-873 Esophageal Neoplasms 29890466 MicroRNA-873 acts as a tumor suppressor in esophageal cancer by inhibiting differentiated embryonic chondrocyte expressed gene 2. target gene hsa-mir-3200 Osteosarcoma 29890825 MicroRNA-3200-5p Promotes Osteosarcoma Cell Invasion via Suppression of BRMS1. target gene hsa-mir-744 Ovarian Neoplasms 29899543 MiR-744-5p inducing cell death by directly targeting HNRNPC and NFIX in ovarian cancer cells. target gene hsa-mir-30a Melanoma 29901141 "miR?30a?5p inhibits the proliferation, migration and invasion of melanoma cells by targeting SOX4." target gene hsa-mir-125b Alzheimer Disease 29901156 MicroRNA?125b regulates Alzheimer's disease through SphK1 regulation. target gene hsa-mir-23b "Carcinoma, Hepatocellular" 29901200 miR?23b inhibits proliferation of SMMC?7721 cells by directly targeting IL?11. target gene hsa-mir-142 Ovarian Neoplasms 29904404 MicroRNA-142-3p inhibits cell proliferation and chemoresistance in ovarian cancer via targeting sirtuin 1. target gene hsa-mir-106b Cholesteatoma 29905392 Down-regulation of exosomal miR-106b-5p derived from cholesteatoma perimatrix fibroblasts promotes angiogenesis in endothelial cells by overexpression of Angiopoietin 2. target gene hsa-mir-149 Diabetes Mellitus 29905828 miR-149 negative regulation of mafA is involved in the arsenite-induced dysfunction of insulin synthesis and secretion in pancreatic beta cells. target gene hsa-mir-145 Idiopathic Scoliosis 29906249 Aberrant miR-145-5p/¦Â-catenin signal impairs osteocyte function in adolescent idiopathic scoliosis. target gene hsa-mir-302c Colorectal Carcinoma 29906744 MicroRNA-302c represses epithelial-mesenchymal transition and metastasis by targeting transcription factor AP-4 in colorectal cancer. target gene hsa-mir-30 Neoplasms [unspecific] 29907771 miR-30 disrupts senescence and promotes cancer by targeting both p16INK4A and DNA damage pathways. target gene hsa-mir-181a Myocardial Infarction 29908129 upregulation of miR-181a suppressed the expression of TGF-¦Â receptor III (T¦ÂRIII) by binding with 3'-UTR target gene hsa-mir-499a Glioma 29908894 MicroRNA-499a decelerates glioma cell proliferation while accelerating apoptosis through the suppression of Notch1 and the MAPK signaling pathway. target gene hsa-mir-590 Crohn Disease 29912317 MicroRNA-590-5p Inhibits Intestinal Inflammation by Targeting YAP. target gene hsa-mir-146a "Carcinoma, Breast" 29915929 Identification of miR-146a is Associated with the Aggressiveness and Suppresses Proliferation via Targeting CDKN2A in Breast Cancer. target gene hsa-mir-590 Osteosarcoma 29916536 miR?590?5p suppresses osteosarcoma cell proliferation and invasion via targeting KLF5. target gene hsa-mir-1297 "Carcinoma, Cervical" 29916735 MicroRNA-1297 contributes to the progression of human cervical carcinoma through PTEN. target gene hsa-mir-324 Polycystic Ovarian Syndrome 29917177 The role of MiR-324-3p in polycystic ovary syndrome (PCOS) via targeting WNT2B. target gene hsa-mir-148a Glioblastoma 29921422 Exosomes of glioma cells deliver miR-148a to promote proliferation and metastasis of glioblastoma via targeting CADM1. target gene hsa-mir-370 "Adenocarcinoma, Colon" 29922946 Hsa-miR-370 inhibited P-selectin-induced cell adhesion in human colon adenocarcinoma cells. target gene hsa-mir-96 "Carcinoma, Bladder" 29923283 miR-96 regulates migration and invasion of bladder cancer through epithelial-mesenchymal transition in response to transforming growth factor-¦Â1. target gene hsa-mir-182 "Carcinoma, Breast" 29925897 miR-182 regulates trastuzumab resistance by targeting MET in breast cancer cells. target gene hsa-mir-197 "Carcinoma, Cervical" 29928375 miR-197 is downregulated in cervical carcinogenesis and suppresses cell proliferation and invasion through targeting forkhead box M1. target gene hsa-mir-216b "Carcinoma, Lung, Non-Small-Cell" 29928377 MicroRNA-216b regulated proliferation and invasion of non-small cell lung cancer by targeting SOX9. target gene hsa-mir-154 "Carcinoma, Lung, Non-Small-Cell" 29928380 MicroRNA-154 functions as a tumor suppressor in non-small cell lung cancer through directly targeting B-cell-specific Moloney murine leukemia virus insertion site 1. target gene hsa-mir-423 Glioma 29928399 MicroRNA-423-3p promotes glioma growth by targeting PANX2. target gene hsa-mir-196b Lung Neoplasms 29928408 miR-196b promotes lung cancer cell migration and invasion through the targeting of GATA6. target gene hsa-mir-449c Gastric Neoplasms 29928430 miR-449c inhibits migration and invasion of gastric cancer cells by targeting PFKFB3. target gene hsa-mir-409 "Squamous Cell Carcinoma, Tongue" 29928443 "miR-409-3p suppresses the proliferation, invasion and migration of tongue squamous cell carcinoma via targeting RDX." target gene hsa-mir-455 "Carcinoma, Renal Cell" 29928475 Anti-tumor roles of both strands of the miR-455 duplex: their targets SKA1 and SKA3 are involved in the pathogenesis of renal cell carcinoma. target gene hsa-mir-146a Lung Neoplasms 29928483 miR-146a suppresses 5-lipoxygenase activating protein (FLAP) expression and Leukotriene B4 production in lung cancer cells. target gene hsa-mir-26a Acute Kidney Failure 29932234 miR-26a modulates HGF and STAT3 effects on the kidney repair process in a glycerol-induced AKI model in rats. target gene hsa-mir-455 Diabetic Nephropathy 29932921 MiR-455-3p suppresses renal fibrosis through repression of ROCK2 expression in diabetic nephropathy. target gene hsa-mir-16 "Carcinoma, Hepatocellular" 29935185 Inhibition of microRNA-16 facilitates the paclitaxel resistance by targeting IKBKB via NF-¦ÊB signaling pathway in hepatocellular carcinoma. target gene hsa-mir-17 Neoplasms [unspecific] 29935344 MicroRNAs of miR-17-92 cluster increase gene expression by targeting mRNA-destabilization pathways. target gene hsa-mir-18 Neoplasms [unspecific] 29935344 MicroRNAs of miR-17-92 cluster increase gene expression by targeting mRNA-destabilization pathways. target gene hsa-mir-19a Neoplasms [unspecific] 29935344 MicroRNAs of miR-17-92 cluster increase gene expression by targeting mRNA-destabilization pathways. target gene hsa-mir-19b-1 Neoplasms [unspecific] 29935344 MicroRNAs of miR-17-92 cluster increase gene expression by targeting mRNA-destabilization pathways. target gene hsa-mir-20a Neoplasms [unspecific] 29935344 MicroRNAs of miR-17-92 cluster increase gene expression by targeting mRNA-destabilization pathways. target gene hsa-mir-92-1 Neoplasms [unspecific] 29935344 MicroRNAs of miR-17-92 cluster increase gene expression by targeting mRNA-destabilization pathways. target gene hsa-mir-340 "Carcinoma, Lung, Non-Small-Cell" 29935356 Lower miR-340 expression predicts poor prognosis of non-small cell lung cancer and promotes cell proliferation by targeting CDK4. target gene hsa-mir-30a Osteosarcoma 29936179 MiR-30a-5p inhibits c cell proliferation and migration by targeting FOXD1. target gene hsa-mir-200a Alzheimer Disease 29936262 Modulation in miR-200a/SIRT1axis is associated with apoptosis in MPP+-induced SH-SY5Y cells. target gene hsa-mir-30a Parkinson Disease 29936662 these DEGs may be regulated by miRNAs of the miR-30 family and TFs STAT1 and GRHL3 target gene hsa-mir-30b Parkinson Disease 29936662 these DEGs may be regulated by miRNAs of the miR-30 family and TFs STAT1 and GRHL3 target gene hsa-mir-30c-1 Parkinson Disease 29936662 these DEGs may be regulated by miRNAs of the miR-30 family and TFs STAT1 and GRHL3 target gene hsa-mir-30c-2 Parkinson Disease 29936662 these DEGs may be regulated by miRNAs of the miR-30 family and TFs STAT1 and GRHL3 target gene hsa-mir-30d Parkinson Disease 29936662 these DEGs may be regulated by miRNAs of the miR-30 family and TFs STAT1 and GRHL3 target gene hsa-mir-30e Parkinson Disease 29936662 these DEGs may be regulated by miRNAs of the miR-30 family and TFs STAT1 and GRHL3 target gene hsa-mir-155 Acute Pancreatitis 29937734 MiRNA-155 Regulates the Th17/Treg Ratio by Targeting SOCS1 in Severe Acute Pancreatitis. target gene hsa-mir-483 Perlman Syndrome 29939354 IGF2-derived miR-483-3p contributes to macrosomia through regulating trophoblast proliferation by targeting RB1CC1. target gene hsa-mir-204 Gastric Neoplasms 29940566 Sensitization of Gastric Cancer Cells to 5-FU by MicroRNA-204 Through Targeting the TGFBR2-Mediated Epithelial to Mesenchymal Transition. target gene hsa-mir-20a Colorectal Carcinoma 29940575 Knockdown of MiR-20a Enhances Sensitivity of Colorectal Cancer Cells to Cisplatin by Increasing ASK1 Expression. target gene hsa-mir-29b-2 "Adenocarcinoma, Pancreatic Ductal" 29940895 MicroRNA-29b-2-5p inhibits cell proliferation by directly targeting Cbl-b in pancreatic ductal adenocarcinoma. target gene hsa-mir-126 Diabetes Mellitus 29942117 Icariside II ameliorates endothelial dysfunction by regulating the MAPK pathway via miR-126/SPRED1 in diabetic human cavernous endothelial cells. target gene hsa-mir-488 "Squamous Cell Carcinoma, Tongue" 29946339 MicroRNA-488 inhibits tongue squamous carcinoma cell invasion and EMT by directly targeting ATF3. target gene hsa-mir-195 Colon Neoplasms 29948330 MiR-195 suppresses colon cancer proliferation and metastasis by targeting WNT3A. target gene hsa-mir-199a Spinal Cord Injuries 29948551 Upregulation of miR-199a-5p Protects Spinal Cord Against Ischemia/Reperfusion-Induced Injury via Downregulation of ECE1 in Rat. target gene hsa-mir-378 Glioma 29949160 "MicroRNA-378 acts as a prognosis marker and inhibits cell migration, invasion and epithelial-mesenchymal transition in human glioma by targeting IRG1." target gene hsa-mir-592 Gastric Neoplasms 29949784 "MiR-592 Promotes Gastric Cancer Proliferation, Migration, and Invasion Through the PI3K/AKT and MAPK/ERK Signaling Pathways by Targeting Spry2." target gene hsa-mir-142 Atherosclerosis 29949787 MicroRNA-142-3p Induces Atherosclerosis-Associated Endothelial Cell Apoptosis by Directly Targeting Rictor. target gene hsa-mir-146b Sepsis 29951922 MiR-146b protect against sepsis induced mice myocardial injury through inhibition of Notch1. target gene hsa-mir-155 Ischemia-Reperfusion Injury 29951932 minocycline is neuroprotective against ischemic brain injury through their modulation of miR-155-mediated BDNF repression target gene hsa-mir-351 Ischemia-Reperfusion Injury 29952043 MicroRNA-351-5p aggravates intestinal ischaemia/reperfusion injury through the targeting of MAPK13 and Sirtuin-6. target gene hsa-mir-26a Idiopathic Pulmonary Fibrosis 29952219 Inhibition of lncRNA PFRL prevents pulmonary fibrosis by disrupting the miR-26a/smad2 loop. target gene hsa-mir-210 Cholangiocarcinoma 29953500 Potential role of HIF-1-responsive microRNA210/HIF3 axis on gemcitabine resistance in cholangiocarcinoma cells. target gene hsa-mir-1287 "Carcinoma, Hepatocellular" 29953647 "Mir-1287 suppresses the proliferation, invasion, and migration in hepatocellular carcinoma by targeting PIK3R3." target gene hsa-mir-146a Liver Fibrosis 29953648 microRNA-146a is involved in rSjP40-inhibited activation of LX-2 cells by targeting Smad4 expression. target gene hsa-mir-34a Liver Fibrosis 29957876 MicroRNA-34a-5p inhibits liver fibrosis by regulating TGF-¦Â1/Smad3 pathway in hepatic stellate cells. target gene hsa-mir-9 "Carcinoma, Head And Neck" 29959873 "MicroRNA-9 inhibits growth and invasion of head and neck cancer cells and is a predictive biomarker of response to plerixafor, an inhibitor of its target CXCR4." target gene hsa-mir-320 Diabetes Mellitus 29960867 miR-320 mediates diabetes amelioration after duodenal-jejunal bypass via targeting adipoR1. target gene hsa-mir-135 "Squamous Cell Carcinoma, Esophageal" 29961392 miR-135 promotes proliferation and stemness of oesophageal squamous cell carcinoma by targeting RERG. target gene hsa-mir-15b Alzheimer Disease 29961672 miR-15b Reduces Amyloid-¦Â Accumulation in SH-SY5Y Cell Line through Targeting NF-¦ÊB signaling and BACE1. target gene hsa-mir-20a Multiple Myeloma 29963125 "Effects of microRNA-20a on the proliferation, migration and apoptosis of multiple myeloma via the PTEN/PI3K/AKT signaling pathway." target gene hsa-mir-139 Prostate Neoplasms 29963147 MicroRNA-139-5P inhibits human prostate cancer cell proliferation by targeting Notch1. target gene hsa-mir-222 "Carcinoma, Ovarian" 29963173 miR-222 promotes invasion and migration of ovarian carcinoma by targeting PTEN. target gene hsa-mir-599 Glioma 29963197 MicroRNA-599 suppresses glioma progression by targeting RAB27B. target gene hsa-mir-328 "Carcinoma, Breast, Triple Negative" 29964098 Dihydrotestosterone regulates expression of CD44 via miR-328-3p in triple-negative breast cancer cells. target gene hsa-mir-144 "Carcinoma, Renal Cell" 29968393 Regulation of antitumor miR-144-5p targets oncogenes: Direct regulation of syndecan-3 and its clinical significance. target gene hsa-mir-760 "Carcinoma, Hepatocellular" 29968951 MicroRNA-760 Inhibits Doxorubicin Resistance in Hepatocellular Carcinoma through Regulating Notch1/Hes1-PTEN/Akt Signaling Pathway. target gene hsa-mir-31 Melanoma 29969627 The miR-31-SOX10 axis regulates tumor growth and chemotherapy resistance of melanoma via PI3K/AKT pathway. target gene hsa-mir-500a "Carcinoma, Hepatocellular" 29969781 MicroRNA-500a Promotes the Progression of Hepatocellular Carcinoma by Post-Transcriptionally Targeting BID. target gene hsa-mir-98 "Adenocarcinoma, Pancreatic Ductal" 29970191 Downregulated miR-98-5p promotes PDAC proliferation and metastasis by reversely regulating MAP4K4. target gene hsa-mir-378 Melanoma 29972255 MicroRNA-378 regulates epithelial-mesenchymal transition and metastasis of melanoma by inhibiting FOXN3 expression through the Wnt/¦Â-catenin pathway. target gene hsa-mir-203a Gastric Neoplasms 29973668 MiR-99b-5p and miR-203a-3p Function as Tumor Suppressors by Targeting IGF-1R in Gastric Cancer. target gene hsa-mir-99b Gastric Neoplasms 29973668 MiR-99b-5p and miR-203a-3p Function as Tumor Suppressors by Targeting IGF-1R in Gastric Cancer. target gene hsa-let-7a Atopic Dermatitis 29974487 "Hsa-let-7a-5p may target CCR7, and hsa-miR-26a-5p probably targets HAS3" target gene hsa-mir-26a Atopic Dermatitis 29974487 "Hsa-let-7a-5p may target CCR7, and hsa-miR-26a-5p probably targets HAS3" target gene hsa-mir-106b "Carcinoma, Hepatocellular" 29975452 MiR-106b regulates the apoptosis and tumorigenesis of hepatocellular carcinoma via targeting Zinc finger and BTB domain-containing protein 7A (Zbtb7a). target gene hsa-mir-137 "Carcinoma, Breast, Triple Negative" 29975921 MiR-137 Suppresses Triple-Negative Breast Cancer Stemness and Tumorigenesis by Perturbing BCL11A-DNMT1 Interaction. target gene hsa-mir-424 "Carcinoma, Hepatocellular" 29975928 "Focusing on the new insight of the PVT1/miR-424-5p/INCENP axis, this study provides a novel perspective for HCC therapeutic strategies" target gene hsa-mir-100 "Carcinoma, Breast" 29975932 miR-100 Reverses Cisplatin Resistance in Breast Cancer by Suppressing HAX-1. target gene hsa-mir-711 Kaposi Sarcoma 29976660 Upregulation of MicroRNA 711 Mediates HIV-1 Vpr Promotion of Kaposi's Sarcoma-Associated Herpesvirus Latency and Induction of Pro-proliferation and Pro-survival Cytokines by Targeting the Notch/NF-¦ÊB-Signaling Axis. target gene hsa-mir-103 Atherosclerosis 29980665 miR-103 promotes endothelial maladaptation by targeting lncWDR59. target gene hsa-mir-340 Age-Related Macular Degeneration 29982095 MiR-340/iASPP axis affects UVB-mediated retinal pigment epithelium (RPE) cell damage. target gene hsa-mir-92a Osteosarcoma 29984257 MiR-92a Inhibits the Progress of Osteosarcoma Cells and Increases the Cisplatin Sensitivity by Targeting Notch1. target gene hsa-mir-498 "Carcinoma, Breast" 29985991 MicroRNA-498 promotes proliferation and migration by targeting the tumor suppressor PTEN in breast cancer cells. target gene hsa-mir-124 "Adenocarcinoma, Pancreatic Ductal" 29988949 Involvement of anti-tumor miR-124-3p and its targets in the pathogenesis of pancreatic ductal adenocarcinoma: direct regulation of ITGA3 and ITGB1 by miR-124-3p. target gene hsa-mir-146a Infection [unspecific] 29990507 MiR-146a-3p and miR-216a-5p inhibited the expression of type-I IFN and the Mx1 gene induced by IHNV target gene hsa-mir-216a Infection [unspecific] 29990507 MiR-146a-3p and miR-216a-5p inhibited the expression of type-I IFN and the Mx1 gene induced by IHNV target gene hsa-mir-193b Liver Injury 29990747 MicroRNA-193b-3p regulates hepatocyte apoptosis in selenium-deficient broilers by targeting MAML1. target gene hsa-mir-298 "Carcinoma, Hepatocellular" 29990836 MicroRNA-298 represses hepatocellular carcinoma progression by inhibiting CTNND1-mediated Wnt/¦Â-catenin signaling. target gene hsa-mir-218 "Squamous Cell Carcinoma, Oral" 29990854 Downregulation of miR-218-5p promotes invasion of oral squamous cell carcinoma cells via activation of CD44-ROCK signaling. target gene hsa-mir-34a Osteosarcoma 29991717 miR-34a exerts as a key regulator in the dedifferentiation of osteosarcoma via PAI-1-Sox2 axis. target gene hsa-mir-223 Osteosarcoma 29991755 "miR-223-5p/(CLSTN2, AC009951.1, LINC01705, AC090673.1), miR-378b/(ALX4, IGSF3, SULF1), and miR-323b-3p/TGFBR3 were involved in both tumorigenesis and pulmonary metastasis of OS." target gene hsa-mir-323b Osteosarcoma 29991755 "miR-223-5p/(CLSTN2, AC009951.1, LINC01705, AC090673.1), miR-378b/(ALX4, IGSF3, SULF1), and miR-323b-3p/TGFBR3 were involved in both tumorigenesis and pulmonary metastasis of OS." target gene hsa-mir-378b Osteosarcoma 29991755 "miR-223-5p/(CLSTN2, AC009951.1, LINC01705, AC090673.1), miR-378b/(ALX4, IGSF3, SULF1), and miR-323b-3p/TGFBR3 were involved in both tumorigenesis and pulmonary metastasis of OS." target gene hsa-mir-186 Alzheimer Disease 29995978 Effect of microRNA-186 on oxidative stress injury of neuron by targeting interleukin 2 through the janus kinase-signal transducer and activator of transcription pathway in a rat model of Alzheimer's disease. target gene hsa-mir-150 Osteoarthritis 29996115 Down-Regulation of MiR-150 Alleviates Inflammatory Injury Induced by Interleukin 1 via Targeting Kruppel-Like Factor 2 in Human Chondrogenic Cells. target gene hsa-mir-17 Prostate Neoplasms 30001402 The deregulation of miR-17/CCND1 axis during neuroendocrine transdifferentiation of LNCaP prostate cancer cells. target gene hsa-mir-34a "Carcinoma, Bladder" 30001529 MicroRNA-34a Attenuates Metastasis and Chemoresistance of Bladder Cancer Cells by Targeting the TCF1/LEF1 Axis. target gene hsa-mir-135b Cerebral Ischemia 30002689 MicroRNA-135b-5p prevents oxygen-glucose deprivation and reoxygenation-induced neuronal injury through regulation of the GSK-3¦Â/Nrf2/ARE signaling pathway. target gene hsa-mir-181b "Carcinoma, Lung, Small-Cell" 30002690 miR-181b inhibits chemoresistance in cisplatin-resistant H446 small cell lung cancer cells by targeting Bcl-2. target gene hsa-mir-874 Ovarian Neoplasms 30004169 Upregulation of miR-874-3p and miR-874-5p inhibits epithelial ovarian cancer malignancy via SIK2. target gene hsa-mir-6126 Hepatitis B Virus Infection 30004437 miR-6126 was able to suppress HBsAg production and HBV replication target gene hsa-mir-34a Fatty Liver [unspecific] 30006135 Ablation of carotenoid cleavage enzymes (BCO1 and BCO2) induced hepatic steatosis by altering the farnesoid X receptor/miR-34a/sirtuin 1 pathway. target gene hsa-mir-9 "Carcinoma, Hepatocellular" 30006781 "miR-9 inhibits the metastatic ability of hepatocellular carcinoma via targeting beta galactoside alpha-2,6-sialyltransferase 1." target gene hsa-mir-15a Diabetes Mellitus 30007975 "experiments in MIN6 cells illustrated that miR-15a, miR-424, miR-497, and miR-185 positively regulated insulin biosynthesis by co-inhibiting UCP2 expression" target gene hsa-mir-185 Diabetes Mellitus 30007975 "experiments in MIN6 cells illustrated that miR-15a, miR-424, miR-497, and miR-185 positively regulated insulin biosynthesis by co-inhibiting UCP2 expression" target gene hsa-mir-424 Diabetes Mellitus 30007975 "experiments in MIN6 cells illustrated that miR-15a, miR-424, miR-497, and miR-185 positively regulated insulin biosynthesis by co-inhibiting UCP2 expression" target gene hsa-mir-497 Diabetes Mellitus 30007975 "experiments in MIN6 cells illustrated that miR-15a, miR-424, miR-497, and miR-185 positively regulated insulin biosynthesis by co-inhibiting UCP2 expression" target gene hsa-mir-204 Glioblastoma 30008822 "miR-204 functions as a tumor suppressor gene, at least partly by suppressing CYP27A1 in glioblastoma." target gene hsa-mir-29c Liver Neoplasms 30008835 MicroRNA-29c restores cisplatin sensitivity in liver cancer through direct inhibition of sirtuin 1 expression. target gene hsa-mir-205 "Carcinoma, Hepatocellular" 30008920 MicroRNA-205 is downregulated in hepatocellular carcinoma and inhibits cell growth and metastasis via directly targeting vascular endothelial growth factor A. target gene hsa-mir-210 Osteosarcoma 30008923 miR-210 promotes human osteosarcoma cell migration and invasion by targeting FGFRL1. target gene hsa-mir-650 Colorectal Carcinoma 30008936 MicroRNA-650 targets inhibitor of growth 4 to promote colorectal cancer progression via mitogen activated protein kinase signaling. target gene hsa-mir-155 Gastric Neoplasms 30008945 Mitogen-activated protein kinase kinase kinase 10 was demonstrated to be a potential target gene of miR-155-5p target gene hsa-mir-638 Glioma 30010402 hsa_circ_0000177-miR-638-FZD7-Wnt Signaling Cascade Contributes to the Malignant Behaviors in Glioma. target gene hsa-mir-106a Colorectal Carcinoma 30011263 miR-106a Reduces 5-Fluorouracil (5-FU) Sensitivity of Colorectal Cancer by Targeting Dual-Specificity Phosphatases 2 (DUSP2). target gene hsa-mir-27b "Carcinoma, Breast" 30012170 Suppression of PDHX by microRNA-27b deregulates cell metabolism and promotes growth in breast cancer. target gene hsa-mir-589 Gastric Neoplasms 30012200 miR-589 promotes gastric cancer aggressiveness by a LIFR-PI3K/AKT-c-Jun regulatory feedback loop. target gene hsa-mir-340 Psoriasis 30012847 miR-340 Alleviates Psoriasis in Mice through Direct Targeting of IL-17A. target gene hsa-mir-488 Osteosarcoma 30015825 "MicroRNA-488 inhibits proliferation, invasion and EMT in osteosarcoma cell lines by targeting aquaporin 3." target gene hsa-mir-655 "Squamous Cell Carcinoma, Oral" 30015840 MicroRNA?655 suppresses cell proliferation and invasion in oral squamous cell carcinoma by directly targeting metadherin and regulating the PTEN/AKT pathway. target gene hsa-mir-199a Testicular Neoplasms 30015851 miR?199a?3p/Sp1/LDHA axis controls aerobic glycolysis in testicular tumor cells. target gene hsa-mir-665 Ovarian Neoplasms 30015865 MicroRNA?665 suppresses the growth and migration of ovarian cancer cells by targeting HOXA10. target gene hsa-mir-155 "Carcinoma, Breast" 30015868 NT21MP negatively regulates paclitaxel-resistant cells by targeting miR?155?3p and miR?155-5p via the CXCR4 pathway in breast cancer. target gene hsa-mir-577 "Carcinoma, Lung, Non-Small-Cell" 30015869 miR-577 suppresses cell proliferation and epithelial-mesenchymal transition by regulating the WNT2B mediated Wnt/¦Â-catenin pathway in non-small cell lung cancer. target gene hsa-mir-200b Colorectal Carcinoma 30015876 miR?200b?3p inhibits proliferation and induces apoptosis in colorectal cancer by targeting Wnt1. target gene hsa-mir-500a Glioblastoma 30015879 "MiR?500a?5p promotes glioblastoma cell proliferation, migration and invasion by targeting chromodomain helicase DNA binding protein 5." target gene hsa-mir-155 Atherosclerosis 30015881 MicroRNA?155 promotes ox?LDL?induced autophagy in human umbilical vein endothelial cells by targeting the PI3K/Akt/mTOR pathway. target gene hsa-mir-185 "Carcinoma, Breast" 30015912 miR?185?5p inhibits F?actin polymerization and reverses epithelial mesenchymal transition of human breast cancer cells by modulating RAGE. target gene hsa-mir-218 Osteoporosis 30016774 MicroRNA-218 Negatively Regulates Osteoclastogenic Differentiation by Repressing the Nuclear Factor-¦ÊB Signaling Pathway and Targeting Tumor Necrosis Factor Receptor 1. target gene hsa-mir-410 "Carcinoma, Breast" 30016800 MiR-410 Acts as a Tumor Suppressor in Estrogen Receptor-Positive Breast Cancer Cells by Directly Targeting ERLIN2 via the ERS Pathway. target gene hsa-mir-148a Thyroid Neoplasms 30018720 PKM2 functions as a potential oncogene and is a crucial target of miR-148a and miR-326 in thyroid tumorigenesis. target gene hsa-mir-326 Thyroid Neoplasms 30018720 PKM2 functions as a potential oncogene and is a crucial target of miR-148a and miR-326 in thyroid tumorigenesis. target gene hsa-mir-92a-1 Bone Disease [unspecific] 30019248 MicroRNA-92a-1-5p influences osteogenic differentiation of MC3T3-E1 cells by regulating ¦Â-catenin. target gene hsa-mir-335 Ovarian Neoplasms 30019389 MiR-335-5p restores cisplatin sensitivity in ovarian cancer cells through targeting BCL2L2. target gene hsa-mir-153 "Carcinoma, Endometrial" 30019459 "miRNAs,including miR-182, miR-183, miR-153, miR-27a, and miR-96, were predicted to bind LINC00261 and FOXO1, and functioned to attenuate expression of LINC00261 and FOXO1" target gene hsa-mir-182 "Carcinoma, Endometrial" 30019459 "miRNAs,including miR-182, miR-183, miR-153, miR-27a, and miR-96, were predicted to bind LINC00261 and FOXO1, and functioned to attenuate expression of LINC00261 and FOXO1" target gene hsa-mir-183 "Carcinoma, Endometrial" 30019459 "miRNAs,including miR-182, miR-183, miR-153, miR-27a, and miR-96, were predicted to bind LINC00261 and FOXO1, and functioned to attenuate expression of LINC00261 and FOXO1" target gene hsa-mir-27a "Carcinoma, Endometrial" 30019459 "miRNAs,including miR-182, miR-183, miR-153, miR-27a, and miR-96, were predicted to bind LINC00261 and FOXO1, and functioned to attenuate expression of LINC00261 and FOXO1" target gene hsa-mir-96 "Carcinoma, Endometrial" 30019459 "miRNAs,including miR-182, miR-183, miR-153, miR-27a, and miR-96, were predicted to bind LINC00261 and FOXO1, and functioned to attenuate expression of LINC00261 and FOXO1" target gene hsa-mir-21a Obesity 30020817 Long Noncoding RNA GAS5 Suppresses 3T3-L1 Cells Adipogenesis Through miR-21a-5p/PTEN Signal Pathway. target gene hsa-mir-298 "Stroke, Ischemic" 30021197 MiR-298 Exacerbates Ischemia/Reperfusion Injury Following Ischemic Stroke by Targeting Act1. target gene hsa-mir-129 "Carcinoma, Thyroid, Papillary" 30021343 MiR-129 regulates growth and invasion by targeting MAL2 in papillary thyroid carcinoma. target gene hsa-mir-149 "Carcinoma, Cervical" 30021347 miR-149 regulates the proliferation and apoptosis of cervical cancer cells by targeting GIT1. target gene hsa-mir-19a "Carcinoma, Hepatocellular" 30021351 microRNA-19a-3p promotes tumor metastasis and chemoresistance through the PTEN/Akt pathway in hepatocellular carcinoma. target gene hsa-mir-15a "Carcinoma, Cervical" 30021370 Over-expression of miR-15a-3p enhances the radiosensitivity of cervical cancer by targeting tumor protein D52. target gene hsa-mir-519d Colorectal Carcinoma 30021381 MicroRNA-519d-3p inhibits cell proliferation and migration by targeting TROAP in colorectal cancer. target gene hsa-mir-373 "Carcinoma, Pancreatic" 30021382 MiR-373-3p enhances the chemosensitivity of gemcitabine through cell cycle pathway by targeting CCND2 in pancreatic carcinoma cells. target gene hsa-mir-363 Colorectal Carcinoma 30021386 MiR-363-3p suppresses tumor growth and metastasis of c via targeting SphK2. target gene hsa-mir-26a Lung Injury [unspecific] 30024304 MicroRNA dysregulation in lung injury: the role of the miR-26a/EphA2 axis in regulation of endothelial permeability. target gene hsa-mir-550a "Carcinoma, Lung, Non-Small-Cell" 30024604 MiR-550a-3p promotes non-small cell lung cancer cell proliferation and metastasis through down-regulating TIMP2. target gene hsa-mir-132 Glioma 30024792 miR-132-3p boosts caveolae-mediated transcellular transport in glioma endothelial cells by targeting PTEN/PI3K/PKB/Src/Cav-1 signaling pathway. target gene hsa-mir-16 Polycystic Ovarian Syndrome 30025387 MicroRNA-16 Promotes Ovarian Granulosa Cell Proliferation and Suppresses Apoptosis Through Targeting PDCD4 in Polycystic Ovarian Syndrome. target gene hsa-mir-29b Cardiac Fibrosis 30025410 MicroRNA-29b Regulates the Mitochondria-Dependent Apoptotic Pathway by Targeting Bax in Doxorubicin Cardiotoxicity. target gene hsa-mir-1296 Colorectal Carcinoma 30026827 "MicroRNA-1296 Facilitates Proliferation, Migration And Invasion Of Colorectal Cancer Cells By Targeting SFPQ." target gene hsa-mir-616 Preeclampsia 30028057 MiR-616-3p modulates cell proliferation and migration through targeting tissue factor pathway inhibitor 2 in preeclampsia. target gene hsa-mir-219a Sepsis 30028330 MicroRNA-219 alleviates glutamate-induced neurotoxicity in cultured hippocampal neurons by targeting calmodulin-dependent protein kinase II gamma. target gene hsa-mir-5590 Gastric Neoplasms 30029874 miR-5590-3p inhibited tumor growth in gastric cancer by targeting DDX5/AKT/m-TOR pathway. target gene hsa-mir-30d Lung Fibrosis 30029934 MicroRNA-30d/JAG1 axis modulates pulmonary fibrosis through Notch signaling pathway. target gene hsa-mir-204 Gastric Neoplasms 30031110 oxaliplatin impairs sensory neurons arborization through up-regulation of miR-204 that decreases PlexinA2 expression and neurite length target gene hsa-mir-181d Osteosarcoma 30031607 miR-181d-5p-FOXP1 feedback loop modulates the progression of osteosarcoma. target gene hsa-mir-140 "Carcinoma, Breast" 30032164 miR-140-5p inhibits the proliferation and enhances the efficacy of doxorubicin to breast cancer stem cells by targeting Wnt1. target gene hsa-mir-181a Glioma 30036882 "Kaiso (ZBTB33) Downregulation by Mirna-181a Inhibits Cell Proliferation, Invasion, and the Epithelial-Mesenchymal Transition in Glioma Cells." target gene hsa-mir-135b Hypertrophy 30037628 Overexpression of miR-135b attenuates pathological cardiac hypertrophy by targeting CACNA1C. target gene hsa-mir-384 Glioma 30038507 MicroRNA-384 inhibits proliferation migration and invasion of glioma by targeting at CDC42. target gene hsa-mir-19b "Carcinoma, Breast" 30038508 miR-19b serves as a prognostic biomarker of breast cancer and promotes tumor progression through PI3K/AKT signaling pathway. target gene hsa-mir-194 Hepatitis B Virus Infection 30044042 MicroRNA-194 protects against chronic hepatitis B-related liver damage by promoting hepatocyte growth via ACVR2B. target gene hsa-mir-324 Hemophilus Influenzae Infection 30045983 MicroRNA hsa-miR-324-5p Suppresses H5N1 Virus Replication by Targeting the Viral PB1 and Host CUEDC2. target gene hsa-mir-26a Rheumatoid Arthritis 30046030 miR-26a-5p Regulates Synovial Fibroblast Invasion in Patients with Rheumatoid Arthritis by Targeting Smad 1. target gene hsa-mir-363 Ovarian Neoplasms 30046387 "miR-363 confers taxane resistance in ovarian cancer by targeting the Hippo pathway member, LATS2." target gene hsa-mir-34a Osteoarthritis 30048987 "MiR-34a Enhances Chondrocyte Apoptosis, Senescence and Facilitates Development of Osteoarthritis by Targeting DLL1 and Regulating PI3K/AKT Pathway." target gene hsa-mir-143 "Leukemia, Myeloid, Acute" 30050105 MicroRNA-143 targets ERK5 in granulopoiesis and predicts outcome of patients with acute myeloid leukemia. target gene hsa-mir-29 "Diabetes Mellitus, Type 2" 30050458 "Among the enriched miRNAs was miR-29, a regulator of GLUT4 mRNA expression" target gene hsa-mir-106 Hyperglycemia 30055307 MicroRNA-106 attenuates hyperglycemia-induced vascular endothelial cell dysfunction by targeting HMGB1. target gene hsa-mir-1273g Colorectal Carcinoma 30056111 miR-1273g silences MAGEA3/6 to inhibit human colorectal cancer cell growth via activation of AMPK signaling. target gene hsa-mir-384 Osteoarthritis 30057417 Inhibition of microRNA-384-5p alleviates osteoarthritis through its effects on inhibiting apoptosis of cartilage cells via the NF-¦ÊB signaling pathway by targeting SOX9. target gene hsa-mir-28 Neuropathic Pain 30058089 miR-28-5p/Zeb1 axis can be a novel therapeutic target for neuropathic pain treatment target gene hsa-mir-485 Lung Neoplasms 30058740 Epigallocatechin-3-gallate inhibited cancer stem cell-like properties by targeting hsa-mir-485-5p/RXR¦Á in lung cancer. target gene hsa-mir-7 Neoplasms [unspecific] 30060955 it suggests that the level of NF90 is increased by a negative feedback loop between NF90 and miR-7 in tumor tissues under physiological conditions target gene hsa-mir-455 "Carcinoma, Bladder" 30061227 dysfunction of the miR-455-TJP1 axis is involved in bladder cancer cell growth and metastasis target gene hsa-mir-342 Nasopharyngeal Neoplasms 30061949 MicroRNA-342 inhibits cell proliferation and invasion in nasopharyngeal carcinoma by directly targeting ZEB1. target gene hsa-mir-95 Osteoarthritis 30063117 Exosomal miR-95-5p regulates chondrogenesis and cartilage degradation via histone deacetylase 2/8. target gene hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 30065618 miR-145 and miR-497 suppress TGF-¦Â-induced epithelial-mesenchymal transition of non-small cell lung cancer by targeting MTDH. target gene hsa-mir-497 "Carcinoma, Lung, Non-Small-Cell" 30065618 miR-145 and miR-497 suppress TGF-¦Â-induced epithelial-mesenchymal transition of non-small cell lung cancer by targeting MTDH. target gene hsa-mir-26a "Carcinoma, Breast" 30066905 A miR-26a/E2F7 feedback loop contributes to tamoxifen resistance in ER-positive breast cancer. target gene hsa-mir-22 Asthma 30068332 "Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmatics." target gene hsa-mir-1258 "Carcinoma, Lung, Non-Small-Cell" 30069987 MicroRNA-1258 suppresses tumour progression via GRB2/Ras/Erk pathway in non-small-cell lung cancer. target gene hsa-mir-340 Colorectal Carcinoma 30070320 MiR-340-5p is a potential prognostic indicator of colorectal cancer and modulates ANXA3. target gene hsa-mir-1269a Colorectal Carcinoma 30070324 MiR-1269a acts as an onco-miRNA in non-small cell lung cancer via down-regulating SOX6. target gene hsa-mir-608 "Adenocarcinoma, Lung" 30070326 MiR-608 exerts tumor suppressive function in lung adenocarcinoma by directly targeting MIF. target gene hsa-mir-122 Glioma 30070328 MiR-122 inhibits cell proliferation and induces apoptosis by targeting runt-related transcription factors 2 in human glioma. target gene hsa-mir-135b Colorectal Carcinoma 30071508 Knockdown of Mir-135b Sensitizes Colorectal Cancer Cells to Oxaliplatin-Induced Apoptosis Through Increase of FOXO1. target gene hsa-mir-543 Esophageal Neoplasms 30071514 "MiR-543 Promotes Migration, Invasion and Epithelial-Mesenchymal Transition of Esophageal Cancer Cells by Targeting Phospholipase A2 Group IVA." target gene hsa-mir-34a Ovarian Neoplasms 30071534 c-Myc re-expression targeting by miR-34a inhibitors protected cells from apoptosis or reversed cisplatin resistance following HDAC1 knockdown or/and cisplatin exposure target gene hsa-let-7a Chronic Obstructive Pulmonary Disease 30072506 "KRAS and EDN1 were identified as key regulators of CMH and were negatively correlated predicted targets of miR-134-5p and let-7a-5p, let-7d-5p, and let-7f-5p" target gene hsa-let-7d Chronic Obstructive Pulmonary Disease 30072506 "KRAS and EDN1 were identified as key regulators of CMH and were negatively correlated predicted targets of miR-134-5p and let-7a-5p, let-7d-5p, and let-7f-5p" target gene hsa-let-7f Chronic Obstructive Pulmonary Disease 30072506 "KRAS and EDN1 were identified as key regulators of CMH and were negatively correlated predicted targets of miR-134-5p and let-7a-5p, let-7d-5p, and let-7f-5p" target gene hsa-mir-134 Chronic Obstructive Pulmonary Disease 30072506 "KRAS and EDN1 were identified as key regulators of CMH and were negatively correlated predicted targets of miR-134-5p and let-7a-5p, let-7d-5p, and let-7f-5p" target gene hsa-mir-31 Hypertrophy 30074205 Atorvastatin Attenuates Myocardial Hypertrophy Induced by Chronic Intermittent Hypoxia In Vitro Partly through miR-31/PKC¦Å Pathway. target gene hsa-mir-31a Hypertrophic Scar 30075370 Inhibition of miR-31a-5p decreases inflammation by down-regulating IL-25 expression in human dermal fibroblast cells (CC-2511 cells) under hyperthermic stress via Wnt/¦Â-catenin pathway. target gene hsa-mir-29c Allergic Asthma 30075787 The role of miR-29c/B7-H3 axis in children with allergic asthma target gene hsa-mir-638 Asthma 30076719 MicroRNA-638 inhibits human airway smooth muscle cell proliferation and migration through targeting cyclin D1 and NOR1. target gene hsa-mir-125a "Carcinoma, Breast" 30076753 MiR-125a-5p functions as a tumour suppressor in breast cancer by downregulating BAP1. target gene hsa-mir-590 "Carcinoma, Breast" 30076901 miR-590-3p inhibits proliferation and promotes apoptosis by targeting activating transcription factor 3 in human breast cancer cells. target gene hsa-mir-224 "Carcinoma, Pancreatic" 30078003 MicroRNA-224 Promotes Pancreatic Cancer Cell Proliferation and Migration by Targeting the TXNIP-Mediated HIF1¦Á Pathway. target gene hsa-mir-27b Kawasaki Syndrome 30078021 miR-27b Suppresses Endothelial Cell Proliferation and Migration by Targeting Smad7 in Kawasaki Disease. target gene hsa-mir-141 Hyperglycemia 30078183 miR-141-3p targets not only protein-coding genes but also the lncRNA H19 target gene hsa-mir-181a Vascular Disease [unspecific] 30080293 FMRP regulates endothelial cell proliferation and angiogenesis via the miR-181a-CaM-CaMKII pathway. target gene hsa-mir-506 Retinoblastoma 30080301 "MiR-506-3p inhibits cell proliferation, induces cell cycle arrest and apoptosis in retinoblastoma by directly targeting NEK6." target gene hsa-mir-29b Asthma 30081328 miR-29b directly targets activation-induced cytidine deaminase in human B cells and can limit its inappropriate expression in na?ve B cells. target gene hsa-mir-301b Melanoma 30081934 Isoliquiritigenin suppresses human melanoma growth by targeting miR-301b/LRIG1 signaling. target gene hsa-mir-125b "Carcinoma, Lung" 30082521 MiR-125b-1-3p Exerts Antitumor Functions in Lung Carcinoma Cells by Targeting S1PR1. target gene hsa-mir-375 "Carcinoma, Renal Cell, Clear-Cell" 30082525 MicroRNA-375 Suppresses the Tumor Aggressive Phenotypes of Clear Cell Renal Cell Carcinomas through Regulating YWHAZ. target gene hsa-mir-218 Parkinson Disease 30083784 "Our results reveal that SLC6A3, TH, and EBF3 targeted by miR-218 could be involved in PD" target gene hsa-mir-191 "Carcinoma, Breast" 30084985 Amplification of Hsa-miR-191/425 Locus Promotes Breast Cancer Proliferation and Metastasis by Targeting DICER1. target gene hsa-mir-425 "Carcinoma, Breast" 30084985 Amplification of Hsa-miR-191/425 Locus Promotes Breast Cancer Proliferation and Metastasis by Targeting DICER1. target gene hsa-mir-133a "Carcinoma, Hepatocellular" 30086463 MiR-133a acts as an anti-oncogene in Hepatocellular carcinoma by inhibiting FOSL2 through TGF-¦Â/Smad3 signaling pathway. target gene hsa-mir-485 Colorectal Carcinoma 30087700 microRNA-485-5p Functions as a Tumor Suppressor in Colorectal Cancer Cells by Targeting CD147. target gene hsa-mir-302c "Carcinoma, Hepatocellular" 30087710 The tumor suppressive miR-302c-3p inhibits migration and invasion of hepatocellular carcinoma cells by targeting TRAF4. target gene hsa-mir-323a Osteosarcoma 30088225 MiR-323a-3p suppressed the glycolysis of osteosarcoma via targeting LDHA. target gene hsa-mir-21 Neoplasms [unspecific] 30092298 MiR-21 regulates the ACAT1 gene in MCF-7 cells. target gene hsa-mir-613 "Carcinoma, Breast, Triple Negative" 30092563 miR-613 directly bound to the 3'-untranslated region (3'-UTR) of WBP2 and regulated the expression of WBP2 target gene hsa-mir-142 "Carcinoma, Hepatocellular" 30092578 lncRNA TUG1-Mediated Mir-142-3p Downregulation Contributes to Metastasis and the Epithelial-to-Mesenchymal Transition of Hepatocellular Carcinoma by Targeting ZEB1. target gene hsa-mir-1292 "Carcinoma, Gastric" 30094096 "MicroRNA-1292-5p inhibits cell growth, migration and invasion of gastric carcinoma by targeting DEK." target gene hsa-mir-942 Liver Fibrosis 30097701 MicroRNA-942 mediates hepatic stellate cell activation by regulating BAMBI expression in human liver fibrosis. target gene hsa-mir-499 Obesity 30097922 MiR-499/PRDM16 axis modulates the adipogenic differentiation of mouse skeletal muscle satellite cells. target gene hsa-mir-143 Melanoma 30098313 MicroRNA-143-3p inhibits growth and invasiveness of melanoma cells by targeting cyclooxygenase-2 and inversely correlates with malignant melanoma progression. target gene hsa-mir-93 "Carcinoma, Cervical" 30098344 Clinical significance and functions of microRNA-93/CDKN1A axis in human cervical cancer. target gene hsa-mir-101 "Carcinoma, Hepatocellular" 30098428 LINC00052/miR-101-3p axis inhibits cell proliferation and metastasis by targeting SOX9 in hepatocellular carcinoma. target gene hsa-mir-101 Glioma 30098431 Long noncoding RNA SNHG12 facilitates the tumorigenesis of glioma through miR-101-3p/FOXP1 axis. target gene hsa-mir-217 "Carcinoma, Bladder" 30098434 Downregulation of circular RNA hsa_circ_0000144 inhibits bladder cancer progression via stimulating miR-217 and suppressing RUNX2 expression. target gene hsa-mir-132 Schizophrenia 30099093 "Moreover, the polycomb-associated H3K27 methyltransferase, EZH1, is regulated by miR-132 and upregulated in the PFC of schizophrenics" target gene hsa-mir-148b Kidney Neoplasms 30099339 MiR-148b-3p inhibits renal carcinoma cell growth and pro-angiogenic phenotype of endothelial cell potentially by modulating FGF2. target gene hsa-mir-758 Glioblastoma 30099442 "Mir-758-5p Suppresses Glioblastoma Proliferation, Migration and Invasion by Targeting ZBTB20." target gene hsa-mir-33a Laryngeal Neoplasms 30102806 Antiproliferative potential of miR-33a in laryngeal cancer Hep-2 cells via targeting PIM1. target gene hsa-mir-34a Lung Neoplasms 30102929 miR-34a negatively regulates the expression of BCL2 and c-MET (genes associated with survival of tumor cells) target gene hsa-mir-23c "Carcinoma, Hepatocellular" 30103114 miR-23c suppresses tumor growth of human hepatocellular carcinoma by attenuating ERBB2IP. target gene hsa-mir-520b Lung Neoplasms 30106218 MiR-520b restrains cell growth by targeting HDAC4 in lung cancer. target gene hsa-mir-498 "Leukemia, Myeloid, Acute" 30107988 Evaluation of the effect of TIM-3 suppression by miR-498 and its effect on apoptosis and proliferation rate of HL-60 cell line. target gene hsa-mir-96 "Carcinoma, Cervical" 30108433 MiR-96 enhances cellular proliferation and tumorigenicity of human cervical carcinoma cells through PTPN9. target gene hsa-mir-1297 "Squamous Cell Carcinoma, Oral" 30108442 microRNA-1297 involves in the progression of oral squamous cell carcinoma through PTEN. target gene hsa-mir-30b Glioma 30108445 MiR-30b-5p modulates glioma cell proliferation by direct targeting MTDH. target gene hsa-mir-582 "Carcinoma, Endometrial" 30108448 Upregulation of miR-582-5p regulates cell proliferation and apoptosis by targeting AKT3 in human endometrial carcinoma. target gene hsa-mir-4728 "Lymphoma, Burkitt" 30108451 MicroRNA-4728 serves as a suppressor and antagonist of oncogenic MAPK in Burkitt lymphoma. target gene hsa-mir-4728 "Carcinoma, Thyroid, Papillary" 30108452 MicroRNA-4728 mediated regulation of MAPK oncogenic signaling in papillary thyroid carcinoma. target gene hsa-mir-204 Kidney Diseases [unspecific] 30110560 MicroRNA-204-5p suppresses IL6-mediated inflammatory response and chemokine generation in HK-2 renal tubular epithelial cells by targeting IL6R. target gene hsa-mir-206 Soft Tissue Sarcoma 30111166 The oncomir face of microRNA-206: A permanent miR-206 transfection study. target gene hsa-mir-34a "Leukemia, Lymphocytic, Chronic, B-Cell" 30111844 MicroRNA miR-34a downregulates FOXP1 during DNA damage response to limit BCR signalling in chronic lymphocytic leukaemia B cells. target gene hsa-mir-153 Gastric Neoplasms 30112020 MicroRNA-153 functions as a tumor suppressor in gastric cancer via targeting Kruppel-like factor 5. target gene hsa-mir-340 Acute Ischemic Stroke 30112629 "Acute stroke induces the downregulation of miR-340-5p, which subsequently upregulates ARG1 protein expression" target gene hsa-mir-369 "Carcinoma, Thyroid, Papillary" 30114378 Downregulation of TSPAN13 by miR-369-3p inhibits cell proliferation in papillary thyroid cancer (PTC). target gene hsa-mir-6852 Colorectal Carcinoma 30116340 miR-6852 serves as a prognostic biomarker in colorectal cancer and inhibits tumor growth and metastasis by targeting TCF7. target gene hsa-mir-379 Nasopharyngeal Neoplasms 30116374 "MicroRNA-379 suppresses cell proliferation, migration and invasion in nasopharyngeal carcinoma by targeting tumor protein D52." target gene hsa-mir-26a Neuropathic Pain 30118880 Effects of miR-26a-5p on neuropathic pain development by targeting MAPK6 in in CCI rat models. target gene hsa-mir-539 "Carcinoma, Lung, Non-Small-Cell" 30119173 miR-539 enhances chemosensitivity to cisplatin in non-small cell lung cancer by targeting DCLK1. target gene hsa-mir-30c Atherosclerosis 30119891 MicroRNA-30c-5p inhibits NLRP3 inflammasome-mediated endothelial cell pyroptosis through FOXO3 down-regulation in atherosclerosis. target gene hsa-mir-30a Hidradenitis Suppurativa 30120935 Nicastrin/miR-30a-3p/RAB31 Axis Regulates Keratinocyte Differentiation by Impairing EGFR Signaling in Familial Acne Inversa. target gene hsa-mir-494 Acute Respiratory Distress Syndrome 30121199 MicroRNA-494 inhibition alleviates acute lung injury through Nrf2 signaling pathway via NQO1 in sepsis-associated acute respiratory distress syndrome. target gene hsa-mir-122 "Carcinoma, Biliary Tract" 30121648 "miR-122-5p Inhibits the Proliferation, Invasion and Growth of Bile Duct Carcinoma Cells by Targeting ALDOA." target gene hsa-mir-486 Myocardial Infarction 30121658 MicroRNA-486 Alleviates Hypoxia-Induced Damage in H9c2 Cells by Targeting NDRG2 to Inactivate JNK/C-Jun and NF-¦ÊB Signaling Pathways. target gene hsa-mir-223 "Lymphoma, Mantle-Cell" 30122018 "The expression of miR-223 was repressed in MCL and was associated with poor clinical outcomes, which may be probably attributed to its direct targeting SOX11" target gene hsa-mir-140 Rheumatoid Arthritis 30123050 "the novel miR-140-3p-FGF9 interaction was validated in different microRNA prediction databases, and proposed to participate in the pathogenesis of joint destruction through dysregulated cell growth in RA" target gene hsa-mir-524 Osteosarcoma 30123092 MicroRNA-524 promotes cell proliferation by down-regulating PTEN expression in osteosarcoma. target gene hsa-mir-151a Visceral Leishmaniasis 30125570 "we identified target gene of differentially expressed miRNAs (target miRNAs: hsa-mir-15b, hsa-mir-671, hsa-mir-151a and has-mir-30c) which was confirmed by real time stem-loop PCR" target gene hsa-mir-15b Visceral Leishmaniasis 30125570 "we identified target gene of differentially expressed miRNAs (target miRNAs: hsa-mir-15b, hsa-mir-671, hsa-mir-151a and has-mir-30c) which was confirmed by real time stem-loop PCR" target gene hsa-mir-30c Visceral Leishmaniasis 30125570 "we identified target gene of differentially expressed miRNAs (target miRNAs: hsa-mir-15b, hsa-mir-671, hsa-mir-151a and has-mir-30c) which was confirmed by real time stem-loop PCR" target gene hsa-mir-671 Visceral Leishmaniasis 30125570 "we identified target gene of differentially expressed miRNAs (target miRNAs: hsa-mir-15b, hsa-mir-671, hsa-mir-151a and has-mir-30c) which was confirmed by real time stem-loop PCR" target gene hsa-mir-150 "Carcinoma, Thyroid, Papillary" 30126001 "MicroRNA-150-5p affects cell proliferation, apoptosis, and EMT by regulation of the BRAFV600E mutation in papillary thyroid cancer cells." target gene hsa-mir-181a "Carcinoma, Breast" 30126376 "Several miRNAs including miR-18a, miR-19a and miR-181a were predicted in silico to target the canine estrogen receptor (ESR1¦Á)" target gene hsa-mir-18a "Carcinoma, Breast" 30126376 "Several miRNAs including miR-18a, miR-19a and miR-181a were predicted in silico to target the canine estrogen receptor (ESR1¦Á)" target gene hsa-mir-19a "Carcinoma, Breast" 30126376 "Several miRNAs including miR-18a, miR-19a and miR-181a were predicted in silico to target the canine estrogen receptor (ESR1¦Á)" target gene hsa-mir-16 Gastric Neoplasms 30127890 miR-16 targets SALL4 to repress the proliferation and migration of gastric cancer. target gene hsa-mir-106b "Carcinoma, Hepatocellular" 30127897 miR-106b targets DAB2 to promote hepatocellular carcinoma cell proliferation and metastasis. target gene hsa-mir-18a Osteosarcoma 30127908 miR-18a-5p promotes cell invasion and migration of osteosarcoma by directly targeting IRF2. target gene hsa-mir-375 Liver Neoplasms 30127930 Upregulation of miR-375 inhibits human liver cancer cell growth by modulating cell proliferation and apoptosis via targeting ErbB2. target gene hsa-mir-2682 Osteosarcoma 30127935 "MicroRNA-2682-3p inhibits osteosarcoma cell proliferation by targeting CCND2, MMP8 and Myd88." target gene hsa-mir-761 Gastric Neoplasms 30127949 microRNA-761 regulates glycogen synthase kinase 3¦Â expression and promotes the proliferation and cell cycle of human gastric cancer cells. target gene hsa-mir-449b "Carcinoma, Lung, Non-Small-Cell" 30128865 Inhibitory Effect of MiR-449b on Cancer Cell Growth and Invasion through LGR4 in Non-Small-Cell Lung Carcinoma. target gene hsa-mir-224 "Carcinoma, Cervical" 30129088 MicroRNA-224 inhibition prevents progression of cervical carcinoma by targeting PTX3. target gene hsa-mir-5582 Neoplasms [unspecific] 30129155 "Hsa-miR-5582-3P regulatory effect on TGF¦Â signaling through targeting of TGF¦Â-R1, TGF¦Â-R2, SMAD3, and SMAD4 transcripts." target gene hsa-mir-766 "Carcinoma, Hepatocellular" 30130435 MicroRNA-766 promotes cancer progression by targeting NR3C2 in hepatocellular carcinoma. target gene hsa-mir-124a Glioma 30131250 "microRNA-124a suppresses PHF19 over-expression, EZH2 hyper-activation, and aberrant cell proliferation in human glioma." target gene hsa-mir-211 Glaucoma 30131252 Intraocular miR-211 exacerbates pressure-induced cell death in retinal ganglion cells via direct repression of FRS2 signaling. target gene hsa-mir-1254 "Carcinoma, Breast" 30132526 MicroRNA-1254 exerts?oncogenic effects by directly targeting RASSF9 in human breast cancer. target gene hsa-mir-424 Hemangioma 30132564 MicroRNA?424 suppresses the proliferation of hemangioma?derived endothelial cells by targeting VEGFR?2. target gene hsa-mir-6089 Rheumatoid Arthritis 30132861 Exosome-encapsulated miR-6089 regulates inflammatory response via targeting TLR4. target gene hsa-mir-26a Ischemia-Reperfusion Injury 30132885 Effect of microRNA-26a on vascular endothelial cell injury caused by lower extremity ischemia-reperfusion injury through the AMPK pathway by targeting PFKFB3. target gene hsa-mir-30e Ovarian Neoplasms 30134224 the expression of YWHAZ was directly down-regulated by miR-30e in resistant ovarian cancer cells target gene hsa-mir-96 Chronic Cerebral Hypoperfusion 30134226 miR-96 may play a key role in autophagy under CCH by regulating mTOR target gene hsa-mir-16 "Squamous Cell Carcinoma, Oral" 30136280 MicroRNA-16 functions as a tumor-suppressor gene in oral squamous cell carcinoma by targeting AKT3 and BCL2L2. target gene hsa-mir-381 "Carcinoma, Bladder" 30138038 Dual regulatory role of CCNA2 in modulating CDK6 and MET-mediated cell-cycle pathway and EMT progression is blocked by miR-381-3p in bladder cancer. target gene hsa-mir-154 "Carcinoma, Renal Cell" 30138594 Oncogene miR-154-5p regulates cellular function and acts as a molecular marker with poor prognosis in renal cell carcinoma. target gene hsa-mir-27a Ovarian Neoplasms 30138596 Integrated microarray meta-analysis identifies miRNA-27a as an oncogene in ovarian cancer by inhibiting FOXO1. target gene hsa-mir-135a Ovarian Neoplasms 30138893 MicroRNA-135a-3p is downregulated and serves as a tumour suppressor in ovarian cancer by targeting CCR2. target gene hsa-mir-454 Preeclampsia 30138897 "MicroRNA-454 is involved in regulating trophoblast cell proliferation, apoptosis, and invasion in preeclampsia by modulating the expression of ephrin receptor B4." target gene hsa-mir-504 "Carcinoma, Hepatocellular" 30142536 MicroRNA-504 functions as a tumor suppressor in hepatocellular carcinoma through inhibiting Frizzled-7-mediated-Wnt/¦Â-catenin signaling. target gene hsa-mir-1258 Colorectal Carcinoma 30144184 Upregulated miR-1258 regulates cell cycle and inhibits cell proliferation by directly targeting E2F8 in CRC. target gene hsa-mir-202 Colorectal Carcinoma 30144500 MicroRNA-202-5p functions as a tumor suppressor in colorectal carcinoma by directly targeting SMARCC1. target gene hsa-mir-383 Cholangiocarcinoma 30145803 "miR-383 promotes cholangiocarcinoma cell proliferation, migration, and invasion through targeting IRF1." target gene hsa-mir-27a Ischemia-Reperfusion Injury 30145824 MiR-27a-5p regulates apoptosis of liver ischemia-reperfusion injury in mice by targeting Bach1. target gene hsa-mir-766 "Carcinoma, Hepatocellular" 30145863 MicroRNA-766-3p Inhibits Tumour Progression by Targeting Wnt3a in Hepatocellular Carcinoma. target gene hsa-mir-495 "Carcinoma, Lung, Non-Small-Cell" 30146342 The miR 495-UBE2C-ABCG2/ERCC1 axis reverses cisplatin resistance by downregulating drug resistance genes in cisplatin-resistant non-small cell lung cancer cells. target gene hsa-mir-133a Asthma 30146725 MicroRNA-133a alleviates airway remodeling in asthtama through PI3K/AKT/mTOR signaling pathway by targeting IGF1R. target gene hsa-mir-126 Acute Kidney Failure 30146769 "Gain-and-loss-of-function studies demonstrated that miRNAs, such as miR-24, miR-126, miR-494, and miR-687, may bind to the 3'-untranslated region of their target genes to regulate inflammation, programmed cell death, and cell cycle in the injury and repair stages of AKI" target gene hsa-mir-24 Acute Kidney Failure 30146769 "Gain-and-loss-of-function studies demonstrated that miRNAs, such as miR-24, miR-126, miR-494, and miR-687, may bind to the 3'-untranslated region of their target genes to regulate inflammation, programmed cell death, and cell cycle in the injury and repair stages of AKI" target gene hsa-mir-494 Acute Kidney Failure 30146769 "Gain-and-loss-of-function studies demonstrated that miRNAs, such as miR-24, miR-126, miR-494, and miR-687, may bind to the 3'-untranslated region of their target genes to regulate inflammation, programmed cell death, and cell cycle in the injury and repair stages of AKI" target gene hsa-mir-687 Acute Kidney Failure 30146769 "Gain-and-loss-of-function studies demonstrated that miRNAs, such as miR-24, miR-126, miR-494, and miR-687, may bind to the 3'-untranslated region of their target genes to regulate inflammation, programmed cell death, and cell cycle in the injury and repair stages of AKI" target gene hsa-mir-181c Machado-Joseph Disease 30147021 MiR-32 and miR-181c effectively targeted the 3¡¯UTR of ATXN3 and suppressed the expression of ATXN3 target gene hsa-mir-32 Machado-Joseph Disease 30147021 MiR-32 and miR-181c effectively targeted the 3¡¯UTR of ATXN3 and suppressed the expression of ATXN3 target gene hsa-mir-495 Gastric Neoplasms 30147110 MicroRNA-495 Confers Increased Sensitivity to Chemotherapeutic Agents in Gastric Cancer via the Mammalian Target of Rapamycin (mTOR) Signaling Pathway by Interacting with Human Epidermal Growth Factor Receptor 2 (ERBB2). target gene hsa-mir-7641 "Carcinoma, Bladder" 30149755 Curcumin Suppresses microRNA-7641-Mediated Regulation of p16 Expression in Bladder Cancer. target gene hsa-mir-451 Osteoporosis 30151091 MicroRNA-451 blockade promotes osteoblastic differentiation and skeletal anabolic effects by promoting YWHAZ-mediated RUNX2 protein stabilization. target gene hsa-mir-27a Peri-Implantitis 30151888 MiR-27a targets DKK2 and SFRP1 to promote reosseointegration in the regenerative treatment of peri-implantitis. target gene hsa-mir-29 "Carcinoma, Renal Cell" 30153702 Genes regulated by the anti-tumor miR-29 family are closely involved in the molecular pathogenesis of renal cell carcinoma target gene hsa-mir-590 Asthma 30154893 MicroRNA-590-5p represses proliferation of human fetal airway smooth muscle cells by targeting signal transducer and activator of transcription 3. target gene hsa-mir-362 Lung Neoplasms 30155491 Aberrant Expression of miR-362 Promotes Lung Cancer Metastasis through Downregulation of Sema3A. target gene hsa-mir-145 "Carcinoma, Breast" 30157476 The Dysregulated Expression of KCNQ1OT1 and Its Interaction with Downstream Factors miR-145/CCNE2 in Breast Cancer Cells. target gene hsa-mir-138 Sepsis 30157481 MicroRNA-138 Aggravates Inflammatory Responses of Macrophages by Targeting SIRT1 and Regulating the NF-¦ÊB and AKT Pathways. target gene hsa-mir-381 "Carcinoma, Cervical" 30161290 miR-381-3p restrains cervical cancer progression by downregulating FGF7. target gene hsa-mir-34a Gastric Neoplasms 30165351 Increased Lactate in Gastric Cancer Tumor-Infiltrating Lymphocytes Is Related to Impaired T Cell Function Due to miR-34a Deregulated Lactate Dehydrogenase A. target gene hsa-mir-718 "Carcinoma, Thyroid, Papillary" 30166214 miR-718 is involved in malignancy of papillary thyroid cancer through repression of PDPK1. target gene hsa-mir-889 Neoplasms [unspecific] 30167605 "Circ008913, via miR-889 regulation of DAB2IP/ZEB1, is involved in the arsenite-induced acquisition of CSC-like properties by human keratinocytes in carcinogenesis." target gene hsa-mir-299 "Carcinoma, Hepatocellular" 30170358 MiR-299-3p functions as a tumor suppressor via targeting Sirtuin 5 in hepatocellular carcinoma. target gene hsa-mir-126 Kaposi Sarcoma 30170375 MicroRNA-126 regulates the phosphatidylinositol-3 kinase (PI3K)/protein kinase B (AKT) pathway in SLK cells in vitro and the expression of its pathway members in Kaposi's sarcoma tissue. target gene hsa-mir-139 Glioma 30170559 Targeting the Notch1 oncogene by miR-139-5p inhibits glioma metastasis and epithelial-mesenchymal transition (EMT). target gene hsa-mir-483 "Carcinoma, Thyroid, Anaplastic" 30171257 "MicroRNA 483-3p targets Pard3 to potentiate TGF-¦Â1-induced cell migration, invasion, and epithelial-mesenchymal transition in anaplastic thyroid cancer cells." target gene hsa-mir-874 Diabetic Nephropathy 30171701 MiR-874 alleviates renal injury and inflammatory response in diabetic nephropathy through targeting toll-like receptor-4. target gene hsa-mir-200c Colorectal Carcinoma 30171714 Anticancer effects of miR-200c in colorectal cancer through BMI1. target gene hsa-mir-200a Kidney Neoplasms 30171729 Decreased miR-200a-3p is a key regulator of renal carcinoma growth and migration by directly targeting CBL. target gene hsa-mir-497 Glioma 30171955 miR-497/Wnt3a/c-jun feedback loop regulates growth and epithelial-to-mesenchymal transition phenotype in glioma cells. target gene hsa-mir-1301 Osteosarcoma 30172867 MicroRNA-1301 inhibits migration and invasion of osteosarcoma cells by targeting BCL9. target gene hsa-mir-29a Spinal Cord Injuries 30173324 Lentivirus-Mediated Overexpression of miR-29a Promotes Axonal Regeneration and Functional Recovery in Experimental Spinal Cord Injury via PI3K/Akt/mTOR Pathway. target gene hsa-mir-483 Colon Neoplasms 30173777 Mir-483 inhibits colon cancer cell proliferation and migration by targeting TRAF1. target gene hsa-mir-205 "Diabetes Mellitus, Type 2" 30174230 "miR-205-5p gain-of-function increases AKT phosphorylation and decreases SHIP2 in primary hepatocytes, resulting in FOXO inhibition" target gene hsa-mir-543 Gastric Neoplasms 30174445 miRNA-543 promotes cell migration and invasion by targeting SPOP in gastric cancer. target gene hsa-mir-1228 Lung Neoplasms 30176158 CircRNA hsa_circ_100395 regulates miR-1228/TCF21 pathway to inhibit lung cancer progression. target gene hsa-mir-575 "Carcinoma, Hepatocellular" 30176933 Long noncoding RNA MIR31HG inhibits hepatocellular carcinoma proliferation and metastasis by sponging microRNA-575 to modulate ST7L expression. target gene hsa-mir-125b "Carcinoma, Breast" 30177391 "miR-125b-5p inhibits breast cancer cell proliferation, migration and invasion by targeting KIAA1522." target gene hsa-mir-214 Osteosarcoma 30178836 MicroRNA-214 functions as an oncogene in human osteosarcoma by targeting TRAF3. target gene hsa-mir-192 Hepatitis B Virus Infection 30180281 Hepatitis B Virus Induces Autophagy to Promote its Replication by the Axis of miR-192-3p-XIAP via NF-¦ÊB Signaling. target gene hsa-mir-451 Glioma 30180756 MiRNA-451 Inhibits Glioma Cell Proliferation and Invasion Through the mTOR/HIF-1¦Á/VEGF Signaling Pathway by Targeting CAB39. target gene hsa-mir-214 Acute Kidney Failure 30180910 miR-214 ameliorates acute kidney injury via targeting DKK3 and activating of Wnt/¦Â-catenin signaling pathway. target gene hsa-mir-1228 Osteosarcoma 30180920 Exosomal miR-1228 from cancer-associated fibroblasts promotes cell migration and invasion of osteosarcoma by directly targeting SCAI. target gene hsa-mir-1179 "Carcinoma, Lung, Non-Small-Cell" 30180955 MicroRNA-1179 suppresses cell growth and invasion by targeting sperm-associated antigen 5-mediated Akt signaling in human non-small cell lung cancer. target gene hsa-mir-876 "Squamous Cell Carcinoma, Head and Neck" 30181714 MiR-876-5p modulates head and neck squamous cell carcinoma metastasis and invasion by targeting vimentin. target gene hsa-mir-320 Ischemia-Reperfusion Injury 30181740 MiR-320 regulates cardiomyocyte apoptosis induced by ischemia-reperfusion injury by targeting AKIP1. target gene hsa-mir-21 "Lymphoma, Hodgkin" 30184526 MiR-21-5p is upregulated in cHL compared to GC-B cells and protects cHL cells from apoptosis possibly via targeting BTG2 and PELI1 target gene hsa-mir-146a "Carcinoma, Renal Cell, Clear-Cell" 30184528 "Hypoxia-Regulated miR-146a Targets Cell Adhesion Molecule 2 to Promote Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma." target gene hsa-mir-137 Hypertrophic Scar 30184530 miR-137 Inhibits Proliferation and Metastasis of Hypertrophic Scar Fibroblasts via Targeting Pleiotrophin. target gene hsa-mir-338 Rheumatoid Arthritis 30184542 "miR-338-5p Regulates the Viability, Proliferation, Apoptosis and Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes by Targeting NFAT5." target gene hsa-mir-1 Prostate Neoplasms 30185212 The putative tumour suppressor miR-1-3p modulates prostate cancer cell aggressiveness by repressing E2F5 and PFTK1. target gene hsa-mir-301a Neoplasms [unspecific] 30185897 Malignant Transformation of Human Bronchial Epithelial Cells Induced by Arsenic through STAT3/miR-301a/SMAD4 Loop. target gene hsa-mir-21 Colorectal Carcinoma 30186399 Gambogic acid regulates the migration and invasion of colorectal cancer via microRNA-21-mediated activation of phosphatase and tensin homolog. target gene hsa-mir-192 "Diabetes Mellitus, Type 1" 30186503 "miR-192 is upregulated in T1DM, regulates pancreatic ¦Â-cell development and inhibits insulin secretion through suppressing GLP-1 expression." target gene hsa-mir-134 Neuropathic Pain 30187947 MiR-134-5p attenuates neuropathic pain progression through targeting Twist1. target gene hsa-mir-210 "Carcinoma, Breast" 30188754 "Up-regulation of miR-210 induced by a hypoxic microenvironment promotes breast cancer stem cells metastasis, proliferation, and self-renewal by targeting E-cadherin." target gene hsa-mir-23b Wound Healing 30188966 miR-23b promotes cutaneous wound healing through inhibition of the inflammatory responses by targeting ASK1. target gene hsa-mir-590 Intracerebral Hemorrhage 30190124 MiR-590-5p alleviates intracerebral hemorrhage-induced brain injury through targeting Peli1 gene expression. target gene hsa-mir-384 Diabetic Retinopathy 30191948 MicroRNA-384-3p inhibits retinal neovascularization through targeting hexokinase 2 in mice with diabetic retinopathy. target gene hsa-mir-125b Ischemia-Reperfusion Injury 30193876 MicroRNA-125b mimic inhibits ischemia reperfusion-induced neuroinflammation and aberrant p53 apoptotic signalling activation through targeting TP53INP1. target gene hsa-mir-324 Osteoarthritis 30193893 miR-324-5p is up regulated in end-stage osteoarthritis and regulates Indian Hedgehog signalling by differing mechanisms in human and mouse. target gene hsa-mir-217 "Leukemia, Myeloid, Chronic" 30195077 miR-217 sensitizes chronic myelogenous leukemia cells to tyrosine kinase inhibitors by targeting pro-oncogenic anterior gradient 2. target gene hsa-mir-98 Coronary Artery Disease 30195495 MicroRNA-98 regulates hepatic cholesterol metabolism via targeting sterol regulatory element-binding protein 2. target gene hsa-mir-429 "Leukemia, Lymphoblastic, Acute, T-Cell" 30195757 A regulatory loop miR-429-MYCN-MFHAS1 was found potentially associated with the remission of T-ALL target gene hsa-mir-663a Male Infertility 30195770 "miR-663a has been identified as the first microRNA that promotes the proliferation and DNA synthesis and suppresses the early apoptosis of human SSCs by targeting NFIX via cell cycle regulators Cyclin A2, Cyclin B1, and Cyclin E1" target gene hsa-mir-327 Ischemia-Reperfusion Injury 30196287 Down-Regulation of miR-327 Alleviates Ischemia/Reperfusion-Induced Myocardial Damage by Targeting RP105. target gene hsa-mir-423 Ischemia-Reperfusion Injury 30202848 "CFs participate in cardioprotective effects via an exosomes/microvesicles pathway during the acute phase of ischemia-reperfusion injury and Postcon can enhance this effect by upregulating the expression of CFs exosomes/microvesicles miR-423-3p, which targets the downstream effector RAP2C" target gene hsa-mir-7 Lung Fibrosis 30202956 The CDR1as/miR-7/TGFBR2 axis modulates EMT in silica-induced pulmonary fibrosis. target gene hsa-mir-182 "Squamous Cell Carcinoma, Oral" 30205384 miR-182-5p Promotes Growth in Oral Squamous Cell Carcinoma by Inhibiting CAMK2N1. target gene hsa-mir-150 "Carcinoma, Hepatocellular" 30205391 "Long Non-Coding RNA PVT1/miR-150/ HIG2 Axis Regulates the Proliferation, Invasion and the Balance of Iron Metabolism of Hepatocellular Carcinoma." target gene hsa-mir-214 "Carcinoma, Hepatocellular" 30206974 miR-214-5p targets KLF5 and suppresses proliferation of human hepatocellular carcinoma cells. target gene hsa-mir-146b "Carcinoma, Renal Cell" 30206978 Inhibition of miR146b-5p suppresses CT-guided renal cell carcinoma by targeting TRAF6. target gene hsa-mir-200c "Carcinoma, Breast" 30209363 Phosphodiesterase 7B/microRNA-200c relationship regulates triple-negative breast cancer cell growth. target gene hsa-mir-451a "Carcinoma, Basal Cell" 30209892 miRNA-451a/TBX1 axis played a pivotal role in BCC tumorigenesis target gene hsa-mir-298 Epilepsy 30210283 MicroRNA-298 Reverses Multidrug Resistance to Antiepileptic Drugs by Suppressing MDR1/P-gp Expression in vitro. target gene hsa-mir-218 "Carcinoma, Cervical" 30210595 miRNA-218 regulates the proliferation and apoptosis of cervical cancer cells via targeting Gli3. target gene hsa-mir-124 "Carcinoma, Hepatocellular" 30210622 Identification of microRNA-124 in regulation of Hepatocellular carcinoma through BIRC3 and the NF-¦ÊB pathway. target gene hsa-mir-7702 Colorectal Carcinoma 30210694 Species-specific function of microRNA-7702 in human colorectal cancer cells via targeting TADA1. target gene hsa-mir-506 "Carcinoma, Hepatocellular" 30210926 MicroRNA-506 suppresses invasiveness and metastasis of human hepatocellular carcinoma cells by targeting IL8. target gene hsa-mir-21 Colon Neoplasms 30212824 "The CircRNA-ACAP2/Hsa-miR-21-5p/ Tiam1 Regulatory Feedback Circuit Affects the Proliferation, Migration, and Invasion of Colon Cancer SW480 Cells." target gene hsa-mir-21 Renal Fibrosis 30212825 Total Flavonoids from Leaves of Carya Cathayensis Ameliorate Renal Fibrosis via the miR-21/Smad7 Signaling Pathway. target gene hsa-mir-33b Osteosarcoma 30213286 MiR-33b inhibits osteosarcoma cell proliferation through suppression of glycolysis by targeting Lactate Dehydrogenase A (LDHA). target gene hsa-mir-637 Melanoma 30213289 MiR-637 suppresses melanoma progression through directly targeting P-REX2a and inhibiting PTEN/AKT signaling pathway. target gene hsa-mir-124 "Carcinoma, Bladder" 30214503 "MicroRNA-124 inhibits cell proliferation, invasion and migration by targeting CAV1 in bladder cancer." target gene hsa-mir-6852 Gastric Neoplasms 30214548 MicroRNA-6852 suppresses cell proliferation and invasion via targeting forkhead box J1 in gastric cancer. target gene hsa-mir-199a Ovarian Neoplasms 30214589 miRNA-199a-5p suppresses proliferation and invasion by directly targeting NF-¦ÊB1 in human ovarian cancer cells. target gene hsa-mir-1265 Ovarian Neoplasms 30214617 Identifying miRNA-mRNA regulation network of major depressive disorder in ovarian cancer patients. target gene hsa-mir-23b Ovarian Neoplasms 30214617 Identifying miRNA-mRNA regulation network of major depressive disorder in ovarian cancer patients. target gene hsa-mir-33b Ovarian Neoplasms 30214617 Identifying miRNA-mRNA regulation network of major depressive disorder in ovarian cancer patients. target gene hsa-mir-629 Ovarian Neoplasms 30214617 Identifying miRNA-mRNA regulation network of major depressive disorder in ovarian cancer patients. target gene hsa-mir-933 Ovarian Neoplasms 30214617 Identifying miRNA-mRNA regulation network of major depressive disorder in ovarian cancer patients. target gene hsa-mir-346 "Carcinoma, Hepatocellular" 30216442 LncRNA DGCR5 represses the development of hepatocellular carcinoma by targeting the miR-346/KLF14 axis. target gene hsa-mir-409 "Carcinoma, Renal Cell, Clear-Cell" 30218446 Phosphoinositide-dependent kinase 1-associated glycolysis is regulated by miR-409-3p in clear cell renal cell carcinoma. target gene hsa-mir-1306 "Carcinoma, Hepatocellular" 30219228 miR-1306-3p targets FBXL5 to promote metastasis of hepatocellular carcinoma through suppressing snail degradation. target gene hsa-mir-34a Parkinson Disease 30221494 miR-34a/BCL-2 signaling axis contributes to apoptosis in MPP+ -induced SH-SY5Y cells. target gene hsa-mir-501 Glioma 30221699 miR?501?3p sensitizes glioma cells to cisplatin by targeting MYCN. target gene hsa-mir-184 Nasopharyngeal Neoplasms 30223264 "miR-184 Inhibits Tumor Invasion, Migration and Metastasis in Nasopharyngeal Carcinoma by Targeting Notch2." target gene hsa-mir-146a Sepsis 30224945 miR-146a Attenuates Sepsis-Induced Myocardial Dysfunction by Suppressing IRAK1 and TRAF6 via Targeting ErbB4 Expression. target gene hsa-mir-338 Glioma 30225541 MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1. target gene hsa-mir-23a Atherosclerosis 30227118 MicroRNA-23a-5p promotes atherosclerotic plaque progression and vulnerability by repressing ATP-binding cassette transporter A1/G1 in macrophages. target gene hsa-mir-4317 "Carcinoma, Lung, Non-Small-Cell" 30227870 miR-4317 suppresses non-small cell lung cancer (NSCLC) by targeting fibroblast growth factor 9 (FGF9) and cyclin D2 (CCND2). target gene hsa-mir-204 "Carcinoma, Breast, Triple Negative" 30228364 Molecular pathogenesis of triple-negative breast cancer based on microRNA expression signatures: antitumor miR-204-5p targets AP1S3. target gene hsa-mir-363 "Carcinoma, Renal Cell" 30229899 "MicroRNA-363 inhibits angiogenesis, proliferation, invasion, and migration of renal cell carcinoma via inactivation of the Janus tyrosine kinases 2-signal transducers and activators of transcription 3 axis by suppressing growth hormone receptor gene." target gene hsa-let-7e Multiple Myeloma 30230597 "The miR-125a-3p, miR-125a-5p, miR-99b-5p, and let-7e were powerful miRNAs correlating with the FGFR3, MAP1B, MYRIP, and CDC42BPA under the relevance analysis in the subnetwork." target gene hsa-mir-125a Multiple Myeloma 30230597 "The miR-125a-3p, miR-125a-5p, miR-99b-5p, and let-7e were powerful miRNAs correlating with the FGFR3, MAP1B, MYRIP, and CDC42BPA under the relevance analysis in the subnetwork." target gene hsa-mir-99b Multiple Myeloma 30230597 "The miR-125a-3p, miR-125a-5p, miR-99b-5p, and let-7e were powerful miRNAs correlating with the FGFR3, MAP1B, MYRIP, and CDC42BPA under the relevance analysis in the subnetwork." target gene hsa-mir-143 Heart Failure 30230713 "miR-143 (P? T might contribute to the increased risk and poor prognosis of NSCLC, highlighting the importance of rs767649 in the prevention and therapy of NSCLC." therapeutic target hsa-mir-145 Bladder Neoplasms 26544536 "Taken together, our results identified that lncRNA-UCA1 enhances bladder cancer cell migration and invasion in part through the hsa-miR-145/ZEB1/2/FSCN1 pathway. Therefore, lncRNA-UCA1 might act as a promising therapeutic target for the invasion and metastasis of bladder cancer." therapeutic target hsa-mir-137 Gastric Neoplasms 26545111 "In conclusion, the results reinforced the critical role for the down-regulated miR-137 expression in gastric cancer and suggested that miR-137 expression could be a prognostic indicator for this disease. In addition, these patients with TNM stage III gastric cancer and low miR-137 expression might need more aggressive postoperative treatment and closer follow-up." therapeutic target hsa-mir-362 "Leukemia, Myelogenous, Chronic, BCR-ABL Positive" 26545365 "miR-362-5p acts as an oncomiR that down-regulates GADD45¦Á, which consequently activates the JNK1/2 and P38 signalling. This finding provides novel insights into CML leukaemogenesis and may help identify new diagnostic and therapeutic targets." therapeutic target hsa-mir-134 Atherosclerosis 26546816 "Collectively, our findings indicate that miR-134 may regulate lipid accumulation and proinfiammatory cytokine secretion in macrophages by targeting the ANGPTL4 gene. Our results have also suggested a promising and potential therapeutic target for atherosclerosis." therapeutic target hsa-mir-9 "Carcinoma, Hepatocellular" 26547929 "Our study suggests that miR-9 functions as a tumor suppressor in HCC progression by inhibiting a series of target genes, including the newly validated miR-9/IGF2BP1/AKT&ERK axis, thus providing potential therapeutic targets and novel prognostic biomarkers for HCC patients." therapeutic target hsa-mir-326 "Carcinoma, Lung, Non-Small-Cell" 26548724 "Our study demonstrated a direct target relationship between NSBP1 and miR-326 through which miR-326 inhibited cell proliferation and invasion of NSCLC cells. Thus, miR-326-NSBP1 is a promising candidate target for developing novel anticancer therapeutics for NSCLC." therapeutic target hsa-mir-296 "Carcinoma, Lung, Non-Small-Cell" 26549165 "Taken together, the present study indicated that miR-296-5p regulated PLK1 expression and could function as a tumor suppressor in NSCLC progression, which provides a potential target for gene therapy of NSCLC." therapeutic target hsa-mir-146b Osteosarcoma 26549292 "These results indicated that miR-146b-5p promoted proliferation, migration and invasiveness. It also increased resistance to chemotherapy through the regulation of ZNRF3, and suggested novel potential therapeutic targets for the treatment of osteosarcoma." therapeutic target hsa-mir-885 Neoplasms [unspecific] 26554827 Our work shows how DNp73 promotes cancer stem-like features and provides a mechanistic rationale to target the DNp73-IGF1R cascade as a therapeutic strategy to eradicate CSC. therapeutic target hsa-mir-506 Glioma 26554866 "These results showed that miR-506 functions as a tumor suppressor in glioma by targeting STAT3, suggesting that miR-506 may serve as a potential target in the treatment of human glioma." therapeutic target hsa-mir-143 "Adenocarcinoma, Pancreatic Ductal" 26554910 "miRNA expression profiles should be investigated to evaluate the potential function as biomarkers for early diagnosis, disease progression, response to therapy, and prognosis because of their characteristics of high stability, tissue specificity and ease of availability." therapeutic target hsa-mir-145 "Adenocarcinoma, Pancreatic Ductal" 26554910 "miRNA expression profiles should be investigated to evaluate the potential function as biomarkers for early diagnosis, disease progression, response to therapy, and prognosis because of their characteristics of high stability, tissue specificity and ease of availability." therapeutic target hsa-mir-96 "Adenocarcinoma, Pancreatic Ductal" 26554910 "miRNA expression profiles should be investigated to evaluate the potential function as biomarkers for early diagnosis, disease progression, response to therapy, and prognosis because of their characteristics of high stability, tissue specificity and ease of availability." therapeutic target hsa-mir-320a Osteoporosis 26555194 "We identified two osteoblast miRNAs over-expressed in osteoporotic fractures, which opens novel prospects for research and therapy." therapeutic target hsa-mir-483 Osteoporosis 26555194 "We identified two osteoblast miRNAs over-expressed in osteoporotic fractures, which opens novel prospects for research and therapy." therapeutic target hsa-mir-101 "Squamous Cell Carcinoma, Esophageal" 26556718 "Overexpression of miR-101 in ESCC inhibits proliferation and metastasis. Therefore, the miR-101/COX-2 pathway might be a therapeutic target in ESCC." therapeutic target hsa-mir-543 Hypertension 26562529 "In summary, our study suggested that the downregulation of the miR-543 could alleviate the insulin resistance via the modulation of the SIRT1 expression, which might be a potential new strategy for treating insulin resistance and a promising therapeutic method for hypertension." therapeutic target hsa-mir-182 Breast Neoplasms 26563369 downregulation of miR-182 might find therapeutical value for overcoming trastuzumab resistance. therapeutic target hsa-mir-3175 Neoplasms [unspecific] 26565624 "Our results suggest that HOXB1 functions as a tumor suppressor, regulated by miR-3175 in glioma. These results clarify the pathogenesis of glioma and offer a potential target for its treatment." therapeutic target hsa-mir-186 "Squamous Cell Carcinoma, Esophageal" 26568291 "Our findings established that the miR-186 has a suppressive role in ESCC progression via SKP2-mediated pathway, and this implies that miR-186 could be a potential therapeutic target for ESCC." therapeutic target hsa-mir-224 Cholangiocarcinoma 26573191 IL-6 may promote the invasive and metastatic properties of CCA through upregulated miR-224. Studies of the differentially expressed serum miRNAs in CCA may help to further elucidate the pathogenic processes of this disease and aid in the development of a novel and effective therapeutic strategy. therapeutic target hsa-mir-1246 Colorectal Carcinoma 26573378 "Consequently, these findings provided a molecular basis for the role of miR-1246/CCNG2 in the progression of human CRC and suggested a novel target for the treatment of CRC." therapeutic target hsa-mir-340 Breast Neoplasms 26573744 "In brief, miR-340 plays an important role in breast cancer progression. Thus, miR-340 may be further explored as a novel biomarker for breast cancer metastasis and prognosis,and potentially a therapeutic target." therapeutic target hsa-mir-124 Prostate Neoplasms 26573802 "Taken together, our results offer a preclinical rationale to evaluate miR-124 for cancer treatment." therapeutic target hsa-mir-27b Gastric Neoplasms 26576539 These results show that miR-27b-3p suppresses ROR1 expression through the binding site in the 3'UTR inhibiting the cell proliferation. These findings indicate that miR-27b-3p exerts tumor-suppressive effects in GC through the suppression of oncogene ROR1 expression and suggest a therapeutic application of miR-27b-3p in GC. therapeutic target hsa-mir-449a Gastric Neoplasms 26576674 "Our results demonstrated that miR-449a suppressed Flot2 expression results in decreased cell invasion through repressing TGF-¦Â-mediated-EMT, and provides a new theoretical basis to further investigate miR-449a-regulated Flot2 as a potential biomarker and a promising approach for GC treatment." therapeutic target hsa-mir-634 Ovarian Neoplasms 26576679 miR-634 levels determine chemosensitivity in ovarian cancer cells. We identify miR-634 as a therapeutic candidate to resensitize chemotherapy resistant ovarian tumors. therapeutic target hsa-mir-34a Neoplasms [unspecific] 26580663 microRNA-34a as a Therapeutic Agent against Human Cancer. therapeutic target hsa-mir-1274a Breast Neoplasms 26581147 "Biomarkers of DNA repair and cell cycle control can identify patients at high risk of treatment failure in those receiving radiation therapy for early breast cancer in independent cohorts. These should be further investigated prospectively, especially TOP2A and SKP2, for which targeted therapies are available." therapeutic target hsa-mir-139 Breast Neoplasms 26581147 "Biomarkers of DNA repair and cell cycle control can identify patients at high risk of treatment failure in those receiving radiation therapy for early breast cancer in independent cohorts. These should be further investigated prospectively, especially TOP2A and SKP2, for which targeted therapies are available." therapeutic target hsa-mir-148a "Carcinoma, Lung, Non-Small-Cell" 26584284 Evidence from this study demonstrated that miR-148a exerts tumor-suppressive effects in NSCLC and suggests a new therapeutic option for NSCLC. therapeutic target hsa-mir-203 Osteosarcoma 26584294 "Taken together, these findings suggest that miR-203 acts as a tumor suppressor via regulation of TBK1 expression in OS progression, and miR-203 may be a promising therapeutic target for OS." therapeutic target hsa-mir-4792 "Carcinoma, Nasopharyngeal" 26585487 "These findings suggest that miR-4792 functions as a tumor suppressor in NPC development and progression by targeting FOXC1, which could act as a novel potential therapeutic target for NPC treatment,and miR-4792/FOXC1 pathway that we studied might be used for NPC treatment in future." therapeutic target hsa-mir-125b Endomyocardial Fibrosis 26585673 "In conclusion, miR-125b is critical for induction of cardiac fibrosis and acts as a potent repressor of multiple anti-fibrotic mechanisms.Inhibition of miR-125b may represent a novel therapeutic approach for the treatment of human cardiac fibrosis and other fibrotic diseases." therapeutic target hsa-mir-143 Lung Neoplasms 26586766 "This study shows that miR-143/145 expressed from the tumor microenvironment stimulates neoangiogenesis and supports tumor expansion in the lung, demonstrating a surprising role for the putative tumor suppressor miRNA cluster in promoting tumorigenesis. We propose inhibition of miR-143/145 as a therapeutic avenue to modulate tumor neoangiogenesis." therapeutic target hsa-mir-145 Lung Neoplasms 26586766 "This study shows that miR-143/145 expressed from the tumor microenvironment stimulates neoangiogenesis and supports tumor expansion in the lung, demonstrating a surprising role for the putative tumor suppressor miRNA cluster in promoting tumorigenesis. We propose inhibition of miR-143/145 as a therapeutic avenue to modulate tumor neoangiogenesis." therapeutic target hsa-mir-155 Pneumonia 26589478 Our findings suggest that antagonizing certain microRNA might serve as a potential therapeutic strategy against secondary bacterial infection. therapeutic target hsa-mir-27a Breast Neoplasms 26592661 Our findings provide a novel anti-tumor mechanism of ATO involved in miR-27a for the treatment of breast cancer. therapeutic target hsa-mir-9 "Carcinoma, Lung, Non-Small-Cell" 26593208 "These findings suggest that oncogenic miR-9 targeted FoxO1 to promote cell growth, and downregulation of this axis was involved in erlotinib's growth inhibitory effects. Clarifying the regulation of miRNAs by erlotinib may indicate novel strategies for enhancing EGFR-targeted cancer therapy." therapeutic target hsa-mir-148a "Carcinoma, Hepatocellular" 26599259 miR-148a is an inhibitor of the I¦ÊB kinase alpha/NUMB/NOTCH pathway and an inducer of hepatocytic differentiation that when deregulated promotes HCC initiation and progression. Differentiation-targeted therapy may be a promising strategy to treat and prevent HCC. therapeutic target hsa-mir-184 Ovarian Neoplasms 26601424 "Altogether, our results suggest that miR-184 together with pathologic diagnosis is critical for prognosis determination in EOC patients and help select treatment strategy." therapeutic target hsa-mir-100 "Adenocarcinoma, Pancreatic Ductal" 26606261 "Consistent miR expression profiles, in part regulated by mutant TP53 gene, were identified in gemcitabine-resistant PDAC with significant MRP-1 and Bcl-2 overexpression. These results provide a basis for further elucidation of chemoresistance mechanisms and therapeutic approaches to overcome chemoresistance in PDAC." therapeutic target hsa-mir-125b "Adenocarcinoma, Pancreatic Ductal" 26606261 "Consistent miR expression profiles, in part regulated by mutant TP53 gene, were identified in gemcitabine-resistant PDAC with significant MRP-1 and Bcl-2 overexpression. These results provide a basis for further elucidation of chemoresistance mechanisms and therapeutic approaches to overcome chemoresistance in PDAC." therapeutic target hsa-mir-138 "Adenocarcinoma, Pancreatic Ductal" 26606261 "Consistent miR expression profiles, in part regulated by mutant TP53 gene, were identified in gemcitabine-resistant PDAC with significant MRP-1 and Bcl-2 overexpression. These results provide a basis for further elucidation of chemoresistance mechanisms and therapeutic approaches to overcome chemoresistance in PDAC." therapeutic target hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 26606261 "Consistent miR expression profiles, in part regulated by mutant TP53 gene, were identified in gemcitabine-resistant PDAC with significant MRP-1 and Bcl-2 overexpression. These results provide a basis for further elucidation of chemoresistance mechanisms and therapeutic approaches to overcome chemoresistance in PDAC." therapeutic target hsa-mir-210 "Adenocarcinoma, Pancreatic Ductal" 26606261 "Consistent miR expression profiles, in part regulated by mutant TP53 gene, were identified in gemcitabine-resistant PDAC with significant MRP-1 and Bcl-2 overexpression. These results provide a basis for further elucidation of chemoresistance mechanisms and therapeutic approaches to overcome chemoresistance in PDAC." therapeutic target hsa-mir-31 "Adenocarcinoma, Pancreatic Ductal" 26606261 "Consistent miR expression profiles, in part regulated by mutant TP53 gene, were identified in gemcitabine-resistant PDAC with significant MRP-1 and Bcl-2 overexpression. These results provide a basis for further elucidation of chemoresistance mechanisms and therapeutic approaches to overcome chemoresistance in PDAC." therapeutic target hsa-mir-330 "Adenocarcinoma, Pancreatic Ductal" 26606261 "Consistent miR expression profiles, in part regulated by mutant TP53 gene, were identified in gemcitabine-resistant PDAC with significant MRP-1 and Bcl-2 overexpression. These results provide a basis for further elucidation of chemoresistance mechanisms and therapeutic approaches to overcome chemoresistance in PDAC." therapeutic target hsa-mir-378 "Adenocarcinoma, Pancreatic Ductal" 26606261 "Consistent miR expression profiles, in part regulated by mutant TP53 gene, were identified in gemcitabine-resistant PDAC with significant MRP-1 and Bcl-2 overexpression. These results provide a basis for further elucidation of chemoresistance mechanisms and therapeutic approaches to overcome chemoresistance in PDAC." therapeutic target hsa-mir-99a "Adenocarcinoma, Pancreatic Ductal" 26606261 "Consistent miR expression profiles, in part regulated by mutant TP53 gene, were identified in gemcitabine-resistant PDAC with significant MRP-1 and Bcl-2 overexpression. These results provide a basis for further elucidation of chemoresistance mechanisms and therapeutic approaches to overcome chemoresistance in PDAC." therapeutic target hsa-mir-140 Osteoarthritis 26608362 miR-29a and miR-140 combination treatment may be a possible treatment for OA therapeutic target hsa-mir-22 Gastric Neoplasms 26610210 These findings provide a better understanding of the development and progression of GC and may be an important implication for future therapy of the GC. therapeutic target hsa-mir-543 Gastric Neoplasms 26612257 "Our results identify a new regulatory mechanism of miR-543 on SIRT1 expression in gastric cancer, and raise the possibility that the miR-543/SIRT1 pathway may serve as a potential target for the treatment of gastric cancer." therapeutic target hsa-mir-20b "Carcinoma, Hepatocellular" 26612965 "The whole study suggests that miR-20b, HIF-1¦Á, and VEGF serve as a potential therapeutic agent for hepatocellular carcinoma." therapeutic target hsa-mir-142 Peritoneal Fibrosis 26616819 These results suggest that several miRNAs are involved in PF and that they may be useful as novel diagnostic biomarkers and therapeutic targets for PF. therapeutic target hsa-mir-21 Peritoneal Fibrosis 26616819 These results suggest that several miRNAs are involved in PF and that they may be useful as novel diagnostic biomarkers and therapeutic targets for PF. therapeutic target hsa-mir-221 Peritoneal Fibrosis 26616819 These results suggest that several miRNAs are involved in PF and that they may be useful as novel diagnostic biomarkers and therapeutic targets for PF. therapeutic target hsa-mir-223 Peritoneal Fibrosis 26616819 These results suggest that several miRNAs are involved in PF and that they may be useful as novel diagnostic biomarkers and therapeutic targets for PF. therapeutic target hsa-mir-34a Peritoneal Fibrosis 26616819 These results suggest that several miRNAs are involved in PF and that they may be useful as novel diagnostic biomarkers and therapeutic targets for PF. therapeutic target hsa-mir-96 "Carcinoma, Thyroid, Papillary" 26617698 "The data from the present study demonstrated that miR-96 can promote proliferation, and inhibit apoptosis in PTC cell lines K1 and TPC1, thus miR-96 may play an oncogenic role in PTC by inhibiting the FOXO1 and regulating AKT/FOXO1/Bim pathway, and it may serve as a novel therapeutic target for miRNA-based PTC therapy." therapeutic target hsa-mir-200a "Carcinoma, Hepatocellular" 26617701 "Our study reveals an important role of miR-200a in inhibiting EMT,proliferation and migration in HCC cells, suggesting the possibility of miR-200a-based therapeutics in HCC." therapeutic target hsa-mir-299 Lung Neoplasms 26617714 "Therefore, the disordered decreased of miR-299-3p and resulting ABCE1 up-expression may contribute to chemoresistance of lung cancer, and miR-299-3p-ABCE1 may represent a new potential therapeutic target for the treatment of chemoresistance of lung cancer." therapeutic target hsa-mir-101 "Carcinoma, Cervical" 26617722 "MiR-101 likely acts as a tumor suppressor in cervical cancer.Overexpression of miR-101 decreased expression of its target gene Cox-2 and inhibited proliferation and invasion, and promoted apoptosis to suppress tumorigenicity. MiR-101 is a promising new target for the development of therapeutic strategies for the clinical treatment of cervical cancer." therapeutic target hsa-mir-126 Glioma 26617742 "Taken together, these findings showed that miR-126 functions as a tumor suppressor in glioma cells by targeting IRS-1 expression via the PI3K/AKT signaling pathways, suggesting that miR-126 might be a novel target for therapeutic strategies in glioma." therapeutic target hsa-mir-10b "Carcinoma, Renal Cell, Clear-Cell" 26617769 Our results suggest that miR-10b plays a tumor-suppressive role in ccRCC. Demethylation of miR-10b may be therapeutically beneficial for ccRCC treatment. therapeutic target hsa-mir-374a Osteosarcoma 26617789 "Our study suggested that miR-374a functions as an oncogene in OS, and the miR-374a/Axin2 axis might represent a potential therapeutic target for OS intervention." therapeutic target hsa-mir-142 "Carcinoma, Lung, Non-Small-Cell" 26617792 These results suggest that miR-142-3p may be a tumor suppressor through the downregulation of HMGB1 in NSCLC. miR-142-3p may be a tumor suppressor and a potential therapeutic agent for patients with NSCLC. therapeutic target hsa-mir-137 "Carcinoma, Lung, Non-Small-Cell" 26617798 "Taken together, our findings suggested that miR-137/BMP7 axis could contribute to the progression of NSCLC, suggesting miR-137 as a potential therapeutic target for the treatment of NSCLC." therapeutic target hsa-mir-338 Gastric Neoplasms 26617808 "Our study suggested that miR-338-3p is significantly decreased in gastric cancer, and inhibits cell proliferation, migration and invasion partially via the downregulation of ADAM17. Thus, miR-338-3p may represent a potential therapeutic target for gastric cancer intervention." therapeutic target hsa-mir-185 "Carcinoma, Lung, Non-Small-Cell" 26617940 "Collectively, we conclude that miR-185 has a critical function by blocking AKT1 in NSCLC cells, and it may be a novel therapeutic agent for miRNA based NSCLC therapy." therapeutic target hsa-mir-140 Glioma 26619802 "Taken together, we have demonstrated the fact that knockdown of MALAT1 resulted in the increased permeability of BTB, which might contribute to establishing potential therapeutic strategies for human gliomas." therapeutic target hsa-mir-34a Multiple Myeloma 26620594 Delivery of miR-34a by chitosan/PLGA nanoplexes for the anticancer treatment of multiple myeloma. therapeutic target hsa-mir-152 Gastric Neoplasms 26627200 "TGF-¦Â could induce HLA-G expression in GC by inhibiting miR-152,involving its negative regulation on HLA-G. Since TGF-¦Â induced HLA-G up-regulation plays important role in immune escape, a potential application of miR-152 was suggested in GC treatment, or miR-152 might be one potential biomarker for GC." therapeutic target hsa-mir-17 "Carcinoma, Breast, Triple Negative" 26629823 "Our results imply that therapeutic antisense sequences against miRNAs should be designed to target the miRNA strand with the greatest number of putative binding sites in the target mRNAs, while minimizing affinity for the minor strand." therapeutic target hsa-mir-133a Gastric Neoplasms 26629938 These outcomes might be secondary to the increased expression of miR-133a after the treatment with UA. therapeutic target hsa-mir-15a Melanoma 26631117 Our results support a key role of IL-10R¦Á in the development and progression of melanoma and suggest that the IL-10/IL-10 receptor system may become a new therapeutic target for melanoma treatment. therapeutic target hsa-mir-185 Melanoma 26631117 Our results support a key role of IL-10R¦Á in the development and progression of melanoma and suggest that the IL-10/IL-10 receptor system may become a new therapeutic target for melanoma treatment. therapeutic target hsa-mir-211 Melanoma 26631117 Our results support a key role of IL-10R¦Á in the development and progression of melanoma and suggest that the IL-10/IL-10 receptor system may become a new therapeutic target for melanoma treatment. therapeutic target hsa-mir-409 Breast Neoplasms 26631969 "Our data collectively indicate that miR-409-3p functions as a tumor suppressor in BC through downregulating Akt1, supporting the targeting of the novel miR-409-3p/Akt1 axis as a potentially effective therapeutic approach for BC." therapeutic target hsa-mir-145 Prostate Neoplasms 26632856 This novel study shows a role for miR-145 in modulating radiosensitivity in vivo and highlights the need for further study investigating the potential role of miR-145 as both a predictive marker of response and a novel therapeutic agent with which to enhance the efficacy of radiation therapy. therapeutic target hsa-mir-324 Cardiovascular Diseases [unspecific] 26633713 "Our study defines the NFAT4/ miR-324-5p/Mtfr1 axis, which participates in the regulation of mitochondrial fission and cardiomyocyte apoptosis, and suggests potential new treatment avenues for cardiac diseases." therapeutic target hsa-mir-122 Liver Diseases [unspecific] 26636761 "Taken together, our study indicates that miR-122 may downregulate cytokine production in HSCs and macrophage chemotaxis and that the targeting of miR-122 may have therapeutic potential for preventing the progression of liver diseases." therapeutic target hsa-mir-424 "Carcinoma, Endometrial" 26638889 "Taken together, our study suggests that increased miR-424 suppresses E2-induced cell growth, and providing a potential therapeutic target for estrogen-associated endometrial carcinoma." therapeutic target hsa-mir-134 Lung Neoplasms 26642897 "Altogether, our data demonstrated an altered expression of two development-related miRNAs namely miR-134 and miR-187 in lung tumors for the first time. Moreover we have shown that miR-134 and miR-187 expression alternation were in accordance with their approved regulatory roles, therefore these miRNAs could serve as new biomarkers with potential usefulness in lung cancer diagnosis and treatments. In addition, miR-187 expression in tumor cells could perturb cell cycle which supported its possible role as tumor suppressor." therapeutic target hsa-mir-187 Lung Neoplasms 26642897 "Altogether, our data demonstrated an altered expression of two development-related miRNAs namely miR-134 and miR-187 in lung tumors for the first time. Moreover we have shown that miR-134 and miR-187 expression alternation were in accordance with their approved regulatory roles, therefore these miRNAs could serve as new biomarkers with potential usefulness in lung cancer diagnosis and treatments. In addition, miR-187 expression in tumor cells could perturb cell cycle which supported its possible role as tumor suppressor." therapeutic target hsa-mir-150 "Leukemia, Myeloid" 26644403 "Our findings indicate that decreased KLF4 expression mediates antileukemic effects through regulation of gene and microRNA networks,containing miR-150, CDKN1A, and MYC, and provide mechanistic support for therapeutic strategies increasing KLF4 expression." therapeutic target hsa-mir-33a Atherosclerosis 26645139 "This review summarizes the current understanding of the functions of miR-33a/b and the progress in miRNA therapeutics for treatment of various diseases, including atherosclerosis." therapeutic target hsa-mir-33b Atherosclerosis 26645139 "This review summarizes the current understanding of the functions of miR-33a/b and the progress in miRNA therapeutics for treatment of various diseases, including atherosclerosis." therapeutic target hsa-mir-23b Diabetic Nephropathy 26646104 "Taken together, we showed for the first time that miR-23b acts as a suppressor of EMT in diabetic nephropathy through repressing PI3K-AKT signalling pathway activation by targeting HMGA2, which maybe a potential therapeutic target for diabetes-induced renal dysfunction." therapeutic target hsa-mir-103 "Carcinoma, Hepatocellular" 26646106 "These findings indicate that miR-103 potentially acts as an oncogene in HCC by inhibiting AKAP12 expression and raise the possibility that miR-103 increases telomerase activity by increasing PKC¦Á activity. Thus, miR-103 may represent a new potential diagnostic and therapeutic target for HCC treatment." therapeutic target hsa-mir-362 Kidney Neoplasms 26647877 "These results suggested that miR-362-3p functions as a tumor suppressor in RCC, and may serve as a potential molecular target in the treatment of RCC." therapeutic target hsa-mir-21 Diabetes Mellitus 26655730 These results suggest that endogenous miRNAs involved in the formation of IPCs from PPCs should be considered in the development of an effective cell transplant therapy for diabetes. therapeutic target hsa-mir-340 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 26656176 "Taken together, these data suggest that miR-340 impedes LSCC progression by targeting EZH2 with the possible mechanism to enhance the expression of anti-oncogene p27 and suppress PI3K/Akt activation, providing a novel target and a potential therapeutic pathway against LSCC." therapeutic target hsa-mir-204 Breast Neoplasms 26656364 Our study reveals that Sam68 is regulated by miR-204 and may play an important role in the self-renewal of BCSCs via activating the Wnt/beta-catenin pathway. Sam68 may represent a novel therapeutic target for breast cancer. therapeutic target hsa-mir-126 Thrombosis 26659078 Overexpressed miR-126 inhibits apoptosis of VECs and DVT through targeting the anti-apoptotic pathway PI3K/Akt via PIK3R2.GENERAL SIGNIFICANCE: These findings may provide a new target for the therapy of DVT. therapeutic target hsa-mir-215 Pancreatic Neoplasms 26662405 "These findings indicate that miR-215 may act as a tumor suppressor in pancreatic cancer cells, and could serve as a novel therapeutic target for miR-based therapy." therapeutic target hsa-mir-548d Breast Neoplasms 26663100 Our study showed that miR-548d-3p/TP53BP2 pathway is critically involved in the proliferation and apoptosis of breast cancer cells and may be new therapeutic target of breast cancer cells. therapeutic target hsa-mir-146a Allergy 26663191 "Further characterization of microRNA functions is important, as similar to other conditions, the modulation of microRNA expression could potentially be used for therapeutic purposes in allergic diseases in the future. In addition, miRNAs could be implemented as biomarkers for endotyping complex allergic conditions." therapeutic target hsa-mir-155 Allergy 26663191 "Further characterization of microRNA functions is important, as similar to other conditions, the modulation of microRNA expression could potentially be used for therapeutic purposes in allergic diseases in the future. In addition, miRNAs could be implemented as biomarkers for endotyping complex allergic conditions." therapeutic target hsa-mir-21 Allergy 26663191 "Further characterization of microRNA functions is important, as similar to other conditions, the modulation of microRNA expression could potentially be used for therapeutic purposes in allergic diseases in the future. In addition, miRNAs could be implemented as biomarkers for endotyping complex allergic conditions." therapeutic target hsa-mir-214 Breast Neoplasms 26666173 MiR-214 increased the sensitivity of breast cancer cells to TAM and FUL through inhibition of autophagy by targeting UCP2. MiR-214 shows potential as a novel therapeutic strategy for overcoming endocrine resistance in ER(+) breast cancers. therapeutic target hsa-mir-1 Arrhythmia 26671473 "We aim at emphasizing the relationship between miR-1 and ion channels and proteins involved in the process of arrhythmia. In addition, we will pay attention to its future therapeutic prospects." therapeutic target hsa-mir-21 Breast Neoplasms 26676464 "Taken together, we provide novel evidence that miR-21 knockdown suppresses cell growth, migration and invasion partly by inhibiting PI3K/AKT activation via direct targeting PIK3R1 and reversing EMT in breast cancer. p85¦Á downregulation defined a specific subgroup of breast cancer with shorter 5-year DFS and OS, which may require more aggressive treatment." therapeutic target hsa-mir-34a "Carcinoma, Breast, Triple Negative" 26676753 "Together, our results demonstrate that miR-34a exerts potent antitumorigenic effects in vitro and in vivo and suggests that miR-34a replacement therapy, which is currently being tested in human clinical trials, represents a promising therapeutic strategy for TNBC." therapeutic target hsa-mir-186 Multiple Myeloma 26679605 "Our collective results clearly indicate that miR-186 functions as a tumor suppressor in MM, supporting its potential as a therapeutic target for the disease." therapeutic target hsa-mir-134 Osteosarcoma 26681023 These findings indicate that miR-134 may act as a tumor suppressor in osteosarcoma and could serve as a novel therapeutic agent for miRNA-based therapy. therapeutic target hsa-mir-181c Glioblastoma 26682928 "our study found that miR-181c plays a key role in glioblastoma cell invasion, migration and mesenchymal transition suggesting potential therapeutic applications." therapeutic target hsa-mir-555 Viral Infectious Disease 26683768 These findings provide the first evidence for the role of miR-555 in PV replication and reveal that miR-555 could contribute to the development of antiviral therapeutic strategies against PV. therapeutic target hsa-mir-1290 "Leukemia, Lymphoblastic, Acute, B-Cell" 26684414 "Our results identify an expression profile of miR-151-5p, miR-451, and miR-1290 as a novel biomarker for outcome in pediatric precursor B-cell ALL patients, regardless of treatment protocol. The use of these markers may lead to improved risk stratification at diagnosis and allow early therapeutic interventions in an attempt to improve survival of high risk patients." therapeutic target hsa-mir-151 "Leukemia, Lymphoblastic, Acute, B-Cell" 26684414 "Our results identify an expression profile of miR-151-5p, miR-451, and miR-1290 as a novel biomarker for outcome in pediatric precursor B-cell ALL patients, regardless of treatment protocol. The use of these markers may lead to improved risk stratification at diagnosis and allow early therapeutic interventions in an attempt to improve survival of high risk patients." therapeutic target hsa-mir-451 "Leukemia, Lymphoblastic, Acute, B-Cell" 26684414 "Our results identify an expression profile of miR-151-5p, miR-451, and miR-1290 as a novel biomarker for outcome in pediatric precursor B-cell ALL patients, regardless of treatment protocol. The use of these markers may lead to improved risk stratification at diagnosis and allow early therapeutic interventions in an attempt to improve survival of high risk patients." therapeutic target hsa-mir-125b Lung Neoplasms 26686386 these results show tremendous promise of wt-p53 and miR-125b gene therapy using dual CD44/EGFR-targeting HA NP vector for effective treatment of lung cancer. therapeutic target hsa-mir-122 Cholangiocarcinoma 26686459 "MiR-122 expression was significantly weaker in CC tissues, and miR-122 overexpression might play pivotal roles in inhibiting proliferation, stimulating apoptosis and suppressing invasion of CC cells, suggesting a new target for CC diagnosis and treatment." therapeutic target hsa-mir-145 "Adenocarcinoma, Lung" 26687391 "MicroRNA 25, microRNA 145, and microRNA 210 as biomarkers for predicting the efficacy of maintenance treatment with pemetrexed in lung adenocarcinoma patients who are negative for epidermal growth factor receptor mutations or anaplastic lymphoma kinase translocations." therapeutic target hsa-mir-210 "Adenocarcinoma, Lung" 26687391 "MicroRNA 25, microRNA 145, and microRNA 210 as biomarkers for predicting the efficacy of maintenance treatment with pemetrexed in lung adenocarcinoma patients who are negative for epidermal growth factor receptor mutations or anaplastic lymphoma kinase translocations." therapeutic target hsa-mir-25 "Adenocarcinoma, Lung" 26687391 "MicroRNA 25, microRNA 145, and microRNA 210 as biomarkers for predicting the efficacy of maintenance treatment with pemetrexed in lung adenocarcinoma patients who are negative for epidermal growth factor receptor mutations or anaplastic lymphoma kinase translocations." therapeutic target hsa-mir-21 "Squamous Cell Carcinoma, Head and Neck" 26690371 miR-21 cooperates with CDK5 to promote EMT and invasion in HNSCC.This finding suggests that CDK5 may be an important cofactor for targeting when designing metastasis-blocking therapy by targeting STAT3/miR-21 axis with STAT3 inhibitor or miR-21 antisense oligonucleotide. This is the first demonstration of the novel role of STAT3/miR-21 axis and CDK5/CDK5R1 (p35) in metastasis of HNSCC. therapeutic target hsa-mir-1914 Colorectal Carcinoma 26695693 Plasma miR-1914* and -1915 interact with NFIX RNA and reduce its level in chemoresistant CRC cells to first-line chemotherapy. Up-regulation of miR-1914* and -1915 decreased the chemoresistance abilities of chemoresistant CRC cells. The plasma miR-1914* and -1915 may play a role in colorectal cancer therapy and diagnosis. therapeutic target hsa-mir-1915 Colorectal Carcinoma 26695693 Plasma miR-1914* and -1915 interact with NFIX RNA and reduce its level in chemoresistant CRC cells to first-line chemotherapy. Up-regulation of miR-1914* and -1915 decreased the chemoresistance abilities of chemoresistant CRC cells. The plasma miR-1914* and -1915 may play a role in colorectal cancer therapy and diagnosis. therapeutic target hsa-mir-155 Rheumatoid Arthritis 26697483 "Taken together, our results suggest that genome editing of miR-155 holds the potential as a therapeutic strategy in RA." therapeutic target hsa-mir-146a Allergic Rhinitis 26700406 miR-146a can enforce OVA-specific immunotherapy via inducing antigen-specific regulatory T cells. miR-146a may have therapeutic potential to be used in the immunotherapy of allergic diseases. therapeutic target hsa-mir-224 Breast Neoplasms 26701615 "Our results indicate that FUT4 and miR-224-3p are crucial regulators of cancer response to chemotherapy, and may serve as therapeutic targets to reverse chemotherapy resistance in breast cancer." therapeutic target hsa-mir-613 Prostate Neoplasms 26703210 "In conclusion, our study suggests that miR-613 functions as a tumor suppressor, partially through targeting Fzd7, and is a potential therapeutic target for prostate cancer." therapeutic target hsa-mir-195 Sepsis 26704614 "Silencing of miR-195 reduced multiple-organ injury and improved the survival in sepsis, and the protective effects of miR-195 inhibition were associated with upregulation of Bcl-2, Sirt1, and Pim-1. Thus, inhibition of miR-195 may represent a new therapeutic approach for sepsis." therapeutic target hsa-mir-127 Osteosarcoma 26707641 "Overall, the results revealed that miR-127-3p acts as a tumor suppressor and that its down-regulation in cancer may contribute to OS progression and metastasis, suggesting that miR-127-3p could be a potential therapeutic target in the treatment of OS." therapeutic target hsa-mir-127 "Carcinoma, Hepatocellular" 26708147 "In summary, we found that miR-127-5p suppressed NF-¦ÊB activity by directly targeting BLVRB in HCC cells, and this finding improves our understanding of the molecular mechanism of inflammation-induced HCC growth and proliferation and the successful inhibition of NF-¦ÊB activity by cancer treatment." therapeutic target hsa-mir-221 Glioma 26708164 increased pro-apoptotic effects were obtained with the co-administration of both anti-miRâ€?21 and anti-miRâ€?22 PNAs. therapeutic target hsa-let-7b "Leukemia, Lymphoblastic, Acute" 26708866 "In the patients with ALL, the expression of microRNA let-7b is regulated by methylation of CpG islands in the region of genomic promoter. The microRNA let-7b may act as a tumor suppressor, whose low expression is involved in ALL development, indicating the microRNA let-7b may become a new therapeutic target for ALL." therapeutic target hsa-mir-192 "Carcinoma, Hepatocellular" 26710269 "These results elucidate that the miR-192/-204-HOTTIP axis might be an important molecular pathway during hepatic cell tumorigenesis. Our data in clinical HCC samples highlight miR-192, miR-204 and HOTTIP with prognostic and potentially therapeutic implications." therapeutic target hsa-mir-204 "Carcinoma, Hepatocellular" 26710269 "These results elucidate that the miR-192/-204-HOTTIP axis might be an important molecular pathway during hepatic cell tumorigenesis. Our data in clinical HCC samples highlight miR-192, miR-203 and HOTTIP with prognostic and potentially therapeutic implications." therapeutic target hsa-let-7 Breast Neoplasms 26717565 "Taken together, these findings provide evidence that a miRNA expression signature can be developed to aid existing methods to determine the risk of recurrence for women with estrogen receptor positive breast cancers treated with endocrine therapy." therapeutic target hsa-mir-3648 Breast Neoplasms 26717565 "Taken together, these findings provide evidence that a miRNA expression signature can be developed to aid existing methods to determine the risk of recurrence for women with estrogen receptor positive breast cancers treated with endocrine therapy." therapeutic target hsa-mir-377 Breast Neoplasms 26717565 "Taken together, these findings provide evidence that a miRNA expression signature can be developed to aid existing methods to determine the risk of recurrence for women with estrogen receptor positive breast cancers treated with endocrine therapy." therapeutic target hsa-mir-548t Breast Neoplasms 26717565 "Taken together, these findings provide evidence that a miRNA expression signature can be developed to aid existing methods to determine the risk of recurrence for women with estrogen receptor positive breast cancers treated with endocrine therapy." therapeutic target hsa-mir-633b Breast Neoplasms 26717565 "Taken together, these findings provide evidence that a miRNA expression signature can be developed to aid existing methods to determine the risk of recurrence for women with estrogen receptor positive breast cancers treated with endocrine therapy." therapeutic target hsa-mir-340 Prostate Neoplasms 26718483 "Our findings suggest that miR-340 may function as a novel tumor suppressor in PCa through the MDM2-p53 pathway by directly targeting MDM2, which may be a promising miRNA-targeted therapy for PCa." therapeutic target hsa-mir-142 Fungal Keratitis 26720440 "This is, to our knowledge, the first report on comprehensive human corneal miRNA expression profile in fungal keratitis. Several miRNAs with high expression in fungal keratitis point toward their potential role in regulation of pathogenesis. Further insights in understanding their role in corneal wound inflammation may help design new therapeutic strategies." therapeutic target hsa-mir-155 Fungal Keratitis 26720440 "This is, to our knowledge, the first report on comprehensive human corneal miRNA expression profile in fungal keratitis. Several miRNAs with high expression in fungal keratitis point toward their potential role in regulation of pathogenesis. Further insights in understanding their role in corneal wound inflammation may help design new therapeutic strategies." therapeutic target hsa-mir-451a Fungal Keratitis 26720440 "This is, to our knowledge, the first report on comprehensive human corneal miRNA expression profile in fungal keratitis. Several miRNAs with high expression in fungal keratitis point toward their potential role in regulation of pathogenesis. Further insights in understanding their role in corneal wound inflammation may help design new therapeutic strategies." therapeutic target hsa-mir-511 Fungal Keratitis 26720440 "This is, to our knowledge, the first report on comprehensive human corneal miRNA expression profile in fungal keratitis. Several miRNAs with high expression in fungal keratitis point toward their potential role in regulation of pathogenesis. Further insights in understanding their role in corneal wound inflammation may help design new therapeutic strategies." therapeutic target hsa-mir-142 Inflammation 26721185 "These results suggest that PPAR¦Ã-mediated upregulation of miR-142-3p inhibits the HMGB1 expression, which,in turn, is a novel anti-inflammatory mechanism of PPAR¦Ã and has an important role in the treatment of inflammatory diseases." therapeutic target hsa-mir-16 Glioma 26722459 "In conclusion, MiR-16 mediated temozolomide-resistance in glioma cells by modulation of apoptosis via targeting Bcl-2, which suggesting that miR-16 and Bcl-2 would be potential therapeutic targets for glioma therapy." therapeutic target hsa-mir-212 Habitual Abortion 26722471 "In summary, we describe a unique myometrial miRNA expression pattern in human spontaneous preterm labor and discuss their possible role by predicting the target genes of each miRNA. Our results suggest that miRNA play a critical role in the process of partuition in myometrium. The identification of myometrial miRNA profile throws a new light upon the molecule mechanism and provides an insight into the potential diagnosis and treatment of preterm labor." therapeutic target hsa-mir-223 Habitual Abortion 26722471 "In summary, we describe a unique myometrial miRNA expression pattern in human spontaneous preterm labor and discuss their possible role by predicting the target genes of each miRNA. Our results suggest that miRNA play a critical role in the process of partuition in myometrium. The identification of myometrial miRNA profile throws a new light upon the molecule mechanism and provides an insight into the potential diagnosis and treatment of preterm labor." therapeutic target hsa-mir-5096 Habitual Abortion 26722471 "In summary, we describe a unique myometrial miRNA expression pattern in human spontaneous preterm labor and discuss their possible role by predicting the target genes of each miRNA. Our results suggest that miRNA play a critical role in the process of partuition in myometrium. The identification of myometrial miRNA profile throws a new light upon the molecule mechanism and provides an insight into the potential diagnosis and treatment of preterm labor." therapeutic target hsa-mir-503 Colorectal Carcinoma 26722476 "miR-503 inhibits cell proliferation and induces apoptosis by directly targeting E2F3 in CRC cells, indicating its potential application in CRC diagnosis and therapy." therapeutic target hsa-mir-203 Melanoma 26722525 "This study for the first time provided evidence that miR-203 could be an independent potential prognostic marker for patients with melanoma, and might even become a new therapeutic target for the treatment of melanoma." therapeutic target hsa-mir-542 Bladder Neoplasms 26723509 "MiR-542-3p and its target gene survivin may play crucial roles in the aggressive progression of human bladder cancer. More interestingly, miR-542-3p may function as a tumor suppressor and inhibit the proliferation of bladder cancer cells, implying that miR-542-3p-survivin signal axis might be a novel therapeutic target of this disease." therapeutic target hsa-mir-126 Rheumatoid Arthritis 26723864 "Our study demonstrated that down-regulation of miR-126 may indirectly inhibit PI3K/AKT signaling pathway to disrupt the imbalance between growth and death of RASFs by targeting PIK3R2, which may be clinically helpful to find therapeutic strategies directed toward miR-126 function for RA patients." therapeutic target hsa-mir-302b Breast Neoplasms 26744520 "Collectively, our findings reveal new insights underlying increased breast cancer mortality in obese individuals and provide a novel preclinical rationale to test the efficacy of Src inhibitors for breast cancer treatment." therapeutic target hsa-mir-26b Lung Neoplasms 26744864 "Taken together, our results demonstrate that miR-26b could suppress lung cancer cells proliferation, migration and invasion by directly negative regulation of COX-2. MiR-26b could serve as a novel potential marker for NSCLC therapy." therapeutic target hsa-mir-483 Glaucoma 26747772 "MicroRNA-483-3p has an inhibitory effect on ECM production in HTMCs through downregulating Smad4, which indicates that miR-483-3p may serve as a potential therapeutic target in glaucoma." therapeutic target hsa-mir-28 "Carcinoma, Hepatocellular" 26754294 A miR-28-5p-IL-34-macrophage feedback loop modulates HCC metastasis and serves as a novel prognostic factor as well as a therapeutic target for HCC. therapeutic target hsa-mir-208a Lung Neoplasms 26754670 "The present study provides evidence that miR-208a can affect the proliferation and radiosensitivity of human lung cancer cells by targeting p21 and can be transported by exosomes. Thus, miR-208a may serve as a potential therapeutic target for lung cancer patients." therapeutic target hsa-mir-511 "Leukemia, Myeloid, Acute" 26762252 Our study provides new insights into the understanding of miRNAs as functional mediators of the leukemogenic fusion gene MLL-AF9 and opens new opportunities to further investigate specific therapeutic options for AML via the miRNA level. therapeutic target hsa-mir-548c Ovarian Neoplasms 26762267 "These findings suggest that miR-548c directly downregulates Twist,and provide a novel mechanism for Twist upregulation in both endometrial and ovarian cancers. The use of miR-548c may hold therapeutic potential for the treatment of Twist-overexpressing tumors." therapeutic target hsa-mir-125a "Carcinoma, Cervical" 26766902 The molecular pathway of miR-125a-5p/ABL2 plays an important role in human cervical carcinoma. Targeting miR-125a-5p/ABL2 pathway may provide a new treatment strategy for patients with cervical carcinoma. therapeutic target hsa-mir-15a Uterine Leiomyosarcoma 26768834 "Differential miRNA signatures of ESS and LMS provide novel data regarding transcriptional regulation in these cancers, based on which new potential diagnostic markers, prognostic biomarkers and therapeutic targets may be explored. Differences in miRNA profiles of primary and metastatic LMS may improve our understanding of disease progression in this aggressive malignancy." therapeutic target hsa-mir-31 Uterine Leiomyosarcoma 26768834 "Differential miRNA signatures of ESS and LMS provide novel data regarding transcriptional regulation in these cancers, based on which new potential diagnostic markers, prognostic biomarkers and therapeutic targets may be explored. Differences in miRNA profiles of primary and metastatic LMS may improve our understanding of disease progression in this aggressive malignancy." therapeutic target hsa-mir-92a Uterine Leiomyosarcoma 26768834 "Differential miRNA signatures of ESS and LMS provide novel data regarding transcriptional regulation in these cancers, based on which new potential diagnostic markers, prognostic biomarkers and therapeutic targets may be explored. Differences in miRNA profiles of primary and metastatic LMS may improve our understanding of disease progression in this aggressive malignancy." therapeutic target hsa-mir-103 Prostate Neoplasms 26771762 "Therefore, our data collectively demonstrate that miR-103 is a proto-oncogene miRNA that can suppress prostate cancer proliferation and migration by down-regulating the oncogene PDCD10, indicating that miR-103 may represent a new potential diagnostic and therapeutic target for prostate cancer treatment." therapeutic target hsa-let-7 Hemangioma 26772808 microRNA-regulated pathways may play a role in infantile hemangioma development and progression and may be potentially useful for future development of novel therapeutic strategies for patients with infantile hemangioma. therapeutic target hsa-mir-9 Hemangioma 26772808 microRNA-regulated pathways may play a role in infantile hemangioma development and progression and may be potentially useful for future development of novel therapeutic strategies for patients with infantile hemangioma. therapeutic target hsa-mir-939 Hemangioma 26772808 microRNA-regulated pathways may play a role in infantile hemangioma development and progression and may be potentially useful for future development of novel therapeutic strategies for patients with infantile hemangioma. therapeutic target hsa-mir-367 "Carcinoma, Hepatocellular" 26772880 "This study indicated that miR-367 negatively regulates PTEN and promotes proliferation and invasion of HCC cells. Thus, miR-367 may represent a potential therapeutic target for HCC intervention." therapeutic target hsa-mir-1182 Bladder Neoplasms 26772886 "In conclusion, these results demonstrate that miR-1182 acts as a tumor suppressor and may be a potential biomarker for bladder cancer diagnosis and treatment." therapeutic target hsa-mir-206 "Carcinoma, Cervical" 26775359 "miR-206 may act not only as a novel diagnostic and prognostic marker, but also as a potential target for molecular therapy of cervical cancer." therapeutic target hsa-mir-451 "Carcinoma, Renal Cell" 26779781 MiR-451 acts as an anti-oncogene in RCC. Our data offer a new therapeutic target for further research. therapeutic target hsa-mir-509 Ovarian Neoplasms 26786897 Our data suggest that restoring certain dysregulated miRNAs to their normal levels could increase the therapeutic effects of anticancer drugs. therapeutic target hsa-mir-211 Melanoma 26787841 "These findings highlight a novel mechanism of melanoma formation: miR-211 is a molecular switch that is turned off in melanoma cells, raising the hope that in the future we might be able to turn the switch back on, thus providing a better treatment option for melanoma." therapeutic target hsa-mir-508 "Carcinoma, Gastric" 26801246 All these findings supports that canonical NF-¦ÊB signaling pathway is activated in GC at least by the inactivation of miR-508-3p and this might have therapeutic potential in GC treatment. therapeutic target hsa-mir-483 Thrombosis 26801758 "miR-483-3p is upregulated in EPCs from DVT patients, and it targets SRF to decrease EPCs migration and tube formation and increase apoptosis in vitro, while decrease EPCs homing and thrombus resolution in vivo. MiR-483-3p is a potential therapeutic target in DVT treatment." therapeutic target hsa-mir-206 "Carcinoma, Renal Cell" 26808577 All these results suggested that miR-206 functioned as a novel cell cycle regulator and tumor suppressor in ccRCC and could be considered as a potential target for ccRCC therapy. therapeutic target hsa-mir-205 Prostate Neoplasms 26813458 The miR-205/TP53INP1 mediated autophagy pathway might be an important molecular mechanism regulating radiosensitivity of prostate cancer cells and represents a potential therapeutic target for prostate cancer. therapeutic target hsa-mir-130a "Carcinoma, Hepatocellular" 26817584 "Our findings provide a molecular insight on understanding drug resistance in HCC cells. Therefore, activation of miR-130a-3p or inactivation of Smad4 could be a novel approach for the treatment of HCC." therapeutic target hsa-mir-107 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 26822763 NEAT1 plays an oncogenic role in the tumorigenesis of LSCC and may serve as a potential target for therapeutic intervention. therapeutic target hsa-mir-122 Cholangiocarcinoma 26825606 "The results indicate that HNF6 may serve as a tumor suppressor by regulating miR-122, and its overexpression may represent a mechanism-based therapy for CCA." therapeutic target hsa-mir-23b Gastric Neoplasms 26835790 "Our results indicated that plasma miR-23b was overexpressed in GC patients and high plasma miR-23b expression was associated with poor clinical outcome. Thus, plasma miR-23b may serve as a potential diagnostic biomarker and therapeutic target for GC." therapeutic target hsa-mir-124 Medulloblastoma 26840408 "In all, we have discovered miR-124 to be downregulated in instances of medulloblastoma in which Nur77 is upregulated, resulting in a proliferative state that abets cancer progression. This study provides evidence for increasing miR-124 expression as a potential therapy for cancers with elevated levels of Nur77." therapeutic target hsa-mir-24 Prostate Neoplasms 26847530 These findings provide evidence that miR-24 has a tumor suppressor role in prostate cancer and also targets p27 and p16 in prostate cancer cells. We propose that it may be a useful progression biomarker or focus of therapeutic intervention for this disease. therapeutic target hsa-mir-200c Cholangiocarcinoma 26855082 The ability of the combined PCX/miR-200c treatment to obstruct two migratory pathways represents a promising antimetastatic strategy in cholangiocarcinoma. therapeutic target hsa-mir-183 "Carcinoma, Cervical" 26873866 "In conclusion, our study revealed that miR-183 might be a tumor suppressor via inhibiting the invasion and metastasis of cervical cancer cells through targeting MMP-9, indicating that miR-183 may be a novel potential therapeutic target for cervical cancer." therapeutic target hsa-mir-21 Asthma 26874829 "This study suggested that serum miRNA-21 is stable and detectable in serum of asthmatic children, which could promise potential biomarker in diagnosis as well as in response to therapy of asthma." therapeutic target hsa-mir-874 Colorectal Carcinoma 26875895 "These data demonstrate that miR-874 functions as a tumor suppressor by repression of STAT3, suggesting its potential therapeutic value in CRC treatment." therapeutic target hsa-mir-100 Multiple Sclerosis 26943961 Dicer and microRNA expression in multiple sclerosis and response to interferon therapy. therapeutic target hsa-mir-107 Multiple Sclerosis 26943961 Dicer and microRNA expression in multiple sclerosis and response to interferon therapy. therapeutic target hsa-mir-145 Multiple Sclerosis 26943961 Dicer and microRNA expression in multiple sclerosis and response to interferon therapy. therapeutic target hsa-mir-146b Multiple Sclerosis 26943961 Dicer and microRNA expression in multiple sclerosis and response to interferon therapy. therapeutic target hsa-mir-323 Multiple Sclerosis 26943961 Dicer and microRNA expression in multiple sclerosis and response to interferon therapy. therapeutic target hsa-mir-3614 Multiple Sclerosis 26943961 Dicer and microRNA expression in multiple sclerosis and response to interferon therapy. therapeutic target hsa-mir-369 Multiple Sclerosis 26943961 Dicer and microRNA expression in multiple sclerosis and response to interferon therapy. therapeutic target hsa-mir-494 Multiple Sclerosis 26943961 Dicer and microRNA expression in multiple sclerosis and response to interferon therapy. therapeutic target hsa-mir-874 Multiple Sclerosis 26943961 Dicer and microRNA expression in multiple sclerosis and response to interferon therapy. therapeutic target hsa-mir-9 Multiple Sclerosis 26943961 Dicer and microRNA expression in multiple sclerosis and response to interferon therapy. therapeutic target hsa-mir-146a Atherosclerosis 26956647 delivery of microRNA (miR)-146a and miR-181b with an E-selectin-targeting multistage vector (ESTA-MSV) to inflamed endothelium covering atherosclerotic plaques inhibits atherosclerosis therapeutic target hsa-mir-181b Atherosclerosis 26956647 delivery of microRNA (miR)-146a and miR-181b with an E-selectin-targeting multistage vector (ESTA-MSV) to inflamed endothelium covering atherosclerotic plaques inhibits atherosclerosis therapeutic target hsa-mir-146b Glioma 26983831 a novel treatment whereby mesenchymal stromal cells were employed to package tumor-suppressing miR-146b into exosomes therapeutic target hsa-mir-708 Asthma 26998837 These results demonstrate that miR-708 and miR-140-3p exert distinct effects on inflammation-associated gene expression and biological function of ASM cells. Targeting these miRNA networks may provide a novel therapeutic mechanism to down-regulate airway inflammation and ASM proliferation in asthma. therapeutic target hsa-mir-124 Stroke 27031810 These neuroprotective and anti-inflammatory effects of the early miR-124 treatment were pronounced during the first week with Arg-1. therapeutic target hsa-mir-122 "Carcinoma, Hepatocellular" 27059462 "MicroRNA profiling of distinct tumor foci, coupled with methods that address within-subject tumor heterogeneity, has the potential to significantly improve prediction of HCC recurrence post-transplantation. The development of a clinically applicable HCC biomarker would inform treatment options for patients and contribute to liver transplant selection criteria for practitioners." therapeutic target hsa-mir-126 "Carcinoma, Hepatocellular" 27059462 "MicroRNA profiling of distinct tumor foci, coupled with methods that address within-subject tumor heterogeneity, has the potential to significantly improve prediction of HCC recurrence post-transplantation. The development of a clinically applicable HCC biomarker would inform treatment options for patients and contribute to liver transplant selection criteria for practitioners." therapeutic target hsa-mir-15a "Carcinoma, Hepatocellular" 27059462 "MicroRNA profiling of distinct tumor foci, coupled with methods that address within-subject tumor heterogeneity, has the potential to significantly improve prediction of HCC recurrence post-transplantation. The development of a clinically applicable HCC biomarker would inform treatment options for patients and contribute to liver transplant selection criteria for practitioners." therapeutic target hsa-mir-22 "Carcinoma, Hepatocellular" 27059462 "MicroRNA profiling of distinct tumor foci, coupled with methods that address within-subject tumor heterogeneity, has the potential to significantly improve prediction of HCC recurrence post-transplantation. The development of a clinically applicable HCC biomarker would inform treatment options for patients and contribute to liver transplant selection criteria for practitioners." therapeutic target hsa-mir-30a "Carcinoma, Hepatocellular" 27059462 "MicroRNA profiling of distinct tumor foci, coupled with methods that address within-subject tumor heterogeneity, has the potential to significantly improve prediction of HCC recurrence post-transplantation. The development of a clinically applicable HCC biomarker would inform treatment options for patients and contribute to liver transplant selection criteria for practitioners." therapeutic target hsa-mir-146a Melanoma 27059647 "two miRNAs that are particularly relevant in human melanoma progression, miR-146a and miR-214." therapeutic target hsa-mir-205 Breast Neoplasms 27064979 Variations in serum miRNA levels during NAC treatment may be therapeutically significant for predicting response and survival outcomes. therapeutic target hsa-mir-21 Breast Neoplasms 27064979 Variations in serum miRNA levels during NAC treatment may be therapeutically significant for predicting response and survival outcomes. therapeutic target hsa-mir-3200 Breast Neoplasms 27064979 Variations in serum miRNA levels during NAC treatment may be therapeutically significant for predicting response and survival outcomes. therapeutic target hsa-mir-451 Breast Neoplasms 27064979 Variations in serum miRNA levels during NAC treatment may be therapeutically significant for predicting response and survival outcomes. therapeutic target hsa-mir-21 Glioblastoma 27079911 Here we show that rationally designed hammerhead ribozymes and DNAzymes can target miR-21 and/or its precursors. therapeutic target hsa-mir-21 Glioma 27079911 Here we show that rationally designed hammerhead ribozymes and DNAzymes can target miR-21 and/or its precursors. therapeutic target hsa-mir-24 Diabetic Vasculopathy 27085480 elevation of miR-24 in vascular system may be a novel therapeutic strategy to prevent the development of diabetic atherosclerosis. therapeutic target hsa-mir-23a Acute Erythroid Leukemia 27086927 "indicating the therapeutic significance of miR-23a, -27a and -24 for AEL treatment." therapeutic target hsa-mir-24 Acute Erythroid Leukemia 27086927 "indicating the therapeutic significance of miR-23a, -27a and -24 for AEL treatment." therapeutic target hsa-mir-27a Acute Erythroid Leukemia 27086927 "indicating the therapeutic significance of miR-23a, -27a and -24 for AEL treatment." therapeutic target hsa-mir-487b Lung Neoplasms 27097129 miR-487b-5p inhibition can be further explored as a chemotherapy target in the treatment of TMZ-resistant lung carcinoma. therapeutic target hsa-mir-17 Prostate Neoplasms 27125502 RNA nanoparticles were constructed by bottom-up self-assembly containing the anti-prostate-specific membrane antigen (PSMA) RNA aptamer as a targeting ligand and anti-miR17 or anti-miR21 as therapeutic modules. therapeutic target hsa-mir-21 Prostate Neoplasms 27125502 RNA nanoparticles were constructed by bottom-up self-assembly containing the anti-prostate-specific membrane antigen (PSMA) RNA aptamer as a targeting ligand and anti-miR17 or anti-miR21 as therapeutic modules. therapeutic target hsa-mir-96 "Carcinoma, Breast, Triple Negative" 27170187 3 directly engages pri-miR-96 in breast cancer cells. therapeutic target hsa-mir-29b Multiple Myeloma 27196750 miR-29b-based epi-therapeutic approaches in the treatment of this malignancy therapeutic target hsa-mir-124 Breast Neoplasms 27266580 miR-124-M-Oba may have potential applications in breast cancer therapy. therapeutic target hsa-mir-21 Glioblastoma 27277750 co-delivery of anti-miR-21 significantly improved accumulation of LPNs in the nucleus of U87MG cells. therapeutic target hsa-mir-150 "Leukemia, Myeloid, Acute" 27280396 "using FLT3L-guided miR-150-based nanoparticles, to treat FLT3-overexpressing AML with high efficacy and minimal side effects." therapeutic target hsa-mir-181a Mitochondrial Metabolism Disease 27281615 Knock down of endogenous miR-181a accelerates the autophagic degradation of damaged mitochondria. therapeutic target hsa-mir-222 Breast Neoplasms 27282281 downregulation of miR-222 in MCF-7/Adr increased sensitivity to Adr and Adr-induced apoptosis therapeutic target hsa-mir-215 Cervical Neoplasms 27295129 "dysregulation of miR-29C, miR-34A, miR-98, and miR-215" therapeutic target hsa-mir-29c Cervical Neoplasms 27295129 "dysregulation of miR-29C, miR-34A, miR-98, and miR-215" therapeutic target hsa-mir-34a Cervical Neoplasms 27295129 "dysregulation of miR-29C, miR-34A, miR-98, and miR-215" therapeutic target hsa-mir-98 Cervical Neoplasms 27295129 "dysregulation of miR-29C, miR-34A, miR-98, and miR-215" therapeutic target hsa-mir-155 Lung Neoplasms 27315591 Inhibition of microRNA-155 sensitizes lung cancer cells to irradiation therapeutic target hsa-mir-150 Graft-Versus-Host Disease 27329362 microRNA-150 (miR-150) induces immunological tolerance in CD4(+) T cells after transplantation therapeutic target hsa-mir-18a "Carcinoma, Breast, Triple Negative" 27338043 MiR-18a overexpression significantly increased PTX IC50 and reduced PTX induced cell apoptosis therapeutic target hsa-mir-93 Age-Related Macular Degeneration 27349759 these results highlight the therapeutic potential of miR-93 therapeutic target hsa-mir-21 Glioblastoma 27355932 Anti-cancer effect of R3V6 peptide-mediated delivery of an anti-microRNA-21 antisense-oligodeoxynucleotide in a glioblastoma animal model. therapeutic target hsa-mir-20a Gastric Neoplasms 27357419 Altering miRâ€?0a expression may be a potential therapeutic strategy for the treatment of chemoresistance in GC in the future. therapeutic target hsa-mir-221 "Leukemia, Lymphoblastic, Acute" 27358112 Niche-influenced miR-221/222 may define a novel therapeutic target in ALL therapeutic target hsa-mir-222 "Leukemia, Lymphoblastic, Acute" 27358112 Niche-influenced miR-221/222 may define a novel therapeutic target in ALL therapeutic target hsa-mir-30e Gastric Neoplasms 27372603 DIM may through the miR-30e-ATG5 modulating autophagy inhibit the proliferation of gastric cancer cells. therapeutic target hsa-mir-493 Breast Neoplasms 27375041 The miR-493-5p/FUT4 pathway has therapeutic potential in breast cancer. therapeutic target hsa-mir-30e Glioblastoma 27388765 "Collectively, combination of miR-30e and PAC is a promising therapeutic strategy to inhibit autophagy and increase apoptosis in GSC and SNB19 cells." therapeutic target hsa-mir-210 Acute Myocardial Infarction 27392480 "HAR could reduce the infarction area, alleviate the interstitial fibrosis and improve the cardiac function of AMI rats. Those effects could be related to promoting myocardium angiogenesis of HAR by up-regulating miR-210 and VEGF." therapeutic target hsa-mir-155 Colitis 27395764 IL-10/miR-155/SHIP-1 pathways play a critical role in commensal bacteria induced colitis and miR-15 therapeutic target hsa-mir-214 Breast Neoplasms 27422604 "In conclusion, miR-214 functions as a tumor suppressor by regulating the RFWD2-p53 cascade, thus delivery of miR-214 analogs could be a potential adjunct therapy in breast cancer harboring wild type p53." therapeutic target hsa-mir-21 Neoplasms [unspecific] 27428511 Targeted inhibition of oncogenic miR-21 maturation with designed RNA-binding proteins therapeutic target hsa-mir-7 Melanoma 27448964 "Collectively, our study demonstrated that miR-7 could reverse the resistance to BRAF inhibitors in certain vemurafenib resistant melanoma cell lines." therapeutic target hsa-mir-145 "Carcinoma, Colon" 27482839 "The results in this work show that miR-145 has been effectively delivered to colon carcinomas through a PLGA/PEI/HA vehicle, indicating a promising miRNA replacement therapy strategy." therapeutic target hsa-mir-122 Asthma 27485847 "First clinical trials using the blockade of liver specific miR-122 showed very promising results in the treatment of chronic hepatitis C virus infection. Results of preclinical and animal studies are also promising providing future rationale for the development of new therapeutics for various internal diseases including heart failure, bronchial asthma or inflammatory bowel diseases." therapeutic target hsa-mir-122 Chronic Hepatitis C 27485847 "First clinical trials using the blockade of liver specific miR-122 showed very promising results in the treatment of chronic hepatitis C virus infection. Results of preclinical and animal studies are also promising providing future rationale for the development of new therapeutics for various internal diseases including heart failure, bronchial asthma or inflammatory bowel diseases." therapeutic target hsa-mir-122 Heart Failure 27485847 "First clinical trials using the blockade of liver specific miR-122 showed very promising results in the treatment of chronic hepatitis C virus infection. Results of preclinical and animal studies are also promising providing future rationale for the development of new therapeutics for various internal diseases including heart failure, bronchial asthma or inflammatory bowel diseases." therapeutic target hsa-mir-122 Inflammatory Bowel Diseases 27485847 "First clinical trials using the blockade of liver specific miR-122 showed very promising results in the treatment of chronic hepatitis C virus infection. Results of preclinical and animal studies are also promising providing future rationale for the development of new therapeutics for various internal diseases including heart failure, bronchial asthma or inflammatory bowel diseases." therapeutic target hsa-mir-145 Pancreatic Neoplasms 27507554 "miR-145 re-expression resulted in downregulation of MUC13, HER2, pAKT, and inhibition of cell proliferation, clonogenicity, migration, and invasion of pancreatic cancer cells." therapeutic target hsa-mir-21 Glioblastoma 27508339 Coinhibition of miR-21 and miR-10b significantly reduced the number of viable cells (by 24%; p < 0.01) and increased (2.9-fold) cell cycle arrest at G2/M phase upon Temozolomide treatment in U87 MG cells. therapeutic target hsa-mir-146b "Carcinoma, Thyroid, Papillary" 27533309 "In conjunction with current therapeutic regimens, targeting the miR-146b-IRAK1 axis may provide a potential approach for PTC management." therapeutic target hsa-mir-146b Neoplasms [unspecific] 27533309 "In conjunction with current therapeutic regimens, targeting the miR-146b-IRAK1 axis may provide a potential approach for PTC management." therapeutic target hsa-mir-223 Periodontal Diseases 27552373 "Knowledge gained from future studies will be beneficial in developing alternative therapeutic approaches, especially ones that use miRNA delivery systems to treat periodontal disease" therapeutic target hsa-mir-22 Rhabdomyosarcoma 27569217 Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma. therapeutic target hsa-mir-34a Glioblastoma 27569663 Functionalized nanogels carrying an anticancer microRNA for glioblastoma therapy. therapeutic target hsa-let-7i Neoplasms [unspecific] 27588466 Involvement of let-7 microRNA for the therapeutic effects of Rhenium-188-embedded liposomal nanoparticles on orthotopic human head and neck cancer model. therapeutic target hsa-mir-143 Obesity 27623943 Tumour biology of obesity-related cancers: understanding the molecular concept for better diagnosis and treatment. therapeutic target hsa-mir-1246 Corneal Neovascularization 27625050 Curcumin inhibits angiogenesis by up-regulation of microRNA-1275 and microRNA-1246: a promising therapy for treatment of corneal neovascularization. therapeutic target hsa-mir-1275 Corneal Neovascularization 27625050 Curcumin inhibits angiogenesis by up-regulation of microRNA-1275 and microRNA-1246: a promising therapy for treatment of corneal neovascularization. therapeutic target hsa-mir-145 Neoplasms [unspecific] 27655328 "our results indicated that mir-145, through targeting its common potential targets, may significantly contribute to tumor pathogenesis in distinct cancer types and might serve as an important target for cancer therapy" therapeutic target hsa-mir-193a Neoplasms [unspecific] 27669434 the broader applicability of using miR-193a-3p as a therapeutic agent to target KRas-mutant cancer therapeutic target hsa-mir-495 Neoplasms [unspecific] 27697751 MiR-495 functions as an adjuvant to radiation therapy by reducing the radiation-induced bystander effect. therapeutic target hsa-let-7a Colorectal Carcinoma 27737877 Our data support the role of let-7a in suppressing antitumor immunity in colorectal cancer and suggest let-7a as a potential target of immunotherapy therapeutic target hsa-mir-124 Glioblastoma 27765835 Immune modulatory nanoparticle therapeutics for intracerebral glioma. therapeutic target hsa-mir-155 Allergic Asthma 27783037 miR-155: A Novel Target in Allergic Asthma. therapeutic target hsa-mir-129 Neoplasms [unspecific] 27802440 we summarized the roles of miR-129 family members and their target genes in tumorigenesis and clinical treatment of human cancers therapeutic target hsa-mir-126 Kidney Injury 27832640 "non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), have significant potential to aid the development of diagnostic and therapeutic strategies of AKI" therapeutic target hsa-mir-127 Kidney Injury 27832640 "non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), have significant potential to aid the development of diagnostic and therapeutic strategies of AKI" therapeutic target hsa-mir-150 Kidney Injury 27832640 "non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), have significant potential to aid the development of diagnostic and therapeutic strategies of AKI" therapeutic target hsa-mir-21 Kidney Injury 27832640 "non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), have significant potential to aid the development of diagnostic and therapeutic strategies of AKI" therapeutic target hsa-mir-24 Kidney Injury 27832640 "non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), have significant potential to aid the development of diagnostic and therapeutic strategies of AKI" therapeutic target hsa-mir-30 Kidney Injury 27832640 "non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), have significant potential to aid the development of diagnostic and therapeutic strategies of AKI" therapeutic target hsa-mir-494 Kidney Injury 27832640 "non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), have significant potential to aid the development of diagnostic and therapeutic strategies of AKI" therapeutic target hsa-mir-687 Kidney Injury 27832640 "non-coding RNAs (ncRNAs), such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), have significant potential to aid the development of diagnostic and therapeutic strategies of AKI" therapeutic target hsa-mir-106a Rheumatoid Arthritis 27834806 "X-linked miRNAs, in the context of sex differences, might provide novel insight into new molecular mechanisms and potential therapeutic targets in RA for disease treatment and prevention" therapeutic target hsa-mir-221 Rheumatoid Arthritis 27834806 "X-linked miRNAs, in the context of sex differences, might provide novel insight into new molecular mechanisms and potential therapeutic targets in RA for disease treatment and prevention" therapeutic target hsa-mir-222 Rheumatoid Arthritis 27834806 "X-linked miRNAs, in the context of sex differences, might provide novel insight into new molecular mechanisms and potential therapeutic targets in RA for disease treatment and prevention" therapeutic target hsa-mir-532 Rheumatoid Arthritis 27834806 "X-linked miRNAs, in the context of sex differences, might provide novel insight into new molecular mechanisms and potential therapeutic targets in RA for disease treatment and prevention" therapeutic target hsa-mir-92a Rheumatoid Arthritis 27834806 "X-linked miRNAs, in the context of sex differences, might provide novel insight into new molecular mechanisms and potential therapeutic targets in RA for disease treatment and prevention" therapeutic target hsa-mir-98 Rheumatoid Arthritis 27834806 "X-linked miRNAs, in the context of sex differences, might provide novel insight into new molecular mechanisms and potential therapeutic targets in RA for disease treatment and prevention" therapeutic target hsa-mir-122 Diabetes Mellitus 27966196 "MicroRNAs 33, 122, and 208: a potential novel targets in the treatment of obesity, diabetes, and heart-related diseases." therapeutic target hsa-mir-208 Diabetes Mellitus 27966196 "MicroRNAs 33, 122, and 208: a potential novel targets in the treatment of obesity, diabetes, and heart-related diseases." therapeutic target hsa-mir-33 Diabetes Mellitus 27966196 "MicroRNAs 33, 122, and 208: a potential novel targets in the treatment of obesity, diabetes, and heart-related diseases." therapeutic target hsa-mir-34a Neoplasms [unspecific] 28010900 Emergence of miR-34a in radiation therapy. therapeutic target hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 28053325 Effects of miRNA-15 and miRNA-16 expression replacement in chronic lymphocytic leukemia: implication for therapy. therapeutic target hsa-mir-16 "Leukemia, Lymphocytic, Chronic, B-Cell" 28053325 Effects of miRNA-15 and miRNA-16 expression replacement in chronic lymphocytic leukemia: implication for therapy. therapeutic target hsa-mir-21 "Carcinoma, Breast" 28067096 Differential response of normal and transformed mammary epithelial cells to combined treatment of anti-miR-21 and radiation. therapeutic target hsa-mir-30a Schizophrenia 28072411 The early growth response protein 1-miR-30a-5p-neurogenic differentiation factor 1 axis as a novel biomarker for schizophrenia diagnosis and treatment monitoring. therapeutic target hsa-mir-21 Hypertrophic Scar 28075443 MicroRNA expression signature and the therapeutic effect of the microRNA?21 antagomir in hypertrophic scarring. therapeutic target hsa-mir-21 Neoplasms [unspecific] 28096467 "Our results not only elucidate miR-21-mediated radioresistance, but also provide potential new targets for improving radiotherapy" therapeutic target hsa-mir-1 Intrahepatic Cholangiocarcinoma 28098904 "has-miR-96, has-miR-1 and has-miR-25, may be potential therapeutic targets for the future treatment of ICC" therapeutic target hsa-mir-25 Intrahepatic Cholangiocarcinoma 28098904 "has-miR-96, has-miR-1 and has-miR-25, may be potential therapeutic targets for the future treatment of ICC" therapeutic target hsa-mir-96 Intrahepatic Cholangiocarcinoma 28098904 "has-miR-96, has-miR-1 and has-miR-25, may be potential therapeutic targets for the future treatment of ICC" therapeutic target hsa-mir-647 "Carcinoma, Gastric" 28098914 "miR-647 exerts powerful antitumorigenic effects in?vitro and in?vivo, and may represent a promising therapeutic agent against GC" therapeutic target hsa-mir-21 Glioblastoma 28109960 RNA Nanoparticle-Based Targeted Therapy for Glioblastoma through Inhibition of Oncogenic miR-21. therapeutic target hsa-mir-141 "Carcinoma, Colon" 28112364 MicroRNA-141 inhibits tumor growth and minimizes therapy resistance in colorectal cancer. therapeutic target hsa-mir-206 Alzheimer Disease 28123152 "miR-206-3p is involved in the anti-dementia effects of donepezil, and could be a novel pharmacological target for treating AD" therapeutic target hsa-mir-21 Diabetic Nephropathy 28129112 Therapeutic miR-21 Silencing Ameliorates Diabetic Kidney Disease in Mice. therapeutic target hsa-mir-31 "Carcinoma, Colon" 28147317 EZH2 expression is a prognostic biomarker in patients with colorectal cancer treated with anti-EGFR therapeutics. therapeutic target hsa-mir-1254 "Squamous Cell Carcinoma, Oral" 28161631 miR-1254 is a potential target for the treatment of OSCCs therapeutic target hsa-let-7b Melanoma 28167449 Curcumin and treatment of melanoma: The potential role of microRNAs. therapeutic target hsa-mir-21 Melanoma 28167449 Curcumin and treatment of melanoma: The potential role of microRNAs. therapeutic target hsa-mir-122 Neoplasms [unspecific] 28209991 MicroRNA therapeutics: towards a new era for the management of cancer and other diseases. therapeutic target hsa-mir-34 Neoplasms [unspecific] 28209991 MicroRNA therapeutics: towards a new era for the management of cancer and other diseases. therapeutic target hsa-mir-126 "Carcinoma, Renal Cell" 28257806 Pseudohypoxia induced by miR-126 deactivation promotes migration and therapeutic resistance in renal cell carcinoma. therapeutic target hsa-mir-146b "Carcinoma, Thyroid, Papillary" 28294980 MicroRNA-146b: A Novel Biomarker and Therapeutic Target for Human Papillary Thyroid Cancer. therapeutic target hsa-mir-223 Hematologic Neoplasms 28322994 "The role of miRNA-223 in cancer: Function, diagnosis and therapy." therapeutic target hsa-mir-27b Neoplasms [unspecific] 28351320 Promising therapeutic role of miR-27b in tumor. therapeutic target hsa-mir-30a Neoplasms [unspecific] 28359057 miR-30a may serve as a potential target in the diagnosis and therapy of human cancer therapeutic target hsa-mir-383 Spinal Cord Injuries 28365701 Suppression of MicroRNA-383 Enhances Therapeutic Potential of Human Bone-Marrow-Derived Mesenchymal Stem Cells in Treating Spinal Cord Injury via GDNF. therapeutic target hsa-mir-149 Colorectal Carcinoma 28370854 miR-149 may serve as a therapeutic target for colorectal cancer treatment therapeutic target hsa-mir-138 Malignant Neoplasms [unspecific] 28378633 MiR-138: A promising therapeutic target for cancer. therapeutic target hsa-mir-17 Kidney Diseases [unspecific] 28399020 Therapeutic microRNAs in polycystic kidney disease. therapeutic target hsa-mir-146 Cardiovascular Diseases [unspecific] 28407626 Exogenous miRNA-146a Enhances the Therapeutic Efficacy of Human Mesenchymal Stem Cells by Increasing Vascular Endothelial Growth Factor Secretion in the Ischemia/Reperfusion-Injured Heart. therapeutic target hsa-mir-126 Diabetes Mellitus 28440196 miR-126 as a Therapeutic Agent for Diabetes Mellitus. therapeutic target hsa-mir-210 Neurilemmoma 28440459 miR-210 could be a potential marker for judging tumor malignancy and be taken as an effective target for clinical auxiliary treatment of neurilemmoma therapeutic target hsa-mir-21 Pancreatic Neoplasms 28444967 Co-delivery of microRNA-21 antisense oligonucleotides and gemcitabine using nanomedicine for pancreatic cancer therapy. therapeutic target hsa-mir-143 Neoplasms [unspecific] 28448866 Function of microRNA-143 in different signal pathways in cancer: New insights into cancer therapy. therapeutic target hsa-mir-92a Diabetes Mellitus 28462946 Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice. therapeutic target hsa-mir-130a Myocardial Infarction 28498815 The optimization of cell therapy by combinational application with apicidin-treated mesenchymal stem cells after myocardial infarction. therapeutic target hsa-mir-373 Glioma 28617546 Down-expression of miR-373 predicts poor prognosis of glioma and could be a potential therapeutic target. therapeutic target hsa-mir-200c Uterine Carcinosarcoma 28620240 miR-200c-driven Mesenchymal-To-Epithelial Transition is a Therapeutic Target in Uterine Carcinosarcomas. therapeutic target hsa-mir-143 "Carcinoma, Breast, Triple Negative" 28621239 A microRNA signature associated with pathological complete response to novel neoadjuvant therapy regimen in triple-negative breast cancer. therapeutic target hsa-mir-30a "Carcinoma, Breast, Triple Negative" 28621239 A microRNA signature associated with pathological complete response to novel neoadjuvant therapy regimen in triple-negative breast cancer. therapeutic target hsa-mir-770 "Carcinoma, Breast, Triple Negative" 28621239 A microRNA signature associated with pathological complete response to novel neoadjuvant therapy regimen in triple-negative breast cancer. therapeutic target hsa-mir-9 "Carcinoma, Breast, Triple Negative" 28621239 A microRNA signature associated with pathological complete response to novel neoadjuvant therapy regimen in triple-negative breast cancer. therapeutic target hsa-mir-375 "Carcinoma, Hepatocellular" 28624193 MiR-375 and Doxorubicin Co-delivered by Liposomes for Combination Therapy of Hepatocellular Carcinoma. therapeutic target hsa-mir-499 Cardiovascular Diseases [unspecific] 28627982 miRNAs as potential therapeutic targets and diagnostic biomarkers for cardiovascular disease with a particular focus on WO2010091204. therapeutic target hsa-mir-629 Breast Neoplasms 28629464 miR-629-3p may serve as a novel biomarker and potential therapeutic target for lung metastases of triple-negative breast cancer. therapeutic target hsa-mir-15a "Lymphoma, Follicular" 28653191 MicroRNA Dysregulation to Identify Novel Therapeutic Targets. therapeutic target hsa-mir-26a Glaucoma 28685590 miR-26a plays an essential role in the formation of filtering tract scar and function as a potential drug target therapeutic target hsa-mir-503 Endometriosis 28720098 "Arcyriaflavin a, a cyclin D1-cyclin-dependent kinase4 inhibitor, induces apoptosis and inhibits proliferation of human endometriotic stromal cells: a potential therapeutic agent in endometriosis" therapeutic target hsa-mir-140 "Carcinoma, Lung, Non-Small-Cell" 28739724 Therapeutic Role of MiR-140-5p for the Treatment of Non-small Cell Lung Cancer. therapeutic target hsa-mir-433 Endomyocardial Fibrosis 28740551 Modulating microRNAs as Novel Therapeutic Targets in Cardiac Fibrosis. therapeutic target hsa-mir-145 "Carcinoma, Ovarian" 28804560 Using miR-145 mimics may be a rational approach for therapeutic applications in ovarian carcinoma in the future therapeutic target hsa-mir-132 Wound Healing 28807666 MicroRNA-132 with Therapeutic Potential in Chronic Wounds. therapeutic target hsa-mir-122 "Leukemia, Myeloid, Acute" 28822593 Decreased expression of microRNA-122 is associated with an unfavorable prognosis in childhood acute myeloid leukemia and function analysis indicates a therapeutic potential. therapeutic target hsa-mir-122 Cholangiocarcinoma 28832247 "miRNA profiling for diagnosis, prognosis and stratification of cancer treatment in cholangiocarcinoma." therapeutic target hsa-mir-34b "Carcinoma, Thyroid" 28840508 It could be a target for developing treatment strategies of thyroid carcinoma with aggressive clinical behaviour therapeutic target hsa-mir-21 Glioblastoma 28840962 Biomarkers and therapeutic advances in glioblastoma multiforme. therapeutic target hsa-mir-155 Intraductal Papillary Mucinous Neoplasms 28938594 these miRNAs might serve as new risk biomarkers of IPMN and could be useful for future targeted therapies therapeutic target hsa-mir-137 Bipolar Disorder 28969861 "miRNA findings in BD significantly vary between studies, but are consistent to suggest a key role for these molecules in BD's pathophysiology and treatment, particularly miR-34a and miR-137" therapeutic target hsa-mir-34a Bipolar Disorder 28969861 "miRNA findings in BD significantly vary between studies, but are consistent to suggest a key role for these molecules in BD's pathophysiology and treatment, particularly miR-34a and miR-137" therapeutic target hsa-mir-20a Myeloma 28979138 miR-20a plays a crucial role in the biology of MM and represents a potential target for novel therapies for MM patients therapeutic target hsa-mir-122 Chronic Hepatitis C 28993299 Circulating microRNAs as a biomarker to predict therapy efficacy in hepatitis C patients with different genotypes. therapeutic target hsa-mir-124a Glioblastoma 29016843 Mesenchymal stem cells as natural biofactories for exosomes carrying miR-124a in the treatment of gliomas. therapeutic target hsa-mir-132 Colon Neoplasms 29017096 miR-132 as a promising therapeutic candidate to control autoimmune inflammation and tumorigenesis in CAC patients therapeutic target hsa-mir-449a Neoplasms [unspecific] 29023247 miR-449a: a potential therapeutic agent for cancer. therapeutic target hsa-mir-146a "Carcinoma, Thyroid, Papillary" 29048684 miR-146a and miR-146b in the diagnosis and prognosis of papillary thyroid carcinoma. therapeutic target hsa-mir-146b "Carcinoma, Thyroid, Papillary" 29048684 miR-146a and miR-146b in the diagnosis and prognosis of papillary thyroid carcinoma. therapeutic target hsa-mir-134 Epilepsy 29069823 MicroRNA-134 plasma levels before and after treatment with valproic acid for epilepsy patients. therapeutic target hsa-mir-16 Cardiovascular Diseases [unspecific] 29104843 miR-16 was a potential therapeutic target by participating in the Ang II-associated multiple signaling pathways in cardiovascular diseases therapeutic target hsa-mir-155 Rheumatoid Arthritis 29105307 Hopefully the information obtained will benefit the development of novel therapeutic strategies therapeutic target hsa-mir-130a Cardiac Fibrosis 29114000 "MicroRNA-130a, a Potential Antifibrotic Target in Cardiac Fibrosis." therapeutic target hsa-mir-145 "Carcinoma, Hepatocellular" 29156696 The interaction between pSmad3C/3L and microRNA-145/21 regulates HCC progression and the switch of pSmad3C/3L may serve as an important target for HCC therapy therapeutic target hsa-mir-29b Glioblastoma 29176935 miR-29b may serve as a putative therapeutic molecule when its expression is restored using a nanoparticle delivery system in GBM therapeutic target hsa-mir-20a Breast Neoplasms 29179464 Therapy directed at uPAR-induced miR-17/20a is a potential option for breast cancer and TNBC therapeutic target hsa-mir-124 Glioblastoma 29185191 MicroRNAs (miRs) are potential therapeutic targets in glioblastoma multiforme (GBM) therapeutic target hsa-mir-21 Keloid 29190966 "inhibition of microRNA-21 induces mitochondrial-mediated apoptosis in keloid fibroblasts, proposing microRNA-21 as a potential therapeutic target in keloid fibroblasts" therapeutic target hsa-mir-126 Pancreatic Adenocarcinoma 29200874 The therapeutic system co-expressing miR-126 and miR-34a mediated by oncolytic adenovirus is a promising system for PAC target therapy therapeutic target hsa-mir-34a Pancreatic Adenocarcinoma 29200874 The therapeutic system co-expressing miR-126 and miR-34a mediated by oncolytic adenovirus is a promising system for PAC target therapy therapeutic target hsa-mir-150 Chronic Obstructive Pulmonary Disease 29205062 Restoration of miR-150 expression may represent a potential therapeutic strategy for CS-related COPD therapeutic target hsa-mir-100 Atherosclerosis 29208678 "Our findings of miR-100 as a potential protective anti-athero-miR suggest that the therapeutic replacement of this microRNA could be a potential strategy for the treatment of chronic inflammatory diseases, such as atherosclerosis, in the future" therapeutic target hsa-mir-21 Atherosclerosis 29228671 "our results demonstrated that metformin improved IRSM by inhibiting miR-21 expression, and that miR-21 may be one of the therapeutic targets for IR" therapeutic target hsa-let-7a Prostate Neoplasms 29236328 the therapeutic potential of Let-7a as an antitumor and antimetastatic manager in prostate cancer and CCR7 may be regarded as a therapeutic target for the prostate cancer treatment therapeutic target hsa-mir-34a Multiple Myeloma 29263373 Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment therapeutic target hsa-mir-1 Myocardial Infarction 29269324 Delivery of microRNA-1 inhibitor by dendrimer-based nanovector: An early targeting therapy for myocardial infarction in mice therapeutic target hsa-mir-204 "Adenocarcinoma, Lung" 29281186 "Clinically, the miR-204/JAK2/STAT3 signaling pathway is a putative therapeutic target in lung adenocarcinoma" therapeutic target hsa-mir-155 Neoplasms [unspecific] 29282605 miR-155 in cancer drug resistance and as target for miRNA-based therapeutics therapeutic target hsa-mir-34a Heart Diseases [unspecific] 29302057 "inhibition of miR-34a activity has differential effects depending on the cell type, thereby warranting the need to eliminate off-target effects when introducing miR-based therapy" therapeutic target hsa-mir-205 "Carcinoma, Thyroid, Anaplastic" 29317480 This may open avenues to exploit miR-205 as an alternative cancer therapeutic strategy in the future therapeutic target hsa-mir-19a Cervical Neoplasms 29332345 "Overall, inhibiting miR-19a significantly improves the sensitivity of SiHa cells to radiotherapy, which could lead to new methods for the treatment of cervical cancer" therapeutic target hsa-let-7 Breast Neoplasms 29336465 the findings identified a biochemical and functional link between Let-7 and endocrine therapy in breast CSCs therapeutic target hsa-mir-21 Glioblastoma 29340361 DP-Cur is an efficient carrier of miR21ASO and the combined delivery of miR21ASO and curcumin may be useful in the development of combination therapy for glioblastoma therapeutic target hsa-mir-221 "Carcinoma, Thyroid" 29351231 These ceRNAs are critical in revealing the secrets behind thyroid cancer progression and may serve as future therapeutic biomarkers therapeutic target hsa-mir-222 "Carcinoma, Thyroid" 29351231 These ceRNAs are critical in revealing the secrets behind thyroid cancer progression and may serve as future therapeutic biomarkers therapeutic target hsa-mir-375 "Carcinoma, Thyroid" 29351231 These ceRNAs are critical in revealing the secrets behind thyroid cancer progression and may serve as future therapeutic biomarkers therapeutic target hsa-mir-155 Arthritis 29354135 "we review the evidence for the pathogenic role of miR-155 in driving aberrant activation of the immune system in rheumatoid arthritis, and its potential as a disease biomarker and therapeutic target" therapeutic target hsa-mir-16 Short Bowel Syndrome 29364022 Modulation of these pathways may represent a new therapeutic option for the management of short bowel syndrome therapeutic target hsa-mir-5338 Prostate Disease 29382326 Study on the inhibition of Mfn1 by plant-derived miR5338 mediating the treatment of BPH with rape bee pollen. therapeutic target hsa-mir-155 Polycystic Ovarian Syndrome 29385860 Serum miRNAs in women affected by hyperandrogenic polycystic ovary syndrome: the potential role of miR-155 as a biomarker for monitoring the estroprogestinic treatment. therapeutic target hsa-mir-200a Colorectal Carcinoma 29388209 The miR200 family has potential for both prognostic and therapeutic management of CRC. therapeutic target hsa-mir-200c Colorectal Carcinoma 29388209 The miR201 family has potential for both prognostic and therapeutic management of CRC. therapeutic target hsa-mir-19a "Carcinoma, Hepatocellular" 29393488 miR?19a may have potential as a novel molecular marker for HCC and Pter may be a promising clinical target with the potential to be developed as a HCC therapy therapeutic target hsa-mir-15a Breast Neoplasms 29394261 modulatingspecific miRNAs may serve as a therapeutic approach for the treatment of breast cancer therapeutic target hsa-let-7b Intestinal Barrier Dysfunction 29402773 Let-7b was identified as a novel diagnosis biomarker or a potential treatment target for preventing intestinal barrier dysfunction therapeutic target hsa-mir-221 Parkinson Disease 29405726 miR-221 may serve as a potential therapeutic target for Parkinson's disease treatment therapeutic target hsa-mir-155 Liver Injury 29420849 maintaining miR-155 expression in inflammatory cells might be a potential strategy to modulate liver injury therapeutic target hsa-mir-145 Hypertension 29434681 miR-145 is a potential target for the treatment of hypertension therapeutic target hsa-mir-1268a Neoplasms [unspecific] 29435930 "Quantum Language of MicroRNA: Application for New Cancer Therapeutic Targets(the top 5 of high DNS were in rmiRNAs, rmiR-4466 in 5¡äETS, rmiR-3656 in 28S, rmiR-1268a and rmiR-1268b in 3¡äETS, and rmiR-6729)" therapeutic target hsa-mir-1268b Neoplasms [unspecific] 29435930 "Quantum Language of MicroRNA: Application for New Cancer Therapeutic Targets(the top 5 of high DNS were in rmiRNAs, rmiR-4466 in 5¡äETS, rmiR-3656 in 28S, rmiR-1268a and rmiR-1268b in 3¡äETS, and rmiR-6729)" therapeutic target hsa-mir-3656 Neoplasms [unspecific] 29435930 "Quantum Language of MicroRNA: Application for New Cancer Therapeutic Targets(the top 5 of high DNS were in rmiRNAs, rmiR-4466 in 5¡äETS, rmiR-3656 in 28S, rmiR-1268a and rmiR-1268b in 3¡äETS, and rmiR-6729)" therapeutic target hsa-mir-4466 Neoplasms [unspecific] 29435930 "Quantum Language of MicroRNA: Application for New Cancer Therapeutic Targets(the top 5 of high DNS were in rmiRNAs, rmiR-4466 in 5¡äETS, rmiR-3656 in 28S, rmiR-1268a and rmiR-1268b in 3¡äETS, and rmiR-6729)" therapeutic target hsa-mir-6729 Neoplasms [unspecific] 29435930 "Quantum Language of MicroRNA: Application for New Cancer Therapeutic Targets(the top 5 of high DNS were in rmiRNAs, rmiR-4466 in 5¡äETS, rmiR-3656 in 28S, rmiR-1268a and rmiR-1268b in 3¡äETS, and rmiR-6729)" therapeutic target hsa-mir-10a Atherosclerosis 29459264 EC miR-10a induction by RAR¦Á/RXR¦Á-specific agonists is a potential hemodynamics-based strategy for atherosclerosis treatment therapeutic target hsa-mir-17 "Carcinoma, Hepatocellular" 29464015 "Hence, anti-miR-17 is an effective therapy for MYC-driven HCC" therapeutic target hsa-mir-22 Heart Failure 29486470 "Our findings demonstrate that miR-22 accelerates cardiac fibrosis through the miR-22-Cav3-PKC¦Å pathway, which, therefore, may represent a new therapeutic target for treatment of excessive fibrosis-associated cardiac diseases" therapeutic target hsa-mir-146a Ischemia-Reperfusion Injury 29505740 our findings demonstrate that the elevation of miR-146a may be one of the compensatory responses after the cerebral I/R injury and suggest miR-146a as a potential therapeutic target for cerebral I/R injury therapeutic target hsa-mir-134 Diabetic Nephropathy 29532746 MiR-150 and miR-134 may be essential microRNAs in the treatment of MSCs for DN therapeutic target hsa-mir-150 Diabetic Nephropathy 29532746 MiR-150 and miR-134 may be essential microRNAs in the treatment of MSCs for DN therapeutic target hsa-mir-155 "Carcinoma, Renal Cell, Clear-Cell" 29534467 Our results further support a role for miR-155 as a promising cancer classifier and potentially as a therapeutic target in ccRCC that merits further investigation therapeutic target hsa-mir-192 "Carcinoma, Bladder" 29536411 miR-192-5p might serve as a promising target in bladder cancer diagnosis and therapy therapeutic target hsa-mir-125b Hepatitis C Virus Infection 29541414 This study elucidates a novel pathway for miR-125b in the pathogenesis of chronic HCV infection and suggests it as a possible target for treating HCV infection therapeutic target hsa-let-7d Alzheimer Disease 29543360 The potential functions of these miRNAs as diagnostic and therapeutic targets of the AD were revealed by this study therapeutic target hsa-let-7g Alzheimer Disease 29543360 The potential functions of these miRNAs as diagnostic and therapeutic targets of the AD were revealed by this study therapeutic target hsa-mir-101 Alzheimer Disease 29543360 The potential functions of these miRNAs as diagnostic and therapeutic targets of the AD were revealed by this study therapeutic target hsa-mir-125b Alzheimer Disease 29543360 The potential functions of these miRNAs as diagnostic and therapeutic targets of the AD were revealed by this study therapeutic target hsa-mir-155 Alzheimer Disease 29543360 The potential functions of these miRNAs as diagnostic and therapeutic targets of the AD were revealed by this study therapeutic target hsa-mir-15b Alzheimer Disease 29543360 The potential functions of these miRNAs as diagnostic and therapeutic targets of the AD were revealed by this study therapeutic target hsa-mir-191 Alzheimer Disease 29543360 The potential functions of these miRNAs as diagnostic and therapeutic targets of the AD were revealed by this study therapeutic target hsa-mir-26b Alzheimer Disease 29543360 The potential functions of these miRNAs as diagnostic and therapeutic targets of the AD were revealed by this study therapeutic target hsa-mir-29b Alzheimer Disease 29543360 The potential functions of these miRNAs as diagnostic and therapeutic targets of the AD were revealed by this study therapeutic target hsa-mir-342 Alzheimer Disease 29543360 The potential functions of these miRNAs as diagnostic and therapeutic targets of the AD were revealed by this study therapeutic target hsa-mir-34a Alzheimer Disease 29543360 The potential functions of these miRNAs as diagnostic and therapeutic targets of the AD were revealed by this study therapeutic target hsa-mir-9 Alzheimer Disease 29543360 The potential functions of these miRNAs as diagnostic and therapeutic targets of the AD were revealed by this study therapeutic target hsa-mir-7 Colorectal Carcinoma 29549306 therapeutic targeting of the c-Myb/circHIPK3/miR-7 axis may be a promising treatment approach for CRC patients therapeutic target hsa-mir-21 Breast Neoplasms 29567152 chemically modified miRNA-21 inhibitor based on gold nanoparticles would be as a promising diagnostic and therapeutic platform for breast cancer clinically therapeutic target hsa-mir-21 "Squamous Cell Carcinoma, Esophageal" 29568234 MiR-21 is a potential novel target for developing specific treatment interventions in ESCC in future therapeutic target hsa-mir-186 Melanoma 29578151 "miR-186 exhibit an inhibitory effect on CMM cell proliferation, migration, and invasion; thus, may serve as a potential therapeutic target for human CMM intervention" therapeutic target hsa-mir-200c Chronic Hepatitis B 29593314 an HBV-pSTAT3-SALL4-miR-200c axis regulates PD-L1. Therapeutic strategies to influence this axis might reverse virus-induced immune exhaustion therapeutic target hsa-mir-124 Neoplasms [unspecific] 29602831 "This novel ncRNA bioengineering platform can be easily adapted to produce various ncRNA molecules, and biologic ncRNAs hold the promise as new cancer therapeutics" therapeutic target hsa-mir-34a Neoplasms [unspecific] 29602831 "This novel ncRNA bioengineering platform can be easily adapted to produce various ncRNA molecules, and biologic ncRNAs hold the promise as new cancer therapeutics" therapeutic target hsa-mir-21 Inflammation 29620442 It may provide a novel therapeutic strategy to regulate the odontoblast differentiation of DPSCs therapeutic target hsa-mir-21 Endometriosis 29625267 Identification of small-molecule ligands that bind to MiR-21 as potential therapeutics for endometriosis by screening ZINC database and in-vitro assays. therapeutic target hsa-mir-143 Endometrial Neoplasms 29661100 these miRNAs are potential candidates for the diagnosis of endometrial cancer and therapeutic targets therapeutic target hsa-mir-145 Endometrial Neoplasms 29661100 these miRNAs are potential candidates for the diagnosis of endometrial cancer and therapeutic targets therapeutic target hsa-mir-378 Bone Disease [unspecific] 29686962 "miR378 was an ideal target to osteogenesis-angiogenesis coupling for bone regeneration, which provides a potential tool for the gene therapy of bone regeneration." therapeutic target hsa-mir-139 Ovarian Neoplasms 29719173 miR-139-5p overexpression might be a future therapeutic strategy for OC. therapeutic target hsa-mir-145 Urinary Bladder Cancer 29723992 "MicroRNAs in Smoking-Related Carcinogenesis: Biomarkers, Functions, and Therapy." therapeutic target hsa-mir-224 "Carcinoma, Lung, Non-Small-Cell" 29723992 "MicroRNAs in Smoking-Related Carcinogenesis: Biomarkers, Functions, and Therapy." therapeutic target hsa-mir-21 Seizures 29751355 The miR-21-5p/PTEN/mTOR axis may be a potential target for preventing and treating seizures and epileptic damage therapeutic target hsa-mir-204 "Leukemia, Myeloid, Acute" 29764561 MiR-204 acts as a potential therapeutic target in acute myeloid leukemia by increasing BIRC6-mediated apoptosis. therapeutic target hsa-mir-107 Burns 29802017 "Expression of junctional proteins such as claudin-1, loricrin, filaggrin, ZO-1, and ZO-2 were significantly upregulated following TLN¦Ê/anti-miR-107 treatment" therapeutic target hsa-mir-145 "Carcinoma, Hepatocellular" 29805683 "certain miRNAs (including miR-96, miR-145 and miR-183) and mRNAs may be therapeutic targets of ribavirin in hepatocellular carcinoma." therapeutic target hsa-mir-183 "Carcinoma, Hepatocellular" 29805683 "certain miRNAs (including miR-96, miR-145 and miR-183) and mRNAs may be therapeutic targets of ribavirin in hepatocellular carcinoma." therapeutic target hsa-mir-96 "Carcinoma, Hepatocellular" 29805683 "certain miRNAs (including miR-96, miR-145 and miR-183) and mRNAs may be therapeutic targets of ribavirin in hepatocellular carcinoma." therapeutic target hsa-mir-106a Prostate Neoplasms 29845714 "Our research provides the first report of miR-106a and LITAF in prostate cancer radiation resistance and high-grade disease, and presents a viable therapeutic strategy that may ultimately improve patient outcomes" therapeutic target hsa-mir-543 Periodontitis 29851072 miR-543 may be a potential therapy for bone loss in periodontitis therapeutic target hsa-mir-145 Prostate Neoplasms 29858716 Treating metastatic prostate cancer with microRNA-145. therapeutic target hsa-mir-335 Sepsis 29866515 upregulation of miR-335-5p is therapeutic strategy for sepsis therapeutic target hsa-mir-1297 Melanoma 29873263 seed-targeted anti-miR-1297 might serve as a new tactic for miR-1297-based therapies therapeutic target hsa-mir-9 Gastric Neoplasms 29879907 Targeting miR-9 in gastric cancer cells using locked nucleic acid oligonucleotides. therapeutic target hsa-mir-143 Neoplasms [unspecific] 29929447 Hsa-miR-143-3p and hsa-miR-193b-3p were found to be up-regulated by the use of different non-viral vectors and can thus serve as potential targets of non-viral cancer gene therapy therapeutic target hsa-mir-193b Neoplasms [unspecific] 29929447 Hsa-miR-143-3p and hsa-miR-193b-3p were found to be up-regulated by the use of different non-viral vectors and can thus serve as potential targets of non-viral cancer gene therapy therapeutic target hsa-mir-146a Autism Spectrum Disorder 29951184 miR-146a may be new therapeutic targets and strategies therapeutic target hsa-mir-214 Human Papilloma Virus Infection 29952653 MiR-214-3p can possibly serve as a valuable biomarker and a therapeutic target for SNIP therapeutic target hsa-mir-29a Liver Fibrosis 29954104 "This review focuses on the evolving view of the molecular mechanisms by which HSC activation by miR-29a signaling may moderate the profibrogenic phenotype of these cells, thus supporting the use of miR-29a agonists as a potential therapy for treating liver fibrosis in the future" therapeutic target hsa-mir-21 Hypertension 29973661 The potential role of miR-21 as a new target for predicting and treating hypertension is also explored therapeutic target hsa-mir-21 "Carcinoma, Breast" 29981261 Dynamic microRNA activity identifies therapeutic targets in trastuzumab-resistant HER2+ breast cancer. therapeutic target hsa-mir-17 Multiple Myeloma 29997223 "Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92." therapeutic target hsa-mir-18 Multiple Myeloma 29997223 "Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92." therapeutic target hsa-mir-19a Multiple Myeloma 29997223 "Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92." therapeutic target hsa-mir-19b-1 Multiple Myeloma 29997223 "Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92." therapeutic target hsa-mir-20a Multiple Myeloma 29997223 "Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92." therapeutic target hsa-mir-92-1 Multiple Myeloma 29997223 "Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92." therapeutic target hsa-mir-155 Mesial Temporal Lobe Epilepsy 30006293 regulation of the miR-155/TNF-¦Á axis may be a new therapeutic target for TLE therapeutic target hsa-mir-135a Glioma 30015885 "miR?135A/B, and the target FOXO1, may be potential therapy targets for glioma treatment" therapeutic target hsa-mir-135b Glioma 30015885 "miR?135A/B, and the target FOXO1, may be potential therapy targets for glioma treatment" therapeutic target hsa-mir-338 Bone Disease [unspecific] 30029590 "new miRNAs like MIR-338 and MIR-376A were identified, which may serve as potential therapeutic targets for the effective treatment of cerebral ischemic injury" therapeutic target hsa-mir-367a Bone Disease [unspecific] 30029590 "new miRNAs like MIR-338 and MIR-376A were identified, which may serve as potential therapeutic targets for the effective treatment of cerebral ischemic injury" therapeutic target hsa-mir-122 Hepatitis C Virus Infection 30038017 "MicroRNA-122 (miR-122), a target of current phase II anti-HCV drugs, is known to protect HCV transcripts against XRNs" therapeutic target hsa-mir-34a "Carcinoma, Breast, Triple Negative" 30072748 MicroRNA in diagnosis and therapy monitoring of early-stage triple-negative breast cancer. therapeutic target hsa-mir-1290 Colon Neoplasms 30073936 "particularly hsa-miR-424-5p, hsa-miR-96-5p, hsa-miR-1290, hsa-miR-224, hsa-miR-133a and has-miR-363-3p present possible targets for colon cancer" therapeutic target hsa-mir-133a Colon Neoplasms 30073936 "particularly hsa-miR-424-5p, hsa-miR-96-5p, hsa-miR-1290, hsa-miR-224, hsa-miR-133a and has-miR-363-3p present possible targets for colon cancer" therapeutic target hsa-mir-224 Colon Neoplasms 30073936 "particularly hsa-miR-424-5p, hsa-miR-96-5p, hsa-miR-1290, hsa-miR-224, hsa-miR-133a and has-miR-363-3p present possible targets for colon cancer" therapeutic target hsa-mir-363 Colon Neoplasms 30073936 "particularly hsa-miR-424-5p, hsa-miR-96-5p, hsa-miR-1290, hsa-miR-224, hsa-miR-133a and has-miR-363-3p present possible targets for colon cancer" therapeutic target hsa-mir-424 Colon Neoplasms 30073936 "particularly hsa-miR-424-5p, hsa-miR-96-5p, hsa-miR-1290, hsa-miR-224, hsa-miR-133a and has-miR-363-3p present possible targets for colon cancer" therapeutic target hsa-mir-96 Colon Neoplasms 30073936 "particularly hsa-miR-424-5p, hsa-miR-96-5p, hsa-miR-1290, hsa-miR-224, hsa-miR-133a and has-miR-363-3p present possible targets for colon cancer" therapeutic target hsa-mir-26a "Carcinoma, Hepatocellular" 30076741 Lower expression of tumor microRNA-26a is associated with higher recurrence in patients with hepatocellular carcinoma undergoing surgical treatment. therapeutic target hsa-mir-326 Autoimmune Diseases [unspecific] 30078204 "The MicroRNA-326: Autoimmune diseases, diagnostic biomarker, and therapeutic target." therapeutic target hsa-mir-141 "Carcinoma, Hepatocellular" 30083268 Tumor-suppressing miR-141 gene complex-loaded tissue-adhesive glue for the locoregional treatment of hepatocellular carcinoma. therapeutic target hsa-mir-33 Atherosclerosis 30092598 miR-33 represents a novel target for the treatment of atherosclerosis therapeutic target hsa-mir-187 Gastric Neoplasms 30112051 miR-187 may be a potential biomarker and therapeutic target in GC therapeutic target hsa-mir-143 Neoplasms [unspecific] 30150287 Our findings will encourage the development of new strategies targeting miR-143 in both cancer cells and T cells therapeutic target hsa-mir-21 Primary Aldosteronism 30153065 miR-21 supplementation may be a novel therapeutic approach to abolish or mitigate excess aldosterone-mediated cardiovascular deleterious effects in primary aldosteronism therapeutic target hsa-mir-30a Neoplasms [unspecific] 30158978 MiR-30a: A Novel Biomarker and Potential Therapeutic Target for Cancer. therapeutic target hsa-mir-10a "Carcinoma, Breast" 30160115 Anti-breast-Cancer Activity Exerted by ¦Â-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway. therapeutic target hsa-mir-223 Wound Healing 30171089 Targeting miR-223 in neutrophils enhances the?clearance of Staphylococcus aureus in infected?wounds. therapeutic target hsa-mir-636 Hepatitis C Virus Infection 30174796 miR-636 might be one of the essential targetable molecules in HCV patients who undergo DAA therapy and still suffer from a sustained HCV infection therapeutic target hsa-mir-383 Heart Failure 30206318 Multipoint targeting of TGF-¦Â/Wnt transactivation circuit with microRNA 384-5p for cardiac fibrosis. therapeutic target hsa-mir-126 Vascular Injuries 30213595 Dicer promotes endothelial recovery and limits lesion formation after vascular injury through miR-126-5p. therapeutic target hsa-mir-210 Cholangiocarcinoma 30214622 Cholangiocarcinoma therapy with nanoparticles that combine downregulation of MicroRNA-210 with inhibition of cancer cell invasiveness. therapeutic target hsa-mir-150 Rheumatoid Arthritis 30224512 Therapeutic Potential of Mesenchymal Cell-Derived miRNA-150-5p-Expressing Exosomes in Rheumatoid Arthritis Mediated by the Modulation of MMP14 and VEGF. therapeutic target hsa-mir-423 "Adenocarcinoma, Lung" 30224667 MiR-423-5p has the potential to be a marker of BM and/or a therapeutic target in LAD therapeutic target hsa-mir-126 "Carcinoma, Hepatocellular" 30268144 Targeting miR-494-3p and miR-126-3p may provide effective and promising approaches to suppress invasion and metastasis of HCC therapeutic target hsa-mir-494 "Carcinoma, Hepatocellular" 30268144 Targeting miR-494-3p and miR-126-3p may provide effective and promising approaches to suppress invasion and metastasis of HCC therapeutic target hsa-mir-17 Rectal Neoplasms 30277504 Expression profile of miR-17/92 cluster is predictive of treatment response in rectal cancer. therapeutic target hsa-mir-18 Rectal Neoplasms 30277504 Expression profile of miR-17/92 cluster is predictive of treatment response in rectal cancer. therapeutic target hsa-mir-19a Rectal Neoplasms 30277504 Expression profile of miR-17/92 cluster is predictive of treatment response in rectal cancer. therapeutic target hsa-mir-19b-1 Rectal Neoplasms 30277504 Expression profile of miR-17/92 cluster is predictive of treatment response in rectal cancer. therapeutic target hsa-mir-20a Rectal Neoplasms 30277504 Expression profile of miR-17/92 cluster is predictive of treatment response in rectal cancer. therapeutic target hsa-mir-92-1 Rectal Neoplasms 30277504 Expression profile of miR-17/92 cluster is predictive of treatment response in rectal cancer. therapeutic target hsa-mir-425 "Leukemia, Myeloid, Acute" 30285885 MiR-425 expression profiling in acute myeloid leukemia might guide the treatment choice between allogeneic transplantation and chemotherapy. therapeutic target hsa-mir-221 "Fatty Liver, Non-Alcoholic" 30316865 Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice. therapeutic target hsa-mir-222 "Fatty Liver, Non-Alcoholic" 30316865 Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice. therapeutic target hsa-mir-155 Neoplasms [unspecific] 30319757 "a DNA nanotube structure that carries functional DNA segments (single-stranded, duplex and hairpin forms) was designed and synthesized to capture two well-known overexpressed miRNAs, miR-21 and miR-155" therapeutic target hsa-mir-21 Neoplasms [unspecific] 30319757 "a DNA nanotube structure that carries functional DNA segments (single-stranded, duplex and hairpin forms) was designed and synthesized to capture two well-known overexpressed miRNAs, miR-21 and miR-155" therapeutic target hsa-mir-20a "Leukemia, T-Cell" 30336537 miR-20a may act as a tumor suppressor in CD4+ T cells and also has a potential therapeutic in these kinds of cancers therapeutic target hsa-mir-34c "Carcinoma, Lung, Non-Small-Cell" 30340138 the GL21.T/miR-34c chimera exerts dual inhibition of AXL at functional and transcriptional levels and represents a novel therapeutic tool for the treatment of NSCLC therapeutic target hsa-mir-200b "Carcinoma, Breast" 30342533 The miR-200b presents a great potential for the future advancements in the diagnostic/prognostic and therapeutic approach of TNBC therapeutic target hsa-mir-647 "Carcinoma, Lung, Non-Small-Cell" 30349310 MicroRNA-647 promotes the therapeutic effectiveness of argon-helium cryoablation and inhibits cell proliferation through targeting TRAF2 via the NF-¦ÊB signaling pathway in non-small cell lung cancer. therapeutic target hsa-mir-33b Atherosclerosis 30354203 miR-33b is a promising target for treating atherosclerosis therapeutic target hsa-mir-1247 Prostate Neoplasms 30378132 our data highlight miR-1247 as a potential target for molecular therapies aimed to block the progression and diffusion of PCa therapeutic target hsa-mir-20b Tuberculosis 30378171 miR-20b-5p and exosomes as the potential therapeutic targets of TB transcription factor target hsa-mir-451 "Leukemia, Myeloid, Chronic" 27825294 Downregulation of miR-451 in Tunisian chronic myeloid leukemia patients: potential implication in imatinib resistance. transcription factor target hsa-mir-20a Retinoblastoma 17135249 "Altogether, these results suggest that the autoregulation between E2F1-3 and miR-20a is important for preventing an abnormal accumulation of E2F1-3 and may play a role in the regulation of cellular proliferation and apoptosis." transcription factor target hsa-mir-21 Multiple Myeloma 17496199 Ectopically raising miR-21 expression in myeloma cells in the absence of IL-6 significantly reduced their apoptosis levels. These data provide strong evidence that miR-21 induction contributes to the oncogenic potential of Stat3. transcription factor target hsa-mir-34a Neoplasms [unspecific] 17656095 "Taken together, the data suggest the miRNA34s might be key effectors of p53 tumor-suppressor function, and their inactivation might contribute to certain cancers." transcription factor target hsa-mir-34b Neoplasms [unspecific] 17656095 "Taken together, the data suggest the miRNA34s might be key effectors of p53 tumor-suppressor function, and their inactivation might contribute to certain cancers." transcription factor target hsa-mir-34c Neoplasms [unspecific] 17656095 "Taken together, the data suggest the miRNA34s might be key effectors of p53 tumor-suppressor function, and their inactivation might contribute to certain cancers." transcription factor target hsa-mir-34b "Carcinoma, Ovarian" 17823410 "Importantly, miR-34b and miR-34c cooperate in suppressing proliferation and soft-agar colony formation of neoplastic epithelial ovarian cells, in agreement with the partially overlapping spectrum of their predicted targets." transcription factor target hsa-mir-34c "Carcinoma, Ovarian" 17823410 "Importantly, miR-34b and miR-34c cooperate in suppressing proliferation and soft-agar colony formation of neoplastic epithelial ovarian cells, in agreement with the partially overlapping spectrum of their predicted targets." transcription factor target hsa-mir-106a Neuroblastoma 17943719 The miR-17-92 polycistron also acts as an oncogene in haematopoietic progenitor cells. We show here that miR-221 is also induced by MYCN in neuroblastoma. transcription factor target hsa-mir-17 Neuroblastoma 17943719 The miR-17-92 polycistron also acts as an oncogene in haematopoietic progenitor cells. We show here that miR-221 is also induced by MYCN in neuroblastoma. transcription factor target hsa-mir-18 Neuroblastoma 17943719 The miR-17-92 polycistron also acts as an oncogene in haematopoietic progenitor cells. We show here that miR-221 is also induced by MYCN in neuroblastoma. transcription factor target hsa-mir-19a Neuroblastoma 17943719 The miR-17-92 polycistron also acts as an oncogene in haematopoietic progenitor cells. We show here that miR-221 is also induced by MYCN in neuroblastoma. transcription factor target hsa-mir-19b-1 Neuroblastoma 17943719 The miR-17-92 polycistron also acts as an oncogene in haematopoietic progenitor cells. We show here that miR-221 is also induced by MYCN in neuroblastoma. transcription factor target hsa-mir-20a Neuroblastoma 17943719 The miR-17-92 polycistron also acts as an oncogene in haematopoietic progenitor cells. We show here that miR-221 is also induced by MYCN in neuroblastoma. transcription factor target hsa-mir-221 Neuroblastoma 17943719 The miR-17-92 polycistron also acts as an oncogene in haematopoietic progenitor cells. We show here that miR-221 is also induced by MYCN in neuroblastoma. transcription factor target hsa-mir-92-1 Neuroblastoma 17943719 The miR-17-92 polycistron also acts as an oncogene in haematopoietic progenitor cells. We show here that miR-221 is also induced by MYCN in neuroblastoma. transcription factor target hsa-mir-125b Prostate Neoplasms 18056640 "Our results suggest that miR-125b acts as an oncogene, contributing to the pathogenesis of CaP." transcription factor target hsa-mir-184 Autism Spectrum Disorder 18203756 The restricted release of MeCP2 from the paternal allele results in paternal allele-specific expression of miR-184. Our finding provides a clue to the link between the microRNA and DNA methylation pathways. transcription factor target hsa-mir-21 Neoplasms [unspecific] 18384814 "Since exogenous miR-21 expression moderately induced endogenous miR-21, an evolutionarily conserved double-negative feedback regulation would be operating as a mechanism to sustain miR-21 expression." transcription factor target hsa-mir-23a "Carcinoma, Hepatocellular" 18508316 We also explore that miR-23a approximately 27a approximately 24 can function as an antiapoptotic and proliferation-promoting factor in liver cancer cells. transcription factor target hsa-mir-24 "Carcinoma, Hepatocellular" 18508316 We also explore that miR-23a approximately 27a approximately 24 can function as an antiapoptotic and proliferation-promoting factor in liver cancer cells. transcription factor target hsa-mir-27a "Carcinoma, Hepatocellular" 18508316 We also explore that miR-23a approximately 27a approximately 24 can function as an antiapoptotic and proliferation-promoting factor in liver cancer cells. transcription factor target hsa-mir-146a Leukemia 18568019 "In leukaemic cell lines PLZF overexpression downmodulated miR-146a and upregulated CXCR4 protein, whereas PLZF knockdown induced the opposite effects." transcription factor target hsa-mir-34a "Leukemia, Lymphocytic, Chronic, B-Cell" 18818704 17p13/TP53 deletion in B-CLL patients is associated with microRNA-34a downregulation. transcription factor target hsa-mir-141 Neoplasms [unspecific] 18829540 These findings establish a double-negative feedback loop controlling ZEB1-SIP1 and miR-200 family expression that regulates cellular phenotype and has direct relevance to the role of these factors in tumor progression. transcription factor target hsa-mir-200a Neoplasms [unspecific] 18829540 These findings establish a double-negative feedback loop controlling ZEB1-SIP1 and miR-200 family expression that regulates cellular phenotype and has direct relevance to the role of these factors in tumor progression. transcription factor target hsa-mir-200b Neoplasms [unspecific] 18829540 These findings establish a double-negative feedback loop controlling ZEB1-SIP1 and miR-200 family expression that regulates cellular phenotype and has direct relevance to the role of these factors in tumor progression. transcription factor target hsa-mir-200c Neoplasms [unspecific] 18829540 These findings establish a double-negative feedback loop controlling ZEB1-SIP1 and miR-200 family expression that regulates cellular phenotype and has direct relevance to the role of these factors in tumor progression. transcription factor target hsa-mir-429 Neoplasms [unspecific] 18829540 These findings establish a double-negative feedback loop controlling ZEB1-SIP1 and miR-200 family expression that regulates cellular phenotype and has direct relevance to the role of these factors in tumor progression. transcription factor target hsa-mir-7 Breast Neoplasms 18922890 "Finally, we show that miR-7 introduction inhibits the motility, invasiveness, anchorage-independent growth, and tumorigenic potential of highly invasive breast cancer cells." transcription factor target hsa-mir-155 Inflammation 18940871 "Finally, we demonstrate that LMP1-mediated activation of miR-155 in an EBV-negative background correlates with reduction of protein PU.1, which is a possible miR target." transcription factor target hsa-mir-146a Neoplasms [unspecific] 19021527 "In the present article, we review the evidence for a role of miR-146a in innate immunity and cancer and assess whether changes in miR-146a might link these two biological responses." transcription factor target hsa-mir-17 Neoplasms [unspecific] 19066217 "Using the concept and model prediction of a ""cancer zone,"" the oncogenic and tumor suppressor properties of miR-17-92 is demonstrated to parallel the same properties of E2F and Myc." transcription factor target hsa-mir-18 Neoplasms [unspecific] 19066217 "Using the concept and model prediction of a ""cancer zone,"" the oncogenic and tumor suppressor properties of miR-17-92 is demonstrated to parallel the same properties of E2F and Myc." transcription factor target hsa-mir-19a Neoplasms [unspecific] 19066217 "Using the concept and model prediction of a ""cancer zone,"" the oncogenic and tumor suppressor properties of miR-17-92 is demonstrated to parallel the same properties of E2F and Myc." transcription factor target hsa-mir-19b-1 Neoplasms [unspecific] 19066217 "Using the concept and model prediction of a ""cancer zone,"" the oncogenic and tumor suppressor properties of miR-17-92 is demonstrated to parallel the same properties of E2F and Myc." transcription factor target hsa-mir-20a Neoplasms [unspecific] 19066217 "Using the concept and model prediction of a ""cancer zone,"" the oncogenic and tumor suppressor properties of miR-17-92 is demonstrated to parallel the same properties of E2F and Myc." transcription factor target hsa-mir-92-1 Neoplasms [unspecific] 19066217 "Using the concept and model prediction of a ""cancer zone,"" the oncogenic and tumor suppressor properties of miR-17-92 is demonstrated to parallel the same properties of E2F and Myc." transcription factor target hsa-mir-192 Colon Neoplasms 19074875 "Hence, miR-192 and miR-215 can act as effectors as well as regulators of p53; they seem to suppress cancerogenesis through p21 accumulation and cell cycle arrest." transcription factor target hsa-mir-215 Colon Neoplasms 19074875 "Hence, miR-192 and miR-215 can act as effectors as well as regulators of p53; they seem to suppress cancerogenesis through p21 accumulation and cell cycle arrest." transcription factor target hsa-mir-34a Neoplasms [unspecific] 19074875 "Accordingly, the tumor suppressor p53 up-regulates miR-34a, a microRNA that contributes to apoptosis and acute senescence. " transcription factor target hsa-mir-1 Cardiomegaly 19933931 Our results reveal a critical role of miR-1 in mediating the effects of the IGF-1 pathway and demonstrate a feedback loop between miR-1 expression and the IGF-1 signal transduction cascade. transcription factor target hsa-mir-183 "Carcinoma, Rectal" 19935649 "Moreover, miR-200c, miR-203 and miR-183 cooperate to suppress expression of stem cell factors in cancer cells and mouse embryonic stem (ES) cells, as demonstrated for the polycomb repressor Bmi1." transcription factor target hsa-mir-200c "Carcinoma, Rectal" 19935649 "Moreover, miR-200c, miR-203 and miR-183 cooperate to suppress expression of stem cell factors in cancer cells and mouse embryonic stem (ES) cells, as demonstrated for the polycomb repressor Bmi1." transcription factor target hsa-mir-203 "Carcinoma, Rectal" 19935649 "Moreover, miR-200c, miR-203 and miR-183 cooperate to suppress expression of stem cell factors in cancer cells and mouse embryonic stem (ES) cells, as demonstrated for the polycomb repressor Bmi1." transcription factor target hsa-mir-15a Myeloproliferative Neoplasms 20008792 "STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease." transcription factor target hsa-mir-15b Myeloproliferative Neoplasms 20008792 "STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease." transcription factor target hsa-mir-16 Myeloproliferative Neoplasms 20008792 "STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease." transcription factor target hsa-mir-17 "Lymphoma, B-Cell" 20008931 The miR-17 approximately 92 cluster is frequently amplified or overexpressed in human cancers and has emerged as the prototypical oncogenic polycistron microRNA (miRNA) transcription factor target hsa-mir-18 "Lymphoma, B-Cell" 20008931 The miR-17 approximately 93 cluster is frequently amplified or overexpressed in human cancers and has emerged as the prototypical oncogenic polycistron microRNA (miRNA) transcription factor target hsa-mir-19a "Lymphoma, B-Cell" 20008931 The miR-17 approximately 94 cluster is frequently amplified or overexpressed in human cancers and has emerged as the prototypical oncogenic polycistron microRNA (miRNA) transcription factor target hsa-mir-19b-1 "Lymphoma, B-Cell" 20008931 The miR-17 approximately 95 cluster is frequently amplified or overexpressed in human cancers and has emerged as the prototypical oncogenic polycistron microRNA (miRNA) transcription factor target hsa-mir-20a "Lymphoma, B-Cell" 20008931 The miR-17 approximately 96 cluster is frequently amplified or overexpressed in human cancers and has emerged as the prototypical oncogenic polycistron microRNA (miRNA) transcription factor target hsa-mir-92-1 "Lymphoma, B-Cell" 20008931 The miR-17 approximately 96 cluster is frequently amplified or overexpressed in human cancers and has emerged as the prototypical oncogenic polycistron microRNA (miRNA) transcription factor target hsa-mir-24 Vascular Disease [unspecific] 20019669 Inhibition of miR-24 by antisense oligonuclotides abrogates the downregulation of Trb3 as well as pro-synthetic activity of the PDGF-signalling pathway. transcription factor target hsa-mir-223 "Leukemia, Myeloid, Acute" 20029046 "Our study supports a molecular network involving miR-223, C/EBPalpha, and E2F1 as major components of the granulocyte differentiation program, which is deregulated in AML." transcription factor target hsa-mir-141 "Carcinoma, Nasopharyngeal" 20053927 "We propose that miR-141- and tumor-related genes c-MYC, SPLUNC1, BRD3, UBAP1 and PTEN may constitute a gene-miRNA network to contribute to NPC development." transcription factor target hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 20093556 Our findings indicate that miR-21 warrants further investigation as a marker for early detection of PDAC. transcription factor target hsa-mir-21 Gliosis 20130193 We find that the two receptors exert opposing effects on the posttranscriptional regulation of astrocytic microRNA-21. transcription factor target hsa-mir-9 Breast Neoplasms 20173743 "The microRNA miR-9 is induced by Myc in breast cancer cells where it targets the major epithelial adherens junction protein, E-cadherin." transcription factor target hsa-mir-155 "Adenocarcinoma, Gastric" 20209161 "Taken together, our study describes, in the context of an H. pylori infection, a direct link between Foxp3 and miR-155 in human T cells and highlights the significance of cAMP in this miR-155 induction cascade." transcription factor target hsa-mir-126 Vascular Disease [unspecific] 20364122 "We further find that angiogenic sprouting of AA vessels requires a flow-induced genetic pathway in which the mechano-sensitive zinc finger transcription factor klf2a induces expression of an endothelial-specific microRNA, mir-126, to activate Vegf signalling." transcription factor target hsa-mir-34a Acute Kidney Failure 20386864 MicroRNA-34a is induced via p53 during cisplatin nephrotoxicity and contributes to cell survival. transcription factor target hsa-let-7d Idiopathic Pulmonary Fibrosis 20395557 The down-regulation of let-7d in IPF and the profibrotic effects of this down-regulation in vitro and in vivo suggest a key regulatory role for this microRNA in preventing lung fibrosis. transcription factor target hsa-mir-200a Bladder Neoplasms 20473948 "we observe that the mesoderm transcription factor TWIST1 and miR-200 expression are inversely correlated in bladder tumor samples and cell lines. TWIST1 associates directly with the miR-200 and miR-205 promoters, and may act as a repressor of miR-200 and miR-205 expression." transcription factor target hsa-mir-200b Bladder Neoplasms 20473948 "we observe that the mesoderm transcription factor TWIST1 and miR-200 expression are inversely correlated in bladder tumor samples and cell lines. TWIST1 associates directly with the miR-200 and miR-205 promoters, and may act as a repressor of miR-200 and miR-205 expression." transcription factor target hsa-mir-200c Bladder Neoplasms 20473948 "we observe that the mesoderm transcription factor TWIST1 and miR-200 expression are inversely correlated in bladder tumor samples and cell lines. TWIST1 associates directly with the miR-200 and miR-205 promoters, and may act as a repressor of miR-200 and miR-205 expression." transcription factor target hsa-mir-205 Bladder Neoplasms 20473948 "we observe that the mesoderm transcription factor TWIST1 and miR-200 expression are inversely correlated in bladder tumor samples and cell lines. TWIST1 associates directly with the miR-200 and miR-205 promoters, and may act as a repressor of miR-200 and miR-205 expression." transcription factor target hsa-mir-22 Neoplasms [unspecific] 20523723 Our results suggest that miR-22 acts to fine-tune the dynamics of PTEN/AKT/FoxO1 pathway. transcription factor target hsa-mir-107 Neoplasms [unspecific] 20833636 p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins. transcription factor target hsa-mir-1 "Leukemia, Myeloid, Acute" 20842122 Our data showed that EVI1 controls proliferation in AML through modulation of miR-1-2. This study contributes to further understand the transcriptional networks involving transcription factors and miRNAs in AML. transcription factor target hsa-mir-106a Neoplasms [unspecific] 20878079 "The miR-17 family, composed of miR-17-5p, miR-20a/b, miR-106a/b and miR-93, has been demonstrated to take part in critical pathways that regulate cellular life and death decisions during normal development and in malignancy." transcription factor target hsa-mir-106b Neoplasms [unspecific] 20878079 "The miR-17 family, composed of miR-17-5p, miR-20a/b, miR-106a/b and miR-93, has been demonstrated to take part in critical pathways that regulate cellular life and death decisions during normal development and in malignancy." transcription factor target hsa-mir-17 Neoplasms [unspecific] 20878079 "The miR-17 family, composed of miR-17-5p, miR-20a/b, miR-106a/b and miR-93, has been demonstrated to take part in critical pathways that regulate cellular life and death decisions during normal development and in malignancy." transcription factor target hsa-mir-20a Neoplasms [unspecific] 20878079 "The miR-17 family, composed of miR-17-5p, miR-20a/b, miR-106a/b and miR-93, has been demonstrated to take part in critical pathways that regulate cellular life and death decisions during normal development and in malignancy." transcription factor target hsa-mir-20b Neoplasms [unspecific] 20878079 "The miR-17 family, composed of miR-17-5p, miR-20a/b, miR-106a/b and miR-93, has been demonstrated to take part in critical pathways that regulate cellular life and death decisions during normal development and in malignancy." transcription factor target hsa-mir-93 Neoplasms [unspecific] 20878079 "The miR-17 family, composed of miR-17-5p, miR-20a/b, miR-106a/b and miR-93, has been demonstrated to take part in critical pathways that regulate cellular life and death decisions during normal development and in malignancy." transcription factor target hsa-mir-322 Myocardial Infarction 20972335 These results suggest that miR-322/424 plays an important physiological role in post-ischemic vascular remodeling and angiogenesis. transcription factor target hsa-mir-424 Myocardial Infarction 20972335 These results suggest that miR-322/424 plays an important physiological role in post-ischemic vascular remodeling and angiogenesis. transcription factor target hsa-mir-16 Gastric Neoplasms 21081469 NF-¦ÊB targets miR-16 and miR-21 in gastric cancer: involvement of prostaglandin E receptors. transcription factor target hsa-mir-21 Gastric Neoplasms 21081469 NF-¦ÊB targets miR-16 and miR-21 in gastric cancer: involvement of prostaglandin E receptors. transcription factor target hsa-mir-143 Pancreatic Neoplasms 21159816 "Additionally, KRAS and RREB1 are targets of miR-143/miR-145, revealing a feed-forward mechanism that potentiates Ras signaling." transcription factor target hsa-mir-145 Pancreatic Neoplasms 21159816 "Additionally, KRAS and RREB1 are targets of miR-143/miR-145, revealing a feed-forward mechanism that potentiates Ras signaling." transcription factor target hsa-mir-499 Myocardial Infarction 21186368 Here we report that modulation of microRNA-499 (miR-499) levels affects apoptosis and the severity of myocardial infarction and cardiac dysfunction induced by ischemia-reperfusion. transcription factor target hsa-mir-200c Breast Neoplasms 21336307 "This study elucidates a role for p53 in regulating EMT-MET (mesenchymal-epithelial transition) and stemness or differentiation plasticity, and reveals a potential therapeutic implication to suppress EMT-associated cancer stem cells through activation of the p53-miR-200c pathway." transcription factor target hsa-mir-193a Squamous Cell Carcinoma 21436470 "The resulting feed-forward circuit involving p63, miR-193a-5p and p73 controls p73 levels, cell viability and DNA damage susceptibility in certain cancers including squamous cell carcinoma." transcription factor target hsa-mir-15a Retinoblastoma 21454377 "In particular, miRs encoded by the miR-15a, miR-16-1 cluster seem to act as tumor suppressors. Here, we evidence that the miR-15a, miR-16-1 cluster and related miR-15b, miR-16-2 cluster comprise miRs regulated by E2F1, a pivotal transcription factor that can induce both proliferation and cell death." transcription factor target hsa-mir-15b Retinoblastoma 21454377 "In particular, miRs encoded by the miR-15a, miR-16-1 cluster seem to act as tumor suppressors. Here, we evidence that the miR-15a, miR-16-1 cluster and related miR-15b, miR-16-2 cluster comprise miRs regulated by E2F1, a pivotal transcription factor that can induce both proliferation and cell death." transcription factor target hsa-mir-16-1 Retinoblastoma 21454377 "In particular, miRs encoded by the miR-15a, miR-16-1 cluster seem to act as tumor suppressors. Here, we evidence that the miR-15a, miR-16-1 cluster and related miR-15b, miR-16-2 cluster comprise miRs regulated by E2F1, a pivotal transcription factor that can induce both proliferation and cell death." transcription factor target hsa-mir-16-2 Retinoblastoma 21454377 "In particular, miRs encoded by the miR-15a, miR-16-1 cluster seem to act as tumor suppressors. Here, we evidence that the miR-15a, miR-16-1 cluster and related miR-15b, miR-16-2 cluster comprise miRs regulated by E2F1, a pivotal transcription factor that can induce both proliferation and cell death." transcription factor target hsa-mir-34a Ovarian Neoplasms 21516127 "MiRIDIAN-based knockdown and induction of miR-34a evidenced a direct regulatory link between miR-34a and E2F3a, and the tumor-suppressive character of miR-34a was documented by its association with improved survival." transcription factor target hsa-mir-193a "Adenocarcinoma, Colon" 21670079 "Finally, expression of miR-193a is inversely correlated with PLAU and K-Ras in human colon adenocarcinomas." transcription factor target hsa-mir-21 "Carcinoma, Colon" 21956205 our findings identify direct transcriptional regulation of miR-21 by TCF4 and suggest a role for miR-21 in cancer cell proliferation and invasion upon activation of ¦Â-catenin/TCF4 signaling. transcription factor target hsa-mir-182 Breast Neoplasms 22086602 We demonstrated that DDX5 regulated a subset of MicroRNAs including miR-21 and miR-182 in basal breast cancer cells. transcription factor target hsa-mir-21 Breast Neoplasms 22086602 We demonstrated that DDX5 regulated a subset of MicroRNAs including miR-21 and miR-182 in basal breast cancer cells. transcription factor target hsa-mir-124 Liver Neoplasms 22153071 "we show that transient inhibition of HNF4¦Á initiates hepatocellular transformation through a microRNA-inflammatory feedback loop circuit consisting of miR-124, IL6R, STAT3, miR-24, and miR-629." transcription factor target hsa-mir-24 Liver Neoplasms 22153071 "we show that transient inhibition of HNF4¦Á initiates hepatocellular transformation through a microRNA-inflammatory feedback loop circuit consisting of miR-124, IL6R, STAT3, miR-24, and miR-629." transcription factor target hsa-mir-629 Liver Neoplasms 22153071 "we show that transient inhibition of HNF4¦Á initiates hepatocellular transformation through a microRNA-inflammatory feedback loop circuit consisting of miR-124, IL6R, STAT3, miR-24, and miR-629." transcription factor target hsa-mir-21 "Squamous Cell Carcinoma, Skin or Unspecific" 22614019 These findings indicate that decreased Grhl3 expression contributes to tumor progression and upregulation of the oncomir miR-21 in squamous cell carcinoma of the skin. transcription factor target hsa-mir-143 Colorectal Carcinoma 22751122 These results establish a complex network of regulation through which the miR-143/145 cluster is able to modulate KRAS signaling in colorectal cancer. transcription factor target hsa-mir-145 Colorectal Carcinoma 22751122 These results establish a complex network of regulation through which the miR-143/145 cluster is able to modulate KRAS signaling in colorectal cancer. transcription factor target hsa-mir-103 Breast Neoplasms 22908280 "Aside from the previously identified miR-200 family, these include the miR-15/16 (miR-16, miR-15b) and miR-103/107 (miR-103, miR-107) families as well as miR-145, miR-335, and miR-128b." transcription factor target hsa-mir-107 Breast Neoplasms 22908280 "Aside from the previously identified miR-200 family, these include the miR-15/16 (miR-16, miR-15b) and miR-103/107 (miR-103, miR-107) families as well as miR-145, miR-335, and miR-128b." transcription factor target hsa-mir-128b Breast Neoplasms 22908280 "Aside from the previously identified miR-200 family, these include the miR-15/16 (miR-16, miR-15b) and miR-103/107 (miR-103, miR-107) families as well as miR-145, miR-335, and miR-128b." transcription factor target hsa-mir-145 Breast Neoplasms 22908280 "Aside from the previously identified miR-200 family, these include the miR-15/16 (miR-16, miR-15b) and miR-103/107 (miR-103, miR-107) families as well as miR-145, miR-335, and miR-128b." transcription factor target hsa-mir-15b Breast Neoplasms 22908280 "Aside from the previously identified miR-200 family, these include the miR-15/16 (miR-16, miR-15b) and miR-103/107 (miR-103, miR-107) families as well as miR-145, miR-335, and miR-128b." transcription factor target hsa-mir-16 Breast Neoplasms 22908280 "Aside from the previously identified miR-200 family, these include the miR-15/16 (miR-16, miR-15b) and miR-103/107 (miR-103, miR-107) families as well as miR-145, miR-335, and miR-128b." transcription factor target hsa-mir-335 Breast Neoplasms 22908280 "Aside from the previously identified miR-200 family, these include the miR-15/16 (miR-16, miR-15b) and miR-103/107 (miR-103, miR-107) families as well as miR-145, miR-335, and miR-128b." transcription factor target hsa-mir-199a Liver Cirrhosis 22942713 This review provides a comprehensive survey of the literature on miR-199a as an example of the complexity of miRNA biology and suggests future directions for miRNA research. transcription factor target hsa-mir-26a Lymphoma 23338972 "Our investigation of the mechanisms underlying the decrease in miR-26a in this lymphoma revealed novel evidence that STAT3, a major downstream substrate of NPM-ALK tyrosine kinase activity,suppresses MIR26A1 gene expression." transcription factor target hsa-mir-205 Breast Neoplasms 23474752 Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer. transcription factor target hsa-mir-26a Lymphoma 23538750 Loss- or gain-of-function approaches revealed that miR-26a functioned as a tumor suppressor miRNA and mediated the combinatorial effects of JQ1 and DZNep. transcription factor target hsa-mir-183 Neuroblastoma 23625969 MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma. transcription factor target hsa-mir-155 "Leukemia, Myeloid, Acute" 24263100 "The silencing of Ago2 impairs the D3-dependent miR-17-5p/20a/106a, miR-125b and miR-155 downregulation, the accumulation of their translational targets AML1, VDR and C/EBPβ and monocytic cell differentiation." transcription factor target hsa-mir-17 "Leukemia, Myeloid, Acute" 24263100 "The silencing of Ago2 impairs the D3-dependent miR-17-5p/20a/106a, miR-125b and miR-155 downregulation, the accumulation of their translational targets AML1, VDR and C/EBPβ and monocytic cell differentiation." transcription factor target hsa-mir-17 Toxoplasma gondii Infection 24341525 "We demonstrated that miR-30c-1, miR-125b-2, miR-23b-27b-24-1 and miR-17 ~â€?2 cluster genes were transactivated through promoter binding of the STAT3 following T. gondii infection." transcription factor target hsa-mir-126 Myocardial Infarction 25200057 Exosomes purified from endothelial cells overexpressing HIF1 had higher contents of miR-126 and miR-210. transcription factor target hsa-mir-98 Atherosclerosis 25623956 Coculturing ECs with sSMCs under static condition causes initial increases of 4 anti-inflammatory miRs (146a/708/451/98) in ECs followed by decreases below basal levels at 7 days; transcription factor target hsa-mir-182 Colorectal Carcinoma 25755709 Fentanyl also downregulated the expression of β-catenin and miR-182 in both xenograft tumors and HCT116 cells transcription factor target hsa-mir-146a Inflammation 26718614 miR-146a inhibits inflammatory activation. transcription factor target hsa-mir-21 Colon Neoplasms 26853468 a DHA-enriched diet induced a decrease of human miR-21 expression and an increase of human TNFα mRNA expression limiting tumor growth in a cancer cell-derived TNFα dependent manner. transcription factor target hsa-let-7a Lung Neoplasms 26962302 The present study reveals that decreased C/EBPα contributes to the down-regulation of miRNA let-7a-1 in lung cancer cells. transcription factor target hsa-mir-200b "Adenocarcinoma, Lung" 27027446 the double-negative feedback loop between E2F3b and miR-200b regulates docetaxel chemosensitivity of human LAD cells transcription factor target hsa-mir-142 "Leukemia, Promyelocytic, Acute" 27480083 Our results suggest the existence of a Vav1/PU.1/miR-142-3p network that supports ATRA-induced differentiation in APL-derived cells transcription factor target hsa-mir-7 "Carcinoma, Hepatocellular" 27519414 Suppression of MicroRNA-7 (miR-7) Biogenesis by Nuclear Factor 90-Nuclear Factor 45 Complex (NF90-NF45) Controls Cell Proliferation in Hepatocellular Carcinoma. transcription factor target hsa-mir-199a-2 Sickle Cell Disease 27573019 Activated Transcription Factor 3 in Association with Histone Deacetylase 6 Negatively Regulates MicroRNA 199a2 Transcription by Chromatin Remodeling and Reduces Endothelin-1 Expression. transcription factor target hsa-mir-34a "Adenocarcinoma, Pancreatic Ductal" 27594424 EZH2 coupled with HOTAIR to silence MicroRNA-34a by the induction of heterochromatin formation in human pancreatic ductal adenocarcinoma. transcription factor target hsa-mir-22 "Leukemia, Myeloid, Acute" 27617961 The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia. transcription factor target hsa-mir-1246 "Carcinoma, Hepatocellular" 27639189 Octamer 4/microRNA-1246 signaling axis drives Wnt/¦Â-catenin activation in liver cancer stem cells. transcription factor target hsa-mir-126 Vascular Disease [unspecific] 27780851 "GATA2-mediated regulation of miR-126 and miR-221 has an important impact on endothelial biology. Hence, modulation of GATA2 and its targets miR-126 and miR-221 is a promising therapeutic strategy for treatment of many vascular diseases" transcription factor target hsa-mir-221 Vascular Disease [unspecific] 27780851 "GATA2-mediated regulation of miR-126 and miR-221 has an important impact on endothelial biology. Hence, modulation of GATA2 and its targets miR-126 and miR-221 is a promising therapeutic strategy for treatment of many vascular diseases" transcription factor target hsa-mir-424 Prostate Neoplasms 27820701 MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression. transcription factor target hsa-mir-29b "Carcinoma, Ovarian" 27832631 A Double-Negative Feedback Interaction between MicroRNA-29b and DNMT3A/3B Contributes to Ovarian Cancer Progression. transcription factor target hsa-mir-127 "Carcinoma, Lung" 27869168 miR-127 promotes EMT and stem-like traits in lung cancer through a feed-forward regulatory loop. transcription factor target hsa-mir-126 Atherosclerosis 27870587 17¦Â-Estradiol Enhances Vascular Endothelial Ets-1/miR-126-3p Expression: The Possible Mechanism for Attenuation of Atherosclerosis. transcription factor target hsa-mir-33 Atherosclerosis 27905947 Fibroblast growth factor 21 potentially inhibits microRNA-33 expression to affect macrophage actions. transcription factor target hsa-mir-148a "Carcinoma, Bladder" 27906180 miR-148a-3p represses proliferation and EMT by establishing regulatory circuits between ERBB3/AKT2/c-myc and DNMT1 in bladder cancer. transcription factor target hsa-mir-31 "Carcinoma, Hepatocellular" 27909734 Klf4 inhibits tumor growth and metastasis by targeting microRNA-31 in human hepatocellular carcinoma. transcription factor target hsa-mir-3158 Neoplasms [unspecific] 27919789 "Unravelling a p73-regulated network: The role of a novel p73-dependent target, MIR3158, in cancer cell migration and invasiveness." transcription factor target hsa-mir-31 Colon Neoplasms 27926494 p38 and JNK pathways control E-selectin-dependent extravasation of colon cancer cells by modulating miR-31 transcription. transcription factor target hsa-mir-493 Neoplasms [unspecific] 27956702 Snail-Modulated MicroRNA 493 Forms a Negative Feedback Loop with the Insulin-Like Growth Factor 1 Receptor Pathway and Blocks Tumorigenesis. transcription factor target hsa-mir-520d "Carcinoma, Gastric" 28011625 Gastric Cancer Cell Proliferation and Survival Is Enabled by a Cyclophilin B/STAT3/miR-520d-5p Signaling Feedback Loop. transcription factor target hsa-mir-574 "Carcinoma, Gastric" 28042090 Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-¦Â1. transcription factor target hsa-mir-23b "Carcinoma, Cervical" 28077801 Human papillomavirus type 16 E6 suppresses microRNA-23b expression in human cervical cancer cells through DNA methylation of the host gene C9orf3. transcription factor target hsa-mir-101 "Carcinoma, Breast" 28109909 ERK2-ZEB1-miR-101-1 axis contributes to epithelial-mesenchymal transition and cell migration in cancer. transcription factor target hsa-mir-139 Neoplasms [unspecific] 28119089 The p53 protein induces stable miRNAs that have the potential to modify subsequent p53 responses. transcription factor target hsa-mir-143 Neoplasms [unspecific] 28119089 The p53 protein induces stable miRNAs that have the potential to modify subsequent p53 responses. transcription factor target hsa-mir-145 Neoplasms [unspecific] 28119089 The p53 protein induces stable miRNAs that have the potential to modify subsequent p53 responses. transcription factor target hsa-mir-34a Neoplasms [unspecific] 28119089 The p53 protein induces stable miRNAs that have the potential to modify subsequent p53 responses. transcription factor target hsa-mir-519d "Carcinoma, Ovarian" 28146423 E2F-1 targets miR-519d to regulate the expression of the ras homolog gene family member C. transcription factor target hsa-mir-181b "Carcinoma, Prostate" 28184935 Involvement of EZH2 in aerobic glycolysis of prostate cancer through miR-181b/HK2 axis. transcription factor target hsa-mir-30a "Carcinoma, Ovarian" 28222434 A Feedback Loop Between miR-30a/c-5p and DNMT1 Mediates Cisplatin Resistance in Ovarian Cancer Cells. transcription factor target hsa-mir-30c "Carcinoma, Ovarian" 28222434 A Feedback Loop Between miR-30a/c-5p and DNMT1 Mediates Cisplatin Resistance in Ovarian Cancer Cells. transcription factor target hsa-mir-146a "Leukemia, Myeloid, Acute" 28399410 Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia. transcription factor target hsa-mir-423 "Diabetes Mellitus, Type 2" 28411267 NFE2 Induces miR-423-5p to Promote Gluconeogenesis and Hyperglycemia by Repressing the Hepatic FAM3A-ATP-Akt Pathway. transcription factor target hsa-mir-182 Melanoma 28412746 Kr¨¹ppel-like factor 4 (KLF4) regulates the miR-183~96~182 cluster under physiologic and pathologic conditions. transcription factor target hsa-mir-183 Melanoma 28412746 Kr¨¹ppel-like factor 4 (KLF4) regulates the miR-183~96~182 cluster under physiologic and pathologic conditions. transcription factor target hsa-mir-96 Melanoma 28412746 Kr¨¹ppel-like factor 4 (KLF4) regulates the miR-183~96~182 cluster under physiologic and pathologic conditions. transcription factor target hsa-mir-192 "Carcinoma, Hepatocellular" 28465351 An HNF4¦Á-microRNA-194/192 signaling axis maintains hepatic cell function. transcription factor target hsa-mir-194 "Carcinoma, Hepatocellular" 28465351 An HNF4¦Á-microRNA-194/192 signaling axis maintains hepatic cell function. transcription factor target hsa-mir-21 Pulmonary Hypertension 28522568 Peroxisome proliferator-activated receptor-¦Ã enhances human pulmonary artery smooth muscle cell apoptosis through microRNA-21 and programmed cell death 4. transcription factor target hsa-mir-29a Atherosclerosis 28593745 ox-LDL increases microRNA-29a transcription through upregulating YY1 and STAT1 in macrophages. transcription factor target hsa-mir-182 "Leukemia, Myeloid, Acute" 28663557 Disruption of the C/EBP¦Á-miR-182 balance impairs granulocytic differentiation. transcription factor target hsa-mir-192 Neoplasms [unspecific] 19074876 Our results showing a role for miR-192/215 in cell proliferation combined with recent observations that these miRNAs are underexpressed in primary cancers support the idea that miR-192 and miR-215 function as tumor suppressors. transcription factor target hsa-mir-215 Neoplasms [unspecific] 19074876 Our results showing a role for miR-192/215 in cell proliferation combined with recent observations that these miRNAs are underexpressed in primary cancers support the idea that miR-192 and miR-215 function as tumor suppressors. transcription factor target hsa-mir-1-1 Inflammation 20098732 "Low density miR array demonstrated that TWEAK inhibits the expression of several miRs including muscle-specific miR-1-1, miR-1-2, miR-133a, miR-133b and miR-206." transcription factor target hsa-mir-1-2 Inflammation 20098732 "Low density miR array demonstrated that TWEAK inhibits the expression of several miRs including muscle-specific miR-1-1, miR-1-2, miR-133a, miR-133b and miR-206." transcription factor target hsa-mir-133a Inflammation 20098732 "Low density miR array demonstrated that TWEAK inhibits the expression of several miRs including muscle-specific miR-1-1, miR-1-2, miR-133a, miR-133b and miR-206." transcription factor target hsa-mir-133b Inflammation 20098732 "Low density miR array demonstrated that TWEAK inhibits the expression of several miRs including muscle-specific miR-1-1, miR-1-2, miR-133a, miR-133b and miR-206." transcription factor target hsa-mir-206 Inflammation 20098732 "Low density miR array demonstrated that TWEAK inhibits the expression of several miRs including muscle-specific miR-1-1, miR-1-2, miR-133a, miR-133b and miR-206." transcription factor target hsa-mir-34a Breast Neoplasms 26553365 Here we show that SNAI2 down-regulates miR34a expression in hypoxic MCF7 cell-derived mammospheres. transcription factor target hsa-let-7 Prostate Neoplasms 27197175 "In cancer cells, reduced expression of ESE3/EHF upregulated Lin28A and Lin28B and downregulated the let-7 microRNAs." transcription factor target hsa-mir-132 Glioma 27522003 "The expression of miR-132 was low in human glioma tissues, and the downregulated expression was associated with advanced glioma grades." transcription factor target hsa-mir-124 Hepatitis C Virus Infection 27753084 Decline of miR-124 in myeloid cells promotes regulatory T-cell development in hepatitis C virus infection. transcription factor target hsa-mir-26a "Lymphoma, Burkitt" 18713946 "Interestingly, miR-26a was also found to be deregulated in primary human Burkitt lymphoma samples, thereby probably being of clinical relevance." transcription factor target hsa-mir-141 Liver Neoplasms 19167416 "the livers of 2-AAF-exposed rats were characterized by the substantial deregulation of expression of miR-18, miR-21, miR-182, and miR-200 family, microRNAs involved in control of apoptosis/cell proliferation and cell-cell contact pathways, two major pathways disrupted during the promotion stage of hepatocarcinogenesis" transcription factor target hsa-mir-18 Liver Neoplasms 19167416 "the livers of 2-AAF-exposed rats were characterized by the substantial deregulation of expression of miR-18, miR-21, miR-182, and miR-200 family, microRNAs involved in control of apoptosis/cell proliferation and cell-cell contact pathways, two major pathways disrupted during the promotion stage of hepatocarcinogenesis" transcription factor target hsa-mir-182 Liver Neoplasms 19167416 "the livers of 2-AAF-exposed rats were characterized by the substantial deregulation of expression of miR-18, miR-21, miR-182, and miR-200 family, microRNAs involved in control of apoptosis/cell proliferation and cell-cell contact pathways, two major pathways disrupted during the promotion stage of hepatocarcinogenesis" transcription factor target hsa-mir-200a Liver Neoplasms 19167416 "the livers of 2-AAF-exposed rats were characterized by the substantial deregulation of expression of miR-18, miR-21, miR-182, and miR-200 family, microRNAs involved in control of apoptosis/cell proliferation and cell-cell contact pathways, two major pathways disrupted during the promotion stage of hepatocarcinogenesis" transcription factor target hsa-mir-200b Liver Neoplasms 19167416 "the livers of 2-AAF-exposed rats were characterized by the substantial deregulation of expression of miR-18, miR-21, miR-182, and miR-200 family, microRNAs involved in control of apoptosis/cell proliferation and cell-cell contact pathways, two major pathways disrupted during the promotion stage of hepatocarcinogenesis" transcription factor target hsa-mir-200c Liver Neoplasms 19167416 "the livers of 2-AAF-exposed rats were characterized by the substantial deregulation of expression of miR-18, miR-21, miR-182, and miR-200 family, microRNAs involved in control of apoptosis/cell proliferation and cell-cell contact pathways, two major pathways disrupted during the promotion stage of hepatocarcinogenesis" transcription factor target hsa-mir-21 Liver Neoplasms 19167416 "the livers of 2-AAF-exposed rats were characterized by the substantial deregulation of expression of miR-18, miR-21, miR-182, and miR-200 family, microRNAs involved in control of apoptosis/cell proliferation and cell-cell contact pathways, two major pathways disrupted during the promotion stage of hepatocarcinogenesis" transcription factor target hsa-mir-429 Liver Neoplasms 19167416 "the livers of 2-AAF-exposed rats were characterized by the substantial deregulation of expression of miR-18, miR-21, miR-182, and miR-200 family, microRNAs involved in control of apoptosis/cell proliferation and cell-cell contact pathways, two major pathways disrupted during the promotion stage of hepatocarcinogenesis" transcription factor target hsa-mir-143 Atherosclerosis 20351064 "Thus, dysregulation of the miR-143 and -145 genes is causally involved in the aberrant SMC plasticity encountered during vascular disease, in part through the up-regulation of an autoregulatory loop that promotes podosome formation." transcription factor target hsa-mir-145 Atherosclerosis 20351064 "Thus, dysregulation of the miR-143 and -145 genes is causally involved in the aberrant SMC plasticity encountered during vascular disease, in part through the up-regulation of an autoregulatory loop that promotes podosome formation." transcription factor target hsa-mir-1275 Glioblastoma 25129238 "We show miR-210-3p, miR-1275, miR-376c-3p, miR-23b-3p, miR-193a-3p and miR-145-5p to be up-regulated, while miR-92b-3p, miR-20a-5p, miR-10b-5p, miR-181a-2-3p and miR-185-5p are down-regulated by hypoxia." transcription factor target hsa-mir-146a "Carcinoma, Thyroid, Anaplastic" 20061417 Nuclear factor-{kappa}B contributes to anaplastic thyroid carcinomas through up-regulation of miR-146a. transcription factor target hsa-mir-146a Inflammation 20098732 The expression of a few miRs including miR-146a and miR-455 was found to be significantly increased in response to TWEAK treatment. transcription factor target hsa-mir-455 Inflammation 20098732 The expression of a few miRs including miR-146a and miR-455 was found to be significantly increased in response to TWEAK treatment. transcription factor target hsa-mir-221 Melanoma 21711453 "MicroRNAs-221 and -222 are highly upregulated in several solid tumors, including melanomas." transcription factor target hsa-mir-222 Melanoma 21711453 "MicroRNAs-221 and -222 are highly upregulated in several solid tumors, including melanomas." transcription factor target hsa-mir-145 Bladder Neoplasms 26196183 The most hypoxia-upregulated miRNA was miR-145. transcription factor target hsa-mir-34a Alzheimer Disease 27235866 miR-34a over expression in patient's tissue transcription factor target hsa-mir-146a "Lymphoma, B-Cell" 18066065 c-Myc repressed this miRNA transcription factor target hsa-mir-150 "Lymphoma, B-Cell" 18066065 c-Myc repressed this miRNA transcription factor target hsa-mir-15a "Lymphoma, B-Cell" 18066065 c-Myc repressed this miRNA transcription factor target hsa-mir-195 "Lymphoma, B-Cell" 18066065 c-Myc repressed this miRNA transcription factor target hsa-mir-22 "Lymphoma, B-Cell" 18066065 c-Myc repressed this miRNA transcription factor target hsa-mir-26b "Lymphoma, B-Cell" 18066065 c-Myc repressed this miRNA transcription factor target hsa-mir-29a "Lymphoma, B-Cell" 18066065 c-Myc repressed this miRNA transcription factor target hsa-mir-29c "Lymphoma, B-Cell" 18066065 c-Myc repressed this miRNA transcription factor target hsa-mir-30e "Lymphoma, B-Cell" 18066065 c-Myc repressed this miRNA transcription factor target hsa-mir-34a "Lymphoma, B-Cell" 18066065 c-Myc repressed this miRNA transcription factor target hsa-mir-210 Breast Neoplasms 18316553 induced transcription factor target hsa-mir-221 Melanoma 18417445 suppressing transcription factor target hsa-mir-222 Melanoma 18417445 suppressing transcription factor target hsa-mir-19a PTEN Hamartoma Tumor Tyndrome 18460397 overexpressed transcription factor target hsa-mir-21 PTEN Hamartoma Tumor Tyndrome 18460397 overexpressed transcription factor target hsa-mir-425 Glioblastoma 18765229 up-regulation in the CD133-cells transcription factor target hsa-mir-451a Glioblastoma 18765229 miR-451: MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells transcription factor target hsa-mir-486 Glioblastoma 18765229 up-regulation in the CD133-cells transcription factor target hsa-mir-1-1 Lung Neoplasms 18818206 miR-1: Down-regulation transcription factor target hsa-mir-1-2 Lung Neoplasms 18818206 miR-1: Down-regulation transcription factor target hsa-mir-21 Neoplasms [unspecific] 18850008 "miR-21: oncomir, An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation" transcription factor target hsa-mir-29a Rhabdomyosarcoma 18977326 miR-29: NF-kappaB-YY1-miR-29 regulatory circuitry transcription factor target hsa-mir-192 Colon Neoplasms 19088023 miR-192: the effect of miR-192 on cellular proliferation is mainly p53 dependent transcription factor target hsa-mir-17 "Leukemia-Lymphoma, Adult T-Cell" 19148830 miR-17: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia transcription factor target hsa-mir-18a "Leukemia-Lymphoma, Adult T-Cell" 19148830 miR-18a: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia transcription factor target hsa-mir-19a "Leukemia-Lymphoma, Adult T-Cell" 19148830 miR-19a: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia transcription factor target hsa-mir-19b-1 "Leukemia-Lymphoma, Adult T-Cell" 19148830 miR-19b: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia transcription factor target hsa-mir-19b-2 "Leukemia-Lymphoma, Adult T-Cell" 19148830 miR-19b: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia transcription factor target hsa-mir-20a "Leukemia-Lymphoma, Adult T-Cell" 19148830 miR-20a: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia transcription factor target hsa-mir-92a-1 "Leukemia-Lymphoma, Adult T-Cell" 19148830 miR-92a: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia transcription factor target hsa-mir-92a-2 "Leukemia-Lymphoma, Adult T-Cell" 19148830 miR-92a: Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia transcription factor target hsa-mir-146a Breast Neoplasms 19190326 "miR-146: Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis" transcription factor target hsa-mir-146b Breast Neoplasms 19190326 "miR-146: Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis" transcription factor target hsa-mir-26a-1 Lymphoma 19197161 miR-26a: repressed by MYC transcription factor target hsa-mir-26a-2 Lymphoma 19197161 miR-26a: repressed by MYC transcription factor target hsa-mir-145 Neoplasms [unspecific] 19202062 "miR-145: putative tumor suppressor, miR-145 provides a direct link between p53 and c-Myc in this gene regulatory network" transcription factor target hsa-mir-21 Breast Neoplasms 19264808 miR-21: Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells. transcription factor target hsa-mir-21 Breast Neoplasms 19308091 miR-21: BMP-6 inhibits microRNA-21 expression in breast cancer through repressing deltaEF1 and AP-1 transcription factor target hsa-mir-146a Osteoarthritis 19333945 miR-146a: miR-146 is intensely expressed in low-grade OA cartilage and that its expression is induced by stimulation of IL-1beta transcription factor target hsa-mir-17 Medulloblastoma 19351822 miR-17: the most highly up-regulated miRNAs in medulloblastoma transcription factor target hsa-mir-18a Medulloblastoma 19351822 miR-18a: the most highly up-regulated miRNAs in medulloblastoma transcription factor target hsa-mir-19a Medulloblastoma 19351822 miR-19a: the most highly up-regulated miRNAs in medulloblastoma transcription factor target hsa-mir-19b-1 Medulloblastoma 19351822 miR-19b: the most highly up-regulated miRNAs in medulloblastoma transcription factor target hsa-mir-19b-2 Medulloblastoma 19351822 miR-19b: the most highly up-regulated miRNAs in medulloblastoma transcription factor target hsa-mir-20a Medulloblastoma 19351822 miR-20a: the most highly up-regulated miRNAs in medulloblastoma transcription factor target hsa-mir-92a-1 Medulloblastoma 19351822 miR-92a: the most highly up-regulated miRNAs in medulloblastoma transcription factor target hsa-mir-92a-2 Medulloblastoma 19351822 miR-92a: the most highly up-regulated miRNAs in medulloblastoma transcription factor target hsa-mir-222 Brain Neoplasms 19351827 miR-222: Overexpression transcription factor target hsa-mir-222 Prostate Neoplasms 19351827 miR-222: Overexpression transcription factor target hsa-mir-23a "Cardiomyopathy, Hypertrophic" 19574461 miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy transcription factor target hsa-mir-18a Neoplasms [unspecific] 19706389 "significantly upregulated, downregulate Eralpha" transcription factor target hsa-mir-143 Wounds and Injuries [unspecific] 19720868 modulate cytoskeletal dynamics and responsiveness transcription factor target hsa-mir-145 Wounds and Injuries [unspecific] 19720868 modulate cytoskeletal dynamics and responsiveness transcription factor target hsa-mir-21 Prostate Neoplasms 19738047 hsa-mir-21: an androgen receptor-regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth transcription factor target hsa-mir-223 "Leukemia, Myeloid, Acute" 20018373 miR-223:miR-223 suppression in AML is caused by impaired miR-223 upstream factors transcription factor target hsa-mir-195 Schizophrenia 20156358 EGR3 and hsa-miR-195 were core regulators transcription factor target hsa-mir-34a Disease of Metabolism 20185821 Our study demonstrates an unexpected role of the FXR/SHP pathway in controlling SIRT1 levels via miR-34a inhibition and that elevated miR-34a levels in obese mice contribute to decreased SIRT1 levels transcription factor target hsa-mir-34a Neoplasms [unspecific] 20185821 Our study demonstrates an unexpected role of the FXR/SHP pathway in controlling SIRT1 levels via miR-34a inhibition and that elevated miR-34a levels in obese mice contribute to decreased SIRT1 levels transcription factor target hsa-mir-221 "Leukemia, Lymphocytic, Chronic, B-Cell" 20203269 miR-221:miR-221/222 and p27 may represent a regulatory loop that helps maintaining CLL cells in a resting condition transcription factor target hsa-mir-222 "Leukemia, Lymphocytic, Chronic, B-Cell" 20203269 miR-222:miR-221/222 and p27 may represent a regulatory loop that helps maintaining CLL cells in a resting condition transcription factor target hsa-mir-519c Neoplasms [unspecific] 20233879 MicroRNA-519c suppresses hypoxia-inducible factor-1alpha expression and tumor angiogenesis transcription factor target hsa-mir-210 Ischemia 20308562 demonstrated a key role of miR-210 in limiting keratinocyte proliferation transcription factor target hsa-mir-221 Breast Neoplasms 20388878 These findings suggest that the negative regulatory loop involving miR-221-222 and ERalpha may confer proliferative advantage and migratory activity to breast cancer cells and promote the transition from ER-positive to ER-negative tumors transcription factor target hsa-mir-222 Breast Neoplasms 20388878 These findings suggest that the negative regulatory loop involving miR-221-222 and ERalpha may confer proliferative advantage and migratory activity to breast cancer cells and promote the transition from ER-positive to ER-negative tumors transcription factor target hsa-mir-106b Prostate Neoplasms 20388916 We showed that miR-22 and the miR-106b~25 cluster are aberrantly overexpressed in human prostate cancer transcription factor target hsa-mir-22 Prostate Neoplasms 20388916 We showed that miR-22 and the miR-106b~25 cluster are aberrantly overexpressed in human prostate cancer transcription factor target hsa-mir-25 Prostate Neoplasms 20388916 We showed that miR-22 and the miR-106b~25 cluster are aberrantly overexpressed in human prostate cancer transcription factor target hsa-mir-93 Prostate Neoplasms 20388916 We showed that miR-22 and the miR-106b~25 cluster are aberrantly overexpressed in human prostate cancer transcription factor target hsa-mir-23a "Leukemia, Myeloid" 20399246 the 23a cluster is the first downstream miRNA target implicated in regulating the development of myeloid versus lymphoid cells. transcription factor target hsa-let-7a-1 Neoplasms [unspecific] 20404092 "let-7a:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells" transcription factor target hsa-let-7a-2 Neoplasms [unspecific] 20404092 "let-7a:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells" transcription factor target hsa-let-7a-3 Neoplasms [unspecific] 20404092 "let-7a:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells" transcription factor target hsa-let-7i Neoplasms [unspecific] 20404092 "let-7i:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells" transcription factor target hsa-mir-106b Neoplasms [unspecific] 20404092 "mir-106b-25:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells" transcription factor target hsa-mir-15b Neoplasms [unspecific] 20404092 "mir-15b-16-2:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells" transcription factor target hsa-mir-25 Neoplasms [unspecific] 20404092 "mir-106b-25:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells" transcription factor target hsa-mir-93 Neoplasms [unspecific] 20404092 "mir-106b-25:let-7a-d, let-7i, mir-15b-16-2, and mir-106b-25, are direct targets of E2F1 and E2F3 during G(1)/S and are repressed in E2F1/3-null cells" transcription factor target hsa-mir-192 Renal Fibrosis 20488955 miR-192:miR-192 mediates TGF-beta/Smad3-driven renal fibrosis transcription factor target hsa-mir-21 Heart Failure 20546595 We show that the transcription factor p53 piggy-backs onto NF-kappaB/RELA and utilizes the kappaB-motif at a cis-regulatory region to control mir-21 expression. transcription factor target hsa-mir-10b Nasopharyngeal Neoplasms 20732742 MicroRNA-10b induced by Epstein-Barr virus-encoded latent membrane protein-1 promotes the metastasis of human nasopharyngeal carcinoma cells transcription factor target hsa-mir-155 Pancreatic Neoplasms 20871480 miR-155:Human SMG-1 is Involved in Gemcitabine-Induced Primary microRNA-155/BIC Up-Regulation in Human Pancreatic Cancer PANC-1 Cells transcription factor target hsa-mir-199b Heart Failure 21102440 "miR-199b is a direct calcineurin/NFAT target gene that increases in expression in mouse and human heart failure, and targets the nuclear NFAT kinase dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a (Dyrk1a)" transcription factor target hsa-mir-221 Glioblastoma 21245048 NF-kB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells. transcription factor target hsa-mir-221 Prostate Neoplasms 21245048 NF-kB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells. transcription factor target hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 21296997 MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia. transcription factor target hsa-let-7a-2 Lung Neoplasms 21365266 "9-cis-RA, all-trans-RA,lithium chloride and CEBP might play important regulatory roles in let-7a2 gene expression in A549 cells" transcription factor target hsa-mir-200a Lung Neoplasms 21403400 The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. transcription factor target hsa-mir-200b Lung Neoplasms 21403400 The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. transcription factor target hsa-mir-200c Lung Neoplasms 21403400 The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. transcription factor target hsa-mir-451a "Leukemia-Lymphoma, Adult T-Cell" 21464222 Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL. transcription factor target hsa-mir-122 "Carcinoma, Hepatocellular" 21654638 MicroRNA122 is a key regulator of alpha-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma. transcription factor target hsa-mir-222 Lung Neoplasms 21656127 High-mobility group A1 proteins enhance the expression of the oncogenic miR-222 in lung cancer cells. transcription factor target hsa-mir-181a-2 "Carcinoma, Hepatocellular" 21711587 Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma. transcription factor target hsa-mir-181b-1 "Carcinoma, Hepatocellular" 21711587 Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma. transcription factor target hsa-mir-181b-2 "Carcinoma, Hepatocellular" 21711587 Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma. transcription factor target hsa-mir-181c "Carcinoma, Hepatocellular" 21711587 Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma. transcription factor target hsa-mir-181d "Carcinoma, Hepatocellular" 21711587 Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma. transcription factor target hsa-mir-132 Myocardial Infarction 21868695 Transplantation of Human Pericyte Progenitor Cells Improves the Repair of Infarcted Heart Through Activation of an Angiogenic Program Involving Micro-RNA-132. transcription factor target hsa-mir-135a-1 "Carcinoma, Hepatocellular" 21888875 MicroRNA-135a Contributes to the Development of Portal Vein Tumor Thrombus by Promoting Metastasis in Hepatocellular Carcinoma. transcription factor target hsa-mir-135a-2 "Carcinoma, Hepatocellular" 21888875 MicroRNA-135a Contributes to the Development of Portal Vein Tumor Thrombus by Promoting Metastasis in Hepatocellular Carcinoma. transcription factor target hsa-mir-125b-1 Hematologic Neoplasms 21903586 "Mir-125b, a target of CDX2, regulates cell differentiation through the repression of the core binding factor in hematopoietic malignancies." transcription factor target hsa-mir-125b-2 Hematologic Neoplasms 21903586 "Mir-125b, a target of CDX2, regulates cell differentiation through the repression of the core binding factor in hematopoietic malignancies." transcription factor target hsa-let-7a-1 "Carcinoma, Hepatocellular" 21903590 C-myc Inhibits the Transcription of the MicroRNA Cluster MC-let-7a-1~let-7d via a Non-Canonical E-box. transcription factor target hsa-let-7d "Carcinoma, Hepatocellular" 21903590 C-myc Inhibits the Transcription of the MicroRNA Cluster MC-let-7a-1~let-7d via a Non-Canonical E-box. transcription factor target hsa-let-7f-1 "Carcinoma, Hepatocellular" 21903590 C-myc Inhibits the Transcription of the MicroRNA Cluster MC-let-7a-1~let-7d via a Non-Canonical E-box. transcription factor target hsa-mir-135b Lymphoma 22042699 miR-135b mediates NPM-ALK-driven oncogenicity and renders IL-17-producing immunophenotype to anaplastic large cell lymphoma. transcription factor target hsa-mir-143 "Leukemia, Myeloid, Acute" 22093444 "miR-143 and miR-145 expression is significantly repressed in primary AML patient samples as compared to neutrophils of healthy donors. Further analysis revealed impaired neutrophil differentiation of APL cells upon inhibition of miR-145 expression. Lastly, we identified p73 as transcriptional regulator of miR-143/145 during neutrophil differentiation of APL cells. Our data suggest that low miR-145 levels in APL, possibly due to aberrant expression of p73 transcription factors, contribute to the differentiation block seen in this disease." transcription factor target hsa-mir-145 "Leukemia, Myeloid, Acute" 22093444 "miR-143 and miR-145 expression is significantly repressed in primary AML patient samples as compared to neutrophils of healthy donors. Further analysis revealed impaired neutrophil differentiation of APL cells upon inhibition of miR-145 expression. Lastly, we identified p73 as transcriptional regulator of miR-143/145 during neutrophil differentiation of APL cells. Our data suggest that low miR-145 levels in APL, possibly due to aberrant expression of p73 transcription factors, contribute to the differentiation block seen in this disease." transcription factor target hsa-mir-125b-1 Osteosarcoma 22093834 miR-125b suppresses the proliferation and migration of osteosarcoma cells through down-regulation of STAT3. transcription factor target hsa-mir-125b-2 Osteosarcoma 22093834 miR-125b suppresses the proliferation and migration of osteosarcoma cells through down-regulation of STAT3. transcription factor target hsa-mir-155 Inflammation 22170100 Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*. transcription factor target hsa-mir-224 "Carcinoma, Hepatocellular" 22178270 Transcriptional regulation of mir-224 upregulated in human HCCs by NFkB inflammatory pathways. transcription factor target hsa-mir-23b Breast Neoplasms 22231442 "ERalpha downregulates miR-30a by binding to two specific sites proximal to the gene and thereby inhibiting pri-miR synthesis. On the other hand, the receptor promotes miR-23b, -27b and 24-1 accumulation in the cell by binding in close proximity of the corresponding gene cluster and preventing in situ the inhibitory effects of ER§Ø©ãon pri-miR maturation by the p68/DDX5-Drosha microprocessor complex." transcription factor target hsa-mir-24-1 Breast Neoplasms 22231442 "ERalpha downregulates miR-30a by binding to two specific sites proximal to the gene and thereby inhibiting pri-miR synthesis. On the other hand, the receptor promotes miR-23b, -27b and 24-1 accumulation in the cell by binding in close proximity of the corresponding gene cluster and preventing in situ the inhibitory effects of ER§Ø©ãon pri-miR maturation by the p68/DDX5-Drosha microprocessor complex." transcription factor target hsa-mir-27b Breast Neoplasms 22231442 "ERalpha downregulates miR-30a by binding to two specific sites proximal to the gene and thereby inhibiting pri-miR synthesis. On the other hand, the receptor promotes miR-23b, -27b and 24-1 accumulation in the cell by binding in close proximity of the corresponding gene cluster and preventing in situ the inhibitory effects of ER§Ø©ãon pri-miR maturation by the p68/DDX5-Drosha microprocessor complex." transcription factor target hsa-mir-30a Breast Neoplasms 22231442 "ERalpha downregulates miR-30a by binding to two specific sites proximal to the gene and thereby inhibiting pri-miR synthesis. On the other hand, the receptor promotes miR-23b, -27b and 24-1 accumulation in the cell by binding in close proximity of the corresponding gene cluster and preventing in situ the inhibitory effects of ER§Ø©ãon pri-miR maturation by the p68/DDX5-Drosha microprocessor complex." transcription factor target hsa-mir-29b-1 Lung Neoplasms 22249264 MicroRNA-29b is involved in the Src-ID1 signaling pathway and is dysregulated in human lung adenocarcinoma. transcription factor target hsa-mir-29b-2 Lung Neoplasms 22249264 MicroRNA-29b is involved in the Src-ID1 signaling pathway and is dysregulated in human lung adenocarcinoma. transcription factor target hsa-mir-10b Breast Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. transcription factor target hsa-mir-10b Colon Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. transcription factor target hsa-mir-17 Breast Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. transcription factor target hsa-mir-17 Colon Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. transcription factor target hsa-mir-21 Breast Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. transcription factor target hsa-mir-21 Colon Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. transcription factor target hsa-mir-9-1 Breast Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. transcription factor target hsa-mir-9-1 Colon Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. transcription factor target hsa-mir-9-2 Breast Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. transcription factor target hsa-mir-9-2 Colon Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. transcription factor target hsa-mir-9-3 Breast Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. transcription factor target hsa-mir-9-3 Colon Neoplasms 22286762 Sulindac inhibits tumor cell invasion by suppressing NF-kB-mediated transcription of microRNAs. transcription factor target hsa-mir-200a Colorectal Carcinoma 22286765 SIX1-induced CDH1 repression and EMT in CRC cells were correlated at least in part with posttranscriptional ZEB1 activation and miR-200-family transcriptional repression. transcription factor target hsa-mir-200b Colorectal Carcinoma 22286765 SIX1-induced CDH1 repression and EMT in CRC cells were correlated at least in part with posttranscriptional ZEB1 activation and miR-200-family transcriptional repression. transcription factor target hsa-mir-200c Colorectal Carcinoma 22286765 SIX1-induced CDH1 repression and EMT in CRC cells were correlated at least in part with posttranscriptional ZEB1 activation and miR-200-family transcriptional repression. transcription factor target hsa-mir-34a Esophageal Neoplasms 22292433 Transcriptional activation of microRNA-34a by NF-kappa B in human esophageal cancer cells. transcription factor target hsa-mir-196b Gastric Neoplasms 22298639 miR-196b expression was significantly repressed by ETS2 during gastric cancer oncogenesis. transcription factor target hsa-mir-199a-1 "Carcinoma, Hepatocellular" 22359598 ER Stress Negatively Modulates the Expression of the miR-199a/214 Cluster to Regulates Tumor Survival and Progression in Human Hepatocellular Cancer. transcription factor target hsa-mir-199a-2 "Carcinoma, Hepatocellular" 22359598 ER Stress Negatively Modulates the Expression of the miR-199a/214 Cluster to Regulates Tumor Survival and Progression in Human Hepatocellular Cancer. transcription factor target hsa-mir-214 "Carcinoma, Hepatocellular" 22359598 ER Stress Negatively Modulates the Expression of the miR-199a/214 Cluster to Regulates Tumor Survival and Progression in Human Hepatocellular Cancer. transcription factor target hsa-let-7a-1 Breast Neoplasms 22388088 "SHP2 activated stemness-associated transcription factors, including v-myc myelocytomatosis viral oncogene homolog (c-Myc) and zinc finger E-box binding homeobox 1 (ZEB1), which resulted in the repression of let-7 microRNA and the expression of a set of 'SHP2 signature' genes." transcription factor target hsa-let-7a-2 Breast Neoplasms 22388088 "SHP2 activated stemness-associated transcription factors, including v-myc myelocytomatosis viral oncogene homolog (c-Myc) and zinc finger E-box binding homeobox 1 (ZEB1), which resulted in the repression of let-7 microRNA and the expression of a set of 'SHP2 signature' genes." transcription factor target hsa-let-7a-3 Breast Neoplasms 22388088 "SHP2 activated stemness-associated transcription factors, including v-myc myelocytomatosis viral oncogene homolog (c-Myc) and zinc finger E-box binding homeobox 1 (ZEB1), which resulted in the repression of let-7 microRNA and the expression of a set of 'SHP2 signature' genes." transcription factor target hsa-let-7b Breast Neoplasms 22388088 "SHP2 activated stemness-associated transcription factors, including v-myc myelocytomatosis viral oncogene homolog (c-Myc) and zinc finger E-box binding homeobox 1 (ZEB1), which resulted in the repression of let-7 microRNA and the expression of a set of 'SHP2 signature' genes." transcription factor target hsa-let-7c Breast Neoplasms 22388088 "SHP2 activated stemness-associated transcription factors, including v-myc myelocytomatosis viral oncogene homolog (c-Myc) and zinc finger E-box binding homeobox 1 (ZEB1), which resulted in the repression of let-7 microRNA and the expression of a set of 'SHP2 signature' genes." transcription factor target hsa-let-7d Breast Neoplasms 22388088 "SHP2 activated stemness-associated transcription factors, including v-myc myelocytomatosis viral oncogene homolog (c-Myc) and zinc finger E-box binding homeobox 1 (ZEB1), which resulted in the repression of let-7 microRNA and the expression of a set of 'SHP2 signature' genes." transcription factor target hsa-let-7e Breast Neoplasms 22388088 "SHP2 activated stemness-associated transcription factors, including v-myc myelocytomatosis viral oncogene homolog (c-Myc) and zinc finger E-box binding homeobox 1 (ZEB1), which resulted in the repression of let-7 microRNA and the expression of a set of 'SHP2 signature' genes." transcription factor target hsa-let-7f-1 Breast Neoplasms 22388088 "SHP2 activated stemness-associated transcription factors, including v-myc myelocytomatosis viral oncogene homolog (c-Myc) and zinc finger E-box binding homeobox 1 (ZEB1), which resulted in the repression of let-7 microRNA and the expression of a set of 'SHP2 signature' genes." transcription factor target hsa-let-7f-2 Breast Neoplasms 22388088 "SHP2 activated stemness-associated transcription factors, including v-myc myelocytomatosis viral oncogene homolog (c-Myc) and zinc finger E-box binding homeobox 1 (ZEB1), which resulted in the repression of let-7 microRNA and the expression of a set of 'SHP2 signature' genes." transcription factor target hsa-let-7g Breast Neoplasms 22388088 "SHP2 activated stemness-associated transcription factors, including v-myc myelocytomatosis viral oncogene homolog (c-Myc) and zinc finger E-box binding homeobox 1 (ZEB1), which resulted in the repression of let-7 microRNA and the expression of a set of 'SHP2 signature' genes." transcription factor target hsa-let-7i Breast Neoplasms 22388088 "SHP2 activated stemness-associated transcription factors, including v-myc myelocytomatosis viral oncogene homolog (c-Myc) and zinc finger E-box binding homeobox 1 (ZEB1), which resulted in the repression of let-7 microRNA and the expression of a set of 'SHP2 signature' genes." transcription factor target hsa-mir-155 Breast Neoplasms 22797073 Mutant p53 drives invasion in breast tumors through up-regulation of miR-155. transcription factor target hsa-mir-302a Head And Neck Neoplasms 22847005 "Hyaluronan-CD44v3 interaction with Oct4/Sox2/Nanog promotes miR-302 expression leading to self-renewal, clonal formation and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma." transcription factor target hsa-mir-302b Head And Neck Neoplasms 22847005 "Hyaluronan-CD44v3 interaction with Oct4/Sox2/Nanog promotes miR-302 expression leading to self-renewal, clonal formation and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma." transcription factor target hsa-mir-302c Head And Neck Neoplasms 22847005 "Hyaluronan-CD44v3 interaction with Oct4/Sox2/Nanog promotes miR-302 expression leading to self-renewal, clonal formation and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma." transcription factor target hsa-mir-302d Head And Neck Neoplasms 22847005 "Hyaluronan-CD44v3 interaction with Oct4/Sox2/Nanog promotes miR-302 expression leading to self-renewal, clonal formation and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma." transcription factor target hsa-mir-302e Head And Neck Neoplasms 22847005 "Hyaluronan-CD44v3 interaction with Oct4/Sox2/Nanog promotes miR-302 expression leading to self-renewal, clonal formation and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma." transcription factor target hsa-mir-302f Head And Neck Neoplasms 22847005 "Hyaluronan-CD44v3 interaction with Oct4/Sox2/Nanog promotes miR-302 expression leading to self-renewal, clonal formation and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma." transcription factor target hsa-mir-29c Influenza 22850539 Induction of the cellular microRNA-29c by influenza virus contributes to virus-mediated apoptosis through repression of antiapoptotic factors BCL2L2. transcription factor target hsa-mir-373 Cholangiocarcinoma 22876037 Mutual regulation between microRNA-373 and methyl-CpG-binding domain protein 2 in hilar cholangiocarcinoma. transcription factor target hsa-mir-132 Prostate Neoplasms 22916239 Luteolin Induces microRNA-132 Expression and Modulates Neurite Outgrowth in PC12 Cells. transcription factor target hsa-mir-9-1 Colon Neoplasms 23045246 Prospero homeobox 1 promotes epithelial-mesenchymal transition in colon cancer cells by inhibiting E-cadherin via miR-9 transcription factor target hsa-mir-9-2 Colon Neoplasms 23045246 Prospero homeobox 1 promotes epithelial-mesenchymal transition in colon cancer cells by inhibiting E-cadherin via miR-9 transcription factor target hsa-mir-720 Esophageal Neoplasms 23154181 SnoN/SKIL modulates proliferation through control of hsa-miR-720 transcription in esophageal cancer cells transcription factor target hsa-mir-150 "Scleroderma, Systemic" 23159943 miR-150 Down-Regulation Contributes to the Constitutive Type I Collagen Overexpression in Scleroderma Dermal Fibroblasts via the Induction of Integrin §Ø©ã transcription factor target hsa-mir-9-1 Glioma 23185366 The CREB-miR-9 negative feedback minicircuitry coordinates the migration and proliferation of glioma cells transcription factor target hsa-mir-9-2 Glioma 23185366 The CREB-miR-9 negative feedback minicircuitry coordinates the migration and proliferation of glioma cells transcription factor target hsa-mir-29b-1 Multiple Myeloma 23190608 miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1 transcription factor target hsa-mir-29b-2 Multiple Myeloma 23190608 miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1 transcription factor target hsa-mir-138-1 "Leukemia, Myeloid" 23208504 BCR-ABL/GATA1/miR-138 mini circuitry contributes to the leukemogenesis of chronic myeloid leukemia transcription factor target hsa-mir-138-2 "Leukemia, Myeloid" 23208504 BCR-ABL/GATA1/miR-138 mini circuitry contributes to the leukemogenesis of chronic myeloid leukemia transcription factor target hsa-mir-205 Urinary Bladder Cancer 23239884 The p63 isoform deltaNp63§Ø©ãinhibits epithelial-mesenchymal transition in human bladder cancer cells: Role of miR205 transcription factor target hsa-mir-370 Neoplasms [unspecific] 23333300 Stat3 inhibits WTX expression through up-regulation of microRNA-370 in Wilms tumor transcription factor target hsa-mir-21 Liver Neoplasms 23355454 microRNA 21-mediated suppression of Sprouty1 by Pokemon affects liver cancer cell growth and proliferation transcription factor target hsa-mir-221 Melanoma 23400877 The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway transcription factor target hsa-mir-222 Melanoma 23400877 The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway transcription factor target hsa-mir-30d "Carcinoma, Renal Cell" 23416459 MiR-30d induces apoptosis and is regulated by the Akt/FOXO pathway in renal cell carcinoma transcription factor target hsa-mir-203 Breast Neoplasms 23447531 Signaling between TGF-beta and Transcription factor SNAI2 Represses Expression of microRNA miR-203 to Promote Epithelial-Mesenchymal Transition and Tumor Metastasis transcription factor target hsa-mir-125b-1 Prostate Neoplasms 23503464 Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells transcription factor target hsa-mir-125b-2 Prostate Neoplasms 23503464 Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells transcription factor target hsa-mir-99a Prostate Neoplasms 23503464 Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells transcription factor target hsa-mir-125b-1 "Lymphoma, T-Cell" 23527180 cMyc/miR-125b-5p Signalling Determines Sensitivity to Bortezomib in Preclinical Model of Cutaneous T-Cell Lymphomas transcription factor target hsa-mir-125b-2 "Lymphoma, T-Cell" 23527180 cMyc/miR-125b-5p Signalling Determines Sensitivity to Bortezomib in Preclinical Model of Cutaneous T-Cell Lymphomas transcription factor target hsa-mir-191 Breast Neoplasms 23542418 "MicroRNA-191, an estrogen responsive microRNA, functions as an oncogenic regulator in human breast cancer" transcription factor target hsa-mir-144 Alzheimer Disease 23546882 MicroRNA-144 Is Regulated by Activator Protein-1 (AP-1) and Decreases Expression of Alzheimer's Disease-related A Disintegrin And Metalloprotease 10 (ADAM10) transcription factor target hsa-mir-506 Breast Neoplasms 23717581 miR-506 Regulates Epithelial Mesenchymal Transition in Breast Cancer Cell Lines. transcription factor target hsa-mir-370 "Carcinoma, Hepatocellular" 23728999 Perturbation of miR-370-LIN28A-NF-¦ÊB regulatory circuit contributes to the development of hepatocellular carcinoma. transcription factor target hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 23750211 Signal Transducer and Activator of Transcription-3 Induces MicroRNA-155 Expression in Chronic Lymphocytic Leukemia. transcription factor target hsa-mir-27a Breast Neoplasms 23752185 miR-27a regulates endothelial differentiation of breast cancer stem like cells. transcription factor target hsa-mir-200a Neoplasms [unspecific] 23759590 KDM5B histone demethylase controls epithelial-mesenchymal transition of cancer cells by regulating the expression of the microRNA-200 family. transcription factor target hsa-mir-200b Neoplasms [unspecific] 23759590 KDM5B histone demethylase controls epithelial-mesenchymal transition of cancer cells by regulating the expression of the microRNA-200 family. transcription factor target hsa-mir-200c Neoplasms [unspecific] 23759590 KDM5B histone demethylase controls epithelial-mesenchymal transition of cancer cells by regulating the expression of the microRNA-200 family. transcription factor target hsa-mir-127 "Carcinoma, Hepatocellular" 23762330 A Feedback Inhibition between miRNA-127 and TGFbeta/c-Jun Cascade in HCC Cell Migration via MMP13. transcription factor target hsa-mir-199a-1 "Muscular Dystrophy, Duchenne" 23764775 "MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation." transcription factor target hsa-mir-199a-2 "Muscular Dystrophy, Duchenne" 23764775 "MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation." transcription factor target hsa-mir-134 "Carcinoma, Hepatocellular" 23775631 Hepatocyte nuclear factor-4¦Á reverses malignancy of hepatocellular carcinoma through regulating mir-134 in the DLK1-DIO3 region. transcription factor target hsa-mir-373 Pancreatic Neoplasms 23857777 A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth. transcription factor target hsa-mir-1 Neoplasms [unspecific] 23921124 Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis. transcription factor target hsa-mir-206 Neoplasms [unspecific] 23921124 Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis. transcription factor target hsa-mir-205 Prostate Neoplasms 23924028 The evidence that miR-205 replacement in PCa cells is able not only to prevent but also to revert the oxidative/pro-inflammatory axis leading to EMT induced by CAFs sets the rationale for developing miRNA-based approaches to prevent and treat metastatic disease. transcription factor target hsa-mir-125b "Carcinoma, Cervical" 23928699 OCT4 promotes tumorigenesis and inhibits apoptosis of cervical cancer cells by miR-125b/BAK1 pathway. transcription factor target hsa-mir-23a Gastrointestinal Neoplasms 23929433 miR-23a inhibits E-cadherin expression and is regulated by AP-1 and NFAT4 complex during Fas-induced EMT in gastrointestinal cancer. transcription factor target hsa-mir-143 Neoplasms [unspecific] 23932921 DDX6 post-transcriptionally down-regulates miR-143/145 expression through host gene NCR143/145 in cancer cells. transcription factor target hsa-mir-145 Neoplasms [unspecific] 23932921 DDX6 post-transcriptionally down-regulates miR-143/145 expression through host gene NCR143/145 in cancer cells. transcription factor target hsa-mir-20b Breast Neoplasms 23945289 Crucial role for early growth response-1 in the transcriptional regulation of miR-20b in breast cancer. transcription factor target hsa-mir-30c "Leukemia, Myeloid, Acute" 23974200 Transcription factor C/EBP¦Á-induced microRNA-30c inactivates Notch1 during granulopoiesis and is downregulated in acute myeloid leukemia. transcription factor target hsa-mir-204 Diabetes Mellitus 23975026 The newly identified TXNIP-miR-204-MAFA-insulin pathway may contribute to diabetes progression and provides new insight into TXNIP function and microRNA biology in health and disease. transcription factor target hsa-mir-141 Breast Neoplasms 23975430 Significance of PELP1/HDAC2/miR-200 regulatory network in EMT and metastasis of breast cancer. transcription factor target hsa-mir-200a Breast Neoplasms 23975430 Significance of PELP1/HDAC2/miR-200 regulatory network in EMT and metastasis of breast cancer. transcription factor target hsa-mir-224 "Carcinoma, Hepatocellular" 23988648 miR-224 is critical for celastrol-induced inhibition of migration and invasion of hepatocellular carcinoma cells. transcription factor target hsa-mir-198 Pancreatic Neoplasms 23989979 "miR-198 acts as a central tumor suppressor and modulates the molecular makeup of a critical interactome in pancreatic cancer, indicating a potential prognostic marker signature and the therapeutic potential of attacking this tumorigenic network through a central vantage point." transcription factor target hsa-mir-122 "Carcinoma, Hepatocellular" 24038073 Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2. transcription factor target hsa-mir-155 Breast Neoplasms 24080728 MicroRNA-155 broadly orchestrates inflammation-induced changes of microRNA expression in breast cancer transcription factor target hsa-mir-26a Glioblastoma 24140063 C-Myc negatively controls the tumor suppressor PTEN by upregulating miR-26a in glioblastoma multiforme cells. transcription factor target hsa-mir-203 "Carcinoma, Colon" 24145190 Maintenance of the stemness in CD44(+) HCT-15 and HCT-116 human colon cancer cells requires miR-203 suppression. transcription factor target hsa-mir-365 Gastric Neoplasms 24149576 Akt-p53-miR-365-cyclin D1/cdc25A axis contributes to gastric tumorigenesis induced by PTEN deficiency. transcription factor target hsa-mir-184 "Carcinoma, Nasopharyngeal" 24157866 Tumor suppressor PDCD4 modulates miR-184-mediated direct suppression of C-MYC and BCL2 blocking cell growth and survival in nasopharyngeal carcinoma. transcription factor target hsa-mir-200c Prostate Neoplasms 24186205 TMPRSS2-ERG gene fusions induce prostate tumorigenesis by modulating microRNA miR-200c. transcription factor target hsa-mir-548 "Lymphoma, Non-Hodgkin" 24216476 A microenvironment-mediated c-Myc/miR-548m/HDAC6 amplification loop in non-Hodgkin B cell lymphomas. transcription factor target hsa-mir-183 Neoplasms [unspecific] 24277930 A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster. transcription factor target hsa-mir-15a Colorectal Carcinoma 24285725 p53-induced miR-15a/16-1 and AP4 form a double-negative feedback loop to regulate epithelial-mesenchymal transition and metastasis in colorectal cancer. transcription factor target hsa-mir-16-1 Colorectal Carcinoma 24285725 p53-induced miR-15a/16-1 and AP4 form a double-negative feedback loop to regulate epithelial-mesenchymal transition and metastasis in colorectal cancer. transcription factor target hsa-mir-106b Breast Neoplasms 24292682 high level of miR-106b induced by TGF-¦Â determines the tumor-promoting effects of TGF-¦Â in breast cancer. transcription factor target hsa-mir-221 Glioblastoma 24295494 miR-221/222 confers radioresistance in glioblastoma cells through activating Akt independent of PTEN status. transcription factor target hsa-mir-222 Glioblastoma 24295494 miR-221/222 confers radioresistance in glioblastoma cells through activating Akt independent of PTEN status. transcription factor target hsa-mir-183 Gastric Neoplasms 24335145 Glycogen synthase kinase 3 beta inhibits microRNA-183-96-182 cluster via the ¦Â-Catenin/TCF/LEF-1 pathway in gastric cancer cells. transcription factor target hsa-mir-96 Gastric Neoplasms 24335145 Glycogen synthase kinase 3 beta inhibits microRNA-183-96-182 cluster via the ¦Â-Catenin/TCF/LEF-1 pathway in gastric cancer cells. transcription factor target hsa-mir-17 Cardiovascular Diseases [unspecific] 24378993 Crosstalk between TGF-¦Â/Smad3 and BMP/BMPR2 signaling pathways via miR-17-92 cluster in carotid artery restenosis. transcription factor target hsa-mir-18 Cardiovascular Diseases [unspecific] 24378993 Crosstalk between TGF-¦Â/Smad3 and BMP/BMPR2 signaling pathways via miR-17-92 cluster in carotid artery restenosis. transcription factor target hsa-mir-19a Cardiovascular Diseases [unspecific] 24378993 Crosstalk between TGF-¦Â/Smad3 and BMP/BMPR2 signaling pathways via miR-17-92 cluster in carotid artery restenosis. transcription factor target hsa-mir-19b-1 Cardiovascular Diseases [unspecific] 24378993 Crosstalk between TGF-¦Â/Smad3 and BMP/BMPR2 signaling pathways via miR-17-92 cluster in carotid artery restenosis. transcription factor target hsa-mir-20a Cardiovascular Diseases [unspecific] 24378993 Crosstalk between TGF-¦Â/Smad3 and BMP/BMPR2 signaling pathways via miR-17-92 cluster in carotid artery restenosis. transcription factor target hsa-mir-92-1 Cardiovascular Diseases [unspecific] 24378993 Crosstalk between TGF-¦Â/Smad3 and BMP/BMPR2 signaling pathways via miR-17-92 cluster in carotid artery restenosis. transcription factor target hsa-mir-199a Testicular Germ Cell Tumor 24391856 Molecular mechanisms of regulation and action of microRNA-199a in testicular germ cell tumor and glioblastomas. transcription factor target hsa-mir-134 Glioblastoma 24440911 "Multiple receptor tyrosine kinases converge on microRNA-134 to control KRAS,STAT5B, and glioblastoma." transcription factor target hsa-mir-320a Colorectal Carcinoma 24454819 E2A predicts prognosis of colorectal cancer patients and regulates cancer cell growth by targeting miR-320a. transcription factor target hsa-mir-145 "Diabetes Mellitus, Type 2" 24548410 miR-145 plays a role in the development of resistin-induced insulin resistance via the p65 pathway. transcription factor target hsa-mir-146a Colorectal Carcinoma 24561623 MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. transcription factor target hsa-mir-31 Breast Neoplasms 24582497 The breast cancer oncogene EMSY represses transcription of antimetastatic microRNA miR-31. transcription factor target hsa-mir-100 Neoplasms [unspecific] 24586203 "miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion." transcription factor target hsa-mir-146b "Carcinoma, Esophageal" 24589738 Transcriptional regulation of miR-146b by C/EBP¦Â LAP2 in esophageal cancer cells. transcription factor target hsa-mir-26a Idiopathic Pulmonary Fibrosis 24594795 The antifibrotic effects and mechanisms of microRNA-26a action in idiopathic pulmonary fibrosis. transcription factor target hsa-mir-204 "Carcinoma, Nasopharyngeal" 24613926 Down-regulation of miRNA-204 by LMP-1 enhances CDC42 activity and facilitates invasion of EBV-associated nasopharyngeal carcinoma cells. transcription factor target hsa-mir-124 Colorectal Carcinoma 24619225 The pro-apoptotic role of the regulatory feedback loop between miR-124 and PKM1/HNF4¦Á in colorectal cancer cells. transcription factor target hsa-mir-145 Colorectal Carcinoma 24631504 Peroxisome proliferator-activated receptor ¦Ã-mediated induction of microRNA-145 opposes tumor phenotype in colorectal cancer. transcription factor target hsa-mir-34a Colorectal Carcinoma 24642471 IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis. transcription factor target hsa-mir-29 "Diabetes Mellitus, Type 2" 24722248 MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes. transcription factor target hsa-mir-223 "Leukemia, Lymphoblastic, Acute, T-Cell" 24727676 Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia. transcription factor target hsa-mir-210 Melanoma 24767210 Distinct microRNA expression signatures are associated with melanoma subtypes and are regulated by HIF1A. transcription factor target hsa-mir-218 Melanoma 24767210 Distinct microRNA expression signatures are associated with melanoma subtypes and are regulated by HIF1A. transcription factor target hsa-mir-224 Melanoma 24767210 Distinct microRNA expression signatures are associated with melanoma subtypes and are regulated by HIF1A. transcription factor target hsa-mir-452 Melanoma 24767210 Distinct microRNA expression signatures are associated with melanoma subtypes and are regulated by HIF1A. transcription factor target hsa-mir-181c Hepatitis C Virus Infection 24789793 Transcriptional suppression of miR-181c by hepatitis C virus enhances homeobox A1 expression. transcription factor target hsa-mir-200b "Adenocarcinoma, Lung" 24830600 the HDAC1/4/Sp1/miR-200b/E2F3 pathway is responsible for chemoresistance of docetaxel-resistant LAD cells. transcription factor target hsa-mir-28 "Lymphoma, B-Cell" 24843176 MicroRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas. transcription factor target hsa-mir-509 "Carcinoma, Hepatocellular" 24882622 The oncoprotein HBXIP up-regulates SCG3 through modulating E2F1 and miR-509-3p in hepatoma cells. transcription factor target hsa-mir-210 Idiopathic Pulmonary Fibrosis 24951777 miR-210 promotes IPF fibroblast proliferation in response to hypoxia. transcription factor target hsa-mir-128 Glioma 24959930 "An axis involving SNAI1, microRNA-128 and SP1 modulates glioma progression." transcription factor target hsa-mir-21 Myocardial Ischemic-Reperfusion Injury 24983504 A feedback regulatory loop between HIF-1¦Á and miR-21 in response to hypoxia in cardiomyocytes. transcription factor target hsa-mir-203 "Squamous Cell Carcinoma, Esophageal" 24994936 EGF-induced C/EBP¦Â participates in EMT by decreasing the expression of miR-203 in esophageal squamous cell carcinoma cells. transcription factor target hsa-mir-199a Gastric Neoplasms 25080937 SRF expedites metastasis and modulates the epithelial to mesenchymal transition by regulating miR-199a-5p expression in human gastric cancer. transcription factor target hsa-mir-21 "Carcinoma, Hepatocellular" 25087183 Hepatitis B virus X protein promotes hepatocellular carcinoma transformation through interleukin-6 activation of microRNA-21 expression. transcription factor target hsa-mir-155 "Leukemia, Myeloid, Acute" 25092123 LIFR¦Á-CT3 induces differentiation of a human acute myelogenous leukemia cell line HL-60 by suppressing miR-155 expression through the JAK/STAT pathway. transcription factor target hsa-mir-191 Pancreatic Neoplasms 25119596 The clinical significance and regulation mechanism of hypoxia-inducible factor-1 and miR-191 expression in pancreatic cancer. transcription factor target hsa-mir-9 MELAS Syndrome 25149473 The ROS-sensitive microRNA-9/9* controls the expression of mitochondrial tRNA-modifying enzymes and is involved in the molecular mechanism of MELAS syndrome. transcription factor target hsa-mir-590 Breast Neoplasms 25150595 A feedback expression of microRNA-590 and activating transcription factor-3 in human breast cancer cells. transcription factor target hsa-mir-425 Gastric Neoplasms 25154996 There is a critical role for NF-kappa B-dependent up-regulation of miR-425. And it represents a new pathway for the repression of phosphatase and tensin homolog activation and the promotion of cell survival upon IL-1¦Â induction. transcription factor target hsa-mir-31 "Carcinoma, Oral" 25229239 EGF up-regulates miR-31 through the C/EBP¦Â signal cascade in oral carcinoma. transcription factor target hsa-mir-1 "Carcinoma, Nasopharyngeal" 25237831 EZH2 promotes angiogenesis through inhibition of miR-1/Endothelin-1 axis in nasopharyngeal carcinoma. transcription factor target hsa-mir-200b "Adenocarcinoma, Lung" 25279705 Histone deacetylase 1/Sp1/microRNA-200b signaling accounts for maintenance of cancer stem-like cells in human lung adenocarcinoma. transcription factor target hsa-mir-21 Glioma 25305446 Kr¨¹ppel-like factor 9 inhibits glioma cell proliferation and tumorigenicity via downregulation of miR-21. transcription factor target hsa-mir-125b-1 "Leukemia, Myeloid, Acute" 25323587 NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival. transcription factor target hsa-mir-29b-1 "Leukemia, Myeloid, Acute" 25323587 NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival. transcription factor target hsa-mir-31 Prostate Neoplasms 25341040 Polycomb protein EZH2 suppresses apoptosis by silencing the proapoptotic miR-31. transcription factor target hsa-mir-224 Melanoma 25341426 E2F1 induces miR-224/452 expression to drive EMT through TXNIP downregulation. transcription factor target hsa-mir-452 Melanoma 25341426 E2F1 induces miR-224/452 expression to drive EMT through TXNIP downregulation. transcription factor target hsa-mir-200 "Carcinoma, Colon" 25371200 MicroRNA-200 (miR-200) cluster regulation by achaete scute-like 2 (Ascl2): impact on the epithelial-mesenchymal transition in colon cancer cells. transcription factor target hsa-mir-188 Alzheimer Disease 25378159 Synaptic and cognitive improvements by inhibition of 2-AG metabolism are through upregulation of microRNA-188-3p in a mouse model of Alzheimer's disease. transcription factor target hsa-let-7c Breast Neoplasms 25388283 "HER2 protein expression and activity are negatively correlated with let-7c expression in TCGA. In summary, we identified an ER-regulated miRNA cluster that regulates HER2, is lost with progression to estrogen independence, and may serve as a biomarker of poor outcome in ER(+) luminal A breast cancer patients." transcription factor target hsa-mir-125b Breast Neoplasms 25388283 "HER2 protein expression and activity are negatively correlated with let-7c expression in TCGA. In summary, we identified an ER-regulated miRNA cluster that regulates HER2, is lost with progression to estrogen independence, and may serve as a biomarker of poor outcome in ER(+) luminal A breast cancer patients." transcription factor target hsa-mir-99a Breast Neoplasms 25388283 "HER2 protein expression and activity are negatively correlated with let-7c expression in TCGA. In summary, we identified an ER-regulated miRNA cluster that regulates HER2, is lost with progression to estrogen independence, and may serve as a biomarker of poor outcome in ER(+) luminal A breast cancer patients." transcription factor target hsa-mir-182 Breast Neoplasms 25394902 The miR-183/-96/-182 cluster is up-regulated in most breast cancer. It functions as an oncogene in breast cancer as it increases cell proliferation and migration. transcription factor target hsa-mir-183 Breast Neoplasms 25394902 The miR-183/-96/-182 cluster is up-regulated in most breast cancer. It functions as an oncogene in breast cancer as it increases cell proliferation and migration. transcription factor target hsa-mir-96 Breast Neoplasms 25394902 The miR-183/-96/-182 cluster is up-regulated in most breast cancer. It functions as an oncogene in breast cancer as it increases cell proliferation and migration. transcription factor target hsa-mir-648 Pulmonary Hypertension 25403488 These studies provide a novel link wherein PlGF-mediated downregulation of PAX5 attenuates miR-648 expression leading to increased ET-1 levels that are known to induce PHT in SCA. transcription factor target hsa-mir-139 Gastric Neoplasms 25499265 "Given that miR-139 and Jun are deregulated in many cancers, our findings here might have broader implication in other types of human cancers" transcription factor target hsa-mir-96 Prostate Neoplasms 25531317 a novel mechanism accounting for the TGF¦Â signaling and bone metastasis. transcription factor target hsa-mir-17 "Leukemia, Myeloid, Acute" 25612891 the extent of KIT-induced proliferation itself can modulate myeloid differentiation of cells with wild type RUNX1 function. transcription factor target hsa-mir-31 "Carcinoma, Esophageal" 25644061 SOX4 interacts with EZH2 and HDAC3 to suppress microRNA-31 in invasive esophageal cancer cells. transcription factor target hsa-mir-638 Melanoma 25650662 miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy. transcription factor target hsa-mir-203 "Carcinoma, Cervical" 25658920 BANF1 is downregulated by IRF1-regulated microRNA-203 in cervical cancer. transcription factor target hsa-mir-203 Helicobacter pylori Infection 25689935 Our results demonstrated that H. pylori infection induced hepatic insulin resistance by the c-Jun/miR-203/SOCS3 signaling pathway and provide possible implications with regard to resolving insulin resistance. transcription factor target hsa-mir-148a Neoplasms [unspecific] 25703326 Regulatory circuit of PKM2/NF-¦ÊB/miR-148a/152-modulated tumor angiogenesis and cancer progression. transcription factor target hsa-mir-152 Neoplasms [unspecific] 25703326 Regulatory circuit of PKM2/NF-¦ÊB/miR-148a/152-modulated tumor angiogenesis and cancer progression. transcription factor target hsa-mir-146 Breast Neoplasms 25712342 FOXP3 Controls an miR-146/NF-¦ÊB Negative Feedback Loop That Inhibits Apoptosis in Breast Cancer Cells. transcription factor target hsa-mir-31 "Carcinoma, Breast" 25737447 "These studies further suggest that manipulation of miR-31 expression can be used to modulate senescence-related pathological conditions such as cancer,and the aging process." transcription factor target hsa-mir-100 "Carcinoma, Cervical" 25757558 "Transcriptional regulation of microRNA-100, -146a, and -150 genes by p53 and NF¦ÊB p65/RelA in mouse striatal STHdh(Q7)/ Hdh(Q7) cells and human cervical carcinoma HeLa cells." transcription factor target hsa-mir-146a "Carcinoma, Cervical" 25757558 "Transcriptional regulation of microRNA-100, -146a, and -150 genes by p53 and NF¦ÊB p65/RelA in mouse striatal STHdh(Q7)/ Hdh(Q7) cells and human cervical carcinoma HeLa cells." transcription factor target hsa-mir-150 "Carcinoma, Cervical" 25757558 "Transcriptional regulation of microRNA-100, -146a, and -150 genes by p53 and NF¦ÊB p65/RelA in mouse striatal STHdh(Q7)/ Hdh(Q7) cells and human cervical carcinoma HeLa cells." transcription factor target hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 25799148 Modulation of the NF-¦ÊB/miR-21/PTEN pathway in NSCLC showed that inhibition of this pathway may increase cisplatin sensitivity. transcription factor target hsa-mir-182 "Carcinoma, Hepatocellular" 25813403 Wnt/¦Â-Catenin activates MiR-183/96/182 expression in hepatocellular carcinoma that promotes cell invasion. transcription factor target hsa-mir-183 "Carcinoma, Hepatocellular" 25813403 Wnt/¦Â-Catenin activates MiR-183/96/182 expression in hepatocellular carcinoma that promotes cell invasion. transcription factor target hsa-mir-96 "Carcinoma, Hepatocellular" 25813403 Wnt/¦Â-Catenin activates MiR-183/96/182 expression in hepatocellular carcinoma that promotes cell invasion. transcription factor target hsa-mir-210 Obesity 25833255 "Our data suggest that the inflammatory intrauterine environment associated with maternal obesity induces an NF¦ÊB1-mediated increase in miR-210 in a fetal sex-dependent manner, leading to inhibition of mitochondrial respiration and placental dysfunction in the placentas of female fetuses." transcription factor target hsa-mir-191 Breast Neoplasms 25867965 HIF-inducible miR-191 promotes migration in breast cancer through complex regulation of TGF¦Â-signaling in hypoxic microenvironment. transcription factor target hsa-mir-371 Colorectal Carcinoma 25868860 "The SOX17/miR-371-5p/SOX2 axis inhibits EMT, stem cell properties and metastasis in colorectal cancer." transcription factor target hsa-mir-182 Breast Neoplasms 25873390 Autocrine/Paracrine Human Growth Hormone-stimulated MicroRNA 96-182-183 Cluster Promotes Epithelial-Mesenchymal Transition and Invasion in Breast Cancer. transcription factor target hsa-mir-183 Breast Neoplasms 25873390 Autocrine/Paracrine Human Growth Hormone-stimulated MicroRNA 96-182-183 Cluster Promotes Epithelial-Mesenchymal Transition and Invasion in Breast Cancer. transcription factor target hsa-mir-96 Breast Neoplasms 25873390 Autocrine/Paracrine Human Growth Hormone-stimulated MicroRNA 96-182-183 Cluster Promotes Epithelial-Mesenchymal Transition and Invasion in Breast Cancer. transcription factor target hsa-mir-214 Sickle Cell Disease 25876995 Erythropoietin-mediated expression of placenta growth factor is regulated via activation of hypoxia-inducible factor-1¦Á and post-transcriptionally by miR-214 in sickle cell disease. transcription factor target hsa-mir-494 Lymphoma 25907832 The PTEN-AKT-mTOR/RICTOR Pathway in Nasal Natural Killer Cell Lymphoma Is Activated by miR-494-3p via PTEN But Inhibited by miR-142-3p via RICTOR. transcription factor target hsa-mir-593 "Squamous Cell Carcinoma, Tongue" 25912308 Mitochondrial fission determines cisplatin sensitivity in tongue squamous cell carcinoma through the BRCA1-miR-593-5p-MFF axis. transcription factor target hsa-mir-124 "Lymphoma, B-Cell" 25915824 MicroRNA-124 links p53 to the NF-¦ÊB pathway in B-cell lymphomas. transcription factor target hsa-mir-31 Breast Neoplasms 25927669 A novel mechanism of regulation of the anti-metastatic miR-31 by EMSY in breast cancer. transcription factor target hsa-mir-451 Glioblastoma 25937278 "These findings uncover miR-451 as a major effector of glucose-regulated AMPK signaling, allowing tumor cell adaptation to variations in nutrient availability in the tumor microenvironment." transcription factor target hsa-mir-218 Glioblastoma 25943352 Feedback circuitry between miR-218 repression and RTK activation in glioblastoma. transcription factor target hsa-mir-125b Ovarian Neoplasms 25944662 PPAR¦Ã inhibits ovarian cancer cells proliferation through upregulation of miR-125b. transcription factor target hsa-mir-30 Heart Failure 25950484 "we describe that DOX causes acute and sustained miR-30 downregulation in cardiomyocytes via GATA-6. miR-30 overexpression protects cardiac cells from DOX-induced apoptosis, and its maintenance represents a potential cardioprotective and anti-tumorigenic strategy for anthracyclines." transcription factor target hsa-mir-200a Breast Neoplasms 25972084 "our results suggest that Restin inhibits EMT and tumor metastasis by controlling the expression of the tumor metastasis suppressor mir-200a/b via association with p73. Our findings not only establish a mechanistic link between Restin, EMT and tumor metastasis, but also provide strong evidence supporting the notion that MAGE Group II proteins may exert a tumor suppressive effect in vivo." transcription factor target hsa-mir-200b Breast Neoplasms 25972084 "our results suggest that Restin inhibits EMT and tumor metastasis by controlling the expression of the tumor metastasis suppressor mir-200a/b via association with p73. Our findings not only establish a mechanistic link between Restin, EMT and tumor metastasis, but also provide strong evidence supporting the notion that MAGE Group II proteins may exert a tumor suppressive effect in vivo." transcription factor target hsa-mir-125b "Leukemia, Myeloid, Acute" 25982911 The deregulated expression of miR-125b in acute myeloid leukemia is dependent on the transcription factor C/EBP¦Á. transcription factor target hsa-mir-615 "Carcinoma, Hepatocellular" 25987019 PU.1 Is Identified as a Novel Metastasis Suppressor in Hepatocellular Carcinoma Regulating the miR-615-5p/IGF2 Axis. transcription factor target hsa-mir-148a Obesity 26001136 "The results suggest that miR-148a is a biomarker of obesity in human subjects and mouse model, which represents a CREB-modulated miRNA that acts to repress Wnt1, thereby promoting adipocyte differentiation." transcription factor target hsa-mir-34a Obesity 26036628 These data provide first in vitro and in vivo evidence for the leptin-antagonist potential of honokiol (HNK) revealing a crosstalk between HNK and miR34a and Wnt1-MTA1-¦Â-catenin axis. transcription factor target hsa-mir-19a Pancreatic Neoplasms 26041879 Sp1-driven up-regulation of miR-19a decreases RHOB and promotes pancreatic cancer. transcription factor target hsa-mir-23b "Carcinoma, Gastric" 26041881 The reciprocal regulation loop of Notch2 pathway and miR-23b in controlling gastric carcinogenesis. transcription factor target hsa-mir-146a Leukemia 26045293 Differential hypoxic regulation of the microRNA-146a/CXCR4 pathway in normal and leukemic monocytic cells: impact on response to chemotherapy. transcription factor target hsa-mir-1 Prostate Neoplasms 26071255 EGF Receptor Promotes Prostate Cancer Bone Metastasis by Downregulating miR-1 and Activating TWIST1. transcription factor target hsa-mir-338 "Carcinoma, Hepatocellular" 26082033 Mineralocorticoid receptor suppresses cancer progression and the Warburg effect by modulating the miR-338-3p-PKLR axis in hepatocellular carcinoma. transcription factor target hsa-mir-29 Human Immunodeficiency Virus Infection 26108174 IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection. transcription factor target hsa-mir-155 Neoplasms [unspecific] 26156524 the losing equilibrium of the regulatory feedback loop between STAT1 and miR-155-5p influencing tumorigenesis. transcription factor target hsa-mir-224 Lung Neoplasms 26187928 MicroRNA-224 promotes tumor progression in nonsmall cell lung cancer. transcription factor target hsa-mir-29b Glaucoma 26191170 "This study suggests that TGF-¦Â2 has a time-effect relationship with Tenon's capsule fibroblasts proliferation from glaucoma patients, and it stimulates Tenon's capsule fibroblast proliferation via suppression of miR-29b expression regulated by Nrf2." transcription factor target hsa-mir-373 Breast Neoplasms 26196741 MiR-373 drives the epithelial-to-mesenchymal transition and metastasis via the miR-373-TXNIP-HIF1¦Á-TWIST signaling axis in breast cancer. transcription factor target hsa-mir-214 Liver Fibrosis 26229009 These findings reveal a unique function for cellular or exosomal Twist1 in CCN2-dependent fibrogenesis. transcription factor target hsa-mir-182 Soft Tissue Sarcoma 26234681 these results suggest that sarcoma metastasis can be partially controlled through Pax7/MyoD-dependent activation of miR-182 and provide insight into the role that myogenic transcription factors have in sarcoma progression. transcription factor target hsa-mir-22 Lymphoma 26244872 "Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma." transcription factor target hsa-mir-150 "Lymphoma, Large-Cell, Anaplastic" 26258416 "our results suggest that hypomethylating drugs,alone or in combination with other agents, may benefit ALK(+) patients harboring tumors resistant to crizotinib and other anti-ALK tyrosine kinase inhibitors (TKIs). Moreover, these results support further work on miR-150 in these and other ALK(+) malignancies." transcription factor target hsa-mir-130a Neoplasms [unspecific] 26272168 These findings reveal an evolutionarily conserved positive feedback mechanism underlying robustness of the Hippo pathway in size control and tumorigenesis. transcription factor target hsa-mir-206 Muscle Diseases [unspecific] 26272918 MyoD transcription factor induces myogenesis by inhibiting Twist-1 through miR-206. transcription factor target hsa-mir-27a Gastric Neoplasms 26292288 HIF-1¦Á Induces Multidrug Resistance in Gastric Cancer Cells by Inducing MiR-27a. transcription factor target hsa-mir-140 Lung Fibrosis 26300493 "Using these models we showed that IR induces overexpression of Brca1, Nrf2 and miR-140 in lung tissue after irradiation. These data reveal a novel radioprotective mechanism in which IR promotes NRF2 nuclear translocation and subsequent activation of miR-140 transcription in HLFs." transcription factor target hsa-mir-145 "Carcinoma, Renal Cell" 26304926 Androgen receptor (AR) suppresses miRNA-145 to promote renal cell carcinoma (RCC) progression independent of VHL status. transcription factor target hsa-mir-143 Pulmonary Hypertension 26311719 "MiR-143-3p modulated both cellular and exosome-mediated responses in pulmonary vascular cells, whereas inhibition of miR-143-3p blocked experimental pulmonary hypertension. Taken together, these findings confirm an important role for the miR-143/145 cluster in PAH pathobiology." transcription factor target hsa-mir-190a Prostate Neoplasms 26314494 "Taken together, our findings identified a biochemical and functional link between miR-190a with reduced expression in advanced prostate cancer, YB-1 and AR signaling in prostate cancer." transcription factor target hsa-mir-128a Glioma 26324126 IDH1R132H decreases the proliferation of U87 glioma cells through upregulation of microRNA-128a. transcription factor target hsa-mir-204 Lymphoma 26350953 "This study demonstrated that HIF-1¦Á-miR-204-BCL-2 pathway contributed to apoptosis of neuronal cells induced by hypoxia, which could potentially be exploited to prevent spinal cord ischemia-reperfusion injury." transcription factor target hsa-mir-132 Breast Neoplasms 26377202 "Taken together, the findings provide the first evidences of the synergistic anti-metastatic properties of miR-212/132 cluster through suppression of SOX4. Also, current study suggest a new miRNA-based mechanism elucidating the anti-metastatic properties of Ahr agonists, suggesting possibility of using miR-212/132 to control metastasis in breast cancer patients." transcription factor target hsa-mir-212 Breast Neoplasms 26377202 "Taken together, the findings provide the first evidences of the synergistic anti-metastatic properties of miR-212/132 cluster through suppression of SOX4. Also, current study suggest a new miRNA-based mechanism elucidating the anti-metastatic properties of Ahr agonists, suggesting possibility of using miR-212/132 to control metastasis in breast cancer patients." transcription factor target hsa-mir-22 Emphysema 26437241 "Thus, miR-22 is a critical regulator of both emphysema and T(H)17 responses." transcription factor target hsa-mir-129 Breast Neoplasms 26460733 "Thus,miR-129-5p down-regulation fosters EMT in breast cancer by increasing Twist1-Snail and activating a negative feedback loop." transcription factor target hsa-mir-101 "Carcinoma, Hepatocellular" 26718325 These findings show that elevated EZH2 contributes to miR-101 deregulation in HCC and highlight the coordinated role of miR-101 and EZH2 in hepatocarcinogenesis. transcription factor target hsa-mir-101-1 "Carcinoma, Hepatocellular" 26718325 These findings show that elevated EZH2 contributes to miR-101 deregulation in HCC and highlight the coordinated role of miR-101 and EZH2 in hepatocarcinogenesis. transcription factor target hsa-mir-23b Multiple Myeloma 26771806 miR-23b/SP1/c-myc forms a feed-forward loop supporting multiple myeloma cell growth. transcription factor target hsa-mir-124 "Carcinoma, Lung, Non-Small-Cell" 26818357 The feedback loop between miR-124 and TGF-¦Â pathway plays a significant role in non-small cell lung cancer metastasis. transcription factor target hsa-mir-146a Inflammation 26855180 Super enhancers at the miR-146a and miR-155 genes contribute to self-regulation of inflammation. transcription factor target hsa-mir-155 Inflammation 26855180 Super enhancers at the miR-146a and miR-155 genes contribute to self-regulation of inflammation. transcription factor target hsa-mir-130b "Carcinoma, Colon" 27082112 The infinity software that we have developed is a powerful tool to underscore new TF/miRNA regulatory networks. transcription factor target hsa-mir-17 "Carcinoma, Colon" 27082112 The infinity software that we have developed is a powerful tool to underscore new TF/miRNA regulatory networks. transcription factor target hsa-mir-181b "Carcinoma, Colon" 27082112 The infinity software that we have developed is a powerful tool to underscore new TF/miRNA regulatory networks. transcription factor target hsa-mir-21 "Carcinoma, Colon" 27082112 The infinity software that we have developed is a powerful tool to underscore new TF/miRNA regulatory networks. transcription factor target hsa-mir-301b "Carcinoma, Colon" 27082112 The infinity software that we have developed is a powerful tool to underscore new TF/miRNA regulatory networks. transcription factor target hsa-mir-195 "Carcinoma, Hepatocellular" 27179445 Expression of microRNA-195 is transactivated by Sp1 but inhibited by histone deacetylase 3 in hepatocellular carcinoma cells. tissue_expression_down hsa-mir-125a Breast Neoplasms 16103053 downregulation tissue_expression_down hsa-mir-125b-1 Breast Neoplasms 16103053 downregulation tissue_expression_down hsa-mir-125b-2 Breast Neoplasms 16103053 downregulation tissue_expression_down hsa-mir-145 Breast Neoplasms 16103053 downregulation tissue_expression_down hsa-mir-125a "Carcinoma, Hepatocellular" 16331254 downregulated tissue_expression_down hsa-mir-126 Hepatitis C Virus Infection 16331254 downregulated tissue_expression_down hsa-mir-143 Hepatitis C Virus Infection 16331254 downregulated tissue_expression_down hsa-mir-195 "Carcinoma, Hepatocellular" 16331254 downregulated tissue_expression_down hsa-mir-199a-1 "Carcinoma, Hepatocellular" 16331254 downregulated tissue_expression_down hsa-mir-199a-1 Hepatitis C Virus Infection 16331254 downregulated tissue_expression_down hsa-mir-199a-2 "Carcinoma, Hepatocellular" 16331254 downregulated tissue_expression_down hsa-mir-199a-2 Hepatitis C Virus Infection 16331254 downregulated tissue_expression_down hsa-mir-200a "Carcinoma, Hepatocellular" 16331254 downregulated tissue_expression_down hsa-mir-28 Hepatitis C Virus Infection 16331254 downregulated tissue_expression_down hsa-mir-342 Hepatitis C Virus Infection 16331254 downregulated tissue_expression_down hsa-mir-372 Hepatitis C Virus Infection 16331254 downregulated tissue_expression_down hsa-mir-376c Hepatitis C Virus Infection 16331254 downregulated tissue_expression_down hsa-mir-101-1 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-125a Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-126 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-140 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-143 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-145 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-181c Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-192 Lung Neoplasms 16530703 mir-192-prec downregulation tissue_expression_down hsa-mir-198 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-199b Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-216a Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-216b Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-218-2 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-219-1 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-224 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-26a-1 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-27b Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-29b-1 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-30a Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-32 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-33a Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-33b Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-9-1 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-9-2 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-9-3 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-95 Lung Neoplasms 16530703 downregulation tissue_expression_down hsa-mir-1 Vascular Hypertrophy 17008435 MicroRNA-1 and microRNA-133a expression are decreased during skeletal muscle hypertrophy. tissue_expression_down hsa-mir-133a Vascular Hypertrophy 17008435 MicroRNA-1 and microRNA-133a expression are decreased during skeletal muscle hypertrophy. tissue_expression_down hsa-let-7a-1 Neoplasms [unspecific] 17028596 "let-7a-1 downregulated in six solid cancer types by PAM and SAM (Volinia et al., 2006);" tissue_expression_down hsa-let-7a-2 Breast Neoplasms 17028596 "let-7a-2, 7a-3, 7d, 7f-2 downregulated in breast cancer" tissue_expression_down hsa-let-7a-2 Neoplasms [unspecific] 17028596 "Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control." tissue_expression_down hsa-let-7a-3 Breast Neoplasms 17028596 "let-7a-2, 7a-3, 7d, 7f-2 downregulated in breast cancer" tissue_expression_down hsa-let-7a-3 Neoplasms [unspecific] 17028596 "Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control." tissue_expression_down hsa-let-7b Neoplasms [unspecific] 17028596 "Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control." tissue_expression_down hsa-let-7c Neoplasms [unspecific] 17028596 "Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control." tissue_expression_down hsa-let-7d Breast Neoplasms 17028596 "let-7a-2, 7a-3, 7d, 7f-2 downregulated in breast cancer" tissue_expression_down hsa-let-7d Neoplasms [unspecific] 17028596 "Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control." tissue_expression_down hsa-let-7e Neoplasms [unspecific] 17028596 "Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control." tissue_expression_down hsa-let-7f-1 Neoplasms [unspecific] 17028596 "Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control." tissue_expression_down hsa-let-7f-2 Breast Neoplasms 17028596 "let-7a-2, 7a-3, 7d, 7f-2 downregulated in breast cancer" tissue_expression_down hsa-let-7f-2 Neoplasms [unspecific] 17028596 "Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control." tissue_expression_down hsa-let-7g Neoplasms [unspecific] 17028596 "Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control." tissue_expression_down hsa-let-7i Neoplasms [unspecific] 17028596 "Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control." tissue_expression_down hsa-mir-10b Breast Neoplasms 17028596 "mir-10b downregulated in breast cancer (Iorio et al., 2005);" tissue_expression_down hsa-mir-124-1 Lung Neoplasms 17028596 "mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-124-2 Lung Neoplasms 17028596 "mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-124-3 Lung Neoplasms 17028596 "mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-125a Breast Neoplasms 17028596 "mir-125a, b1, b2 downregulated in breast cancer (Iorio et al., 2005);" tissue_expression_down hsa-mir-125b-1 Breast Neoplasms 17028596 "mir-125a, b1, b2 downregulated in breast cancer (Iorio et al., 2005);" tissue_expression_down hsa-mir-125b-2 Breast Neoplasms 17028596 "mir-125a, b1, b2 downregulated in breast cancer (Iorio et al., 2005);" tissue_expression_down hsa-mir-145 Breast Neoplasms 17028596 "mir-145 downregulated in breast cancer (Iorio et al., 2005) and lung cancer and deleted in prostate cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-145 Lung Neoplasms 17028596 "mir-145 downregulated in breast cancer (Iorio et al., 2005) and lung cancer and deleted in prostate cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-145 Prostate Neoplasms 17028596 "mir-145 downregulated in breast cancer (Iorio et al., 2005) and lung cancer and deleted in prostate cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-181c Lung Neoplasms 17028596 "mir-181c-prec downregulated in lung cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-218-2 Lung Neoplasms 17028596 "mir-218-2 downregulated in lung cancer (Yanaihara et al., 2006)" tissue_expression_down hsa-mir-223 Lung Neoplasms 17028596 "mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-26a-1 Lung Neoplasms 17028596 "mir-26a-1-prec downregulated in lung cancer, deleted in epithelial cancers (Yanaihara et al., 2006)" tissue_expression_down hsa-mir-29a Lung Neoplasms 17028596 "mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-29b-1 Lung Neoplasms 17028596 "mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-29b-2 Lung Neoplasms 17028596 "mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-29c Lung Neoplasms 17028596 "mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-30a Lung Neoplasms 17028596 "mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-30b Lung Neoplasms 17028596 "mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006)" tissue_expression_down hsa-mir-30c-1 Lung Neoplasms 17028596 "mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006)" tissue_expression_down hsa-mir-30c-2 Lung Neoplasms 17028596 "mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006)" tissue_expression_down hsa-mir-30d Lung Neoplasms 17028596 "mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006)" tissue_expression_down hsa-mir-30d Neoplasms [unspecific] 17028596 "mir-30d downregulated in six solid cancer types by SAM (Volinia et al., 2006);" tissue_expression_down hsa-mir-30e Lung Neoplasms 17028596 "mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006)" tissue_expression_down hsa-mir-32 Lung Neoplasms 17028596 "mir-32 downregulated in lung cancer (Yanaihara et al., 2006);" tissue_expression_down hsa-mir-34a Breast Neoplasms 17028596 "mir-34 downregulated in breast cancer (Iorio et al., 2005)" tissue_expression_down hsa-mir-34a Lung Neoplasms 17028596 "mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006)" tissue_expression_down hsa-mir-34b Breast Neoplasms 17028596 "mir-34 downregulated in breast cancer (Iorio et al., 2005)" tissue_expression_down hsa-mir-34b Lung Neoplasms 17028596 "mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006)" tissue_expression_down hsa-mir-34c Breast Neoplasms 17028596 "mir-34 downregulated in breast cancer (Iorio et al., 2005)" tissue_expression_down hsa-mir-34c Lung Neoplasms 17028596 "mir-30, mir-34 mir-30a-5p downregulated in lung cancer (Yanaihara et al., 2006)" tissue_expression_down hsa-mir-92a-1 Neoplasms [unspecific] 17028596 "mir-92 downregulated in six solid cancer types by PAM (Volinia et al., 2006)" tissue_expression_down hsa-mir-92a-2 Neoplasms [unspecific] 17028596 "mir-92 downregulated in six solid cancer types by PAM (Volinia et al., 2006)" tissue_expression_down hsa-mir-92b Neoplasms [unspecific] 17028596 "mir-92 downregulated in six solid cancer types by PAM (Volinia et al., 2006)" tissue_expression_down hsa-mir-98 Neoplasms [unspecific] 17028596 "Let-7/mir-98 expression is reduced in tumours, potentially contributing to elevated activity of the Ras pathway and effects on growth control." tissue_expression_down hsa-mir-150 "Cardiomyopathy, Hypertrophic" 17108080 downregulated tissue_expression_down hsa-mir-181b-1 "Cardiomyopathy, Hypertrophic" 17108080 downregulated tissue_expression_down hsa-mir-181b-2 "Cardiomyopathy, Hypertrophic" 17108080 downregulated tissue_expression_down hsa-mir-133a "Adenocarcinoma, Pancreatic Ductal" 17237814 The expression of miR-216 and -217 and lack of expression of miR-133a were identified as characteristic of pancreas tissue. tissue_expression_down hsa-mir-195 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-20b Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-212 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-24-1 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-24-2 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-26b Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-29a Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-29b-1 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-29c Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-30a Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-30b Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-30d Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-30e Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-7-1 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-7-2 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-7-3 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-9-1 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-9-2 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-92a-1 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-92a-2 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-92b Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-9-3 Schizophrenia 17326821 downregulation tissue_expression_down hsa-mir-16-1 Autoimmune Diseases [unspecific] 17351108 "New Zealand black (NZB) mice (NZB) tissue sourcesof RNA showed a decrease in miR-16 in the spleen; however, theNZB kidney was not decreased in miR-16 expression compared withthe control strain expression. In addition, the NZB-derivedmalignant B-cell line, LNC, had an even greater decreased expressionof miR-16 compared with C57Bl6 spleen." tissue_expression_down hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 17351108 "New Zealand black (NZB) mice (NZB) tissue sourcesof RNA showed a decrease in miR-16 in the spleen; however, theNZB kidney was not decreased in miR-16 expression compared withthe control strain expression. In addition, the NZB-derivedmalignant B-cell line, LNC, had an even greater decreased expressionof miR-16 compared with C57Bl6 spleen." tissue_expression_down hsa-mir-16-2 Autoimmune Diseases [unspecific] 17351108 "New Zealand black (NZB) mice (NZB) tissue sourcesof RNA showed a decrease in miR-16 in the spleen; however, theNZB kidney was not decreased in miR-16 expression compared withthe control strain expression. In addition, the NZB-derivedmalignant B-cell line, LNC, had an even greater decreased expressionof miR-16 compared with C57Bl6 spleen." tissue_expression_down hsa-mir-16-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 17351108 "New Zealand black (NZB) mice (NZB) tissue sourcesof RNA showed a decrease in miR-16 in the spleen; however, theNZB kidney was not decreased in miR-16 expression compared withthe control strain expression. In addition, the NZB-derivedmalignant B-cell line, LNC, had an even greater decreased expressionof miR-16 compared with C57Bl6 spleen." tissue_expression_down hsa-mir-125b "Carcinoma, Thyroid, Anaplastic" 17563749 "The overexpression of these four miRs in two human ATC-derived cell lines suggests a critical role of miR-125b and miR-26a downregulation in thyroid carcinogenesis, since a cell growth inhibition was achieved." tissue_expression_down hsa-mir-26a "Carcinoma, Thyroid, Anaplastic" 17563749 "The overexpression of these four miRs in two human ATC-derived cell lines suggests a critical role of miR-125b and miR-26a downregulation in thyroid carcinogenesis, since a cell growth inhibition was achieved." tissue_expression_down hsa-mir-107 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-130b Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-135a-1 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-135a-2 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-136 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-148a Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-150 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-16-1 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-16-2 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-17 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-182 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-186 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-192 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-19b-1 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-19b-2 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-218-1 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-218-2 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-22 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-23b Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-24-1 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-24-2 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-27a Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-299 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-302b Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-302c Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-30a Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-30b Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-30c-1 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-30c-2 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-30e Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-325 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-339 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-342 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-452 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-494 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-497 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-499a Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-507 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-512-1 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-512-2 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-515-1 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-515-2 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-520a Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-520b Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-520d Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-520e Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-520f Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-520g Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-520h Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-523 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-526a-1 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-526a-2 Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-526b Heart Failure 17606841 downregulated tissue_expression_down hsa-mir-125b-1 Atopic Dermatitis 17622355 The level of this miRNA significantly (p<0.001 for both) decreased both in psoriasis and atopic eczema. tissue_expression_down hsa-mir-125b-1 Psoriasis 17622355 The level of this miRNA significantly (p<0.001 for both) decreased both in psoriasis and atopic eczema. tissue_expression_down hsa-mir-125b-2 Atopic Dermatitis 17622355 The level of this miRNA significantly (p<0.001 for both) decreased both in psoriasis and atopic eczema. tissue_expression_down hsa-mir-125b-2 Psoriasis 17622355 The level of this miRNA significantly (p<0.001 for both) decreased both in psoriasis and atopic eczema. tissue_expression_down hsa-mir-125b-1 Ovarian Neoplasms 17875710 "The most significantly overexpressed miRNAs were miR-200a, miR-141, miR-200c, and miR-200b, whereas miR-199a, miR-140, miR-145, and miR-125b1 were among the most down-modulated miRNAs." tissue_expression_down hsa-mir-1-1 Musculoskeletal Abnormalities [unspecific] 17917533 "Studies performed to determine whether skeletal muscle hypertrophy affects miRNA expression showed that miR-1 and miR-133 were decreased, suggesting that these muscle-specific miRNAs may contribute to regulating the initial response of skeletal muscle to functional overload." tissue_expression_down hsa-mir-1-2 Musculoskeletal Abnormalities [unspecific] 17917533 "Studies performed to determine whether skeletal muscle hypertrophy affects miRNA expression showed that miR-1 and miR-133 were decreased, suggesting that these muscle-specific miRNAs may contribute to regulating the initial response of skeletal muscle to functional overload." tissue_expression_down hsa-mir-133a-1 Musculoskeletal Abnormalities [unspecific] 17917533 "Studies performed to determine whether skeletal muscle hypertrophy affects miRNA expression showed that miR-1 and miR-133 were decreased, suggesting that these muscle-specific miRNAs may contribute to regulating the initial response of skeletal muscle to functional overload." tissue_expression_down hsa-mir-133a-2 Musculoskeletal Abnormalities [unspecific] 17917533 "Studies performed to determine whether skeletal muscle hypertrophy affects miRNA expression showed that miR-1 and miR-133 were decreased, suggesting that these muscle-specific miRNAs may contribute to regulating the initial response of skeletal muscle to functional overload." tissue_expression_down hsa-mir-206 Musculoskeletal Abnormalities [unspecific] 17917533 Studies to evaluate the role of miRNAs in muscular dystrophy showed a dramatic increase in miR-206 expression in the diaphragm of the mdx mouse. tissue_expression_down hsa-let-7c "Carcinoma, Hepatocellular" 18006136 These mice do not exhibit downregulation of let-7c gene expression thus forming the basis for the resistance to hepatocellular carcinogenesis. tissue_expression_down hsa-mir-1 Retinitis Pigmentosa 18034880 "Expression of miR-1 and miR-133 decreased by more than 2.5-fold (P < 0.001), whereas expression of miR-96 and miR-183 increased by more than 3-fold (P < 0.001) in Pro347Ser retinas, as validated by qPCR." tissue_expression_down hsa-mir-133 Retinitis Pigmentosa 18034880 "Expression of miR-1 and miR-133 decreased by more than 2.5-fold (P < 0.001), whereas expression of miR-96 and miR-183 increased by more than 3-fold (P < 0.001) in Pro347Ser retinas, as validated by qPCR." tissue_expression_down hsa-mir-143 "Carcinoma, Rectal" 18196926 "Expression levels of analyzed miRNAs significantly differed among tumors and adjacent non-tumor tissues: miR-21 (p = 0.0001) and miR-31 (p = 0.0006) were upregulated, and miR-143 (p = 0.011) and miR-145 (p = 0.003) were downregulated in tumors." tissue_expression_down hsa-mir-145 "Carcinoma, Rectal" 18196926 "Expression levels of analyzed miRNAs significantly differed among tumors and adjacent non-tumor tissues: miR-21 (p = 0.0001) and miR-31 (p = 0.0006) were upregulated, and miR-143 (p = 0.011) and miR-145 (p = 0.003) were downregulated in tumors." tissue_expression_down hsa-mir-107 Alzheimer Disease 18234899 downregulated tissue_expression_down hsa-mir-145 "Carcinoma, Hepatocellular" 18307259 "miR-122, miR-100, and miR-10a were overexpressed whereas miR-198 and miR-145 were up to 5-fold down-regulated in hepatic tumors compared to normal liver parenchyma." tissue_expression_down hsa-mir-198 "Carcinoma, Hepatocellular" 18307259 "miR-122, miR-100, and miR-10a were overexpressed whereas miR-198 and miR-145 were up to 5-fold down-regulated in hepatic tumors compared to normal liver parenchyma." tissue_expression_down hsa-mir-96 "Carcinoma, Hepatocellular" 18433021 "miR-96 was overexpressed in HBV tumors, and miR-126* was down-regulated in alcohol-related hepatocellular carcinoma." tissue_expression_down hsa-let-7b Ovarian Neoplasms 18451233 lower tissue_expression_down hsa-mir-106a Retinal Neovascularization 18500251 decreased tissue_expression_down hsa-mir-214 Retinal Neovascularization 18500251 decreased tissue_expression_down hsa-mir-424 Retinal Neovascularization 18500251 decreased tissue_expression_down hsa-mir-221 Ovarian Neoplasms 18560586 "we identify several miRNAs aberrantly expressed in human ovarian cancer tissues and cell lines. miR-221 stands out as a highly elevated miRNA in ovarian cancer, while miR-21 and several members of the let-7 family are found downregulated." tissue_expression_down hsa-mir-126 Urinary Bladder Cancer 18596939 miR-126: downregulated tissue_expression_down hsa-mir-143 Urinary Bladder Cancer 18596939 miR-143: downregulated tissue_expression_down hsa-mir-145 Urinary Bladder Cancer 18596939 miR-145: downregulated tissue_expression_down hsa-mir-15a "Carcinoma, Pancreatic" 18665421 "In addition, when analyzed according to specific cancer phenotypes, miR-15a and miR-16 show a significant downregulation in canine ductal carcinomas while miRsR-181b, -21, -29b, and let-7f show a significant upregulation in canine tubular papillary carcinomas." tissue_expression_down hsa-mir-16 "Carcinoma, Pancreatic" 18665421 "In addition, when analyzed according to specific cancer phenotypes, miR-15a and miR-16 show a significant downregulation in canine ductal carcinomas while miRsR-181b, -21, -29b, and let-7f show a significant upregulation in canine tubular papillary carcinomas." tissue_expression_down hsa-mir-499a Head And Neck Neoplasms 18798260 miR-499: underexpressed tissue_expression_down hsa-let-7c "Lymphoma, Burkitt" 18802929 "In particular, down-regulation of hsa-let-7c was observed in BL cases, compared to normal controls." tissue_expression_down hsa-mir-145 Prostate Neoplasms 18949015 miR-145: down-regulated tissue_expression_down hsa-mir-221 Prostate Neoplasms 18949015 miR-221: down-regulated tissue_expression_down hsa-mir-222 Prostate Neoplasms 18949015 miR-222: down-regulated tissue_expression_down hsa-mir-23b Prostate Neoplasms 18949015 miR-23b: down-regulated tissue_expression_down hsa-mir-127 Ovarian Neoplasms 18954897 miR-127: under-expression tissue_expression_down hsa-mir-155 Ovarian Neoplasms 18954897 miR-155: under-expression tissue_expression_down hsa-mir-99b Ovarian Neoplasms 18954897 miR-99b: under-expression tissue_expression_down hsa-mir-31 Medulloblastoma 18973228 miR-31: downregulated in all MBs tissue_expression_down hsa-mir-1-1 Heart Failure 19059107 miR-1: decreased expression tissue_expression_down hsa-mir-1-2 Heart Failure 19059107 miR-1: decreased expression tissue_expression_down hsa-mir-133a-1 Heart Failure 19059107 miR-133a: decreased expression tissue_expression_down hsa-mir-133a-2 Heart Failure 19059107 miR-133a: decreased expression tissue_expression_down hsa-mir-133b Heart Failure 19059107 miR-133b: decreased expression tissue_expression_down hsa-mir-141 Endometriosis 19074548 miR-141: downregulated tissue_expression_down hsa-mir-142 Endometriosis 19074548 miR-142-3p: downregulated tissue_expression_down hsa-mir-196b Endometriosis 19074548 miR-196b: downregulated tissue_expression_down hsa-mir-200a Endometriosis 19074548 miR-200a: downregulated tissue_expression_down hsa-mir-200b Endometriosis 19074548 miR-200b: downregulated tissue_expression_down hsa-mir-20a Endometriosis 19074548 miR-20a: downregulated tissue_expression_down hsa-mir-34c Endometriosis 19074548 miR-34c: downregulated tissue_expression_down hsa-mir-424 Endometriosis 19074548 miR-424: downregulated tissue_expression_down hsa-mir-193b "Adenocarcinoma, Endometrial" 19077565 miR-193b: downregulated tissue_expression_down hsa-mir-204 "Adenocarcinoma, Endometrial" 19077565 miR-204: downregulated tissue_expression_down hsa-mir-99b "Adenocarcinoma, Endometrial" 19077565 miR-99b: downregulated tissue_expression_down hsa-mir-129-1 Gastric Neoplasms 19148490 miR-129: downregulated in undifferentiated gastric cancer tissue_expression_down hsa-mir-129-2 Gastric Neoplasms 19148490 miR-129: downregulated in undifferentiated gastric cancer tissue_expression_down hsa-mir-148a Gastric Neoplasms 19148490 miR-148: downregulated in undifferentiated gastric cancer tissue_expression_down hsa-mir-148b Gastric Neoplasms 19148490 miR-148: downregulated in undifferentiated gastric cancer tissue_expression_down hsa-let-7a-1 Digestive System Neoplasms 19156147 let-7a: downregulation tissue_expression_down hsa-let-7a-2 Digestive System Neoplasms 19156147 let-7a: downregulation tissue_expression_down hsa-let-7a-3 Digestive System Neoplasms 19156147 let-7a: downregulation tissue_expression_down hsa-let-7b Digestive System Neoplasms 19156147 let-7b: downregulation tissue_expression_down hsa-let-7c Digestive System Neoplasms 19156147 let-7c: downregulation tissue_expression_down hsa-let-7d Digestive System Neoplasms 19156147 let-7d: downregulation tissue_expression_down hsa-let-7e Digestive System Neoplasms 19156147 let-7e: downregulation tissue_expression_down hsa-let-7f-1 Digestive System Neoplasms 19156147 let-7f: downregulation tissue_expression_down hsa-let-7f-2 Digestive System Neoplasms 19156147 let-7f: downregulation tissue_expression_down hsa-let-7g Digestive System Neoplasms 19156147 let-7g: downregulation tissue_expression_down hsa-let-7i Digestive System Neoplasms 19156147 let-7i: downregulation tissue_expression_down hsa-mir-373 Prostate Neoplasms 19158933 "miR-373: MicroRNAs 373 and 520c Are Downregulated in Prostate Cancer, Suppress CD44" tissue_expression_down hsa-mir-520c Prostate Neoplasms 19158933 "miR-520c: MicroRNAs 373 and 520c Are Downregulated in Prostate Cancer, Suppress CD44" tissue_expression_down hsa-mir-181b-1 Astrocytoma 19159078 miR-181b: downregulation tissue_expression_down hsa-mir-181b-2 Astrocytoma 19159078 miR-181b: downregulation tissue_expression_down hsa-mir-143 Neoplasms [unspecific] 19175697 "The expression of a subset of miRs (e.g. miR-21 and miR-155) was found to be consistently up-regulated, whereas another subset of miRs (e.g.miR-143 and miR-145) was consistently down-regulated across different cancer types suggesting their involvement in regulating common cellular processes whose deregulation may lead to tumourigenesis." tissue_expression_down hsa-mir-145 Neoplasms [unspecific] 19175697 "The expression of a subset of miRs (e.g. miR-21 and miR-155) was found to be consistently up-regulated, whereas another subset of miRs (e.g.miR-143 and miR-145) was consistently down-regulated across different cancer types suggesting their involvement in regulating common cellular processes whose deregulation may lead to tumourigenesis." tissue_expression_down hsa-mir-133b Gastric Neoplasms 19175831 miR-133b: down-regulated tissue_expression_down hsa-mir-139 Gastric Neoplasms 19175831 miR-139-5p: down-regulated tissue_expression_down hsa-mir-195 Gastric Neoplasms 19175831 miR-195: down-regulated tissue_expression_down hsa-mir-31 Gastric Neoplasms 19175831 miR-31: down-regulated tissue_expression_down hsa-mir-378a Gastric Neoplasms 19175831 miR-378: down-regulated tissue_expression_down hsa-mir-497 Gastric Neoplasms 19175831 miR-497: down-regulated tissue_expression_down hsa-let-7d Head And Neck Neoplasms 19179615 let-7d: show lower expression levels relative to normal adjacent tissue tissue_expression_down hsa-mir-1-1 Head And Neck Neoplasms 19179615 miR-1: show lower expression levels relative to normal adjacent tissue tissue_expression_down hsa-mir-1-2 Head And Neck Neoplasms 19179615 miR-1: show lower expression levels relative to normal adjacent tissue tissue_expression_down hsa-mir-133a-1 Head And Neck Neoplasms 19179615 miR-133a: show lower expression levels relative to normal adjacent tissue tissue_expression_down hsa-mir-133a-2 Head And Neck Neoplasms 19179615 miR-133a: show lower expression levels relative to normal adjacent tissue tissue_expression_down hsa-mir-205 Head And Neck Neoplasms 19179615 miR-205: show lower expression levels relative to normal adjacent tissue tissue_expression_down hsa-mir-15a Hepatitis B Virus Infection 19187610 miR-15a: down-regulated tissue_expression_down hsa-mir-141 "Carcinoma, Renal Cell" 19228262 miR-141: down-regulated in malignant cancer than non-malignant one tissue_expression_down hsa-mir-200b "Carcinoma, Renal Cell" 19228262 miR-200b: down-regulated in malignant cancer than non-malignant one tissue_expression_down hsa-mir-200c "Carcinoma, Renal Cell" 19228262 miR-200c: down-regulated in malignant cancer than non-malignant one tissue_expression_down hsa-mir-363 "Carcinoma, Renal Cell" 19228262 miR-363: down-regulated in malignant cancer than non-malignant one tissue_expression_down hsa-mir-429 "Carcinoma, Renal Cell" 19228262 miR-429: down-regulated in malignant cancer than non-malignant one tissue_expression_down hsa-mir-514a-1 "Carcinoma, Renal Cell" 19228262 miR-514: down-regulated in malignant cancer than non-malignant one tissue_expression_down hsa-mir-514a-2 "Carcinoma, Renal Cell" 19228262 miR-514: down-regulated in malignant cancer than non-malignant one tissue_expression_down hsa-mir-514a-3 "Carcinoma, Renal Cell" 19228262 miR-514: down-regulated in malignant cancer than non-malignant one tissue_expression_down hsa-mir-205 Breast Neoplasms 19238171 miR-205: Suppress cell growth and invasion by target ErbB3 and VEGF-A tissue_expression_down hsa-let-7a-1 Kaposi Sarcoma 19252139 let-7a: down-regulated tissue_expression_down hsa-let-7a-1 "Lymphoma, Primary Effusion" 19252139 let-7a: down-regulated tissue_expression_down hsa-let-7a-2 Kaposi Sarcoma 19252139 let-7a: down-regulated tissue_expression_down hsa-let-7a-2 "Lymphoma, Primary Effusion" 19252139 let-7a: down-regulated tissue_expression_down hsa-let-7a-3 Kaposi Sarcoma 19252139 let-7a: down-regulated tissue_expression_down hsa-let-7a-3 "Lymphoma, Primary Effusion" 19252139 let-7a: down-regulated tissue_expression_down hsa-let-7b Kaposi Sarcoma 19252139 let-7b: down-regulated tissue_expression_down hsa-let-7b "Lymphoma, Primary Effusion" 19252139 let-7b: down-regulated tissue_expression_down hsa-let-7c Kaposi Sarcoma 19252139 let-7c: down-regulated tissue_expression_down hsa-let-7c "Lymphoma, Primary Effusion" 19252139 let-7c: down-regulated tissue_expression_down hsa-let-7d Kaposi Sarcoma 19252139 let-7d: down-regulated tissue_expression_down hsa-let-7d "Lymphoma, Primary Effusion" 19252139 let-7d: down-regulated tissue_expression_down hsa-let-7e Kaposi Sarcoma 19252139 let-7e: down-regulated tissue_expression_down hsa-let-7e "Lymphoma, Primary Effusion" 19252139 let-7e: down-regulated tissue_expression_down hsa-let-7f-1 Kaposi Sarcoma 19252139 let-7f: down-regulated tissue_expression_down hsa-let-7f-1 "Lymphoma, Primary Effusion" 19252139 let-7f: down-regulated tissue_expression_down hsa-let-7f-2 Kaposi Sarcoma 19252139 let-7f: down-regulated tissue_expression_down hsa-let-7f-2 "Lymphoma, Primary Effusion" 19252139 let-7f: down-regulated tissue_expression_down hsa-let-7g Kaposi Sarcoma 19252139 let-7g: down-regulated tissue_expression_down hsa-let-7g "Lymphoma, Primary Effusion" 19252139 let-7g: down-regulated tissue_expression_down hsa-let-7i Kaposi Sarcoma 19252139 let-7i: down-regulated tissue_expression_down hsa-let-7i "Lymphoma, Primary Effusion" 19252139 let-7i: down-regulated tissue_expression_down hsa-mir-221 Kaposi Sarcoma 19252139 miR-221: down-regulated tissue_expression_down hsa-mir-221 "Lymphoma, Primary Effusion" 19252139 miR-221: down-regulated tissue_expression_down hsa-mir-222 Kaposi Sarcoma 19252139 miR-222: down-regulated tissue_expression_down hsa-mir-222 "Lymphoma, Primary Effusion" 19252139 miR-222: down-regulated tissue_expression_down hsa-mir-98 Kaposi Sarcoma 19252139 miR-98: down-regulated tissue_expression_down hsa-mir-98 "Lymphoma, Primary Effusion" 19252139 miR-98: down-regulated tissue_expression_down hsa-let-7g Endotoxemia 19284987 "Data analysis revealed that five miRNAs consistently responded to LPS-infusion, four of which were down-regulated (miR-146b, miR-150, miR-342, and let-7g) and one was up-regulated (miR-143). The miR-150 and mir-342 response was confirmed by real-time PCR." tissue_expression_down hsa-mir-146b Endotoxemia 19284987 "Data analysis revealed that five miRNAs consistently responded to LPS-infusion, four of which were down-regulated (miR-146b, miR-150, miR-342, and let-7g) and one was up-regulated (miR-143). The miR-150 and mir-342 response was confirmed by real-time PCR." tissue_expression_down hsa-mir-150 Endotoxemia 19284987 "Data analysis revealed that five miRNAs consistently responded to LPS-infusion, four of which were down-regulated (miR-146b, miR-150, miR-342, and let-7g) and one was up-regulated (miR-143). The miR-150 and mir-342 response was confirmed by real-time PCR." tissue_expression_down hsa-mir-342 Endotoxemia 19284987 "Data analysis revealed that five miRNAs consistently responded to LPS-infusion, four of which were down-regulated (miR-146b, miR-150, miR-342, and let-7g) and one was up-regulated (miR-143). The miR-150 and mir-342 response was confirmed by real-time PCR." tissue_expression_down hsa-mir-143 Colorectal Carcinoma 19287964 miR-143: down-regualted tissue_expression_down hsa-mir-145 Colorectal Carcinoma 19287964 miR-145: down-regulated tissue_expression_down hsa-mir-125b Breast Neoplasms 19290006 "Compared with normal breast samples, a panel of miRs was consistently dysregulated in breast cancer, including earlier-reported breast cancer-related miRs, such as upregulated miR-21, miR-155, miR-191, and miR-196a, and downregulated miR-125b and miR-221." tissue_expression_down hsa-mir-221 Breast Neoplasms 19290006 "Compared with normal breast samples, a panel of miRs was consistently dysregulated in breast cancer, including earlier-reported breast cancer-related miRs, such as upregulated miR-21, miR-155, miR-191, and miR-196a, and downregulated miR-125b and miR-221." tissue_expression_down hsa-mir-122a Primary Biliary Cirrhosis 19345069 A total of 35 independent miRNAs were found to be differentially expressed in PBC (p < 0.001).Quantitative PCR was employed to validate down-regulation of microRNA-122a (miR-122a) and miR-26a and the increased expression of miR-328 and miR-299-5p. tissue_expression_down hsa-mir-26a Primary Biliary Cirrhosis 19345069 A total of 35 independent miRNAs were found to be differentially expressed in PBC (p < 0.001).Quantitative PCR was employed to validate down-regulation of microRNA-122a (miR-122a) and miR-26a and the increased expression of miR-328 and miR-299-5p. tissue_expression_down hsa-mir-17 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 19347736 miR-17-5p: down-regulated tissue_expression_down hsa-mir-29a "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 19347736 miR-29: down-regulated tissue_expression_down hsa-mir-29b-1 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 19347736 miR-29: down-regulated tissue_expression_down hsa-mir-29b-2 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 19347736 miR-29: down-regulated tissue_expression_down hsa-mir-29c "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 19347736 miR-29: down-regulated tissue_expression_down hsa-mir-34a "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 19347736 miR-34a: down-regulated tissue_expression_down hsa-let-7a-1 Salivary Gland Neoplasms 19347935 let-7a: down-regulated tissue_expression_down hsa-let-7a-2 Salivary Gland Neoplasms 19347935 let-7a: down-regulated tissue_expression_down hsa-let-7a-3 Salivary Gland Neoplasms 19347935 let-7a: down-regulated tissue_expression_down hsa-mir-144 Salivary Gland Neoplasms 19347935 miR-144: down-regulated tissue_expression_down hsa-mir-20b Salivary Gland Neoplasms 19347935 miR-20b: down-regulated tissue_expression_down hsa-mir-375 Salivary Gland Neoplasms 19347935 miR-375: down-regulated tissue_expression_down hsa-mir-106b "Carcinoma, Adrenocortical" 19351815 miR-106b: down-regulated tissue_expression_down hsa-mir-139 "Carcinoma, Adrenocortical" 19351815 miR-139: down-regulated tissue_expression_down hsa-mir-148a "Carcinoma, Adrenocortical" 19351815 miR-148a: down-regulated tissue_expression_down hsa-mir-196a-1 "Carcinoma, Adrenocortical" 19351815 miR-196a: down-regulated tissue_expression_down hsa-mir-196a-2 "Carcinoma, Adrenocortical" 19351815 miR-196a: down-regulated tissue_expression_down hsa-mir-210 "Carcinoma, Adrenocortical" 19351815 miR-210: down-regulated tissue_expression_down hsa-mir-301a "Carcinoma, Adrenocortical" 19351815 miR-301: down-regulated tissue_expression_down hsa-mir-301b "Carcinoma, Adrenocortical" 19351815 miR-301: down-regulated tissue_expression_down hsa-mir-376a-1 "Carcinoma, Adrenocortical" 19351815 miR-376: down-regulated tissue_expression_down hsa-mir-376a-2 "Carcinoma, Adrenocortical" 19351815 miR-376: down-regulated tissue_expression_down hsa-mir-376b "Carcinoma, Adrenocortical" 19351815 miR-376: down-regulated tissue_expression_down hsa-mir-376c "Carcinoma, Adrenocortical" 19351815 miR-376: down-regulated tissue_expression_down hsa-mir-424 "Carcinoma, Adrenocortical" 19351815 miR-424: down-regulated tissue_expression_down hsa-mir-484 "Carcinoma, Adrenocortical" 19351815 miR-484: down-regulated tissue_expression_down hsa-mir-491 "Carcinoma, Adrenocortical" 19351815 miR-491: down-regulated tissue_expression_down hsa-mir-1-1 Hepatitis C Virus Infection 19360909 miR-1: down-regulated tissue_expression_down hsa-mir-1-2 Hepatitis C Virus Infection 19360909 miR-1: down-regulated tissue_expression_down hsa-mir-122 "Carcinoma, Hepatocellular" 19360909 miR-122: be decreased in HCC compared to non-tumoral tissue tissue_expression_down hsa-mir-145 "Carcinoma, Hepatocellular" 19360909 miR-145: be decreased in HCC compared to non-tumoral tissue tissue_expression_down hsa-mir-15a Liver Diseases [unspecific] 19360909 miR-15a: decreased tissue_expression_down hsa-mir-196a-1 Hepatitis C Virus Infection 19360909 miR-196: down-regulated tissue_expression_down hsa-mir-196a-2 Hepatitis C Virus Infection 19360909 miR-196: down-regulated tissue_expression_down hsa-mir-196b Hepatitis C Virus Infection 19360909 miR-196: down-regulated tissue_expression_down hsa-mir-198 "Carcinoma, Hepatocellular" 19360909 miR-198: up to five-fold down-regulated in hepatic tumors compared to normal liver parenchyma tissue_expression_down hsa-mir-199a-1 "Carcinoma, Hepatocellular" 19360909 miR-199a: be decreased in HCC compared to non-tumoral tissue tissue_expression_down hsa-mir-199a-2 "Carcinoma, Hepatocellular" 19360909 miR-199a: be decreased in HCC compared to non-tumoral tissue tissue_expression_down hsa-mir-296 Hepatitis C Virus Infection 19360909 miR-296: down-regulated tissue_expression_down hsa-mir-30a Hepatitis C Virus Infection 19360909 miR-30: down-regulated tissue_expression_down hsa-mir-30b Hepatitis C Virus Infection 19360909 miR-30: down-regulated tissue_expression_down hsa-mir-30c-1 Hepatitis C Virus Infection 19360909 miR-30: down-regulated tissue_expression_down hsa-mir-30c-2 Hepatitis C Virus Infection 19360909 miR-30: down-regulated tissue_expression_down hsa-mir-30d Hepatitis C Virus Infection 19360909 miR-30: down-regulated tissue_expression_down hsa-mir-431 Hepatitis C Virus Infection 19360909 miR-431: down-regulated tissue_expression_down hsa-mir-448 Hepatitis C Virus Infection 19360909 miR-448: down-regulated tissue_expression_down hsa-mir-141 Gastric Neoplasms 19363643 miR-141: significantly down-regulated in gastric cancer tissue_expression_down hsa-mir-125b Bladder Neoplasms 19378336 "We identified a subset of 7 miRNAs (miR-145, miR-30a-3p, miR-133a, miR-133b, miR-195, miR-125b and miR-199a*) that were significantly downregulated in BCs." tissue_expression_down hsa-mir-133a Bladder Neoplasms 19378336 "We identified a subset of 7 miRNAs (miR-145, miR-30a-3p, miR-133a, miR-133b, miR-195, miR-125b and miR-199a*) that were significantly downregulated in BCs." tissue_expression_down hsa-mir-133b Bladder Neoplasms 19378336 "We identified a subset of 7 miRNAs (miR-145, miR-30a-3p, miR-133a, miR-133b, miR-195, miR-125b and miR-199a*) that were significantly downregulated in BCs." tissue_expression_down hsa-mir-145 Bladder Neoplasms 19378336 "We identified a subset of 7 miRNAs (miR-145, miR-30a-3p, miR-133a, miR-133b, miR-195, miR-125b and miR-199a*) that were significantly downregulated in BCs." tissue_expression_down hsa-mir-195 Bladder Neoplasms 19378336 "We identified a subset of 7 miRNAs (miR-145, miR-30a-3p, miR-133a, miR-133b, miR-195, miR-125b and miR-199a*) that were significantly downregulated in BCs." tissue_expression_down hsa-mir-199a Bladder Neoplasms 19378336 "We identified a subset of 7 miRNAs (miR-145, miR-30a-3p, miR-133a, miR-133b, miR-195, miR-125b and miR-199a*) that were significantly downregulated in BCs." tissue_expression_down hsa-mir-30a Bladder Neoplasms 19378336 "We identified a subset of 7 miRNAs (miR-145, miR-30a-3p, miR-133a, miR-133b, miR-195, miR-125b and miR-199a*) that were significantly downregulated in BCs." tissue_expression_down hsa-mir-1 Essential Thrombocythemia 19497108 Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a. tissue_expression_down hsa-mir-133a Essential Thrombocythemia 19497108 Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a. tissue_expression_down hsa-mir-141 Ovarian Neoplasms 19501389 "miR-200b-429 may be used as a prognostic marker for ovarian cancer outcome, and low-level expression of miR-200 miRNAs in this cluster predicts poor survival." tissue_expression_down hsa-mir-200a Ovarian Neoplasms 19501389 "miR-200b-429 may be used as a prognostic marker for ovarian cancer outcome, and low-level expression of miR-200 miRNAs in this cluster predicts poor survival." tissue_expression_down hsa-mir-200b Ovarian Neoplasms 19501389 "miR-200b-429 may be used as a prognostic marker for ovarian cancer outcome, and low-level expression of miR-200 miRNAs in this cluster predicts poor survival." tissue_expression_down hsa-mir-200c Ovarian Neoplasms 19501389 "miR-200b-429 may be used as a prognostic marker for ovarian cancer outcome, and low-level expression of miR-200 miRNAs in this cluster predicts poor survival." tissue_expression_down hsa-mir-429 Ovarian Neoplasms 19501389 "miR-200b-429 may be used as a prognostic marker for ovarian cancer outcome, and low-level expression of miR-200 miRNAs in this cluster predicts poor survival." tissue_expression_down hsa-mir-433 Gastrointestinal Neoplasms 19531230 Down-regulated miR-9 and miR-433 in human gastric carcinoma. tissue_expression_down hsa-mir-9 Gastrointestinal Neoplasms 19531230 Down-regulated miR-9 and miR-433 in human gastric carcinoma. tissue_expression_down hsa-mir-214 Adrenal Cortex Neoplasms 19546168 significantly lower expressed tissue_expression_down hsa-mir-183 Fatty Liver [unspecific] 19572984 down-regulated after Lieber-DeCarli ; tissue_expression_down hsa-mir-122 Melanoma 19578755 down-regulated tissue_expression_down hsa-mir-146b Melanoma 19578755 down-regulated tissue_expression_down hsa-mir-155 Melanoma 19578755 down-regulated tissue_expression_down hsa-mir-221 Prostate Neoplasms 19585579 miR-221:Expression of microRNA-221 is progressively reduced in aggressive prostate cancer and metastasis tissue_expression_down hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 19591824 "The microRNAs miR-15a and miR-16-1 are downregulated in multiple tumor types and are frequently deleted in chronic lymphocytic leukemia (CLL), myeloma and mantle cell lymphoma." tissue_expression_down hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 19591824 "The microRNAs miR-15a and miR-16-1 are downregulated in multiple tumor types and are frequently deleted in chronic lymphocytic leukemia (CLL), myeloma and mantle cell lymphoma." tissue_expression_down hsa-mir-155 Lung Neoplasms 19597153 down-regulated miR tissue_expression_down hsa-mir-17 Gastric Neoplasms 19598010 miR-17-92a cluster; expression lwere significantly lower than non-cancer tissue; may help to clarify the molecular mechanisms; may be a novel diagnostic biomarker tissue_expression_down hsa-mir-18a Gastric Neoplasms 19598010 miR-17-92a cluster; expression lwere significantly lower than non-cancer tissue; may help to clarify the molecular mechanisms; may be a novel diagnostic biomarker tissue_expression_down hsa-mir-19a Gastric Neoplasms 19598010 miR-17-92a cluster; expression lwere significantly lower than non-cancer tissue; may help to clarify the molecular mechanisms; may be a novel diagnostic biomarker tissue_expression_down hsa-mir-142 Lung Neoplasms 19618089 "miR-34c, miR-145, or miR-142-5p expression markedly diminished proliferation of lung cancer cell lines, clinical implications discussed" tissue_expression_down hsa-mir-145 Lung Neoplasms 19618089 "miR-34c, miR-145, or miR-142-5p expression markedly diminished proliferation of lung cancer cell lines, clinical implications discussed" tissue_expression_down hsa-mir-18b Lung Neoplasms 19618089 "miR-34c, miR-145, or miR-142-5p expression markedly diminished proliferation of lung cancer cell lines, clinical implications discussed" tissue_expression_down hsa-mir-133b Pancreatic Neoplasms 19654291 "downregulated, Up-regulation leads to the reversal of EMT" tissue_expression_down hsa-mir-182 Breast Neoplasms 19665978 downregulated in human BCSCs tissue_expression_down hsa-mir-183 Breast Neoplasms 19665978 downregulated in human BCSCs tissue_expression_down hsa-mir-200a Breast Neoplasms 19665978 downregulated in human BCSCs tissue_expression_down hsa-mir-429 Breast Neoplasms 19665978 downregulated in human BCSCs tissue_expression_down hsa-mir-96 Breast Neoplasms 19665978 downregulated in human BCSCs tissue_expression_down hsa-mir-143 Prostate Neoplasms 19671871 "Although miR-143 and miR-145 are highly expressed in normal tissues, they are significantly down-regulated in prostate cancer cells. " tissue_expression_down hsa-mir-145 Prostate Neoplasms 19671871 "Although miR-143 and miR-145 are highly expressed in normal tissues, they are significantly down-regulated in prostate cancer cells. " tissue_expression_down hsa-mir-145 Neoplasms [unspecific] 19676045 down-regulated tissue_expression_down hsa-mir-149 Neoplasms [unspecific] 19676045 down-regulated tissue_expression_down hsa-mir-182 Neoplasms [unspecific] 19676045 down-regulated tissue_expression_down hsa-mir-184 Neoplasms [unspecific] 19676045 down-regulated tissue_expression_down hsa-mir-205 Neoplasms [unspecific] 19676045 down-regulated tissue_expression_down hsa-mir-221 Neoplasms [unspecific] 19676045 down-regulated tissue_expression_down hsa-mir-222 Neoplasms [unspecific] 19676045 down-regulated tissue_expression_down hsa-mir-31 Neoplasms [unspecific] 19676045 down-regulated tissue_expression_down hsa-mir-499a Lymphoma 19690137 "deregulated, hypermutations" tissue_expression_down hsa-mir-148a Hepatoblastoma 19701500 downregulated tissue_expression_down hsa-mir-122 "Carcinoma, Hepatocellular" 19711427 down-regulation at early stage tissue_expression_down hsa-mir-155 "Carcinoma, Hepatocellular" 19711427 "Real-time reverse transcription polymerase chain reaction (RT-PCR) analysis demonstrated up-regulation of oncogenic miR-155, miR-221/222, and miR-21 and down-regulation of the most abundant liver-specific miR-122 at early stages of hepatocarcinogenesis." tissue_expression_down hsa-mir-21 "Carcinoma, Hepatocellular" 19711427 "Real-time reverse transcription polymerase chain reaction (RT-PCR) analysis demonstrated up-regulation of oncogenic miR-155, miR-221/222, and miR-21 and down-regulation of the most abundant liver-specific miR-122 at early stages of hepatocarcinogenesis." tissue_expression_down hsa-mir-221 "Carcinoma, Hepatocellular" 19711427 "Real-time reverse transcription polymerase chain reaction (RT-PCR) analysis demonstrated up-regulation of oncogenic miR-155, miR-221/222, and miR-21 and down-regulation of the most abundant liver-specific miR-122 at early stages of hepatocarcinogenesis." tissue_expression_down hsa-mir-222 "Carcinoma, Hepatocellular" 19711427 "Real-time reverse transcription polymerase chain reaction (RT-PCR) analysis demonstrated up-regulation of oncogenic miR-155, miR-221/222, and miR-21 and down-regulation of the most abundant liver-specific miR-122 at early stages of hepatocarcinogenesis." tissue_expression_down hsa-mir-140 Osteoarthritis 19714579 down-regulated IL-1beta-induced ADAMTS5 tissue_expression_down hsa-mir-16-1 Prostate Neoplasms 19738602 "microRNA (miR)-16, which is expressed at lower levels in prostate cancer cells, affects the proliferation of human prostate cancer cell lines both in vitro and in vivo" tissue_expression_down hsa-mir-16-2 Prostate Neoplasms 19738602 "microRNA (miR)-16, which is expressed at lower levels in prostate cancer cells, affects the proliferation of human prostate cancer cell lines both in vitro and in vivo" tissue_expression_down hsa-mir-1 Lung Neoplasms 19748927 "miR-21, mir-31, miR-130a, miR-146b and miR-377 were consistently upregulated, whereas miR-1 and miR-143 were downregulated in lung tumors relative to normal lungs." tissue_expression_down hsa-mir-143 Lung Neoplasms 19748927 "miR-21, mir-31, miR-130a, miR-146b and miR-377 were consistently upregulated, whereas miR-1 and miR-143 were downregulated in lung tumors relative to normal lungs." tissue_expression_down hsa-mir-203 Squamous Cell Carcinoma 19789312 "In adenocarcinoma patients, miR-21, miR-223, miR-192, and miR-194 expression was elevated, whereas miR-203 expression was reduced in cancerous compared with noncancerous tissue." tissue_expression_down hsa-mir-34a Melanoma 19830692 "miR-34a:MiR-15b and miR-210 were significantly upregulated, miR-34a was significantly downregulated in melanomas" tissue_expression_down hsa-mir-200b Adrenal Cortex Neoplasms 19849700 down-regulated tissue_expression_down hsa-mir-203 Adrenal Cortex Neoplasms 19849700 down-regulated tissue_expression_down hsa-mir-218 Gastrointestinal Neoplasms 19890957 "miR-218 expression was reduced significantly in gastric cancer tissues, in H. pylori-infected gastric mucosa, and in H. pylori-infected AGS cells." tissue_expression_down hsa-mir-10b "Adenocarcinoma, Endometrial" 19891660 down-regulated tissue_expression_down hsa-mir-152 "Adenocarcinoma, Endometrial" 19891660 down-regulated tissue_expression_down hsa-mir-145 Bladder Neoplasms 19915607 Our data indicate that reduction in miR-145 expression may provide bladder cancer cells with a selective advantage by inhibition of cell death otherwise triggered in malignant cells. tissue_expression_down hsa-mir-128-1 Glioblastoma 19941032 "miR-128:Micro-RNA-128 (miRNA-128) down-regulation in glioblastoma targets ARP5 (ANGPTL6), Bmi-1 and E2F-3a, key regulators of brain cell proliferation" tissue_expression_down hsa-mir-128-2 Glioblastoma 19941032 "miR-128:Micro-RNA-128 (miRNA-128) down-regulation in glioblastoma targets ARP5 (ANGPTL6), Bmi-1 and E2F-3a, key regulators of brain cell proliferation" tissue_expression_down hsa-mir-133b Breast Neoplasms 19946373 downregulated tissue_expression_down hsa-mir-133b Colon Neoplasms 19946373 downregulated tissue_expression_down hsa-mir-133b Liver Neoplasms 19946373 downregulated tissue_expression_down hsa-mir-133b Lung Neoplasms 19946373 downregulated tissue_expression_down hsa-mir-133b Lymphoma 19946373 downregulated tissue_expression_down hsa-mir-133b Ovarian Neoplasms 19946373 downregulated tissue_expression_down hsa-mir-133b Prostate Neoplasms 19946373 downregulated tissue_expression_down hsa-mir-133b Testicular Neoplasms 19946373 downregulated tissue_expression_down hsa-mir-486 Breast Neoplasms 19946373 miR-486-5p: downregulated tissue_expression_down hsa-mir-486 Colon Neoplasms 19946373 miR-486-5p: downregulated tissue_expression_down hsa-mir-486 Liver Neoplasms 19946373 miR-486-5p: downregulated tissue_expression_down hsa-mir-486 Lung Neoplasms 19946373 miR-486-5p: downregulated tissue_expression_down hsa-mir-486 Lymphoma 19946373 miR-486-5p: downregulated tissue_expression_down hsa-mir-486 Ovarian Neoplasms 19946373 miR-486-5p: downregulated tissue_expression_down hsa-mir-486 Prostate Neoplasms 19946373 miR-486-5p: downregulated tissue_expression_down hsa-mir-486 Testicular Neoplasms 19946373 miR-486-5p: downregulated tissue_expression_down hsa-mir-130a Gastric Neoplasms 19948396 "different miRNAs have been found to predict sensitivity to anticancer treatment: miR-30c, miR-130a and miR-335 are downregulated in various chemoresistant cell lines, hsa-Let-7g and hsa-miR-181b are strongly associated with response to 5-fluorouracil-based antimetabolite S-1" tissue_expression_down hsa-mir-30c Gastric Neoplasms 19948396 "different miRNAs have been found to predict sensitivity to anticancer treatment: miR-30c, miR-130a and miR-335 are downregulated in various chemoresistant cell lines, hsa-Let-7g and hsa-miR-181b are strongly associated with response to 5-fluorouracil-based antimetabolite S-1" tissue_expression_down hsa-mir-335 Gastric Neoplasms 19948396 "different miRNAs have been found to predict sensitivity to anticancer treatment: miR-30c, miR-130a and miR-335 are downregulated in various chemoresistant cell lines, hsa-Let-7g and hsa-miR-181b are strongly associated with response to 5-fluorouracil-based antimetabolite S-1" tissue_expression_down hsa-mir-1826 Colon Neoplasms 19956872 "The down-regulations of miR-197, miR-191, miR-92a, miR-93, miR-222 and miR-1826, whose expression was significantly down-regulated in both cell lines after the treatment of one drug or in one cell line following exposure to either drug, were further validated." tissue_expression_down hsa-mir-191 Colon Neoplasms 19956872 "The down-regulations of miR-197, miR-191, miR-92a, miR-93, miR-222 and miR-1826, whose expression was significantly down-regulated in both cell lines after the treatment of one drug or in one cell line following exposure to either drug, were further validated." tissue_expression_down hsa-mir-197 Colon Neoplasms 19956872 "The down-regulations of miR-197, miR-191, miR-92a, miR-93, miR-222 and miR-1826, whose expression was significantly down-regulated in both cell lines after the treatment of one drug or in one cell line following exposure to either drug, were further validated." tissue_expression_down hsa-mir-222 Colon Neoplasms 19956872 "The down-regulations of miR-197, miR-191, miR-92a, miR-93, miR-222 and miR-1826, whose expression was significantly down-regulated in both cell lines after the treatment of one drug or in one cell line following exposure to either drug, were further validated." tissue_expression_down hsa-mir-92a Colon Neoplasms 19956872 "The down-regulations of miR-197, miR-191, miR-92a, miR-93, miR-222 and miR-1826, whose expression was significantly down-regulated in both cell lines after the treatment of one drug or in one cell line following exposure to either drug, were further validated." tissue_expression_down hsa-mir-93 Colon Neoplasms 19956872 "The down-regulations of miR-197, miR-191, miR-92a, miR-93, miR-222 and miR-1826, whose expression was significantly down-regulated in both cell lines after the treatment of one drug or in one cell line following exposure to either drug, were further validated." tissue_expression_down hsa-mir-195 Adrenal Cortex Neoplasms 19996210 miR-335 and miR-195 were significantly downregulated in adrenocortical carcinomas tissue_expression_down hsa-mir-483 Adrenal Cortex Neoplasms 19996210 miR-335 and miR-195 were significantly downregulated in adrenocortical carcinomas tissue_expression_down hsa-mir-320a Interstitial Cystitis 20008142 "demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels" tissue_expression_down hsa-mir-320b-1 Interstitial Cystitis 20008142 "demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels" tissue_expression_down hsa-mir-320b-2 Interstitial Cystitis 20008142 "demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels" tissue_expression_down hsa-mir-320c-1 Interstitial Cystitis 20008142 "demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels" tissue_expression_down hsa-mir-320c-2 Interstitial Cystitis 20008142 "demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels" tissue_expression_down hsa-mir-320d-1 Interstitial Cystitis 20008142 "demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels" tissue_expression_down hsa-mir-320d-2 Interstitial Cystitis 20008142 "demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels" tissue_expression_down hsa-mir-328 Interstitial Cystitis 20008142 "demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels" tissue_expression_down hsa-mir-449b Interstitial Cystitis 20008142 "demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels" tissue_expression_down hsa-mir-500a Interstitial Cystitis 20008142 "demonstrate a direct correlation between miR-449b, miR-500, miR-328, and miR-320 and a down-regulation of NK1R mRNA and/or protein levels" tissue_expression_down hsa-let-7g Gastric Neoplasms 20022810 low expression tissue_expression_down hsa-mir-433 Gastric Neoplasms 20022810 Low expression tissue_expression_down hsa-mir-153-1 Endometrial Neoplasms 20028871 "Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1" tissue_expression_down hsa-mir-153-2 Endometrial Neoplasms 20028871 "Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1" tissue_expression_down hsa-mir-182 Endometrial Neoplasms 20028871 "Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1" tissue_expression_down hsa-mir-183 Endometrial Neoplasms 20028871 "Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1" tissue_expression_down hsa-mir-186 Endometrial Neoplasms 20028871 "Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1" tissue_expression_down hsa-mir-27a Endometrial Neoplasms 20028871 "Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1" tissue_expression_down hsa-mir-27b Endometrial Neoplasms 20028871 "Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1" tissue_expression_down hsa-mir-9-1 Endometrial Neoplasms 20028871 "Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1" tissue_expression_down hsa-mir-9-2 Endometrial Neoplasms 20028871 "Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1" tissue_expression_down hsa-mir-9-3 Endometrial Neoplasms 20028871 "Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1" tissue_expression_down hsa-mir-96 Endometrial Neoplasms 20028871 "Expression of miR-9, miR-27, miR-96, miR-153, miR-182, miR-183, or miR-186, but not miR-29a, miR-128, miR-152, or miR-486 mimetics in HEC-1B cells was sufficient to significantly reduce the abundance of FOXO1" tissue_expression_down hsa-mir-133b Myocardial Infarction 20029200 downregulated tissue_expression_down hsa-let-7a-1 Ovarian Neoplasms 20035894 hsa-let-7a:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families tissue_expression_down hsa-let-7a-2 Ovarian Neoplasms 20035894 hsa-let-7a:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families tissue_expression_down hsa-let-7a-3 Ovarian Neoplasms 20035894 hsa-let-7a:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families tissue_expression_down hsa-let-7b Ovarian Neoplasms 20035894 hsa-let-7b:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families tissue_expression_down hsa-let-7c Ovarian Neoplasms 20035894 hsa-let-7c:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families tissue_expression_down hsa-let-7d Ovarian Neoplasms 20035894 hsa-let-7d:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families tissue_expression_down hsa-let-7e Ovarian Neoplasms 20035894 hsa-let-7e:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families tissue_expression_down hsa-let-7f-1 Ovarian Neoplasms 20035894 hsa-let-7f:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families tissue_expression_down hsa-let-7f-2 Ovarian Neoplasms 20035894 hsa-let-7f:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families tissue_expression_down hsa-let-7g Ovarian Neoplasms 20035894 hsa-let-7g:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families tissue_expression_down hsa-let-7i Ovarian Neoplasms 20035894 hsa-let-7i:The most frequently deregulated miRNAs are members of the let-7 and miR-200 families tissue_expression_down hsa-mir-34a Pancreatic Neoplasms 20037478 "Finally,restituted expression of miR-34a, a miRNA whose expression is frequently lost in PDAC cell lines, abrogates growth, demonstrating that the anti-proliferative activity of this miRNA is operative in PDAC." tissue_expression_down hsa-mir-378 Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_down hsa-mir-34b Ovarian Neoplasms 20145172 reduced expression of miR-34b*/c may be particularly important for progression to the most advanced stages tissue_expression_down hsa-mir-34c Ovarian Neoplasms 20145172 reduced expression of miR-34b*/c may be particularly important for progression to the most advanced stages tissue_expression_down hsa-mir-10a Neoplasms [unspecific] 20145181 downregulation tissue_expression_down hsa-mir-10a "Squamous Cell Carcinoma, Head and Neck" 20145181 downregulation tissue_expression_down hsa-mir-10b Neoplasms [unspecific] 20145181 downregulation tissue_expression_down hsa-mir-125b-1 Neoplasms [unspecific] 20145181 underexpression tissue_expression_down hsa-mir-125b-2 Neoplasms [unspecific] 20145181 underexpression tissue_expression_down hsa-mir-375 Neoplasms [unspecific] 20145181 underexpression tissue_expression_down hsa-mir-375 "Squamous Cell Carcinoma, Head and Neck" 20145181 underexpression tissue_expression_down hsa-mir-34c Prostate Neoplasms 20162671 miR-34c is down regulated in prostate cancer and exerts tumor suppressive functions tissue_expression_down hsa-mir-133a-1 Cardiovascular Diseases [unspecific] 20173049 miR-133a:NFATc4 is negatively regulated in miR-133a-mediated cardiomyocyte hypertrophic repression tissue_expression_down hsa-mir-126 Myocardial Infarction 20187981 we found that AMI is associated with altered miRNA expression level and the differentially expressed miRNAs may be novel biomarkers of AMI tissue_expression_down hsa-mir-31 Myocardial Infarction 20187981 we found that AMI is associated with altered miRNA expression level and the differentially expressed miRNAs may be novel biomarkers of AMI tissue_expression_down hsa-mir-499a Myocardial Infarction 20187981 miR-499-5p; we found that AMI is associated with altered miRNA expression level and the differentially expressed miRNAs may be novel biomarkers of AMI tissue_expression_down hsa-mir-375 Neoplasms [unspecific] 20215506 MicroRNA-375 is downregulated in gastric carcinomas tissue_expression_down hsa-mir-150 Polycythemia Vera 20218812 We observed that miR-451 up-regulation and miR-150 down-regulation are associated with progression of erythroid maturation in K562 cells. tissue_expression_down hsa-mir-106a Astrocytoma 20219352 "miR-106a:hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma" tissue_expression_down hsa-mir-137 Astrocytoma 20219352 miR-137:The down-regulation of hsa-miR-137 in astrocytomas was shown to be associated with advanced clinical stages of this disease tissue_expression_down hsa-mir-181b-1 Astrocytoma 20219352 "miR-181b:hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma" tissue_expression_down hsa-mir-181b-2 Astrocytoma 20219352 "miR-181b:hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma" tissue_expression_down hsa-let-7b "Carcinoma, Oral" 20232482 "Together, these data demonstrate that elevated expression levels of Dicer in oral cancer cells correlate with downregulation of let-7b and increased cell proliferation." tissue_expression_down hsa-mir-145 Breast Neoplasms 20331864 down-regulated in male breast cancer tissue_expression_down hsa-mir-497 Breast Neoplasms 20331864 down-regulated in male breast cancer tissue_expression_down hsa-mir-34a Choriocarcinoma 20351093 MicroRNA-34a suppresses invasion through down-regulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells tissue_expression_down hsa-mir-191 Melanoma 20357817 "Furthermore, low expression of miR-191 and high expression of miR-193b were associated with poor melanoma-specific survive" tissue_expression_down hsa-mir-193a Melanoma 20357817 "In melanomas, miR-193a, miR-338, and miR-565 were underexpressed in cases with a BRAF mutation." tissue_expression_down hsa-mir-338 Melanoma 20357817 "In melanomas, miR-193a, miR-338, and miR-565 were underexpressed in cases with a BRAF mutation." tissue_expression_down hsa-mir-143 "Carcinoma, Lung, Non-Small-Cell" 20363096 "miR-143:Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis" tissue_expression_down hsa-mir-143 Lung Neoplasms 20363096 "downregulated; Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis" tissue_expression_down hsa-mir-181a-2 "Carcinoma, Lung, Non-Small-Cell" 20363096 "miR-181a:Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis" tissue_expression_down hsa-mir-181a-2 Lung Neoplasms 20363096 "downregulated; Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis" tissue_expression_down hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 20363096 "miR-21:Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis" tissue_expression_down hsa-mir-145 Neoplasms [unspecific] 20370992 under-expressed tissue_expression_down hsa-mir-155 Neoplasms [unspecific] 20370992 under-expressed tissue_expression_down hsa-let-7a-1 Colorectal Adenocarcinoma 20413677 "let-7a:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-let-7a-2 Colorectal Adenocarcinoma 20413677 "let-7a:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-let-7a-3 Colorectal Adenocarcinoma 20413677 "let-7a:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-mir-143 Colorectal Adenocarcinoma 20413677 "miR-143:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-mir-145 Colorectal Adenocarcinoma 20413677 "miR-145:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-mir-16-1 Colorectal Adenocarcinoma 20413677 "miR-16:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-mir-16-2 Colorectal Adenocarcinoma 20413677 "miR-16:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-mir-191 Colorectal Adenocarcinoma 20413677 "miR-191:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-mir-192 Colorectal Adenocarcinoma 20413677 "miR-192:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-mir-196a-1 Colorectal Adenocarcinoma 20413677 "miR-196a:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-mir-196a-2 Colorectal Adenocarcinoma 20413677 "miR-196a:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-mir-215 Colorectal Adenocarcinoma 20413677 "miR-215:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-mir-26b Colorectal Adenocarcinoma 20413677 "miR-26b:nine(miR-192, -215, -26b, -143, -145, -191, -196a, -16, and let-7a) were under-expressed in CRC" tissue_expression_down hsa-mir-148a Gastrointestinal Neoplasms 20422307 MiR-148a:MiR-148a and miR-152 may be involved in the carcinogenesis of gastrointestinal cancers and might be potential biomarkers tissue_expression_down hsa-mir-152 Gastrointestinal Neoplasms 20422307 MiR-152:MiR-148a and miR-152 may be involved in the carcinogenesis of gastrointestinal cancers and might be potential biomarkers tissue_expression_down hsa-mir-103a-1 Neoplasms [unspecific] 20439436 "miR-103:hsa-miR-103/106 were downgraded in cancer, whereas hsa-miR-30 became most prominent" tissue_expression_down hsa-mir-103a-2 Neoplasms [unspecific] 20439436 "miR-103:hsa-miR-103/106 were downgraded in cancer, whereas hsa-miR-30 became most prominent" tissue_expression_down hsa-mir-106a Neoplasms [unspecific] 20439436 "miR-106:hsa-miR-103/106 were downgraded in cancer, whereas hsa-miR-30 became most prominent" tissue_expression_down hsa-mir-200c Melanoma 20442294 "miRNA-200c:miRNA-200c to be consistently downregulated in melanocytes, melanoma cell lines, and patient samples, whereas miRNA-205 and miRNA-23b were markedly reduced only in patient samples" tissue_expression_down hsa-mir-205 Melanoma 20442294 "miRNA-205:miRNA-200c to be consistently downregulated in melanocytes, melanoma cell lines, and patient samples, whereas miRNA-205 and miRNA-23b were markedly reduced only in patient samples" tissue_expression_down hsa-mir-23b Melanoma 20442294 "miRNA-23b:miRNA-200c to be consistently downregulated in melanocytes, melanoma cell lines, and patient samples, whereas miRNA-205 and miRNA-23b were markedly reduced only in patient samples" tissue_expression_down hsa-mir-34a Cervical Neoplasms 20442590 Reduced miR-34a expression in normal cervical tissues and cervical lesions with high-risk human papillomavirus infection. tissue_expression_down hsa-mir-17 "Lymphoma, T-Cell" 20448109 mir-17:down-regulation of the miR-17-92 cluster in malignancy tissue_expression_down hsa-mir-18a "Lymphoma, T-Cell" 20448109 mir-18a:down-regulation of the miR-17-92 cluster in malignancy tissue_expression_down hsa-mir-19a "Lymphoma, T-Cell" 20448109 mir-19a:down-regulation of the miR-17-92 cluster in malignancy tissue_expression_down hsa-mir-19b-1 "Lymphoma, T-Cell" 20448109 mir-19b:down-regulation of the miR-17-92 cluster in malignancy tissue_expression_down hsa-mir-19b-2 "Lymphoma, T-Cell" 20448109 mir-19b:down-regulation of the miR-17-92 cluster in malignancy tissue_expression_down hsa-mir-20a "Lymphoma, T-Cell" 20448109 mir-20a:down-regulation of the miR-17-92 cluster in malignancy tissue_expression_down hsa-mir-92a-1 "Lymphoma, T-Cell" 20448109 mir-92a:down-regulation of the miR-17-92 cluster in malignancy tissue_expression_down hsa-mir-92a-2 "Lymphoma, T-Cell" 20448109 mir-92a:down-regulation of the miR-17-92 cluster in malignancy tissue_expression_down hsa-mir-132 Osteoarthritis 20470394 "In RA and OA, synovial fluid concentrations of miR-16, miR-132, miR-146a, and miR-223 were significantly lower than their plasma concentrations, and there were no correlation between plasma and synovial fluid miRNAs." tissue_expression_down hsa-mir-146a Osteoarthritis 20470394 "In RA and OA, synovial fluid concentrations of miR-16, miR-132, miR-146a, and miR-223 were significantly lower than their plasma concentrations, and there were no correlation between plasma and synovial fluid miRNAs." tissue_expression_down hsa-mir-16 Osteoarthritis 20470394 "In RA and OA, synovial fluid concentrations of miR-16, miR-132, miR-146a, and miR-223 were significantly lower than their plasma concentrations, and there were no correlation between plasma and synovial fluid miRNAs." tissue_expression_down hsa-mir-223 Osteoarthritis 20470394 "In RA and OA, synovial fluid concentrations of miR-16, miR-132, miR-146a, and miR-223 were significantly lower than their plasma concentrations, and there were no correlation between plasma and synovial fluid miRNAs." tissue_expression_down hsa-mir-200a Neoplasms [unspecific] 20484038 miR-200a:Downregulation of microRNA-200 in EBV-associated gastric carcinoma tissue_expression_down hsa-mir-200b Neoplasms [unspecific] 20484038 miR-200b:Downregulation of microRNA-200 in EBV-associated gastric carcinoma tissue_expression_down hsa-mir-200c Neoplasms [unspecific] 20484038 miR-200c:Downregulation of microRNA-200 in EBV-associated gastric carcinoma tissue_expression_down hsa-mir-107 Heart Failure 20484156 miR-107: downregulated tissue_expression_down hsa-mir-139 Heart Failure 20484156 miR-139: downregulated tissue_expression_down hsa-mir-142 Heart Failure 20484156 miR-142-5p: downregulated tissue_expression_down hsa-mir-100 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-101 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-125b Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-126 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-130a Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-143 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-145 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-181a Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-26a Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-26b Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-29a Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-29c Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-30a Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-30b Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-30d Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-30e Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-320 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-451 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-652 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-886 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-99a Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_down hsa-mir-218 Gastrointestinal Neoplasms 20510072 miR-218 expression is reduced in gastric cancer. miR-218 may function as a tumor suppressor in gastric carcinoma. tissue_expression_down hsa-mir-125a "Carcinoma, Lung, Non-Small-Cell" 20569443 miR-125a-3p:Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer tissue_expression_down hsa-mir-34a Melanoma 20606648 miR-34a delivered by the GC4-targeted nanoparticles significantly downregulated the survivin expression in the metastatic tumor and reduced tumor load in the lung. tissue_expression_down hsa-mir-106b "Carcinoma, Renal Cell" 20609231 miRNA-106b:Expression of miRNA-106b in conventional renal cell carcinoma is a potential marker for prediction of early metastasis after nephrectomy tissue_expression_down hsa-mir-101-1 "Squamous Cell Carcinoma, Lung" 20620595 "miR-101:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC" tissue_expression_down hsa-mir-101-2 "Squamous Cell Carcinoma, Lung" 20620595 "miR-101:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC" tissue_expression_down hsa-mir-126 "Squamous Cell Carcinoma, Lung" 20620595 "miR-126:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC" tissue_expression_down hsa-mir-15a "Squamous Cell Carcinoma, Lung" 20620595 "miR-15a:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC" tissue_expression_down hsa-mir-193a "Squamous Cell Carcinoma, Lung" 20620595 "miR-193a-3p:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC" tissue_expression_down hsa-mir-30a "Squamous Cell Carcinoma, Lung" 20620595 "miR-30a:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC" tissue_expression_down hsa-mir-30d "Squamous Cell Carcinoma, Lung" 20620595 "miR-30d:Seven human miRNAs (miR-126, miR-193a-3p, miR-30d, miR-30a, miR-101, let-7i, and miR-15a) were found to be significantly downregulated in lung SCC" tissue_expression_down hsa-mir-520h Pancreatic Neoplasms 20628378 "miR-520h:miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion, and side populations" tissue_expression_down hsa-let-7e Adenovirus Infection 20634878 let-7e:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-101-1 Adenovirus Infection 20634878 miR-101-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-101-2 Adenovirus Infection 20634878 miR-101-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-1180 Adenovirus Infection 20634878 hsa-mir-1180:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-1184-1 Adenovirus Infection 20634878 miR-1184:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-125b-1 Adenovirus Infection 20634878 miR-125b-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-125b-2 Adenovirus Infection 20634878 miR-125b-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-148a Adenovirus Infection 20634878 miR-148a:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-148b Adenovirus Infection 20634878 miR-148b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-181b-1 Adenovirus Infection 20634878 miR-181b-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-181b-2 Adenovirus Infection 20634878 miR-181b-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-18b Adenovirus Infection 20634878 miR-18b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-196b Adenovirus Infection 20634878 miR-196b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-19b-1 Adenovirus Infection 20634878 miR-19b-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-19b-2 Adenovirus Infection 20634878 miR-19b-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-210 Adenovirus Infection 20634878 miR-210:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-219-1 Adenovirus Infection 20634878 miR-219-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-25 Adenovirus Infection 20634878 miR-25:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-26b Adenovirus Infection 20634878 miR-26b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-27a Adenovirus Infection 20634878 miR-27a:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-27b Adenovirus Infection 20634878 miR-27b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-30a Adenovirus Infection 20634878 miR-30a:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-30b Adenovirus Infection 20634878 miR-30b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-30c-1 Adenovirus Infection 20634878 miR-30c-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-30c-2 Adenovirus Infection 20634878 miR-30c-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-338 Adenovirus Infection 20634878 miR-338:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-33a Adenovirus Infection 20634878 miR-33a:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-34a Adenovirus Infection 20634878 miR-34a:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-362 Adenovirus Infection 20634878 miR-362:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-374b Adenovirus Infection 20634878 miR-374b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-421 Adenovirus Infection 20634878 miR-421:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-433 Adenovirus Infection 20634878 miR-433:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-452 Adenovirus Infection 20634878 miR-452:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-519a-1 Adenovirus Infection 20634878 miR-519a-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-582 Adenovirus Infection 20634878 miR-582:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-619 Adenovirus Infection 20634878 miR-619:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-650 Adenovirus Infection 20634878 miR-650:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-655 Adenovirus Infection 20634878 miR-655:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-92a-2 Adenovirus Infection 20634878 miR-92a-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_down hsa-mir-451 Glioblastoma 20647762 We initially identified miR-451 due to its downregulation in a glioma cell migration assay. tissue_expression_down hsa-mir-142 Squamous Cell Carcinoma 20652977 "The miRNAs miR-363, miR-33, and miR-497 were upregulated, whereas miR-155, miR-181a, miR-181b, miR-29a, miR-218, miR-222, miR-221, and miR-142-5p were downregulated in HPV-positive cells compared to both HPV-negative SCCHN and normal oral keratinocytes." tissue_expression_down hsa-mir-155 Squamous Cell Carcinoma 20652977 "The miRNAs miR-363, miR-33, and miR-497 were upregulated, whereas miR-155, miR-181a, miR-181b, miR-29a, miR-218, miR-222, miR-221, and miR-142-5p were downregulated in HPV-positive cells compared to both HPV-negative SCCHN and normal oral keratinocytes." tissue_expression_down hsa-mir-181a Squamous Cell Carcinoma 20652977 "The miRNAs miR-363, miR-33, and miR-497 were upregulated, whereas miR-155, miR-181a, miR-181b, miR-29a, miR-218, miR-222, miR-221, and miR-142-5p were downregulated in HPV-positive cells compared to both HPV-negative SCCHN and normal oral keratinocytes." tissue_expression_down hsa-mir-181b Squamous Cell Carcinoma 20652977 "The miRNAs miR-363, miR-33, and miR-497 were upregulated, whereas miR-155, miR-181a, miR-181b, miR-29a, miR-218, miR-222, miR-221, and miR-142-5p were downregulated in HPV-positive cells compared to both HPV-negative SCCHN and normal oral keratinocytes." tissue_expression_down hsa-mir-218 Squamous Cell Carcinoma 20652977 "The miRNAs miR-363, miR-33, and miR-497 were upregulated, whereas miR-155, miR-181a, miR-181b, miR-29a, miR-218, miR-222, miR-221, and miR-142-5p were downregulated in HPV-positive cells compared to both HPV-negative SCCHN and normal oral keratinocytes." tissue_expression_down hsa-mir-221 Squamous Cell Carcinoma 20652977 "The miRNAs miR-363, miR-33, and miR-497 were upregulated, whereas miR-155, miR-181a, miR-181b, miR-29a, miR-218, miR-222, miR-221, and miR-142-5p were downregulated in HPV-positive cells compared to both HPV-negative SCCHN and normal oral keratinocytes." tissue_expression_down hsa-mir-222 Squamous Cell Carcinoma 20652977 "The miRNAs miR-363, miR-33, and miR-497 were upregulated, whereas miR-155, miR-181a, miR-181b, miR-29a, miR-218, miR-222, miR-221, and miR-142-5p were downregulated in HPV-positive cells compared to both HPV-negative SCCHN and normal oral keratinocytes." tissue_expression_down hsa-mir-29a Squamous Cell Carcinoma 20652977 "The miRNAs miR-363, miR-33, and miR-497 were upregulated, whereas miR-155, miR-181a, miR-181b, miR-29a, miR-218, miR-222, miR-221, and miR-142-5p were downregulated in HPV-positive cells compared to both HPV-negative SCCHN and normal oral keratinocytes." tissue_expression_down hsa-mir-218 Astrocytoma 20711171 Inhibition of two glioblastoma-upregulated miRNAs (miR-21 and miR-23a) and exogenous overexpression of two glioblastoma-downregulated miRNAs (miR-218 and miR-219-5p) resulted in reduced soft agar colony formation but showed varying effects on cell proliferation and chemosensitivity. tissue_expression_down hsa-mir-219 Astrocytoma 20711171 Inhibition of two glioblastoma-upregulated miRNAs (miR-21 and miR-23a) and exogenous overexpression of two glioblastoma-downregulated miRNAs (miR-218 and miR-219-5p) resulted in reduced soft agar colony formation but showed varying effects on cell proliferation and chemosensitivity. tissue_expression_down hsa-mir-17 Multiple Sclerosis 20711463 "In all MS subtypes miR-17 and miR-20a were significantly under-expressed in MS, confirmed by RT-PCR. " tissue_expression_down hsa-mir-20a Multiple Sclerosis 20711463 "In all MS subtypes miR-17 and miR-20a were significantly under-expressed in MS, confirmed by RT-PCR. " tissue_expression_down hsa-mir-145 Ovarian Neoplasms 20716115 "Reduced miR-145 and miR-214 and elevated let-7f, miR-182, miR-210, miR-200c, miR-222 and miR-23a levels were found in effusions in both sets." tissue_expression_down hsa-mir-214 Ovarian Neoplasms 20716115 "Reduced miR-145 and miR-214 and elevated let-7f, miR-182, miR-210, miR-200c, miR-222 and miR-23a levels were found in effusions in both sets." tissue_expression_down hsa-mir-126 Breast Neoplasms 20801493 "A high correlation of miRNA expression level was found between breast tumor tissues and sera. MiR-21, miR-106a and miR-155 were significantly over-expressed in the tumor specimens compared with those in normal controls (P < 0.05), whereas miR-126, miR-199a and miR-335 were significantly under-expressed (P < 0.05)." tissue_expression_down hsa-mir-199a Breast Neoplasms 20801493 "A high correlation of miRNA expression level was found between breast tumor tissues and sera. MiR-21, miR-106a and miR-155 were significantly over-expressed in the tumor specimens compared with those in normal controls (P < 0.05), whereas miR-126, miR-199a and miR-335 were significantly under-expressed (P < 0.05)." tissue_expression_down hsa-mir-335 Breast Neoplasms 20801493 "A high correlation of miRNA expression level was found between breast tumor tissues and sera. MiR-21, miR-106a and miR-155 were significantly over-expressed in the tumor specimens compared with those in normal controls (P < 0.05), whereas miR-126, miR-199a and miR-335 were significantly under-expressed (P < 0.05)." tissue_expression_down hsa-mir-1-1 Laryngeal Neoplasms 20806854 downregulated by 5 multiple tissue_expression_down hsa-mir-1-2 Laryngeal Neoplasms 20806854 downregulated by 5 multiple tissue_expression_down hsa-mir-133a-1 Laryngeal Neoplasms 20806854 downregulated by 5 multiple tissue_expression_down hsa-mir-133a-2 Laryngeal Neoplasms 20806854 downregulated by 5 multiple tissue_expression_down hsa-mir-144 Laryngeal Neoplasms 20806854 downregulated by 5 multiple tissue_expression_down hsa-mir-206 Laryngeal Neoplasms 20806854 downregulated by 5 multiple tissue_expression_down hsa-mir-375 Laryngeal Neoplasms 20806854 downregulated by 5 multiple tissue_expression_down hsa-mir-378a Laryngeal Neoplasms 20806854 downregulated by 5 multiple tissue_expression_down hsa-mir-384 Laryngeal Neoplasms 20806854 downregulated by 5 multiple tissue_expression_down hsa-mir-422a Laryngeal Neoplasms 20806854 downregulated by 5 multiple tissue_expression_down hsa-mir-486 Laryngeal Neoplasms 20806854 miR-486-5p: downregulated by 5 multiple tissue_expression_down hsa-mir-487a Laryngeal Neoplasms 20806854 downregulated by 5 multiple tissue_expression_down hsa-mir-21 Spinal Cord Injuries 20816819 "spinal cord injury (SCI)results in increased expression of miR Let-7a and miR16 while exercise leads to elevated levels of miR21 and decreased levels of miR15b. These changes in miR expression are correlated with changes in expression of their target genes: pro-apoptotic (decreased PTEN, PDCD4, and RAS mRNA) and anti-apoptotic (increased Bcl-2 mRNA) target genes. This is accompanied by a down-regulation of mRNA for caspase-7 and caspase-9 and reduced levels of caspase-7 protein." tissue_expression_down hsa-mir-125b Melanoma 20827223 Downregulation of miR-125b in metastatic cutaneous malignant melanoma. tissue_expression_down hsa-mir-195 Aortic Insufficiency 20845893 "miR-195:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI." tissue_expression_down hsa-mir-195 Aortic Stenosis 20845893 "miR-195:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI." tissue_expression_down hsa-mir-195 Chronic Heart Failure 20845893 "miR-195:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI." tissue_expression_down hsa-mir-26a-1 Aortic Insufficiency 20845893 "MiR-26a:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI." tissue_expression_down hsa-mir-26a-1 Aortic Stenosis 20845893 "MiR-26a:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI." tissue_expression_down hsa-mir-26a-1 Chronic Heart Failure 20845893 "MiR-26a:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI." tissue_expression_down hsa-mir-26a-2 Aortic Insufficiency 20845893 "MiR-26a:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI." tissue_expression_down hsa-mir-26a-2 Aortic Stenosis 20845893 "MiR-26a:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI." tissue_expression_down hsa-mir-26a-2 Chronic Heart Failure 20845893 "MiR-26a:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI." tissue_expression_down hsa-mir-30b Aortic Insufficiency 20845893 "MiR-30b:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI." tissue_expression_down hsa-mir-30b Aortic Stenosis 20845893 "MiR-30b:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI." tissue_expression_down hsa-mir-30b Chronic Heart Failure 20845893 "MiR-30b:MiR-26a, miR-30b, and miR-195 were each decreased in the aortic valves of patients requiring AVR due to AS, compared to those requiring replacement due to AI." tissue_expression_down hsa-mir-21 Neuroma 20856158 miR-21:Elevated levels of hsa-microRNA-21 (miR-21) in vestibular schwannomas (VSs) may contribute to tumor growth by downregulating the tumor suppressor phosphatase and tensin homolog (PTEN) and consequent hyperactivation of protein kinase B tissue_expression_down hsa-mir-126 Colon Neoplasms 20859756 "miR-126:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-142 Colon Neoplasms 20859756 "miR-142-3p:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-146a Colon Neoplasms 20859756 "miR-146a:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-152 Colon Neoplasms 20859756 "miR-152:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-155 Colon Neoplasms 20859756 "miR-155:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-205 Colon Neoplasms 20859756 "miR-205:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-365a Colon Neoplasms 20859756 "miR-365:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-365b Colon Neoplasms 20859756 "miR-365:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-449a Colon Neoplasms 20859756 "miR-449:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-518c Colon Neoplasms 20859756 "miR-518c:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-552 Colon Neoplasms 20859756 "miR-552:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-584 Colon Neoplasms 20859756 "miR-584:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-615 Colon Neoplasms 20859756 "miR-615:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-622 Colon Neoplasms 20859756 "miR-622:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-630 Colon Neoplasms 20859756 "miR-630:In particular, miR-126, miR-142-3p, miR-155, miR-552, and miR-630 were all upregulated, whereas miR-146a, miR-152, miR-205, miR-365, miR-449, miR-518c, miR-584, miR-615, and miR-622 were downregulated after NGX6 transfection." tissue_expression_down hsa-mir-122 "Carcinoma, Hepatocellular" 20859956 miR-122a:microRNA-122a (miR-122a) is a liver-specific miRNA that is frequently downregulated in hepatocellular carcinoma (HCC) tissue_expression_down hsa-mir-106b Prostate Neoplasms 20878953 Down-regulation of microRNA 106b is involved in p21-mediated cell cycle arrest in response to radiation in prostate cancer cells. tissue_expression_down hsa-mir-135a "Carcinoma, Rectal" 20955366 The miR-135a&b were the miRNAs most down-regulated by CM-1. tissue_expression_down hsa-mir-135b "Carcinoma, Rectal" 20955366 The miR-135a&b were the miRNAs most down-regulated by CM-1. tissue_expression_down hsa-mir-122 "Fatty Liver, Non-Alcoholic" 20956972 "The miRNAs analysis showed the significant downregulation of three miRNAs (miR-122, miR-451 and miR-27) and the upregulation of miR-200a, miR-200b and miR-429 in HFD, SD-HF and HFD-HF rats" tissue_expression_down hsa-mir-21 "Fatty Liver, Non-Alcoholic" 20956972 "Besides, miR-21 expression was significantly decreased only in fructose-enriched diets." tissue_expression_down hsa-mir-27 "Fatty Liver, Non-Alcoholic" 20956972 "The miRNAs analysis showed the significant downregulation of three miRNAs (miR-122, miR-451 and miR-27) and the upregulation of miR-200a, miR-200b and miR-429 in HFD, SD-HF and HFD-HF rats" tissue_expression_down hsa-mir-451 "Fatty Liver, Non-Alcoholic" 20956972 "The miRNAs analysis showed the significant downregulation of three miRNAs (miR-122, miR-451 and miR-27) and the upregulation of miR-200a, miR-200b and miR-429 in HFD, SD-HF and HFD-HF rats" tissue_expression_down hsa-mir-15a Lymphoma 21118128 "Both decreased expression of miR-15a and miR-16-1 and increased nucleolin have been shown to be associated with increased Bcl2 expression and resistance to apoptosis in the common human disease, chronic lymphocytic leukaemia." tissue_expression_down hsa-mir-16-1 Lymphoma 21118128 "Both decreased expression of miR-15a and miR-16-1 and increased nucleolin have been shown to be associated with increased Bcl2 expression and resistance to apoptosis in the common human disease, chronic lymphocytic leukaemia." tissue_expression_down hsa-mir-221 Gastrointestinal Neoplasms 21132270 Down-regulation of miR-221 and miR-222 correlates with pronounced Kit expression in gastrointestinal stromal tumors tissue_expression_down hsa-mir-222 Gastrointestinal Neoplasms 21132270 Down-regulation of miR-221 and miR-222 correlates with pronounced Kit expression in gastrointestinal stromal tumors tissue_expression_down hsa-mir-145 Hepatoblastoma 21145831 downregulated in early stages of HBV-associated multistep hepatocarcinogenesis. tissue_expression_down hsa-mir-199b Hepatoblastoma 21145831 downregulated in early stages of HBV-associated multistep hepatocarcinogenesis. tissue_expression_down hsa-mir-29b-1 Myotonic Muscular Dystrophy 21169019 "We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls." tissue_expression_down hsa-mir-29b-2 Myotonic Muscular Dystrophy 21169019 "We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls." tissue_expression_down hsa-mir-29c Myotonic Muscular Dystrophy 21169019 "We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls." tissue_expression_down hsa-mir-33a Myotonic Muscular Dystrophy 21169019 "We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls." tissue_expression_down hsa-mir-33b Myotonic Muscular Dystrophy 21169019 "We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls." tissue_expression_down hsa-mir-342 Breast Neoplasms 21172025 Downregulation of miR-342 is Associated with Tamoxifen Resistant Breast Tumors. tissue_expression_down hsa-mir-148b Liver Neoplasms 21176238 mir-148b* is underexpressed in side population of HCC cells compared to fetal liver cells tissue_expression_down hsa-mir-200a Liver Neoplasms 21176238 mir-200a* is underexpressed in side population of HCC cells compared to fetal liver cells tissue_expression_down hsa-mir-21 Prostate Neoplasms 21177307 "We also observed a significant down-regulation of androgen-regulated miRNA-21 and up-regulation of a tumor suppressor, miRNA-330, in tumors of mice treated with EGCG" tissue_expression_down hsa-mir-124-2 Glioblastoma 21196113 miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion. tissue_expression_down hsa-mir-148b Gastric Neoplasms 21205300 MicroRNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferation. tissue_expression_down hsa-mir-143 Glioblastoma 21211035 "down regulation of miR-143, -145, -253-5p and miR-452 by SOX2" tissue_expression_down hsa-mir-145 Glioblastoma 21211035 "down regulation of miR-143, -145, -253-5p and miR-452 by SOX2" tissue_expression_down hsa-mir-452 Glioblastoma 21211035 "down regulation of miR-143, -145, -253-5p and miR-452 by SOX2" tissue_expression_down hsa-mir-146a Myelodysplastic Syndromes 21211043 miR-378 and miR-146a showed reduced gene expression in the patients. tissue_expression_down hsa-mir-378a Myelodysplastic Syndromes 21211043 miR-378 and miR-146a showed reduced gene expression in the patients. tissue_expression_down hsa-mir-143 Esophageal Neoplasms 21218087 MiRNA profile in esophageal squamous cell carcinoma: Downregulation of miR-143 and miR-145. tissue_expression_down hsa-mir-145 Esophageal Neoplasms 21218087 MiRNA profile in esophageal squamous cell carcinoma: Downregulation of miR-143 and miR-145. tissue_expression_down hsa-mir-300 Urinary Bladder Cancer 21223810 "In grade I, grade II, grade III, grade I + II + III, infiltrating and non-infiltrating groups, hsa-miR-29b-1* was up-regulated while hsa-miR-923 and hsa-miR-300 were down-regulated" tissue_expression_down hsa-mir-135b "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_down hsa-mir-197 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_down hsa-mir-224 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_down hsa-mir-34a "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_down hsa-mir-378a "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_down hsa-mir-520h "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_down hsa-mir-518b Esophageal Neoplasms 21269950 hsa-mir-126 is upregulated and hsa-miR-518b is downregulated in esophageal squamous carcinoma tissue_expression_down hsa-mir-181a-1 "Squamous Cell Carcinoma, Head and Neck" 21274007 "deltaNp63alpha-dependent miRNA miR-181a, miR-519a, and miR-374a downregulation in HNSCC,miR-630 upregulation in HNSCC" tissue_expression_down hsa-mir-181a-2 "Squamous Cell Carcinoma, Head and Neck" 21274007 "deltaNp63alpha-dependent miRNA miR-181a, miR-519a, and miR-374a downregulation in HNSCC,miR-630 upregulation in HNSCC" tissue_expression_down hsa-mir-519a-1 "Squamous Cell Carcinoma, Head and Neck" 21274007 "deltaNp63alpha-dependent miRNA miR-181a, miR-519a, and miR-374a downregulation in HNSCC,miR-630 upregulation in HNSCC" tissue_expression_down hsa-mir-519a-2 "Squamous Cell Carcinoma, Head and Neck" 21274007 "deltaNp63alpha-dependent miRNA miR-181a, miR-519a, and miR-374a downregulation in HNSCC,miR-630 upregulation in HNSCC" tissue_expression_down hsa-mir-141 Learned Helplessness 21275079 "mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain." tissue_expression_down hsa-mir-182 Learned Helplessness 21275079 "mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain." tissue_expression_down hsa-mir-183 Learned Helplessness 21275079 "mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain." tissue_expression_down hsa-mir-200a Learned Helplessness 21275079 "mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain." tissue_expression_down hsa-mir-200b Learned Helplessness 21275079 "mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain." tissue_expression_down hsa-mir-200c Learned Helplessness 21275079 "mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain." tissue_expression_down hsa-mir-429 Learned Helplessness 21275079 "mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain." tissue_expression_down hsa-mir-96 Learned Helplessness 21275079 "mir-96, 141, 182, 183, 183*, 298, 200a, 200a*, 200b, 200b*, 200c, 429 are significantly downregulated in non-learned helplessness relative to tested controls in rat brain." tissue_expression_down hsa-let-7g Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-126 Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-196a-1 Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-196a-2 Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-200a Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-200b Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-200c Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-31 Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-338 Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-7-1 Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-7-2 Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-7-3 Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-98 Gastrointestinal Neoplasms 21293479 "In the HCPT-resistant gastric cancer cells, the levels of 25 miRNAs were deregulated, including miR-196a, miR-200 family, miR-338, miR-126, miR-31, miR-98, let-7g, and miR-7." tissue_expression_down hsa-mir-218-1 "Carcinoma, Cervical" 21309487 infection with high-risk HPV lowered the expression of miR-218 and that down-regulation of miR-218 was involved in the pathogenesis of cervical cancer tissue_expression_down hsa-mir-218-2 "Carcinoma, Cervical" 21309487 infection with high-risk HPV lowered the expression of miR-218 and that down-regulation of miR-218 was involved in the pathogenesis of cervical cancer tissue_expression_down hsa-mir-30c-1 Mesothelioma 21317924 Hsa-miR-17* was significantly upregulated and hsa-miR-30c was significantly downregulated by Onconase treatment in all cell lines tissue_expression_down hsa-mir-30c-2 Mesothelioma 21317924 Hsa-miR-17* was significantly upregulated and hsa-miR-30c was significantly downregulated by Onconase treatment in all cell lines tissue_expression_down hsa-mir-34c Ovarian Neoplasms 21321636 "miR-449b and miR-34c on inducing down-regulation of cell cycle-related proteins and cycle arrests in SKOV3-ipl cell, an ovarian cancer cell line." tissue_expression_down hsa-mir-499a Ovarian Neoplasms 21321636 "miR-449b and miR-34c on inducing down-regulation of cell cycle-related proteins and cycle arrests in SKOV3-ipl cell, an ovarian cancer cell line." tissue_expression_down hsa-mir-34b Lung Neoplasms 21339737 "A microRNA, miR-34b, that suppresses the expression of alpha4 through specific binding to the 3'-untranslated region of alpha4 is downregulated in transformed or human lung tumors." tissue_expression_down hsa-mir-200c Ovarian Neoplasms 21345725 "miR-200c has potential as a predictor of survival, and is a biomarker of relapse, in stage I EOC." tissue_expression_down hsa-mir-146a Gastrointestinal Neoplasms 21347720 MicroRNA-146a is down-regulated in gastric cancer and regulates cell proliferation and apoptosis. tissue_expression_down hsa-mir-34c Prostate Neoplasms 21351256 miR-34c is downregulated in prostate cancer and exerts tumor suppressive functions. tissue_expression_down hsa-mir-21 Psoriasis 21373745 "Real-time PCR and immunohistochemistry showed that p63 expression was not significantly affected, whereas NB-UVB phototherapy significantly decreased expression ofmiR-21 (p = 0.003) and increased miR-125b levels (p = 0.003). The results indicate that the unresolved p63 abnormality in treated epidermis may play a role in maintenance of this disease." tissue_expression_down hsa-let-7a-1 Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-let-7a-2 Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-let-7a-3 Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-let-7b Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-let-7c Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-let-7d Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-let-7e Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-let-7f-1 Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-let-7f-2 Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-let-7g Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-let-7i Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-mir-34b Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-mir-34c Nasopharyngeal Neoplasms 21373758 underexpressed tissue_expression_down hsa-mir-221 Prostate Neoplasms 21378318 miR-221 Is Down-regulated in TMPRSS2:ERG Fusion-positive Prostate Cancer. tissue_expression_down hsa-mir-222 Prostate Neoplasms 21378318 miR-221 Is Down-regulated in TMPRSS2:ERG Fusion-positive Prostate Cancer. tissue_expression_down hsa-mir-99a Neoplasms [unspecific] 21383697 miR-99a-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways. tissue_expression_down hsa-mir-181a-1 Systemic Lupus Erythematosus 21385555 miR-181-a was significantly downregulated in SLE pediatrics as compared to healthy controls. tissue_expression_down hsa-mir-181a-2 Systemic Lupus Erythematosus 21385555 miR-181-a was significantly downregulated in SLE pediatrics as compared to healthy controls. tissue_expression_down hsa-mir-195 Colorectal Carcinoma 21390519 Downregulation of miR-195 correlates with lymph node metastasis and poor prognosis in colorectal cancer. tissue_expression_down hsa-mir-1-1 Hypertrophy 21418519 IGF-1 deficiency retards AAC-induced cardiac hypertrophic and contractile changes via alleviating downregulation of miR-1 and miR-133a in response to left ventricular pressure overload. tissue_expression_down hsa-mir-1-2 Hypertrophy 21418519 IGF-1 deficiency retards AAC-induced cardiac hypertrophic and contractile changes via alleviating downregulation of miR-1 and miR-133a in response to left ventricular pressure overload. tissue_expression_down hsa-mir-133a-1 Hypertrophy 21418519 IGF-1 deficiency retards AAC-induced cardiac hypertrophic and contractile changes via alleviating downregulation of miR-1 and miR-133a in response to left ventricular pressure overload. tissue_expression_down hsa-mir-133a-2 Hypertrophy 21418519 IGF-1 deficiency retards AAC-induced cardiac hypertrophic and contractile changes via alleviating downregulation of miR-1 and miR-133a in response to left ventricular pressure overload. tissue_expression_down hsa-mir-449a Gastric Neoplasms 21418558 miR-449 inhibits cell proliferation and is down-regulated in gastric cancer. tissue_expression_down hsa-mir-449b Gastric Neoplasms 21418558 miR-449 inhibits cell proliferation and is down-regulated in gastric cancer. tissue_expression_down hsa-mir-449c Gastric Neoplasms 21418558 miR-449 inhibits cell proliferation and is down-regulated in gastric cancer. tissue_expression_down hsa-mir-10a Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. tissue_expression_down hsa-mir-141 Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. tissue_expression_down hsa-mir-200a Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. tissue_expression_down hsa-mir-200b Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. tissue_expression_down hsa-mir-200c Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. tissue_expression_down hsa-mir-203 Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. tissue_expression_down hsa-mir-34c Endometriosis 21436257 miR-34c-5p down-regulated in endometriomas compared with endometrium. tissue_expression_down hsa-mir-375 Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. tissue_expression_down hsa-mir-429 Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. tissue_expression_down hsa-mir-449b Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. tissue_expression_down hsa-mir-504 Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. tissue_expression_down hsa-mir-873 Endometriosis 21436257 down-regulated in endometriomas compared with endometrium. tissue_expression_down hsa-mir-141 Barrett Esophagus 21448356 miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus. tissue_expression_down hsa-mir-200a Barrett Esophagus 21448356 miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus. tissue_expression_down hsa-mir-200b Barrett Esophagus 21448356 miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus. tissue_expression_down hsa-mir-200c Barrett Esophagus 21448356 miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus. tissue_expression_down hsa-mir-429 Barrett Esophagus 21448356 miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus. tissue_expression_down hsa-mir-125b-1 Melanoma 21460750 the expression of miRNA-125b (miR-125b) was two-fold lower in malignant melanoma producing lymph node micrometastases than in nonmetastasizing tumors. MicroRNA miR-125b induces senescence in human melanoma cells.We propose that downregulation of miR-125b in an early cutaneous malignant melanoma can contribute to the increased metastatic capability of this tumor. tissue_expression_down hsa-mir-125b-2 Melanoma 21460750 the expression of miRNA-125b (miR-125b) was two-fold lower in malignant melanoma producing lymph node micrometastases than in nonmetastasizing tumors. MicroRNA miR-125b induces senescence in human melanoma cells.We propose that downregulation of miR-125b in an early cutaneous malignant melanoma can contribute to the increased metastatic capability of this tumor. tissue_expression_down hsa-let-7a-1 Pancreatic Neoplasms 21463919 "over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype" tissue_expression_down hsa-let-7a-2 Pancreatic Neoplasms 21463919 "over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype" tissue_expression_down hsa-let-7a-3 Pancreatic Neoplasms 21463919 "over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype" tissue_expression_down hsa-let-7b Pancreatic Neoplasms 21463919 "over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype" tissue_expression_down hsa-let-7c Pancreatic Neoplasms 21463919 "over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype" tissue_expression_down hsa-mir-200b Pancreatic Neoplasms 21463919 "over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype" tissue_expression_down hsa-mir-200c Pancreatic Neoplasms 21463919 "over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype" tissue_expression_down hsa-mir-143 Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, downregulated." tissue_expression_down hsa-mir-145 Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, downregulated." tissue_expression_down hsa-let-7a-1 "Carcinoma, Lung, Non-Small-Cell" 21468581 "Let-7a miRNAs were under-expressed in the blood of NSCLC patients, as well as NSCLC cells and NSCLC tissues, compared to normal controls." tissue_expression_down hsa-let-7a-2 "Carcinoma, Lung, Non-Small-Cell" 21468581 "Let-7a miRNAs were under-expressed in the blood of NSCLC patients, as well as NSCLC cells and NSCLC tissues, compared to normal controls." tissue_expression_down hsa-let-7a-3 "Carcinoma, Lung, Non-Small-Cell" 21468581 "Let-7a miRNAs were under-expressed in the blood of NSCLC patients, as well as NSCLC cells and NSCLC tissues, compared to normal controls." tissue_expression_down hsa-mir-125b-1 "Carcinoma, Adrenocortical" 21472710 "miRs -100, -125b, and -195 were significantly down-regulated, whereas miR-483-5p was significantly up-regulated in malignant as compared with benign tumors." tissue_expression_down hsa-mir-125b-2 "Carcinoma, Adrenocortical" 21472710 "miRs -100, -125b, and -195 were significantly down-regulated, whereas miR-483-5p was significantly up-regulated in malignant as compared with benign tumors." tissue_expression_down hsa-mir-195 "Carcinoma, Adrenocortical" 21472710 "miRs -100, -125b, and -195 were significantly down-regulated, whereas miR-483-5p was significantly up-regulated in malignant as compared with benign tumors." tissue_expression_down hsa-mir-20a Glioblastoma 21483847 "miR-20a upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma." tissue_expression_down hsa-mir-221 Glioblastoma 21483847 "miR-221 downregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma." tissue_expression_down hsa-mir-222 Glioblastoma 21483847 "miR-222 downregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma." tissue_expression_down hsa-mir-31 Glioblastoma 21483847 "miR-31 downregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma." tissue_expression_down hsa-mir-145 Melanoma 21509659 significantly down-regulated in uveal melanomas compared with normal uveal tissues tissue_expression_down hsa-mir-204 Melanoma 21509659 significantly down-regulated in uveal melanomas compared with normal uveal tissues tissue_expression_down hsa-mir-15a Prostate Neoplasms 21532615 miR-15 and miR-16 are downregulated in fibroblasts surrounding the prostate tumors of the majority of 23 patients analyzed. tissue_expression_down hsa-mir-15b Prostate Neoplasms 21532615 miR-15 and miR-16 are downregulated in fibroblasts surrounding the prostate tumors of the majority of 23 patients analyzed. tissue_expression_down hsa-mir-16-1 Prostate Neoplasms 21532615 miR-15 and miR-16 are downregulated in fibroblasts surrounding the prostate tumors of the majority of 23 patients analyzed. tissue_expression_down hsa-mir-16-2 Prostate Neoplasms 21532615 miR-15 and miR-16 are downregulated in fibroblasts surrounding the prostate tumors of the majority of 23 patients analyzed. tissue_expression_down hsa-mir-1-1 Thyroid Neoplasms 21537871 "miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC." tissue_expression_down hsa-mir-1-2 Thyroid Neoplasms 21537871 "miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC." tissue_expression_down hsa-mir-133b Thyroid Neoplasms 21537871 "miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC." tissue_expression_down hsa-mir-138-1 Thyroid Neoplasms 21537871 "miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC." tissue_expression_down hsa-mir-138-2 Thyroid Neoplasms 21537871 "miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC." tissue_expression_down hsa-mir-34b Thyroid Neoplasms 21537871 "miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC." tissue_expression_down hsa-let-7a-1 "Carcinoma, Lung, Non-Small-Cell" 21544802 "The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased." tissue_expression_down hsa-let-7a-2 "Carcinoma, Lung, Non-Small-Cell" 21544802 "The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased." tissue_expression_down hsa-let-7a-3 "Carcinoma, Lung, Non-Small-Cell" 21544802 "The expression of miR-146b, miR-221, let-7a, miR-155, miR-17-5p, miR-27a and miR-106a were significantly reduced in the serum of NSCLC cases while miR-29c was significantly increased." tissue_expression_down hsa-let-7b "Carcinoma, Lung, Non-Small-Cell" 21544802 Reduced plasma expression of let-7b was modestly associated with worse cancer-specific mortality in all patients and reduced serum expression of miR-223 was modestly associated with cancer-specific mortality in stage IA/B patients. tissue_expression_down hsa-mir-143 Colorectal Carcinoma 21551242 "MiR-20a and miR-31 were found to be significantly upregulated in more than one study, and miR-143 and miR-145 were found to be significantly downregulated in CRC tissue in six or more studies." tissue_expression_down hsa-mir-145 Colorectal Carcinoma 21551242 "MiR-20a and miR-31 were found to be significantly upregulated in more than one study, and miR-143 and miR-145 were found to be significantly downregulated in CRC tissue in six or more studies." tissue_expression_down hsa-mir-143 "Colitis, Ulcerative" 21557394 miR-143 and miR-145 are downregulated in ulcerative colitis tissue_expression_down hsa-mir-145 "Colitis, Ulcerative" 21557394 miR-143 and miR-145 are downregulated in ulcerative colitis tissue_expression_down hsa-mir-199b "Carcinoma, Hepatocellular" 21557766 "hsa-mir-199b-5p: Patients with lower levels of miR-199b expression had poorer overall survival and progression-free survival rates, whereas patients with higher levels of miR-199b expression had better survival." tissue_expression_down hsa-mir-34b Parkinson Disease 21558425 "This miRNA was downregulated in brain areas with variable neuropathological affectation at clinical (motor) stages (Braak stages 4 and 5) of the disease,including the amygdala, frontal cortex, substantia nigra and cerebellum. This miRNA modulate mitochondrial function." tissue_expression_down hsa-mir-34c Parkinson Disease 21558425 "This miRNA was downregulated in brain areas with variable neuropathological affectation at clinical (motor) stages (Braak stages 4 and 5) of the disease,including the amygdala, frontal cortex, substantia nigra and cerebellum. This miRNA modulate mitochondrial function." tissue_expression_down hsa-mir-100 Head And Neck Neoplasms 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_down hsa-mir-100 "Squamous Cell Carcinoma, Head and Neck" 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_down hsa-mir-130a Head And Neck Neoplasms 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_down hsa-mir-130a "Squamous Cell Carcinoma, Head and Neck" 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_down hsa-mir-197 Head And Neck Neoplasms 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_down hsa-mir-197 "Squamous Cell Carcinoma, Head and Neck" 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_down hsa-mir-1224 Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_down hsa-mir-202 Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_down hsa-mir-605 Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_down hsa-mir-671 Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_down hsa-mir-939 Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_down hsa-mir-133b Colorectal Carcinoma 21573504 "High expression of miR-185 and low expression of miR-133b were correlated with poor survival (p=0.001 and 0.028, respectively) and metastasis (p=0.007 and 0.036, respectively) in colorectal cancer." tissue_expression_down hsa-mir-17 Prostate Neoplasms 21592394 "Among these miR-22, miR-29ab, miR-134, miR-1207-5p and miR-371-5p are up regulated, while miR-17 and miR-20a, members of the miR-17/92 cluster are down regulated." tissue_expression_down hsa-mir-18 Prostate Neoplasms 21592394 "Among these miR-22, miR-29ab, miR-134, miR-1207-5p and miR-371-5p are up regulated, while miR-17 and miR-20a, members of the miR-17/92 cluster are down regulated." tissue_expression_down hsa-mir-19a Prostate Neoplasms 21592394 "Among these miR-22, miR-29ab, miR-134, miR-1207-5p and miR-371-5p are up regulated, while miR-17 and miR-20a, members of the miR-17/92 cluster are down regulated." tissue_expression_down hsa-mir-19b-1 Prostate Neoplasms 21592394 "Among these miR-22, miR-29ab, miR-134, miR-1207-5p and miR-371-5p are up regulated, while miR-17 and miR-20a, members of the miR-17/92 cluster are down regulated." tissue_expression_down hsa-mir-20a Prostate Neoplasms 21592394 "Among these miR-22, miR-29ab, miR-134, miR-1207-5p and miR-371-5p are up regulated, while miR-17 and miR-20a, members of the miR-17/92 cluster are down regulated." tissue_expression_down hsa-mir-92-1 Prostate Neoplasms 21592394 "Among these miR-22, miR-29ab, miR-134, miR-1207-5p and miR-371-5p are up regulated, while miR-17 and miR-20a, members of the miR-17/92 cluster are down regulated." tissue_expression_down hsa-mir-21 Prostate Neoplasms 21594291 "In addition, anti-invasive microRNAs such as miR-335, miR-205, miR-200, and miR-126, were up-regulated, whereas pro-invasive microRNA such as miR-21 and miR-373, were down-regulated." tissue_expression_down hsa-mir-373 Prostate Neoplasms 21594291 "In addition, anti-invasive microRNAs such as miR-335, miR-205, miR-200, and miR-126, were up-regulated, whereas pro-invasive microRNA such as miR-21 and miR-373, were down-regulated." tissue_expression_down hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 21622546 "Eighteen cases were classified as AD and 13 as SCC by light microscopy and immunocytochemistry. miRNA expression profiles demonstrated considerable, statistically significant differences between AD and SCC, showing an upregulation of hsa-let-7a, hsa-let-7b, hsa-let-7c,hsa-let-7f, hsa-let-7g, hsa-let-7i, and hsa-miR-98 and a downregulation of hsa-miR-205 in AD specimens" tissue_expression_down hsa-mir-15a "Carcinoma, Hepatocellular" 21629246 Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro. tissue_expression_down hsa-mir-16-1 "Carcinoma, Hepatocellular" 21629246 Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro. tissue_expression_down hsa-mir-16-2 "Carcinoma, Hepatocellular" 21629246 Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro. tissue_expression_down hsa-mir-30a "Carcinoma, Lung, Non-Small-Cell" 21633953 MicroRNA-30a inhibits epithelial-to-mesenchymal transition by targeting Snai1 and is downregulated in non-small cell lung cancer. tissue_expression_down hsa-mir-101-1 Head And Neck Neoplasms 21637912 hsa-mir-101 was downregulated compared with normal tissue. tissue_expression_down hsa-mir-101-2 Head And Neck Neoplasms 21637912 hsa-mir-101 was downregulated compared with normal tissue. tissue_expression_down hsa-mir-141 Head And Neck Neoplasms 21637912 hsa-mir-141 was downregulated compared with normal tissue. tissue_expression_down hsa-mir-95 Head And Neck Neoplasms 21637912 hsa-mir-95 was downregulated compared with normal tissue. tissue_expression_down hsa-mir-199a-1 Osteosarcoma 21666078 MicroRNA-199a-3p Is Downregulated in Human Osteosarcoma and Regulates Cell Proliferation and Migration. tissue_expression_down hsa-mir-199a-2 Osteosarcoma 21666078 MicroRNA-199a-3p Is Downregulated in Human Osteosarcoma and Regulates Cell Proliferation and Migration. tissue_expression_down hsa-mir-451a Breast Neoplasms 21666713 Tamoxifen downregulation of miR-451 increases 14-3-3 and promotes breast cancer cell survival and endocrine resistance. tissue_expression_down hsa-mir-370 Gastric Neoplasms 21666718 Overexpression of miR-370 and downregulation of its novel target TGFbeta-RII contribute to the progression of gastric carcinoma. tissue_expression_down hsa-mir-125a "Carcinoma, Rectal" 21671476 "One of the most up-regulated miRNAs, miRNA-106a, was consistently reported to be differentially expressed in six studies and the five most down-regulated miRNAs, miR-30a-3p, miR-139, miR-145, miR-125a and miR-133a, were consistently reported to be differentially expressed in four studies." tissue_expression_down hsa-mir-133a "Carcinoma, Rectal" 21671476 "One of the most up-regulated miRNAs, miRNA-106a, was consistently reported to be differentially expressed in six studies and the five most down-regulated miRNAs, miR-30a-3p, miR-139, miR-145, miR-125a and miR-133a, were consistently reported to be differentially expressed in four studies." tissue_expression_down hsa-mir-139 "Carcinoma, Rectal" 21671476 "One of the most up-regulated miRNAs, miRNA-106a, was consistently reported to be differentially expressed in six studies and the five most down-regulated miRNAs, miR-30a-3p, miR-139, miR-145, miR-125a and miR-133a, were consistently reported to be differentially expressed in four studies." tissue_expression_down hsa-mir-145 "Carcinoma, Rectal" 21671476 "One of the most up-regulated miRNAs, miRNA-106a, was consistently reported to be differentially expressed in six studies and the five most down-regulated miRNAs, miR-30a-3p, miR-139, miR-145, miR-125a and miR-133a, were consistently reported to be differentially expressed in four studies." tissue_expression_down hsa-mir-30a "Carcinoma, Rectal" 21671476 "One of the most up-regulated miRNAs, miRNA-106a, was consistently reported to be differentially expressed in six studies and the five most down-regulated miRNAs, miR-30a-3p, miR-139, miR-145, miR-125a and miR-133a, were consistently reported to be differentially expressed in four studies." tissue_expression_down hsa-mir-128-1 Alzheimer Disease 21686130 miR-128a/b levels were significantly reduced in the temporal cortex and miR-128b in the frontal cortex in AD. tissue_expression_down hsa-mir-128-2 Alzheimer Disease 21686130 miR-128a/b levels were significantly reduced in the temporal cortex and miR-128b in the frontal cortex in AD. tissue_expression_down hsa-mir-211 Melanoma 21687938 Downregulation of microRNA-211 is involved in expression of preferentially expressed antigen of melanoma in melanoma cells. tissue_expression_down hsa-mir-296 Heart Failure 21690488 "The absolute expression levels of hcmv-miR-UL112, miR-296-5p, and let-7e were further determined in 127 patients and 67 control subjects (fold changes are 2.5, 0.5, and 1.7 respectively; all P<0.0001)." tissue_expression_down hsa-mir-106a Prostate Neoplasms 21714127 The down-regulated miRs included miR-17-92 and miR-106ab clusters with well recognized oncogenic properties while the up-regulated miRs included several tumor suppressors tissue_expression_down hsa-mir-106b Prostate Neoplasms 21714127 The down-regulated miRs included miR-17-92 and miR-106ab clusters with well recognized oncogenic properties while the up-regulated miRs included several tumor suppressors tissue_expression_down hsa-mir-17 Prostate Neoplasms 21714127 The down-regulated miRs included miR-17-92 and miR-106ab clusters with well recognized oncogenic properties while the up-regulated miRs included several tumor suppressors tissue_expression_down hsa-mir-18 Prostate Neoplasms 21714127 The down-regulated miRs included miR-17-92 and miR-106ab clusters with well recognized oncogenic properties while the up-regulated miRs included several tumor suppressors tissue_expression_down hsa-mir-19a Prostate Neoplasms 21714127 The down-regulated miRs included miR-17-92 and miR-106ab clusters with well recognized oncogenic properties while the up-regulated miRs included several tumor suppressors tissue_expression_down hsa-mir-19b-1 Prostate Neoplasms 21714127 The down-regulated miRs included miR-17-92 and miR-106ab clusters with well recognized oncogenic properties while the up-regulated miRs included several tumor suppressors tissue_expression_down hsa-mir-20a Prostate Neoplasms 21714127 The down-regulated miRs included miR-17-92 and miR-106ab clusters with well recognized oncogenic properties while the up-regulated miRs included several tumor suppressors tissue_expression_down hsa-mir-92-1 Prostate Neoplasms 21714127 The down-regulated miRs included miR-17-92 and miR-106ab clusters with well recognized oncogenic properties while the up-regulated miRs included several tumor suppressors tissue_expression_down hsa-mir-221 Kaposi Sarcoma 21715310 "In the present study, we show that Kaposi sarcoma-associated herpesvirus (KSHV), the etiological agent of KS, induces global miRNA changes in lymphatic endothelial cells (LECs). Specifically, the miR-221/miR-222 cluster is down-regulated, whereas miR-31 is up-regulated." tissue_expression_down hsa-mir-222 Kaposi Sarcoma 21715310 "In the present study, we show that Kaposi sarcoma-associated herpesvirus (KSHV), the etiological agent of KS, induces global miRNA changes in lymphatic endothelial cells (LECs). Specifically, the miR-221/miR-222 cluster is down-regulated, whereas miR-31 is up-regulated." tissue_expression_down hsa-mir-21 "Carcinoma, Lung, Small-Cell" 21731696 "The authors observed significantly lower miR-21, miR-29b, and miR-34a expression in SCLC cell lines than in NSCLC cell lines." tissue_expression_down hsa-mir-29b-1 "Carcinoma, Lung, Small-Cell" 21731696 "The authors observed significantly lower miR-21, miR-29b, and miR-34a expression in SCLC cell lines than in NSCLC cell lines." tissue_expression_down hsa-mir-29b-2 "Carcinoma, Lung, Small-Cell" 21731696 "The authors observed significantly lower miR-21, miR-29b, and miR-34a expression in SCLC cell lines than in NSCLC cell lines." tissue_expression_down hsa-mir-34a "Carcinoma, Lung, Small-Cell" 21731696 "The authors observed significantly lower miR-21, miR-29b, and miR-34a expression in SCLC cell lines than in NSCLC cell lines." tissue_expression_down hsa-mir-1 "Carcinoma, Renal Cell" 21745735 Our data indicate that up-regulation of the oncogenic TAGLN2 was due to down-regulation of tumour-suppressive miR-1 and miR-133a in human RCC. tissue_expression_down hsa-mir-133a "Carcinoma, Renal Cell" 21745735 Our data indicate that up-regulation of the oncogenic TAGLN2 was due to down-regulation of tumour-suppressive miR-1 and miR-133a in human RCC. tissue_expression_down hsa-mir-122 "Carcinoma, Hepatocellular" 21750653 The down-regulation of miR-122 activated the CDK4-PSMD10-UPR pathway to decrease tumor cell anticancer drug-mediated apoptosis. tissue_expression_down hsa-mir-155 Melanoma 21763111 "Early steps in skin tumor formation in HPV8-CER mice were associated with an upregulation of the oncogenic miRNA-17-5p, -21 and -106a and a downregulation of the tumor-suppressive miRNA-155 and -206, which could be demonstrated by qPCR and in situ hybridization." tissue_expression_down hsa-mir-206 Melanoma 21763111 "Early steps in skin tumor formation in HPV8-CER mice were associated with an upregulation of the oncogenic miRNA-17-5p, -21 and -106a and a downregulation of the tumor-suppressive miRNA-155 and -206, which could be demonstrated by qPCR and in situ hybridization." tissue_expression_down hsa-mir-16-1 Lymphoma 21778999 Hypoxia-microRNA-16 downregulation induces VEGF expression in anaplastic lymphoma kinase (ALK)-positive anaplastic large-cell lymphomas. tissue_expression_down hsa-mir-16-2 Lymphoma 21778999 Hypoxia-microRNA-16 downregulation induces VEGF expression in anaplastic lymphoma kinase (ALK)-positive anaplastic large-cell lymphomas. tissue_expression_down hsa-mir-200c "Carcinoma, Renal Cell" 21784468 Underexpression tissue_expression_down hsa-mir-218-1 "Carcinoma, Renal Cell" 21784468 Underexpression tissue_expression_down hsa-mir-218-2 "Carcinoma, Renal Cell" 21784468 Underexpression tissue_expression_down hsa-mir-335 "Carcinoma, Renal Cell" 21784468 Underexpression tissue_expression_down hsa-mir-494 Cholangiocarcinoma 21809359 miRNA-494 downregulated in human cholangiocarcinoma controls cell cycle through multiple targets involved in the G1/S checkpoint. tissue_expression_down hsa-mir-143 Colorectal Carcinoma 21826996 downregulated in colon cancer compared to normal colonic mucosa tissue_expression_down hsa-mir-145 Colorectal Carcinoma 21826996 downregulated in colon cancer compared to normal colonic mucosa tissue_expression_down hsa-mir-214 Breast Neoplasms 21828058 "Decreased MicroRNA-214 Levels In Breast Cancer Cells Coincides with Increased Cell Proliferation, Invasion, and Accumulation of the Polycomb Ezh2 Methyltransferase." tissue_expression_down hsa-mir-146a "Carcinoma, Hepatocellular" 21829663 "miRNAs miR-26a, -29c, -146a and -190 were significantly down-regulated in a subset of HCC tissues with carboxyl-terminal HBx truncation compared to their matching non-tumor tissues." tissue_expression_down hsa-mir-190a "Carcinoma, Hepatocellular" 21829663 "miRNAs miR-26a, -29c, -146a and -190 were significantly down-regulated in a subset of HCC tissues with carboxyl-terminal HBx truncation compared to their matching non-tumor tissues." tissue_expression_down hsa-mir-26a-1 "Carcinoma, Hepatocellular" 21829663 "miRNAs miR-26a, -29c, -146a and -190 were significantly down-regulated in a subset of HCC tissues with carboxyl-terminal HBx truncation compared to their matching non-tumor tissues." tissue_expression_down hsa-mir-26a-2 "Carcinoma, Hepatocellular" 21829663 "miRNAs miR-26a, -29c, -146a and -190 were significantly down-regulated in a subset of HCC tissues with carboxyl-terminal HBx truncation compared to their matching non-tumor tissues." tissue_expression_down hsa-mir-29c "Carcinoma, Hepatocellular" 21829663 "miRNAs miR-26a, -29c, -146a and -190 were significantly down-regulated in a subset of HCC tissues with carboxyl-terminal HBx truncation compared to their matching non-tumor tissues." tissue_expression_down hsa-mir-145 Melanoma 21836381 "MiR-145 was significantly down-regulated in canine malignant melanoma tissues. The ectopic expression of miR-145 showed a significant growth inhibition in both canine and human melanoma cells tested, and the effect was achieved partly by suppressing c-MYC in canine melanoma LMeC, and human melanoma A2058 and Mewo cells." tissue_expression_down hsa-mir-195 "Carcinoma, Adrenocortical" 21859927 "Among others, miR-483-3p, miR-483-5p, miR-210, and miR-21 were found overexpressed,while miR-195, miR-497, and miR-1974 were underexpressed in ACC. " tissue_expression_down hsa-mir-1974 "Carcinoma, Adrenocortical" 21859927 "Among others, miR-483-3p, miR-483-5p, miR-210, and miR-21 were found overexpressed,while miR-195, miR-497, and miR-1974 were underexpressed in ACC. " tissue_expression_down hsa-mir-497 "Carcinoma, Adrenocortical" 21859927 "Among others, miR-483-3p, miR-483-5p, miR-210, and miR-21 were found overexpressed,while miR-195, miR-497, and miR-1974 were underexpressed in ACC. " tissue_expression_down hsa-mir-224 Colorectal Carcinoma 21864507 Underexpression in methotrexate resistant human colon cancer cells. tissue_expression_down hsa-let-7g Breast Neoplasms 21868760 "Treatment with estrogen or EGF specifically reduced the expression of mature let-7g through activation of p44/42 MAPK and subsequently stimulated expression of GAB2 and FN1, which in turn promoted tumor invasion. We thus identify let-7g as a unique member of the let-7 miRNA family which can serve as a prognostic biomarker in breast cancer and also propose a paradigm utilized by specific signaling molecules via let-7g to cooperatively promote breast cancer invasion and metastasis." tissue_expression_down hsa-mir-451a "Carcinoma, Lung, Non-Small-Cell" 21875770 "This study showed that miRNA-451 expression decreased in non-small cell lung cancer (NSCLC) tissues and that its expression was negatively associated with lymph node metastasis, the stage of TNM classification and poor prognosis of NSCLC patients. Moreover, significantly different miRNA-451 expression levels were found between smoking and non-smoking patients. The overexpression of miRNA-451 inhibited cell cycle progression, cellular migration and the invasive ability of NSCLC cells.Increased miRNA-451 expression also promoted anoikis of NSCLC cells." tissue_expression_down hsa-mir-221 "Carcinoma, Hepatocellular" 21876625 "downregulated in acute HBV infection, normally expressed in chronic HBV infection, and upregulated in HCC" tissue_expression_down hsa-mir-221 Hepatitis B Virus Infection 21876625 "downregulated in acute HBV infection, normally expressed in chronic HBV infection, and upregulated in HCC" tissue_expression_down hsa-mir-99a "Carcinoma, Hepatocellular" 21878637 "Lower miR-99a expression in HCC tissues significantly correlated with shorter survival of HCC patients, and miR-99a was identified to be an independent predictor for prognosis of HCC patients. Furthermore, restoration of miR-99a dramatically suppressed HCC cell growth in vitro by inducing G1 phase cell cycle arrest." tissue_expression_down hsa-let-7c Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-100 Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-143 Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-145 Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-146a Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-15a Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-16-1 Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-16-2 Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-191 Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-199a-1 Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-199a-2 Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-218-1 Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-25 Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-32 Prostate Neoplasms 21880514 significantly changed during the progression of cancer tissue_expression_down hsa-mir-146a Diabetes Mellitus 21885871 "A total of 25 mmol/L glucose decreased miR-146a expression and increased FN expression compared with 5 mmol/L glucose in both cell types. miR-146a mimic transfection prevented such change, whereas miR-146a antagomir transfection in the cells in 5 mmol/L glucose caused FN upregulation. A luciferase assay confirmed miR-146a's binding to FN 3'-UTR. miR-146a was localized in the retinal endothelial cells and was decreased in diabetes. Intravitreal miR-146a mimic injection restored retinal miR-146a and increased FN in diabetes. Additional experiments showed that p300 regulates miR-146a." tissue_expression_down hsa-mir-124-1 Glioblastoma 21912681 Significantly down-regulated in glioblastomas. tissue_expression_down hsa-mir-124-2 Glioblastoma 21912681 Significantly down-regulated in glioblastomas. tissue_expression_down hsa-mir-124-3 Glioblastoma 21912681 Significantly down-regulated in glioblastomas. tissue_expression_down hsa-mir-128-1 Glioblastoma 21912681 Significantly down-regulated in glioblastomas. tissue_expression_down hsa-mir-128-2 Glioblastoma 21912681 Significantly down-regulated in glioblastomas. tissue_expression_down hsa-mir-139 Glioblastoma 21912681 Significantly down-regulated in glioblastomas. tissue_expression_down hsa-mir-7-1 Glioblastoma 21912681 Significantly down-regulated in glioblastomas. tissue_expression_down hsa-mir-7-2 Glioblastoma 21912681 Significantly down-regulated in glioblastomas. tissue_expression_down hsa-mir-7-3 Glioblastoma 21912681 Significantly down-regulated in glioblastomas. tissue_expression_down hsa-mir-873 Glioblastoma 21912681 Significantly down-regulated in glioblastomas. tissue_expression_down hsa-mir-95 Glioblastoma 21912681 Significantly down-regulated in glioblastomas. tissue_expression_down hsa-mir-146a Asthma 21917308 Measurement of the microRNA expression profile showed selective downregulation of miR-28-5p in CD8(+) T cells and reduction of miR-146a and miR-146b in both CD4(+) and CD8(+) T cells. tissue_expression_down hsa-mir-146b Asthma 21917308 Measurement of the microRNA expression profile showed selective downregulation of miR-28-5p in CD8(+) T cells and reduction of miR-146a and miR-146b in both CD4(+) and CD8(+) T cells. tissue_expression_down hsa-mir-28 Asthma 21917308 Measurement of the microRNA expression profile showed selective downregulation of miR-28-5p in CD8(+) T cells and reduction of miR-146a and miR-146b in both CD4(+) and CD8(+) T cells. tissue_expression_down hsa-mir-101-1 "Lymphoma, T-Cell" 21921041 "Re-expression of downregulated miRNAs, such as mir-101, mir-26a, mir26b, mir-28-5 and mir-363, reduced the growth of NK cell line and modulated the expression of their predicted target genes." tissue_expression_down hsa-mir-101-2 "Lymphoma, T-Cell" 21921041 "Re-expression of downregulated miRNAs, such as mir-101, mir-26a, mir26b, mir-28-5 and mir-363, reduced the growth of NK cell line and modulated the expression of their predicted target genes." tissue_expression_down hsa-mir-26a-1 "Lymphoma, T-Cell" 21921041 "Re-expression of downregulated miRNAs, such as mir-101, mir-26a, mir26b, mir-28-5 and mir-363, reduced the growth of NK cell line and modulated the expression of their predicted target genes." tissue_expression_down hsa-mir-26a-2 "Lymphoma, T-Cell" 21921041 "Re-expression of downregulated miRNAs, such as mir-101, mir-26a, mir26b, mir-28-5 and mir-363, reduced the growth of NK cell line and modulated the expression of their predicted target genes." tissue_expression_down hsa-mir-26b "Lymphoma, T-Cell" 21921041 "Re-expression of downregulated miRNAs, such as mir-101, mir-26a, mir26b, mir-28-5 and mir-363, reduced the growth of NK cell line and modulated the expression of their predicted target genes." tissue_expression_down hsa-mir-127 Colorectal Carcinoma 21922590 "The presence of the KRAS mutation was associated with up-regulation of miR-127-3p, miR-92a, and miR-486-3p and down-regulation of miR-378." tissue_expression_down hsa-mir-486 Colorectal Carcinoma 21922590 "The presence of the KRAS mutation was associated with up-regulation of miR-127-3p, miR-92a, and miR-486-3p and down-regulation of miR-378." tissue_expression_down hsa-mir-92a-1 Colorectal Carcinoma 21922590 "The presence of the KRAS mutation was associated with up-regulation of miR-127-3p, miR-92a, and miR-486-3p and down-regulation of miR-378." tissue_expression_down hsa-mir-92a-2 Colorectal Carcinoma 21922590 "The presence of the KRAS mutation was associated with up-regulation of miR-127-3p, miR-92a, and miR-486-3p and down-regulation of miR-378." tissue_expression_down hsa-mir-106a Medulloblastoma 21931624 hsa-mir-106a* was significantly down-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_down hsa-mir-10a Medulloblastoma 21931624 hsa-mir-10a was significantly down-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_down hsa-mir-219 Medulloblastoma 21931624 hsa-mir-219-5p was significantly down-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_down hsa-mir-219-1 Medulloblastoma 21931624 hsa-mir-219-1-3p was significantly down-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_down hsa-mir-302b Medulloblastoma 21931624 hsa-mir-302b* was significantly down-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_down hsa-mir-302d Medulloblastoma 21931624 hsa-mir-302d* was significantly down-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_down hsa-mir-373 Medulloblastoma 21931624 hsa-mir-373 was significantly down-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_down hsa-mir-483 Medulloblastoma 21931624 hsa-mir-483-5p was significantly down-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_down hsa-mir-504 Medulloblastoma 21931624 hsa-mir-504 was significantly down-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_down hsa-mir-92b Medulloblastoma 21931624 hsa-mir-92b* was significantly down-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_down hsa-mir-935 Medulloblastoma 21931624 hsa-mir-935 was significantly down-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_down hsa-mir-122 Asthenozoospermia 21933900 miR-122 was markedly decreased in azoospermia but increased in asthenozoospermia. tissue_expression_down hsa-mir-146b Asthenozoospermia 21933900 miR-146b was markedly decreased in azoospermia but increased in asthenozoospermia. tissue_expression_down hsa-mir-181a-2 Asthenozoospermia 21933900 miR-181a was markedly decreased in azoospermia but increased in asthenozoospermia. tissue_expression_down hsa-mir-34c Asthenozoospermia 21933900 miR-34c-5p was markedly decreased in azoospermia but increased in asthenozoospermia. tissue_expression_down hsa-mir-374b Asthenozoospermia 21933900 miR-374b was markedly decreased in azoospermia but increased in asthenozoospermia. tissue_expression_down hsa-mir-509-1 Asthenozoospermia 21933900 miR-509-5p was markedly decreased in azoospermia but increased in asthenozoospermia. tissue_expression_down hsa-mir-509-2 Asthenozoospermia 21933900 miR-509-5p was markedly decreased in azoospermia but increased in asthenozoospermia. tissue_expression_down hsa-mir-509-3 Asthenozoospermia 21933900 miR-509-5p was markedly decreased in azoospermia but increased in asthenozoospermia. tissue_expression_down hsa-mir-513a-1 Asthenozoospermia 21933900 miR-513a-5p was markedly decreased in azoospermia but increased in asthenozoospermia. tissue_expression_down hsa-mir-513a-2 Asthenozoospermia 21933900 miR-513a-5p was markedly decreased in azoospermia but increased in asthenozoospermia. tissue_expression_down hsa-let-7c Ovarian Neoplasms 21939554 The miRNA was downregulated in cis-platin resistant (A2780/CP70) vs. cis-platin sensitive (A2780) ovarian cancer cell lines. tissue_expression_down hsa-mir-20b Ovarian Neoplasms 21939554 The miRNA was downregulated in cis-platin resistant (A2780/CP70) vs. cis-platin sensitive (A2780) ovarian cancer cell lines. tissue_expression_down hsa-mir-542 Ovarian Neoplasms 21939554 The miRNA hsa-miR-542-3p was downregulated in cis-platin resistant (A2780/CP70) vs. cis-platin sensitive (A2780) ovarian cancer cell lines. tissue_expression_down hsa-mir-625 Ovarian Neoplasms 21939554 The miRNA was downregulated in cis-platin resistant (A2780/CP70) vs. cis-platin sensitive (A2780) ovarian cancer cell lines. tissue_expression_down hsa-mir-125b-1 Lichen Planus 21943223 "Increased expression of miR-21 and miR-203, decreased expression of miR-125, and down-regulation of p53 and deltaNp63 RNA were seen in OLP compared to normal oral mucosa. When comparing microRNA expression to levels of p53 and p63 RNA, a significant negative correlation was seen between deltaNp63 and miR-203 and between miR-21 and p53, respectively." tissue_expression_down hsa-mir-125b-2 Lichen Planus 21943223 "Increased expression of miR-21 and miR-203, decreased expression of miR-125, and down-regulation of p53 and deltaNp63 RNA were seen in OLP compared to normal oral mucosa. When comparing microRNA expression to levels of p53 and p63 RNA, a significant negative correlation was seen between deltaNp63 and miR-203 and between miR-21 and p53, respectively." tissue_expression_down hsa-mir-10b Breast Neoplasms 21953071 The miRNA was down-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_down hsa-mir-139 Breast Neoplasms 21953071 The miRNA was down-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_down hsa-mir-140 Breast Neoplasms 21953071 The miRNA was down-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_down hsa-mir-224 Breast Neoplasms 21953071 The miRNA was down-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_down hsa-mir-365a Breast Neoplasms 21953071 The miRNA was down-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_down hsa-mir-365b Breast Neoplasms 21953071 The miRNA was down-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_down hsa-mir-450a-1 Breast Neoplasms 21953071 The miRNA was down-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_down hsa-mir-450a-2 Breast Neoplasms 21953071 The miRNA was down-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_down hsa-mir-450b Breast Neoplasms 21953071 The miRNA was down-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_down hsa-mir-100 Pancreatic Neoplasms 21953293 Highly down-regulated in PDAC compared with normal ductal tissue_expression_down hsa-mir-145 Pancreatic Neoplasms 21953293 Highly down-regulated in PDAC compared with normal ductal tissue_expression_down hsa-mir-148a Pancreatic Neoplasms 21953293 Highly down-regulated in PDAC compared with normal ductal tissue_expression_down hsa-mir-199b Pancreatic Neoplasms 21953293 miR-199b-5p: Highly down-regulated in PDAC compared with normal ductal tissue_expression_down hsa-mir-451a Pancreatic Neoplasms 21953293 Highly down-regulated in PDAC compared with normal ductal tissue_expression_down hsa-mir-101-1 Lymphoma 21960592 "The down-regulation of miR-16, miR-26a, miR-101, miR-29c and miR138 in the t(14;18)-negative FL( follicular lymphoma ) subset was associated with profound mRNA expression changes of potential target genes involving cell cycle control, apoptosis and B-cell differentiation. miR-16 target CHEK1 showed increased expression on the protein level in t(14;18)-negative FL, while TCL1A expression was reduced, in line with a partial loss of the germinal center B-cell phenotype in this FL subset." tissue_expression_down hsa-mir-101-2 Lymphoma 21960592 "The down-regulation of miR-16, miR-26a, miR-101, miR-29c and miR138 in the t(14;18)-negative FL( follicular lymphoma ) subset was associated with profound mRNA expression changes of potential target genes involving cell cycle control, apoptosis and B-cell differentiation. miR-16 target CHEK1 showed increased expression on the protein level in t(14;18)-negative FL, while TCL1A expression was reduced, in line with a partial loss of the germinal center B-cell phenotype in this FL subset." tissue_expression_down hsa-mir-138-1 Lymphoma 21960592 "The down-regulation of miR-16, miR-26a, miR-101, miR-29c and miR138 in the t(14;18)-negative FL( follicular lymphoma ) subset was associated with profound mRNA expression changes of potential target genes involving cell cycle control, apoptosis and B-cell differentiation. miR-16 target CHEK1 showed increased expression on the protein level in t(14;18)-negative FL, while TCL1A expression was reduced, in line with a partial loss of the germinal center B-cell phenotype in this FL subset." tissue_expression_down hsa-mir-138-2 Lymphoma 21960592 "The down-regulation of miR-16, miR-26a, miR-101, miR-29c and miR138 in the t(14;18)-negative FL( follicular lymphoma ) subset was associated with profound mRNA expression changes of potential target genes involving cell cycle control, apoptosis and B-cell differentiation. miR-16 target CHEK1 showed increased expression on the protein level in t(14;18)-negative FL, while TCL1A expression was reduced, in line with a partial loss of the germinal center B-cell phenotype in this FL subset." tissue_expression_down hsa-mir-16-1 Lymphoma 21960592 "The down-regulation of miR-16, miR-26a, miR-101, miR-29c and miR138 in the t(14;18)-negative FL( follicular lymphoma ) subset was associated with profound mRNA expression changes of potential target genes involving cell cycle control, apoptosis and B-cell differentiation. miR-16 target CHEK1 showed increased expression on the protein level in t(14;18)-negative FL, while TCL1A expression was reduced, in line with a partial loss of the germinal center B-cell phenotype in this FL subset." tissue_expression_down hsa-mir-16-2 Lymphoma 21960592 "The down-regulation of miR-16, miR-26a, miR-101, miR-29c and miR138 in the t(14;18)-negative FL( follicular lymphoma ) subset was associated with profound mRNA expression changes of potential target genes involving cell cycle control, apoptosis and B-cell differentiation. miR-16 target CHEK1 showed increased expression on the protein level in t(14;18)-negative FL, while TCL1A expression was reduced, in line with a partial loss of the germinal center B-cell phenotype in this FL subset." tissue_expression_down hsa-mir-29c Lymphoma 21960592 "The down-regulation of miR-16, miR-26a, miR-101, miR-29c and miR138 in the t(14;18)-negative FL( follicular lymphoma ) subset was associated with profound mRNA expression changes of potential target genes involving cell cycle control, apoptosis and B-cell differentiation. miR-16 target CHEK1 showed increased expression on the protein level in t(14;18)-negative FL, while TCL1A expression was reduced, in line with a partial loss of the germinal center B-cell phenotype in this FL subset." tissue_expression_down hsa-let-7a-1 Mycosis Fungoides 21966986 "MiR-155 was only found to be slightly overexpressed in MF compared to healthy controls. Furthermore, metastatic MF demonstrated lower concentrations of let-7a, let-7d and let-7f when compared to MF limited to the skin." tissue_expression_down hsa-let-7a-2 Mycosis Fungoides 21966986 "MiR-155 was only found to be slightly overexpressed in MF compared to healthy controls. Furthermore, metastatic MF demonstrated lower concentrations of let-7a, let-7d and let-7f when compared to MF limited to the skin." tissue_expression_down hsa-let-7a-3 Mycosis Fungoides 21966986 "MiR-155 was only found to be slightly overexpressed in MF compared to healthy controls. Furthermore, metastatic MF demonstrated lower concentrations of let-7a, let-7d and let-7f when compared to MF limited to the skin." tissue_expression_down hsa-let-7d Mycosis Fungoides 21966986 "MiR-155 was only found to be slightly overexpressed in MF compared to healthy controls. Furthermore, metastatic MF demonstrated lower concentrations of let-7a, let-7d and let-7f when compared to MF limited to the skin." tissue_expression_down hsa-let-7f-1 Mycosis Fungoides 21966986 "MiR-155 was only found to be slightly overexpressed in MF compared to healthy controls. Furthermore, metastatic MF demonstrated lower concentrations of let-7a, let-7d and let-7f when compared to MF limited to the skin." tissue_expression_down hsa-let-7f-2 Mycosis Fungoides 21966986 "MiR-155 was only found to be slightly overexpressed in MF compared to healthy controls. Furthermore, metastatic MF demonstrated lower concentrations of let-7a, let-7d and let-7f when compared to MF limited to the skin." tissue_expression_down hsa-mir-21 Ovarian Neoplasms 21968270 miR-21 down-regulation promotes apoptosis and inhibits invasion and migration abilities of OVCAR3 (ovarian papillary adenocarcinoma cell lines) cells. tissue_expression_down hsa-mir-138-1 "Squamous Cell Carcinoma, Head and Neck" 21969367 "In this study, the authors first confirm the microRNA-138-mediated down-regulation of FOSL1 in squamous cell carcinoma (SCC) cell lines." tissue_expression_down hsa-mir-138-2 "Squamous Cell Carcinoma, Head and Neck" 21969367 "In this study, the authors first confirm the microRNA-138-mediated down-regulation of FOSL1 in squamous cell carcinoma (SCC) cell lines." tissue_expression_down hsa-mir-410 Neuroblastoma 21970883 "Two, miR-487b and miR-410, were significantly downregulated in the high-risk group. Multivariable analyses showed miR-487b expression as associated with overall survival and disease-free survival in the whole cohort, independently of clinical covariates. Moreover, miR-487b and miR-410 expression was significantly associated with disease-free survival of the non-MYCN-amplified favourable neuroblastoma: localised (stage 1, 2 and 3) and stage 4 of infant <18 months.Conclusion:Expression of miR-487b and miR-410 shows predictive value beyond the classical high-/low-risk stratification and is a biomarker of relapse in favourable neuroblastoma." tissue_expression_down hsa-mir-487b Neuroblastoma 21970883 "Two, miR-487b and miR-410, were significantly downregulated in the high-risk group. Multivariable analyses showed miR-487b expression as associated with overall survival and disease-free survival in the whole cohort, independently of clinical covariates. Moreover, miR-487b and miR-410 expression was significantly associated with disease-free survival of the non-MYCN-amplified favourable neuroblastoma: localised (stage 1, 2 and 3) and stage 4 of infant <18 months.Conclusion:Expression of miR-487b and miR-410 shows predictive value beyond the classical high-/low-risk stratification and is a biomarker of relapse in favourable neuroblastoma." tissue_expression_down hsa-mir-107 Astrocytoma 21978395 "miR-107, miR-124, miR-138, and miR-149 were downregulated significantly in grade I-IV astrocytomas, and overexpression of miR-124 and miR-149 inhibited glioblastoma cell proliferation and migration." tissue_expression_down hsa-mir-124-1 Astrocytoma 21978395 "miR-107, miR-124, miR-138, and miR-149 were downregulated significantly in grade I-IV astrocytomas, and overexpression of miR-124 and miR-149 inhibited glioblastoma cell proliferation and migration." tissue_expression_down hsa-mir-124-2 Astrocytoma 21978395 "miR-107, miR-124, miR-138, and miR-149 were downregulated significantly in grade I-IV astrocytomas, and overexpression of miR-124 and miR-149 inhibited glioblastoma cell proliferation and migration." tissue_expression_down hsa-mir-124-3 Astrocytoma 21978395 "miR-107, miR-124, miR-138, and miR-149 were downregulated significantly in grade I-IV astrocytomas, and overexpression of miR-124 and miR-149 inhibited glioblastoma cell proliferation and migration." tissue_expression_down hsa-mir-138-1 Astrocytoma 21978395 "miR-107, miR-124, miR-138, and miR-149 were downregulated significantly in grade I-IV astrocytomas, and overexpression of miR-124 and miR-149 inhibited glioblastoma cell proliferation and migration." tissue_expression_down hsa-mir-138-2 Astrocytoma 21978395 "miR-107, miR-124, miR-138, and miR-149 were downregulated significantly in grade I-IV astrocytomas, and overexpression of miR-124 and miR-149 inhibited glioblastoma cell proliferation and migration." tissue_expression_down hsa-mir-149 Astrocytoma 21978395 "miR-107, miR-124, miR-138, and miR-149 were downregulated significantly in grade I-IV astrocytomas, and overexpression of miR-124 and miR-149 inhibited glioblastoma cell proliferation and migration." tissue_expression_down hsa-mir-1290 "Carcinoma, Hepatocellular" 21998738 hsa-mir-1290 was down-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_down hsa-mir-187 "Carcinoma, Hepatocellular" 21998738 hsa-mir-187* was down-regulated in HepG2 cells after 5 hours of culture with cocoa proanthocyanidin extract. tissue_expression_down hsa-mir-2110 "Carcinoma, Hepatocellular" 21998738 hsa-mir-2110 was down-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_down hsa-mir-30b "Carcinoma, Hepatocellular" 21998738 hsa-mir-30b* was down-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_down hsa-mir-320c-1 "Carcinoma, Hepatocellular" 21998738 hsa-mir-320c was down-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_down hsa-mir-320c-2 "Carcinoma, Hepatocellular" 21998738 hsa-mir-320c was down-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_down hsa-mir-323b "Carcinoma, Hepatocellular" 21998738 hsa-mir-453 (note: this miRNA was replaced by hsa-mir-323b) was down-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_down hsa-mir-483 "Carcinoma, Hepatocellular" 21998738 hsa-mir-483-5p was down-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_down hsa-mir-520e "Carcinoma, Hepatocellular" 21998738 hsa-mir-520e was down-regulated in HepG2 cells after 5 hours of culture with epigallocatechin gallate. tissue_expression_down hsa-mir-608 "Carcinoma, Hepatocellular" 21998738 hsa-mir-608 was down-regulated in HepG2 cells after 5 hours of culture with epigallocatechin gallate. tissue_expression_down hsa-mir-629 "Carcinoma, Hepatocellular" 21998738 hsa-mir-629 was down-regulated in HepG2 cells after 5 hours of culture with epigallocatechin gallate. tissue_expression_down hsa-mir-765 "Carcinoma, Hepatocellular" 21998738 hsa-mir-765 was down-regulated in HepG2 cells after 5 hours of culture with cocoa proanthocyanidin extract. tissue_expression_down hsa-mir-1-1 "Aortic Aneurysm, Thoracic" 22010139 "miRs -1, -21, -29a, -133a, and -486 showed decreased expression in Thoracic Aortic Aneurysm compared to normal aortic specimens.A significant relationship between miR expression levels (miRs -1, -21, -29a, and -133a) and aortic diameter was identified;" tissue_expression_down hsa-mir-1-2 "Aortic Aneurysm, Thoracic" 22010139 "miRs -1, -21, -29a, -133a, and -486 showed decreased expression in Thoracic Aortic Aneurysm compared to normal aortic specimens.A significant relationship between miR expression levels (miRs -1, -21, -29a, and -133a) and aortic diameter was identified;" tissue_expression_down hsa-mir-133a-1 "Aortic Aneurysm, Thoracic" 22010139 "miRs -1, -21, -29a, -133a, and -486 showed decreased expression in Thoracic Aortic Aneurysm compared to normal aortic specimens.A significant relationship between miR expression levels (miRs -1, -21, -29a, and -133a) and aortic diameter was identified;" tissue_expression_down hsa-mir-133a-2 "Aortic Aneurysm, Thoracic" 22010139 "miRs -1, -21, -29a, -133a, and -486 showed decreased expression in Thoracic Aortic Aneurysm compared to normal aortic specimens.A significant relationship between miR expression levels (miRs -1, -21, -29a, and -133a) and aortic diameter was identified;" tissue_expression_down hsa-mir-21 "Aortic Aneurysm, Thoracic" 22010139 "miRs -1, -21, -29a, -133a, and -486 showed decreased expression in Thoracic Aortic Aneurysm compared to normal aortic specimens.A significant relationship between miR expression levels (miRs -1, -21, -29a, and -133a) and aortic diameter was identified;" tissue_expression_down hsa-mir-29a "Aortic Aneurysm, Thoracic" 22010139 "miRs -1, -21, -29a, -133a, and -486 showed decreased expression in Thoracic Aortic Aneurysm compared to normal aortic specimens.A significant relationship between miR expression levels (miRs -1, -21, -29a, and -133a) and aortic diameter was identified;" tissue_expression_down hsa-mir-26b Lichen Planus 22017396 Levels of COX-2 mRNA were significantly higher while levels of miR-26b were significantly lower in OLP lesions compared to controls. Increased expression of COX-2 and decreased expression of miR-26b in OLP suggests both to play a role in OLP. tissue_expression_down hsa-mir-107 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-125a "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-125b-1 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-125b-2 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-133b "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-134 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-139 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-144 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-150 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-151a "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-181c "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-18a "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-195 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-197 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-200a "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-202 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-208a "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-208b "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-212 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-214 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-223 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-24-1 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-24-2 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-296 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-30d "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-320a "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-320b-1 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-320b-2 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-320c-1 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-320d-1 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-320e "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-324 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-326 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-330 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-345 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-346 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-361 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-365a "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-365b "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-370 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-373 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-378a "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-381 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-409 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-423 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-483 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-484 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-485 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-486 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-489 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-490 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-492 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-498 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-500a "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-500b "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-503 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-518b "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-520d "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-526a-1 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-526a-2 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-526b "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-527 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-542 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-92a-1 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-92a-2 "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-92b "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-99b "Carcinoma, Hepatocellular" 22027761 This miRNA was down-regulated in HepG2 cells treated with BJA32515. tissue_expression_down hsa-mir-15a "Carcinoma, Hepatocellular" 22033921 The microRNA 15/16 cluster downregulates protein repair isoaspartyl methyltransferase in hepatoma cells. The authors conclude that PCMT is effectively regulated by the miR15a-16-1 cluster and is involved in apoptosis by preserving the structural stability and biological function of BclxL from deamidation. Control of PCMT expression by snRNAs may thus represent a late check point in apoptosis regulation. tissue_expression_down hsa-mir-16-1 "Carcinoma, Hepatocellular" 22033921 The microRNA 15/16 cluster downregulates protein repair isoaspartyl methyltransferase in hepatoma cells. The authors conclude that PCMT is effectively regulated by the miR15a-16-1 cluster and is involved in apoptosis by preserving the structural stability and biological function of BclxL from deamidation. Control of PCMT expression by snRNAs may thus represent a late check point in apoptosis regulation. tissue_expression_down hsa-let-7i "Cardiomyopathy, Dilated" 22041329 "Levels of let-7i, miR-126, and miR-155 were lower in the DCM group than in the controls, whereas levels of miR-21 and TLR4 (both mRNA and protein) were higher in the DCM group than in the control group. Levels of let-7i were negatively correlated with TLR4 protein levels in all subjects. After a mean follow-up period of 509 days, 6 DCM patients (5.8%) had died due to a cardiac cause and 15 (14.6%) had developed heart failure. When patients with DCM were divided into tertiles according to let-7i levels, log-rank analysis showed that the DCM subgroup with low let-7i levels was associated with poor clinical outcomes (P = .02)." tissue_expression_down hsa-mir-126 "Cardiomyopathy, Dilated" 22041329 "Levels of let-7i, miR-126, and miR-155 were lower in the DCM group than in the controls, whereas levels of miR-21 and TLR4 (both mRNA and protein) were higher in the DCM group than in the control group. Levels of let-7i were negatively correlated with TLR4 protein levels in all subjects. After a mean follow-up period of 509 days, 6 DCM patients (5.8%) had died due to a cardiac cause and 15 (14.6%) had developed heart failure. When patients with DCM were divided into tertiles according to let-7i levels, log-rank analysis showed that the DCM subgroup with low let-7i levels was associated with poor clinical outcomes (P = .02)." tissue_expression_down hsa-mir-155 "Cardiomyopathy, Dilated" 22041329 "Levels of let-7i, miR-126, and miR-155 were lower in the DCM group than in the controls, whereas levels of miR-21 and TLR4 (both mRNA and protein) were higher in the DCM group than in the control group. Levels of let-7i were negatively correlated with TLR4 protein levels in all subjects. After a mean follow-up period of 509 days, 6 DCM patients (5.8%) had died due to a cardiac cause and 15 (14.6%) had developed heart failure. When patients with DCM were divided into tertiles according to let-7i levels, log-rank analysis showed that the DCM subgroup with low let-7i levels was associated with poor clinical outcomes (P = .02)." tissue_expression_down hsa-mir-150 Myocardial Infarction 22048267 "Comparing MI patients with VR and those without VR, we found miR-146a up-regulation, and miR-150 and miR-155 down-regulation in patients with VR. In conclusion, our study demonstrated an altered expression of miR-146a, miR-150, and miR-155 in MI compared to the normal hearts." tissue_expression_down hsa-mir-155 Myocardial Infarction 22048267 "Comparing MI patients with VR and those without VR, we found miR-146a up-regulation, and miR-150 and miR-155 down-regulation in patients with VR. In conclusion, our study demonstrated an altered expression of miR-146a, miR-150, and miR-155 in MI compared to the normal hearts." tissue_expression_down hsa-mir-383 Ependymoma 22053178 underexpression tissue_expression_down hsa-mir-485 Ependymoma 22053178 miR-485-5p: underexpression tissue_expression_down hsa-mir-365a Colon Neoplasms 22072615 "microRNA-365, down-regulated in colon cancer, inhibits cell cycle progression and promotes apoptosis of colon cancer cells by probably targeting Cyclin D1 and Bcl-2." tissue_expression_down hsa-let-7a-1 Glioblastoma 22074483 "Significantly deregulated miRNAs were miR-3163 (fold change 2.0, p = 0.05), miR-539 (fold change 0.5, p = 0.001), miR-1305 (fold change 0.5, p = 0.05), miR-1260 (fold change 0.5, p = 0.03) and let-7a (fold change 0.3, p = 0.02) after temozolomide treatment." tissue_expression_down hsa-let-7a-2 Glioblastoma 22074483 "Significantly deregulated miRNAs were miR-3163 (fold change 2.0, p = 0.05), miR-539 (fold change 0.5, p = 0.001), miR-1305 (fold change 0.5, p = 0.05), miR-1260 (fold change 0.5, p = 0.03) and let-7a (fold change 0.3, p = 0.02) after temozolomide treatment." tissue_expression_down hsa-let-7a-3 Glioblastoma 22074483 "Significantly deregulated miRNAs were miR-3163 (fold change 2.0, p = 0.05), miR-539 (fold change 0.5, p = 0.001), miR-1305 (fold change 0.5, p = 0.05), miR-1260 (fold change 0.5, p = 0.03) and let-7a (fold change 0.3, p = 0.02) after temozolomide treatment." tissue_expression_down hsa-mir-1260a Glioblastoma 22074483 "Significantly deregulated miRNAs were miR-3163 (fold change 2.0, p = 0.05), miR-539 (fold change 0.5, p = 0.001), miR-1305 (fold change 0.5, p = 0.05), miR-1260 (fold change 0.5, p = 0.03) and let-7a (fold change 0.3, p = 0.02) after temozolomide treatment." tissue_expression_down hsa-mir-1305 Glioblastoma 22074483 "Significantly deregulated miRNAs were miR-3163 (fold change 2.0, p = 0.05), miR-539 (fold change 0.5, p = 0.001), miR-1305 (fold change 0.5, p = 0.05), miR-1260 (fold change 0.5, p = 0.03) and let-7a (fold change 0.3, p = 0.02) after temozolomide treatment." tissue_expression_down hsa-mir-539 Glioblastoma 22074483 "Significantly deregulated miRNAs were miR-3163 (fold change 2.0, p = 0.05), miR-539 (fold change 0.5, p = 0.001), miR-1305 (fold change 0.5, p = 0.05), miR-1260 (fold change 0.5, p = 0.03) and let-7a (fold change 0.3, p = 0.02) after temozolomide treatment." tissue_expression_down hsa-mir-27b Lichen Planus 22077423 "miR-27b was significantly down-regulated in OLP tissue, and miR-27b expression was even more suppressed in atrophic-erosive OLP than in reticular OLP. In addition, miR-27b was found to be expressed in the epithelial keratinocyte layer of both normal and OLP tissues." tissue_expression_down hsa-mir-449a "Carcinoma, Lung, Non-Small-Cell" 22078727 "miR-449a/b was significantly down-regulated in lung cancer tissues compared with normal lung tissues, while HDAC1 was up-regulated in lung cancer tissues.Combined treatment with miR-449a and HDAC inhibitors (apicidin and TSA) in HCC95 cells showed a significant growth reduction compared to mono-treatment with HDAC inhibitors. Interestingly, combination treatment with TSA and miR-449a was had significant growth reduction than a combination with apicidin." tissue_expression_down hsa-mir-449b "Carcinoma, Lung, Non-Small-Cell" 22078727 "miR-449a/b was significantly down-regulated in lung cancer tissues compared with normal lung tissues, while HDAC1 was up-regulated in lung cancer tissues.Combined treatment with miR-449a and HDAC inhibitors (apicidin and TSA) in HCC95 cells showed a significant growth reduction compared to mono-treatment with HDAC inhibitors. Interestingly, combination treatment with TSA and miR-449a was had significant growth reduction than a combination with apicidin." tissue_expression_down hsa-mir-218-1 Glioma 22088371 "The expression level of miR-218 is an important reference indicator for the assessment of the grade of gliomas. An aberrant decrease of its expression may lead to an increase of the CDK6 expression and proliferative activity of giloma cells. Introducing exogenous miR-218 may effectively down-regulate the CDK6 expression, inhibit cell proliferation and induce apoptosis of malignant giloma cells." tissue_expression_down hsa-mir-218-2 Glioma 22088371 "The expression level of miR-218 is an important reference indicator for the assessment of the grade of gliomas. An aberrant decrease of its expression may lead to an increase of the CDK6 expression and proliferative activity of giloma cells. Introducing exogenous miR-218 may effectively down-regulate the CDK6 expression, inhibit cell proliferation and induce apoptosis of malignant giloma cells." tissue_expression_down hsa-mir-203 Barrett Esophagus 22094011 "We demonstrated unequivocal statistically significant upregulation of two microRNAs (miR-192, 196a) and downregulation of miR-203 and positive miR-196a correlation with progression from intestinal metaplasia to adenocarcinoma compared to normal individuals." tissue_expression_down hsa-mir-200c Breast Neoplasms 22101791 "Down-regulation of microRNA-200c is associated with drug resistance in human breast cancer.Down-regulated miR-200c was observed in non-responders as compared to responders. In addition, miR-200c expression was observed to be down-regulated over 800-fold in human breast cancer cells resistant to doxorubicin MCF-7/ADR as compared to the parental MCF-7 cells. Up-regulation of miR-200c with transfection of miR-200c mimics in breast cancer cells could enhance the chemosensitivity to epirubicin and reduce expression of multidrug resistance 1 mRNA and P-glycoprotein. Moreover, our study demonstrated that restoration of miR-200c in MCF-7/ADR cells could increase intracellular doxorubicin accumulation determined by flow cytometry." tissue_expression_down hsa-mir-34a Pancreatic Neoplasms 22114136 "In the initial cohort of 48 PDAC (pancreatic ductal adenocarcinoma) patients, high expression of miR-21 (Hazard ratio (HR): 3.22, 95% Confidence Interval (CI):1.21-8.58) and reduced expression of miR-34a (HR 0.15, 95%CI: 0.06-0.37) and miR-30d (HR:0.30, 95%CI:0.12-0.79) were associated with poor overall survival following resection independent of clinical covariates. In a further validation set of 24 patients miR-21 and miR-34a expression again significantly correlated with overall survival (P = 0.031 and P = 0.001)." tissue_expression_down hsa-mir-206 Colorectal Carcinoma 22120473 "Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases." tissue_expression_down hsa-mir-221 Prostate Neoplasms 22127852 The altered expression of MiR-221/-222 (increased miR-221/-222 expression ) and MiR-23b/-27b (down-regulated ) is associated with the development of human castration resistant prostate cancer. tissue_expression_down hsa-mir-222 Prostate Neoplasms 22127852 The altered expression of MiR-221/-222 (increased miR-221/-222 expression ) and MiR-23b/-27b (down-regulated ) is associated with the development of human castration resistant prostate cancer. tissue_expression_down hsa-mir-23b Prostate Neoplasms 22127852 The altered expression of MiR-221/-222 (increased miR-221/-222 expression ) and MiR-23b/-27b (down-regulated ) is associated with the development of human castration resistant prostate cancer. tissue_expression_down hsa-mir-27b Prostate Neoplasms 22127852 The altered expression of MiR-221/-222 (increased miR-221/-222 expression ) and MiR-23b/-27b (down-regulated ) is associated with the development of human castration resistant prostate cancer. tissue_expression_down hsa-mir-107 Head And Neck Neoplasms 22158047 microRNA-107 functions as a candidate tumor-suppressor gene in head and neck squamous cell carcinoma by downregulation of protein kinase C tissue_expression_down hsa-mir-720 Rectal Neoplasms 22172905 "Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases." tissue_expression_down hsa-mir-122 "Carcinoma, Hepatocellular" 22174818 "Although miR-222, miR-223 or miR-21 were significantly up- or down-regulated between HCC patients and healthy controls, no significant difference was observed in the levels of these miRNAs between HBV patients without and with HCC. MiR-122 in serum was significantly higher in HCC patients than healthy controls (p<0.001). More importantly, it was found that the levels of miR-122 were significantly reduced in the post-operative serum samples when compared to the pre-operative samples. Although serum miR-122 was also elevated in HBV patients with HCC comparing with those without HCC, the difference was at the border line (p=0.043)." tissue_expression_down hsa-mir-21 "Carcinoma, Hepatocellular" 22174818 "Although miR-222, miR-223 or miR-21 were significantly up- or down-regulated between HCC patients and healthy controls, no significant difference was observed in the levels of these miRNAs between HBV patients without and with HCC. MiR-122 in serum was significantly higher in HCC patients than healthy controls (p<0.001). More importantly, it was found that the levels of miR-122 were significantly reduced in the post-operative serum samples when compared to the pre-operative samples. Although serum miR-122 was also elevated in HBV patients with HCC comparing with those without HCC, the difference was at the border line (p=0.043)." tissue_expression_down hsa-mir-222 "Carcinoma, Hepatocellular" 22174818 "Although miR-222, miR-223 or miR-21 were significantly up- or down-regulated between HCC patients and healthy controls, no significant difference was observed in the levels of these miRNAs between HBV patients without and with HCC. MiR-122 in serum was significantly higher in HCC patients than healthy controls (p<0.001). More importantly, it was found that the levels of miR-122 were significantly reduced in the post-operative serum samples when compared to the pre-operative samples. Although serum miR-122 was also elevated in HBV patients with HCC comparing with those without HCC, the difference was at the border line (p=0.043)." tissue_expression_down hsa-mir-223 "Carcinoma, Hepatocellular" 22174818 "Although miR-222, miR-223 or miR-21 were significantly up- or down-regulated between HCC patients and healthy controls, no significant difference was observed in the levels of these miRNAs between HBV patients without and with HCC. MiR-122 in serum was significantly higher in HCC patients than healthy controls (p<0.001). More importantly, it was found that the levels of miR-122 were significantly reduced in the post-operative serum samples when compared to the pre-operative samples. Although serum miR-122 was also elevated in HBV patients with HCC comparing with those without HCC, the difference was at the border line (p=0.043)." tissue_expression_down hsa-mir-1231 Colon Neoplasms 22180714 "Compared with expression in SW1116 cells, 35 miRNAs (including hsa-miR-192, hsa-miR-29b, hsa-miR-215, hsa-miR-194, hsa-miR-33a and hsa-miR-32) were upregulated more than 1.5-fold, and 11 miRNAs (including hsa-miR-93, hsa-miR-1231, hsa-miRPlus-F1080, hsa-miR-524-3p, hsa-miR-886-3p and hsa-miR-561) were downregulated in SW1116csc." tissue_expression_down hsa-mir-524 Colon Neoplasms 22180714 "Compared with expression in SW1116 cells, 35 miRNAs (including hsa-miR-192, hsa-miR-29b, hsa-miR-215, hsa-miR-194, hsa-miR-33a and hsa-miR-32) were upregulated more than 1.5-fold, and 11 miRNAs (including hsa-miR-93, hsa-miR-1231, hsa-miRPlus-F1080, hsa-miR-524-3p, hsa-miR-886-3p and hsa-miR-561) were downregulated in SW1116csc." tissue_expression_down hsa-mir-561 Colon Neoplasms 22180714 "Compared with expression in SW1116 cells, 35 miRNAs (including hsa-miR-192, hsa-miR-29b, hsa-miR-215, hsa-miR-194, hsa-miR-33a and hsa-miR-32) were upregulated more than 1.5-fold, and 11 miRNAs (including hsa-miR-93, hsa-miR-1231, hsa-miRPlus-F1080, hsa-miR-524-3p, hsa-miR-886-3p and hsa-miR-561) were downregulated in SW1116csc." tissue_expression_down hsa-mir-886 Colon Neoplasms 22180714 "Compared with expression in SW1116 cells, 35 miRNAs (including hsa-miR-192, hsa-miR-29b, hsa-miR-215, hsa-miR-194, hsa-miR-33a and hsa-miR-32) were upregulated more than 1.5-fold, and 11 miRNAs (including hsa-miR-93, hsa-miR-1231, hsa-miRPlus-F1080, hsa-miR-524-3p, hsa-miR-886-3p and hsa-miR-561) were downregulated in SW1116csc." tissue_expression_down hsa-mir-93 Colon Neoplasms 22180714 "Compared with expression in SW1116 cells, 35 miRNAs (including hsa-miR-192, hsa-miR-29b, hsa-miR-215, hsa-miR-194, hsa-miR-33a and hsa-miR-32) were upregulated more than 1.5-fold, and 11 miRNAs (including hsa-miR-93, hsa-miR-1231, hsa-miRPlus-F1080, hsa-miR-524-3p, hsa-miR-886-3p and hsa-miR-561) were downregulated in SW1116csc." tissue_expression_down hsa-mir-143 "Allergic Rhinitis,Perennial" 22185732 down-regulated tissue_expression_down hsa-mir-187 "Allergic Rhinitis,Perennial" 22185732 down-regulated tissue_expression_down hsa-mir-224 "Allergic Rhinitis,Perennial" 22185732 down-regulated tissue_expression_down hsa-mir-498 "Allergic Rhinitis,Perennial" 22185732 down-regulated tissue_expression_down hsa-mir-767 "Allergic Rhinitis,Perennial" 22185732 miR-767-5p: down-regulated tissue_expression_down hsa-mir-874 "Allergic Rhinitis,Perennial" 22185732 down-regulated tissue_expression_down hsa-mir-143 Urinary Bladder Cancer 22194833 mir-21 expression increased with worsening clinical diagnosis but that mir-143 was not correlated with histology. These observations were in stark contrast to previous reports involving cervical cancer cell lines in which mir-143 was consistently down-regulated but mir-21 largely unaffected. tissue_expression_down hsa-mir-192 Gastric Neoplasms 22205577 The down-regulation of miR-192 and -215 was demonstrated to be associated with increased tumor sizes and advanced Borrmann type tumors. tissue_expression_down hsa-mir-150 Acquired Immunodeficiency Syndrome 22205749 "we used microarray expression analysis to identify miRNAs miR-27b, miR-29b, miR-150, and miR-223 as being significantly downregulated upon CD4(+) T cell activation" tissue_expression_down hsa-mir-223 Acquired Immunodeficiency Syndrome 22205749 "we used microarray expression analysis to identify miRNAs miR-27b, miR-29b, miR-150, and miR-223 as being significantly downregulated upon CD4(+) T cell activation" tissue_expression_down hsa-mir-27b Acquired Immunodeficiency Syndrome 22205749 "we used microarray expression analysis to identify miRNAs miR-27b, miR-29b, miR-150, and miR-223 as being significantly downregulated upon CD4(+) T cell activation" tissue_expression_down hsa-mir-29b Acquired Immunodeficiency Syndrome 22205749 "we used microarray expression analysis to identify miRNAs miR-27b, miR-29b, miR-150, and miR-223 as being significantly downregulated upon CD4(+) T cell activation" tissue_expression_down hsa-mir-200a Diabetic Nephropathy 22211842 "TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated." tissue_expression_down hsa-mir-200b Diabetic Nephropathy 22211842 "TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated." tissue_expression_down hsa-mir-200c Diabetic Nephropathy 22211842 "TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated." tissue_expression_down hsa-mir-29a Diabetic Nephropathy 22211842 "TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated." tissue_expression_down hsa-mir-29b-1 Diabetic Nephropathy 22211842 "TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated." tissue_expression_down hsa-mir-29b-2 Diabetic Nephropathy 22211842 "TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated." tissue_expression_down hsa-mir-29c Diabetic Nephropathy 22211842 "TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated." tissue_expression_down hsa-mir-145 "Carcinoma, Hepatocellular" 22213236 down-regulated in HCC tissues. tissue_expression_down hsa-mir-146a "Carcinoma, Hepatocellular" 22213236 down-regulated in HCC tissues. tissue_expression_down hsa-mir-200c "Carcinoma, Hepatocellular" 22213236 down-regulated in HCC tissues. tissue_expression_down hsa-mir-223 "Carcinoma, Hepatocellular" 22213236 down-regulated in HCC tissues. tissue_expression_down hsa-mir-146a Pancreatic Neoplasms 22213426 "We found over-expression of miR-21, miR-221, miR-27a, miR-27b, and miR-155, and down-regulation of miR-216a,miR-216b, miR-217, and miR-146a expression in tumors derived from KC and KCI mouse model" tissue_expression_down hsa-mir-216a Pancreatic Neoplasms 22213426 "We found over-expression of miR-21, miR-221, miR-27a, miR-27b, and miR-155, and down-regulation of miR-216a,miR-216b, miR-217, and miR-146a expression in tumors derived from KC and KCI mouse model" tissue_expression_down hsa-mir-216b Pancreatic Neoplasms 22213426 "We found over-expression of miR-21, miR-221, miR-27a, miR-27b, and miR-155, and down-regulation of miR-216a,miR-216b, miR-217, and miR-146a expression in tumors derived from KC and KCI mouse model" tissue_expression_down hsa-mir-217 Pancreatic Neoplasms 22213426 "We found over-expression of miR-21, miR-221, miR-27a, miR-27b, and miR-155, and down-regulation of miR-216a,miR-216b, miR-217, and miR-146a expression in tumors derived from KC and KCI mouse model" tissue_expression_down hsa-mir-200c Melanoma 22223089 "miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors." tissue_expression_down hsa-mir-205 Melanoma 22223089 "miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors." tissue_expression_down hsa-mir-211 Melanoma 22223089 "miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors." tissue_expression_down hsa-mir-375 Head And Neck Neoplasms 22234174 Low-Level Expression of miR-375 Correlates with Poor Outcome and Metastasis While Altering the Invasive Properties of Head and Neck Squamous Cell Carcinomas. tissue_expression_down hsa-mir-203 Melanoma 22235882 "A decreased expression of miR-203 was significantly associated with a shorter survival time. Also, miR-203 and -205 were markedly down-regulated in canine and human MM cell lines tested." tissue_expression_down hsa-mir-205 Melanoma 22235882 "A decreased expression of miR-203 was significantly associated with a shorter survival time. Also, miR-203 and -205 were markedly down-regulated in canine and human MM cell lines tested." tissue_expression_down hsa-let-7e Colorectal Carcinoma 22241525 "Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143)" tissue_expression_down hsa-mir-122 Colorectal Carcinoma 22241525 "Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143)" tissue_expression_down hsa-mir-143 Colorectal Carcinoma 22241525 "Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143)" tissue_expression_down hsa-mir-146b Colorectal Carcinoma 22241525 "Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143)" tissue_expression_down hsa-mir-17 Colorectal Carcinoma 22241525 "Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143)" tissue_expression_down hsa-mir-181a-2 Colorectal Carcinoma 22241525 "Six miRNAs were up-regulated from non-neoplastic tissue to dysplasia, but down-regulated from dysplasia to cancer (miR-122, miR-181a, miR-146b-5p, let-7e, miR-17, miR-143)" tissue_expression_down hsa-mir-146b Neuroblastoma 22244746 under-expressed in mature neuron. tissue_expression_down hsa-mir-152 Neuroblastoma 22244746 under-expressed in mature neuron. tissue_expression_down hsa-mir-339 Neuroblastoma 22244746 miR-339-5p: under-expressed in mature neuron. tissue_expression_down hsa-mir-370 Neuroblastoma 22244746 under-expressed in neuroblastoma. tissue_expression_down hsa-mir-9-1 Neuroblastoma 22244746 under-expressed in neuroblastoma. tissue_expression_down hsa-mir-9-2 Neuroblastoma 22244746 under-expressed in neuroblastoma. tissue_expression_down hsa-mir-9-3 Neuroblastoma 22244746 under-expressed in neuroblastoma. tissue_expression_down hsa-mir-34b Parkinson Disease 22245218 "miR-133b is deficient in the PD midbrain as well as in mouse models, and miR-34b/34c are decreased in several affected brain regions in PD and incidental Lewy body disease." tissue_expression_down hsa-mir-34c Parkinson Disease 22245218 "miR-133b is deficient in the PD midbrain as well as in mouse models, and miR-34b/34c are decreased in several affected brain regions in PD and incidental Lewy body disease." tissue_expression_down hsa-mir-100 Ovarian Neoplasms 22246341 "The level of miR-100 was significantly lower in EOC (epithelial ovarian cancer) tissues compared to adjacent normal tissues. Low miR-100 expression was found to be closely correlated with advanced FIGO stage, higher serum CA125 expression level and lymph node involvement." tissue_expression_down hsa-mir-143 Colorectal Carcinoma 22273643 Down-regulation of fecal miR-143 and miR-145 are potential markers for colorectal cancer. tissue_expression_down hsa-mir-145 Colorectal Carcinoma 22273643 Down-regulation of fecal miR-143 and miR-145 are potential markers for colorectal cancer. tissue_expression_down hsa-let-7c "Carcinoma, Hepatocellular" 22289550 Levels of let-7c miRNA were significantly lower in HCC tissues than in corresponding normal adjacent tumour tissues and there was a correlation between the downregulation of let-7c and poor tissue differentiation in HCC. tissue_expression_down hsa-mir-134 Lung Neoplasms 22306127 miR-27b and miR-134 levels were significantly lower in the tumors than normal tissue. tissue_expression_down hsa-mir-27b Lung Neoplasms 22306127 miR-27b and miR-134 levels were significantly lower in the tumors than normal tissue. tissue_expression_down hsa-mir-125a Lymphoma 22307176 significantly underexpressed in SMZL (splenic marginal zone lymphoma). tissue_expression_down hsa-mir-126 Lymphoma 22307176 significantly underexpressed in SMZL (splenic marginal zone lymphoma). tissue_expression_down hsa-mir-139 Lymphoma 22307176 significantly underexpressed in SMZL (splenic marginal zone lymphoma). tissue_expression_down hsa-mir-146a Lymphoma 22307176 significantly overexpressed in SMZL (splenic marginal zone lymphoma). tissue_expression_down hsa-mir-155 Lymphoma 22307176 significantly overexpressed in SMZL (splenic marginal zone lymphoma). tissue_expression_down hsa-mir-21 Lymphoma 22307176 significantly overexpressed in SMZL (splenic marginal zone lymphoma). tissue_expression_down hsa-mir-345 Lymphoma 22307176 significantly underexpressed in SMZL (splenic marginal zone lymphoma). tissue_expression_down hsa-mir-122 "Carcinoma, Hepatocellular" 22312705 MiR-122 increases sensitivity of drug-resistant BEL-7402/5-FU cells to 5-fluorouracil via down-regulation of bcl-2 family proteins. tissue_expression_down hsa-mir-1322 Esophageal Neoplasms 22315007 "miR-1322 could significantly down-regulate the ECRG2 with TCA3 allele (P<0.01), but it could not down-regulate the ECRG2 with TCA4 allele significantly (P>0.05). MicroRNA-1322 regulates ECRG2 allele specifically and acts as a potential biomarker in patients with esophageal squamous cell carcinoma." tissue_expression_down hsa-mir-132 Schizophrenia 22315408 MicroRNA-132 downregulation in schizophrenia has implications for both neurodevelopment and adult brain function. tissue_expression_down hsa-let-7d Breast Neoplasms 22315424 "let-7d, miR-210, and -221 were down-regulated in the in situ and up-regulated in the invasive transition, thus featuring an expression reversal along the cancer progression path." tissue_expression_down hsa-mir-210 Breast Neoplasms 22315424 "let-7d, miR-210, and -221 were down-regulated in the in situ and up-regulated in the invasive transition, thus featuring an expression reversal along the cancer progression path." tissue_expression_down hsa-mir-221 Breast Neoplasms 22315424 "let-7d, miR-210, and -221 were down-regulated in the in situ and up-regulated in the invasive transition, thus featuring an expression reversal along the cancer progression path." tissue_expression_down hsa-mir-223 "Leukemia, Lymphocytic, Chronic, B-Cell" 22321781 The down-regulation of microRNA-223 was associated with disease aggressiveness in CLL. tissue_expression_down hsa-mir-193a Lung Neoplasms 22325218 mir-33a was down-regulated by 92.8% and mir-193a-3p by 86.5% in epithelial-mesenchymal transition (EMT) on the expression of microRNAs (miRNAs) in lung cancer A549 cells. tissue_expression_down hsa-mir-33a Lung Neoplasms 22325218 mir-33a was down-regulated by 92.8% and mir-193a-3p by 86.5% in epithelial-mesenchymal transition (EMT) on the expression of microRNAs (miRNAs) in lung cancer A549 cells. tissue_expression_down hsa-mir-155 Inflammation 22326887 Glucocorticoids inhibit lipopolysaccharide-mediated inflammatory response by downregulating microRNA-155 tissue_expression_down hsa-mir-17 Urinary Bladder Cancer 22334592 The anticancer activity of CSL in 253JB-V cells is due to induction of ROS and ROS-mediated induction of Sp repressors (ZBTB4/ZBTB10) through downregulation of miR-27a and miR-20a/17-5p. tissue_expression_down hsa-mir-20a Urinary Bladder Cancer 22334592 The anticancer activity of CSL in 253JB-V cells is due to induction of ROS and ROS-mediated induction of Sp repressors (ZBTB4/ZBTB10) through downregulation of miR-27a and miR-20a/17-5p. tissue_expression_down hsa-mir-27a Urinary Bladder Cancer 22334592 The anticancer activity of CSL in 253JB-V cells is due to induction of ROS and ROS-mediated induction of Sp repressors (ZBTB4/ZBTB10) through downregulation of miR-27a and miR-20a/17-5p. tissue_expression_down hsa-mir-142 Osteosarcoma 22350417 reduced expression tissue_expression_down hsa-mir-16-1 Osteosarcoma 22350417 reduced expression tissue_expression_down hsa-mir-16-2 Osteosarcoma 22350417 reduced expression tissue_expression_down hsa-mir-29b-1 Osteosarcoma 22350417 reduced expression tissue_expression_down hsa-mir-29b-2 Osteosarcoma 22350417 reduced expression tissue_expression_down hsa-mir-203 Burns 22360957 miR-203 was down-regulated in denatured dermis compared with those in normal skin. tissue_expression_down hsa-mir-21 Esophageal Neoplasms 22363450 "Curcumin treatment down-regulate the expressions of Notch-1 specific microRNAs miR-21 and miR-34a, and upregulated tumor suppressor let-7a miRNA." tissue_expression_down hsa-mir-34a Esophageal Neoplasms 22363450 "Curcumin treatment down-regulate the expressions of Notch-1 specific microRNAs miR-21 and miR-34a, and upregulated tumor suppressor let-7a miRNA." tissue_expression_down hsa-mir-145 Gastric Neoplasms 22370644 "The authors demonstrate a stepwise downregulation of miR-145 level in nontumorous gastric mucosa, primary gastric cancers and their secondary metastases.N-cadherin (CDH2) was proved to be a direct target of miR-145" tissue_expression_down hsa-mir-155 Myelodysplastic Syndromes 22371183 "Real-time PCR approach confirmed that mir-155, miR-181a and miR-222 were down-expressed in mesenchymal stromal cells from myelodysplastic syndrome patients." tissue_expression_down hsa-mir-181a-1 Myelodysplastic Syndromes 22371183 "Real-time PCR approach confirmed that mir-155, miR-181a and miR-222 were down-expressed in mesenchymal stromal cells from myelodysplastic syndrome patients." tissue_expression_down hsa-mir-181a-2 Myelodysplastic Syndromes 22371183 "Real-time PCR approach confirmed that mir-155, miR-181a and miR-222 were down-expressed in mesenchymal stromal cells from myelodysplastic syndrome patients." tissue_expression_down hsa-mir-222 Myelodysplastic Syndromes 22371183 "Real-time PCR approach confirmed that mir-155, miR-181a and miR-222 were down-expressed in mesenchymal stromal cells from myelodysplastic syndrome patients." tissue_expression_down hsa-let-7a-1 Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_down hsa-let-7a-2 Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_down hsa-let-7a-3 Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_down hsa-mir-375 Colorectal Carcinoma 22377847 miR-375 expression was frequently downregulated in the colorectal cancer tissues compared to the non-tumor counterparts tissue_expression_down hsa-mir-183 "Carcinoma, Basal Cell" 22384406 The expression level of miR-183 was consistently lower in infiltrative than nodular tumors and could be one element underlying the difference in invasiveness. tissue_expression_down hsa-mir-192 Urinary Bladder Cancer 22386240 "Compared with controls, the patients with bladder cancer had a lower expression of the miR-200 family, miR-192, and miR-155 in the urinary sediment; lower expression of miR-192; and higher expression of miR-155 in the urinary supernatant." tissue_expression_down hsa-mir-200a Urinary Bladder Cancer 22386240 "Compared with controls, the patients with bladder cancer had a lower expression of the miR-200 family, miR-192, and miR-155 in the urinary sediment; lower expression of miR-192; and higher expression of miR-155 in the urinary supernatant." tissue_expression_down hsa-mir-200b Urinary Bladder Cancer 22386240 "Compared with controls, the patients with bladder cancer had a lower expression of the miR-200 family, miR-192, and miR-155 in the urinary sediment; lower expression of miR-192; and higher expression of miR-155 in the urinary supernatant." tissue_expression_down hsa-mir-200c Urinary Bladder Cancer 22386240 "Compared with controls, the patients with bladder cancer had a lower expression of the miR-200 family, miR-192, and miR-155 in the urinary sediment; lower expression of miR-192; and higher expression of miR-155 in the urinary supernatant." tissue_expression_down hsa-mir-130a Prostate Neoplasms 22391564 "MiR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma." tissue_expression_down hsa-mir-203 Prostate Neoplasms 22391564 "MiR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma." tissue_expression_down hsa-mir-205 Prostate Neoplasms 22391564 "MiR-130a, miR-203 and miR-205 jointly repress key oncogenic pathways and are downregulated in prostate carcinoma." tissue_expression_down hsa-mir-100 Bladder Neoplasms 22393979 Differential miRNA expression profiles in bladder urothelial carcinomas identified miR-100 down-regulation and miR-708 up-regulation among the most common alterations tissue_expression_down hsa-mir-129-1 "Scleroderma, Systemic" 22403442 "IL-17A signaling, not IL-17F, has an antifibrogenic effect via the upregulation of miR-129-5p and the downregulation of connective tissue growth factor and §Ø©ã(I) collagen." tissue_expression_down hsa-mir-129-2 "Scleroderma, Systemic" 22403442 "IL-17A signaling, not IL-17F, has an antifibrogenic effect via the upregulation of miR-129-5p and the downregulation of connective tissue growth factor and §Ø©ã(I) collagen." tissue_expression_down hsa-let-7a-1 Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_down hsa-let-7a-2 Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_down hsa-let-7a-3 Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_down hsa-let-7b Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_down hsa-let-7c Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_down hsa-let-7d Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_down hsa-let-7e Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_down hsa-let-7f-1 Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_down hsa-let-7f-2 Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_down hsa-mir-1915 Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_down hsa-mir-27b Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_down hsa-mir-137 Glioblastoma 22406049 miR-137 is frequently down-regulated in glioblastoma and is a negative regulator of Cox-2. tissue_expression_down hsa-mir-217 Human Immunodeficiency Virus Infection 22406815 MiR-217 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation by down-regulation of SIRT1. tissue_expression_down hsa-let-7f-2 Breast Neoplasms 22407818 "Aromatase inhibitor treatment of breast cancer cells increases the expression of let-7f, a microRNA targeting CYP19A1." tissue_expression_down hsa-mir-92a-1 Prostate Neoplasms 22412975 "Isoflavone and BR-DIM down-regulated the expression of miR-92a, which is known to be associated with RANKL signaling, EMT and cancer progression." tissue_expression_down hsa-mir-92a-2 Prostate Neoplasms 22412975 "Isoflavone and BR-DIM down-regulated the expression of miR-92a, which is known to be associated with RANKL signaling, EMT and cancer progression." tissue_expression_down hsa-mir-100 Head And Neck Neoplasms 22425712 down-regulation tissue_expression_down hsa-mir-375 Head And Neck Neoplasms 22425712 down-regulation tissue_expression_down hsa-mir-99a Head And Neck Neoplasms 22425712 down-regulation tissue_expression_down hsa-mir-155 Gastric Neoplasms 22426647 microRNA-155 is downregulated in gastric cancer cells and involved in cell metastasis. tissue_expression_down hsa-let-7c "Carcinoma, Lung, Small-Cell" 22438992 "Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix." tissue_expression_down hsa-mir-100 "Carcinoma, Lung, Small-Cell" 22438992 "Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix." tissue_expression_down hsa-mir-125b-1 "Carcinoma, Lung, Small-Cell" 22438992 "Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix." tissue_expression_down hsa-mir-125b-2 "Carcinoma, Lung, Small-Cell" 22438992 "Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix." tissue_expression_down hsa-mir-143 "Carcinoma, Lung, Small-Cell" 22438992 "Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix." tissue_expression_down hsa-mir-145 "Carcinoma, Lung, Small-Cell" 22438992 "Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix." tissue_expression_down hsa-mir-199a-1 "Carcinoma, Lung, Small-Cell" 22438992 "Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix." tissue_expression_down hsa-mir-199a-2 "Carcinoma, Lung, Small-Cell" 22438992 "Downregulation of Six MicroRNAs (has-let-7c, has-miR-100, has-miR-125b, has-miR-143, has-miR-145 and has-miR-199a-5p) Is Associated with Advanced Stage, Lymph Node Metastasis and Poor Prognosis in Small Cell Carcinoma of the Cervix." tissue_expression_down hsa-mir-140 Ovarian Neoplasms 22452920 "The expression level of RAD51AP1 was found to be strongly anti-correlated with the expression of hsa-miR-140-3p, which was significantly down-regulated in the tumour samples." tissue_expression_down hsa-mir-15a Multiple Sclerosis 22463747 miR-15a and 16-1 are downregulated in CD4(+) T cells of multiple sclerosis relapsing patients. tissue_expression_down hsa-mir-16-1 Multiple Sclerosis 22463747 miR-15a and 16-1 are downregulated in CD4(+) T cells of multiple sclerosis relapsing patients. tissue_expression_down hsa-mir-215 Colorectal Carcinoma 22469014 "MiR-215, miR-375, miR-378 and miR-422a were significantly decreased, whereas miR-135b was increased in CRC tumor tissues. Levels of miR-215 and miR-422a correlated with clinical stage." tissue_expression_down hsa-mir-378a Colorectal Carcinoma 22469014 "MiR-215, miR-375, miR-378 and miR-422a were significantly decreased, whereas miR-135b was increased in CRC tumor tissues. Levels of miR-215 and miR-422a correlated with clinical stage." tissue_expression_down hsa-mir-422a Colorectal Carcinoma 22469014 "MiR-215, miR-375, miR-378 and miR-422a were significantly decreased, whereas miR-135b was increased in CRC tumor tissues. Levels of miR-215 and miR-422a correlated with clinical stage." tissue_expression_down hsa-mir-125b-1 Prolactinoma 22490835 down-regulated tissue_expression_down hsa-mir-125b-2 Prolactinoma 22490835 down-regulated tissue_expression_down hsa-mir-130a Prolactinoma 22490835 down-regulated tissue_expression_down hsa-mir-199b Prolactinoma 22490835 miR-199b-3p: down-regulated tissue_expression_down hsa-mir-200b Prolactinoma 22490835 down-regulated tissue_expression_down hsa-mir-22 Colorectal Carcinoma 22492279 "The relative expression levels of miR-22 were significantly lower in colorectal cancer tissues than those in the normal adjacent mucosa, and low expression of miR-22 correlated with liver metastasis. Kaplan-Meier analysis indicated that patients with reduced miR-22 had a poor overall survival." tissue_expression_down hsa-mir-10b "Carcinoma, Renal Cell" 22492545 "Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse." tissue_expression_down hsa-mir-126 "Carcinoma, Renal Cell" 22492545 "Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse." tissue_expression_down hsa-mir-143 "Carcinoma, Renal Cell" 22492545 "Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse." tissue_expression_down hsa-mir-145 "Carcinoma, Renal Cell" 22492545 "Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse." tissue_expression_down hsa-mir-195 "Carcinoma, Renal Cell" 22492545 "Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse." tissue_expression_down hsa-mir-26a-1 "Carcinoma, Renal Cell" 22492545 "Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse." tissue_expression_down hsa-mir-26a-2 "Carcinoma, Renal Cell" 22492545 "Expression levels of miR-143, miR-26a, miR-145, miR-10b, miR-195, and miR-126 are lower in the tumors of RCC patients who developed tumor relapse." tissue_expression_down hsa-mir-106b Neuroblastoma 22498172 "Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells)" tissue_expression_down hsa-mir-92a-1 Neuroblastoma 22498172 "Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells)" tissue_expression_down hsa-mir-92a-2 Neuroblastoma 22498172 "Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells)" tissue_expression_down hsa-mir-92b Neuroblastoma 22498172 "Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells)" tissue_expression_down hsa-mir-93 Neuroblastoma 22498172 "Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells)" tissue_expression_down hsa-mir-155 "Leukemia, Myeloid, Chronic" 22511990 "Downregulation of mir-31, mir-155, and mir-564 in chronic myeloid leukemia cells." tissue_expression_down hsa-mir-31 "Leukemia, Myeloid, Chronic" 22511990 "Downregulation of mir-31, mir-155, and mir-564 in chronic myeloid leukemia cells." tissue_expression_down hsa-mir-564 "Leukemia, Myeloid, Chronic" 22511990 "Downregulation of mir-31, mir-155, and mir-564 in chronic myeloid leukemia cells." tissue_expression_down hsa-mir-126 Breast Neoplasms 22524830 "down regulation in mir-17p, mir-126, mir-335, mir-30b" tissue_expression_down hsa-mir-17 Breast Neoplasms 22524830 "down regulation in mir-17p, mir-126, mir-335, mir-30b" tissue_expression_down hsa-mir-30b Breast Neoplasms 22524830 "down regulation in mir-17p, mir-126, mir-335, mir-30b" tissue_expression_down hsa-mir-335 Breast Neoplasms 22524830 "down regulation in mir-17p, mir-126, mir-335, mir-30b" tissue_expression_down hsa-mir-675 Osteoarthritis 22527881 "Proinflammatory cytokines IL-1beta and TNF-alpha downregulated COL2A1, H19, and miR-675 significantly without close statistical correlation." tissue_expression_down hsa-mir-133b Prostate Neoplasms 22532850 "Expression of miR-133b in tumor specimens of prostate cancer patients was significantly downregulated in 75% of the cases, when compared with matched healthy tissue." tissue_expression_down hsa-mir-181a-2 Coronary Artery Disease 22535975 Decreased miR-181a Expression in Monocytes of Obese Patients Is Associated with the Occurrence of Metabolic Syndrome and Coronary Artery Disease. tissue_expression_down hsa-mir-129-1 "Carcinoma, Hepatocellular" 22536440 "VCP/p97, down-regulated by microRNA-129-5p, could regulate the progression of hepatocellular carcinoma." tissue_expression_down hsa-mir-129-2 "Carcinoma, Hepatocellular" 22536440 "VCP/p97, down-regulated by microRNA-129-5p, could regulate the progression of hepatocellular carcinoma." tissue_expression_down hsa-mir-139 "Carcinoma, Basal Cell" 22540308 miR-139-5p is downregulated in the tumor center tissue_expression_down hsa-mir-140 "Carcinoma, Basal Cell" 22540308 miR-140-3p is downregulated in the tumor center tissue_expression_down hsa-mir-145 "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-2861 "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-29c "Carcinoma, Basal Cell" 22540308 miR-29c and miR-29c* are downregulated in the tumor center tissue_expression_down hsa-mir-3196 "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-378a "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-378b "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-378c "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-378d-1 "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-378d-2 "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-378e "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-378f "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-378g "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-378h "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-378i "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-572 "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-638 "Carcinoma, Basal Cell" 22540308 downregulated in the tumor center tissue_expression_down hsa-mir-193b Endometrial Neoplasms 22543862 Decreased expression after Progesterone Treatment. tissue_expression_down hsa-mir-29c Endometrial Neoplasms 22543862 Decreased expression after Progesterone Treatment. tissue_expression_down hsa-mir-633 Endometrial Neoplasms 22543862 Decreased expression after Progesterone Treatment. tissue_expression_down hsa-mir-138-1 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. tissue_expression_down hsa-mir-138-2 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. tissue_expression_down hsa-mir-15a Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. tissue_expression_down hsa-mir-16-1 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. tissue_expression_down hsa-mir-16-2 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. tissue_expression_down hsa-mir-181a-1 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. tissue_expression_down hsa-mir-181a-2 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. tissue_expression_down hsa-mir-191 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. tissue_expression_down hsa-mir-933 Melanoma 22551973 The downregulation of this miRNA was associated with selective genomic loss in SSM cell lines and primary tumors. tissue_expression_down hsa-mir-155 Asthma 22558995 The decreased expression level of miR-155 is correlated to asthma disease severity. tissue_expression_down hsa-mir-16-1 Breast Neoplasms 22583478 Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development. tissue_expression_down hsa-mir-125b-1 Laryngeal Neoplasms 22605671 Downregulation tissue_expression_down hsa-mir-125b-2 Laryngeal Neoplasms 22605671 Downregulation tissue_expression_down hsa-mir-145 Laryngeal Neoplasms 22605671 Downregulation tissue_expression_down hsa-mir-214 "Carcinoma, Hepatocellular" 22613005 MicroRNA-214 downregulation contributes to tumor angiogenesis by inducing secretion of the hepatoma-derived growth factor in human hepatoma. tissue_expression_down hsa-let-7e "Carcinoma, Lung, Non-Small-Cell" 22618509 "We showed that, compared to adjacent non-neoplastic lung tissues, the expressions of miR-125a-5p and let-7e were decreased in AD and SCC samples" tissue_expression_down hsa-mir-125a "Carcinoma, Lung, Non-Small-Cell" 22618509 "We showed that, compared to adjacent non-neoplastic lung tissues, the expressions of miR-125a-5p and let-7e were decreased in AD and SCC samples" tissue_expression_down hsa-mir-34a Breast Neoplasms 22623155 MiR-34a inhibits proliferation and migration of breast cancer through down-regulation of Bcl-2 and SIRT1. tissue_expression_down hsa-mir-34a "Squamous Cell Carcinoma, Sinonasal" 22624980 miR-34a is downregulated in cis-diamminedichloroplatinum treated sinonasal squamous cell carcinoma patients with poor prognosis. tissue_expression_down hsa-mir-1202 Ovarian Neoplasms 22643117 "We found 37 differentially expressed miRNAs in the CD133(+) spheroid-forming subpopulation of OVCAR3 cells, 34 of which were significantly up-regulated, including miR-205, miR-146a, miR-200a, miR-200b, and miR-3, and 3 of which were significantly down-regulated, including miR-1202 and miR-1181." tissue_expression_down hsa-mir-1281 Ovarian Neoplasms 22643117 "We found 37 differentially expressed miRNAs in the CD133(+) spheroid-forming subpopulation of OVCAR3 cells, 34 of which were significantly up-regulated, including miR-205, miR-146a, miR-200a, miR-200b, and miR-3, and 3 of which were significantly down-regulated, including miR-1202 and miR-1181." tissue_expression_down hsa-mir-126 Lung Neoplasms 22672859 "Four up-regulated microRNAs (miR-210, miR-21, miR-31 and miR-182) and two down-regulated mcroiRNAs (miR-126 and miR-145) were consistently reported both in squamous carcinoma and adenocarcinoma-based subgroup analysis" tissue_expression_down hsa-mir-145 Lung Neoplasms 22672859 "Four up-regulated microRNAs (miR-210, miR-21, miR-31 and miR-182) and two down-regulated mcroiRNAs (miR-126 and miR-145) were consistently reported both in squamous carcinoma and adenocarcinoma-based subgroup analysis" tissue_expression_down hsa-mir-133a-1 Astrocytoma 22674182 Significantly decreased in grades II-IV patients. tissue_expression_down hsa-mir-133a-2 Astrocytoma 22674182 Significantly decreased in grades II-IV patients. tissue_expression_down hsa-mir-150 Astrocytoma 22674182 miR-150*:Significantly decreased in grades II-IV patients. tissue_expression_down hsa-mir-15b Astrocytoma 22674182 miR-15b*: Significantly decreased in grades II-IV patients. tissue_expression_down hsa-mir-197 Astrocytoma 22674182 Significantly decreased in grades II-IV patients. tissue_expression_down hsa-mir-23a Astrocytoma 22674182 Significantly decreased in grades II-IV patients. tissue_expression_down hsa-mir-497 Astrocytoma 22674182 Significantly decreased in grades II-IV patients. tissue_expression_down hsa-mir-548b Astrocytoma 22674182 miR-548b-5p: Significantly decreased in grades II-IV patients. tissue_expression_down hsa-mir-219 Meningioma 22674195 Downregulation of miR-29c-3p and miR-219-5p were found to be associated with advanced clinical stages of meningioma. Kaplan-Meier analysis showed that high expression of miR-190a and low expression of miR-29c-3p and miR-219-5p correlated significantly with higher recurrence rates in meningioma patients. tissue_expression_down hsa-mir-29c Meningioma 22674195 Downregulation of miR-29c-3p and miR-219-5p were found to be associated with advanced clinical stages of meningioma. Kaplan-Meier analysis showed that high expression of miR-190a and low expression of miR-29c-3p and miR-219-5p correlated significantly with higher recurrence rates in meningioma patients. tissue_expression_down hsa-mir-182 "Carcinoma, Hepatocellular" 22681717 MicroRNA-182 downregulates metastasis suppressor 1 and contributes to metastasis of hepatocellular carcinoma. tissue_expression_down hsa-mir-100 Chronic Obstructive Pulmonary Disease 22686440 "There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls." tissue_expression_down hsa-mir-20a Chronic Obstructive Pulmonary Disease 22686440 "There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls." tissue_expression_down hsa-mir-28 Chronic Obstructive Pulmonary Disease 22686440 "There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls." tissue_expression_down hsa-mir-34c Chronic Obstructive Pulmonary Disease 22686440 "There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls." tissue_expression_down hsa-mir-7-1 Chronic Obstructive Pulmonary Disease 22686440 "There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls." tissue_expression_down hsa-mir-7-2 Chronic Obstructive Pulmonary Disease 22686440 "There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls." tissue_expression_down hsa-mir-7-3 Chronic Obstructive Pulmonary Disease 22686440 "There was down-regulation of miR-20a, miR-28-3p, miR-34c-5p, and miR-100, and up-regulation of miR-7, compared with the controls." tissue_expression_down hsa-mir-10b Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-126 Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-145 Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-19a Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-221 Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-296 Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-378a Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-378b Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-378c Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-378d-1 Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-378d-2 Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-378e Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-378f Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-378g Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-378h Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-378i Urinary Bladder Cancer 22704449 "miR-10b, 19a, 126, 145, 221, 296-5p and 378 were significantly down-regulated in bladder cancer compared to adjacent normal urothelium." tissue_expression_down hsa-mir-325 Preeclampsia 22710575 The expression of hsa-miR-325 was downregulated in the case of PE. Changes in hsa-miR-325 expression in the case of pregnancy-related hypertensive disorders might affect the oxidative stress pathways and heat-shock protein production. tissue_expression_down hsa-mir-199a-1 "Carcinoma, Hepatocellular" 22713463 Cisplatin-induced downregulation of miR-199a-5p increases drug resistance by activating autophagy in HCC cell. tissue_expression_down hsa-mir-199a-2 "Carcinoma, Hepatocellular" 22713463 Cisplatin-induced downregulation of miR-199a-5p increases drug resistance by activating autophagy in HCC cell. tissue_expression_down hsa-mir-106a Prostate Neoplasms 22719071 downregulated in prostate cancer stem/progenitor cell. tissue_expression_down hsa-mir-141 Prostate Neoplasms 22719071 downregulated in prostate cancer stem/progenitor cell. tissue_expression_down hsa-mir-34a Prostate Neoplasms 22719071 downregulated in prostate cancer stem/progenitor cell. tissue_expression_down hsa-mir-125b-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 22723551 The downregulation of miR-125b in chronic lymphocytic leukemias leads to metabolic adaptation of cells to a transformed state. tissue_expression_down hsa-mir-125b-2 "Leukemia, Lymphocytic, Chronic, B-Cell" 22723551 The downregulation of miR-125b in chronic lymphocytic leukemias leads to metabolic adaptation of cells to a transformed state. tissue_expression_down hsa-mir-31 Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_down hsa-mir-99a "Carcinoma, Oral" 22751686 Downregulation of microRNA 99a in oral squamous cell carcinomas contributes to the growth and survival of oral cancer cells. tissue_expression_down hsa-mir-650 "Carcinoma, Hepatocellular" 22767438 Upregulation of miR-650 is correlated with down-regulation of ING4 and progression of hepatocellular carcinoma. tissue_expression_down hsa-mir-125b-1 Myotonic Muscular Dystrophy 22768114 miR-125b-5p: decreased levels compared to controls tissue_expression_down hsa-mir-193a Myotonic Muscular Dystrophy 22768114 miR-193a-3p: decreased levels compared to controls tissue_expression_down hsa-mir-193b Myotonic Muscular Dystrophy 22768114 miR-193b-3p: decreased levels compared to controls tissue_expression_down hsa-mir-378a Myotonic Muscular Dystrophy 22768114 miR-378a-3p: decreased levels compared to controls tissue_expression_down hsa-let-7e Interstitial Lung Disease 22782705 downregulated tissue_expression_down hsa-mir-142 Interstitial Lung Disease 22782705 miR-142-5p: downregulated tissue_expression_down hsa-mir-19a Interstitial Lung Disease 22782705 downregulated tissue_expression_down hsa-mir-195 Breast Neoplasms 22800791 "The levels of miR-195 in the breast cancer with histological high grade, tumor size of T3-4, lymph nodal involvement or vessel invasion were significantly down-regulated, compared with those of patients with histological low grade (Z = -2.271, P = 0.023), tumor size of T1-2 (Z = -2.687, P = 0.007), no lymph node metastasis (Z = -1.967, P = 0.049) and vessel invasion (Z = -2.432, P = 0.015)." tissue_expression_down hsa-mir-26b Head And Neck Neoplasms 22811001 "In addition, the expression levels of miR-21 and miR-26b were both reduced in post-operative HNSCC patients with good prognosis." tissue_expression_down hsa-mir-22 Prostate Neoplasms 22815235 "We previously detected several miRNAs, for example, miR-24 and miR-22, as significantly downregulated in Pca" tissue_expression_down hsa-mir-24 Prostate Neoplasms 22815235 "We previously detected several miRNAs, for example, miR-24 and miR-22, as significantly downregulated in Pca" tissue_expression_down hsa-mir-155 Behcet Disease 22815348 Decreased microRNA-155 Expression in Ocular Behcet's Disease but Not in Vogt Koyanagi Harada Syndrome. tissue_expression_down hsa-let-7i Pancreatic Neoplasms 22820191 "Knockdown of Dicer 1 expression in BxPC-3 and Panc-1 cells resulted in significant increases in KRAS, p53, PTEN, and Dnmts protein levels and significant decreases in miR-22, miR-143, let-7i, and miR-29b expression." tissue_expression_down hsa-mir-143 Pancreatic Neoplasms 22820191 "Knockdown of Dicer 1 expression in BxPC-3 and Panc-1 cells resulted in significant increases in KRAS, p53, PTEN, and Dnmts protein levels and significant decreases in miR-22, miR-143, let-7i, and miR-29b expression." tissue_expression_down hsa-mir-22 Pancreatic Neoplasms 22820191 "Knockdown of Dicer 1 expression in BxPC-3 and Panc-1 cells resulted in significant increases in KRAS, p53, PTEN, and Dnmts protein levels and significant decreases in miR-22, miR-143, let-7i, and miR-29b expression." tissue_expression_down hsa-mir-29b Pancreatic Neoplasms 22820191 "Knockdown of Dicer 1 expression in BxPC-3 and Panc-1 cells resulted in significant increases in KRAS, p53, PTEN, and Dnmts protein levels and significant decreases in miR-22, miR-143, let-7i, and miR-29b expression." tissue_expression_down hsa-mir-200b Pancreatic Neoplasms 22821831 "Furthermore, MIF-overexpression significantly increased ZEB1/2 and decreased miR-200b expression, while shRNA-mediated inhibition of MIF increased E-cadherin and miR-200b expression, and reduced the expression of ZEB1/2 in Panc1 cells." tissue_expression_down hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 22835608 Low miR-145 and high miR-367 are associated with unfavorable prognosis in resected NSCLC. tissue_expression_down hsa-mir-124-1 Sepsis 22846781 Corticosteroid resistance in sepsis is influenced by microRNA-124-induced downregulation of glucocorticoid receptor-alpha tissue_expression_down hsa-mir-124-2 Sepsis 22846781 Corticosteroid resistance in sepsis is influenced by microRNA-124-induced downregulation of glucocorticoid receptor-alpha tissue_expression_down hsa-mir-195 Melanoma 22847610 miR-195-mediated downregulation of WEE1 in metastatic lesions may help to overcome cell cycle arrest under stress conditions in the local tissue microenvironment to allow unrestricted growth of tumour cells. tissue_expression_down hsa-let-7b Esophageal Neoplasms 22847808 "Low expression of let-7b and let-7c in before-treatment biopsies from 74 patients of the training set correlated significantly with poor response to chemotherapy, both clinically and histopathologically." tissue_expression_down hsa-let-7c Esophageal Neoplasms 22847808 "Low expression of let-7b and let-7c in before-treatment biopsies from 74 patients of the training set correlated significantly with poor response to chemotherapy, both clinically and histopathologically." tissue_expression_down hsa-mir-122 Pancreatic Neoplasms 22850622 "miR-21, miR-155, miR-210, miR-221, and miR-222, were overexpressed in diseased tissues than in the control samples, whereas miR-31, miR-122, miR-145, and miR-146a were underexpressed." tissue_expression_down hsa-mir-145 Pancreatic Neoplasms 22850622 "miR-21, miR-155, miR-210, miR-221, and miR-222, were overexpressed in diseased tissues than in the control samples, whereas miR-31, miR-122, miR-145, and miR-146a were underexpressed." tissue_expression_down hsa-mir-146a Pancreatic Neoplasms 22850622 "miR-21, miR-155, miR-210, miR-221, and miR-222, were overexpressed in diseased tissues than in the control samples, whereas miR-31, miR-122, miR-145, and miR-146a were underexpressed." tissue_expression_down hsa-mir-31 Pancreatic Neoplasms 22850622 "miR-21, miR-155, miR-210, miR-221, and miR-222, were overexpressed in diseased tissues than in the control samples, whereas miR-31, miR-122, miR-145, and miR-146a were underexpressed." tissue_expression_down hsa-mir-513a-1 Retinoblastoma 22886978 miR-513a-5p expression was decreased in Rb cells after etoposide treatment. tissue_expression_down hsa-mir-513a-2 Retinoblastoma 22886978 miR-513a-5p expression was decreased in Rb cells after etoposide treatment. tissue_expression_down hsa-mir-513b Retinoblastoma 22886978 miR-513a-5p expression was decreased in Rb cells after etoposide treatment. tissue_expression_down hsa-mir-513c Retinoblastoma 22886978 miR-513a-5p expression was decreased in Rb cells after etoposide treatment. tissue_expression_down hsa-mir-125b-1 Breast Neoplasms 22898264 "Upregulation of miR-21 and miR-191 and downregulation of miR-125b, was found in breast cancer tissue." tissue_expression_down hsa-mir-125b-2 Breast Neoplasms 22898264 "Upregulation of miR-21 and miR-191 and downregulation of miR-125b, was found in breast cancer tissue." tissue_expression_down hsa-mir-191 Breast Neoplasms 22898264 "Upregulation of miR-21 and miR-191 and downregulation of miR-125b, was found in breast cancer tissue." tissue_expression_down hsa-mir-21 Breast Neoplasms 22898264 "Upregulation of miR-21 and miR-191 and downregulation of miR-125b, was found in breast cancer tissue." tissue_expression_down hsa-mir-1308 Melanoma 22898827 "we assayed the MITF-KD miRNA profiles using a miRNA microarray and found that hsa-miR-1225-3p, hsa-miR-634, hsa-miR-197, hsa-miR-766, hsa-miR-574-5p and hsa-miR-328 were upregulated, and hsa-miR-720 and hsa-miR-1308 were downregulated in MITF knocked down melanocytes." tissue_expression_down hsa-mir-720 Melanoma 22898827 "we assayed the MITF-KD miRNA profiles using a miRNA microarray and found that hsa-miR-1225-3p, hsa-miR-634, hsa-miR-197, hsa-miR-766, hsa-miR-574-5p and hsa-miR-328 were upregulated, and hsa-miR-720 and hsa-miR-1308 were downregulated in MITF knocked down melanocytes." tissue_expression_down hsa-mir-19b-2 "Tuberculosis, Pulmonary" 22900099 miR-19b-2*: Underexpression tissue_expression_down hsa-mir-199a-1 Colorectal Carcinoma 22903020 "miR-199a-5p was expressed at a low level in human primary colonic epithelial cells treated with deoxycholic acid compared with control, and miR-199a-5p was significantly down-regulated in colorectal cancer tissues.CAC1 was a direct miR-199a-5p target.The high miR-199a-5p expression and low CAC1 protein expression reverse the tumor cell drug resistance." tissue_expression_down hsa-mir-199a-2 Colorectal Carcinoma 22903020 "miR-199a-5p was expressed at a low level in human primary colonic epithelial cells treated with deoxycholic acid compared with control, and miR-199a-5p was significantly down-regulated in colorectal cancer tissues.CAC1 was a direct miR-199a-5p target.The high miR-199a-5p expression and low CAC1 protein expression reverse the tumor cell drug resistance." tissue_expression_down hsa-mir-143 Pancreatic Neoplasms 22905187 "miR-216a, -196a, -143 und -155) were detected at lower concentrations in feces of PCA patients when compared to controls (p<0.05)." tissue_expression_down hsa-mir-155 Pancreatic Neoplasms 22905187 "miR-216a, -196a, -143 und -155) were detected at lower concentrations in feces of PCA patients when compared to controls (p<0.05)." tissue_expression_down hsa-mir-196a-1 Pancreatic Neoplasms 22905187 "miR-216a, -196a, -143 und -155) were detected at lower concentrations in feces of PCA patients when compared to controls (p<0.05)." tissue_expression_down hsa-mir-196a-2 Pancreatic Neoplasms 22905187 "miR-216a, -196a, -143 und -155) were detected at lower concentrations in feces of PCA patients when compared to controls (p<0.05)." tissue_expression_down hsa-mir-216a Pancreatic Neoplasms 22905187 "miR-216a, -196a, -143 und -155) were detected at lower concentrations in feces of PCA patients when compared to controls (p<0.05)." tissue_expression_down hsa-mir-129-1 Breast Neoplasms 22907300 "miR-129 is found to significantly inhibit the migration of MDA-MB-231 both in Transwell migration assay and wound healing assay. Furthermore, miR-129 also shows great suppressive ability to cell mobility and migration in another two breast cancer cell lines BT549 and MDA-MB-435s. Most importantly, miR-129 is down-regulated both in breast cancer tissues compared with the paired adjacent normal breast tissues, and in breast cancer cell lines compared with normal breast epithelial cell MCF10A (P < 0.05)." tissue_expression_down hsa-mir-129-2 Breast Neoplasms 22907300 "miR-129 is found to significantly inhibit the migration of MDA-MB-231 both in Transwell migration assay and wound healing assay. Furthermore, miR-129 also shows great suppressive ability to cell mobility and migration in another two breast cancer cell lines BT549 and MDA-MB-435s. Most importantly, miR-129 is down-regulated both in breast cancer tissues compared with the paired adjacent normal breast tissues, and in breast cancer cell lines compared with normal breast epithelial cell MCF10A (P < 0.05)." tissue_expression_down hsa-mir-100 Endometrial Neoplasms 22920721 "Deregulation of miR-100, miR-99a and miR-199b in tissues and plasma coexists with increased expression of mTOR kinase in endometrioid endometrial carcinoma." tissue_expression_down hsa-mir-128-1 Glioblastoma 22922228 "Platelet-derived growth factor-B (PDGF-B), a potent angiogenic growth factor involved in GBM development and progression, promotes downregulation of pro-oncogenic (miR-21) and anti-oncogenic (miR-128) miRNAs in GBM pathology." tissue_expression_down hsa-mir-128-2 Glioblastoma 22922228 "Platelet-derived growth factor-B (PDGF-B), a potent angiogenic growth factor involved in GBM development and progression, promotes downregulation of pro-oncogenic (miR-21) and anti-oncogenic (miR-128) miRNAs in GBM pathology." tissue_expression_down hsa-mir-21 Glioblastoma 22922228 "Platelet-derived growth factor-B (PDGF-B), a potent angiogenic growth factor involved in GBM development and progression, promotes downregulation of pro-oncogenic (miR-21) and anti-oncogenic (miR-128) miRNAs in GBM pathology." tissue_expression_down hsa-mir-124 Glioblastoma 22929615 "We tested two predicted proneural drivers, miR-124 and miR-132, both underexpressed in proneural tumors, by overexpression in neurospheres and observed a partial reversal of corresponding tumor expression changes." tissue_expression_down hsa-mir-132 Glioblastoma 22929615 "We tested two predicted proneural drivers, miR-124 and miR-132, both underexpressed in proneural tumors, by overexpression in neurospheres and observed a partial reversal of corresponding tumor expression changes." tissue_expression_down hsa-let-7c Pancreatic Neoplasms 22929886 "The expression of let-7c, let-7f, and miR-200c were significantly reduced in most patients whereas the expression of miR-486-5p and miR-451 were significantly elevated in all pancreas cancer patients." tissue_expression_down hsa-let-7f-1 Pancreatic Neoplasms 22929886 "The expression of let-7c, let-7f, and miR-200c were significantly reduced in most patients whereas the expression of miR-486-5p and miR-451 were significantly elevated in all pancreas cancer patients." tissue_expression_down hsa-let-7f-2 Pancreatic Neoplasms 22929886 "The expression of let-7c, let-7f, and miR-200c were significantly reduced in most patients whereas the expression of miR-486-5p and miR-451 were significantly elevated in all pancreas cancer patients." tissue_expression_down hsa-mir-200c Pancreatic Neoplasms 22929886 "The expression of let-7c, let-7f, and miR-200c were significantly reduced in most patients whereas the expression of miR-486-5p and miR-451 were significantly elevated in all pancreas cancer patients." tissue_expression_down hsa-mir-223 Inflammation 22937006 Here we reported that the expression of microRNA-223 (miR-223) was significantly decreased in murine macrophages during activation by lipopolysaccharide (LPS) or poly (I¡ÃC) stimulation. tissue_expression_down hsa-mir-134 "Carcinoma, Lung, Non-Small-Cell" 22937028 "High expression of miR-100 and low expression of miRNA-93, miRNA-134, miRNA-151 and miRNA-345 were associated with poor survival in both the training and validation cohort." tissue_expression_down hsa-mir-151a "Carcinoma, Lung, Non-Small-Cell" 22937028 "High expression of miR-100 and low expression of miRNA-93, miRNA-134, miRNA-151 and miRNA-345 were associated with poor survival in both the training and validation cohort." tissue_expression_down hsa-mir-151b "Carcinoma, Lung, Non-Small-Cell" 22937028 "High expression of miR-100 and low expression of miRNA-93, miRNA-134, miRNA-151 and miRNA-345 were associated with poor survival in both the training and validation cohort." tissue_expression_down hsa-mir-345 "Carcinoma, Lung, Non-Small-Cell" 22937028 "High expression of miR-100 and low expression of miRNA-93, miRNA-134, miRNA-151 and miRNA-345 were associated with poor survival in both the training and validation cohort." tissue_expression_down hsa-mir-93 "Carcinoma, Lung, Non-Small-Cell" 22937028 "High expression of miR-100 and low expression of miRNA-93, miRNA-134, miRNA-151 and miRNA-345 were associated with poor survival in both the training and validation cohort." tissue_expression_down hsa-mir-193a Atrial Fibrillation 22944230 "MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation." tissue_expression_down hsa-let-7g Breast Neoplasms 22964023 "We identified 11 dysregulated miRNAs in CAFs: three were up-regulated (miR-221-5p, miR-31-3p, miR-221-3p), while eight were down-regulated (miR-205, miR-200b, miR-200c, miR-141, miR-101,miR-342-3p, let-7g, miR-26b)" tissue_expression_down hsa-mir-101 Breast Neoplasms 22964023 "We identified 11 dysregulated miRNAs in CAFs: three were up-regulated (miR-221-5p, miR-31-3p, miR-221-3p), while eight were down-regulated (miR-205, miR-200b, miR-200c, miR-141, miR-101,miR-342-3p, let-7g, miR-26b)" tissue_expression_down hsa-mir-141 Breast Neoplasms 22964023 "We identified 11 dysregulated miRNAs in CAFs: three were up-regulated (miR-221-5p, miR-31-3p, miR-221-3p), while eight were down-regulated (miR-205, miR-200b, miR-200c, miR-141, miR-101,miR-342-3p, let-7g, miR-26b)" tissue_expression_down hsa-mir-200b Breast Neoplasms 22964023 "We identified 11 dysregulated miRNAs in CAFs: three were up-regulated (miR-221-5p, miR-31-3p, miR-221-3p), while eight were down-regulated (miR-205, miR-200b, miR-200c, miR-141, miR-101,miR-342-3p, let-7g, miR-26b)" tissue_expression_down hsa-mir-200c Breast Neoplasms 22964023 "We identified 11 dysregulated miRNAs in CAFs: three were up-regulated (miR-221-5p, miR-31-3p, miR-221-3p), while eight were down-regulated (miR-205, miR-200b, miR-200c, miR-141, miR-101,miR-342-3p, let-7g, miR-26b)" tissue_expression_down hsa-mir-205 Breast Neoplasms 22964023 "We identified 11 dysregulated miRNAs in CAFs: three were up-regulated (miR-221-5p, miR-31-3p, miR-221-3p), while eight were down-regulated (miR-205, miR-200b, miR-200c, miR-141, miR-101,miR-342-3p, let-7g, miR-26b)" tissue_expression_down hsa-mir-26b Breast Neoplasms 22964023 "We identified 11 dysregulated miRNAs in CAFs: three were up-regulated (miR-221-5p, miR-31-3p, miR-221-3p), while eight were down-regulated (miR-205, miR-200b, miR-200c, miR-141, miR-101,miR-342-3p, let-7g, miR-26b)" tissue_expression_down hsa-mir-342 Breast Neoplasms 22964023 "We identified 11 dysregulated miRNAs in CAFs: three were up-regulated (miR-221-5p, miR-31-3p, miR-221-3p), while eight were down-regulated (miR-205, miR-200b, miR-200c, miR-141, miR-101,miR-342-3p, let-7g, miR-26b)" tissue_expression_down hsa-mir-146a Tuberculosis 22964481 "we observed that miR-146a expression is also down-regulated in tuberculosis patients, both in PBMCs and PFMCs while miR-424 levels are elevated only in the peripheral compartments." tissue_expression_down hsa-mir-146 Prion Diseases 22965126 "we show that exosomes released by prion-infected neuronal cells have increased let-7b, let-7i, miR-128a, miR-21, miR-222, miR-29b,miR-342-3p and miR-424 levels with decreased miR-146 a levels compared to non-infected exosomes." tissue_expression_down hsa-mir-10a "Squamous Cell Carcinoma, Esophageal" 22966337 Down-regulation of microRNA 10a expression in esophageal squamous cell carcinoma cells. tissue_expression_down hsa-mir-181a "Leukemia, Promyelocytic, Acute" 22967415 "The expression level of miR-15b, miR-16, miR-107, miR-223 and miR-342 in APL CR group were significantly upregulated compared with that of newly diagnosed APL groups (P < 0.05), while the expression level of miR-181a was significantly downregulated (P < 0.05)." tissue_expression_down hsa-mir-10a "Carcinoma, Hepatocellular" 22976466 "Significant downregulation of miR-10a was observed in tumor compared with non-tumor tissues (0.50 vs. 1.73, p = 0.031)." tissue_expression_down hsa-mir-143 Cervical Neoplasms 22997891 "The high expression of miR-21 in cervical cancer and Hela cell indicate that it may play a possible role of oncogenes, while miR-143 and miR-373 with low expression may play the role of tumor suppressor genes." tissue_expression_down hsa-mir-373 Cervical Neoplasms 22997891 "The high expression of miR-21 in cervical cancer and Hela cell indicate that it may play a possible role of oncogenes, while miR-143 and miR-373 with low expression may play the role of tumor suppressor genes." tissue_expression_down hsa-mir-100 Prostate Neoplasms 22999546 "miR-100 and miR-10a showed under expression and over expression, respectively, in low grade pTa tumors." tissue_expression_down hsa-mir-140 "Squamous Cell Carcinoma, Skin or Unspecific" 23026055 "Non-stringent filtering with a non-adjusted p ¡Ü 0.01 revealed three up-regulated (hsa-miR-135b, hsa-miR-424 and hsa-miR-766) and six down-regulated (hsa-miR-30a*, hsa-miR-378, hsa-miR-145, hsa-miR-140-3p, hsa-miR-30a and hsa-miR-26a) miRNAs in cSCC" tissue_expression_down hsa-mir-145 "Squamous Cell Carcinoma, Skin or Unspecific" 23026055 "Non-stringent filtering with a non-adjusted p ¡Ü 0.01 revealed three up-regulated (hsa-miR-135b, hsa-miR-424 and hsa-miR-766) and six down-regulated (hsa-miR-30a*, hsa-miR-378, hsa-miR-145, hsa-miR-140-3p, hsa-miR-30a and hsa-miR-26a) miRNAs in cSCC" tissue_expression_down hsa-mir-26a "Squamous Cell Carcinoma, Skin or Unspecific" 23026055 "Non-stringent filtering with a non-adjusted p ¡Ü 0.01 revealed three up-regulated (hsa-miR-135b, hsa-miR-424 and hsa-miR-766) and six down-regulated (hsa-miR-30a*, hsa-miR-378, hsa-miR-145, hsa-miR-140-3p, hsa-miR-30a and hsa-miR-26a) miRNAs in cSCC" tissue_expression_down hsa-mir-30a "Squamous Cell Carcinoma, Skin or Unspecific" 23026055 "Non-stringent filtering with a non-adjusted p ¡Ü 0.01 revealed three up-regulated (hsa-miR-135b, hsa-miR-424 and hsa-miR-766) and six down-regulated (hsa-miR-30a*, hsa-miR-378, hsa-miR-145, hsa-miR-140-3p, hsa-miR-30a and hsa-miR-26a) miRNAs in cSCC" tissue_expression_down hsa-mir-378 "Squamous Cell Carcinoma, Skin or Unspecific" 23026055 "Non-stringent filtering with a non-adjusted p ¡Ü 0.01 revealed three up-regulated (hsa-miR-135b, hsa-miR-424 and hsa-miR-766) and six down-regulated (hsa-miR-30a*, hsa-miR-378, hsa-miR-145, hsa-miR-140-3p, hsa-miR-30a and hsa-miR-26a) miRNAs in cSCC" tissue_expression_down hsa-mir-199a-1 Neoplasms [unspecific] 23060436 The microRNA miR-199a-5p down-regulation switches on wound angiogenesis by derepressing the v-ets erythroblastosis virus E26 oncogene homolog 1-matrix metalloproteinase-1 pathway tissue_expression_down hsa-mir-199a-2 Neoplasms [unspecific] 23060436 The microRNA miR-199a-5p down-regulation switches on wound angiogenesis by derepressing the v-ets erythroblastosis virus E26 oncogene homolog 1-matrix metalloproteinase-1 pathway tissue_expression_down hsa-mir-328 Glioblastoma 23077581 MiR-328 expression is decreased in high-grade gliomas and is associated with worse survival in primary glioblastoma tissue_expression_down hsa-mir-1275 "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_down hsa-mir-138 "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_down hsa-mir-199a "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_down hsa-mir-214 "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_down hsa-mir-433 "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_down hsa-mir-483 "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_down hsa-mir-511 "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_down hsa-mir-592 "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_down hsa-mir-708 "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_down hsa-mir-106b "Carcinoma, Hepatocellular" 23087084 miR-106b downregulates adenomatous polyposis coli and promotes cell proliferation in human hepatocellular carcinoma tissue_expression_down hsa-let-7c Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_down hsa-mir-100 Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_down hsa-mir-125b Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_down hsa-mir-145 Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_down hsa-mir-203 Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_down hsa-mir-205 Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_down hsa-mir-27b Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_down hsa-mir-375 Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_down hsa-mir-375 Glioma 23103713 Correlation of microRNA-375 downregulation with unfavorable clinical outcome of patients with glioma tissue_expression_down hsa-mir-145 Meningioma 23108408 miRNA-145 is downregulated in atypical and anaplastic meningiomas and negatively regulates motility and proliferation of meningioma cells tissue_expression_down hsa-mir-24-1 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_down hsa-mir-26a Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_down hsa-mir-4291 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_down hsa-mir-4317 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_down hsa-mir-4324 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_down hsa-mir-204 Pulmonary Hypertension 23114789 "MEX suppressed the hypoxic activation of signal transducer and activator of transcription 3 (STAT3) and the upregulation of the miR-17 superfamily of microRNA clusters, whereas it increased lung levels of miR-204, a key microRNA, the expression of which is decreased in human pulmonary hypertension." tissue_expression_down hsa-mir-10b Breast Neoplasms 23125021 "miR-10b*, a master inhibitor of the cell cycle, is down-regulated in human breast tumours" tissue_expression_down hsa-mir-495 Leukemia 23132946 MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia tissue_expression_down hsa-mir-224 Prostate Neoplasms 23136246 Downregulation and Prognostic Performance of MicroRNA 224 Expression in Prostate Cancer tissue_expression_down hsa-mir-383 Medulloblastoma 23157748 "Compared with normal brain tissue, decreased expression of miR-383 but elevated expression of PRDX3 are medulloblastoma tumour and Daoy cell lines" tissue_expression_down hsa-mir-1 Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_down hsa-mir-1281 Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_down hsa-mir-133a Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_down hsa-mir-133b Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_down hsa-mir-143 Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_down hsa-mir-145 Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_down hsa-mir-199a Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_down hsa-mir-199b Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_down hsa-mir-204 Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_down hsa-mir-921 Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_down hsa-mir-192 Asthma 23170939 MiR-192 was technically validated using real-time reverse transcription-quantitative polymerase chain reaction (RT-qPCR) showing that the level in asthmatics (pre-challenge) was significantly lower than HCs and that post-challenge was significantly lower than pre-challenge. tissue_expression_down hsa-mir-214 Ovarian Neoplasms 23171795 "We found that in ovarian CAFs, miR-31 and miR-214 were downregulated, whereas miR-155 was upregulated when compared with normal or tumor-adjacent fibroblasts." tissue_expression_down hsa-mir-31 Ovarian Neoplasms 23171795 "We found that in ovarian CAFs, miR-31 and miR-214 were downregulated, whereas miR-155 was upregulated when compared with normal or tumor-adjacent fibroblasts." tissue_expression_down hsa-mir-199a-1 "Carcinoma, Renal Cell" 23174576 "A decreased expression of miR-199a is significantly correlated with a higher tumor stage, a greater likeliness of tumor recurrence, and a poorer prognosis in RCC patients" tissue_expression_down hsa-mir-199a-2 "Carcinoma, Renal Cell" 23174576 "A decreased expression of miR-199a is significantly correlated with a higher tumor stage, a greater likeliness of tumor recurrence, and a poorer prognosis in RCC patients" tissue_expression_down hsa-mir-216a Pancreatic Neoplasms 23174591 The down-regulated expression of miR-216a in pancreatic cancer suggests the involvement of miR-216a in the tumorigenesis and development of pancreatic cancer tissue_expression_down hsa-mir-106a Colorectal Carcinoma 23178825 miR-106a overexpression and pRB downregulation in sporadic colorectal cancer tissue_expression_down hsa-mir-153-1 Neoplasms [unspecific] 23188671 Downregulation of miR-153 contributes to epithelial-mesenchymal transition and tumor metastasis in human epithelial cancer tissue_expression_down hsa-mir-153-2 Neoplasms [unspecific] 23188671 Downregulation of miR-153 contributes to epithelial-mesenchymal transition and tumor metastasis in human epithelial cancer tissue_expression_down hsa-mir-26a-1 Melanoma 23190898 MicroRNA-26a Is Strongly Downregulated in Melanoma and Induces Cell Death through Repression of Silencer of Death Domains tissue_expression_down hsa-mir-26a-2 Melanoma 23190898 MicroRNA-26a Is Strongly Downregulated in Melanoma and Induces Cell Death through Repression of Silencer of Death Domains tissue_expression_down hsa-mir-421 "Squamous Cell Carcinoma, Skin or Unspecific" 23199656 Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma tissue_expression_down hsa-mir-186 Lung Neoplasms 23204228 "miR-186 Downregulation Correlates with Poor Survival in Lung Adenocarcinoma,Where It Interferes with Cell-Cycle Regulation" tissue_expression_down hsa-mir-1228 "Carcinoma, Hepatocellular" 23205106 "The following miRNAs were downregulated in the tumor and non-tumor tissues, and thus could serve as novel biomarkers for chronic liver diseases: miR-18b*, miR-296-5p, miR-557, miR-581, miR-625*, miR-1228, miR-1249 and miR-2116*. Similarly, miR-129*, miR-146b-3p and miR-448 are novel candidates for HCC biomarkers regardless of virus infection." tissue_expression_down hsa-mir-1249 "Carcinoma, Hepatocellular" 23205106 "The following miRNAs were downregulated in the tumor and non-tumor tissues, and thus could serve as novel biomarkers for chronic liver diseases: miR-18b*, miR-296-5p, miR-557, miR-581, miR-625*, miR-1228, miR-1249 and miR-2116*. Similarly, miR-129*, miR-146b-3p and miR-448 are novel candidates for HCC biomarkers regardless of virus infection." tissue_expression_down hsa-mir-129 "Carcinoma, Hepatocellular" 23205106 "The following miRNAs were downregulated in the tumor and non-tumor tissues, and thus could serve as novel biomarkers for chronic liver diseases: miR-18b*, miR-296-5p, miR-557, miR-581, miR-625*, miR-1228, miR-1249 and miR-2116*. Similarly, miR-129*, miR-146b-3p and miR-448 are novel candidates for HCC biomarkers regardless of virus infection." tissue_expression_down hsa-mir-146 "Carcinoma, Hepatocellular" 23205106 "The following miRNAs were downregulated in the tumor and non-tumor tissues, and thus could serve as novel biomarkers for chronic liver diseases: miR-18b*, miR-296-5p, miR-557, miR-581, miR-625*, miR-1228, miR-1249 and miR-2116*. Similarly, miR-129*, miR-146b-3p and miR-448 are novel candidates for HCC biomarkers regardless of virus infection." tissue_expression_down hsa-mir-18b "Carcinoma, Hepatocellular" 23205106 "The following miRNAs were downregulated in the tumor and non-tumor tissues, and thus could serve as novel biomarkers for chronic liver diseases: miR-18b*, miR-296-5p, miR-557, miR-581, miR-625*, miR-1228, miR-1249 and miR-2116*. Similarly, miR-129*, miR-146b-3p and miR-448 are novel candidates for HCC biomarkers regardless of virus infection." tissue_expression_down hsa-mir-2116 "Carcinoma, Hepatocellular" 23205106 "The following miRNAs were downregulated in the tumor and non-tumor tissues, and thus could serve as novel biomarkers for chronic liver diseases: miR-18b*, miR-296-5p, miR-557, miR-581, miR-625*, miR-1228, miR-1249 and miR-2116*. Similarly, miR-129*, miR-146b-3p and miR-448 are novel candidates for HCC biomarkers regardless of virus infection." tissue_expression_down hsa-mir-296 "Carcinoma, Hepatocellular" 23205106 "The following miRNAs were downregulated in the tumor and non-tumor tissues, and thus could serve as novel biomarkers for chronic liver diseases: miR-18b*, miR-296-5p, miR-557, miR-581, miR-625*, miR-1228, miR-1249 and miR-2116*. Similarly, miR-129*, miR-146b-3p and miR-448 are novel candidates for HCC biomarkers regardless of virus infection." tissue_expression_down hsa-mir-448 "Carcinoma, Hepatocellular" 23205106 "The following miRNAs were downregulated in the tumor and non-tumor tissues, and thus could serve as novel biomarkers for chronic liver diseases: miR-18b*, miR-296-5p, miR-557, miR-581, miR-625*, miR-1228, miR-1249 and miR-2116*. Similarly, miR-129*, miR-146b-3p and miR-448 are novel candidates for HCC biomarkers regardless of virus infection." tissue_expression_down hsa-mir-557 "Carcinoma, Hepatocellular" 23205106 "The following miRNAs were downregulated in the tumor and non-tumor tissues, and thus could serve as novel biomarkers for chronic liver diseases: miR-18b*, miR-296-5p, miR-557, miR-581, miR-625*, miR-1228, miR-1249 and miR-2116*. Similarly, miR-129*, miR-146b-3p and miR-448 are novel candidates for HCC biomarkers regardless of virus infection." tissue_expression_down hsa-mir-581 "Carcinoma, Hepatocellular" 23205106 "The following miRNAs were downregulated in the tumor and non-tumor tissues, and thus could serve as novel biomarkers for chronic liver diseases: miR-18b*, miR-296-5p, miR-557, miR-581, miR-625*, miR-1228, miR-1249 and miR-2116*. Similarly, miR-129*, miR-146b-3p and miR-448 are novel candidates for HCC biomarkers regardless of virus infection." tissue_expression_down hsa-mir-625 "Carcinoma, Hepatocellular" 23205106 "The following miRNAs were downregulated in the tumor and non-tumor tissues, and thus could serve as novel biomarkers for chronic liver diseases: miR-18b*, miR-296-5p, miR-557, miR-581, miR-625*, miR-1228, miR-1249 and miR-2116*. Similarly, miR-129*, miR-146b-3p and miR-448 are novel candidates for HCC biomarkers regardless of virus infection." tissue_expression_down hsa-mir-544a Glioma 23205130 "Downregulation of miR-544 in tissue, but not in serum, is a novel biomarker of malignant transformation in glioma" tissue_expression_down hsa-mir-544b Glioma 23205130 "Downregulation of miR-544 in tissue, but not in serum, is a novel biomarker of malignant transformation in glioma" tissue_expression_down hsa-mir-141 "Carcinoma, Renal Cell" 23206420 A possible role for micro-RNA 141 down-regulation in sunitinib resistant metastatic clear cell renal cell carcinoma through induction of epithelial-to-mesenchymal transition and hypoxia resistance tissue_expression_down hsa-mir-26b "Carcinoma, Lung, Non-Small-Cell" 23207443 SQCC was distinguished from normal tissue and ADC by high-level miR-205 expression and decreased miR-26b. tissue_expression_down hsa-mir-107 Glioma 23220650 P53-induced microRNA-107 inhibits proliferation of glioma cells and down-regulates the expression of CDK6 and Notch-2 tissue_expression_down hsa-mir-150 "Carcinoma, Lung, Non-Small-Cell" 23228962 Expression of miR-150 and miR-3940-5p is reduced in non-small cell lung carcinoma and correlates with clinicopathological features tissue_expression_down hsa-mir-3940 "Carcinoma, Lung, Non-Small-Cell" 23228962 Expression of miR-150 and miR-3940-5p is reduced in non-small cell lung carcinoma and correlates with clinicopathological features tissue_expression_down hsa-mir-214 Ovarian Neoplasms 23230184 They found that decreased miR-31 and miR-214 and increased miR-155 expression can reprogram normal fibroblasts into tumor-promoting cancer-associated fibroblasts. tissue_expression_down hsa-mir-31 Ovarian Neoplasms 23230184 They found that decreased miR-31 and miR-214 and increased miR-155 expression can reprogram normal fibroblasts into tumor-promoting cancer-associated fibroblasts. tissue_expression_down hsa-mir-326 Glioma 23292865 "Down-regulation of miR-326 may have potential value for predicting clinical outcomes in glioma patients with high pathological grades, suggesting that miR-326 is an important candidate tumor suppressor, and its down-regulated expression may contribute to glioma progression" tissue_expression_down hsa-mir-9 Waldenstrom Macroglobulinemia 23301642 The most important changes of microRNA are increased expression of miR-155 and decreased expression of miR-9*. tissue_expression_down hsa-mir-125b-1 Systemic Lupus Erythematosus 23305626 "Further analysis showed that the down-regulation of miR-125b, mainly in T cells, was negatively correlated with lupus nephritis" tissue_expression_down hsa-mir-125b-2 Systemic Lupus Erythematosus 23305626 "Further analysis showed that the down-regulation of miR-125b, mainly in T cells, was negatively correlated with lupus nephritis" tissue_expression_down hsa-mir-30c-1 Neoplasms [unspecific] 23318178 Sulfuretin-induced miR-30C selectively downregulates cyclin D1 and D2 and triggers cell death in human cancer cell lines tissue_expression_down hsa-mir-30c-2 Neoplasms [unspecific] 23318178 Sulfuretin-induced miR-30C selectively downregulates cyclin D1 and D2 and triggers cell death in human cancer cell lines tissue_expression_down hsa-mir-150 Myocardial Infarction 23326587 "Adenosine increases the migration of EPC. The mechanism involves A(2B) receptor activation, decreased expression of miR-150 and increased expression of CXCR4." tissue_expression_down hsa-mir-214 Urinary Bladder Cancer 23337879 MiR-214 reduces cell survival and enhances cisplatin-induced cytotoxicity via down-regulation of Bcl2l2 in cervical cancer cells tissue_expression_down hsa-let-7 Pancreatic Neoplasms 23338123 "The BxPC-3-LN cells expressed lower levels of let-7, miR-34, miR-107, miR-125, miR-128, miR-130, miR-132 and miR-141 than the parental BxPC-3 cells detected by microRNA PCR array, which were reported to have close relation to stem cell factors." tissue_expression_down hsa-mir-107 Pancreatic Neoplasms 23338123 "The BxPC-3-LN cells expressed lower levels of let-7, miR-34, miR-107, miR-125, miR-128, miR-130, miR-132 and miR-141 than the parental BxPC-3 cells detected by microRNA PCR array, which were reported to have close relation to stem cell factors." tissue_expression_down hsa-mir-125 Pancreatic Neoplasms 23338123 "The BxPC-3-LN cells expressed lower levels of let-7, miR-34, miR-107, miR-125, miR-128, miR-130, miR-132 and miR-141 than the parental BxPC-3 cells detected by microRNA PCR array, which were reported to have close relation to stem cell factors." tissue_expression_down hsa-mir-128 Pancreatic Neoplasms 23338123 "The BxPC-3-LN cells expressed lower levels of let-7, miR-34, miR-107, miR-125, miR-128, miR-130, miR-132 and miR-141 than the parental BxPC-3 cells detected by microRNA PCR array, which were reported to have close relation to stem cell factors." tissue_expression_down hsa-mir-130 Pancreatic Neoplasms 23338123 "The BxPC-3-LN cells expressed lower levels of let-7, miR-34, miR-107, miR-125, miR-128, miR-130, miR-132 and miR-141 than the parental BxPC-3 cells detected by microRNA PCR array, which were reported to have close relation to stem cell factors." tissue_expression_down hsa-mir-132 Pancreatic Neoplasms 23338123 "The BxPC-3-LN cells expressed lower levels of let-7, miR-34, miR-107, miR-125, miR-128, miR-130, miR-132 and miR-141 than the parental BxPC-3 cells detected by microRNA PCR array, which were reported to have close relation to stem cell factors." tissue_expression_down hsa-mir-141 Pancreatic Neoplasms 23338123 "The BxPC-3-LN cells expressed lower levels of let-7, miR-34, miR-107, miR-125, miR-128, miR-130, miR-132 and miR-141 than the parental BxPC-3 cells detected by microRNA PCR array, which were reported to have close relation to stem cell factors." tissue_expression_down hsa-mir-34 Pancreatic Neoplasms 23338123 "The BxPC-3-LN cells expressed lower levels of let-7, miR-34, miR-107, miR-125, miR-128, miR-130, miR-132 and miR-141 than the parental BxPC-3 cells detected by microRNA PCR array, which were reported to have close relation to stem cell factors." tissue_expression_down hsa-mir-93 Colorectal Carcinoma 23354160 "the downregulation of miR-93 was significantly correlated with unfavorable clinicopathologic features and short overall survival in patients with colon cancer, suggesting that decreased expression of miR-93 be used as a novel prognostic factor for this disease" tissue_expression_down hsa-mir-34a Colorectal Carcinoma 23355243 The down-regulated expression of miR-34a in colorectal cancer patients is associated with recurrence after radical operation tissue_expression_down hsa-mir-132 Breast Neoplasms 23399321 MicroRNA-132 is frequently down-regulated in ductal carcinoma in situ (DCIS) of breast and acts as a tumor suppressor by inhibiting cell proliferation tissue_expression_down hsa-mir-31 Urinary Bladder Cancer 23408039 Decreased expression of microRNA-31 associates with aggressive tumor progression and poor prognosis in patients with bladder cancer tissue_expression_down hsa-mir-130a Chronic Hepatitis C 23418453 "Seven miRNAs (miR-30b, miR-30c, miR-130a, miR-192, miR-301, miR-324-5p, and miR-565) were down-regulated in HCV-infected Huh7.5 cells (p<0.05) and subsequently up-regulated following interferon-¦Á treatment (p<0.01)" tissue_expression_down hsa-mir-192 Chronic Hepatitis C 23418453 "Seven miRNAs (miR-30b, miR-30c, miR-130a, miR-192, miR-301, miR-324-5p, and miR-565) were down-regulated in HCV-infected Huh7.5 cells (p<0.05) and subsequently up-regulated following interferon-¦Á treatment (p<0.01)" tissue_expression_down hsa-mir-301 Chronic Hepatitis C 23418453 "Seven miRNAs (miR-30b, miR-30c, miR-130a, miR-192, miR-301, miR-324-5p, and miR-565) were down-regulated in HCV-infected Huh7.5 cells (p<0.05) and subsequently up-regulated following interferon-¦Á treatment (p<0.01)" tissue_expression_down hsa-mir-30b Chronic Hepatitis C 23418453 "Seven miRNAs (miR-30b, miR-30c, miR-130a, miR-192, miR-301, miR-324-5p, and miR-565) were down-regulated in HCV-infected Huh7.5 cells (p<0.05) and subsequently up-regulated following interferon-¦Á treatment (p<0.01)" tissue_expression_down hsa-mir-30c Chronic Hepatitis C 23418453 "Seven miRNAs (miR-30b, miR-30c, miR-130a, miR-192, miR-301, miR-324-5p, and miR-565) were down-regulated in HCV-infected Huh7.5 cells (p<0.05) and subsequently up-regulated following interferon-¦Á treatment (p<0.01)" tissue_expression_down hsa-mir-324 Chronic Hepatitis C 23418453 "Seven miRNAs (miR-30b, miR-30c, miR-130a, miR-192, miR-301, miR-324-5p, and miR-565) were down-regulated in HCV-infected Huh7.5 cells (p<0.05) and subsequently up-regulated following interferon-¦Á treatment (p<0.01)" tissue_expression_down hsa-mir-565 Chronic Hepatitis C 23418453 "Seven miRNAs (miR-30b, miR-30c, miR-130a, miR-192, miR-301, miR-324-5p, and miR-565) were down-regulated in HCV-infected Huh7.5 cells (p<0.05) and subsequently up-regulated following interferon-¦Á treatment (p<0.01)" tissue_expression_down hsa-mir-17 Colon Neoplasms 23436804 "We detect and confirm 27 miRNAs to be significantly changed following ER¦Â expression in SW480 colon cancer cells. Among these, the oncogenic miR-17-92 cluster and miR-200a/b are strongly downregulated. Using target prediction and anticorrelation to gene expression data followed by focused mechanistic studies, we demonstrate that repression of miR-17 is a secondary event following ER¦Â's downregulatory effect on MYC. " tissue_expression_down hsa-mir-18 Colon Neoplasms 23436804 "We detect and confirm 27 miRNAs to be significantly changed following ER¦Â expression in SW480 colon cancer cells. Among these, the oncogenic miR-17-92 cluster and miR-200a/b are strongly downregulated. Using target prediction and anticorrelation to gene expression data followed by focused mechanistic studies, we demonstrate that repression of miR-17 is a secondary event following ER¦Â's downregulatory effect on MYC. " tissue_expression_down hsa-mir-19a Colon Neoplasms 23436804 "We detect and confirm 27 miRNAs to be significantly changed following ER¦Â expression in SW480 colon cancer cells. Among these, the oncogenic miR-17-92 cluster and miR-200a/b are strongly downregulated. Using target prediction and anticorrelation to gene expression data followed by focused mechanistic studies, we demonstrate that repression of miR-17 is a secondary event following ER¦Â's downregulatory effect on MYC. " tissue_expression_down hsa-mir-19b-1 Colon Neoplasms 23436804 "We detect and confirm 27 miRNAs to be significantly changed following ER¦Â expression in SW480 colon cancer cells. Among these, the oncogenic miR-17-92 cluster and miR-200a/b are strongly downregulated. Using target prediction and anticorrelation to gene expression data followed by focused mechanistic studies, we demonstrate that repression of miR-17 is a secondary event following ER¦Â's downregulatory effect on MYC. " tissue_expression_down hsa-mir-200a Colon Neoplasms 23436804 "We detect and confirm 27 miRNAs to be significantly changed following ER¦Â expression in SW480 colon cancer cells. Among these, the oncogenic miR-17-92 cluster and miR-200a/b are strongly downregulated. Using target prediction and anticorrelation to gene expression data followed by focused mechanistic studies, we demonstrate that repression of miR-17 is a secondary event following ER¦Â's downregulatory effect on MYC. " tissue_expression_down hsa-mir-200b Colon Neoplasms 23436804 "We detect and confirm 27 miRNAs to be significantly changed following ER¦Â expression in SW480 colon cancer cells. Among these, the oncogenic miR-17-92 cluster and miR-200a/b are strongly downregulated. Using target prediction and anticorrelation to gene expression data followed by focused mechanistic studies, we demonstrate that repression of miR-17 is a secondary event following ER¦Â's downregulatory effect on MYC. " tissue_expression_down hsa-mir-20a Colon Neoplasms 23436804 "We detect and confirm 27 miRNAs to be significantly changed following ER¦Â expression in SW480 colon cancer cells. Among these, the oncogenic miR-17-92 cluster and miR-200a/b are strongly downregulated. Using target prediction and anticorrelation to gene expression data followed by focused mechanistic studies, we demonstrate that repression of miR-17 is a secondary event following ER¦Â's downregulatory effect on MYC. " tissue_expression_down hsa-mir-92-1 Colon Neoplasms 23436804 "We detect and confirm 27 miRNAs to be significantly changed following ER¦Â expression in SW480 colon cancer cells. Among these, the oncogenic miR-17-92 cluster and miR-200a/b are strongly downregulated. Using target prediction and anticorrelation to gene expression data followed by focused mechanistic studies, we demonstrate that repression of miR-17 is a secondary event following ER¦Â's downregulatory effect on MYC. " tissue_expression_down hsa-mir-200a Gastrointestinal Neoplasms 23456798 It was noteworthy that miR-200a was significantly down-regulated in gastric adenocarcinoma samples (P = .04) but was up-regulated in esophageal adenocarcinoma samples (P = .001). tissue_expression_down hsa-mir-375 "Adenocarcinoma, Gastric" 23461060 "In our study, the expression of a subset of microRNAs was altered in distal gastric adenocarcinoma compared to normal tissue, miR-375 was significantly downregulated in distal gastric adenocarcinoma tissues, to a level that was significantly lower than cardia adenocarcinoma (p < 0.05)." tissue_expression_down hsa-mir-206 Breast Neoplasms 23466356 miR-206 is down-regulated in breast cancer and inhibits cell proliferation through the up-regulation of cyclinD2 tissue_expression_down hsa-mir-371 "Carcinoma, Hepatocellular" 23466643 miR-371-5p down-regulates pre mRNA processing factor 4 homolog B (PRPF4B) and facilitates the G1/S transition in human hepatocellular carcinoma cells tissue_expression_down hsa-mir-135b Esophageal Neoplasms 23477513 patients with either decreased miR-135b or increased miR-145 expression in cancer tissue had improved disease-free survival tissue_expression_down hsa-mir-146a Ischemia-Reperfusion Injury 23498784 Down-regulation of microRNA-146a in the early stage of liver ischemia-reperfusion injury. tissue_expression_down hsa-mir-302b "Adenocarcinoma, Gastric" 23508453 "Down-regulation of miR-302b, an ESC-specific microRNA, in Gastric Adenocarcinoma." tissue_expression_down hsa-let-7i Inflammation 23509825 This let-7i downregulation in dendritic cells constitutes a novel feature of the modulatory activity that helminth-derived antigens exert on their host. tissue_expression_down hsa-mir-145 "Squamous Cell Carcinoma, Oral" 23548968 Downregulation of miR-145 Expression in Oral Squamous Cell Carcinomas and Its Clinical Significance tissue_expression_down hsa-mir-27b Colorectal Carcinoma 23593282 "we demonstrated that miR-27b expression is decreased in most CRC tissues and determined that overexpression of miR-27b represses CRC cell proliferation, colony formation and tumor growth in vitro and in vivo." tissue_expression_down hsa-mir-223 Osteosarcoma 23601845 we found that miRNA-223 was downregulated in both osteosarcoma patients' tumor tissues and osteosarcoma cell lines. tissue_expression_down hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 23615967 "Significant upregulation of miR-150, miR-29c, miR-143 and miR-223 and downregulation of miR-15a was found in mutated versus unmutated CLL, with miR-15a showing the highest fold difference." tissue_expression_down hsa-mir-200a Breast Neoplasms 23626803 Reduced expression of miR-200 family members contributes to antiestrogen resistance in LY2 human breast cancer cells. tissue_expression_down hsa-mir-200b Breast Neoplasms 23626803 Reduced expression of miR-200 family members contributes to antiestrogen resistance in LY2 human breast cancer cells. tissue_expression_down hsa-mir-200c Breast Neoplasms 23626803 Reduced expression of miR-200 family members contributes to antiestrogen resistance in LY2 human breast cancer cells. tissue_expression_down hsa-mir-205 Melanoma 23629002 microRNA (miR)-205 is downregulated and acts as a tumor suppressor in human melanoma cells. tissue_expression_down hsa-let-7e Allergic Rhinitis 23704072 "Subjects with current allergic rhinitis symptoms had increased levels of miR-155, miR-205, and miR-498, but reduced levels of let-7e." tissue_expression_down hsa-mir-125b Bladder Neoplasms 23712207 "miRNAs downregulated in bladder cancer, such as miR-145, miR-143 and miR125b, are known to be tumour suppressors" tissue_expression_down hsa-mir-143 Bladder Neoplasms 23712207 "miRNAs downregulated in bladder cancer, such as miR-145, miR-143 and miR125b, are known to be tumour suppressors" tissue_expression_down hsa-mir-145 Bladder Neoplasms 23712207 "miRNAs downregulated in bladder cancer, such as miR-145, miR-143 and miR125b, are known to be tumour suppressors" tissue_expression_down hsa-mir-1246 Pulmonary Hypertension 23717609 "We identified several novel downregulated miRNAs (miR-451, miR-1246) and upregulated miRNAs (miR-23b, miR-130a and miR-191) in the circulation of PH subjects." tissue_expression_down hsa-mir-451 Pulmonary Hypertension 23717609 "We identified several novel downregulated miRNAs (miR-451, miR-1246) and upregulated miRNAs (miR-23b, miR-130a and miR-191) in the circulation of PH subjects." tissue_expression_down hsa-mir-122 "Carcinoma, Hepatocellular" 23727126 "miR-122, a liver-specific tumor suppressor microRNA, is frequently down-regulated in hepatocellular carcinoma (HCC)" tissue_expression_down hsa-mir-146a Osteoarthritis 23744481 The downregulation of miR-146a and/or the miR-183 cluster in the central compartments (DRG and spinal cord) are closely associated with the upregulation of inflammatory pain mediators. tissue_expression_down hsa-mir-183 Osteoarthritis 23744481 The downregulation of miR-146a and/or the miR-183 cluster in the central compartments (DRG and spinal cord) are closely associated with the upregulation of inflammatory pain mediators. tissue_expression_down hsa-mir-206 Gastric Neoplasms 23751352 Downregulation of microRNA-206 is a potent prognostic marker for patients with gastric cancer. tissue_expression_down hsa-mir-1-1 Lung Neoplasms 23761296 Sustainable downregulation in the lung tissues in lung carcinogenesis induced by urethane. tissue_expression_down hsa-mir-1-2 Lung Neoplasms 23761296 Sustainable downregulation in the lung tissues in lung carcinogenesis induced by urethane. tissue_expression_down hsa-mir-126 Esophageal Neoplasms 23761828 downregulated tissue_expression_down hsa-mir-223 Esophageal Neoplasms 23761828 downregulated tissue_expression_down hsa-mir-30b Esophageal Neoplasms 23761828 downregulated tissue_expression_down hsa-mir-454 Esophageal Neoplasms 23761828 downregulated tissue_expression_down hsa-mir-486 Esophageal Neoplasms 23761828 downregulated tissue_expression_down hsa-mir-574 Esophageal Neoplasms 23761828 miR-574-3p:downregulated tissue_expression_down hsa-mir-22 "Carcinoma, Hepatocellular" 23766411 "miR-22 is downregulated in HCC and its expression is associated with the differentiation, metastasis and prognosis of the carcinoma. Ezrin is a potential regulatory protein of miR-22." tissue_expression_down hsa-mir-21 Colorectal Carcinoma 23773491 "In Taiwan, downregulation of the APC gene in CRC correlated with gene mutation and mir-21 upregulation. APC mutation and mir-21 expression could be used to predict the clinical outcome of CRC, especially in patients with advanced disease." tissue_expression_down hsa-mir-17 "Squamous Cell Carcinoma, Oral" 23780339 "miR-17-5p is induced in irradiated OC3 cells and it downregulates p21 protein expression, contributing to the radioresistance of OC3 cells." tissue_expression_down hsa-mir-205 Hereditary Hemorrhagic Telangiectasia 23800974 MiR-205 is downregulated in hereditary hemorrhagic telangiectasia and impairs TGF-beta signaling pathways in endothelial cells. tissue_expression_down hsa-mir-27a Pancreatic Neoplasms 23803693 "in Panc1 cells metformin decreased microRNA-27a and induced the Sp repressor, ZBTB10, and disruption of miR-27a:ZBTB10 by metformin was phosphatase dependent." tissue_expression_down hsa-mir-34c Lung Neoplasms 23805317 MiR-34a and miR-34c were downregulated in lung tumors compared to normal tissues. tissue_expression_down hsa-mir-124 Glioblastoma 23817964 MiR-124 inhibits the growth of glioblastoma through the downregulation of SOS1. tissue_expression_down hsa-mir-181b "Carcinoma, Lung, Non-Small-Cell" 23827213 Down-regulation of microRNA-181b is a potential prognostic marker of non-small cell lung cancer. tissue_expression_down hsa-mir-19a Breast Neoplasms 23831570 MicroRNA-19a-3p inhibits breast cancer progression and metastasis by inducing macrophage polarization through downregulated expression of Fra-1 proto-oncogene. tissue_expression_down hsa-mir-223 Pancreatic Neoplasms 23834147 Genistein down-regulates miR-223 expression in pancreatic cancer cells. tissue_expression_down hsa-mir-451 Colorectal Carcinoma 23886157 MicroRNA-451 inhibits growth of human colorectal carcinoma cells via downregulation of Pi3k/Akt pathway. tissue_expression_down hsa-mir-21 "Carcinoma, Colon" 23894315 Difluorinated-curcumin (CDF) restores PTEN expression in colon cancer cells by down-regulating miR-21. tissue_expression_down hsa-mir-187 "Carcinoma, Renal Cell, Clear-Cell" 23916610 "MicroRNA-187, down-regulated in clear cell renal cell carcinoma and associated with lower survival, inhibits cell growth and migration though targeting B7-H3." tissue_expression_down hsa-mir-223 "Carcinoma, Hepatocellular" 23925649 MiR-223 modulates multidrug resistance via downregulation of ABCB1 in hepatocellular carcinoma cells. tissue_expression_down hsa-mir-34a Prostate Neoplasms 23936419 Our results indicated that genistein inhibited PCa cell growth through down-regulation of oncogenic HOTAIR that is also targeted by tumor suppressor miR-34a. These findings enhance understanding of how genistein regulates lncRNA HOTAIR and miR-34a in PCa. tissue_expression_down hsa-mir-26b Breast Neoplasms 23939832 MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion. tissue_expression_down hsa-let-7i "Carcinoma, Bladder" 23946872 "Within this group, let-7b and let-7i exhibited decreased expression, while miR-1290 and miR-138 displayed increased expression levels in gemcitabine-resistant cells." tissue_expression_down hsa-mir-218 Medulloblastoma 23970061 miR-218 is downregulated and directly targets SH3GL1 in childhood medulloblastoma. tissue_expression_down hsa-mir-205 Prostate Neoplasms 23974361 miR-205 is frequently downregulated in prostate cancer and acts as a tumor suppressor by inhibiting tumor growth. tissue_expression_down hsa-mir-15 "Leukemia, Lymphocytic, Chronic, B-Cell" 23974981 Defective DROSHA processing contributes to downregulation of MiR-15/-16 in chronic lymphocytic leukemia. tissue_expression_down hsa-mir-16 "Leukemia, Lymphocytic, Chronic, B-Cell" 23974981 Defective DROSHA processing contributes to downregulation of MiR-15/-16 in chronic lymphocytic leukemia. tissue_expression_down hsa-mir-145 Inflammation 23980205 "We demonstrate that miR-145, downregulated by IFN-I,targets histone deacetylase 11 to promote innate IL-10 expression in macrophages.Our findings suggest a new IFN-I-mediated negative feedback loop in the fine-tuning of innate IL-10 production that creates precise coordination of innate immune responses." tissue_expression_down hsa-mir-203 "Carcinoma, Esophageal" 24001611 MiR-203 suppresses tumor growth and invasion and down-regulates MiR-21 expression through repressing Ran in esophageal cancer. tissue_expression_down hsa-mir-21 "Carcinoma, Esophageal" 24001611 MiR-203 suppresses tumor growth and invasion and down-regulates MiR-21 expression through repressing Ran in esophageal cancer. tissue_expression_down hsa-mir-137 Melanoma 24001901 "miR-34a, miR-137 and miR-182 all had lower expression levels in uveal melanoma cell lines, compared with normal cells" tissue_expression_down hsa-mir-182 Melanoma 24001901 "miR-34a, miR-137 and miR-182 all had lower expression levels in uveal melanoma cell lines, compared with normal cells" tissue_expression_down hsa-mir-155 Choriocarcinoma 24007214 There were low expressions of exosomal miR-155 and miR-196a in serum samples of PC patients when U-6 was used as a control. Serum exosomal miR-17-5p was higher in PC patients than in non-PC patients and healthy participants. tissue_expression_down hsa-mir-196a Choriocarcinoma 24007214 There were low expressions of exosomal miR-155 and miR-196a in serum samples of PC patients when U-6 was used as a control. Serum exosomal miR-17-5p was higher in PC patients than in non-PC patients and healthy participants. tissue_expression_down hsa-mir-33a "Carcinoma, Hepatocellular" 24015284 miR-33a down-regulated ¦Â-catenin by directly binding to the 3'-UTR of ¦Â-catenin. These results suggested that AFB1 might down-regulate ¦Â-catenin by up-regulating miR-33a. This understanding opens new lines of thought in the potential role of miR-33a in the clinical therapy of cancer. tissue_expression_down hsa-mir-199a Lung Neoplasms 24022342 downregulation of miR-199a is essential for hypoxia-induced proliferation through derepressing the expression of HIF1a expression and affecting HIF1a mediated glycolytic pathway in NSCLC progression. tissue_expression_down hsa-mir-16 Colorectal Carcinoma 24045965 Down-regulation of miR-16 plays critical roles in CRC progression.Low miR-16 expression is an independent factor predicting a poor prognosis for CRC patients. tissue_expression_down hsa-mir-370 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 24055400 "In conclusion, our results suggest that miR-370 may function as a tumor suppressor in LSCC through downregulation of FoxM1,suggesting that miR-370 could serve as a novel potential maker for LSCC therapy." tissue_expression_down hsa-mir-138 Neoplasms [unspecific] 24057215 MiR-138 downregulates miRNA processing in HeLa cells by targeting RMND5A and decreasing Exportin-5 stability. tissue_expression_down hsa-mir-199a "Carcinoma, Gastric" 24065659 MicroRNA-199a-3p is downregulated in gastric carcinomas and modulates cell proliferation. tissue_expression_down hsa-let-7f "Leukemia, Myeloid, Acute" 24067109 MicroRNA let-7f is down-regulated in patients with refractory acute myeloid leukemia and is involved in chemotherapy resistance of adriamycin-resistant leukemic cells. tissue_expression_down hsa-let-7b Primary Biliary Cirrhosis 24074714 "Decreased expression of miR-let-7b may be associated with development and progression of PBC, and this miRNA may represent a novel target of improved diagnostic and preventive strategies for PBC." tissue_expression_down hsa-mir-27a Intervertebral Disc Degeneration 24086481 This present study revealed that downregulated miR-27a might develop a novel intervention for IDD treatment through the prevention of apoptosis in Nucleus pulposus Cells. tissue_expression_down hsa-mir-487b Cardiovascular Diseases [unspecific] 24096771 "Angiotensin II-induced hypertension leads to upregulation of miR-487b, which targets IRS1. Via downregulation of IRS1, miR-487b can contribute to cell death and loss of adventitial and medial integrity during hypertension-induced vascular pathology." tissue_expression_down hsa-mir-760 Gastric Neoplasms 24097871 "Histone mRNA was upregulated, whereas miR-760 was downregulated in the bone marrow and primary tumor of advanced gastric cancer patients, suggesting that the histone mRNA/miR-760 axis had a crucial role in the development of gastric cancer." tissue_expression_down hsa-mir-30c "Carcinoma, Renal Cell" 24112779 "hypoxia induces EMT in RCC cells through downregulation of miR-30c, which leads to subsequent increase of Slug expression and repression of E-cadherin production, and suggest a potential application of miR-30c in RCC treatment." tissue_expression_down hsa-mir-34a Ischemic Heart Disease 24123326 "miR-34a was downregulated in heat shocked Sca-11 stem cells (HSSca-11 cells),heat shock induces exosomal transfer of HSF1 from Sca-1(+) cells, which directs ischemic cardiomyocytes toward a prosurvival phenotype by epigenetic repression of miR-34a." tissue_expression_down hsa-mir-214 "Carcinoma, Hepatocellular" 24129885 "the upregulation of miR-130b and downregulation of miR-199a-5p, miR-199b-5p, and miR-214 were more significant in HCC cell lines" tissue_expression_down hsa-mir-149 "Carcinoma, Renal Cell" 24137408 "miR-141, miR-149 and miR-429 were downregulated in the ccRCC tissues" tissue_expression_down hsa-mir-29c "Leukemia, Lymphocytic, Chronic, B-Cell" 24138306 down-regulation of miR-29c is associated with higher tumor burden and significantly predicts short survival in Chinese patients with CLL tissue_expression_down hsa-mir-661 Breast Neoplasms 24141721 miR-661 downregulates both Mdm2 and Mdm4 to activate p53. tissue_expression_down hsa-mir-497 Breast Neoplasms 24143964 "downregulation of miR-497 was correlated with BC progression, and miR-497 might be a potential molecular biomarker for predicting the prognosis of patients." tissue_expression_down hsa-mir-25 "Muscular Dystrophy, Facioscapulohumeral" 24145033 "eight were down-regulated (miR-15b, miR-20b, miR-21, miR-25, miR-100, miR-155, miR-345, and miR-594)" tissue_expression_down hsa-mir-370 "Leukemia, Myeloid, Chronic" 24148180 MiR-370 sensitized K562 cells to HHT by inducing apoptosis in part by downregulation of FoxM1 expression. These findings may provide further information for CML treatment with HHT. tissue_expression_down hsa-mir-16 Pleural Mesothelioma 24148817 The miR-15/16 family is downregulated and has tumour suppressor function in MPM. Restoring miR-16 expression represents a novel therapeutic approach for MPM. tissue_expression_down hsa-mir-141 Esophageal Neoplasms 24155113 "The statistical significance of downregulation in hsa-miR-301a, hsa-miR-141 and hsa-miR-18b expression (P??90% of the 991 lung cancer samples" tissue_expression_down hsa-mir-490 Lung Neoplasms 28334118 "we found that hsa-mir-210 was upregulated, while hsa-mir-490 and hsa-mir-486 were downregulated in?>?90% of the 991 lung cancer samples" tissue_expression_down hsa-let-7f Ischemia 28345812 Reduced expression of let-7f activates TGF-¦Â/ALK5 pathway and leads to impaired ischaemia-induced neovascularization after cigarette smoke exposure. tissue_expression_down hsa-mir-197 "Fibromatosis, Aggressive" 28418912 "The correlation between sporadic DTs and miRNA expression showed that miR-21-3p increased in mutated versus wild-type DTs, while miR-197-3p was decreased" tissue_expression_down hsa-mir-29b Breast Neoplasms 28465475 Down-regulation of miR-29b in carcinoma associated fibroblasts promotes cell growth and metastasis of breast cancer. tissue_expression_down hsa-mir-148a "Carcinoma, Gastric" 28475823 Down-regulated miRs specifically correlate with non-cardial gastric cancers and Lauren's classification system. tissue_expression_down hsa-mir-204 "Carcinoma, Gastric" 28475823 Down-regulated miRs specifically correlate with non-cardial gastric cancers and Lauren's classification system. tissue_expression_down hsa-mir-31 "Carcinoma, Gastric" 28475823 Down-regulated miRs specifically correlate with non-cardial gastric cancers and Lauren's classification system. tissue_expression_down hsa-mir-375 "Carcinoma, Gastric" 28475823 Down-regulated miRs specifically correlate with non-cardial gastric cancers and Lauren's classification system. tissue_expression_down hsa-mir-155 Behcet Disease 28482290 "up regulation of miR-182 and miR-3591-3p; down regulation of miR-155, miR-638 and miR-4488 in the pathogenesis of the disease" tissue_expression_down hsa-mir-4488 Behcet Disease 28482290 "up regulation of miR-182 and miR-3591-3p; down regulation of miR-155, miR-638 and miR-4488 in the pathogenesis of the disease" tissue_expression_down hsa-mir-638 Behcet Disease 28482290 "up regulation of miR-182 and miR-3591-3p; down regulation of miR-155, miR-638 and miR-4488 in the pathogenesis of the disease" tissue_expression_down hsa-mir-200b Colon Neoplasms 28552992 MicroRNA-200b is downregulated in colon cancer budding cells. tissue_expression_down hsa-mir-1 Pituitary Neoplasms 28577032 "Studies have shown that the levels of miR-1, miR-195, and miR-206 are downregulated in Pas" tissue_expression_down hsa-mir-195 Pituitary Neoplasms 28577032 "Studies have shown that the levels of miR-1, miR-195, and miR-206 are downregulated in Pas" tissue_expression_down hsa-mir-206 Pituitary Neoplasms 28577032 "Studies have shown that the levels of miR-1, miR-195, and miR-206 are downregulated in Pas" tissue_expression_down hsa-mir-200b Liver Cirrhosis 28634212 Prolonged darkness reduces liver fibrosis in a mouse model of primary sclerosing cholangitis by miR-200b down-regulation. tissue_expression_down hsa-mir-146a Obesity 28652200 Down-regulation of miRNAs in the brain and development of diet-induced obesity tissue_expression_down hsa-mir-155 Obesity 28652200 Down-regulation of miRNAs in the brain and development of diet-induced obesity. tissue_expression_down hsa-mir-451 "Carcinoma, Lung, Non-Small-Cell" 28704499 The low expression of miR-451 predicts a worse prognosis in non-small cell lung cancer cases. tissue_expression_down hsa-mir-122 Stroke 28751928 A Decrease of Brain MicroRNA-122 Level Is an Early Marker of Cerebrovascular Disease in the Stroke-Prone Spontaneously Hypertensive Rat. tissue_expression_down hsa-mir-138 "Squamous Cell Carcinoma, Esophageal" 28759955 Downregulation of miR-138 predicts poor prognosis in patients with esophageal squamous cell carcinoma tissue_expression_down hsa-mir-15 Chronic Kidney Disease 28771472 MicroRNAs in the miR-17 and miR-15 families are downregulated in chronic kidney disease with hypertension. tissue_expression_down hsa-mir-17 Chronic Kidney Disease 28771472 MicroRNAs in the miR-17 and miR-15 families are downregulated in chronic kidney disease with hypertension. tissue_expression_down hsa-mir-190b Vasomotor Rhinitis 28787742 "there was significant overexpression of miR-543, miR-129-5p, and miR-126-3p, and under-expression of miR-2110, miR-449c-5p, miR-449b-5p, miR-190b, and miR-92b-5p." tissue_expression_down hsa-mir-2110 Vasomotor Rhinitis 28787742 "there was significant overexpression of miR-543, miR-129-5p, and miR-126-3p, and under-expression of miR-2110, miR-449c-5p, miR-449b-5p, miR-190b, and miR-92b-5p." tissue_expression_down hsa-mir-449b Vasomotor Rhinitis 28787742 "there was significant overexpression of miR-543, miR-129-5p, and miR-126-3p, and under-expression of miR-2110, miR-449c-5p, miR-449b-5p, miR-190b, and miR-92b-5p." tissue_expression_down hsa-mir-449c Vasomotor Rhinitis 28787742 "there was significant overexpression of miR-543, miR-129-5p, and miR-126-3p, and under-expression of miR-2110, miR-449c-5p, miR-449b-5p, miR-190b, and miR-92b-5p." tissue_expression_down hsa-mir-92b Vasomotor Rhinitis 28787742 "there was significant overexpression of miR-543, miR-129-5p, and miR-126-3p, and under-expression of miR-2110, miR-449c-5p, miR-449b-5p, miR-190b, and miR-92b-5p." tissue_expression_down hsa-mir-17 "Lymphoma, Large B-Cell, Diffuse" 28817403 "PB-DLBCL and DLBCL-GCB-CC also had much higher levels of miR-125a-3p, miR-34-3p, and miR-155-5p, and significantly lower levels of miR-17-5p and miR-17-3p" tissue_expression_down hsa-mir-200b Colon Neoplasms 28821160 "downregulation of AKT, NF-¦ÊB, Bcl-XL expressions and some key oncomicroRNAs such as miRNA-21 and miRNA-200b significantly" tissue_expression_down hsa-mir-21 Colon Neoplasms 28821160 "downregulation of AKT, NF-¦ÊB, Bcl-XL expressions and some key oncomicroRNAs such as miRNA-21 and miRNA-200b significantly" tissue_expression_down hsa-let-7a Lung Neoplasms 28846189 "Let-7a, miR-16 and miR-34a, were found to be significantly downregulated by chronic PM2.5 exposure" tissue_expression_down hsa-mir-16 Lung Neoplasms 28846189 "Let-7a, miR-16 and miR-34a, were found to be significantly downregulated by chronic PM2.5 exposure" tissue_expression_down hsa-mir-34a Lung Neoplasms 28846189 "Let-7a, miR-16 and miR-34a, were found to be significantly downregulated by chronic PM2.5 exposure" tissue_expression_down hsa-mir-148a Colorectal Carcinoma 28863773 Down-regulation of miRNA-148a and miRNA-625-3p in colorectal cancer is associated with tumor budding. tissue_expression_down hsa-mir-625 Colorectal Carcinoma 28863773 Down-regulation of miRNA-148a and miRNA-625-3p in colorectal cancer is associated with tumor budding. tissue_expression_down hsa-mir-221 Prostate Neoplasms 28886115 Androgen receptor-mediated downregulation of microRNA-221 and -222 in castration-resistant prostate cancer. tissue_expression_down hsa-mir-222 Prostate Neoplasms 28886115 Androgen receptor-mediated downregulation of microRNA-221 and -222 in castration-resistant prostate cancer. tissue_expression_down hsa-mir-21 Alcoholic Cardiomyopathy 29039471 "The present study confirmed that H2S relieves myocardial fibrosis in mice with ACM, and the underlying mechanism may involve the downregulation of autophagy and miR-21 and miR-211 expression levels." tissue_expression_down hsa-mir-221 Alcoholic Cardiomyopathy 29039471 "The present study confirmed that H2S relieves myocardial fibrosis in mice with ACM, and the underlying mechanism may involve the downregulation of autophagy and miR-21 and miR-211 expression levels." tissue_expression_down hsa-mir-199a Ovarian Germ Cell Cancer 29138809 "Higher expression of miR-373-3p, miR-372-3p and miR-302c-3p and lower expression of miR-199a-5p, miR-214-5p and miR-202-3p were reproducibly observed in malignant OGCTs as compared to benign OGCTs or SCSTs" tissue_expression_down hsa-mir-202 Ovarian Germ Cell Cancer 29138809 "Higher expression of miR-373-3p, miR-372-3p and miR-302c-3p and lower expression of miR-199a-5p, miR-214-5p and miR-202-3p were reproducibly observed in malignant OGCTs as compared to benign OGCTs or SCSTs" tissue_expression_down hsa-mir-214 Ovarian Germ Cell Cancer 29138809 "Higher expression of miR-373-3p, miR-372-3p and miR-302c-3p and lower expression of miR-199a-5p, miR-214-5p and miR-202-3p were reproducibly observed in malignant OGCTs as compared to benign OGCTs or SCSTs" tissue_expression_down hsa-mir-1 Myocardial Infarction 29162889 "The expression level of miR-143 in monocytes from STEMI patients compared to healthy controls was increased, whereas the expression of miR-1, -92a, -99a, and -223 was reduced significantly" tissue_expression_down hsa-mir-223 Myocardial Infarction 29162889 "The expression level of miR-143 in monocytes from STEMI patients compared to healthy controls was increased, whereas the expression of miR-1, -92a, -99a, and -223 was reduced significantly" tissue_expression_down hsa-mir-92a Myocardial Infarction 29162889 "The expression level of miR-143 in monocytes from STEMI patients compared to healthy controls was increased, whereas the expression of miR-1, -92a, -99a, and -223 was reduced significantly" tissue_expression_down hsa-mir-99a Myocardial Infarction 29162889 "The expression level of miR-143 in monocytes from STEMI patients compared to healthy controls was increased, whereas the expression of miR-1, -92a, -99a, and -223 was reduced significantly" tissue_expression_down hsa-mir-125b Ovarian Neoplasms 29307001 "miR-26a, miR-125b-5p, miR-17-5p and miR-221 downregulation could be related to poor EOC prognosis" tissue_expression_down hsa-mir-17 Ovarian Neoplasms 29307001 "miR-26a, miR-125b-5p, miR-17-5p and miR-221 downregulation could be related to poor EOC prognosis" tissue_expression_down hsa-mir-221 Ovarian Neoplasms 29307001 "miR-26a, miR-125b-5p, miR-17-5p and miR-221 downregulation could be related to poor EOC prognosis" tissue_expression_down hsa-mir-26a Ovarian Neoplasms 29307001 "miR-26a, miR-125b-5p, miR-17-5p and miR-221 downregulation could be related to poor EOC prognosis" tissue_expression_down hsa-let-7a "Carcinoma, Hepatocellular" 29314614 "miR-1, miR-122, let-7a, and let-7g were downregulated, whereas miR-10b and miR-21 were upregulated in canine HCC" tissue_expression_down hsa-let-7g "Carcinoma, Hepatocellular" 29314614 "miR-1, miR-122, let-7a, and let-7g were downregulated, whereas miR-10b and miR-21 were upregulated in canine HCC" tissue_expression_down hsa-mir-1 "Carcinoma, Hepatocellular" 29314614 "miR-1, miR-122, let-7a, and let-7g were downregulated, whereas miR-10b and miR-21 were upregulated in canine HCC" tissue_expression_down hsa-mir-122 "Carcinoma, Hepatocellular" 29314614 "miR-1, miR-122, let-7a, and let-7g were downregulated, whereas miR-10b and miR-21 were upregulated in canine HCC" tissue_expression_down hsa-mir-145 NUT Midline Carcinoma 29322795 "All NMCs showed upregulation of miR-9 and downregulation of miR-99a and miR-145 and two cases featured also upregulation of miR-21, miR-143, and miR-484" tissue_expression_down hsa-mir-99a NUT Midline Carcinoma 29322795 "All NMCs showed upregulation of miR-9 and downregulation of miR-99a and miR-145 and two cases featured also upregulation of miR-21, miR-143, and miR-484" tissue_expression_down hsa-mir-125 Infection [unspecific] 29391047 "upregulated miR-21, miR-155, miR-150, and miR-221, as well as downregulated miR-143 and miR-125, all of them previously linked to other bacterial infections" tissue_expression_down hsa-mir-143 Infection [unspecific] 29391047 "upregulated miR-21, miR-155, miR-150, and miR-221, as well as downregulated miR-143 and miR-125, all of them previously linked to other bacterial infections" tissue_expression_down hsa-let-7i Hepatoblastoma 29404451 "Let-7i-3p, miR-449b-3p, miR-624-5p, and miR-885-5p were decreased in tumors compared to normal livers" tissue_expression_down hsa-mir-449b Hepatoblastoma 29404451 "Let-7i-3p, miR-449b-3p, miR-624-5p, and miR-885-5p were decreased in tumors compared to normal livers" tissue_expression_down hsa-mir-624 Hepatoblastoma 29404451 "Let-7i-3p, miR-449b-3p, miR-624-5p, and miR-885-5p were decreased in tumors compared to normal livers" tissue_expression_down hsa-mir-885 Hepatoblastoma 29404451 "Let-7i-3p, miR-449b-3p, miR-624-5p, and miR-885-5p were decreased in tumors compared to normal livers" tissue_expression_down hsa-mir-129 Infection [unspecific] 29425228 "Seven of the 26 miRNAs, miR-99b-5p, miR-129-3p, miR-188-5p, miR-363-3p, miR-1295a, miR-4443 and miR-6721-5p, showed significantly decreased expression in individuals with detectable oral shedding" tissue_expression_down hsa-mir-1295a Infection [unspecific] 29425228 "Seven of the 26 miRNAs, miR-99b-5p, miR-129-3p, miR-188-5p, miR-363-3p, miR-1295a, miR-4443 and miR-6721-5p, showed significantly decreased expression in individuals with detectable oral shedding" tissue_expression_down hsa-mir-188 Infection [unspecific] 29425228 "Seven of the 26 miRNAs, miR-99b-5p, miR-129-3p, miR-188-5p, miR-363-3p, miR-1295a, miR-4443 and miR-6721-5p, showed significantly decreased expression in individuals with detectable oral shedding" tissue_expression_down hsa-mir-363 Infection [unspecific] 29425228 "Seven of the 26 miRNAs, miR-99b-5p, miR-129-3p, miR-188-5p, miR-363-3p, miR-1295a, miR-4443 and miR-6721-5p, showed significantly decreased expression in individuals with detectable oral shedding" tissue_expression_down hsa-mir-4443 Infection [unspecific] 29425228 "Seven of the 26 miRNAs, miR-99b-5p, miR-129-3p, miR-188-5p, miR-363-3p, miR-1295a, miR-4443 and miR-6721-5p, showed significantly decreased expression in individuals with detectable oral shedding" tissue_expression_down hsa-mir-6721 Infection [unspecific] 29425228 "Seven of the 26 miRNAs, miR-99b-5p, miR-129-3p, miR-188-5p, miR-363-3p, miR-1295a, miR-4443 and miR-6721-5p, showed significantly decreased expression in individuals with detectable oral shedding" tissue_expression_down hsa-mir-99b Infection [unspecific] 29425228 "Seven of the 26 miRNAs, miR-99b-5p, miR-129-3p, miR-188-5p, miR-363-3p, miR-1295a, miR-4443 and miR-6721-5p, showed significantly decreased expression in individuals with detectable oral shedding" tissue_expression_down hsa-mir-192 "Carcinoma, Renal Cell" 29440068 miR-192 and miR-194 as downregulated tissue_expression_down hsa-mir-194 "Carcinoma, Renal Cell" 29440068 miR-192 and miR-194 as downregulated tissue_expression_down hsa-mir-125a "Squamous Cell Carcinoma, Oral" 29480379 increased miR-21 levels in conjunction with decreased miR-125a levels in saliva of OLP patients may be indicative for a poor prognosis tissue_expression_down hsa-mir-34a Cervical Neoplasms 29487007 "MiR-21-5p upregulation, miR-34a downregulation, and hTERC amplification were associated with the aggressive progression of CC, which suggests that miR-21-5p, miR-34a and hTERC might serve as surrogate markers for CC progression and potential molecular targets for blockage of the development of CC" tissue_expression_down hsa-mir-126 Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_down hsa-mir-143 Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_down hsa-mir-145 Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_down hsa-mir-30a Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_down hsa-mir-30d Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_down hsa-mir-451a Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_down hsa-mir-486 Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_down hsa-mir-196b Ovarian Neoplasms 29518404 "Specifically, miR-196b, miR-532, miR-886-3b, and miR-99b exhibited lower levels in HGOSC compared with USC, whereas miR-29c, miR-155, miR-454, miR-146b-5p, miR-486-5p, miR-27a, miR-192, and miR-141 exhibited significantly higher expression in HGOSC samples" tissue_expression_down hsa-mir-532 Ovarian Neoplasms 29518404 "Specifically, miR-196b, miR-532, miR-886-3b, and miR-99b exhibited lower levels in HGOSC compared with USC, whereas miR-29c, miR-155, miR-454, miR-146b-5p, miR-486-5p, miR-27a, miR-192, and miR-141 exhibited significantly higher expression in HGOSC samples" tissue_expression_down hsa-mir-886 Ovarian Neoplasms 29518404 "Specifically, miR-196b, miR-532, miR-886-3b, and miR-99b exhibited lower levels in HGOSC compared with USC, whereas miR-29c, miR-155, miR-454, miR-146b-5p, miR-486-5p, miR-27a, miR-192, and miR-141 exhibited significantly higher expression in HGOSC samples" tissue_expression_down hsa-mir-99b Ovarian Neoplasms 29518404 "Specifically, miR-196b, miR-532, miR-886-3b, and miR-99b exhibited lower levels in HGOSC compared with USC, whereas miR-29c, miR-155, miR-454, miR-146b-5p, miR-486-5p, miR-27a, miR-192, and miR-141 exhibited significantly higher expression in HGOSC samples" tissue_expression_down hsa-mir-101 "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_down hsa-mir-125b "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_down hsa-mir-16 "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_down hsa-mir-17 "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_down hsa-mir-204 "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_down hsa-mir-20a "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_down hsa-mir-32 "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_down hsa-mir-124 Glioblastoma 29559295 "In our microarray data, lower expression of miR-219-5p, miR-124, and miR-128 and higher expression of miR-21 was observed in GBM compared with the peripheral region, similar to the results of previous reports" tissue_expression_down hsa-mir-128 Glioblastoma 29559295 "In our microarray data, lower expression of miR-219-5p, miR-124, and miR-128 and higher expression of miR-21 was observed in GBM compared with the peripheral region, similar to the results of previous reports" tissue_expression_down hsa-mir-219 Glioblastoma 29559295 "In our microarray data, lower expression of miR-219-5p, miR-124, and miR-128 and higher expression of miR-21 was observed in GBM compared with the peripheral region, similar to the results of previous reports" tissue_expression_down hsa-mir-3127 "Carcinoma, Lung, Non-Small-Cell" 29566281 Downregulation of miR-3127-5p promotes epithelial-mesenchymal transition via FZD4 regulation of Wnt/¦Â-catenin signaling in non-small-cell lung cancer. tissue_expression_down hsa-mir-135b Prostate Neoplasms 29568403 "top nine miRNA with significantly lower expression level in ExoHypoxic compared to ExoNormoxic were miR-521, miR-27a, miR-324, miR-579, miR-502, miR-222, miR-135b, miR-146a and miR-491." tissue_expression_down hsa-mir-146a Prostate Neoplasms 29568403 "top nine miRNA with significantly lower expression level in ExoHypoxic compared to ExoNormoxic were miR-521, miR-27a, miR-324, miR-579, miR-502, miR-222, miR-135b, miR-146a and miR-492." tissue_expression_down hsa-mir-222 Prostate Neoplasms 29568403 "top nine miRNA with significantly lower expression level in ExoHypoxic compared to ExoNormoxic were miR-521, miR-27a, miR-324, miR-579, miR-502, miR-222, miR-135b, miR-146a and miR-491." tissue_expression_down hsa-mir-27a Prostate Neoplasms 29568403 "top nine miRNA with significantly lower expression level in ExoHypoxic compared to ExoNormoxic were miR-521, miR-27a, miR-324, miR-579, miR-502, miR-222, miR-135b, miR-146a and miR-491." tissue_expression_down hsa-mir-324 Prostate Neoplasms 29568403 "top nine miRNA with significantly lower expression level in ExoHypoxic compared to ExoNormoxic were miR-521, miR-27a, miR-324, miR-579, miR-502, miR-222, miR-135b, miR-146a and miR-491." tissue_expression_down hsa-mir-491 Prostate Neoplasms 29568403 "top nine miRNA with significantly lower expression level in ExoHypoxic compared to ExoNormoxic were miR-521, miR-27a, miR-324, miR-579, miR-502, miR-222, miR-135b, miR-146a and miR-492." tissue_expression_down hsa-mir-502 Prostate Neoplasms 29568403 "top nine miRNA with significantly lower expression level in ExoHypoxic compared to ExoNormoxic were miR-521, miR-27a, miR-324, miR-579, miR-502, miR-222, miR-135b, miR-146a and miR-491." tissue_expression_down hsa-mir-521 Prostate Neoplasms 29568403 "top nine miRNA with significantly lower expression level in ExoHypoxic compared to ExoNormoxic were miR-521, miR-27a, miR-324, miR-579, miR-502, miR-222, miR-135b, miR-146a and miR-491." tissue_expression_down hsa-mir-579 Prostate Neoplasms 29568403 "top nine miRNA with significantly lower expression level in ExoHypoxic compared to ExoNormoxic were miR-521, miR-27a, miR-324, miR-579, miR-502, miR-222, miR-135b, miR-146a and miR-491." tissue_expression_down hsa-mir-145 "Carcinoma, Endometrioid Endometrial" 29569698 miRNA-145 expression was lower in DPEEOC endometrial tissues and higher in DPEEOC ovarian tissues compared to the corresponding normal tissues tissue_expression_down hsa-mir-143 "Carcinoma, Hepatocellular, HBV-Related" 29616093 "These results indicated that the decreased expression of the miR-143/145 cluster and their host gene MIR143HG in HBV-associated HCC tissue was associated with prognosis, and each of these miRNAs may serve as a valuable diagnostic biomarker for predicting HBV-associated HCC tumorigenesis" tissue_expression_down hsa-mir-145 "Carcinoma, Hepatocellular, HBV-Related" 29616093 "These results indicated that the decreased expression of the miR-143/145 cluster and their host gene MIR143HG in HBV-associated HCC tissue was associated with prognosis, and each of these miRNAs may serve as a valuable diagnostic biomarker for predicting HBV-associated HCC tumorigenesis" tissue_expression_down hsa-mir-145 Urinary System Cancer 29623292 the decline of miR-145 expression level have been proved to be able to distinguish bladder cancer patients from non-cancer controls in cell-free urine samples; the elevation of miR-10a and miR-30d was also observed in urine samples from patients with focal segmental glomerulosclerosis tissue_expression_down hsa-mir-126 Atherosclerosis 29642385 "Moreover, the expression level of miR-126 tended to be downregulated and that of miR-21 tended to be upregulated in ApoE KO mice exposed to the high dose of CS, albeit statistically insignificant" tissue_expression_down hsa-mir-126 Myocardial Infarction 29642385 "Moreover, the expression level of miR-126 tended to be downregulated and that of miR-21 tended to be upregulated in ApoE KO mice exposed to the high dose of CS, albeit statistically insignificant" tissue_expression_down hsa-mir-126 Stroke 29642385 "Moreover, the expression level of miR-126 tended to be downregulated and that of miR-21 tended to be upregulated in ApoE KO mice exposed to the high dose of CS, albeit statistically insignificant" tissue_expression_down hsa-mir-7 Myasthenia Gravis 29655674 miR-7 was the most down-regulated thymic miRNA in MG tissue_expression_down hsa-mir-10a Ependymoma 29658967 low expression of miR-10a and over-expression of miR-10b and miR-29a in ependymoma tissue_expression_down hsa-mir-181c Medulloblastoma 29658967 "Low-expression of miR-221, miR-9, and miR-181c/d and over-expression of miR-101, miR-222, miR-139, miR-1827, and miR-34c was found in medulloblastoma" tissue_expression_down hsa-mir-181d Medulloblastoma 29658967 "Low-expression of miR-221, miR-9, and miR-181c/d and over-expression of miR-101, miR-222, miR-139, miR-1827, and miR-34c was found in medulloblastoma" tissue_expression_down hsa-mir-221 Medulloblastoma 29658967 "Low-expression of miR-221, miR-9, and miR-181c/d and over-expression of miR-101, miR-222, miR-139, miR-1827, and miR-34c was found in medulloblastoma" tissue_expression_down hsa-mir-26a Glioma 29658967 "low expression of miR-26a and overexpression of miR-19a/b, miR-24, miR-27a, miR- 584, and miR-527 in low-grade glioma" tissue_expression_down hsa-mir-9 Medulloblastoma 29658967 "Low-expression of miR-221, miR-9, and miR-181c/d and over-expression of miR-101, miR-222, miR-139, miR-1827, and miR-34c was found in medulloblastoma" tissue_expression_down hsa-mir-203 "Squamous Cell Carcinoma, Head and Neck" 29667275 "miR-26 and miR-125b may be associated with the progression and metastasis of HNSCC, and that miR-203 is associated with a more favourable prognosis." tissue_expression_down hsa-mir-26b "Carcinoma, Breast" 29689244 Decreased expression of microRNA-26b in locally advanced and inflammatory breast cancer. tissue_expression_down hsa-mir-3098 Alcoholic Cardiomyopathy 29734191 The results demonstrated that miR-467d-3p and miR-491-5p were up-regulated and miR-3098-3p was down-regulated in the alcohol-exposed myocardial samples compared with the control samples (P < 0.05). tissue_expression_down hsa-mir-188 "Carcinoma, Cervical" 29737570 the low expression of miR-188 and high expression of miR-223 correlated with the short survival of CC patients tissue_expression_down hsa-mir-197 Chronic Obstructive Pulmonary Disease 29757677 "expression levels of miR-98, miR-139-5p, miR-146b-5p, and miR-451 were upregulated, as compared with NS. In contrast, miR-197, miR-204, miR-485-3p, and miR-627 were downregulated." tissue_expression_down hsa-mir-204 Chronic Obstructive Pulmonary Disease 29757677 "expression levels of miR-98, miR-139-5p, miR-146b-5p, and miR-451 were upregulated, as compared with NS. In contrast, miR-197, miR-204, miR-485-3p, and miR-627 were downregulated." tissue_expression_down hsa-mir-485 Chronic Obstructive Pulmonary Disease 29757677 "expression levels of miR-98, miR-139-5p, miR-146b-5p, and miR-451 were upregulated, as compared with NS. In contrast, miR-197, miR-204, miR-485-3p, and miR-627 were downregulated." tissue_expression_down hsa-mir-627 Chronic Obstructive Pulmonary Disease 29757677 "expression levels of miR-98, miR-139-5p, miR-146b-5p, and miR-451 were upregulated, as compared with NS. In contrast, miR-197, miR-204, miR-485-3p, and miR-627 were downregulated." tissue_expression_down hsa-let-7c "Squamous Cell Carcinoma, Oral" 29764807 "Upregulation of miR-31 and miR-21 and downregulation of miR-99a, let-7c, miR-125b, and miR-100 were found between OSCC and controls" tissue_expression_down hsa-mir-100 "Squamous Cell Carcinoma, Oral" 29764807 "Upregulation of miR-31 and miR-21 and downregulation of miR-99a, let-7c, miR-125b, and miR-100 were found between OSCC and controls" tissue_expression_down hsa-mir-125b "Squamous Cell Carcinoma, Oral" 29764807 "Upregulation of miR-31 and miR-21 and downregulation of miR-99a, let-7c, miR-125b, and miR-100 were found between OSCC and controls" tissue_expression_down hsa-mir-99a "Squamous Cell Carcinoma, Oral" 29764807 "Upregulation of miR-31 and miR-21 and downregulation of miR-99a, let-7c, miR-125b, and miR-100 were found between OSCC and controls" tissue_expression_down hsa-let-7 Gastric Neoplasms 29797599 "Our data showed that miR-146, miR-375, and Let-7 were down-regulated and miR-19 and miR-21 were up-regulated in GC patients with H. pylori infection" tissue_expression_down hsa-mir-146 Gastric Neoplasms 29797599 "Our data showed that miR-146, miR-375, and Let-7 were down-regulated and miR-19 and miR-21 were up-regulated in GC patients with H. pylori infection" tissue_expression_down hsa-mir-375 Gastric Neoplasms 29797599 "Our data showed that miR-146, miR-375, and Let-7 were down-regulated and miR-19 and miR-21 were up-regulated in GC patients with H. pylori infection" tissue_expression_down hsa-mir-200a Chronic Kidney Disease 29909697 "We recognized in both meta-analysis approaches a significant miRNA meta-signature of five up-regulated (miR-142-3p, miR-223-3p, miR-21-5p, miR-142-5p and miR-214-3p) and two down-regulated (miR-29c-3p and miR-200a-3p) miRNAs" tissue_expression_down hsa-mir-29c Chronic Kidney Disease 29909697 "We recognized in both meta-analysis approaches a significant miRNA meta-signature of five up-regulated (miR-142-3p, miR-223-3p, miR-21-5p, miR-142-5p and miR-214-3p) and two down-regulated (miR-29c-3p and miR-200a-3p) miRNAs" tissue_expression_down hsa-mir-141 "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_down hsa-mir-145 "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_down hsa-mir-199a "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_down hsa-mir-200a "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_down hsa-mir-200b "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_down hsa-mir-200c "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_down hsa-mir-429 "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_down hsa-mir-379 Oligodendroglioma 29931616 Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas. tissue_expression_down hsa-mir-656 Oligodendroglioma 29931616 Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas. tissue_expression_down hsa-mir-183 "Adenocarcinoma, Pancreatic Ductal" 29952976 the downregulated miR-183 level might be associated with poor prognosis in patients with melanoma and pancreatic ductal adenocarcinoma tissue_expression_down hsa-mir-183 Melanoma 29952976 the downregulated miR-183 level might be associated with poor prognosis in patients with melanoma and pancreatic ductal adenocarcinoma tissue_expression_down hsa-mir-490 "Carcinoma, Hepatocellular" 30007991 We found that miR-490-3p is down-regulated in HCC and is related to genes that have potential tumoral functions tissue_expression_down hsa-mir-486 "Carcinoma, Thyroid, Papillary" 30015845 Downregulation of miR?486?5p in papillary thyroid carcinoma tissue: A study based on microarray and miRNA sequencing. tissue_expression_down hsa-mir-29a Glioma 30016785 MicroRNA-29a-3p Downregulation Causes Gab1 Upregulation to Promote Glioma Cell Proliferation. tissue_expression_down hsa-mir-187 Ovarian Neoplasms 30035102 low miR-187 and miR-489 expression was associated with poor prognosis tissue_expression_down hsa-mir-489 Ovarian Neoplasms 30035102 low miR-187 and miR-489 expression was associated with poor prognosis tissue_expression_down hsa-mir-204 Hepatitis B Virus Infection 30042818 "miR-204, strongly decreased both HBV DNA and HBsAg in culture supernatant of HepG2-hNTCP-C4 cells" tissue_expression_down hsa-mir-128 Cholangiocarcinoma 30042823 "High miR-126, low miR-128 and TEMs were independent prognostic factors for recurrence-free and overall survival" tissue_expression_down hsa-mir-126 Ovarian Neoplasms 30107086 "We report that miR-21 (P?=?0.0001), miR-100 (P?=?0.034), miR-200b (P?=?0.008), and miR-320 (P?=?0.034) are significantly enriched, whereas miR-16 (P?=?0.009), miR-93 (P?=?0.014), miR-126 (P?=?0.012), and miR-223 (P?=?0.029) are underrepresented in exosomes from plasma of EOC patients as compared to those of healthy women. The levels of exosomal miR-23a (P?=?0.009, 0.008) and miR-92a (P?=?009, 0.034) were lower in ovarian cystadenoma patients than in EOC patients and healthy women, respectively" tissue_expression_down hsa-mir-16 Ovarian Neoplasms 30107086 "We report that miR-21 (P?=?0.0001), miR-100 (P?=?0.034), miR-200b (P?=?0.008), and miR-320 (P?=?0.034) are significantly enriched, whereas miR-16 (P?=?0.009), miR-93 (P?=?0.014), miR-126 (P?=?0.012), and miR-223 (P?=?0.029) are underrepresented in exosomes from plasma of EOC patients as compared to those of healthy women. The levels of exosomal miR-23a (P?=?0.009, 0.008) and miR-92a (P?=?009, 0.034) were lower in ovarian cystadenoma patients than in EOC patients and healthy women, respectively" tissue_expression_down hsa-mir-223 Ovarian Neoplasms 30107086 "We report that miR-21 (P?=?0.0001), miR-100 (P?=?0.034), miR-200b (P?=?0.008), and miR-320 (P?=?0.034) are significantly enriched, whereas miR-16 (P?=?0.009), miR-93 (P?=?0.014), miR-126 (P?=?0.012), and miR-223 (P?=?0.029) are underrepresented in exosomes from plasma of EOC patients as compared to those of healthy women. The levels of exosomal miR-23a (P?=?0.009, 0.008) and miR-92a (P?=?009, 0.034) were lower in ovarian cystadenoma patients than in EOC patients and healthy women, respectively" tissue_expression_down hsa-mir-23a Ovarian Neoplasms 30107086 "We report that miR-21 (P?=?0.0001), miR-100 (P?=?0.034), miR-200b (P?=?0.008), and miR-320 (P?=?0.034) are significantly enriched, whereas miR-16 (P?=?0.009), miR-93 (P?=?0.014), miR-126 (P?=?0.012), and miR-223 (P?=?0.029) are underrepresented in exosomes from plasma of EOC patients as compared to those of healthy women. The levels of exosomal miR-23a (P?=?0.009, 0.008) and miR-92a (P?=?009, 0.034) were lower in ovarian cystadenoma patients than in EOC patients and healthy women, respectively" tissue_expression_down hsa-mir-92a Ovarian Neoplasms 30107086 "We report that miR-21 (P?=?0.0001), miR-100 (P?=?0.034), miR-200b (P?=?0.008), and miR-320 (P?=?0.034) are significantly enriched, whereas miR-16 (P?=?0.009), miR-93 (P?=?0.014), miR-126 (P?=?0.012), and miR-223 (P?=?0.029) are underrepresented in exosomes from plasma of EOC patients as compared to those of healthy women. The levels of exosomal miR-23a (P?=?0.009, 0.008) and miR-92a (P?=?009, 0.034) were lower in ovarian cystadenoma patients than in EOC patients and healthy women, respectively" tissue_expression_down hsa-mir-93 Ovarian Neoplasms 30107086 "We report that miR-21 (P?=?0.0001), miR-100 (P?=?0.034), miR-200b (P?=?0.008), and miR-320 (P?=?0.034) are significantly enriched, whereas miR-16 (P?=?0.009), miR-93 (P?=?0.014), miR-126 (P?=?0.012), and miR-223 (P?=?0.029) are underrepresented in exosomes from plasma of EOC patients as compared to those of healthy women. The levels of exosomal miR-23a (P?=?0.009, 0.008) and miR-92a (P?=?009, 0.034) were lower in ovarian cystadenoma patients than in EOC patients and healthy women, respectively" tissue_expression_down hsa-mir-1297 Colon Neoplasms 30127618 "seven miRNAs (hsa-miR-920, hsa-miR-636, hsa-miR-766-3p, hsa-miR-545-5p, hsa-miR-195-3p, hsa-miR-125a-3p, and hsa-miR-196b-3p) were found to be upregulated and six miRNAs (hsa-miR-3613-3p, hsa-miR-29b-3p, hsa-miR-1297, hsa-miR-141-5p, hsa-miR-200c-3p, and hsa-miR-141-3p) were found to be downregulated" tissue_expression_down hsa-mir-141 Colon Neoplasms 30127618 "seven miRNAs (hsa-miR-920, hsa-miR-636, hsa-miR-766-3p, hsa-miR-545-5p, hsa-miR-195-3p, hsa-miR-125a-3p, and hsa-miR-196b-3p) were found to be upregulated and six miRNAs (hsa-miR-3613-3p, hsa-miR-29b-3p, hsa-miR-1297, hsa-miR-141-5p, hsa-miR-200c-3p, and hsa-miR-141-3p) were found to be downregulated" tissue_expression_down hsa-mir-200c Colon Neoplasms 30127618 "seven miRNAs (hsa-miR-920, hsa-miR-636, hsa-miR-766-3p, hsa-miR-545-5p, hsa-miR-195-3p, hsa-miR-125a-3p, and hsa-miR-196b-3p) were found to be upregulated and six miRNAs (hsa-miR-3613-3p, hsa-miR-29b-3p, hsa-miR-1297, hsa-miR-141-5p, hsa-miR-200c-3p, and hsa-miR-141-3p) were found to be downregulated" tissue_expression_down hsa-mir-29b Colon Neoplasms 30127618 "seven miRNAs (hsa-miR-920, hsa-miR-636, hsa-miR-766-3p, hsa-miR-545-5p, hsa-miR-195-3p, hsa-miR-125a-3p, and hsa-miR-196b-3p) were found to be upregulated and six miRNAs (hsa-miR-3613-3p, hsa-miR-29b-3p, hsa-miR-1297, hsa-miR-141-5p, hsa-miR-200c-3p, and hsa-miR-141-3p) were found to be downregulated" tissue_expression_down hsa-mir-3613 Colon Neoplasms 30127618 "seven miRNAs (hsa-miR-920, hsa-miR-636, hsa-miR-766-3p, hsa-miR-545-5p, hsa-miR-195-3p, hsa-miR-125a-3p, and hsa-miR-196b-3p) were found to be upregulated and six miRNAs (hsa-miR-3613-3p, hsa-miR-29b-3p, hsa-miR-1297, hsa-miR-141-5p, hsa-miR-200c-3p, and hsa-miR-141-3p) were found to be downregulated" tissue_expression_down hsa-mir-197 Uterine Leiomyoma 30149651 "The relative expression level of miR-15b was upregulated, and the relative expression levels of miR-29a, -29b, -29c, -197, and -200c were downregulated in UL cells compared to those in UM cells" tissue_expression_down hsa-mir-200c Uterine Leiomyoma 30149651 "The relative expression level of miR-15b was upregulated, and the relative expression levels of miR-29a, -29b, -29c, -197, and -200c were downregulated in UL cells compared to those in UM cells" tissue_expression_down hsa-mir-29a Uterine Leiomyoma 30149651 "The relative expression level of miR-15b was upregulated, and the relative expression levels of miR-29a, -29b, -29c, -197, and -200c were downregulated in UL cells compared to those in UM cells" tissue_expression_down hsa-mir-29b Uterine Leiomyoma 30149651 "The relative expression level of miR-15b was upregulated, and the relative expression levels of miR-29a, -29b, -29c, -197, and -200c were downregulated in UL cells compared to those in UM cells" tissue_expression_down hsa-mir-29c Uterine Leiomyoma 30149651 "The relative expression level of miR-15b was upregulated, and the relative expression levels of miR-29a, -29b, -29c, -197, and -200c were downregulated in UL cells compared to those in UM cells" tissue_expression_down hsa-mir-199a Cholangiocarcinoma 30165035 "the hsa-miR-205-5p and miR-200 family members were markedly up-regulated for 600-1500 folds, whereas the miR-199 family members and their clustered miRNA, hsa-miR-214-3p, were down-regulated for 1000-2000 folds" tissue_expression_down hsa-mir-199b Cholangiocarcinoma 30165035 "the hsa-miR-205-5p and miR-200 family members were markedly up-regulated for 600-1500 folds, whereas the miR-199 family members and their clustered miRNA, hsa-miR-214-3p, were down-regulated for 1000-2000 folds" tissue_expression_down hsa-mir-214 Cholangiocarcinoma 30165035 "the hsa-miR-205-5p and miR-200 family members were markedly up-regulated for 600-1500 folds, whereas the miR-199 family members and their clustered miRNA, hsa-miR-214-3p, were down-regulated for 1000-2000 folds" tissue_expression_down hsa-mir-124 Gastric Neoplasms 30171475 "The clinical significance of miR-335, miR-124, miR-218 and miR-484 downregulation in gastric cancer." tissue_expression_down hsa-mir-218 Gastric Neoplasms 30171475 "The clinical significance of miR-335, miR-124, miR-218 and miR-484 downregulation in gastric cancer." tissue_expression_down hsa-mir-335 Gastric Neoplasms 30171475 "The clinical significance of miR-335, miR-124, miR-218 and miR-484 downregulation in gastric cancer." tissue_expression_down hsa-mir-484 Gastric Neoplasms 30171475 "The clinical significance of miR-335, miR-124, miR-218 and miR-484 downregulation in gastric cancer." tissue_expression_down hsa-mir-548c Colorectal Carcinoma 30171732 Downregulation of exosome-encapsulated miR-548c-5p is associated with poor prognosis in colorectal cancer. tissue_expression_down hsa-mir-192 Irritable Bowel Syndrome 30187701 MiRNAs play a pivotal role in visceral hypersensitivity and might be targets in the treatment of IBS by Tongxieyaofang tissue_expression_down hsa-mir-221 Irritable Bowel Syndrome 30187701 MiRNAs play a pivotal role in visceral hypersensitivity and might be targets in the treatment of IBS by Tongxieyaofang tissue_expression_down hsa-mir-223 Irritable Bowel Syndrome 30187701 MiRNAs play a pivotal role in visceral hypersensitivity and might be targets in the treatment of IBS by Tongxieyaofang tissue_expression_down hsa-mir-24 Irritable Bowel Syndrome 30187701 MiRNAs play a pivotal role in visceral hypersensitivity and might be targets in the treatment of IBS by Tongxieyaofang tissue_expression_down hsa-mir-31a Irritable Bowel Syndrome 30187701 MiRNAs play a pivotal role in visceral hypersensitivity and might be targets in the treatment of IBS by Tongxieyaofang tissue_expression_down hsa-let-7b Carcinosarcoma 30200635 "In carcinosarcoma (CS), lower CSS was associated with the upregulation of miR-184, and the downregulation of let-7b-5p and miR-124" tissue_expression_down hsa-let-7f Endometrial Stromal Sarcoma 30200635 "In endometrial stromal sarcomas (ESS), the upregulation of miR-373-3p, miR-372-3p, and let-7b-5p, and the down-expression of let-7f-5p, miR-23-3p, and let-7b-5p were associated with lower CSS" tissue_expression_down hsa-mir-10a Leiomyosarcoma 30200635 "In leiomyosarcoma (LMS), there was an association of lower cancer-specific survival (CSS) with the downregulation of miR-125a-5p and miR-10a-5p, and the upregulation of miR-196a-5p and miR-34c-5p" tissue_expression_down hsa-mir-124 Carcinosarcoma 30200635 "In carcinosarcoma (CS), lower CSS was associated with the upregulation of miR-184, and the downregulation of let-7b-5p and miR-124" tissue_expression_down hsa-mir-125a Leiomyosarcoma 30200635 "In leiomyosarcoma (LMS), there was an association of lower cancer-specific survival (CSS) with the downregulation of miR-125a-5p and miR-10a-5p, and the upregulation of miR-196a-5p and miR-34c-5p" tissue_expression_down hsa-mir-23 Endometrial Stromal Sarcoma 30200635 "In endometrial stromal sarcomas (ESS), the upregulation of miR-373-3p, miR-372-3p, and let-7b-5p, and the down-expression of let-7f-5p, miR-23-3p, and let-7b-5p were associated with lower CSS" tissue_expression_down hsa-let-7a Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-let-7d Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-let-7f Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-let-7g Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-let-7i Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-103a Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-106b Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-128 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-130a Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-130b Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-144 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-148a Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-148b Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-151a Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-151b Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-15a Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-15b Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-16 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-182 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-183 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-186 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-22 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-221 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-223 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-23a Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-26a Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-26b Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-27b Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-28 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-30b Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-30c Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-342 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-425 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-451a Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-532 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-550a Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-584 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-93 Amyotrophic Lateral Sclerosis 30210287 Results showed that 38 miRNAs were significantly downregulated in sALS tissue_expression_down hsa-mir-138 Thyroid Neoplasms 30210669 "We ultimately included five datasets, and further analyzed the four miRNAs that were down-regulated in at least four datasets (miR-7-2-3p, miR-138-5p, miR-144-5p, miR-486-5p)" tissue_expression_down hsa-mir-144 Thyroid Neoplasms 30210669 "We ultimately included five datasets, and further analyzed the four miRNAs that were down-regulated in at least four datasets (miR-7-2-3p, miR-138-5p, miR-144-5p, miR-486-5p)" tissue_expression_down hsa-mir-486 Thyroid Neoplasms 30210669 "We ultimately included five datasets, and further analyzed the four miRNAs that were down-regulated in at least four datasets (miR-7-2-3p, miR-138-5p, miR-144-5p, miR-486-5p)" tissue_expression_down hsa-mir-7-2 Thyroid Neoplasms 30210669 "We ultimately included five datasets, and further analyzed the four miRNAs that were down-regulated in at least four datasets (miR-7-2-3p, miR-138-5p, miR-144-5p, miR-486-5p)" tissue_expression_down hsa-mir-129 "Squamous Cell Carcinoma, Oral" 30210912 "The expression levels of miR-129-5p and miR-296-5p were significantly downregulated in OLK-OSCC tissues compared to OLK tissues, while miR-450b-5p levels were higher in OLK-OSCC tissues" tissue_expression_down hsa-mir-296 "Squamous Cell Carcinoma, Oral" 30210912 "The expression levels of miR-129-5p and miR-296-5p were significantly downregulated in OLK-OSCC tissues compared to OLK tissues, while miR-450b-5p levels were higher in OLK-OSCC tissues" tissue_expression_down hsa-mir-652 Neoplasms [unspecific] 30225717 "Bioinformatic analysis has detected microRNA potentially regulated by xenosensor receptors AhR (miR-28, miR-30c, miR-30e, miR-139, and miR-153) and CAR (miR-29c, miR-31, miR-185, miR-625, and miR-652)" tissue_expression_down hsa-mir-1294 Gastric Neoplasms 30229824 Expression of miR-1294 is downregulated and predicts a poor prognosis in gastric cancer. tissue_expression_down hsa-mir-543 Infertility 30231774 Endometrial miR-543 Is Downregulated During the Implantation Window in Women With Endometriosis-Related Infertility. tissue_expression_down hsa-mir-10b "Carcinoma, Breast" 30250531 3 miRNAs were upregulated: Hsa-miR-21b; hsa-miR-29b; and hsa-miR-155; and 3 miRNAs were downregulated: Hsa-miR-10b; hsa-miR-125; and hsa-miR-145 tissue_expression_down hsa-mir-125 "Carcinoma, Breast" 30250531 3 miRNAs were upregulated: Hsa-miR-21b; hsa-miR-29b; and hsa-miR-155; and 3 miRNAs were downregulated: Hsa-miR-10b; hsa-miR-125; and hsa-miR-145 tissue_expression_down hsa-mir-145 "Carcinoma, Breast" 30250531 3 miRNAs were upregulated: Hsa-miR-21b; hsa-miR-29b; and hsa-miR-155; and 3 miRNAs were downregulated: Hsa-miR-10b; hsa-miR-125; and hsa-miR-145 tissue_expression_down hsa-mir-10a "Carcinoma, Hepatocellular" 30254459 the expression of miR-10a-5p is downregulated and miR-484 is the most abundant miRNA in hepatic precancerous lesions tissue_expression_down hsa-mir-145 "Carcinoma, Hepatocellular" 30272372 "The high?level expression of IGF2 mRNA and cyclin E1 mRNA was due to the low?level expression of hsa?miR?145?5p, hsa?miR?181a?5p, hsa?miR?199a?5p and hsa?miR?223a?3p, and hsa?miR?26a?5p and hsa?miR?26b?5p, respectively" tissue_expression_down hsa-mir-181a "Carcinoma, Hepatocellular" 30272372 "The high?level expression of IGF2 mRNA and cyclin E1 mRNA was due to the low?level expression of hsa?miR?145?5p, hsa?miR?181a?5p, hsa?miR?199a?5p and hsa?miR?223a?3p, and hsa?miR?26a?5p and hsa?miR?26b?5p, respectively" tissue_expression_down hsa-mir-199a "Carcinoma, Hepatocellular" 30272372 "The high?level expression of IGF2 mRNA and cyclin E1 mRNA was due to the low?level expression of hsa?miR?145?5p, hsa?miR?181a?5p, hsa?miR?199a?5p and hsa?miR?223a?3p, and hsa?miR?26a?5p and hsa?miR?26b?5p, respectively" tissue_expression_down hsa-mir-223a "Carcinoma, Hepatocellular" 30272372 "The high?level expression of IGF2 mRNA and cyclin E1 mRNA was due to the low?level expression of hsa?miR?145?5p, hsa?miR?181a?5p, hsa?miR?199a?5p and hsa?miR?223a?3p, and hsa?miR?26a?5p and hsa?miR?26b?5p, respectively" tissue_expression_down hsa-mir-26a "Carcinoma, Hepatocellular" 30272372 "The high?level expression of IGF2 mRNA and cyclin E1 mRNA was due to the low?level expression of hsa?miR?145?5p, hsa?miR?181a?5p, hsa?miR?199a?5p and hsa?miR?223a?3p, and hsa?miR?26a?5p and hsa?miR?26b?5p, respectively" tissue_expression_down hsa-mir-26b "Carcinoma, Hepatocellular" 30272372 "The high?level expression of IGF2 mRNA and cyclin E1 mRNA was due to the low?level expression of hsa?miR?145?5p, hsa?miR?181a?5p, hsa?miR?199a?5p and hsa?miR?223a?3p, and hsa?miR?26a?5p and hsa?miR?26b?5p, respectively" tissue_expression_down hsa-mir-221 "Carcinoma, Pancreatic" 30333874 "The results revealed that 2 upregulated miRNAs (miR-34a and -193a-3p) and 4 downregulated miRNAs (miR-221, -222, -484, and -502-3p) exhibited a consistent expression pattern between the PC-1.0/PC-1 and AsPC-1/CAPAN-2 pancreatic cancer cells" tissue_expression_down hsa-mir-222 "Carcinoma, Pancreatic" 30333874 "The results revealed that 2 upregulated miRNAs (miR-34a and -193a-3p) and 4 downregulated miRNAs (miR-221, -222, -484, and -502-3p) exhibited a consistent expression pattern between the PC-1.0/PC-1 and AsPC-1/CAPAN-2 pancreatic cancer cells" tissue_expression_down hsa-mir-484 "Carcinoma, Pancreatic" 30333874 "The results revealed that 2 upregulated miRNAs (miR-34a and -193a-3p) and 4 downregulated miRNAs (miR-221, -222, -484, and -502-3p) exhibited a consistent expression pattern between the PC-1.0/PC-1 and AsPC-1/CAPAN-2 pancreatic cancer cells" tissue_expression_down hsa-mir-502 "Carcinoma, Pancreatic" 30333874 "The results revealed that 2 upregulated miRNAs (miR-34a and -193a-3p) and 4 downregulated miRNAs (miR-221, -222, -484, and -502-3p) exhibited a consistent expression pattern between the PC-1.0/PC-1 and AsPC-1/CAPAN-2 pancreatic cancer cells" tissue_expression_down hsa-mir-138 "Carcinoma, Renal Cell" 30344735 "2 upregulated (hsa-miR-155-5p and hsa-miR-210-5p) and 6 downregulated (hsa-miR-138-5p, hsa-miR-141-5p, hsa-miR-200c-5p, hsa-miR-362-5p, hsa-miR-363-5p and hsa-miR-429) meta-signature miRNAs in renal carcinoma were identified" tissue_expression_down hsa-mir-141 "Carcinoma, Renal Cell" 30344735 "2 upregulated (hsa-miR-155-5p and hsa-miR-210-5p) and 6 downregulated (hsa-miR-138-5p, hsa-miR-141-5p, hsa-miR-200c-5p, hsa-miR-362-5p, hsa-miR-363-5p and hsa-miR-429) meta-signature miRNAs in renal carcinoma were identified" tissue_expression_down hsa-mir-200c "Carcinoma, Renal Cell" 30344735 "2 upregulated (hsa-miR-155-5p and hsa-miR-210-5p) and 6 downregulated (hsa-miR-138-5p, hsa-miR-141-5p, hsa-miR-200c-5p, hsa-miR-362-5p, hsa-miR-363-5p and hsa-miR-429) meta-signature miRNAs in renal carcinoma were identified" tissue_expression_down hsa-mir-362 "Carcinoma, Renal Cell" 30344735 "2 upregulated (hsa-miR-155-5p and hsa-miR-210-5p) and 6 downregulated (hsa-miR-138-5p, hsa-miR-141-5p, hsa-miR-200c-5p, hsa-miR-362-5p, hsa-miR-363-5p and hsa-miR-429) meta-signature miRNAs in renal carcinoma were identified" tissue_expression_down hsa-mir-363 "Carcinoma, Renal Cell" 30344735 "2 upregulated (hsa-miR-155-5p and hsa-miR-210-5p) and 6 downregulated (hsa-miR-138-5p, hsa-miR-141-5p, hsa-miR-200c-5p, hsa-miR-362-5p, hsa-miR-363-5p and hsa-miR-429) meta-signature miRNAs in renal carcinoma were identified" tissue_expression_down hsa-mir-429 "Carcinoma, Renal Cell" 30344735 "2 upregulated (hsa-miR-155-5p and hsa-miR-210-5p) and 6 downregulated (hsa-miR-138-5p, hsa-miR-141-5p, hsa-miR-200c-5p, hsa-miR-362-5p, hsa-miR-363-5p and hsa-miR-429) meta-signature miRNAs in renal carcinoma were identified" tissue_expression_down hsa-mir-30a Idiopathic Pulmonary Fibrosis 30365083 Downregulation of microRNA?30a in bronchoalveolar lavage fluid from idiopathic pulmonary fibrosis patients. tissue_expression_down hsa-mir-200b Human Cytomegalovirus Infection 30366960 Low tissue levels of 200b-3p and 200c-3p in humans are associated with cytopathic inflammation due to HCMV infection tissue_expression_down hsa-mir-200c Human Cytomegalovirus Infection 30366960 Low tissue levels of 200b-3p and 200c-3p in humans are associated with cytopathic inflammation due to HCMV infection tissue_expression_down hsa-mir-1299 Rhinosinusitis 30378273 "Five upregulated miRNAs, including miR-210-5p, miR-3178, miR-585-3p, miR-3146, and miR-320e, and 19 downregulated miRNAs, including miR-32-3p, miR-1299, miR-3196, miR-3924, and miR-548e-3p, were differentially expressed (p < 0.05, fold change >2) in tissues of CRSwNP vs controls" tissue_expression_down hsa-mir-3196 Rhinosinusitis 30378273 "Five upregulated miRNAs, including miR-210-5p, miR-3178, miR-585-3p, miR-3146, and miR-320e, and 19 downregulated miRNAs, including miR-32-3p, miR-1299, miR-3196, miR-3924, and miR-548e-3p, were differentially expressed (p < 0.05, fold change >2) in tissues of CRSwNP vs controls" tissue_expression_down hsa-mir-32 Rhinosinusitis 30378273 "Five upregulated miRNAs, including miR-210-5p, miR-3178, miR-585-3p, miR-3146, and miR-320e, and 19 downregulated miRNAs, including miR-32-3p, miR-1299, miR-3196, miR-3924, and miR-548e-3p, were differentially expressed (p < 0.05, fold change >2) in tissues of CRSwNP vs controls" tissue_expression_down hsa-mir-3924 Rhinosinusitis 30378273 "Five upregulated miRNAs, including miR-210-5p, miR-3178, miR-585-3p, miR-3146, and miR-320e, and 19 downregulated miRNAs, including miR-32-3p, miR-1299, miR-3196, miR-3924, and miR-548e-3p, were differentially expressed (p < 0.05, fold change >2) in tissues of CRSwNP vs controls" tissue_expression_down hsa-mir-548e Rhinosinusitis 30378273 "Five upregulated miRNAs, including miR-210-5p, miR-3178, miR-585-3p, miR-3146, and miR-320e, and 19 downregulated miRNAs, including miR-32-3p, miR-1299, miR-3196, miR-3924, and miR-548e-3p, were differentially expressed (p < 0.05, fold change >2) in tissues of CRSwNP vs controls" tissue_expression_down hsa-let-7c Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis(down). tissue_expression_down hsa-mir-1-2 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis(down). tissue_expression_down hsa-mir-1247 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis(down). tissue_expression_down hsa-mir-133a-1 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis(down). tissue_expression_down hsa-mir-133a-2 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis(down). tissue_expression_down hsa-mir-133b Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis(down). tissue_expression_down hsa-mir-139 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis(down). tissue_expression_down hsa-mir-145 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis(down). tissue_expression_down hsa-mir-195 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis(down). tissue_expression_down hsa-mir-204 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis(down). tissue_expression_down hsa-mir-206 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis(down). tissue_expression_down hsa-mir-99a Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis(down). tissue_expression_ns hsa-mir-155 "Lymphoma, Burkitt" 16235244 Expression of BIC and miR-155 in 3 latency type III EBV-positive BL cell lines and in all primary PTLD cases suggests a possible role for EBV latency type III specific proteins in the induction of BIC expression. tissue_expression_ns hsa-mir-133b "Carcinoma, Rectal" 16854228 "The analysis by several bioinformatics algorithms of colorectal tumours and adjacent non-neoplastic tissues from patients and colorectal cancer cell lines allowed identifying a group of 13 miRNA whose expression is significantly altered in this tumor. The most significantly deregulated miRNA being miR-31, miR-96, miR-133b, miR-135b, miR-145, and miR-183." tissue_expression_ns hsa-mir-135b "Carcinoma, Rectal" 16854228 "The analysis by several bioinformatics algorithms of colorectal tumours and adjacent non-neoplastic tissues from patients and colorectal cancer cell lines allowed identifying a group of 13 miRNA whose expression is significantly altered in this tumor. The most significantly deregulated miRNA being miR-31, miR-96, miR-133b, miR-135b, miR-145, and miR-183." tissue_expression_ns hsa-mir-145 "Carcinoma, Rectal" 16854228 "The analysis by several bioinformatics algorithms of colorectal tumours and adjacent non-neoplastic tissues from patients and colorectal cancer cell lines allowed identifying a group of 13 miRNA whose expression is significantly altered in this tumor. The most significantly deregulated miRNA being miR-31, miR-96, miR-133b, miR-135b, miR-145, and miR-183." tissue_expression_ns hsa-mir-183 "Carcinoma, Rectal" 16854228 "The analysis by several bioinformatics algorithms of colorectal tumours and adjacent non-neoplastic tissues from patients and colorectal cancer cell lines allowed identifying a group of 13 miRNA whose expression is significantly altered in this tumor. The most significantly deregulated miRNA being miR-31, miR-96, miR-133b, miR-135b, miR-145, and miR-183." tissue_expression_ns hsa-mir-31 "Carcinoma, Rectal" 16854228 "The analysis by several bioinformatics algorithms of colorectal tumours and adjacent non-neoplastic tissues from patients and colorectal cancer cell lines allowed identifying a group of 13 miRNA whose expression is significantly altered in this tumor. The most significantly deregulated miRNA being miR-31, miR-96, miR-133b, miR-135b, miR-145, and miR-183." tissue_expression_ns hsa-mir-96 "Carcinoma, Rectal" 16854228 "The analysis by several bioinformatics algorithms of colorectal tumours and adjacent non-neoplastic tissues from patients and colorectal cancer cell lines allowed identifying a group of 13 miRNA whose expression is significantly altered in this tumor. The most significantly deregulated miRNA being miR-31, miR-96, miR-133b, miR-135b, miR-145, and miR-183." tissue_expression_ns hsa-mir-146a Inflammation 16885212 Analysis of miR-146a and miR-146b gene expression unveiled a pattern of induction in response to a variety of microbial components and proinflammatory cytokines. tissue_expression_ns hsa-mir-146b Inflammation 16885212 Analysis of miR-146a and miR-146b gene expression unveiled a pattern of induction in response to a variety of microbial components and proinflammatory cytokines. tissue_expression_ns hsa-mir-103 Pancreatic Neoplasms 16966691 "the expression of miR-103 and miR-107, associated with lack of expression of miR-155, discriminates tumors from normal" tissue_expression_ns hsa-mir-107 Pancreatic Neoplasms 16966691 "the expression of miR-103 and miR-107, associated with lack of expression of miR-155, discriminates tumors from normal" tissue_expression_ns hsa-mir-155 Pancreatic Neoplasms 16966691 "the expression of miR-103 and miR-107, associated with lack of expression of miR-155, discriminates tumors from normal" tissue_expression_ns hsa-mir-372 "Carcinoma, Embryonal" 17011485 "Expression of miR-372 and miR-373 seems to be specifically associated with germ cell tumors, as most somatic tumors do not express these miRNAs." tissue_expression_ns hsa-mir-373 "Carcinoma, Embryonal" 17011485 "Expression of miR-372 and miR-373 seems to be specifically associated with germ cell tumors, as most somatic tumors do not express these miRNAs." tissue_expression_ns hsa-mir-155 Pancreatic Neoplasms 17149698 "One hundred microRNA precursors were aberrantly expressed in pancreatic cancer or desmoplasia (p < 0.01), including microRNAs previously reported as differentially expressed in other human cancers (miR-155, miR-21, miR-221 and miR-222) as well as those not previously reported in cancer (miR-376a and miR-301)." tissue_expression_ns hsa-mir-21 Pancreatic Neoplasms 17149698 "One hundred microRNA precursors were aberrantly expressed in pancreatic cancer or desmoplasia (p < 0.01), including microRNAs previously reported as differentially expressed in other human cancers (miR-155, miR-21, miR-221 and miR-222) as well as those not previously reported in cancer (miR-376a and miR-301)." tissue_expression_ns hsa-mir-221 Pancreatic Neoplasms 17149698 "One hundred microRNA precursors were aberrantly expressed in pancreatic cancer or desmoplasia (p < 0.01), including microRNAs previously reported as differentially expressed in other human cancers (miR-155, miR-21, miR-221 and miR-222) as well as those not previously reported in cancer (miR-376a and miR-301)." tissue_expression_ns hsa-mir-222 Pancreatic Neoplasms 17149698 "One hundred microRNA precursors were aberrantly expressed in pancreatic cancer or desmoplasia (p < 0.01), including microRNAs previously reported as differentially expressed in other human cancers (miR-155, miR-21, miR-221 and miR-222) as well as those not previously reported in cancer (miR-376a and miR-301)." tissue_expression_ns hsa-mir-301 Pancreatic Neoplasms 17149698 "One hundred microRNA precursors were aberrantly expressed in pancreatic cancer or desmoplasia (p < 0.01), including microRNAs previously reported as differentially expressed in other human cancers (miR-155, miR-21, miR-221 and miR-222) as well as those not previously reported in cancer (miR-376a and miR-301)." tissue_expression_ns hsa-mir-376a Pancreatic Neoplasms 17149698 "One hundred microRNA precursors were aberrantly expressed in pancreatic cancer or desmoplasia (p < 0.01), including microRNAs previously reported as differentially expressed in other human cancers (miR-155, miR-21, miR-221 and miR-222) as well as those not previously reported in cancer (miR-376a and miR-301)." tissue_expression_ns hsa-mir-216 "Adenocarcinoma, Pancreatic Ductal" 17237814 The expression of miR-216 and -217 and lack of expression of miR-133a were identified as characteristic of pancreas tissue. tissue_expression_ns hsa-mir-217 "Adenocarcinoma, Pancreatic Ductal" 17237814 The expression of miR-216 and -217 and lack of expression of miR-133a were identified as characteristic of pancreas tissue. tissue_expression_ns hsa-mir-182 Preeclampsia 17346547 "Differential expression between preeclampsia and the control group (miR-210, miR-182) and between preeclampsia + SGA and the control group (miR-210, miR-182*, and others) was found." tissue_expression_ns hsa-mir-210 Preeclampsia 17346547 "Differential expression between preeclampsia and the control group (miR-210, miR-182) and between preeclampsia + SGA and the control group (miR-210, miR-182*, and others) was found." tissue_expression_ns hsa-let-7c Prostate Neoplasms 17891175 "We have analysed expression of 328 known and 152 novel human miRNAs in 10 benign peripheral zone tissues and 16 prostate cancer tissues using microarrays and found widespread, but not universal, downregulation of miRNAs in clinically localized prostate cancer relative to benign peripheral zone tissue.These findings have been verified by real-time RT-PCR assays on select miRNAs, including miR-125b, miR-145 and let-7c." tissue_expression_ns hsa-mir-125b Prostate Neoplasms 17891175 "We have analysed expression of 328 known and 152 novel human miRNAs in 10 benign peripheral zone tissues and 16 prostate cancer tissues using microarrays and found widespread, but not universal, downregulation of miRNAs in clinically localized prostate cancer relative to benign peripheral zone tissue.These findings have been verified by real-time RT-PCR assays on select miRNAs, including miR-125b, miR-145 and let-7c." tissue_expression_ns hsa-mir-145 Prostate Neoplasms 17891175 "We have analysed expression of 328 known and 152 novel human miRNAs in 10 benign peripheral zone tissues and 16 prostate cancer tissues using microarrays and found widespread, but not universal, downregulation of miRNAs in clinically localized prostate cancer relative to benign peripheral zone tissue.These findings have been verified by real-time RT-PCR assays on select miRNAs, including miR-125b, miR-145 and let-7c." tissue_expression_ns hsa-mir-15a "Leukemia, Lymphocytic, Chronic, B-Cell" 17941951 altered expression tissue_expression_ns hsa-mir-16-1 "Leukemia, Lymphocytic, Chronic, B-Cell" 17941951 altered expression tissue_expression_ns hsa-mir-142 Ovarian Neoplasms 18182067 "We selected and validated the expression of miR-20a, miR-21, miR-26a, miR-18a, miR-206, miR-181a and miR-142-5p and found their differential expression in tissue and cell-specific manners (P<0.05)." tissue_expression_ns hsa-mir-181a Ovarian Neoplasms 18182067 "We selected and validated the expression of miR-20a, miR-21, miR-26a, miR-18a, miR-206, miR-181a and miR-142-5p and found their differential expression in tissue and cell-specific manners (P<0.05)." tissue_expression_ns hsa-mir-18a Ovarian Neoplasms 18182067 "We selected and validated the expression of miR-20a, miR-21, miR-26a, miR-18a, miR-206, miR-181a and miR-142-5p and found their differential expression in tissue and cell-specific manners (P<0.05)." tissue_expression_ns hsa-mir-206 Ovarian Neoplasms 18182067 "We selected and validated the expression of miR-20a, miR-21, miR-26a, miR-18a, miR-206, miR-181a and miR-142-5p and found their differential expression in tissue and cell-specific manners (P<0.05)." tissue_expression_ns hsa-mir-20a Ovarian Neoplasms 18182067 "We selected and validated the expression of miR-20a, miR-21, miR-26a, miR-18a, miR-206, miR-181a and miR-142-5p and found their differential expression in tissue and cell-specific manners (P<0.05)." tissue_expression_ns hsa-mir-21 Ovarian Neoplasms 18182067 "We selected and validated the expression of miR-20a, miR-21, miR-26a, miR-18a, miR-206, miR-181a and miR-142-5p and found their differential expression in tissue and cell-specific manners (P<0.05)." tissue_expression_ns hsa-mir-26a Ovarian Neoplasms 18182067 "We selected and validated the expression of miR-20a, miR-21, miR-26a, miR-18a, miR-206, miR-181a and miR-142-5p and found their differential expression in tissue and cell-specific manners (P<0.05)." tissue_expression_ns hsa-let-7 Ovarian Neoplasms 18199536 "Here, we show that several miRNAs are altered in human ovarian cancer, with the most significantly deregulated miRNAs being miR-214, miR-199a*, miR-200a, miR-100, miR-125b, and let-7 cluster." tissue_expression_ns hsa-mir-100 Ovarian Neoplasms 18199536 "Here, we show that several miRNAs are altered in human ovarian cancer, with the most significantly deregulated miRNAs being miR-214, miR-199a*, miR-200a, miR-100, miR-125b, and let-7 cluster." tissue_expression_ns hsa-mir-125b Ovarian Neoplasms 18199536 "Here, we show that several miRNAs are altered in human ovarian cancer, with the most significantly deregulated miRNAs being miR-214, miR-199a*, miR-200a, miR-100, miR-125b, and let-7 cluster." tissue_expression_ns hsa-mir-199a Ovarian Neoplasms 18199536 "Here, we show that several miRNAs are altered in human ovarian cancer, with the most significantly deregulated miRNAs being miR-214, miR-199a*, miR-200a, miR-100, miR-125b, and let-7 cluster." tissue_expression_ns hsa-mir-200a Ovarian Neoplasms 18199536 "Here, we show that several miRNAs are altered in human ovarian cancer, with the most significantly deregulated miRNAs being miR-214, miR-199a*, miR-200a, miR-100, miR-125b, and let-7 cluster." tissue_expression_ns hsa-mir-146 Inflammation 18291670 Recent evidence showing altered miRNA expression in chronic inflammatory diseases (e.g. miR-203 and miR-146) suggests their involvement in immune-mediated diseases. tissue_expression_ns hsa-let-7b Melanoma 18477892 "The most significant discriminators were let-7b and miR-199a, and the expression of these miRNAs was validated by quantitative PCR." tissue_expression_ns hsa-mir-199a Melanoma 18477892 "The most significant discriminators were let-7b and miR-199a, and the expression of these miRNAs was validated by quantitative PCR." tissue_expression_ns hsa-mir-106a Autistic Disorder 18563458 miR-106a: deregulation tissue_expression_ns hsa-mir-106b Autistic Disorder 18563458 miR-106b: deregulation tissue_expression_ns hsa-mir-129-1 Autistic Disorder 18563458 miR-129: deregulation tissue_expression_ns hsa-mir-129-2 Autistic Disorder 18563458 miR-129: deregulation tissue_expression_ns hsa-mir-132 Autistic Disorder 18563458 miR-132: deregulation tissue_expression_ns hsa-mir-140 Autistic Disorder 18563458 miR-140: deregulation tissue_expression_ns hsa-mir-146b Autistic Disorder 18563458 miR-146b: deregulation tissue_expression_ns hsa-mir-148b Autistic Disorder 18563458 miR-148b: deregulation tissue_expression_ns hsa-mir-15a Autistic Disorder 18563458 miR-15a: deregulation tissue_expression_ns hsa-mir-15b Autistic Disorder 18563458 miR-15b: deregulation tissue_expression_ns hsa-mir-181d Autistic Disorder 18563458 miR-181d: deregulation tissue_expression_ns hsa-mir-193b Autistic Disorder 18563458 miR-193b: deregulation tissue_expression_ns hsa-mir-21 Autistic Disorder 18563458 miR-21: deregulation tissue_expression_ns hsa-mir-212 Autistic Disorder 18563458 miR-212: deregulation tissue_expression_ns hsa-mir-23a Autistic Disorder 18563458 miR-23a: deregulation tissue_expression_ns hsa-mir-27a Autistic Disorder 18563458 miR-27a: deregulation tissue_expression_ns hsa-mir-381 Autistic Disorder 18563458 miR-381: deregulation tissue_expression_ns hsa-mir-431 Autistic Disorder 18563458 miR-431: deregulation tissue_expression_ns hsa-mir-432 Autistic Disorder 18563458 miR-432: deregulation tissue_expression_ns hsa-mir-484 Autistic Disorder 18563458 miR-484: deregulation tissue_expression_ns hsa-mir-539 Autistic Disorder 18563458 miR-539: deregulation tissue_expression_ns hsa-mir-550a-1 Autistic Disorder 18563458 miR-550: deregulation tissue_expression_ns hsa-mir-550a-2 Autistic Disorder 18563458 miR-550: deregulation tissue_expression_ns hsa-mir-598 Autistic Disorder 18563458 miR-598: deregulation tissue_expression_ns hsa-mir-652 Autistic Disorder 18563458 miR-652: deregulation tissue_expression_ns hsa-mir-7-1 Autistic Disorder 18563458 miR-7: deregulation tissue_expression_ns hsa-mir-7-2 Autistic Disorder 18563458 miR-7: deregulation tissue_expression_ns hsa-mir-7-3 Autistic Disorder 18563458 miR-7: deregulation tissue_expression_ns hsa-mir-93 Autistic Disorder 18563458 miR-93: deregulation tissue_expression_ns hsa-mir-95 Autistic Disorder 18563458 miR-95: deregulation tissue_expression_ns hsa-mir-9-1 Brain Neoplasms 18624795 miR-9: Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors tissue_expression_ns hsa-mir-9-2 Brain Neoplasms 18624795 miR-9: Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors tissue_expression_ns hsa-mir-92b Brain Neoplasms 18624795 miR-92b: Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors tissue_expression_ns hsa-mir-9-3 Brain Neoplasms 18624795 miR-9: Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors tissue_expression_ns hsa-mir-196a-1 Pancreatic Neoplasms 18719196 "miR-196a: biomarkers improved the ability to distinguish between healthy tissue, PDAC, and chronic pancreatitis" tissue_expression_ns hsa-mir-196a-2 Pancreatic Neoplasms 18719196 "miR-196a: biomarkers improved the ability to distinguish between healthy tissue, PDAC, and chronic pancreatitis" tissue_expression_ns hsa-mir-217 Pancreatic Neoplasms 18719196 "miR-217: biomarkers improved the ability to distinguish between healthy tissue, PDAC, and chronic pancreatitis" tissue_expression_ns hsa-mir-135a Prostate Neoplasms 18831788 "In addition, microRNA microarray data from other studies confirm that several predicted microRNAs, including miR-21, miR-135a, and miR-135b, demonstrate differential expression in prostate cancer cells, comparing with normal tissues." tissue_expression_ns hsa-mir-135b Prostate Neoplasms 18831788 "In addition, microRNA microarray data from other studies confirm that several predicted microRNAs, including miR-21, miR-135a, and miR-135b, demonstrate differential expression in prostate cancer cells, comparing with normal tissues." tissue_expression_ns hsa-mir-21 Prostate Neoplasms 18831788 "In addition, microRNA microarray data from other studies confirm that several predicted microRNAs, including miR-21, miR-135a, and miR-135b, demonstrate differential expression in prostate cancer cells, comparing with normal tissues." tissue_expression_ns hsa-let-7a-1 Pituitary Adenoma 18840638 let-7a: deregulation tissue_expression_ns hsa-let-7a-2 Pituitary Adenoma 18840638 let-7a: deregulation tissue_expression_ns hsa-let-7a-3 Pituitary Adenoma 18840638 let-7a: deregulation tissue_expression_ns hsa-mir-141 Pituitary Adenoma 18840638 miR-141: deregulation tissue_expression_ns hsa-mir-143 Pituitary Adenoma 18840638 miR-143: deregulation tissue_expression_ns hsa-mir-145 Pituitary Adenoma 18840638 miR-145: deregulation tissue_expression_ns hsa-mir-150 Pituitary Adenoma 18840638 miR-150: deregulation tissue_expression_ns hsa-mir-15a Pituitary Adenoma 18840638 miR-15a: deregulation tissue_expression_ns hsa-mir-16-1 Pituitary Adenoma 18840638 miR-16: deregulation tissue_expression_ns hsa-mir-16-2 Pituitary Adenoma 18840638 miR-16: deregulation tissue_expression_ns hsa-mir-21 Pituitary Adenoma 18840638 miR-21: deregulation tissue_expression_ns hsa-mir-10b Medulloblastoma 18973228 miR-10b: different expression in tumors overexpression or not ErbB2 tissue_expression_ns hsa-mir-125b-1 Medulloblastoma 18973228 miR-125b: different expression in tumors overexpression or not ErbB2 tissue_expression_ns hsa-mir-125b-2 Medulloblastoma 18973228 miR-125b: different expression in tumors overexpression or not ErbB2 tissue_expression_ns hsa-mir-135a-1 Medulloblastoma 18973228 miR-135a: different expression in tumors overexpression or not ErbB2 tissue_expression_ns hsa-mir-135a-2 Medulloblastoma 18973228 miR-135a: different expression in tumors overexpression or not ErbB2 tissue_expression_ns hsa-mir-135b Medulloblastoma 18973228 miR-135b: different expression in tumors overexpression or not ErbB2 tissue_expression_ns hsa-mir-153-1 Medulloblastoma 18973228 miR-153: different expression in tumors overexpression or not ErbB2 tissue_expression_ns hsa-mir-153-2 Medulloblastoma 18973228 miR-153: different expression in tumors overexpression or not ErbB2 tissue_expression_ns hsa-mir-181b-1 Medulloblastoma 18973228 miR-181b: different expression in tumors overexpression or not c-Myc tissue_expression_ns hsa-mir-181b-2 Medulloblastoma 18973228 miR-181b: different expression in tumors overexpression or not c-Myc tissue_expression_ns hsa-mir-199b Medulloblastoma 18973228 miR-199b: different expression in tumors overexpression or not ErbB2 tissue_expression_ns hsa-mir-21 "Carcinoma, Hepatocellular" 19120703 "In some cases, aberrantly expressed miRNAs could be linked to cancer-associated pathways, indicating a direct role in liver tumourigenesis. For example, up-regulation of mir-221 and mir-21 could promote cell cycle progression, reduce cell death and favour angiogenesis and invasion." tissue_expression_ns hsa-mir-221 "Carcinoma, Hepatocellular" 19120703 "In some cases, aberrantly expressed miRNAs could be linked to cancer-associated pathways, indicating a direct role in liver tumourigenesis. For example, up-regulation of mir-221 and mir-21 could promote cell cycle progression, reduce cell death and favour angiogenesis and invasion." tissue_expression_ns hsa-mir-17 Azoospermia 19210773 miR-17: deregulation tissue_expression_ns hsa-mir-18a Azoospermia 19210773 miR-18a: deregulation tissue_expression_ns hsa-mir-19a Azoospermia 19210773 miR-19a: deregulation tissue_expression_ns hsa-mir-19b-1 Azoospermia 19210773 miR-19b: deregulation tissue_expression_ns hsa-mir-19b-2 Azoospermia 19210773 miR-19b: deregulation tissue_expression_ns hsa-mir-20a Azoospermia 19210773 miR-20a: deregulation tissue_expression_ns hsa-mir-302a Azoospermia 19210773 miR-302a: deregulation tissue_expression_ns hsa-mir-371a Azoospermia 19210773 mir-371: deregulation tissue_expression_ns hsa-mir-372 Azoospermia 19210773 mir-372: deregulation tissue_expression_ns hsa-mir-373 Azoospermia 19210773 mir-373: deregulation tissue_expression_ns hsa-mir-383 Azoospermia 19210773 miR-383: deregulation tissue_expression_ns hsa-mir-491 Azoospermia 19210773 miR-491-3p: deregulation tissue_expression_ns hsa-mir-520d Azoospermia 19210773 miR-520d-3p: deregulation tissue_expression_ns hsa-mir-92a-1 Azoospermia 19210773 miR-92a: deregulation tissue_expression_ns hsa-mir-92a-2 Azoospermia 19210773 miR-92a: deregulation tissue_expression_ns hsa-mir-142 Leukemia 19246560 "Here, we report aberrant expression of hematopoietic-specific miR-223, miR-181a, miR-150, miR-142.3p, and miR-155 in HTLV-I-infected cells in vitro and uncultured ex vivo ATL cells." tissue_expression_ns hsa-mir-150 Leukemia 19246560 "Here, we report aberrant expression of hematopoietic-specific miR-223, miR-181a, miR-150, miR-142.3p, and miR-155 in HTLV-I-infected cells in vitro and uncultured ex vivo ATL cells." tissue_expression_ns hsa-mir-155 Leukemia 19246560 "Here, we report aberrant expression of hematopoietic-specific miR-223, miR-181a, miR-150, miR-142.3p, and miR-155 in HTLV-I-infected cells in vitro and uncultured ex vivo ATL cells." tissue_expression_ns hsa-mir-181a Leukemia 19246560 "Here, we report aberrant expression of hematopoietic-specific miR-223, miR-181a, miR-150, miR-142.3p, and miR-155 in HTLV-I-infected cells in vitro and uncultured ex vivo ATL cells." tissue_expression_ns hsa-mir-223 Leukemia 19246560 "Here, we report aberrant expression of hematopoietic-specific miR-223, miR-181a, miR-150, miR-142.3p, and miR-155 in HTLV-I-infected cells in vitro and uncultured ex vivo ATL cells." tissue_expression_ns hsa-mir-152 Preeclampsia 19285651 miR-152: expressed differentially in preeclamptic placentas vs normal controls tissue_expression_ns hsa-mir-210 Preeclampsia 19285651 miR-210: expressed differentially in preeclamptic placentas vs normal controls tissue_expression_ns hsa-mir-411 Preeclampsia 19285651 miR-411: expressed differentially in preeclamptic placentas vs normal controls tissue_expression_ns hsa-mir-127 "Lymphoma, Large B-Cell, Diffuse" 19287466 Specific expression of miR-17-5p and miR-127 in testicular and central nervous system diffuse large B-cell lymphoma. tissue_expression_ns hsa-mir-17 "Lymphoma, Large B-Cell, Diffuse" 19287466 Specific expression of miR-17-5p and miR-127 in testicular and central nervous system diffuse large B-cell lymphoma. tissue_expression_ns hsa-mir-196a-1 Barrett Esophagus 19342367 miR-196a: Marker of Progression tissue_expression_ns hsa-mir-196a-2 Barrett Esophagus 19342367 miR-196a: Marker of Progression tissue_expression_ns hsa-mir-106a "Carcinoma, Hepatocellular" 19360909 miR-106a: involve tissue_expression_ns hsa-mir-17 "Carcinoma, Hepatocellular" 19360909 miR-17-5p: involve tissue_expression_ns hsa-mir-20a "Carcinoma, Hepatocellular" 19360909 miR-20: involve tissue_expression_ns hsa-mir-20b "Carcinoma, Hepatocellular" 19360909 miR-20: involve tissue_expression_ns hsa-mir-92a-1 "Carcinoma, Hepatocellular" 19360909 miR-92: involve tissue_expression_ns hsa-mir-92a-2 "Carcinoma, Hepatocellular" 19360909 miR-92: involve tissue_expression_ns hsa-mir-92b "Carcinoma, Hepatocellular" 19360909 miR-92: involve tissue_expression_ns hsa-mir-24 Kaposi Sarcoma 19381257 Mir-140 and Kaposi sarcoma-associated herpesvirus viral miRNAs increased linearly with the degree of transformation. Mir-24 emerged as a biomarker specific for KS. tissue_expression_ns hsa-mir-126 Lung Neoplasms 19493678 "Comparing paired lung cancer tissue with adjacent normal lung parenchyma, hsa-miR-126*, hsa-miR-145, hsa-miR-21, hsa-miR-182, hsa-miR-183 and hsa-miR-210 were found to be the most differentially expressed miRNAs." tissue_expression_ns hsa-mir-145 Lung Neoplasms 19493678 "Comparing paired lung cancer tissue with adjacent normal lung parenchyma, hsa-miR-126*, hsa-miR-145, hsa-miR-21, hsa-miR-182, hsa-miR-183 and hsa-miR-210 were found to be the most differentially expressed miRNAs." tissue_expression_ns hsa-mir-182 Lung Neoplasms 19493678 "Comparing paired lung cancer tissue with adjacent normal lung parenchyma, hsa-miR-126*, hsa-miR-145, hsa-miR-21, hsa-miR-182, hsa-miR-183 and hsa-miR-210 were found to be the most differentially expressed miRNAs." tissue_expression_ns hsa-mir-183 Lung Neoplasms 19493678 "Comparing paired lung cancer tissue with adjacent normal lung parenchyma, hsa-miR-126*, hsa-miR-145, hsa-miR-21, hsa-miR-182, hsa-miR-183 and hsa-miR-210 were found to be the most differentially expressed miRNAs." tissue_expression_ns hsa-mir-21 Lung Neoplasms 19493678 "Comparing paired lung cancer tissue with adjacent normal lung parenchyma, hsa-miR-126*, hsa-miR-145, hsa-miR-21, hsa-miR-182, hsa-miR-183 and hsa-miR-210 were found to be the most differentially expressed miRNAs." tissue_expression_ns hsa-mir-210 Lung Neoplasms 19493678 "Comparing paired lung cancer tissue with adjacent normal lung parenchyma, hsa-miR-126*, hsa-miR-145, hsa-miR-21, hsa-miR-182, hsa-miR-183 and hsa-miR-210 were found to be the most differentially expressed miRNAs." tissue_expression_ns hsa-mir-21 "Adenocarcinoma, Colon" 19547998 "differential expression, with highest expression levels in SSAs; Levels of miR-181b but not miR-21 differed in HPs and normal mucosa; SSAs exhibited both significantly higher miR-181b levels and miR-21 levels; discriminating potential diagnostic value HP from SSA" tissue_expression_ns hsa-mir-21 Myocardial Infarction 19706597 "hsa-mir-21:a remarkable example of MicroRNA expression signature; downregulated in infarcted areas, upregulated in border areas" tissue_expression_ns hsa-mir-17 Glioblastoma 19775293 "Taken together, our results support an important role of altered miRNA expression in gliomas, and suggest miR-17 and miR-184 as interesting candidates contributing to glioma progression." tissue_expression_ns hsa-mir-184 Glioblastoma 19775293 "Taken together, our results support an important role of altered miRNA expression in gliomas, and suggest miR-17 and miR-184 as interesting candidates contributing to glioma progression." tissue_expression_ns hsa-mir-34c Ovarian Neoplasms 19798417 High grade serous carcinomas as a group exhibit significant miRNA dysregulation in comparison to tubal epithelium and the levels of miR-34c and miR-422b appear to be prognostically important. tissue_expression_ns hsa-mir-422b Ovarian Neoplasms 19798417 High grade serous carcinomas as a group exhibit significant miRNA dysregulation in comparison to tubal epithelium and the levels of miR-34c and miR-422b appear to be prognostically important. tissue_expression_ns hsa-mir-141 Bladder Neoplasms 19945312 "The diagnostic test, based on the three most discriminatory miRNAs in our panel (miR-200c, miR-141, and miR-30b), showed a sensitivity of 100% and a specificity of 96.2%. Such a panel of miRNAs has the potential to identify invasive bladder tumors misclassified in pathologic assessment of bladder biopsy specimens." tissue_expression_ns hsa-mir-200c Bladder Neoplasms 19945312 "The diagnostic test, based on the three most discriminatory miRNAs in our panel (miR-200c, miR-141, and miR-30b), showed a sensitivity of 100% and a specificity of 96.2%. Such a panel of miRNAs has the potential to identify invasive bladder tumors misclassified in pathologic assessment of bladder biopsy specimens." tissue_expression_ns hsa-mir-30b Bladder Neoplasms 19945312 "The diagnostic test, based on the three most discriminatory miRNAs in our panel (miR-200c, miR-141, and miR-30b), showed a sensitivity of 100% and a specificity of 96.2%. Such a panel of miRNAs has the potential to identify invasive bladder tumors misclassified in pathologic assessment of bladder biopsy specimens." tissue_expression_ns hsa-mir-141 Prostate Neoplasms 20014922 "Promising molecular markers identified from gene expression profiling studies include AMACR, EZH2, TMPRSS2-ERG, miR-221 and miR-141, which are described in more detail." tissue_expression_ns hsa-mir-221 Prostate Neoplasms 20014922 "Promising molecular markers identified from gene expression profiling studies include AMACR, EZH2, TMPRSS2-ERG, miR-221 and miR-141, which are described in more detail." tissue_expression_ns hsa-mir-1 Cardiomegaly 20015039 "Lately, some highlight articles revealed that the altered expression of miRNAs such as miR-1, miR-133, miR-21, miR-208 etc in hearts also contributed to cardiovascular diseases, such as heart ischemia, cardiac hypertrophy, and arrhythmias." tissue_expression_ns hsa-mir-133 Vascular Hypertrophy 20015039 "Lately, some highlight articles revealed that the altered expression of miRNAs such as miR-1, miR-133, miR-21, miR-208 etc in hearts also contributed to cardiovascular diseases, such as heart ischemia, cardiac hypertrophy, and arrhythmias." tissue_expression_ns hsa-mir-208 Vascular Hypertrophy 20015039 "Lately, some highlight articles revealed that the altered expression of miRNAs such as miR-1, miR-133, miR-21, miR-208 etc in hearts also contributed to cardiovascular diseases, such as heart ischemia, cardiac hypertrophy, and arrhythmias." tissue_expression_ns hsa-mir-21 Cardiomegaly 20015039 "Lately, some highlight articles revealed that the altered expression of miRNAs such as miR-1, miR-133, miR-21, miR-208 etc in hearts also contributed to cardiovascular diseases, such as heart ischemia, cardiac hypertrophy, and arrhythmias." tissue_expression_ns hsa-mir-143 Neoplasms [unspecific] 20064147 "Overall, the current study suggests that miR-143 is ubiquitously expressed among tissues and is likely to be involved in the regulation of cell proliferation and apoptosis." tissue_expression_ns hsa-mir-133b Myocardial Infarction 20075508 dysregulation tissue_expression_ns hsa-mir-150 Myocardial Infarction 20075508 dysregulation tissue_expression_ns hsa-mir-186 Myocardial Infarction 20075508 dysregulation tissue_expression_ns hsa-mir-210 Myocardial Infarction 20075508 dysregulation tissue_expression_ns hsa-mir-451a Myocardial Infarction 20075508 dysregulation tissue_expression_ns hsa-mir-10a Breast Neoplasms 20099276 "miR-10a:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c" tissue_expression_ns hsa-mir-146a Breast Neoplasms 20099276 "miR-146a:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c" tissue_expression_ns hsa-mir-200b Breast Neoplasms 20099276 "miR-200b:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c" tissue_expression_ns hsa-mir-200c Breast Neoplasms 20099276 "miR-200c:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c" tissue_expression_ns hsa-mir-221 Breast Neoplasms 20099276 "miR-221:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c" tissue_expression_ns hsa-mir-222 Breast Neoplasms 20099276 "miR-222:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c" tissue_expression_ns hsa-mir-345 Breast Neoplasms 20099276 "miR-345:dysregulated miRNAs were miR-146a, miR-10a, miR-221/222, miR-345, miR-200b and miR-200c" tissue_expression_ns hsa-mir-221 "Leukemia, Myelogenous, Chronic, BCR-ABL Positive" 20299489 "Among them, the expression of miR-34a, miR-221, and miR-222 was induced in the early stages and maintained throughout the late stages of differentiation." tissue_expression_ns hsa-mir-222 "Leukemia, Myelogenous, Chronic, BCR-ABL Positive" 20299489 "Among them, the expression of miR-34a, miR-221, and miR-222 was induced in the early stages and maintained throughout the late stages of differentiation." tissue_expression_ns hsa-mir-34a "Leukemia, Myelogenous, Chronic, BCR-ABL Positive" 20299489 "Among them, the expression of miR-34a, miR-221, and miR-222 was induced in the early stages and maintained throughout the late stages of differentiation." tissue_expression_ns hsa-mir-204 Melanoma 20302635 "Although the number of cases is small, positive lymph node status in the two age groups was characterized by the statistically significant expression of hsa-miR-30a* and hsa-miR-204 (F-test, p-value < 0.001)." tissue_expression_ns hsa-mir-30a Melanoma 20302635 "Although the number of cases is small, positive lymph node status in the two age groups was characterized by the statistically significant expression of hsa-miR-30a* and hsa-miR-204 (F-test, p-value < 0.001)." tissue_expression_ns hsa-mir-16 Breast Adenocarcinoma 20433153 "Using isolated total RNA from human breast adenocarcinoma MCF-7 cells, the assay detected specifically miR-21 and miR-16 in parallel, and higher expression of oncogene miR-21 compared to miR-16 was demonstrated." tissue_expression_ns hsa-mir-21 Breast Adenocarcinoma 20433153 "Using isolated total RNA from human breast adenocarcinoma MCF-7 cells, the assay detected specifically miR-21 and miR-16 in parallel, and higher expression of oncogene miR-21 compared to miR-16 was demonstrated." tissue_expression_ns hsa-mir-146b "Carcinoma, Thyroid, Papillary" 20459574 Hyalinizing trabecular tumour of the thyroid-differential expression of distinct miRNAs compared with papillary thyroid carcinoma. tissue_expression_ns hsa-mir-182 Glioma 20472885 miR-182 as a prognostic marker for glioma progression and patient survival. tissue_expression_ns hsa-mir-200a Neoplasms [unspecific] 20498632 miR-200a:altered microRNA signatures as potent markers for ATCs tissue_expression_ns hsa-mir-200b Neoplasms [unspecific] 20498632 miR-200b:altered microRNA signatures as potent markers for ATCs tissue_expression_ns hsa-mir-200c Neoplasms [unspecific] 20498632 miR-200c:altered microRNA signatures as potent markers for ATCs tissue_expression_ns hsa-mir-21 Neoplasms [unspecific] 20498632 miR-21:altered microRNA signatures as potent markers for ATCs tissue_expression_ns hsa-mir-30a Neoplasms [unspecific] 20498632 miR-30:altered microRNA signatures as potent markers for ATCs tissue_expression_ns hsa-mir-92a-1 "Carcinoma, Hepatocellular" 20518884 miR-92a:Deregulation of miR-92a expression is implicated in hepatocellular carcinoma development tissue_expression_ns hsa-mir-92a-2 "Carcinoma, Hepatocellular" 20518884 miR-92a:Deregulation of miR-92a expression is implicated in hepatocellular carcinoma development tissue_expression_ns hsa-mir-101 Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-125b Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-126 Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-141 Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-146a Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-200a Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-200b Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-200c Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-21 Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-221 Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-222 Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-330 Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-34 Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-429 Prostate Neoplasms 20539944 "The aim of this review is to describe the mechanisms of several known miRNAs, summarize recent studies on the relevance of altered expression of oncogenic miRNAs (e.g. miR-221/-222, miR-21, and miR-125b) and tumor suppressor miRNAs (e.g. miR-101, miR-126*, miR-146a, miR-330, miR-34 cluster, and miR-200 family) for PCa." tissue_expression_ns hsa-mir-15b Inflammation 20564181 "Of note, differentially expressed miRNAs (hsa-miR-15b and 181b) may have a potential role in regulating these processes." tissue_expression_ns hsa-mir-181b Inflammation 20564181 "Of note, differentially expressed miRNAs (hsa-miR-15b and 181b) may have a potential role in regulating these processes." tissue_expression_ns hsa-mir-10a "Squamous Cell Carcinoma, Esophageal" 20588024 "We found that miR-205 and miR-10a were significantly altered in cellular expression, and might be specific for ESCC with potential roles in the pathogenesis. " tissue_expression_ns hsa-mir-205 "Squamous Cell Carcinoma, Esophageal" 20588024 "We found that miR-205 and miR-10a were significantly altered in cellular expression, and might be specific for ESCC with potential roles in the pathogenesis. " tissue_expression_ns hsa-mir-130a "Carcinoma, Lung, Non-Small-Cell" 20625274 Multivariate Cox regression analysis showed that miRNA-130a was an independent prognostic factor for patients with NSCLC. tissue_expression_ns hsa-mir-106a "Carcinoma, Esophageal" 20628822 "Furthermore, miR-106a and miR-148a expression correlates with disease recurrence and tumor-related mortality." tissue_expression_ns hsa-mir-148a "Carcinoma, Esophageal" 20628822 "Furthermore, miR-106a and miR-148a expression correlates with disease recurrence and tumor-related mortality." tissue_expression_ns hsa-mir-205 "Carcinoma, Esophageal" 20628822 "The expression of miR-21, miR-106a, miR-148a, miR-205 in formalin-fixed paraffin-embedded specimens was evaluated by TaqMan qPCR assays. Expression was compared with clinicopathological features of the cancers and outcome." tissue_expression_ns hsa-mir-21 "Carcinoma, Esophageal" 20628822 "The expression of miR-21, miR-106a, miR-148a, miR-205 in formalin-fixed paraffin-embedded specimens was evaluated by TaqMan qPCR assays. Expression was compared with clinicopathological features of the cancers and outcome." tissue_expression_ns hsa-mir-146a Ischemia-Reperfusion Injury 20651252 "miR-146a:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI" tissue_expression_ns hsa-mir-187 Ischemia-Reperfusion Injury 20651252 "miR-187:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI" tissue_expression_ns hsa-mir-192 Ischemia-Reperfusion Injury 20651252 "miR-192:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI" tissue_expression_ns hsa-mir-194-1 Ischemia-Reperfusion Injury 20651252 "miR-194:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI" tissue_expression_ns hsa-mir-194-2 Ischemia-Reperfusion Injury 20651252 "miR-194:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI" tissue_expression_ns hsa-mir-199a-1 Ischemia-Reperfusion Injury 20651252 "miR-199a-3p:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI" tissue_expression_ns hsa-mir-199a-2 Ischemia-Reperfusion Injury 20651252 "miR-199a-3p:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI" tissue_expression_ns hsa-mir-20a Ischemia-Reperfusion Injury 20651252 "miR-20a:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI" tissue_expression_ns hsa-mir-21 Ischemia-Reperfusion Injury 20651252 "miR-21:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI" tissue_expression_ns hsa-mir-214 Ischemia-Reperfusion Injury 20651252 "miR-214:nine miRNAs (miR-21, miR-20a,miR-146a, miR-199a-3p, miR-214, miR-192, miR-187, miR-805, and miR-194) that are differentially expressed following IRI" tissue_expression_ns hsa-mir-203 Choriocarcinoma 20652642 miR-203 expression is a new prognostic marker in pancreatic adenocarcinoma patients. tissue_expression_ns hsa-mir-125b Ovarian Neoplasms 20658525 Our results suggest that aberrantly expressed miR-125b may contribute to OC development. tissue_expression_ns hsa-mir-155 Breast Neoplasms 20664596 "miR-155:miR-155, is differentially expressed in ER- versus ER+ tumors" tissue_expression_ns hsa-mir-29a Breast Neoplasms 20664596 "miR-29a:We identified a set of 13 miRNAs of which expression differed between IBC and non-IBC, making these miRNAs candidate markers for the IBC subtype" tissue_expression_ns hsa-mir-30b Breast Neoplasms 20664596 "miR-30b:We identified a set of 13 miRNAs of which expression differed between IBC and non-IBC, making these miRNAs candidate markers for the IBC subtype" tissue_expression_ns hsa-mir-342 Breast Neoplasms 20664596 "miR-342-3p:We identified a set of 13 miRNAs of which expression differed between IBC and non-IBC, making these miRNAs candidate markers for the IBC subtype" tissue_expression_ns hsa-mir-520a Breast Neoplasms 20664596 "miR-520a-5p:We identified a set of 13 miRNAs of which expression differed between IBC and non-IBC, making these miRNAs candidate markers for the IBC subtype" tissue_expression_ns hsa-mir-126 Immune System Disease [unspecific] 20682703 "Although altered expressions of miR-21 and miR-34a were manifested within cancer cells, those of miR-126 and miR-155 were predominantly confined to endothelial cells and immune cells, respectively." tissue_expression_ns hsa-mir-155 Immune System Disease [unspecific] 20682703 "Although altered expressions of miR-21 and miR-34a were manifested within cancer cells, those of miR-126 and miR-155 were predominantly confined to endothelial cells and immune cells, respectively." tissue_expression_ns hsa-mir-21 "Carcinoma, Rectal" 20682703 "Although altered expressions of miR-21 and miR-34a were manifested within cancer cells, those of miR-126 and miR-155 were predominantly confined to endothelial cells and immune cells, respectively." tissue_expression_ns hsa-mir-34a "Carcinoma, Rectal" 20682703 "Although altered expressions of miR-21 and miR-34a were manifested within cancer cells, those of miR-126 and miR-155 were predominantly confined to endothelial cells and immune cells, respectively." tissue_expression_ns hsa-mir-103a-1 Gastric Neoplasms 20726036 "miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers" tissue_expression_ns hsa-mir-103a-2 Gastric Neoplasms 20726036 "miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers" tissue_expression_ns hsa-mir-106b Gastric Neoplasms 20726036 "miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers" tissue_expression_ns hsa-mir-145 Gastric Neoplasms 20726036 "miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers" tissue_expression_ns hsa-mir-146a Gastric Neoplasms 20726036 "miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers" tissue_expression_ns hsa-mir-148a Gastric Neoplasms 20726036 "miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers" tissue_expression_ns hsa-mir-21 Gastric Neoplasms 20726036 "miR-103, miR-21, miR-145, miR-106b, miR-146a, and miR-148a separated node-positive from node-negative gastric cancers" tissue_expression_ns hsa-let-7g Lung Neoplasms 20818338 "Four miRNAs (miR-155, miR-25, miR-495 and miR-7g) were expressed differently among these tumors. miR-155 was upregulated only in EGFR/KRAS-negative group, miR-25 was upregulated only in EGFR-positive group and miR-495 was upregulated only in KRAS-positive adenocarcinomas. " tissue_expression_ns hsa-mir-155 Lung Neoplasms 20818338 "Four miRNAs (miR-155, miR-25, miR-495 and miR-7g) were expressed differently among these tumors. miR-155 was upregulated only in EGFR/KRAS-negative group, miR-25 was upregulated only in EGFR-positive group and miR-495 was upregulated only in KRAS-positive adenocarcinomas. " tissue_expression_ns hsa-mir-25 Lung Neoplasms 20818338 "Four miRNAs (miR-155, miR-25, miR-495 and miR-7g) were expressed differently among these tumors. miR-155 was upregulated only in EGFR/KRAS-negative group, miR-25 was upregulated only in EGFR-positive group and miR-495 was upregulated only in KRAS-positive adenocarcinomas. " tissue_expression_ns hsa-mir-495 Lung Neoplasms 20818338 "Four miRNAs (miR-155, miR-25, miR-495 and miR-7g) were expressed differently among these tumors. miR-155 was upregulated only in EGFR/KRAS-negative group, miR-25 was upregulated only in EGFR-positive group and miR-495 was upregulated only in KRAS-positive adenocarcinomas. " tissue_expression_ns hsa-mir-31 Inflammatory Bowel Diseases 20848542 Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel disease-associated neoplastic transformation. tissue_expression_ns hsa-let-7d Prostate Neoplasms 20873592 "The expression profiles of the microRNAs let-7d, let-7g, miR-98, miR-96, miR-182 and miR-183 reflect the biological behavior of PCa to some extent, and might be important biomarkers for the early detection and prognostic assessment of prostate cancer." tissue_expression_ns hsa-let-7g Prostate Neoplasms 20873592 "The expression profiles of the microRNAs let-7d, let-7g, miR-98, miR-96, miR-182 and miR-183 reflect the biological behavior of PCa to some extent, and might be important biomarkers for the early detection and prognostic assessment of prostate cancer." tissue_expression_ns hsa-mir-182 Prostate Neoplasms 20873592 "The expression profiles of the microRNAs let-7d, let-7g, miR-98, miR-96, miR-182 and miR-183 reflect the biological behavior of PCa to some extent, and might be important biomarkers for the early detection and prognostic assessment of prostate cancer." tissue_expression_ns hsa-mir-183 Prostate Neoplasms 20873592 "The expression profiles of the microRNAs let-7d, let-7g, miR-98, miR-96, miR-182 and miR-183 reflect the biological behavior of PCa to some extent, and might be important biomarkers for the early detection and prognostic assessment of prostate cancer." tissue_expression_ns hsa-mir-96 Prostate Neoplasms 20873592 "The expression profiles of the microRNAs let-7d, let-7g, miR-98, miR-96, miR-182 and miR-183 reflect the biological behavior of PCa to some extent, and might be important biomarkers for the early detection and prognostic assessment of prostate cancer." tissue_expression_ns hsa-mir-98 Prostate Neoplasms 20873592 "The expression profiles of the microRNAs let-7d, let-7g, miR-98, miR-96, miR-182 and miR-183 reflect the biological behavior of PCa to some extent, and might be important biomarkers for the early detection and prognostic assessment of prostate cancer." tissue_expression_ns hsa-mir-210 Lung Neoplasms 20885442 These observations help explain contradictory data regarding miR-210 expression and its putative function in solid tumors. tissue_expression_ns hsa-mir-125b Prostate Neoplasms 20890088 "Normalization of the four miRNAs hsa-miR-96, hsa- miR-125b, hsa-miR-205, and hsa-miR-375, which were previously shown to be regulated, shows that normalization to hsa-mir-16 can lead to biased results." tissue_expression_ns hsa-mir-16 Prostate Neoplasms 20890088 "Normalization of the four miRNAs hsa-miR-96, hsa- miR-125b, hsa-miR-205, and hsa-miR-375, which were previously shown to be regulated, shows that normalization to hsa-mir-16 can lead to biased results." tissue_expression_ns hsa-mir-205 Prostate Neoplasms 20890088 "Normalization of the four miRNAs hsa-miR-96, hsa- miR-125b, hsa-miR-205, and hsa-miR-375, which were previously shown to be regulated, shows that normalization to hsa-mir-16 can lead to biased results." tissue_expression_ns hsa-mir-375 Prostate Neoplasms 20890088 "Normalization of the four miRNAs hsa-miR-96, hsa- miR-125b, hsa-miR-205, and hsa-miR-375, which were previously shown to be regulated, shows that normalization to hsa-mir-16 can lead to biased results." tissue_expression_ns hsa-mir-96 Prostate Neoplasms 20890088 "Normalization of the four miRNAs hsa-miR-96, hsa- miR-125b, hsa-miR-205, and hsa-miR-375, which were previously shown to be regulated, shows that normalization to hsa-mir-16 can lead to biased results." tissue_expression_ns hsa-let-7a Prostate Neoplasms 20944140 "The aim of our study was to assess the expression of mir-20a, let-7a, miR-15a and miR-16 in prostate cancer (PCa) and benign prostatic hyperplasia (BPH) tissue and to investigate the relation between the expression of miRNAs and the clinicopathological features of PCa." tissue_expression_ns hsa-mir-15a Prostate Neoplasms 20944140 "The aim of our study was to assess the expression of mir-20a, let-7a, miR-15a and miR-16 in prostate cancer (PCa) and benign prostatic hyperplasia (BPH) tissue and to investigate the relation between the expression of miRNAs and the clinicopathological features of PCa." tissue_expression_ns hsa-mir-16 Prostate Neoplasms 20944140 "The aim of our study was to assess the expression of mir-20a, let-7a, miR-15a and miR-16 in prostate cancer (PCa) and benign prostatic hyperplasia (BPH) tissue and to investigate the relation between the expression of miRNAs and the clinicopathological features of PCa." tissue_expression_ns hsa-mir-20a Prostate Neoplasms 20944140 "The aim of our study was to assess the expression of mir-20a, let-7a, miR-15a and miR-16 in prostate cancer (PCa) and benign prostatic hyperplasia (BPH) tissue and to investigate the relation between the expression of miRNAs and the clinicopathological features of PCa." tissue_expression_ns hsa-let-7a "Carcinoma, Lung, Non-Small-Cell" 20975375 "In an exploratory study, we determined whether expression of six miRNAs (let-7a, miR-7, miR-21, miR-155, miR-210, and miR-221) previously reported to correlate with invasiveness or outcome in various human malignancies were associated with tumor recurrence in patients with resected stage I NSCLC." tissue_expression_ns hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 20975375 "In an exploratory study, we determined whether expression of six miRNAs (let-7a, miR-7, miR-21, miR-155, miR-210, and miR-221) previously reported to correlate with invasiveness or outcome in various human malignancies were associated with tumor recurrence in patients with resected stage I NSCLC." tissue_expression_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 20975375 "In an exploratory study, we determined whether expression of six miRNAs (let-7a, miR-7, miR-21, miR-155, miR-210, and miR-221) previously reported to correlate with invasiveness or outcome in various human malignancies were associated with tumor recurrence in patients with resected stage I NSCLC." tissue_expression_ns hsa-mir-210 "Carcinoma, Lung, Non-Small-Cell" 20975375 "In an exploratory study, we determined whether expression of six miRNAs (let-7a, miR-7, miR-21, miR-155, miR-210, and miR-221) previously reported to correlate with invasiveness or outcome in various human malignancies were associated with tumor recurrence in patients with resected stage I NSCLC." tissue_expression_ns hsa-mir-221 "Carcinoma, Lung, Non-Small-Cell" 20975375 "In an exploratory study, we determined whether expression of six miRNAs (let-7a, miR-7, miR-21, miR-155, miR-210, and miR-221) previously reported to correlate with invasiveness or outcome in various human malignancies were associated with tumor recurrence in patients with resected stage I NSCLC." tissue_expression_ns hsa-mir-7 "Carcinoma, Lung, Non-Small-Cell" 20975375 "In an exploratory study, we determined whether expression of six miRNAs (let-7a, miR-7, miR-21, miR-155, miR-210, and miR-221) previously reported to correlate with invasiveness or outcome in various human malignancies were associated with tumor recurrence in patients with resected stage I NSCLC." tissue_expression_ns hsa-let-7a "Carcinoma, Lung, Non-Small-Cell" 20978195 "We also analyzed the association of TP53 mutation status and miR-34a/b/c expression, epidermal growth factor receptor and KRAS mutation status, and miR-21 and Let-7a expression." tissue_expression_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 20978195 "We also analyzed the association of TP53 mutation status and miR-34a/b/c expression, epidermal growth factor receptor and KRAS mutation status, and miR-21 and Let-7a expression." tissue_expression_ns hsa-mir-34a "Carcinoma, Lung, Non-Small-Cell" 20978195 "We also analyzed the association of TP53 mutation status and miR-34a/b/c expression, epidermal growth factor receptor and KRAS mutation status, and miR-21 and Let-7a expression." tissue_expression_ns hsa-mir-34b "Carcinoma, Lung, Non-Small-Cell" 20978195 "We also analyzed the association of TP53 mutation status and miR-34a/b/c expression, epidermal growth factor receptor and KRAS mutation status, and miR-21 and Let-7a expression." tissue_expression_ns hsa-mir-34c "Carcinoma, Lung, Non-Small-Cell" 20978195 "We also analyzed the association of TP53 mutation status and miR-34a/b/c expression, epidermal growth factor receptor and KRAS mutation status, and miR-21 and Let-7a expression." tissue_expression_ns hsa-mir-155 "Adenocarcinoma, Pancreatic Ductal" 21068491 MicroRNA-21 and microRNA-155 in pancreatic juice have the potential of becoming biomarkers for diagnosing pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 21068491 MicroRNA-21 and microRNA-155 in pancreatic juice have the potential of becoming biomarkers for diagnosing pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-153 Ovarian Neoplasms 21083603 "Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours." tissue_expression_ns hsa-mir-485 Ovarian Neoplasms 21083603 "Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours." tissue_expression_ns hsa-mir-519a Ovarian Neoplasms 21083603 "Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumours." tissue_expression_ns hsa-let-7a Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-let-7b Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-let-7c Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-let-7d Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-let-7e Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-let-7f Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-let-7g Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-let-7i Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-mir-126 Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-mir-15a Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-mir-202 Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-mir-21 Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-mir-25 Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-mir-98 Lung Neoplasms 21102586 "In AD cases,a SNP within the same haplotype was associated with reduced RNASEN mRNA expression (P=0.013) and with miR expression changes (global P=0.007) of miRs known to be associated with cancer(e.g.,let-7 family, miR-21, miR-25, miR-126 and miR15a)." tissue_expression_ns hsa-mir-15a Pancreatic Neoplasms 21106054 Dysregulation of miR-15a and miR-214 in human pancreatic cancer. tissue_expression_ns hsa-mir-214 Pancreatic Neoplasms 21106054 Dysregulation of miR-15a and miR-214 in human pancreatic cancer. tissue_expression_ns hsa-mir-133a Bone Disease [unspecific] 21108928 "The expression of miRNAs, including miR-18a, miR-133a, miR-141 and miR-19a, was significantly altered in the PDLSCs cultured with ibandronate." tissue_expression_ns hsa-mir-141 Bone Disease [unspecific] 21108928 "The expression of miRNAs, including miR-18a, miR-133a, miR-141 and miR-19a, was significantly altered in the PDLSCs cultured with ibandronate." tissue_expression_ns hsa-mir-18a Bone Disease [unspecific] 21108928 "The expression of miRNAs, including miR-18a, miR-133a, miR-141 and miR-19a, was significantly altered in the PDLSCs cultured with ibandronate." tissue_expression_ns hsa-mir-19a Bone Disease [unspecific] 21108928 "The expression of miRNAs, including miR-18a, miR-133a, miR-141 and miR-19a, was significantly altered in the PDLSCs cultured with ibandronate." tissue_expression_ns hsa-mir-1-1 Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-1-2 Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-125b-1 Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-125b-2 Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-133a-1 Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-133a-2 Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-133b Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-143 Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-145 Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-200b Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-708 Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-99a Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-99b Urinary Bladder Cancer 21133599 dysregulated tissue_expression_ns hsa-mir-129-1 Brain Neoplasms 21157891 "MicroRNA-129, miR-142-5p, and miR-25 were differ entially expressed in every pediatric brain tumor type compared to normal tissue controls as measured by microarray." tissue_expression_ns hsa-mir-129-2 Brain Neoplasms 21157891 "MicroRNA-129, miR-142-5p, and miR-25 were differ entially expressed in every pediatric brain tumor type compared to normal tissue controls as measured by microarray." tissue_expression_ns hsa-let-7c Nevus 21166724 The microRNA molecular signature of atypic and common acquired melanocytic nevi: differential expression of miR-125b and let-7c. tissue_expression_ns hsa-mir-125b-1 Nevus 21166724 The microRNA molecular signature of atypic and common acquired melanocytic nevi: differential expression of miR-125b and let-7c. tissue_expression_ns hsa-mir-125b-2 Nevus 21166724 The microRNA molecular signature of atypic and common acquired melanocytic nevi: differential expression of miR-125b and let-7c. tissue_expression_ns hsa-mir-29a "Aortic Aneurysm, Thoracic" 21334170 dysregulated tissue_expression_ns hsa-mir-29b-1 "Aortic Aneurysm, Thoracic" 21334170 dysregulated tissue_expression_ns hsa-mir-29b-2 "Aortic Aneurysm, Thoracic" 21334170 dysregulated tissue_expression_ns hsa-mir-29c "Aortic Aneurysm, Thoracic" 21334170 dysregulated tissue_expression_ns hsa-mir-30a "Aortic Aneurysm, Thoracic" 21334170 dysregulated tissue_expression_ns hsa-mir-30b "Aortic Aneurysm, Thoracic" 21334170 dysregulated tissue_expression_ns hsa-mir-30c-1 "Aortic Aneurysm, Thoracic" 21334170 dysregulated tissue_expression_ns hsa-mir-30c-2 "Aortic Aneurysm, Thoracic" 21334170 dysregulated tissue_expression_ns hsa-mir-30d "Aortic Aneurysm, Thoracic" 21334170 dysregulated tissue_expression_ns hsa-mir-30e "Aortic Aneurysm, Thoracic" 21334170 dysregulated tissue_expression_ns hsa-mir-125a Endometriosis 21335415 "TaqMan real-time PCR was used to assess the expression of the miRNAs (miR-15b, -16, -17-5p, -20a, -21, -125a, -221 and -222), while VEGF-A and TSP-1 mRNA were assessed by real-time PCR, with SYBR Green I and VEGF-A and TSP-1 protein levels were quantified by ELISA." tissue_expression_ns hsa-mir-15b Endometriosis 21335415 "TaqMan real-time PCR was used to assess the expression of the miRNAs (miR-15b, -16, -17-5p, -20a, -21, -125a, -221 and -222), while VEGF-A and TSP-1 mRNA were assessed by real-time PCR, with SYBR Green I and VEGF-A and TSP-1 protein levels were quantified by ELISA." tissue_expression_ns hsa-mir-16 Endometriosis 21335415 "TaqMan real-time PCR was used to assess the expression of the miRNAs (miR-15b, -16, -17-5p, -20a, -21, -125a, -221 and -222), while VEGF-A and TSP-1 mRNA were assessed by real-time PCR, with SYBR Green I and VEGF-A and TSP-1 protein levels were quantified by ELISA." tissue_expression_ns hsa-mir-17 Endometriosis 21335415 "TaqMan real-time PCR was used to assess the expression of the miRNAs (miR-15b, -16, -17-5p, -20a, -21, -125a, -221 and -222), while VEGF-A and TSP-1 mRNA were assessed by real-time PCR, with SYBR Green I and VEGF-A and TSP-1 protein levels were quantified by ELISA." tissue_expression_ns hsa-mir-20a Endometriosis 21335415 "TaqMan real-time PCR was used to assess the expression of the miRNAs (miR-15b, -16, -17-5p, -20a, -21, -125a, -221 and -222), while VEGF-A and TSP-1 mRNA were assessed by real-time PCR, with SYBR Green I and VEGF-A and TSP-1 protein levels were quantified by ELISA." tissue_expression_ns hsa-mir-21 Endometriosis 21335415 "TaqMan real-time PCR was used to assess the expression of the miRNAs (miR-15b, -16, -17-5p, -20a, -21, -125a, -221 and -222), while VEGF-A and TSP-1 mRNA were assessed by real-time PCR, with SYBR Green I and VEGF-A and TSP-1 protein levels were quantified by ELISA." tissue_expression_ns hsa-mir-221 Endometriosis 21335415 "TaqMan real-time PCR was used to assess the expression of the miRNAs (miR-15b, -16, -17-5p, -20a, -21, -125a, -221 and -222), while VEGF-A and TSP-1 mRNA were assessed by real-time PCR, with SYBR Green I and VEGF-A and TSP-1 protein levels were quantified by ELISA." tissue_expression_ns hsa-mir-222 Endometriosis 21335415 "TaqMan real-time PCR was used to assess the expression of the miRNAs (miR-15b, -16, -17-5p, -20a, -21, -125a, -221 and -222), while VEGF-A and TSP-1 mRNA were assessed by real-time PCR, with SYBR Green I and VEGF-A and TSP-1 protein levels were quantified by ELISA." tissue_expression_ns hsa-mir-182 Mesothelioma 21358347 dysregulated tissue_expression_ns hsa-mir-214 Mesothelioma 21358347 dysregulated tissue_expression_ns hsa-mir-497 Mesothelioma 21358347 dysregulated tissue_expression_ns hsa-mir-7-1 Mesothelioma 21358347 dysregulated tissue_expression_ns hsa-mir-7-2 Mesothelioma 21358347 dysregulated tissue_expression_ns hsa-mir-7-3 Mesothelioma 21358347 dysregulated tissue_expression_ns hsa-mir-21 Ischemia 21373187 deregulated tissue_expression_ns hsa-mir-29b-1 Ischemia 21373187 deregulated tissue_expression_ns hsa-mir-29b-2 Ischemia 21373187 deregulated tissue_expression_ns hsa-mir-30b Ischemia 21373187 deregulated tissue_expression_ns hsa-mir-125b-1 Breast Neoplasms 21375733 dysregulated tissue_expression_ns hsa-mir-125b-2 Breast Neoplasms 21375733 dysregulated tissue_expression_ns hsa-mir-182 Breast Neoplasms 21375733 dysregulated tissue_expression_ns hsa-mir-183 Breast Neoplasms 21375733 dysregulated tissue_expression_ns hsa-mir-195 Breast Neoplasms 21375733 dysregulated tissue_expression_ns hsa-mir-1-1 Myocardial Infarction 21386882 "miR-1, miR-29b and miR-98 dysregulated." tissue_expression_ns hsa-mir-1-2 Myocardial Infarction 21386882 "miR-1, miR-29b and miR-98 dysregulated." tissue_expression_ns hsa-mir-29b-1 Myocardial Infarction 21386882 "miR-1, miR-29b and miR-98 dysregulated." tissue_expression_ns hsa-mir-29b-2 Myocardial Infarction 21386882 "miR-1, miR-29b and miR-98 dysregulated." tissue_expression_ns hsa-mir-98 Myocardial Infarction 21386882 "miR-1, miR-29b and miR-98 dysregulated." tissue_expression_ns hsa-mir-143 Prostate Neoplasms 21400514 "The differential expression of miRNAs miR-375, miR-143 and miR-145 was validated by quantitative PCR. MiRNA in situ hybridization revealed that the differential expression is cancer-cell associated." tissue_expression_ns hsa-mir-145 Prostate Neoplasms 21400514 "The differential expression of miRNAs miR-375, miR-143 and miR-145 was validated by quantitative PCR. MiRNA in situ hybridization revealed that the differential expression is cancer-cell associated." tissue_expression_ns hsa-mir-375 Prostate Neoplasms 21400514 "The differential expression of miRNAs miR-375, miR-143 and miR-145 was validated by quantitative PCR. MiRNA in situ hybridization revealed that the differential expression is cancer-cell associated." tissue_expression_ns hsa-let-7a-1 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. tissue_expression_ns hsa-let-7a-2 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. tissue_expression_ns hsa-let-7a-3 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. tissue_expression_ns hsa-mir-145 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. tissue_expression_ns hsa-mir-15b Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. tissue_expression_ns hsa-mir-203 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. tissue_expression_ns hsa-mir-21 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. tissue_expression_ns hsa-mir-486 Barrett Esophagus 21407181 differential expression between Barrett Esophagus patients with and without dysplasia. tissue_expression_ns hsa-let-7i Cerebral Malaria 21422175 "We identified three miRNAs that were differentially expressed in the brain of PbA-infected CBA mice: let7i, miR-27a, and miR-150." tissue_expression_ns hsa-mir-150 Cerebral Malaria 21422175 "We identified three miRNAs that were differentially expressed in the brain of PbA-infected CBA mice: let7i, miR-27a, and miR-150." tissue_expression_ns hsa-mir-27a Cerebral Malaria 21422175 "We identified three miRNAs that were differentially expressed in the brain of PbA-infected CBA mice: let7i, miR-27a, and miR-150." tissue_expression_ns hsa-mir-196a-1 Pancreatic Neoplasms 21463235 altered expression tissue_expression_ns hsa-mir-196a-2 Pancreatic Neoplasms 21463235 altered expression tissue_expression_ns hsa-mir-217 Pancreatic Neoplasms 21463235 altered expression tissue_expression_ns hsa-mir-133a-1 Colorectal Carcinoma 21532750 "miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors." tissue_expression_ns hsa-mir-133a-2 Colorectal Carcinoma 21532750 "miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors." tissue_expression_ns hsa-mir-135b Colorectal Carcinoma 21532750 "miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors." tissue_expression_ns hsa-mir-137 Colorectal Carcinoma 21532750 "miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors." tissue_expression_ns hsa-mir-215 Colorectal Carcinoma 21532750 "miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors." tissue_expression_ns hsa-mir-218-1 Colorectal Carcinoma 21532750 "miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors." tissue_expression_ns hsa-mir-218-2 Colorectal Carcinoma 21532750 "miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors." tissue_expression_ns hsa-mir-31 Colorectal Carcinoma 21532750 "miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors." tissue_expression_ns hsa-mir-708 Colorectal Carcinoma 21532750 "miR-215, miR-137, miR-708, miR-31,and miR-135b were differentially expressed in APC tumors and miR-215, miR-133a,miR-467d, miR-218, miR-708, miR-31, and miR-135b in colitis-associated tumors." tissue_expression_ns hsa-mir-150 Psoriasis 21687694 differentially expressed tissue_expression_ns hsa-mir-197 Psoriasis 21687694 differentially expressed tissue_expression_ns hsa-mir-423 Psoriasis 21687694 differentially expressed tissue_expression_ns hsa-mir-1-1 Colorectal Carcinoma 21694772 deregulated tissue_expression_ns hsa-mir-1-2 Colorectal Carcinoma 21694772 deregulated tissue_expression_ns hsa-mir-135a-1 Colorectal Carcinoma 21694772 deregulated tissue_expression_ns hsa-mir-135a-2 Colorectal Carcinoma 21694772 deregulated tissue_expression_ns hsa-mir-135b Colorectal Carcinoma 21694772 deregulated tissue_expression_ns hsa-mir-137 Colorectal Carcinoma 21694772 deregulated tissue_expression_ns hsa-mir-31 Colorectal Carcinoma 21694772 deregulated tissue_expression_ns hsa-mir-9-1 Colorectal Carcinoma 21694772 deregulated tissue_expression_ns hsa-mir-9-2 Colorectal Carcinoma 21694772 deregulated tissue_expression_ns hsa-mir-9-3 Colorectal Carcinoma 21694772 deregulated tissue_expression_ns hsa-mir-99a Colorectal Carcinoma 21694772 deregulated tissue_expression_ns hsa-mir-1 Heart Failure 21737570 "In particular, miRNA-1, miRNA-21, miRNA-24, miRNA-29, miRNA-92a, miRNA-126, miRNA-133, miRNA-320, miRNA-199a, miRNA-208, and miRNA-195 have been shown to be regulated after I/R injury." tissue_expression_ns hsa-mir-126 Heart Failure 21737570 "In particular, miRNA-1, miRNA-21, miRNA-24, miRNA-29, miRNA-92a, miRNA-126, miRNA-133, miRNA-320, miRNA-199a, miRNA-208, and miRNA-195 have been shown to be regulated after I/R injury." tissue_expression_ns hsa-mir-133 Heart Failure 21737570 "In particular, miRNA-1, miRNA-21, miRNA-24, miRNA-29, miRNA-92a, miRNA-126, miRNA-133, miRNA-320, miRNA-199a, miRNA-208, and miRNA-195 have been shown to be regulated after I/R injury." tissue_expression_ns hsa-mir-195 Heart Failure 21737570 "In particular, miRNA-1, miRNA-21, miRNA-24, miRNA-29, miRNA-92a, miRNA-126, miRNA-133, miRNA-320, miRNA-199a, miRNA-208, and miRNA-195 have been shown to be regulated after I/R injury." tissue_expression_ns hsa-mir-199a Heart Failure 21737570 "In particular, miRNA-1, miRNA-21, miRNA-24, miRNA-29, miRNA-92a, miRNA-126, miRNA-133, miRNA-320, miRNA-199a, miRNA-208, and miRNA-195 have been shown to be regulated after I/R injury." tissue_expression_ns hsa-mir-208 Heart Failure 21737570 "In particular, miRNA-1, miRNA-21, miRNA-24, miRNA-29, miRNA-92a, miRNA-126, miRNA-133, miRNA-320, miRNA-199a, miRNA-208, and miRNA-195 have been shown to be regulated after I/R injury." tissue_expression_ns hsa-mir-24 Heart Failure 21737570 "In particular, miRNA-1, miRNA-21, miRNA-24, miRNA-29, miRNA-92a, miRNA-126, miRNA-133, miRNA-320, miRNA-199a, miRNA-208, and miRNA-195 have been shown to be regulated after I/R injury." tissue_expression_ns hsa-mir-29 Heart Failure 21737570 "In particular, miRNA-1, miRNA-21, miRNA-24, miRNA-29, miRNA-92a, miRNA-126, miRNA-133, miRNA-320, miRNA-199a, miRNA-208, and miRNA-195 have been shown to be regulated after I/R injury." tissue_expression_ns hsa-mir-320 Heart Failure 21737570 "In particular, miRNA-1, miRNA-21, miRNA-24, miRNA-29, miRNA-92a, miRNA-126, miRNA-133, miRNA-320, miRNA-199a, miRNA-208, and miRNA-195 have been shown to be regulated after I/R injury." tissue_expression_ns hsa-mir-92a Heart Failure 21737570 "In particular, miRNA-1, miRNA-21, miRNA-24, miRNA-29, miRNA-92a, miRNA-126, miRNA-133, miRNA-320, miRNA-199a, miRNA-208, and miRNA-195 have been shown to be regulated after I/R injury." tissue_expression_ns hsa-mir-216a Fatty Liver [unspecific] 21764575 altered expression tissue_expression_ns hsa-mir-216b Fatty Liver [unspecific] 21764575 altered expression tissue_expression_ns hsa-mir-302a Fatty Liver [unspecific] 21764575 altered expression tissue_expression_ns hsa-mir-146b Thyroid Neoplasms 21778212 "In this context, a small set of miRNAs (i.e. miR-7, miR-146a, miR-146b, miR-200b, miR-221, and miR-222) appears to be useful, though not sufficient per se, in distinguishing TT-UMP from other WDT of the thyroid gland." tissue_expression_ns hsa-mir-200b Thyroid Neoplasms 21778212 "In this context, a small set of miRNAs (i.e. miR-7, miR-146a, miR-146b, miR-200b, miR-221, and miR-222) appears to be useful, though not sufficient per se, in distinguishing TT-UMP from other WDT of the thyroid gland." tissue_expression_ns hsa-mir-221 Thyroid Neoplasms 21778212 "In this context, a small set of miRNAs (i.e. miR-7, miR-146a, miR-146b, miR-200b, miR-221, and miR-222) appears to be useful, though not sufficient per se, in distinguishing TT-UMP from other WDT of the thyroid gland." tissue_expression_ns hsa-mir-222 Thyroid Neoplasms 21778212 "In this context, a small set of miRNAs (i.e. miR-7, miR-146a, miR-146b, miR-200b, miR-221, and miR-222) appears to be useful, though not sufficient per se, in distinguishing TT-UMP from other WDT of the thyroid gland." tissue_expression_ns hsa-mir-7 Thyroid Neoplasms 21778212 "In this context, a small set of miRNAs (i.e. miR-7, miR-146a, miR-146b, miR-200b, miR-221, and miR-222) appears to be useful, though not sufficient per se, in distinguishing TT-UMP from other WDT of the thyroid gland." tissue_expression_ns hsa-mir-100 Pancreatic Neoplasms 21785383 "Differentially expressed miRNAs including miR-99a, miR-100, miR-125b, miR-192, and miR-429 were detected in pancreatic cancer stem cells." tissue_expression_ns hsa-mir-125b-1 Pancreatic Neoplasms 21785383 "Differentially expressed miRNAs including miR-99a, miR-100, miR-125b, miR-192, and miR-429 were detected in pancreatic cancer stem cells." tissue_expression_ns hsa-mir-125b-2 Pancreatic Neoplasms 21785383 "Differentially expressed miRNAs including miR-99a, miR-100, miR-125b, miR-192, and miR-429 were detected in pancreatic cancer stem cells." tissue_expression_ns hsa-mir-192 Pancreatic Neoplasms 21785383 "Differentially expressed miRNAs including miR-99a, miR-100, miR-125b, miR-192, and miR-429 were detected in pancreatic cancer stem cells." tissue_expression_ns hsa-mir-429 Pancreatic Neoplasms 21785383 "Differentially expressed miRNAs including miR-99a, miR-100, miR-125b, miR-192, and miR-429 were detected in pancreatic cancer stem cells." tissue_expression_ns hsa-mir-99a Pancreatic Neoplasms 21785383 "Differentially expressed miRNAs including miR-99a, miR-100, miR-125b, miR-192, and miR-429 were detected in pancreatic cancer stem cells." tissue_expression_ns hsa-mir-135b Osteosarcoma 21789031 deregulated tissue_expression_ns hsa-mir-150 Osteosarcoma 21789031 deregulated tissue_expression_ns hsa-mir-542 Osteosarcoma 21789031 miR-542-5p: deregulated tissue_expression_ns hsa-mir-652 Osteosarcoma 21789031 deregulated tissue_expression_ns hsa-mir-146a Periodontal Diseases 21789961 "hsa-mirNA-146a, hsa-miRNA-146b, and hsa-miRNA-155, showed significant differences between inflamed and healthy gingiva." tissue_expression_ns hsa-mir-146b Periodontal Diseases 21789961 "hsa-mirNA-146a, hsa-miRNA-146b, and hsa-miRNA-155, showed significant differences between inflamed and healthy gingiva." tissue_expression_ns hsa-mir-155 Periodontal Diseases 21789961 "hsa-mirNA-146a, hsa-miRNA-146b, and hsa-miRNA-155, showed significant differences between inflamed and healthy gingiva." tissue_expression_ns hsa-mir-107 Chronic Kidney Disease 21794090 "Differential expression was detected for miR-142-3p, miR-204, miR-107 and miR-211 (p < 0.001) and miR-32 (p < 0.05)." tissue_expression_ns hsa-mir-142 Chronic Kidney Disease 21794090 "Differential expression was detected for miR-142-3p, miR-204, miR-107 and miR-211 (p < 0.001) and miR-32 (p < 0.05). Furthermore, differential expression of miR-142-3p (p < 0.01), miR-204 (p < 0.01) and miR-211 (p < 0.05) was also observed between patient groups in urine samples." tissue_expression_ns hsa-mir-204 Chronic Kidney Disease 21794090 "Differential expression was detected for miR-142-3p, miR-204, miR-107 and miR-211 (p < 0.001) and miR-32 (p < 0.05). Furthermore, differential expression of miR-142-3p (p < 0.01), miR-204 (p < 0.01) and miR-211 (p < 0.05) was also observed between patient groups in urine samples." tissue_expression_ns hsa-mir-211 Chronic Kidney Disease 21794090 "Differential expression was detected for miR-142-3p, miR-204, miR-107 and miR-211 (p < 0.001) and miR-32 (p < 0.05). Furthermore, differential expression of miR-142-3p (p < 0.01), miR-204 (p < 0.01) and miR-211 (p < 0.05) was also observed between patient groups in urine samples." tissue_expression_ns hsa-mir-32 Chronic Kidney Disease 21794090 "Differential expression was detected for miR-142-3p, miR-204, miR-107 and miR-211 (p < 0.001) and miR-32 (p < 0.05)." tissue_expression_ns hsa-mir-100 Psoriasis 21807764 deregulated tissue_expression_ns hsa-mir-142 Psoriasis 21807764 miR-142-3p: deregulated tissue_expression_ns hsa-mir-21 Psoriasis 21807764 deregulated tissue_expression_ns hsa-mir-223 Psoriasis 21807764 miR-223 and miR-223*: deregulated tissue_expression_ns hsa-mir-378a Psoriasis 21807764 deregulated tissue_expression_ns hsa-mir-146b "Carcinoma, Thyroid, Papillary" 21842215 miRNA profiling of hyalinizing trabecular tumours compared with benign thyroid lesions and papillary thyroid carcinoma failed to demonstrate the characteristic up-regulation found in papillary thyroid carcinoma tissue_expression_ns hsa-mir-181b "Carcinoma, Thyroid, Papillary" 21842215 miRNA profiling of hyalinizing trabecular tumours compared with benign thyroid lesions and papillary thyroid carcinoma failed to demonstrate the characteristic up-regulation found in papillary thyroid carcinoma tissue_expression_ns hsa-mir-21 "Carcinoma, Thyroid, Papillary" 21842215 miRNA profiling of hyalinizing trabecular tumours compared with benign thyroid lesions and papillary thyroid carcinoma failed to demonstrate the characteristic up-regulation found in papillary thyroid carcinoma tissue_expression_ns hsa-mir-221 "Carcinoma, Thyroid, Papillary" 21842215 miRNA profiling of hyalinizing trabecular tumours compared with benign thyroid lesions and papillary thyroid carcinoma failed to demonstrate the characteristic up-regulation found in papillary thyroid carcinoma tissue_expression_ns hsa-mir-222 "Carcinoma, Thyroid, Papillary" 21842215 miRNA profiling of hyalinizing trabecular tumours compared with benign thyroid lesions and papillary thyroid carcinoma failed to demonstrate the characteristic up-regulation found in papillary thyroid carcinoma tissue_expression_ns hsa-mir-143 Gastric Neoplasms 21874264 "miR-32,miR-182 and miR-143 dysregulated expression levels are related with different pathological stages of intestinal-type gastric cancers." tissue_expression_ns hsa-mir-145 Gastric Neoplasms 21874264 "miR-145, miR-27a, miR-494 are differently expressed between intestinal-type and diffuse-type gastric cancers." tissue_expression_ns hsa-mir-182 Gastric Neoplasms 21874264 "miR-32,miR-182 and miR-143 dysregulated expression levels are related with different pathological stages of intestinal-type gastric cancers." tissue_expression_ns hsa-mir-27a Gastric Neoplasms 21874264 "miR-145, miR-27a, miR-494 are differently expressed between intestinal-type and diffuse-type gastric cancers." tissue_expression_ns hsa-mir-32 Gastric Neoplasms 21874264 "miR-32,miR-182 and miR-143 dysregulated expression levels are related with different pathological stages of intestinal-type gastric cancers." tissue_expression_ns hsa-mir-494 Gastric Neoplasms 21874264 "miR-145, miR-27a, miR-494 are differently expressed between intestinal-type and diffuse-type gastric cancers." tissue_expression_ns hsa-mir-125b "Carcinoma, Hepatocellular" 21882851 "Many aberrantly expressed miRNAs were related to various cancers (e.g., miR-125b, hepatocellular carcinoma; miR-21, leukemia; miR-16, chronic lymphocytic leukemia;miR-192, pituitary adenomas; miR-199a-3p, ovarian cancer; miR-34a, pancreatic cancer)." tissue_expression_ns hsa-mir-16 "Leukemia, Lymphocytic, Chronic, B-Cell" 21882851 "Many aberrantly expressed miRNAs were related to various cancers (e.g., miR-125b, hepatocellular carcinoma; miR-21, leukemia; miR-16, chronic lymphocytic leukemia;miR-192, pituitary adenomas; miR-199a-3p, ovarian cancer; miR-34a, pancreatic cancer)." tissue_expression_ns hsa-mir-192 Pituitary Adenoma 21882851 "Many aberrantly expressed miRNAs were related to various cancers (e.g., miR-125b, hepatocellular carcinoma; miR-21, leukemia; miR-16, chronic lymphocytic leukemia;miR-192, pituitary adenomas; miR-199a-3p, ovarian cancer; miR-34a, pancreatic cancer)." tissue_expression_ns hsa-mir-199a Ovarian Neoplasms 21882851 "Many aberrantly expressed miRNAs were related to various cancers (e.g., miR-125b, hepatocellular carcinoma; miR-21, leukemia; miR-16, chronic lymphocytic leukemia;miR-192, pituitary adenomas; miR-199a-3p, ovarian cancer; miR-34a, pancreatic cancer)." tissue_expression_ns hsa-mir-21 Leukemia 21882851 "Many aberrantly expressed miRNAs were related to various cancers (e.g., miR-125b, hepatocellular carcinoma; miR-21, leukemia; miR-16, chronic lymphocytic leukemia;miR-192, pituitary adenomas; miR-199a-3p, ovarian cancer; miR-34a, pancreatic cancer)." tissue_expression_ns hsa-mir-34a Pancreatic Neoplasms 21882851 "Many aberrantly expressed miRNAs were related to various cancers (e.g., miR-125b, hepatocellular carcinoma; miR-21, leukemia; miR-16, chronic lymphocytic leukemia;miR-192, pituitary adenomas; miR-199a-3p, ovarian cancer; miR-34a, pancreatic cancer)." tissue_expression_ns hsa-mir-140 "Squamous Cell Carcinoma, Lung" 21890451 "The authors identified a five-microRNA classifier (hsa-miR-210, hsa-miR-182, hsa-miR-486-5p, hsa-miR-30a and hsa-miR-140-3p) that could distinguish SCC (Squamous cell carcinoma) from normal lung tissues." tissue_expression_ns hsa-mir-182 "Squamous Cell Carcinoma, Lung" 21890451 "The authors identified a five-microRNA classifier (hsa-miR-210, hsa-miR-182, hsa-miR-486-5p, hsa-miR-30a and hsa-miR-140-3p) that could distinguish SCC (Squamous cell carcinoma) from normal lung tissues." tissue_expression_ns hsa-mir-210 "Squamous Cell Carcinoma, Lung" 21890451 "The authors identified a five-microRNA classifier (hsa-miR-210, hsa-miR-182, hsa-miR-486-5p, hsa-miR-30a and hsa-miR-140-3p) that could distinguish SCC (Squamous cell carcinoma) from normal lung tissues." tissue_expression_ns hsa-mir-30a "Squamous Cell Carcinoma, Lung" 21890451 "The authors identified a five-microRNA classifier (hsa-miR-210, hsa-miR-182, hsa-miR-486-5p, hsa-miR-30a and hsa-miR-140-3p) that could distinguish SCC (Squamous cell carcinoma) from normal lung tissues." tissue_expression_ns hsa-mir-486 "Squamous Cell Carcinoma, Lung" 21890451 "The authors identified a five-microRNA classifier (hsa-miR-210, hsa-miR-182, hsa-miR-486-5p, hsa-miR-30a and hsa-miR-140-3p) that could distinguish SCC (Squamous cell carcinoma) from normal lung tissues." tissue_expression_ns hsa-mir-10a Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-125b-1 Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-125b-2 Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-181a-2 Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-181b-1 Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-181b-2 Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-200a Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-200b Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-200c Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-205 Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-21 Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-22 Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-222 Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells tissue_expression_ns hsa-mir-29a Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-93 Breast Neoplasms 21955614 Differential expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. tissue_expression_ns hsa-mir-21 Myocardial Infarction 21956146 deregulated tissue_expression_ns hsa-mir-29a Myocardial Infarction 21956146 deregulated tissue_expression_ns hsa-mir-196a Breast Neoplasms 21962133 miR-196a has been reported to be aberrantly expressed in breast cancer tissue. tissue_expression_ns hsa-mir-125a Gastric Neoplasms 21987613 "Five microRNAs (miR-125a-3p, miR-133b, miR-143, miR-195 and miR-212) were differently expressed between different metastatic groups in 30 gastric cancer biopsies (P < 0.05). Partial correlation analysis showed that hsa-mir-212 and hsa-mir-195 were correlated with the status of metastasis to LN in spite of age, gender, tumor location, tumor size, depth of invasion and cell differentiation. ROC analysis indicated that miR-212 and miR-195 have better sensitivities (84.6% and 69.2%, respectively) and specificities (both 100%) in distinguishing biopsies with metastasis to LN from biopsies without metastasis to LN." tissue_expression_ns hsa-mir-133b Gastric Neoplasms 21987613 "Five microRNAs (miR-125a-3p, miR-133b, miR-143, miR-195 and miR-212) were differently expressed between different metastatic groups in 30 gastric cancer biopsies (P < 0.05). Partial correlation analysis showed that hsa-mir-212 and hsa-mir-195 were correlated with the status of metastasis to LN in spite of age, gender, tumor location, tumor size, depth of invasion and cell differentiation. ROC analysis indicated that miR-212 and miR-195 have better sensitivities (84.6% and 69.2%, respectively) and specificities (both 100%) in distinguishing biopsies with metastasis to LN from biopsies without metastasis to LN." tissue_expression_ns hsa-mir-143 Gastric Neoplasms 21987613 "Five microRNAs (miR-125a-3p, miR-133b, miR-143, miR-195 and miR-212) were differently expressed between different metastatic groups in 30 gastric cancer biopsies (P < 0.05). Partial correlation analysis showed that hsa-mir-212 and hsa-mir-195 were correlated with the status of metastasis to LN in spite of age, gender, tumor location, tumor size, depth of invasion and cell differentiation. ROC analysis indicated that miR-212 and miR-195 have better sensitivities (84.6% and 69.2%, respectively) and specificities (both 100%) in distinguishing biopsies with metastasis to LN from biopsies without metastasis to LN." tissue_expression_ns hsa-mir-195 Gastric Neoplasms 21987613 "Five microRNAs (miR-125a-3p, miR-133b, miR-143, miR-195 and miR-212) were differently expressed between different metastatic groups in 30 gastric cancer biopsies (P < 0.05). Partial correlation analysis showed that hsa-mir-212 and hsa-mir-195 were correlated with the status of metastasis to LN in spite of age, gender, tumor location, tumor size, depth of invasion and cell differentiation. ROC analysis indicated that miR-212 and miR-195 have better sensitivities (84.6% and 69.2%, respectively) and specificities (both 100%) in distinguishing biopsies with metastasis to LN from biopsies without metastasis to LN." tissue_expression_ns hsa-mir-212 Gastric Neoplasms 21987613 "Five microRNAs (miR-125a-3p, miR-133b, miR-143, miR-195 and miR-212) were differently expressed between different metastatic groups in 30 gastric cancer biopsies (P < 0.05). Partial correlation analysis showed that hsa-mir-212 and hsa-mir-195 were correlated with the status of metastasis to LN in spite of age, gender, tumor location, tumor size, depth of invasion and cell differentiation. ROC analysis indicated that miR-212 and miR-195 have better sensitivities (84.6% and 69.2%, respectively) and specificities (both 100%) in distinguishing biopsies with metastasis to LN from biopsies without metastasis to LN." tissue_expression_ns hsa-mir-130b "Tuberculosis, Pulmonary" 22003408 hsa-mir-130b*: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-144 "Tuberculosis, Pulmonary" 22003408 hsa-mir-144: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-155 "Tuberculosis, Pulmonary" 22003408 hsa-mir-155: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-181b-1 "Tuberculosis, Pulmonary" 22003408 hsa-mir-181b: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-181b-2 "Tuberculosis, Pulmonary" 22003408 hsa-mir-181b: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-21 "Tuberculosis, Pulmonary" 22003408 hsa-mir-21*: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-223 "Tuberculosis, Pulmonary" 22003408 hsa-mir-223: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-302a "Tuberculosis, Pulmonary" 22003408 hsa-mir-302a: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-329-1 "Tuberculosis, Pulmonary" 22003408 hsa-mir-329: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-329-2 "Tuberculosis, Pulmonary" 22003408 hsa-mir-329: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-342 "Tuberculosis, Pulmonary" 22003408 hsa-mir-342-5p: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-421 "Tuberculosis, Pulmonary" 22003408 hsa-mir-421: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-424 "Tuberculosis, Pulmonary" 22003408 hsa-mir-424: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-451a "Tuberculosis, Pulmonary" 22003408 hsa-mir-451: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-486 "Tuberculosis, Pulmonary" 22003408 hsa-mir-486-5p: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-520d "Tuberculosis, Pulmonary" 22003408 hsa-mir-520d-3p: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-548b "Tuberculosis, Pulmonary" 22003408 hsa-mir-548b-3p: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-550a-1 "Tuberculosis, Pulmonary" 22003408 hsa-mir-550*: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-550a-2 "Tuberculosis, Pulmonary" 22003408 hsa-mir-550*: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-550a-3 "Tuberculosis, Pulmonary" 22003408 hsa-mir-550*: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-550b-1 "Tuberculosis, Pulmonary" 22003408 hsa-mir-550*: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-550b-2 "Tuberculosis, Pulmonary" 22003408 hsa-mir-550*: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-640 "Tuberculosis, Pulmonary" 22003408 hsa-mir-640: differently expressed in the samples from study participants with active tuberculosis (TB) versus latent tuberculosis infection (LTBI). tissue_expression_ns hsa-mir-516a-1 Frontotemporal Lobar Degeneration 22032330 miR-516a-3p was significantly dysregulated in frontal cortex and cerebellar tissue samples of PGRN mutation carriers. tissue_expression_ns hsa-mir-516a-2 Frontotemporal Lobar Degeneration 22032330 miR-516a-3p was significantly dysregulated in frontal cortex and cerebellar tissue samples of PGRN mutation carriers. tissue_expression_ns hsa-mir-548b Frontotemporal Lobar Degeneration 22032330 miR-548b-5p was significantly dysregulated in frontal cortex and cerebellar tissue samples of PGRN mutation carriers. tissue_expression_ns hsa-mir-548c Frontotemporal Lobar Degeneration 22032330 miR-548c-5p was significantly dysregulated in frontal cortex and cerebellar tissue samples of PGRN mutation carriers. tissue_expression_ns hsa-mir-571 Frontotemporal Lobar Degeneration 22032330 miR-571 was significantly dysregulated in frontal cortex and cerebellar tissue samples of PGRN mutation carriers. tissue_expression_ns hsa-mir-922 Frontotemporal Lobar Degeneration 22032330 miR-922 was significantly dysregulated in frontal cortex and cerebellar tissue samples of PGRN mutation carriers. tissue_expression_ns hsa-mir-126 "Carcinoma, Renal Cell" 22033272 The expression level of this miRNA was significantly altered in two independent cohorts of patients. tissue_expression_ns hsa-mir-196a-1 "Carcinoma, Renal Cell" 22033272 The expression level of this miRNA was significantly altered in two independent cohorts of patients. tissue_expression_ns hsa-mir-204 "Carcinoma, Renal Cell" 22033272 The expression level of this miRNA was significantly altered in two independent cohorts of patients. tissue_expression_ns hsa-mir-215 "Carcinoma, Renal Cell" 22033272 "The expression level of this miRNA was significantly altered in two independent cohorts of patients. Overexpression of miR-215 decreased cellular migration and invasion in an RCC cell line model. In addition, through gene expression profiling, the authors identified direct and indirect targets of miR-215 that can contribute to tumour metastasis." tissue_expression_ns hsa-mir-124-1 Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-124-2 Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-124-3 Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-132 Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-146a Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-155 Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-15a Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-16-1 Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-16-2 Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-203 Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-223 Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-346 Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-363 Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-mir-498 Rheumatoid Arthritis 22100329 deregulated tissue_expression_ns hsa-let-7f-1 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-let-7f-2 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-let-7g Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-1-1 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-1-2 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-122 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-127 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-128-1 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-128-2 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-130a Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-132 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-140 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-146a Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-146b Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-155 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-16-1 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-16-2 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-181b-1 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-181b-2 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-182 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-183 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-185 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-186 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-193b Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-195 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-199b Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-206 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-223 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-224 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-26b Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-320a Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-328 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-340 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-342 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-34c Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-363 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-374a Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-374b Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-421 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-487b Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-497 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-503 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-513a-1 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-513a-2 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-513b Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-513c Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-515-1 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-515-2 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-516a-1 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-516a-2 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-516b-1 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-516b-2 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-517a Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-518f Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-519a-1 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-519a-2 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-519c Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-519e Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-520a Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-520d Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-524 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-526a-1 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-526a-2 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-577 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-591 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-595 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-601 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-629 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-640 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-658 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-661 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemoresistance tissue_expression_ns hsa-mir-95 Gastric Neoplasms 22112324 A miRNA signature distinguishing gastric cancer from normal stomach epithelium was identified. 30 miRNAs were significantly inversely correlated with TTP whereas 28 miRNAs were significantly positively correlated with TTP of 82 cancer patients (P<0.05). This miRNA is associated with chemosensitivity tissue_expression_ns hsa-mir-125b-1 Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-125b-2 Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-146a Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-155 Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-182 Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-183 Pancreatic Neoplasms 22114139 miR-183*:altered expression tissue_expression_ns hsa-mir-196b Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-200a Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-200b Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-200c Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-203 Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-21 Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-216a Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-216b Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-217 Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-222 Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-296 Pancreatic Neoplasms 22114139 miR-296-5p:altered expression tissue_expression_ns hsa-mir-338 Pancreatic Neoplasms 22114139 miR-338-3p;altered expression tissue_expression_ns hsa-mir-486 Pancreatic Neoplasms 22114139 miR-486-3p:altered expression tissue_expression_ns hsa-mir-603 Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-625 Pancreatic Neoplasms 22114139 miR-625*:altered expression tissue_expression_ns hsa-mir-708 Pancreatic Neoplasms 22114139 altered expression tissue_expression_ns hsa-mir-10a Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-1-1 Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-1-2 Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-125b-1 Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-125b-2 Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-133a-1 Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-133a-2 Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-133b Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-143 Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-145 Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-182 Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-183 Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-203 Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-224 Urinary Bladder Cancer 22140553 deregulated tissue_expression_ns hsa-mir-1-1 Prostate Neoplasms 22210864 MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer. tissue_expression_ns hsa-mir-1-2 Prostate Neoplasms 22210864 MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer. tissue_expression_ns hsa-let-7b Breast Neoplasms 22294324 "let-7b expression was shown to be associated with luminal tumours, and to have an independent significant positive prognostic value in this group. miR-205 is associated with tumours of ductal morphology, and is of significant positive prognostic value within these tumours." tissue_expression_ns hsa-mir-205 Breast Neoplasms 22294324 "let-7b expression was shown to be associated with luminal tumours, and to have an independent significant positive prognostic value in this group. miR-205 is associated with tumours of ductal morphology, and is of significant positive prognostic value within these tumours." tissue_expression_ns hsa-mir-146a Lupus Nephritis 22295894 "Intra-renal expression of miR-638, miR-198 and miR-146a are differentially expressed between LN patients and normal controls. Furthermore, the degree of change in glomerular miR-146a and tubulointerstitial miR-638 expression correlated with clinical disease severity." tissue_expression_ns hsa-mir-198 Lupus Nephritis 22295894 "Intra-renal expression of miR-638, miR-198 and miR-146a are differentially expressed between LN patients and normal controls. Furthermore, the degree of change in glomerular miR-146a and tubulointerstitial miR-638 expression correlated with clinical disease severity." tissue_expression_ns hsa-mir-638 Lupus Nephritis 22295894 "Intra-renal expression of miR-638, miR-198 and miR-146a are differentially expressed between LN patients and normal controls. Furthermore, the degree of change in glomerular miR-146a and tubulointerstitial miR-638 expression correlated with clinical disease severity." tissue_expression_ns hsa-mir-145 "Scleroderma, Systemic" 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis tissue_expression_ns hsa-mir-146a "Scleroderma, Systemic" 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis tissue_expression_ns hsa-mir-146b "Scleroderma, Systemic" 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis tissue_expression_ns hsa-mir-21 "Scleroderma, Systemic" 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis tissue_expression_ns hsa-mir-29b-1 "Scleroderma, Systemic" 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis tissue_expression_ns hsa-mir-29b-2 "Scleroderma, Systemic" 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis tissue_expression_ns hsa-mir-31 "Scleroderma, Systemic" 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis tissue_expression_ns hsa-mir-503 "Scleroderma, Systemic" 22307526 The expression of the miRNA was correlated with Systemic Scleroderma fibrosis tissue_expression_ns hsa-let-7i Breast Neoplasms 22315424 "Five noncoding genes were associated with both prognostic signatures-miR-210, -21, -106b*, -197, and let-7i, with miR-210 the only one also involved in the invasive transition." tissue_expression_ns hsa-mir-106b Breast Neoplasms 22315424 "Five noncoding genes were associated with both prognostic signatures-miR-210, -21, -106b*, -197, and let-7i, with miR-210 the only one also involved in the invasive transition." tissue_expression_ns hsa-mir-197 Breast Neoplasms 22315424 "Five noncoding genes were associated with both prognostic signatures-miR-210, -21, -106b*, -197, and let-7i, with miR-210 the only one also involved in the invasive transition." tissue_expression_ns hsa-mir-21 Breast Neoplasms 22315424 "Five noncoding genes were associated with both prognostic signatures-miR-210, -21, -106b*, -197, and let-7i, with miR-210 the only one also involved in the invasive transition." tissue_expression_ns hsa-mir-10b "Carcinoma, Oral" 22318752 hsa-mir-10b has the potential for Oncogenic Function and Early Detection in Oral Cancer as Identified by microRNA Profiling. tissue_expression_ns hsa-mir-100 Urinary Bladder Cancer 22330141 "Altered expression of five significantly differentially expressed miRNAs, hsa-miR-9 (1q23.2), hsa-miR-15b (3q25.32), hsa-miR-28-5p (3q27.3), hsa-miR-100 and hsa-miR-125b (both 11q24.1), was directly linked to frequent chromosomal alterations." tissue_expression_ns hsa-mir-125b-1 Urinary Bladder Cancer 22330141 "Altered expression of five significantly differentially expressed miRNAs, hsa-miR-9 (1q23.2), hsa-miR-15b (3q25.32), hsa-miR-28-5p (3q27.3), hsa-miR-100 and hsa-miR-125b (both 11q24.1), was directly linked to frequent chromosomal alterations." tissue_expression_ns hsa-mir-15b Urinary Bladder Cancer 22330141 "Altered expression of five significantly differentially expressed miRNAs, hsa-miR-9 (1q23.2), hsa-miR-15b (3q25.32), hsa-miR-28-5p (3q27.3), hsa-miR-100 and hsa-miR-125b (both 11q24.1), was directly linked to frequent chromosomal alterations." tissue_expression_ns hsa-mir-28 Urinary Bladder Cancer 22330141 "Altered expression of five significantly differentially expressed miRNAs, hsa-miR-9 (1q23.2), hsa-miR-15b (3q25.32), hsa-miR-28-5p (3q27.3), hsa-miR-100 and hsa-miR-125b (both 11q24.1), was directly linked to frequent chromosomal alterations." tissue_expression_ns hsa-mir-9-1 Urinary Bladder Cancer 22330141 "Altered expression of five significantly differentially expressed miRNAs, hsa-miR-9 (1q23.2), hsa-miR-15b (3q25.32), hsa-miR-28-5p (3q27.3), hsa-miR-100 and hsa-miR-125b (both 11q24.1), was directly linked to frequent chromosomal alterations." tissue_expression_ns hsa-mir-15b "Carcinoma, Lung, Non-Small-Cell" 22389695 "A combination of two differentially expressed miRNAs miR-15b and miR-27b, was able to discriminate NSCLC from healthy controls with sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 100% in the training set." tissue_expression_ns hsa-mir-27b "Carcinoma, Lung, Non-Small-Cell" 22389695 "A combination of two differentially expressed miRNAs miR-15b and miR-27b, was able to discriminate NSCLC from healthy controls with sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 100% in the training set." tissue_expression_ns hsa-mir-124-1 Lymphoma 22395483 "A distinct set of five microRNAs (miR-150, miR-550, miR-124a, miR-518b and miR-539) was shown to be differentially expressed in gastritis as opposed to MALT lymphoma." tissue_expression_ns hsa-mir-150 Lymphoma 22395483 "A distinct set of five microRNAs (miR-150, miR-550, miR-124a, miR-518b and miR-539) was shown to be differentially expressed in gastritis as opposed to MALT lymphoma." tissue_expression_ns hsa-mir-518b Lymphoma 22395483 "A distinct set of five microRNAs (miR-150, miR-550, miR-124a, miR-518b and miR-539) was shown to be differentially expressed in gastritis as opposed to MALT lymphoma." tissue_expression_ns hsa-mir-539 Lymphoma 22395483 "A distinct set of five microRNAs (miR-150, miR-550, miR-124a, miR-518b and miR-539) was shown to be differentially expressed in gastritis as opposed to MALT lymphoma." tissue_expression_ns hsa-mir-550a-1 Lymphoma 22395483 "A distinct set of five microRNAs (miR-150, miR-550, miR-124a, miR-518b and miR-539) was shown to be differentially expressed in gastritis as opposed to MALT lymphoma." tissue_expression_ns hsa-mir-550a-2 Lymphoma 22395483 "A distinct set of five microRNAs (miR-150, miR-550, miR-124a, miR-518b and miR-539) was shown to be differentially expressed in gastritis as opposed to MALT lymphoma." tissue_expression_ns hsa-mir-143 Urinary Bladder Cancer 22426337 "miR-143, miR-222, and miR-452 Are Useful as Tumor Stratification and Noninvasive Diagnostic Biomarkers for Bladder Cancer." tissue_expression_ns hsa-mir-222 Urinary Bladder Cancer 22426337 "miR-143, miR-222, and miR-452 Are Useful as Tumor Stratification and Noninvasive Diagnostic Biomarkers for Bladder Cancer." tissue_expression_ns hsa-mir-452 Urinary Bladder Cancer 22426337 "miR-143, miR-222, and miR-452 Are Useful as Tumor Stratification and Noninvasive Diagnostic Biomarkers for Bladder Cancer." tissue_expression_ns hsa-mir-199b Heart Failure 22427379 "Six miRNAs were differently expressed when comparing D-HF (diabetic HF) and ND-HF (nondiabetic HF) patients: miR-34b, miR-34c, miR-199b, miR-210, miR-650, and miR-223." tissue_expression_ns hsa-mir-210 Heart Failure 22427379 "Six miRNAs were differently expressed when comparing D-HF (diabetic HF) and ND-HF (nondiabetic HF) patients: miR-34b, miR-34c, miR-199b, miR-210, miR-650, and miR-223." tissue_expression_ns hsa-mir-223 Heart Failure 22427379 "Six miRNAs were differently expressed when comparing D-HF (diabetic HF) and ND-HF (nondiabetic HF) patients: miR-34b, miR-34c, miR-199b, miR-210, miR-650, and miR-223." tissue_expression_ns hsa-mir-34b Heart Failure 22427379 "Six miRNAs were differently expressed when comparing D-HF (diabetic HF) and ND-HF (nondiabetic HF) patients: miR-34b, miR-34c, miR-199b, miR-210, miR-650, and miR-223." tissue_expression_ns hsa-mir-34c Heart Failure 22427379 "Six miRNAs were differently expressed when comparing D-HF (diabetic HF) and ND-HF (nondiabetic HF) patients: miR-34b, miR-34c, miR-199b, miR-210, miR-650, and miR-223." tissue_expression_ns hsa-mir-650 Heart Failure 22427379 "Six miRNAs were differently expressed when comparing D-HF (diabetic HF) and ND-HF (nondiabetic HF) patients: miR-34b, miR-34c, miR-199b, miR-210, miR-650, and miR-223." tissue_expression_ns hsa-mir-106b Ewing Sarcoma 22429812 "MiR-21, miR-31, miR-31*, miR-106b, miR-145, miR-150*, miR-371-5p, miR-557 and miR-598 showed recurrently altered expression." tissue_expression_ns hsa-mir-145 Ewing Sarcoma 22429812 "MiR-21, miR-31, miR-31*, miR-106b, miR-145, miR-150*, miR-371-5p, miR-557 and miR-598 showed recurrently altered expression." tissue_expression_ns hsa-mir-150 Ewing Sarcoma 22429812 "MiR-21, miR-31, miR-31*, miR-106b, miR-145, miR-150*, miR-371-5p, miR-557 and miR-598 showed recurrently altered expression." tissue_expression_ns hsa-mir-21 Ewing Sarcoma 22429812 "MiR-21, miR-31, miR-31*, miR-106b, miR-145, miR-150*, miR-371-5p, miR-557 and miR-598 showed recurrently altered expression." tissue_expression_ns hsa-mir-31 Ewing Sarcoma 22429812 "MiR-21, miR-31, miR-31*, miR-106b, miR-145, miR-150*, miR-371-5p, miR-557 and miR-598 showed recurrently altered expression." tissue_expression_ns hsa-mir-371a Ewing Sarcoma 22429812 "MiR-21, miR-31, miR-31*, miR-106b, miR-145, miR-150*, miR-371-5p, miR-557 and miR-598 showed recurrently altered expression." tissue_expression_ns hsa-mir-557 Ewing Sarcoma 22429812 "MiR-21, miR-31, miR-31*, miR-106b, miR-145, miR-150*, miR-371-5p, miR-557 and miR-598 showed recurrently altered expression." tissue_expression_ns hsa-mir-598 Ewing Sarcoma 22429812 "MiR-21, miR-31, miR-31*, miR-106b, miR-145, miR-150*, miR-371-5p, miR-557 and miR-598 showed recurrently altered expression." tissue_expression_ns hsa-mir-137 Leiomyoma 22446413 deregulated tissue_expression_ns hsa-mir-217 Leiomyoma 22446413 deregulated tissue_expression_ns hsa-mir-363 Leiomyoma 22446413 deregulated tissue_expression_ns hsa-mir-4792 Leiomyoma 22446413 deregulated tissue_expression_ns hsa-mir-490 Leiomyoma 22446413 deregulated tissue_expression_ns hsa-mir-135a-1 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma tissue_expression_ns hsa-mir-135a-2 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma tissue_expression_ns hsa-mir-150 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma tissue_expression_ns hsa-mir-184 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma tissue_expression_ns hsa-mir-342 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma tissue_expression_ns hsa-mir-363 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma tissue_expression_ns hsa-mir-708 Lymphoma 22490335 different expression between small lymphocytic leukemia and lymphoma tissue_expression_ns hsa-mir-103 Lung Neoplasms 22576802 "Among them, some have a well-characterized association with cancer progression, e.g. miR-125b, miR-210, miR-103, miR-194 and miR-500. In summary, it is evident from our results that MTA1 functions in regulating the invasive phenotype of lung cancer cells and this regulation may be through altered miRNA expression." tissue_expression_ns hsa-mir-125b Lung Neoplasms 22576802 "Among them, some have a well-characterized association with cancer progression, e.g. miR-125b, miR-210, miR-103, miR-194 and miR-500. In summary, it is evident from our results that MTA1 functions in regulating the invasive phenotype of lung cancer cells and this regulation may be through altered miRNA expression." tissue_expression_ns hsa-mir-194 Lung Neoplasms 22576802 "Among them, some have a well-characterized association with cancer progression, e.g. miR-125b, miR-210, miR-103, miR-194 and miR-500. In summary, it is evident from our results that MTA1 functions in regulating the invasive phenotype of lung cancer cells and this regulation may be through altered miRNA expression." tissue_expression_ns hsa-mir-210 Lung Neoplasms 22576802 "Among them, some have a well-characterized association with cancer progression, e.g. miR-125b, miR-210, miR-103, miR-194 and miR-500. In summary, it is evident from our results that MTA1 functions in regulating the invasive phenotype of lung cancer cells and this regulation may be through altered miRNA expression." tissue_expression_ns hsa-mir-500 Lung Neoplasms 22576802 "Among them, some have a well-characterized association with cancer progression, e.g. miR-125b, miR-210, miR-103, miR-194 and miR-500. In summary, it is evident from our results that MTA1 functions in regulating the invasive phenotype of lung cancer cells and this regulation may be through altered miRNA expression." tissue_expression_ns hsa-mir-182 "Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic" 22582938 Aberrant microRNA-182 expression is associated with glucocorticoid resistance in lymphoblastic malignancies. tissue_expression_ns hsa-mir-10b "Carcinoma, Renal Cell" 22623952 "The expression levels of miR-10b, miR-139-5p, miR-130b and miR-199b-5p could determine the status of ccRCC metastasis." tissue_expression_ns hsa-mir-130b "Carcinoma, Renal Cell" 22623952 "The expression levels of miR-10b, miR-139-5p, miR-130b and miR-199b-5p could determine the status of ccRCC metastasis." tissue_expression_ns hsa-mir-139 "Carcinoma, Renal Cell" 22623952 "The expression levels of miR-10b, miR-139-5p, miR-130b and miR-199b-5p could determine the status of ccRCC metastasis." tissue_expression_ns hsa-mir-195 "Carcinoma, Renal Cell" 22623952 "The expression levels of miR-10b, miR-139-5p, miR-130b and miR-199b-5p could determine the status of ccRCC metastasis." tissue_expression_ns hsa-mir-199b "Carcinoma, Renal Cell" 22623952 "The expression levels of miR-10b, miR-139-5p, miR-130b and miR-199b-5p could determine the status of ccRCC metastasis." tissue_expression_ns hsa-mir-205 Breast Neoplasms 22631664 miR-205 and miR-342 may be used as potential biomarkers for diagnosis of triple negative breast cancer. tissue_expression_ns hsa-mir-342 Breast Neoplasms 22631664 miR-205 and miR-342 may be used as potential biomarkers for diagnosis of triple negative breast cancer. tissue_expression_ns hsa-mir-100 Urinary Bladder Cancer 22644299 differential expression in urinary samples tissue_expression_ns hsa-mir-1224 Urinary Bladder Cancer 22644299 differential expression in urinary samples tissue_expression_ns hsa-mir-135b Urinary Bladder Cancer 22644299 differential expression in urinary samples tissue_expression_ns hsa-mir-15a Urinary Bladder Cancer 22644299 differential expression in urinary samples tissue_expression_ns hsa-mir-15b Urinary Bladder Cancer 22644299 differential expression in urinary samples tissue_expression_ns hsa-mir-203 Urinary Bladder Cancer 22644299 differential expression in urinary samples tissue_expression_ns hsa-mir-212 Urinary Bladder Cancer 22644299 differential expression in urinary samples tissue_expression_ns hsa-mir-24-1 Urinary Bladder Cancer 22644299 differential expression in urinary samples tissue_expression_ns hsa-mir-27b Urinary Bladder Cancer 22644299 differential expression in urinary samples tissue_expression_ns hsa-mir-328 Urinary Bladder Cancer 22644299 differential expression in urinary samples tissue_expression_ns hsa-mir-574 Gastric Neoplasms 22683180 miR-574-3p: Aberrant expression tissue_expression_ns hsa-mir-125a Head And Neck Neoplasms 22690848 Differential expression tissue_expression_ns hsa-mir-125b-1 Head And Neck Neoplasms 22690848 Differential expression tissue_expression_ns hsa-mir-125b-2 Head And Neck Neoplasms 22690848 Differential expression tissue_expression_ns hsa-mir-203 Head And Neck Neoplasms 22690848 Differential expression tissue_expression_ns hsa-mir-21 Head And Neck Neoplasms 22690848 Differential expression tissue_expression_ns hsa-mir-31 Head And Neck Neoplasms 22690848 Differential expression tissue_expression_ns hsa-mir-199a "Carcinoma, Hepatocellular" 22714032 "the expression of miR-21, miR-221, miR-222 and miR-199a showing characteristic alterations in hepatocellular carcinoma also displayed deregulated expressions in these two early stages." tissue_expression_ns hsa-mir-21 "Carcinoma, Hepatocellular" 22714032 "the expression of miR-21, miR-221, miR-222 and miR-199a showing characteristic alterations in hepatocellular carcinoma also displayed deregulated expressions in these two early stages." tissue_expression_ns hsa-mir-221 "Carcinoma, Hepatocellular" 22714032 "the expression of miR-21, miR-221, miR-222 and miR-199a showing characteristic alterations in hepatocellular carcinoma also displayed deregulated expressions in these two early stages." tissue_expression_ns hsa-mir-222 "Carcinoma, Hepatocellular" 22714032 "the expression of miR-21, miR-221, miR-222 and miR-199a showing characteristic alterations in hepatocellular carcinoma also displayed deregulated expressions in these two early stages." tissue_expression_ns hsa-mir-155 Lymphoma 22776000 "Although miRNA microarray analysis did not identify statistically significant differentially expressed miRNAs, miRNA-Q-PCR demonstrated statistically significantly differential expression of miR-155, miR-27b, miR-93, miR-29b and miR-92a between tumor-stage MF and C-ALCL." tissue_expression_ns hsa-mir-27b Lymphoma 22776000 "Although miRNA microarray analysis did not identify statistically significant differentially expressed miRNAs, miRNA-Q-PCR demonstrated statistically significantly differential expression of miR-155, miR-27b, miR-93, miR-29b and miR-92a between tumor-stage MF and C-ALCL." tissue_expression_ns hsa-mir-29b Lymphoma 22776000 "Although miRNA microarray analysis did not identify statistically significant differentially expressed miRNAs, miRNA-Q-PCR demonstrated statistically significantly differential expression of miR-155, miR-27b, miR-93, miR-29b and miR-92a between tumor-stage MF and C-ALCL." tissue_expression_ns hsa-mir-92a Lymphoma 22776000 "Although miRNA microarray analysis did not identify statistically significant differentially expressed miRNAs, miRNA-Q-PCR demonstrated statistically significantly differential expression of miR-155, miR-27b, miR-93, miR-29b and miR-92a between tumor-stage MF and C-ALCL." tissue_expression_ns hsa-mir-93 Lymphoma 22776000 "Although miRNA microarray analysis did not identify statistically significant differentially expressed miRNAs, miRNA-Q-PCR demonstrated statistically significantly differential expression of miR-155, miR-27b, miR-93, miR-29b and miR-92a between tumor-stage MF and C-ALCL." tissue_expression_ns hsa-mir-10a Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-193b Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-203 Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-20b Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-338 Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-345 Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-34b Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-34c Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-424 Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-512-1 Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-512-2 Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-518a-1 Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-518a-2 Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-9-1 Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-9-2 Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-9-3 Urinary Bladder Cancer 22801550 differentially expressed tissue_expression_ns hsa-mir-143 Pancreatic Neoplasms 22836856 Changes in miR-143 and miR-21 Expression are correlated with Clinicopathology in Pancreatic Cancers. tissue_expression_ns hsa-mir-21 Pancreatic Neoplasms 22836856 Changes in miR-143 and miR-21 Expression are correlated with Clinicopathology in Pancreatic Cancers. tissue_expression_ns hsa-mir-128-1 Glioblastoma 22844109 "Expression of miR-128a, -504, -124a, and -184 each negatively correlated with the expression of mesenchymal markers in GBM." tissue_expression_ns hsa-mir-128-2 Glioblastoma 22844109 "Expression of miR-128a, -504, -124a, and -184 each negatively correlated with the expression of mesenchymal markers in GBM." tissue_expression_ns hsa-mir-184 Glioblastoma 22844109 "Expression of miR-128a, -504, -124a, and -184 each negatively correlated with the expression of mesenchymal markers in GBM." tissue_expression_ns hsa-mir-504 Glioblastoma 22844109 "Expression of miR-128a, -504, -124a, and -184 each negatively correlated with the expression of mesenchymal markers in GBM." tissue_expression_ns hsa-mir-135b Colorectal Carcinoma 22844381 "Expression of miR-21, miR-31, miR-96 and miR-135b is correlated with the clinical parameters of colorectal cancer." tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 22844381 "Expression of miR-21, miR-31, miR-96 and miR-135b is correlated with the clinical parameters of colorectal cancer." tissue_expression_ns hsa-mir-31 Colorectal Carcinoma 22844381 "Expression of miR-21, miR-31, miR-96 and miR-135b is correlated with the clinical parameters of colorectal cancer." tissue_expression_ns hsa-mir-96 Colorectal Carcinoma 22844381 "Expression of miR-21, miR-31, miR-96 and miR-135b is correlated with the clinical parameters of colorectal cancer." tissue_expression_ns hsa-mir-144 Colorectal Carcinoma 22850566 differentially expressed tissue_expression_ns hsa-mir-147b Colorectal Carcinoma 22850566 differentially expressed tissue_expression_ns hsa-mir-148a Colorectal Carcinoma 22850566 differentially expressed tissue_expression_ns hsa-mir-190a Colorectal Carcinoma 22850566 differentially expressed tissue_expression_ns hsa-mir-2110 Colorectal Carcinoma 22850566 differentially expressed tissue_expression_ns hsa-mir-26a-1 Colorectal Carcinoma 22850566 differentially expressed tissue_expression_ns hsa-mir-26a-2 Colorectal Carcinoma 22850566 differentially expressed tissue_expression_ns hsa-mir-26b Colorectal Carcinoma 22850566 differentially expressed tissue_expression_ns hsa-mir-338 Colorectal Carcinoma 22850566 miR-338-3p: differentially expressed tissue_expression_ns hsa-mir-375 Colorectal Carcinoma 22850566 differentially expressed tissue_expression_ns hsa-mir-483 Colorectal Carcinoma 22850566 miR-483-5p: differentially expressed tissue_expression_ns hsa-mir-492 Colorectal Carcinoma 22850566 differentially expressed tissue_expression_ns hsa-mir-542 Colorectal Carcinoma 22850566 miR-542-5p: differentially expressed tissue_expression_ns hsa-mir-584 Colorectal Carcinoma 22850566 differentially expressed tissue_expression_ns hsa-mir-652 Colorectal Carcinoma 22850566 differentially expressed tissue_expression_ns hsa-mir-183 Esophageal Neoplasms 22891887 "The relative expressions of miR-155, miR-183, and miR-20a in esophageal tissue were found to be significantly associated with increased risk for esophageal cancer." tissue_expression_ns hsa-mir-20a Esophageal Neoplasms 22891887 "The relative expressions of miR-155, miR-183, and miR-20a in esophageal tissue were found to be significantly associated with increased risk for esophageal cancer." tissue_expression_ns hsa-mir-106a Inflammatory Bowel Diseases 22899284 "A significant difference in expressions of miR-19b, miR-106a, and miR-629 was detected between ulcerative colitis and Crohns disease groups (P<0.05)." tissue_expression_ns hsa-mir-19b-1 Inflammatory Bowel Diseases 22899284 "A significant difference in expressions of miR-19b, miR-106a, and miR-629 was detected between ulcerative colitis and Crohns disease groups (P<0.05)." tissue_expression_ns hsa-mir-19b-2 Inflammatory Bowel Diseases 22899284 "A significant difference in expressions of miR-19b, miR-106a, and miR-629 was detected between ulcerative colitis and Crohns disease groups (P<0.05)." tissue_expression_ns hsa-mir-629 Inflammatory Bowel Diseases 22899284 "A significant difference in expressions of miR-19b, miR-106a, and miR-629 was detected between ulcerative colitis and Crohns disease groups (P<0.05)." tissue_expression_ns hsa-mir-181d Ovarian Neoplasms 22925189 "Expression of four miRNAs (miR-30c, miR-30d, miR-30e-3p, miR-370) was significantly different between carcinomas and benign ovarian tissues as well as between carcinoma and borderline tissues. An additional three miRNAs (miR-181d, miR-30a-3p, miR-532-5p) were significantly different between borderline and carcinoma tissues." tissue_expression_ns hsa-mir-30a Ovarian Neoplasms 22925189 "Expression of four miRNAs (miR-30c, miR-30d, miR-30e-3p, miR-370) was significantly different between carcinomas and benign ovarian tissues as well as between carcinoma and borderline tissues. An additional three miRNAs (miR-181d, miR-30a-3p, miR-532-5p) were significantly different between borderline and carcinoma tissues." tissue_expression_ns hsa-mir-30c-1 Ovarian Neoplasms 22925189 "Expression of four miRNAs (miR-30c, miR-30d, miR-30e-3p, miR-370) was significantly different between carcinomas and benign ovarian tissues as well as between carcinoma and borderline tissues. An additional three miRNAs (miR-181d, miR-30a-3p, miR-532-5p) were significantly different between borderline and carcinoma tissues." tissue_expression_ns hsa-mir-30c-2 Ovarian Neoplasms 22925189 "Expression of four miRNAs (miR-30c, miR-30d, miR-30e-3p, miR-370) was significantly different between carcinomas and benign ovarian tissues as well as between carcinoma and borderline tissues. An additional three miRNAs (miR-181d, miR-30a-3p, miR-532-5p) were significantly different between borderline and carcinoma tissues." tissue_expression_ns hsa-mir-30d Ovarian Neoplasms 22925189 "Expression of four miRNAs (miR-30c, miR-30d, miR-30e-3p, miR-370) was significantly different between carcinomas and benign ovarian tissues as well as between carcinoma and borderline tissues. An additional three miRNAs (miR-181d, miR-30a-3p, miR-532-5p) were significantly different between borderline and carcinoma tissues." tissue_expression_ns hsa-mir-30e Ovarian Neoplasms 22925189 "Expression of four miRNAs (miR-30c, miR-30d, miR-30e-3p, miR-370) was significantly different between carcinomas and benign ovarian tissues as well as between carcinoma and borderline tissues. An additional three miRNAs (miR-181d, miR-30a-3p, miR-532-5p) were significantly different between borderline and carcinoma tissues." tissue_expression_ns hsa-mir-370 Ovarian Neoplasms 22925189 "Expression of four miRNAs (miR-30c, miR-30d, miR-30e-3p, miR-370) was significantly different between carcinomas and benign ovarian tissues as well as between carcinoma and borderline tissues. An additional three miRNAs (miR-181d, miR-30a-3p, miR-532-5p) were significantly different between borderline and carcinoma tissues." tissue_expression_ns hsa-mir-532 Ovarian Neoplasms 22925189 "Expression of four miRNAs (miR-30c, miR-30d, miR-30e-3p, miR-370) was significantly different between carcinomas and benign ovarian tissues as well as between carcinoma and borderline tissues. An additional three miRNAs (miR-181d, miR-30a-3p, miR-532-5p) were significantly different between borderline and carcinoma tissues." tissue_expression_ns hsa-mir-126 Coronary Artery Disease 22925274 "MiR-126 was not significantly down-regulated or up-regulated in CAD patients. Interestingly, the level of miR-126 was significantly decreased in patients with CAD and high low-density lipoprotein (LDL) cholesterol level. In contrast, the level of miR-126 was significantly increased when LDL cholesterol was high in patients who had risk factors for CAD but did not have angiographically significant CAD." tissue_expression_ns hsa-mir-182 "Shock, Septic" 22940033 "We confirmed expression of select miRNAs (miR-182, -199a-5p, -203, -211, -222, and -29b) using quantitative reverse transcriptase-polymerase chain reaction." tissue_expression_ns hsa-mir-199a "Shock, Septic" 22940033 "We confirmed expression of select miRNAs (miR-182, -199a-5p, -203, -211, -222, and -29b) using quantitative reverse transcriptase-polymerase chain reaction." tissue_expression_ns hsa-mir-203 "Shock, Septic" 22940033 "We confirmed expression of select miRNAs (miR-182, -199a-5p, -203, -211, -222, and -29b) using quantitative reverse transcriptase-polymerase chain reaction." tissue_expression_ns hsa-mir-211 "Shock, Septic" 22940033 "We confirmed expression of select miRNAs (miR-182, -199a-5p, -203, -211, -222, and -29b) using quantitative reverse transcriptase-polymerase chain reaction." tissue_expression_ns hsa-mir-222 "Shock, Septic" 22940033 "We confirmed expression of select miRNAs (miR-182, -199a-5p, -203, -211, -222, and -29b) using quantitative reverse transcriptase-polymerase chain reaction." tissue_expression_ns hsa-mir-29b "Shock, Septic" 22940033 "We confirmed expression of select miRNAs (miR-182, -199a-5p, -203, -211, -222, and -29b) using quantitative reverse transcriptase-polymerase chain reaction." tissue_expression_ns hsa-mir-145 Bladder Neoplasms 22961325 Assessment of miR-145 levels was able to distinguish bladder cancer patients from non-cancer controls tissue_expression_ns hsa-let-7b Breast Neoplasms 22976804 "By means of RT-qPCR, we further investigated miRNA expression in more IMPC (n?=?22) and IDC-NSTs (n?=?24) FFPE samples and found let-7b, miR-30c, miR-148a, miR-181a, miR-181a*, and miR-181b were significantly differently expressed between the two groups. " tissue_expression_ns hsa-mir-148a Breast Neoplasms 22976804 "By means of RT-qPCR, we further investigated miRNA expression in more IMPC (n?=?22) and IDC-NSTs (n?=?24) FFPE samples and found let-7b, miR-30c, miR-148a, miR-181a, miR-181a*, and miR-181b were significantly differently expressed between the two groups. " tissue_expression_ns hsa-mir-181a Breast Neoplasms 22976804 "By means of RT-qPCR, we further investigated miRNA expression in more IMPC (n?=?22) and IDC-NSTs (n?=?24) FFPE samples and found let-7b, miR-30c, miR-148a, miR-181a, miR-181a*, and miR-181b were significantly differently expressed between the two groups. " tissue_expression_ns hsa-mir-181b Breast Neoplasms 22976804 "By means of RT-qPCR, we further investigated miRNA expression in more IMPC (n?=?22) and IDC-NSTs (n?=?24) FFPE samples and found let-7b, miR-30c, miR-148a, miR-181a, miR-181a*, and miR-181b were significantly differently expressed between the two groups. " tissue_expression_ns hsa-mir-30c Breast Neoplasms 22976804 "By means of RT-qPCR, we further investigated miRNA expression in more IMPC (n?=?22) and IDC-NSTs (n?=?24) FFPE samples and found let-7b, miR-30c, miR-148a, miR-181a, miR-181a*, and miR-181b were significantly differently expressed between the two groups. " tissue_expression_ns hsa-let-7a "Carcinoma, Lung, Non-Small-Cell" 23043708 "The relative expressions of 11 miRNAs in sputum (miR-21, miR-145,miR-155, miR-205, miR-210, miR-92, miR-17-5p, miR-143, miR-182, miR-372, and let-7a) in addition to U6 were retrospectively assessed in four NSCLC-positive and four negative controls." tissue_expression_ns hsa-mir-143 "Carcinoma, Lung, Non-Small-Cell" 23043708 "The relative expressions of 11 miRNAs in sputum (miR-21, miR-145,miR-155, miR-205, miR-210, miR-92, miR-17-5p, miR-143, miR-182, miR-372, and let-7a) in addition to U6 were retrospectively assessed in four NSCLC-positive and four negative controls." tissue_expression_ns hsa-mir-145 "Carcinoma, Lung, Non-Small-Cell" 23043708 "The relative expressions of 11 miRNAs in sputum (miR-21, miR-145,miR-155, miR-205, miR-210, miR-92, miR-17-5p, miR-143, miR-182, miR-372, and let-7a) in addition to U6 were retrospectively assessed in four NSCLC-positive and four negative controls." tissue_expression_ns hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 23043708 "The relative expressions of 11 miRNAs in sputum (miR-21, miR-145,miR-155, miR-205, miR-210, miR-92, miR-17-5p, miR-143, miR-182, miR-372, and let-7a) in addition to U6 were retrospectively assessed in four NSCLC-positive and four negative controls." tissue_expression_ns hsa-mir-17 "Carcinoma, Lung, Non-Small-Cell" 23043708 "The relative expressions of 11 miRNAs in sputum (miR-21, miR-145,miR-155, miR-205, miR-210, miR-92, miR-17-5p, miR-143, miR-182, miR-372, and let-7a) in addition to U6 were retrospectively assessed in four NSCLC-positive and four negative controls." tissue_expression_ns hsa-mir-182 "Carcinoma, Lung, Non-Small-Cell" 23043708 "The relative expressions of 11 miRNAs in sputum (miR-21, miR-145,miR-155, miR-205, miR-210, miR-92, miR-17-5p, miR-143, miR-182, miR-372, and let-7a) in addition to U6 were retrospectively assessed in four NSCLC-positive and four negative controls." tissue_expression_ns hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 23043708 "The relative expressions of 11 miRNAs in sputum (miR-21, miR-145,miR-155, miR-205, miR-210, miR-92, miR-17-5p, miR-143, miR-182, miR-372, and let-7a) in addition to U6 were retrospectively assessed in four NSCLC-positive and four negative controls." tissue_expression_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 23043708 "The relative expressions of 11 miRNAs in sputum (miR-21, miR-145,miR-155, miR-205, miR-210, miR-92, miR-17-5p, miR-143, miR-182, miR-372, and let-7a) in addition to U6 were retrospectively assessed in four NSCLC-positive and four negative controls." tissue_expression_ns hsa-mir-210 "Carcinoma, Lung, Non-Small-Cell" 23043708 "The relative expressions of 11 miRNAs in sputum (miR-21, miR-145,miR-155, miR-205, miR-210, miR-92, miR-17-5p, miR-143, miR-182, miR-372, and let-7a) in addition to U6 were retrospectively assessed in four NSCLC-positive and four negative controls." tissue_expression_ns hsa-mir-372 "Carcinoma, Lung, Non-Small-Cell" 23043708 "The relative expressions of 11 miRNAs in sputum (miR-21, miR-145,miR-155, miR-205, miR-210, miR-92, miR-17-5p, miR-143, miR-182, miR-372, and let-7a) in addition to U6 were retrospectively assessed in four NSCLC-positive and four negative controls." tissue_expression_ns hsa-mir-92 "Carcinoma, Lung, Non-Small-Cell" 23043708 "The relative expressions of 11 miRNAs in sputum (miR-21, miR-145,miR-155, miR-205, miR-210, miR-92, miR-17-5p, miR-143, miR-182, miR-372, and let-7a) in addition to U6 were retrospectively assessed in four NSCLC-positive and four negative controls." tissue_expression_ns hsa-mir-183 "Carcinoma, Thyroid, Medullary" 23072640 "This further validates previously reported miRNA profile analyses and reiterates the potential significance of miR-9*, -183 and -375 in the pathophysiology of MTC." tissue_expression_ns hsa-mir-375 "Carcinoma, Thyroid, Medullary" 23072640 "This further validates previously reported miRNA profile analyses and reiterates the potential significance of miR-9*, -183 and -375 in the pathophysiology of MTC." tissue_expression_ns hsa-mir-9 "Carcinoma, Thyroid, Medullary" 23072640 "This further validates previously reported miRNA profile analyses and reiterates the potential significance of miR-9*, -183 and -375 in the pathophysiology of MTC." tissue_expression_ns hsa-mir-200a "Carcinoma, Renal Cell" 23074016 The entire miR-200 seed family is strongly deregulated in clear cell renal cell cancer compared to the proximal tubular epithelial cells of the kidney tissue_expression_ns hsa-mir-200b "Carcinoma, Renal Cell" 23074016 The entire miR-200 seed family is strongly deregulated in clear cell renal cell cancer compared to the proximal tubular epithelial cells of the kidney tissue_expression_ns hsa-mir-200c "Carcinoma, Renal Cell" 23074016 The entire miR-200 seed family is strongly deregulated in clear cell renal cell cancer compared to the proximal tubular epithelial cells of the kidney tissue_expression_ns hsa-mir-196a "Squamous Cell Carcinoma, Lung" 23074073 "Validation of selected microRNAs by in situ hybridization demonstrated strong expression of hsa-miR-196a in the inner tumor; moderate expression of hsa-miR-224 in the inner tumor and tumor front, and strong expression of hsa-miR-650 in the adjacent lung tissue." tissue_expression_ns hsa-mir-224 "Squamous Cell Carcinoma, Lung" 23074073 "Validation of selected microRNAs by in situ hybridization demonstrated strong expression of hsa-miR-196a in the inner tumor; moderate expression of hsa-miR-224 in the inner tumor and tumor front, and strong expression of hsa-miR-650 in the adjacent lung tissue." tissue_expression_ns hsa-mir-650 "Squamous Cell Carcinoma, Lung" 23074073 "Validation of selected microRNAs by in situ hybridization demonstrated strong expression of hsa-miR-196a in the inner tumor; moderate expression of hsa-miR-224 in the inner tumor and tumor front, and strong expression of hsa-miR-650 in the adjacent lung tissue." tissue_expression_ns hsa-mir-16 Preeclampsia 23083510 "Together, these data suggest that the alteration of miR-16 expression in decidua-derived mesenchymal stem cells may be involved in the development of pre-eclampsia." tissue_expression_ns hsa-mir-143 Esophageal Neoplasms 23092342 "There are several microRNAs that have been consistently reported to be differentially expressed in esophageal squamous cell carcinoma vs. normal squamous tissue, with prognostic associations for miR-21 (invasion, positive nodes, decreased survival), miR-143 (disease recurrence, invasion depth), and miR-375 (inversely correlated with advanced stage, distant metastasis, poor overall survival, and disease-free survival)." tissue_expression_ns hsa-mir-21 Esophageal Neoplasms 23092342 "There are several microRNAs that have been consistently reported to be differentially expressed in esophageal squamous cell carcinoma vs. normal squamous tissue, with prognostic associations for miR-21 (invasion, positive nodes, decreased survival), miR-143 (disease recurrence, invasion depth), and miR-375 (inversely correlated with advanced stage, distant metastasis, poor overall survival, and disease-free survival)." tissue_expression_ns hsa-mir-375 Esophageal Neoplasms 23092342 "There are several microRNAs that have been consistently reported to be differentially expressed in esophageal squamous cell carcinoma vs. normal squamous tissue, with prognostic associations for miR-21 (invasion, positive nodes, decreased survival), miR-143 (disease recurrence, invasion depth), and miR-375 (inversely correlated with advanced stage, distant metastasis, poor overall survival, and disease-free survival)." tissue_expression_ns hsa-mir-210 "Carcinoma, Renal Cell" 23150176 MiR-210 expression in tumor tissue and in vitro effects of its silencing in renal cell carcinoma tissue_expression_ns hsa-mir-155 Breast Neoplasms 23162645 miR-155 and miR-31 are differentially expressed in breast cancer patients and are correlated with the estrogen receptor and progesterone receptor status tissue_expression_ns hsa-mir-31 Breast Neoplasms 23162645 miR-155 and miR-31 are differentially expressed in breast cancer patients and are correlated with the estrogen receptor and progesterone receptor status tissue_expression_ns hsa-mir-146b "Squamous Cell Carcinoma, Esophageal" 23175214 "The expression levels of miR-21 (p = 0.027), miR-181b (p = 0.002) and miR-146b (p = 0.021) in tumor tissue and miR-21 (p = 0.003) in noncancerous tissue were associated with overall survival of patients. " tissue_expression_ns hsa-mir-181b "Squamous Cell Carcinoma, Esophageal" 23175214 "The expression levels of miR-21 (p = 0.027), miR-181b (p = 0.002) and miR-146b (p = 0.021) in tumor tissue and miR-21 (p = 0.003) in noncancerous tissue were associated with overall survival of patients. " tissue_expression_ns hsa-mir-21 "Squamous Cell Carcinoma, Esophageal" 23175214 "The expression levels of miR-21 (p = 0.027), miR-181b (p = 0.002) and miR-146b (p = 0.021) in tumor tissue and miR-21 (p = 0.003) in noncancerous tissue were associated with overall survival of patients. " tissue_expression_ns hsa-mir-182 Prostate Neoplasms 23184537 Expression of MicroRNAs associated with Gleason grading system in prostate cancer: miR-182-5p is a useful marker for high grade prostate cancer tissue_expression_ns hsa-mir-24-1 "Carcinoma, Hepatocellular" 23229173 Human hepatocellular carcinoma cell-specific miRNAs reveal the differential expression of miR-24 and miR-27a in cirrhotic/non-cirrhotic HCC tissue_expression_ns hsa-mir-24-2 "Carcinoma, Hepatocellular" 23229173 Human hepatocellular carcinoma cell-specific miRNAs reveal the differential expression of miR-24 and miR-27a in cirrhotic/non-cirrhotic HCC tissue_expression_ns hsa-mir-27a "Carcinoma, Hepatocellular" 23229173 Human hepatocellular carcinoma cell-specific miRNAs reveal the differential expression of miR-24 and miR-27a in cirrhotic/non-cirrhotic HCC tissue_expression_ns hsa-mir-21 Laryngeal Neoplasms 23259291 Expression of mir-21 and mir-375 in laryngeal squamous cell carcinoma tissue_expression_ns hsa-mir-375 Laryngeal Neoplasms 23259291 Expression of mir-21 and mir-375 in laryngeal squamous cell carcinoma tissue_expression_ns hsa-mir-124 Mesial Temporal Lobe Epilepsy 23315173 "Expression patterns of miR-124, miR-134, miR-132, and miR-21 in an immature rat model and children with mesial temporal lobe epilepsy." tissue_expression_ns hsa-mir-132 Mesial Temporal Lobe Epilepsy 23315173 "Expression patterns of miR-124, miR-134, miR-132, and miR-21 in an immature rat model and children with mesial temporal lobe epilepsy." tissue_expression_ns hsa-mir-134 Mesial Temporal Lobe Epilepsy 23315173 "Expression patterns of miR-124, miR-134, miR-132, and miR-21 in an immature rat model and children with mesial temporal lobe epilepsy." tissue_expression_ns hsa-mir-21 Mesial Temporal Lobe Epilepsy 23315173 "Expression patterns of miR-124, miR-134, miR-132, and miR-21 in an immature rat model and children with mesial temporal lobe epilepsy." tissue_expression_ns hsa-mir-150 Myeloproliferative Neoplasms 23343777 "An aberrant expression of miRNAs 10a and 150 could be demonstrated for essential thrombocythemia and PMF as well as for polycythemia vera and PMF, respectively. The expression of miR-150 could further be shown to correlate with both JAK2 allele burden and peripheral blood counts." tissue_expression_ns hsa-mir-31 Immune System Disease [unspecific] 23352895 "Bantam, miR-276*, miR-10, miR-31 and miR-184 were detected as five most abundant miRNAs in both libraries and 96 miRNAs were identified that were differentially expressed after parasitization." tissue_expression_ns hsa-let-7a Lung Neoplasms 23365639 "Specifically, let-7 and miR-9 are deregulated in both lung cancers and other solid malignancies." tissue_expression_ns hsa-mir-9 Lung Neoplasms 23365639 "Specifically, let-7 and miR-9 are deregulated in both lung cancers and other solid malignancies." tissue_expression_ns hsa-let-7a Melanoma 23377970 "Detailed studies of different groups thereafter identified miRNAs with differential expression in benign melanocytes compared with melanoma cell lines or in benign melanocytic lesions compared with melanomas. Among these were let-7a and b, miR-23a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR214, and miR-221 and 222." tissue_expression_ns hsa-let-7b Melanoma 23377970 "Detailed studies of different groups thereafter identified miRNAs with differential expression in benign melanocytes compared with melanoma cell lines or in benign melanocytic lesions compared with melanomas. Among these were let-7a and b, miR-23a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR214, and miR-221 and 222." tissue_expression_ns hsa-mir-148 Melanoma 23377970 "Detailed studies of different groups thereafter identified miRNAs with differential expression in benign melanocytes compared with melanoma cell lines or in benign melanocytic lesions compared with melanomas. Among these were let-7a and b, miR-23a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR214, and miR-221 and 222." tissue_expression_ns hsa-mir-155 Melanoma 23377970 "Detailed studies of different groups thereafter identified miRNAs with differential expression in benign melanocytes compared with melanoma cell lines or in benign melanocytic lesions compared with melanomas. Among these were let-7a and b, miR-23a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR214, and miR-221 and 222." tissue_expression_ns hsa-mir-182 Melanoma 23377970 "Detailed studies of different groups thereafter identified miRNAs with differential expression in benign melanocytes compared with melanoma cell lines or in benign melanocytic lesions compared with melanomas. Among these were let-7a and b, miR-23a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR214, and miR-221 and 222." tissue_expression_ns hsa-mir-200c Melanoma 23377970 "Detailed studies of different groups thereafter identified miRNAs with differential expression in benign melanocytes compared with melanoma cell lines or in benign melanocytic lesions compared with melanomas. Among these were let-7a and b, miR-23a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR214, and miR-221 and 222." tissue_expression_ns hsa-mir-211 Melanoma 23377970 "Detailed studies of different groups thereafter identified miRNAs with differential expression in benign melanocytes compared with melanoma cell lines or in benign melanocytic lesions compared with melanomas. Among these were let-7a and b, miR-23a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR214, and miR-221 and 222." tissue_expression_ns hsa-mir-214 Melanoma 23377970 "Detailed studies of different groups thereafter identified miRNAs with differential expression in benign melanocytes compared with melanoma cell lines or in benign melanocytic lesions compared with melanomas. Among these were let-7a and b, miR-23a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR214, and miR-221 and 222." tissue_expression_ns hsa-mir-221 Melanoma 23377970 "Detailed studies of different groups thereafter identified miRNAs with differential expression in benign melanocytes compared with melanoma cell lines or in benign melanocytic lesions compared with melanomas. Among these were let-7a and b, miR-23a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR214, and miR-221 and 222." tissue_expression_ns hsa-mir-222 Melanoma 23377970 "Detailed studies of different groups thereafter identified miRNAs with differential expression in benign melanocytes compared with melanoma cell lines or in benign melanocytic lesions compared with melanomas. Among these were let-7a and b, miR-23a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR214, and miR-221 and 222." tissue_expression_ns hsa-mir-23a Melanoma 23377970 "Detailed studies of different groups thereafter identified miRNAs with differential expression in benign melanocytes compared with melanoma cell lines or in benign melanocytic lesions compared with melanomas. Among these were let-7a and b, miR-23a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR214, and miR-221 and 222." tissue_expression_ns hsa-mir-23b Melanoma 23377970 "Detailed studies of different groups thereafter identified miRNAs with differential expression in benign melanocytes compared with melanoma cell lines or in benign melanocytic lesions compared with melanomas. Among these were let-7a and b, miR-23a and b, miR-148, miR-155, miR-182, miR-200c, miR-211, miR214, and miR-221 and 222." tissue_expression_ns hsa-mir-103 "Diabetes Mellitus, Type 2" 23389544 "The deregulation of miRNAs miR-143 (ref. 4), miR-181 (ref. 5), and miR-103 and miR-107 (ref. 6) alters hepatic insulin sensitivity." tissue_expression_ns hsa-mir-107 "Diabetes Mellitus, Type 2" 23389544 "The deregulation of miRNAs miR-143 (ref. 4), miR-181 (ref. 5), and miR-103 and miR-107 (ref. 6) alters hepatic insulin sensitivity." tissue_expression_ns hsa-mir-143 "Diabetes Mellitus, Type 2" 23389544 "The deregulation of miRNAs miR-143 (ref. 4), miR-181 (ref. 5), and miR-103 and miR-107 (ref. 6) alters hepatic insulin sensitivity." tissue_expression_ns hsa-mir-181 "Diabetes Mellitus, Type 2" 23389544 "The deregulation of miRNAs miR-143 (ref. 4), miR-181 (ref. 5), and miR-103 and miR-107 (ref. 6) alters hepatic insulin sensitivity." tissue_expression_ns hsa-mir-181-2 "Carcinoma, Thyroid, Papillary" 23427895 "Fourteen miRNAs were deregulated in FVPTC with a fold change of more than five (up/down), including miRNAs known to be upregulated in PTC (miR-146b-3p, -146-5p, -221, -222 and miR-222-5p) and novel miRNAs (miR-375, -551b, 181-2-3p, 99b-3p)." tissue_expression_ns hsa-mir-375 "Carcinoma, Thyroid, Papillary" 23427895 "Fourteen miRNAs were deregulated in FVPTC with a fold change of more than five (up/down), including miRNAs known to be upregulated in PTC (miR-146b-3p, -146-5p, -221, -222 and miR-222-5p) and novel miRNAs (miR-375, -551b, 181-2-3p, 99b-3p)." tissue_expression_ns hsa-mir-551b "Carcinoma, Thyroid, Papillary" 23427895 "Fourteen miRNAs were deregulated in FVPTC with a fold change of more than five (up/down), including miRNAs known to be upregulated in PTC (miR-146b-3p, -146-5p, -221, -222 and miR-222-5p) and novel miRNAs (miR-375, -551b, 181-2-3p, 99b-3p)." tissue_expression_ns hsa-mir-99b "Carcinoma, Thyroid, Papillary" 23427895 "Fourteen miRNAs were deregulated in FVPTC with a fold change of more than five (up/down), including miRNAs known to be upregulated in PTC (miR-146b-3p, -146-5p, -221, -222 and miR-222-5p) and novel miRNAs (miR-375, -551b, 181-2-3p, 99b-3p)." tissue_expression_ns hsa-mir-146b Gastrointestinal Neoplasms 23456798 "The deregulation of miR-146b-5p, miR-375, miR-148a, miR-31, and miR-451 was associated significantly with gastric adenocarcinomas." tissue_expression_ns hsa-mir-148a Gastrointestinal Neoplasms 23456798 "The deregulation of miR-146b-5p, miR-375, miR-148a, miR-31, and miR-451 was associated significantly with gastric adenocarcinomas." tissue_expression_ns hsa-mir-31 Gastrointestinal Neoplasms 23456798 "The deregulation of miR-146b-5p, miR-375, miR-148a, miR-31, and miR-451 was associated significantly with gastric adenocarcinomas." tissue_expression_ns hsa-mir-375 Gastrointestinal Neoplasms 23456798 "The deregulation of miR-146b-5p, miR-375, miR-148a, miR-31, and miR-451 was associated significantly with gastric adenocarcinomas." tissue_expression_ns hsa-mir-451 Gastrointestinal Neoplasms 23456798 "The deregulation of miR-146b-5p, miR-375, miR-148a, miR-31, and miR-451 was associated significantly with gastric adenocarcinomas." tissue_expression_ns hsa-mir-126 Cholangiocarcinoma 23458262 Concomitant dysregulation of microRNAs miR-151-3p and miR-126 correlates with improved survival in resected cholangiocarcinoma tissue_expression_ns hsa-mir-151 Cholangiocarcinoma 23458262 Concomitant dysregulation of microRNAs miR-151-3p and miR-126 correlates with improved survival in resected cholangiocarcinoma tissue_expression_ns hsa-mir-302b Ovarian Neoplasms 23484053 hsa-miR-302b expression was significantly associated with time to relapse or overall survival in two data sets of platinum-treated ovarian cancer patients. tissue_expression_ns hsa-mir-1303 "Carcinoma, Breast" 23526361 "Among these, a 5-miRNA signature comprising miR-421, miR-486, miR-503, miR-720 and miR-1303 was shown to be predictive for IBC phenotype with an overall accuracy of 89%. " tissue_expression_ns hsa-mir-421 "Carcinoma, Breast" 23526361 "Among these, a 5-miRNA signature comprising miR-421, miR-486, miR-503, miR-720 and miR-1303 was shown to be predictive for IBC phenotype with an overall accuracy of 89%. " tissue_expression_ns hsa-mir-486 "Carcinoma, Breast" 23526361 "Among these, a 5-miRNA signature comprising miR-421, miR-486, miR-503, miR-720 and miR-1303 was shown to be predictive for IBC phenotype with an overall accuracy of 89%. " tissue_expression_ns hsa-mir-503 "Carcinoma, Breast" 23526361 "Among these, a 5-miRNA signature comprising miR-421, miR-486, miR-503, miR-720 and miR-1303 was shown to be predictive for IBC phenotype with an overall accuracy of 89%. " tissue_expression_ns hsa-mir-720 "Carcinoma, Breast" 23526361 "Among these, a 5-miRNA signature comprising miR-421, miR-486, miR-503, miR-720 and miR-1303 was shown to be predictive for IBC phenotype with an overall accuracy of 89%. " tissue_expression_ns hsa-mir-21 Viral Myocarditis 23544605 Myocardial miR-21 expression was negatively related to viral myocarditis severity. tissue_expression_ns hsa-mir-135b Colorectal Carcinoma 23568010 "our results are contradictory to previous studies performed on the CRC patients from Chinese population, providing an evidence against usage of serum miR-17-3p, miR-29a, miR-92a and miR-135b as new biomarkers for early detection of CRC" tissue_expression_ns hsa-mir-17 Colorectal Carcinoma 23568010 "our results are contradictory to previous studies performed on the CRC patients from Chinese population, providing an evidence against usage of serum miR-17-3p, miR-29a, miR-92a and miR-135b as new biomarkers for early detection of CRC" tissue_expression_ns hsa-mir-29a Colorectal Carcinoma 23568010 "our results are contradictory to previous studies performed on the CRC patients from Chinese population, providing an evidence against usage of serum miR-17-3p, miR-29a, miR-92a and miR-135b as new biomarkers for early detection of CRC" tissue_expression_ns hsa-mir-92a Colorectal Carcinoma 23568010 "our results are contradictory to previous studies performed on the CRC patients from Chinese population, providing an evidence against usage of serum miR-17-3p, miR-29a, miR-92a and miR-135b as new biomarkers for early detection of CRC" tissue_expression_ns hsa-mir-221 Ovarian Neoplasms 23569131 Prognostic significance of serum microRNA-221 expression in human epithelial ovarian cancer tissue_expression_ns hsa-mir-192 "Adenocarcinoma, Pancreatic Ductal" 23612862 miRNA expression profiling of human PDACs and adjacent normal pancreatic tissues identified 16 upregulated miRNAs including miR-192 and 8 downregulated miRNAs. tissue_expression_ns hsa-mir-100 Prostate Neoplasms 23621234 "In conclusion, expression changes in miRNAs of miR-146a, miR-100, miR-425, miR-193a-3p and, miR-106b in metformin-treated cells may be important." tissue_expression_ns hsa-mir-106b Prostate Neoplasms 23621234 "In conclusion, expression changes in miRNAs of miR-146a, miR-100, miR-425, miR-193a-3p and, miR-106b in metformin-treated cells may be important." tissue_expression_ns hsa-mir-146a Prostate Neoplasms 23621234 "In conclusion, expression changes in miRNAs of miR-146a, miR-100, miR-425, miR-193a-3p and, miR-106b in metformin-treated cells may be important." tissue_expression_ns hsa-mir-193a Prostate Neoplasms 23621234 "In conclusion, expression changes in miRNAs of miR-146a, miR-100, miR-425, miR-193a-3p and, miR-106b in metformin-treated cells may be important." tissue_expression_ns hsa-mir-425 Prostate Neoplasms 23621234 "In conclusion, expression changes in miRNAs of miR-146a, miR-100, miR-425, miR-193a-3p and, miR-106b in metformin-treated cells may be important." tissue_expression_ns hsa-mir-141 "Carcinoma, Renal Cell" 23635949 "Our recent studies of microRNA (miRNA) expression signatures demonstrated that the epithelial-mesenchymal transition (EMT)-related microRNA-200 family (miR-200s: miR-200a/b/c, miR-141 and miR-429) were significantly downregulated in renal cell carcinoma (RCC) and putative tumor-suppressive miRNAs in RCC." tissue_expression_ns hsa-mir-200a "Carcinoma, Renal Cell" 23635949 "Our recent studies of microRNA (miRNA) expression signatures demonstrated that the epithelial-mesenchymal transition (EMT)-related microRNA-200 family (miR-200s: miR-200a/b/c, miR-141 and miR-429) were significantly downregulated in renal cell carcinoma (RCC) and putative tumor-suppressive miRNAs in RCC." tissue_expression_ns hsa-mir-200b "Carcinoma, Renal Cell" 23635949 "Our recent studies of microRNA (miRNA) expression signatures demonstrated that the epithelial-mesenchymal transition (EMT)-related microRNA-200 family (miR-200s: miR-200a/b/c, miR-141 and miR-429) were significantly downregulated in renal cell carcinoma (RCC) and putative tumor-suppressive miRNAs in RCC." tissue_expression_ns hsa-mir-200c "Carcinoma, Renal Cell" 23635949 "Our recent studies of microRNA (miRNA) expression signatures demonstrated that the epithelial-mesenchymal transition (EMT)-related microRNA-200 family (miR-200s: miR-200a/b/c, miR-141 and miR-429) were significantly downregulated in renal cell carcinoma (RCC) and putative tumor-suppressive miRNAs in RCC." tissue_expression_ns hsa-mir-429 "Carcinoma, Renal Cell" 23635949 "Our recent studies of microRNA (miRNA) expression signatures demonstrated that the epithelial-mesenchymal transition (EMT)-related microRNA-200 family (miR-200s: miR-200a/b/c, miR-141 and miR-429) were significantly downregulated in renal cell carcinoma (RCC) and putative tumor-suppressive miRNAs in RCC." tissue_expression_ns hsa-mir-1 "Carcinoma, Skin" 23646287 "Differential expression of miR-1, a putative tumor suppressing microRNA, in cancer resistant and cancer susceptible mice." tissue_expression_ns hsa-mir-106b Colorectal Carcinoma 23690963 "Nine of the twelve miRNAs (miR-18a, -20a, -21, -29a, -92a, -106b, -133a, -143, -145) were found to be differentially expressed in CRC patients and controls in the validation samples." tissue_expression_ns hsa-mir-133a Colorectal Carcinoma 23690963 "Nine of the twelve miRNAs (miR-18a, -20a, -21, -29a, -92a, -106b, -133a, -143, -145) were found to be differentially expressed in CRC patients and controls in the validation samples." tissue_expression_ns hsa-mir-143 Colorectal Carcinoma 23690963 "Nine of the twelve miRNAs (miR-18a, -20a, -21, -29a, -92a, -106b, -133a, -143, -145) were found to be differentially expressed in CRC patients and controls in the validation samples." tissue_expression_ns hsa-mir-145 Colorectal Carcinoma 23690963 "Nine of the twelve miRNAs (miR-18a, -20a, -21, -29a, -92a, -106b, -133a, -143, -145) were found to be differentially expressed in CRC patients and controls in the validation samples." tissue_expression_ns hsa-mir-18a Colorectal Carcinoma 23690963 "Nine of the twelve miRNAs (miR-18a, -20a, -21, -29a, -92a, -106b, -133a, -143, -145) were found to be differentially expressed in CRC patients and controls in the validation samples." tissue_expression_ns hsa-mir-20a Colorectal Carcinoma 23690963 "Nine of the twelve miRNAs (miR-18a, -20a, -21, -29a, -92a, -106b, -133a, -143, -145) were found to be differentially expressed in CRC patients and controls in the validation samples." tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 23690963 "Nine of the twelve miRNAs (miR-18a, -20a, -21, -29a, -92a, -106b, -133a, -143, -145) were found to be differentially expressed in CRC patients and controls in the validation samples." tissue_expression_ns hsa-mir-29a Colorectal Carcinoma 23690963 "Nine of the twelve miRNAs (miR-18a, -20a, -21, -29a, -92a, -106b, -133a, -143, -145) were found to be differentially expressed in CRC patients and controls in the validation samples." tissue_expression_ns hsa-mir-92a Colorectal Carcinoma 23690963 "Nine of the twelve miRNAs (miR-18a, -20a, -21, -29a, -92a, -106b, -133a, -143, -145) were found to be differentially expressed in CRC patients and controls in the validation samples." tissue_expression_ns hsa-mir-147b Neuroblastoma 23724168 "Numerous miRNAs were detected by microarrays to be regulated by the combined lithium and valproic acid treatment, and the following candidates were confirmed using real-time PCR: miR-34a, miR-147b, miR-182,miR-222, miR-495, and miR-690. " tissue_expression_ns hsa-mir-182 Neuroblastoma 23724168 "Numerous miRNAs were detected by microarrays to be regulated by the combined lithium and valproic acid treatment, and the following candidates were confirmed using real-time PCR: miR-34a, miR-147b, miR-182,miR-222, miR-495, and miR-690. " tissue_expression_ns hsa-mir-222 Neuroblastoma 23724168 "Numerous miRNAs were detected by microarrays to be regulated by the combined lithium and valproic acid treatment, and the following candidates were confirmed using real-time PCR: miR-34a, miR-147b, miR-182,miR-222, miR-495, and miR-690. " tissue_expression_ns hsa-mir-34a Neuroblastoma 23724168 "Numerous miRNAs were detected by microarrays to be regulated by the combined lithium and valproic acid treatment, and the following candidates were confirmed using real-time PCR: miR-34a, miR-147b, miR-182,miR-222, miR-495, and miR-690. " tissue_expression_ns hsa-mir-496 Neuroblastoma 23724168 "Numerous miRNAs were detected by microarrays to be regulated by the combined lithium and valproic acid treatment, and the following candidates were confirmed using real-time PCR: miR-34a, miR-147b, miR-182,miR-222, miR-495, and miR-690. " tissue_expression_ns hsa-mir-690 Neuroblastoma 23724168 "Numerous miRNAs were detected by microarrays to be regulated by the combined lithium and valproic acid treatment, and the following candidates were confirmed using real-time PCR: miR-34a, miR-147b, miR-182,miR-222, miR-495, and miR-690. " tissue_expression_ns hsa-mir-146a Urinary Bladder Cancer 23749909 altered expression tissue_expression_ns hsa-mir-155 Urinary Bladder Cancer 23749909 altered expression tissue_expression_ns hsa-mir-196a-1 Urinary Bladder Cancer 23749909 altered expression tissue_expression_ns hsa-mir-196a-2 Urinary Bladder Cancer 23749909 altered expression tissue_expression_ns hsa-mir-203 Urinary Bladder Cancer 23749909 altered expression tissue_expression_ns hsa-mir-21 Urinary Bladder Cancer 23749909 altered expression tissue_expression_ns hsa-mir-221 Urinary Bladder Cancer 23749909 altered expression tissue_expression_ns hsa-mir-27a Urinary Bladder Cancer 23749909 altered expression tissue_expression_ns hsa-mir-34a Urinary Bladder Cancer 23749909 altered expression tissue_expression_ns hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 23759980 Identification of microRNAs differentially expressed between lung squamous cell carcinoma and lung adenocarcinoma. tissue_expression_ns hsa-mir-182 Neoplasms [unspecific] 23791657 Meta-analysis of microRNA-183 family expression in human cancer studies comparing cancer tissues with noncancerous tissues. tissue_expression_ns hsa-mir-183 Neoplasms [unspecific] 23791657 Meta-analysis of microRNA-183 family expression in human cancer studies comparing cancer tissues with noncancerous tissues. tissue_expression_ns hsa-mir-96 Neoplasms [unspecific] 23791657 Meta-analysis of microRNA-183 family expression in human cancer studies comparing cancer tissues with noncancerous tissues. tissue_expression_ns hsa-mir-1 Breast Neoplasms 23797906 "The clinical use of miRNA signatures as a noninvasive diagnostic strategy is promising, but should be further validated for different subtypes of breast cancers." tissue_expression_ns hsa-mir-133a Breast Neoplasms 23797906 "The clinical use of miRNA signatures as a noninvasive diagnostic strategy is promising, but should be further validated for different subtypes of breast cancers." tissue_expression_ns hsa-mir-133b Breast Neoplasms 23797906 "The clinical use of miRNA signatures as a noninvasive diagnostic strategy is promising, but should be further validated for different subtypes of breast cancers." tissue_expression_ns hsa-mir-92a Breast Neoplasms 23797906 "The clinical use of miRNA signatures as a noninvasive diagnostic strategy is promising, but should be further validated for different subtypes of breast cancers." tissue_expression_ns hsa-let-7c "Carcinoma, Renal Cell" 23799849 "MicroRNAs are able to accurately classify RCC samples. Deregulated miRNAs might contribute to the high chemotherapy resistance of RCC. Furthermore, our results indicate that pRCC type 2 tumours could be dependent on oncogenic MYC signalling." tissue_expression_ns hsa-mir-145 "Carcinoma, Renal Cell" 23799849 "MicroRNAs are able to accurately classify RCC samples. Deregulated miRNAs might contribute to the high chemotherapy resistance of RCC. Furthermore, our results indicate that pRCC type 2 tumours could be dependent on oncogenic MYC signalling." tissue_expression_ns hsa-mir-200c "Carcinoma, Renal Cell" 23799849 "MicroRNAs are able to accurately classify RCC samples. Deregulated miRNAs might contribute to the high chemotherapy resistance of RCC. Furthermore, our results indicate that pRCC type 2 tumours could be dependent on oncogenic MYC signalling." tissue_expression_ns hsa-mir-210 "Carcinoma, Renal Cell" 23799849 "MicroRNAs are able to accurately classify RCC samples. Deregulated miRNAs might contribute to the high chemotherapy resistance of RCC. Furthermore, our results indicate that pRCC type 2 tumours could be dependent on oncogenic MYC signalling." tissue_expression_ns hsa-mir-502 "Carcinoma, Renal Cell" 23799849 "MicroRNAs are able to accurately classify RCC samples. Deregulated miRNAs might contribute to the high chemotherapy resistance of RCC. Furthermore, our results indicate that pRCC type 2 tumours could be dependent on oncogenic MYC signalling." tissue_expression_ns hsa-mir-135b "Lymphoma, Large B-Cell" 23801630 MicroRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma. tissue_expression_ns hsa-mir-146a "Lymphoma, Large B-Cell" 23801630 MicroRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma. tissue_expression_ns hsa-mir-155 "Lymphoma, Large B-Cell" 23801630 MicroRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma. tissue_expression_ns hsa-mir-512 "Lymphoma, Large B-Cell" 23801630 MicroRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma. tissue_expression_ns hsa-mir-708 "Lymphoma, Large B-Cell" 23801630 MicroRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma. tissue_expression_ns hsa-mir-886 "Lymphoma, Large B-Cell" 23801630 MicroRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma. tissue_expression_ns hsa-mir-219 Obesity 23817051 "the miRNA profile is altered in amnion during obesity and hypothesize that this could affect pathways important for placental growth and function, thereby contributing to an increase in the newborn's risk of future metabolic diseases." tissue_expression_ns hsa-mir-422b Obesity 23817051 "the miRNA profile is altered in amnion during obesity and hypothesize that this could affect pathways important for placental growth and function, thereby contributing to an increase in the newborn's risk of future metabolic diseases." tissue_expression_ns hsa-mir-523 Obesity 23817051 "the miRNA profile is altered in amnion during obesity and hypothesize that this could affect pathways important for placental growth and function, thereby contributing to an increase in the newborn's risk of future metabolic diseases." tissue_expression_ns hsa-mir-575 Obesity 23817051 "the miRNA profile is altered in amnion during obesity and hypothesize that this could affect pathways important for placental growth and function, thereby contributing to an increase in the newborn's risk of future metabolic diseases." tissue_expression_ns hsa-mir-579 Obesity 23817051 "the miRNA profile is altered in amnion during obesity and hypothesize that this could affect pathways important for placental growth and function, thereby contributing to an increase in the newborn's risk of future metabolic diseases." tissue_expression_ns hsa-mir-618 Obesity 23817051 "the miRNA profile is altered in amnion during obesity and hypothesize that this could affect pathways important for placental growth and function, thereby contributing to an increase in the newborn's risk of future metabolic diseases." tissue_expression_ns hsa-mir-659 Obesity 23817051 "the miRNA profile is altered in amnion during obesity and hypothesize that this could affect pathways important for placental growth and function, thereby contributing to an increase in the newborn's risk of future metabolic diseases." tissue_expression_ns hsa-mir-378 Liver Diseases [unspecific] 23818290 Dietary fisetin protects against hepatosteatosis in association with modulation of lipid metabolism genes and miR-378 in mice tissue_expression_ns hsa-mir-149 Chordoma 23826111 "This study provides an integrated dataset of the miRNA and mRNA profiles in chordomas, and the results demonstrate that not only the MAPK pathway and its related miRNAs but also the Notch pathway may be involved in chordoma development. The occurrence of chordoma may be associated with dysfunctional calcification or ossification of the notochord." tissue_expression_ns hsa-mir-1908 Chordoma 23826111 "This study provides an integrated dataset of the miRNA and mRNA profiles in chordomas, and the results demonstrate that not only the MAPK pathway and its related miRNAs but also the Notch pathway may be involved in chordoma development. The occurrence of chordoma may be associated with dysfunctional calcification or ossification of the notochord." tissue_expression_ns hsa-mir-2861 Chordoma 23826111 "This study provides an integrated dataset of the miRNA and mRNA profiles in chordomas, and the results demonstrate that not only the MAPK pathway and its related miRNAs but also the Notch pathway may be involved in chordoma development. The occurrence of chordoma may be associated with dysfunctional calcification or ossification of the notochord." tissue_expression_ns hsa-mir-3185 Chordoma 23826111 "This study provides an integrated dataset of the miRNA and mRNA profiles in chordomas, and the results demonstrate that not only the MAPK pathway and its related miRNAs but also the Notch pathway may be involved in chordoma development. The occurrence of chordoma may be associated with dysfunctional calcification or ossification of the notochord." tissue_expression_ns hsa-mir-663a Chordoma 23826111 "This study provides an integrated dataset of the miRNA and mRNA profiles in chordomas, and the results demonstrate that not only the MAPK pathway and its related miRNAs but also the Notch pathway may be involved in chordoma development. The occurrence of chordoma may be associated with dysfunctional calcification or ossification of the notochord." tissue_expression_ns hsa-mir-1264 Laryngeal Neoplasms 23826416 Gene and microRNA expression reveals sensitivity to paclitaxel in laryngeal cancer cell line. tissue_expression_ns hsa-mir-1265 Laryngeal Neoplasms 23826416 Gene and microRNA expression reveals sensitivity to paclitaxel in laryngeal cancer cell line. tissue_expression_ns hsa-mir-1277 Laryngeal Neoplasms 23826416 Gene and microRNA expression reveals sensitivity to paclitaxel in laryngeal cancer cell line. tissue_expression_ns hsa-mir-1291 Laryngeal Neoplasms 23826416 Gene and microRNA expression reveals sensitivity to paclitaxel in laryngeal cancer cell line. tissue_expression_ns hsa-mir-130a Laryngeal Neoplasms 23826416 Gene and microRNA expression reveals sensitivity to paclitaxel in laryngeal cancer cell line. tissue_expression_ns hsa-mir-195 Laryngeal Neoplasms 23826416 Gene and microRNA expression reveals sensitivity to paclitaxel in laryngeal cancer cell line. tissue_expression_ns hsa-mir-214 Laryngeal Neoplasms 23826416 Gene and microRNA expression reveals sensitivity to paclitaxel in laryngeal cancer cell line. tissue_expression_ns hsa-mir-27b Laryngeal Neoplasms 23826416 Gene and microRNA expression reveals sensitivity to paclitaxel in laryngeal cancer cell line. tissue_expression_ns hsa-mir-191 Preeclampsia 23830491 Several miRNAs are found to be dysregulated in placentas of PE patients and they seem to be closely associated with the early pathogenesis of PE. Further study is necessary to develop tools for early detection and management. tissue_expression_ns hsa-mir-197 Preeclampsia 23830491 Several miRNAs are found to be dysregulated in placentas of PE patients and they seem to be closely associated with the early pathogenesis of PE. Further study is necessary to develop tools for early detection and management. tissue_expression_ns hsa-mir-198 Preeclampsia 23830491 Several miRNAs are found to be dysregulated in placentas of PE patients and they seem to be closely associated with the early pathogenesis of PE. Further study is necessary to develop tools for early detection and management. tissue_expression_ns hsa-mir-202 Preeclampsia 23830491 Several miRNAs are found to be dysregulated in placentas of PE patients and they seem to be closely associated with the early pathogenesis of PE. Further study is necessary to develop tools for early detection and management. tissue_expression_ns hsa-mir-204 Preeclampsia 23830491 Several miRNAs are found to be dysregulated in placentas of PE patients and they seem to be closely associated with the early pathogenesis of PE. Further study is necessary to develop tools for early detection and management. tissue_expression_ns hsa-mir-25 Preeclampsia 23830491 Several miRNAs are found to be dysregulated in placentas of PE patients and they seem to be closely associated with the early pathogenesis of PE. Further study is necessary to develop tools for early detection and management. tissue_expression_ns hsa-mir-26a Preeclampsia 23830491 Several miRNAs are found to be dysregulated in placentas of PE patients and they seem to be closely associated with the early pathogenesis of PE. Further study is necessary to develop tools for early detection and management. tissue_expression_ns hsa-mir-26b Preeclampsia 23830491 Several miRNAs are found to be dysregulated in placentas of PE patients and they seem to be closely associated with the early pathogenesis of PE. Further study is necessary to develop tools for early detection and management. tissue_expression_ns hsa-mir-296 Preeclampsia 23830491 Several miRNAs are found to be dysregulated in placentas of PE patients and they seem to be closely associated with the early pathogenesis of PE. Further study is necessary to develop tools for early detection and management. tissue_expression_ns hsa-mir-342 Preeclampsia 23830491 Several miRNAs are found to be dysregulated in placentas of PE patients and they seem to be closely associated with the early pathogenesis of PE. Further study is necessary to develop tools for early detection and management. tissue_expression_ns hsa-mir-92b Preeclampsia 23830491 Several miRNAs are found to be dysregulated in placentas of PE patients and they seem to be closely associated with the early pathogenesis of PE. Further study is necessary to develop tools for early detection and management. tissue_expression_ns hsa-mir-95 Preeclampsia 23830491 Several miRNAs are found to be dysregulated in placentas of PE patients and they seem to be closely associated with the early pathogenesis of PE. Further study is necessary to develop tools for early detection and management. tissue_expression_ns hsa-mir-483 "Carcinoma, Ovarian, Serous" 23836287 MiRNA expression signature for potentially predicting the prognosis of ovarian serous carcinoma. tissue_expression_ns hsa-mir-508 "Carcinoma, Ovarian, Serous" 23836287 MiRNA expression signature for potentially predicting the prognosis of ovarian serous carcinoma. tissue_expression_ns hsa-mir-509 "Carcinoma, Ovarian, Serous" 23836287 MiRNA expression signature for potentially predicting the prognosis of ovarian serous carcinoma. tissue_expression_ns hsa-mir-510 "Carcinoma, Ovarian, Serous" 23836287 MiRNA expression signature for potentially predicting the prognosis of ovarian serous carcinoma. tissue_expression_ns hsa-mir-206 Vascular Hypertrophy 23842077 miR-206 was depressed in the hypertrophied RV of Hx rats but was increased in growth-retarded SM. tissue_expression_ns hsa-mir-205 Wounds and Injuries [unspecific] 23861701 "we predicted that topical treatment of shikonin in vivo affects epithelial-mesenchymal transition (EMT) and the expression of related microRNAs, including 200a, 200b, 200c, 141, 205, and 429 microRNAs, in mouse skin tissues." tissue_expression_ns hsa-mir-29b "Carcinoma, Hepatocellular" 23863670 The combined detection of miRNA-29b and AFP aids the diagnosis of PHC and the prediction of its prognosis. tissue_expression_ns hsa-mir-155 Lymphoma 23871213 The expression ratio of miR-17-5p and miR-155 correlates with grading in canine splenic lymphoma. tissue_expression_ns hsa-mir-1246 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-1308 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-141 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-143 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-18a Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-1972 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-1973 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-200a Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-200b Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-210 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-211 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-29b Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-31 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-3172 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-3175 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-375 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-451 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-486 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-663b Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-665 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-675 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-mir-934 Pterygium 23872359 miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium. tissue_expression_ns hsa-let-7e "Colitis, Ulcerative" 23885139 "The present study provides the first evidence that miR-20b, miR-98, miR-125b-1*, and let-7e* are deregulated in patients with UC." tissue_expression_ns hsa-let-7d Asthma 23885321 "Differential expression of miR-1248, miR-26a, Let-7a, and Let-7d were observed in asthmatic patients compared to controls." tissue_expression_ns hsa-mir-15b Gastric Neoplasms 23907579 The modulation of miR-15b and miR-16 mediated the apoptosis effects of DHA in gastric cancer cells. tissue_expression_ns hsa-mir-524 Glioblastoma 23924460 The miRNA gene expression profiles correlate with several selected MRI features of patients with GBM. Further analysis of key imaging features of MRI with correlation with miRNA gene expression patterns may help to guide treatment decisions based on these unique correlative profiles of GBM. tissue_expression_ns hsa-mir-612 Glioblastoma 23924460 The miRNA gene expression profiles correlate with several selected MRI features of patients with GBM. Further analysis of key imaging features of MRI with correlation with miRNA gene expression patterns may help to guide treatment decisions based on these unique correlative profiles of GBM. tissue_expression_ns hsa-mir-210 Ischemia 23931770 "The physiopathological significance of miR-210 is context dependent. In the ischemic skeletal muscle it seems to be cytoprotective, regulating oxidative metabolism and oxidative stress." tissue_expression_ns hsa-let-7g Colorectal Carcinoma 23932154 "Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g." tissue_expression_ns hsa-mir-132 Colorectal Carcinoma 23932154 "Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g." tissue_expression_ns hsa-mir-224 Colorectal Carcinoma 23932154 "Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g." tissue_expression_ns hsa-mir-320a Colorectal Carcinoma 23932154 "Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g." tissue_expression_ns hsa-mir-1280 Neoplasms [unspecific] 23936320 Characterization of microRNA expression profiles and the discovery of novel microRNAs involved in cancer during human embryonic development. tissue_expression_ns hsa-mir-638 Neoplasms [unspecific] 23936320 Characterization of microRNA expression profiles and the discovery of novel microRNAs involved in cancer during human embryonic development. tissue_expression_ns hsa-mir-720 Neoplasms [unspecific] 23936320 Characterization of microRNA expression profiles and the discovery of novel microRNAs involved in cancer during human embryonic development. tissue_expression_ns hsa-mir-106b Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-125b Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-130a Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-130b Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-139 Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-141 Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-145 Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-199a Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-200a Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-205 Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-20a Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-214 Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-222 Bladder Neoplasms 23945108 miRNA profiling identifies candidate mirnas for bladder cancer diagnosis and clinical outcome. tissue_expression_ns hsa-mir-650 "Adenocarcinoma, Lung" 23991130 miR-650 is a novel prognostic marker in LAD and its expression is a potential indicator of chemosensitivity to docetaxel-based chemotherapy regimen. tissue_expression_ns hsa-mir-181b Oral Leukoplakia 24020903 some cytological and histopathological parameters used to grade dysplasia are associated with altered miRNA expression. tissue_expression_ns hsa-mir-21 Oral Leukoplakia 24020903 some cytological and histopathological parameters used to grade dysplasia are associated with altered miRNA expression. tissue_expression_ns hsa-mir-345 Oral Leukoplakia 24020903 some cytological and histopathological parameters used to grade dysplasia are associated with altered miRNA expression. tissue_expression_ns hsa-mir-203 Melanoma 24023765 we found extensive sequence variations (isomiRs) and other non-coding small RNAs revealing a complex melanoma transcriptome. Deep-sequencing small RNAs directly from clinically defined specimens provides a robust strategy to improve melanoma diagnostics. tissue_expression_ns hsa-mir-204 Melanoma 24023765 we found extensive sequence variations (isomiRs) and other non-coding small RNAs revealing a complex melanoma transcriptome. Deep-sequencing small RNAs directly from clinically defined specimens provides a robust strategy to improve melanoma diagnostics. tissue_expression_ns hsa-mir-205 Melanoma 24023765 we found extensive sequence variations (isomiRs) and other non-coding small RNAs revealing a complex melanoma transcriptome. Deep-sequencing small RNAs directly from clinically defined specimens provides a robust strategy to improve melanoma diagnostics. tissue_expression_ns hsa-mir-211 Melanoma 24023765 we found extensive sequence variations (isomiRs) and other non-coding small RNAs revealing a complex melanoma transcriptome. Deep-sequencing small RNAs directly from clinically defined specimens provides a robust strategy to improve melanoma diagnostics. tissue_expression_ns hsa-mir-23b Melanoma 24023765 we found extensive sequence variations (isomiRs) and other non-coding small RNAs revealing a complex melanoma transcriptome. Deep-sequencing small RNAs directly from clinically defined specimens provides a robust strategy to improve melanoma diagnostics. tissue_expression_ns hsa-mir-26a Melanoma 24023765 we found extensive sequence variations (isomiRs) and other non-coding small RNAs revealing a complex melanoma transcriptome. Deep-sequencing small RNAs directly from clinically defined specimens provides a robust strategy to improve melanoma diagnostics. tissue_expression_ns hsa-mir-26b Melanoma 24023765 we found extensive sequence variations (isomiRs) and other non-coding small RNAs revealing a complex melanoma transcriptome. Deep-sequencing small RNAs directly from clinically defined specimens provides a robust strategy to improve melanoma diagnostics. tissue_expression_ns hsa-mir-21 Gastric Neoplasms 24023850 miR-21 has potential diagnostic value with a moderate sensitivity and specificity for GC. More prospective studies on the diagnostic value of miR-21 for GC are needed in the future. tissue_expression_ns hsa-mir-106b "Carcinoma, Gastric" 24040025 Candidate microRNA biomarkers in human gastric cancer: a systematic review and validation study. tissue_expression_ns hsa-mir-17 "Carcinoma, Gastric" 24040025 Candidate microRNA biomarkers in human gastric cancer: a systematic review and validation study. tissue_expression_ns hsa-mir-18a "Carcinoma, Gastric" 24040025 Candidate microRNA biomarkers in human gastric cancer: a systematic review and validation study. tissue_expression_ns hsa-mir-20a "Carcinoma, Gastric" 24040025 Candidate microRNA biomarkers in human gastric cancer: a systematic review and validation study. tissue_expression_ns hsa-mir-21 "Carcinoma, Gastric" 24040025 Candidate microRNA biomarkers in human gastric cancer: a systematic review and validation study. tissue_expression_ns hsa-mir-378 "Carcinoma, Gastric" 24040025 Candidate microRNA biomarkers in human gastric cancer: a systematic review and validation study. tissue_expression_ns hsa-mir-638 "Carcinoma, Gastric" 24040025 Candidate microRNA biomarkers in human gastric cancer: a systematic review and validation study. tissue_expression_ns hsa-mir-196a Pancreatic Neoplasms 24048456 "Our results provide experimental evidence to support aberrant expression of miR-196a is associated with abnormal apoptosis, invasion, and proliferation of pancreatic cancer cells." tissue_expression_ns hsa-mir-146a Inflammatory Bowel Diseases 24051693 "In summary,we demonstrate that miR-31, miR-206, miR-424, and miR-146a are novel specific biomarkers of inflammatory bowel disease." tissue_expression_ns hsa-mir-206 Inflammatory Bowel Diseases 24051693 "In summary,we demonstrate that miR-31, miR-206, miR-424, and miR-146a are novel specific biomarkers of inflammatory bowel disease." tissue_expression_ns hsa-mir-31 Inflammatory Bowel Diseases 24051693 "In summary,we demonstrate that miR-31, miR-206, miR-424, and miR-146a are novel specific biomarkers of inflammatory bowel disease." tissue_expression_ns hsa-mir-424 Inflammatory Bowel Diseases 24051693 "In summary,we demonstrate that miR-31, miR-206, miR-424, and miR-146a are novel specific biomarkers of inflammatory bowel disease." tissue_expression_ns hsa-mir-650 Glioma 24062138 MicroRNA-650 expression in glioma is associated with prognosis of patients. tissue_expression_ns hsa-mir-21 Atrial Fibrillation 24069193 "The expression of miRNA-21 in human atrial tissue was found to be related to atrial fibrosis and might affect AF occurrence, indicating its usefulness as a biomarker for cardiac surgery management." tissue_expression_ns hsa-let-7c Down Syndrome 24071828 Differentially expressed microRNAs may be involved in hemopoietic abnormalities and the immune defects of DS fetuses and newborns. tissue_expression_ns hsa-mir-125b-2 Down Syndrome 24071828 Differentially expressed microRNAs may be involved in hemopoietic abnormalities and the immune defects of DS fetuses and newborns. tissue_expression_ns hsa-mir-155 Down Syndrome 24071828 Differentially expressed microRNAs may be involved in hemopoietic abnormalities and the immune defects of DS fetuses and newborns. tissue_expression_ns hsa-mir-802 Down Syndrome 24071828 Differentially expressed microRNAs may be involved in hemopoietic abnormalities and the immune defects of DS fetuses and newborns. tissue_expression_ns hsa-mir-99a Down Syndrome 24071828 Differentially expressed microRNAs may be involved in hemopoietic abnormalities and the immune defects of DS fetuses and newborns. tissue_expression_ns hsa-mir-106 Colorectal Carcinoma 24078989 MiRNAs might soon represent novel prognostic and diagnostic tools in patients at high risk of CRC or being diagnosed with CRC. tissue_expression_ns hsa-mir-126 Colorectal Carcinoma 24078989 MiRNAs might soon represent novel prognostic and diagnostic tools in patients at high risk of CRC or being diagnosed with CRC. tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 24078989 MiRNAs might soon represent novel prognostic and diagnostic tools in patients at high risk of CRC or being diagnosed with CRC. tissue_expression_ns hsa-mir-26b Colorectal Carcinoma 24078989 MiRNAs might soon represent novel prognostic and diagnostic tools in patients at high risk of CRC or being diagnosed with CRC. tissue_expression_ns hsa-mir-328 Colorectal Carcinoma 24078989 MiRNAs might soon represent novel prognostic and diagnostic tools in patients at high risk of CRC or being diagnosed with CRC. tissue_expression_ns hsa-mir-345 Colorectal Carcinoma 24078989 MiRNAs might soon represent novel prognostic and diagnostic tools in patients at high risk of CRC or being diagnosed with CRC. tissue_expression_ns hsa-mir-92a Colorectal Carcinoma 24078989 MiRNAs might soon represent novel prognostic and diagnostic tools in patients at high risk of CRC or being diagnosed with CRC. tissue_expression_ns hsa-mir-302b "Carcinoma, Hepatocellular" 24083596 miR-302b suppresses HCC growth may due to targeting the EGFR/AKT2/CCND1 pathway. tissue_expression_ns hsa-mir-10a "Cardiomyopathy, Hypertrophic" 24083979 In silico identification of mRNA targets of differentially expressed miRNAs showed a large proportion of genes involved in cardiac hypertrophy and cardiac beta-adrenergic receptor signaling and we showed reduced phosphorylation of cardiac troponin I in the HCM myocardium when compared with donor. HCM patients with MYBPC3 mutations have a specific miRNA expression profile. Downstream mRNA targets reveal possible involvement in cardiac signaling pathways. tissue_expression_ns hsa-mir-10b "Cardiomyopathy, Hypertrophic" 24083979 In silico identification of mRNA targets of differentially expressed miRNAs showed a large proportion of genes involved in cardiac hypertrophy and cardiac beta-adrenergic receptor signaling and we showed reduced phosphorylation of cardiac troponin I in the HCM myocardium when compared with donor. HCM patients with MYBPC3 mutations have a specific miRNA expression profile. Downstream mRNA targets reveal possible involvement in cardiac signaling pathways. tissue_expression_ns hsa-mir-181a-2 "Cardiomyopathy, Hypertrophic" 24083979 In silico identification of mRNA targets of differentially expressed miRNAs showed a large proportion of genes involved in cardiac hypertrophy and cardiac beta-adrenergic receptor signaling and we showed reduced phosphorylation of cardiac troponin I in the HCM myocardium when compared with donor. HCM patients with MYBPC3 mutations have a specific miRNA expression profile. Downstream mRNA targets reveal possible involvement in cardiac signaling pathways. tissue_expression_ns hsa-mir-184 "Cardiomyopathy, Hypertrophic" 24083979 In silico identification of mRNA targets of differentially expressed miRNAs showed a large proportion of genes involved in cardiac hypertrophy and cardiac beta-adrenergic receptor signaling and we showed reduced phosphorylation of cardiac troponin I in the HCM myocardium when compared with donor. HCM patients with MYBPC3 mutations have a specific miRNA expression profile. Downstream mRNA targets reveal possible involvement in cardiac signaling pathways. tissue_expression_ns hsa-mir-204 "Cardiomyopathy, Hypertrophic" 24083979 In silico identification of mRNA targets of differentially expressed miRNAs showed a large proportion of genes involved in cardiac hypertrophy and cardiac beta-adrenergic receptor signaling and we showed reduced phosphorylation of cardiac troponin I in the HCM myocardium when compared with donor. HCM patients with MYBPC3 mutations have a specific miRNA expression profile. Downstream mRNA targets reveal possible involvement in cardiac signaling pathways. tissue_expression_ns hsa-mir-222 "Cardiomyopathy, Hypertrophic" 24083979 In silico identification of mRNA targets of differentially expressed miRNAs showed a large proportion of genes involved in cardiac hypertrophy and cardiac beta-adrenergic receptor signaling and we showed reduced phosphorylation of cardiac troponin I in the HCM myocardium when compared with donor. HCM patients with MYBPC3 mutations have a specific miRNA expression profile. Downstream mRNA targets reveal possible involvement in cardiac signaling pathways. tissue_expression_ns hsa-mir-34b "Cardiomyopathy, Hypertrophic" 24083979 In silico identification of mRNA targets of differentially expressed miRNAs showed a large proportion of genes involved in cardiac hypertrophy and cardiac beta-adrenergic receptor signaling and we showed reduced phosphorylation of cardiac troponin I in the HCM myocardium when compared with donor. HCM patients with MYBPC3 mutations have a specific miRNA expression profile. Downstream mRNA targets reveal possible involvement in cardiac signaling pathways. tissue_expression_ns hsa-mir-371 "Cardiomyopathy, Hypertrophic" 24083979 In silico identification of mRNA targets of differentially expressed miRNAs showed a large proportion of genes involved in cardiac hypertrophy and cardiac beta-adrenergic receptor signaling and we showed reduced phosphorylation of cardiac troponin I in the HCM myocardium when compared with donor. HCM patients with MYBPC3 mutations have a specific miRNA expression profile. Downstream mRNA targets reveal possible involvement in cardiac signaling pathways. tissue_expression_ns hsa-mir-383 "Cardiomyopathy, Hypertrophic" 24083979 In silico identification of mRNA targets of differentially expressed miRNAs showed a large proportion of genes involved in cardiac hypertrophy and cardiac beta-adrenergic receptor signaling and we showed reduced phosphorylation of cardiac troponin I in the HCM myocardium when compared with donor. HCM patients with MYBPC3 mutations have a specific miRNA expression profile. Downstream mRNA targets reveal possible involvement in cardiac signaling pathways. tissue_expression_ns hsa-mir-497 "Cardiomyopathy, Hypertrophic" 24083979 In silico identification of mRNA targets of differentially expressed miRNAs showed a large proportion of genes involved in cardiac hypertrophy and cardiac beta-adrenergic receptor signaling and we showed reduced phosphorylation of cardiac troponin I in the HCM myocardium when compared with donor. HCM patients with MYBPC3 mutations have a specific miRNA expression profile. Downstream mRNA targets reveal possible involvement in cardiac signaling pathways. tissue_expression_ns hsa-mir-708 "Cardiomyopathy, Hypertrophic" 24083979 In silico identification of mRNA targets of differentially expressed miRNAs showed a large proportion of genes involved in cardiac hypertrophy and cardiac beta-adrenergic receptor signaling and we showed reduced phosphorylation of cardiac troponin I in the HCM myocardium when compared with donor. HCM patients with MYBPC3 mutations have a specific miRNA expression profile. Downstream mRNA targets reveal possible involvement in cardiac signaling pathways. tissue_expression_ns hsa-mir-96 "Cardiomyopathy, Hypertrophic" 24083979 In silico identification of mRNA targets of differentially expressed miRNAs showed a large proportion of genes involved in cardiac hypertrophy and cardiac beta-adrenergic receptor signaling and we showed reduced phosphorylation of cardiac troponin I in the HCM myocardium when compared with donor. HCM patients with MYBPC3 mutations have a specific miRNA expression profile. Downstream mRNA targets reveal possible involvement in cardiac signaling pathways. tissue_expression_ns hsa-mir-150 Traumatic Brain Injury 24108763 neutrophils associated with traumatic injury were found to have a unique miRNA signature. Changes in signaling pathways due to deregulated miRNAs may be involved in the pathological processes of traumatic injury. tissue_expression_ns hsa-mir-155 Traumatic Brain Injury 24108763 neutrophils associated with traumatic injury were found to have a unique miRNA signature. Changes in signaling pathways due to deregulated miRNAs may be involved in the pathological processes of traumatic injury. tissue_expression_ns hsa-mir-223 Traumatic Brain Injury 24108763 neutrophils associated with traumatic injury were found to have a unique miRNA signature. Changes in signaling pathways due to deregulated miRNAs may be involved in the pathological processes of traumatic injury. tissue_expression_ns hsa-mir-23a Traumatic Brain Injury 24108763 neutrophils associated with traumatic injury were found to have a unique miRNA signature. Changes in signaling pathways due to deregulated miRNAs may be involved in the pathological processes of traumatic injury. tissue_expression_ns hsa-mir-30e Traumatic Brain Injury 24108763 neutrophils associated with traumatic injury were found to have a unique miRNA signature. Changes in signaling pathways due to deregulated miRNAs may be involved in the pathological processes of traumatic injury. tissue_expression_ns hsa-mir-3945 Traumatic Brain Injury 24108763 neutrophils associated with traumatic injury were found to have a unique miRNA signature. Changes in signaling pathways due to deregulated miRNAs may be involved in the pathological processes of traumatic injury. tissue_expression_ns hsa-mir-124a "Carcinoma, Lung, Non-Small-Cell" 24113142 The developed prediction algorithm is a valuable potential biomarker for assisting lung cancer diagnosis in minimal biopsy material. A prospective validation is required to measure the enhancement of diagnostic accuracy of our current clinical practice. tissue_expression_ns hsa-mir-126 "Carcinoma, Lung, Non-Small-Cell" 24113142 The developed prediction algorithm is a valuable potential biomarker for assisting lung cancer diagnosis in minimal biopsy material. A prospective validation is required to measure the enhancement of diagnostic accuracy of our current clinical practice. tissue_expression_ns hsa-mir-200c "Carcinoma, Lung, Non-Small-Cell" 24113142 The developed prediction algorithm is a valuable potential biomarker for assisting lung cancer diagnosis in minimal biopsy material. A prospective validation is required to measure the enhancement of diagnostic accuracy of our current clinical practice. tissue_expression_ns hsa-mir-34 "Carcinoma, Lung, Non-Small-Cell" 24113142 The developed prediction algorithm is a valuable potential biomarker for assisting lung cancer diagnosis in minimal biopsy material. A prospective validation is required to measure the enhancement of diagnostic accuracy of our current clinical practice. tissue_expression_ns hsa-mir-9 "Carcinoma, Lung, Non-Small-Cell" 24113142 The developed prediction algorithm is a valuable potential biomarker for assisting lung cancer diagnosis in minimal biopsy material. A prospective validation is required to measure the enhancement of diagnostic accuracy of our current clinical practice. tissue_expression_ns hsa-mir-141 "Carcinoma, Renal Cell" 24129247 "Expression analysis of miR-141 or miR-200b accurately distinguished RCTs from normal renal tissues, oncocytoma from RCC and chRCC from oncocytoma. The diagnostic performance was confirmed in the validation set. Interestingly,miR-21, miR-141 and miR-155 expression levels showed prognostic significance in a univariate analysis." tissue_expression_ns hsa-mir-155 "Carcinoma, Renal Cell" 24129247 "Expression analysis of miR-141 or miR-200b accurately distinguished RCTs from normal renal tissues, oncocytoma from RCC and chRCC from oncocytoma. The diagnostic performance was confirmed in the validation set. Interestingly,miR-21, miR-141 and miR-155 expression levels showed prognostic significance in a univariate analysis." tissue_expression_ns hsa-mir-21 "Carcinoma, Renal Cell" 24129247 "Expression analysis of miR-141 or miR-200b accurately distinguished RCTs from normal renal tissues, oncocytoma from RCC and chRCC from oncocytoma. The diagnostic performance was confirmed in the validation set. Interestingly,miR-21, miR-141 and miR-155 expression levels showed prognostic significance in a univariate analysis." tissue_expression_ns hsa-mir-143 Vascular Disease [unspecific] 24166492 The flank sequences of miR-145 and miR-143 play a critical role in their aberrant expression in VSMCs and vascular walls. The genetically engineered smart miRNAs based on their flank sequences may have broadly therapeutic applications for many vascular diseases. tissue_expression_ns hsa-mir-145 Vascular Disease [unspecific] 24166492 The flank sequences of miR-145 and miR-143 play a critical role in their aberrant expression in VSMCs and vascular walls. The genetically engineered smart miRNAs based on their flank sequences may have broadly therapeutic applications for many vascular diseases. tissue_expression_ns hsa-mir-205 Prostate Neoplasms 24167554 MicroRNA profiling in prostate cancer--the diagnostic potential of urinary miR-205 and miR-214. tissue_expression_ns hsa-mir-214 Prostate Neoplasms 24167554 MicroRNA profiling in prostate cancer--the diagnostic potential of urinary miR-205 and miR-214. tissue_expression_ns hsa-mir-204 Breast Neoplasms 24191129 "The expression and the functional role of several miRNAs (miR-206, miR-31, miR-27a/b, miR-21, miR-92a, miR-205, miR-125a/b, miR-10b, miR-155, miR-146a/b, miR-335, miR-204, miR-211, miR-7, miR-22, miR-126, and miR-17) in breast cancer has been identified." tissue_expression_ns hsa-mir-10b Breast Neoplasms 24196612 microRNA expression in breast development and breast cancer] tissue_expression_ns hsa-mir-210 Breast Neoplasms 24196612 microRNA expression in breast development and breast cancer] tissue_expression_ns hsa-mir-31 Breast Neoplasms 24196612 microRNA expression in breast development and breast cancer] tissue_expression_ns hsa-mir-335 Breast Neoplasms 24196612 microRNA expression in breast development and breast cancer] tissue_expression_ns hsa-mir-1287 Laryngeal Neoplasms 24238754 Identification of predictive biomarkers for early diagnosis of larynx carcinoma based on microRNA expression data. tissue_expression_ns hsa-mir-657 Laryngeal Neoplasms 24238754 Identification of predictive biomarkers for early diagnosis of larynx carcinoma based on microRNA expression data. tissue_expression_ns hsa-mir-129 Psychiatric Disorders 24246224 Metabolic stress-induced microRNA and mRNA expression profiles of human fibroblasts. tissue_expression_ns hsa-mir-146b Psychiatric Disorders 24246224 Metabolic stress-induced microRNA and mRNA expression profiles of human fibroblasts. tissue_expression_ns hsa-mir-543 Psychiatric Disorders 24246224 Metabolic stress-induced microRNA and mRNA expression profiles of human fibroblasts. tissue_expression_ns hsa-mir-550a Psychiatric Disorders 24246224 Metabolic stress-induced microRNA and mRNA expression profiles of human fibroblasts. tissue_expression_ns hsa-let-7a "Carcinoma, Hepatocellular, HBV-Related" 24273923 Analysis of microRNA expression profiles in human hepatitis B virus-related hepatocellular carcinoma. tissue_expression_ns hsa-let-7c "Carcinoma, Hepatocellular, HBV-Related" 24273923 Analysis of microRNA expression profiles in human hepatitis B virus-related hepatocellular carcinoma. tissue_expression_ns hsa-mir-138 "Carcinoma, Hepatocellular, HBV-Related" 24273923 Analysis of microRNA expression profiles in human hepatitis B virus-related hepatocellular carcinoma. tissue_expression_ns hsa-mir-183 "Carcinoma, Hepatocellular, HBV-Related" 24273923 Analysis of microRNA expression profiles in human hepatitis B virus-related hepatocellular carcinoma. tissue_expression_ns hsa-mir-196a "Carcinoma, Hepatocellular, HBV-Related" 24273923 Analysis of microRNA expression profiles in human hepatitis B virus-related hepatocellular carcinoma. tissue_expression_ns hsa-mir-96 "Carcinoma, Hepatocellular, HBV-Related" 24273923 Analysis of microRNA expression profiles in human hepatitis B virus-related hepatocellular carcinoma. tissue_expression_ns hsa-mir-330 Neoplasms [unspecific] 24278004 MicroRNA-gene association as a prognostic biomarker in cancer exposes disease mechanisms. tissue_expression_ns hsa-mir-143 "Carcinoma, Lung, Non-Small-Cell" 24286416 "It is indicated that there is a potential for using miR-143 as a novel diagnostic biomarker for NSCLC. Moreover, miR-150 can be a highly accurate marker for differentiating adenocarcinoma from squamous cell carcinoma." tissue_expression_ns hsa-mir-150 "Carcinoma, Lung, Non-Small-Cell" 24286416 "It is indicated that there is a potential for using miR-143 as a novel diagnostic biomarker for NSCLC. Moreover, miR-150 can be a highly accurate marker for differentiating adenocarcinoma from squamous cell carcinoma." tissue_expression_ns hsa-let-7f Bronchopulmonary Dysplasia 24301780 MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-130b Bronchopulmonary Dysplasia 24301780 MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-141 Bronchopulmonary Dysplasia 24301780 MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-146b Bronchopulmonary Dysplasia 24301780 MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-21 Bronchopulmonary Dysplasia 24301780 MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-214 Bronchopulmonary Dysplasia 24301780 MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-29a Bronchopulmonary Dysplasia 24301780 MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-34a Bronchopulmonary Dysplasia 24301780 MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-382 Bronchopulmonary Dysplasia 24301780 MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-411 Bronchopulmonary Dysplasia 24301780 MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-431 Bronchopulmonary Dysplasia 24301780 MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-503 Bronchopulmonary Dysplasia 24301780 MicroRNA expression profiling studies on bronchopulmonary dysplasia: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-10b Pituitary Adenoma 24310454 "We established miRNA expression maps of non-functioning and gonadotropin-secreting pituitary adenomas. The most strongly differentially expressed genes were miR-124a and miR-31 in non-functioning pituitary adenomas, and miR-10b and miR-503 in gonadotropin-secreting pituitary adenomas." tissue_expression_ns hsa-mir-422a Pituitary Adenoma 24310454 "We established miRNA expression maps of non-functioning and gonadotropin-secreting pituitary adenomas. The most strongly differentially expressed genes were miR-124a and miR-31 in non-functioning pituitary adenomas, and miR-10b and miR-503 in gonadotropin-secreting pituitary adenomas." tissue_expression_ns hsa-mir-422b Pituitary Adenoma 24310454 "We established miRNA expression maps of non-functioning and gonadotropin-secreting pituitary adenomas. The most strongly differentially expressed genes were miR-124a and miR-31 in non-functioning pituitary adenomas, and miR-10b and miR-503 in gonadotropin-secreting pituitary adenomas." tissue_expression_ns hsa-mir-520b Pituitary Adenoma 24310454 "We established miRNA expression maps of non-functioning and gonadotropin-secreting pituitary adenomas. The most strongly differentially expressed genes were miR-124a and miR-31 in non-functioning pituitary adenomas, and miR-10b and miR-503 in gonadotropin-secreting pituitary adenomas." tissue_expression_ns hsa-mir-523 Pituitary Adenoma 24310454 "We established miRNA expression maps of non-functioning and gonadotropin-secreting pituitary adenomas. The most strongly differentially expressed genes were miR-124a and miR-31 in non-functioning pituitary adenomas, and miR-10b and miR-503 in gonadotropin-secreting pituitary adenomas." tissue_expression_ns hsa-mir-146b Thyroid Lymphoma 24327568 "Histotype-specific miRNA signatures can provide new insight into the molecular mechanisms of thyroid carcinogenesis. The tested 4-miRNA signature is a promising diagnostic tool for differentiating ATC from PTL and non-neoplastic MNG, even in the presence of scant material obtained from minimally invasive procedures." tissue_expression_ns hsa-mir-221 Thyroid Lymphoma 24327568 "Histotype-specific miRNA signatures can provide new insight into the molecular mechanisms of thyroid carcinogenesis. The tested 4-miRNA signature is a promising diagnostic tool for differentiating ATC from PTL and non-neoplastic MNG, even in the presence of scant material obtained from minimally invasive procedures." tissue_expression_ns hsa-mir-222 Thyroid Lymphoma 24327568 "Histotype-specific miRNA signatures can provide new insight into the molecular mechanisms of thyroid carcinogenesis. The tested 4-miRNA signature is a promising diagnostic tool for differentiating ATC from PTL and non-neoplastic MNG, even in the presence of scant material obtained from minimally invasive procedures." tissue_expression_ns hsa-mir-26a Thyroid Lymphoma 24327568 "Histotype-specific miRNA signatures can provide new insight into the molecular mechanisms of thyroid carcinogenesis. The tested 4-miRNA signature is a promising diagnostic tool for differentiating ATC from PTL and non-neoplastic MNG, even in the presence of scant material obtained from minimally invasive procedures." tissue_expression_ns hsa-let-7g "Carcinoma, Renal Cell, Clear-Cell" 24351440 "MicroRNA expression signatures of stage, grade, and progression in clear cell RCC." tissue_expression_ns hsa-mir-142 "Carcinoma, Renal Cell, Clear-Cell" 24351440 "MicroRNA expression signatures of stage, grade, and progression in clear cell RCC." tissue_expression_ns hsa-mir-204 "Carcinoma, Renal Cell, Clear-Cell" 24351440 "MicroRNA expression signatures of stage, grade, and progression in clear cell RCC." tissue_expression_ns hsa-mir-21 "Carcinoma, Renal Cell, Clear-Cell" 24351440 "MicroRNA expression signatures of stage, grade, and progression in clear cell RCC." tissue_expression_ns hsa-mir-424 "Carcinoma, Renal Cell, Clear-Cell" 24351440 "MicroRNA expression signatures of stage, grade, and progression in clear cell RCC." tissue_expression_ns hsa-mir-129-2 "Lymphoma, Large B-Cell" 24358187 MicroRNA profiling of primary cutaneous large B-cell lymphomas. tissue_expression_ns hsa-mir-214 "Lymphoma, Large B-Cell" 24358187 MicroRNA profiling of primary cutaneous large B-cell lymphomas. tissue_expression_ns hsa-mir-31 "Lymphoma, Large B-Cell" 24358187 MicroRNA profiling of primary cutaneous large B-cell lymphomas. tissue_expression_ns hsa-mir-9 "Lymphoma, Large B-Cell" 24358187 MicroRNA profiling of primary cutaneous large B-cell lymphomas. tissue_expression_ns hsa-mir-17 "Squamous Cell Carcinoma, Esophageal" 24360091 "miR-17, miR-18a, and miR-19a can serve as potential unfavorable prognostic biomarkers in ESCC which are associated with some clinicopathologic factors" tissue_expression_ns hsa-mir-18a "Squamous Cell Carcinoma, Esophageal" 24360091 "miR-17, miR-18a, and miR-19a can serve as potential unfavorable prognostic biomarkers in ESCC which are associated with some clinicopathologic factors" tissue_expression_ns hsa-mir-19a "Squamous Cell Carcinoma, Esophageal" 24360091 "miR-17, miR-18a, and miR-19a can serve as potential unfavorable prognostic biomarkers in ESCC which are associated with some clinicopathologic factors" tissue_expression_ns hsa-mir-141 "Carcinoma, Endometrial" 24363810 Aberrant microRNA expression in endometrial carcinoma using formalin-fixed paraffin-embedded (FFPE) tissues. tissue_expression_ns hsa-mir-182 "Carcinoma, Endometrial" 24363810 Aberrant microRNA expression in endometrial carcinoma using formalin-fixed paraffin-embedded (FFPE) tissues. tissue_expression_ns hsa-mir-200a "Carcinoma, Endometrial" 24363810 Aberrant microRNA expression in endometrial carcinoma using formalin-fixed paraffin-embedded (FFPE) tissues. tissue_expression_ns hsa-mir-200b "Carcinoma, Endometrial" 24363810 Aberrant microRNA expression in endometrial carcinoma using formalin-fixed paraffin-embedded (FFPE) tissues. tissue_expression_ns hsa-mir-205 "Carcinoma, Endometrial" 24363810 Aberrant microRNA expression in endometrial carcinoma using formalin-fixed paraffin-embedded (FFPE) tissues. tissue_expression_ns hsa-mir-1323 "Carcinoma, Nasopharyngeal" 24367666 Genome-wide analyses of radioresistance-associated miRNA expression profile in nasopharyngeal carcinoma using next generation deep sequencing. tissue_expression_ns hsa-mir-324 "Carcinoma, Nasopharyngeal" 24367666 Genome-wide analyses of radioresistance-associated miRNA expression profile in nasopharyngeal carcinoma using next generation deep sequencing. tissue_expression_ns hsa-mir-34c "Carcinoma, Nasopharyngeal" 24367666 Genome-wide analyses of radioresistance-associated miRNA expression profile in nasopharyngeal carcinoma using next generation deep sequencing. tissue_expression_ns hsa-mir-371a "Carcinoma, Nasopharyngeal" 24367666 Genome-wide analyses of radioresistance-associated miRNA expression profile in nasopharyngeal carcinoma using next generation deep sequencing. tissue_expression_ns hsa-mir-4501 "Carcinoma, Nasopharyngeal" 24367666 Genome-wide analyses of radioresistance-associated miRNA expression profile in nasopharyngeal carcinoma using next generation deep sequencing. tissue_expression_ns hsa-mir-93 "Carcinoma, Nasopharyngeal" 24367666 Genome-wide analyses of radioresistance-associated miRNA expression profile in nasopharyngeal carcinoma using next generation deep sequencing. tissue_expression_ns hsa-mir-145 Liposarcoma 24375455 MicroRNA expression profiles distinguish liposarcoma subtypes and implicate miR-145 and miR-451 as tumor suppressors. tissue_expression_ns hsa-mir-451 Liposarcoma 24375455 MicroRNA expression profiles distinguish liposarcoma subtypes and implicate miR-145 and miR-451 as tumor suppressors. tissue_expression_ns hsa-mir-135a Polycystic Ovarian Syndrome 24390626 Altered microRNA and gene expression in the follicular fluid of women with polycystic ovary syndrome. tissue_expression_ns hsa-mir-18b Polycystic Ovarian Syndrome 24390626 Altered microRNA and gene expression in the follicular fluid of women with polycystic ovary syndrome. tissue_expression_ns hsa-mir-32 Polycystic Ovarian Syndrome 24390626 Altered microRNA and gene expression in the follicular fluid of women with polycystic ovary syndrome. tissue_expression_ns hsa-mir-34c Polycystic Ovarian Syndrome 24390626 Altered microRNA and gene expression in the follicular fluid of women with polycystic ovary syndrome. tissue_expression_ns hsa-mir-9 Polycystic Ovarian Syndrome 24390626 Altered microRNA and gene expression in the follicular fluid of women with polycystic ovary syndrome. tissue_expression_ns hsa-mir-34a Glioblastoma 24412053 "Comparing miRNA expression between glioblastoma group and gliomas of grades I-III, 3 miRNAs (miR-10b, mir-34a and miR-101) showed different regulation statuses between high-grade and low-grade tumors." tissue_expression_ns hsa-mir-23b Myotonic Muscular Dystrophy 24412363 "The Mef2 transcription network is disrupted in myotonic dystrophy heart tissue,dramatically altering miRNA and mRNA expression." tissue_expression_ns hsa-mir-16 Parkinson Disease 24427314 "We identified a total of 761 genes and 24 miRNAs that were misregulated in the absence of LRRK2 when a false discovery rate of 0.2 was applied. Notably, most changes in gene expression were modest (i.e., <2 fold). By real-time quantitative RT-PCR, we confirmed the variations of selected genes (e.g., adra2, syt2, opalin) and miRNAs (e.g., miR-16, miR-25)." tissue_expression_ns hsa-mir-126 "Carcinoma, Renal Cell" 24428907 A combined expression level of miR-21 and miR-126 accurately predicted CSS in two independent RCC cohorts and seems feasible for clinical application in assessing prognosis. tissue_expression_ns hsa-mir-21 "Carcinoma, Renal Cell" 24428907 A combined expression level of miR-21 and miR-126 accurately predicted CSS in two independent RCC cohorts and seems feasible for clinical application in assessing prognosis. tissue_expression_ns hsa-mir-146a Liver Neoplasms 24431000 Aberrant miRNA expression response to UV irradiation in human liver cancer cells. tissue_expression_ns hsa-mir-21 Liver Neoplasms 24431000 Aberrant miRNA expression response to UV irradiation in human liver cancer cells. tissue_expression_ns hsa-mir-26a Liver Neoplasms 24431000 Aberrant miRNA expression response to UV irradiation in human liver cancer cells. tissue_expression_ns hsa-mir-34a Liver Neoplasms 24431000 Aberrant miRNA expression response to UV irradiation in human liver cancer cells. tissue_expression_ns hsa-let-7 Prostate Neoplasms 24431212 Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic. tissue_expression_ns hsa-mir-134 Prostate Neoplasms 24431212 Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic. tissue_expression_ns hsa-mir-138 Prostate Neoplasms 24431212 Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic. tissue_expression_ns hsa-mir-143 Prostate Neoplasms 24431212 Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic. tissue_expression_ns hsa-mir-155 Prostate Neoplasms 24431212 Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic. tissue_expression_ns hsa-mir-181c Prostate Neoplasms 24431212 Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic. tissue_expression_ns hsa-mir-181d Prostate Neoplasms 24431212 Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic. tissue_expression_ns hsa-mir-205 Prostate Neoplasms 24431212 Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic. tissue_expression_ns hsa-mir-34c Prostate Neoplasms 24431212 Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic. tissue_expression_ns hsa-mir-373 Prostate Neoplasms 24431212 Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic. tissue_expression_ns hsa-mir-10a Urinary Bladder Cancer 24439061 The role of microRNA profiling in prognosticating progression in Ta and T1 urinary bladder cancer. tissue_expression_ns hsa-mir-31 Urinary Bladder Cancer 24439061 The role of microRNA profiling in prognosticating progression in Ta and T1 urinary bladder cancer. tissue_expression_ns hsa-mir-10b Breast Neoplasms 24440078 Detection of miRNA expression in intact cells using activatable sensor oligonucleotides. tissue_expression_ns hsa-mir-10b Breast Neoplasms 24440980 "MiR-21, -155, -222 and -10b are reliable candidate biomarkers for detection of breast cancer." tissue_expression_ns hsa-mir-155 Breast Neoplasms 24440980 "MiR-21, -155, -222 and -10b are reliable candidate biomarkers for detection of breast cancer." tissue_expression_ns hsa-mir-21 Breast Neoplasms 24440980 "MiR-21, -155, -222 and -10b are reliable candidate biomarkers for detection of breast cancer." tissue_expression_ns hsa-mir-222 Breast Neoplasms 24440980 "MiR-21, -155, -222 and -10b are reliable candidate biomarkers for detection of breast cancer." tissue_expression_ns hsa-mir-150 "Carcinoma, Thyroid" 24443580 MicroRNA profile of poorly differentiated thyroid carcinomas: new diagnostic and prognostic insights. tissue_expression_ns hsa-mir-23b "Carcinoma, Thyroid" 24443580 MicroRNA profile of poorly differentiated thyroid carcinomas: new diagnostic and prognostic insights. tissue_expression_ns hsa-mir-10b "Carcinoma, Lung, Non-Small-Cell" 24448358 "Expression of miR-128, -10b, -502-3p and -192 differed between SCC and AC, and miR-128 and -192 - between NLP and NSCLC." tissue_expression_ns hsa-mir-128 "Carcinoma, Lung, Non-Small-Cell" 24448358 "Expression of miR-128, -10b, -502-3p and -192 differed between SCC and AC, and miR-128 and -192 - between NLP and NSCLC." tissue_expression_ns hsa-mir-192 "Carcinoma, Lung, Non-Small-Cell" 24448358 "Expression of miR-128, -10b, -502-3p and -192 differed between SCC and AC, and miR-128 and -192 - between NLP and NSCLC." tissue_expression_ns hsa-mir-502 "Carcinoma, Lung, Non-Small-Cell" 24448358 "Expression of miR-128, -10b, -502-3p and -192 differed between SCC and AC, and miR-128 and -192 - between NLP and NSCLC." tissue_expression_ns hsa-mir-662 "Carcinoma, Lung, Non-Small-Cell" 24448358 "Of these six miRNAs, miR-662, -192 and -192* were confirmed as prognostic in the independent SCC cohort." tissue_expression_ns hsa-let-7 Prostate Neoplasms 24452514 Comprehensive microRNA profiling of prostate cancer cells after ionizing radiation treatment. tissue_expression_ns hsa-mir-1 Prostate Neoplasms 24452514 Comprehensive microRNA profiling of prostate cancer cells after ionizing radiation treatment. tissue_expression_ns hsa-mir-106b Prostate Neoplasms 24452514 Comprehensive microRNA profiling of prostate cancer cells after ionizing radiation treatment. tissue_expression_ns hsa-mir-125b Prostate Neoplasms 24452514 Comprehensive microRNA profiling of prostate cancer cells after ionizing radiation treatment. tissue_expression_ns hsa-mir-205 Prostate Neoplasms 24452514 Comprehensive microRNA profiling of prostate cancer cells after ionizing radiation treatment. tissue_expression_ns hsa-mir-20a Prostate Neoplasms 24452514 Comprehensive microRNA profiling of prostate cancer cells after ionizing radiation treatment. tissue_expression_ns hsa-mir-21 Prostate Neoplasms 24452514 Comprehensive microRNA profiling of prostate cancer cells after ionizing radiation treatment. tissue_expression_ns hsa-mir-34a Prostate Neoplasms 24452514 Comprehensive microRNA profiling of prostate cancer cells after ionizing radiation treatment. tissue_expression_ns hsa-mir-521 Prostate Neoplasms 24452514 Comprehensive microRNA profiling of prostate cancer cells after ionizing radiation treatment. tissue_expression_ns hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 24460255 "the miR-155 expression level plays a prognostic role in patients with cancer, especially NSCLCs and digestive system carcinomas." tissue_expression_ns hsa-mir-1 Atrial Fibrillation 24461008 AF alters the miRNA expression profiles of the left atria of MS patients. These findings may be useful for the biological understanding of AF in MS patients. tissue_expression_ns hsa-mir-26a Atrial Fibrillation 24461008 AF alters the miRNA expression profiles of the left atria of MS patients. These findings may be useful for the biological understanding of AF in MS patients. tissue_expression_ns hsa-mir-3613 Atrial Fibrillation 24461008 AF alters the miRNA expression profiles of the left atria of MS patients. These findings may be useful for the biological understanding of AF in MS patients. tissue_expression_ns hsa-mir-466 Atrial Fibrillation 24461008 AF alters the miRNA expression profiles of the left atria of MS patients. These findings may be useful for the biological understanding of AF in MS patients. tissue_expression_ns hsa-mir-574 Atrial Fibrillation 24461008 AF alters the miRNA expression profiles of the left atria of MS patients. These findings may be useful for the biological understanding of AF in MS patients. tissue_expression_ns hsa-mir-146a Mycobacterium Avium Complex Disease 24462562 Analysis of miRNA expression profiling in human macrophages responding to Mycobacterium infection: induction of the immune regulator miR-146a. tissue_expression_ns hsa-mir-17 Leukemia 24479800 "Aberrant expression of oncogenic miRNAs, including miR-155, miR-17-92, miR-21, miR-125b, miR-93, miR-143-p3, miR-196b, and miR-223 promotes leukemogenesis through increasing the leukemic stem/progenitor cell population, promoting cell proliferation, blocking cell differentiation, and diminishing cell apoptosis." tissue_expression_ns hsa-mir-133 Polycystic Kidney Disease 24489795 "We found that in ADPKD urine specimens, miRNA previously implicated as kidney tumor suppressors (miR-1 and miR-133), as well as miRNA of presumed inflammatory and fibroblast cell origin (miR-223/miR-199), are dysregulated when compared to other CKD patients. Concordant with findings in the primary tubule epithelial cell model, this suggests roles for dysregulated miRNA in ADPKD pathogenesis and potential use as biomarkers. We intend to assess prognostic potential of miRNA in a followup analysis." tissue_expression_ns hsa-mir-143 Polycystic Kidney Disease 24489795 "We found that in ADPKD urine specimens, miRNA previously implicated as kidney tumor suppressors (miR-1 and miR-133), as well as miRNA of presumed inflammatory and fibroblast cell origin (miR-223/miR-199), are dysregulated when compared to other CKD patients. Concordant with findings in the primary tubule epithelial cell model, this suggests roles for dysregulated miRNA in ADPKD pathogenesis and potential use as biomarkers. We intend to assess prognostic potential of miRNA in a followup analysis." tissue_expression_ns hsa-mir-199 Polycystic Kidney Disease 24489795 "We found that in ADPKD urine specimens, miRNA previously implicated as kidney tumor suppressors (miR-1 and miR-133), as well as miRNA of presumed inflammatory and fibroblast cell origin (miR-223/miR-199), are dysregulated when compared to other CKD patients. Concordant with findings in the primary tubule epithelial cell model, this suggests roles for dysregulated miRNA in ADPKD pathogenesis and potential use as biomarkers. We intend to assess prognostic potential of miRNA in a followup analysis." tissue_expression_ns hsa-mir-205 Polycystic Kidney Disease 24489795 "We found that in ADPKD urine specimens, miRNA previously implicated as kidney tumor suppressors (miR-1 and miR-133), as well as miRNA of presumed inflammatory and fibroblast cell origin (miR-223/miR-199), are dysregulated when compared to other CKD patients. Concordant with findings in the primary tubule epithelial cell model, this suggests roles for dysregulated miRNA in ADPKD pathogenesis and potential use as biomarkers. We intend to assess prognostic potential of miRNA in a followup analysis." tissue_expression_ns hsa-mir-223 Polycystic Kidney Disease 24489795 "We found that in ADPKD urine specimens, miRNA previously implicated as kidney tumor suppressors (miR-1 and miR-133), as well as miRNA of presumed inflammatory and fibroblast cell origin (miR-223/miR-199), are dysregulated when compared to other CKD patients. Concordant with findings in the primary tubule epithelial cell model, this suggests roles for dysregulated miRNA in ADPKD pathogenesis and potential use as biomarkers. We intend to assess prognostic potential of miRNA in a followup analysis." tissue_expression_ns hsa-mir-141 Colorectal Carcinoma 24510588 "miR-200a, miR-200c, miR-141, and miR-429 expression levels may identify CRC patients, including those with stage II disease, who are most likely to benefit from adjuvant chemotherapy." tissue_expression_ns hsa-mir-200a Colorectal Carcinoma 24510588 "miR-200a, miR-200c, miR-141, and miR-429 expression levels may identify CRC patients, including those with stage II disease, who are most likely to benefit from adjuvant chemotherapy." tissue_expression_ns hsa-mir-200c Colorectal Carcinoma 24510588 "miR-200a, miR-200c, miR-141, and miR-429 expression levels may identify CRC patients, including those with stage II disease, who are most likely to benefit from adjuvant chemotherapy." tissue_expression_ns hsa-mir-128 Neoplasms [unspecific] 24515752 Microvesicle-associated microRNA expression is altered upon particulate matter exposure in healthy workers and in A549 cells. tissue_expression_ns hsa-mir-302c Neoplasms [unspecific] 24515752 Microvesicle-associated microRNA expression is altered upon particulate matter exposure in healthy workers and in A549 cells. tissue_expression_ns hsa-mir-143 "Carcinoma, Cervical" 24517947 "It seemed that miR-143 play an important role in the processes of generation and progression of cervical cancer. However, there was no significant difference found between the different ethnic groups. The expression level of miR-143 might serve as a valuable adjuvant parameter for diagnosing and predicting the state of cervical cancer." tissue_expression_ns hsa-mir-182 Prostate Neoplasms 24518785 Results show that miR-182 and 187 are promising biomarkers for prostate cancer prognosis to identify patients at risk for progression and for diagnosis to improve the predictive capability of existing biomarkers. tissue_expression_ns hsa-mir-187 Prostate Neoplasms 24518785 Results show that miR-182 and 187 are promising biomarkers for prostate cancer prognosis to identify patients at risk for progression and for diagnosis to improve the predictive capability of existing biomarkers. tissue_expression_ns hsa-mir-363 Colorectal Carcinoma 24519049 The expression pattern in female is different from that in male.miR-363 and miR-490-5p possess the potential in screening colorectal cancer patients from healthy people. tissue_expression_ns hsa-mir-490 Colorectal Carcinoma 24519049 The expression pattern in female is different from that in male.miR-363 and miR-490-5p possess the potential in screening colorectal cancer patients from healthy people. tissue_expression_ns hsa-mir-195 Bladder Neoplasms 24520312 The microRNA expression signature of bladder cancer by deep sequencing: the functional significance of the miR-195/497 cluster. tissue_expression_ns hsa-mir-497 Bladder Neoplasms 24520312 The microRNA expression signature of bladder cancer by deep sequencing: the functional significance of the miR-195/497 cluster. tissue_expression_ns hsa-mir-133a Neuroendocrine Tumors 24535468 Establishment of robust controls for the normalization of miRNA expression in neuroendocrine tumors of the ileum and pancreas. tissue_expression_ns hsa-mir-191 Neuroendocrine Tumors 24535468 Establishment of robust controls for the normalization of miRNA expression in neuroendocrine tumors of the ileum and pancreas. tissue_expression_ns hsa-mir-93 Neuroendocrine Tumors 24535468 Establishment of robust controls for the normalization of miRNA expression in neuroendocrine tumors of the ileum and pancreas. tissue_expression_ns hsa-mir-92a Colorectal Carcinoma 24551148 "MicroRNA-92a might be a novel potential biomarker in the diagnosis of colorectal cancer, and more studies are needed to highlight the theoretical strengths." tissue_expression_ns hsa-mir-155 Autoimmune Thyroiditis 24554510 microRNA expressions in CD4+ and CD8+ T-cell subsets in autoimmune thyroid diseases. tissue_expression_ns hsa-mir-200a Autoimmune Thyroiditis 24554510 microRNA expressions in CD4+ and CD8+ T-cell subsets in autoimmune thyroid diseases. tissue_expression_ns hsa-mir-196a "Carcinoma, Periampullary" 24555977 "Differentially expressed common miRNA signatures identified in PAC subgroups may have a role in pathogenesis of PAC and miR-375, miR-31 and miR-196a expression patterns may differentiate PAC subtypes." tissue_expression_ns hsa-mir-31 "Carcinoma, Periampullary" 24555977 "Differentially expressed common miRNA signatures identified in PAC subgroups may have a role in pathogenesis of PAC and miR-375, miR-31 and miR-196a expression patterns may differentiate PAC subtypes." tissue_expression_ns hsa-mir-375 "Carcinoma, Periampullary" 24555977 "Differentially expressed common miRNA signatures identified in PAC subgroups may have a role in pathogenesis of PAC and miR-375, miR-31 and miR-196a expression patterns may differentiate PAC subtypes." tissue_expression_ns hsa-mir-122 Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-140 Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-17 Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-18a Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-195 Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-210 Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-214 Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-221 Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-222 Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-223 Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-224 Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-34a Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-96 Hepatoblastoma 24570391 MicroRNA expression might predict prognosis of epithelial hepatoblastoma. tissue_expression_ns hsa-mir-155 Lung Neoplasms 24574164 "Under clinical conditions, mRNA detection is likely unsuitable for improving sensitivity of EBUS-TBNA-facilitated cancer staging. In contrast,detection of miRNA combined with EBUS-TBNA cytology may improve staging sensitivity." tissue_expression_ns hsa-mir-200c Lung Neoplasms 24574164 "Under clinical conditions, mRNA detection is likely unsuitable for improving sensitivity of EBUS-TBNA-facilitated cancer staging. In contrast,detection of miRNA combined with EBUS-TBNA cytology may improve staging sensitivity." tissue_expression_ns hsa-mir-21 Lung Neoplasms 24574164 "Under clinical conditions, mRNA detection is likely unsuitable for improving sensitivity of EBUS-TBNA-facilitated cancer staging. In contrast,detection of miRNA combined with EBUS-TBNA cytology may improve staging sensitivity." tissue_expression_ns hsa-mir-34a Lung Neoplasms 24574164 "Under clinical conditions, mRNA detection is likely unsuitable for improving sensitivity of EBUS-TBNA-facilitated cancer staging. In contrast,detection of miRNA combined with EBUS-TBNA cytology may improve staging sensitivity." tissue_expression_ns hsa-mir-100 "Adenocarcinoma, Pancreatic Ductal" 24575833 A microRNA meta-signature for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-143 "Adenocarcinoma, Pancreatic Ductal" 24575833 A microRNA meta-signature for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-148a "Adenocarcinoma, Pancreatic Ductal" 24575833 A microRNA meta-signature for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-155 "Adenocarcinoma, Pancreatic Ductal" 24575833 A microRNA meta-signature for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 24575833 A microRNA meta-signature for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-217 "Adenocarcinoma, Pancreatic Ductal" 24575833 A microRNA meta-signature for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-221 "Adenocarcinoma, Pancreatic Ductal" 24575833 A microRNA meta-signature for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-23a "Adenocarcinoma, Pancreatic Ductal" 24575833 A microRNA meta-signature for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-31 "Adenocarcinoma, Pancreatic Ductal" 24575833 A microRNA meta-signature for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-375 "Adenocarcinoma, Pancreatic Ductal" 24575833 A microRNA meta-signature for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-103 Early-Stage Gastric Carcinoma 24577775 Abnormal mirna expression level in early gastric cancer tissues may be associated to the development of gastric cancer. tissue_expression_ns hsa-mir-141 Early-Stage Gastric Carcinoma 24577775 Abnormal mirna expression level in early gastric cancer tissues may be associated to the development of gastric cancer. tissue_expression_ns hsa-mir-142 Early-Stage Gastric Carcinoma 24577775 Abnormal mirna expression level in early gastric cancer tissues may be associated to the development of gastric cancer. tissue_expression_ns hsa-mir-196a Early-Stage Gastric Carcinoma 24577775 Abnormal mirna expression level in early gastric cancer tissues may be associated to the development of gastric cancer. tissue_expression_ns hsa-mir-25 Early-Stage Gastric Carcinoma 24577775 Abnormal mirna expression level in early gastric cancer tissues may be associated to the development of gastric cancer. tissue_expression_ns hsa-mir-9-1 Early-Stage Gastric Carcinoma 24577775 Abnormal mirna expression level in early gastric cancer tissues may be associated to the development of gastric cancer. tissue_expression_ns hsa-mir-196b Tuberculosis 24586438 "The microRNA differential-expression profiles generated in this study provide a good foundation for the development of markers for TB diagnosis, and for investigations on the role of microRNAs in BCG-inoculated and latent-infected individuals." tissue_expression_ns hsa-mir-376c Tuberculosis 24586438 "The microRNA differential-expression profiles generated in this study provide a good foundation for the development of markers for TB diagnosis, and for investigations on the role of microRNAs in BCG-inoculated and latent-infected individuals." tissue_expression_ns hsa-mir-106a Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-107 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-141 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-187 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-195 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-200c Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-378 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-409 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-411 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-432 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-494 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-497 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-622 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-647 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-663 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-96 Ovarian Neoplasms 24591819 Differential microRNA expression signatures and cell type-specific association with Taxol resistance in ovarian cancer cells. tissue_expression_ns hsa-mir-432 "Carcinoma, Hepatocellular" 24592541 Our study firstly demonstrated that miRNAs were differentially expressed in HCC-MVs compared with CHB and normal controls. Aberrant HCC-MVs miRNAs may play important roles in the development of HCC. tissue_expression_ns hsa-mir-671 "Carcinoma, Hepatocellular" 24592541 Our study firstly demonstrated that miRNAs were differentially expressed in HCC-MVs compared with CHB and normal controls. Aberrant HCC-MVs miRNAs may play important roles in the development of HCC. tissue_expression_ns hsa-mir-182 "Squamous Cell Carcinoma, Lung" 24600991 We provide first time evidence through tissue microarray and quantitative PCR validation of mir-182 in the expression of lung squamous cell carcinoma. Our data provide a possible mechanism for lung cancer cell proliferation in lung squamous cell cancer and may be helpful in discovering a new strategy to reveal lung squamous cell carcinoma progress. tissue_expression_ns hsa-mir-222 "Diabetes Mellitus, Gestational" 24601884 Differential expression of microRNAs in omental adipose tissue from gestational diabetes mellitus subjects reveals miR-222 as a regulator of ER¦Á expression in estrogen-induced insulin resistance. tissue_expression_ns hsa-mir-25 "Adenocarcinoma, Lung" 24606441 Tissue miR-25 expression may be associated with tumor progression and have prognostic implications in female lung ADC patients. tissue_expression_ns hsa-mir-202 Endometriosis 24608518 "Differences in miRNA levels could modulate the expression of VEGF-A and TSP-1, which may play an important role in the pathogenesis of endometriosis. The higher angiogenic and proteolytic activities observed in eutopic endometrium from patients might facilitate the implantation of endometrial cells at ectopic sites." tissue_expression_ns hsa-mir-424 Endometriosis 24608518 "Differences in miRNA levels could modulate the expression of VEGF-A and TSP-1, which may play an important role in the pathogenesis of endometriosis. The higher angiogenic and proteolytic activities observed in eutopic endometrium from patients might facilitate the implantation of endometrial cells at ectopic sites." tissue_expression_ns hsa-mir-449b Endometriosis 24608518 "Differences in miRNA levels could modulate the expression of VEGF-A and TSP-1, which may play an important role in the pathogenesis of endometriosis. The higher angiogenic and proteolytic activities observed in eutopic endometrium from patients might facilitate the implantation of endometrial cells at ectopic sites." tissue_expression_ns hsa-mir-556 Endometriosis 24608518 "Differences in miRNA levels could modulate the expression of VEGF-A and TSP-1, which may play an important role in the pathogenesis of endometriosis. The higher angiogenic and proteolytic activities observed in eutopic endometrium from patients might facilitate the implantation of endometrial cells at ectopic sites." tissue_expression_ns hsa-mir-145 Neoplasms [unspecific] 24609385 "Together, our probabilistic approach of integrating expression and sequence scores establishes a functional link between the aberrant miRNA and mRNA expression, which was previously under-appreciated due to the methodological differences." tissue_expression_ns hsa-mir-155 Neoplasms [unspecific] 24609385 "Together, our probabilistic approach of integrating expression and sequence scores establishes a functional link between the aberrant miRNA and mRNA expression, which was previously under-appreciated due to the methodological differences." tissue_expression_ns hsa-mir-183 Neoplasms [unspecific] 24609385 "Together, our probabilistic approach of integrating expression and sequence scores establishes a functional link between the aberrant miRNA and mRNA expression, which was previously under-appreciated due to the methodological differences." tissue_expression_ns hsa-mir-21 Neoplasms [unspecific] 24609385 "Together, our probabilistic approach of integrating expression and sequence scores establishes a functional link between the aberrant miRNA and mRNA expression, which was previously under-appreciated due to the methodological differences." tissue_expression_ns hsa-mir-221 Neoplasms [unspecific] 24609385 "Together, our probabilistic approach of integrating expression and sequence scores establishes a functional link between the aberrant miRNA and mRNA expression, which was previously under-appreciated due to the methodological differences." tissue_expression_ns hsa-mir-222 Neoplasms [unspecific] 24609385 "Together, our probabilistic approach of integrating expression and sequence scores establishes a functional link between the aberrant miRNA and mRNA expression, which was previously under-appreciated due to the methodological differences." tissue_expression_ns hsa-mir-122 Hepatitis C Virus Infection 24612050 "However, a significant difference was observed in miR-122 expression between patients who showed a sustained virological response (SVR) and those who did not (Pâ€?â€?.05)." tissue_expression_ns hsa-mir-132 Gastric Neoplasms 24621117 miR-132 could serve as an efficient prognostic factor for gastric cancer patients. tissue_expression_ns hsa-mir-489 "Carcinoma, Renal Cell" 24621579 New miRNA profiles accurately distinguish renal cell carcinomas and upper tract urothelial carcinomas from the normal kidney. tissue_expression_ns hsa-mir-17 Breast Neoplasms 24626680 MicroRNA expression profiles in human breast cancer cells after multifraction and single-dose radiation treatment. tissue_expression_ns hsa-mir-18a Breast Neoplasms 24626680 MicroRNA expression profiles in human breast cancer cells after multifraction and single-dose radiation treatment. tissue_expression_ns hsa-mir-19a Breast Neoplasms 24626680 MicroRNA expression profiles in human breast cancer cells after multifraction and single-dose radiation treatment. tissue_expression_ns hsa-mir-19b Breast Neoplasms 24626680 MicroRNA expression profiles in human breast cancer cells after multifraction and single-dose radiation treatment. tissue_expression_ns hsa-mir-20a Breast Neoplasms 24626680 MicroRNA expression profiles in human breast cancer cells after multifraction and single-dose radiation treatment. tissue_expression_ns hsa-mir-92a Breast Neoplasms 24626680 MicroRNA expression profiles in human breast cancer cells after multifraction and single-dose radiation treatment. tissue_expression_ns hsa-mir-146b "Carcinoma, Thyroid, Follicular" 24631480 Differential miRNA expression defines migration and reduced apoptosis in follicular thyroid carcinomas. tissue_expression_ns hsa-mir-183 "Carcinoma, Thyroid, Follicular" 24631480 Differential miRNA expression defines migration and reduced apoptosis in follicular thyroid carcinomas. tissue_expression_ns hsa-mir-199b "Carcinoma, Thyroid, Follicular" 24631480 Differential miRNA expression defines migration and reduced apoptosis in follicular thyroid carcinomas. tissue_expression_ns hsa-mir-221 "Carcinoma, Thyroid, Follicular" 24631480 Differential miRNA expression defines migration and reduced apoptosis in follicular thyroid carcinomas. tissue_expression_ns hsa-mir-155 "Carcinoma, Breast, Triple Negative" 24632568 microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers. tissue_expression_ns hsa-mir-27a "Carcinoma, Breast, Triple Negative" 24632568 microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers. tissue_expression_ns hsa-mir-30e "Carcinoma, Breast, Triple Negative" 24632568 microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers. tissue_expression_ns hsa-mir-493 "Carcinoma, Breast, Triple Negative" 24632568 microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers. tissue_expression_ns hsa-mir-10a Breast Neoplasms 24632820 "In summary, we have identified a set of recurrence-related microRNAs with potential prognostic value to identify patients who will likely develop metastasis early after primary breast surgery." tissue_expression_ns hsa-mir-149 Breast Neoplasms 24632820 "In summary, we have identified a set of recurrence-related microRNAs with potential prognostic value to identify patients who will likely develop metastasis early after primary breast surgery." tissue_expression_ns hsa-mir-20b Breast Neoplasms 24632820 "In summary, we have identified a set of recurrence-related microRNAs with potential prognostic value to identify patients who will likely develop metastasis early after primary breast surgery." tissue_expression_ns hsa-mir-30a Breast Neoplasms 24632820 "In summary, we have identified a set of recurrence-related microRNAs with potential prognostic value to identify patients who will likely develop metastasis early after primary breast surgery." tissue_expression_ns hsa-mir-342 Breast Neoplasms 24632820 "In summary, we have identified a set of recurrence-related microRNAs with potential prognostic value to identify patients who will likely develop metastasis early after primary breast surgery." tissue_expression_ns hsa-mir-125b Hepatitis C Virus Infection 24637254 "PBMC-miR-125b expression levels were inversely related to the achievement of an SVR in HCV-1 patients, independent of interleukin-28B genotype,and was the single predictor of SVR in non-RVR patients." tissue_expression_ns hsa-mir-124 "Stroke, Hemorrhagic" 24650689 Both miR-124-3p and miR-16 are diagnostic markers to discriminate HS and IS. tissue_expression_ns hsa-mir-16 "Stroke, Hemorrhagic" 24650689 Both miR-124-3p and miR-16 are diagnostic markers to discriminate HS and IS. tissue_expression_ns hsa-mir-23a "Lymphoma, Large B-Cell, Diffuse" 24659264 MicroRNA-23a expression in paraffin-embedded specimen correlates with overall survival of diffuse large B-cell lymphoma. tissue_expression_ns hsa-mir-130b Pancreatic Neoplasms 24662333 "We developed and validated a 5-miRNA classifier that can accurately predict which preoperative pancreatic EUS-FNA specimens contain PDAC. This test might aid in the diagnosis of pancreatic cancer by reducing the number of FNAs without a definitive adenocarcinoma diagnosis, thereby reducing the number of repeat EUS-FNA procedures." tissue_expression_ns hsa-mir-135b Pancreatic Neoplasms 24662333 "We developed and validated a 5-miRNA classifier that can accurately predict which preoperative pancreatic EUS-FNA specimens contain PDAC. This test might aid in the diagnosis of pancreatic cancer by reducing the number of FNAs without a definitive adenocarcinoma diagnosis, thereby reducing the number of repeat EUS-FNA procedures." tissue_expression_ns hsa-mir-148a Pancreatic Neoplasms 24662333 "We developed and validated a 5-miRNA classifier that can accurately predict which preoperative pancreatic EUS-FNA specimens contain PDAC. This test might aid in the diagnosis of pancreatic cancer by reducing the number of FNAs without a definitive adenocarcinoma diagnosis, thereby reducing the number of repeat EUS-FNA procedures." tissue_expression_ns hsa-mir-196 Pancreatic Neoplasms 24662333 "We developed and validated a 5-miRNA classifier that can accurately predict which preoperative pancreatic EUS-FNA specimens contain PDAC. This test might aid in the diagnosis of pancreatic cancer by reducing the number of FNAs without a definitive adenocarcinoma diagnosis, thereby reducing the number of repeat EUS-FNA procedures." tissue_expression_ns hsa-mir-24 Pancreatic Neoplasms 24662333 "We developed and validated a 5-miRNA classifier that can accurately predict which preoperative pancreatic EUS-FNA specimens contain PDAC. This test might aid in the diagnosis of pancreatic cancer by reducing the number of FNAs without a definitive adenocarcinoma diagnosis, thereby reducing the number of repeat EUS-FNA procedures." tissue_expression_ns hsa-mir-125a Obesity 24675842 Adaptive expression of microRNA-125a in adipose tissue in response to obesity in mice and men. tissue_expression_ns hsa-mir-19a "Carcinoma, Supraglottic" 24676647 MicroRNA expression profiles in supraglottic carcinoma. tissue_expression_ns hsa-mir-206 "Carcinoma, Supraglottic" 24676647 MicroRNA expression profiles in supraglottic carcinoma. tissue_expression_ns hsa-mir-21 "Carcinoma, Supraglottic" 24676647 MicroRNA expression profiles in supraglottic carcinoma. tissue_expression_ns hsa-mir-33a "Carcinoma, Supraglottic" 24676647 MicroRNA expression profiles in supraglottic carcinoma. tissue_expression_ns hsa-mir-375 "Carcinoma, Supraglottic" 24676647 MicroRNA expression profiles in supraglottic carcinoma. tissue_expression_ns hsa-mir-30a "Carcinoma, Ovarian, Serous" 24676806 The expression of miR-30a* and miR-30e* is associated with a dualistic model for grading ovarian papillary serious carcinoma. tissue_expression_ns hsa-mir-30e "Carcinoma, Ovarian, Serous" 24676806 The expression of miR-30a* and miR-30e* is associated with a dualistic model for grading ovarian papillary serious carcinoma. tissue_expression_ns hsa-mir-21 "Carcinoma, Esophageal" 24680681 The expression of miR-21 and miR-375 predict prognosis of esophageal cancer. tissue_expression_ns hsa-mir-375 "Carcinoma, Esophageal" 24680681 The expression of miR-21 and miR-375 predict prognosis of esophageal cancer. tissue_expression_ns hsa-mir-125b-2 Recurrent Spontaneous Abortion 24686457 Genome-wide miRNA profiling of villus and decidua of recurrent spontaneous abortion patients. tissue_expression_ns hsa-mir-184 Recurrent Spontaneous Abortion 24686457 Genome-wide miRNA profiling of villus and decidua of recurrent spontaneous abortion patients. tissue_expression_ns hsa-mir-187 Recurrent Spontaneous Abortion 24686457 Genome-wide miRNA profiling of villus and decidua of recurrent spontaneous abortion patients. tissue_expression_ns hsa-mir-3175 Recurrent Spontaneous Abortion 24686457 Genome-wide miRNA profiling of villus and decidua of recurrent spontaneous abortion patients. tissue_expression_ns hsa-mir-4672 Recurrent Spontaneous Abortion 24686457 Genome-wide miRNA profiling of villus and decidua of recurrent spontaneous abortion patients. tissue_expression_ns hsa-mir-517c Recurrent Spontaneous Abortion 24686457 Genome-wide miRNA profiling of villus and decidua of recurrent spontaneous abortion patients. tissue_expression_ns hsa-mir-519a-1 Recurrent Spontaneous Abortion 24686457 Genome-wide miRNA profiling of villus and decidua of recurrent spontaneous abortion patients. tissue_expression_ns hsa-mir-520f Recurrent Spontaneous Abortion 24686457 Genome-wide miRNA profiling of villus and decidua of recurrent spontaneous abortion patients. tissue_expression_ns hsa-mir-520h Recurrent Spontaneous Abortion 24686457 Genome-wide miRNA profiling of villus and decidua of recurrent spontaneous abortion patients. tissue_expression_ns hsa-mir-522 Recurrent Spontaneous Abortion 24686457 Genome-wide miRNA profiling of villus and decidua of recurrent spontaneous abortion patients. tissue_expression_ns hsa-let-7d Glioblastoma 24691539 microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells. tissue_expression_ns hsa-mir-10a Glioblastoma 24691539 microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells. tissue_expression_ns hsa-mir-10b Glioblastoma 24691539 microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells. tissue_expression_ns hsa-mir-137 Glioblastoma 24691539 microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells. tissue_expression_ns hsa-mir-145 Glioblastoma 24691539 microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells. tissue_expression_ns hsa-mir-153 Glioblastoma 24691539 microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells. tissue_expression_ns hsa-mir-181b Glioblastoma 24691539 microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells. tissue_expression_ns hsa-mir-455 Glioblastoma 24691539 microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells. tissue_expression_ns hsa-mir-9 Glioblastoma 24691539 microRNA expression pattern modulates temozolomide response in GBM tumors with cancer stem cells. tissue_expression_ns hsa-mir-122 Hepatitis C Virus Infection 24696531 The study thus unveiled the role of miR-122 as a plausible diagnostic biomarker during HCV genotype-3 infection in India. tissue_expression_ns hsa-mir-215 "Carcinoma, Cervical" 24710934 "It was concluded that the expression level of miR-215 is associated with cervical tumor progression and worse survival rate, suggesting that it may serve as a potential prognostic marker to identify patients at higher risk of recurrence." tissue_expression_ns hsa-mir-210 Astrocytoma 24729345 "MiR-210 levels can be potentially established as a biomarker for pathological diagnosis of malignant astrocytic tumour progression. In addition,the expression of miR-210 can be utilized as an additional identification measure of glioma tumour origin." tissue_expression_ns hsa-mir-138 Colon Neoplasms 24732966 "miRs including mir-425, mir-196, mir-155, mir-150, mir-351, mir-16, let-7, mir34, and mir-138 were differentially expressed between the dietary groups." tissue_expression_ns hsa-mir-21 Uterine Corpus Serous Adenocarcinoma 24748979 microRNA expression patterns across seven cancers are highly correlated and dominated by evolutionarily ancient families. tissue_expression_ns hsa-mir-21 "Squamous Cell Carcinoma, Oral" 24755828 MiR-21 expression in the tumor stroma of oral squamous cell carcinoma: an independent biomarker of disease free survival. tissue_expression_ns hsa-mir-200a Obesity 24758184 "Taken together, our data indicate that the dysregulated expression of miRNAs occurs in distinct cell types and is likely to affect cell-specific function(s) of obese WAT." tissue_expression_ns hsa-mir-200b Obesity 24758184 "Taken together, our data indicate that the dysregulated expression of miRNAs occurs in distinct cell types and is likely to affect cell-specific function(s) of obese WAT." tissue_expression_ns hsa-mir-335 Obesity 24758184 "Taken together, our data indicate that the dysregulated expression of miRNAs occurs in distinct cell types and is likely to affect cell-specific function(s) of obese WAT." tissue_expression_ns hsa-mir-342 Obesity 24758184 "Taken together, our data indicate that the dysregulated expression of miRNAs occurs in distinct cell types and is likely to affect cell-specific function(s) of obese WAT." tissue_expression_ns hsa-mir-122 Varicella 24759212 Dysregulated microRNA expression in serum of non-vaccinated children with varicella. tissue_expression_ns hsa-mir-132 Varicella 24759212 Dysregulated microRNA expression in serum of non-vaccinated children with varicella. tissue_expression_ns hsa-mir-197 Varicella 24759212 Dysregulated microRNA expression in serum of non-vaccinated children with varicella. tissue_expression_ns hsa-mir-363 Varicella 24759212 Dysregulated microRNA expression in serum of non-vaccinated children with varicella. tissue_expression_ns hsa-mir-629 Varicella 24759212 Dysregulated microRNA expression in serum of non-vaccinated children with varicella. tissue_expression_ns hsa-mir-125a Post-Traumatic Stress Disorder 24759737 Dysregulation in microRNA expression is associated with alterations in immune functions in combat veterans with post-traumatic stress disorder. tissue_expression_ns hsa-mir-199a Keloid 24782087 Keloid microRNA expression analysis and the influence of miR-199a-5p on the proliferation of keloid fibroblasts. tissue_expression_ns hsa-mir-21 Perlman Syndrome 24786382 Our study is the first to investigate the association between placental miRNA expression and macrosomia. Our results indicate that the expression level of miR-21 in placental tissue may be involved in the development of macrosomia. tissue_expression_ns hsa-mir-145 "Adenocarcinoma, Colon" 24791633 "Differential expression of microRNA-320a, -145, and-192 along the continuum of normal mucosa to high-grade dysplastic adenomas of the colorectum." tissue_expression_ns hsa-mir-192 "Adenocarcinoma, Colon" 24791633 "Differential expression of microRNA-320a, -145, and-193 along the continuum of normal mucosa to high-grade dysplastic adenomas of the colorectum." tissue_expression_ns hsa-mir-320a "Adenocarcinoma, Colon" 24791633 "Differential expression of microRNA-320a, -145, and-194 along the continuum of normal mucosa to high-grade dysplastic adenomas of the colorectum." tissue_expression_ns hsa-mir-26a Multiple Sclerosis 24792898 "miR-326 and miR-26a, two potential markers for diagnosis of relapse and remission phases in patient with relapsing-remitting multiple sclerosis." tissue_expression_ns hsa-mir-326 Multiple Sclerosis 24792898 "miR-326 and miR-26a, two potential markers for diagnosis of relapse and remission phases in patient with relapsing-remitting multiple sclerosis." tissue_expression_ns hsa-mir-148a "Carcinoma, Hepatocellular" 24798342 microRNA-148a dysregulation discriminates poor prognosis of hepatocellular carcinoma in association with USP4 overexpression. tissue_expression_ns hsa-let-7a "Carcinoma, Lung, Non-Small-Cell" 24802132 "Before PRFA, tumor suppressor let-7a and miR-34a were downregulated whereas oncomiR miR-21 was upregulated in primary tumors, and let-7a and miR-126 levels were downregulated whereas oncomiRs miR-21, miR-155 and miR-17-5p/miR-20b levels were upregulated in secondary tumors." tissue_expression_ns hsa-mir-214 "Carcinoma, Hepatocellular" 24804874 "Among the analysed miRNAs, high miR-214 expression was associated with smaller tumor size (p=0.019), whereas high miR-17-5p expression correlated with better Eastern Cooperative Oncology Group performance status (p=0.003)." tissue_expression_ns hsa-mir-106b Ovarian Neoplasms 24805828 "The results obtained by miRNA microarrays of differential expression with hsa-miR-106b-3p, hsa-miR-152, hsa-miR-200a-3p, hsa-miR-381, and hsa-miR-429 were confirmed by real-time PCR." tissue_expression_ns hsa-mir-17 "Carcinoma, Breast, Triple Negative" 24810926 "Triple-negative and luminal A breast tumors: differential expression of miR-18a-5p, miR-17-5p, and miR-20a-5p." tissue_expression_ns hsa-mir-18a "Carcinoma, Breast, Triple Negative" 24810926 "Triple-negative and luminal A breast tumors: differential expression of miR-18a-5p, miR-17-5p, and miR-20a-5p." tissue_expression_ns hsa-mir-20a "Carcinoma, Breast, Triple Negative" 24810926 "Triple-negative and luminal A breast tumors: differential expression of miR-18a-5p, miR-17-5p, and miR-20a-5p." tissue_expression_ns hsa-mir-1271 "Carcinoma, Ovarian" 24816756 A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer. tissue_expression_ns hsa-mir-130b "Carcinoma, Ovarian" 24816756 A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer. tissue_expression_ns hsa-mir-135b "Carcinoma, Ovarian" 24816756 A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer. tissue_expression_ns hsa-mir-141 "Carcinoma, Ovarian" 24816756 A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer. tissue_expression_ns hsa-mir-15b "Carcinoma, Ovarian" 24816756 A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer. tissue_expression_ns hsa-mir-182 "Carcinoma, Ovarian" 24816756 A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer. tissue_expression_ns hsa-mir-183 "Carcinoma, Ovarian" 24816756 A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer. tissue_expression_ns hsa-mir-574 "Carcinoma, Ovarian" 24816756 A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer. tissue_expression_ns hsa-mir-96 "Carcinoma, Ovarian" 24816756 A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer. tissue_expression_ns hsa-mir-106a Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-106b Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-144 Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-15b Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-19 Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-208a Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-23a Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-25 Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-30a Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-363 Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-451 Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-486 Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-590 Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-93 Atrial Fibrillation 24824214 Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. tissue_expression_ns hsa-mir-338 Colorectal Carcinoma 24824250 Relationship between miRNA-338-3p expression and progression and prognosis of human colorectal carcinoma. tissue_expression_ns hsa-mir-155 Neoplasms [unspecific] 24824925 miR-155 as a diagnostic and prognostic marker in hematological and solid malignancies tissue_expression_ns hsa-mir-370 "Adenocarcinoma, Lung" 24833665 "Different morphologic subtypes of lung AC have distinct miRNA expression profiles, and 3 miRNAs encoded at 14q32 (miR-411, miR-370, and miR-376a) were associated with poor survival after lung AC resection." tissue_expression_ns hsa-mir-376a "Adenocarcinoma, Lung" 24833665 "Different morphologic subtypes of lung AC have distinct miRNA expression profiles, and 3 miRNAs encoded at 14q32 (miR-411, miR-370, and miR-376a) were associated with poor survival after lung AC resection." tissue_expression_ns hsa-mir-411 "Adenocarcinoma, Lung" 24833665 "Different morphologic subtypes of lung AC have distinct miRNA expression profiles, and 3 miRNAs encoded at 14q32 (miR-411, miR-370, and miR-376a) were associated with poor survival after lung AC resection." tissue_expression_ns hsa-mir-146a Pancreatic Neoplasms 24839931 Deregulation of miR-146a expression in a mouse model of pancreatic cancer affecting EGFR signaling. tissue_expression_ns hsa-mir-142 Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-185 Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-191 Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-200a Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-200b Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-206 Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-29b Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-30c Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-3196 Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-339 Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-3923 Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-421 Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-451 Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-542 Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-564 Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-92a Breast Neoplasms 24846313 miRNA expression in breast cancer varies with lymph node metastasis and other clinicopathologic features. tissue_expression_ns hsa-mir-21 Lung Neoplasms 24880588 Diagnostic value of microRNA-21 in the diagnosis of lung cancer: evidence from a meta-analysis involving 11 studies. tissue_expression_ns hsa-mir-324 "Carcinoma, Colon" 24882011 Dysregulation of the miR-324-5p-CUEDC2 axis leads to macrophage dysfunction and is associated with colon cancer. tissue_expression_ns hsa-mir-195 "Carcinoma, Adrenocortical" 24890943 "In conclusion, (a) miR-483-3p, miR-483-5p, and miR-210 are differentially expressed in ACC variants, and (b) high miR-210 is associated with clinicopathologic parameters of aggressiveness and a poor prognosis." tissue_expression_ns hsa-mir-1974 "Carcinoma, Adrenocortical" 24890943 "In conclusion, (a) miR-483-3p, miR-483-5p, and miR-210 are differentially expressed in ACC variants, and (b) high miR-210 is associated with clinicopathologic parameters of aggressiveness and a poor prognosis." tissue_expression_ns hsa-mir-210 "Carcinoma, Adrenocortical" 24890943 "In conclusion, (a) miR-483-3p, miR-483-5p, and miR-210 are differentially expressed in ACC variants, and (b) high miR-210 is associated with clinicopathologic parameters of aggressiveness and a poor prognosis." tissue_expression_ns hsa-mir-483 "Carcinoma, Adrenocortical" 24890943 "In conclusion, (a) miR-483-3p, miR-483-5p, and miR-210 are differentially expressed in ACC variants, and (b) high miR-210 is associated with clinicopathologic parameters of aggressiveness and a poor prognosis." tissue_expression_ns hsa-mir-21 Muscle Atrophy 24891504 "Among the different miRNAs, microRNA-206 and -21 were the most induced in denervated muscles." tissue_expression_ns hsa-mir-101-1 "Adenocarcinoma, Lung" 24893932 "We identified an eight-miRNA signature that is prognostic of LUAD.The miRNA signature, if validated in other prospective studies, may have important implications in clinical practice, in particular identifying a subgroup of patients with LUAD who are at high risk of mortality." tissue_expression_ns hsa-mir-187 "Adenocarcinoma, Lung" 24893932 "We identified an eight-miRNA signature that is prognostic of LUAD.The miRNA signature, if validated in other prospective studies, may have important implications in clinical practice, in particular identifying a subgroup of patients with LUAD who are at high risk of mortality." tissue_expression_ns hsa-mir-196b "Adenocarcinoma, Lung" 24893932 "We identified an eight-miRNA signature that is prognostic of LUAD.The miRNA signature, if validated in other prospective studies, may have important implications in clinical practice, in particular identifying a subgroup of patients with LUAD who are at high risk of mortality." tissue_expression_ns hsa-mir-31 "Adenocarcinoma, Lung" 24893932 "We identified an eight-miRNA signature that is prognostic of LUAD.The miRNA signature, if validated in other prospective studies, may have important implications in clinical practice, in particular identifying a subgroup of patients with LUAD who are at high risk of mortality." tissue_expression_ns hsa-mir-331 "Adenocarcinoma, Lung" 24893932 "We identified an eight-miRNA signature that is prognostic of LUAD.The miRNA signature, if validated in other prospective studies, may have important implications in clinical practice, in particular identifying a subgroup of patients with LUAD who are at high risk of mortality." tissue_expression_ns hsa-mir-375 "Adenocarcinoma, Lung" 24893932 "We identified an eight-miRNA signature that is prognostic of LUAD.The miRNA signature, if validated in other prospective studies, may have important implications in clinical practice, in particular identifying a subgroup of patients with LUAD who are at high risk of mortality." tissue_expression_ns hsa-mir-519a-1 "Adenocarcinoma, Lung" 24893932 "We identified an eight-miRNA signature that is prognostic of LUAD.The miRNA signature, if validated in other prospective studies, may have important implications in clinical practice, in particular identifying a subgroup of patients with LUAD who are at high risk of mortality." tissue_expression_ns hsa-mir-766 "Adenocarcinoma, Lung" 24893932 "We identified an eight-miRNA signature that is prognostic of LUAD.The miRNA signature, if validated in other prospective studies, may have important implications in clinical practice, in particular identifying a subgroup of patients with LUAD who are at high risk of mortality." tissue_expression_ns hsa-mir-5000 "Carcinoma, Colon" 24898979 "MiR-5000-3p, miR-5009-3P and miR-552: potential microRNA biomarkers of side population cells in colon cancer." tissue_expression_ns hsa-mir-5009 "Carcinoma, Colon" 24898979 "MiR-5000-3p, miR-5009-3P and miR-552: potential microRNA biomarkers of side population cells in colon cancer." tissue_expression_ns hsa-mir-552 "Carcinoma, Colon" 24898979 "MiR-5000-3p, miR-5009-3P and miR-552: potential microRNA biomarkers of side population cells in colon cancer." tissue_expression_ns hsa-mir-103 Gastric Neoplasms 24902858 This systematic review study of human GC microRNA expression profiling studies would provide information on microRNAs with potential role as the biomarkers in gastric cancer. tissue_expression_ns hsa-mir-107 Gastric Neoplasms 24902858 This systematic review study of human GC microRNA expression profiling studies would provide information on microRNAs with potential role as the biomarkers in gastric cancer. tissue_expression_ns hsa-mir-148a Gastric Neoplasms 24902858 This systematic review study of human GC microRNA expression profiling studies would provide information on microRNAs with potential role as the biomarkers in gastric cancer. tissue_expression_ns hsa-mir-21 Gastric Neoplasms 24902858 This systematic review study of human GC microRNA expression profiling studies would provide information on microRNAs with potential role as the biomarkers in gastric cancer. tissue_expression_ns hsa-mir-223 Gastric Neoplasms 24902858 This systematic review study of human GC microRNA expression profiling studies would provide information on microRNAs with potential role as the biomarkers in gastric cancer. tissue_expression_ns hsa-mir-25 Gastric Neoplasms 24902858 This systematic review study of human GC microRNA expression profiling studies would provide information on microRNAs with potential role as the biomarkers in gastric cancer. tissue_expression_ns hsa-mir-375 Gastric Neoplasms 24902858 This systematic review study of human GC microRNA expression profiling studies would provide information on microRNAs with potential role as the biomarkers in gastric cancer. tissue_expression_ns hsa-mir-638 Gastric Neoplasms 24902858 This systematic review study of human GC microRNA expression profiling studies would provide information on microRNAs with potential role as the biomarkers in gastric cancer. tissue_expression_ns hsa-mir-92 Gastric Neoplasms 24902858 This systematic review study of human GC microRNA expression profiling studies would provide information on microRNAs with potential role as the biomarkers in gastric cancer. tissue_expression_ns hsa-mir-195 "Adenocarcinoma, Lung" 24903339 Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features. tissue_expression_ns hsa-mir-30d "Adenocarcinoma, Lung" 24903339 Lung adenocarcinoma subtypes definable by lung development-related miRNA expression profiles in association with clinicopathologic features. tissue_expression_ns hsa-mir-124 Crohn Disease 24910152 Both inflamed and non-inflamed terminal ileal mucosa in adult patients with active CD have their distinct miRNA expression patterns compared with healthy controls. Dysregulated miRNAs may be responsible for pathogenesis of CD. tissue_expression_ns hsa-mir-192 Crohn Disease 24910152 Both inflamed and non-inflamed terminal ileal mucosa in adult patients with active CD have their distinct miRNA expression patterns compared with healthy controls. Dysregulated miRNAs may be responsible for pathogenesis of CD. tissue_expression_ns hsa-mir-361 Crohn Disease 24910152 Both inflamed and non-inflamed terminal ileal mucosa in adult patients with active CD have their distinct miRNA expression patterns compared with healthy controls. Dysregulated miRNAs may be responsible for pathogenesis of CD. tissue_expression_ns hsa-mir-495 Crohn Disease 24910152 Both inflamed and non-inflamed terminal ileal mucosa in adult patients with active CD have their distinct miRNA expression patterns compared with healthy controls. Dysregulated miRNAs may be responsible for pathogenesis of CD. tissue_expression_ns hsa-mir-126 Pleural Mesothelioma 24912849 "Diagnostic potential of miR-126, miR-143, miR-145, and miR-652 in malignant pleural mesothelioma." tissue_expression_ns hsa-mir-221 Acute Liver Failure 24913549 "In liver biopsies, miR-21 and miR-221 displayed a reciprocal expression pattern and were found at lower levels in the spontaneous survivors, whereas miR-122 was elevated in both serum and liver tissue of those patients." tissue_expression_ns hsa-mir-1248 Breast Neoplasms 24917463 "we identified miRNA expression signatures predictive of BRCA1/2 mutation status in routinely available FFPE breast tumor samples, which may be useful to complement current patient selection criteria for gene testing by identifying individuals with high likelihood of being BRCA1/2 mutation carriers." tissue_expression_ns hsa-mir-142 Breast Neoplasms 24917463 "we identified miRNA expression signatures predictive of BRCA1/2 mutation status in routinely available FFPE breast tumor samples, which may be useful to complement current patient selection criteria for gene testing by identifying individuals with high likelihood of being BRCA1/2 mutation carriers." tissue_expression_ns hsa-mir-181a-2 Breast Neoplasms 24917463 "we identified miRNA expression signatures predictive of BRCA1/2 mutation status in routinely available FFPE breast tumor samples, which may be useful to complement current patient selection criteria for gene testing by identifying individuals with high likelihood of being BRCA1/2 mutation carriers." tissue_expression_ns hsa-mir-25 Breast Neoplasms 24917463 "we identified miRNA expression signatures predictive of BRCA1/2 mutation status in routinely available FFPE breast tumor samples, which may be useful to complement current patient selection criteria for gene testing by identifying individuals with high likelihood of being BRCA1/2 mutation carriers." tissue_expression_ns hsa-mir-340 Breast Neoplasms 24917463 "we identified miRNA expression signatures predictive of BRCA1/2 mutation status in routinely available FFPE breast tumor samples, which may be useful to complement current patient selection criteria for gene testing by identifying individuals with high likelihood of being BRCA1/2 mutation carriers." tissue_expression_ns hsa-mir-505 Breast Neoplasms 24917463 "we identified miRNA expression signatures predictive of BRCA1/2 mutation status in routinely available FFPE breast tumor samples, which may be useful to complement current patient selection criteria for gene testing by identifying individuals with high likelihood of being BRCA1/2 mutation carriers." tissue_expression_ns hsa-mir-205 Colorectal Carcinoma 24935592 Diagnostic and prognostic value of miR-205 in colorectal cancer. tissue_expression_ns hsa-mir-138 Colon Neoplasms 24941171 This is the first to reveal the importance of aberrant expression of miRNAs in dynamically transformation from chronic colitis to colitis-associated cancer. These findings shed light on revealing the mechanisms of chronic colitis malignant transformation. tissue_expression_ns hsa-mir-145 Colon Neoplasms 24941171 This is the first to reveal the importance of aberrant expression of miRNAs in dynamically transformation from chronic colitis to colitis-associated cancer. These findings shed light on revealing the mechanisms of chronic colitis malignant transformation. tissue_expression_ns hsa-mir-146a Colon Neoplasms 24941171 This is the first to reveal the importance of aberrant expression of miRNAs in dynamically transformation from chronic colitis to colitis-associated cancer. These findings shed light on revealing the mechanisms of chronic colitis malignant transformation. tissue_expression_ns hsa-mir-150 Colon Neoplasms 24941171 This is the first to reveal the importance of aberrant expression of miRNAs in dynamically transformation from chronic colitis to colitis-associated cancer. These findings shed light on revealing the mechanisms of chronic colitis malignant transformation. tissue_expression_ns hsa-let-7e "Carcinoma, Lung, Non-Small-Cell" 24945821 Differential expression of miR-125a-5p and let-7e predicts the progression and prognosis of non-small cell lung cancer. tissue_expression_ns hsa-mir-125a "Carcinoma, Lung, Non-Small-Cell" 24945821 Differential expression of miR-125a-5p and let-7e predicts the progression and prognosis of non-small cell lung cancer. tissue_expression_ns hsa-mir-1 Prostate Neoplasms 24967583 miR-1 and miR-133b are differentially expressed in patients with recurrent prostate cancer. tissue_expression_ns hsa-mir-133b Prostate Neoplasms 24967583 miR-1 and miR-133b are differentially expressed in patients with recurrent prostate cancer. tissue_expression_ns hsa-mir-101 Hepatitis B Virus Infection 24971953 "Expression profiling of serum microRNA-101 in HBV-associated chronic hepatitis,liver cirrhosis, and hepatocellular carcinoma." tissue_expression_ns hsa-mir-143 Neoplasms [unspecific] 24974841 Using microRNA expression profiles the authors were able to distinguish peritumoural tissues according to distance from the primary tumour site. Future application of the method may prove to be useful in early detection of the altered epigenetic regulation in tissue fields representing normal phenotype. This may be helpful in cancer risk assessment and prevention. tissue_expression_ns hsa-mir-155 Neoplasms [unspecific] 24974841 Using microRNA expression profiles the authors were able to distinguish peritumoural tissues according to distance from the primary tumour site. Future application of the method may prove to be useful in early detection of the altered epigenetic regulation in tissue fields representing normal phenotype. This may be helpful in cancer risk assessment and prevention. tissue_expression_ns hsa-mir-21 Neoplasms [unspecific] 24974841 Using microRNA expression profiles the authors were able to distinguish peritumoural tissues according to distance from the primary tumour site. Future application of the method may prove to be useful in early detection of the altered epigenetic regulation in tissue fields representing normal phenotype. This may be helpful in cancer risk assessment and prevention. tissue_expression_ns hsa-mir-221 Neoplasms [unspecific] 24974841 Using microRNA expression profiles the authors were able to distinguish peritumoural tissues according to distance from the primary tumour site. Future application of the method may prove to be useful in early detection of the altered epigenetic regulation in tissue fields representing normal phenotype. This may be helpful in cancer risk assessment and prevention. tissue_expression_ns hsa-mir-106a "Carcinoma, Renal Cell" 24977165 Exploring the miRNA-mRNA regulatory network in clear cell renal cell carcinomas by next-generation sequencing expression profiles. tissue_expression_ns hsa-mir-135a "Carcinoma, Renal Cell" 24977165 Exploring the miRNA-mRNA regulatory network in clear cell renal cell carcinomas by next-generation sequencing expression profiles. tissue_expression_ns hsa-mir-142 "Carcinoma, Renal Cell" 24977165 Exploring the miRNA-mRNA regulatory network in clear cell renal cell carcinomas by next-generation sequencing expression profiles. tissue_expression_ns hsa-mir-206 "Carcinoma, Renal Cell" 24977165 Exploring the miRNA-mRNA regulatory network in clear cell renal cell carcinomas by next-generation sequencing expression profiles. tissue_expression_ns hsa-mir-21 "Carcinoma, Renal Cell" 24977165 Exploring the miRNA-mRNA regulatory network in clear cell renal cell carcinomas by next-generation sequencing expression profiles. tissue_expression_ns hsa-mir-216b "Carcinoma, Renal Cell" 24977165 Exploring the miRNA-mRNA regulatory network in clear cell renal cell carcinomas by next-generation sequencing expression profiles. tissue_expression_ns hsa-mir-3065 "Carcinoma, Renal Cell" 24977165 Exploring the miRNA-mRNA regulatory network in clear cell renal cell carcinomas by next-generation sequencing expression profiles. tissue_expression_ns hsa-mir-363 "Carcinoma, Renal Cell" 24977165 Exploring the miRNA-mRNA regulatory network in clear cell renal cell carcinomas by next-generation sequencing expression profiles. tissue_expression_ns hsa-mir-1244 Pallister-Killian Syndrome 24981202 12p microRNA expression in fibroblast cell lines from probands with Pallister-Killian syndrome. tissue_expression_ns hsa-mir-202 Multiple System Atrophy 24981430 Altered expression of miR-202 in cerebellum of multiple-system atrophy. tissue_expression_ns hsa-mir-125b Bladder Neoplasms 25014919 "The results revealed a unique microRNA expression signature in the urine supernatants of UCB patients for the development of molecular diagnostic tests. An effective cell-free urinary microRNA-based model was developed using a combined index of the levels of microRNA-99a and microRNA-125b to detect UCB with good discriminating power, high sensitivity and high specificity." tissue_expression_ns hsa-mir-99a Bladder Neoplasms 25014919 "The results revealed a unique microRNA expression signature in the urine supernatants of UCB patients for the development of molecular diagnostic tests. An effective cell-free urinary microRNA-based model was developed using a combined index of the levels of microRNA-99a and microRNA-125b to detect UCB with good discriminating power, high sensitivity and high specificity." tissue_expression_ns hsa-mir-195 Colorectal Carcinoma 25027346 "The 15 differentially expressed miRNAs, especially hsa-miR-195 and hsa-miR-20a may be used as potential biomarkers for early detection and screening of colorectal cancer." tissue_expression_ns hsa-mir-20a Colorectal Carcinoma 25027346 "The 15 differentially expressed miRNAs, especially hsa-miR-195 and hsa-miR-20a may be used as potential biomarkers for early detection and screening of colorectal cancer." tissue_expression_ns hsa-let-7b "Adenocarcinoma, Lung" 25028925 "The most significant differences in mRNA expression for recurrent tumors compared to non-recurrent tumors were decreases in miR-106b*, -187, -205, -449b, -774* and increases in miR-151-3p, let-7b, miR-215, -520b, and -512-3p." tissue_expression_ns hsa-mir-106b "Adenocarcinoma, Lung" 25028925 "The most significant differences in mRNA expression for recurrent tumors compared to non-recurrent tumors were decreases in miR-106b*, -187, -205, -449b, -774* and increases in miR-151-3p, let-7b, miR-215, -520b, and -512-3p." tissue_expression_ns hsa-mir-151a "Adenocarcinoma, Lung" 25028925 "The most significant differences in mRNA expression for recurrent tumors compared to non-recurrent tumors were decreases in miR-106b*, -187, -205, -449b, -774* and increases in miR-151-3p, let-7b, miR-215, -520b, and -512-3p." tissue_expression_ns hsa-mir-187 "Adenocarcinoma, Lung" 25028925 "The most significant differences in mRNA expression for recurrent tumors compared to non-recurrent tumors were decreases in miR-106b*, -187, -205, -449b, -774* and increases in miR-151-3p, let-7b, miR-215, -520b, and -512-3p." tissue_expression_ns hsa-mir-205 "Adenocarcinoma, Lung" 25028925 "The most significant differences in mRNA expression for recurrent tumors compared to non-recurrent tumors were decreases in miR-106b*, -187, -205, -449b, -774* and increases in miR-151-3p, let-7b, miR-215, -520b, and -512-3p." tissue_expression_ns hsa-mir-215 "Adenocarcinoma, Lung" 25028925 "The most significant differences in mRNA expression for recurrent tumors compared to non-recurrent tumors were decreases in miR-106b*, -187, -205, -449b, -774* and increases in miR-151-3p, let-7b, miR-215, -520b, and -512-3p." tissue_expression_ns hsa-mir-449b "Adenocarcinoma, Lung" 25028925 "The most significant differences in mRNA expression for recurrent tumors compared to non-recurrent tumors were decreases in miR-106b*, -187, -205, -449b, -774* and increases in miR-151-3p, let-7b, miR-215, -520b, and -512-3p." tissue_expression_ns hsa-mir-512 "Adenocarcinoma, Lung" 25028925 "The most significant differences in mRNA expression for recurrent tumors compared to non-recurrent tumors were decreases in miR-106b*, -187, -205, -449b, -774* and increases in miR-151-3p, let-7b, miR-215, -520b, and -512-3p." tissue_expression_ns hsa-mir-520b "Adenocarcinoma, Lung" 25028925 "The most significant differences in mRNA expression for recurrent tumors compared to non-recurrent tumors were decreases in miR-106b*, -187, -205, -449b, -774* and increases in miR-151-3p, let-7b, miR-215, -520b, and -512-3p." tissue_expression_ns hsa-mir-774 "Adenocarcinoma, Lung" 25028925 "The most significant differences in mRNA expression for recurrent tumors compared to non-recurrent tumors were decreases in miR-106b*, -187, -205, -449b, -774* and increases in miR-151-3p, let-7b, miR-215, -520b, and -512-3p." tissue_expression_ns hsa-mir-204 Breast Neoplasms 25031750 the miR-204 may be a potential diagnostic and prognostic biomarker of breast cancer. tissue_expression_ns hsa-let-7g "Squamous Cell Carcinoma, Oral" 25050621 "MicroRNAs MiR-218, MiR-125b, and Let-7g predict prognosis in patients with oral cavity squamous cell carcinoma." tissue_expression_ns hsa-mir-125b "Squamous Cell Carcinoma, Oral" 25050621 "MicroRNAs MiR-218, MiR-125b, and Let-7g predict prognosis in patients with oral cavity squamous cell carcinoma." tissue_expression_ns hsa-mir-218 "Squamous Cell Carcinoma, Oral" 25050621 "MicroRNAs MiR-218, MiR-125b, and Let-7g predict prognosis in patients with oral cavity squamous cell carcinoma." tissue_expression_ns hsa-mir-126 Prolactinoma 25064468 Our study is the first to identify a miRNA expression profile associated with bromocriptine-resistant prolactinoma. tissue_expression_ns hsa-mir-136 Prolactinoma 25064468 Our study is the first to identify a miRNA expression profile associated with bromocriptine-resistant prolactinoma. tissue_expression_ns hsa-mir-142 Prolactinoma 25064468 Our study is the first to identify a miRNA expression profile associated with bromocriptine-resistant prolactinoma. tissue_expression_ns hsa-mir-144 Prolactinoma 25064468 Our study is the first to identify a miRNA expression profile associated with bromocriptine-resistant prolactinoma. tissue_expression_ns hsa-mir-17 Prolactinoma 25064468 Our study is the first to identify a miRNA expression profile associated with bromocriptine-resistant prolactinoma. tissue_expression_ns hsa-mir-22 Prolactinoma 25064468 Our study is the first to identify a miRNA expression profile associated with bromocriptine-resistant prolactinoma. tissue_expression_ns hsa-mir-30a Prolactinoma 25064468 Our study is the first to identify a miRNA expression profile associated with bromocriptine-resistant prolactinoma. tissue_expression_ns hsa-mir-382 Prolactinoma 25064468 Our study is the first to identify a miRNA expression profile associated with bromocriptine-resistant prolactinoma. tissue_expression_ns hsa-mir-451 Prolactinoma 25064468 Our study is the first to identify a miRNA expression profile associated with bromocriptine-resistant prolactinoma. tissue_expression_ns hsa-mir-486 Prolactinoma 25064468 Our study is the first to identify a miRNA expression profile associated with bromocriptine-resistant prolactinoma. tissue_expression_ns hsa-mir-92a Prolactinoma 25064468 Our study is the first to identify a miRNA expression profile associated with bromocriptine-resistant prolactinoma. tissue_expression_ns Hsa-mir-93 Prolactinoma 25064468 Our study is the first to identify a miRNA expression profile associated with bromocriptine-resistant prolactinoma. tissue_expression_ns hsa-mir-18a Acute Respiratory Distress Syndrome 25070658 "miR-26a, miR-346, miR-135b, miR-30a/b, miR-344, and miR-18a targeted multiple altered mRNAs." tissue_expression_ns hsa-mir-133b Neoplasms [unspecific] 25075017 Prognostic microRNA expression signature from examination of colorectal primary and metastatic tumors. tissue_expression_ns hsa-mir-210 Neoplasms [unspecific] 25075017 Prognostic microRNA expression signature from examination of colorectal primary and metastatic tumors. tissue_expression_ns hsa-mir-221 Colon Neoplasms 25075256 "Five miRNAs (miR-203-3p, miR-221-3p, miR-342-3p, miR-491-5p and miR-503-5p) were dysregulated in colon cancer tissue (P < 0.05)." tissue_expression_ns hsa-mir-150 Digeorge Syndrome 25084529 Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome. tissue_expression_ns hsa-mir-185 Digeorge Syndrome 25084529 Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome. tissue_expression_ns hsa-mir-194 Digeorge Syndrome 25084529 Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome. tissue_expression_ns hsa-mir-155 Hypertension 25087597 "In addition, exercise training in SHR increased levels of microRNA-27a (targeting ACE) and microRNA-155 (targeting AT1R) and decreased levels of microRNA-143 (targeting ACE2) in the aortas." tissue_expression_ns hsa-mir-1246 Pancreatic Neoplasms 25117811 "miR-1246 expression was associated with chemoresistance and CSC-like properties via CCNG2, and could predict worse prognosis in pancreatic cancer patients." tissue_expression_ns hsa-mir-378 "Carcinoma, Renal Cell, Clear-Cell" 25119741 "The tumors of patients with ccRCC had lower expression of miR-126 and miR-378 during the early stages of disease (T1), but higher expression of these miRNAs during the later stages of disease (T2/T3)." tissue_expression_ns hsa-mir-126 Lung Neoplasms 25124149 Expression of microRNA miR-126 and miR-200c is associated with prognosis in patients with non-small cell lung cancer. tissue_expression_ns hsa-mir-200c Lung Neoplasms 25124150 Expression of microRNA miR-126 and miR-201c is associated with prognosis in patients with non-small cell lung cancer. tissue_expression_ns hsa-mir-17 Lymphoproliferative Disorders 25130212 "Unsupervised nonhierarchical clustering of the viral and cellular microRNAome distinguished non-EBV-associated from EBV-associated samples and identified a separate group of EBV-associated pCNS PTLD that displayed reduced levels of B cell lymphoma associated oncomiRs such as hsa-miR-155, -21, -221 and the hsa-miR-17-92 cluster." tissue_expression_ns hsa-mir-181b Male Infertility 25141839 "The expression of three out of five selected miRNAs, including miR-34a, miR-181b and miR-122a, showed some degrees of changes following exposure to oxidative stress." tissue_expression_ns hsa-mir-133a Hypertrophy 25147795 "Fifty-seven miRNAs were expressed differentially between transgenic and littermate controls, of which most abundant miRNAs, miR-133a and 378a, were significantly differentially expressed." tissue_expression_ns hsa-mir-21 "Carcinoma, Hepatocellular" 25150373 The results of the present study suggested miR-21 expression level could be a novel potential biomarker for HCC prognosis. tissue_expression_ns hsa-mir-155 Breast Neoplasms 25157366 MiR-155 detection might have a diagnostic value in breast cancer patients. It might be used as an auxiliary biomarker for different clinicopathological breast cancer. tissue_expression_ns hsa-mir-31 Heart Transplant Rejection 25176944 "We identified seven miRNAs that were differentially expressed between normal and rejecting heart allografts: miR-10a, miR-21, miR-31, miR-92a, miR-142-3p miR-155, and miR-451" tissue_expression_ns hsa-mir-106b "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 25189575 "Guo investigated regulation and expression of three miRNAs; miR-21, miR-106b and miR-375. The paper reported these miRNAs as potential biomarkers for laryngeal squamous cell carcinoma diagnosis." tissue_expression_ns hsa-mir-204 Colorectal Carcinoma 25209181 miR-204-5p expression in colorectal cancer: an autophagy-associated gene. tissue_expression_ns hsa-mir-146a Asthma 25217662 MicroRNA-146a and microRNA-146b expression and anti-inflammatory function in human airway smooth muscle. tissue_expression_ns hsa-mir-146b Asthma 25217662 MicroRNA-146a and microRNA-146b expression and anti-inflammatory function in human airway smooth muscle. tissue_expression_ns hsa-mir-21 Inflammatory Bowel Diseases 25222661 "MiRNAs are differentially expressed in both human IBD and murine colitis, with overlap of several IBD-associated miRNAs. The demonstration that miR-21-/- deletion exacerbated CD4+ T-cell-mediated models of colitis provide further evidence that miRNAs play significant roles in the pathogenesis of IBD." tissue_expression_ns hsa-mir-135b "Adenocarcinoma, Cervical" 25230213 "MiR-135b, miR-192, and miR-194 are altered in uterine cervical ACA, and miR-363-3p is an independent favorable prognostic factor in ACA. These miRNAs could be of value as biomarkers for the diagnosis and prognosis of ACA." tissue_expression_ns hsa-mir-192 "Adenocarcinoma, Cervical" 25230213 "MiR-135b, miR-192, and miR-194 are altered in uterine cervical ACA, and miR-363-3p is an independent favorable prognostic factor in ACA. These miRNAs could be of value as biomarkers for the diagnosis and prognosis of ACA." tissue_expression_ns hsa-mir-194 "Adenocarcinoma, Cervical" 25230213 "MiR-135b, miR-192, and miR-194 are altered in uterine cervical ACA, and miR-363-3p is an independent favorable prognostic factor in ACA. These miRNAs could be of value as biomarkers for the diagnosis and prognosis of ACA." tissue_expression_ns hsa-mir-31 Colorectal Carcinoma 25232271 MicroRNA-31 expression in colorectal serrated pathway progression. tissue_expression_ns hsa-mir-23b "Carcinoma, Adenoid Cystic" 25240490 "9 microRNAs were downexpressed in sACC cases and overexpressed in bACC tissues (let-7e, miR-23b, miR-27b, miR-193b, miR-320a, miR-320c, miR-768-5p, miR-1280 and miR-1826) relative to their controls." tissue_expression_ns hsa-mir-155 Lymphoma 25265435 Differential expression of miR-155 and miR-21 in tumor and stroma cells in diffuse large B-cell lymphoma. tissue_expression_ns hsa-mir-21 Lymphoma 25265435 Differential expression of miR-155 and miR-21 in tumor and stroma cells in diffuse large B-cell lymphoma. tissue_expression_ns hsa-mir-10a "Carcinoma, Laryngeal" 25266939 MicroRNA-10a-5p and microRNA-34c-5p in laryngeal epithelial premalignant lesions:differential expression and clinicopathological correlation. tissue_expression_ns hsa-mir-34c "Carcinoma, Laryngeal" 25266939 MicroRNA-10a-5p and microRNA-34c-5p in laryngeal epithelial premalignant lesions:differential expression and clinicopathological correlation. tissue_expression_ns hsa-mir-215 Breast Neoplasms 25270284 Aberrant miR-215 expression is associated with clinical outcome in breast cancer patients. tissue_expression_ns hsa-mir-208 Heart Failure 25287062 "miR-208, which was progressively downregulated as RV failure progressed" tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 25292032 "Our findings suggest that miR-21 has a potential diagnostic value for CRC with a moderate level of overall diagnostic accuracy. Hence, it could be used as auxiliary means for the initial screening of CRC and avoid unnecessary colonoscopy, which is an invasive and expensive procedure." tissue_expression_ns hsa-mir-34a Neuroblastoma 25292042 "Hsa-miR-34a, for example, targets gene MYC, which regulates hsa-miR-34a in turn." tissue_expression_ns hsa-mir-143 Intracranial Aneurysm 25300531 "As compared to normal arteries, we identified 157 microRNAs that were differentially expressed in the aneurysmal tissue (Pâ€?â€?.05 and fold change ≥â€?), including 72 upregulated and 85 downregulated." tissue_expression_ns hsa-mir-23a Osteosarcoma 25322765 We identified miR-23a as a tumor suppressor in osteosarcoma. Our data clarify the mechanism of osteosarcoma progression and demonstrated the potential for exploiting miR-23a as a diagnostic marker for osteosarcoma. tissue_expression_ns hsa-mir-335 "Squamous Cell Carcinoma, Esophageal" 25337272 "miR-335 expression isan independent prognostic factor for patients with esophageal cancer, which might be a potential valuable biomarker for ESCC." tissue_expression_ns hsa-mir-151 Breast Neoplasms 25339470 "Specific differentially expressed miRNAs of the three subtypes were identified, including hsa-miR-99a and hsa-miR-151-3p for DCIS breast cancer, hsa-miR-145 and hsa-miR-210 for invasive breast cancer, and has-miR-205 and has-miR-361-5p metastatic breast cancer." tissue_expression_ns hsa-mir-224 Hepatitis C Virus Infection 25386083 "Differences in miRNA expression were observed between CHC and steatotic CHC, CHC and steatotic liver, but not between steatotic CHC and steatotic liver of metabolic origin." tissue_expression_ns hsa-mir-33a Hepatitis C Virus Infection 25386083 "Differences in miRNA expression were observed between CHC and steatotic CHC, CHC and steatotic liver, but not between steatotic CHC and steatotic liver of metabolic origin." tissue_expression_ns hsa-mir-1246 Pancreatic Neoplasms 25388097 "the concomitant evaluation of PaCIC and PaCa-related miRNA marker panels awaits retrospective analyses of larger cohorts, as it should allow for a highly sensitive, minimally-invasive PaCa diagnostics." tissue_expression_ns hsa-mir-3976 Pancreatic Neoplasms 25388097 "the concomitant evaluation of PaCIC and PaCa-related miRNA marker panels awaits retrospective analyses of larger cohorts, as it should allow for a highly sensitive, minimally-invasive PaCa diagnostics." tissue_expression_ns hsa-mir-4306 Pancreatic Neoplasms 25388097 "the concomitant evaluation of PaCIC and PaCa-related miRNA marker panels awaits retrospective analyses of larger cohorts, as it should allow for a highly sensitive, minimally-invasive PaCa diagnostics." tissue_expression_ns hsa-mir-4644 Pancreatic Neoplasms 25388097 "the concomitant evaluation of PaCIC and PaCa-related miRNA marker panels awaits retrospective analyses of larger cohorts, as it should allow for a highly sensitive, minimally-invasive PaCa diagnostics." tissue_expression_ns hsa-mir-152 Breast Neoplasms 25393370 "For the first time, a different microRNA expression pattern in male and female fBC has been shown. Moreover, the importance of RASSF1A pathway in male fBC carcinogenesis has been confirmed, highlighting a possible role for miR-152 and miR-497 in controlling MAPK and Hippo signalling pathways, regulated by RASSF1A." tissue_expression_ns hsa-mir-497 Breast Neoplasms 25393370 "For the first time, a different microRNA expression pattern in male and female fBC has been shown. Moreover, the importance of RASSF1A pathway in male fBC carcinogenesis has been confirmed, highlighting a possible role for miR-152 and miR-497 in controlling MAPK and Hippo signalling pathways, regulated by RASSF1A." tissue_expression_ns hsa-mir-105 Glioma 25415048 "miRNA expression patterns in the malignant progression of gliomas and a novel prognostic classifier, the five-miRNA signature, serve as a prognostic marker for patient risk stratification in anaplastic gliomas, Secondary and Proneural glioblastomas." tissue_expression_ns hsa-mir-196a Glioma 25415048 "miRNA expression patterns in the malignant progression of gliomas and a novel prognostic classifier, the five-miRNA signature, serve as a prognostic marker for patient risk stratification in anaplastic gliomas, Secondary and Proneural glioblastomas." tissue_expression_ns hsa-mir-296 Glioma 25415048 "miRNA expression patterns in the malignant progression of gliomas and a novel prognostic classifier, the five-miRNA signature, serve as a prognostic marker for patient risk stratification in anaplastic gliomas, Secondary and Proneural glioblastomas." tissue_expression_ns hsa-mir-584 Glioma 25415048 "miRNA expression patterns in the malignant progression of gliomas and a novel prognostic classifier, the five-miRNA signature, serve as a prognostic marker for patient risk stratification in anaplastic gliomas, Secondary and Proneural glioblastomas." tissue_expression_ns hsa-mir-767 Glioma 25415048 "miRNA expression patterns in the malignant progression of gliomas and a novel prognostic classifier, the five-miRNA signature, serve as a prognostic marker for patient risk stratification in anaplastic gliomas, Secondary and Proneural glioblastomas." tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 25421755 "miR-21 expression may be a valuable biomarker for prediction of poor prognosis in CRC patients with Dukes' stage B, C and D." tissue_expression_ns hsa-mir-125b "Carcinoma, Colon" 25421775 "miR-145 and other 16 miRNAs may be used as diagnostic molecular markers of colon cancer, and miR100, miR125a-5p, miR125b, miR145 and miR145* may become the molecular markers of colon cancer lymph node metastasis." tissue_expression_ns hsa-mir-145 "Carcinoma, Colon" 25421775 "miR-145 and other 16 miRNAs may be used as diagnostic molecular markers of colon cancer, and miR100, miR125a-5p, miR125b, miR145 and miR146* may become the molecular markers of colon cancer lymph node metastasis." tissue_expression_ns hsa-mir-192 "Adenocarcinoma, Gastric-Esophageal Junction" 25429911 "Comprehensive miRNA profiling showed a differential microRNA expression pattern depending on the histomorphologic regression in the multimodality therapy of locally advanced adenocarcinomas of the gastroesophageal junction. Moreover, using single RT-PCR analyses a prognostic impact of miR-222 and miR-302c was detected." tissue_expression_ns hsa-mir-21 "Adenocarcinoma, Gastric-Esophageal Junction" 25429911 "Comprehensive miRNA profiling showed a differential microRNA expression pattern depending on the histomorphologic regression in the multimodality therapy of locally advanced adenocarcinomas of the gastroesophageal junction. Moreover, using single RT-PCR analyses a prognostic impact of miR-222 and miR-302c was detected." tissue_expression_ns hsa-mir-222 "Adenocarcinoma, Gastric-Esophageal Junction" 25429911 "Comprehensive miRNA profiling showed a differential microRNA expression pattern depending on the histomorphologic regression in the multimodality therapy of locally advanced adenocarcinomas of the gastroesophageal junction. Moreover, using single RT-PCR analyses a prognostic impact of miR-222 and miR-302c was detected." tissue_expression_ns hsa-mir-302c "Adenocarcinoma, Gastric-Esophageal Junction" 25429911 "Comprehensive miRNA profiling showed a differential microRNA expression pattern depending on the histomorphologic regression in the multimodality therapy of locally advanced adenocarcinomas of the gastroesophageal junction. Moreover, using single RT-PCR analyses a prognostic impact of miR-222 and miR-302c was detected." tissue_expression_ns hsa-mir-381 "Adenocarcinoma, Gastric-Esophageal Junction" 25429911 "Comprehensive miRNA profiling showed a differential microRNA expression pattern depending on the histomorphologic regression in the multimodality therapy of locally advanced adenocarcinomas of the gastroesophageal junction. Moreover, using single RT-PCR analyses a prognostic impact of miR-222 and miR-302c was detected." tissue_expression_ns hsa-mir-549 "Adenocarcinoma, Gastric-Esophageal Junction" 25429911 "Comprehensive miRNA profiling showed a differential microRNA expression pattern depending on the histomorphologic regression in the multimodality therapy of locally advanced adenocarcinomas of the gastroesophageal junction. Moreover, using single RT-PCR analyses a prognostic impact of miR-222 and miR-302c was detected." tissue_expression_ns hsa-let-7i Ovarian Disease 25451316 "let-7i-5p, miR-122,miR-152-5p and miR-25-3p could act as diagnostic biomarkers in ovarian cancer." tissue_expression_ns hsa-mir-122 Ovarian Disease 25451316 "let-7i-5p, miR-122,miR-152-5p and miR-25-3p could act as diagnostic biomarkers in ovarian cancer." tissue_expression_ns hsa-mir-152 Ovarian Disease 25451316 "let-7i-5p, miR-122,miR-152-5p and miR-25-3p could act as diagnostic biomarkers in ovarian cancer." tissue_expression_ns hsa-mir-25 Ovarian Disease 25451316 "let-7i-5p, miR-122,miR-152-5p and miR-25-3p could act as diagnostic biomarkers in ovarian cancer." tissue_expression_ns hsa-mir-34 Neoplasms [unspecific] 25452192 miR-34 family members could be expected to become potential diagnostic and prognostic biomarkers in some types of human cancers. Further well-designed and larger sample studies are surely warranted to identify the role of the miR-34 family in the occurrence and development of tumors. tissue_expression_ns hsa-mir-21 Glioma 25452796 "Among the six identified differentially expressed miRNAs, hsa-miR-21 and hsa-miR-612 have been previously reported to be associated with glioma." tissue_expression_ns hsa-mir-103a Mesothelioma 25469901 the use of biomarkers of different molecular classes might be a reasonable approach to assemble a biomarker panel. tissue_expression_ns hsa-mir-184 "Squamous Cell Carcinoma, Oral" 25482863 "Our results corroborate the previous findings on the overexpression of mir-21 and downregulation of miR-138 in OSCC. As the expression of miR-184 is controversial in tongue/oral cancer, the downregulation may be specific to tumor anatomical localization. On the other hand, to the best of our knowledge, this is the first report to show the association of miR-155 with tobacco chewing and the downregulation of miR-125b-2* in OSCC. Computational predictions suggest that miR-125b-2* may have a role in alternative splicing." tissue_expression_ns hsa-let-7a Multiple Sclerosis 25487315 some miRNA subsets may be potential biomarkers for MS activity. tissue_expression_ns hsa-mir-648a Multiple Sclerosis 25487315 some miRNA subsets may be potential biomarkers for MS activity. tissue_expression_ns hsa-mir-92a Multiple Sclerosis 25487315 some miRNA subsets may be potential biomarkers for MS activity. tissue_expression_ns hsa-mir-106a Preeclampsia 25499681 facilitate further investigation of aberrant expression of miRNAs in the pathology of preeclampsia. tissue_expression_ns hsa-mir-363 Preeclampsia 25499681 facilitate further investigation of aberrant expression of miRNAs in the pathology of preeclampsia. tissue_expression_ns hsa-mir-126 Osteosarcoma 25510179 expression of miR-126 increased the sensitivity of osteosarcoma cells to EGCG through induction of apoptosis. tissue_expression_ns hsa-mir-96 Bladder Neoplasms 25511320 Urinary miRNA-96 is a good noninvasive diagnostic biomarker for bladder cancer. tissue_expression_ns hsa-mir-101 "Squamous Cell Carcinoma, Esophageal" 25538231 A significant negative correlation exists between miR-101 or miR-217 and MALAT1 in 42 pairs of ESCC tissue samples and adjacent normal tissues. Mice xenograft data also support the tumor suppressor role of both miRNAs in ESCCs. tissue_expression_ns hsa-mir-217 "Squamous Cell Carcinoma, Esophageal" 25538231 A significant negative correlation exists between miR-101 or miR-217 and MALAT1 in 42 pairs of ESCC tissue samples and adjacent normal tissues. Mice xenograft data also support the tumor suppressor role of both miRNAs in ESCCs. tissue_expression_ns hsa-mir-15a Breast Neoplasms 25550542 MiR-15a expression levels could be a promising biological and prognostic marker for overall survival especially in triple-negative BC cases. tissue_expression_ns hsa-mir-155 Human Papilloma Virus Infection 25550598 Evaluation of miRNA expression might be helpful to distinguish different cervical lesions and might be able to help in the prediction of HPV infection outcome. epithelial cell adhesion molecule tissue_expression_ns hsa-mir-196a Human Papilloma Virus Infection 25550598 Evaluation of miRNA expression might be helpful to distinguish different cervical lesions and might be able to help in the prediction of HPV infection outcome. epithelial cell adhesion molecule tissue_expression_ns hsa-mir-203 Human Papilloma Virus Infection 25550598 Evaluation of miRNA expression might be helpful to distinguish different cervical lesions and might be able to help in the prediction of HPV infection outcome. epithelial cell adhesion molecule tissue_expression_ns hsa-mir-27a Human Papilloma Virus Infection 25550598 Evaluation of miRNA expression might be helpful to distinguish different cervical lesions and might be able to help in the prediction of HPV infection outcome. epithelial cell adhesion molecule tissue_expression_ns hsa-mir-34a Human Papilloma Virus Infection 25550598 Evaluation of miRNA expression might be helpful to distinguish different cervical lesions and might be able to help in the prediction of HPV infection outcome. epithelial cell adhesion molecule tissue_expression_ns hsa-mir-132 Inflammation 25564423 We assessed miRNA and mRNA expression in lung infiltrating mononuclear cells following exposure to SEB and found 89 miRNA that were dysregulated (>2-fold) compared with vehicle controls. tissue_expression_ns hsa-mir-125a Colorectal Adenoma 25586944 "several miRNAs were abnormally expressed in colorectal lesions, identified new deregulated miRs, and showed that several miRNAs could mark the transition from NOR to CRA, thereby marking progression from the early steps of cancer." tissue_expression_ns hsa-mir-145 Colorectal Adenoma 25586944 "several miRNAs were abnormally expressed in colorectal lesions, identified new deregulated miRs, and showed that several miRNAs could mark the transition from NOR to CRA, thereby marking progression from the early steps of cancer." tissue_expression_ns hsa-mir-15b Colorectal Adenoma 25586944 "several miRNAs were abnormally expressed in colorectal lesions, identified new deregulated miRs, and showed that several miRNAs could mark the transition from NOR to CRA, thereby marking progression from the early steps of cancer." tissue_expression_ns hsa-mir-16 Colorectal Adenoma 25586944 "several miRNAs were abnormally expressed in colorectal lesions, identified new deregulated miRs, and showed that several miRNAs could mark the transition from NOR to CRA, thereby marking progression from the early steps of cancer." tissue_expression_ns hsa-mir-21 Colorectal Adenoma 25586944 "several miRNAs were abnormally expressed in colorectal lesions, identified new deregulated miRs, and showed that several miRNAs could mark the transition from NOR to CRA, thereby marking progression from the early steps of cancer." tissue_expression_ns hsa-mir-24 Colorectal Adenoma 25586944 "several miRNAs were abnormally expressed in colorectal lesions, identified new deregulated miRs, and showed that several miRNAs could mark the transition from NOR to CRA, thereby marking progression from the early steps of cancer." tissue_expression_ns hsa-mir-320 Colorectal Adenoma 25586944 "several miRNAs were abnormally expressed in colorectal lesions, identified new deregulated miRs, and showed that several miRNAs could mark the transition from NOR to CRA, thereby marking progression from the early steps of cancer." tissue_expression_ns hsa-mir-320b Colorectal Adenoma 25586944 "several miRNAs were abnormally expressed in colorectal lesions, identified new deregulated miRs, and showed that several miRNAs could mark the transition from NOR to CRA, thereby marking progression from the early steps of cancer." tissue_expression_ns hsa-mir-378 Colorectal Adenoma 25586944 "several miRNAs were abnormally expressed in colorectal lesions, identified new deregulated miRs, and showed that several miRNAs could mark the transition from NOR to CRA, thereby marking progression from the early steps of cancer." tissue_expression_ns hsa-mir-126 Colorectal Carcinoma 25592646 "The intra-tumoural expression of EGFL7 in early stages of CRC may influence the risk of post-surgical recurrence. Differential expression of miRNA-126 seems more pronounced in disseminated disease, which supports its role as a regulator in the metastatic process." tissue_expression_ns hsa-mir-107 Glioma 25596705 expression level of miR-107 may be a novel and valuable prognostic factor in glioma. tissue_expression_ns hsa-mir-26a Colorectal Carcinoma 25611389 Genome-wide mRNA and miRNA expression profiling reveal multiple regulatory networks in colorectal cancer. tissue_expression_ns hsa-mir-375 "Squamous Cell Carcinoma, Tongue" 25633534 "miR-375 inhibits the cell growth, and its expression is correlated with clinical outcomes in TSCC." tissue_expression_ns hsa-mir-93 "Carcinoma, Hepatocellular" 25633810 "miR-93 stimulated cell proliferation,migration, and invasion through the oncogenic c-Met/PI3K/Akt pathway and also inhibited apoptosis by directly inhibiting PTEN and CDKN1A expression in human HCC." tissue_expression_ns hsa-mir-146a Psoriasis 25662483 "In the mouse model of Aldara-induced skin inflammation, the level of miR-146a increased" tissue_expression_ns hsa-mir-1203 "Small Cell Carcinoma, Esophageal" 25667451 The expression profiles of microRNAs in tumors may represent a novel predictor for postoperative outcomes in patients with SCCE. tissue_expression_ns hsa-mir-1249 "Small Cell Carcinoma, Esophageal" 25667451 The expression profiles of microRNAs in tumors may represent a novel predictor for postoperative outcomes in patients with SCCE. tissue_expression_ns hsa-mir-3619 "Small Cell Carcinoma, Esophageal" 25667451 The expression profiles of microRNAs in tumors may represent a novel predictor for postoperative outcomes in patients with SCCE. tissue_expression_ns hsa-mir-4419b "Small Cell Carcinoma, Esophageal" 25667451 The expression profiles of microRNAs in tumors may represent a novel predictor for postoperative outcomes in patients with SCCE. tissue_expression_ns hsa-mir-4648 "Small Cell Carcinoma, Esophageal" 25667451 The expression profiles of microRNAs in tumors may represent a novel predictor for postoperative outcomes in patients with SCCE. tissue_expression_ns hsa-mir-4664 "Small Cell Carcinoma, Esophageal" 25667451 The expression profiles of microRNAs in tumors may represent a novel predictor for postoperative outcomes in patients with SCCE. tissue_expression_ns hsa-mir-143 "Carcinoma, Esophageal" 25667498 Alterations of miRNA expression in ESCC can be correlated with the presence of common risk factors. The altered expression of certain miRNAs could be used as novel molecular markers of esophageal carcinoma. tissue_expression_ns hsa-mir-203 "Carcinoma, Esophageal" 25667498 Alterations of miRNA expression in ESCC can be correlated with the presence of common risk factors. The altered expression of certain miRNAs could be used as novel molecular markers of esophageal carcinoma. tissue_expression_ns hsa-mir-205 "Carcinoma, Esophageal" 25667498 Alterations of miRNA expression in ESCC can be correlated with the presence of common risk factors. The altered expression of certain miRNAs could be used as novel molecular markers of esophageal carcinoma. tissue_expression_ns hsa-mir-21 "Carcinoma, Esophageal" 25667498 Alterations of miRNA expression in ESCC can be correlated with the presence of common risk factors. The altered expression of certain miRNAs could be used as novel molecular markers of esophageal carcinoma. tissue_expression_ns hsa-mir-221 "Carcinoma, Esophageal" 25667498 Alterations of miRNA expression in ESCC can be correlated with the presence of common risk factors. The altered expression of certain miRNAs could be used as novel molecular markers of esophageal carcinoma. tissue_expression_ns hsa-mir-23a Gastric Neoplasms 25674252 These results suggest that the dysregulation of miR-23a and miR-23b may be implicated in the progression of human GC. Combined expression of miR-23a and miR-23b appears to be a valuable marker for prognosis of this disease. tissue_expression_ns hsa-mir-23b Gastric Neoplasms 25674252 These results suggest that the dysregulation of miR-23a and miR-23b may be implicated in the progression of human GC. Combined expression of miR-23a and miR-23b appears to be a valuable marker for prognosis of this disease. tissue_expression_ns hsa-mir-19b Parkinson Disease 25675938 Our findings indicate that dysregulation of the microRNA miR-19b occurs in the prodromal stage of synucleinopathies. tissue_expression_ns hsa-mir-29a Parkinson Disease 25675938 Our findings indicate that dysregulation of the microRNA miR-19b occurs in the prodromal stage of synucleinopathies. tissue_expression_ns hsa-mir-29c Parkinson Disease 25675938 Our findings indicate that dysregulation of the microRNA miR-19b occurs in the prodromal stage of synucleinopathies. tissue_expression_ns hsa-mir-1207 Gastric Neoplasms 25688358 "Multivariate analysis showed that stromal reaction type, lymphovascular invasion, pathological T category and TNM stage, and expression of miR-1207-5p were independent risk factors of LNM. MiR-1207-5p could serve as a useful biomarker in the prediction of LNM in gastric cancer." tissue_expression_ns hsa-mir-330 "Muscular Dystrophy, Facioscapulohumeral" 25692472 "This work provides new candidate mechanisms potentially involved in the onset of FSHD pathology. Whether these FSHD specific miRNAs cause deregulations during fetal development, or protect against the appearance of the FSHD phenotype until the second decade of life still needs to be investigated." tissue_expression_ns hsa-mir-331 "Muscular Dystrophy, Facioscapulohumeral" 25692472 "This work provides new candidate mechanisms potentially involved in the onset of FSHD pathology. Whether these FSHD specific miRNAs cause deregulations during fetal development, or protect against the appearance of the FSHD phenotype until the second decade of life still needs to be investigated." tissue_expression_ns hsa-mir-34a "Muscular Dystrophy, Facioscapulohumeral" 25692472 "This work provides new candidate mechanisms potentially involved in the onset of FSHD pathology. Whether these FSHD specific miRNAs cause deregulations during fetal development, or protect against the appearance of the FSHD phenotype until the second decade of life still needs to be investigated." tissue_expression_ns hsa-mir-380 "Muscular Dystrophy, Facioscapulohumeral" 25692472 "This work provides new candidate mechanisms potentially involved in the onset of FSHD pathology. Whether these FSHD specific miRNAs cause deregulations during fetal development, or protect against the appearance of the FSHD phenotype until the second decade of life still needs to be investigated." tissue_expression_ns hsa-mir-516b "Muscular Dystrophy, Facioscapulohumeral" 25692472 "This work provides new candidate mechanisms potentially involved in the onset of FSHD pathology. Whether these FSHD specific miRNAs cause deregulations during fetal development, or protect against the appearance of the FSHD phenotype until the second decade of life still needs to be investigated." tissue_expression_ns hsa-mir-517 "Muscular Dystrophy, Facioscapulohumeral" 25692472 "This work provides new candidate mechanisms potentially involved in the onset of FSHD pathology. Whether these FSHD specific miRNAs cause deregulations during fetal development, or protect against the appearance of the FSHD phenotype until the second decade of life still needs to be investigated." tissue_expression_ns hsa-mir-582 "Muscular Dystrophy, Facioscapulohumeral" 25692472 "This work provides new candidate mechanisms potentially involved in the onset of FSHD pathology. Whether these FSHD specific miRNAs cause deregulations during fetal development, or protect against the appearance of the FSHD phenotype until the second decade of life still needs to be investigated." tissue_expression_ns hsa-mir-625 "Muscular Dystrophy, Facioscapulohumeral" 25692472 "This work provides new candidate mechanisms potentially involved in the onset of FSHD pathology. Whether these FSHD specific miRNAs cause deregulations during fetal development, or protect against the appearance of the FSHD phenotype until the second decade of life still needs to be investigated." tissue_expression_ns hsa-mir-155 Mycosis Fungoides 25698383 These results by identifying a number of differentially expressed microRNAs add further insight into the molecular pathogenesis of folliculotropic MF and large cell transformation of MF. tissue_expression_ns hsa-mir-181b Mycosis Fungoides 25698383 These results by identifying a number of differentially expressed microRNAs add further insight into the molecular pathogenesis of folliculotropic MF and large cell transformation of MF. tissue_expression_ns hsa-mir-223 Mycosis Fungoides 25698383 These results by identifying a number of differentially expressed microRNAs add further insight into the molecular pathogenesis of folliculotropic MF and large cell transformation of MF. tissue_expression_ns hsa-mir-326 Mycosis Fungoides 25698383 These results by identifying a number of differentially expressed microRNAs add further insight into the molecular pathogenesis of folliculotropic MF and large cell transformation of MF. tissue_expression_ns hsa-mir-206 Muscle Diseases [unspecific] 25703017 "Thirty-six miRNAs were differentially expressed between prenatal and postnatal stages of muscle development including several myomiRs (miR-1, miR-206 and let-7 families)." tissue_expression_ns hsa-mir-183 Prostate Neoplasms 25720086 Urinary miR-183 and miR-205 do not surpass PCA3 in urine as predictive markers for prostate biopsy outcome despite their highly dysregulated expression in prostate cancer tissue. tissue_expression_ns hsa-mir-205 Prostate Neoplasms 25720086 Urinary miR-183 and miR-205 do not surpass PCA3 in urine as predictive markers for prostate biopsy outcome despite their highly dysregulated expression in prostate cancer tissue. tissue_expression_ns hsa-let-7a "Carcinoma, Thyroid, Papillary" 25720323 This comprehensive study complements the existing knowledge about deregulated microRNAs in the development of well-differentiated thyroid cancer and identifies novel markers associated with recurrence-free survival. tissue_expression_ns hsa-mir-1179 "Carcinoma, Thyroid, Papillary" 25720323 This comprehensive study complements the existing knowledge about deregulated microRNAs in the development of well-differentiated thyroid cancer and identifies novel markers associated with recurrence-free survival. tissue_expression_ns hsa-mir-146b "Carcinoma, Thyroid, Papillary" 25720323 This comprehensive study complements the existing knowledge about deregulated microRNAs in the development of well-differentiated thyroid cancer and identifies novel markers associated with recurrence-free survival. tissue_expression_ns hsa-mir-192 "Carcinoma, Thyroid, Papillary" 25720323 This comprehensive study complements the existing knowledge about deregulated microRNAs in the development of well-differentiated thyroid cancer and identifies novel markers associated with recurrence-free survival. tissue_expression_ns hsa-mir-204 "Carcinoma, Thyroid, Papillary" 25720323 This comprehensive study complements the existing knowledge about deregulated microRNAs in the development of well-differentiated thyroid cancer and identifies novel markers associated with recurrence-free survival. tissue_expression_ns hsa-mir-221 "Carcinoma, Thyroid, Papillary" 25720323 This comprehensive study complements the existing knowledge about deregulated microRNAs in the development of well-differentiated thyroid cancer and identifies novel markers associated with recurrence-free survival. tissue_expression_ns hsa-mir-222 "Carcinoma, Thyroid, Papillary" 25720323 This comprehensive study complements the existing knowledge about deregulated microRNAs in the development of well-differentiated thyroid cancer and identifies novel markers associated with recurrence-free survival. tissue_expression_ns hsa-mir-7 "Carcinoma, Thyroid, Papillary" 25720323 This comprehensive study complements the existing knowledge about deregulated microRNAs in the development of well-differentiated thyroid cancer and identifies novel markers associated with recurrence-free survival. tissue_expression_ns hsa-mir-1914 "Carcinoma, Gastric" 25730011 The miRNA expression patterns in different gastric adenocarcinoma subtypes may help discriminate between signet-ring cell and tubular gland cancer or other gastric cancer subtypes that would otherwise be difficult to identify using routine histological and immunohistochemical analyses. These preliminary data should be verified in further prospective studies. tissue_expression_ns hsa-mir-499 "Carcinoma, Gastric" 25730011 The miRNA expression patterns in different gastric adenocarcinoma subtypes may help discriminate between signet-ring cell and tubular gland cancer or other gastric cancer subtypes that would otherwise be difficult to identify using routine histological and immunohistochemical analyses. These preliminary data should be verified in further prospective studies. tissue_expression_ns hsa-mir-524 "Carcinoma, Gastric" 25730011 The miRNA expression patterns in different gastric adenocarcinoma subtypes may help discriminate between signet-ring cell and tubular gland cancer or other gastric cancer subtypes that would otherwise be difficult to identify using routine histological and immunohistochemical analyses. These preliminary data should be verified in further prospective studies. tissue_expression_ns hsa-mir-628 "Carcinoma, Gastric" 25730011 The miRNA expression patterns in different gastric adenocarcinoma subtypes may help discriminate between signet-ring cell and tubular gland cancer or other gastric cancer subtypes that would otherwise be difficult to identify using routine histological and immunohistochemical analyses. These preliminary data should be verified in further prospective studies. tissue_expression_ns hsa-mir-125a Head And Neck Adenoid Cystic Carcinoma 25750274 Our data showed significantly different expression patterns of mircoRNA in HNACC and HNSCC supporting the theory of tumor-specific expression and giving hints for different clinical behavior. review tissue_expression_ns hsa-mir-199a Head And Neck Adenoid Cystic Carcinoma 25750274 Our data showed significantly different expression patterns of mircoRNA in HNACC and HNSCC supporting the theory of tumor-specific expression and giving hints for different clinical behavior. review tissue_expression_ns hsa-mir-199b Head And Neck Adenoid Cystic Carcinoma 25750274 Our data showed significantly different expression patterns of mircoRNA in HNACC and HNSCC supporting the theory of tumor-specific expression and giving hints for different clinical behavior. review tissue_expression_ns hsa-mir-214 Head And Neck Adenoid Cystic Carcinoma 25750274 Our data showed significantly different expression patterns of mircoRNA in HNACC and HNSCC supporting the theory of tumor-specific expression and giving hints for different clinical behavior. review tissue_expression_ns hsa-mir-574 Head And Neck Adenoid Cystic Carcinoma 25750274 Our data showed significantly different expression patterns of mircoRNA in HNACC and HNSCC supporting the theory of tumor-specific expression and giving hints for different clinical behavior. review tissue_expression_ns hsa-mir-106b "Carcinoma, Colon" 25755775 In situ hybridization analysis of the expression of miR-106b in colonic cancer. tissue_expression_ns hsa-mir-122 Obesity 25769350 "Deregulation of miR-33 and miR-122, as major regulators of lipid metabolism in liver, has been related to obesity and metabolic syndrome." tissue_expression_ns hsa-mir-146b "Carcinoma, Thyroid, Papillary" 25771986 "Since miR-146b-5p was mainly expressed in PTC including FVPTC and was not expressed in most FTC, PDTC, or ATC, it may serve as a useful diagnostic marker for PTC. ISH is a useful method to analyze microRNA expression in formalin-fixed paraffin-embedded thyroid tissues." tissue_expression_ns hsa-mir-21 "Carcinoma, Thyroid, Papillary" 25771986 "Since miR-146b-5p was mainly expressed in PTC including FVPTC and was not expressed in most FTC, PDTC, or ATC, it may serve as a useful diagnostic marker for PTC. ISH is a useful method to analyze microRNA expression in formalin-fixed paraffin-embedded thyroid tissues." tissue_expression_ns hsa-mir-106a Colorectal Carcinoma 25773836 "Our study revealed dysregulation of expression of ten miRNAs in Turkish colon cancer patients. These miRNAs may be used as potential biomarkers for early detection, screening and surveillance of colorectal cancer, with functional effects on tumor cell behavior." tissue_expression_ns hsa-mir-127 Colorectal Carcinoma 25773836 "Our study revealed dysregulation of expression of ten miRNAs in Turkish colon cancer patients. These miRNAs may be used as potential biomarkers for early detection, screening and surveillance of colorectal cancer, with functional effects on tumor cell behavior." tissue_expression_ns hsa-mir-133a Colorectal Carcinoma 25773836 "Our study revealed dysregulation of expression of ten miRNAs in Turkish colon cancer patients. These miRNAs may be used as potential biomarkers for early detection, screening and surveillance of colorectal cancer, with functional effects on tumor cell behavior." tissue_expression_ns hsa-mir-133b Colorectal Carcinoma 25773836 "Our study revealed dysregulation of expression of ten miRNAs in Turkish colon cancer patients. These miRNAs may be used as potential biomarkers for early detection, screening and surveillance of colorectal cancer, with functional effects on tumor cell behavior." tissue_expression_ns hsa-mir-135b Colorectal Carcinoma 25773836 "Our study revealed dysregulation of expression of ten miRNAs in Turkish colon cancer patients. These miRNAs may be used as potential biomarkers for early detection, screening and surveillance of colorectal cancer, with functional effects on tumor cell behavior." tissue_expression_ns hsa-mir-143 Colorectal Carcinoma 25773836 "Our study revealed dysregulation of expression of ten miRNAs in Turkish colon cancer patients. These miRNAs may be used as potential biomarkers for early detection, screening and surveillance of colorectal cancer, with functional effects on tumor cell behavior." tissue_expression_ns hsa-mir-145 Colorectal Carcinoma 25773836 "Our study revealed dysregulation of expression of ten miRNAs in Turkish colon cancer patients. These miRNAs may be used as potential biomarkers for early detection, screening and surveillance of colorectal cancer, with functional effects on tumor cell behavior." tissue_expression_ns hsa-mir-155 Colorectal Carcinoma 25773836 "Our study revealed dysregulation of expression of ten miRNAs in Turkish colon cancer patients. These miRNAs may be used as potential biomarkers for early detection, screening and surveillance of colorectal cancer, with functional effects on tumor cell behavior." tissue_expression_ns hsa-mir-182 Colorectal Carcinoma 25773836 "Our study revealed dysregulation of expression of ten miRNAs in Turkish colon cancer patients. These miRNAs may be used as potential biomarkers for early detection, screening and surveillance of colorectal cancer, with functional effects on tumor cell behavior." tissue_expression_ns hsa-mir-200a Colorectal Carcinoma 25773836 "Our study revealed dysregulation of expression of ten miRNAs in Turkish colon cancer patients. These miRNAs may be used as potential biomarkers for early detection, screening and surveillance of colorectal cancer, with functional effects on tumor cell behavior." tissue_expression_ns hsa-mir-200c Colorectal Carcinoma 25773836 "Our study revealed dysregulation of expression of ten miRNAs in Turkish colon cancer patients. These miRNAs may be used as potential biomarkers for early detection, screening and surveillance of colorectal cancer, with functional effects on tumor cell behavior." tissue_expression_ns hsa-mir-362 Colorectal Carcinoma 25773836 "Our study revealed dysregulation of expression of ten miRNAs in Turkish colon cancer patients. These miRNAs may be used as potential biomarkers for early detection, screening and surveillance of colorectal cancer, with functional effects on tumor cell behavior." tissue_expression_ns hsa-mir-203 "Adenocarcinoma, Esophageal" 25784377 We suggest that miRNA expression profiling expands current knowledge in molecular pathology of Barrett's-based carcinogenesis and enables identification of molecular biomarkers for early detection of BE dysplasia and progression to EAC. tissue_expression_ns hsa-mir-205 "Adenocarcinoma, Esophageal" 25784377 We suggest that miRNA expression profiling expands current knowledge in molecular pathology of Barrett's-based carcinogenesis and enables identification of molecular biomarkers for early detection of BE dysplasia and progression to EAC. tissue_expression_ns hsa-mir-210 "Adenocarcinoma, Esophageal" 25784377 We suggest that miRNA expression profiling expands current knowledge in molecular pathology of Barrett's-based carcinogenesis and enables identification of molecular biomarkers for early detection of BE dysplasia and progression to EAC. tissue_expression_ns hsa-mir-378 "Adenocarcinoma, Esophageal" 25784377 We suggest that miRNA expression profiling expands current knowledge in molecular pathology of Barrett's-based carcinogenesis and enables identification of molecular biomarkers for early detection of BE dysplasia and progression to EAC. tissue_expression_ns hsa-mir-140 Osteoarthritis 25785087 We verified that miR-140 and miR-455 were associated with cartilage development tissue_expression_ns hsa-mir-9 Osteoarthritis 25785087 "miR-9 and miR-98 were involved in the endochondral ossification, suggesting they may be also the key regulators in the process of endochondral ossification." tissue_expression_ns hsa-mir-98 Osteoarthritis 25785087 "miR-9 and miR-98 were involved in the endochondral ossification, suggesting they may be also the key regulators in the process of endochondral ossification." tissue_expression_ns hsa-mir-141 Neoplasms [unspecific] 25789530 miR-141 as a prognostic and diagnostic biomarker in different types of cancer tissue_expression_ns hsa-mir-145 Neoplasms [unspecific] 25792469 "In conclusion, our findings suggest that miR-145 expression is associated with overall survival (OS) in cancer patients and can serve as a promising biomarker for monitoring prognosis." tissue_expression_ns hsa-mir-517a Preeclampsia 25799546 Placental expression of miR-517a/b and miR-517c contributes to trophoblast dysfunction and preeclampsia. tissue_expression_ns hsa-mir-517b Preeclampsia 25799546 Placental expression of miR-517a/b and miR-517c contributes to trophoblast dysfunction and preeclampsia. tissue_expression_ns hsa-mir-517c Preeclampsia 25799546 Placental expression of miR-517a/b and miR-517c contributes to trophoblast dysfunction and preeclampsia. tissue_expression_ns hsa-mir-1 Colorectal Adenocarcinoma 25803870 Identification and validation of potential biomarkers for the detection of dysregulated microRNA by qPCR in patients with colorectal adenocarcinoma. tissue_expression_ns hsa-mir-135b Colorectal Adenocarcinoma 25803870 Identification and validation of potential biomarkers for the detection of dysregulated microRNA by qPCR in patients with colorectal adenocarcinoma. tissue_expression_ns hsa-mir-145 Colorectal Adenocarcinoma 25803870 Identification and validation of potential biomarkers for the detection of dysregulated microRNA by qPCR in patients with colorectal adenocarcinoma. tissue_expression_ns hsa-mir-3195 Colorectal Adenocarcinoma 25803870 Identification and validation of potential biomarkers for the detection of dysregulated microRNA by qPCR in patients with colorectal adenocarcinoma. tissue_expression_ns hsa-mir-429 Colorectal Adenocarcinoma 25803870 Identification and validation of potential biomarkers for the detection of dysregulated microRNA by qPCR in patients with colorectal adenocarcinoma. tissue_expression_ns hsa-mir-4469 Colorectal Adenocarcinoma 25803870 Identification and validation of potential biomarkers for the detection of dysregulated microRNA by qPCR in patients with colorectal adenocarcinoma. tissue_expression_ns hsa-mir-4510 Colorectal Adenocarcinoma 25803870 Identification and validation of potential biomarkers for the detection of dysregulated microRNA by qPCR in patients with colorectal adenocarcinoma. tissue_expression_ns hsa-mir-4770 Colorectal Adenocarcinoma 25803870 Identification and validation of potential biomarkers for the detection of dysregulated microRNA by qPCR in patients with colorectal adenocarcinoma. tissue_expression_ns hsa-mir-549 Colorectal Adenocarcinoma 25803870 Identification and validation of potential biomarkers for the detection of dysregulated microRNA by qPCR in patients with colorectal adenocarcinoma. tissue_expression_ns hsa-mir-552 Colorectal Adenocarcinoma 25803870 Identification and validation of potential biomarkers for the detection of dysregulated microRNA by qPCR in patients with colorectal adenocarcinoma. tissue_expression_ns hsa-mir-96 Colorectal Adenocarcinoma 25803870 Identification and validation of potential biomarkers for the detection of dysregulated microRNA by qPCR in patients with colorectal adenocarcinoma. tissue_expression_ns hsa-mir-99b Colorectal Adenocarcinoma 25803870 Identification and validation of potential biomarkers for the detection of dysregulated microRNA by qPCR in patients with colorectal adenocarcinoma. tissue_expression_ns hsa-mir-211 Medulloepithelioma 25807141 "We report significantly dysregulated miRNAs in intraocular ME tumors, which exhibited abnormal profiles in other cancers as well such as retinoblastoma and glioblastoma. Pathway analysis of all dysregulated miRNAs shared commonalities with other cancer pathways." tissue_expression_ns hsa-mir-509 Medulloepithelioma 25807141 "We report significantly dysregulated miRNAs in intraocular ME tumors, which exhibited abnormal profiles in other cancers as well such as retinoblastoma and glioblastoma. Pathway analysis of all dysregulated miRNAs shared commonalities with other cancer pathways." tissue_expression_ns hsa-mir-1237 Spinal Chordoma 25850393 The data from the current study identified a total of 29 differentially expressed miRNAs in chordoma tissues and reduced miR-1237-3p expression was associated with chordoma invasion and worse recurrence-free survival of the patients. tissue_expression_ns hsa-mir-143 "Carcinoma, Lung, Non-Small-Cell" 25862841 miRNA expression profiling of sputum and BAL fluids represent a potential means to detect early-stage NSCLC. tissue_expression_ns hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 25862841 miRNA expression profiling of sputum and BAL fluids represent a potential means to detect early-stage NSCLC. tissue_expression_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 25862841 miRNA expression profiling of sputum and BAL fluids represent a potential means to detect early-stage NSCLC. tissue_expression_ns hsa-mir-210 "Carcinoma, Lung, Non-Small-Cell" 25862841 miRNA expression profiling of sputum and BAL fluids represent a potential means to detect early-stage NSCLC. tissue_expression_ns hsa-mir-372 "Carcinoma, Lung, Non-Small-Cell" 25862841 miRNA expression profiling of sputum and BAL fluids represent a potential means to detect early-stage NSCLC. tissue_expression_ns hsa-let-7c Non-Traumatic Osteonecrosis 25863178 Our data also manifests that the signaling pathways regulated by these differentially expressed miRNAs might be important in the pathogenesis of non-traumatic ONFH. tissue_expression_ns hsa-let-7i Non-Traumatic Osteonecrosis 25863178 Our data also manifests that the signaling pathways regulated by these differentially expressed miRNAs might be important in the pathogenesis of non-traumatic ONFH. tissue_expression_ns hsa-mir-146b Non-Traumatic Osteonecrosis 25863178 Our data also manifests that the signaling pathways regulated by these differentially expressed miRNAs might be important in the pathogenesis of non-traumatic ONFH. tissue_expression_ns hsa-mir-320e Non-Traumatic Osteonecrosis 25863178 Our data also manifests that the signaling pathways regulated by these differentially expressed miRNAs might be important in the pathogenesis of non-traumatic ONFH. tissue_expression_ns hsa-mir-335 Non-Traumatic Osteonecrosis 25863178 Our data also manifests that the signaling pathways regulated by these differentially expressed miRNAs might be important in the pathogenesis of non-traumatic ONFH. tissue_expression_ns hsa-mir-197 "Carcinoma, Lung, Non-Small-Cell" 25867273 The cost-effective expression analysis of miR-197 could constitute a novel molecular tool for NSCLC management. tissue_expression_ns hsa-let-7d "Carcinoma, Lung, Non-Small-Cell" 25873351 mRNA and microRNA expression profiles of radioresistant NCI-H520 non-small cell lung cancer cells. tissue_expression_ns hsa-mir-127 "Carcinoma, Lung, Non-Small-Cell" 25873351 mRNA and microRNA expression profiles of radioresistant NCI-H520 non-small cell lung cancer cells. tissue_expression_ns hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 25873351 mRNA and microRNA expression profiles of radioresistant NCI-H520 non-small cell lung cancer cells. tissue_expression_ns hsa-mir-103 Intrahepatic Cholangiocarcinoma 25880914 "In this study, a 30-miRNA signature for distinguishing ICC from NIBD, and a 3-miRNA signature for evaluating prognosis of ICC were established, which might be able to serve as biomarkers for prognosis of ICC. Further studies focusing on these miRNAs may shed light on the mechanisms associated with ICC pathogenesis and progression." tissue_expression_ns hsa-mir-146a Intrahepatic Cholangiocarcinoma 25880914 "In this study, a 30-miRNA signature for distinguishing ICC from NIBD, and a 3-miRNA signature for evaluating prognosis of ICC were established, which might be able to serve as biomarkers for prognosis of ICC. Further studies focusing on these miRNAs may shed light on the mechanisms associated with ICC pathogenesis and progression." tissue_expression_ns hsa-mir-216a Intrahepatic Cholangiocarcinoma 25880914 "In this study, a 30-miRNA signature for distinguishing ICC from NIBD, and a 3-miRNA signature for evaluating prognosis of ICC were established, which might be able to serve as biomarkers for prognosis of ICC. Further studies focusing on these miRNAs may shed light on the mechanisms associated with ICC pathogenesis and progression." tissue_expression_ns hsa-mir-216b Intrahepatic Cholangiocarcinoma 25880914 "In this study, a 30-miRNA signature for distinguishing ICC from NIBD, and a 3-miRNA signature for evaluating prognosis of ICC were established, which might be able to serve as biomarkers for prognosis of ICC. Further studies focusing on these miRNAs may shed light on the mechanisms associated with ICC pathogenesis and progression." tissue_expression_ns hsa-mir-217 Intrahepatic Cholangiocarcinoma 25880914 "In this study, a 30-miRNA signature for distinguishing ICC from NIBD, and a 3-miRNA signature for evaluating prognosis of ICC were established, which might be able to serve as biomarkers for prognosis of ICC. Further studies focusing on these miRNAs may shed light on the mechanisms associated with ICC pathogenesis and progression." tissue_expression_ns hsa-mir-338 Intrahepatic Cholangiocarcinoma 25880914 "In this study, a 30-miRNA signature for distinguishing ICC from NIBD, and a 3-miRNA signature for evaluating prognosis of ICC were established, which might be able to serve as biomarkers for prognosis of ICC. Further studies focusing on these miRNAs may shed light on the mechanisms associated with ICC pathogenesis and progression." tissue_expression_ns hsa-mir-513 Intrahepatic Cholangiocarcinoma 25880914 "In this study, a 30-miRNA signature for distinguishing ICC from NIBD, and a 3-miRNA signature for evaluating prognosis of ICC were established, which might be able to serve as biomarkers for prognosis of ICC. Further studies focusing on these miRNAs may shed light on the mechanisms associated with ICC pathogenesis and progression." tissue_expression_ns hsa-mir-652 Intrahepatic Cholangiocarcinoma 25880914 "In this study, a 30-miRNA signature for distinguishing ICC from NIBD, and a 3-miRNA signature for evaluating prognosis of ICC were established, which might be able to serve as biomarkers for prognosis of ICC. Further studies focusing on these miRNAs may shed light on the mechanisms associated with ICC pathogenesis and progression." tissue_expression_ns hsa-mir-675 Intrahepatic Cholangiocarcinoma 25880914 "In this study, a 30-miRNA signature for distinguishing ICC from NIBD, and a 3-miRNA signature for evaluating prognosis of ICC were established, which might be able to serve as biomarkers for prognosis of ICC. Further studies focusing on these miRNAs may shed light on the mechanisms associated with ICC pathogenesis and progression." tissue_expression_ns hsa-mir-155 Respiratory Syncytial Virus Pneumonia 25884957 microRNA expression in nasal epithelium cytology brushings of RSV-positive infants shows a distinct profile of immune-associated miRNA.miR-125a has important functions within NF-¦ÊB signaling and macrophage function. The lack of downregulation of miR-125a and miR-429 in severe disease may help explain differences in disease manifestations on infection with RSV. tissue_expression_ns hsa-mir-16 Respiratory Syncytial Virus Pneumonia 25884957 microRNA expression in nasal epithelium cytology brushings of RSV-positive infants shows a distinct profile of immune-associated miRNA.miR-125a has important functions within NF-¦ÊB signaling and macrophage function. The lack of downregulation of miR-125a and miR-429 in severe disease may help explain differences in disease manifestations on infection with RSV. tissue_expression_ns hsa-mir-203a Respiratory Syncytial Virus Pneumonia 25884957 microRNA expression in nasal epithelium cytology brushings of RSV-positive infants shows a distinct profile of immune-associated miRNA.miR-125a has important functions within NF-¦ÊB signaling and macrophage function. The lack of downregulation of miR-125a and miR-429 in severe disease may help explain differences in disease manifestations on infection with RSV. tissue_expression_ns hsa-mir-27b Respiratory Syncytial Virus Pneumonia 25884957 microRNA expression in nasal epithelium cytology brushings of RSV-positive infants shows a distinct profile of immune-associated miRNA.miR-125a has important functions within NF-¦ÊB signaling and macrophage function. The lack of downregulation of miR-125a and miR-429 in severe disease may help explain differences in disease manifestations on infection with RSV. tissue_expression_ns hsa-mir-29c Respiratory Syncytial Virus Pneumonia 25884957 microRNA expression in nasal epithelium cytology brushings of RSV-positive infants shows a distinct profile of immune-associated miRNA.miR-125a has important functions within NF-¦ÊB signaling and macrophage function. The lack of downregulation of miR-125a and miR-429 in severe disease may help explain differences in disease manifestations on infection with RSV. tissue_expression_ns hsa-mir-31 Respiratory Syncytial Virus Pneumonia 25884957 microRNA expression in nasal epithelium cytology brushings of RSV-positive infants shows a distinct profile of immune-associated miRNA.miR-125a has important functions within NF-¦ÊB signaling and macrophage function. The lack of downregulation of miR-125a and miR-429 in severe disease may help explain differences in disease manifestations on infection with RSV. tissue_expression_ns hsa-mir-34b Respiratory Syncytial Virus Pneumonia 25884957 microRNA expression in nasal epithelium cytology brushings of RSV-positive infants shows a distinct profile of immune-associated miRNA.miR-125a has important functions within NF-¦ÊB signaling and macrophage function. The lack of downregulation of miR-125a and miR-429 in severe disease may help explain differences in disease manifestations on infection with RSV. tissue_expression_ns hsa-mir-34c Respiratory Syncytial Virus Pneumonia 25884957 microRNA expression in nasal epithelium cytology brushings of RSV-positive infants shows a distinct profile of immune-associated miRNA.miR-125a has important functions within NF-¦ÊB signaling and macrophage function. The lack of downregulation of miR-125a and miR-429 in severe disease may help explain differences in disease manifestations on infection with RSV. tissue_expression_ns hsa-mir-125b Breast Neoplasms 25886191 We were able to demonstrate for the first time the feasibility to detect distinct BC-dependent urinary miRNA profiles. The expression levels of four urinary miRNAs were specifically altered in our cohort of BC patients compared to healthy controls. This distinct pattern offers the possibility for a specific discrimination between healthy women and primary BC patients. This sustains the potential role of urinary miRNAs as non-invasive innovative urine-based biomarkers for BC detection. tissue_expression_ns hsa-mir-155 Breast Neoplasms 25886191 We were able to demonstrate for the first time the feasibility to detect distinct BC-dependent urinary miRNA profiles. The expression levels of four urinary miRNAs were specifically altered in our cohort of BC patients compared to healthy controls. This distinct pattern offers the possibility for a specific discrimination between healthy women and primary BC patients. This sustains the potential role of urinary miRNAs as non-invasive innovative urine-based biomarkers for BC detection. tissue_expression_ns hsa-mir-195 Breast Neoplasms 25886191 We were able to demonstrate for the first time the feasibility to detect distinct BC-dependent urinary miRNA profiles. The expression levels of four urinary miRNAs were specifically altered in our cohort of BC patients compared to healthy controls. This distinct pattern offers the possibility for a specific discrimination between healthy women and primary BC patients. This sustains the potential role of urinary miRNAs as non-invasive innovative urine-based biomarkers for BC detection. tissue_expression_ns hsa-mir-200b Breast Neoplasms 25886191 We were able to demonstrate for the first time the feasibility to detect distinct BC-dependent urinary miRNA profiles. The expression levels of four urinary miRNAs were specifically altered in our cohort of BC patients compared to healthy controls. This distinct pattern offers the possibility for a specific discrimination between healthy women and primary BC patients. This sustains the potential role of urinary miRNAs as non-invasive innovative urine-based biomarkers for BC detection. tissue_expression_ns hsa-mir-200c Breast Neoplasms 25886191 We were able to demonstrate for the first time the feasibility to detect distinct BC-dependent urinary miRNA profiles. The expression levels of four urinary miRNAs were specifically altered in our cohort of BC patients compared to healthy controls. This distinct pattern offers the possibility for a specific discrimination between healthy women and primary BC patients. This sustains the potential role of urinary miRNAs as non-invasive innovative urine-based biomarkers for BC detection. tissue_expression_ns hsa-mir-21 Breast Neoplasms 25886191 We were able to demonstrate for the first time the feasibility to detect distinct BC-dependent urinary miRNA profiles. The expression levels of four urinary miRNAs were specifically altered in our cohort of BC patients compared to healthy controls. This distinct pattern offers the possibility for a specific discrimination between healthy women and primary BC patients. This sustains the potential role of urinary miRNAs as non-invasive innovative urine-based biomarkers for BC detection. tissue_expression_ns hsa-mir-34a Breast Neoplasms 25886191 We were able to demonstrate for the first time the feasibility to detect distinct BC-dependent urinary miRNA profiles. The expression levels of four urinary miRNAs were specifically altered in our cohort of BC patients compared to healthy controls. This distinct pattern offers the possibility for a specific discrimination between healthy women and primary BC patients. This sustains the potential role of urinary miRNAs as non-invasive innovative urine-based biomarkers for BC detection. tissue_expression_ns hsa-mir-375 Breast Neoplasms 25886191 We were able to demonstrate for the first time the feasibility to detect distinct BC-dependent urinary miRNA profiles. The expression levels of four urinary miRNAs were specifically altered in our cohort of BC patients compared to healthy controls. This distinct pattern offers the possibility for a specific discrimination between healthy women and primary BC patients. This sustains the potential role of urinary miRNAs as non-invasive innovative urine-based biomarkers for BC detection. tissue_expression_ns hsa-mir-451 Breast Neoplasms 25886191 We were able to demonstrate for the first time the feasibility to detect distinct BC-dependent urinary miRNA profiles. The expression levels of four urinary miRNAs were specifically altered in our cohort of BC patients compared to healthy controls. This distinct pattern offers the possibility for a specific discrimination between healthy women and primary BC patients. This sustains the potential role of urinary miRNAs as non-invasive innovative urine-based biomarkers for BC detection. tissue_expression_ns hsa-mir-155 Liposarcoma 25888631 Deregulation of dicer and mir-155 expression in liposarcoma. tissue_expression_ns hsa-mir-29a Gastric Neoplasms 25889078 Our preliminary results suggest that altered expression of miR-29a-3p is involved in gastric cancer process. The present study provides the first insight into the specific role of miR-29a-3p in gastric carcinogenesis. tissue_expression_ns hsa-mir-145 Colorectal Carcinoma 25896668 "MiRNA-145 and miRNA-378* are potential biomarkers for early detection of CRC, which may help in diagnosing CRC in early period." tissue_expression_ns hsa-mir-378 Colorectal Carcinoma 25896668 "MiRNA-145 and miRNA-378* are potential biomarkers for early detection of CRC, which may help in diagnosing CRC in early period." tissue_expression_ns hsa-mir-198 "Adenocarcinoma, Pancreatic Ductal" 25908274 Our data suggest that altered expression of examined microRNAs is related to neoplastic transformation and progression of the disease and these microRNAs could serve as diagnostic and prognostic biomarkers for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-198 Chronic Pancreatitis 25908274 Our data suggest that altered expression of examined microRNAs is related to neoplastic transformation and progression of the disease and these microRNAs could serve as diagnostic and prognostic biomarkers for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 25908274 Our data suggest that altered expression of examined microRNAs is related to neoplastic transformation and progression of the disease and these microRNAs could serve as diagnostic and prognostic biomarkers for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-21 Chronic Pancreatitis 25908274 Our data suggest that altered expression of examined microRNAs is related to neoplastic transformation and progression of the disease and these microRNAs could serve as diagnostic and prognostic biomarkers for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-217 "Adenocarcinoma, Pancreatic Ductal" 25908274 Our data suggest that altered expression of examined microRNAs is related to neoplastic transformation and progression of the disease and these microRNAs could serve as diagnostic and prognostic biomarkers for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-217 Chronic Pancreatitis 25908274 Our data suggest that altered expression of examined microRNAs is related to neoplastic transformation and progression of the disease and these microRNAs could serve as diagnostic and prognostic biomarkers for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-34a "Adenocarcinoma, Pancreatic Ductal" 25908274 Our data suggest that altered expression of examined microRNAs is related to neoplastic transformation and progression of the disease and these microRNAs could serve as diagnostic and prognostic biomarkers for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-34a Chronic Pancreatitis 25908274 Our data suggest that altered expression of examined microRNAs is related to neoplastic transformation and progression of the disease and these microRNAs could serve as diagnostic and prognostic biomarkers for pancreatic ductal adenocarcinoma. tissue_expression_ns hsa-mir-106b "Carcinoma, Hepatocellular" 25916067 "A total of 54 differentially expressed miRNAs were identified, in which there were 13 miRNAs published to be related to HCC." tissue_expression_ns hsa-mir-205 Lung Neoplasms 25917317 MiR-205 and miR-218 expression is associated with carboplatin chemoresistance and regulation of apoptosis via Mcl-1 and Survivin in lung cancer cells. tissue_expression_ns hsa-mir-218 Lung Neoplasms 25917317 MiR-205 and miR-218 expression is associated with carboplatin chemoresistance and regulation of apoptosis via Mcl-1 and Survivin in lung cancer cells. tissue_expression_ns hsa-mir-10a "Carcinoma, Cervical" 25920605 This meta-analysis has identified several miRNAs whose expression correlates reliably with cervical cancer. These should be probed in further studies to explore their potential as diagnostic biomarkers. tissue_expression_ns hsa-mir-141 "Carcinoma, Cervical" 25920605 This meta-analysis has identified several miRNAs whose expression correlates reliably with cervical cancer. These should be probed in further studies to explore their potential as diagnostic biomarkers. tissue_expression_ns hsa-mir-143 "Carcinoma, Cervical" 25920605 This meta-analysis has identified several miRNAs whose expression correlates reliably with cervical cancer. These should be probed in further studies to explore their potential as diagnostic biomarkers. tissue_expression_ns hsa-mir-145 "Carcinoma, Cervical" 25920605 This meta-analysis has identified several miRNAs whose expression correlates reliably with cervical cancer. These should be probed in further studies to explore their potential as diagnostic biomarkers. tissue_expression_ns hsa-mir-15b "Carcinoma, Cervical" 25920605 This meta-analysis has identified several miRNAs whose expression correlates reliably with cervical cancer. These should be probed in further studies to explore their potential as diagnostic biomarkers. tissue_expression_ns hsa-mir-200a "Carcinoma, Cervical" 25920605 This meta-analysis has identified several miRNAs whose expression correlates reliably with cervical cancer. These should be probed in further studies to explore their potential as diagnostic biomarkers. tissue_expression_ns hsa-mir-203 "Carcinoma, Cervical" 25920605 This meta-analysis has identified several miRNAs whose expression correlates reliably with cervical cancer. These should be probed in further studies to explore their potential as diagnostic biomarkers. tissue_expression_ns hsa-mir-20a "Carcinoma, Cervical" 25920605 This meta-analysis has identified several miRNAs whose expression correlates reliably with cervical cancer. These should be probed in further studies to explore their potential as diagnostic biomarkers. tissue_expression_ns hsa-mir-20b "Carcinoma, Cervical" 25920605 This meta-analysis has identified several miRNAs whose expression correlates reliably with cervical cancer. These should be probed in further studies to explore their potential as diagnostic biomarkers. tissue_expression_ns hsa-mir-224 "Carcinoma, Cervical" 25920605 This meta-analysis has identified several miRNAs whose expression correlates reliably with cervical cancer. These should be probed in further studies to explore their potential as diagnostic biomarkers. tissue_expression_ns hsa-mir-148 "Adenocarcinoma, Esophageal" 25928282 "Our data suggest that altered expression of miR-21, miR-29c, miR-148 and miR-203 are related to neoplastic transformation and progression of the disease and these microRNAs could serve as a potential diagnostic and prognostic biomarkers in esophageal cancer." tissue_expression_ns hsa-mir-148 "Squamous Cell Carcinoma, Esophageal" 25928282 "Our data suggest that altered expression of miR-21, miR-29c, miR-148 and miR-203 are related to neoplastic transformation and progression of the disease and these microRNAs could serve as a potential diagnostic and prognostic biomarkers in esophageal cancer." tissue_expression_ns hsa-mir-203 "Adenocarcinoma, Esophageal" 25928282 "Our data suggest that altered expression of miR-21, miR-29c, miR-148 and miR-203 are related to neoplastic transformation and progression of the disease and these microRNAs could serve as a potential diagnostic and prognostic biomarkers in esophageal cancer." tissue_expression_ns hsa-mir-203 "Squamous Cell Carcinoma, Esophageal" 25928282 "Our data suggest that altered expression of miR-21, miR-29c, miR-148 and miR-203 are related to neoplastic transformation and progression of the disease and these microRNAs could serve as a potential diagnostic and prognostic biomarkers in esophageal cancer." tissue_expression_ns hsa-mir-21 "Adenocarcinoma, Esophageal" 25928282 "Our data suggest that altered expression of miR-21, miR-29c, miR-148 and miR-203 are related to neoplastic transformation and progression of the disease and these microRNAs could serve as a potential diagnostic and prognostic biomarkers in esophageal cancer." tissue_expression_ns hsa-mir-21 "Squamous Cell Carcinoma, Esophageal" 25928282 "Our data suggest that altered expression of miR-21, miR-29c, miR-148 and miR-203 are related to neoplastic transformation and progression of the disease and these microRNAs could serve as a potential diagnostic and prognostic biomarkers in esophageal cancer." tissue_expression_ns hsa-mir-29c "Adenocarcinoma, Esophageal" 25928282 "Our data suggest that altered expression of miR-21, miR-29c, miR-148 and miR-203 are related to neoplastic transformation and progression of the disease and these microRNAs could serve as a potential diagnostic and prognostic biomarkers in esophageal cancer." tissue_expression_ns hsa-mir-29c "Squamous Cell Carcinoma, Esophageal" 25928282 "Our data suggest that altered expression of miR-21, miR-29c, miR-148 and miR-203 are related to neoplastic transformation and progression of the disease and these microRNAs could serve as a potential diagnostic and prognostic biomarkers in esophageal cancer." tissue_expression_ns hsa-mir-29a "Carcinoma, Renal Cell, Clear-Cell" 25938468 "This study identified 11 commonly dysregulated miRNAs in ccRCC,three of which (miR-199a-5p, miR-22 and miR-429) may represent key miRNAs involved in the pathogenesis of ccRCC. Further studies suggested that miR-199a-5p plays an important role in inhibition of cell invasion of ccRCC cells by suppressing expression of TGFBR1 and JunB." tissue_expression_ns hsa-mir-429 "Carcinoma, Renal Cell, Clear-Cell" 25938468 "This study identified 11 commonly dysregulated miRNAs in ccRCC,three of which (miR-199a-5p, miR-22 and miR-429) may represent key miRNAs involved in the pathogenesis of ccRCC. Further studies suggested that miR-199a-5p plays an important role in inhibition of cell invasion of ccRCC cells by suppressing expression of TGFBR1 and JunB." tissue_expression_ns hsa-mir-452 "Carcinoma, Renal Cell, Clear-Cell" 25938468 "This study identified 11 commonly dysregulated miRNAs in ccRCC,three of which (miR-199a-5p, miR-22 and miR-429) may represent key miRNAs involved in the pathogenesis of ccRCC. Further studies suggested that miR-199a-5p plays an important role in inhibition of cell invasion of ccRCC cells by suppressing expression of TGFBR1 and JunB." tissue_expression_ns hsa-mir-487a "Carcinoma, Renal Cell, Clear-Cell" 25938468 "This study identified 11 commonly dysregulated miRNAs in ccRCC,three of which (miR-199a-5p, miR-22 and miR-429) may represent key miRNAs involved in the pathogenesis of ccRCC. Further studies suggested that miR-199a-5p plays an important role in inhibition of cell invasion of ccRCC cells by suppressing expression of TGFBR1 and JunB." tissue_expression_ns hsa-mir-491 "Carcinoma, Renal Cell, Clear-Cell" 25938468 "This study identified 11 commonly dysregulated miRNAs in ccRCC,three of which (miR-199a-5p, miR-22 and miR-429) may represent key miRNAs involved in the pathogenesis of ccRCC. Further studies suggested that miR-199a-5p plays an important role in inhibition of cell invasion of ccRCC cells by suppressing expression of TGFBR1 and JunB." tissue_expression_ns hsa-mir-532 "Carcinoma, Renal Cell, Clear-Cell" 25938468 "This study identified 11 commonly dysregulated miRNAs in ccRCC,three of which (miR-199a-5p, miR-22 and miR-429) may represent key miRNAs involved in the pathogenesis of ccRCC. Further studies suggested that miR-199a-5p plays an important role in inhibition of cell invasion of ccRCC cells by suppressing expression of TGFBR1 and JunB." tissue_expression_ns hsa-mir-21 Rectal Neoplasms 25953218 MicroRNA-21 expression efficiently predicts preoperative chemoradiotherapy pathological response in locally advanced rectal cancer. tissue_expression_ns hsa-mir-34a Glioma 25953448 "The top 20 potential miRNAs including MIR-124A, MIR-34A and MIR-34C were screened for a constructing gene-miRNA interaction network." tissue_expression_ns hsa-mir-4489 Glioma 25954994 The dysregulated miRNAs identified in the present study contribute to the tumorigenesis and malignant progression of gliomas and may serve as useful markers for advanced glioma pathological grading and prognosis. tissue_expression_ns hsa-mir-196b "Carcinoma, Ovarian" 25964536 "Based on our data, dysregulation of microRNA expression was associated with the recurrence of EOC. Moreover, significantly over- and down-regulated microRNAs can be useful biomarkers for the prediction of recurrence in EOC." tissue_expression_ns hsa-mir-19b "Carcinoma, Ovarian" 25964536 "Based on our data, dysregulation of microRNA expression was associated with the recurrence of EOC. Moreover, significantly over- and down-regulated microRNAs can be useful biomarkers for the prediction of recurrence in EOC." tissue_expression_ns hsa-mir-3198 "Carcinoma, Ovarian" 25964536 "Based on our data, dysregulation of microRNA expression was associated with the recurrence of EOC. Moreover, significantly over- and down-regulated microRNAs can be useful biomarkers for the prediction of recurrence in EOC." tissue_expression_ns hsa-mir-3201 "Carcinoma, Ovarian" 25964536 "Based on our data, dysregulation of microRNA expression was associated with the recurrence of EOC. Moreover, significantly over- and down-regulated microRNAs can be useful biomarkers for the prediction of recurrence in EOC." tissue_expression_ns hsa-mir-3613 "Carcinoma, Ovarian" 25964536 "Based on our data, dysregulation of microRNA expression was associated with the recurrence of EOC. Moreover, significantly over- and down-regulated microRNAs can be useful biomarkers for the prediction of recurrence in EOC." tissue_expression_ns hsa-mir-551b "Carcinoma, Ovarian" 25964536 "Based on our data, dysregulation of microRNA expression was associated with the recurrence of EOC. Moreover, significantly over- and down-regulated microRNAs can be useful biomarkers for the prediction of recurrence in EOC." tissue_expression_ns hsa-mir-7515 "Carcinoma, Ovarian" 25964536 "Based on our data, dysregulation of microRNA expression was associated with the recurrence of EOC. Moreover, significantly over- and down-regulated microRNAs can be useful biomarkers for the prediction of recurrence in EOC." tissue_expression_ns hsa-mir-8084 "Carcinoma, Ovarian" 25964536 "Based on our data, dysregulation of microRNA expression was associated with the recurrence of EOC. Moreover, significantly over- and down-regulated microRNAs can be useful biomarkers for the prediction of recurrence in EOC." tissue_expression_ns hsa-mir-155 Cardiovascular Diseases [unspecific] 25978529 microRNA expression patterns have a low diagnostic potential clinically in discriminating DCD liver quality and outcome. tissue_expression_ns hsa-mir-22 Cardiovascular Diseases [unspecific] 25978529 microRNA expression patterns have a low diagnostic potential clinically in discriminating DCD liver quality and outcome. tissue_expression_ns hsa-mir-940 Cardiovascular Diseases [unspecific] 25978529 microRNA expression patterns have a low diagnostic potential clinically in discriminating DCD liver quality and outcome. tissue_expression_ns hsa-mir-191 "Carcinoma, Renal Cell, Chromophobe" 25981392 "mir-191, mir-19a, mir-210, and mir-425 miRNAs are expressed differentially in chRCC, and unique expression of miRNAs is associated with the progression and prognosis of chRCC." tissue_expression_ns hsa-mir-19a "Carcinoma, Renal Cell, Chromophobe" 25981392 "mir-191, mir-19a, mir-210, and mir-425 miRNAs are expressed differentially in chRCC, and unique expression of miRNAs is associated with the progression and prognosis of chRCC." tissue_expression_ns hsa-mir-210 "Carcinoma, Renal Cell, Chromophobe" 25981392 "mir-191, mir-19a, mir-210, and mir-425 miRNAs are expressed differentially in chRCC, and unique expression of miRNAs is associated with the progression and prognosis of chRCC." tissue_expression_ns hsa-mir-425 "Carcinoma, Renal Cell, Chromophobe" 25981392 "mir-191, mir-19a, mir-210, and mir-425 miRNAs are expressed differentially in chRCC, and unique expression of miRNAs is associated with the progression and prognosis of chRCC." tissue_expression_ns hsa-let-7c "Carcinoma, Bladder" 25990459 this study identified the specific miRNAs associated with the progression and aggressiveness of MIBC and a four-miRNA signature as a promising prognostic parameter of MIBC. tissue_expression_ns hsa-mir-125b-1 "Carcinoma, Bladder" 25990459 this study identified the specific miRNAs associated with the progression and aggressiveness of MIBC and a four-miRNA signature as a promising prognostic parameter of MIBC. tissue_expression_ns hsa-mir-193a "Carcinoma, Bladder" 25990459 this study identified the specific miRNAs associated with the progression and aggressiveness of MIBC and a four-miRNA signature as a promising prognostic parameter of MIBC. tissue_expression_ns hsa-mir-99a "Carcinoma, Bladder" 25990459 this study identified the specific miRNAs associated with the progression and aggressiveness of MIBC and a four-miRNA signature as a promising prognostic parameter of MIBC. tissue_expression_ns hsa-mir-373 Neoplasms [unspecific] 25990556 "Deregulation of miR-373 has been demonstrated in a number of cancers, whether it acts as an oncogene or a tumor suppressor, however, seems to be context dependent. In this review, we focus on the diverse functions of miR-373 and its implication in cancers." tissue_expression_ns hsa-let-7 Neoplasms [unspecific] 25998712 "together with the recent identification of novel miRNA regulatory factors and pathways, highlights the importance of miRNA dysregulation in cancer." tissue_expression_ns hsa-mir-15 Neoplasms [unspecific] 25998712 "together with the recent identification of novel miRNA regulatory factors and pathways, highlights the importance of miRNA dysregulation in cancer." tissue_expression_ns hsa-mir-16 Neoplasms [unspecific] 25998712 "together with the recent identification of novel miRNA regulatory factors and pathways, highlights the importance of miRNA dysregulation in cancer." tissue_expression_ns hsa-mir-222 "Adenocarcinoma, Pancreatic Ductal" 26002251 "we found significant adjusted HRs for poor OS for high miR-155, high miR-203, and low miR-34a; and unadjusted HRs for high miR-222 and high miR-10b." tissue_expression_ns hsa-mir-1 Colorectal Carcinoma 26045793 The potential value of miR-1 and miR-374b as biomarkers for colorectal cancer. tissue_expression_ns hsa-mir-191 Acute Myocardial Infarction 26046358 "This study highlights the stability of miRNAs after death and long-term fixation, validating their use as reliable biomarkers for AMI during postmortem examination." tissue_expression_ns hsa-mir-26b Acute Myocardial Infarction 26046358 "This study highlights the stability of miRNAs after death and long-term fixation, validating their use as reliable biomarkers for AMI during postmortem examination." tissue_expression_ns hsa-mir-30a "Carcinoma, Thyroid, Papillary" 26047355 The results of this study suggest that miR-30a-5p might be a novel diagnostic marker candidate in PTC. Further studies are required to investigate this possibility. tissue_expression_ns hsa-mir-126 "Carcinoma, Breast, Triple Negative" 26062749 "This study provides strong evidence that the expression levels of miR-374b-5p, miR-27b-3p, miR-126-3p, and miR-218-5p in tumor tissues predict TNBC outcomes." tissue_expression_ns hsa-mir-218 "Carcinoma, Breast, Triple Negative" 26062749 "This study provides strong evidence that the expression levels of miR-374b-5p, miR-27b-3p, miR-126-3p, and miR-218-5p in tumor tissues predict TNBC outcomes." tissue_expression_ns hsa-mir-27b "Carcinoma, Breast, Triple Negative" 26062749 "This study provides strong evidence that the expression levels of miR-374b-5p, miR-27b-3p, miR-126-3p, and miR-218-5p in tumor tissues predict TNBC outcomes." tissue_expression_ns hsa-mir-374b "Carcinoma, Breast, Triple Negative" 26062749 "This study provides strong evidence that the expression levels of miR-374b-5p, miR-27b-3p, miR-126-3p, and miR-218-5p in tumor tissues predict TNBC outcomes." tissue_expression_ns hsa-mir-31 "Squamous Cell Carcinoma, Oral" 26104160 "MiR-31 and miR-130b, known to inhibit several steps in the metastatic process, were over-expressed in non-metastatic samples and the expression of miR-130b was confirmed in plasma of patients showing no metastasis." tissue_expression_ns hsa-mir-34a "Adenocarcinoma, Lung" 26104764 The expression of microRNA-34a is inversely correlated with c-MET and CDK6 and has a prognostic significance in lung adenocarcinoma patients. tissue_expression_ns hsa-let-7a Breast Neoplasms 26130254 "Relative levels of let-7a, miR-17, miR-27b, miR-125a, miR-125b and miR-206 as potential molecular markers to evaluate grade, receptor status and molecular type in breast cancer." tissue_expression_ns hsa-mir-130b Breast Neoplasms 26152113 Comparative microRNA profiling of sporadic and BRCA1 associated basal-like breast cancers tissue_expression_ns hsa-mir-149 Breast Neoplasms 26152113 Comparative microRNA profiling of sporadic and BRCA2 associated basal-like breast cancers tissue_expression_ns hsa-mir-190b Breast Neoplasms 26152113 Comparative microRNA profiling of sporadic and BRCA3 associated basal-like breast cancers tissue_expression_ns hsa-mir-198 Breast Neoplasms 26152113 Comparative microRNA profiling of sporadic and BRCA4 associated basal-like breast cancers tissue_expression_ns hsa-mir-218 Breast Neoplasms 26152113 Comparative microRNA profiling of sporadic and BRCA5 associated basal-like breast cancers tissue_expression_ns hsa-mir-374b Breast Neoplasms 26152113 Comparative microRNA profiling of sporadic and BRCA7 associated basal-like breast cancers tissue_expression_ns hsa-mir-590 Breast Neoplasms 26152113 Comparative microRNA profiling of sporadic and BRCA6 associated basal-like breast cancers tissue_expression_ns hsa-mir-892a Breast Neoplasms 26152113 Comparative microRNA profiling of sporadic and BRCA8 associated basal-like breast cancers tissue_expression_ns hsa-mir-196b Crohn Disease 26164662 "We found a suite of miRNAs, including miR-31-5p, miR-215, miR-223-3p, miR-196b-5p, and miR-203 that stratify patients with CD according to disease behavior independent of the effect of inflammation." tissue_expression_ns hsa-mir-203 Crohn Disease 26164662 "We found a suite of miRNAs, including miR-31-5p, miR-215, miR-223-3p, miR-196b-5p, and miR-203 that stratify patients with CD according to disease behavior independent of the effect of inflammation." tissue_expression_ns hsa-mir-1-2 Gastric Neoplasms 26168960 "mir-17, mir-133b, mir-133a-2, and mir-1-2 appear to be a potential novel predictor of tumor stage and preoperative and intraoperative diagnosis." tissue_expression_ns hsa-mir-133a-2 Gastric Neoplasms 26168960 "mir-17, mir-133b, mir-133a-2, and mir-1-2 appear to be a potential novel predictor of tumor stage and preoperative and intraoperative diagnosis." tissue_expression_ns hsa-mir-133b Gastric Neoplasms 26168960 "mir-17, mir-133b, mir-133a-2, and mir-1-2 appear to be a potential novel predictor of tumor stage and preoperative and intraoperative diagnosis." tissue_expression_ns hsa-mir-17 Gastric Neoplasms 26168960 "mir-17, mir-133b, mir-133a-2, and mir-1-2 appear to be a potential novel predictor of tumor stage and preoperative and intraoperative diagnosis." tissue_expression_ns hsa-mir-23a "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 26175945 MiR-21/miR-375 ratio is an independent prognostic factor in patients with laryngeal squamous cell carcinoma. tissue_expression_ns hsa-mir-126 Osteosarcoma 26194657 Tissue microRNA-126 expression level predicts outcome in human osteosarcoma. tissue_expression_ns hsa-mir-148a Breast Neoplasms 26199650 "Based on the results obtained in the last decade, some miRNAs are emerging as biomarkers of BC for diagnosis (i.e., miR-9, miR-10b, and miR-17-5p), prognosis (i.e., miR-148a and miR-335)" tissue_expression_ns hsa-mir-122 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-125a "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-129 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-133b "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-142 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-192 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-194 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-195 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-198 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-199a "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-20 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-200a "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-215 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-223 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-224 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-24 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-25 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-26b "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-27a "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-29a "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-29b "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-320 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-369 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-491 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-512 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-522 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-542 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-576 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-651 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-92 "Carcinoma, Hepatocellular" 26229398 "In summary, all the reported results suggest that differences in miRNA expression exist between HCV-related and HCV-negative NHLs, and further studies will be useful to ascertain if miRNAs are involved in the pathogenesis of HCV-related lymphomas and whether they can be used as biomarkers." tissue_expression_ns hsa-mir-130a "Carcinoma, Hepatocellular" 26231037 Systematic and integrative analysis of published datesets that compared the miRNA expression profiles between hepatocellular carcinoma (HCC) tissue and paired adjacent noncancerous liver tissue was performed to determine candidate HCC associated miRNAs. tissue_expression_ns hsa-mir-21 "Carcinoma, Hepatocellular" 26231037 Systematic and integrative analysis of published datesets that compared the miRNA expression profiles between hepatocellular carcinoma (HCC) tissue and paired adjacent noncancerous liver tissue was performed to determine candidate HCC associated miRNAs. tissue_expression_ns hsa-mir-214 "Carcinoma, Hepatocellular" 26231037 Systematic and integrative analysis of published datesets that compared the miRNA expression profiles between hepatocellular carcinoma (HCC) tissue and paired adjacent noncancerous liver tissue was performed to determine candidate HCC associated miRNAs. tissue_expression_ns hsa-mir-221 "Carcinoma, Hepatocellular" 26231037 Systematic and integrative analysis of published datesets that compared the miRNA expression profiles between hepatocellular carcinoma (HCC) tissue and paired adjacent noncancerous liver tissue was performed to determine candidate HCC associated miRNAs. tissue_expression_ns hsa-mir-186 Glioma 26231038 CRNDE affects the malignant biological characteristics of human glioma stem cells by negatively regulating miR-186. tissue_expression_ns hsa-mir-15a "Carcinoma, Thyroid, Papillary" 26252081 "We found that the area under the curve (AUC) values of 8 miRNAs (miR-106a, miR-15a, miR-30a, miR-30b, miR-20a, miR-20b, miR-30d and miR-30e)" tissue_expression_ns hsa-mir-20a "Carcinoma, Thyroid, Papillary" 26252081 "We found that the area under the curve (AUC) values of 8 miRNAs (miR-106a, miR-15a, miR-30a, miR-30b, miR-20a, miR-20b, miR-30d and miR-30e)" tissue_expression_ns hsa-mir-30e "Carcinoma, Thyroid, Papillary" 26252081 "We found that the area under the curve (AUC) values of 8 miRNAs (miR-106a, miR-15a, miR-30a, miR-30b, miR-20a, miR-20b, miR-30d and miR-30e)" tissue_expression_ns hsa-mir-320 Melanoma 26264058 "hsa-miR-519, ""hsa-miR-431"" and ""hsa-miR-320c"" are possible novel predictions for renal cancer, lung cancer and melanoma, respectively." tissue_expression_ns hsa-mir-182 Melanoma 26273328 Clinical analyses demonstrated the link of miR-182 expression to poor prognosis in cancer patients. tissue_expression_ns hsa-mir-4793 Necrotizing Enterocolitis 26274503 "The robust response of miRNA dysregulation in NEC and SIP, and concerted involvement of specific miRNAs in the molecular networks indicated their crucial roles in mucosa integrity and disease pathophysiology." tissue_expression_ns hsa-mir-1290 Necrotizing Enterocolitis 26274503 "The robust response of miRNA dysregulation in NEC and SIP, and concerted involvement of specific miRNAs in the molecular networks indicated their crucial roles in mucosa integrity and disease pathophysiology." tissue_expression_ns hsa-mir-194 Necrotizing Enterocolitis 26274503 "The robust response of miRNA dysregulation in NEC and SIP, and concerted involvement of specific miRNAs in the molecular networks indicated their crucial roles in mucosa integrity and disease pathophysiology." tissue_expression_ns hsa-mir-203 Necrotizing Enterocolitis 26274503 "The robust response of miRNA dysregulation in NEC and SIP, and concerted involvement of specific miRNAs in the molecular networks indicated their crucial roles in mucosa integrity and disease pathophysiology." tissue_expression_ns hsa-mir-21 Necrotizing Enterocolitis 26274503 "The robust response of miRNA dysregulation in NEC and SIP, and concerted involvement of specific miRNAs in the molecular networks indicated their crucial roles in mucosa integrity and disease pathophysiology." tissue_expression_ns hsa-mir-31 Necrotizing Enterocolitis 26274503 "The robust response of miRNA dysregulation in NEC and SIP, and concerted involvement of specific miRNAs in the molecular networks indicated their crucial roles in mucosa integrity and disease pathophysiology." tissue_expression_ns hsa-mir-431 Necrotizing Enterocolitis 26274503 "The robust response of miRNA dysregulation in NEC and SIP, and concerted involvement of specific miRNAs in the molecular networks indicated their crucial roles in mucosa integrity and disease pathophysiology." tissue_expression_ns hsa-mir-451 Necrotizing Enterocolitis 26274503 "The robust response of miRNA dysregulation in NEC and SIP, and concerted involvement of specific miRNAs in the molecular networks indicated their crucial roles in mucosa integrity and disease pathophysiology." tissue_expression_ns hsa-mir-23b "Carcinoma, Adenoid Cystic" 26293217 Expression of miR-23b and miR-27b differed between normal breast and normal salivary gland tissue tissue_expression_ns hsa-mir-22 Neoplasms [unspecific] 26295583 Genome Wide Expression Profiling of Cancer Cell Lines Cultured in Microgravity Reveals Significant Dysregulation of Cell Cycle and MicroRNA Gene Networks. tissue_expression_ns hsa-mir-16 Neoplasms [unspecific] 26299954 Genome-wide analysis of microRNA and mRNA expression signatures in cancer. tissue_expression_ns hsa-mir-191 Neoplasms [unspecific] 26299954 Genome-wide analysis of microRNA and mRNA expression signatures in cancer. tissue_expression_ns hsa-mir-93 Neoplasms [unspecific] 26299954 Genome-wide analysis of microRNA and mRNA expression signatures in cancer. tissue_expression_ns hsa-mir-31 Inflammation 26303911 "We identified three miRNAs, miR-497, miR-351 and miR-31, that are candidate master regulators of genes associated with neutrophil recruitment." tissue_expression_ns hsa-mir-16 Endometriosis 26307093 Peritoneal fluid modifies the microRNA expression profile in endometrial and endometriotic cells from women with endometriosis. tissue_expression_ns hsa-mir-29c Endometriosis 26307093 Peritoneal fluid modifies the microRNA expression profile in endometrial and endometriotic cells from women with endometriosis. tissue_expression_ns hsa-mir-424 Endometriosis 26307093 Peritoneal fluid modifies the microRNA expression profile in endometrial and endometriotic cells from women with endometriosis. tissue_expression_ns hsa-mir-200c Uterine Corpus Myxoid Leiomyosarcoma 26307392 Malignant tumors of the uterine corpus: molecular background of their origin. tissue_expression_ns hsa-mir-146b "Carcinoma, Thyroid, Papillary" 26321247 miRNA-222 and miRNA-146b deregulation are commonly associated with cancer recurrence in patients with papillary thyroid carcinoma. tissue_expression_ns hsa-mir-222 "Carcinoma, Thyroid, Papillary" 26321247 miRNA-222 and miRNA-146b deregulation are commonly associated with cancer recurrence in patients with papillary thyroid carcinoma. tissue_expression_ns hsa-mir-34b "Carcinoma, Nasopharyngeal" 26330189 Integrated analysis of the differential cellular and EBV miRNA expression profiles in microdissected nasopharyngeal carcinoma and non-cancerous nasopharyngeal tissues. tissue_expression_ns hsa-mir-1 "Carcinoma, Breast" 26331797 These findings suggest that abnormal miR-1 expression is associated with an aggressive phenotype of breast carcinoma and that miR-1 status is a potent prognostic factor in human breast cancer patients. tissue_expression_ns hsa-mir-145 Colorectal Carcinoma 26335822 The analysis of microRNAs miR-200c and miR-145 expression in colorectal cancer of different molecular subtypes. tissue_expression_ns hsa-mir-200c Colorectal Carcinoma 26335822 The analysis of microRNAs miR-200c and miR-145 expression in colorectal cancer of different molecular subtypes. tissue_expression_ns hsa-mir-21 Choriocarcinoma 26338526 Statistical analysis of a Bayesian classifier based on the expression of miRNAs. tissue_expression_ns hsa-mir-451 Endometriosis 26370665 Altered expression of microRNA-451 in eutopic endometrium of baboons (Papioanubis) with endometriosis. tissue_expression_ns hsa-mir-181c "Carcinoma, Urothelial, Upper Tract" 26397152 Differential microRNA expression in aristolochic acid-induced upper urothelial tract cancers ex vivo. tissue_expression_ns hsa-mir-330 "Carcinoma, Urothelial, Upper Tract" 26397152 Differential microRNA expression in aristolochic acid-induced upper urothelial tract cancers ex vivo. tissue_expression_ns hsa-mir-3916 "Carcinoma, Urothelial, Upper Tract" 26397152 Differential microRNA expression in aristolochic acid-induced upper urothelial tract cancers ex vivo. tissue_expression_ns hsa-mir-4274 "Carcinoma, Urothelial, Upper Tract" 26397152 Differential microRNA expression in aristolochic acid-induced upper urothelial tract cancers ex vivo. tissue_expression_ns hsa-mir-4784 "Carcinoma, Urothelial, Upper Tract" 26397152 Differential microRNA expression in aristolochic acid-induced upper urothelial tract cancers ex vivo. tissue_expression_ns hsa-mir-4795 "Carcinoma, Urothelial, Upper Tract" 26397152 Differential microRNA expression in aristolochic acid-induced upper urothelial tract cancers ex vivo. tissue_expression_ns hsa-mir-488 "Carcinoma, Urothelial, Upper Tract" 26397152 Differential microRNA expression in aristolochic acid-induced upper urothelial tract cancers ex vivo. tissue_expression_ns hsa-mir-203 "Carcinoma, Lung" 26397233 "Cumulatively,our data purport that p53 not only increased Puma expression directly, but that it may also do so through miR-203. Additionally, functional studies revealed that miR-203 overexpression induced apoptosis and inhibited cell invasiveness." tissue_expression_ns hsa-mir-203 Colon Neoplasms 26397233 "Cumulatively,our data purport that p53 not only increased Puma expression directly, but that it may also do so through miR-203. Additionally, functional studies revealed that miR-203 overexpression induced apoptosis and inhibited cell invasiveness." tissue_expression_ns hsa-mir-1 Muscular Dystrophy 26398013 "whereas down-regulation of myogenic miRNAs, including miR-1 and miR-206, is associated with inhibition of muscle regeneration." tissue_expression_ns hsa-mir-125b Neoplasms [unspecific] 26407906 The aberrant expression of miR-125 familyis tightly related to tumorigenesis and tumor development. tissue_expression_ns hsa-mir-1271 "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-130b "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-135b "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-146b "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-151 "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-181b "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-199b "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-21 "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-221 "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-222 "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-2861 "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-34b "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-451 "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-623 "Carcinoma, Thyroid, Papillary" 26414548 Further studies are needed to investigate whether miRs are independent predictors of aggressive clinicopathologic features before it can be recommended that miR expression levels should be incorporated into the management algorithm for patients with PTC. A well-designed prospective study is needed to assess these potential associations. tissue_expression_ns hsa-mir-126 Colorectal Carcinoma 26455548 "To conclude, deregulation of miR-126 in colorectal cancer at the tissue and cellular levels as well as its correlation with various clinicopathological parameters confirm the cancer suppressive role of miR-126 in colorectal cancer." tissue_expression_ns hsa-mir-139 Colorectal Carcinoma 26462034 Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validation. tissue_expression_ns hsa-mir-143 Colorectal Carcinoma 26462034 Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validation. tissue_expression_ns hsa-mir-145 Colorectal Carcinoma 26462034 Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validation. tissue_expression_ns hsa-mir-17 Colorectal Carcinoma 26462034 Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validation. tissue_expression_ns hsa-mir-183 Colorectal Carcinoma 26462034 Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validation. tissue_expression_ns hsa-mir-195 Colorectal Carcinoma 26462034 Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validation. tissue_expression_ns hsa-mir-20a Colorectal Carcinoma 26462034 Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validation. tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 26462034 Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validation. tissue_expression_ns hsa-mir-378a Colorectal Carcinoma 26462034 Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validation. tissue_expression_ns hsa-mir-17 "Carcinoma, Colon" 26465597 "It is concluded that the expression of miR-17, miR-21, and miR-145 changes at early stages of the normal-adenoma-adenocarcinoma sequence. Thus, these microRNAs may play a role in the development of colon cancer." tissue_expression_ns hsa-mir-18 "Carcinoma, Colon" 26465597 "It is concluded that the expression of miR-17, miR-21, and miR-145 changes at early stages of the normal-adenoma-adenocarcinoma sequence. Thus, these microRNAs may play a role in the development of colon cancer." tissue_expression_ns hsa-mir-19a "Carcinoma, Colon" 26465597 "It is concluded that the expression of miR-17, miR-21, and miR-145 changes at early stages of the normal-adenoma-adenocarcinoma sequence. Thus, these microRNAs may play a role in the development of colon cancer." tissue_expression_ns hsa-mir-19b-1 "Carcinoma, Colon" 26465597 "It is concluded that the expression of miR-17, miR-21, and miR-145 changes at early stages of the normal-adenoma-adenocarcinoma sequence. Thus, these microRNAs may play a role in the development of colon cancer." tissue_expression_ns hsa-mir-20a "Carcinoma, Colon" 26465597 "It is concluded that the expression of miR-17, miR-21, and miR-145 changes at early stages of the normal-adenoma-adenocarcinoma sequence. Thus, these microRNAs may play a role in the development of colon cancer." tissue_expression_ns hsa-mir-92-1 "Carcinoma, Colon" 26465597 "It is concluded that the expression of miR-17, miR-21, and miR-145 changes at early stages of the normal-adenoma-adenocarcinoma sequence. Thus, these microRNAs may play a role in the development of colon cancer." tissue_expression_ns hsa-mir-99b Inflammatory Bowel Diseases 26466382 "These results suggest that the proposed miRNA signature is of relevance for the etiology of IBD. Its diagnostic value, however, should be further evaluated in large, independent, clinically well characterized cohorts." tissue_expression_ns hsa-mir-182 Prostate Neoplasms 26484677 "Integrated Analysis Reveals together miR-182, miR-200c and miR-221 Can Help in the Diagnosis of Prostate Cancer." tissue_expression_ns hsa-mir-200c Prostate Neoplasms 26484677 "Integrated Analysis Reveals together miR-182, miR-200c and miR-221 Can Help in the Diagnosis of Prostate Cancer." tissue_expression_ns hsa-mir-221 Prostate Neoplasms 26484677 "Integrated Analysis Reveals together miR-182, miR-200c and miR-221 Can Help in the Diagnosis of Prostate Cancer." tissue_expression_ns hsa-mir-100 Bladder Neoplasms 26489968 MiRNAs detected in urine and serum/plasma will demonstrate their potentiality to describe the variegated scenario of BC and to become relevant clinical markers. tissue_expression_ns hsa-let-7g Alzheimer Disease 26497684 Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease. tissue_expression_ns hsa-let-7g Parkinson Disease 26497684 Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease. tissue_expression_ns hsa-mir-10a Alzheimer Disease 26497684 Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease. tissue_expression_ns hsa-mir-10a Parkinson Disease 26497684 Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease. tissue_expression_ns hsa-mir-153 Alzheimer Disease 26497684 Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease. tissue_expression_ns hsa-mir-153 Parkinson Disease 26497684 Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease. tissue_expression_ns hsa-mir-409 Alzheimer Disease 26497684 Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease. tissue_expression_ns hsa-mir-409 Parkinson Disease 26497684 Altered microRNA profiles in cerebrospinal fluid exosome in Parkinson disease and Alzheimer disease. tissue_expression_ns hsa-mir-510 "Carcinoma, Ovarian" 26497752 "Profile of differentially expressed miRNAs in high-grade serous carcinoma and clear cell ovarian carcinoma, and the expression of miR-510 in ovarian carcinoma." tissue_expression_ns hsa-mir-30c "Carcinoma, Prostate" 26499781 The average relative expressions of hsa-miR-203 and hsa-miR-30c in tumor tissues were significantly different from those in adjacent normal tissues tissue_expression_ns hsa-mir-155 Pancreatic Neoplasms 26499892 "We found miR-21, miR-155 or miR-217 expression values in tumors may differ up to several times" tissue_expression_ns hsa-mir-196a Pancreatic Neoplasms 26499892 "Moreover, different internal controls can produce controversial results for miR-96, miR-148a or miR-196a quantification." tissue_expression_ns hsa-mir-200b Hypertrophic Scar 26500110 Aberrant miR-21 and miR-200b expression and its pro-fibrotic potential in hypertrophic scars. tissue_expression_ns hsa-mir-21 Hypertrophic Scar 26500110 Aberrant miR-21 and miR-200b expression and its pro-fibrotic potential in hypertrophic scars. tissue_expression_ns hsa-mir-199a Diabetic Cardiomyopathies 26553540 A dysregulation of 316 out of 1008 total miRNAs was observed in the diabetic hearts when compared with controls. tissue_expression_ns hsa-mir-203 Psoriasis 26559308 "Key roles of several unique miRNAs, such as miR-203 and miR-125b, in inflammatory responses and immune dysfunction, as well as hyperproliferative disorders of psoriatic lesions have been revealed." tissue_expression_ns hsa-mir-192 Barrett Esophagus 26572780 "MicroRNAs miR-192, -194, -203, -205, and -215 are promising tissue biomarkers for diagnosing BE. Cross-sectional data suggest that microRNAs may have a limited role in separating BE from HGD/EAC epithelia but need further testing in longitudinal follow-up studies." tissue_expression_ns hsa-mir-194 Barrett Esophagus 26572780 "MicroRNAs miR-192, -194, -203, -205, and -215 are promising tissue biomarkers for diagnosing BE. Cross-sectional data suggest that microRNAs may have a limited role in separating BE from HGD/EAC epithelia but need further testing in longitudinal follow-up studies." tissue_expression_ns hsa-mir-203 Barrett Esophagus 26572780 "MicroRNAs miR-192, -194, -203, -205, and -215 are promising tissue biomarkers for diagnosing BE. Cross-sectional data suggest that microRNAs may have a limited role in separating BE from HGD/EAC epithelia but need further testing in longitudinal follow-up studies." tissue_expression_ns hsa-mir-205 Barrett Esophagus 26572780 "MicroRNAs miR-192, -194, -203, -205, and -215 are promising tissue biomarkers for diagnosing BE. Cross-sectional data suggest that microRNAs may have a limited role in separating BE from HGD/EAC epithelia but need further testing in longitudinal follow-up studies." tissue_expression_ns hsa-mir-215 Barrett Esophagus 26572780 "MicroRNAs miR-192, -194, -203, -205, and -215 are promising tissue biomarkers for diagnosing BE. Cross-sectional data suggest that microRNAs may have a limited role in separating BE from HGD/EAC epithelia but need further testing in longitudinal follow-up studies." tissue_expression_ns hsa-mir-7 Schizophrenia 26572867 "Here we show post-transcriptional regulation of SHANK3 expression by three microRNAs (miRNAs), miR-7, miR-34a, and miR-504." tissue_expression_ns hsa-mir-126 Bladder Neoplasms 26576778 "MicroRNA profiling from matched samples in patients shows a significant number of microRNAs up regulated in bladder tumors are identifiable in urine exosomes and WBCs of the same patient, but not in blood plasma. This study demonstrated varying relationships between miRNA detected in biological media from the same patient, and serves to inform the potential of urine-based microRNAs as biomarkers for bladder cancer and potentially other malignancies." tissue_expression_ns hsa-mir-150 Bladder Neoplasms 26576778 "MicroRNA profiling from matched samples in patients shows a significant number of microRNAs up regulated in bladder tumors are identifiable in urine exosomes and WBCs of the same patient, but not in blood plasma. This study demonstrated varying relationships between miRNA detected in biological media from the same patient, and serves to inform the potential of urine-based microRNAs as biomarkers for bladder cancer and potentially other malignancies." tissue_expression_ns hsa-mir-15b Bladder Neoplasms 26576778 "MicroRNA profiling from matched samples in patients shows a significant number of microRNAs up regulated in bladder tumors are identifiable in urine exosomes and WBCs of the same patient, but not in blood plasma. This study demonstrated varying relationships between miRNA detected in biological media from the same patient, and serves to inform the potential of urine-based microRNAs as biomarkers for bladder cancer and potentially other malignancies." tissue_expression_ns hsa-mir-200c Bladder Neoplasms 26576778 "MicroRNA profiling from matched samples in patients shows a significant number of microRNAs up regulated in bladder tumors are identifiable in urine exosomes and WBCs of the same patient, but not in blood plasma. This study demonstrated varying relationships between miRNA detected in biological media from the same patient, and serves to inform the potential of urine-based microRNAs as biomarkers for bladder cancer and potentially other malignancies." tissue_expression_ns hsa-mir-205 Bladder Neoplasms 26576778 "MicroRNA profiling from matched samples in patients shows a significant number of microRNAs up regulated in bladder tumors are identifiable in urine exosomes and WBCs of the same patient, but not in blood plasma. This study demonstrated varying relationships between miRNA detected in biological media from the same patient, and serves to inform the potential of urine-based microRNAs as biomarkers for bladder cancer and potentially other malignancies." tissue_expression_ns hsa-mir-21 Bladder Neoplasms 26576778 "MicroRNA profiling from matched samples in patients shows a significant number of microRNAs up regulated in bladder tumors are identifiable in urine exosomes and WBCs of the same patient, but not in blood plasma. This study demonstrated varying relationships between miRNA detected in biological media from the same patient, and serves to inform the potential of urine-based microRNAs as biomarkers for bladder cancer and potentially other malignancies." tissue_expression_ns hsa-mir-29b Bladder Neoplasms 26576778 "MicroRNA profiling from matched samples in patients shows a significant number of microRNAs up regulated in bladder tumors are identifiable in urine exosomes and WBCs of the same patient, but not in blood plasma. This study demonstrated varying relationships between miRNA detected in biological media from the same patient, and serves to inform the potential of urine-based microRNAs as biomarkers for bladder cancer and potentially other malignancies." tissue_expression_ns hsa-mir-3007a Bladder Neoplasms 26576778 "MicroRNA profiling from matched samples in patients shows a significant number of microRNAs up regulated in bladder tumors are identifiable in urine exosomes and WBCs of the same patient, but not in blood plasma. This study demonstrated varying relationships between miRNA detected in biological media from the same patient, and serves to inform the potential of urine-based microRNAs as biomarkers for bladder cancer and potentially other malignancies." tissue_expression_ns hsa-mir-4454 Bladder Neoplasms 26576778 "MicroRNA profiling from matched samples in patients shows a significant number of microRNAs up regulated in bladder tumors are identifiable in urine exosomes and WBCs of the same patient, but not in blood plasma. This study demonstrated varying relationships between miRNA detected in biological media from the same patient, and serves to inform the potential of urine-based microRNAs as biomarkers for bladder cancer and potentially other malignancies." tissue_expression_ns hsa-mir-720 Bladder Neoplasms 26576778 "MicroRNA profiling from matched samples in patients shows a significant number of microRNAs up regulated in bladder tumors are identifiable in urine exosomes and WBCs of the same patient, but not in blood plasma. This study demonstrated varying relationships between miRNA detected in biological media from the same patient, and serves to inform the potential of urine-based microRNAs as biomarkers for bladder cancer and potentially other malignancies." tissue_expression_ns hsa-mir-93 Bladder Neoplasms 26576778 "MicroRNA profiling from matched samples in patients shows a significant number of microRNAs up regulated in bladder tumors are identifiable in urine exosomes and WBCs of the same patient, but not in blood plasma. This study demonstrated varying relationships between miRNA detected in biological media from the same patient, and serves to inform the potential of urine-based microRNAs as biomarkers for bladder cancer and potentially other malignancies." tissue_expression_ns hsa-mir-194 Choriocarcinoma 26578390 "we found hsa-miR-194 and hsa-miR-7 along with 7 transcription factors (TFs) such as SOX11, SMAD3 and SOX4 etc. could correctly differentiate SPN from PanNET" tissue_expression_ns hsa-mir-204 Choriocarcinoma 26578390 "while hsa-miR-204 and 4 TFs such as SOX9, TCF7 and PPARD etc. were demonstrated as the potential markers for SPN versus PDAC." tissue_expression_ns hsa-mir-7 Neoplasms [unspecific] 26578390 "we found hsa-miR-194 and hsa-miR-7 along with 7 transcription factors (TFs) such as SOX11, SMAD3 and SOX4 etc. could correctly differentiate SPN from PanNET" tissue_expression_ns hsa-mir-106b Hepatoblastoma 26613016 These datasets provide a global landscape of miRNA expression for a rare childhood cancer that has not previously been well characterised. These data could serve as a resource for future studies aiming to make comparisons of HB miRNA profiles and to document aberrant miRNA expression in this type of cancer. tissue_expression_ns hsa-mir-17 Hepatoblastoma 26613016 These datasets provide a global landscape of miRNA expression for a rare childhood cancer that has not previously been well characterised. These data could serve as a resource for future studies aiming to make comparisons of HB miRNA profiles and to document aberrant miRNA expression in this type of cancer. tissue_expression_ns hsa-mir-191 Hepatoblastoma 26613016 These datasets provide a global landscape of miRNA expression for a rare childhood cancer that has not previously been well characterised. These data could serve as a resource for future studies aiming to make comparisons of HB miRNA profiles and to document aberrant miRNA expression in this type of cancer. tissue_expression_ns hsa-mir-95 Hepatoblastoma 26613016 These datasets provide a global landscape of miRNA expression for a rare childhood cancer that has not previously been well characterised. These data could serve as a resource for future studies aiming to make comparisons of HB miRNA profiles and to document aberrant miRNA expression in this type of cancer. tissue_expression_ns hsa-mir-149 Glioma 26617839 "Our study thus demonstrates that miR-149 expression in glioma tissues is critically associated with the prognosis of patients,suggesting its potential clinical significance." tissue_expression_ns hsa-mir-155 Stroke 26663183 "we will provide insight into recent knowledge from animal and human studies concerning miRNA profiling in acute stroke and their expression dynamics in brain tissue and extracellular fluids (roles of, e.g. let-7 family, miR-21, miR-29 family, miR-124, miR-145, miR-181 family, miR-210 and miR-223)" tissue_expression_ns hsa-mir-126 Ischemia 26672806 ghrelin treatment activated proangiogenic (miR-126 and miR-132) and antifibrotic (miR-30a) microRNAs (miRs) tissue_expression_ns hsa-mir-206 Ischemia 26672806 ghrelin treatment activated proangiogenic (miR-126 and miR-132) and antifibrotic (miR-30a) microRNAs (miRs) tissue_expression_ns hsa-mir-92a Ischemia 26672806 "Further, ghrelin treatment activated proangiogenic (miR-126 and miR-132) and antifibrotic (miR-30a) microRNAs (miRs) while inhibiting antiangiogenic (miR-92a and miR-206) miRs." tissue_expression_ns hsa-mir-375 Colorectal Carcinoma 26681654 "While the intra-tumor variance of miR-92a, miR-375 and miR-424 is substantial, it only constitutes approximately 30% of the total variation. Functional deregulation between tumor zones might contribute to variations in measured expression levels, and thus knowledge of specific intra-tumor expression patterns is crucial in tissue sampling for research as well as in future diagnostics." tissue_expression_ns hsa-mir-424 Colorectal Carcinoma 26681654 "While the intra-tumor variance of miR-92a, miR-375 and miR-424 is substantial, it only constitutes approximately 30% of the total variation. Functional deregulation between tumor zones might contribute to variations in measured expression levels, and thus knowledge of specific intra-tumor expression patterns is crucial in tissue sampling for research as well as in future diagnostics." tissue_expression_ns hsa-mir-92a Colorectal Carcinoma 26681654 "While the intra-tumor variance of miR-92a, miR-375 and miR-424 is substantial, it only constitutes approximately 30% of the total variation. Functional deregulation between tumor zones might contribute to variations in measured expression levels, and thus knowledge of specific intra-tumor expression patterns is crucial in tissue sampling for research as well as in future diagnostics." tissue_expression_ns hsa-mir-106b Breast Neoplasms 26684238 "Taken together, we have for the first time characterized the BMP4-induced miRNA expression profiles in breast cancer cell lines, showing that induced miRNAs contribute to the fine-tuning of proliferation and migration phenotypes." tissue_expression_ns hsa-mir-16 Breast Neoplasms 26684238 "Taken together, we have for the first time characterized the BMP4-induced miRNA expression profiles in breast cancer cell lines, showing that induced miRNAs contribute to the fine-tuning of proliferation and migration phenotypes." tissue_expression_ns hsa-mir-23a Breast Neoplasms 26684238 "Taken together, we have for the first time characterized the BMP4-induced miRNA expression profiles in breast cancer cell lines, showing that induced miRNAs contribute to the fine-tuning of proliferation and migration phenotypes." tissue_expression_ns hsa-mir-23b Breast Neoplasms 26684238 "Taken together, we have for the first time characterized the BMP4-induced miRNA expression profiles in breast cancer cell lines, showing that induced miRNAs contribute to the fine-tuning of proliferation and migration phenotypes." tissue_expression_ns hsa-mir-222 Pulmonary Sarcoidosis 26696750 "miRNAs in sarcoid BAL cells detected deregulation of miR-146a, miR-150, miR-202, miR-204, and miR-222 expression comparing to controls" tissue_expression_ns hsa-mir-1909 Neuroepithelial Tumors 26698155 "Our findings indicated that miR-3138 might act as a tumor suppressor gene when down-regulated and miR-1909* as a putative oncogenic molecule when up-regulated in pediatric DNETs compared to the control cohort. Subsequently, both miRNA signatures might serve as putative diagnostic biomarkers for pediatric DNETs." tissue_expression_ns hsa-mir-3138 Neuroepithelial Tumors 26698155 "Our findings indicated that miR-3138 might act as a tumor suppressor gene when down-regulated and miR-1909* as a putative oncogenic molecule when up-regulated in pediatric DNETs compared to the control cohort. Subsequently, both miRNA signatures might serve as putative diagnostic biomarkers for pediatric DNETs." tissue_expression_ns hsa-mir-100 Colorectal Carcinoma 26714601 "The expression of miR-100 is correlated with lymph node metastasis, TNM stage and differentiation grade, and may be a potential biomarker indicating the development of CRC." tissue_expression_ns hsa-mir-145 Lupus Nephritis 26722454 Association of miRNA-145 expression in vascular smooth muscle cells with vascular damages in patients with lupus nephritis. tissue_expression_ns hsa-mir-203 Diabetic Foot 26722550 "Our results demonstrated that expression profile of miR-203 in diabetic foot had a positive correlation with the severity of diabetic foot ulcers, which indicated that miR-203 can be served as a new, accurate and validated bio-marker for evaluating the severity of diabetic foot ulcers in clinic. The significant finding of the study: Quantification of miR-203 in different degrees of diabetic foot. This study adds a new bio-marker for evaluation and management of diabetic foot." tissue_expression_ns hsa-mir-182 "Carcinoma, Hepatocellular" 26728044 "In this study, fifteen microRNAs which were modulated in hepatic tissues and in tumors during the transition NAFLD-NASH-HCC are reported. Besides some already described, new and early dysregulated miRNAs were identified.Functional analyses are needed to validate the results here obtained, and to better define the role of these molecules in the progression of the hepatic disease." tissue_expression_ns hsa-mir-340 "Carcinoma, Hepatocellular" 26728044 "In this study, fifteen microRNAs which were modulated in hepatic tissues and in tumors during the transition NAFLD-NASH-HCC are reported. Besides some already described, new and early dysregulated miRNAs were identified.Functional analyses are needed to validate the results here obtained, and to better define the role of these molecules in the progression of the hepatic disease." tissue_expression_ns hsa-mir-484 "Carcinoma, Hepatocellular" 26728044 "In this study, fifteen microRNAs which were modulated in hepatic tissues and in tumors during the transition NAFLD-NASH-HCC are reported. Besides some already described, new and early dysregulated miRNAs were identified.Functional analyses are needed to validate the results here obtained, and to better define the role of these molecules in the progression of the hepatic disease." tissue_expression_ns hsa-mir-574 "Carcinoma, Hepatocellular" 26728044 "In this study, fifteen microRNAs which were modulated in hepatic tissues and in tumors during the transition NAFLD-NASH-HCC are reported. Besides some already described, new and early dysregulated miRNAs were identified.Functional analyses are needed to validate the results here obtained, and to better define the role of these molecules in the progression of the hepatic disease." tissue_expression_ns hsa-mir-720 "Carcinoma, Hepatocellular" 26728044 "In this study, fifteen microRNAs which were modulated in hepatic tissues and in tumors during the transition NAFLD-NASH-HCC are reported. Besides some already described, new and early dysregulated miRNAs were identified.Functional analyses are needed to validate the results here obtained, and to better define the role of these molecules in the progression of the hepatic disease." tissue_expression_ns hsa-mir-21 "Carcinoma, Renal Cell" 26729387 Diagnostic and prognostic accuracy of miR-21 in renal cell carcinoma: a systematic review protocol. tissue_expression_ns hsa-mir-1 Myocardial Ischemic-Reperfusion Injury 26738985 "Of the 17 miRs, 9 miRs, including miR-1, miR-21, miR-24, and miR-195, which are related to apoptosis, exhibited different expression patterns in the RIPerc group compared with the control." tissue_expression_ns hsa-mir-195 Myocardial Ischemic-Reperfusion Injury 26738985 "Of the 17 miRs, 9 miRs, including miR-1, miR-21, miR-24, and miR-195, which are related to apoptosis, exhibited different expression patterns in the RIPerc group compared with the control." tissue_expression_ns hsa-mir-200b Melanoma 26743475 "miR-10b and miR-200b showed independent prognostic value (P=0.002 and 0.047, respectively) in multivariable analysis alongside known clinico-pathological prognostic features" tissue_expression_ns hsa-mir-141 Prostate Neoplasms 26751899 miRNAs as novel biomarkers in the management of prostate cancer. tissue_expression_ns hsa-mir-21 Prostate Neoplasms 26751899 miRNAs as novel biomarkers in the management of prostate cancer. tissue_expression_ns hsa-mir-375 Prostate Neoplasms 26751899 miRNAs as novel biomarkers in the management of prostate cancer. tissue_expression_ns hsa-mir-146a Autism Spectrum Disorder 26753090 "We identified a signature of four miRNAs (miR-146a, miR-221, miR-654-5p, and miR-656) commonly deregulated in ASD." tissue_expression_ns hsa-mir-221 Autism Spectrum Disorder 26753090 "We identified a signature of four miRNAs (miR-146a, miR-221, miR-654-5p, and miR-656) commonly deregulated in ASD." tissue_expression_ns hsa-mir-125a Lupus Nephritis 26762103 "Levels of cell-free miR-125a, miR-150, and miR-155 in the urine supernatant are associated with the expression of LN-Panel biomarkers and some LN measures. These miRNA's may complement, but are unlikely superior to the LN-Panel for estimating concurrent LN activity." tissue_expression_ns hsa-mir-127 Lupus Nephritis 26762103 "Levels of cell-free miR-125a, miR-150, and miR-155 in the urine supernatant are associated with the expression of LN-Panel biomarkers and some LN measures. These miRNA's may complement, but are unlikely superior to the LN-Panel for estimating concurrent LN activity." tissue_expression_ns hsa-mir-146a Lupus Nephritis 26762103 "Levels of cell-free miR-125a, miR-150, and miR-155 in the urine supernatant are associated with the expression of LN-Panel biomarkers and some LN measures. These miRNA's may complement, but are unlikely superior to the LN-Panel for estimating concurrent LN activity." tissue_expression_ns hsa-mir-150 Lupus Nephritis 26762103 "Levels of cell-free miR-125a, miR-150, and miR-155 in the urine supernatant are associated with the expression of LN-Panel biomarkers and some LN measures. These miRNA's may complement, but are unlikely superior to the LN-Panel for estimating concurrent LN activity." tissue_expression_ns hsa-mir-155 Lupus Nephritis 26762103 "Levels of cell-free miR-125a, miR-150, and miR-155 in the urine supernatant are associated with the expression of LN-Panel biomarkers and some LN measures. These miRNA's may complement, but are unlikely superior to the LN-Panel for estimating concurrent LN activity." tissue_expression_ns hsa-mir-126 Mesothelioma 26765063 "Subject to validation of the current results in further larger studies, miR-21 and miR-126 profiling could be an effective and reliable tool for the diagnosis of MM in pleural effusions complementary to cytology evaluation." tissue_expression_ns hsa-mir-21 Mesothelioma 26765063 "Subject to validation of the current results in further larger studies, miR-21 and miR-126 profiling could be an effective and reliable tool for the diagnosis of MM in pleural effusions complementary to cytology evaluation." tissue_expression_ns hsa-let-7f Pulmonary Sarcoidosis 26768132 "The obtained results suggest that the studied miRNAs play a role in the pathogenesis of sarcoidosis, and that some of them might have negative prognostic value." tissue_expression_ns hsa-mir-128a Pulmonary Sarcoidosis 26768132 "The obtained results suggest that the studied miRNAs play a role in the pathogenesis of sarcoidosis, and that some of them might have negative prognostic value." tissue_expression_ns hsa-mir-130a Pulmonary Sarcoidosis 26768132 "The obtained results suggest that the studied miRNAs play a role in the pathogenesis of sarcoidosis, and that some of them might have negative prognostic value." tissue_expression_ns hsa-mir-15b Pulmonary Sarcoidosis 26768132 "The obtained results suggest that the studied miRNAs play a role in the pathogenesis of sarcoidosis, and that some of them might have negative prognostic value." tissue_expression_ns hsa-mir-16 Pulmonary Sarcoidosis 26768132 "The obtained results suggest that the studied miRNAs play a role in the pathogenesis of sarcoidosis, and that some of them might have negative prognostic value." tissue_expression_ns hsa-mir-192 Pulmonary Sarcoidosis 26768132 "The obtained results suggest that the studied miRNAs play a role in the pathogenesis of sarcoidosis, and that some of them might have negative prognostic value." tissue_expression_ns hsa-mir-20a Pulmonary Sarcoidosis 26768132 "The obtained results suggest that the studied miRNAs play a role in the pathogenesis of sarcoidosis, and that some of them might have negative prognostic value." tissue_expression_ns hsa-mir-221 Pulmonary Sarcoidosis 26768132 "The obtained results suggest that the studied miRNAs play a role in the pathogenesis of sarcoidosis, and that some of them might have negative prognostic value." tissue_expression_ns hsa-mir-222 Pulmonary Sarcoidosis 26768132 "The obtained results suggest that the studied miRNAs play a role in the pathogenesis of sarcoidosis, and that some of them might have negative prognostic value." tissue_expression_ns hsa-mir-1244 Gastric Cardia Adenocarcinoma 26781873 "Four miRNAs (miR-1244, miR-135b-5p, miR-3196, and miR-628-3p) were found to be associated with GCA differentiation." tissue_expression_ns hsa-mir-135b Gastric Cardia Adenocarcinoma 26781873 "Four miRNAs (miR-1244, miR-135b-5p, miR-3196, and miR-628-3p) were found to be associated with GCA differentiation." tissue_expression_ns hsa-mir-196a Gastric Cardia Adenocarcinoma 26781873 "miR-196a-5p, was found to be associated with age of GCA onset." tissue_expression_ns hsa-mir-3196 Gastric Cardia Adenocarcinoma 26781873 "Four miRNAs (miR-1244, miR-135b-5p, miR-3196, and miR-628-3p) were found to be associated with GCA differentiation." tissue_expression_ns hsa-mir-628 Gastric Cardia Adenocarcinoma 26781873 "Four miRNAs (miR-1244, miR-135b-5p, miR-3196, and miR-628-3p) were found to be associated with GCA differentiation." tissue_expression_ns hsa-mir-494 Pancreatic Neoplasms 26782462 Correlation of miR-494 expression with tumor progression and patient survival in pancreatic cancer. tissue_expression_ns hsa-mir-21 Glioma 26799295 "4 hypoxia-mediated microRNAs (miRNA)-miR-210, miR-21, miR-10b, and miR-196b-are upregulated in glioma" tissue_expression_ns hsa-mir-199a Melanoma 26812476 "Five miRNAs (miR-214, miR146b, miR-143, miR-199a and miR-134) were found to be differentially expressed in M3/ D3 UM tumors." tissue_expression_ns hsa-mir-146a Vogt-Koyanagi-Harada Disease 26818976 "CNVs of miR-146a, miR-23a and miR-301a confer susceptibility to VKH syndrome, but not to BD." tissue_expression_ns hsa-mir-1 Endometriosis 26819681 "The expression of miR-1, miR-133a, and miR-451 were reduced significantly (p<0.0001) in the OC patients compared to its associated endometriosis." tissue_expression_ns hsa-mir-141 Neoplasms [unspecific] 26828359 microRNA (miR)-141 is aberrantly expressed in many human malignant tumors tissue_expression_ns hsa-mir-223 Autoimmune Diseases [unspecific] 26879236 using co-expression analysis of miRNA expression levels we showed that multiple miRNA contribute to multiple pathways that might be involved in pathogenesis of autoimmune skin blistering disease. tissue_expression_ns hsa-mir-181c "Squamous Cell Carcinoma, Esophageal" 26888510 "There are significant correlation between miR-181c-3p/miR-5692b expression, clinicopathologic parameters and prognosis. They represent potential prognostic biomarkers in esophageal squamous cell carcinoma." tissue_expression_ns hsa-mir-5692b "Squamous Cell Carcinoma, Esophageal" 26888510 "There are significant correlation between miR-181c-3p/miR-5692b expression, clinicopathologic parameters and prognosis. They represent potential prognostic biomarkers in esophageal squamous cell carcinoma." tissue_expression_ns hsa-mir-21 Breast Neoplasms 26891730 Analysis has shown that changes in miR-21 levels might be important for the later and/or late phases of breast cancerogenesis rather than for the initial early phases. tissue_expression_ns hsa-mir-124a Breast Neoplasms 26897751 MiR-124a and miR-30d were correlated with insulin resistance and development of BC with T2DM. tissue_expression_ns hsa-mir-124a "Diabetes Mellitus, Type 2" 26897751 MiR-124a and miR-30d were correlated with insulin resistance and development of BC with T2DM. tissue_expression_ns hsa-mir-30d Breast Neoplasms 26897751 MiR-124a and miR-30d were correlated with insulin resistance and development of BC with T2DM. tissue_expression_ns hsa-mir-30d "Diabetes Mellitus, Type 2" 26897751 MiR-124a and miR-30d were correlated with insulin resistance and development of BC with T2DM. tissue_expression_ns hsa-mir-181c Silicosis 26903263 The differential expression of two selected miRNAs hsa-miR-181c-5p and hsa-miR-29a-3p were confirmed by RT-qPCR. tissue_expression_ns hsa-mir-29a Silicosis 26903263 The differential expression of two selected miRNAs hsa-miR-181c-5p and hsa-miR-29a-3p were confirmed by RT-qPCR. tissue_expression_ns hsa-mir-27a Colorectal Carcinoma 26913599 Low miR-27a-expressing cells displayed more ecto-calreticulin on the cell surface and increased ATP and HMGB1 secretion than high miR-27a-expressing ones in time-course experiments upon drug exposure. tissue_expression_ns hsa-mir-130b "Carcinoma, Hepatocellular" 26927562 The expression and clinopathological significance of miR-130b in human hepatocellular carcinoma tissue_expression_ns hsa-let-7g Rectal Neoplasms 26937645 "We recommend the mean expression of miR-27a, miR-193a-5p and let-7g as normalisation factor, when performing miRNA expression analyses by RT-qPCR on rectal cancer tissue." tissue_expression_ns hsa-mir-193a Rectal Neoplasms 26937645 "We recommend the mean expression of miR-27a, miR-193a-5p and let-7g as normalisation factor, when performing miRNA expression analyses by RT-qPCR on rectal cancer tissue." tissue_expression_ns hsa-mir-27a Rectal Neoplasms 26937645 "We recommend the mean expression of miR-27a, miR-193a-5p and let-7g as normalisation factor, when performing miRNA expression analyses by RT-qPCR on rectal cancer tissue." tissue_expression_ns hsa-mir-645 Rectal Neoplasms 26937645 "We recommend the mean expression of miR-27a, miR-193a-5p and let-7g as normalisation factor, when performing miRNA expression analyses by RT-qPCR on rectal cancer tissue." tissue_expression_ns hsa-let-7c Breast Neoplasms 26982264 "we identified seven miRNAs (miR-9-5p, miR-9-3p, let-7c, miR-127-3p, miR-99a-5p, miR-129-5p, and miR-146a-5p) that were deregulated as a consequence of claudin 1 overexpression in the MDA-MB231 human breast cancer (HBC) cell line." tissue_expression_ns hsa-mir-127 Breast Neoplasms 26982264 "we identified seven miRNAs (miR-9-5p, miR-9-3p, let-7c, miR-127-3p, miR-99a-5p, miR-129-5p, and miR-146a-5p) that were deregulated as a consequence of claudin 1 overexpression in the MDA-MB231 human breast cancer (HBC) cell line." tissue_expression_ns hsa-mir-129 Breast Neoplasms 26982264 "we identified seven miRNAs (miR-9-5p, miR-9-3p, let-7c, miR-127-3p, miR-99a-5p, miR-129-5p, and miR-146a-5p) that were deregulated as a consequence of claudin 1 overexpression in the MDA-MB231 human breast cancer (HBC) cell line." tissue_expression_ns hsa-mir-146a Breast Neoplasms 26982264 "we identified seven miRNAs (miR-9-5p, miR-9-3p, let-7c, miR-127-3p, miR-99a-5p, miR-129-5p, and miR-146a-5p) that were deregulated as a consequence of claudin 1 overexpression in the MDA-MB231 human breast cancer (HBC) cell line." tissue_expression_ns hsa-mir-9 Breast Neoplasms 26982264 "we identified seven miRNAs (miR-9-5p, miR-9-3p, let-7c, miR-127-3p, miR-99a-5p, miR-129-5p, and miR-146a-5p) that were deregulated as a consequence of claudin 1 overexpression in the MDA-MB231 human breast cancer (HBC) cell line." tissue_expression_ns hsa-mir-99a Breast Neoplasms 26982264 "we identified seven miRNAs (miR-9-5p, miR-9-3p, let-7c, miR-127-3p, miR-99a-5p, miR-129-5p, and miR-146a-5p) that were deregulated as a consequence of claudin 1 overexpression in the MDA-MB231 human breast cancer (HBC) cell line." tissue_expression_ns hsa-mir-199a "Carcinoma, Hepatocellular" 26998997 miTALOS v2: Analyzing Tissue Specific microRNA Function. tissue_expression_ns hsa-mir-199b "Carcinoma, Hepatocellular" 26998997 miTALOS v3: Analyzing Tissue Specific microRNA Function. tissue_expression_ns hsa-mir-200 "Carcinoma, Hepatocellular" 26998997 miTALOS v4: Analyzing Tissue Specific microRNA Function. tissue_expression_ns hsa-mir-571 "Carcinoma, Hepatocellular" 26998997 miTALOS v5: Analyzing Tissue Specific microRNA Function. tissue_expression_ns hsa-mir-223 Multiple Myeloma 27023728 miR-223 expression in MM-BMMSCs was reduced by the presence of MM cells tissue_expression_ns hsa-mir-126 Traumatic Brain Injury 27027233 Our results indicated that altered expression of miR-126-3p and miR-3610 may play an important role in the development of TBI-induced hypopituitarism. tissue_expression_ns hsa-mir-3610 Traumatic Brain Injury 27027233 Our results indicated that altered expression of miR-126-3p and miR-3610 may play an important role in the development of TBI-induced hypopituitarism. tissue_expression_ns hsa-mir-130a Cardiotoxicity 27033315 "We report on several microRNAs, including miR-34a, miR-34b, miR-187, miR-199a, miR-199b, miR-146a, miR-15b, miR-130a, miR-214, and miR-424, that are differentially expressed upon, and after, treatment with doxorubicin." tissue_expression_ns hsa-mir-146a Cardiotoxicity 27033315 "We report on several microRNAs, including miR-34a, miR-34b, miR-187, miR-199a, miR-199b, miR-146a, miR-15b, miR-130a, miR-214, and miR-424, that are differentially expressed upon, and after, treatment with doxorubicin." tissue_expression_ns hsa-mir-15b Cardiotoxicity 27033315 "We report on several microRNAs, including miR-34a, miR-34b, miR-187, miR-199a, miR-199b, miR-146a, miR-15b, miR-130a, miR-214, and miR-424, that are differentially expressed upon, and after, treatment with doxorubicin." tissue_expression_ns hsa-mir-187 Cardiotoxicity 27033315 "We report on several microRNAs, including miR-34a, miR-34b, miR-187, miR-199a, miR-199b, miR-146a, miR-15b, miR-130a, miR-214, and miR-424, that are differentially expressed upon, and after, treatment with doxorubicin." tissue_expression_ns hsa-mir-199a Cardiotoxicity 27033315 "We report on several microRNAs, including miR-34a, miR-34b, miR-187, miR-199a, miR-199b, miR-146a, miR-15b, miR-130a, miR-214, and miR-424, that are differentially expressed upon, and after, treatment with doxorubicin." tissue_expression_ns hsa-mir-199b Cardiotoxicity 27033315 "We report on several microRNAs, including miR-34a, miR-34b, miR-187, miR-199a, miR-199b, miR-146a, miR-15b, miR-130a, miR-214, and miR-424, that are differentially expressed upon, and after, treatment with doxorubicin." tissue_expression_ns hsa-mir-214 Cardiotoxicity 27033315 "We report on several microRNAs, including miR-34a, miR-34b, miR-187, miR-199a, miR-199b, miR-146a, miR-15b, miR-130a, miR-214, and miR-424, that are differentially expressed upon, and after, treatment with doxorubicin." tissue_expression_ns hsa-mir-34a Cardiotoxicity 27033315 "We report on several microRNAs, including miR-34a, miR-34b, miR-187, miR-199a, miR-199b, miR-146a, miR-15b, miR-130a, miR-214, and miR-424, that are differentially expressed upon, and after, treatment with doxorubicin." tissue_expression_ns hsa-mir-34b Cardiotoxicity 27033315 "We report on several microRNAs, including miR-34a, miR-34b, miR-187, miR-199a, miR-199b, miR-146a, miR-15b, miR-130a, miR-214, and miR-424, that are differentially expressed upon, and after, treatment with doxorubicin." tissue_expression_ns hsa-mir-424 Cardiotoxicity 27033315 "We report on several microRNAs, including miR-34a, miR-34b, miR-187, miR-199a, miR-199b, miR-146a, miR-15b, miR-130a, miR-214, and miR-424, that are differentially expressed upon, and after, treatment with doxorubicin." tissue_expression_ns hsa-mir-148a Osteosarcoma 27041566 we show that miR-148a-3p and miR-155-5p are species-conserved deregulated miRNA in OS tissue_expression_ns hsa-mir-155 Osteosarcoma 27041566 we show that miR-148a-3p and miR-155-5p are species-conserved deregulated miRNA in OS tissue_expression_ns hsa-let-7f Obesity 27049726 "Our study shows that the first evidence of hsa-let-7 family, hsa-miR-15a-5p, hsa-miR-27a-3p, hsa-miR-106b-5p, hsa-miR-148a-3p and hsa-miR-26b-5p got a great weight in adipogenesis" tissue_expression_ns hsa-mir-1275 "Squamous Cell Carcinoma, Oral" 27056547 "the expression of miR-1275 was variable in tumours, with high levels associated to regional lymph node invasion;" tissue_expression_ns hsa-mir-29a "Carcinoma, Ovarian, Serous" 27063471 "miR-29a and its target DNMT3A are novel candidate biomarkers of longer and shorter survival, respectively, in metastatic high-grade serous carcinoma." tissue_expression_ns hsa-mir-21 "Adenocarcinoma, Lung" 27081085 "We identified a regulatory network including miR-15b and miR-155, and transcription factors with prognostic value in lung cancer." tissue_expression_ns hsa-mir-139 Breast Neoplasms 27082076 miRNAs included in the invasive signatures include downregulation of miR-139-5p in aggressive subtypes and upregulation of miR-29c-5p expression in the luminal subtypes. tissue_expression_ns hsa-mir-29c Breast Neoplasms 27082076 include downregulation of miR-139-5p in aggressive subtypes and upregulation of miR-29c-5p expression in the luminal subtypes. tissue_expression_ns hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 27086919 We provide further evidence for using miRNAs as diagnostic biomarkers for pancreatic malignancy. tissue_expression_ns hsa-mir-196 Tuberculosis 27102525 9 miRNAs were differentially expressed after MAP infection. tissue_expression_ns hsa-mir-24 Cardiovascular Diseases [unspecific] 27108908 "The dysregulation of miR-24 is associated with dysfunction or even damage of VECs, and contributes to the development of cardiovascular disease." tissue_expression_ns hsa-mir-21 "Carcinoma, Breast, Triple Negative" 27113307 The function of MiR-21 expression differences and pathogenesis on familial and triple negative breast Cancer serum. tissue_expression_ns hsa-mir-223 Inflammation 27129807 "miR-223 that has been reported to be abnormally expressed in several diseases like diabetes-type2, sepsis, rheumatoid arthritis, viral infections likes' human immunodeficiency virus-1 (HIV-1) and inflammatory disorders." tissue_expression_ns hsa-mir-223 Sepsis 27129807 "miR-223 that has been reported to be abnormally expressed in several diseases like diabetes-type2, sepsis, rheumatoid arthritis, viral infections likes' human immunodeficiency virus-1 (HIV-1) and inflammatory disorders." tissue_expression_ns hsa-mir-200 Colorectal Carcinoma 27157610 "The miR-200 family presented as the most powerful determinant of CMS4-specific gene expression, tuning the majority of genes differentially expressed in the poor prognosis subtype," tissue_expression_ns hsa-mir-125b Oral Neoplasms 27208839 "Differential expression of miR-21, miR-100, miR-125b and miR-375 was validated in oral cytology training sample set." tissue_expression_ns hsa-mir-150 Bronchopulmonary Dysplasia 27216745 expression of miR-150 was altered in experimental BPD tissue_expression_ns hsa-mir-127 Balkan Nephropathy 27218105 " Only three microRNAs (hsa-miR-127-3p, hsa-miR-154-5p, and hsa-miR-30a-5p) were downregulated among BEN-UTUC, and one microRNA (hsa-miR-663b) was downregulated among non-BEN-UTUC samples" tissue_expression_ns hsa-mir-154 Balkan Nephropathy 27218105 " Only three microRNAs (hsa-miR-127-3p, hsa-miR-154-5p, and hsa-miR-30a-5p) were downregulated among BEN-UTUC, and one microRNA (hsa-miR-663b) was downregulated among non-BEN-UTUC samples" tissue_expression_ns hsa-mir-30a Balkan Nephropathy 27218105 " Only three microRNAs (hsa-miR-127-3p, hsa-miR-154-5p, and hsa-miR-30a-5p) were downregulated among BEN-UTUC, and one microRNA (hsa-miR-663b) was downregulated among non-BEN-UTUC samples" tissue_expression_ns hsa-mir-663b Balkan Nephropathy 27218105 " Only three microRNAs (hsa-miR-127-3p, hsa-miR-154-5p, and hsa-miR-30a-5p) were downregulated among BEN-UTUC, and one microRNA (hsa-miR-663b) was downregulated among non-BEN-UTUC samples" tissue_expression_ns hsa-mir-765 Soft Tissue Sarcoma 27223121 miR-765 could possibly be a diagnostic tool for ES because of its 97% specificity and 80% sensitivity. tissue_expression_ns hsa-mir-630 Rectum Adenocarcinoma 27225591 The miR-630 appeared only with the NR patients and was anti-correlated with a single transcript: RAB5B. tissue_expression_ns hsa-mir-138 Down Syndrome 27266699 The function of hsa-miR-138-5p and its target EZH2 was involved in hippocampus in DS patients. tissue_expression_ns hsa-mir-138 Chondrosarcoma 27267924 "increased expression of two microRNAs, miRs-181a and -138, in low-grade chondrosarcomas compared with enchondromas" tissue_expression_ns hsa-mir-126 "Adenocarcinoma, Lung" 27277197 "Low levels of miR-126-3p and miR-451a were associated with poor pathological stage, large tumor diameter and lymph node metastasis" tissue_expression_ns hsa-mir-451a "Adenocarcinoma, Lung" 27277197 "Low levels of miR-126-3p and miR-451a were associated with poor pathological stage, large tumor diameter and lymph node metastasis" tissue_expression_ns hsa-mir-155 Laryngeal Neoplasms 27292022 "miR-21, miR-155, miR-192, and miR-375 Deregulations Related to NF-kappaB Activation in Gastroduodenal Fluid-Induced Early Preneoplastic Lesions of Laryngeal Mucosa In Vivo." tissue_expression_ns hsa-mir-192 Laryngeal Neoplasms 27292022 "miR-21, miR-155, miR-192, and miR-375 Deregulations Related to NF-kappaB Activation in Gastroduodenal Fluid-Induced Early Preneoplastic Lesions of Laryngeal Mucosa In Vivo." tissue_expression_ns hsa-mir-21 Laryngeal Neoplasms 27292022 "miR-21, miR-155, miR-192, and miR-375 Deregulations Related to NF-kappaB Activation in Gastroduodenal Fluid-Induced Early Preneoplastic Lesions of Laryngeal Mucosa In Vivo." tissue_expression_ns hsa-mir-375 Laryngeal Neoplasms 27292022 "miR-21, miR-155, miR-192, and miR-375 Deregulations Related to NF-kappaB Activation in Gastroduodenal Fluid-Induced Early Preneoplastic Lesions of Laryngeal Mucosa In Vivo." tissue_expression_ns hsa-mir-26a Multiple Sclerosis 27310932 down-regulation of miR-155 and miR-26a was seen in MS patients during and after natalizumab therapy. tissue_expression_ns hsa-mir-146a Melanoma 27311960 "miR-146a controls melanoma progression in a dual way, promoting growth and inhibiting dissemination" tissue_expression_ns hsa-mir-130a "Carcinoma, Nasopharyngeal" 27350400 "hsa-miR-205, hsa-miR-18b, hsa-miR-632, hsa-miR-130a, and hsa-miR-34b may be related to the development of nasopharyngeal carcinoma" tissue_expression_ns hsa-mir-18b "Carcinoma, Nasopharyngeal" 27350400 "hsa-miR-205, hsa-miR-18b, hsa-miR-632, hsa-miR-130a, and hsa-miR-34b may be related to the development of nasopharyngeal carcinoma" tissue_expression_ns hsa-mir-205 "Carcinoma, Nasopharyngeal" 27350400 "hsa-miR-205, hsa-miR-18b, hsa-miR-632, hsa-miR-130a, and hsa-miR-34b may be related to the development of nasopharyngeal carcinoma" tissue_expression_ns hsa-mir-34b "Carcinoma, Nasopharyngeal" 27350400 "hsa-miR-205, hsa-miR-18b, hsa-miR-632, hsa-miR-130a, and hsa-miR-34b may be related to the development of nasopharyngeal carcinoma" tissue_expression_ns hsa-mir-632 "Carcinoma, Nasopharyngeal" 27350400 "hsa-miR-205, hsa-miR-18b, hsa-miR-632, hsa-miR-130a, and hsa-miR-34b may be related to the development of nasopharyngeal carcinoma" tissue_expression_ns hsa-mir-141 Bladder Neoplasms 27357429 two types of cancer showed opposite expression patterns for miR-200 family miRNAs tissue_expression_ns hsa-mir-141 "Carcinoma, Renal Cell" 27357429 two types of cancer showed opposite expression patterns for miR-200 family miRNAs tissue_expression_ns hsa-mir-200 Bladder Neoplasms 27357429 two types of cancer showed opposite expression patterns for miR-200 family miRNAs tissue_expression_ns hsa-mir-200 "Carcinoma, Renal Cell" 27357429 two types of cancer showed opposite expression patterns for miR-200 family miRNAs tissue_expression_ns hsa-mir-200a Bladder Neoplasms 27357429 two types of cancer showed opposite expression patterns for miR-200 family miRNAs tissue_expression_ns hsa-mir-200a "Carcinoma, Renal Cell" 27357429 two types of cancer showed opposite expression patterns for miR-200 family miRNAs tissue_expression_ns hsa-mir-200b Bladder Neoplasms 27357429 two types of cancer showed opposite expression patterns for miR-200 family miRNAs tissue_expression_ns hsa-mir-200b "Carcinoma, Renal Cell" 27357429 two types of cancer showed opposite expression patterns for miR-200 family miRNAs tissue_expression_ns hsa-mir-200c Bladder Neoplasms 27357429 two types of cancer showed opposite expression patterns for miR-200 family miRNAs tissue_expression_ns hsa-mir-200c "Carcinoma, Renal Cell" 27357429 two types of cancer showed opposite expression patterns for miR-200 family miRNAs tissue_expression_ns hsa-mir-148a Neoplasms [unspecific] 27390598 Mir-148a is aberrantly expressed in various cancers and has been identified as an oncogenic or tumor suppressor with crucial roles in the molecular mechanisms of oncogenesis. tissue_expression_ns hsa-let-7 "Adenocarcinoma, Gastric" 27422560 The integrated analysis of miRNA and gene expression profiles showed the let-7 miRNA family playing a central role in the regulatory relationships. tissue_expression_ns hsa-let-7c "Adenocarcinoma, Gastric" 27422560 "The miRNAs 100, let-7c, 125b and 99a stood out for their association with the diffuse histological subtype." tissue_expression_ns hsa-mir-10a Breast Neoplasms 27433802 "We identified eight microRNAs (miR-10a, miR-10b, miR-21, miR-124, miR-125b, miR-126, miR-145 and miR-200a) to be associated with DMBA-induced mammary tumor progression." tissue_expression_ns hsa-mir-10b Breast Neoplasms 27433802 "We identified eight microRNAs (miR-10a, miR-10b, miR-21, miR-124, miR-125b, miR-126, miR-145 and miR-200a) to be associated with DMBA-induced mammary tumor progression." tissue_expression_ns hsa-mir-124 Breast Neoplasms 27433802 "We identified eight microRNAs (miR-10a, miR-10b, miR-21, miR-124, miR-125b, miR-126, miR-145 and miR-200a) to be associated with DMBA-induced mammary tumor progression." tissue_expression_ns hsa-mir-125b Breast Neoplasms 27433802 "We identified eight microRNAs (miR-10a, miR-10b, miR-21, miR-124, miR-125b, miR-126, miR-145 and miR-200a) to be associated with DMBA-induced mammary tumor progression." tissue_expression_ns hsa-mir-126 Breast Neoplasms 27433802 "We identified eight microRNAs (miR-10a, miR-10b, miR-21, miR-124, miR-125b, miR-126, miR-145 and miR-200a) to be associated with DMBA-induced mammary tumor progression." tissue_expression_ns hsa-mir-145 Breast Neoplasms 27433802 "We identified eight microRNAs (miR-10a, miR-10b, miR-21, miR-124, miR-125b, miR-126, miR-145 and miR-200a) to be associated with DMBA-induced mammary tumor progression." tissue_expression_ns hsa-mir-21 Breast Neoplasms 27433802 "We identified eight microRNAs (miR-10a, miR-10b, miR-21, miR-124, miR-125b, miR-126, miR-145 and miR-200a) to be associated with DMBA-induced mammary tumor progression." tissue_expression_ns hsa-mir-375 "Squamous Cell Carcinoma, Head and Neck" 27440205 Primary HNSCC carcinoma tissues can be distinguished from histologically normal-matched noncancerous tumour-adjacent tissues based on hsa-miR-375-3p expression. tissue_expression_ns hsa-mir-210 Bladder Neoplasms 27441495 "High miR-210 may reflect hypoxia in bladder cancer. However, its ability to predict benefit from hypoxia modification does not improve upon other hypoxia markers. Investigation as part of a miRNA hypoxia signature may reveal the full potential of miR-210." tissue_expression_ns hsa-mir-212 Schizophrenia 27468165 "miR-132, miR-133a and miR-212 were initially identified as differentially expressed in BP, miR-184 in MDD and miR-34a in both MDD and BP (although none survived multiple correction testing and must be considered preliminary)." tissue_expression_ns hsa-mir-200c Melanoma 27469124 miR expression profiles can be measured in indeterminate Spitz tumors and correlate with markers of malignant potential. tissue_expression_ns hsa-mir-221 Breast Neoplasms 27488105 "An increase in miR-221/222 might be an important event for in situ carcinoma formation, and miR-221/222 may be important molecules that highlight potential differences between invasive breast carcinomas associated with non-invasive and pure invasive BCs." tissue_expression_ns hsa-mir-222 Breast Neoplasms 27488105 "An increase in miR-221/222 might be an important event for in situ carcinoma formation, and miR-221/222 may be important molecules that highlight potential differences between invasive breast carcinomas associated with non-invasive and pure invasive BCs." tissue_expression_ns hsa-mir-138 "Carcinoma, Thyroid, Follicular" 27547222 Expression of miRNA and Occurrence of Distant Metastases in Patients with H¨¹rthle Cell Carcinoma. tissue_expression_ns hsa-mir-1285 "Carcinoma, Hepatocellular" 27554417 Diagnosis of HCC for patients with cirrhosis using miRNA profiles of the tumor-surrounding tissue - A statistical model based on stepwise penalized logistic regression. tissue_expression_ns hsa-mir-943 "Carcinoma, Hepatocellular" 27554417 Diagnosis of HCC for patients with cirrhosis using miRNA profiles of the tumor-surrounding tissue - A statistical model based on stepwise penalized logistic regression. tissue_expression_ns hsa-let-7b Crohn Disease 27556489 Mucosal MicroRNAs Expression Profiles before and after Exclusive Enteral Nutrition Therapy in Adult Patients with Crohn's Disease. tissue_expression_ns hsa-mir-124 Crohn Disease 27556489 Mucosal MicroRNAs Expression Profiles before and after Exclusive Enteral Nutrition Therapy in Adult Patients with Crohn's Disease. tissue_expression_ns hsa-mir-192 Crohn Disease 27556489 Mucosal MicroRNAs Expression Profiles before and after Exclusive Enteral Nutrition Therapy in Adult Patients with Crohn's Disease. tissue_expression_ns hsa-mir-301a Crohn Disease 27556489 Mucosal MicroRNAs Expression Profiles before and after Exclusive Enteral Nutrition Therapy in Adult Patients with Crohn's Disease. tissue_expression_ns hsa-mir-423 Crohn Disease 27556489 Mucosal MicroRNAs Expression Profiles before and after Exclusive Enteral Nutrition Therapy in Adult Patients with Crohn's Disease. tissue_expression_ns hsa-mir-495 Crohn Disease 27556489 Mucosal MicroRNAs Expression Profiles before and after Exclusive Enteral Nutrition Therapy in Adult Patients with Crohn's Disease. tissue_expression_ns hsa-mir-99a Crohn Disease 27556489 Mucosal MicroRNAs Expression Profiles before and after Exclusive Enteral Nutrition Therapy in Adult Patients with Crohn's Disease. tissue_expression_ns hsa-mir-146a Psoriasis 27562321 MicroRNA-146a and miR-99a are potential biomarkers for disease activity and clinical efficacy assessment in psoriasis patients treated with traditional Chinese medicine. tissue_expression_ns hsa-mir-99a Psoriasis 27562321 MicroRNA-146a and miR-99a are potential biomarkers for disease activity and clinical efficacy assessment in psoriasis patients treated with traditional Chinese medicine. tissue_expression_ns hsa-mir-146a Uveal Melanoma 27565163 Expression of natural killer cell regulatory microRNA by uveal melanoma cancer stem cells. tissue_expression_ns hsa-mir-155 Melanoma 27565163 Expression of natural killer cell regulatory microRNA by uveal melanoma cancer stem cells. tissue_expression_ns hsa-mir-200c Colorectal Carcinoma 27565378 "Investigating intra-tumor heterogeneity and expression gradients of miR-21, miR-92a and miR-200c and their potential of predicting lymph node metastases in early colorectal cancer." tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 27565378 "Investigating intra-tumor heterogeneity and expression gradients of miR-21, miR-92a and miR-200c and their potential of predicting lymph node metastases in early colorectal cancer." tissue_expression_ns hsa-mir-92a Colorectal Carcinoma 27565378 "Investigating intra-tumor heterogeneity and expression gradients of miR-21, miR-92a and miR-200c and their potential of predicting lymph node metastases in early colorectal cancer." tissue_expression_ns hsa-mir-574 "Squamous Cell Carcinoma, Esophageal" 27565418 The expression of microRNA 574-3p as a predictor of postoperative outcome in patients with esophageal squamous cell carcinoma. tissue_expression_ns hsa-mir-125b Melanoma 27566021 MicroRNA dysregulation in melanoma. tissue_expression_ns hsa-mir-150 Melanoma 27566021 MicroRNA dysregulation in melanoma. tissue_expression_ns hsa-mir-155 Melanoma 27566021 MicroRNA dysregulation in melanoma. tissue_expression_ns hsa-mir-205 Melanoma 27566021 MicroRNA dysregulation in melanoma. tissue_expression_ns hsa-mir-21 Melanoma 27566021 MicroRNA dysregulation in melanoma. tissue_expression_ns hsa-mir-211 Melanoma 27566021 MicroRNA dysregulation in melanoma. tissue_expression_ns hsa-mir-1247 Glioblastoma 27572852 "Several crucial genes, TFs, miRNAs and small molecules in the different GBM subgroups were identified, which may be used as potential markers" tissue_expression_ns hsa-mir-147b Glioblastoma 27572852 "Several crucial genes, TFs, miRNAs and small molecules in the different GBM subgroups were identified, which may be used as potential markers" tissue_expression_ns hsa-mir-220a Glioblastoma 27572852 "miR-147b, miR-770-5p, miR-220a and miR-1247 were the particular miRNAs in subgroups?1-4" tissue_expression_ns hsa-mir-770 Glioblastoma 27572852 "Several crucial genes, TFs, miRNAs and small molecules in the different GBM subgroups were identified, which may be used as potential markers" tissue_expression_ns hsa-mir-146b Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-193a Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-194 Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-1972 Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-200b Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-21 Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-29b Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-301a Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-3138 Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-34a Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-3663 Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-505 Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-513a Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-516a Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-575 Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-630 Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-636 Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-718 Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-99b Aortic Stenosis 27579316 MicroRNA Expression Signature in Degenerative Aortic Stenosis. tissue_expression_ns hsa-mir-100 "Carcinoma, Bladder" 27586262 microRNA expression profiles as decision-making biomarkers in the management of bladder cancer. tissue_expression_ns hsa-mir-146b "Carcinoma, Bladder" 27586262 microRNA expression profiles as decision-making biomarkers in the management of bladder cancer. tissue_expression_ns hsa-mir-193a "Carcinoma, Bladder" 27586262 microRNA expression profiles as decision-making biomarkers in the management of bladder cancer. tissue_expression_ns hsa-mir-34 "Carcinoma, Bladder" 27586262 microRNA expression profiles as decision-making biomarkers in the management of bladder cancer. tissue_expression_ns hsa-mir-9 "Carcinoma, Bladder" 27586262 microRNA expression profiles as decision-making biomarkers in the management of bladder cancer. tissue_expression_ns hsa-mir-92b "Carcinoma, Rectal" 27601590 Genome-Wide miRNA Analysis Identifies miR-188-3p as a Novel Prognostic Marker and Molecular Factor Involved in Colorectal Carcinogenesis. tissue_expression_ns hsa-mir-33b "Squamous Cell Carcinoma, Esophageal" 27609581 The expression and significance of miR-33b and HMGA2 in esophageal squamous cell carcinoma. tissue_expression_ns hsa-let-7a Neoplasms [unspecific] 27623940 Aberrant microRNA expression in tumor mycosis fungoides. tissue_expression_ns hsa-mir-1267 Neoplasms [unspecific] 27623940 Aberrant microRNA expression in tumor mycosis fungoides. tissue_expression_ns hsa-mir-1282 Neoplasms [unspecific] 27623940 Aberrant microRNA expression in tumor mycosis fungoides. tissue_expression_ns hsa-mir-200c Neoplasms [unspecific] 27623940 Aberrant microRNA expression in tumor mycosis fungoides. tissue_expression_ns hsa-mir-210 Neoplasms [unspecific] 27623940 Aberrant microRNA expression in tumor mycosis fungoides. tissue_expression_ns hsa-mir-29a Neoplasms [unspecific] 27623940 Aberrant microRNA expression in tumor mycosis fungoides. tissue_expression_ns hsa-mir-3177 Neoplasms [unspecific] 27623940 Aberrant microRNA expression in tumor mycosis fungoides. tissue_expression_ns hsa-mir-34a Neoplasms [unspecific] 27623940 Aberrant microRNA expression in tumor mycosis fungoides. tissue_expression_ns hsa-mir-514b Neoplasms [unspecific] 27623940 Aberrant microRNA expression in tumor mycosis fungoides. tissue_expression_ns hsa-mir-221 "Carcinoma, Prostate" 27630329 "to evaluate miR-23b, miR-26a and miR-221 expression levels in combination with preoperative serum PSA level to the risk of PCa recurrence after radical prostatectomy" tissue_expression_ns hsa-mir-23b "Carcinoma, Prostate" 27630329 "to evaluate miR-23b, miR-26a and miR-221 expression levels in combination with preoperative serum PSA level to the risk of PCa recurrence after radical prostatectomy" tissue_expression_ns hsa-mir-26a "Carcinoma, Prostate" 27630329 "to evaluate miR-23b, miR-26a and miR-221 expression levels in combination with preoperative serum PSA level to the risk of PCa recurrence after radical prostatectomy" tissue_expression_ns hsa-mir-100 "Carcinoma, Bladder" 27631180 Evaluation of miR-182/miR-100 Ratio for Diagnosis and Survival Prediction in Bladder Cancer. tissue_expression_ns hsa-mir-182 "Carcinoma, Bladder" 27631180 Evaluation of miR-182/miR-100 Ratio for Diagnosis and Survival Prediction in Bladder Cancer. tissue_expression_ns hsa-mir-143 Atherosclerosis 27631489 Differential Expression of MicroRNAs in Endarterectomy Specimens Taken from Patients with Asymptomatic and Symptomatic Carotid Plaques. tissue_expression_ns hsa-mir-21 Atherosclerosis 27631489 Differential Expression of MicroRNAs in Endarterectomy Specimens Taken from Patients with Asymptomatic and Symptomatic Carotid Plaques. tissue_expression_ns hsa-mir-195 Muscular Dystrophy 27651778 "At the epigenetic level, miRNAs are thought to be highly involved in the pathophysiological progress of denervated muscles" tissue_expression_ns hsa-mir-214 Muscular Dystrophy 27651778 "At the epigenetic level, miRNAs are thought to be highly involved in the pathophysiological progress of denervated muscles" tissue_expression_ns hsa-mir-221 Muscular Dystrophy 27651778 "At the epigenetic level, miRNAs are thought to be highly involved in the pathophysiological progress of denervated muscles" tissue_expression_ns hsa-mir-222 Muscular Dystrophy 27651778 "At the epigenetic level, miRNAs are thought to be highly involved in the pathophysiological progress of denervated muscles" tissue_expression_ns hsa-mir-320 Muscular Dystrophy 27651778 "At the epigenetic level, miRNAs are thought to be highly involved in the pathophysiological progress of denervated muscles" tissue_expression_ns hsa-mir-222 Breast Neoplasms 27659519 Profiles of miRNAs matched to biology in aromatase inhibitor resistant breast cancer. tissue_expression_ns hsa-mir-31 Breast Neoplasms 27659519 Profiles of miRNAs matched to biology in aromatase inhibitor resistant breast cancer. tissue_expression_ns hsa-mir-126 "Carcinoma, Lung, Non-Small-Cell" 27665734 Matrine induces cell cycle arrest and apoptosis with recovery of the expression of miR-126 in the A549 non-small cell lung cancer cell line. tissue_expression_ns hsa-mir-151a "Carcinoma, Thyroid, Medullary" 27666315 Selection and validation of miRNAs as normalizers for profiling expression of microRNAs isolated from thyroid fine needle aspiration smears. tissue_expression_ns hsa-mir-197 "Carcinoma, Thyroid, Medullary" 27666315 Selection and validation of miRNAs as normalizers for profiling expression of microRNAs isolated from thyroid fine needle aspiration smears. tissue_expression_ns hsa-mir-214 "Carcinoma, Thyroid, Medullary" 27666315 Selection and validation of miRNAs as normalizers for profiling expression of microRNAs isolated from thyroid fine needle aspiration smears. tissue_expression_ns hsa-mir-99a "Carcinoma, Thyroid, Medullary" 27666315 Selection and validation of miRNAs as normalizers for profiling expression of microRNAs isolated from thyroid fine needle aspiration smears. tissue_expression_ns hsa-mir-27a Down Syndrome 27666924 Integrated microRNA and protein expression analysis reveals novel microRNA regulation of targets in fetal down syndrome. tissue_expression_ns hsa-mir-27b Down Syndrome 27666924 Integrated microRNA and protein expression analysis reveals novel microRNA regulation of targets in fetal down syndrome. tissue_expression_ns hsa-mir-329 Down Syndrome 27666924 Integrated microRNA and protein expression analysis reveals novel microRNA regulation of targets in fetal down syndrome. tissue_expression_ns hsa-mir-135b Colorectal Carcinoma 27672263 "MicroRNA biomarkers predicting risk, initiation and progression of colorectal cancer." tissue_expression_ns hsa-mir-18a Colorectal Carcinoma 27672263 "MicroRNA biomarkers predicting risk, initiation and progression of colorectal cancer." tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 27672263 "MicroRNA biomarkers predicting risk, initiation and progression of colorectal cancer." tissue_expression_ns hsa-mir-601 Colorectal Carcinoma 27672263 "MicroRNA biomarkers predicting risk, initiation and progression of colorectal cancer." tissue_expression_ns hsa-mir-760 Colorectal Carcinoma 27672263 "MicroRNA biomarkers predicting risk, initiation and progression of colorectal cancer." tissue_expression_ns hsa-mir-92a Colorectal Carcinoma 27672263 "MicroRNA biomarkers predicting risk, initiation and progression of colorectal cancer." tissue_expression_ns hsa-mir-155 Liver Injury 27673475 Fine-tuning the expression of microRNA-155 controls acetaminophen-induced liver inflammation. tissue_expression_ns hsa-mir-122 "Diabetes Mellitus, Type 2" 27681254 Differentially expressed microRNAs in the corpus cavernosum from a murine model with type 2 diabetes mellitus-associated erectile dysfunction. tissue_expression_ns hsa-mir-133 "Diabetes Mellitus, Type 2" 27681254 Differentially expressed microRNAs in the corpus cavernosum from a murine model with type 2 diabetes mellitus-associated erectile dysfunction. tissue_expression_ns hsa-mir-18a "Diabetes Mellitus, Type 2" 27681254 Differentially expressed microRNAs in the corpus cavernosum from a murine model with type 2 diabetes mellitus-associated erectile dysfunction. tissue_expression_ns hsa-mir-206 "Diabetes Mellitus, Type 2" 27681254 Differentially expressed microRNAs in the corpus cavernosum from a murine model with type 2 diabetes mellitus-associated erectile dysfunction. tissue_expression_ns hsa-mir-10b Obesity 27682205 Impact of endurance exercise training on adipocyte microRNA expression in overweight men. tissue_expression_ns hsa-mir-204 Obesity 27682205 Impact of endurance exercise training on adipocyte microRNA expression in overweight men. tissue_expression_ns hsa-mir-3613 Obesity 27682205 Impact of endurance exercise training on adipocyte microRNA expression in overweight men. tissue_expression_ns hsa-mir-4532 Obesity 27682205 Impact of endurance exercise training on adipocyte microRNA expression in overweight men. tissue_expression_ns hsa-mir-155 "Carcinoma, Lung, Small-Cell" 27682492 Changes of microRNAs profiling in mesothelial cells exposed to multi-walled carbon nanotubes. tissue_expression_ns hsa-mir-28 "Carcinoma, Lung, Small-Cell" 27682492 Changes of microRNAs profiling in mesothelial cells exposed to multi-walled carbon nanotubes. tissue_expression_ns hsa-mir-30 "Carcinoma, Lung, Small-Cell" 27682492 Changes of microRNAs profiling in mesothelial cells exposed to multi-walled carbon nanotubes. tissue_expression_ns hsa-mir-324 "Carcinoma, Lung, Small-Cell" 27682492 Changes of microRNAs profiling in mesothelial cells exposed to multi-walled carbon nanotubes. tissue_expression_ns hsa-mir-34c "Carcinoma, Lung, Small-Cell" 27682492 Changes of microRNAs profiling in mesothelial cells exposed to multi-walled carbon nanotubes. tissue_expression_ns hsa-mir-18a Lung Fibrosis 27689473 Altered microRNA expression profiles in lung damage induced by nanosized SiO2. tissue_expression_ns hsa-mir-212 Lung Fibrosis 27689473 Altered microRNA expression profiles in lung damage induced by nanosized SiO2. tissue_expression_ns hsa-mir-128a Mesial Temporal Lobe Epilepsy 27695061 Identification of microRNAs with Dysregulated Expression in Status Epilepticus Induced Epileptogenesis. tissue_expression_ns hsa-mir-196b Mesial Temporal Lobe Epilepsy 27695061 Identification of microRNAs with Dysregulated Expression in Status Epilepticus Induced Epileptogenesis. tissue_expression_ns hsa-mir-352 Mesial Temporal Lobe Epilepsy 27695061 Identification of microRNAs with Dysregulated Expression in Status Epilepticus Induced Epileptogenesis. tissue_expression_ns hsa-mir-31 "Adenocarcinoma, Lung" 27695346 MicroRNA expression profiles predict progression and clinical outcome in lung adenocarcinoma. tissue_expression_ns hsa-mir-1238 Chronic Brucellosis 27722176 "Altered Expressions of miR-1238-3p, miR-494, miR-6069, and miR-139-3p in the Formation of Chronic Brucellosis." tissue_expression_ns hsa-mir-139 Chronic Brucellosis 27722176 "Altered Expressions of miR-1238-3p, miR-494, miR-6069, and miR-139-3p in the Formation of Chronic Brucellosis." tissue_expression_ns hsa-mir-494 Chronic Brucellosis 27722176 "Altered Expressions of miR-1238-3p, miR-494, miR-6069, and miR-139-3p in the Formation of Chronic Brucellosis." tissue_expression_ns hsa-mir-6069 Chronic Brucellosis 27722176 "Altered Expressions of miR-1238-3p, miR-494, miR-6069, and miR-139-3p in the Formation of Chronic Brucellosis." tissue_expression_ns hsa-mir-200 Cardiomyopathy 27737314 Analyzing gene expression profiles in dilated cardiomyopathy via bioinformatics methods. tissue_expression_ns hsa-mir-30 Cardiomyopathy 27737314 Analyzing gene expression profiles in dilated cardiomyopathy via bioinformatics methods. tissue_expression_ns hsa-mir-9 Cardiomyopathy 27737314 Analyzing gene expression profiles in dilated cardiomyopathy via bioinformatics methods. tissue_expression_ns hsa-mir-146a Diabetes Mellitus 27743454 "we present an overview of the roles of miRNAs in the islet ¦Â-cell development, focusing on the application of different miRNAs in the experimental protocols" tissue_expression_ns hsa-mir-200 Diabetes Mellitus 27743454 The role of microRNAs in islet ¦Â-cell development. tissue_expression_ns hsa-mir-30 Diabetes Mellitus 27743454 The role of microRNAs in islet ¦Â-cell development. tissue_expression_ns hsa-mir-342 Diabetes Mellitus 27743454 The role of microRNAs in islet ¦Â-cell development. tissue_expression_ns hsa-mir-34a Diabetes Mellitus 27743454 The role of microRNAs in islet ¦Â-cell development. tissue_expression_ns hsa-mir-375 Diabetes Mellitus 27743454 The role of microRNAs in islet ¦Â-cell development. tissue_expression_ns hsa-mir-7 Diabetes Mellitus 27743454 The role of microRNAs in islet ¦Â-cell development. tissue_expression_ns hsa-mir-1246 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-1268a "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-130a "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-138 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-139 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-197 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-200b "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-210 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-3613 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-4258 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-4298 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-452 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-4644 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-671 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-7107 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-7847 "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-90b "Carcinoma, Breast" 27746365 This study highlights the role of numerous miRNAs in prediction of therapeutic responses and suggests that specific miRNAs could serve as valuable sources for biomarker detections and optimal chemotherapeutic choices for breast cancer patients tissue_expression_ns hsa-mir-192 Colorectal Carcinoma 27747302 "high miR-192 and miR-194 correlate with better overall survival in Stage II patients, but worse survival in more advanced Stage III/IV patients" tissue_expression_ns hsa-mir-194 Colorectal Carcinoma 27747302 "high miR-192 and miR-194 correlate with better overall survival in Stage II patients, but worse survival in more advanced Stage III/IV patients" tissue_expression_ns hsa-mir-1244 Borna Disease 27748825 Identification and bioinformatic analysis of dysregulated microRNAs in human oligodendroglial cells infected with borna disease virus. tissue_expression_ns hsa-mir-1290 Borna Disease 27748825 Identification and bioinformatic analysis of dysregulated microRNAs in human oligodendroglial cells infected with borna disease virus. tissue_expression_ns hsa-mir-146a Borna Disease 27748825 Identification and bioinformatic analysis of dysregulated microRNAs in human oligodendroglial cells infected with borna disease virus. tissue_expression_ns hsa-mir-1908 Borna Disease 27748825 Identification and bioinformatic analysis of dysregulated microRNAs in human oligodendroglial cells infected with borna disease virus. tissue_expression_ns hsa-mir-296 Borna Disease 27748825 Identification and bioinformatic analysis of dysregulated microRNAs in human oligodendroglial cells infected with borna disease virus. tissue_expression_ns hsa-mir-3676 Borna Disease 27748825 Identification and bioinformatic analysis of dysregulated microRNAs in human oligodendroglial cells infected with borna disease virus. tissue_expression_ns hsa-mir-424 Borna Disease 27748825 Identification and bioinformatic analysis of dysregulated microRNAs in human oligodendroglial cells infected with borna disease virus. tissue_expression_ns hsa-mir-4521 Borna Disease 27748825 Identification and bioinformatic analysis of dysregulated microRNAs in human oligodendroglial cells infected with borna disease virus. tissue_expression_ns hsa-mir-7 Borna Disease 27748825 Identification and bioinformatic analysis of dysregulated microRNAs in human oligodendroglial cells infected with borna disease virus. tissue_expression_ns hsa-mir-449a "Carcinoma, Breast" 27748845 MicroRNA profiling in human breast cancer cell lines exposed to the anti-neoplastic drug cediranib. tissue_expression_ns hsa-mir-449b "Carcinoma, Breast" 27748845 MicroRNA profiling in human breast cancer cell lines exposed to the anti-neoplastic drug cediranib. tissue_expression_ns hsa-mir-494 "Carcinoma, Breast" 27748845 MicroRNA profiling in human breast cancer cell lines exposed to the anti-neoplastic drug cediranib. tissue_expression_ns hsa-mir-886 "Carcinoma, Breast" 27748845 MicroRNA profiling in human breast cancer cell lines exposed to the anti-neoplastic drug cediranib. tissue_expression_ns hsa-mir-923 "Carcinoma, Breast" 27748845 MicroRNA profiling in human breast cancer cell lines exposed to the anti-neoplastic drug cediranib. tissue_expression_ns hsa-mir-125a "Carcinoma, Lung" 27748875 MicroRNA expression profiles of granulocytic myeloid?derived suppressor cells from mice bearing Lewis lung carcinoma. tissue_expression_ns hsa-mir-125b "Carcinoma, Lung" 27748875 MicroRNA expression profiles of granulocytic myeloid?derived suppressor cells from mice bearing Lewis lung carcinoma. tissue_expression_ns hsa-mir-128 "Carcinoma, Lung" 27748875 MicroRNA expression profiles of granulocytic myeloid?derived suppressor cells from mice bearing Lewis lung carcinoma. tissue_expression_ns hsa-mir-149 "Carcinoma, Lung" 27748875 MicroRNA expression profiles of granulocytic myeloid?derived suppressor cells from mice bearing Lewis lung carcinoma. tissue_expression_ns hsa-mir-192 "Carcinoma, Lung" 27748875 MicroRNA expression profiles of granulocytic myeloid?derived suppressor cells from mice bearing Lewis lung carcinoma. tissue_expression_ns hsa-mir-27a "Carcinoma, Lung" 27748875 MicroRNA expression profiles of granulocytic myeloid?derived suppressor cells from mice bearing Lewis lung carcinoma. tissue_expression_ns hsa-mir-328 "Carcinoma, Lung" 27748875 MicroRNA expression profiles of granulocytic myeloid?derived suppressor cells from mice bearing Lewis lung carcinoma. tissue_expression_ns hsa-mir-350 "Carcinoma, Lung" 27748875 MicroRNA expression profiles of granulocytic myeloid?derived suppressor cells from mice bearing Lewis lung carcinoma. tissue_expression_ns hsa-mir-486 "Carcinoma, Lung" 27748875 MicroRNA expression profiles of granulocytic myeloid?derived suppressor cells from mice bearing Lewis lung carcinoma. tissue_expression_ns hsa-mir-143 "Carcinoma, Ovarian" 27748916 Dysregulation of micro-143-3p and BALBP1 contributes to the pathogenesis of the development of ovarian carcinoma. tissue_expression_ns hsa-let-7 Schizophrenia 27748930 "the possible role of let-7, miR-98 and miR-183 as biomarkers for Ca and SZ was investigated in our previous research studies" tissue_expression_ns hsa-mir-183 Schizophrenia 27748930 "the possible role of let-7, miR-98 and miR-183 as biomarkers for Ca and SZ was investigated in our previous research studies" tissue_expression_ns hsa-mir-98 Schizophrenia 27748930 "the possible role of let-7, miR-98 and miR-183 as biomarkers for Ca and SZ was investigated in our previous research studies" tissue_expression_ns hsa-mir-210 Human Immunodeficiency Virus Infection 27749601 "MicroRNA-210, MicroRNA-331, and MicroRNA-7 Are Differentially Regulated in Treated HIV-1-Infected Individuals and Are Associated With Markers of Systemic Inflammation." tissue_expression_ns hsa-mir-331 Human Immunodeficiency Virus Infection 27749601 "MicroRNA-210, MicroRNA-331, and MicroRNA-7 Are Differentially Regulated in Treated HIV-1-Infected Individuals and Are Associated With Markers of Systemic Inflammation." tissue_expression_ns hsa-mir-7 Human Immunodeficiency Virus Infection 27749601 "MicroRNA-210, MicroRNA-331, and MicroRNA-7 Are Differentially Regulated in Treated HIV-1-Infected Individuals and Are Associated With Markers of Systemic Inflammation." tissue_expression_ns hsa-mir-210 Ischemic Diseases [unspecific] 27750254 Temporal Profile of Circulating microRNAs after Global Hypoxia-Ischemia in Newborn Piglets. tissue_expression_ns hsa-mir-146a "Carcinoma, Bladder" 27751843 Real-time PCR analysis pointed to miR-375 as a biomarker for high-grade bladder cancer while miR-146a could identify low-grade patients tissue_expression_ns hsa-mir-375 "Carcinoma, Bladder" 27751843 Real-time PCR analysis pointed to miR-375 as a biomarker for high-grade bladder cancer while miR-146a could identify low-grade patients tissue_expression_ns hsa-mir-630 "Carcinoma, Urothelial" 27752905 Expression of miRNA-630 in bladder urothelial carcinoma and its clinical significance. tissue_expression_ns hsa-mir-941 Polyangiitis 27755585 MicroRNA-941 Expression in Polymorphonuclear Granulocytes Is Not Related to Granulomatosis with Polyangiitis. tissue_expression_ns hsa-mir-381 "Carcinoma, Ovarian" 27757782 Identification of candidate biomarkers and analysis of prognostic values in ovarian cancer by integrated bioinformatics analysis. tissue_expression_ns hsa-mir-424 "Carcinoma, Ovarian" 27757782 Identification of candidate biomarkers and analysis of prognostic values in ovarian cancer by integrated bioinformatics analysis. tissue_expression_ns hsa-mir-106b "Carcinoma, Cervical" 27764149 miRNA Expression Profiles of HPV-Infected Patients with Cervical Cancer in the Uyghur Population in China. tissue_expression_ns hsa-mir-15a "Carcinoma, Cervical" 27764149 miRNA Expression Profiles of HPV-Infected Patients with Cervical Cancer in the Uyghur Population in China. tissue_expression_ns hsa-mir-17 "Carcinoma, Cervical" 27764149 miRNA Expression Profiles of HPV-Infected Patients with Cervical Cancer in the Uyghur Population in China. tissue_expression_ns hsa-mir-20a "Carcinoma, Cervical" 27764149 miRNA Expression Profiles of HPV-Infected Patients with Cervical Cancer in the Uyghur Population in China. tissue_expression_ns hsa-mir-21 "Carcinoma, Cervical" 27764149 miRNA Expression Profiles of HPV-Infected Patients with Cervical Cancer in the Uyghur Population in China. tissue_expression_ns hsa-mir-3653 "Carcinoma, Cervical" 27764149 miRNA Expression Profiles of HPV-Infected Patients with Cervical Cancer in the Uyghur Population in China. tissue_expression_ns hsa-mir-497 "Carcinoma, Cervical" 27764149 miRNA Expression Profiles of HPV-Infected Patients with Cervical Cancer in the Uyghur Population in China. tissue_expression_ns hsa-mir-96 "Carcinoma, Cervical" 27764149 miRNA Expression Profiles of HPV-Infected Patients with Cervical Cancer in the Uyghur Population in China. tissue_expression_ns hsa-mir-133a Cardiovascular Diseases [unspecific] 27765794 Inhibition of Aberrant MicroRNA-133a Expression in Endothelial Cells by Statin Prevents Endothelial Dysfunction by Targeting GTP Cyclohydrolase 1 in Vivo. tissue_expression_ns hsa-mir-498 "Squamous Cell Carcinoma, Tongue" 27773646 MicroRNA and protein profiles in invasive versus non-invasive oral tongue squamous cell carcinoma cells in vitro. tissue_expression_ns hsa-mir-940 "Squamous Cell Carcinoma, Tongue" 27773646 MicroRNA and protein profiles in invasive versus non-invasive oral tongue squamous cell carcinoma cells in vitro. tissue_expression_ns hsa-mir-129 Amyotrophic Lateral Sclerosis 27773796 MicroRNA expression profiles of multiple system atrophy from formalin-fixed paraffin-embedded samples. tissue_expression_ns hsa-mir-132 Amyotrophic Lateral Sclerosis 27773796 MicroRNA expression profiles of multiple system atrophy from formalin-fixed paraffin-embedded samples. tissue_expression_ns hsa-mir-125 Colorectal Carcinoma 27775664 A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival. tissue_expression_ns hsa-mir-127 Colorectal Carcinoma 27775664 A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival. tissue_expression_ns hsa-mir-145 Colorectal Carcinoma 27775664 A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival. tissue_expression_ns hsa-mir-19 Colorectal Carcinoma 27775664 A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival. tissue_expression_ns hsa-mir-192 Colorectal Carcinoma 27775664 A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival. tissue_expression_ns hsa-mir-194 Colorectal Carcinoma 27775664 A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival. tissue_expression_ns hsa-mir-199 Colorectal Carcinoma 27775664 A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival. tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 27775664 A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival. tissue_expression_ns hsa-mir-215 Colorectal Carcinoma 27775664 A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival. tissue_expression_ns hsa-mir-429 Colorectal Carcinoma 27775664 A Comprehensive MicroRNA Expression Profile of Liver and Lung Metastases of Colorectal Cancer with Their Corresponding Host Tissue and Its Prognostic Impact on Survival. tissue_expression_ns hsa-mir-143 Inflammation 27776879 Expression Profiles of Inflammation-associated microRNAs in Periapical Lesions and Human Periodontal Ligament Fibroblasts Inflammation. tissue_expression_ns hsa-mir-223 Polycystic Ovarian Syndrome 27777110 Altered expression of miRNAs in the uterus from a letrozole-induced rat PCOS model. tissue_expression_ns hsa-mir-324 Polycystic Ovarian Syndrome 27777110 Altered expression of miRNAs in the uterus from a letrozole-induced rat PCOS model. tissue_expression_ns hsa-mir-375 Polycystic Ovarian Syndrome 27777110 Altered expression of miRNAs in the uterus from a letrozole-induced rat PCOS model. tissue_expression_ns hsa-mir-484 Polycystic Ovarian Syndrome 27777110 Altered expression of miRNAs in the uterus from a letrozole-induced rat PCOS model. tissue_expression_ns hsa-mir-152 Colorectal Carcinoma 27784461 Expression of microRNA-152 in colorectal cancer and its relationship with prognosis. tissue_expression_ns hsa-let-7d Reproductive System Disease 27789200 "A number of these differentially expressed miRNAs have previously been associated with adipogenesis(e.g. let-7d*, miR-103-2*, -130b, -146b-5-p, -29c, and -26b)" tissue_expression_ns hsa-mir-103-2 Reproductive System Disease 27789200 "A number of these differentially expressed miRNAs have previously been associated with adipogenesis(e.g. let-7d*, miR-103-2*, -130b, -146b-5-p, -29c, and -26b)" tissue_expression_ns hsa-mir-130b Reproductive System Disease 27789200 "A number of these differentially expressed miRNAs have previously been associated with adipogenesis(e.g. let-7d*, miR-103-2*, -130b, -146b-5-p, -29c, and -26b)" tissue_expression_ns hsa-mir-146b Reproductive System Disease 27789200 "A number of these differentially expressed miRNAs have previously been associated with adipogenesis(e.g. let-7d*, miR-103-2*, -130b, -146b-5-p, -29c, and -26b)" tissue_expression_ns hsa-mir-26b Reproductive System Disease 27789200 "A number of these differentially expressed miRNAs have previously been associated with adipogenesis(e.g. let-7d*, miR-103-2*, -130b, -146b-5-p, -29c, and -26b)" tissue_expression_ns hsa-mir-29c Reproductive System Disease 27789200 "A number of these differentially expressed miRNAs have previously been associated with adipogenesis(e.g. let-7d*, miR-103-2*, -130b, -146b-5-p, -29c, and -26b)" tissue_expression_ns hsa-mir-323a Epilepsy 27824513 Aberrant Expression of miR-323a-5p in Patients with Refractory Epilepsy Caused by Focal Cortical Dysplasia. tissue_expression_ns hsa-mir-9 Cerebral Aneurysm 27824808 Aberrant Expression of microRNA-9 Contributes to Development of Intracranial Aneurysm by Suppressing Proliferation and Reducing Contractility of Smooth Muscle Cells. tissue_expression_ns hsa-mir-1 Vascular Hypertrophy 27831640 Influence and significance of intervening diabetes microRNA expression profile of NOD mice with exendin-4. tissue_expression_ns hsa-let-7a Squamous Cell Carcinoma 27835588 Expressions of miR-30c and let-7a are inversely correlated with HMGA2 expression in squamous cell carcinoma of the vulva. tissue_expression_ns hsa-mir-4717 Guillain-Barre Syndrome 27836180 MicroRNA expression profiling in Guillain-Barr¨¦ syndrome. tissue_expression_ns hsa-mir-642b Guillain-Barre Syndrome 27836180 MicroRNA expression profiling in Guillain-Barr¨¦ syndrome. tissue_expression_ns hsa-mir-155 "Carcinoma, Pancreatic" 27840954 Identfication of key miRNAs in pancreatitis using bioinformatics analysis of microarray data. tissue_expression_ns hsa-mir-15a "Carcinoma, Pancreatic" 27840954 Identfication of key miRNAs in pancreatitis using bioinformatics analysis of microarray data. tissue_expression_ns hsa-mir-16 "Carcinoma, Pancreatic" 27840954 Identfication of key miRNAs in pancreatitis using bioinformatics analysis of microarray data. tissue_expression_ns hsa-mir-375 "Carcinoma, Pancreatic" 27840954 Identfication of key miRNAs in pancreatitis using bioinformatics analysis of microarray data. tissue_expression_ns hsa-mir-429 "Carcinoma, Pancreatic" 27840954 Identfication of key miRNAs in pancreatitis using bioinformatics analysis of microarray data. tissue_expression_ns hsa-mir-301a Melanoma 27855389 Expression of MicroRNA-301a and its Functional Roles in Malignant Melanoma. tissue_expression_ns hsa-mir-21 Peritoneal Dialysis Failure 27867039 Peritoneal dialysis effluent miR-21 and miR-589 levels correlate with longitudinal change in peritoneal transport characteristics. tissue_expression_ns hsa-mir-589 Peritoneal Dialysis Failure 27867039 Peritoneal dialysis effluent miR-21 and miR-589 levels correlate with longitudinal change in peritoneal transport characteristics. tissue_expression_ns hsa-mir-199a Autoimmune Diseases [unspecific] 27871116 "Excess glucocorticoids have been shown to modulate the expression of miRNAs, including miR-29a, miR-34a-5p, and miR-199a-5p, which regulate the proliferation and differentiation of osteoblast lineage cells" tissue_expression_ns hsa-mir-29a Autoimmune Diseases [unspecific] 27871116 "Excess glucocorticoids have been shown to modulate the expression of miRNAs, including miR-29a, miR-34a-5p, and miR-199a-5p, which regulate the proliferation and differentiation of osteoblast lineage cells" tissue_expression_ns hsa-mir-34a Autoimmune Diseases [unspecific] 27871116 "Excess glucocorticoids have been shown to modulate the expression of miRNAs, including miR-29a, miR-34a-5p, and miR-199a-5p, which regulate the proliferation and differentiation of osteoblast lineage cells" tissue_expression_ns hsa-mir-122 "Carcinoma, Hepatocellular" 27874954 The anti-cancer effects of cisplatin on hepatic cancer are associated with modulation of miRNA-21 and miRNA-122 expression. tissue_expression_ns hsa-mir-21 "Carcinoma, Hepatocellular" 27874954 The anti-cancer effects of cisplatin on hepatic cancer are associated with modulation of miRNA-21 and miRNA-122 expression. tissue_expression_ns hsa-mir-200b "Carcinoma, Lung, Non-Small-Cell" 27876017 miR-27b and miR-200b levels were determined in resected adenocarcinoma and squamous cell carcinoma samples by qRT-PCR tissue_expression_ns hsa-mir-27b "Carcinoma, Lung, Non-Small-Cell" 27876017 miR-27b and miR-200b levels were determined in resected adenocarcinoma and squamous cell carcinoma samples by qRT-PCR tissue_expression_ns hsa-mir-122 Liver Cirrhosis 27879410 We also detected expression of hsa-miR-122 in primitive ductular reactions expected for hepatocytic differentiation and hsa-miR-23b cluster expression that drives liver cell fate decisions in cells undergoing lineage commitment tissue_expression_ns hsa-mir-23b Liver Cirrhosis 27879410 We also detected expression of hsa-miR-122 in primitive ductular reactions expected for hepatocytic differentiation and hsa-miR-23b cluster expression that drives liver cell fate decisions in cells undergoing lineage commitment tissue_expression_ns hsa-mir-146a Chronic Hepatitis C 27888401 The impact of chronic hepatitis C infection on cholesterol metabolism in PBMCs is associated with microRNA-146a expression. tissue_expression_ns hsa-mir-186 "Squamous Cell Carcinoma, Esophageal" 27889881 Identification of reference genes and miRNAs for qRT-PCR in human esophageal squamous cell carcinoma. tissue_expression_ns hsa-mir-28 "Squamous Cell Carcinoma, Esophageal" 27889881 Identification of reference genes and miRNAs for qRT-PCR in human esophageal squamous cell carcinoma. tissue_expression_ns hsa-mir-34a "Squamous Cell Carcinoma, Esophageal" 27889881 Identification of reference genes and miRNAs for qRT-PCR in human esophageal squamous cell carcinoma. tissue_expression_ns hsa-let-7b "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-1179 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-1299 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-155 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-18a "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-19a "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-200a "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-21 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-3120 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-3149 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-3189 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-3622b "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-3677 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-3682 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-3689d "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-410 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-4469 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-4518 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-5189 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-639 "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-92b "Carcinoma, Prostate" 27903835 "the outcome of the study has important clinical implications for the management of prostate cancer, including the use of miRNA(s) as biomarkers for early detection of prostate cancer" tissue_expression_ns hsa-mir-210 "Stroke, Ischemic" 27906445 The expression research of miR-210 in the elderly patients with COPD combined with ischemic stroke. tissue_expression_ns hsa-mir-130a "Carcinoma, Prostate" 27915273 Altered miRNA expression in high-fat diet-induced prostate cancer progression. tissue_expression_ns hsa-mir-1276 "Carcinoma, Laryngeal" 27916417 "CCR6 was positively associated with miR-20a-5p, miR-489 and negatively related to miR-29-3p, miR-632 and miR-1276 in laryngeal cancer tissues" tissue_expression_ns hsa-mir-20a "Carcinoma, Laryngeal" 27916417 "CCR6 was positively associated with miR-20a-5p, miR-489 and negatively related to miR-29-3p, miR-632 and miR-1277 in laryngeal cancer tissues" tissue_expression_ns hsa-mir-29 "Carcinoma, Laryngeal" 27916417 "CCR6 was positively associated with miR-20a-5p, miR-489 and negatively related to miR-29-3p, miR-632 and miR-1278 in laryngeal cancer tissues" tissue_expression_ns hsa-mir-489 "Carcinoma, Laryngeal" 27916417 "CCR6 was positively associated with miR-20a-5p, miR-489 and negatively related to miR-29-3p, miR-632 and miR-1279 in laryngeal cancer tissues" tissue_expression_ns hsa-mir-632 "Carcinoma, Laryngeal" 27916417 "CCR6 was positively associated with miR-20a-5p, miR-489 and negatively related to miR-29-3p, miR-632 and miR-1280 in laryngeal cancer tissues" tissue_expression_ns hsa-mir-1246 Colorectal Carcinoma 27916938 Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells. tissue_expression_ns hsa-mir-1290 Colorectal Carcinoma 27916938 Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells. tissue_expression_ns hsa-mir-20a Colorectal Carcinoma 27916938 Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells. tissue_expression_ns hsa-mir-3142 Colorectal Carcinoma 27916938 Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells. tissue_expression_ns hsa-mir-3182 Colorectal Carcinoma 27916938 Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells. tissue_expression_ns hsa-mir-4286 Colorectal Carcinoma 27916938 Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells. tissue_expression_ns hsa-mir-4301 Colorectal Carcinoma 27916938 Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells. tissue_expression_ns hsa-mir-597 Colorectal Carcinoma 27916938 Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells. tissue_expression_ns hsa-mir-720 Colorectal Carcinoma 27916938 Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells. tissue_expression_ns hsa-mir-125b "Squamous Cell Carcinoma, Oral" 27935034 Integrated Analysis and MicroRNA Expression Profiling Identified Seven miRNAs Associated With Progression of Oral Squamous Cell Carcinoma. tissue_expression_ns hsa-mir-133a "Squamous Cell Carcinoma, Oral" 27935034 Integrated Analysis and MicroRNA Expression Profiling Identified Seven miRNAs Associated With Progression of Oral Squamous Cell Carcinoma. tissue_expression_ns hsa-mir-133b "Squamous Cell Carcinoma, Oral" 27935034 Integrated Analysis and MicroRNA Expression Profiling Identified Seven miRNAs Associated With Progression of Oral Squamous Cell Carcinoma. tissue_expression_ns hsa-mir-139 "Squamous Cell Carcinoma, Oral" 27935034 Integrated Analysis and MicroRNA Expression Profiling Identified Seven miRNAs Associated With Progression of Oral Squamous Cell Carcinoma. tissue_expression_ns hsa-mir-21 "Squamous Cell Carcinoma, Oral" 27935034 Integrated Analysis and MicroRNA Expression Profiling Identified Seven miRNAs Associated With Progression of Oral Squamous Cell Carcinoma. tissue_expression_ns hsa-mir-31 "Squamous Cell Carcinoma, Oral" 27935034 Integrated Analysis and MicroRNA Expression Profiling Identified Seven miRNAs Associated With Progression of Oral Squamous Cell Carcinoma. tissue_expression_ns hsa-mir-338 "Squamous Cell Carcinoma, Oral" 27935034 Integrated Analysis and MicroRNA Expression Profiling Identified Seven miRNAs Associated With Progression of Oral Squamous Cell Carcinoma. tissue_expression_ns hsa-mir-1 Aortic Aneurysm 27939432 Regulation of microRNA expression in vascular smooth muscle by MRTF-A and actin polymerization. tissue_expression_ns hsa-mir-143 Aortic Aneurysm 27939432 Regulation of microRNA expression in vascular smooth muscle by MRTF-A and actin polymerization. tissue_expression_ns hsa-mir-145 Aortic Aneurysm 27939432 Regulation of microRNA expression in vascular smooth muscle by MRTF-A and actin polymerization. tissue_expression_ns hsa-mir-22 Aortic Aneurysm 27939432 Regulation of microRNA expression in vascular smooth muscle by MRTF-A and actin polymerization. tissue_expression_ns hsa-mir-378a Aortic Aneurysm 27939432 Regulation of microRNA expression in vascular smooth muscle by MRTF-A and actin polymerization. tissue_expression_ns hsa-mir-203 "Squamous Cell Carcinoma, Skin or Unspecific" 27943259 MicroRNA (miR)-203 and miR-205 expression patterns identify subgroups of prognosis in cutaneous squamous cell carcinoma. tissue_expression_ns hsa-mir-205 "Squamous Cell Carcinoma, Skin or Unspecific" 27943259 MicroRNA (miR)-203 and miR-205 expression patterns identify subgroups of prognosis in cutaneous squamous cell carcinoma. tissue_expression_ns hsa-mir-15a Salivary Gland Neoplasms 27981346 Altered expression of apoptosis-regulating miRNAs in salivary gland tumors suggests their involvement in salivary gland tumorigenesis. tissue_expression_ns hsa-mir-16 Salivary Gland Neoplasms 27981346 Altered expression of apoptosis-regulating miRNAs in salivary gland tumors suggests their involvement in salivary gland tumorigenesis. tissue_expression_ns hsa-mir-17 Salivary Gland Neoplasms 27981346 Altered expression of apoptosis-regulating miRNAs in salivary gland tumors suggests their involvement in salivary gland tumorigenesis. tissue_expression_ns hsa-mir-20a Salivary Gland Neoplasms 27981346 Altered expression of apoptosis-regulating miRNAs in salivary gland tumors suggests their involvement in salivary gland tumorigenesis. tissue_expression_ns hsa-mir-21 Salivary Gland Neoplasms 27981346 Altered expression of apoptosis-regulating miRNAs in salivary gland tumors suggests their involvement in salivary gland tumorigenesis. tissue_expression_ns hsa-mir-29 Salivary Gland Neoplasms 27981346 Altered expression of apoptosis-regulating miRNAs in salivary gland tumors suggests their involvement in salivary gland tumorigenesis. tissue_expression_ns hsa-mir-34 Salivary Gland Neoplasms 27981346 Altered expression of apoptosis-regulating miRNAs in salivary gland tumors suggests their involvement in salivary gland tumorigenesis. tissue_expression_ns hsa-mir-34a Salivary Gland Neoplasms 27981346 Altered expression of apoptosis-regulating miRNAs in salivary gland tumors suggests their involvement in salivary gland tumorigenesis. tissue_expression_ns hsa-mir-106b "Squamous Cell Carcinoma, Esophageal" 27998862 Expression of mir-106b in esophageal squamous cell carcinoma. tissue_expression_ns hsa-mir-107 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-126 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-135 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-137 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-138 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-145 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-150 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-155 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-181a Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-184 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-205 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-21 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-218 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-7 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-9 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-98 Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-99b Glioma 27999452 "Deregulation of miRNAs is caused by viral infections, tumorigenesis, and so forth" tissue_expression_ns hsa-mir-29a Diabetes Mellitus 28003969 Expression and regulation of microRNA-29a and microRNA-29c in early diabetic rat cataract formation. tissue_expression_ns hsa-mir-29c Diabetes Mellitus 28003969 Expression and regulation of microRNA-29a and microRNA-29c in early diabetic rat cataract formation. tissue_expression_ns hsa-mir-26a Pituitary Adenoma 28012286 Expression and Clinical Significance of miR-26a and Pleomorphic Adenoma Gene 1 (PLAG1) in Invasive Pituitary Adenoma. tissue_expression_ns hsa-mir-142 Lymphoma 28031239 "MicroRNAs 142-3p, miR-155 and miR-203 Are Deregulated in Gastric MALT Lymphomas Compared to Chronic Gastritis." tissue_expression_ns hsa-mir-155 Lymphoma 28031239 "MicroRNAs 142-3p, miR-155 and miR-203 Are Deregulated in Gastric MALT Lymphomas Compared to Chronic Gastritis." tissue_expression_ns hsa-mir-203 Lymphoma 28031239 "MicroRNAs 142-3p, miR-155 and miR-203 Are Deregulated in Gastric MALT Lymphomas Compared to Chronic Gastritis." tissue_expression_ns hsa-mir-34b Prostate Neoplasms 28039468 Differential expression of miR-34b and androgen receptor pathway regulate prostate cancer aggressiveness between African-Americans and Caucasians. tissue_expression_ns hsa-mir-29 Malignant Neoplasms [unspecific] 28063172 Prognostic value of the MicroRNA-29 family in multiple human cancers: A meta-analysis and systematic review. tissue_expression_ns hsa-mir-140 Osteoarthritis 28065216 Expression of miRNA-140 in Chondrocytes and Synovial Fluid of Knee Joints in Patients with Osteoarthritis. tissue_expression_ns hsa-mir-155 Porphyromonas Gingivalis 28069815 Identification and Characterization of MicroRNA Differentially Expressed in Macrophages Exposed to Porphyromonas gingivalis Infection. tissue_expression_ns hsa-mir-1184 "Carcinoma, Prostate" 28072703 Screening the key microRNAs and transcription factors in prostate cancer based on microRNA functional synergistic relationships. tissue_expression_ns hsa-mir-1207 "Carcinoma, Prostate" 28072703 Screening the key microRNAs and transcription factors in prostate cancer based on microRNA functional synergistic relationships. tissue_expression_ns hsa-mir-182 "Carcinoma, Prostate" 28072703 Screening the key microRNAs and transcription factors in prostate cancer based on microRNA functional synergistic relationships. tissue_expression_ns hsa-mir-183 "Carcinoma, Prostate" 28072703 Screening the key microRNAs and transcription factors in prostate cancer based on microRNA functional synergistic relationships. tissue_expression_ns hsa-mir-24 "Carcinoma, Prostate" 28072703 Screening the key microRNAs and transcription factors in prostate cancer based on microRNA functional synergistic relationships. tissue_expression_ns hsa-mir-223 Lyme Disease 28076897 MicroRNA Expression Shows Inflammatory Dysregulation and Tumor-Like Proliferative Responses in Joints of Patients With Postinfectious Lyme Arthritis. tissue_expression_ns hsa-mir-106a Psoriasis 28077577 Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity. tissue_expression_ns hsa-mir-146a Psoriasis 28077577 Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity. tissue_expression_ns hsa-mir-150 Psoriasis 28077577 Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity. tissue_expression_ns hsa-mir-155 Psoriasis 28077577 Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity. tissue_expression_ns hsa-mir-19a Psoriasis 28077577 Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity. tissue_expression_ns hsa-mir-21 Psoriasis 28077577 Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity. tissue_expression_ns hsa-mir-1 Myotonic Muscular Dystrophy 28078570 Micro-RNA expression in muscle and fiber morphometry in myotonic dystrophy type 1. tissue_expression_ns hsa-mir-133a Myotonic Muscular Dystrophy 28078570 Micro-RNA expression in muscle and fiber morphometry in myotonic dystrophy type 1. tissue_expression_ns hsa-mir-133b Myotonic Muscular Dystrophy 28078570 Micro-RNA expression in muscle and fiber morphometry in myotonic dystrophy type 1. tissue_expression_ns hsa-mir-206 Myotonic Muscular Dystrophy 28078570 Micro-RNA expression in muscle and fiber morphometry in myotonic dystrophy type 1. tissue_expression_ns hsa-mir-126 Vascular Disease [unspecific] 28082910 "Acute Effects of Different Exercise Protocols on the Circulating Vascular microRNAs -16, -21, and -126 in Trained Subjects." tissue_expression_ns hsa-mir-16 Vascular Disease [unspecific] 28082910 "Acute Effects of Different Exercise Protocols on the Circulating Vascular microRNAs -16, -21, and -126 in Trained Subjects." tissue_expression_ns hsa-mir-21 Vascular Disease [unspecific] 28082910 "Acute Effects of Different Exercise Protocols on the Circulating Vascular microRNAs -16, -21, and -126 in Trained Subjects." tissue_expression_ns hsa-mir-140 Osteoarthritis 28085114 Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/¦Â-Catenin Pathway. tissue_expression_ns hsa-mir-146a Osteoarthritis 28085114 Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/¦Â-Catenin Pathway. tissue_expression_ns hsa-mir-146b Osteoarthritis 28085114 Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/¦Â-Catenin Pathway. tissue_expression_ns hsa-mir-27a Osteoarthritis 28085114 Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/¦Â-Catenin Pathway. tissue_expression_ns hsa-mir-27b Osteoarthritis 28085114 Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/¦Â-Catenin Pathway. tissue_expression_ns hsa-mir-365 Osteoarthritis 28085114 Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/¦Â-Catenin Pathway. tissue_expression_ns hsa-mir-2278 "Carcinoma, Renal Cell" 28099931 A new semisynthetic cardenolide analog 3¦Â-2-(1-amantadine)- 1-on-ethylamine-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines. tissue_expression_ns hsa-mir-670 "Carcinoma, Renal Cell" 28099931 A new semisynthetic cardenolide analog 3¦Â-2-(1-amantadine)- 1-on-ethylamine-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines. tissue_expression_ns hsa-mir-10b Breast Neoplasms 28101798 "miR-10b, miR-26a, miR-146a And miR-153 Expression in Triple Negative Vs Non Triple Negative Breast Cancer: Potential Biomarkers." tissue_expression_ns hsa-mir-146a Breast Neoplasms 28101798 "miR-10b, miR-26a, miR-146a And miR-153 Expression in Triple Negative Vs Non Triple Negative Breast Cancer: Potential Biomarkers." tissue_expression_ns hsa-mir-153 Breast Neoplasms 28101798 "miR-10b, miR-26a, miR-146a And miR-153 Expression in Triple Negative Vs Non Triple Negative Breast Cancer: Potential Biomarkers." tissue_expression_ns hsa-mir-26a Breast Neoplasms 28101798 "miR-10b, miR-26a, miR-146a And miR-153 Expression in Triple Negative Vs Non Triple Negative Breast Cancer: Potential Biomarkers." tissue_expression_ns hsa-mir-17 Leukemia 28105201 "Comparison of microRNA expression profiles in K562-cells-derived microvesicles and parental cells, and analysis of their roles in leukemia." tissue_expression_ns hsa-mir-638 "Squamous Cell Carcinoma, Esophageal" 28108314 MiRNA-638 promotes autophagy and malignant phenotypes of cancer cells via directly suppressing DACT3. tissue_expression_ns hsa-mir-141 "Adenocarcinoma, Sebaceous" 28119291 miRNA-200c and miRNA-141 as potential prognostic biomarkers and regulators of epithelial-mesenchymal transition in eyelid sebaceous gland carcinoma. tissue_expression_ns hsa-mir-200c "Adenocarcinoma, Sebaceous" 28119291 miRNA-200c and miRNA-141 as potential prognostic biomarkers and regulators of epithelial-mesenchymal transition in eyelid sebaceous gland carcinoma. tissue_expression_ns hsa-mir-223 Penis Carcinoma 28122331 Integrative miRNA and mRNA analysis in penile carcinomas reveals markers and pathways with potential clinical impact. tissue_expression_ns hsa-mir-224 Penis Carcinoma 28122331 Integrative miRNA and mRNA analysis in penile carcinomas reveals markers and pathways with potential clinical impact. tissue_expression_ns hsa-mir-31 Penis Carcinoma 28122331 Integrative miRNA and mRNA analysis in penile carcinomas reveals markers and pathways with potential clinical impact. tissue_expression_ns hsa-mir-16 Endometrial Neoplasms 28129244 Aberrant MicroRNA Expression in Patients With Endometrial Cancer. tissue_expression_ns hsa-mir-106b Chronic Kidney Disease 28148896 "Investigated the safety of intra-renal arterial transfusion of autologous CD34+ cells and time courses of creatinine levels, endothelial dysfunction biomarkers and micro-RNAs in chronic kidney disease patients-phase I clinical trial." tissue_expression_ns hsa-mir-19a Chronic Kidney Disease 28148896 "Investigated the safety of intra-renal arterial transfusion of autologous CD34+ cells and time courses of creatinine levels, endothelial dysfunction biomarkers and micro-RNAs in chronic kidney disease patients-phase I clinical trial." tissue_expression_ns hsa-mir-20a Chronic Kidney Disease 28148896 "Investigated the safety of intra-renal arterial transfusion of autologous CD34+ cells and time courses of creatinine levels, endothelial dysfunction biomarkers and micro-RNAs in chronic kidney disease patients-phase I clinical trial." tissue_expression_ns hsa-mir-26b Chronic Kidney Disease 28148896 "Investigated the safety of intra-renal arterial transfusion of autologous CD34+ cells and time courses of creatinine levels, endothelial dysfunction biomarkers and micro-RNAs in chronic kidney disease patients-phase I clinical trial." tissue_expression_ns hsa-mir-374a Chronic Kidney Disease 28148896 "Investigated the safety of intra-renal arterial transfusion of autologous CD34+ cells and time courses of creatinine levels, endothelial dysfunction biomarkers and micro-RNAs in chronic kidney disease patients-phase I clinical trial." tissue_expression_ns hsa-mir-122 "Carcinoma, Renal Cell, Clear-Cell" 28184927 "miR-122 and miR-34a, respectively, may regulate their expression in this cancer" tissue_expression_ns hsa-mir-34a "Carcinoma, Renal Cell, Clear-Cell" 28184927 Downregulation of OCLN and GAS1 in clear cell renal cell carcinoma. tissue_expression_ns hsa-mir-21 Pancreatic Neoplasms 28186267 "We also examined miRNA expression [microRNA-21 (miR-21) and microRNA-31 (miR-31)] and epigenetic alterations, including CpG island methylator phenotype (CIMP), potentially associated with the identified miRNAs" tissue_expression_ns hsa-mir-31 Pancreatic Neoplasms 28186267 "We also examined miRNA expression [microRNA-21 (miR-21) and microRNA-31 (miR-31)] and epigenetic alterations, including CpG island methylator phenotype (CIMP), potentially associated with the identified miRNAs" tissue_expression_ns hsa-mir-155 Asthma 28199728 Altered miR-155 Expression in Allergic Asthmatic Airways. tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 28207045 Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance. tissue_expression_ns hsa-mir-210 Colorectal Carcinoma 28207045 Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance. tissue_expression_ns hsa-mir-30d Colorectal Carcinoma 28207045 Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance. tissue_expression_ns hsa-mir-19a Osteosarcoma 28214202 Elevated expression of microRNA-19a predicts a poor prognosis in patients with osteosarcoma. tissue_expression_ns hsa-let-7a Cutaneous Melanoma 28218741 Identification of microRNAs associated with invasive and aggressive phenotype in cutaneous melanoma by next-generation sequencing. tissue_expression_ns hsa-let-7b Cutaneous Melanoma 28218741 Identification of microRNAs associated with invasive and aggressive phenotype in cutaneous melanoma by next-generation sequencing. tissue_expression_ns hsa-mir-182 Cutaneous Melanoma 28218741 Identification of microRNAs associated with invasive and aggressive phenotype in cutaneous melanoma by next-generation sequencing. tissue_expression_ns hsa-mir-199b Cutaneous Melanoma 28218741 Identification of microRNAs associated with invasive and aggressive phenotype in cutaneous melanoma by next-generation sequencing. tissue_expression_ns hsa-mir-205 Cutaneous Melanoma 28218741 Identification of microRNAs associated with invasive and aggressive phenotype in cutaneous melanoma by next-generation sequencing. tissue_expression_ns hsa-mir-21 Cutaneous Melanoma 28218741 Identification of microRNAs associated with invasive and aggressive phenotype in cutaneous melanoma by next-generation sequencing. tissue_expression_ns hsa-mir-423 Cutaneous Melanoma 28218741 Identification of microRNAs associated with invasive and aggressive phenotype in cutaneous melanoma by next-generation sequencing. tissue_expression_ns hsa-mir-424 Cutaneous Melanoma 28218741 Identification of microRNAs associated with invasive and aggressive phenotype in cutaneous melanoma by next-generation sequencing. tissue_expression_ns hsa-mir-26a "Carcinoma, Hepatocellular" 28218742 "MiRNA expression profiles reveal the involvement of miR-26a, miR-548l and miR-34a in hepatocellular carcinoma progression through regulation of ST3GAL5." tissue_expression_ns hsa-mir-34a "Carcinoma, Hepatocellular" 28218742 "MiRNA expression profiles reveal the involvement of miR-26a, miR-548l and miR-34a in hepatocellular carcinoma progression through regulation of ST3GAL5." tissue_expression_ns hsa-mir-548l "Carcinoma, Hepatocellular" 28218742 "MiRNA expression profiles reveal the involvement of miR-26a, miR-548l and miR-34a in hepatocellular carcinoma progression through regulation of ST3GAL5." tissue_expression_ns hsa-mir-17 Neoplasms [unspecific] 28222938 The role of miR-17-92 cluster in the expression of tumor suppressor genes in unrestricted somatic stem cells. tissue_expression_ns hsa-mir-18a Neoplasms [unspecific] 28222938 The role of miR-17-92 cluster in the expression of tumor suppressor genes in unrestricted somatic stem cells. tissue_expression_ns hsa-mir-19a Neoplasms [unspecific] 28222938 The role of miR-17-92 cluster in the expression of tumor suppressor genes in unrestricted somatic stem cells. tissue_expression_ns hsa-mir-19b Neoplasms [unspecific] 28222938 The role of miR-17-92 cluster in the expression of tumor suppressor genes in unrestricted somatic stem cells. tissue_expression_ns hsa-mir-20a Neoplasms [unspecific] 28222938 The role of miR-17-92 cluster in the expression of tumor suppressor genes in unrestricted somatic stem cells. tissue_expression_ns hsa-mir-92a Neoplasms [unspecific] 28222938 The role of miR-17-92 cluster in the expression of tumor suppressor genes in unrestricted somatic stem cells. tissue_expression_ns hsa-mir-155 Atherosclerosis 28234622 "CagA-positive and CagA-negative Helicobacter pylori strains differentially affect the expression of micro RNAs 21, 92a, 155 and 663 in human umbilical vein endothelial cells." tissue_expression_ns hsa-mir-21 Atherosclerosis 28234622 "CagA-positive and CagA-negative Helicobacter pylori strains differentially affect the expression of micro RNAs 21, 92a, 155 and 663 in human umbilical vein endothelial cells." tissue_expression_ns hsa-mir-663 Atherosclerosis 28234622 "CagA-positive and CagA-negative Helicobacter pylori strains differentially affect the expression of micro RNAs 21, 92a, 155 and 663 in human umbilical vein endothelial cells." tissue_expression_ns hsa-mir-92a Atherosclerosis 28234622 "CagA-positive and CagA-negative Helicobacter pylori strains differentially affect the expression of micro RNAs 21, 92a, 155 and 663 in human umbilical vein endothelial cells." tissue_expression_ns hsa-mir-127 Prostate Neoplasms 28239051 MicroRNA expression profiling in canine prostate cancer. tissue_expression_ns hsa-mir-203 Endomyocardial Fibrosis 28272698 Effect of miR-203 expression on myocardial fibrosis. tissue_expression_ns hsa-mir-122 "Carcinoma, Hepatocellular" 28272709 Expression of microRNA-122 and microRNA-22 in HBV-related liver cancer and the correlation with clinical features. tissue_expression_ns hsa-mir-22 "Carcinoma, Hepatocellular" 28272709 Expression of microRNA-122 and microRNA-22 in HBV-related liver cancer and the correlation with clinical features. tissue_expression_ns hsa-mir-106b Osteosarcoma 28272712 The expression and function of miRNA-106 in pediatric osteosarcoma. tissue_expression_ns hsa-mir-542 "Squamous Cell Carcinoma, Oral" 28275798 Expression and correlation of survivin and hsa-miR-542-3p in patients with oral squamous cell carcinoma. tissue_expression_ns hsa-mir-10b Colorectal Carcinoma 28289479 Colorectal adenoma and carcinoma specific miRNA profiles in biopsy and their expression in plasma specimens. tissue_expression_ns hsa-mir-183 Colorectal Carcinoma 28289479 Colorectal adenoma and carcinoma specific miRNA profiles in biopsy and their expression in plasma specimens. tissue_expression_ns hsa-let-7a Pituitary Neoplasms 28300776 Evolution of Fish Let-7 MicroRNAs and Their Expression Correlated to Growth Development in Blunt Snout Bream. tissue_expression_ns hsa-let-7b Pituitary Neoplasms 28300776 Evolution of Fish Let-7 MicroRNAs and Their Expression Correlated to Growth Development in Blunt Snout Bream. tissue_expression_ns hsa-let-7c Pituitary Neoplasms 28300776 Evolution of Fish Let-7 MicroRNAs and Their Expression Correlated to Growth Development in Blunt Snout Bream. tissue_expression_ns hsa-let-7d Pituitary Neoplasms 28300776 Evolution of Fish Let-7 MicroRNAs and Their Expression Correlated to Growth Development in Blunt Snout Bream. tissue_expression_ns hsa-let-7e Pituitary Neoplasms 28300776 Evolution of Fish Let-7 MicroRNAs and Their Expression Correlated to Growth Development in Blunt Snout Bream. tissue_expression_ns hsa-let-7f Pituitary Neoplasms 28300776 Evolution of Fish Let-7 MicroRNAs and Their Expression Correlated to Growth Development in Blunt Snout Bream. tissue_expression_ns hsa-let-7g Pituitary Neoplasms 28300776 Evolution of Fish Let-7 MicroRNAs and Their Expression Correlated to Growth Development in Blunt Snout Bream. tissue_expression_ns hsa-let-7i Pituitary Neoplasms 28300776 Evolution of Fish Let-7 MicroRNAs and Their Expression Correlated to Growth Development in Blunt Snout Bream. tissue_expression_ns hsa-mir-150 Human Papilloma Virus Infection 28302562 Dysregulated expression of microRNA-150 in human papillomavirus-induced lesions of K14-HPV16 transgenic mice. tissue_expression_ns hsa-mir-181a Pituitary Adenoma 28315020 Novel Biomarkers for Non-functioning Invasive Pituitary Adenomas were Identified by Using Analysis of microRNAs Expression Profile. tissue_expression_ns hsa-mir-181b Pituitary Adenoma 28315020 Novel Biomarkers for Non-functioning Invasive Pituitary Adenomas were Identified by Using Analysis of microRNAs Expression Profile. tissue_expression_ns hsa-mir-181d Pituitary Adenoma 28315020 Novel Biomarkers for Non-functioning Invasive Pituitary Adenomas were Identified by Using Analysis of microRNAs Expression Profile. tissue_expression_ns hsa-mir-191 Pituitary Adenoma 28315020 Novel Biomarkers for Non-functioning Invasive Pituitary Adenomas were Identified by Using Analysis of microRNAs Expression Profile. tissue_expression_ns hsa-mir-3676 Pituitary Adenoma 28315020 Novel Biomarkers for Non-functioning Invasive Pituitary Adenomas were Identified by Using Analysis of microRNAs Expression Profile. tissue_expression_ns hsa-mir-383 Pituitary Adenoma 28315020 Novel Biomarkers for Non-functioning Invasive Pituitary Adenomas were Identified by Using Analysis of microRNAs Expression Profile. tissue_expression_ns hsa-mir-598 Pituitary Adenoma 28315020 Novel Biomarkers for Non-functioning Invasive Pituitary Adenomas were Identified by Using Analysis of microRNAs Expression Profile. tissue_expression_ns hsa-mir-146a Sjogren Syndrome 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-146a Systemic Lupus Erythematosus 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-148a Sjogren Syndrome 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-148a Systemic Lupus Erythematosus 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-150 Sjogren Syndrome 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-150 Systemic Lupus Erythematosus 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-152 Sjogren Syndrome 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-152 Systemic Lupus Erythematosus 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-155 Sjogren Syndrome 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-155 Systemic Lupus Erythematosus 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-16 Sjogren Syndrome 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-16 Systemic Lupus Erythematosus 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-21 Sjogren Syndrome 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-21 Systemic Lupus Erythematosus 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-223 Sjogren Syndrome 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-223 Systemic Lupus Erythematosus 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-224 Sjogren Syndrome 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-224 Systemic Lupus Erythematosus 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-326 Sjogren Syndrome 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-326 Systemic Lupus Erythematosus 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-342 Sjogren Syndrome 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-342 Systemic Lupus Erythematosus 28339495 MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sj?gren's syndrome. tissue_expression_ns hsa-mir-149 "Adenocarcinoma, Lung" 28345454 Genome-wide profiling of micro-RNA expression in gefitinib-resistant human lung adenocarcinoma using microarray for the identification of miR-149-5p modulation. tissue_expression_ns hsa-mir-155 "Squamous Cell Carcinoma, Head and Neck" 28347920 MiR-200b and miR-155 as predictive biomarkers for the efficacy of chemoradiation in locally advanced head and neck squamous cell carcinoma. tissue_expression_ns hsa-mir-200b "Squamous Cell Carcinoma, Head and Neck" 28347920 MiR-200b and miR-155 as predictive biomarkers for the efficacy of chemoradiation in locally advanced head and neck squamous cell carcinoma. tissue_expression_ns hsa-mir-107 Meningioma 28349893 "Expression of miRNA-21, miRNA-107, miRNA-137 and miRNA-29b in meningioma." tissue_expression_ns hsa-mir-137 Meningioma 28349893 "Expression of miRNA-21, miRNA-107, miRNA-137 and miRNA-29b in meningioma." tissue_expression_ns hsa-mir-21 Meningioma 28349893 "Expression of miRNA-21, miRNA-107, miRNA-137 and miRNA-29b in meningioma." tissue_expression_ns hsa-mir-29b Meningioma 28349893 "Expression of miRNA-21, miRNA-107, miRNA-137 and miRNA-29b in meningioma." tissue_expression_ns hsa-let-7a Salivary Gland Neoplasms 28377929 "Expression, Mutation, and Amplification Status of EGFR and Its Correlation with Five miRNAs in Salivary Gland Tumours." tissue_expression_ns hsa-mir-133b Salivary Gland Neoplasms 28377929 "Expression, Mutation, and Amplification Status of EGFR and Its Correlation with Five miRNAs in Salivary Gland Tumours." tissue_expression_ns hsa-mir-140 Salivary Gland Neoplasms 28377929 "Expression, Mutation, and Amplification Status of EGFR and Its Correlation with Five miRNAs in Salivary Gland Tumours." tissue_expression_ns hsa-mir-99b Salivary Gland Neoplasms 28377929 "Expression, Mutation, and Amplification Status of EGFR and Its Correlation with Five miRNAs in Salivary Gland Tumours." tissue_expression_ns hsa-mir-516 Gestational Trophoblastic Disease 28381180 "Follow-up of gestational trophoblastic disease/neoplasia via quantification of circulating nucleic acids of placental origin using C19MC microRNAs, hypermethylated RASSF1A, and SRY sequences." tissue_expression_ns hsa-mir-517 Gestational Trophoblastic Disease 28381180 "Follow-up of gestational trophoblastic disease/neoplasia via quantification of circulating nucleic acids of placental origin using C19MC microRNAs, hypermethylated RASSF1A, and SRY sequences." tissue_expression_ns hsa-mir-518b Gestational Trophoblastic Disease 28381180 "Follow-up of gestational trophoblastic disease/neoplasia via quantification of circulating nucleic acids of placental origin using C19MC microRNAs, hypermethylated RASSF1A, and SRY sequences." tissue_expression_ns hsa-mir-520a Gestational Trophoblastic Disease 28381180 "Follow-up of gestational trophoblastic disease/neoplasia via quantification of circulating nucleic acids of placental origin using C19MC microRNAs, hypermethylated RASSF1A, and SRY sequences." tissue_expression_ns hsa-mir-520h Gestational Trophoblastic Disease 28381180 "Follow-up of gestational trophoblastic disease/neoplasia via quantification of circulating nucleic acids of placental origin using C19MC microRNAs, hypermethylated RASSF1A, and SRY sequences." tissue_expression_ns hsa-mir-525 Gestational Trophoblastic Disease 28381180 "Follow-up of gestational trophoblastic disease/neoplasia via quantification of circulating nucleic acids of placental origin using C19MC microRNAs, hypermethylated RASSF1A, and SRY sequences." tissue_expression_ns hsa-mir-526a Gestational Trophoblastic Disease 28381180 "Follow-up of gestational trophoblastic disease/neoplasia via quantification of circulating nucleic acids of placental origin using C19MC microRNAs, hypermethylated RASSF1A, and SRY sequences." tissue_expression_ns hsa-mir-370 Obesity 28386478 Changes in the MicroRNA Profile Observed in the Subcutaneous Adipose Tissue of Obese Patients after Laparoscopic Adjustable Gastric Banding. tissue_expression_ns hsa-mir-1179 "Carcinoma, Thyroid, Papillary" 28393181 different miRNA expression profiles are associated with different histological types of PTC and different risks of recurrence tissue_expression_ns hsa-mir-140 "Carcinoma, Thyroid, Papillary" 28393181 different miRNA expression profiles are associated with different histological types of PTC and different risks of recurrence tissue_expression_ns hsa-mir-144 "Carcinoma, Thyroid, Papillary" 28393181 different miRNA expression profiles are associated with different histological types of PTC and different risks of recurrence tissue_expression_ns hsa-mir-146b "Carcinoma, Thyroid, Papillary" 28393181 different miRNA expression profiles are associated with different histological types of PTC and different risks of recurrence tissue_expression_ns hsa-mir-204 "Carcinoma, Thyroid, Papillary" 28393181 different miRNA expression profiles are associated with different histological types of PTC and different risks of recurrence tissue_expression_ns hsa-mir-21 "Carcinoma, Thyroid, Papillary" 28393181 different miRNA expression profiles are associated with different histological types of PTC and different risks of recurrence tissue_expression_ns hsa-mir-221 "Carcinoma, Thyroid, Papillary" 28393181 different miRNA expression profiles are associated with different histological types of PTC and different risks of recurrence tissue_expression_ns hsa-mir-222 "Carcinoma, Thyroid, Papillary" 28393181 different miRNA expression profiles are associated with different histological types of PTC and different risks of recurrence tissue_expression_ns hsa-mir-486 "Carcinoma, Thyroid, Papillary" 28393181 different miRNA expression profiles are associated with different histological types of PTC and different risks of recurrence tissue_expression_ns hsa-mir-7 "Carcinoma, Thyroid, Papillary" 28393181 different miRNA expression profiles are associated with different histological types of PTC and different risks of recurrence tissue_expression_ns hsa-mir-200b Gastrointestinal Neoplasms 28402940 Prognostic role of microRNAs in human gastrointestinal cancer: A systematic review and meta-analysis. tissue_expression_ns hsa-mir-200c Gastrointestinal Neoplasms 28402940 Prognostic role of microRNAs in human gastrointestinal cancer: A systematic review and meta-analysis. tissue_expression_ns hsa-mir-203 "Carcinoma, Rectal" 28403349 "Analysis of gene expression EGFR and KRAS, microRNA-21 and microRNA-203 in patients with colon and rectal cancer and correlation with clinical outcome and prognostic factors." tissue_expression_ns hsa-mir-21 "Carcinoma, Rectal" 28403349 "Analysis of gene expression EGFR and KRAS, microRNA-21 and microRNA-203 in patients with colon and rectal cancer and correlation with clinical outcome and prognostic factors." tissue_expression_ns hsa-mir-10a Atherosclerosis 28403739 "Hydrogen Peroxide and Lipopolysaccharide Differentially Affect the Expression of MicroRNAs 10a, 33a, 21, 221 in Endothelial Cells Before and After Coculture With Monocytes." tissue_expression_ns hsa-mir-21 Atherosclerosis 28403739 "Hydrogen Peroxide and Lipopolysaccharide Differentially Affect the Expression of MicroRNAs 10a, 33a, 21, 221 in Endothelial Cells Before and After Coculture With Monocytes." tissue_expression_ns hsa-mir-221 Atherosclerosis 28403739 "Hydrogen Peroxide and Lipopolysaccharide Differentially Affect the Expression of MicroRNAs 10a, 33a, 21, 221 in Endothelial Cells Before and After Coculture With Monocytes." tissue_expression_ns hsa-mir-33a Atherosclerosis 28403739 "Hydrogen Peroxide and Lipopolysaccharide Differentially Affect the Expression of MicroRNAs 10a, 33a, 21, 221 in Endothelial Cells Before and After Coculture With Monocytes." tissue_expression_ns hsa-mir-150 Burns 28404517 Dysregulation of microRNA biogenesis in the small intestine after ethanol and burn injury. tissue_expression_ns hsa-let-7d Kidney Diseases [unspecific] 28414804 Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity. tissue_expression_ns hsa-mir-130 Kidney Diseases [unspecific] 28414804 Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity. tissue_expression_ns hsa-mir-186 Kidney Diseases [unspecific] 28414804 Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity. tissue_expression_ns hsa-mir-192 Kidney Diseases [unspecific] 28414804 Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity. tissue_expression_ns hsa-mir-200 Kidney Diseases [unspecific] 28414804 Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity. tissue_expression_ns hsa-mir-21 Kidney Diseases [unspecific] 28414804 Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity. tissue_expression_ns hsa-mir-29 Kidney Diseases [unspecific] 28414804 Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity. tissue_expression_ns hsa-mir-30 Kidney Diseases [unspecific] 28414804 Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity. tissue_expression_ns hsa-mir-709 Kidney Diseases [unspecific] 28414804 Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity. tissue_expression_ns hsa-let-7a Ovarian Neoplasms 28423547 Genomic imbalances are involved in miR-30c and let-7a deregulation in ovarian tumors: implications for HMGA2 expression. tissue_expression_ns hsa-mir-30c Ovarian Neoplasms 28423547 Genomic imbalances are involved in miR-30c and let-7a deregulation in ovarian tumors: implications for HMGA2 expression. tissue_expression_ns hsa-mir-20a Toxoplasma gondii Infection 28424428 Global miRNA expression profiling of domestic cat livers following acute Toxoplasma gondii infection. tissue_expression_ns hsa-mir-132 "Carcinoma, Hepatocellular" 28430373 A five-miRNA expression signature predicts survival in hepatocellular carcinoma. tissue_expression_ns hsa-mir-1468 "Carcinoma, Hepatocellular" 28430373 A five-miRNA expression signature predicts survival in hepatocellular carcinoma. tissue_expression_ns hsa-mir-212 "Carcinoma, Hepatocellular" 28430373 A five-miRNA expression signature predicts survival in hepatocellular carcinoma. tissue_expression_ns hsa-mir-301a "Carcinoma, Hepatocellular" 28430373 A five-miRNA expression signature predicts survival in hepatocellular carcinoma. tissue_expression_ns hsa-mir-489 "Carcinoma, Hepatocellular" 28430373 A five-miRNA expression signature predicts survival in hepatocellular carcinoma. tissue_expression_ns hsa-let-7a "Carcinoma, Hepatocellular" 28440732 Expression of microRNA let-7a positively correlates with hepatitis B virus replication in hepatocellular carcinoma tissues. tissue_expression_ns hsa-mir-150 Myeloma 28458781 MicroRNA expression patterns and target prediction in multiple myeloma development and malignancy. tissue_expression_ns hsa-mir-21 Infection [unspecific] 28472924 Identification of differentially expressed Atlantic salmon miRNAs responding to salmonid alphavirus (SAV) infection. tissue_expression_ns hsa-mir-452 "Adenocarcinoma, Lung" 28488527 Clinical value of miR-452-5p expression in lung adenocarcinoma: A retrospective quantitative real-time polymerase chain reaction study and verification based on The Cancer Genome Atlas and Gene Expression Omnibus databases. tissue_expression_ns hsa-mir-10a "Squamous Cell Carcinoma, Head and Neck" 28495058 miRNA profiling of primary lung and head and neck squamous cell carcinomas: Addressing a diagnostic dilemma. tissue_expression_ns hsa-mir-10b "Squamous Cell Carcinoma, Head and Neck" 28495058 miRNA profiling of primary lung and head and neck squamous cell carcinomas: Addressing a diagnostic dilemma. tissue_expression_ns hsa-mir-34a "Squamous Cell Carcinoma, Head and Neck" 28495058 miRNA profiling of primary lung and head and neck squamous cell carcinomas: Addressing a diagnostic dilemma. tissue_expression_ns hsa-mir-140 Thymoma 28517980 "Among the seven significant miRNAs, six (mir-140, mir-450b, mir-542, mir-639, mir-3613 and mir-3913¨C1) were positively associated with OS, while the remaining one (mir-1976) was negatively correlated" tissue_expression_ns hsa-mir-1976 Thymoma 28517980 "Among the seven significant miRNAs, six (mir-140, mir-450b, mir-542, mir-639, mir-3613 and mir-3913¨C1) were positively associated with OS, while the remaining one (mir-1976) was negatively correlated" tissue_expression_ns hsa-mir-3613 Thymoma 28517980 "Among the seven significant miRNAs, six (mir-140, mir-450b, mir-542, mir-639, mir-3613 and mir-3913¨C1) were positively associated with OS, while the remaining one (mir-1976) was negatively correlated" tissue_expression_ns hsa-mir-3913 Thymoma 28517980 "Among the seven significant miRNAs, six (mir-140, mir-450b, mir-542, mir-639, mir-3613 and mir-3913¨C1) were positively associated with OS, while the remaining one (mir-1976) was negatively correlated" tissue_expression_ns hsa-mir-450b Thymoma 28517980 "Among the seven significant miRNAs, six (mir-140, mir-450b, mir-542, mir-639, mir-3613 and mir-3913¨C1) were positively associated with OS, while the remaining one (mir-1976) was negatively correlated" tissue_expression_ns hsa-mir-542 Thymoma 28517980 "Among the seven significant miRNAs, six (mir-140, mir-450b, mir-542, mir-639, mir-3613 and mir-3913¨C1) were positively associated with OS, while the remaining one (mir-1976) was negatively correlated" tissue_expression_ns hsa-mir-639 Thymoma 28517980 "Among the seven significant miRNAs, six (mir-140, mir-450b, mir-542, mir-639, mir-3613 and mir-3913¨C1) were positively associated with OS, while the remaining one (mir-1976) was negatively correlated" tissue_expression_ns hsa-let-7b "Carcinoma, Lung, Non-Small-Cell" 28534369 "The relationship between miR-17-5p, miR-92a, and let-7b expression with non-small cell lung cancer targeted drug resistance." tissue_expression_ns hsa-mir-17 "Carcinoma, Lung, Non-Small-Cell" 28534369 "The relationship between miR-17-5p, miR-92a, and let-7b expression with non-small cell lung cancer targeted drug resistance." tissue_expression_ns hsa-mir-92a "Carcinoma, Lung, Non-Small-Cell" 28534369 "The relationship between miR-17-5p, miR-92a, and let-7b expression with non-small cell lung cancer targeted drug resistance." tissue_expression_ns hsa-mir-126 Neoplasms [unspecific] 28536479 Circulating microRNA-214 and -126 as potential biomarkers for canine neoplastic disease. tissue_expression_ns hsa-mir-214 Neoplasms [unspecific] 28536479 Circulating microRNA-214 and -126 as potential biomarkers for canine neoplastic disease. tissue_expression_ns hsa-mir-15a "Carcinoma, Lung, Non-Small-Cell" 28537679 MiR-15a expression analysis in non-small cell lung cancer A549 cells under local hypoxia microenvironment. tissue_expression_ns hsa-mir-217 "Adenocarcinoma, Pancreatic Ductal" 28539816 hsa-miR-96 and hsa-miR-217 Expression Down-Regulates with Increasing Dysplasia in Pancreatic Intraepithelial Neoplasias and Intraductal Papillary Mucinous Neoplasms. tissue_expression_ns hsa-mir-96 "Adenocarcinoma, Pancreatic Ductal" 28539816 hsa-miR-96 and hsa-miR-217 Expression Down-Regulates with Increasing Dysplasia in Pancreatic Intraepithelial Neoplasias and Intraductal Papillary Mucinous Neoplasms. tissue_expression_ns hsa-mir-29b Parkinson Disease 28540642 Plasma and White Blood Cells Show Different miRNA Expression Profiles in Parkinson's Disease. tissue_expression_ns hsa-mir-30a Parkinson Disease 28540642 Plasma and White Blood Cells Show Different miRNA Expression Profiles in Parkinson's Disease. tissue_expression_ns hsa-mir-21 Glioma 28547591 MicroRNA-21 expression in the prognosis of low-grade gliomas: data from the cancer genome atlas (TCGA) project. tissue_expression_ns hsa-mir-200b Pancreatic Neoplasms 28548126 MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer. tissue_expression_ns hsa-mir-200c Pancreatic Neoplasms 28548126 MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer. tissue_expression_ns hsa-mir-21 Pancreatic Neoplasms 28548126 MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer. tissue_expression_ns hsa-mir-210 Pancreatic Neoplasms 28548126 MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer. tissue_expression_ns hsa-mir-106a "Carcinoma, Colon" 28571588 Expression profiling indicating low selenium-sensitive microRNA levels linked to cell cycle and cell stress response pathways in the CaCo-2 cell line. tissue_expression_ns hsa-mir-200c "Carcinoma, Colon" 28571588 Expression profiling indicating low selenium-sensitive microRNA levels linked to cell cycle and cell stress response pathways in the CaCo-2 cell line. tissue_expression_ns hsa-mir-205 "Carcinoma, Colon" 28571588 Expression profiling indicating low selenium-sensitive microRNA levels linked to cell cycle and cell stress response pathways in the CaCo-2 cell line. tissue_expression_ns hsa-mir-302d "Carcinoma, Colon" 28571588 Expression profiling indicating low selenium-sensitive microRNA levels linked to cell cycle and cell stress response pathways in the CaCo-2 cell line. tissue_expression_ns hsa-mir-373 "Carcinoma, Colon" 28571588 Expression profiling indicating low selenium-sensitive microRNA levels linked to cell cycle and cell stress response pathways in the CaCo-2 cell line. tissue_expression_ns hsa-mir-4454 "Carcinoma, Colon" 28571588 Expression profiling indicating low selenium-sensitive microRNA levels linked to cell cycle and cell stress response pathways in the CaCo-2 cell line. tissue_expression_ns hsa-mir-483 "Carcinoma, Colon" 28571588 Expression profiling indicating low selenium-sensitive microRNA levels linked to cell cycle and cell stress response pathways in the CaCo-2 cell line. tissue_expression_ns hsa-mir-512 "Carcinoma, Colon" 28571588 Expression profiling indicating low selenium-sensitive microRNA levels linked to cell cycle and cell stress response pathways in the CaCo-2 cell line. tissue_expression_ns hsa-mir-93 "Carcinoma, Colon" 28571588 Expression profiling indicating low selenium-sensitive microRNA levels linked to cell cycle and cell stress response pathways in the CaCo-2 cell line. tissue_expression_ns hsa-mir-99b "Carcinoma, Colon" 28571588 Expression profiling indicating low selenium-sensitive microRNA levels linked to cell cycle and cell stress response pathways in the CaCo-2 cell line. tissue_expression_ns hsa-mir-1178 "Carcinoma, Pancreatic" 28592083 Correlation between miR-1178 expression and clinicopathological significance in human pancreatic cancer. tissue_expression_ns hsa-mir-146b "Carcinoma, Thyroid, Papillary" 28599426 Dynamic monitoring of circulating microRNAs as a predictive biomarker for the diagnosis and recurrence of papillary thyroid carcinoma. tissue_expression_ns hsa-mir-221 "Carcinoma, Thyroid, Papillary" 28599426 Dynamic monitoring of circulating microRNAs as a predictive biomarker for the diagnosis and recurrence of papillary thyroid carcinoma. tissue_expression_ns hsa-mir-183 "Carcinoma, Tounge" 28616749 miR-183 and miR-21 expression as biomarkers of progression and survival in tongue carcinoma patients. tissue_expression_ns hsa-mir-21 "Carcinoma, Tounge" 28616749 miR-183 and miR-21 expression as biomarkers of progression and survival in tongue carcinoma patients. tissue_expression_ns hsa-mir-145 "Carcinoma, Prostate" 28617988 MiR-145 detection in urinary extracellular vesicles increase diagnostic efficiency of prostate cancer based on hydrostatic filtration dialysis method. tissue_expression_ns hsa-mir-7 "Adenocarcinoma, Lung" 28618418 Prognostic Significance of microRNA-7 and its Roles in the Regulation of Cisplatin Resistance in Lung Adenocarcinoma. tissue_expression_ns hsa-mir-375 Colorectal Carcinoma 28618945 "The expression profiling of serum miR-92a, miR-375, and miR-760 in colorectal cancer: An Egyptian study." tissue_expression_ns hsa-mir-760 Colorectal Carcinoma 28618945 "The expression profiling of serum miR-92a, miR-375, and miR-760 in colorectal cancer: An Egyptian study." tissue_expression_ns hsa-mir-92a Colorectal Carcinoma 28618945 "The expression profiling of serum miR-92a, miR-375, and miR-760 in colorectal cancer: An Egyptian study." tissue_expression_ns hsa-mir-127 Prostate Neoplasms 28621736 A Panel of MicroRNAs as Diagnostic Biomarkers for the Identification of Prostate Cancer. tissue_expression_ns hsa-mir-21 Gastric Neoplasms 28628924 Chrysin Alters microRNAs Expression Levels in Gastric Cancer Cells: Possible Molecular Mechanism. tissue_expression_ns hsa-mir-221 Gastric Neoplasms 28628924 Chrysin Alters microRNAs Expression Levels in Gastric Cancer Cells: Possible Molecular Mechanism. tissue_expression_ns hsa-mir-34a Gastric Neoplasms 28628924 Chrysin Alters microRNAs Expression Levels in Gastric Cancer Cells: Possible Molecular Mechanism. tissue_expression_ns hsa-let-7a "Carcinoma, Thyroid" 28655518 Effects of long non-coding RNA H19 and microRNA let7a expression on thyroid cancer prognosis. tissue_expression_ns hsa-mir-133b Glioma 28675056 MicroRNA-133b expression associates with clinicopathological features and prognosis in glioma. tissue_expression_ns hsa-mir-29a Acquired Immunodeficiency Syndrome 28692540 Unique microRNA expression in the colonic mucosa during chronic HIV-1 infection. tissue_expression_ns hsa-let-7a "Carcinoma, Renal Cell, Clear-Cell" 28694731 Detection of let-7 miRNAs in urine supernatant as potential diagnostic approach in non-metastatic clear-cell renal cell carcinoma. tissue_expression_ns hsa-let-7b "Carcinoma, Renal Cell, Clear-Cell" 28694731 Detection of let-7 miRNAs in urine supernatant as potential diagnostic approach in non-metastatic clear-cell renal cell carcinoma. tissue_expression_ns hsa-let-7d "Carcinoma, Renal Cell, Clear-Cell" 28694731 Detection of let-7 miRNAs in urine supernatant as potential diagnostic approach in non-metastatic clear-cell renal cell carcinoma. tissue_expression_ns hsa-let-7e "Carcinoma, Renal Cell, Clear-Cell" 28694731 Detection of let-7 miRNAs in urine supernatant as potential diagnostic approach in non-metastatic clear-cell renal cell carcinoma. tissue_expression_ns hsa-let-7g "Carcinoma, Renal Cell, Clear-Cell" 28694731 Detection of let-7 miRNAs in urine supernatant as potential diagnostic approach in non-metastatic clear-cell renal cell carcinoma. tissue_expression_ns hsa-mir-126 "Carcinoma, Colon" 28714375 "The association of miR-126-3p, miR-126-5p and miR-664-3p expression profiles with outcomes of patients with metastatic colorectal cancer treated with bevacizumab." tissue_expression_ns hsa-mir-664 "Carcinoma, Colon" 28714375 "The association of miR-126-3p, miR-126-5p and miR-664-3p expression profiles with outcomes of patients with metastatic colorectal cancer treated with bevacizumab." tissue_expression_ns hsa-mir-146a Down Syndrome 28720071 Developmental Expression and Dysregulation of miR-146a and miR-155 in Down's Syndrome and Mouse Models of Down's Syndrome and Alzheimer's Disease. tissue_expression_ns hsa-mir-155 Down Syndrome 28720071 Developmental Expression and Dysregulation of miR-146a and miR-155 in Down's Syndrome and Mouse Models of Down's Syndrome and Alzheimer's Disease. tissue_expression_ns hsa-mir-204 "Carcinoma, Hepatocellular" 28746200 Promising significance of the association of miR-204-5p expression with clinicopathological features of hepatocellular carcinoma tissue_expression_ns hsa-mir-130b Penis Carcinoma 28751665 "hsa-miR-31, hsa-miR-34a and hsa-miR-130b, were significantly associated with over-represented pathways in cancer" tissue_expression_ns hsa-mir-31 Penis Carcinoma 28751665 "hsa-miR-31, hsa-miR-34a and hsa-miR-130b, were significantly associated with over-represented pathways in cancer" tissue_expression_ns hsa-mir-34a Penis Carcinoma 28751665 "hsa-miR-31, hsa-miR-34a and hsa-miR-130b, were significantly associated with over-represented pathways in cancer" tissue_expression_ns hsa-mir-29b Heart Failure 28765595 Integration of miRNA and mRNA expression profiles reveals microRNA-regulated networks during muscle wasting in cardiac cachexia. tissue_expression_ns hsa-mir-145 Irritable Bowel Syndrome 28774781 "In all studied IBS samples disturbances in expression of cytokines IL-6, IL-10 and TNF-¦Á as well as miR-145, miR-148-5p and miR-592 were observed" tissue_expression_ns hsa-mir-148 Irritable Bowel Syndrome 28774781 "In all studied IBS samples disturbances in expression of cytokines IL-6, IL-10 and TNF-¦Á as well as miR-145, miR-148-5p and miR-592 were observed" tissue_expression_ns hsa-mir-592 Irritable Bowel Syndrome 28774781 "In all studied IBS samples disturbances in expression of cytokines IL-6, IL-10 and TNF-¦Á as well as miR-145, miR-148-5p and miR-592 were observed" tissue_expression_ns hsa-mir-129 Sertoli Cell-Only Syndrome 28779347 "Among the highest differentially expressed miRNAs only seven, hsa-miR-34b, hsa-miR-34b*, hsa-miR-34c-5p, hsa-miR-449a, hsa-miR-449b*, hsa-miR-517b, and hsa-miR-129-3p, were shared by the three histopathological conditions and were strongly downregulated compared to the normal group " tissue_expression_ns hsa-mir-34b Sertoli Cell-Only Syndrome 28779347 "Among the highest differentially expressed miRNAs only seven, hsa-miR-34b, hsa-miR-34b*, hsa-miR-34c-5p, hsa-miR-449a, hsa-miR-449b*, hsa-miR-517b, and hsa-miR-129-3p, were shared by the three histopathological conditions and were strongly downregulated compared to the normal group " tissue_expression_ns hsa-mir-34c Sertoli Cell-Only Syndrome 28779347 "Among the highest differentially expressed miRNAs only seven, hsa-miR-34b, hsa-miR-34b*, hsa-miR-34c-5p, hsa-miR-449a, hsa-miR-449b*, hsa-miR-517b, and hsa-miR-129-3p, were shared by the three histopathological conditions and were strongly downregulated compared to the normal group " tissue_expression_ns hsa-mir-449a Sertoli Cell-Only Syndrome 28779347 "Among the highest differentially expressed miRNAs only seven, hsa-miR-34b, hsa-miR-34b*, hsa-miR-34c-5p, hsa-miR-449a, hsa-miR-449b*, hsa-miR-517b, and hsa-miR-129-3p, were shared by the three histopathological conditions and were strongly downregulated compared to the normal group " tissue_expression_ns hsa-mir-449b Sertoli Cell-Only Syndrome 28779347 "Among the highest differentially expressed miRNAs only seven, hsa-miR-34b, hsa-miR-34b*, hsa-miR-34c-5p, hsa-miR-449a, hsa-miR-449b*, hsa-miR-517b, and hsa-miR-129-3p, were shared by the three histopathological conditions and were strongly downregulated compared to the normal group " tissue_expression_ns hsa-mir-517b Sertoli Cell-Only Syndrome 28779347 "Among the highest differentially expressed miRNAs only seven, hsa-miR-34b, hsa-miR-34b*, hsa-miR-34c-5p, hsa-miR-449a, hsa-miR-449b*, hsa-miR-517b, and hsa-miR-129-3p, were shared by the three histopathological conditions and were strongly downregulated compared to the normal group " tissue_expression_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 28799568 Association of long non-coding RNA H19 and microRNA-21 expression with the biological features and prognosis of non-small cell lung cancer. tissue_expression_ns hsa-mir-21 Cardiovascular Diseases [unspecific] 28802862 MicroRNA-21: Expression in oligodendrocytes and correlation with low myelin mRNAs in depression and alcoholism. tissue_expression_ns hsa-mir-223 Mastitis 28831974 Expression profiles of miRNAs from bovine mammary glands in response to Streptococcus agalactiae-induced mastitis. tissue_expression_ns hsa-mir-375 "Carcinoma, Thyroid, Medullary" 28861609 MiR-375 and YAP1 expression profiling in medullary thyroid carcinoma and their correlation with clinical-pathological features and outcome. tissue_expression_ns hsa-mir-10b Neoplasms [unspecific] 28864233 MicroRNA-10b and the clinical outcomes of various cancers: A systematic review and meta-analysis. tissue_expression_ns hsa-mir-125a "Carcinoma, Hepatocellular" 28878257 Molecular mechanisms governing microRNA-125a expression in human hepatocellular carcinoma cells. tissue_expression_ns hsa-mir-155 Breast Neoplasms 28882698 Prognostic value of microRNA-9 and microRNA-155 expression in triple-negative breast cancer tissue_expression_ns hsa-mir-9 Breast Neoplasms 28882698 Prognostic value of microRNA-9 and microRNA-155 expression in triple-negative breast cancer tissue_expression_ns hsa-mir-34c Infertility 28886318 New insights into the expression profile of MicroRNA-34c and P53 in infertile men spermatozoa and testicular tissue. tissue_expression_ns hsa-mir-145 Pancreatic Adenocarcinoma 28903323 The pancreatic tumor microenvironment drives changes in miRNA expression that promote cytokine production and inhibit migration by the tumor associated stroma. tissue_expression_ns hsa-mir-205 Pancreatic Adenocarcinoma 28903323 The pancreatic tumor microenvironment drives changes in miRNA expression that promote cytokine production and inhibit migration by the tumor associated stroma. tissue_expression_ns hsa-mir-424 Skin Hemangioma 28928430 The expression and function of miR-424 in infantile skin hemangioma and its mechanism. tissue_expression_ns hsa-mir-205 "Carcinoma, Nasopharyngeal" 28931826 MicroRNA profiling study reveals miR-150 in association with metastasis in nasopharyngeal carcinoma tissue_expression_ns hsa-mir-34a "Carcinoma, Hepatocellular" 28950684 Deregulation of miR-34a and Its Chaperon Hsp70 in Hepatitis C virus-Induced Liver Cirrhosis and Hepatocellular Carcinoma Patients tissue_expression_ns hsa-mir-200c "Squamous Cell Carcinoma, Sinonasal" 28960576 Deregulation of selected microRNAs in sinonasal carcinoma: Value of miR-21 as prognostic biomarker in sinonasal squamous cell carcinoma. tissue_expression_ns hsa-mir-21 "Squamous Cell Carcinoma, Sinonasal" 28960576 Deregulation of selected microRNAs in sinonasal carcinoma: Value of miR-21 as prognostic biomarker in sinonasal squamous cell carcinoma. tissue_expression_ns hsa-mir-125b "Carcinoma, Hepatocellular" 28984009 MicroRNA-125b expression and intrahepatic metastasis are predictors for early recurrence after hepatocellular carcinoma resection. tissue_expression_ns hsa-mir-181a African Swine Fever 29041944 Differential expression of porcine microRNAs in African swine fever virus infected pigs: a proof-of-concept study. tissue_expression_ns hsa-mir-21 Pancreatic Adenocarcinoma 29069873 These molecules are often aberrantly expressed and exhibit oncogenic and/or tumor suppressor functions in PDAC tissue_expression_ns hsa-mir-143 Breast Neoplasms 29073169 Expression and function of the miR-143/145 cluster in vitro and in vivo in human breast cancer. tissue_expression_ns hsa-mir-145 Breast Neoplasms 29073169 Expression and function of the miR-143/145 cluster in vitro and in vivo in human breast cancer. tissue_expression_ns hsa-let-7a "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 29082244 "Expression Levels and Clinical Significance of miR-21-5p, miR-let-7a, and miR-34c-5p in Laryngeal Squamous Cell Carcinoma." tissue_expression_ns hsa-mir-21 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 29082244 "Expression Levels and Clinical Significance of miR-21-5p, miR-let-7a, and miR-34c-5p in Laryngeal Squamous Cell Carcinoma." tissue_expression_ns hsa-mir-34c "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 29082244 "Expression Levels and Clinical Significance of miR-21-5p, miR-let-7a, and miR-34c-5p in Laryngeal Squamous Cell Carcinoma." tissue_expression_ns hsa-mir-1 "Adenocarcinoma, Pancreatic Ductal" 29085459 Abnormal alterations of miR-1 and miR-214 are associated with clinicopathological features and prognosis of patients with PDAC. tissue_expression_ns hsa-mir-214 "Adenocarcinoma, Pancreatic Ductal" 29085459 Abnormal alterations of miR-1 and miR-214 are associated with clinicopathological features and prognosis of patients with PDAC. tissue_expression_ns hsa-mir-203 "Carcinoma, Lung, Non-Small-Cell" 29088807 Identification of microRNA differentially expressed in three subtypes of non-small cell lung cancer and in silico functional analysis. tissue_expression_ns hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 29088807 Identification of microRNA differentially expressed in three subtypes of non-small cell lung cancer and in silico functional analysis. tissue_expression_ns hsa-mir-375 "Carcinoma, Lung, Non-Small-Cell" 29088807 Identification of microRNA differentially expressed in three subtypes of non-small cell lung cancer and in silico functional analysis. tissue_expression_ns hsa-mir-302a "Carcinoma, Mucoepidermoid" 29095552 miRNA expression profile of mucoepidermoid carcinoma. tissue_expression_ns hsa-mir-10b Breast Neoplasms 29113216 miR-10b is a useful marker for predicting metastasis and angiogenesis in ANN breast cancer tissue_expression_ns hsa-mir-372 "Adenocarcinoma, Gastric" 29135097 Analysis of expression profile of miRNA in stomach adenocarcinoma. tissue_expression_ns hsa-mir-143 Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-146a Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-148a Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-150 Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-181a Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-196a Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-210 Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-222 Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-223 Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-23a Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-25 Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-27a Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-30b Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-30c Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-30d Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-31 Colon Neoplasms 29152124 "The LASSO regression analysis identified a 16-miRNA signature including miR-143-5p, miR-27a-3p, miR-31-5p, miR-181a-5p, miR-30b-5p, miR-30d-5p, miR-146a-5p, miR-23a-3p, miR-150-5p, miR-210-3p, miR-25-3p, miR-196a-5p, miR-148a-3p, miR-222-3p, miR-30c-5p and miR-223-3p" tissue_expression_ns hsa-mir-503 Breast Neoplasms 29164842 "miR-503 is expressed in numerous types of tumors such as breast cancer, prostate cancer, lung cancer, colorectal cancer, hepatocellular carcinoma, glioblastoma andseveral others" tissue_expression_ns hsa-mir-503 "Carcinoma, Hepatocellular" 29164842 "miR-503 is expressed in numerous types of tumors such as breast cancer, prostate cancer, lung cancer, colorectal cancer, hepatocellular carcinoma, glioblastoma andseveral others" tissue_expression_ns hsa-mir-503 Colorectal Carcinoma 29164842 "miR-503 is expressed in numerous types of tumors such as breast cancer, prostate cancer, lung cancer, colorectal cancer, hepatocellular carcinoma, glioblastoma andseveral others" tissue_expression_ns hsa-mir-503 Glioblastoma 29164842 "miR-503 is expressed in numerous types of tumors such as breast cancer, prostate cancer, lung cancer, colorectal cancer, hepatocellular carcinoma, glioblastoma andseveral others" tissue_expression_ns hsa-mir-503 Lung Neoplasms 29164842 "miR-503 is expressed in numerous types of tumors such as breast cancer, prostate cancer, lung cancer, colorectal cancer, hepatocellular carcinoma, glioblastoma andseveral others" tissue_expression_ns hsa-mir-503 Prostate Neoplasms 29164842 "miR-503 is expressed in numerous types of tumors such as breast cancer, prostate cancer, lung cancer, colorectal cancer, hepatocellular carcinoma, glioblastoma andseveral others" tissue_expression_ns hsa-mir-106b "Carcinoma, Hepatocellular" 29179453 MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis tissue_expression_ns hsa-mir-126 "Carcinoma, Renal Cell, Clear-Cell" 29202733 Expression of micro-RNAs and genes related to angiogenesis in ccRCC and associations with tumor characteristics tissue_expression_ns hsa-mir-200b "Carcinoma, Renal Cell, Clear-Cell" 29202733 Expression of micro-RNAs and genes related to angiogenesis in ccRCC and associations with tumor characteristics tissue_expression_ns hsa-let-7a Periodontitis 29226952 "Differential expression of microRNAs let-7a, miR-125b, miR-100, and miR-21 and interaction with NF-kB pathway genes in periodontitis pathogenesis" tissue_expression_ns hsa-mir-100 Periodontitis 29226952 "Differential expression of microRNAs let-7a, miR-125b, miR-100, and miR-21 and interaction with NF-kB pathway genes in periodontitis pathogenesis" tissue_expression_ns hsa-mir-125b Periodontitis 29226952 "Differential expression of microRNAs let-7a, miR-125b, miR-100, and miR-21 and interaction with NF-kB pathway genes in periodontitis pathogenesis" tissue_expression_ns hsa-mir-21 Periodontitis 29226952 "Differential expression of microRNAs let-7a, miR-125b, miR-100, and miR-21 and interaction with NF-kB pathway genes in periodontitis pathogenesis" tissue_expression_ns hsa-mir-155 "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" tissue_expression_ns hsa-mir-199a "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" tissue_expression_ns hsa-mir-200a "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" tissue_expression_ns hsa-mir-203 "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" tissue_expression_ns hsa-mir-22 "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" tissue_expression_ns hsa-mir-221 "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" tissue_expression_ns hsa-mir-29c "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" tissue_expression_ns hsa-mir-34a "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" tissue_expression_ns hsa-mir-34c "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" tissue_expression_ns hsa-mir-9 "Carcinoma, Hepatocellular" 29291025 "tissue miR-9, miR-21, miR-22, miR-29c, miR-34a, miR-34c, miR-155, miR-199a, miR-200a, miR-203, miR-221 and blood miR-21, miR-148a, miR-192, miR-224 demonstrate significantly prognostic value" tissue_expression_ns hsa-mir-103a Vulvar Squamous Tumor 29299981 "Expression levels of six microRNAs-hsa-miR-425-5p, hsa-miR-191-5p, hsa-miR-93-5p, hsa-miR-423-5p, hsa-miR-103a-3p, and hsa-miR-16-5p-were analyzed by quantitative reverse transcription polymerase chain reaction in plasma samples" tissue_expression_ns hsa-mir-16 Vulvar Squamous Tumor 29299981 "Expression levels of six microRNAs-hsa-miR-425-5p, hsa-miR-191-5p, hsa-miR-93-5p, hsa-miR-423-5p, hsa-miR-103a-3p, and hsa-miR-16-5p-were analyzed by quantitative reverse transcription polymerase chain reaction in plasma samples" tissue_expression_ns hsa-mir-191 Vulvar Squamous Tumor 29299981 "Expression levels of six microRNAs-hsa-miR-425-5p, hsa-miR-191-5p, hsa-miR-93-5p, hsa-miR-423-5p, hsa-miR-103a-3p, and hsa-miR-16-5p-were analyzed by quantitative reverse transcription polymerase chain reaction in plasma samples" tissue_expression_ns hsa-mir-423 Vulvar Squamous Tumor 29299981 "Expression levels of six microRNAs-hsa-miR-425-5p, hsa-miR-191-5p, hsa-miR-93-5p, hsa-miR-423-5p, hsa-miR-103a-3p, and hsa-miR-16-5p-were analyzed by quantitative reverse transcription polymerase chain reaction in plasma samples" tissue_expression_ns hsa-mir-425 Vulvar Squamous Tumor 29299981 "Expression levels of six microRNAs-hsa-miR-425-5p, hsa-miR-191-5p, hsa-miR-93-5p, hsa-miR-423-5p, hsa-miR-103a-3p, and hsa-miR-16-5p-were analyzed by quantitative reverse transcription polymerase chain reaction in plasma samples" tissue_expression_ns hsa-mir-93 Vulvar Squamous Tumor 29299981 "Expression levels of six microRNAs-hsa-miR-425-5p, hsa-miR-191-5p, hsa-miR-93-5p, hsa-miR-423-5p, hsa-miR-103a-3p, and hsa-miR-16-5p-were analyzed by quantitative reverse transcription polymerase chain reaction in plasma samples" tissue_expression_ns hsa-let-7c Mitral Valve Disease 29315310 "Dysregulation of valvular interstitial cell let-7c, miR-17, miR-20a, and miR-30d in naturally occurring canine myxomatous mitral valve disease" tissue_expression_ns hsa-mir-17 Mitral Valve Disease 29315310 "Dysregulation of valvular interstitial cell let-7c, miR-17, miR-20a, and miR-30d in naturally occurring canine myxomatous mitral valve disease" tissue_expression_ns hsa-mir-20a Mitral Valve Disease 29315310 "Dysregulation of valvular interstitial cell let-7c, miR-17, miR-20a, and miR-30d in naturally occurring canine myxomatous mitral valve disease" tissue_expression_ns hsa-mir-30d Mitral Valve Disease 29315310 "Dysregulation of valvular interstitial cell let-7c, miR-17, miR-20a, and miR-30d in naturally occurring canine myxomatous mitral valve disease" tissue_expression_ns hsa-mir-186 Acute Peritonitis 29360196 "The data from the current study provide novel evidence of the differential expression of miRNAs in ascites from patients with PCA and SBP, which may offer an additional miRNA-based molecular approach for the differential diagnosis of PCA" tissue_expression_ns hsa-mir-186 Peritoneal Neoplasms 29360196 "The data from the current study provide novel evidence of the differential expression of miRNAs in ascites from patients with PCA and SBP, which may offer an additional miRNA-based molecular approach for the differential diagnosis of PCA" tissue_expression_ns hsa-mir-21 Acute Peritonitis 29360196 "The data from the current study provide novel evidence of the differential expression of miRNAs in ascites from patients with PCA and SBP, which may offer an additional miRNA-based molecular approach for the differential diagnosis of PCA" tissue_expression_ns hsa-mir-21 Peritoneal Neoplasms 29360196 "The data from the current study provide novel evidence of the differential expression of miRNAs in ascites from patients with PCA and SBP, which may offer an additional miRNA-based molecular approach for the differential diagnosis of PCA" tissue_expression_ns hsa-mir-222 Acute Peritonitis 29360196 "The data from the current study provide novel evidence of the differential expression of miRNAs in ascites from patients with PCA and SBP, which may offer an additional miRNA-based molecular approach for the differential diagnosis of PCA" tissue_expression_ns hsa-mir-222 Peritoneal Neoplasms 29360196 "The data from the current study provide novel evidence of the differential expression of miRNAs in ascites from patients with PCA and SBP, which may offer an additional miRNA-based molecular approach for the differential diagnosis of PCA" tissue_expression_ns hsa-mir-223 Acute Peritonitis 29360196 "The data from the current study provide novel evidence of the differential expression of miRNAs in ascites from patients with PCA and SBP, which may offer an additional miRNA-based molecular approach for the differential diagnosis of PCA" tissue_expression_ns hsa-mir-223 Peritoneal Neoplasms 29360196 "The data from the current study provide novel evidence of the differential expression of miRNAs in ascites from patients with PCA and SBP, which may offer an additional miRNA-based molecular approach for the differential diagnosis of PCA" tissue_expression_ns hsa-mir-483 Acute Peritonitis 29360196 "The data from the current study provide novel evidence of the differential expression of miRNAs in ascites from patients with PCA and SBP, which may offer an additional miRNA-based molecular approach for the differential diagnosis of PCA" tissue_expression_ns hsa-mir-483 Peritoneal Neoplasms 29360196 "The data from the current study provide novel evidence of the differential expression of miRNAs in ascites from patients with PCA and SBP, which may offer an additional miRNA-based molecular approach for the differential diagnosis of PCA" tissue_expression_ns hsa-let-7a Chronic Obstructive Pulmonary Disease 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-let-7a Lung Neoplasms 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-let-7c Chronic Obstructive Pulmonary Disease 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-let-7c Lung Neoplasms 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-126 Chronic Obstructive Pulmonary Disease 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-126 Lung Neoplasms 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-155 Chronic Obstructive Pulmonary Disease 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-155 Lung Neoplasms 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-200b Chronic Obstructive Pulmonary Disease 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-200b Lung Neoplasms 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-21 Chronic Obstructive Pulmonary Disease 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-21 Lung Neoplasms 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-210 Chronic Obstructive Pulmonary Disease 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-210 Lung Neoplasms 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-30a Chronic Obstructive Pulmonary Disease 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-30a Lung Neoplasms 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-451 Chronic Obstructive Pulmonary Disease 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-451 Lung Neoplasms 29371906 Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions tissue_expression_ns hsa-mir-135a Pituitary Adenoma 29374071 "elevant compensatory mechanisms were found through the changes in miR involved in osteoblastogenesis (miR-210-5p, miR-135a-5p, miR-211, miR-23a-3p, miR-204-5p)" tissue_expression_ns hsa-mir-204 Pituitary Adenoma 29374071 "elevant compensatory mechanisms were found through the changes in miR involved in osteoblastogenesis (miR-210-5p, miR-135a-5p, miR-211, miR-23a-3p, miR-204-5p)" tissue_expression_ns hsa-mir-210 Pituitary Adenoma 29374071 "elevant compensatory mechanisms were found through the changes in miR involved in osteoblastogenesis (miR-210-5p, miR-135a-5p, miR-211, miR-23a-3p, miR-204-5p)" tissue_expression_ns hsa-mir-2110 Pituitary Adenoma 29374071 "elevant compensatory mechanisms were found through the changes in miR involved in osteoblastogenesis (miR-210-5p, miR-135a-5p, miR-211, miR-23a-3p, miR-204-5p)" tissue_expression_ns hsa-mir-23a Pituitary Adenoma 29374071 "elevant compensatory mechanisms were found through the changes in miR involved in osteoblastogenesis (miR-210-5p, miR-135a-5p, miR-211, miR-23a-3p, miR-204-5p)" tissue_expression_ns hsa-mir-200 "Squamous Cell Carcinoma, Oral" 29375721 Dysregulation of miR-200 family microRNAs and epithelial-mesenchymal transition markers in oral squamous cell carcinoma tissue_expression_ns hsa-mir-15b Ovarian Disease 29377183 "miR-379, miR-15b, miR-691, miR-872 and miR-1897-5p are potentially useful markers of ovarian toxicity and dysfunction" tissue_expression_ns hsa-mir-1897 Ovarian Disease 29377183 "miR-379, miR-15b, miR-691, miR-872 and miR-1897-5p are potentially useful markers of ovarian toxicity and dysfunction" tissue_expression_ns hsa-mir-379 Ovarian Disease 29377183 "miR-379, miR-15b, miR-691, miR-872 and miR-1897-5p are potentially useful markers of ovarian toxicity and dysfunction" tissue_expression_ns hsa-mir-691 Ovarian Disease 29377183 "miR-379, miR-15b, miR-691, miR-872 and miR-1897-5p are potentially useful markers of ovarian toxicity and dysfunction" tissue_expression_ns hsa-mir-872 Ovarian Disease 29377183 "miR-379, miR-15b, miR-691, miR-872 and miR-1897-5p are potentially useful markers of ovarian toxicity and dysfunction" tissue_expression_ns hsa-let-7b Ovarian Neoplasms 29385306 "RT-PCR revealed a significantly increased expression of ovarian miRNAs (let-7b, miR-17-5p miR-181a, and miR-151), which inhibit follicular granulosa cell proliferation" tissue_expression_ns hsa-mir-151 Ovarian Neoplasms 29385306 "RT-PCR revealed a significantly increased expression of ovarian miRNAs (let-7b, miR-17-5p miR-181a, and miR-151), which inhibit follicular granulosa cell proliferation" tissue_expression_ns hsa-mir-17 Ovarian Neoplasms 29385306 "RT-PCR revealed a significantly increased expression of ovarian miRNAs (let-7b, miR-17-5p miR-181a, and miR-151), which inhibit follicular granulosa cell proliferation" tissue_expression_ns hsa-mir-181a Ovarian Neoplasms 29385306 "RT-PCR revealed a significantly increased expression of ovarian miRNAs (let-7b, miR-17-5p miR-181a, and miR-151), which inhibit follicular granulosa cell proliferation" tissue_expression_ns hsa-mir-10b "Carcinoma, Thyroid, Anaplastic" 29397781 "These results demonstrate that IR deregulates microRNA expression, affecting the double-strand DNA breaks repair efficiency of irradiated thyroid cells, and suggest that miR-10b-5p overexpression may be an innovative approach for anaplastic thyroid cancer therapy by increasing cancer cell radiosensitivity." tissue_expression_ns hsa-mir-146a Diabetic Peripheral Neuropathy 29398906 "miR-146a is involved in the pathogenesis of DPN, and its expression level is closely related to the inflammatory responses that aggravate sciatic nerve injuries" tissue_expression_ns hsa-mir-200b "Carcinoma, Renal Cell" 29416756 "miR-126, miR-222 and miR-200b were significantly differentially expressed between the subtypes by in situ hybridization" tissue_expression_ns hsa-mir-221 "Carcinoma, Renal Cell" 29416756 "miR-126, miR-222 and miR-201b were significantly differentially expressed between the subtypes by in situ hybridization" tissue_expression_ns hsa-mir-222 "Carcinoma, Renal Cell" 29416756 "miR-126, miR-222 and miR-202b were significantly differentially expressed between the subtypes by in situ hybridization" tissue_expression_ns hsa-mir-29b "Carcinoma, Breast" 29422258 miR-29b levels constitute a promising biomarker of favorable prognosis for patients with invasive ductal breast carcinoma tissue_expression_ns hsa-mir-195 Adrenal Cortex Neoplasms 29429354 "Several tissue microRNAs, such as miR-483-5p, miR-503, miR-210, miR-335 and miR-195 were found to be differentially expressed among benign and malignant adrenocortical tumours" tissue_expression_ns hsa-mir-210 Adrenal Cortex Neoplasms 29429354 "Several tissue microRNAs, such as miR-483-5p, miR-503, miR-210, miR-335 and miR-195 were found to be differentially expressed among benign and malignant adrenocortical tumours" tissue_expression_ns hsa-mir-335 Adrenal Cortex Neoplasms 29429354 "Several tissue microRNAs, such as miR-483-5p, miR-503, miR-210, miR-335 and miR-195 were found to be differentially expressed among benign and malignant adrenocortical tumours" tissue_expression_ns hsa-mir-483 Adrenal Cortex Neoplasms 29429354 "Several tissue microRNAs, such as miR-483-5p, miR-503, miR-210, miR-335 and miR-195 were found to be differentially expressed among benign and malignant adrenocortical tumours" tissue_expression_ns hsa-mir-503 Adrenal Cortex Neoplasms 29429354 "Several tissue microRNAs, such as miR-483-5p, miR-503, miR-210, miR-335 and miR-195 were found to be differentially expressed among benign and malignant adrenocortical tumours" tissue_expression_ns hsa-mir-222 "Carcinoma, Thyroid, Papillary" 29435194 miRNA dysregulation and the risk of metastasis and invasion in papillary thyroid cancer: a systematic review and meta-analysis tissue_expression_ns hsa-mir-155 Lung Neoplasms 29437031 Underexpression of miR-486-5p but not Overexpression of miR-156 is Associated with Lung Cancer Stages tissue_expression_ns hsa-mir-486 Lung Neoplasms 29437031 Underexpression of miR-486-5p but not Overexpression of miR-155 is Associated with Lung Cancer Stages tissue_expression_ns hsa-mir-126 Parathyroid Carcinoma 29453660 "miR-139, miR-222, miR-30b, miR-517c, and miR-126* were differentially expressed between PCa and PAd." tissue_expression_ns hsa-mir-139 Parathyroid Carcinoma 29453660 The combined analysis of miR-139 and miR-30b may be used as a potential diagnostic strategy for distinguishing Pca from PAd tissue_expression_ns hsa-mir-222 Parathyroid Carcinoma 29453660 "miR-139, miR-222, miR-30b, miR-517c, and miR-126* were differentially expressed between PCa and PAd." tissue_expression_ns hsa-mir-30b Parathyroid Carcinoma 29453660 The combined analysis of miR-139 and miR-31b may be used as a potential diagnostic strategy for distinguishing Pca from PAd tissue_expression_ns hsa-mir-517c Parathyroid Carcinoma 29453660 "miR-139, miR-222, miR-30b, miR-517c, and miR-126* were differentially expressed between PCa and PAd." tissue_expression_ns hsa-let-7i "Carcinoma, Nasopharyngeal" 29455649 "miR-142, miR-26a, miR-141 and let-7i have significant prognostic power" tissue_expression_ns hsa-mir-141 "Carcinoma, Nasopharyngeal" 29455649 "miR-142, miR-26a, miR-141 and let-7i have significant prognostic power" tissue_expression_ns hsa-mir-142 "Carcinoma, Nasopharyngeal" 29455649 "miR-142, miR-26a, miR-141 and let-7i have significant prognostic power" tissue_expression_ns hsa-mir-26a "Carcinoma, Nasopharyngeal" 29455649 "miR-142, miR-26a, miR-141 and let-7i have significant prognostic power" tissue_expression_ns hsa-mir-125b Breast Neoplasms 29483949 Differentially expressed miRNAs provide insights of this uncommon but highly aggressive pathology tissue_expression_ns hsa-mir-101-1 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-124-1 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-129 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-139 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-145 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-149 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-16 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-202 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-21 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-221 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-23a Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-28 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-424 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-520 Multiple Myeloma 29546453 "All these miRNAs were significantly over-expressed in patients vs controls (MIR-16-1, MIR-21, MIR-23A, MIR-28, MIR-101-1, MIR-124-1, MIR-129, MIR-139, MIR-145, MIR-149, MIR-202, MIR-221, MIR-424, MIR-520)" tissue_expression_ns hsa-mir-15a "Carcinoma, Renal Cell" 29549624 MicroRNA-15a expression measured in urine samples as a potential biomarker of renal cell carcinoma. tissue_expression_ns hsa-mir-191 "Carcinoma, Breast" 29555574 "4 miRNAs (miR-191-5p, miR-214-3p, miR-451a, and miR-489) were validated in a total of 159 patients including a training set" tissue_expression_ns hsa-mir-214 "Carcinoma, Breast" 29555574 "4 miRNAs (miR-191-5p, miR-214-3p, miR-451a, and miR-489) were validated in a total of 159 patients including a training set" tissue_expression_ns hsa-mir-451a "Carcinoma, Breast" 29555574 "4 miRNAs (miR-191-5p, miR-214-3p, miR-451a, and miR-489) were validated in a total of 159 patients including a training set" tissue_expression_ns hsa-mir-489 "Carcinoma, Breast" 29555574 "4 miRNAs (miR-191-5p, miR-214-3p, miR-451a, and miR-489) were validated in a total of 159 patients including a training set" tissue_expression_ns hsa-mir-1226 "Carcinoma, Breast" 29557813 whereas miR-342 and miR-1226 may be associated with tamoxifen resistance in breast cancer cells tissue_expression_ns hsa-mir-342 "Carcinoma, Breast" 29557813 whereas miR-342 and miR-1226 may be associated with tamoxifen resistance in breast cancer cells tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 29564561 "The expression levels of miR-7 and -21 were up-regulated in non-granular type of laterally spreading tumor, UCAT, and SSA/P compared with those in polypoid and FAP tumors" tissue_expression_ns hsa-mir-7 Colorectal Carcinoma 29564561 "The expression levels of miR-7 and -21 were up-regulated in non-granular type of laterally spreading tumor, UCAT, and SSA/P compared with those in polypoid and FAP tumors" tissue_expression_ns hsa-mir-142 Uterine Corpus Endometrial Carcinoma 29567372 A six-microRNA signature predicts survival of patients with uterine corpus endometrial carcinoma. tissue_expression_ns hsa-mir-146a Uterine Corpus Endometrial Carcinoma 29567372 A six-microRNA signature predicts survival of patients with uterine corpus endometrial carcinoma. tissue_expression_ns hsa-mir-15a Uterine Corpus Endometrial Carcinoma 29567372 A six-microRNA signature predicts survival of patients with uterine corpus endometrial carcinoma. tissue_expression_ns hsa-mir-1976 Uterine Corpus Endometrial Carcinoma 29567372 A six-microRNA signature predicts survival of patients with uterine corpus endometrial carcinoma. tissue_expression_ns hsa-mir-3170 Uterine Corpus Endometrial Carcinoma 29567372 A six-microRNA signature predicts survival of patients with uterine corpus endometrial carcinoma. tissue_expression_ns hsa-mir-135b Colorectal Carcinoma 29633600 "detection on miR-21, miR-135b, miR-31 and miR-20a levels in the tissue might be helpful to illuminate the molecular mechanisms underlying CRC carcinogenesis and serve as tumor-associated biomarkers for diagnosis" tissue_expression_ns hsa-mir-20a Colorectal Carcinoma 29633600 "detection on miR-21, miR-135b, miR-31 and miR-20a levels in the tissue might be helpful to illuminate the molecular mechanisms underlying CRC carcinogenesis and serve as tumor-associated biomarkers for diagnosis" tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 29633600 "detection on miR-21, miR-135b, miR-31 and miR-20a levels in the tissue might be helpful to illuminate the molecular mechanisms underlying CRC carcinogenesis and serve as tumor-associated biomarkers for diagnosis" tissue_expression_ns hsa-mir-31 Colorectal Carcinoma 29633600 "detection on miR-21, miR-135b, miR-31 and miR-20a levels in the tissue might be helpful to illuminate the molecular mechanisms underlying CRC carcinogenesis and serve as tumor-associated biomarkers for diagnosis" tissue_expression_ns hsa-mir-1 Ischemia-Reperfusion Injury 29642230 "Most commonly reported miRNAs with differential expression between preconditioned and control groups include miR-1, miR-21 and miR-144" tissue_expression_ns hsa-mir-144 Ischemia-Reperfusion Injury 29642230 "Most commonly reported miRNAs with differential expression between preconditioned and control groups include miR-1, miR-21 and miR-144" tissue_expression_ns hsa-mir-21 Ischemia-Reperfusion Injury 29642230 "Most commonly reported miRNAs with differential expression between preconditioned and control groups include miR-1, miR-21 and miR-144" tissue_expression_ns hsa-mir-371a Germ Cell Tumor 29685967 Germ cell tumour subtypes display differential expression of microRNA371a-3p. tissue_expression_ns hsa-mir-128 Pediatric Ependymoma 29704232 "miR-543, miR-495-3p, miR-299-3p, miR-139-5p and miR-128-3p were identified to have CD44 positively co-regulated potential target oncogenes" tissue_expression_ns hsa-mir-139 Pediatric Ependymoma 29704232 "miR-543, miR-495-3p, miR-299-3p, miR-139-5p and miR-128-3p were identified to have CD44 positively co-regulated potential target oncogenes" tissue_expression_ns hsa-mir-299 Pediatric Ependymoma 29704232 "miR-543, miR-495-3p, miR-299-3p, miR-139-5p and miR-128-3p were identified to have CD44 positively co-regulated potential target oncogenes" tissue_expression_ns hsa-mir-495 Pediatric Ependymoma 29704232 "miR-543, miR-495-3p, miR-299-3p, miR-139-5p and miR-128-3p were identified to have CD44 positively co-regulated potential target oncogenes" tissue_expression_ns hsa-mir-543 Pediatric Ependymoma 29704232 "miR-543, miR-495-3p, miR-299-3p, miR-139-5p and miR-128-3p were identified to have CD44 positively co-regulated potential target oncogenes" tissue_expression_ns hsa-mir-327 Parathyroid Carcinoma 29724878 The aberrantly expressed miR-372 partly impairs sensitivity to apoptosis in parathyroid tumor cells. tissue_expression_ns hsa-mir-429 "Carcinoma, Bladder" 29747777 miR-429 expression in bladder cancer and its correlation with tumor behavior and clinical outcome. tissue_expression_ns hsa-let-7b Thyroid Neoplasms 29762469 "The expression of miRNAs hsa-let-7f-5p, has-let-7b-5p hsa-miR-146b-5p and hsa-miR-146b-3p was modulated heterogeneously" tissue_expression_ns hsa-let-7f Thyroid Neoplasms 29762469 "The expression of miRNAs hsa-let-7f-5p, has-let-7b-5p hsa-miR-146b-5p and hsa-miR-146b-3p was modulated heterogeneously" tissue_expression_ns hsa-mir-146b Thyroid Neoplasms 29762469 "The expression of miRNAs hsa-let-7f-5p, has-let-7b-5p hsa-miR-146b-5p and hsa-miR-146b-3p was modulated heterogeneously" tissue_expression_ns hsa-mir-493 "Carcinoma, Breast, Triple Negative" 29777630 MicroRNA-493 is a prognostic factor in triple-negative breast cancer. tissue_expression_ns hsa-mir-34a Leukemia 29780367 Expression of miR-34a in T-Cells Infected by Human T-Lymphotropic Virus 1. tissue_expression_ns hsa-mir-355 Hearing Disorders 29781875 "Most fluids showed expression of miR-355, miR-509p, miR-515p, miR-3p, miR-873, and miR-616, but also showed significant differences between the fluid types, suggesting that miRNA profiling may be used as a diagnostic tool" tissue_expression_ns hsa-mir-509 Hearing Disorders 29781875 "Most fluids showed expression of miR-355, miR-509p, miR-515p, miR-3p, miR-873, and miR-616, but also showed significant differences between the fluid types, suggesting that miRNA profiling may be used as a diagnostic tool" tissue_expression_ns hsa-mir-515 Hearing Disorders 29781875 "Most fluids showed expression of miR-355, miR-509p, miR-515p, miR-3p, miR-873, and miR-616, but also showed significant differences between the fluid types, suggesting that miRNA profiling may be used as a diagnostic tool" tissue_expression_ns hsa-mir-616 Hearing Disorders 29781875 "Most fluids showed expression of miR-355, miR-509p, miR-515p, miR-3p, miR-873, and miR-616, but also showed significant differences between the fluid types, suggesting that miRNA profiling may be used as a diagnostic tool" tissue_expression_ns hsa-mir-873 Hearing Disorders 29781875 "Most fluids showed expression of miR-355, miR-509p, miR-515p, miR-3p, miR-873, and miR-616, but also showed significant differences between the fluid types, suggesting that miRNA profiling may be used as a diagnostic tool" tissue_expression_ns hsa-mir-153 "Carcinoma, Cervical" 29805649 Aberrant expression of miR-153 is associated with the poor prognosis of cervical cancer. tissue_expression_ns hsa-mir-223 "Carcinoma, Breast" 29805680 Exosome-encapsulated microRNA-223-3p as a minimally invasive biomarker for the early detection of invasive breast cancer. tissue_expression_ns hsa-let-7c Colon Neoplasms 29844680 "five hub miRNAs were identified to be related to prognosis (hsa-miR-125b-5p, hsa-miR-145-5p, hsa-let-7c-5p, hsa-miR-218-5p and hsa-miR-125b-2-3p)" tissue_expression_ns hsa-mir-125b Colon Neoplasms 29844680 "five hub miRNAs were identified to be related to prognosis (hsa-miR-125b-5p, hsa-miR-145-5p, hsa-let-7c-5p, hsa-miR-218-5p and hsa-miR-125b-2-3p)" tissue_expression_ns hsa-mir-145 Colon Neoplasms 29844680 "five hub miRNAs were identified to be related to prognosis (hsa-miR-125b-5p, hsa-miR-145-5p, hsa-let-7c-5p, hsa-miR-218-5p and hsa-miR-125b-2-3p)" tissue_expression_ns hsa-mir-218 Colon Neoplasms 29844680 "five hub miRNAs were identified to be related to prognosis (hsa-miR-125b-5p, hsa-miR-145-5p, hsa-let-7c-5p, hsa-miR-218-5p and hsa-miR-125b-2-3p)" tissue_expression_ns hsa-mir-10b Gastric Neoplasms 29848733 "Tumor Expression of miR-10b, miR-21, miR-143 and miR-145 Is Related to Clinicopathological Features of Gastric Cancer in a Central European Population." tissue_expression_ns hsa-mir-143 Gastric Neoplasms 29848733 "Tumor Expression of miR-10b, miR-21, miR-143 and miR-145 Is Related to Clinicopathological Features of Gastric Cancer in a Central European Population." tissue_expression_ns hsa-mir-145 Gastric Neoplasms 29848733 "Tumor Expression of miR-10b, miR-21, miR-143 and miR-145 Is Related to Clinicopathological Features of Gastric Cancer in a Central European Population." tissue_expression_ns hsa-mir-21 Gastric Neoplasms 29848733 "Tumor Expression of miR-10b, miR-21, miR-143 and miR-145 Is Related to Clinicopathological Features of Gastric Cancer in a Central European Population." tissue_expression_ns hsa-let-7a "Carcinoma, Lung, Non-Small-Cell" 29862540 We found that miR-21 and let-7a were significantly dysregulated in NSCLC patients tissue_expression_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 29862540 We found that miR-21 and let-7a were significantly dysregulated in NSCLC patients tissue_expression_ns hsa-mir-185 Gastric Neoplasms 29879180 "The Zsummary algorithm identified an activated module (miR-486, miR-451, miR-185, and miR-600) which might serve as diagnostic biomarker of GC" tissue_expression_ns hsa-mir-451 Gastric Neoplasms 29879180 "The Zsummary algorithm identified an activated module (miR-486, miR-451, miR-185, and miR-600) which might serve as diagnostic biomarker of GC" tissue_expression_ns hsa-mir-486 Gastric Neoplasms 29879180 "The Zsummary algorithm identified an activated module (miR-486, miR-451, miR-185, and miR-600) which might serve as diagnostic biomarker of GC" tissue_expression_ns hsa-mir-600 Gastric Neoplasms 29879180 "The Zsummary algorithm identified an activated module (miR-486, miR-451, miR-185, and miR-600) which might serve as diagnostic biomarker of GC" tissue_expression_ns hsa-mir-146a Hepatoblastoma 29889802 "MicroRNA-17, MicroRNA-19b, MicroRNA-146a, MicroRNA-302d Expressions in Hepatoblastoma and Clinical Importance." tissue_expression_ns hsa-mir-17 Hepatoblastoma 29889802 "MicroRNA-17, MicroRNA-19b, MicroRNA-146a, MicroRNA-302d Expressions in Hepatoblastoma and Clinical Importance." tissue_expression_ns hsa-mir-19b Hepatoblastoma 29889802 "MicroRNA-17, MicroRNA-19b, MicroRNA-146a, MicroRNA-302d Expressions in Hepatoblastoma and Clinical Importance." tissue_expression_ns hsa-mir-302d Hepatoblastoma 29889802 "MicroRNA-17, MicroRNA-19b, MicroRNA-146a, MicroRNA-302d Expressions in Hepatoblastoma and Clinical Importance." tissue_expression_ns hsa-mir-106b "Carcinoma, Hepatocellular" 29899182 "In further analysis, eight miRNAs, including miR-4270, miR-125b-5p, miR-199a-3p, miR-10a-5p, miR-424-5p, miR-195-5p, miR-106b-5p and miR-3651, were retained" tissue_expression_ns hsa-mir-10a "Carcinoma, Hepatocellular" 29899182 "In further analysis, eight miRNAs, including miR-4270, miR-125b-5p, miR-199a-3p, miR-10a-5p, miR-424-5p, miR-195-5p, miR-106b-5p and miR-3651, were retained" tissue_expression_ns hsa-mir-125b "Carcinoma, Hepatocellular" 29899182 "In further analysis, eight miRNAs, including miR-4270, miR-125b-5p, miR-199a-3p, miR-10a-5p, miR-424-5p, miR-195-5p, miR-106b-5p and miR-3651, were retained" tissue_expression_ns hsa-mir-195 "Carcinoma, Hepatocellular" 29899182 "In further analysis, eight miRNAs, including miR-4270, miR-125b-5p, miR-199a-3p, miR-10a-5p, miR-424-5p, miR-195-5p, miR-106b-5p and miR-3651, were retained" tissue_expression_ns hsa-mir-199a "Carcinoma, Hepatocellular" 29899182 "In further analysis, eight miRNAs, including miR-4270, miR-125b-5p, miR-199a-3p, miR-10a-5p, miR-424-5p, miR-195-5p, miR-106b-5p and miR-3651, were retained" tissue_expression_ns hsa-mir-3651 "Carcinoma, Hepatocellular" 29899182 "In further analysis, eight miRNAs, including miR-4270, miR-125b-5p, miR-199a-3p, miR-10a-5p, miR-424-5p, miR-195-5p, miR-106b-5p and miR-3651, were retained" tissue_expression_ns hsa-mir-424 "Carcinoma, Hepatocellular" 29899182 "In further analysis, eight miRNAs, including miR-4270, miR-125b-5p, miR-199a-3p, miR-10a-5p, miR-424-5p, miR-195-5p, miR-106b-5p and miR-3651, were retained" tissue_expression_ns hsa-mir-4270 "Carcinoma, Hepatocellular" 29899182 "In further analysis, eight miRNAs, including miR-4270, miR-125b-5p, miR-199a-3p, miR-10a-5p, miR-424-5p, miR-195-5p, miR-106b-5p and miR-3651, were retained" tissue_expression_ns hsa-mir-155 "Squamous Cell Carcinoma, Tongue" 29909906 "MicroRNA-155, -185 and -193b as biomarkers in human papillomavirus positive and negative tonsillar and base of tongue squamous cell carcinoma." tissue_expression_ns hsa-mir-185 "Squamous Cell Carcinoma, Tongue" 29909906 "MicroRNA-155, -185 and -193b as biomarkers in human papillomavirus positive and negative tonsillar and base of tongue squamous cell carcinoma." tissue_expression_ns hsa-mir-193b "Squamous Cell Carcinoma, Tongue" 29909906 "MicroRNA-155, -185 and -193b as biomarkers in human papillomavirus positive and negative tonsillar and base of tongue squamous cell carcinoma." tissue_expression_ns hsa-mir-146 "Squamous Cell Carcinoma, Oral" 29914173 altered expression of miR-146a and miR-191 was also observed in regenerative areas after OSCC resection tissue_expression_ns hsa-mir-191 "Squamous Cell Carcinoma, Oral" 29914173 altered expression of miR-146a and miR-191 was also observed in regenerative areas after OSCC resection tissue_expression_ns hsa-mir-1252 "Squamous Cell Carcinoma, Head and Neck" 29927717 "The differential expression profiles of these reporter biomolecules were cross-validated by independent RNA-Seq and miRNA-Seq datasets, and risk discrimination performance of the reporter biomolecules, BLNK, CCL2, E4F1, FOSL1, ISG15, MMP9, MYCN, MYH11, miR-1252, miR-29b, miR-29c, miR-3610, miR-431, and miR-523, was also evaluated" tissue_expression_ns hsa-mir-29b "Squamous Cell Carcinoma, Head and Neck" 29927717 "The differential expression profiles of these reporter biomolecules were cross-validated by independent RNA-Seq and miRNA-Seq datasets, and risk discrimination performance of the reporter biomolecules, BLNK, CCL2, E4F1, FOSL1, ISG15, MMP9, MYCN, MYH11, miR-1252, miR-29b, miR-29c, miR-3610, miR-431, and miR-523, was also evaluated" tissue_expression_ns hsa-mir-29c "Squamous Cell Carcinoma, Head and Neck" 29927717 "The differential expression profiles of these reporter biomolecules were cross-validated by independent RNA-Seq and miRNA-Seq datasets, and risk discrimination performance of the reporter biomolecules, BLNK, CCL2, E4F1, FOSL1, ISG15, MMP9, MYCN, MYH11, miR-1252, miR-29b, miR-29c, miR-3610, miR-431, and miR-523, was also evaluated" tissue_expression_ns hsa-mir-3610 "Squamous Cell Carcinoma, Head and Neck" 29927717 "The differential expression profiles of these reporter biomolecules were cross-validated by independent RNA-Seq and miRNA-Seq datasets, and risk discrimination performance of the reporter biomolecules, BLNK, CCL2, E4F1, FOSL1, ISG15, MMP9, MYCN, MYH11, miR-1252, miR-29b, miR-29c, miR-3610, miR-431, and miR-523, was also evaluated" tissue_expression_ns hsa-mir-431 "Squamous Cell Carcinoma, Head and Neck" 29927717 "The differential expression profiles of these reporter biomolecules were cross-validated by independent RNA-Seq and miRNA-Seq datasets, and risk discrimination performance of the reporter biomolecules, BLNK, CCL2, E4F1, FOSL1, ISG15, MMP9, MYCN, MYH11, miR-1252, miR-29b, miR-29c, miR-3610, miR-431, and miR-523, was also evaluated" tissue_expression_ns hsa-mir-523 "Squamous Cell Carcinoma, Head and Neck" 29927717 "The differential expression profiles of these reporter biomolecules were cross-validated by independent RNA-Seq and miRNA-Seq datasets, and risk discrimination performance of the reporter biomolecules, BLNK, CCL2, E4F1, FOSL1, ISG15, MMP9, MYCN, MYH11, miR-1252, miR-29b, miR-29c, miR-3610, miR-431, and miR-523, was also evaluated" tissue_expression_ns hsa-mir-133a Colon Neoplasms 29930763 Extensive screening of microRNA populations identifies hsa-miR-375 and hsa-miR-133a-3p as selective markers for human rectal and colon cancer. tissue_expression_ns hsa-mir-133a Rectal Neoplasms 29930763 Extensive screening of microRNA populations identifies hsa-miR-375 and hsa-miR-133a-3p as selective markers for human rectal and colon cancer. tissue_expression_ns hsa-mir-375 Colon Neoplasms 29930763 Extensive screening of microRNA populations identifies hsa-miR-375 and hsa-miR-133a-3p as selective markers for human rectal and colon cancer. tissue_expression_ns hsa-mir-375 Rectal Neoplasms 29930763 Extensive screening of microRNA populations identifies hsa-miR-375 and hsa-miR-133a-3p as selective markers for human rectal and colon cancer. tissue_expression_ns hsa-mir-221 Liver Fibrosis 29932949 miRNA-221 and miRNA-222 are promising biomarkers for progression of liver fibrosis in HCV Egyptian patients. tissue_expression_ns hsa-mir-222 Liver Fibrosis 29932949 miRNA-221 and miRNA-222 are promising biomarkers for progression of liver fibrosis in HCV Egyptian patients. tissue_expression_ns hsa-mir-21 Glioma 29949235 MicroRNAs as potential biomarkers for the diagnosis of c: A systematic review and meta-analysis. tissue_expression_ns hsa-mir-548c Rectal Neoplasms 29956755 "Among these differentially expressed miRNAs, miR?548c?5p, miR?548d?5p and miR?663a were significantly associated with a CR to nCRT" tissue_expression_ns hsa-mir-548d Rectal Neoplasms 29956755 "Among these differentially expressed miRNAs, miR?548c?5p, miR?548d?5p and miR?663a were significantly associated with a CR to nCRT" tissue_expression_ns hsa-mir-663a Rectal Neoplasms 29956755 "Among these differentially expressed miRNAs, miR?548c?5p, miR?548d?5p and miR?663a were significantly associated with a CR to nCRT" tissue_expression_ns hsa-mir-299 "Carcinoma, Hepatocellular" 29963149 Prognostic value of hsa-mir-299 and hsa-mir-7706 in hepatocellular carcinoma. tissue_expression_ns hsa-mir-7706 "Carcinoma, Hepatocellular" 29963149 Prognostic value of hsa-mir-299 and hsa-mir-7706 in hepatocellular carcinoma. tissue_expression_ns hsa-mir-145 "Squamous Cell Carcinoma, Esophageal" 29963194 "3 types of miRNA (miR-21, miR-25 and miR-145) in serum could serve as potential biomarkers for ESCC" tissue_expression_ns hsa-mir-21 "Squamous Cell Carcinoma, Esophageal" 29963194 "3 types of miRNA (miR-21, miR-25 and miR-145) in serum could serve as potential biomarkers for ESCC" tissue_expression_ns hsa-mir-25 "Squamous Cell Carcinoma, Esophageal" 29963194 "3 types of miRNA (miR-21, miR-25 and miR-145) in serum could serve as potential biomarkers for ESCC" tissue_expression_ns hsa-mir-4758 Ganglioglioma 29963264 MicroRNA519d and microRNA4758 can identify gangliogliomas from dysembryoplastic neuroepithelial tumours and astrocytomas. tissue_expression_ns hsa-mir-519d Ganglioglioma 29963264 MicroRNA519d and microRNA4758 can identify gangliogliomas from dysembryoplastic neuroepithelial tumours and astrocytomas. tissue_expression_ns hsa-mir-122 Liver Injury 29963269 Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury. tissue_expression_ns hsa-mir-34a Amyotrophic Lateral Sclerosis 29973608 "miR-34a and miR504 appeared particularly relevant due to their involvement in the p53 pathway, synaptic vesicle regulation and general involvement in neurodegenerative diseases" tissue_expression_ns hsa-mir-504 Amyotrophic Lateral Sclerosis 29973608 "miR-34a and miR504 appeared particularly relevant due to their involvement in the p53 pathway, synaptic vesicle regulation and general involvement in neurodegenerative diseases" tissue_expression_ns hsa-mir-135b Oral Neoplasms 29976158 "Differential expression of hsa-miR-221, hsa-miR-21, hsa-miR-135b, and hsa-miR-29c suggests a field effect in oral cancer." tissue_expression_ns hsa-mir-21 Oral Neoplasms 29976158 "Differential expression of hsa-miR-221, hsa-miR-21, hsa-miR-135b, and hsa-miR-29c suggests a field effect in oral cancer." tissue_expression_ns hsa-mir-221 Oral Neoplasms 29976158 "Differential expression of hsa-miR-221, hsa-miR-21, hsa-miR-135b, and hsa-miR-29c suggests a field effect in oral cancer." tissue_expression_ns hsa-mir-29c Oral Neoplasms 29976158 "Differential expression of hsa-miR-221, hsa-miR-21, hsa-miR-135b, and hsa-miR-29c suggests a field effect in oral cancer." tissue_expression_ns hsa-mir-15a Lung Neoplasms 29980036 "Hsa-miR-197-3p, hsa-miR-29a-3p, hsa-miR-15a-5p, hsa-miR-16-5p and hsa-miR-92a-3p are found significantly expressed in association with exposures" tissue_expression_ns hsa-mir-16 Lung Neoplasms 29980036 "Hsa-miR-197-3p, hsa-miR-29a-3p, hsa-miR-15a-5p, hsa-miR-16-5p and hsa-miR-92a-3p are found significantly expressed in association with exposures" tissue_expression_ns hsa-mir-197 Lung Neoplasms 29980036 "Hsa-miR-197-3p, hsa-miR-29a-3p, hsa-miR-15a-5p, hsa-miR-16-5p and hsa-miR-92a-3p are found significantly expressed in association with exposures" tissue_expression_ns hsa-mir-29a Lung Neoplasms 29980036 "Hsa-miR-197-3p, hsa-miR-29a-3p, hsa-miR-15a-5p, hsa-miR-16-5p and hsa-miR-92a-3p are found significantly expressed in association with exposures" tissue_expression_ns hsa-mir-92a Lung Neoplasms 29980036 "Hsa-miR-197-3p, hsa-miR-29a-3p, hsa-miR-15a-5p, hsa-miR-16-5p and hsa-miR-92a-3p are found significantly expressed in association with exposures" tissue_expression_ns hsa-mir-320 Chronic Obstructive Pulmonary Disease 29981854 Genome-wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer Development. tissue_expression_ns hsa-mir-483 Adrenal Cortex Neoplasms 29982598 The lack of significantly different expression of hsa-miR-483-3p and hsa-miR-483-5p between AML and ACC might limit their applicability as diagnostic miRNA markers for ACC tissue_expression_ns hsa-let-7a "Carcinoma, Breast" 29995098 Expression of tumor suppressors miR-195 and let-7a as potential biomarkers of invasive breast cancer. tissue_expression_ns hsa-mir-195 "Carcinoma, Breast" 29995098 Expression of tumor suppressors miR-195 and let-7a as potential biomarkers of invasive breast cancer. tissue_expression_ns hsa-mir-99a Prostate Neoplasms 29997385 Expression of microRNA-99a-3p in Prostate Cancer Based on Bioinformatics Data and Meta-Analysis of a Literature Review of 965 Cases. tissue_expression_ns hsa-mir-141 "Carcinoma, Renal Cell" 30008851 miR-224/miR-141 ratio as a novel diagnostic biomarker in renal cell carcinoma. tissue_expression_ns hsa-mir-224 "Carcinoma, Renal Cell" 30008851 miR-224/miR-141 ratio as a novel diagnostic biomarker in renal cell carcinoma. tissue_expression_ns hsa-mir-141 Prostate Neoplasms 30014459 "Combination of three miRNA (miR-141, miR-21, and miR-375) as potential diagnostic tool for prostate cancer recognition." tissue_expression_ns hsa-mir-21 Prostate Neoplasms 30014459 "Combination of three miRNA (miR-141, miR-21, and miR-375) as potential diagnostic tool for prostate cancer recognition." tissue_expression_ns hsa-mir-375 Prostate Neoplasms 30014459 "Combination of three miRNA (miR-141, miR-21, and miR-375) as potential diagnostic tool for prostate cancer recognition." tissue_expression_ns hsa-mir-18a Colorectal Carcinoma 30018727 miR-18a-5p functioned as an oncogene and prognostic biomarker in RCC tissue_expression_ns hsa-let-7a "Carcinoma, Breast" 30019863 Differential altered expression of let-7a and miR-205 tumor-suppressor miRNAs in different subtypes of breast cancer under treatment with Taxol. tissue_expression_ns hsa-mir-205 "Carcinoma, Breast" 30019863 Differential altered expression of let-7a and miR-205 tumor-suppressor miRNAs in different subtypes of breast cancer under treatment with Taxol. tissue_expression_ns hsa-mir-200b "Adenocarcinoma, Lung" 30022565 Altered editing level of microRNAs is a potential biomarker in lung adenocarcinoma. tissue_expression_ns hsa-mir-99a "Adenocarcinoma, Lung" 30022565 Altered editing level of microRNAs is a potential biomarker in lung adenocarcinoma. tissue_expression_ns hsa-mir-33 Coronary Artery Disease 30022694 Circulating miRNA-33: a potential biomarker in patients with Coronary Artery Disease (CAD). tissue_expression_ns hsa-mir-221 Osteosarcoma 30024497 MiRNA-221 from tissue may predict the prognosis of patients with osteosarcoma. tissue_expression_ns hsa-mir-184 Glaucoma 30025119 "Relative expression patterns of hsa-miR-184, hsa-miR-486-5p, and hsa-miR-93-5p were confirmed by quantitative PCR" tissue_expression_ns hsa-mir-486 Glaucoma 30025119 "Relative expression patterns of hsa-miR-184, hsa-miR-486-5p, and hsa-miR-93-5p were confirmed by quantitative PCR" tissue_expression_ns hsa-mir-93 Glaucoma 30025119 "Relative expression patterns of hsa-miR-184, hsa-miR-486-5p, and hsa-miR-93-5p were confirmed by quantitative PCR" tissue_expression_ns hsa-let-7g "Carcinoma, Hepatocellular" 30026054 "A number of miRNAs implicated in HCC, including miR-101, miR-140, miR-152, miR-199a-3p, and let-7g, were downregulated in CHB" tissue_expression_ns hsa-mir-101 "Carcinoma, Hepatocellular" 30026054 "A number of miRNAs implicated in HCC, including miR-101, miR-140, miR-152, miR-199a-3p, and let-7g, were downregulated in CHB" tissue_expression_ns hsa-mir-140 "Carcinoma, Hepatocellular" 30026054 "A number of miRNAs implicated in HCC, including miR-101, miR-140, miR-152, miR-199a-3p, and let-7g, were downregulated in CHB" tissue_expression_ns hsa-mir-152 "Carcinoma, Hepatocellular" 30026054 "A number of miRNAs implicated in HCC, including miR-101, miR-140, miR-152, miR-199a-3p, and let-7g, were downregulated in CHB" tissue_expression_ns hsa-mir-199a "Carcinoma, Hepatocellular" 30026054 "A number of miRNAs implicated in HCC, including miR-101, miR-140, miR-152, miR-199a-3p, and let-7g, were downregulated in CHB" tissue_expression_ns hsa-mir-100 "Carcinoma, Urothelial" 30026881 "six were associated with high risk (hsa-miR-99a-5p, hsa-miR-100-5p, hsa-miR-125b-5p, hsa-miR-4324, hsa-miR-34b-5p, and hsa-miR-135a-3p) and three were shown to be protective (hsa-miR-145-5p, hsa-miR-29c-3p, and hsa-miR-33b-3p)" tissue_expression_ns hsa-mir-125b "Carcinoma, Urothelial" 30026881 "six were associated with high risk (hsa-miR-99a-5p, hsa-miR-100-5p, hsa-miR-125b-5p, hsa-miR-4324, hsa-miR-34b-5p, and hsa-miR-135a-3p) and three were shown to be protective (hsa-miR-145-5p, hsa-miR-29c-3p, and hsa-miR-33b-3p)" tissue_expression_ns hsa-mir-135a "Carcinoma, Urothelial" 30026881 "six were associated with high risk (hsa-miR-99a-5p, hsa-miR-100-5p, hsa-miR-125b-5p, hsa-miR-4324, hsa-miR-34b-5p, and hsa-miR-135a-3p) and three were shown to be protective (hsa-miR-145-5p, hsa-miR-29c-3p, and hsa-miR-33b-3p)" tissue_expression_ns hsa-mir-145 "Carcinoma, Urothelial" 30026881 "six were associated with high risk (hsa-miR-99a-5p, hsa-miR-100-5p, hsa-miR-125b-5p, hsa-miR-4324, hsa-miR-34b-5p, and hsa-miR-135a-3p) and three were shown to be protective (hsa-miR-145-5p, hsa-miR-29c-3p, and hsa-miR-33b-3p)" tissue_expression_ns hsa-mir-29c "Carcinoma, Urothelial" 30026881 "six were associated with high risk (hsa-miR-99a-5p, hsa-miR-100-5p, hsa-miR-125b-5p, hsa-miR-4324, hsa-miR-34b-5p, and hsa-miR-135a-3p) and three were shown to be protective (hsa-miR-145-5p, hsa-miR-29c-3p, and hsa-miR-33b-3p)" tissue_expression_ns hsa-mir-33b "Carcinoma, Urothelial" 30026881 "six were associated with high risk (hsa-miR-99a-5p, hsa-miR-100-5p, hsa-miR-125b-5p, hsa-miR-4324, hsa-miR-34b-5p, and hsa-miR-135a-3p) and three were shown to be protective (hsa-miR-145-5p, hsa-miR-29c-3p, and hsa-miR-33b-3p)" tissue_expression_ns hsa-mir-34b "Carcinoma, Urothelial" 30026881 "six were associated with high risk (hsa-miR-99a-5p, hsa-miR-100-5p, hsa-miR-125b-5p, hsa-miR-4324, hsa-miR-34b-5p, and hsa-miR-135a-3p) and three were shown to be protective (hsa-miR-145-5p, hsa-miR-29c-3p, and hsa-miR-33b-3p)" tissue_expression_ns hsa-mir-4324 "Carcinoma, Urothelial" 30026881 "six were associated with high risk (hsa-miR-99a-5p, hsa-miR-100-5p, hsa-miR-125b-5p, hsa-miR-4324, hsa-miR-34b-5p, and hsa-miR-135a-3p) and three were shown to be protective (hsa-miR-145-5p, hsa-miR-29c-3p, and hsa-miR-33b-3p)" tissue_expression_ns hsa-mir-99a "Carcinoma, Urothelial" 30026881 "six were associated with high risk (hsa-miR-99a-5p, hsa-miR-100-5p, hsa-miR-125b-5p, hsa-miR-4324, hsa-miR-34b-5p, and hsa-miR-135a-3p) and three were shown to be protective (hsa-miR-145-5p, hsa-miR-29c-3p, and hsa-miR-33b-3p)" tissue_expression_ns hsa-mir-143 Prostate Neoplasms 30027097 "MicroRNAs like miR-23b, miR-95, miR-143, and miR-183 can be utilized in assisting the diagnosis and prognosis of prostate cancer as biomarkers" tissue_expression_ns hsa-mir-183 Prostate Neoplasms 30027097 "MicroRNAs like miR-23b, miR-95, miR-143, and miR-183 can be utilized in assisting the diagnosis and prognosis of prostate cancer as biomarkers" tissue_expression_ns hsa-mir-23b Prostate Neoplasms 30027097 "MicroRNAs like miR-23b, miR-95, miR-143, and miR-183 can be utilized in assisting the diagnosis and prognosis of prostate cancer as biomarkers" tissue_expression_ns hsa-mir-95 Prostate Neoplasms 30027097 "MicroRNAs like miR-23b, miR-95, miR-143, and miR-183 can be utilized in assisting the diagnosis and prognosis of prostate cancer as biomarkers" tissue_expression_ns hsa-mir-141 Prostate Neoplasms 30037718 "The refined miRNA panel (KCa-6: miR-27b, -942, -497, -144, -141 and -27a) was more capable of predicting the overall survival than was any single miRNAs included in it" tissue_expression_ns hsa-mir-144 Prostate Neoplasms 30037718 "The refined miRNA panel (KCa-6: miR-27b, -942, -497, -144, -141 and -27a) was more capable of predicting the overall survival than was any single miRNAs included in it" tissue_expression_ns hsa-mir-27a Prostate Neoplasms 30037718 "The refined miRNA panel (KCa-6: miR-27b, -942, -497, -144, -141 and -27a) was more capable of predicting the overall survival than was any single miRNAs included in it" tissue_expression_ns hsa-mir-27b Prostate Neoplasms 30037718 "The refined miRNA panel (KCa-6: miR-27b, -942, -497, -144, -141 and -27a) was more capable of predicting the overall survival than was any single miRNAs included in it" tissue_expression_ns hsa-mir-497 Prostate Neoplasms 30037718 "The refined miRNA panel (KCa-6: miR-27b, -942, -497, -144, -141 and -27a) was more capable of predicting the overall survival than was any single miRNAs included in it" tissue_expression_ns hsa-mir-942 Prostate Neoplasms 30037718 "The refined miRNA panel (KCa-6: miR-27b, -942, -497, -144, -141 and -27a) was more capable of predicting the overall survival than was any single miRNAs included in it" tissue_expression_ns hsa-mir-185 Asthma 30040124 Asthma diagnosis using integrated analysis of eosinophil microRNAs. tissue_expression_ns hsa-mir-21 Cholangiocarcinoma 30050323 miR-21 may be a promising biomarker for diagnosis and prognosis of CCA tissue_expression_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 30050938 Multiple miRNAs such as miR-21 and miR-210 could be used as diagnostic tools for NSCLC tissue_expression_ns hsa-mir-210 "Carcinoma, Lung, Non-Small-Cell" 30050938 Multiple miRNAs such as miR-21 and miR-210 could be used as diagnostic tools for NSCLC tissue_expression_ns hsa-mir-139 "Carcinoma, Breast" 30055304 "Tree-based machine learning modelstrained in my analysis used hsa-miR-139 with hsa-miR-183 to classify breast tumors from normal samples, and hsa-miR4728 with hsa-miR190b to further classify these tumors into three major subtypes of breast cancer" tissue_expression_ns hsa-mir-183 "Carcinoma, Breast" 30055304 "Tree-based machine learning modelstrained in my analysis used hsa-miR-139 with hsa-miR-183 to classify breast tumors from normal samples, and hsa-miR4728 with hsa-miR190b to further classify these tumors into three major subtypes of breast cancer" tissue_expression_ns hsa-mir-1296 "Carcinoma, Hepatocellular" 30064138 "four miRNAs (mir-1296, mir-23c, mir-149, and mir-95) were finally selected for further validation and analysis" tissue_expression_ns hsa-mir-149 "Carcinoma, Hepatocellular" 30064138 "four miRNAs (mir-1296, mir-23c, mir-149, and mir-95) were finally selected for further validation and analysis" tissue_expression_ns hsa-mir-23c "Carcinoma, Hepatocellular" 30064138 "four miRNAs (mir-1296, mir-23c, mir-149, and mir-95) were finally selected for further validation and analysis" tissue_expression_ns hsa-mir-95 "Carcinoma, Hepatocellular" 30064138 "four miRNAs (mir-1296, mir-23c, mir-149, and mir-95) were finally selected for further validation and analysis" tissue_expression_ns hsa-mir-99a "Squamous Cell Carcinoma, Head and Neck" 30087832 our study may provide insights into the expression and mechanism of miR-99a-5p in HNSCC tissue_expression_ns hsa-mir-155 "Carcinoma, Breast" 30088260 "metformin may modulate the pro-apoptotic Bax, anti-apoptotic Bcl-2, MMP-2, MMP-9, miR-21 and miR-155 expression levels. These findings may be instrumental for the clinical management and/or (targeted) treatment of breast cancer" tissue_expression_ns hsa-mir-21 "Carcinoma, Breast" 30088260 "metformin may modulate the pro-apoptotic Bax, anti-apoptotic Bcl-2, MMP-2, MMP-9, miR-21 and miR-155 expression levels. These findings may be instrumental for the clinical management and/or (targeted) treatment of breast cancer" tissue_expression_ns hsa-mir-17 Lung Neoplasms 30089594 "six microRNAs (miR-17, miR-190b, miR-19a, miR-19b, miR-26b, and miR-375) provided high diagnostic accuracy in discriminating lung cancer patients from healthy individuals" tissue_expression_ns hsa-mir-190b Lung Neoplasms 30089594 "six microRNAs (miR-17, miR-190b, miR-19a, miR-19b, miR-26b, and miR-375) provided high diagnostic accuracy in discriminating lung cancer patients from healthy individuals" tissue_expression_ns hsa-mir-19a Lung Neoplasms 30089594 "six microRNAs (miR-17, miR-190b, miR-19a, miR-19b, miR-26b, and miR-375) provided high diagnostic accuracy in discriminating lung cancer patients from healthy individuals" tissue_expression_ns hsa-mir-19b Lung Neoplasms 30089594 "six microRNAs (miR-17, miR-190b, miR-19a, miR-19b, miR-26b, and miR-375) provided high diagnostic accuracy in discriminating lung cancer patients from healthy individuals" tissue_expression_ns hsa-mir-26b Lung Neoplasms 30089594 "six microRNAs (miR-17, miR-190b, miR-19a, miR-19b, miR-26b, and miR-375) provided high diagnostic accuracy in discriminating lung cancer patients from healthy individuals" tissue_expression_ns hsa-mir-375 Lung Neoplasms 30089594 "six microRNAs (miR-17, miR-190b, miR-19a, miR-19b, miR-26b, and miR-375) provided high diagnostic accuracy in discriminating lung cancer patients from healthy individuals" tissue_expression_ns hsa-mir-141 Ovarian Neoplasms 30095616 MicroRNA-200 and microRNA-30 family as prognostic molecular signatures in ovarian cancer: A meta-analysis. tissue_expression_ns hsa-mir-200a Ovarian Neoplasms 30095616 MicroRNA-200 and microRNA-30 family as prognostic molecular signatures in ovarian cancer: A meta-analysis. tissue_expression_ns hsa-mir-200b Ovarian Neoplasms 30095616 MicroRNA-200 and microRNA-30 family as prognostic molecular signatures in ovarian cancer: A meta-analysis. tissue_expression_ns hsa-mir-200c Ovarian Neoplasms 30095616 MicroRNA-200 and microRNA-30 family as prognostic molecular signatures in ovarian cancer: A meta-analysis. tissue_expression_ns hsa-mir-30d Ovarian Neoplasms 30095616 MicroRNA-200 and microRNA-30 family as prognostic molecular signatures in ovarian cancer: A meta-analysis. tissue_expression_ns hsa-mir-326 Gastric Neoplasms 30096452 Purified sulforaphane from broccoli (Brassica oleracea var. italica) leads to alterations of CDX1 and CDX2 expression and changes in miR-9 and miR-326 levels in human gastric cancer cells. tissue_expression_ns hsa-mir-9 Gastric Neoplasms 30096452 Purified sulforaphane from broccoli (Brassica oleracea var. italica) leads to alterations of CDX1 and CDX2 expression and changes in miR-9 and miR-326 levels in human gastric cancer cells. tissue_expression_ns hsa-mir-199b Parathyroid Carcinoma 30104706 Differential expression of miRNA199b-5p as a novel biomarker for sporadic and hereditary parathyroid tumors. tissue_expression_ns hsa-mir-183 Renal Oncocytoma 30116406 "miR-498 (formation of the oncocytoma-specific slice-form of vimentin, Vim3), miR-183 (associated with increased CO2 levels), miR-205, and miR-31 (signaling through downregulation of PKC epsilon, shown previously)" tissue_expression_ns hsa-mir-205 Renal Oncocytoma 30116406 "miR-498 (formation of the oncocytoma-specific slice-form of vimentin, Vim3), miR-183 (associated with increased CO2 levels), miR-205, and miR-31 (signaling through downregulation of PKC epsilon, shown previously)" tissue_expression_ns hsa-mir-31 Renal Oncocytoma 30116406 "miR-498 (formation of the oncocytoma-specific slice-form of vimentin, Vim3), miR-183 (associated with increased CO2 levels), miR-205, and miR-31 (signaling through downregulation of PKC epsilon, shown previously)" tissue_expression_ns hsa-mir-498 Renal Oncocytoma 30116406 "miR-498 (formation of the oncocytoma-specific slice-form of vimentin, Vim3), miR-183 (associated with increased CO2 levels), miR-205, and miR-31 (signaling through downregulation of PKC epsilon, shown previously)" tissue_expression_ns hsa-let-7a-3 "Adenocarcinoma, Pancreatic Ductal" 30127641 "Eleven miRNAs (hsa-mir-501, hsa-mir-4521, hsa-mir-5091, hsa-mir-24-1, hsa-mir-126, hsa-mir-30e, hsa-mir-3157, hsa-let-7a-3, hsa-mir-133a-1, hsa-mir-4709, and hsa-mir-421) were used to construct a prognostic signature using the step function" tissue_expression_ns hsa-mir-126 "Adenocarcinoma, Pancreatic Ductal" 30127641 "Eleven miRNAs (hsa-mir-501, hsa-mir-4521, hsa-mir-5091, hsa-mir-24-1, hsa-mir-126, hsa-mir-30e, hsa-mir-3157, hsa-let-7a-3, hsa-mir-133a-1, hsa-mir-4709, and hsa-mir-421) were used to construct a prognostic signature using the step function" tissue_expression_ns hsa-mir-133a-1 "Adenocarcinoma, Pancreatic Ductal" 30127641 "Eleven miRNAs (hsa-mir-501, hsa-mir-4521, hsa-mir-5091, hsa-mir-24-1, hsa-mir-126, hsa-mir-30e, hsa-mir-3157, hsa-let-7a-3, hsa-mir-133a-1, hsa-mir-4709, and hsa-mir-421) were used to construct a prognostic signature using the step function" tissue_expression_ns hsa-mir-24-1 "Adenocarcinoma, Pancreatic Ductal" 30127641 "Eleven miRNAs (hsa-mir-501, hsa-mir-4521, hsa-mir-5091, hsa-mir-24-1, hsa-mir-126, hsa-mir-30e, hsa-mir-3157, hsa-let-7a-3, hsa-mir-133a-1, hsa-mir-4709, and hsa-mir-421) were used to construct a prognostic signature using the step function" tissue_expression_ns hsa-mir-30e "Adenocarcinoma, Pancreatic Ductal" 30127641 "Eleven miRNAs (hsa-mir-501, hsa-mir-4521, hsa-mir-5091, hsa-mir-24-1, hsa-mir-126, hsa-mir-30e, hsa-mir-3157, hsa-let-7a-3, hsa-mir-133a-1, hsa-mir-4709, and hsa-mir-421) were used to construct a prognostic signature using the step function" tissue_expression_ns hsa-mir-3157 "Adenocarcinoma, Pancreatic Ductal" 30127641 "Eleven miRNAs (hsa-mir-501, hsa-mir-4521, hsa-mir-5091, hsa-mir-24-1, hsa-mir-126, hsa-mir-30e, hsa-mir-3157, hsa-let-7a-3, hsa-mir-133a-1, hsa-mir-4709, and hsa-mir-421) were used to construct a prognostic signature using the step function" tissue_expression_ns hsa-mir-421 "Adenocarcinoma, Pancreatic Ductal" 30127641 "Eleven miRNAs (hsa-mir-501, hsa-mir-4521, hsa-mir-5091, hsa-mir-24-1, hsa-mir-126, hsa-mir-30e, hsa-mir-3157, hsa-let-7a-3, hsa-mir-133a-1, hsa-mir-4709, and hsa-mir-421) were used to construct a prognostic signature using the step function" tissue_expression_ns hsa-mir-4521 "Adenocarcinoma, Pancreatic Ductal" 30127641 "Eleven miRNAs (hsa-mir-501, hsa-mir-4521, hsa-mir-5091, hsa-mir-24-1, hsa-mir-126, hsa-mir-30e, hsa-mir-3157, hsa-let-7a-3, hsa-mir-133a-1, hsa-mir-4709, and hsa-mir-421) were used to construct a prognostic signature using the step function" tissue_expression_ns hsa-mir-4709 "Adenocarcinoma, Pancreatic Ductal" 30127641 "Eleven miRNAs (hsa-mir-501, hsa-mir-4521, hsa-mir-5091, hsa-mir-24-1, hsa-mir-126, hsa-mir-30e, hsa-mir-3157, hsa-let-7a-3, hsa-mir-133a-1, hsa-mir-4709, and hsa-mir-421) were used to construct a prognostic signature using the step function" tissue_expression_ns hsa-mir-501 "Adenocarcinoma, Pancreatic Ductal" 30127641 "Eleven miRNAs (hsa-mir-501, hsa-mir-4521, hsa-mir-5091, hsa-mir-24-1, hsa-mir-126, hsa-mir-30e, hsa-mir-3157, hsa-let-7a-3, hsa-mir-133a-1, hsa-mir-4709, and hsa-mir-421) were used to construct a prognostic signature using the step function" tissue_expression_ns hsa-mir-5091 "Adenocarcinoma, Pancreatic Ductal" 30127641 "Eleven miRNAs (hsa-mir-501, hsa-mir-4521, hsa-mir-5091, hsa-mir-24-1, hsa-mir-126, hsa-mir-30e, hsa-mir-3157, hsa-let-7a-3, hsa-mir-133a-1, hsa-mir-4709, and hsa-mir-421) were used to construct a prognostic signature using the step function" tissue_expression_ns hsa-mir-203 Esophageal Neoplasms 30127973 Identification and verification of differentially expressed microRNAs and their target genes for the diagnosis of esophageal cancer. tissue_expression_ns hsa-let-7b Smoke Inhalation Injury 30139538 Expression profile of microRNAs in bronchoalveolar lavage fluid of rats as predictors for smoke inhalation injury. tissue_expression_ns hsa-let-7c Smoke Inhalation Injury 30139538 Expression profile of microRNAs in bronchoalveolar lavage fluid of rats as predictors for smoke inhalation injury. tissue_expression_ns hsa-mir-205 Smoke Inhalation Injury 30139538 Expression profile of microRNAs in bronchoalveolar lavage fluid of rats as predictors for smoke inhalation injury. tissue_expression_ns hsa-mir-34b Smoke Inhalation Injury 30139538 Expression profile of microRNAs in bronchoalveolar lavage fluid of rats as predictors for smoke inhalation injury. tissue_expression_ns hsa-mir-34c Smoke Inhalation Injury 30139538 Expression profile of microRNAs in bronchoalveolar lavage fluid of rats as predictors for smoke inhalation injury. tissue_expression_ns hsa-mir-92a Smoke Inhalation Injury 30139538 Expression profile of microRNAs in bronchoalveolar lavage fluid of rats as predictors for smoke inhalation injury. tissue_expression_ns hsa-mir-92b Smoke Inhalation Injury 30139538 Expression profile of microRNAs in bronchoalveolar lavage fluid of rats as predictors for smoke inhalation injury. tissue_expression_ns hsa-mir-1 Tetralogy Of Fallot 30150777 "miR-1/miR-133, which have been identified as essential for cardiac development, account for the most variance of sRNA expression between sexes in TOF hearts" tissue_expression_ns hsa-mir-133b Tetralogy Of Fallot 30150777 "miR-1/miR-133, which have been identified as essential for cardiac development, account for the most variance of sRNA expression between sexes in TOF hearts" tissue_expression_ns hsa-mir-125a "Carcinoma, Pancreatic" 30165365 "We identified that miR-23a, miR-30a, miR-125a, miR-129-1, miR-181b-1, miR-203, miR-221, miR-222, and miR-1301 had moderate diagnostic value for PaCa and predicted overall survival in PaCa patients" tissue_expression_ns hsa-mir-129-1 "Carcinoma, Pancreatic" 30165365 "We identified that miR-23a, miR-30a, miR-125a, miR-129-1, miR-181b-1, miR-203, miR-221, miR-222, and miR-1301 had moderate diagnostic value for PaCa and predicted overall survival in PaCa patients" tissue_expression_ns hsa-mir-1301 "Carcinoma, Pancreatic" 30165365 "We identified that miR-23a, miR-30a, miR-125a, miR-129-1, miR-181b-1, miR-203, miR-221, miR-222, and miR-1301 had moderate diagnostic value for PaCa and predicted overall survival in PaCa patients" tissue_expression_ns hsa-mir-181b-1 "Carcinoma, Pancreatic" 30165365 "We identified that miR-23a, miR-30a, miR-125a, miR-129-1, miR-181b-1, miR-203, miR-221, miR-222, and miR-1301 had moderate diagnostic value for PaCa and predicted overall survival in PaCa patients" tissue_expression_ns hsa-mir-203 "Carcinoma, Pancreatic" 30165365 "We identified that miR-23a, miR-30a, miR-125a, miR-129-1, miR-181b-1, miR-203, miR-221, miR-222, and miR-1301 had moderate diagnostic value for PaCa and predicted overall survival in PaCa patients" tissue_expression_ns hsa-mir-221 "Carcinoma, Pancreatic" 30165365 "We identified that miR-23a, miR-30a, miR-125a, miR-129-1, miR-181b-1, miR-203, miR-221, miR-222, and miR-1301 had moderate diagnostic value for PaCa and predicted overall survival in PaCa patients" tissue_expression_ns hsa-mir-222 "Carcinoma, Pancreatic" 30165365 "We identified that miR-23a, miR-30a, miR-125a, miR-129-1, miR-181b-1, miR-203, miR-221, miR-222, and miR-1301 had moderate diagnostic value for PaCa and predicted overall survival in PaCa patients" tissue_expression_ns hsa-mir-23a "Carcinoma, Pancreatic" 30165365 "We identified that miR-23a, miR-30a, miR-125a, miR-129-1, miR-181b-1, miR-203, miR-221, miR-222, and miR-1301 had moderate diagnostic value for PaCa and predicted overall survival in PaCa patients" tissue_expression_ns hsa-mir-30a "Carcinoma, Pancreatic" 30165365 "We identified that miR-23a, miR-30a, miR-125a, miR-129-1, miR-181b-1, miR-203, miR-221, miR-222, and miR-1301 had moderate diagnostic value for PaCa and predicted overall survival in PaCa patients" tissue_expression_ns hsa-mir-181a Myeloma 30170425 The expression and role of miR-181a in multiple myeloma. tissue_expression_ns hsa-let-7g "Carcinoma, Head And Neck" 30171046 "A five-miRNA-signature (hsa-let-7g-3p, hsa-miR-6508-5p, hsa-miR-210-5p, hsa-miR-4306 and hsa-miR-7161-3p) predicted freedom from recurrence in DKTK-ROG, which was confirmed in LMU-KKG" tissue_expression_ns hsa-mir-210 "Carcinoma, Head And Neck" 30171046 "A five-miRNA-signature (hsa-let-7g-3p, hsa-miR-6508-5p, hsa-miR-210-5p, hsa-miR-4306 and hsa-miR-7161-3p) predicted freedom from recurrence in DKTK-ROG, which was confirmed in LMU-KKG" tissue_expression_ns hsa-mir-4306 "Carcinoma, Head And Neck" 30171046 "A five-miRNA-signature (hsa-let-7g-3p, hsa-miR-6508-5p, hsa-miR-210-5p, hsa-miR-4306 and hsa-miR-7161-3p) predicted freedom from recurrence in DKTK-ROG, which was confirmed in LMU-KKG" tissue_expression_ns hsa-mir-6508 "Carcinoma, Head And Neck" 30171046 "A five-miRNA-signature (hsa-let-7g-3p, hsa-miR-6508-5p, hsa-miR-210-5p, hsa-miR-4306 and hsa-miR-7161-3p) predicted freedom from recurrence in DKTK-ROG, which was confirmed in LMU-KKG" tissue_expression_ns hsa-mir-7161 "Carcinoma, Head And Neck" 30171046 "A five-miRNA-signature (hsa-let-7g-3p, hsa-miR-6508-5p, hsa-miR-210-5p, hsa-miR-4306 and hsa-miR-7161-3p) predicted freedom from recurrence in DKTK-ROG, which was confirmed in LMU-KKG" tissue_expression_ns hsa-mir-140 Multiple Sclerosis 30175165 "5 miRNAs (hsa-miR-484, hsa-miR-140-5p, hsa-miR-320a, hsa-miR-486-5p, and hsa-miR-320c) showed a significant difference between patients with MS and healthy individuals" tissue_expression_ns hsa-mir-320a Multiple Sclerosis 30175165 "5 miRNAs (hsa-miR-484, hsa-miR-140-5p, hsa-miR-320a, hsa-miR-486-5p, and hsa-miR-320c) showed a significant difference between patients with MS and healthy individuals" tissue_expression_ns hsa-mir-320c Multiple Sclerosis 30175165 "5 miRNAs (hsa-miR-484, hsa-miR-140-5p, hsa-miR-320a, hsa-miR-486-5p, and hsa-miR-320c) showed a significant difference between patients with MS and healthy individuals" tissue_expression_ns hsa-mir-484 Multiple Sclerosis 30175165 "5 miRNAs (hsa-miR-484, hsa-miR-140-5p, hsa-miR-320a, hsa-miR-486-5p, and hsa-miR-320c) showed a significant difference between patients with MS and healthy individuals" tissue_expression_ns hsa-mir-486 Multiple Sclerosis 30175165 "5 miRNAs (hsa-miR-484, hsa-miR-140-5p, hsa-miR-320a, hsa-miR-486-5p, and hsa-miR-320c) showed a significant difference between patients with MS and healthy individuals" tissue_expression_ns hsa-mir-4511 "Carcinoma, Bladder" 30183088 "the proposed non-invasive diagnostic tool based on the expression ratio of urinary cell-free miR-6124 to miR-4511 can reduce unnecessary cystoscopies in patients with hematuria undergoing evaluation for BC, with a minimal loss in sensitivity for detecting cancer" tissue_expression_ns hsa-mir-6124 "Carcinoma, Bladder" 30183088 "the proposed non-invasive diagnostic tool based on the expression ratio of urinary cell-free miR-6124 to miR-4511 can reduce unnecessary cystoscopies in patients with hematuria undergoing evaluation for BC, with a minimal loss in sensitivity for detecting cancer" tissue_expression_ns hsa-mir-18a Neoplasms [unspecific] 30189225 Ribonucleic-acid-biomarker candidates for early-phase group detection of common cancers. tissue_expression_ns hsa-mir-21 Neoplasms [unspecific] 30189225 Ribonucleic-acid-biomarker candidates for early-phase group detection of common cancers. tissue_expression_ns hsa-mir-221 Neoplasms [unspecific] 30189225 Ribonucleic-acid-biomarker candidates for early-phase group detection of common cancers. tissue_expression_ns hsa-mir-375 Neoplasms [unspecific] 30189225 Ribonucleic-acid-biomarker candidates for early-phase group detection of common cancers. tissue_expression_ns hsa-mir-1290 "Carcinoma, Lung, Non-Small-Cell" 30190521 "combination of miR-1290, miR-196b and miR-135a in tumor tissue, and miR-21, miR-25, miR27b, and miR-326 in plasma were predictive for response to platinum-based chemotherapy in advanced NSCLC" tissue_expression_ns hsa-mir-135a "Carcinoma, Lung, Non-Small-Cell" 30190521 "combination of miR-1290, miR-196b and miR-135a in tumor tissue, and miR-21, miR-25, miR27b, and miR-326 in plasma were predictive for response to platinum-based chemotherapy in advanced NSCLC" tissue_expression_ns hsa-mir-196b "Carcinoma, Lung, Non-Small-Cell" 30190521 "combination of miR-1290, miR-196b and miR-135a in tumor tissue, and miR-21, miR-25, miR27b, and miR-326 in plasma were predictive for response to platinum-based chemotherapy in advanced NSCLC" tissue_expression_ns hsa-mir-10a "Carcinoma, Cervical" 30191988 "The upregulation of some circulating miRNAs, for example, miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue-specific miRNAs, for example, miR-7, miR-10a, miR-17-5p, miR-135b, miR-149, and miR-203 have been found in patients with CC" tissue_expression_ns hsa-mir-135b "Carcinoma, Cervical" 30191988 "The upregulation of some circulating miRNAs, for example, miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue-specific miRNAs, for example, miR-7, miR-10a, miR-17-5p, miR-135b, miR-149, and miR-203 have been found in patients with CC" tissue_expression_ns hsa-mir-149 "Carcinoma, Cervical" 30191988 "The upregulation of some circulating miRNAs, for example, miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue-specific miRNAs, for example, miR-7, miR-10a, miR-17-5p, miR-135b, miR-149, and miR-203 have been found in patients with CC" tissue_expression_ns hsa-mir-17 "Carcinoma, Cervical" 30191988 "The upregulation of some circulating miRNAs, for example, miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue-specific miRNAs, for example, miR-7, miR-10a, miR-17-5p, miR-135b, miR-149, and miR-203 have been found in patients with CC" tissue_expression_ns hsa-mir-203 "Carcinoma, Cervical" 30191988 "The upregulation of some circulating miRNAs, for example, miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue-specific miRNAs, for example, miR-7, miR-10a, miR-17-5p, miR-135b, miR-149, and miR-203 have been found in patients with CC" tissue_expression_ns hsa-mir-7 "Carcinoma, Cervical" 30191988 "The upregulation of some circulating miRNAs, for example, miRNA-20a, miRNA-203, miRNA-21, miRNA-205, miRNA-218, and miR-485-5, as well as tissue-specific miRNAs, for example, miR-7, miR-10a, miR-17-5p, miR-135b, miR-149, and miR-203 have been found in patients with CC" tissue_expression_ns hsa-mir-141 "Carcinoma, Bladder" 30194772 "miR-21-5p, miR-141-3p, and miR-205-5p levels in urine-promising biomarkers for the identification of prostate and bladder cancer." tissue_expression_ns hsa-mir-141 Prostate Neoplasms 30194772 "miR-21-5p, miR-141-3p, and miR-205-5p levels in urine-promising biomarkers for the identification of prostate and bladder cancer." tissue_expression_ns hsa-mir-205 "Carcinoma, Bladder" 30194772 "miR-21-5p, miR-141-3p, and miR-205-5p levels in urine-promising biomarkers for the identification of prostate and bladder cancer." tissue_expression_ns hsa-mir-205 Prostate Neoplasms 30194772 "miR-21-5p, miR-141-3p, and miR-205-5p levels in urine-promising biomarkers for the identification of prostate and bladder cancer." tissue_expression_ns hsa-mir-21 "Carcinoma, Bladder" 30194772 "miR-21-5p, miR-141-3p, and miR-205-5p levels in urine-promising biomarkers for the identification of prostate and bladder cancer." tissue_expression_ns hsa-mir-21 Prostate Neoplasms 30194772 "miR-21-5p, miR-141-3p, and miR-205-5p levels in urine-promising biomarkers for the identification of prostate and bladder cancer." tissue_expression_ns hsa-mir-301a Prostate Neoplasms 30195463 miR-301a expression: Diagnostic and prognostic marker for prostate cancer. tissue_expression_ns hsa-mir-200b Glioma 30197535 MicroRNA-200b expression level is negatively associated with pathological grading in human gliomas. tissue_expression_ns hsa-mir-206 "Colitis, Ulcerative" 30204869 miR-206 as a Biomarker for Response to Mesalamine Treatment in Ulcerative Colitis. tissue_expression_ns hsa-mir-1246 Gastrointestinal Neoplasms 30235938 Exosomal miR-1246 in body fluids is a potential biomarker for gastrointestinal cancer. tissue_expression_ns hsa-mir-320a Cardiac Myxoma 30250535 Specific miRNA expression profile in the blood serum of cardiac myxoma patients. tissue_expression_ns hsa-mir-634 Cardiac Myxoma 30250535 Specific miRNA expression profile in the blood serum of cardiac myxoma patients. tissue_expression_ns hsa-mir-1260a Prostate Neoplasms 30250996 Expression patterns and bioinformatic analysis of miR-1260a and miR-1274a in Prostate Cancer Tunisian patients. tissue_expression_ns hsa-mir-1274a Prostate Neoplasms 30250996 Expression patterns and bioinformatic analysis of miR-1260a and miR-1274a in Prostate Cancer Tunisian patients. tissue_expression_ns hsa-mir-125b "Carcinoma, Lung, Non-Small-Cell" 30254489 Establishment and validation of a 7-microRNA prognostic signature for non-small cell lung cancer. tissue_expression_ns hsa-mir-148b "Carcinoma, Lung, Non-Small-Cell" 30254489 Establishment and validation of a 7-microRNA prognostic signature for non-small cell lung cancer. tissue_expression_ns hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 30254489 Establishment and validation of a 7-microRNA prognostic signature for non-small cell lung cancer. tissue_expression_ns hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 30254489 Establishment and validation of a 7-microRNA prognostic signature for non-small cell lung cancer. tissue_expression_ns hsa-mir-32 "Carcinoma, Lung, Non-Small-Cell" 30254489 Establishment and validation of a 7-microRNA prognostic signature for non-small cell lung cancer. tissue_expression_ns hsa-mir-365 "Carcinoma, Lung, Non-Small-Cell" 30254489 Establishment and validation of a 7-microRNA prognostic signature for non-small cell lung cancer. tissue_expression_ns hsa-mir-375 "Carcinoma, Lung, Non-Small-Cell" 30254489 Establishment and validation of a 7-microRNA prognostic signature for non-small cell lung cancer. tissue_expression_ns hsa-mir-196a Pancreatic Adenocarcinoma 30258849 Evaluation of Plasma MicroRNAs as Diagnostic and Prognostic Biomarkers in Pancreatic Adenocarcinoma: miR-196a and miR-210 Could Be Negative and Positive Prognostic Markers tissue_expression_ns hsa-mir-210 Pancreatic Adenocarcinoma 30258849 Evaluation of Plasma MicroRNAs as Diagnostic and Prognostic Biomarkers in Pancreatic Adenocarcinoma: miR-196a and miR-210 Could Be Negative and Positive Prognostic Markers tissue_expression_ns hsa-mir-21 Stroke 30267810 MiR-21 was found to be normally up and down regulated in all types of strokes tissue_expression_ns hsa-mir-138 "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-145 "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-153 "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-182 "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-183 "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-214 "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-214 "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-29b "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-29c "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-30b "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-30c "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-33a "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-34a "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-34a "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-34c "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-34c "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-93 "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-96 "Adenocarcinoma, Lung" 30271594 Expression profiling and microRNA regulation of the LKB1 pathway in young and aged lung adenocarcinoma patients. tissue_expression_ns hsa-mir-17 Gastrointestinal Neoplasms 30275704 Prognostic value of miR-17-5p in gastrointestinal cancers: a systematic review and meta-analysis. tissue_expression_ns hsa-mir-139 "Carcinoma, Hepatocellular" 30290990 Low microRNA-139 expression associates with poor prognosis in patients with tumors: A meta-analysis. tissue_expression_ns hsa-mir-106b Pancreatic Endocrine Carcinoma 30299890 "The expression of hsa-miR-106b, hsa-miR-10a and especially hsa-miR-21 has prognostic relevance regarding progression-free and overall survival in patients with PanNENs" tissue_expression_ns hsa-mir-10a Pancreatic Endocrine Carcinoma 30299890 "The expression of hsa-miR-106b, hsa-miR-10a and especially hsa-miR-21 has prognostic relevance regarding progression-free and overall survival in patients with PanNENs" tissue_expression_ns hsa-mir-21 Pancreatic Endocrine Carcinoma 30299890 "The expression of hsa-miR-106b, hsa-miR-10a and especially hsa-miR-21 has prognostic relevance regarding progression-free and overall survival in patients with PanNENs" tissue_expression_ns hsa-mir-182 "Carcinoma, Bladder" 30304549 Comprehensive analysis of microRNA-messenger RNA regulatory network in gemcitabine-resistant bladder cancer cells. tissue_expression_ns hsa-mir-320a "Carcinoma, Bladder" 30304549 Comprehensive analysis of microRNA-messenger RNA regulatory network in gemcitabine-resistant bladder cancer cells. tissue_expression_ns hsa-mir-550a "Carcinoma, Bladder" 30304549 Comprehensive analysis of microRNA-messenger RNA regulatory network in gemcitabine-resistant bladder cancer cells. tissue_expression_ns hsa-mir-10a "Carcinoma, Urothelial, Upper Tract" 30315887 "OS was best predicted by miR-10a-5p, miR-199a-5p, miR-30c-5p, and miR-10b-5p" tissue_expression_ns hsa-mir-10b "Carcinoma, Urothelial, Upper Tract" 30315887 "OS was best predicted by miR-10a-5p, miR-199a-5p, miR-30c-5p, and miR-10b-5p" tissue_expression_ns hsa-mir-199a "Carcinoma, Urothelial, Upper Tract" 30315887 "OS was best predicted by miR-10a-5p, miR-199a-5p, miR-30c-5p, and miR-10b-5p" tissue_expression_ns hsa-mir-30c "Carcinoma, Urothelial, Upper Tract" 30315887 "OS was best predicted by miR-10a-5p, miR-199a-5p, miR-30c-5p, and miR-10b-5p" tissue_expression_ns hsa-let-7c "Carcinoma, Bladder" 30322728 " we identified a subset of 6 miRs (let-7c, miR-135a, miR-135b, miR-148a, miR-204, miR-345) that distinguished BC from controls with an area under the curve of 88.3%" tissue_expression_ns hsa-mir-135a "Carcinoma, Bladder" 30322728 " we identified a subset of 6 miRs (let-7c, miR-135a, miR-135b, miR-148a, miR-204, miR-345) that distinguished BC from controls with an area under the curve of 88.3%" tissue_expression_ns hsa-mir-135b "Carcinoma, Bladder" 30322728 " we identified a subset of 6 miRs (let-7c, miR-135a, miR-135b, miR-148a, miR-204, miR-345) that distinguished BC from controls with an area under the curve of 88.3%" tissue_expression_ns hsa-mir-148a "Carcinoma, Bladder" 30322728 " we identified a subset of 6 miRs (let-7c, miR-135a, miR-135b, miR-148a, miR-204, miR-345) that distinguished BC from controls with an area under the curve of 88.3%" tissue_expression_ns hsa-mir-204 "Carcinoma, Bladder" 30322728 " we identified a subset of 6 miRs (let-7c, miR-135a, miR-135b, miR-148a, miR-204, miR-345) that distinguished BC from controls with an area under the curve of 88.3%" tissue_expression_ns hsa-mir-345 "Carcinoma, Bladder" 30322728 " we identified a subset of 6 miRs (let-7c, miR-135a, miR-135b, miR-148a, miR-204, miR-345) that distinguished BC from controls with an area under the curve of 88.3%" tissue_expression_ns hsa-mir-141 Prostate Neoplasms 30334974 "PCA3, hK2, and miRNA-141 were biomarkers of Pca with potential clinical application value, especially in patients with PSA gray area" tissue_expression_ns hsa-mir-296 "Squamous Cell Carcinoma, Lung" 30337605 "miR-296-5p, miR-324-3p, and miR-3928-3p expression was significantly associated with poor prognosis" tissue_expression_ns hsa-mir-324 "Squamous Cell Carcinoma, Lung" 30337605 "miR-296-5p, miR-324-3p, and miR-3928-3p expression was significantly associated with poor prognosis" tissue_expression_ns hsa-mir-3928 "Squamous Cell Carcinoma, Lung" 30337605 "miR-296-5p, miR-324-3p, and miR-3928-3p expression was significantly associated with poor prognosis" tissue_expression_ns hsa-mir-424 Prostate Neoplasms 30345533 differential expression of miR-424 and miR-572 in recurrent PCa specimens can serve as novel biomarkers for prediction of Pca progression tissue_expression_ns hsa-mir-572 Prostate Neoplasms 30345533 differential expression of miR-424 and miR-572 in recurrent PCa specimens can serve as novel biomarkers for prediction of Pca progression tissue_expression_ns hsa-mir-106a "Cardiomyopathy, Dilated" 30346833 miR-15b-5p and miR-106a-5p expression levels could potentially serve as useful biomarkers for distinguishing between IsDC and IdDC tissue_expression_ns hsa-mir-15b "Cardiomyopathy, Dilated" 30346833 miR-15b-5p and miR-106a-5p expression levels could potentially serve as useful biomarkers for distinguishing between IsDC and IdDC tissue_expression_ns hsa-mir-155 Colorectal Carcinoma 30348685 "Expression of Circulating miR-155, miR-21, miR-221, miR-30a, miR-34a and miR-29a: Comparison of Colonic and Rectal Cancer." tissue_expression_ns hsa-mir-21 Colorectal Carcinoma 30348685 "Expression of Circulating miR-155, miR-21, miR-221, miR-30a, miR-34a and miR-29a: Comparison of Colonic and Rectal Cancer." tissue_expression_ns hsa-mir-221 Colorectal Carcinoma 30348685 "Expression of Circulating miR-155, miR-21, miR-221, miR-30a, miR-34a and miR-29a: Comparison of Colonic and Rectal Cancer." tissue_expression_ns hsa-mir-29a Colorectal Carcinoma 30348685 "Expression of Circulating miR-155, miR-21, miR-221, miR-30a, miR-34a and miR-29a: Comparison of Colonic and Rectal Cancer." tissue_expression_ns hsa-mir-30a Colorectal Carcinoma 30348685 "Expression of Circulating miR-155, miR-21, miR-221, miR-30a, miR-34a and miR-29a: Comparison of Colonic and Rectal Cancer." tissue_expression_ns hsa-mir-34a Colorectal Carcinoma 30348685 "Expression of Circulating miR-155, miR-21, miR-221, miR-30a, miR-34a and miR-29a: Comparison of Colonic and Rectal Cancer." tissue_expression_ns hsa-mir-1246 "Carcinoma, Breast" 30350935 In Situ Detection of Plasma Exosomal MicroRNA-1246 for Breast Cancer Diagnostics by a Au Nanoflare Probe. tissue_expression_ns hsa-mir-4507 Prader-Willi Syndrome 30352401 "A different signature of miRNAs significantly distinguished PWS with steatosis from PWS without steatosis, involving miR-619-5p, miR-4507, miR-4656, miR-7847-3p and miR-6782-5p" tissue_expression_ns hsa-mir-4656 Prader-Willi Syndrome 30352401 "A different signature of miRNAs significantly distinguished PWS with steatosis from PWS without steatosis, involving miR-619-5p, miR-4507, miR-4656, miR-7847-3p and miR-6782-5p" tissue_expression_ns hsa-mir-619 Prader-Willi Syndrome 30352401 "A different signature of miRNAs significantly distinguished PWS with steatosis from PWS without steatosis, involving miR-619-5p, miR-4507, miR-4656, miR-7847-3p and miR-6782-5p" tissue_expression_ns hsa-mir-6782 Prader-Willi Syndrome 30352401 "A different signature of miRNAs significantly distinguished PWS with steatosis from PWS without steatosis, involving miR-619-5p, miR-4507, miR-4656, miR-7847-3p and miR-6782-5p" tissue_expression_ns hsa-mir-7847 Prader-Willi Syndrome 30352401 "A different signature of miRNAs significantly distinguished PWS with steatosis from PWS without steatosis, involving miR-619-5p, miR-4507, miR-4656, miR-7847-3p and miR-6782-5p" tissue_expression_ns hsa-mir-1283 Endometriosis 30359864 "the treatment of quercetin induced miR-503-5p, miR-1283, miR-3714 and miR-6867-5p related to CCND1 in both cell lines and also stimulated miR-503-5p and miR-546 expression in the mouse model" tissue_expression_ns hsa-mir-3714 Endometriosis 30359864 "the treatment of quercetin induced miR-503-5p, miR-1283, miR-3714 and miR-6867-5p related to CCND1 in both cell lines and also stimulated miR-503-5p and miR-546 expression in the mouse model" tissue_expression_ns hsa-mir-503 Endometriosis 30359864 "the treatment of quercetin induced miR-503-5p, miR-1283, miR-3714 and miR-6867-5p related to CCND1 in both cell lines and also stimulated miR-503-5p and miR-546 expression in the mouse model" tissue_expression_ns hsa-mir-503 Endometriosis 30359864 "the treatment of quercetin induced miR-503-5p, miR-1283, miR-3714 and miR-6867-5p related to CCND1 in both cell lines and also stimulated miR-503-5p and miR-546 expression in the mouse model" tissue_expression_ns hsa-mir-6867 Endometriosis 30359864 "the treatment of quercetin induced miR-503-5p, miR-1283, miR-3714 and miR-6867-5p related to CCND1 in both cell lines and also stimulated miR-503-5p and miR-546 expression in the mouse model" tissue_expression_ns hsa-mir-21 X-linked Alport Syndrome 30370838 Abnormal Expression of miR-21 in Kidney Tissue of Dogs With X-Linked Hereditary Nephropathy: A Canine Model of Chronic Kidney Disease. tissue_expression_ns hsa-mir-1307 "Carcinoma, Breast" 30382159 "four miRNAs, hsa-miR-503, hsa-miR-1307, hsa-miR-212 and hsa-miR-592, were significantly associated with the prognosis of patients with breast cancer" tissue_expression_ns hsa-mir-212 "Carcinoma, Breast" 30382159 "four miRNAs, hsa-miR-503, hsa-miR-1307, hsa-miR-212 and hsa-miR-592, were significantly associated with the prognosis of patients with breast cancer" tissue_expression_ns hsa-mir-503 "Carcinoma, Breast" 30382159 "four miRNAs, hsa-miR-503, hsa-miR-1307, hsa-miR-212 and hsa-miR-592, were significantly associated with the prognosis of patients with breast cancer" tissue_expression_ns hsa-mir-592 "Carcinoma, Breast" 30382159 "four miRNAs, hsa-miR-503, hsa-miR-1307, hsa-miR-212 and hsa-miR-592, were significantly associated with the prognosis of patients with breast cancer" tissue_expression_up hsa-mir-155 "Lymphoma, Hodgkin" 12661002 upregulated tissue_expression_up hsa-mir-17 "Leukemia, B-Cell" 15944707 overexpression tissue_expression_up hsa-mir-17 "Lymphoma, B-Cell" 15944707 overexpressed tissue_expression_up hsa-mir-18a "Leukemia, B-Cell" 15944707 overexpression tissue_expression_up hsa-mir-18a "Lymphoma, B-Cell" 15944707 overexpressed tissue_expression_up hsa-mir-19a "Leukemia, B-Cell" 15944707 overexpression tissue_expression_up hsa-mir-19a "Lymphoma, B-Cell" 15944707 overexpressed tissue_expression_up hsa-mir-19b-1 "Leukemia, B-Cell" 15944707 overexpression tissue_expression_up hsa-mir-19b-1 "Lymphoma, B-Cell" 15944707 overexpressed tissue_expression_up hsa-mir-19b-2 "Lymphoma, B-Cell" 15944707 overexpressed tissue_expression_up hsa-mir-20a "Leukemia, B-Cell" 15944707 overexpression tissue_expression_up hsa-mir-92a-1 "Leukemia, B-Cell" 15944707 overexpression tissue_expression_up hsa-mir-21 Glioblastoma 16024602 upregulated tissue_expression_up hsa-mir-21 Glioblastoma 16039986 upregulated tissue_expression_up hsa-mir-155 "Lymphoma, Large B-Cell, Diffuse" 16041695 upregulated tissue_expression_up hsa-mir-155 Breast Neoplasms 16103053 upregulated tissue_expression_up hsa-mir-21 Breast Neoplasms 16103053 upregulation tissue_expression_up hsa-mir-15b Hepatitis C Virus Infection 16331254 overexpression tissue_expression_up hsa-mir-182 Hepatitis C Virus Infection 16331254 overexpression tissue_expression_up hsa-mir-18a "Carcinoma, Hepatocellular" 16331254 upregulated tissue_expression_up hsa-mir-18b "Carcinoma, Hepatocellular" 16331254 upregulated tissue_expression_up hsa-mir-199b Hepatitis C Virus Infection 16331254 overexpression tissue_expression_up hsa-mir-20a "Carcinoma, Hepatocellular" 16331254 overexpression tissue_expression_up hsa-mir-20b "Carcinoma, Hepatocellular" 16331254 overexpression tissue_expression_up hsa-mir-224 "Carcinoma, Hepatocellular" 16331254 upregulated tissue_expression_up hsa-mir-224 Hepatitis C Virus Infection 16331254 overexpression tissue_expression_up hsa-mir-92a-1 "Carcinoma, Hepatocellular" 16331254 overexpression tissue_expression_up hsa-mir-92a-2 "Carcinoma, Hepatocellular" 16331254 overexpression tissue_expression_up hsa-mir-92b "Carcinoma, Hepatocellular" 16331254 overexpression tissue_expression_up hsa-mir-221 "Carcinoma, Thyroid, Papillary" 16365291 upregulation tissue_expression_up hsa-mir-106a Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-106a Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-106a Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-107 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-107 Gastric Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-107 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-128-2 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-128-2 Lung Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-128-2 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-146a Breast Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-146a Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-146a Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-146b Breast Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-146b Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-146b Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-155 Breast Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-155 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-155 Lung Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-17 Breast Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-17 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-17 Lung Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-17 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-17 Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-181b-1 Breast Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-181b-1 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-181b-1 Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-191 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-191 Gastric Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-191 Lung Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-191 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-191 Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-199a-1 Lung Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-199a-1 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-199a-1 Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-20a Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-20a Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-20a Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-21 Breast Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-21 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-21 Gastric Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-21 Lung Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-21 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-21 Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-214 Gastric Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-214 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-214 Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-221 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-221 Gastric Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-221 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-223 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-223 Gastric Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-223 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-223 Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-24-1 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-24-1 Gastric Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-24-1 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-24-2 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-24-2 Gastric Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-24-2 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-25 Gastric Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-25 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-25 Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-29b-1 Breast Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-29b-1 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-29b-1 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-29b-1 Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-30c-1 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-30c-1 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-30c-1 Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-30c-2 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-30c-2 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-30c-2 Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-32 Colon Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-32 Pancreatic Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-32 Prostate Neoplasms 16461460 overexpressed tissue_expression_up hsa-mir-106a Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-146a Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-146b Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-150 Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-155 Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-17 Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-191 Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-197 Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-203 Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-205 Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-21 Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-210 Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-212 Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-214 Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-24-2 Lung Neoplasms 16530703 upregulation tissue_expression_up hsa-mir-221 "Carcinoma, Thyroid, Papillary" 16728577 upregulation tissue_expression_up hsa-mir-222 "Carcinoma, Thyroid, Papillary" 16728577 upregulation tissue_expression_up hsa-mir-141 Cholangiocarcinoma 16762633 "MiR-21, miR-141, and miR-200b were highly over-expressed in malignant cholangiocytes." tissue_expression_up hsa-mir-200b Cholangiocarcinoma 16762633 "MiR-21, miR-141, and miR-200b were highly over-expressed in malignant cholangiocytes." tissue_expression_up hsa-mir-21 Cholangiocarcinoma 16762633 "MiR-21, miR-141, and miR-200b were highly over-expressed in malignant cholangiocytes." tissue_expression_up hsa-mir-183 Lung Neoplasms 17028596 "mir-124, mir-183, mir-223, mir-29 mir-124a-3 downregulated in lung cancer (Yanaihara et al., 2006);" tissue_expression_up hsa-mir-206 Breast Neoplasms 17028596 "mir-206 upregulated in breast cancer (Iorio et al., 2005)." tissue_expression_up hsa-mir-21 Neoplasms [unspecific] 17028596 "mir-21 upregulated in glioblastoma and associated with antiapoptosis upregulated in breast cancer (Iorio et al., 2005), and in a signature for solid cancers (Volinia et al., 2006)." tissue_expression_up hsa-mir-221 Thyroid Neoplasms 17028596 Upregulated mir-221/222 in papillary thyroid cancer tissue_expression_up hsa-mir-222 Thyroid Neoplasms 17028596 Upregulated mir-221/222 in papillary thyroid cancer tissue_expression_up hsa-mir-9-1 Breast Neoplasms 17028596 "mir-9 increased in breast cancers (Iorio et al., 2005), but downregulated in lung cancers (Yanaihara et al., 2006)" tissue_expression_up hsa-mir-9-2 Breast Neoplasms 17028596 "mir-9 increased in breast cancers (Iorio et al., 2005), but downregulated in lung cancers (Yanaihara et al., 2006)" tissue_expression_up hsa-mir-9-3 Breast Neoplasms 17028596 "mir-9 increased in breast cancers (Iorio et al., 2005), but downregulated in lung cancers (Yanaihara et al., 2006)" tissue_expression_up hsa-mir-195 "Cardiomyopathy, Hypertrophic" 17108080 "miR-23a, miR-23b, miR-24, miR-195, and miR-214, all of which were up-regulated during cardiac hypertrophy, appeared to be capable of inducing hypertrophic growth in vitro." tissue_expression_up hsa-mir-195 Heart Failure 17108080 overexpressed tissue_expression_up hsa-mir-199a-1 "Cardiomyopathy, Hypertrophic" 17108080 overexpressed tissue_expression_up hsa-mir-199a-2 "Cardiomyopathy, Hypertrophic" 17108080 overexpressed tissue_expression_up hsa-mir-214 "Cardiomyopathy, Hypertrophic" 17108080 overexpressed tissue_expression_up hsa-mir-23a "Cardiomyopathy, Hypertrophic" 17108080 "miR-23a, miR-23b, miR-24, miR-195, and miR-214, all of which were up-regulated during cardiac hypertrophy, appeared to be capable of inducing hypertrophic growth in vitro." tissue_expression_up hsa-mir-23b "Cardiomyopathy, Hypertrophic" 17108080 "miR-23a, miR-23b, miR-24, miR-195, and miR-214, all of which were up-regulated during cardiac hypertrophy, appeared to be capable of inducing hypertrophic growth in vitro." tissue_expression_up hsa-mir-24-1 "Cardiomyopathy, Hypertrophic" 17108080 "miR-23a, miR-23b, miR-24, miR-195, and miR-214, all of which were up-regulated during cardiac hypertrophy, appeared to be capable of inducing hypertrophic growth in vitro." tissue_expression_up hsa-mir-24-2 "Cardiomyopathy, Hypertrophic" 17108080 "miR-23a, miR-23b, miR-24, miR-195, and miR-214, all of which were up-regulated during cardiac hypertrophy, appeared to be capable of inducing hypertrophic growth in vitro." tissue_expression_up hsa-mir-106b Schizophrenia 17326821 upregulation tissue_expression_up hsa-mir-1-1 Coronary Artery Disease 17401374 overexpressed tissue_expression_up hsa-mir-1-2 Coronary Artery Disease 17401374 overexpressed tissue_expression_up hsa-mir-196a-2 Pancreatic Neoplasms 17473300 "Finally, high expression of miR-196a-2 was found to predict poor survival (median, 14.3 months [95% confidence interval, 12.4-16.2] vs 26.5 months [95% confidence interval, 23.4-29.6]; P = .009)." tissue_expression_up hsa-mir-21 Breast Neoplasms 17531469 "MiR-21 is found to be highly expressed in numerous cancers like breast cancer, and glioblastoma and pancreatic cancer." tissue_expression_up hsa-mir-21 Cholangiocarcinoma 17531469 "Recently Meng et al. showed that miR-21 is also overexpressed in malignant cholangiocarcinomas, a highly chemoresistant cancer type, knockdown of miR-21 sensitised cholangiocarcinoma cell lines for treatment with gemcitabin, whereas transfection of non-malignant cholangiocytes with precursor miR-21 made cells more resistant to gemcitabin." tissue_expression_up hsa-mir-21 Glioblastoma 17531469 "MiR-21 is found to be highly expressed in numerous cancers like breast cancer, and glioblastoma and pancreatic cancer." tissue_expression_up hsa-mir-21 Pancreatic Neoplasms 17531469 "MiR-21 is found to be highly expressed in numerous cancers like breast cancer, and glioblastoma and pancreatic cancer." tissue_expression_up hsa-mir-143 "Carcinoma, Rectal" 17553685 Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells. tissue_expression_up hsa-mir-126 "Leukemia-Lymphoma, Precursor B-Cell Lymphoblastic" 17604727 strongly expressed tissue_expression_up hsa-let-7a-1 Heart Failure 17606841 upregulated tissue_expression_up hsa-let-7a-2 Heart Failure 17606841 upregulated tissue_expression_up hsa-let-7b Heart Failure 17606841 upregulated tissue_expression_up hsa-let-7c Heart Failure 17606841 upregulated tissue_expression_up hsa-let-7d Heart Failure 17606841 upregulated tissue_expression_up hsa-let-7e Heart Failure 17606841 upregulated tissue_expression_up hsa-let-7f-1 Heart Failure 17606841 upregulated tissue_expression_up hsa-let-7f-2 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-106b Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-10b Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-1-1 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-1-2 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-125a Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-126 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-129-2 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-130a Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-132 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-196a-1 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-196a-2 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-199b Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-200c Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-204 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-205 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-208a Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-21 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-210 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-211 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-212 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-215 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-26a-1 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-26a-2 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-28 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-296 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-297 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-29a Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-29b-1 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-300 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-302a Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-32 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-320a Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-330 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-340 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-34b Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-365a Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-365b Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-367 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-372 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-373 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-377 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-381 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-382 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-423 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-424 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-429 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-432 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-500a Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-520c Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-525 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-98 Heart Failure 17606841 upregulated tissue_expression_up hsa-mir-146a Psoriasis 17622355 miR-146a was significantly over-expressed in psoriatic lesional skin p<0.001) but not in atopic eczema lesions when compared with healthy skin. tissue_expression_up hsa-mir-203 Psoriasis 17622355 upregulation (lead to downregulation of its target SOCS3) tissue_expression_up hsa-mir-21 Atopic Dermatitis 17622355 miR-21 was significantly up-regulated both psoriasis (p<0.001) and atopic eczema (p<0.001) as compared with healthy skin. tissue_expression_up hsa-mir-21 Psoriasis 17622355 miR-21 was significantly up-regulated both psoriasis (p<0.001) and atopic eczema (p<0.001) as compared with healthy skin. tissue_expression_up hsa-mir-221 Glioblastoma 17627278 "Interestingly, high levels of miR-221&222 appear in glioblastomas and correlate with low levels of p27(Kip1) protein. Thus, deregulated expression of miR-221&222 promotes cancerous growth by inhibiting the expression of p27(Kip1)." tissue_expression_up hsa-mir-222 Glioblastoma 17627278 "Interestingly, high levels of miR-221&222 appear in glioblastomas and correlate with low levels of p27(Kip1) protein. Thus, deregulated expression of miR-221&222 promotes cancerous growth by inhibiting the expression of p27(Kip1)." tissue_expression_up hsa-mir-103-1 Bladder Neoplasms 17826655 "Human micro-RNAs miR-223, miR-26b, miR-221, miR-103-1, miR-185, miR-23b, miR-203, miR-17-5p, miR-23a, and miR-205 were significantly up-regulated in bladder cancers (P < 0.05) compared to normal bladder mucosa." tissue_expression_up hsa-mir-17 Bladder Neoplasms 17826655 "Human micro-RNAs miR-223, miR-26b, miR-221, miR-103-1, miR-185, miR-23b, miR-203, miR-17-5p, miR-23a, and miR-205 were significantly up-regulated in bladder cancers (P < 0.05) compared to normal bladder mucosa." tissue_expression_up hsa-mir-185 Bladder Neoplasms 17826655 "Human micro-RNAs miR-223, miR-26b, miR-221, miR-103-1, miR-185, miR-23b, miR-203, miR-17-5p, miR-23a, and miR-205 were significantly up-regulated in bladder cancers (P < 0.05) compared to normal bladder mucosa." tissue_expression_up hsa-mir-203 Bladder Neoplasms 17826655 "Human micro-RNAs miR-223, miR-26b, miR-221, miR-103-1, miR-185, miR-23b, miR-203, miR-17-5p, miR-23a, and miR-205 were significantly up-regulated in bladder cancers (P < 0.05) compared to normal bladder mucosa." tissue_expression_up hsa-mir-205 Bladder Neoplasms 17826655 "Human micro-RNAs miR-223, miR-26b, miR-221, miR-103-1, miR-185, miR-23b, miR-203, miR-17-5p, miR-23a, and miR-205 were significantly up-regulated in bladder cancers (P < 0.05) compared to normal bladder mucosa." tissue_expression_up hsa-mir-221 Bladder Neoplasms 17826655 "Human micro-RNAs miR-223, miR-26b, miR-221, miR-103-1, miR-185, miR-23b, miR-203, miR-17-5p, miR-23a, and miR-205 were significantly up-regulated in bladder cancers (P < 0.05) compared to normal bladder mucosa." tissue_expression_up hsa-mir-223 Bladder Neoplasms 17826655 "Human micro-RNAs miR-223, miR-26b, miR-221, miR-103-1, miR-185, miR-23b, miR-203, miR-17-5p, miR-23a, and miR-205 were significantly up-regulated in bladder cancers (P < 0.05) compared to normal bladder mucosa." tissue_expression_up hsa-mir-23a Bladder Neoplasms 17826655 "Human micro-RNAs miR-223, miR-26b, miR-221, miR-103-1, miR-185, miR-23b, miR-203, miR-17-5p, miR-23a, and miR-205 were significantly up-regulated in bladder cancers (P < 0.05) compared to normal bladder mucosa." tissue_expression_up hsa-mir-23b Bladder Neoplasms 17826655 "Human micro-RNAs miR-223, miR-26b, miR-221, miR-103-1, miR-185, miR-23b, miR-203, miR-17-5p, miR-23a, and miR-205 were significantly up-regulated in bladder cancers (P < 0.05) compared to normal bladder mucosa." tissue_expression_up hsa-mir-26b Bladder Neoplasms 17826655 "Human micro-RNAs miR-223, miR-26b, miR-221, miR-103-1, miR-185, miR-23b, miR-203, miR-17-5p, miR-23a, and miR-205 were significantly up-regulated in bladder cancers (P < 0.05) compared to normal bladder mucosa." tissue_expression_up hsa-mir-140 Ovarian Neoplasms 17875710 "The most significantly overexpressed miRNAs were miR-200a, miR-141, miR-200c, and miR-200b, whereas miR-199a, miR-140, miR-145, and miR-125b1 were among the most down-modulated miRNAs." tissue_expression_up hsa-mir-141 Ovarian Neoplasms 17875710 "The most significantly overexpressed miRNAs were miR-200a, miR-141, miR-200c, and miR-200b, whereas miR-199a, miR-140, miR-145, and miR-125b1 were among the most down-modulated miRNAs." tissue_expression_up hsa-mir-145 Ovarian Neoplasms 17875710 "The most significantly overexpressed miRNAs were miR-200a, miR-141, miR-200c, and miR-200b, whereas miR-199a, miR-140, miR-145, and miR-125b1 were among the most down-modulated miRNAs." tissue_expression_up hsa-mir-199a Ovarian Neoplasms 17875710 "The most significantly overexpressed miRNAs were miR-200a, miR-141, miR-200c, and miR-200b, whereas miR-199a, miR-140, miR-145, and miR-125b1 were among the most down-modulated miRNAs." tissue_expression_up hsa-mir-200a Ovarian Neoplasms 17875710 "The most significantly overexpressed miRNAs were miR-200a, miR-141, miR-200c, and miR-200b, whereas miR-199a, miR-140, miR-145, and miR-125b1 were among the most down-modulated miRNAs." tissue_expression_up hsa-mir-200b Ovarian Neoplasms 17875710 "The most significantly overexpressed miRNAs were miR-200a, miR-141, miR-200c, and miR-200b, whereas miR-199a, miR-140, miR-145, and miR-125b1 were among the most down-modulated miRNAs." tissue_expression_up hsa-mir-200c Ovarian Neoplasms 17875710 "The most significantly overexpressed miRNAs were miR-200a, miR-141, miR-200c, and miR-200b, whereas miR-199a, miR-140, miR-145, and miR-125b1 were among the most down-modulated miRNAs." tissue_expression_up hsa-mir-34a Colon Neoplasms 17875987 highly upregulated tissue_expression_up hsa-mir-34a Neuroblastoma 17888029 All of the Fe-NTA-induced rat renal carcinomas and an array of human cancers (151 positive cases of 177) showed high expression of miRNA-34a. tissue_expression_up hsa-mir-183 Retinitis Pigmentosa 18034880 "Expression of miR-1 and miR-133 decreased by more than 2.5-fold (P < 0.001), whereas expression of miR-96 and miR-183 increased by more than 3-fold (P < 0.001) in Pro347Ser retinas, as validated by qPCR." tissue_expression_up hsa-mir-96 Retinitis Pigmentosa 18034880 "Expression of miR-1 and miR-133 decreased by more than 2.5-fold (P < 0.001), whereas expression of miR-96 and miR-183 increased by more than 3-fold (P < 0.001) in Pro347Ser retinas, as validated by qPCR." tissue_expression_up hsa-let-7g Schizophrenia 18184693 upregulated tissue_expression_up hsa-let-7i Neoplasms [unspecific] 18187804 "Changing the cellular levels of let-7i, mir-16, and mir-21 affected the potencies of a number of the anticancer agents by up to 4-fold." tissue_expression_up hsa-mir-16 Neoplasms [unspecific] 18187804 "Changing the cellular levels of let-7i, mir-16, and mir-21 affected the potencies of a number of the anticancer agents by up to 4-fold." tissue_expression_up hsa-mir-21 Neoplasms [unspecific] 18187804 "Changing the cellular levels of let-7i, mir-16, and mir-21 affected the potencies of a number of the anticancer agents by up to 4-fold." tissue_expression_up hsa-mir-21 "Carcinoma, Rectal" 18196926 "Expression levels of analyzed miRNAs significantly differed among tumors and adjacent non-tumor tissues: miR-21 (p = 0.0001) and miR-31 (p = 0.0006) were upregulated, and miR-143 (p = 0.011) and miR-145 (p = 0.003) were downregulated in tumors." tissue_expression_up hsa-mir-31 "Carcinoma, Rectal" 18196926 "Expression levels of analyzed miRNAs significantly differed among tumors and adjacent non-tumor tissues: miR-21 (p = 0.0001) and miR-31 (p = 0.0006) were upregulated, and miR-143 (p = 0.011) and miR-145 (p = 0.003) were downregulated in tumors." tissue_expression_up hsa-mir-203 Esophageal Neoplasms 18242245 Both mir_203 and mir_205 were expressed 2- to 10-fold lower in squamous cell carcinoma and adenocarcinomas than in normal epithelium. tissue_expression_up hsa-mir-205 Esophageal Neoplasms 18242245 Both mir_203 and mir_205 were expressed 2- to 10-fold lower in squamous cell carcinoma and adenocarcinomas than in normal epithelium. tissue_expression_up hsa-mir-100 "Carcinoma, Hepatocellular" 18307259 "miR-122, miR-100, and miR-10a were overexpressed whereas miR-198 and miR-145 were up to 5-fold down-regulated in hepatic tumors compared to normal liver parenchyma." tissue_expression_up hsa-mir-10a "Carcinoma, Hepatocellular" 18307259 "miR-122, miR-100, and miR-10a were overexpressed whereas miR-198 and miR-145 were up to 5-fold down-regulated in hepatic tumors compared to normal liver parenchyma." tissue_expression_up hsa-mir-122 "Carcinoma, Hepatocellular" 18307259 "miR-122, miR-100, and miR-10a were overexpressed whereas miR-198 and miR-145 were up to 5-fold down-regulated in hepatic tumors compared to normal liver parenchyma." tissue_expression_up hsa-mir-191 Neoplasms [unspecific] 18375788 increased tissue_expression_up hsa-mir-146a Rheumatoid Arthritis 18383392 This study provides the first description of increased expression of miRNA miR-155 and miR-146a in RA. tissue_expression_up hsa-mir-155 Rheumatoid Arthritis 18383392 This study provides the first description of increased expression of miRNA miR-155 and miR-146a in RA. tissue_expression_up hsa-mir-221 Neoplasms [unspecific] 18413744 "Thus, the physiologic up-regulation of miR-221 and miR-222 is tightly linked to a cell cycle checkpoint that ensures cell survival by coordinating competency for initiation of S phase with growth factor signaling pathways that stimulate cell proliferation." tissue_expression_up hsa-mir-222 Neoplasms [unspecific] 18413744 "Thus, the physiologic up-regulation of miR-221 and miR-222 is tightly linked to a cell cycle checkpoint that ensures cell survival by coordinating competency for initiation of S phase with growth factor signaling pathways that stimulate cell proliferation." tissue_expression_up hsa-mir-126 "Carcinoma, Hepatocellular" 18433021 "miR-96 was overexpressed in HBV tumors, and miR-126* was down-regulated in alcohol-related hepatocellular carcinoma." tissue_expression_up hsa-mir-141 Ovarian Neoplasms 18451233 Higher tissue_expression_up hsa-mir-18a Ovarian Neoplasms 18451233 Higher tissue_expression_up hsa-mir-429 Ovarian Neoplasms 18451233 Higher tissue_expression_up hsa-mir-93 Ovarian Neoplasms 18451233 Higher tissue_expression_up hsa-mir-150 Retinal Neovascularization 18500251 increased tissue_expression_up hsa-mir-184 Retinal Neovascularization 18500251 increased tissue_expression_up hsa-mir-31 Retinal Neovascularization 18500251 increased tissue_expression_up hsa-mir-451a Retinal Neovascularization 18500251 increased tissue_expression_up hsa-mir-21 Ovarian Neoplasms 18560586 "we identify several miRNAs aberrantly expressed in human ovarian cancer tissues and cell lines. miR-221 stands out as a highly elevated miRNA in ovarian cancer, while miR-21 and several members of the let-7 family are found downregulated." tissue_expression_up hsa-mir-146b Thyroid Neoplasms 18587330 miR-146b: overexpressed tissue_expression_up hsa-mir-221 Thyroid Neoplasms 18587330 miR-221: overexpressed tissue_expression_up hsa-mir-222 Thyroid Neoplasms 18587330 miR-222: overexpressed tissue_expression_up hsa-mir-146a Urinary Bladder Cancer 18596939 miR-146a: upregulated tissue_expression_up hsa-mir-155 Urinary Bladder Cancer 18596939 miR-155: upregulated tissue_expression_up hsa-mir-15b Urinary Bladder Cancer 18596939 miR-15b: upregulated tissue_expression_up hsa-mir-16-1 Urinary Bladder Cancer 18596939 miR-16: upregulated tissue_expression_up hsa-mir-16-2 Urinary Bladder Cancer 18596939 miR-16: upregulated tissue_expression_up hsa-mir-21 Pancreatic Neoplasms 18642050 miR-21: MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survival tissue_expression_up hsa-let-7f "Carcinoma, Pancreatic" 18665421 "In addition, when analyzed according to specific cancer phenotypes, miR-15a and miR-16 show a significant downregulation in canine ductal carcinomas while miRsR-181b, -21, -29b, and let-7f show a significant upregulation in canine tubular papillary carcinomas." tissue_expression_up hsa-mir-181b "Carcinoma, Pancreatic" 18665421 "In addition, when analyzed according to specific cancer phenotypes, miR-15a and miR-16 show a significant downregulation in canine ductal carcinomas while miRsR-181b, -21, -29b, and let-7f show a significant upregulation in canine tubular papillary carcinomas." tissue_expression_up hsa-mir-21 "Carcinoma, Pancreatic" 18665421 "In addition, when analyzed according to specific cancer phenotypes, miR-15a and miR-16 show a significant downregulation in canine ductal carcinomas while miRsR-181b, -21, -29b, and let-7f show a significant upregulation in canine tubular papillary carcinomas." tissue_expression_up hsa-mir-29b "Carcinoma, Pancreatic" 18665421 "In addition, when analyzed according to specific cancer phenotypes, miR-15a and miR-16 show a significant downregulation in canine ductal carcinomas while miRsR-181b, -21, -29b, and let-7f show a significant upregulation in canine tubular papillary carcinomas." tissue_expression_up hsa-mir-106b Prostate Neoplasms 18676839 miR-106b: significantly higher expression tissue_expression_up hsa-mir-25 Prostate Neoplasms 18676839 miR-25: significantly higher expression tissue_expression_up hsa-mir-32 Prostate Neoplasms 18676839 miR-32: significantly higher expression tissue_expression_up hsa-mir-93 Prostate Neoplasms 18676839 miR-93: significantly higher expression tissue_expression_up hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 18719201 miR-205: overexpression tissue_expression_up hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 18719201 miR-21: overexpression tissue_expression_up hsa-mir-146a Rheumatoid Arthritis 18759964 miR-146a: Upregulated miR-146a expression in peripheral blood mononuclear cells tissue_expression_up hsa-let-7a-1 Head And Neck Neoplasms 18798260 let-7a: overexpressed tissue_expression_up hsa-let-7a-2 Head And Neck Neoplasms 18798260 let-7a: overexpressed tissue_expression_up hsa-let-7a-3 Head And Neck Neoplasms 18798260 let-7a: overexpressed tissue_expression_up hsa-let-7b Head And Neck Neoplasms 18798260 let-7b: overexpressed tissue_expression_up hsa-let-7c Head And Neck Neoplasms 18798260 let-7c: overexpressed tissue_expression_up hsa-let-7d Head And Neck Neoplasms 18798260 let-7d: overexpressed tissue_expression_up hsa-let-7e Head And Neck Neoplasms 18798260 let-7e: overexpressed tissue_expression_up hsa-let-7f-1 Head And Neck Neoplasms 18798260 let-7f: overexpressed tissue_expression_up hsa-let-7f-2 Head And Neck Neoplasms 18798260 let-7f: overexpressed tissue_expression_up hsa-let-7g Head And Neck Neoplasms 18798260 let-7g: overexpressed tissue_expression_up hsa-let-7i Head And Neck Neoplasms 18798260 let-7i: overexpressed tissue_expression_up hsa-mir-142 Head And Neck Neoplasms 18798260 miR-142-3p: overexpressed tissue_expression_up hsa-mir-146b Head And Neck Neoplasms 18798260 miR-146b: overexpressed tissue_expression_up hsa-mir-155 Head And Neck Neoplasms 18798260 miR-155: overexpressed tissue_expression_up hsa-mir-18a Head And Neck Neoplasms 18798260 miR-18: overexpressed tissue_expression_up hsa-mir-18b Head And Neck Neoplasms 18798260 miR-18: overexpressed tissue_expression_up hsa-mir-21 Head And Neck Neoplasms 18798260 miR-21: overexpressed tissue_expression_up hsa-mir-29c Head And Neck Neoplasms 18798260 miR-29c: overexpressed tissue_expression_up hsa-mir-143 Obesity 18809385 miR-143: Up-regulated expression of microRNA-143 in association with obesity in adipose tissue_expression_up hsa-mir-204 Breast Neoplasms 18922924 miR-204: upregulated tissue_expression_up hsa-mir-510 Breast Neoplasms 18922924 miR-510: upregulated tissue_expression_up hsa-mir-135b Prostate Neoplasms 18949015 miR-135b: up-regulated tissue_expression_up hsa-mir-194-1 Prostate Neoplasms 18949015 miR-194: up-regulated tissue_expression_up hsa-mir-194-2 Prostate Neoplasms 18949015 miR-194: up-regulated tissue_expression_up hsa-mir-126 Ovarian Neoplasms 18954897 miR-126: over-expressed tissue_expression_up hsa-mir-21 Ovarian Neoplasms 18954897 miR-21: over-expressed tissue_expression_up hsa-mir-29a Ovarian Neoplasms 18954897 miR-29a: over-expressed tissue_expression_up hsa-mir-92b Ovarian Neoplasms 18954897 miR-92: over-expressed tissue_expression_up hsa-mir-93 Ovarian Neoplasms 18954897 miR-93: over-expressed tissue_expression_up hsa-mir-106a Gastric Neoplasms 18996365 "The level of miR-106a in cancer tissues was significantly higher than that in non-tumor tissues, with an average 1.625-fold increase. miR-106a level was significantly associated with tumor stage, size and differentiation; lymphatic and distant metastasis; and invasion (P<0.01)." tissue_expression_up hsa-mir-15b Pancreatic Neoplasms 19030927 miR-15b: upregulated tissue_expression_up hsa-mir-186 Pancreatic Neoplasms 19030927 miR-186: upregulated tissue_expression_up hsa-mir-190a Pancreatic Neoplasms 19030927 miR-190: upregulated tissue_expression_up hsa-mir-196a-1 Pancreatic Neoplasms 19030927 miR-196a: upregulated tissue_expression_up hsa-mir-196a-2 Pancreatic Neoplasms 19030927 miR-196a: upregulated tissue_expression_up hsa-mir-200b Pancreatic Neoplasms 19030927 miR-200b: upregulated tissue_expression_up hsa-mir-221 Pancreatic Neoplasms 19030927 miR-221: upregulated tissue_expression_up hsa-mir-222 Pancreatic Neoplasms 19030927 miR-222: upregulated tissue_expression_up hsa-mir-95 Pancreatic Neoplasms 19030927 miR-95: upregulated tissue_expression_up hsa-mir-221 "Carcinoma, Thyroid, Papillary" 19030936 Primary or mature miR-221 were overexpressed in PTC as compared with HT-ori3. tissue_expression_up hsa-mir-103a-1 "Adenocarcinoma, Endometrial" 19065659 miR-103: upregulated tissue_expression_up hsa-mir-103a-2 "Adenocarcinoma, Endometrial" 19065659 miR-103: upregulated tissue_expression_up hsa-mir-106a "Adenocarcinoma, Endometrial" 19065659 miR-106a: upregulated tissue_expression_up hsa-mir-151a "Adenocarcinoma, Endometrial" 19065659 miR-151: upregulated tissue_expression_up hsa-mir-155 "Adenocarcinoma, Endometrial" 19065659 miR-155: upregulated tissue_expression_up hsa-mir-182 "Adenocarcinoma, Endometrial" 19065659 miR-182: upregulated tissue_expression_up hsa-mir-183 "Adenocarcinoma, Endometrial" 19065659 miR-183: upregulated tissue_expression_up hsa-mir-194-1 "Adenocarcinoma, Endometrial" 19065659 miR-194: upregulated tissue_expression_up hsa-mir-194-2 "Adenocarcinoma, Endometrial" 19065659 miR-194: upregulated tissue_expression_up hsa-mir-200a "Adenocarcinoma, Endometrial" 19065659 miR-200a: upregulated tissue_expression_up hsa-mir-200c "Adenocarcinoma, Endometrial" 19065659 miR-200c: upregulated tissue_expression_up hsa-mir-203 "Adenocarcinoma, Endometrial" 19065659 miR-203: upregulated tissue_expression_up hsa-mir-205 "Adenocarcinoma, Endometrial" 19065659 miR-205: upregulated tissue_expression_up hsa-mir-210 "Adenocarcinoma, Endometrial" 19065659 miR-210: upregulated tissue_expression_up hsa-mir-223 "Adenocarcinoma, Endometrial" 19065659 miR-223: upregulated tissue_expression_up hsa-mir-95 "Adenocarcinoma, Endometrial" 19065659 miR-95: upregulated tissue_expression_up hsa-mir-100 Endometriosis 19074548 miR-100: upregulated tissue_expression_up hsa-mir-1-1 Endometriosis 19074548 miR-1: upregulated tissue_expression_up hsa-mir-1-2 Endometriosis 19074548 miR-1: upregulated tissue_expression_up hsa-mir-125a Endometriosis 19074548 miR-125a: upregulated tissue_expression_up hsa-mir-125b-1 Endometriosis 19074548 miR-125b: upregulated tissue_expression_up hsa-mir-125b-2 Endometriosis 19074548 miR-125b: upregulated tissue_expression_up hsa-mir-126 Endometriosis 19074548 miR-126: upregulated tissue_expression_up hsa-mir-143 Endometriosis 19074548 miR-143: upregulated tissue_expression_up hsa-mir-145 Endometriosis 19074548 miR-145: upregulated tissue_expression_up hsa-mir-150 Endometriosis 19074548 miR-150: upregulated tissue_expression_up hsa-mir-194-1 Endometriosis 19074548 miR-194: upregulated tissue_expression_up hsa-mir-194-2 Endometriosis 19074548 miR-194: upregulated tissue_expression_up hsa-mir-223 Endometriosis 19074548 miR-223: upregulated tissue_expression_up hsa-mir-29c Endometriosis 19074548 miR-29c: upregulated tissue_expression_up hsa-mir-365a Endometriosis 19074548 miR-365: upregulated tissue_expression_up hsa-mir-365b Endometriosis 19074548 miR-365: upregulated tissue_expression_up hsa-mir-99a Endometriosis 19074548 miR-99a: upregulated tissue_expression_up hsa-mir-99b Endometriosis 19074548 miR-99b: upregulated tissue_expression_up hsa-mir-205 "Adenocarcinoma, Endometrial" 19077565 miR-205: upregulated tissue_expression_up hsa-mir-429 "Adenocarcinoma, Endometrial" 19077565 miR-429: upregulated tissue_expression_up hsa-mir-449a "Adenocarcinoma, Endometrial" 19077565 miR-449: upregulated tissue_expression_up hsa-mir-449b "Adenocarcinoma, Endometrial" 19077565 miR-449: upregulated tissue_expression_up hsa-mir-21 Breast Ductal Carcinoma 19080492 miR-21: expression is significantly higher than the normal controls tissue_expression_up hsa-mir-223 Ischemia-Reperfusion Injury 19104939 miR-223: miR-223 expression levels were greatly up-regulated in the livers after 75 min ischemia followed by 120 min reperfusion when compared to sham controls tissue_expression_up hsa-mir-210 Neoplasms [unspecific] 19141645 "two miRs, miR-210 and miR-373, are up-regulated in a hypoxia-inducible factor-1alpha-dependent manner in hypoxic cells" tissue_expression_up hsa-mir-373 Neoplasms [unspecific] 19141645 "two miRs, miR-210 and miR-373, are up-regulated in a hypoxia-inducible factor-1alpha-dependent manner in hypoxic cells" tissue_expression_up hsa-mir-150 Gastric Neoplasms 19148490 miR-150: patients with high expression levels have lower survival time tissue_expression_up hsa-mir-20b Gastric Neoplasms 19148490 miR-20b: patients with high expression levels have lower survival time tissue_expression_up hsa-mir-34b Gastric Neoplasms 19148490 miR-34b: upregulated in undifferentiated gastric cancer tissue_expression_up hsa-mir-34c Gastric Neoplasms 19148490 miR-34c: upregulated in undifferentiated gastric cancer tissue_expression_up hsa-mir-21 Astrocytoma 19159078 miR-21: upregulation tissue_expression_up hsa-mir-221 Astrocytoma 19159078 miR-221: upregulation tissue_expression_up hsa-mir-155 Neoplasms [unspecific] 19175697 "The expression of a subset of miRs (e.g. miR-21 and miR-155) was found to be consistently up-regulated, whereas another subset of miRs (e.g.miR-143 and miR-145) was consistently down-regulated across different cancer types suggesting their involvement in regulating common cellular processes whose deregulation may lead to tumourigenesis." tissue_expression_up hsa-mir-21 Neoplasms [unspecific] 19175697 "The expression of a subset of miRs (e.g. miR-21 and miR-155) was found to be consistently up-regulated, whereas another subset of miRs (e.g.miR-143 and miR-145) was consistently down-regulated across different cancer types suggesting their involvement in regulating common cellular processes whose deregulation may lead to tumourigenesis." tissue_expression_up hsa-mir-106b Gastric Neoplasms 19175831 miR-106b: overexpressed tissue_expression_up hsa-mir-17 Gastric Neoplasms 19175831 miR-17: overexpressed tissue_expression_up hsa-mir-18a Gastric Neoplasms 19175831 miR-18a: overexpressed tissue_expression_up hsa-mir-18b Gastric Neoplasms 19175831 miR-18b: overexpressed tissue_expression_up hsa-mir-19a Gastric Neoplasms 19175831 miR-19a: overexpressed tissue_expression_up hsa-mir-20a Gastric Neoplasms 19175831 miR-20a: overexpressed tissue_expression_up hsa-mir-20b Gastric Neoplasms 19175831 miR-20b: overexpressed tissue_expression_up hsa-mir-21 Gastric Neoplasms 19175831 miR-21: overexpressed tissue_expression_up hsa-mir-340 Gastric Neoplasms 19175831 miR-340*: overexpressed tissue_expression_up hsa-mir-421 Gastric Neoplasms 19175831 miR-421: overexpressed tissue_expression_up hsa-mir-658 Gastric Neoplasms 19175831 miR-658: overexpressed tissue_expression_up hsa-mir-21 Head And Neck Neoplasms 19179615 miR-21: is frequently overexpressed in human HNSCC tissue_expression_up hsa-mir-146a Hepatitis B Virus Infection 19187610 miR-146a: up-regulated tissue_expression_up hsa-mir-181a-2 Hepatitis B Virus Infection 19187610 miR-181a: up-regulated tissue_expression_up hsa-mir-181b-1 Hepatitis B Virus Infection 19187610 miR-181b: up-regulated tissue_expression_up hsa-mir-181b-2 Hepatitis B Virus Infection 19187610 miR-181b: up-regulated tissue_expression_up hsa-mir-200a Hepatitis B Virus Infection 19187610 miR-200: up-regulated tissue_expression_up hsa-mir-200b Hepatitis B Virus Infection 19187610 miR-200: up-regulated tissue_expression_up hsa-mir-200c Hepatitis B Virus Infection 19187610 miR-200: up-regulated tissue_expression_up hsa-mir-17 Colorectal Carcinoma 19201770 miR-17-3p: up-regulated both in plasma and tissue samples tissue_expression_up hsa-mir-21 Breast Neoplasms 19212625 "miR-21: upregulated, The expression levels of miR-21 were correlated with PTEN and commonly used clinicopathologic features of breast cancer" tissue_expression_up hsa-mir-155 "Carcinoma, Renal Cell" 19228262 miR-155: overexpressed in malignant cancer than non-malignant one tissue_expression_up hsa-mir-16-1 "Carcinoma, Renal Cell" 19228262 miR-16: overexpressed in malignant cancer than non-malignant one tissue_expression_up hsa-mir-16-2 "Carcinoma, Renal Cell" 19228262 miR-16: overexpressed in malignant cancer than non-malignant one tissue_expression_up hsa-mir-210 "Carcinoma, Renal Cell" 19228262 miR-210: overexpressed in malignant cancer than non-malignant one tissue_expression_up hsa-mir-224 "Carcinoma, Renal Cell" 19228262 miR-224: overexpressed in malignant cancer than non-malignant one tissue_expression_up hsa-mir-452 "Carcinoma, Renal Cell" 19228262 miR-452*: overexpressed in malignant cancer than non-malignant one tissue_expression_up hsa-mir-21 Esophageal Neoplasms 19276261 "miR-21: overexpressed compared with with matched normal epitheliums, regulates the proliferation and invasion" tissue_expression_up hsa-mir-143 Endotoxemia 19284987 "Data analysis revealed that five miRNAs consistently responded to LPS-infusion, four of which were down-regulated (miR-146b, miR-150, miR-342, and let-7g) and one was up-regulated (miR-143). The miR-150 and mir-342 response was confirmed by real-time PCR." tissue_expression_up hsa-mir-17 Colorectal Carcinoma 19287964 miR-17-5p: up-regulated tissue_expression_up hsa-mir-183 Colorectal Carcinoma 19287964 miR-183: up-regulated tissue_expression_up hsa-mir-18a Colorectal Carcinoma 19287964 miR-18a: up-regulated tissue_expression_up hsa-mir-20a Colorectal Carcinoma 19287964 miR-20a: up-regulated tissue_expression_up hsa-mir-31 Colorectal Carcinoma 19287964 miR-31: up-regulated tissue_expression_up hsa-mir-92b Colorectal Carcinoma 19287964 miR-92: up-regulated tissue_expression_up hsa-mir-155 Breast Neoplasms 19290006 "Compared with normal breast samples, a panel of miRs was consistently dysregulated in breast cancer, including earlier-reported breast cancer-related miRs, such as upregulated miR-21, miR-155, miR-191, and miR-196a, and downregulated miR-125b and miR-221." tissue_expression_up hsa-mir-191 Breast Neoplasms 19290006 "Compared with normal breast samples, a panel of miRs was consistently dysregulated in breast cancer, including earlier-reported breast cancer-related miRs, such as upregulated miR-21, miR-155, miR-191, and miR-196a, and downregulated miR-125b and miR-221." tissue_expression_up hsa-mir-196a Breast Neoplasms 19290006 "Compared with normal breast samples, a panel of miRs was consistently dysregulated in breast cancer, including earlier-reported breast cancer-related miRs, such as upregulated miR-21, miR-155, miR-191, and miR-196a, and downregulated miR-125b and miR-221." tissue_expression_up hsa-mir-21 Breast Neoplasms 19290006 "Compared with normal breast samples, a panel of miRs was consistently dysregulated in breast cancer, including earlier-reported breast cancer-related miRs, such as upregulated miR-21, miR-155, miR-191, and miR-196a, and downregulated miR-125b and miR-221." tissue_expression_up hsa-mir-21 Cholangiocarcinoma 19296468 miR-21: overexpressed tissue_expression_up hsa-mir-299 Primary Biliary Cirrhosis 19345069 A total of 35 independent miRNAs were found to be differentially expressed in PBC (p < 0.001).Quantitative PCR was employed to validate down-regulation of microRNA-122a (miR-122a) and miR-26a and the increased expression of miR-328 and miR-299-5p. tissue_expression_up hsa-mir-328 Primary Biliary Cirrhosis 19345069 A total of 35 independent miRNAs were found to be differentially expressed in PBC (p < 0.001).Quantitative PCR was employed to validate down-regulation of microRNA-122a (miR-122a) and miR-26a and the increased expression of miR-328 and miR-299-5p. tissue_expression_up hsa-mir-140 Salivary Gland Neoplasms 19347935 miR-140: up-regulated tissue_expression_up hsa-mir-154 Salivary Gland Neoplasms 19347935 miR-154: up-regulated tissue_expression_up hsa-mir-188 Salivary Gland Neoplasms 19347935 miR-188: up-regulated tissue_expression_up hsa-mir-21 Salivary Gland Neoplasms 19347935 miR-21: up-regulated tissue_expression_up hsa-mir-23b Salivary Gland Neoplasms 19347935 miR-23b: up-regulated tissue_expression_up hsa-mir-299 Salivary Gland Neoplasms 19347935 miR-299-3p: up-regulated tissue_expression_up hsa-mir-29c Salivary Gland Neoplasms 19347935 miR-29c: up-regulated tissue_expression_up hsa-mir-301a Salivary Gland Neoplasms 19347935 miR-301: up-regulated tissue_expression_up hsa-mir-301b Salivary Gland Neoplasms 19347935 miR-301: up-regulated tissue_expression_up hsa-mir-302c Salivary Gland Neoplasms 19347935 miR-302c: up-regulated tissue_expression_up hsa-mir-337 Salivary Gland Neoplasms 19347935 miR-337: up-regulated tissue_expression_up hsa-mir-376a-1 Salivary Gland Neoplasms 19347935 miR-376a: up-regulated tissue_expression_up hsa-mir-376a-2 Salivary Gland Neoplasms 19347935 miR-376a: up-regulated tissue_expression_up hsa-mir-409 Salivary Gland Neoplasms 19347935 miR-409-3p: up-regulated tissue_expression_up hsa-mir-449a Salivary Gland Neoplasms 19347935 miR-449: up-regulated tissue_expression_up hsa-mir-449b Salivary Gland Neoplasms 19347935 miR-449: up-regulated tissue_expression_up hsa-mir-495 Salivary Gland Neoplasms 19347935 miR-495: up-regulated tissue_expression_up hsa-mir-99b Salivary Gland Neoplasms 19347935 miR-99b: up-regulated tissue_expression_up hsa-mir-130b Head And Neck Neoplasms 19351747 miR-130b: up-regulated tissue_expression_up hsa-mir-181a-2 Head And Neck Neoplasms 19351747 miR-181a: up-regulated tissue_expression_up hsa-mir-181b-1 Head And Neck Neoplasms 19351747 miR-181b: up-regulated tissue_expression_up hsa-mir-181b-2 Head And Neck Neoplasms 19351747 miR-181b: up-regulated tissue_expression_up hsa-mir-181d Head And Neck Neoplasms 19351747 miR-181d: up-regulated tissue_expression_up hsa-mir-18a Head And Neck Neoplasms 19351747 miR-18a: up-regulated tissue_expression_up hsa-mir-193b Head And Neck Neoplasms 19351747 miR-193b: up-regulated tissue_expression_up hsa-mir-21 Head And Neck Neoplasms 19351747 miR-21: up-regulated tissue_expression_up hsa-mir-221 Head And Neck Neoplasms 19351747 miR-221: up-regulated tissue_expression_up hsa-mir-455 Head And Neck Neoplasms 19351747 miR-455: up-regulated tissue_expression_up hsa-mir-491 Head And Neck Neoplasms 19351747 miR-491: up-regulated tissue_expression_up hsa-let-7a-1 "Carcinoma, Adrenocortical" 19351815 let-7a: upregulated tissue_expression_up hsa-let-7a-2 "Carcinoma, Adrenocortical" 19351815 let-7a: upregulated tissue_expression_up hsa-let-7a-3 "Carcinoma, Adrenocortical" 19351815 let-7a: upregulated tissue_expression_up hsa-let-7b "Carcinoma, Adrenocortical" 19351815 let-7b: upregulated tissue_expression_up hsa-let-7c "Carcinoma, Adrenocortical" 19351815 let-7c: upregulated tissue_expression_up hsa-let-7d "Carcinoma, Adrenocortical" 19351815 let-7d: upregulated tissue_expression_up hsa-mir-100 "Carcinoma, Adrenocortical" 19351815 miR-100: upregulated tissue_expression_up hsa-mir-1-1 "Carcinoma, Adrenocortical" 19351815 miR-1: upregulated tissue_expression_up hsa-mir-1-2 "Carcinoma, Adrenocortical" 19351815 miR-1: upregulated tissue_expression_up hsa-mir-125b-1 "Carcinoma, Adrenocortical" 19351815 miR-125b: upregulated tissue_expression_up hsa-mir-125b-2 "Carcinoma, Adrenocortical" 19351815 miR-125b: upregulated tissue_expression_up hsa-mir-126 "Carcinoma, Adrenocortical" 19351815 miR-126: upregulated tissue_expression_up hsa-mir-130a "Carcinoma, Adrenocortical" 19351815 miR-130a: upregulated tissue_expression_up hsa-mir-132 "Carcinoma, Adrenocortical" 19351815 miR-132: upregulated tissue_expression_up hsa-mir-133a-1 "Carcinoma, Adrenocortical" 19351815 miR-133a: upregulated tissue_expression_up hsa-mir-133a-2 "Carcinoma, Adrenocortical" 19351815 miR-133a: upregulated tissue_expression_up hsa-mir-135a-1 "Carcinoma, Adrenocortical" 19351815 miR-135a: upregulated tissue_expression_up hsa-mir-135a-2 "Carcinoma, Adrenocortical" 19351815 miR-135a: upregulated tissue_expression_up hsa-mir-137 "Carcinoma, Adrenocortical" 19351815 miR-137: upregulated tissue_expression_up hsa-mir-143 "Carcinoma, Adrenocortical" 19351815 miR-143: upregulated tissue_expression_up hsa-mir-145 "Carcinoma, Adrenocortical" 19351815 miR-145: upregulated tissue_expression_up hsa-mir-146a "Carcinoma, Adrenocortical" 19351815 miR-146a: upregulated tissue_expression_up hsa-mir-155 "Carcinoma, Adrenocortical" 19351815 miR-155: upregulated tissue_expression_up hsa-mir-15b "Carcinoma, Adrenocortical" 19351815 miR-15b: upregulated tissue_expression_up hsa-mir-16-1 "Carcinoma, Adrenocortical" 19351815 miR-16: upregulated tissue_expression_up hsa-mir-16-2 "Carcinoma, Adrenocortical" 19351815 miR-16: upregulated tissue_expression_up hsa-mir-17 "Carcinoma, Adrenocortical" 19351815 miR-17-5p: upregulated tissue_expression_up hsa-mir-192 "Carcinoma, Adrenocortical" 19351815 miR-192: upregulated tissue_expression_up hsa-mir-194-1 "Carcinoma, Adrenocortical" 19351815 miR-194: upregulated tissue_expression_up hsa-mir-194-2 "Carcinoma, Adrenocortical" 19351815 miR-194: upregulated tissue_expression_up hsa-mir-200b "Carcinoma, Adrenocortical" 19351815 miR-200b: upregulated tissue_expression_up hsa-mir-200c "Carcinoma, Adrenocortical" 19351815 miR-200c: upregulated tissue_expression_up hsa-mir-203 "Carcinoma, Adrenocortical" 19351815 miR-203: upregulated tissue_expression_up hsa-mir-222 "Carcinoma, Adrenocortical" 19351815 miR-222: upregulated tissue_expression_up hsa-mir-23b "Carcinoma, Adrenocortical" 19351815 miR-23b: upregulated tissue_expression_up hsa-mir-28 "Carcinoma, Adrenocortical" 19351815 miR-28: upregulated tissue_expression_up hsa-mir-30a "Carcinoma, Adrenocortical" 19351815 miR-30a-3p: upregulated tissue_expression_up hsa-mir-335 "Carcinoma, Adrenocortical" 19351815 miR-335: upregulated tissue_expression_up hsa-mir-375 "Carcinoma, Adrenocortical" 19351815 miR-375: upregulated tissue_expression_up hsa-mir-449a "Carcinoma, Adrenocortical" 19351815 miR-449: upregulated tissue_expression_up hsa-mir-449b "Carcinoma, Adrenocortical" 19351815 miR-449: upregulated tissue_expression_up hsa-mir-7-1 "Carcinoma, Adrenocortical" 19351815 miR-7: upregulated tissue_expression_up hsa-mir-7-2 "Carcinoma, Adrenocortical" 19351815 miR-7: upregulated tissue_expression_up hsa-mir-7-3 "Carcinoma, Adrenocortical" 19351815 miR-7: upregulated tissue_expression_up hsa-mir-221 Prostate Neoplasms 19351832 miR-221: Overexpression tissue_expression_up hsa-mir-222 Prostate Neoplasms 19351832 miR-222: Overexpression tissue_expression_up hsa-mir-100 "Carcinoma, Hepatocellular" 19360909 miR-100: overexpressed In HCC patients with hepatitis C and liver cirrhosis tissue_expression_up hsa-mir-10a "Carcinoma, Hepatocellular" 19360909 miR-10a: overexpressed In HCC patients with hepatitis C and liver cirrhosis tissue_expression_up hsa-mir-203 "Carcinoma, Hepatocellular" 19360909 miR-203: up-regulated in HCC compared to benign hepatocellular tumors tissue_expression_up hsa-mir-21 "Carcinoma, Hepatocellular" 19360909 miR-21: up-regulated in HCC compared to benign hepatocellular tumors tissue_expression_up hsa-mir-221 "Carcinoma, Hepatocellular" 19360909 miR-221: up-regulated in HCC compared to benign hepatocellular tumors tissue_expression_up hsa-mir-222 "Carcinoma, Hepatocellular" 19360909 miR-222: up-regulated in HCC compared to benign hepatocellular tumors tissue_expression_up hsa-mir-224 "Carcinoma, Hepatocellular" 19360909 miR-224: up-regulated in HCC compared to benign hepatocellular tumors tissue_expression_up hsa-mir-34a "Carcinoma, Hepatocellular" 19360909 miR-34a: up-regulated in HCC compared to benign hepatocellular tumors tissue_expression_up hsa-mir-342 Breast Neoplasms 19432961 MiR-342 expression was highest in ER and HER2/neu-positive luminal B tumours and lowest in triple-negative tumours. MiR-520g expression was elevated in ER and PR-negative tumours. tissue_expression_up hsa-mir-520g Breast Neoplasms 19432961 MiR-342 expression was highest in ER and HER2/neu-positive luminal B tumours and lowest in triple-negative tumours. MiR-520g expression was elevated in ER and PR-negative tumours. tissue_expression_up hsa-mir-27a Ovarian Neoplasms 19446316 High expression of hsa-mir-27a identified a sub-group of patients with very poor prognosis. tissue_expression_up hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 19446359 Mir-21 expression in the sputum specimens was significantly higher in cancer patients (76.32+/-9.79) than cancer-free individuals (62.24+/-3.82) (P<0.0001). tissue_expression_up hsa-mir-335 Obesity 19460359 These findings provide the first evidence that the up-regulated expressions of miR-335 in liver and WAT of obese mice might contribute to the pathophysiology of obesity. tissue_expression_up hsa-mir-150 Inflammation 19525145 "Specifically, recent studies indicate that those miRNAs that are selectively and/or highly expressed in immune cells including the miR-17-92 cluster, miR-150, miR-155, miR-181 and miR-223 have a 'permissive' function in the maturation, proliferation and differentiation of myeloid and lymphoid cells." tissue_expression_up hsa-mir-155 Inflammation 19525145 "Specifically, recent studies indicate that those miRNAs that are selectively and/or highly expressed in immune cells including the miR-17-92 cluster, miR-150, miR-155, miR-181 and miR-223 have a 'permissive' function in the maturation, proliferation and differentiation of myeloid and lymphoid cells." tissue_expression_up hsa-mir-17 Inflammation 19525145 "Specifically, recent studies indicate that those miRNAs that are selectively and/or highly expressed in immune cells including the miR-17-92 cluster, miR-150, miR-155, miR-181 and miR-223 have a 'permissive' function in the maturation, proliferation and differentiation of myeloid and lymphoid cells." tissue_expression_up hsa-mir-18 Inflammation 19525145 "Specifically, recent studies indicate that those miRNAs that are selectively and/or highly expressed in immune cells including the miR-17-92 cluster, miR-150, miR-155, miR-181 and miR-223 have a 'permissive' function in the maturation, proliferation and differentiation of myeloid and lymphoid cells." tissue_expression_up hsa-mir-181 Inflammation 19525145 "Specifically, recent studies indicate that those miRNAs that are selectively and/or highly expressed in immune cells including the miR-17-92 cluster, miR-150, miR-155, miR-181 and miR-223 have a 'permissive' function in the maturation, proliferation and differentiation of myeloid and lymphoid cells." tissue_expression_up hsa-mir-19a Inflammation 19525145 "Specifically, recent studies indicate that those miRNAs that are selectively and/or highly expressed in immune cells including the miR-17-92 cluster, miR-150, miR-155, miR-181 and miR-223 have a 'permissive' function in the maturation, proliferation and differentiation of myeloid and lymphoid cells." tissue_expression_up hsa-mir-19b-1 Inflammation 19525145 "Specifically, recent studies indicate that those miRNAs that are selectively and/or highly expressed in immune cells including the miR-17-92 cluster, miR-150, miR-155, miR-181 and miR-223 have a 'permissive' function in the maturation, proliferation and differentiation of myeloid and lymphoid cells." tissue_expression_up hsa-mir-20a Inflammation 19525145 "Specifically, recent studies indicate that those miRNAs that are selectively and/or highly expressed in immune cells including the miR-17-92 cluster, miR-150, miR-155, miR-181 and miR-223 have a 'permissive' function in the maturation, proliferation and differentiation of myeloid and lymphoid cells." tissue_expression_up hsa-mir-223 Inflammation 19525145 "Specifically, recent studies indicate that those miRNAs that are selectively and/or highly expressed in immune cells including the miR-17-92 cluster, miR-150, miR-155, miR-181 and miR-223 have a 'permissive' function in the maturation, proliferation and differentiation of myeloid and lymphoid cells." tissue_expression_up hsa-mir-92-1 Inflammation 19525145 "Specifically, recent studies indicate that those miRNAs that are selectively and/or highly expressed in immune cells including the miR-17-92 cluster, miR-150, miR-155, miR-181 and miR-223 have a 'permissive' function in the maturation, proliferation and differentiation of myeloid and lymphoid cells." tissue_expression_up hsa-mir-30a "Squamous Cell Carcinoma, Esophageal" 19536617 high expression levels; might play a important role in the development of the cancer tissue_expression_up hsa-mir-210 Adrenal Cortex Neoplasms 19546168 significantly higher expressed tissue_expression_up hsa-mir-503 Adrenal Cortex Neoplasms 19546168 significantly higher expressed tissue_expression_up hsa-mir-15a Pancreatic Neoplasms 19551852 differentially expressed; associates with poorer survival tissue_expression_up hsa-mir-203 Pancreatic Neoplasms 19551852 differentially expressed; associates with poorer survival tissue_expression_up hsa-mir-210 Pancreatic Neoplasms 19551852 differentially expressed; associates with poorer survival tissue_expression_up hsa-mir-222 Pancreatic Neoplasms 19551852 differentially expressed; associates with poorer survival tissue_expression_up hsa-mir-1224 Fatty Liver [unspecific] 19572984 expression increased after Lieber-DeCarli or MCD; tissue_expression_up hsa-mir-182 Fatty Liver [unspecific] 19572984 expression increased after Lieber-DeCarli or MCD; tissue_expression_up hsa-mir-146a Melanoma 19578755 overexpressed tissue_expression_up hsa-mir-17 Melanoma 19578755 miR-17-5p; overexpressed tissue_expression_up hsa-mir-18a Melanoma 19578755 overexpressed tissue_expression_up hsa-mir-20a Melanoma 19578755 overexpressed tissue_expression_up hsa-mir-155 Myocardial Infarction 19581315 "Overexpressed; arrhythmogenic miR-1, contributing to ischaemic arrhythmogenesis stimulated by beta-adrenergic pathway; downregulatied by propranolol together with SRF" tissue_expression_up hsa-mir-221 "Carcinoma, Hepatocellular" 19585654 critical player; up-regulated; could directly target hepatic transcriptional regulators of differentiation and an inhibitor of Wnt/beta-catenin signaling tissue_expression_up hsa-mir-17 Lung Neoplasms 19597473 miR-17-5p ; frequent overexpression tissue_expression_up hsa-mir-20a Lung Neoplasms 19597473 miR-17-92 overexpression may serve as a fine-tuning influence to counterbalance the generation of DNA damage tissue_expression_up hsa-mir-18a Breast Neoplasms 19624877 Differential expression profiles of microRNAs between breast cancer cells and mammary epithelial cells: mir-18a and mir-195 were highly expressed in MCF-7 cells; target genes of mir-200b were predicted by informatics analysis. tissue_expression_up hsa-mir-200b Breast Neoplasms 19624877 Differential expression profiles of microRNAs between breast cancer cells and mammary epithelial cells: mir-18a and mir-195 were highly expressed in MCF-7 cells; target genes of mir-200b were predicted by informatics analysis. tissue_expression_up hsa-mir-223 Breast Neoplasms 19624877 Differential expression profiles of microRNAs between breast cancer cells and mammary epithelial cells: mir-18a and mir-195 were highly expressed in MCF-7 cells; target genes of mir-200b were predicted by informatics analysis. tissue_expression_up hsa-mir-195 Eclampsia 19642860 increased in placenta tissue_expression_up hsa-mir-21 Eclampsia 19642860 increased in placenta tissue_expression_up hsa-mir-222 Eclampsia 19642860 increased in placenta tissue_expression_up hsa-mir-26b Eclampsia 19642860 increased in placenta tissue_expression_up hsa-mir-335 Eclampsia 19642860 increased in placenta tissue_expression_up hsa-mir-155 Neoplasms [unspecific] 19652553 "overexpression, target MYC antagonist MNT" tissue_expression_up hsa-mir-137 Colon Neoplasms 19659786 "expressed differently, miR-137 upregulated in non-cancerous colonic tissues from colon cancer patients with lymph node metastasis" tissue_expression_up hsa-mir-221 Cholesteatoma 19672202 up-regulated concurrent with down-regulation of PTEN tissue_expression_up hsa-mir-21 "Adenocarcinoma, Colon" 19672269 expression Increased tissue_expression_up hsa-mir-183 Neoplasms [unspecific] 19676045 up-regulated tissue_expression_up hsa-mir-96 Neoplasms [unspecific] 19676045 up-regulated tissue_expression_up hsa-mir-21 Alzheimer Disease 19683563 "up-regulated, inhibits bcl2 translation" tissue_expression_up hsa-mir-18a Breast Neoplasms 19684618 higher levels of expression in ERalpha-negative tumors tissue_expression_up hsa-mir-34a Breast Neoplasms 19684618 higher levels of expression in ERalpha-negative tumors tissue_expression_up hsa-mir-107 "Diabetes Mellitus, Type 2" 19689793 over-expressed in insulin target tissues tissue_expression_up hsa-mir-125a Hepatoblastoma 19701500 upregulated tissue_expression_up hsa-mir-150 Hepatoblastoma 19701500 upregulated tissue_expression_up hsa-mir-214 Hepatoblastoma 19701500 upregulated tissue_expression_up hsa-mir-208a Cardiomegaly 19726871 overexpression tissue_expression_up hsa-mir-155 "Leukemia, Myeloid, Acute" 19744129 "Their aberrant expression has been associated with solid tumors and hematopoietic malignancies as suggested by the frequent deletion of mir-15a and mir-16-1 in chronic lymphocytic leukemia, the increased levels of mir-155 in diffuse large B-cell lymphomas and the increased levels of mir-181 in acute myeloid leukemia M1 and M2. " tissue_expression_up hsa-mir-155 "Lymphoma, Large B-Cell, Diffuse" 19744129 "Their aberrant expression has been associated with solid tumors and hematopoietic malignancies as suggested by the frequent deletion of mir-15a and mir-16-1 in chronic lymphocytic leukemia, the increased levels of mir-155 in diffuse large B-cell lymphomas and the increased levels of mir-181 in acute myeloid leukemia M1 and M2. " tissue_expression_up hsa-mir-130a Lung Neoplasms 19748927 "miR-21, mir-31, miR-130a, miR-146b and miR-377 were consistently upregulated, whereas miR-1 and miR-143 were downregulated in lung tumors relative to normal lungs." tissue_expression_up hsa-mir-146b Lung Neoplasms 19748927 "miR-21, mir-31, miR-130a, miR-146b and miR-377 were consistently upregulated, whereas miR-1 and miR-143 were downregulated in lung tumors relative to normal lungs." tissue_expression_up hsa-mir-21 Lung Neoplasms 19748927 "miR-21, mir-31, miR-130a, miR-146b and miR-377 were consistently upregulated, whereas miR-1 and miR-143 were downregulated in lung tumors relative to normal lungs." tissue_expression_up hsa-mir-31 Lung Neoplasms 19748927 "miR-21, mir-31, miR-130a, miR-146b and miR-377 were consistently upregulated, whereas miR-1 and miR-143 were downregulated in lung tumors relative to normal lungs." tissue_expression_up hsa-mir-377 Lung Neoplasms 19748927 "miR-21, mir-31, miR-130a, miR-146b and miR-377 were consistently upregulated, whereas miR-1 and miR-143 were downregulated in lung tumors relative to normal lungs." tissue_expression_up hsa-mir-192 Squamous Cell Carcinoma 19789312 "In adenocarcinoma patients, miR-21, miR-223, miR-192, and miR-194 expression was elevated, whereas miR-203 expression was reduced in cancerous compared with noncancerous tissue." tissue_expression_up hsa-mir-194 Squamous Cell Carcinoma 19789312 "In adenocarcinoma patients, miR-21, miR-223, miR-192, and miR-194 expression was elevated, whereas miR-203 expression was reduced in cancerous compared with noncancerous tissue." tissue_expression_up hsa-mir-21 Squamous Cell Carcinoma 19789312 "In adenocarcinoma patients, miR-21, miR-223, miR-192, and miR-194 expression was elevated, whereas miR-203 expression was reduced in cancerous compared with noncancerous tissue." tissue_expression_up hsa-mir-223 Squamous Cell Carcinoma 19789312 "In adenocarcinoma patients, miR-21, miR-223, miR-192, and miR-194 expression was elevated, whereas miR-203 expression was reduced in cancerous compared with noncancerous tissue." tissue_expression_up hsa-mir-29a Lung Neoplasms 19818597 "MiRNA expression profiling of human NSCLC cell lines indicated that miR-29a levels were reduced in more invasive cell lines. Exogenous overexpression of miR-29a in both lung and pancreatic cancer cell lines resulted in a significant reduction in the invasion phenotype, as well as in proliferation." tissue_expression_up hsa-mir-15b Melanoma 19830692 "MiR-15b:MiR-15b and miR-210 were significantly upregulated, miR-34a was significantly downregulated in melanomas" tissue_expression_up hsa-mir-210 Melanoma 19830692 "miR-210:MiR-15b and miR-210 were significantly upregulated, miR-34a was significantly downregulated in melanomas" tissue_expression_up hsa-mir-210 Adrenal Cortex Neoplasms 19849700 up-regulated tissue_expression_up hsa-mir-484 Adrenal Cortex Neoplasms 19849700 up-regulated tissue_expression_up hsa-mir-193b Hematologic Neoplasms 19883314 miR-193b-365 significantly up-regulated in MM tissue_expression_up hsa-mir-200a "Adenocarcinoma, Endometrial" 19891660 up-regulated tissue_expression_up hsa-mir-200b "Adenocarcinoma, Endometrial" 19891660 up-regulated tissue_expression_up hsa-mir-205 "Adenocarcinoma, Endometrial" 19891660 up-regulated tissue_expression_up hsa-mir-141 Nephrosclerosis 19910931 significantly higher in patients with hypertensive nephrosclerosis than controls tissue_expression_up hsa-mir-192 Nephrosclerosis 19910931 significantly higher in patients with hypertensive nephrosclerosis than controls tissue_expression_up hsa-mir-200a Nephrosclerosis 19910931 significantly higher in patients with hypertensive nephrosclerosis than controls tissue_expression_up hsa-mir-200b Nephrosclerosis 19910931 significantly higher in patients with hypertensive nephrosclerosis than controls tissue_expression_up hsa-mir-205 Nephrosclerosis 19910931 significantly higher in patients with hypertensive nephrosclerosis than controls tissue_expression_up hsa-mir-429 Nephrosclerosis 19910931 significantly higher in patients with hypertensive nephrosclerosis than controls tissue_expression_up hsa-mir-223 Rheumatoid Arthritis 19931339 miR-223 is overexpressed in T-lymphocytes of patients affected by rheumatoid arthritis. tissue_expression_up hsa-mir-17 "Lymphoma, B-Cell" 19945163 miR-17-5p:the detection of upregulation of miR-17-5p and miR-181a in B- and T-cell lymphomas respectively tissue_expression_up hsa-mir-17 "Lymphoma, T-Cell" 19945163 miR-17-5p:the detection of upregulation of miR-17-5p and miR-181a in B- and T-cell lymphomas respectively tissue_expression_up hsa-mir-181a-1 "Lymphoma, B-Cell" 19945163 miR-181a:the detection of upregulation of miR-17-5p and miR-181a in B- and T-cell lymphomas respectively tissue_expression_up hsa-mir-181a-1 "Lymphoma, T-Cell" 19945163 miR-181a:the detection of upregulation of miR-17-5p and miR-181a in B- and T-cell lymphomas respectively tissue_expression_up hsa-mir-181a-2 "Lymphoma, B-Cell" 19945163 miR-181a:the detection of upregulation of miR-17-5p and miR-181a in B- and T-cell lymphomas respectively tissue_expression_up hsa-mir-181a-2 "Lymphoma, T-Cell" 19945163 miR-181a:the detection of upregulation of miR-17-5p and miR-181a in B- and T-cell lymphomas respectively tissue_expression_up hsa-mir-629 Breast Neoplasms 19946373 upregulated tissue_expression_up hsa-mir-629 Colon Neoplasms 19946373 upregulated tissue_expression_up hsa-mir-629 Liver Neoplasms 19946373 upregulated tissue_expression_up hsa-mir-629 Lung Neoplasms 19946373 upregulated tissue_expression_up hsa-mir-629 Lymphoma 19946373 upregulated tissue_expression_up hsa-mir-629 Ovarian Neoplasms 19946373 upregulated tissue_expression_up hsa-mir-629 Prostate Neoplasms 19946373 upregulated tissue_expression_up hsa-mir-629 Testicular Neoplasms 19946373 upregulated tissue_expression_up hsa-mir-214 Gastric Neoplasms 20022810 high expression tissue_expression_up hsa-mir-125a Retinal Degeneration 20053268 Over-expression tissue_expression_up hsa-mir-204 Retinal Degeneration 20053268 Over-expression tissue_expression_up hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 20068099 hsa-miR-205 is a miRNA that is highly expressed in lung squamous cell carcinomas (SqCC) but not in lung adenocarcinomas. tissue_expression_up hsa-mir-222 "Carcinoma, Hepatocellular" 20103675 overexpression tissue_expression_up hsa-mir-106b Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_up hsa-mir-135b Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_up hsa-mir-18a Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_up hsa-mir-18b Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_up hsa-mir-196b Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_up hsa-mir-19a Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_up hsa-mir-20a Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_up hsa-mir-224 Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_up hsa-mir-301b Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_up hsa-mir-335 Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_up hsa-mir-374a Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_up hsa-mir-424 Colon Neoplasms 20132431 "A total of 14 miRNAs were found to be associated with colonic cancer, in which the expression of miR-106b, miR-135b, miR-18a, miR-18b, miR-196b, miR-19a, miR-224, miR-335, miR-424, miR-20a*, miR-301b and miR-374a were up-regulated and the expression of miR-378 and miR-378* were downregulated in colonic cancer tissues, compared with the para-cancerous control." tissue_expression_up hsa-let-7i Neoplasms [unspecific] 20145181 overexpression tissue_expression_up hsa-let-7i "Squamous Cell Carcinoma, Head and Neck" 20145181 overexpression tissue_expression_up hsa-mir-106b Neoplasms [unspecific] 20145181 Upregulation tissue_expression_up hsa-mir-106b "Squamous Cell Carcinoma, Head and Neck" 20145181 Upregulation tissue_expression_up hsa-mir-142 Neoplasms [unspecific] 20145181 overexpression tissue_expression_up hsa-mir-142 "Squamous Cell Carcinoma, Head and Neck" 20145181 miR-142-3p; overexpression tissue_expression_up hsa-mir-155 Neoplasms [unspecific] 20145181 overexpression tissue_expression_up hsa-mir-155 "Squamous Cell Carcinoma, Head and Neck" 20145181 overexpression tissue_expression_up hsa-mir-16-1 Neoplasms [unspecific] 20145181 Upregulation tissue_expression_up hsa-mir-16-2 Neoplasms [unspecific] 20145181 Upregulation tissue_expression_up hsa-mir-20a Neoplasms [unspecific] 20145181 Upregulation tissue_expression_up hsa-mir-20a "Squamous Cell Carcinoma, Head and Neck" 20145181 Upregulation tissue_expression_up hsa-mir-21 Neoplasms [unspecific] 20145181 overexpression tissue_expression_up hsa-mir-21 "Squamous Cell Carcinoma, Head and Neck" 20145181 overexpression tissue_expression_up hsa-mir-423 Neoplasms [unspecific] 20145181 Upregulation tissue_expression_up hsa-mir-423 "Squamous Cell Carcinoma, Head and Neck" 20145181 Upregulation tissue_expression_up hsa-mir-142 Neoplasms [unspecific] 20178649 "Most of the differentially expressed miRNAs were downregulated in germinomas, but miR-142-5p and miR-146a were upregulated." tissue_expression_up hsa-mir-146a Neoplasms [unspecific] 20178649 "Most of the differentially expressed miRNAs were downregulated in germinomas, but miR-142-5p and miR-146a were upregulated." tissue_expression_up hsa-mir-451 Polycythemia Vera 20218812 We observed that miR-451 up-regulation and miR-150 down-regulation are associated with progression of erythroid maturation in K562 cells. tissue_expression_up hsa-mir-21 Astrocytoma 20219352 "miR-21:hsa-miR-21, hsa-miR-181b and hsa-miR-106a as prognostic indicators of astrocytoma" tissue_expression_up hsa-mir-182 "Leukemia, Biphenotypic, Acute" 20227111 miR-182:miR-584 and miR-182 upregulation in the CD34(+)CD38(-) fraction tissue_expression_up hsa-mir-584 "Leukemia, Biphenotypic, Acute" 20227111 miR-584:miR-584 and miR-182 upregulation in the CD34(+)CD38(-) fraction tissue_expression_up hsa-mir-136 Lung Neoplasms 20237410 "We found that miR-136, miR-376a, and miR-31 were each prominently overexpressed in murine lung cancers." tissue_expression_up hsa-mir-31 Lung Neoplasms 20237410 "We found that miR-136, miR-376a, and miR-31 were each prominently overexpressed in murine lung cancers." tissue_expression_up hsa-mir-376a-1 Lung Neoplasms 20237410 "We found that miR-136, miR-376a, and miR-31 were each prominently overexpressed in murine lung cancers." tissue_expression_up hsa-mir-376a-2 Lung Neoplasms 20237410 "We found that miR-136, miR-376a, and miR-31 were each prominently overexpressed in murine lung cancers." tissue_expression_up hsa-mir-17 Neoplasms [unspecific] 20299512 "The miR-17-92 cluster (encoding miR-17, -18a, -19a/b, -20a, and miR-92a) is highly expressed in tumor cells and is up-regulated by ischemia." tissue_expression_up hsa-mir-18a Neoplasms [unspecific] 20299512 "The miR-17-92 cluster (encoding miR-17, -18a, -19a/b, -20a, and miR-92a) is highly expressed in tumor cells and is up-regulated by ischemia." tissue_expression_up hsa-mir-19a Neoplasms [unspecific] 20299512 "The miR-17-92 cluster (encoding miR-17, -18a, -19a/b, -20a, and miR-92a) is highly expressed in tumor cells and is up-regulated by ischemia." tissue_expression_up hsa-mir-19b-1 Neoplasms [unspecific] 20299512 "The miR-17-92 cluster (encoding miR-17, -18a, -19a/b, -20a, and miR-92a) is highly expressed in tumor cells and is up-regulated by ischemia." tissue_expression_up hsa-mir-20a Neoplasms [unspecific] 20299512 "The miR-17-92 cluster (encoding miR-17, -18a, -19a/b, -20a, and miR-92a) is highly expressed in tumor cells and is up-regulated by ischemia." tissue_expression_up hsa-mir-92a-1 Neoplasms [unspecific] 20299512 "The miR-17-92 cluster (encoding miR-17, -18a, -19a/b, -20a, and miR-92a) is highly expressed in tumor cells and is up-regulated by ischemia." tissue_expression_up hsa-mir-143 "Adenocarcinoma, Esophageal" 20301167 upregulated tissue_expression_up hsa-mir-145 "Adenocarcinoma, Esophageal" 20301167 upregulated tissue_expression_up hsa-mir-203 "Adenocarcinoma, Esophageal" 20301167 miR-203:Levels of miR-203 and miR-205 were high in normal squamous epithelium and low in columnar epithelia tissue_expression_up hsa-mir-205 "Adenocarcinoma, Esophageal" 20301167 miR-205:Levels of miR-203 and miR-205 were high in normal squamous epithelium and low in columnar epithelia tissue_expression_up hsa-mir-21 "Adenocarcinoma, Esophageal" 20301167 upregulated tissue_expression_up hsa-mir-215 "Adenocarcinoma, Esophageal" 20301167 upregulated tissue_expression_up hsa-mir-183 Breast Neoplasms 20331864 up-regulated in male breast cancer tissue_expression_up hsa-mir-197 Breast Neoplasms 20331864 up-regulated in male breast cancer tissue_expression_up hsa-mir-21 Breast Neoplasms 20331864 up-regulated in male breast cancer tissue_expression_up hsa-mir-493 Breast Neoplasms 20331864 up-regulated in male breast cancer tissue_expression_up hsa-mir-519d Breast Neoplasms 20331864 up-regulated in male breast cancer tissue_expression_up hsa-mir-302a Neoplasms [unspecific] 20332240 overexpressed tissue_expression_up hsa-mir-302b Neoplasms [unspecific] 20332240 overexpressed tissue_expression_up hsa-mir-302c Neoplasms [unspecific] 20332240 overexpressed tissue_expression_up hsa-mir-302d Neoplasms [unspecific] 20332240 overexpressed tissue_expression_up hsa-mir-302e Neoplasms [unspecific] 20332240 overexpressed tissue_expression_up hsa-mir-302f Neoplasms [unspecific] 20332240 overexpressed tissue_expression_up hsa-mir-371a Neoplasms [unspecific] 20332240 overexpressed tissue_expression_up hsa-mir-372 Neoplasms [unspecific] 20332240 overexpressed tissue_expression_up hsa-mir-373 Neoplasms [unspecific] 20332240 overexpressed tissue_expression_up hsa-mir-193b Melanoma 20357817 "Furthermore, low expression of miR-191 and high expression of miR-193b were associated with poor melanoma-specific survive" tissue_expression_up hsa-mir-21 Lung Neoplasms 20363096 "upregulated; Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis" tissue_expression_up hsa-let-7a-1 Neoplasms [unspecific] 20370992 over-expressed tissue_expression_up hsa-let-7a-2 Neoplasms [unspecific] 20370992 over-expressed tissue_expression_up hsa-let-7a-3 Neoplasms [unspecific] 20370992 over-expressed tissue_expression_up hsa-mir-182 Neoplasms [unspecific] 20370992 over-expressed tissue_expression_up hsa-mir-21 Neoplasms [unspecific] 20370992 over-expressed tissue_expression_up hsa-mir-21 Gastric Neoplasms 20372781 Expression of miR-21 in cancer tissues was significantly higher than in non-cancer tissues tissue_expression_up hsa-mir-142 Glioblastoma 20380575 "miR-142-3p:The miR-17-3p, miR-17-5p, miR-19a, miR-19b, miR-142-3p, and miR-142-5p were upregulated in both M059K and M059J cells." tissue_expression_up hsa-mir-143 Glioblastoma 20380575 "miR-143:The miR-15a, miR-16, miR-143, miR-155, and miR-21 were upregulated in M059K" tissue_expression_up hsa-mir-155 Glioblastoma 20380575 "miR-155:The miR-15a, miR-16, miR-143, miR-155, and miR-21 were upregulated in M059K" tissue_expression_up hsa-mir-15a Glioblastoma 20380575 "miR-15a:The miR-15a, miR-16, miR-143, miR-155, and miR-21 were upregulated in M059K" tissue_expression_up hsa-mir-16-1 Glioblastoma 20380575 "miR-16:The miR-15a, miR-16, miR-143, miR-155, and miR-21 were upregulated in M059K" tissue_expression_up hsa-mir-16-2 Glioblastoma 20380575 "miR-16:The miR-15a, miR-16, miR-143, miR-155, and miR-21 were upregulated in M059K" tissue_expression_up hsa-mir-17 Glioblastoma 20380575 "miR-17-3p:The miR-17-3p, miR-17-5p, miR-19a, miR-19b, miR-142-3p, and miR-142-5p were upregulated in both M059K and M059J cells." tissue_expression_up hsa-mir-19a Glioblastoma 20380575 "miR-19a:The miR-17-3p, miR-17-5p, miR-19a, miR-19b, miR-142-3p, and miR-142-5p were upregulated in both M059K and M059J cells." tissue_expression_up hsa-mir-19b-1 Glioblastoma 20380575 "miR-19b:The miR-17-3p, miR-17-5p, miR-19a, miR-19b, miR-142-3p, and miR-142-5p were upregulated in both M059K and M059J cells." tissue_expression_up hsa-mir-19b-2 Glioblastoma 20380575 "miR-19b:The miR-17-3p, miR-17-5p, miR-19a, miR-19b, miR-142-3p, and miR-142-5p were upregulated in both M059K and M059J cells." tissue_expression_up hsa-mir-21 Glioblastoma 20380575 "miR-21:The miR-15a, miR-16, miR-143, miR-155, and miR-21 were upregulated in M059K" tissue_expression_up hsa-mir-155 Breast Neoplasms 20388420 "The expression of miR-155 is up-regulated in primary breast cancer, especially in patients with positive estrogen and progesterone receptor." tissue_expression_up hsa-mir-106a Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-106b Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-17 Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-182 Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-183 Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-18a Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-18b Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-20a Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-20b Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-302a Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-302b Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-302c Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-302d Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-367 Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-371a Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-373 Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-93 Glioma 20406893 "miR17 family, mir183-182, and the SC-specific clusters mir367-302 and mir371-373,which are upregulated in gliomas," tissue_expression_up hsa-mir-133a-2 Colorectal Adenocarcinoma 20413677 "miR-133b:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-135a-1 Colorectal Adenocarcinoma 20413677 "miR-135a:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-135a-2 Colorectal Adenocarcinoma 20413677 "miR-135a:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-17 Colorectal Adenocarcinoma 20413677 "miR-17:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-183 Colorectal Adenocarcinoma 20413677 "miR-183:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-203 Colorectal Adenocarcinoma 20413677 "miR-203:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-20a Colorectal Adenocarcinoma 20413677 "miR-20:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-223 Colorectal Adenocarcinoma 20413677 "miR-223:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-25 Colorectal Adenocarcinoma 20413677 "miR-25:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-31 Colorectal Adenocarcinoma 20413677 "miR-31:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-92a-1 Colorectal Adenocarcinoma 20413677 "miR-92:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-92a-2 Colorectal Adenocarcinoma 20413677 "miR-92:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-93 Colorectal Adenocarcinoma 20413677 "miR-93:eleven miRNAs (miR-183, -31, -20, -25, -92, -93, -17, -135a, -203,-133b, and -223) were over-expressed in CRC relative to mucosa," tissue_expression_up hsa-mir-126 Lung Neoplasms 20418022 "This set includes hsa-miR-182, which was most strongly over-expressed in the lung primary tumors, and hsa-miR-126, which was over-expressed in the metastatic tumors." tissue_expression_up hsa-mir-182 Lung Neoplasms 20418022 "This set includes hsa-miR-182, which was most strongly over-expressed in the lung primary tumors, and hsa-miR-126, which was over-expressed in the metastatic tumors." tissue_expression_up hsa-mir-372 Liver Neoplasms 20423907 "microRNA-372:CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer" tissue_expression_up hsa-mir-106a Toxoplasma gondii Infection 20423977 hsa-mir-106a:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii tissue_expression_up hsa-mir-106b Toxoplasma gondii Infection 20423977 hsa-mir-106b:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii tissue_expression_up hsa-mir-17 Toxoplasma gondii Infection 20423977 hsa-mir-17:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii tissue_expression_up hsa-mir-18a Toxoplasma gondii Infection 20423977 hsa-mir-18a:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii tissue_expression_up hsa-mir-18b Toxoplasma gondii Infection 20423977 hsa-mir-18b:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii tissue_expression_up hsa-mir-20a Toxoplasma gondii Infection 20423977 hsa-mir-20a:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii tissue_expression_up hsa-mir-20b Toxoplasma gondii Infection 20423977 hsa-mir-20b:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii tissue_expression_up hsa-mir-93 Toxoplasma gondii Infection 20423977 hsa-mir-93:human miR-17 family members that are increased by infection with the intracellular parasite Toxoplasma gondii tissue_expression_up hsa-mir-221 Glioblastoma 20428775 miR-221:STAT1/2 upregulation under the transcriptional control of INF-alpha signaling after knockdown of miR-221/222 cluster in U251 glioma cells tissue_expression_up hsa-mir-222 Glioblastoma 20428775 miR-222:STAT1/2 upregulation under the transcriptional control of INF-alpha signaling after knockdown of miR-221/222 cluster in U251 glioma cells tissue_expression_up hsa-mir-205 "Squamous Cell Carcinoma, Esophageal" 20428818 miR-205:miR-205 and miR-21 are specific markers for HNSCC and ESCC tissue_expression_up hsa-mir-205 "Squamous Cell Carcinoma, Head and Neck" 20428818 miR-205:miR-205 and miR-21 are specific markers for HNSCC and ESCC tissue_expression_up hsa-mir-21 "Squamous Cell Carcinoma, Esophageal" 20428818 miR-21:miR-205 and miR-21 are specific markers for HNSCC and ESCC tissue_expression_up hsa-mir-21 "Squamous Cell Carcinoma, Head and Neck" 20428818 miR-21:miR-205 and miR-21 are specific markers for HNSCC and ESCC tissue_expression_up hsa-mir-146a Melanoma 20442294 miR-146a:miR-146a and miR-155 were upregulated in all analyzed patients but none of the cell lines tissue_expression_up hsa-mir-155 Melanoma 20442294 miR-155:miR-146a and miR-155 were upregulated in all analyzed patients but none of the cell lines tissue_expression_up hsa-mir-208 "Cardiomyopathy, Dilated" 20447577 "Levels of miR-208, miR-208b, and miR-499 were higher in DCM patients than in controls." tissue_expression_up hsa-mir-208b "Cardiomyopathy, Dilated" 20447577 "Levels of miR-208, miR-208b, and miR-499 were higher in DCM patients than in controls." tissue_expression_up hsa-mir-499 "Cardiomyopathy, Dilated" 20447577 "Levels of miR-208, miR-208b, and miR-499 were higher in DCM patients than in controls." tissue_expression_up hsa-mir-1-1 Rhabdomyosarcoma 20466878 miR-1:mRNA targets of miR-1 and miR-133a are up-regulated in rhabdomyosarcomas tissue_expression_up hsa-mir-1-2 Rhabdomyosarcoma 20466878 miR-1:mRNA targets of miR-1 and miR-133a are up-regulated in rhabdomyosarcomas tissue_expression_up hsa-mir-133a-1 Rhabdomyosarcoma 20466878 miR-133a:mRNA targets of miR-1 and miR-133a are up-regulated in rhabdomyosarcomas tissue_expression_up hsa-mir-296 "Squamous Cell Carcinoma, Esophageal" 20485139 miR-296:MiR-296 might play important roles in the pathogenesis of esophageal cancer and considered as a potential target for this malignancy intervention tissue_expression_up hsa-mir-206 Myotonic Muscular Dystrophy 20487562 microRNA-206:Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients tissue_expression_up hsa-mir-18a Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_up hsa-mir-21 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_up hsa-mir-22 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_up hsa-mir-31 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_up hsa-mir-34a Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_up hsa-mir-412 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_up hsa-mir-504 Lung Neoplasms 20508945 "Seven miRNAs of hsa-miR-21, hsa-miR-31, hsa-miR-34a, hsa-miR-22*, hsa-miR-504, hsa-miR-18a, and hsa-miR-412 were observed to be upregulated greater than twofold in the squamous cell lung carcinoma tissues compared with normal tissues, whereas 23 miRNAs of hsa-miR-30a, hsa-miR-30d, hsa-miR-126, hsa-miR-652, hsa-miR-100, hsa-miR-143, hsa-miR-130a, hsa-miR-145, hsa-miR-30e, hsa-miR-126*, hsa-miR-181a, hsa-miR-125b, hsa-miR-886-3p, hsa-miR-451, hsa-miR-29c, hsa-miR-26b, hsa-miR-101, hsa-miR-320, hsa-miR-30b, hsa-miR-886-5p, hsa-miR-29a, hsa-miR-26a, and hsa-miR-99a were found to be downregulated greater than twofold." tissue_expression_up hsa-mir-106a Colon Neoplasms 20551304 miRNA expression profiles from 29 patients showed higher expression of miR-21 and miR-106a in patients with adenomas and CRCs compared with individuals free of colorectal neoplasia. tissue_expression_up hsa-mir-21 "Carcinoma, Rectal" 20551304 miRNA expression profiles from 29 patients showed higher expression of miR-21 and miR-106a in patients with adenomas and CRCs compared with individuals free of colorectal neoplasia. tissue_expression_up hsa-mir-155 "Colitis, Ulcerative" 20586854 miR-155:Upregulated miRNA may be responsible for the development of intestinal inflammation in UC tissue_expression_up hsa-mir-21 "Colitis, Ulcerative" 20586854 miR-21:Upregulated miRNA may be responsible for the development of intestinal inflammation in UC tissue_expression_up hsa-mir-183 "Carcinoma, Hepatocellular" 20602797 "Among the 25 HCC samples analyzed, microRNA-183 was significantly up-regulated (twofold to 367-fold) in 17 samples compared with the matching nontumoral liver tissues." tissue_expression_up hsa-mir-103a-1 Breast Neoplasms 20603000 "miR-103:In human breast cancer, high levels of miR-103/107 are associated with metastasis and poor outcome" tissue_expression_up hsa-mir-103a-2 Breast Neoplasms 20603000 "miR-103:In human breast cancer, high levels of miR-103/107 are associated with metastasis and poor outcome" tissue_expression_up hsa-mir-107 Breast Neoplasms 20603000 "miR-107:In human breast cancer, high levels of miR-103/107 are associated with metastasis and poor outcome" tissue_expression_up hsa-mir-126 "Carcinoma, Hepatocellular" 20619223 miR-126:hsa-miR-126 showed higher expression levels in hepatocellular carcinomas tissue_expression_up hsa-mir-125a "Squamous Cell Carcinoma, Lung" 20620595 miR-125a-5p:The miRNAs miR-185 * and miR-125a-5p were significantly upregulated in lung SCC tissue_expression_up hsa-mir-185 "Squamous Cell Carcinoma, Lung" 20620595 miR-185:The miRNAs miR-185 * and miR-125a-5p were significantly upregulated in lung SCC tissue_expression_up hsa-mir-103a-1 Lung Neoplasms 20624269 "miR-103:we found significant overexpression of miR-103, miR-107, miR-301 and miR-338 in lung cancer cells as compared to HBECs" tissue_expression_up hsa-mir-103a-2 Lung Neoplasms 20624269 "miR-103:we found significant overexpression of miR-103, miR-107, miR-301 and miR-338 in lung cancer cells as compared to HBECs" tissue_expression_up hsa-mir-107 Lung Neoplasms 20624269 "miR-107:we found significant overexpression of miR-103, miR-107, miR-301 and miR-338 in lung cancer cells as compared to HBECs" tissue_expression_up hsa-mir-301a Lung Neoplasms 20624269 "miR-301:we found significant overexpression of miR-103, miR-107, miR-301 and miR-338 in lung cancer cells as compared to HBECs" tissue_expression_up hsa-mir-338 Lung Neoplasms 20624269 "miR-338:we found significant overexpression of miR-103, miR-107, miR-301 and miR-338 in lung cancer cells as compared to HBECs" tissue_expression_up hsa-mir-1-1 Myelodysplastic Syndromes 20627384 miR-1:Evaluation in a larger cohort could confirm the up-regulation of the miR-1 in MDS tissue_expression_up hsa-mir-1-2 Myelodysplastic Syndromes 20627384 miR-1:Evaluation in a larger cohort could confirm the up-regulation of the miR-1 in MDS tissue_expression_up hsa-mir-1246 Adenovirus Infection 20634878 miR-1246:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-1247 Adenovirus Infection 20634878 miR-1247:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-1273a Adenovirus Infection 20634878 miR-1273:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-1302-1 Adenovirus Infection 20634878 miR-1302-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-1302-2 Adenovirus Infection 20634878 miR-1302-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-1302-3 Adenovirus Infection 20634878 miR-1302-3:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-1302-4 Adenovirus Infection 20634878 miR-1302-4:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-1302-5 Adenovirus Infection 20634878 miR-1302-5:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-1302-6 Adenovirus Infection 20634878 miR-1302-6:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-1302-7 Adenovirus Infection 20634878 miR-1302-7:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-1302-8 Adenovirus Infection 20634878 miR-1302-8:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-146b Adenovirus Infection 20634878 miR-146b:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-150 Adenovirus Infection 20634878 miR-150:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-17 Adenovirus Infection 20634878 miR-17:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-18a Adenovirus Infection 20634878 miR-18a:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-191 Adenovirus Infection 20634878 miR-191:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-1972-1 Adenovirus Infection 20634878 miR-1972:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-320c-2 Adenovirus Infection 20634878 miR-320c-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-324 Adenovirus Infection 20634878 miR-324:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-342 Adenovirus Infection 20634878 miR-342:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-345 Adenovirus Infection 20634878 miR-345:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-378a Adenovirus Infection 20634878 miR-378:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-454 Adenovirus Infection 20634878 miR-454:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-505 Adenovirus Infection 20634878 miR-505:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-566 Adenovirus Infection 20634878 miR-566:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-589 Adenovirus Infection 20634878 miR-589:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-627 Adenovirus Infection 20634878 miR-627:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-635 Adenovirus Infection 20634878 miR-635:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-7-1 Adenovirus Infection 20634878 miR-7-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-7-2 Adenovirus Infection 20634878 miR-7-2:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-7-3 Adenovirus Infection 20634878 miR-7-3:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-744 Adenovirus Infection 20634878 miR-744:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-92a-1 Adenovirus Infection 20634878 miR-92a-1:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-942 Adenovirus Infection 20634878 miR-942:A total of 44 miRNAs demonstrated high expression and 36 miRNAs showed lower expression in the AD3 infected cells than control tissue_expression_up hsa-mir-33 Squamous Cell Carcinoma 20652977 "The miRNAs miR-363, miR-33, and miR-497 were upregulated, whereas miR-155, miR-181a, miR-181b, miR-29a, miR-218, miR-222, miR-221, and miR-142-5p were downregulated in HPV-positive cells compared to both HPV-negative SCCHN and normal oral keratinocytes." tissue_expression_up hsa-mir-363 Squamous Cell Carcinoma 20652977 "The miRNAs miR-363, miR-33, and miR-497 were upregulated, whereas miR-155, miR-181a, miR-181b, miR-29a, miR-218, miR-222, miR-221, and miR-142-5p were downregulated in HPV-positive cells compared to both HPV-negative SCCHN and normal oral keratinocytes." tissue_expression_up hsa-mir-497 Squamous Cell Carcinoma 20652977 "The miRNAs miR-363, miR-33, and miR-497 were upregulated, whereas miR-155, miR-181a, miR-181b, miR-29a, miR-218, miR-222, miR-221, and miR-142-5p were downregulated in HPV-positive cells compared to both HPV-negative SCCHN and normal oral keratinocytes." tissue_expression_up hsa-mir-17 Pancreatic Neoplasms 20703102 "MicroRNA miR-17-5p is overexpressed in pancreatic cancer, associated with a poor prognosis, and involved in cancer cell proliferation and invasion" tissue_expression_up hsa-mir-21 Astrocytoma 20711171 Inhibition of two glioblastoma-upregulated miRNAs (miR-21 and miR-23a) and exogenous overexpression of two glioblastoma-downregulated miRNAs (miR-218 and miR-219-5p) resulted in reduced soft agar colony formation but showed varying effects on cell proliferation and chemosensitivity. tissue_expression_up hsa-mir-23a Astrocytoma 20711171 Inhibition of two glioblastoma-upregulated miRNAs (miR-21 and miR-23a) and exogenous overexpression of two glioblastoma-downregulated miRNAs (miR-218 and miR-219-5p) resulted in reduced soft agar colony formation but showed varying effects on cell proliferation and chemosensitivity. tissue_expression_up hsa-let-7f Ovarian Neoplasms 20716115 "Reduced miR-145 and miR-214 and elevated let-7f, miR-182, miR-210, miR-200c, miR-222 and miR-23a levels were found in effusions in both sets." tissue_expression_up hsa-mir-182 Ovarian Neoplasms 20716115 "Reduced miR-145 and miR-214 and elevated let-7f, miR-182, miR-210, miR-200c, miR-222 and miR-23a levels were found in effusions in both sets." tissue_expression_up hsa-mir-200c Ovarian Neoplasms 20716115 "Reduced miR-145 and miR-214 and elevated let-7f, miR-182, miR-210, miR-200c, miR-222 and miR-23a levels were found in effusions in both sets." tissue_expression_up hsa-mir-210 Ovarian Neoplasms 20716115 "Reduced miR-145 and miR-214 and elevated let-7f, miR-182, miR-210, miR-200c, miR-222 and miR-23a levels were found in effusions in both sets." tissue_expression_up hsa-mir-222 Ovarian Neoplasms 20716115 "Reduced miR-145 and miR-214 and elevated let-7f, miR-182, miR-210, miR-200c, miR-222 and miR-23a levels were found in effusions in both sets." tissue_expression_up hsa-mir-23a Ovarian Neoplasms 20716115 "Reduced miR-145 and miR-214 and elevated let-7f, miR-182, miR-210, miR-200c, miR-222 and miR-23a levels were found in effusions in both sets." tissue_expression_up hsa-mir-106a Breast Neoplasms 20801493 "A high correlation of miRNA expression level was found between breast tumor tissues and sera. MiR-21, miR-106a and miR-155 were significantly over-expressed in the tumor specimens compared with those in normal controls (P < 0.05), whereas miR-126, miR-199a and miR-335 were significantly under-expressed (P < 0.05)." tissue_expression_up hsa-mir-155 Breast Neoplasms 20801493 "A high correlation of miRNA expression level was found between breast tumor tissues and sera. MiR-21, miR-106a and miR-155 were significantly over-expressed in the tumor specimens compared with those in normal controls (P < 0.05), whereas miR-126, miR-199a and miR-335 were significantly under-expressed (P < 0.05)." tissue_expression_up hsa-mir-21 Breast Neoplasms 20801493 "A high correlation of miRNA expression level was found between breast tumor tissues and sera. MiR-21, miR-106a and miR-155 were significantly over-expressed in the tumor specimens compared with those in normal controls (P < 0.05), whereas miR-126, miR-199a and miR-335 were significantly under-expressed (P < 0.05)." tissue_expression_up hsa-mir-223 Gastrointestinal Neoplasms 20802470 "Taken together, aberrant E2A expression is a diagnostic feature of a subtype of gastric MALT lymphoma with weaker plasmacytoid infiltrates and stronger miR-223 expression." tissue_expression_up hsa-mir-20b Laryngeal Neoplasms 20806854 upregulated by 3 multiple tissue_expression_up hsa-mir-31 Laryngeal Neoplasms 20806854 upregulated by 3 multiple tissue_expression_up hsa-mir-93 Laryngeal Neoplasms 20806854 upregulated by 3 multiple tissue_expression_up hsa-let-7a-1 Spinal Cord Injuries 20816819 Let-7a:SCI results in increased expression of miR Let-7a and miR16 tissue_expression_up hsa-let-7a-2 Spinal Cord Injuries 20816819 Let-7a:SCI results in increased expression of miR Let-7a and miR16 tissue_expression_up hsa-let-7a-3 Spinal Cord Injuries 20816819 Let-7a:SCI results in increased expression of miR Let-7a and miR16 tissue_expression_up hsa-mir-15b Spinal Cord Injuries 20816819 "spinal cord injury (SCI)results in increased expression of miR Let-7a and miR16 while exercise leads to elevated levels of miR21 and decreased levels of miR15b. These changes in miR expression are correlated with changes in expression of their target genes: pro-apoptotic (decreased PTEN, PDCD4, and RAS mRNA) and anti-apoptotic (increased Bcl-2 mRNA) target genes. This is accompanied by a down-regulation of mRNA for caspase-7 and caspase-9 and reduced levels of caspase-7 protein." tissue_expression_up hsa-mir-16-1 Spinal Cord Injuries 20816819 miR16:SCI results in increased expression of miR Let-7a and miR16 tissue_expression_up hsa-mir-16-2 Spinal Cord Injuries 20816819 miR16:SCI results in increased expression of miR Let-7a and miR16 tissue_expression_up hsa-mir-192 Neoplasms [unspecific] 20864637 "miR-192:Hsa-miR-193-3p was overexpressed in MPM, while hsa-miR-200c and hsa-miR-192 were overexpressed in peripheral lung adenocarcinoma and carcinomas" tissue_expression_up hsa-mir-193a Mesothelioma 20864637 "miR-193-3p:Hsa-miR-193-3p was overexpressed in MPM, while hsa-miR-200c and hsa-miR-192 were overexpressed in peripheral lung adenocarcinoma and carcinomas" tissue_expression_up hsa-mir-200c "Adenocarcinoma, Lung" 20864637 "miR-200c:Hsa-miR-193-3p was overexpressed in MPM, while hsa-miR-200c and hsa-miR-192 were overexpressed in peripheral lung adenocarcinoma and carcinomas" tissue_expression_up hsa-mir-200a "Fatty Liver, Non-Alcoholic" 20956972 "The miRNAs analysis showed the significant downregulation of three miRNAs (miR-122, miR-451 and miR-27) and the upregulation of miR-200a, miR-200b and miR-429 in HFD, SD-HF and HFD-HF rats" tissue_expression_up hsa-mir-200b "Fatty Liver, Non-Alcoholic" 20956972 "The miRNAs analysis showed the significant downregulation of three miRNAs (miR-122, miR-451 and miR-27) and the upregulation of miR-200a, miR-200b and miR-429 in HFD, SD-HF and HFD-HF rats" tissue_expression_up hsa-mir-429 "Fatty Liver, Non-Alcoholic" 20956972 "The miRNAs analysis showed the significant downregulation of three miRNAs (miR-122, miR-451 and miR-27) and the upregulation of miR-200a, miR-200b and miR-429 in HFD, SD-HF and HFD-HF rats" tissue_expression_up hsa-mir-195 Astrocytoma 20976148 The observation that miR-34a and miR-195 levels were increased in the RISC of U-87 astrocytoma cells suggests an oncogenic role for these miRNAs. tissue_expression_up hsa-mir-34a Astrocytoma 20976148 The observation that miR-34a and miR-195 levels were increased in the RISC of U-87 astrocytoma cells suggests an oncogenic role for these miRNAs. tissue_expression_up hsa-mir-141 "Carcinoma, Endometrioid Endometrial" 21035172 "A miRNA microarray showed that the miR-200 family, including hsa-miR-141, hsa-miR-200a, hsa-miR-200b, hsa-miR-200c, and hsa-miR-429, was up-regulated in EECs as compared with that in normal endometrial tissues." tissue_expression_up hsa-mir-200a "Carcinoma, Endometrioid Endometrial" 21035172 "A miRNA microarray showed that the miR-200 family, including hsa-miR-141, hsa-miR-200a, hsa-miR-200b, hsa-miR-200c, and hsa-miR-429, was up-regulated in EECs as compared with that in normal endometrial tissues." tissue_expression_up hsa-mir-200b "Carcinoma, Endometrioid Endometrial" 21035172 "A miRNA microarray showed that the miR-200 family, including hsa-miR-141, hsa-miR-200a, hsa-miR-200b, hsa-miR-200c, and hsa-miR-429, was up-regulated in EECs as compared with that in normal endometrial tissues." tissue_expression_up hsa-mir-200c "Carcinoma, Endometrioid Endometrial" 21035172 "A miRNA microarray showed that the miR-200 family, including hsa-miR-141, hsa-miR-200a, hsa-miR-200b, hsa-miR-200c, and hsa-miR-429, was up-regulated in EECs as compared with that in normal endometrial tissues." tissue_expression_up hsa-mir-429 "Carcinoma, Endometrioid Endometrial" 21035172 "These results indicate that the miR-200 family is highly expressed in EECs compared with that of normal endometrial tissues and could play an important role in cancer growth. Specifically, anti-miR-429 could enhance the cytotoxic activity with cisplatin in EECs." tissue_expression_up hsa-mir-196a "Niemann-Pick Disease, Type C" 21075073 "We found that three miRNAs, miR-196a, miR-196b and miR-296 were up-regulated (>3.5-fold increase, p<0.05) whereas 38 miRNAs were significantly down-regulated in NPC cells (>3.5-fold decrease, p<0.05)." tissue_expression_up hsa-mir-196b "Niemann-Pick Disease, Type C" 21075073 "We found that three miRNAs, miR-196a, miR-196b and miR-296 were up-regulated (>3.5-fold increase, p<0.05) whereas 38 miRNAs were significantly down-regulated in NPC cells (>3.5-fold decrease, p<0.05)." tissue_expression_up hsa-mir-296 "Niemann-Pick Disease, Type C" 21075073 "We found that three miRNAs, miR-196a, miR-196b and miR-296 were up-regulated (>3.5-fold increase, p<0.05) whereas 38 miRNAs were significantly down-regulated in NPC cells (>3.5-fold decrease, p<0.05)." tissue_expression_up hsa-mir-192 Gastric Neoplasms 21119604 MicroRNA-192 and -215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro. tissue_expression_up hsa-mir-215 Gastric Neoplasms 21119604 MicroRNA-192 and -215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro. tissue_expression_up hsa-mir-155 "Carcinoma, Endometrial" 21125666 "Up-regulated miRNAs included miR-155, miR-369-5p, miR-370, miR-450a and miR-542-5p. These data suggest that in human ECS, the interplay between transcriptional repressors of E-cadherin and miRNAs provides a link between EMT-activation and the maintenance of stemness." tissue_expression_up hsa-mir-369 "Carcinoma, Endometrial" 21125666 "Up-regulated miRNAs included miR-155, miR-369-5p, miR-370, miR-450a and miR-542-5p. These data suggest that in human ECS, the interplay between transcriptional repressors of E-cadherin and miRNAs provides a link between EMT-activation and the maintenance of stemness." tissue_expression_up hsa-mir-450a "Carcinoma, Endometrial" 21125666 "Up-regulated miRNAs included miR-155, miR-369-5p, miR-370, miR-450a and miR-542-5p. These data suggest that in human ECS, the interplay between transcriptional repressors of E-cadherin and miRNAs provides a link between EMT-activation and the maintenance of stemness." tissue_expression_up hsa-mir-542 "Carcinoma, Endometrial" 21125666 "Up-regulated miRNAs included miR-155, miR-369-5p, miR-370, miR-450a and miR-542-5p. These data suggest that in human ECS, the interplay between transcriptional repressors of E-cadherin and miRNAs provides a link between EMT-activation and the maintenance of stemness." tissue_expression_up hsa-mir-34a Myelodysplastic Syndromes 21150891 "In early MDS, we monitored upregulation of proapoptotic miR-34a" tissue_expression_up hsa-mir-7-1 Neurilemmoma 21156648 miRNA-7 attenuation in schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways. tissue_expression_up hsa-mir-7-2 Neurilemmoma 21156648 miRNA-7 attenuation in schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways. tissue_expression_up hsa-mir-7-3 Neurilemmoma 21156648 miRNA-7 attenuation in schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways. tissue_expression_up hsa-mir-1-1 Myotonic Muscular Dystrophy 21169019 "We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls." tissue_expression_up hsa-mir-335 Myotonic Muscular Dystrophy 21169019 "We found that miR-1 and miR-335 were up-regulated, whereas miR-29b and c, and miR-33 were down-regulated in DM1 biopsies compared to controls." tissue_expression_up hsa-mir-1179 Colorectal Carcinoma 21174058 "miR-150*, miR-125b-2*, miR-1179 and miR-139-3p were up-regulated in colorectal cancers with liver metastasis" tissue_expression_up hsa-mir-125b-2 Colorectal Carcinoma 21174058 "miR-150*, miR-125b-2*, miR-1179 and miR-139-3p were up-regulated in colorectal cancers with liver metastasis" tissue_expression_up hsa-mir-139 Colorectal Carcinoma 21174058 "miR-150*, miR-125b-2*, miR-1179 and miR-139-3p were up-regulated in colorectal cancers with liver metastasis" tissue_expression_up hsa-mir-150 Colorectal Carcinoma 21174058 "miR-150*, miR-125b-2*, miR-1179 and miR-139-3p were up-regulated in colorectal cancers with liver metastasis" tissue_expression_up hsa-mir-210 Liver Neoplasms 21175813 upregulated after arsenic trioxide treatment in HepG-2 cells tissue_expression_up hsa-mir-24-1 Liver Neoplasms 21175813 upregulated after arsenic trioxide treatment in HepG-2 cells tissue_expression_up hsa-mir-24-2 Liver Neoplasms 21175813 upregulated after arsenic trioxide treatment in HepG-2 cells tissue_expression_up hsa-mir-29a Liver Neoplasms 21175813 "upregulated after arsenic trioxide treatment in HepG-2 cells miR-29a showed a positive therapeutic effect in liver cancer cells by inhibiting cell growth and inducing cell apoptosis, and PPM1D was confirmed to be the target gene of miR-29a." tissue_expression_up hsa-mir-30a Liver Neoplasms 21175813 upregulated after arsenic trioxide treatment in HepG-2 cells tissue_expression_up hsa-mir-10b Liver Neoplasms 21176238 overexpressed in side population of HCC cells compared to fetal liver cells tissue_expression_up hsa-mir-21 Liver Neoplasms 21176238 overexpressed in side population of HCC cells compared to fetal liver cells tissue_expression_up hsa-mir-34c Liver Neoplasms 21176238 miR-34c-3p is overexpressed in side population of HCC cells compared to fetal liver cells tissue_expression_up hsa-mir-183 Ovarian Neoplasms 21176563 "Increased expression of miR-183 and miR-22 may both repress the protein level of ezrin, indicating that miR-183 and miR-22 may bear a potential role in inhibiting ovarian cancer metastasis in a ezrin-mediated way" tissue_expression_up hsa-mir-22 Ovarian Neoplasms 21176563 "Increased expression of miR-183 and miR-22 may both repress the protein level of ezrin, indicating that miR-183 and miR-22 may bear a potential role in inhibiting ovarian cancer metastasis in a ezrin-mediated way" tissue_expression_up hsa-mir-330 Prostate Neoplasms 21177307 "We also observed a significant down-regulation of androgen-regulated miRNA-21 and up-regulation of a tumor suppressor, miRNA-330, in tumors of mice treated with EGCG" tissue_expression_up hsa-let-7e Synovial Sarcoma 21213367 upregulated tissue_expression_up hsa-mir-125a Synovial Sarcoma 21213367 hsa-mir-125a-3p upregulated tissue_expression_up hsa-mir-99b Synovial Sarcoma 21213367 upregulated tissue_expression_up hsa-mir-29b-1 Urinary Bladder Cancer 21223810 "In grade I, grade II, grade III, grade I + II + III, infiltrating and non-infiltrating groups, hsa-miR-29b-1* was up-regulated while hsa-miR-923 and hsa-miR-300 were down-regulated" tissue_expression_up hsa-mir-129-1 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-129-2 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-146b "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-21 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-210 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-212 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-214 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-23a "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-23b "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-25 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-338 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-489 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-515-1 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-515-2 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-92a-1 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-92a-2 "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-mir-92b "Squamous Cell Carcinoma, Oral" 21244772 "Thirteen miRNA were significantly overexpressed (miR-489, miR-129, miR-23a, miR-214, miR-23b, miR-92, miR-25, miR-210, miR-212, miR-515, miR-146b, miR-21, miR-338) and 6 miRNA were underexpressed (miR-520h, miR-197, miR-378, miR-135b, miR-224, miR-34a) in oral tumours. Underexpression of mir-155, let-7i, mir-146a was found to characterize progression to metastastatic tumours." tissue_expression_up hsa-let-7c Prostate Neoplasms 21255804 "Using the Cox regression test the risk of recurrence was 3.0, 3.3, 2.7 and 3.4 for high levels of miR-100, miR-145, miR-191 and miR-let7c, respectively." tissue_expression_up hsa-mir-100 Prostate Neoplasms 21255804 "Using the Cox regression test the risk of recurrence was 3.0, 3.3, 2.7 and 3.4 for high levels of miR-100, miR-145, miR-191 and miR-let7c, respectively." tissue_expression_up hsa-mir-145 Prostate Neoplasms 21255804 "Using the Cox regression test the risk of recurrence was 3.0, 3.3, 2.7 and 3.4 for high levels of miR-100, miR-145, miR-191 and miR-let7c, respectively." tissue_expression_up hsa-mir-191 Prostate Neoplasms 21255804 "Using the Cox regression test the risk of recurrence was 3.0, 3.3, 2.7 and 3.4 for high levels of miR-100, miR-145, miR-191 and miR-let7c, respectively." tissue_expression_up hsa-mir-495 Breast Neoplasms 21258409 "miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1." tissue_expression_up hsa-mir-126 "Carcinoma, Lung, Non-Small-Cell" 21264844 Independent and tissue-specific prognostic impact of miR-126 in nonsmall cell lung cancer: Coexpression with vascular endothelial growth factor-A predicts poor survival. tissue_expression_up hsa-mir-126 Esophageal Neoplasms 21269950 hsa-mir-126 is upregulated and hsa-miR-518b is downregulated in esophageal squamous carcinoma tissue_expression_up hsa-mir-21 Breast Neoplasms 21270527 "miR-21, miR-210 and miR-221 were significantly overexpressed, whereas miR-10b, miR-145, miR-205, miR-122a were significantly underexpressed in the triple-negative primary breast cancers." tissue_expression_up hsa-mir-210 Breast Neoplasms 21270527 "miR-21, miR-210 and miR-221 were significantly overexpressed, whereas miR-10b, miR-145, miR-205, miR-122a were significantly underexpressed in the triple-negative primary breast cancers." tissue_expression_up hsa-mir-221 Breast Neoplasms 21270527 "miR-21, miR-210 and miR-221 were significantly overexpressed, whereas miR-10b, miR-145, miR-205, miR-122a were significantly underexpressed in the triple-negative primary breast cancers." tissue_expression_up hsa-mir-181a-2 Breast Neoplasms 21271219 Increased miR-21 and miR-181a levels were significantly associated with shortened tissue_expression_up hsa-mir-21 Breast Neoplasms 21271219 "Increased miR-21 and miR-181a levels were significantly associated with shortened disease-free survival(DFS; p=0.0003, 0.0007) and overall survival (OS; p=0.0351, 0.0443), respectively. Accumulation of miR-21 and miR-181a in bone marrow appears to be associated with prognosis in breast cancer patients. The much higher significant correlation with microRNA levels and prognosis suggests epistatic effects on multiple target genes in the bone marrow of breast cancer patients." tissue_expression_up hsa-mir-373 Breast Neoplasms 21271679 miR-373 was found to be capable of promoting breast cancer invasion and metastasis tissue_expression_up hsa-mir-221 Thyroid Neoplasms 21275764 mir-221 was overexpressed in 19 patients (p<0.0001) with a sensitive yield of 95%. tissue_expression_up hsa-mir-638 Lung Neoplasms 21303527 We found the upregulation of microRNA-638 and microRNA-923 in bostrycin-treated lung adenocarcinoma cells tissue_expression_up hsa-let-7b Preeclampsia 21309633 "Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b." tissue_expression_up hsa-mir-128-1 Preeclampsia 21309633 "Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b." tissue_expression_up hsa-mir-128-2 Preeclampsia 21309633 "Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b." tissue_expression_up hsa-mir-133b Preeclampsia 21309633 "Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b." tissue_expression_up hsa-mir-182 Preeclampsia 21309633 "Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b." tissue_expression_up hsa-mir-21 Preeclampsia 21309633 "Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b." tissue_expression_up hsa-mir-302a Preeclampsia 21309633 "Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b." tissue_expression_up hsa-mir-302b Preeclampsia 21309633 "Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b." tissue_expression_up hsa-mir-302c Preeclampsia 21309633 "Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b." tissue_expression_up hsa-mir-302d Preeclampsia 21309633 "Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b." tissue_expression_up hsa-mir-302e Preeclampsia 21309633 "Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b." tissue_expression_up hsa-mir-302f Preeclampsia 21309633 "Six miRNAs were more than 2-fold over-expressed in severe preeclampsia: let-7b, miRNA-302*, miRNA-104, miRNA-128a, miRNA-182* and miRNA-133b." tissue_expression_up hsa-mir-17 Mesothelioma 21317924 Hsa-miR-17* was significantly upregulated and hsa-miR-30c was significantly downregulated by Onconase treatment in all cell lines tissue_expression_up hsa-mir-492 Hepatoblastoma 21319197 MicroRNA-492 is processed from the keratin 19 gene and up-regulated in metastatic hepatoblastoma. tissue_expression_up hsa-mir-151a "Carcinoma, Hepatocellular" 21319996 miR-30d and miR-151 were amplified in ~50% of Hepatitis B Virus-Associated HCC tumor tissues tissue_expression_up hsa-mir-30d "Carcinoma, Hepatocellular" 21319996 miR-30d and miR-151 were amplified in ~50% of Hepatitis B Virus-Associated HCC tumor tissues tissue_expression_up hsa-mir-21 Breast Neoplasms 21326627 miR-21 Expression in Pregnancy-Associated Breast Cancer: A Possible Marker of Poor Prognosis. tissue_expression_up hsa-mir-21 Endometrial Neoplasms 21330826 Highly increased maspin expression corresponds with up-regulation of miR-21 in endometrial cancer tissue_expression_up hsa-mir-142 Gastric Neoplasms 21343377 A high frequency recurrence and poor survival were observed in gastric cancer cases with high level of hsa-miR-375 and low level of hsa-miR-142-5p (P < 0.001). The results indicate that the combination of hsa-miR-375 and hsa-miR-142-5p as a predictor of disease progression has the potential to predict recurrence risk for GC patients. tissue_expression_up hsa-mir-142 Gastrointestinal Neoplasms 21343377 "A high frequency recurrence and poor survival were observed in GC cases with high level of hsa-miR-375 and low level of hsa-miR-142-5p (P < 0.001),indicating that the combination of hsa-miR-375 and hsa-miR-142-5p as a predictor of disease progression has the potential to predict recurrence risk for GC patients" tissue_expression_up hsa-mir-375 Gastric Neoplasms 21343377 A high frequency recurrence and poor survival were observed in gastric cancer cases with high level of hsa-miR-375 and low level of hsa-miR-142-5p (P < 0.001). The results indicate that the combination of hsa-miR-375 and hsa-miR-142-5p as a predictor of disease progression has the potential to predict recurrence risk for GC patients. tissue_expression_up hsa-mir-375 Gastrointestinal Neoplasms 21343377 "A high frequency recurrence and poor survival were observed in GC cases with high level of hsa-miR-375 and low level of hsa-miR-142-5p (P < 0.001),indicating that the combination of hsa-miR-375 and hsa-miR-142-5p as a predictor of disease progression has the potential to predict recurrence risk for GC patients" tissue_expression_up hsa-mir-142 Pancreatic Neoplasms 21347785 patients with high miR-142-5p and miR-204 expression had significantly longer survival times than those with low miR-142-5p (P = 0.0077) and miR-204 (P = 0.0054) expression in the gemcitabine-treated group. tissue_expression_up hsa-mir-204 Pancreatic Neoplasms 21347785 patients with high miR-142-5p and miR-204 expression had significantly longer survival times than those with low miR-142-5p (P = 0.0077) and miR-204 (P = 0.0054) expression in the gemcitabine-treated group. tissue_expression_up hsa-mir-106a Mesothelioma 21358347 "miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated" tissue_expression_up hsa-mir-106b Mesothelioma 21358347 "miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated" tissue_expression_up hsa-mir-17 Mesothelioma 21358347 "miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated" tissue_expression_up hsa-mir-18a Mesothelioma 21358347 "miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated" tissue_expression_up hsa-mir-19b-1 Mesothelioma 21358347 "miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated" tissue_expression_up hsa-mir-19b-2 Mesothelioma 21358347 "miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated" tissue_expression_up hsa-mir-20a Mesothelioma 21358347 "miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated" tissue_expression_up hsa-mir-20b Mesothelioma 21358347 "miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated" tissue_expression_up hsa-mir-25 Mesothelioma 21358347 "miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated" tissue_expression_up hsa-mir-92a-1 Mesothelioma 21358347 "miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated" tissue_expression_up hsa-mir-92a-2 Mesothelioma 21358347 "miR 17-5p, 18a, 19b, 20a, 20b, 25, 92, 106a, 106b, were markedly upregulated" tissue_expression_up hsa-mir-125b Psoriasis 21373745 "Real-time PCR and immunohistochemistry showed that p63 expression was not significantly affected, whereas NB-UVB phototherapy significantly decreased expression ofmiR-21 (p = 0.003) and increased miR-125b levels (p = 0.003). The results indicate that the unresolved p63 abnormality in treated epidermis may play a role in maintenance of this disease." tissue_expression_up hsa-mir-125a Retinoblastoma 21373755 "We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions." tissue_expression_up hsa-mir-181b-1 Retinoblastoma 21373755 "We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions." tissue_expression_up hsa-mir-181b-2 Retinoblastoma 21373755 "We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions." tissue_expression_up hsa-mir-30c-2 Retinoblastoma 21373755 "We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions." tissue_expression_up hsa-mir-491 Retinoblastoma 21373755 "We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions." tissue_expression_up hsa-mir-497 Retinoblastoma 21373755 "We identified a cluster of miRNAs that includes miR-181b, miR-125a-3p, miR-30c-2, miR-497 and miR-491-3p as hypoxia-regulated miRNAs (HRMs) in retinoblastoma cells, of which miR-181b was the most typically differentially expressed miRNA under hypoxic conditions." tissue_expression_up hsa-mir-18a Nasopharyngeal Neoplasms 21373758 overexpressed tissue_expression_up hsa-mir-210 Preeclampsia 21388517 Elevated levels of hypoxia-inducible microRNA-210 in pre-eclampsia: new insights into molecular mechanisms for the disease. tissue_expression_up hsa-mir-16-1 "Carcinoma, Lung, Non-Small-Cell" 21400525 miR-16 levels in tumor samples may be a prognostic marker in NSCLC. tissue_expression_up hsa-mir-16-2 "Carcinoma, Lung, Non-Small-Cell" 21400525 miR-16 levels in tumor samples may be a prognostic marker in NSCLC. tissue_expression_up hsa-mir-155 Mycosis Fungoides 21406335 upregulated in tumor stage MF compared to benign inflammatory dermatoses. tissue_expression_up hsa-mir-92a-1 Mycosis Fungoides 21406335 upregulated in tumor stage MF compared to benign inflammatory dermatoses. tissue_expression_up hsa-mir-92a-2 Mycosis Fungoides 21406335 upregulated in tumor stage MF compared to benign inflammatory dermatoses. tissue_expression_up hsa-mir-93 Mycosis Fungoides 21406335 upregulated in tumor stage MF compared to benign inflammatory dermatoses. tissue_expression_up hsa-mir-125b-1 Breast Neoplasms 21409395 "let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells" tissue_expression_up hsa-mir-125b-2 Breast Neoplasms 21409395 "let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells" tissue_expression_up hsa-mir-126 Breast Neoplasms 21409395 "let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells" tissue_expression_up hsa-mir-127 Breast Neoplasms 21409395 "let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells" tissue_expression_up hsa-mir-143 Breast Neoplasms 21409395 "let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells" tissue_expression_up hsa-mir-145 Breast Neoplasms 21409395 "let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells" tissue_expression_up hsa-mir-146b Breast Neoplasms 21409395 "let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells" tissue_expression_up hsa-mir-199a-1 Breast Neoplasms 21409395 "let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells" tissue_expression_up hsa-mir-199a-2 Breast Neoplasms 21409395 "let7c, miR-125b, miR-126, miR-127-3p, miR-143, miR-145, miR-146b-5p, and miR-199a-3p), preferentially expressed in normal basal cells" tissue_expression_up hsa-mir-200c Breast Neoplasms 21409395 "Both miR-200c and miR-429, two members of the miR-200 family were expressed in the luminal and basal type of breast cancer in contrast to malignant myoepithelioma." tissue_expression_up hsa-mir-429 Breast Neoplasms 21409395 "Both miR-200c and miR-429, two members of the miR-200 family were expressed in the luminal and basal type of breast cancer in contrast to malignant myoepithelioma." tissue_expression_up hsa-mir-155 Colorectal Carcinoma 21412018 High miR-155 expression was significantly correlated with lymph node metastases. The overall (OS) and disease-free survival (DFS) rates of patients with high miR-155 expression were also significantly worse than those in patients with low miR-155 expression. tissue_expression_up hsa-mir-21 Colorectal Carcinoma 21412018 "High miR-21 expression was significantly associated with venous invasion, liver metastasis and tumor stage.The overall (OS) and disease-free survival (DFS) rates of patients with high miR-21 expression were significantly worse than those of patients with low miR-21 expression." tissue_expression_up hsa-mir-21 Obesity 21426570 mir-21 is up-regulated in subcutaneous adipose tissue in human obesity tissue_expression_up hsa-mir-100 Endometriosis 21436257 up-regulated in endometriomas compared with endometrium. tissue_expression_up hsa-mir-193a Endometriosis 21436257 miR-193a-3p and miR-193a-5p up-regulated in endometriomas compared with endometrium. tissue_expression_up hsa-mir-202 Endometriosis 21436257 up-regulated in endometriomas compared with endometrium. tissue_expression_up hsa-mir-29c Endometriosis 21436257 up-regulated in endometriomas compared with endometrium. tissue_expression_up hsa-mir-485 Endometriosis 21436257 miR-485-3p up-regulated in endometriomas compared with endometrium. tissue_expression_up hsa-mir-509-3 Endometriosis 21436257 miR-509-3-5p up-regulated in endometriomas compared with endometrium. tissue_expression_up hsa-mir-574 Endometriosis 21436257 miR-574-3p up-regulated in endometriomas compared with endometrium. tissue_expression_up hsa-mir-708 Endometriosis 21436257 up-regulated in endometriomas compared with endometrium. tissue_expression_up hsa-mir-720 Endometriosis 21436257 up-regulated in endometriomas compared with endometrium. tissue_expression_up hsa-mir-143 "Diabetes Mellitus, Type 2" 21441927 Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. tissue_expression_up hsa-mir-143 Esophageal Neoplasms 21453382 The high levels of expression of mature MIR143 and mature MIR145 were associated with recurrence of metastasis in ESCC patients.The high expression of mature MIR21 and mature MIR205 was associated with lymph node positivity in ESCC patients (P < 0.05). tissue_expression_up hsa-mir-145 Esophageal Neoplasms 21453382 The high levels of expression of mature MIR143 and mature MIR145 were associated with recurrence of metastasis in ESCC patients.The high expression of mature MIR21 and mature MIR205 was associated with lymph node positivity in ESCC patients (P < 0.05). tissue_expression_up hsa-mir-205 Esophageal Neoplasms 21453382 The high levels of expression of mature MIR143 and mature MIR145 were associated with recurrence of metastasis in ESCC patients.The high expression of mature MIR21 and mature MIR205 was associated with lymph node positivity in ESCC patients (P < 0.05). tissue_expression_up hsa-mir-21 Esophageal Neoplasms 21453382 The high levels of expression of mature MIR143 and mature MIR145 were associated with recurrence of metastasis in ESCC patients.The high expression of mature MIR21 and mature MIR205 was associated with lymph node positivity in ESCC patients (P < 0.05). tissue_expression_up hsa-mir-223 Esophageal Neoplasms 21453483 miR-223 regulates migration and invasion by targeting Artemin in human esophageal carcinoma. tissue_expression_up hsa-mir-155 Multiple Sclerosis 21453702 Several miRNAs such as miR-155 or miR-326 are considerably overexpressed in active MS lesions versus controls tissue_expression_up hsa-mir-326 Multiple Sclerosis 21453702 Several miRNAs such as miR-155 or miR-326 are considerably overexpressed in active MS lesions versus controls tissue_expression_up hsa-mir-210 Sarcoma [unspecific] 21455991 Expression of microRNA 210 associates with poor survival and age of tumor onset of soft-tissue sarcoma patients. tissue_expression_up hsa-mir-221 "Carcinoma, Hepatocellular" 21458843 Deregulated expression of microRNA-221 with the potential for prognostic biomarkers in surgically resected hepatocellular carcinoma. tissue_expression_up hsa-mir-21 Pancreatic Neoplasms 21463919 "over-expression of Notch-1 leads to increased expression of miR-21, and decreased expression of miR-200b, miR-200c, let-7a, let-7b, and let-7c. over-expression of Notch-1 led to the induction of EMT phenotype" tissue_expression_up hsa-mir-141 Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-17 Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-183 Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-18a Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-19a Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-19b-1 Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-19b-2 Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-200a Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-200b Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-200c Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-20a Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-429 Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-92a-1 Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-92a-2 Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-96 Urinary Bladder Cancer 21464941 "Compared to matched histologically normal urothelium, upregulated." tissue_expression_up hsa-mir-210 "Carcinoma, Renal Cell" 21465485 "Overexpression of miR-210, a downstream target of HIF1, causes centrosome amplification in renal carcinoma cells." tissue_expression_up hsa-mir-146a Sjogren Syndrome 21469088 Altered miR-146a expression in Sjogren's syndrome tissue_expression_up hsa-mir-139 "Carcinoma, Adrenocortical" 21471143 "ACCs (adrenocortical carcinomas) exhibited significantly lower levels of miR-139-3p (up to 8.49-fold, p<0.001), miR-675 (up to 23.25-fold, p<0.001) and miR-335 (up to 5.25-fold, p<0.001)." tissue_expression_up hsa-mir-375 "Carcinoma, Adrenocortical" 21471143 "ACCs (adrenocortical carcinomas) exhibited significantly lower levels of miR-139-3p (up to 8.49-fold, p<0.001), miR-675 (up to 23.25-fold, p<0.001) and miR-335 (up to 5.25-fold, p<0.001)." tissue_expression_up hsa-mir-675 "Carcinoma, Adrenocortical" 21471143 "ACCs (adrenocortical carcinomas) exhibited significantly lower levels of miR-139-3p (up to 8.49-fold, p<0.001), miR-675 (up to 23.25-fold, p<0.001) and miR-335 (up to 5.25-fold, p<0.001)." tissue_expression_up hsa-mir-483 "Carcinoma, Adrenocortical" 21472710 "miRs -100, -125b, and -195 were significantly down-regulated, whereas miR-483-5p was significantly up-regulated in malignant as compared with benign tumors." tissue_expression_up hsa-mir-106a Glioblastoma 21483847 "miR-106aa upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma." tissue_expression_up hsa-mir-146b Glioblastoma 21483847 "miR-146b upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma." tissue_expression_up hsa-mir-148a Glioblastoma 21483847 "miR-148a upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma." tissue_expression_up hsa-mir-17 Glioblastoma 21483847 "miR-17-5p upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma." tissue_expression_up hsa-mir-193a Glioblastoma 21483847 "miR-193a upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma." tissue_expression_up hsa-mir-200b Glioblastoma 21483847 "miR-200b upregulated in Glioblastoma vs Normal. Ten miRNAs (miR-20a, miR-106a, miR-17-5p, miR-31, miR-222, miR-148a, miR-221, miR-146b, miR-200b, and miR-193a) could be a signature predicding survival in Glioblastoma." tissue_expression_up hsa-mir-106a Melanoma 21509659 significantly up-regulated in uveal melanomas compared with normal uveal tissues tissue_expression_up hsa-mir-17 Melanoma 21509659 significantly up-regulated in uveal melanomas compared with normal uveal tissues tissue_expression_up hsa-mir-20a Melanoma 21509659 significantly up-regulated in uveal melanomas compared with normal uveal tissues tissue_expression_up hsa-mir-21 Melanoma 21509659 significantly up-regulated in uveal melanomas compared with normal uveal tissues tissue_expression_up hsa-mir-34a Melanoma 21509659 significantly up-regulated in uveal melanomas compared with normal uveal tissues tissue_expression_up hsa-mir-21 Sezary Disease 21525938 "MicroRNA profiling reveals that miR-21, miR-486 and miR-214 are upregulated and involved in cell survival in Sezary Syndrome." tissue_expression_up hsa-mir-214 Sezary Disease 21525938 "MicroRNA profiling reveals that miR-21, miR-486 and miR-214 are upregulated and involved in cell survival in Sezary Syndrome." tissue_expression_up hsa-mir-486 Sezary Disease 21525938 "MicroRNA profiling reveals that miR-21, miR-486 and miR-214 are upregulated and involved in cell survival in Sezary Syndrome." tissue_expression_up hsa-mir-146b Thyroid Neoplasms 21537871 "miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC." tissue_expression_up hsa-mir-155 Thyroid Neoplasms 21537871 "miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC." tissue_expression_up hsa-mir-221 Thyroid Neoplasms 21537871 "miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC." tissue_expression_up hsa-mir-222 Thyroid Neoplasms 21537871 "miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC." tissue_expression_up hsa-mir-31 Thyroid Neoplasms 21537871 "miR-146b, miR-221, miR-222, miR-155, miR-31 upregulation and miR-1, miR-34b, miR-130b, miR-138 downregulation in aggressive compared with nonaggressive PTC." tissue_expression_up hsa-mir-20a Colorectal Carcinoma 21551242 "MiR-20a and miR-31 were found to be significantly upregulated in more than one study, and miR-143 and miR-145 were found to be significantly downregulated in CRC tissue in six or more studies." tissue_expression_up hsa-mir-31 Colorectal Carcinoma 21551242 "MiR-20a and miR-31 were found to be significantly upregulated in more than one study, and miR-143 and miR-145 were found to be significantly downregulated in CRC tissue in six or more studies." tissue_expression_up hsa-mir-126 Thyroid Neoplasms 21553140 miR-7 and miR-126 could be candidate diagnostic microRNAs for thyroid histologic subtypes. tissue_expression_up hsa-mir-7-1 Thyroid Neoplasms 21553140 miR-7 and miR-126 could be candidate diagnostic microRNAs for thyroid histologic subtypes. tissue_expression_up hsa-mir-7-2 Thyroid Neoplasms 21553140 miR-7 and miR-126 could be candidate diagnostic microRNAs for thyroid histologic subtypes. tissue_expression_up hsa-mir-7-3 Thyroid Neoplasms 21553140 miR-7 and miR-126 could be candidate diagnostic microRNAs for thyroid histologic subtypes. tissue_expression_up hsa-mir-101-1 Head And Neck Neoplasms 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_up hsa-mir-101-1 "Squamous Cell Carcinoma, Head and Neck" 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_up hsa-mir-101-2 Head And Neck Neoplasms 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_up hsa-mir-101-2 "Squamous Cell Carcinoma, Head and Neck" 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_up hsa-mir-181b-1 Head And Neck Neoplasms 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_up hsa-mir-181b-1 "Squamous Cell Carcinoma, Head and Neck" 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_up hsa-mir-181b-2 Head And Neck Neoplasms 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_up hsa-mir-181b-2 "Squamous Cell Carcinoma, Head and Neck" 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_up hsa-mir-181d Head And Neck Neoplasms 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_up hsa-mir-181d "Squamous Cell Carcinoma, Head and Neck" 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_up hsa-mir-195 Head And Neck Neoplasms 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_up hsa-mir-195 "Squamous Cell Carcinoma, Head and Neck" 21560177 "Docetaxel resistant cells showed significant downregulation of miR-100, miR-130a, and miR-197 and upregulation in miR-101, miR-181b, miR-181d, and miR-195 expression when compared with their parent cells (p < .01)." tissue_expression_up hsa-mir-9-1 Colorectal Carcinoma 21562850 MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility. tissue_expression_up hsa-mir-9-2 Colorectal Carcinoma 21562850 MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility. tissue_expression_up hsa-mir-9-3 Colorectal Carcinoma 21562850 MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility. tissue_expression_up hsa-let-7d Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_up hsa-let-7e Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_up hsa-mir-148b Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_up hsa-mir-199b Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_up hsa-mir-24-1 Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_up hsa-mir-331 Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_up hsa-mir-374a Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_up hsa-mir-96 Lung Neoplasms 21563230 "Specifically, thirteen novel asbestos-related miRNAs (over-expressed: miR-148b, miR-374a, miR-24-1*, Let-7d, Let-7e, miR-199b-5p, miR-331-3p, and miR-96 and under-expressed: miR-939, miR-671-5p, miR-605, miR-1224-5p and miR-202) and inversely correlated target genes (e.g., GADD45A, LTBP1, FOSB, NCALD, CACNA2D2, MTSS1, EPB41L3) were identified. " tissue_expression_up hsa-mir-34a Colorectal Carcinoma 21566225 The gene encoding the miR-34a microRNA is a transcriptional target of the p53 tumor suppressor protein and subject to epigenetic inactivation in colorectal cancer and numerous other tumor types tissue_expression_up hsa-mir-185 Colorectal Carcinoma 21573504 "High expression of miR-185 and low expression of miR-133b were correlated with poor survival (p=0.001 and 0.028, respectively) and metastasis (p=0.007 and 0.036, respectively) in colorectal cancer." tissue_expression_up hsa-mir-31 "Squamous Cell Carcinoma, Cerevial" 21590768 "miR-31 up-regulation in Drosha-overexpressing samples/cell lines was the highest-ranked change (by adjusted p value) in both analyses, an observation validated by northern blotting." tissue_expression_up hsa-mir-1207 Prostate Neoplasms 21592394 "Among these miR-22, miR-29ab, miR-134, miR-1207-5p and miR-371-5p are up regulated, while miR-17 and miR-20a, members of the miR-17/92 cluster are down regulated." tissue_expression_up hsa-mir-134 Prostate Neoplasms 21592394 "Among these miR-22, miR-29ab, miR-134, miR-1207-5p and miR-371-5p are up regulated, while miR-17 and miR-20a, members of the miR-17/92 cluster are down regulated." tissue_expression_up hsa-mir-22 Prostate Neoplasms 21592394 "Among these miR-22, miR-29ab, miR-134, miR-1207-5p and miR-371-5p are up regulated, while miR-17 and miR-20a, members of the miR-17/92 cluster are down regulated." tissue_expression_up hsa-mir-29a Prostate Neoplasms 21592394 "Among these miR-22, miR-29ab, miR-134, miR-1207-5p and miR-371-5p are up regulated, while miR-17 and miR-20a, members of the miR-17/92 cluster are down regulated." tissue_expression_up hsa-mir-29b Prostate Neoplasms 21592394 "Among these miR-22, miR-29ab, miR-134, miR-1207-5p and miR-371-5p are up regulated, while miR-17 and miR-20a, members of the miR-17/92 cluster are down regulated." tissue_expression_up hsa-mir-371 Prostate Neoplasms 21592394 "Among these miR-22, miR-29ab, miR-134, miR-1207-5p and miR-371-5p are up regulated, while miR-17 and miR-20a, members of the miR-17/92 cluster are down regulated." tissue_expression_up hsa-mir-126 Prostate Neoplasms 21594291 "In addition, anti-invasive microRNAs such as miR-335, miR-205, miR-200, and miR-126, were up-regulated, whereas pro-invasive microRNA such as miR-21 and miR-373, were down-regulated." tissue_expression_up hsa-mir-200 Prostate Neoplasms 21594291 "In addition, anti-invasive microRNAs such as miR-335, miR-205, miR-200, and miR-126, were up-regulated, whereas pro-invasive microRNA such as miR-21 and miR-373, were down-regulated." tissue_expression_up hsa-mir-205 Prostate Neoplasms 21594291 "In addition, anti-invasive microRNAs such as miR-335, miR-205, miR-200, and miR-126, were up-regulated, whereas pro-invasive microRNA such as miR-21 and miR-373, were down-regulated." tissue_expression_up hsa-mir-335 Prostate Neoplasms 21594291 "In addition, anti-invasive microRNAs such as miR-335, miR-205, miR-200, and miR-126, were up-regulated, whereas pro-invasive microRNA such as miR-21 and miR-373, were down-regulated." tissue_expression_up hsa-mir-126 Asthma 21605405 upregulated compared with normal control tissue_expression_up hsa-let-7b "Carcinoma, Lung, Non-Small-Cell" 21622546 "Eighteen cases were classified as AD and 13 as SCC by light microscopy and immunocytochemistry. miRNA expression profiles demonstrated considerable, statistically significant differences between AD and SCC, showing an upregulation of hsa-let-7a, hsa-let-7b, hsa-let-7c,hsa-let-7f, hsa-let-7g, hsa-let-7i, and hsa-miR-98 and a downregulation of hsa-miR-205 in AD specimens" tissue_expression_up hsa-let-7c "Carcinoma, Lung, Non-Small-Cell" 21622546 "Eighteen cases were classified as AD and 13 as SCC by light microscopy and immunocytochemistry. miRNA expression profiles demonstrated considerable, statistically significant differences between AD and SCC, showing an upregulation of hsa-let-7a, hsa-let-7b, hsa-let-7c,hsa-let-7f, hsa-let-7g, hsa-let-7i, and hsa-miR-98 and a downregulation of hsa-miR-205 in AD specimens" tissue_expression_up hsa-let-7f "Carcinoma, Lung, Non-Small-Cell" 21622546 "Eighteen cases were classified as AD and 13 as SCC by light microscopy and immunocytochemistry. miRNA expression profiles demonstrated considerable, statistically significant differences between AD and SCC, showing an upregulation of hsa-let-7a, hsa-let-7b, hsa-let-7c,hsa-let-7f, hsa-let-7g, hsa-let-7i, and hsa-miR-98 and a downregulation of hsa-miR-205 in AD specimens" tissue_expression_up hsa-let-7g "Carcinoma, Lung, Non-Small-Cell" 21622546 "Eighteen cases were classified as AD and 13 as SCC by light microscopy and immunocytochemistry. miRNA expression profiles demonstrated considerable, statistically significant differences between AD and SCC, showing an upregulation of hsa-let-7a, hsa-let-7b, hsa-let-7c,hsa-let-7f, hsa-let-7g, hsa-let-7i, and hsa-miR-98 and a downregulation of hsa-miR-205 in AD specimens" tissue_expression_up hsa-let-7i "Carcinoma, Lung, Non-Small-Cell" 21622546 "Eighteen cases were classified as AD and 13 as SCC by light microscopy and immunocytochemistry. miRNA expression profiles demonstrated considerable, statistically significant differences between AD and SCC, showing an upregulation of hsa-let-7a, hsa-let-7b, hsa-let-7c,hsa-let-7f, hsa-let-7g, hsa-let-7i, and hsa-miR-98 and a downregulation of hsa-miR-205 in AD specimens" tissue_expression_up hsa-mir-98 "Carcinoma, Lung, Non-Small-Cell" 21622546 "Eighteen cases were classified as AD and 13 as SCC by light microscopy and immunocytochemistry. miRNA expression profiles demonstrated considerable, statistically significant differences between AD and SCC, showing an upregulation of hsa-let-7a, hsa-let-7b, hsa-let-7c,hsa-let-7f, hsa-let-7g, hsa-let-7i, and hsa-miR-98 and a downregulation of hsa-miR-205 in AD specimens" tissue_expression_up hsa-mir-1271 Head And Neck Neoplasms 21637912 hsa-mir-1271 was upregulated compared with normal tissue. tissue_expression_up hsa-mir-181a-2 Head And Neck Neoplasms 21637912 hsa-mir-181a-2* was upregulated compared with normal tissue. tissue_expression_up hsa-mir-181b-1 Head And Neck Neoplasms 21637912 hsa-mir-181b was upregulated compared with normal tissue. tissue_expression_up hsa-mir-181b-2 Head And Neck Neoplasms 21637912 hsa-mir-181b was upregulated compared with normal tissue. tissue_expression_up hsa-mir-221 Head And Neck Neoplasms 21637912 hsa-mir-221* was upregulated compared with normal tissue. tissue_expression_up hsa-mir-744 Head And Neck Neoplasms 21637912 hsa-mir-744 was upregulated compared with normal tissue. tissue_expression_up hsa-mir-133b Lung Neoplasms 21648427 Mice treated with pre-miR-133b containing lipoplexes had mature miR-133b expression in lung ~52-fold higher than untreated mice. tissue_expression_up hsa-mir-31 "Squamous Cell Carcinoma, Esophageal" 21658006 miR-31 was up-regulated in 77.8% of the ESCC tissues. Serum miR-31 levels in ESCC patients were significantly higher than in normal controls (P<0.001). tissue_expression_up hsa-mir-106a "Carcinoma, Rectal" 21671476 "One of the most up-regulated miRNAs, miRNA-106a, was consistently reported to be differentially expressed in six studies and the five most down-regulated miRNAs, miR-30a-3p, miR-139, miR-145, miR-125a and miR-133a, were consistently reported to be differentially expressed in four studies." tissue_expression_up hsa-mir-155 Rheumatoid Arthritis 21690378 "miR-155 is up-regulated in synovial membrane and synovial fluid (SF) macrophages from patients with rheumatoid arthritis (RA). The increased expression of miR-155 in SF CD14(+) cells was associated with lower expression of the miR-155 target, Src homology 2-containing inositol phosphatase-1 (SHIP-1), an inhibitor of inflammation." tissue_expression_up hsa-let-7e Heart Failure 21690488 "The absolute expression levels of hcmv-miR-UL112, miR-296-5p, and let-7e were further determined in 127 patients and 67 control subjects (fold changes are 2.5, 0.5, and 1.7 respectively; all P<0.0001)." tissue_expression_up hsa-mir-122 Hepatitis B Virus Infection 21692939 Expression of the liver-specific miR-122 was significantly up-regulated in HBV-infected patients. tissue_expression_up hsa-mir-122 Liver Failure 21692939 The expression levels of miR-122 and miR-194 correlated negatively with the age of patients with CHB (chronic hepatitis B) or ACLF (acute-on-chronic liver failure). tissue_expression_up hsa-mir-194-1 Liver Failure 21692939 The expression levels of miR-122 and miR-194 correlated negatively with the age of patients with CHB (chronic hepatitis B) or ACLF (acute-on-chronic liver failure). tissue_expression_up hsa-mir-194-2 Liver Failure 21692939 The expression levels of miR-122 and miR-194 correlated negatively with the age of patients with CHB (chronic hepatitis B) or ACLF (acute-on-chronic liver failure). tissue_expression_up hsa-mir-148a Gastric Neoplasms 21703006 "miR-148a could reduce the invasiveness, migratory and adhesive activities of gastric tumor cells. Most importantly, elevated miR-148a level in gastric cancer tissues was strongly correlated with distant metastasis, organ and peritoneal invasion and reduced survival rate." tissue_expression_up hsa-mir-31 Kaposi Sarcoma 21715310 "In the present study, we show that Kaposi sarcoma-associated herpesvirus (KSHV), the etiological agent of KS, induces global miRNA changes in lymphatic endothelial cells (LECs). Specifically, the miR-221/miR-222 cluster is down-regulated, whereas miR-31 is up-regulated." tissue_expression_up hsa-mir-17 Gastrointestinal Neoplasms 21743960 Our study suggests that the presence of BM-DTCs and the upregulation of the miR-17-92 cluster in tumors are both significant but independent prognostic markers in gastrointestinal cancer patients. tissue_expression_up hsa-mir-18 Gastrointestinal Neoplasms 21743960 Our study suggests that the presence of BM-DTCs and the upregulation of the miR-17-92 cluster in tumors are both significant but independent prognostic markers in gastrointestinal cancer patients. tissue_expression_up hsa-mir-19a Gastrointestinal Neoplasms 21743960 Our study suggests that the presence of BM-DTCs and the upregulation of the miR-17-92 cluster in tumors are both significant but independent prognostic markers in gastrointestinal cancer patients. tissue_expression_up hsa-mir-19b-1 Gastrointestinal Neoplasms 21743960 Our study suggests that the presence of BM-DTCs and the upregulation of the miR-17-92 cluster in tumors are both significant but independent prognostic markers in gastrointestinal cancer patients. tissue_expression_up hsa-mir-20a Gastrointestinal Neoplasms 21743960 Our study suggests that the presence of BM-DTCs and the upregulation of the miR-17-92 cluster in tumors are both significant but independent prognostic markers in gastrointestinal cancer patients. tissue_expression_up hsa-mir-92-1 Gastrointestinal Neoplasms 21743960 Our study suggests that the presence of BM-DTCs and the upregulation of the miR-17-92 cluster in tumors are both significant but independent prognostic markers in gastrointestinal cancer patients. tissue_expression_up hsa-mir-215 Colorectal Carcinoma 21752725 miR-215 has a unique potential as a prognostic biomarker in stage II and III colon cancer. tissue_expression_up hsa-mir-21 "Adenocarcinoma, Pancreatic Ductal" 21757972 Elevated microRNA miR-21 Levels in Pancreatic Cyst Fluid Are Predictive of Mucinous Precursor Lesions of Ductal Adenocarcinoma. tissue_expression_up hsa-mir-155 "Carcinoma, Hepatocellular" 21762537 ectopic expression of miR-155 upregulated the expression of several IFN-inducible antivirus genes in human hepatoma cells. tissue_expression_up hsa-mir-106a Melanoma 21763111 "Early steps in skin tumor formation in HPV8-CER mice were associated with an upregulation of the oncogenic miRNA-17-5p, -21 and -106a and a downregulation of the tumor-suppressive miRNA-155 and -206, which could be demonstrated by qPCR and in situ hybridization." tissue_expression_up hsa-mir-17 Melanoma 21763111 "Early steps in skin tumor formation in HPV8-CER mice were associated with an upregulation of the oncogenic miRNA-17-5p, -21 and -106a and a downregulation of the tumor-suppressive miRNA-155 and -206, which could be demonstrated by qPCR and in situ hybridization." tissue_expression_up hsa-mir-21 Melanoma 21763111 "Early steps in skin tumor formation in HPV8-CER mice were associated with an upregulation of the oncogenic miRNA-17-5p, -21 and -106a and a downregulation of the tumor-suppressive miRNA-155 and -206, which could be demonstrated by qPCR and in situ hybridization." tissue_expression_up hsa-mir-21 Renal Fibrosis 21775484 miR-21 expression was upregulated in response to treatment with TGF-beta1 or TNF-alpha in human renal tubular epithelial cells in vitro. tissue_expression_up hsa-mir-181b "Carcinoma, Breast" 21779448 "we focused on miR-181b, which was overexpressed in several malignant neoplasias including breast carcinomas. " tissue_expression_up hsa-mir-122 Thyroid Neoplasms 21779480 The miRNA increased 8.9-fold (P < 0.05) in all Thyroid Neoplasms versus normal. tissue_expression_up hsa-mir-122 "Carcinoma, Renal Cell" 21784468 Overexpression tissue_expression_up hsa-mir-155 "Carcinoma, Renal Cell" 21784468 Overexpression tissue_expression_up hsa-mir-210 "Carcinoma, Renal Cell" 21784468 Overexpression tissue_expression_up hsa-mir-145 "Lymphoma, B-Cell" 21803762 miR-9 is upregulated. tissue_expression_up hsa-mir-17 "Lymphoma, B-Cell" 21803762 miR-17-5p is upregulated. tissue_expression_up hsa-mir-193b "Lymphoma, B-Cell" 21803762 miR-9 is upregulated. tissue_expression_up hsa-mir-199a-1 "Lymphoma, B-Cell" 21803762 miR-9 is upregulated. tissue_expression_up hsa-mir-199a-2 "Lymphoma, B-Cell" 21803762 miR-9 is upregulated. tissue_expression_up hsa-mir-20a "Lymphoma, B-Cell" 21803762 miR-20a is upregulated. tissue_expression_up hsa-mir-214 "Lymphoma, B-Cell" 21803762 miR-9 is upregulated. tissue_expression_up hsa-mir-9-1 "Lymphoma, B-Cell" 21803762 miR-9 is upregulated. tissue_expression_up hsa-mir-9-2 "Lymphoma, B-Cell" 21803762 miR-9 is upregulated. tissue_expression_up hsa-mir-9-3 "Lymphoma, B-Cell" 21803762 miR-9 is upregulated. tissue_expression_up hsa-mir-146a Rheumatoid Arthritis 21810022 "miRNA 146a expression was significantly higher in patients with RA than in those with OA and in controls.In patients with RA, miRNA 146a positively correlated with TNF-a (p=0.0003), erythrocyte sedimentation rate (ESR)(p=0.022), and DAS 28 (p=0.009)." tissue_expression_up hsa-mir-32 "Leukemia, Myeloid" 21816906 "MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis." tissue_expression_up hsa-let-7a-1 Colorectal Carcinoma 21826996 upregulated in colon cancer compared to normal colonic mucosa tissue_expression_up hsa-let-7a-2 Colorectal Carcinoma 21826996 upregulated in colon cancer compared to normal colonic mucosa tissue_expression_up hsa-let-7a-3 Colorectal Carcinoma 21826996 upregulated in colon cancer compared to normal colonic mucosa tissue_expression_up hsa-mir-106a Colorectal Carcinoma 21826996 upregulated in colon cancer compared to normal colonic mucosa tissue_expression_up hsa-mir-17 Colorectal Carcinoma 21826996 upregulated in colon cancer compared to normal colonic mucosa tissue_expression_up hsa-mir-182 Colorectal Carcinoma 21826996 upregulated in colon cancer compared to normal colonic mucosa tissue_expression_up hsa-mir-200c Colorectal Carcinoma 21826996 upregulated in colon cancer compared to normal colonic mucosa tissue_expression_up hsa-mir-20a Colorectal Carcinoma 21826996 upregulated in colon cancer compared to normal colonic mucosa tissue_expression_up hsa-mir-92a-1 Colorectal Carcinoma 21826996 upregulated in colon cancer compared to normal colonic mucosa tissue_expression_up hsa-mir-92a-2 Colorectal Carcinoma 21826996 upregulated in colon cancer compared to normal colonic mucosa tissue_expression_up hsa-mir-93 Colorectal Carcinoma 21826996 upregulated in colon cancer compared to normal colonic mucosa tissue_expression_up hsa-mir-491 Glioblastoma 21831363 "miR-491-5p has high positive correlation with MMP-9 expression and its upregulation was demonstrated to reduce the levels of MMP-9 expression and inhibit cellular invasion in U251 and U87 glioma cells. Furthermore, miR-491-5p suppressed glioma cell invasion via targeting MMP-9 directly." tissue_expression_up hsa-mir-885 Glioblastoma 21831363 miR-885-5p has high positive correlation with MMP-9 expression and its upregulation was demonstrated to reduce the levels of MMP-9 expression and inhibit cellular invasion in U251 and U87 glioma cells. tissue_expression_up hsa-mir-148a Alzheimer Disease 21834602 upregulated in bone marrow plasma cells from patients with immunoglobulin light chain (AL) amyloidosis compared with controls. tissue_expression_up hsa-mir-16-2 Alzheimer Disease 21834602 upregulated in bone marrow plasma cells from patients with immunoglobulin light chain (AL) amyloidosis compared with controls. tissue_expression_up hsa-mir-26a-1 Alzheimer Disease 21834602 upregulated in bone marrow plasma cells from patients with immunoglobulin light chain (AL) amyloidosis compared with controls. tissue_expression_up hsa-mir-26a-2 Alzheimer Disease 21834602 upregulated in bone marrow plasma cells from patients with immunoglobulin light chain (AL) amyloidosis compared with controls. tissue_expression_up hsa-mir-100 Muscular Dystrophy 21840938 highly expressed in fetal muscle. tissue_expression_up hsa-mir-127 Muscular Dystrophy 21840938 miR-127-3p: highly expressed in fetal muscle. tissue_expression_up hsa-mir-136 Muscular Dystrophy 21840938 miR-136*: highly expressed in fetal muscle. tissue_expression_up hsa-mir-148a Muscular Dystrophy 21840938 highly expressed in fetal muscle. tissue_expression_up hsa-mir-192 Muscular Dystrophy 21840938 highly expressed in fetal muscle. tissue_expression_up hsa-mir-335 Muscular Dystrophy 21840938 highly expressed in fetal muscle. tissue_expression_up hsa-mir-376c Muscular Dystrophy 21840938 highly expressed in fetal muscle. tissue_expression_up hsa-mir-489 Muscular Dystrophy 21840938 highly expressed in fetal muscle. tissue_expression_up hsa-mir-502 Muscular Dystrophy 21840938 miR-502-3p: highly expressed in fetal muscle. tissue_expression_up hsa-let-7f-2 Biliary Tract Neoplasms 21858175 The miRNA let-7f-2* was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-let-7i Biliary Tract Neoplasms 21858175 The miRNA let-7i* was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-105-1 Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-105-2 Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-145 Biliary Tract Neoplasms 21858175 The miRNA miR-145* was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-147b Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-199a-1 Biliary Tract Neoplasms 21858175 The miRNA miR-199a-3p was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-199a-2 Biliary Tract Neoplasms 21858175 The miRNA miR-199a-3p was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-222 Biliary Tract Neoplasms 21858175 The miRNA miR-222* was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-302c Biliary Tract Neoplasms 21858175 The miRNA miR-302c* was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-9-1 Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-9-2 Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-9-3 Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-942 Biliary Tract Neoplasms 21858175 The miRNA was significantly more highly expressed in the malignant group than in the benign group. tissue_expression_up hsa-mir-21 "Carcinoma, Adrenocortical" 21859927 "Among others, miR-483-3p, miR-483-5p, miR-210, and miR-21 were found overexpressed,while miR-195, miR-497, and miR-1974 were underexpressed in ACC. " tissue_expression_up hsa-mir-210 "Carcinoma, Adrenocortical" 21859927 "Among others, miR-483-3p, miR-483-5p, miR-210, and miR-21 were found overexpressed,while miR-195, miR-497, and miR-1974 were underexpressed in ACC. " tissue_expression_up hsa-mir-483 "Carcinoma, Adrenocortical" 21859927 "Among others, miR-483-3p, miR-483-5p, miR-210, and miR-21 were found overexpressed,while miR-195, miR-497, and miR-1974 were underexpressed in ACC. " tissue_expression_up hsa-mir-506 Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-507 Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-508 Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-509-1 Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-509-2 Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-509-3 Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-510 Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-513a-1 Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-513a-2 Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-513b Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-513c Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-514a-1 Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-514a-2 Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-514a-3 Melanoma 21860416 "miR-506-514 cluster was consistently overexpressed in nearly all melanomas tested (30-60 fold, P<0.001), regardless of mutations in N-ras or B-raf." tissue_expression_up hsa-mir-155 Melanoma 21863027 PCR analysis revealed primary cutaneous melanomas had an 8.6-fold overexpression of miR-21 and a 7.5-fold overexpression of miR-155 compared with benign naevi (P<0.0001). tissue_expression_up hsa-mir-21 Melanoma 21863027 PCR analysis revealed primary cutaneous melanomas had an 8.6-fold overexpression of miR-21 and a 7.5-fold overexpression of miR-155 compared with benign naevi (P<0.0001). tissue_expression_up hsa-mir-144 Colorectal Carcinoma 21863218 Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancer. tissue_expression_up hsa-mir-181b-1 Gastric Neoplasms 21876743 Doxifluridine/Oxaliplatin treated advanced stage gastric cancer patients. The expression of miR-181b and miR-21 was significantly overexpressed in gastric tumors compared to normal gastric tissues. tissue_expression_up hsa-mir-181b-2 Gastric Neoplasms 21876743 Doxifluridine/Oxaliplatin treated advanced stage gastric cancer patients. The expression of miR-181b and miR-21 was significantly overexpressed in gastric tumors compared to normal gastric tissues. tissue_expression_up hsa-mir-21 Gastric Neoplasms 21876743 Doxifluridine/Oxaliplatin treated advanced stage gastric cancer patients. The expression of miR-181b and miR-21 was significantly overexpressed in gastric tumors compared to normal gastric tissues. tissue_expression_up hsa-mir-142 "Squamous Cell Carcinoma, Esophageal" 21882196 "MiR-31 and miR-142-3p expression were correlated to histological differentiation in ESCC (P<0.05, Student's t-test); high miR-142-3p expression was associated with a poor prognosis in all 91 ESCC patients (P=0.014, log-rank) and identified as an independent prognostic factor in ESCC (P=0.017, univariate Cox; P=0.022, multivariate Cox). More importantly, stratified analysis indicated that high miR-142-3p expression was correlated to a poor prognosis within good-prognosis groups comprised of ESCC patients with small tumor size, negative lymph node metastasis, or early stage (all P<0.05)." tissue_expression_up hsa-mir-31 "Squamous Cell Carcinoma, Esophageal" 21882196 "MiR-31 and miR-142-3p expression were correlated to histological differentiation in ESCC (P<0.05, Student's t-test); high miR-142-3p expression was associated with a poor prognosis in all 91 ESCC patients (P=0.014, log-rank) and identified as an independent prognostic factor in ESCC (P=0.017, univariate Cox; P=0.022, multivariate Cox). More importantly, stratified analysis indicated that high miR-142-3p expression was correlated to a poor prognosis within good-prognosis groups comprised of ESCC patients with small tumor size, negative lymph node metastasis, or early stage (all P<0.05)." tissue_expression_up hsa-mir-21 "Squamous Cell Carcinoma, Esophageal" 21883657 miR-21 expression was significantly up-regulated in the whole spectrum of preneoplastic/neoplastic lesions considered. tissue_expression_up hsa-mir-133a-1 "Cardiomyopathy, Hypertrophic" 21893044 Hydrogen sulphide inhibits cardiomyocyte hypertrophy by up-regulating miR-133a. tissue_expression_up hsa-mir-133a-1 Hypertrophy 21893044 Hydrogen sulphide inhibits cardiomyocyte hypertrophy by up-regulating miR-133a tissue_expression_up hsa-mir-133a-2 "Cardiomyopathy, Hypertrophic" 21893044 Hydrogen sulphide inhibits cardiomyocyte hypertrophy by up-regulating miR-133a. tissue_expression_up hsa-mir-133a-2 Hypertrophy 21893044 Hydrogen sulphide inhibits cardiomyocyte hypertrophy by up-regulating miR-133a tissue_expression_up hsa-mir-141 Endometrial Neoplasms 21897839 "The entire miR-200 family (miR-200a/b/c, miR-141, and miR-429) was up-regulated in cases of EEC (endometrioid endometrial adenocarcinoma)." tissue_expression_up hsa-mir-200a Endometrial Neoplasms 21897839 "The entire miR-200 family (miR-200a/b/c, miR-141, and miR-429) was up-regulated in cases of EEC (endometrioid endometrial adenocarcinoma)." tissue_expression_up hsa-mir-200b Endometrial Neoplasms 21897839 "The entire miR-200 family (miR-200a/b/c, miR-141, and miR-429) was up-regulated in cases of EEC (endometrioid endometrial adenocarcinoma)." tissue_expression_up hsa-mir-200c Endometrial Neoplasms 21897839 "The entire miR-200 family (miR-200a/b/c, miR-141, and miR-429) was up-regulated in cases of EEC (endometrioid endometrial adenocarcinoma)." tissue_expression_up hsa-mir-429 Endometrial Neoplasms 21897839 "The entire miR-200 family (miR-200a/b/c, miR-141, and miR-429) was up-regulated in cases of EEC (endometrioid endometrial adenocarcinoma)." tissue_expression_up hsa-mir-141 "Carcinoma, Ehrlich Tumor" 21899346 "Two clusters miR-183~miR-96~miR-182 and miR-200b~miR-200a~miR-429 as well as miR-141 to be consistently up-regulated in the MDR (Multidrug resistance) cell lines, while miR-125b-5p and the two clusters miR-30d~miR-30b and miR-23b~miR-27b~miR-24-1 were down-regulated in most of the resistant EAT (Ehrlich ascites tumor) cells." tissue_expression_up hsa-mir-182 "Carcinoma, Ehrlich Tumor" 21899346 "Two clusters miR-183~miR-96~miR-182 and miR-200b~miR-200a~miR-429 as well as miR-141 to be consistently up-regulated in the MDR (Multidrug resistance) cell lines, while miR-125b-5p and the two clusters miR-30d~miR-30b and miR-23b~miR-27b~miR-24-1 were down-regulated in most of the resistant EAT (Ehrlich ascites tumor) cells." tissue_expression_up hsa-mir-183 "Carcinoma, Ehrlich Tumor" 21899346 "Two clusters miR-183~miR-96~miR-182 and miR-200b~miR-200a~miR-429 as well as miR-141 to be consistently up-regulated in the MDR (Multidrug resistance) cell lines, while miR-125b-5p and the two clusters miR-30d~miR-30b and miR-23b~miR-27b~miR-24-1 were down-regulated in most of the resistant EAT (Ehrlich ascites tumor) cells." tissue_expression_up hsa-mir-200a "Carcinoma, Ehrlich Tumor" 21899346 "Two clusters miR-183~miR-96~miR-182 and miR-200b~miR-200a~miR-429 as well as miR-141 to be consistently up-regulated in the MDR (Multidrug resistance) cell lines, while miR-125b-5p and the two clusters miR-30d~miR-30b and miR-23b~miR-27b~miR-24-1 were down-regulated in most of the resistant EAT (Ehrlich ascites tumor) cells." tissue_expression_up hsa-mir-200b "Carcinoma, Ehrlich Tumor" 21899346 "Two clusters miR-183~miR-96~miR-182 and miR-200b~miR-200a~miR-429 as well as miR-141 to be consistently up-regulated in the MDR (Multidrug resistance) cell lines, while miR-125b-5p and the two clusters miR-30d~miR-30b and miR-23b~miR-27b~miR-24-1 were down-regulated in most of the resistant EAT (Ehrlich ascites tumor) cells." tissue_expression_up hsa-mir-429 "Carcinoma, Ehrlich Tumor" 21899346 "Two clusters miR-183~miR-96~miR-182 and miR-200b~miR-200a~miR-429 as well as miR-141 to be consistently up-regulated in the MDR (Multidrug resistance) cell lines, while miR-125b-5p and the two clusters miR-30d~miR-30b and miR-23b~miR-27b~miR-24-1 were down-regulated in most of the resistant EAT (Ehrlich ascites tumor) cells." tissue_expression_up hsa-mir-96 "Carcinoma, Ehrlich Tumor" 21899346 "Two clusters miR-183~miR-96~miR-182 and miR-200b~miR-200a~miR-429 as well as miR-141 to be consistently up-regulated in the MDR (Multidrug resistance) cell lines, while miR-125b-5p and the two clusters miR-30d~miR-30b and miR-23b~miR-27b~miR-24-1 were down-regulated in most of the resistant EAT (Ehrlich ascites tumor) cells." tissue_expression_up hsa-mir-27b Glioblastoma 21922148 "Real-time PCR showed that miR-27b was up-regulated in glioma samples and glioma cells. Down-regulation of miR-27b triggered growth inhibition, induced apoptosis and inhibited invasion in glioma cells. In addition, Western blot assay showed that STAT3, c-myc and cyclin D1 were knocked down after treatment with miR-27b inhibitor." tissue_expression_up hsa-mir-27b Glioma 21922148 Real-time PCR showed that miR-27b was up-regulated in glioma samples and glioma cells. tissue_expression_up hsa-mir-21 Colorectal Carcinoma 21930727 "The expression of miR-21 and miR-92a was significantly higher in CRC tissues compared with their adjacent normal tissues (p<0.0001). Patients with CRC had a significantly higher stool miR-21 level (p<0.01) and miR-92a level (p<0.0001) compared with normal controls. Stool miR-92a, but not miR-21, was significantly higher in patients with polyps than in controls (p<0.0001). At a cut-off value of 435 copies/ng of stool RNA, miR-92a had a sensitivity of 71.6% and 56.1% for CRC and polyp, respectively, and a specificity of 73.3%. In addition, the stool miR-92a level demonstrated a higher sensitivity for distal CRC than proximal CRC (p<0.05), and a higher sensitivity for advanced adenoma than minor polyps (p<0.05). Removal of tumour resulted in reduced stool miR-21 and miR-92a levels (p<0.01), and the removal of advanced adenoma resulted in a reduction of the stool miR-92a level (p<0.05)." tissue_expression_up hsa-mir-92a-1 Colorectal Carcinoma 21930727 "The expression of miR-21 and miR-92a was significantly higher in CRC tissues compared with their adjacent normal tissues (p<0.0001). Patients with CRC had a significantly higher stool miR-21 level (p<0.01) and miR-92a level (p<0.0001) compared with normal controls. Stool miR-92a, but not miR-21, was significantly higher in patients with polyps than in controls (p<0.0001). At a cut-off value of 435 copies/ng of stool RNA, miR-92a had a sensitivity of 71.6% and 56.1% for CRC and polyp, respectively, and a specificity of 73.3%. In addition, the stool miR-92a level demonstrated a higher sensitivity for distal CRC than proximal CRC (p<0.05), and a higher sensitivity for advanced adenoma than minor polyps (p<0.05). Removal of tumour resulted in reduced stool miR-21 and miR-92a levels (p<0.01), and the removal of advanced adenoma resulted in a reduction of the stool miR-92a level (p<0.05)." tissue_expression_up hsa-mir-92a-2 Colorectal Carcinoma 21930727 "The expression of miR-21 and miR-92a was significantly higher in CRC tissues compared with their adjacent normal tissues (p<0.0001). Patients with CRC had a significantly higher stool miR-21 level (p<0.01) and miR-92a level (p<0.0001) compared with normal controls. Stool miR-92a, but not miR-21, was significantly higher in patients with polyps than in controls (p<0.0001). At a cut-off value of 435 copies/ng of stool RNA, miR-92a had a sensitivity of 71.6% and 56.1% for CRC and polyp, respectively, and a specificity of 73.3%. In addition, the stool miR-92a level demonstrated a higher sensitivity for distal CRC than proximal CRC (p<0.05), and a higher sensitivity for advanced adenoma than minor polyps (p<0.05). Removal of tumour resulted in reduced stool miR-21 and miR-92a levels (p<0.01), and the removal of advanced adenoma resulted in a reduction of the stool miR-92a level (p<0.05)." tissue_expression_up hsa-mir-126 Medulloblastoma 21931624 hsa-mir-126 was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-127 Medulloblastoma 21931624 hsa-mir-127-3p was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-143 Medulloblastoma 21931624 hsa-mir-143 was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-144 Medulloblastoma 21931624 hsa-mir-144* was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-145 Medulloblastoma 21931624 hsa-mir-145 was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-146a Medulloblastoma 21931624 hsa-mir-146a was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-193a Medulloblastoma 21931624 hsa-mir-193a-5p was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-203 Medulloblastoma 21931624 hsa-mir-203 was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-21 Medulloblastoma 21931624 hsa-mir-21* was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-223 Medulloblastoma 21931624 hsa-mir-223 was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-323a Medulloblastoma 21931624 hsa-mir-323-3p was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-338 Medulloblastoma 21931624 hsa-mir-338-3p was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-361 Medulloblastoma 21931624 hsa-mir-361-3p was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-376a-1 Medulloblastoma 21931624 hsa-mir-376 was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-376a-2 Medulloblastoma 21931624 hsa-mir-376 was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-376c Medulloblastoma 21931624 hsa-mir-376c was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-379 Medulloblastoma 21931624 hsa-mir-379 was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-409 Medulloblastoma 21931624 hsa-mir-409-3p was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-494 Medulloblastoma 21931624 hsa-mir-494 was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-495 Medulloblastoma 21931624 hsa-mir-495 was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-539 Medulloblastoma 21931624 hsa-mir-539 was significantly up-regulated in primary Medulloblastoma specimens relative to CD133+ NSCs (Neural Stem Cells). tissue_expression_up hsa-mir-1-1 Breast Neoplasms 21931769 "ATF-126 and Maspin cDNA induction led to the re-activation of tumor suppressive miRNAs also expressed in neural cells, such as miR-1 and miR-34, and to the down-regulation of potential oncogenic miRNAs, such as miR-10b, miR-124, and miR-363." tissue_expression_up hsa-mir-1-2 Breast Neoplasms 21931769 "ATF-126 and Maspin cDNA induction led to the re-activation of tumor suppressive miRNAs also expressed in neural cells, such as miR-1 and miR-34, and to the down-regulation of potential oncogenic miRNAs, such as miR-10b, miR-124, and miR-363." tissue_expression_up hsa-mir-34a Breast Neoplasms 21931769 "ATF-126 and Maspin cDNA induction led to the re-activation of tumor suppressive miRNAs also expressed in neural cells, such as miR-1 and miR-34, and to the down-regulation of potential oncogenic miRNAs, such as miR-10b, miR-124, and miR-363." tissue_expression_up hsa-mir-223 Breast Neoplasms 21939504 "miR-223, a miRNA specific for IL-4-activated macrophages, was detected within the exosomes released by macrophages and was significantly elevated in the co-cultivated SKBR3 and MDA-MB-231 cells." tissue_expression_up hsa-mir-1299 Ovarian Neoplasms 21939554 The miRNA was upregulated in cis-platin resistant (A2780/CP70) vs. cis-platin sensitive (A2780) ovarian cancer cell lines. tissue_expression_up hsa-mir-193b Ovarian Neoplasms 21939554 The miRNA was upregulated in cis-platin resistant (A2780/CP70) vs. cis-platin sensitive (A2780) ovarian cancer cell lines. tissue_expression_up hsa-mir-300 Ovarian Neoplasms 21939554 The miRNA was upregulated in cis-platin resistant (A2780/CP70) vs. cis-platin sensitive (A2780) ovarian cancer cell lines. tissue_expression_up hsa-mir-642a Ovarian Neoplasms 21939554 The miRNA was upregulated in cis-platin resistant (A2780/CP70) vs. cis-platin sensitive (A2780) ovarian cancer cell lines. tissue_expression_up hsa-let-7c Retinoblastoma 21941147 differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-let-7i Retinoblastoma 21941147 differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-10b Retinoblastoma 21941147 differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-124-1 Retinoblastoma 21941147 differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-124-2 Retinoblastoma 21941147 differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-124-3 Retinoblastoma 21941147 differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-135b Retinoblastoma 21941147 differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-142 Retinoblastoma 21941147 hsa-mir-142-5p: differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-29a Retinoblastoma 21941147 differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-29b-1 Retinoblastoma 21941147 differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-29b-2 Retinoblastoma 21941147 differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-29c Retinoblastoma 21941147 differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-34a Retinoblastoma 21941147 differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-34c Retinoblastoma 21941147 hsa-mir-34c-5p: differential expression between RB cell lines of different growth patterns: SNUOT-Rb1 with adherent and more rapid growth and Y79 with nonadherent and slower growth. tissue_expression_up hsa-mir-203 Lichen Planus 21943223 "Increased expression of miR-21 and miR-203, decreased expression of miR-125, and down-regulation of p53 and deltaNp63 RNA were seen in OLP compared to normal oral mucosa. When comparing microRNA expression to levels of p53 and p63 RNA, a significant negative correlation was seen between deltaNp63 and miR-203 and between miR-21 and p53, respectively." tissue_expression_up hsa-mir-21 Lichen Planus 21943223 "Increased expression of miR-21 and miR-203, decreased expression of miR-125, and down-regulation of p53 and deltaNp63 RNA were seen in OLP compared to normal oral mucosa. When comparing microRNA expression to levels of p53 and p63 RNA, a significant negative correlation was seen between deltaNp63 and miR-203 and between miR-21 and p53, respectively." tissue_expression_up hsa-mir-34c Alzheimer Disease 21946562 The authors identify miR-34c as a negative constraint of memory consolidation and show that miR-34c levels are elevated in the hippocampus of AD patients and corresponding mouse models. tissue_expression_up hsa-mir-182 Breast Neoplasms 21953071 The miRNA was up-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_up hsa-mir-183 Breast Neoplasms 21953071 The miRNA was up-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_up hsa-mir-203 Breast Neoplasms 21953071 The miRNA was up-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_up hsa-mir-375 Breast Neoplasms 21953071 The miRNA was up-regulated during lobular neoplasia progression compared to normal epithelium. Hsa-miR-375 is differentially expressed during breast lobular neoplasia and promotes loss of mammary acinar polarity. tissue_expression_up hsa-mir-425 Breast Neoplasms 21953071 miR-425-5p was up-regulated during lobular neoplasia progression compared to normal epithelium. tissue_expression_up hsa-mir-194-1 Pancreatic Neoplasms 21953293 Highly up-regulated in PDAC compared with normal ductal tissue_expression_up hsa-mir-194-2 Pancreatic Neoplasms 21953293 Highly up-regulated in PDAC compared with normal ductal tissue_expression_up hsa-mir-210 Pancreatic Neoplasms 21953293 Highly up-regulated in PDAC compared with normal ductal tissue_expression_up hsa-mir-425 Pancreatic Neoplasms 21953293 Highly up-regulated in PDAC compared with normal ductal tissue_expression_up hsa-mir-429 Pancreatic Neoplasms 21953293 Highly up-regulated in PDAC compared with normal ductal tissue_expression_up hsa-mir-210 Lung Neoplasms 21965273 Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1{alpha} tissue_expression_up hsa-mir-155 Mycosis Fungoides 21966986 "MiR-155 was only found to be slightly overexpressed in MF compared to healthy controls. Furthermore, metastatic MF demonstrated lower concentrations of let-7a, let-7d and let-7f when compared to MF limited to the skin." tissue_expression_up hsa-mir-106a Alopecia 21967250 "We detected the significant upregulation of miR-221, miR-125b, miR-106a and miR-410 in balding papilla cells." tissue_expression_up hsa-mir-125b Alopecia 21967250 "We detected the significant upregulation of miR-221, miR-125b, miR-106a and miR-410 in balding papilla cells." tissue_expression_up hsa-mir-221 Alopecia 21967250 "We detected the significant upregulation of miR-221, miR-125b, miR-106a and miR-410 in balding papilla cells." tissue_expression_up hsa-mir-410 Alopecia 21967250 "We detected the significant upregulation of miR-221, miR-125b, miR-106a and miR-410 in balding papilla cells." tissue_expression_up hsa-mir-21 Pancreatic Neoplasms 21983937 "miRNA-21 was the most significantly overexpressed miRNA in the pancreatic ductal adenocarcinomas analyzed, and was also highly expressed in 75% of the 65 pancreatic ductal adenocarcinomas examined by real-time RT-PCR. High miRNA-21 expression was correlated with a worse prognosis in the pancreatic ductal adenocarcinoma patients (P=0.045). The immunohistochemical expression patterns of PDCD4 (reduced nuclear staining pattern) and TIMP3 (downregulated expression) were significantly associated with both the upregulated miR-21 expression (P<0.05) and the poor survival of the patients (P<0.001 and P=0.001, respectively). Our data suggest that an overexpression of miRNA-21 is, therefore, associated with the biological behavior of pancreatic ductal adenocarcinoma via the downregulation of the expression of tumor suppressors, PDCD4 and TIMP3, thus resulting in tumor progression and the adverse clinical course of pancreatic ductal adenocarcinoma." tissue_expression_up hsa-mir-155 "Lymphoma, B-Cell" 21987025 "Four of miRNAs (miR-15a, miR-16-1, miR-29c, and miR-155) were significantly elevated in DLBCL (diffuse large B cell lymphoma) serum when compared with normal controls (P<0.05), while miR-34a was downregulated in DLBCL serum when compared with controls (P<0.05). Receiver operating characteristic analyses reflects strong discriminating DLBCL from controls, with area under the curves of 0.7722, 0.7002, 0.6672, 0.8538, and 0.7157 for miR-15a, miR-16-1, miR-29c, miR-34a, and miR-155, respectively. At the cut-off value of 0.0006 for miR-15a, the sensitivity was 80% and the specificity was 76%; at the cut-off value of 0.0886 for miR-16-1, the sensitivity was 94% and the specificity was 51%; at the cut-off value of 1.395 for miR-34a, the sensitivity was 100% and the specificity was 70%; at the cut-off value of 0.0022 for miR-155, the sensitivity was 83% and the specificity was 65%." tissue_expression_up hsa-mir-15a "Lymphoma, B-Cell" 21987025 "Four of miRNAs (miR-15a, miR-16-1, miR-29c, and miR-155) were significantly elevated in DLBCL (diffuse large B cell lymphoma) serum when compared with normal controls (P<0.05), while miR-34a was downregulated in DLBCL serum when compared with controls (P<0.05). Receiver operating characteristic analyses reflects strong discriminating DLBCL from controls, with area under the curves of 0.7722, 0.7002, 0.6672, 0.8538, and 0.7157 for miR-15a, miR-16-1, miR-29c, miR-34a, and miR-155, respectively. At the cut-off value of 0.0006 for miR-15a, the sensitivity was 80% and the specificity was 76%; at the cut-off value of 0.0886 for miR-16-1, the sensitivity was 94% and the specificity was 51%; at the cut-off value of 1.395 for miR-34a, the sensitivity was 100% and the specificity was 70%; at the cut-off value of 0.0022 for miR-155, the sensitivity was 83% and the specificity was 65%." tissue_expression_up hsa-mir-16-1 "Lymphoma, B-Cell" 21987025 "Four of miRNAs (miR-15a, miR-16-1, miR-29c, and miR-155) were significantly elevated in DLBCL (diffuse large B cell lymphoma) serum when compared with normal controls (P<0.05), while miR-34a was downregulated in DLBCL serum when compared with controls (P<0.05). Receiver operating characteristic analyses reflects strong discriminating DLBCL from controls, with area under the curves of 0.7722, 0.7002, 0.6672, 0.8538, and 0.7157 for miR-15a, miR-16-1, miR-29c, miR-34a, and miR-155, respectively. At the cut-off value of 0.0006 for miR-15a, the sensitivity was 80% and the specificity was 76%; at the cut-off value of 0.0886 for miR-16-1, the sensitivity was 94% and the specificity was 51%; at the cut-off value of 1.395 for miR-34a, the sensitivity was 100% and the specificity was 70%; at the cut-off value of 0.0022 for miR-155, the sensitivity was 83% and the specificity was 65%." tissue_expression_up hsa-mir-29c "Lymphoma, B-Cell" 21987025 "Four of miRNAs (miR-15a, miR-16-1, miR-29c, and miR-155) were significantly elevated in DLBCL (diffuse large B cell lymphoma) serum when compared with normal controls (P<0.05), while miR-34a was downregulated in DLBCL serum when compared with controls (P<0.05). Receiver operating characteristic analyses reflects strong discriminating DLBCL from controls, with area under the curves of 0.7722, 0.7002, 0.6672, 0.8538, and 0.7157 for miR-15a, miR-16-1, miR-29c, miR-34a, and miR-155, respectively. At the cut-off value of 0.0006 for miR-15a, the sensitivity was 80% and the specificity was 76%; at the cut-off value of 0.0886 for miR-16-1, the sensitivity was 94% and the specificity was 51%; at the cut-off value of 1.395 for miR-34a, the sensitivity was 100% and the specificity was 70%; at the cut-off value of 0.0022 for miR-155, the sensitivity was 83% and the specificity was 65%." tissue_expression_up hsa-mir-146a Systemic Lupus Erythematosus 21987229 "The levels of urinary miR-146a and miR-155 in patients with SLE were significantly higher than that in healthy controls. Calcitriol treatment reduced the levels of urinary miR-155 in patients with SLE. The level of urinary miR-146a significantly correlated with estimated glomerular filtration rate. The level of urinary miR-155 significantly correlated with proteinuria and systemic lupus erythematosus disease activity index (r=0.278, P=0.002). The level of urinary miR-146a reversely correlated with the urinary expression of TNF-a. Our results suggested that miR-146a and miR-155 might play important roles in the pathophysiology of SLE and the levels of urinary miR-146a and miR-155 could be used as potential markers for diagnosis, disease activity, and therapeutic response." tissue_expression_up hsa-mir-155 Systemic Lupus Erythematosus 21987229 "The levels of urinary miR-146a and miR-155 in patients with SLE were significantly higher than that in healthy controls. Calcitriol treatment reduced the levels of urinary miR-155 in patients with SLE. The level of urinary miR-146a significantly correlated with estimated glomerular filtration rate. The level of urinary miR-155 significantly correlated with proteinuria and systemic lupus erythematosus disease activity index (r=0.278, P=0.002). The level of urinary miR-146a reversely correlated with the urinary expression of TNF-a. Our results suggested that miR-146a and miR-155 might play important roles in the pathophysiology of SLE and the levels of urinary miR-146a and miR-155 could be used as potential markers for diagnosis, disease activity, and therapeutic response." tissue_expression_up hsa-mir-96 Urinary Bladder Cancer 21993544 hsa-mir-96 up-regulates MAP4K1 and IRS1 and may function as a promising diagnostic marker in human bladder urothelial carcinomas. tissue_expression_up hsa-mir-1224 "Carcinoma, Hepatocellular" 21998738 hsa-mir-1224-3p was up-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_up hsa-mir-1234 "Carcinoma, Hepatocellular" 21998738 hsa-mir-1234 was up-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_up hsa-mir-1249 "Carcinoma, Hepatocellular" 21998738 hsa-mir-1249 was up-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_up hsa-mir-15b "Carcinoma, Hepatocellular" 21998738 hsa-mir-15b* was up-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_up hsa-mir-197 "Carcinoma, Hepatocellular" 21998738 hsa-mir-197 was up-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_up hsa-mir-449b "Carcinoma, Hepatocellular" 21998738 hsa-mir-449b* was up-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_up hsa-mir-522 "Carcinoma, Hepatocellular" 21998738 hsa-mir-522 was up-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_up hsa-mir-532 "Carcinoma, Hepatocellular" 21998738 hsa-mir-532-3p was up-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_up hsa-mir-744 "Carcinoma, Hepatocellular" 21998738 hsa-mir-744* was up-regulated in HepG2 cells after 5 hours of culture with grape seed proanthocyanidin extract. tissue_expression_up hsa-mir-146a Osteoarthritis 22006119 "The relative expression levels of miR-146a, 155, 181a, and 223 in the OA patients were significantly higher than those found in healthy controls. In the early stages of OA, miR-146a and 223 expressions were significantly higher than they were at later stages. There was a significant correlation between the expression of miR-223 and KS. This study demonstrated that high expression levels of miR-146a, 155, 181a, and 223 in the PBMCs of OA patients might be related to the pathogenesis of OA." tissue_expression_up hsa-mir-155 Osteoarthritis 22006119 "The relative expression levels of miR-146a, 155, 181a, and 223 in the OA patients were significantly higher than those found in healthy controls. In the early stages of OA, miR-146a and 223 expressions were significantly higher than they were at later stages. There was a significant correlation between the expression of miR-223 and KS. This study demonstrated that high expression levels of miR-146a, 155, 181a, and 223 in the PBMCs of OA patients might be related to the pathogenesis of OA." tissue_expression_up hsa-mir-181a-1 Osteoarthritis 22006119 "The relative expression levels of miR-146a, 155, 181a, and 223 in the OA patients were significantly higher than those found in healthy controls. In the early stages of OA, miR-146a and 223 expressions were significantly higher than they were at later stages. There was a significant correlation between the expression of miR-223 and KS. This study demonstrated that high expression levels of miR-146a, 155, 181a, and 223 in the PBMCs of OA patients might be related to the pathogenesis of OA." tissue_expression_up hsa-mir-181a-2 Osteoarthritis 22006119 "The relative expression levels of miR-146a, 155, 181a, and 223 in the OA patients were significantly higher than those found in healthy controls. In the early stages of OA, miR-146a and 223 expressions were significantly higher than they were at later stages. There was a significant correlation between the expression of miR-223 and KS. This study demonstrated that high expression levels of miR-146a, 155, 181a, and 223 in the PBMCs of OA patients might be related to the pathogenesis of OA." tissue_expression_up hsa-mir-223 Osteoarthritis 22006119 "The relative expression levels of miR-146a, 155, 181a, and 223 in the OA patients were significantly higher than those found in healthy controls. In the early stages of OA, miR-146a and 223 expressions were significantly higher than they were at later stages. There was a significant correlation between the expression of miR-223 and KS. This study demonstrated that high expression levels of miR-146a, 155, 181a, and 223 in the PBMCs of OA patients might be related to the pathogenesis of OA." tissue_expression_up hsa-mir-100 Thyroid Neoplasms 22006248 "miR-100, miR-125b, miR-138, and miR-768-3p were overexpressed in malignant samples of follicular origin (P <0.001), and in Hurthle cell carcinoma samples alone (P < 0.01). Only miR-125b was significantly overexpressed in follicular carcinoma samples (P < .05)." tissue_expression_up hsa-mir-125b-1 Thyroid Neoplasms 22006248 "miR-100, miR-125b, miR-138, and miR-768-3p were overexpressed in malignant samples of follicular origin (P < .001), and in Hurthle cell carcinoma samples alone (P < .01). Only miR-125b was significantly overexpressed in follicular carcinoma samples (P < .05)." tissue_expression_up hsa-mir-125b-2 Thyroid Neoplasms 22006248 "miR-100, miR-125b, miR-138, and miR-768-3p were overexpressed in malignant samples of follicular origin (P < .001), and in Hurthle cell carcinoma samples alone (P < .01). Only miR-125b was significantly overexpressed in follicular carcinoma samples (P < .05)." tissue_expression_up hsa-mir-138-1 Thyroid Neoplasms 22006248 "miR-100, miR-125b, miR-138, and miR-768-3p were overexpressed in malignant samples of follicular origin (P < .001), and in Hurthle cell carcinoma samples alone (P < .01). Only miR-125b was significantly overexpressed in follicular carcinoma samples (P < .05)." tissue_expression_up hsa-mir-138-2 Thyroid Neoplasms 22006248 "miR-100, miR-125b, miR-138, and miR-768-3p were overexpressed in malignant samples of follicular origin (P < .001), and in Hurthle cell carcinoma samples alone (P < .01). Only miR-125b was significantly overexpressed in follicular carcinoma samples (P < .05)." tissue_expression_up hsa-let-7a-1 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-let-7a-2 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-let-7a-3 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-105-1 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-105-2 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-106a "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-10b "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-146a "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-148b "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-17 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-182 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-193a "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-196a-1 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-196a-2 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-205 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-21 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-210 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-217 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-222 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-25 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-29a "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-302b "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-302c "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-30a "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-34c "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-372 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-376a-1 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-376a-2 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-379 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-432 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-450a-1 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-450a-2 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-450b "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-493 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-508 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-517c "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-519e "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-96 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-98 "Carcinoma, Hepatocellular" 22027761 This miRNA was up-regulated in HepG2 cells treated with BJA32515. tissue_expression_up hsa-mir-223 Rheumatoid Arthritis 22032299 miR-223 is overexpressed in T-lymphocytes of early rheumatoid arthritis patients. tissue_expression_up hsa-mir-146a Sjogren Syndrome 22033216 "We found that both miR-146a and miR-146b, furthermore, the gene of TRAF6 were significantly overexpressed in the Sjogren's patients, whereas the expression of IRAK1 gene was significantly decreased." tissue_expression_up hsa-mir-146b Sjogren Syndrome 22033216 "We found that both miR-146a and miR-146b, furthermore, the gene of TRAF6 were significantly overexpressed in the Sjogren's patients, whereas the expression of IRAK1 gene was significantly decreased." tissue_expression_up hsa-mir-21 "Cardiomyopathy, Dilated" 22041329 "Levels of let-7i, miR-126, and miR-155 were lower in the DCM group than in the controls, whereas levels of miR-21 and TLR4 (both mRNA and protein) were higher in the DCM group than in the control group. Levels of let-7i were negatively correlated with TLR4 protein levels in all subjects. After a mean follow-up period of 509 days, 6 DCM patients (5.8%) had died due to a cardiac cause and 15 (14.6%) had developed heart failure. When patients with DCM were divided into tertiles according to let-7i levels, log-rank analysis showed that the DCM subgroup with low let-7i levels was associated with poor clinical outcomes (P = .02)." tissue_expression_up hsa-mir-1300 Pancreatic Neoplasms 22042419 "Among aberrantly expressed 122 microRNAs in IPMN, miR-552, miR-25*, miR-183, miR-1300, miR-196a, miR-182*, and miR-30c-1* were consistently increased more than 3-fold." tissue_expression_up hsa-mir-182 Pancreatic Neoplasms 22042419 "Among aberrantly expressed 122 microRNAs in IPMN, miR-552, miR-25*, miR-183, miR-1300, miR-196a, miR-182*, and miR-30c-1* were consistently increased more than 3-fold." tissue_expression_up hsa-mir-183 Pancreatic Neoplasms 22042419 "Among aberrantly expressed 122 microRNAs in IPMN, miR-552, miR-25*, miR-183, miR-1300, miR-196a, miR-182*, and miR-30c-1* were consistently increased more than 3-fold." tissue_expression_up hsa-mir-196a Pancreatic Neoplasms 22042419 "Among aberrantly expressed 122 microRNAs in IPMN, miR-552, miR-25*, miR-183, miR-1300, miR-196a, miR-182*, and miR-30c-1* were consistently increased more than 3-fold." tissue_expression_up hsa-mir-25 Pancreatic Neoplasms 22042419 "Among aberrantly expressed 122 microRNAs in IPMN, miR-552, miR-25*, miR-183, miR-1300, miR-196a, miR-182*, and miR-30c-1* were consistently increased more than 3-fold." tissue_expression_up hsa-mir-30c Pancreatic Neoplasms 22042419 "Among aberrantly expressed 122 microRNAs in IPMN, miR-552, miR-25*, miR-183, miR-1300, miR-196a, miR-182*, and miR-30c-1* were consistently increased more than 3-fold." tissue_expression_up hsa-mir-552 Pancreatic Neoplasms 22042419 "Among aberrantly expressed 122 microRNAs in IPMN, miR-552, miR-25*, miR-183, miR-1300, miR-196a, miR-182*, and miR-30c-1* were consistently increased more than 3-fold." tissue_expression_up hsa-mir-106b Periodontal Diseases 22043006 "Two microRNA species (miR-30e, miR-106b) were up-regulated in non-obese individuals with periodontal disease." tissue_expression_up hsa-mir-18a Obesity 22043006 "Two microRNA species (miR-18a, miR-30e) were up-regulated among obese individuals with a healthy periodontium." tissue_expression_up hsa-mir-30e Obesity 22043006 "Two microRNA species (miR-18a, miR-30e) were up-regulated among obese individuals with a healthy periodontium." tissue_expression_up hsa-mir-30e Periodontal Diseases 22043006 "Two microRNA species (miR-30e, miR-106b) were up-regulated in non-obese individuals with periodontal disease." tissue_expression_up hsa-mir-101 Colon Neoplasms 22043014 "The development of colonic inflammation in IL-10(-/-) mice was accompanied by upregulation in the expression of 10 miRNAs (miR-19a, miR-21, miR-31, miR-101, miR-223, miR-326, miR-142-3p, miR-142-5p, miR-146a, and miR-155)" tissue_expression_up hsa-mir-142 Colon Neoplasms 22043014 "The development of colonic inflammation in IL-10(-/-) mice was accompanied by upregulation in the expression of 10 miRNAs (miR-19a, miR-21, miR-31, miR-101, miR-223, miR-326, miR-142-3p, miR-142-5p, miR-146a, and miR-155)" tissue_expression_up hsa-mir-146a Colon Neoplasms 22043014 "The development of colonic inflammation in IL-10(-/-) mice was accompanied by upregulation in the expression of 10 miRNAs (miR-19a, miR-21, miR-31, miR-101, miR-223, miR-326, miR-142-3p, miR-142-5p, miR-146a, and miR-155)" tissue_expression_up hsa-mir-155 Colon Neoplasms 22043014 "The development of colonic inflammation in IL-10(-/-) mice was accompanied by upregulation in the expression of 10 miRNAs (miR-19a, miR-21, miR-31, miR-101, miR-223, miR-326, miR-142-3p, miR-142-5p, miR-146a, and miR-155)" tissue_expression_up hsa-mir-19a Colon Neoplasms 22043014 "The development of colonic inflammation in IL-10(-/-) mice was accompanied by upregulation in the expression of 10 miRNAs (miR-19a, miR-21, miR-31, miR-101, miR-223, miR-326, miR-142-3p, miR-142-5p, miR-146a, and miR-155)" tissue_expression_up hsa-mir-21 Colon Neoplasms 22043014 "The development of colonic inflammation in IL-10(-/-) mice was accompanied by upregulation in the expression of 10 miRNAs (miR-19a, miR-21, miR-31, miR-101, miR-223, miR-326, miR-142-3p, miR-142-5p, miR-146a, and miR-155)" tissue_expression_up hsa-mir-223 Colon Neoplasms 22043014 "The development of colonic inflammation in IL-10(-/-) mice was accompanied by upregulation in the expression of 10 miRNAs (miR-19a, miR-21, miR-31, miR-101, miR-223, miR-326, miR-142-3p, miR-142-5p, miR-146a, and miR-155)" tissue_expression_up hsa-mir-31 Colon Neoplasms 22043014 "The development of colonic inflammation in IL-10(-/-) mice was accompanied by upregulation in the expression of 10 miRNAs (miR-19a, miR-21, miR-31, miR-101, miR-223, miR-326, miR-142-3p, miR-142-5p, miR-146a, and miR-155)" tissue_expression_up hsa-mir-326 Colon Neoplasms 22043014 "The development of colonic inflammation in IL-10(-/-) mice was accompanied by upregulation in the expression of 10 miRNAs (miR-19a, miR-21, miR-31, miR-101, miR-223, miR-326, miR-142-3p, miR-142-5p, miR-146a, and miR-155)" tissue_expression_up hsa-mir-210 "Carcinoma, Renal Cell" 22043236 "For miR-92a, and a striking inverse correlation with VHL mRNA levels was found. For the hypoxia-regulated miR-210, clear cell tumors showed significantly higher expression levels when compared to tumor of non-clear cell histology (9.90-fold vs. 1.36, p<0.001)." tissue_expression_up hsa-mir-92a-1 "Carcinoma, Renal Cell" 22043236 "For miR-92a, and a striking inverse correlation with VHL mRNA levels was found. For the hypoxia-regulated miR-210, clear cell tumors showed significantly higher expression levels when compared to tumor of non-clear cell histology (9.90-fold vs. 1.36, p<0.001)." tissue_expression_up hsa-mir-92a-2 "Carcinoma, Renal Cell" 22043236 "For miR-92a, and a striking inverse correlation with VHL mRNA levels was found. For the hypoxia-regulated miR-210, clear cell tumors showed significantly higher expression levels when compared to tumor of non-clear cell histology (9.90-fold vs. 1.36, p<0.001)." tissue_expression_up hsa-mir-146a Creutzfeldt-Jakob Disease 22043907 "Upregulation of micro RNA-146a (miRNA-146a), a marker for inflammatory neurodegeneration, in sporadic Creutzfeldt-Jakob disease (sCJD) and Gerstmann-Straussler-Scheinker (GSS) syndrome." tissue_expression_up hsa-mir-146a Gerstmann-Straussler-Scheinker Syndrome 22043907 "Upregulation of micro RNA-146a (miRNA-146a), a marker for inflammatory neurodegeneration, in sporadic Creutzfeldt-Jakob disease (sCJD) and Gerstmann-Straussler-Scheinker (GSS) syndrome." tissue_expression_up hsa-mir-182 Prostate Neoplasms 22045813 The miR-183-96-182 cluster is overexpressed in prostate tissue and regulates zinc homeostasis in prostate cells. tissue_expression_up hsa-mir-183 Prostate Neoplasms 22045813 The miR-183-96-182 cluster is overexpressed in prostate tissue and regulates zinc homeostasis in prostate cells. tissue_expression_up hsa-mir-96 Prostate Neoplasms 22045813 The miR-183-96-182 cluster is overexpressed in prostate tissue and regulates zinc homeostasis in prostate cells. tissue_expression_up hsa-mir-195 Gastric Neoplasms 22046085 "Three miRs, miR-451, miR-199a-3p and miR-195 were found to be differentially expressed in tumors from patients with good prognosis vs patients with bad prognosis (P < 0.0002, 0.0027 and 0.0046 respectively). High expression of each miR was associated with poorer prognosis for both recurrence and survival. Using miR-451, the positive predictive value for non-recurrence was 100% (13/13)." tissue_expression_up hsa-mir-199a-1 Gastric Neoplasms 22046085 "Three miRs, miR-451, miR-199a-3p and miR-195 were found to be differentially expressed in tumors from patients with good prognosis vs patients with bad prognosis (P < 0.0002, 0.0027 and 0.0046 respectively). High expression of each miR was associated with poorer prognosis for both recurrence and survival. Using miR-451, the positive predictive value for non-recurrence was 100% (13/13)." tissue_expression_up hsa-mir-199a-2 Gastric Neoplasms 22046085 "Three miRs, miR-451, miR-199a-3p and miR-195 were found to be differentially expressed in tumors from patients with good prognosis vs patients with bad prognosis (P < 0.0002, 0.0027 and 0.0046 respectively). High expression of each miR was associated with poorer prognosis for both recurrence and survival. Using miR-451, the positive predictive value for non-recurrence was 100% (13/13)." tissue_expression_up hsa-mir-451a Gastric Neoplasms 22046085 "Three miRs, miR-451, miR-199a-3p and miR-195 were found to be differentially expressed in tumors from patients with good prognosis vs patients with bad prognosis (P < 0.0002, 0.0027 and 0.0046 respectively). High expression of each miR was associated with poorer prognosis for both recurrence and survival. Using miR-451, the positive predictive value for non-recurrence was 100% (13/13)." tissue_expression_up hsa-mir-96 "Carcinoma, Lung, Non-Small-Cell" 22046296 hsa-mir-96 is significantly and consistently up-regulated in all 6 NSCLCs. tissue_expression_up hsa-mir-135a-1 Ependymoma 22053178 overexpression tissue_expression_up hsa-mir-135a-2 Ependymoma 22053178 overexpression tissue_expression_up hsa-mir-17 Ependymoma 22053178 miR-17-5p: overexpression tissue_expression_up hsa-mir-10b Breast Neoplasms 22057972 "High level of miR-21, miR-10b, and miR-31 expression in bilateral vs. unilateral breast carcinomas." tissue_expression_up hsa-mir-21 Breast Neoplasms 22057972 "High level of miR-21, miR-10b, and miR-31 expression in bilateral vs. unilateral breast carcinomas." tissue_expression_up hsa-mir-31 Breast Neoplasms 22057972 "High level of miR-21, miR-10b, and miR-31 expression in bilateral vs. unilateral breast carcinomas." tissue_expression_up hsa-mir-3163 Glioblastoma 22074483 "Significantly deregulated miRNAs were miR-3163 (fold change 2.0, p = 0.05), miR-539 (fold change 0.5, p = 0.001), miR-1305 (fold change 0.5, p = 0.05), miR-1260 (fold change 0.5, p = 0.03) and let-7a (fold change 0.3, p = 0.02) after temozolomide treatment." tissue_expression_up hsa-mir-31 "Carcinoma, Oral" 22083872 "Salivary miR-31 was significantly increased in patients with oral carcinoma at all clinical stages, including very small tumors. However, our preliminary analysis showed no increase of salivary miR-31in patients with oral verrucous leukoplakia relative to controls. The miR-31 was more abundant in saliva than in plasma, suggesting salivary miR-31 was a more sensitive marker for oral malignancy. After excision of oral carcinoma, salivary miR-31 was remarkably reduced, indicating that most of the upregulated salivary miR-31 came from tumor tissues." tissue_expression_up hsa-mir-128-1 Multiple Sclerosis 22088562 "miR-128 and miR-27b were increased in naive and miR-340 in memory CD4(+) T cells from patients with multiple sclerosis, inhibiting Th2 cell development and favouring pro-inflammatory Th1 responses." tissue_expression_up hsa-mir-128-2 Multiple Sclerosis 22088562 "miR-128 and miR-27b were increased in naive and miR-340 in memory CD4(+) T cells from patients with multiple sclerosis, inhibiting Th2 cell development and favouring pro-inflammatory Th1 responses." tissue_expression_up hsa-mir-27b Multiple Sclerosis 22088562 "miR-128 and miR-27b were increased in naive and miR-340 in memory CD4(+) T cells from patients with multiple sclerosis, inhibiting Th2 cell development and favouring pro-inflammatory Th1 responses." tissue_expression_up hsa-mir-192 Barrett Esophagus 22094011 "We demonstrated unequivocal statistically significant upregulation of two microRNAs (miR-192, 196a) and downregulation of miR-203 and positive miR-196a correlation with progression from intestinal metaplasia to adenocarcinoma compared to normal individuals." tissue_expression_up hsa-mir-196a-1 Barrett Esophagus 22094011 "We demonstrated unequivocal statistically significant upregulation of two microRNAs (miR-192, 196a) and downregulation of miR-203 and positive miR-196a correlation with progression from intestinal metaplasia to adenocarcinoma compared to normal individuals." tissue_expression_up hsa-mir-196a-2 Barrett Esophagus 22094011 "We demonstrated unequivocal statistically significant upregulation of two microRNAs (miR-192, 196a) and downregulation of miR-203 and positive miR-196a correlation with progression from intestinal metaplasia to adenocarcinoma compared to normal individuals." tissue_expression_up hsa-mir-155 Breast Neoplasms 22105810 "The relative expression of miR-155 was significantly higher in breast cancer tissues than in corresponding nontumor tissues. High miR-155 expression was correlated with higher tumor grade, advanced tumor stage and lymph node metastasis (P=0.012, 0.001, and 0.003, respectively). Kaplan-Meier survival analysis indicated that the disease-free and overall survival rates of high miR-155 group were significantly lower than those of low miR-155 group (P=0.038 and 0.029, respectively). Multivariate analysis showed that high miR-155 expression was a poor prognostic factor (P=0.009). Furthermore, antisense targeting miR-155 could inhibit growth, induce cell arrest in G(0) /G(1) phase, enhance apoptosis, and increase radiosensitivity in breast cancer cells." tissue_expression_up hsa-let-7a Pancreatic Neoplasms 22108826 "These effects were associated with decreased expression of EZH2 and increased expression of a panel of tumor-suppressive microRNAs (miRNA), including let-7a, b, c, d, miR-26a, miR-101, miR-146a, andmiR-200b, c that are typically lost in pancreatic cancer." tissue_expression_up hsa-let-7b Pancreatic Neoplasms 22108826 "These effects were associated with decreased expression of EZH2 and increased expression of a panel of tumor-suppressive microRNAs (miRNA), including let-7a, b, c, d, miR-26a, miR-101, miR-146a, andmiR-200b, c that are typically lost in pancreatic cancer." tissue_expression_up hsa-let-7c Pancreatic Neoplasms 22108826 "These effects were associated with decreased expression of EZH2 and increased expression of a panel of tumor-suppressive microRNAs (miRNA), including let-7a, b, c, d, miR-26a, miR-101, miR-146a, andmiR-200b, c that are typically lost in pancreatic cancer." tissue_expression_up hsa-let-7d Pancreatic Neoplasms 22108826 "These effects were associated with decreased expression of EZH2 and increased expression of a panel of tumor-suppressive microRNAs (miRNA), including let-7a, b, c, d, miR-26a, miR-101, miR-146a, andmiR-200b, c that are typically lost in pancreatic cancer." tissue_expression_up hsa-mir-101 Pancreatic Neoplasms 22108826 "These effects were associated with decreased expression of EZH2 and increased expression of a panel of tumor-suppressive microRNAs (miRNA), including let-7a, b, c, d, miR-26a, miR-101, miR-146a, andmiR-200b, c that are typically lost in pancreatic cancer." tissue_expression_up hsa-mir-146a Pancreatic Neoplasms 22108826 "These effects were associated with decreased expression of EZH2 and increased expression of a panel of tumor-suppressive microRNAs (miRNA), including let-7a, b, c, d, miR-26a, miR-101, miR-146a, andmiR-200b, c that are typically lost in pancreatic cancer." tissue_expression_up hsa-mir-200b Pancreatic Neoplasms 22108826 "These effects were associated with decreased expression of EZH2 and increased expression of a panel of tumor-suppressive microRNAs (miRNA), including let-7a, b, c, d, miR-26a, miR-101, miR-146a, andmiR-200b, c that are typically lost in pancreatic cancer." tissue_expression_up hsa-mir-200c Pancreatic Neoplasms 22108826 "These effects were associated with decreased expression of EZH2 and increased expression of a panel of tumor-suppressive microRNAs (miRNA), including let-7a, b, c, d, miR-26a, miR-101, miR-146a, andmiR-200b, c that are typically lost in pancreatic cancer." tissue_expression_up hsa-mir-26a Pancreatic Neoplasms 22108826 "These effects were associated with decreased expression of EZH2 and increased expression of a panel of tumor-suppressive microRNAs (miRNA), including let-7a, b, c, d, miR-26a, miR-101, miR-146a, andmiR-200b, c that are typically lost in pancreatic cancer." tissue_expression_up hsa-mir-21 Pancreatic Neoplasms 22114136 "In the initial cohort of 48 PDAC (pancreatic ductal adenocarcinoma) patients, high expression of miR-21 (Hazard ratio (HR): 3.22, 95% Confidence Interval (CI):1.21-8.58) and reduced expression of miR-34a (HR 0.15, 95%CI: 0.06-0.37) and miR-30d (HR:0.30, 95%CI:0.12-0.79) were associated with poor overall survival following resection independent of clinical covariates. In a further validation set of 24 patients miR-21 and miR-34a expression again significantly correlated with overall survival (P = 0.031 and P = 0.001)." tissue_expression_up hsa-mir-122 Hepatitis C Virus Infection 22114337 "A high level of miR122 was expressed by lentiviral vector into human liver cell lines at a level comparable to the endogenous level in Huh7 cells. Among the cell lines we examined, Hep3B cells stably expressing miR122 (Hep3B/miR122) exhibited a significant enhancement of HCVcc propagation. Surprisingly, the productions of infectious particles in Hep3B/miR122 cells upon infection with HCVcc were comparable to those in Huh7 cells. Furthermore, a line of cured cells established by elimination of HCV RNA from the Hep3B/miR122 replicon cells exhibited an enhanced expression of miR122 and a continuous increase of infectious titers of HCVcc in every passage." tissue_expression_up hsa-mir-10b Pancreatic Neoplasms 22117151 "miR-10b is upregulated in pancreatic ductal adenocarcinoma and can be used as a diagnostic marker in endoscopic ultrasound-guided fine-needle aspiration biopsies of suspicious pancreatic lesions. In addition, miR-10b may be able to guide neoadjuvant gemcitabine-based chemoradiotherapy and predict metastatic-free survival and overall survival." tissue_expression_up hsa-mir-221 Prostate Neoplasms 22117988 "The level of ARHI mRNA was significantly lower in aggressive compared with non-aggressive prostate cancer tissue samples. In contrast, microRNA 221 and 222 levels were significantly higher in aggressive compared with non-aggressive prostate cancer tissue samples." tissue_expression_up hsa-mir-222 Prostate Neoplasms 22117988 "The level of ARHI mRNA was significantly lower in aggressive compared with non-aggressive prostate cancer tissue samples. In contrast, microRNA 221 and 222 levels were significantly higher in aggressive compared with non-aggressive prostate cancer tissue samples." tissue_expression_up hsa-let-7a-1 Colorectal Carcinoma 22120473 "Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases." tissue_expression_up hsa-let-7a-2 Colorectal Carcinoma 22120473 "Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases." tissue_expression_up hsa-let-7a-3 Colorectal Carcinoma 22120473 "Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases." tissue_expression_up hsa-mir-135a-1 Colorectal Carcinoma 22120473 "Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases." tissue_expression_up hsa-mir-135a-2 Colorectal Carcinoma 22120473 "Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases." tissue_expression_up hsa-mir-21 Colorectal Carcinoma 22120473 "Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases." tissue_expression_up hsa-mir-335 Colorectal Carcinoma 22120473 "Increased expression of miR-21, mir-135a and miR-335 was associated with clinical progression of CRC (colorectal cancer), while miR-206 demonstrated an opposite trend. The levels of mir-21 did not associate with the expression of PTEN, an important tumour suppressor in CRC and one of many putative targets of miR-21, but interestingly was associated with stage of disease in the PTEN expressing tumours. Surprisingly, let7a, a KRAS-targeting miR, showed elevated expression in metastatic disease compared to normal mucosa or non-metastatic disease, and only in KRAS mutation positive tumors. Finally, a prognostic signature of miR 21,135a, 335, 206 and let-7a for detecting the presence of metastases had a specificity of 87% and sensitivity of 76% for the presence of metastases." tissue_expression_up hsa-let-7a-1 Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-let-7a-2 Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-let-7a-3 Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-let-7c Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-130a Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-181b-1 Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-181b-2 Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-19b-1 Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-19b-2 Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-23a Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-301a Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-30a Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-520d Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-548a-1 Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-548a-2 Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-548a-3 Periodontitis 22128589 "Six miRNA genes, let-7a, let-7c, miR-130a, miR301a, miR-520d, and miR-548a, were up-regulated more than 8 fold compared to the healthy gingiva. miR-181b, miR-19b, miR-23a, miR-30a, miR-let7a, and miR-301a, were amplified successfully and increased much more in periodontitis gingivae than in healthy ones." tissue_expression_up hsa-mir-206 Muscular Dystrophy 22129894 The expression of miR-206 is increased in muscular dystrophy. tissue_expression_up hsa-mir-9-1 Melanoma 22131135 MicroRNA-9 up-regulates E-cadherin through inhibition of NF-kB1-Snail1 pathway in melanoma. tissue_expression_up hsa-mir-21 Urinary Bladder Cancer 22133680 Nuclear and cytoplasmatic PDCD4 immunostaining decreased significantly with histopathological progression of the tumor (p<0001). Controls showed strong nuclear and cytoplasmatic immunohistochemical staining. MiR-21 up regulation in tissue corresponded to PDCD4 suppression. tissue_expression_up hsa-mir-146a Lichen Planus 22139425 Increased miRNA-146a and miRNA-155 expressions in oral lichen planus. tissue_expression_up hsa-mir-155 Lichen Planus 22139425 Increased miRNA-146a and miRNA-155 expressions in oral lichen planus. tissue_expression_up hsa-mir-187 Gastric Neoplasms 22169097 "Genome-wide miRNA expression profiles followed with Real-Time quantitative RT-PCR (qRT-PCR) assays revealed that miR-187(*), miR-371-5p and miR-378 were significantly elevated in GC patients. Further validation indicated that miR-378 alone could yields a ROC curve area of 0.861 with 87.5% sensitivity and 70.73% specificity in discriminating GC patients from healthy controls." tissue_expression_up hsa-mir-371a Gastric Neoplasms 22169097 "Genome-wide miRNA expression profiles followed with Real-Time quantitative RT-PCR (qRT-PCR) assays revealed that miR-187(*), miR-371-5p and miR-378 were significantly elevated in GC patients. Further validation indicated that miR-378 alone could yields a ROC curve area of 0.861 with 87.5% sensitivity and 70.73% specificity in discriminating GC patients from healthy controls." tissue_expression_up hsa-mir-378a Gastric Neoplasms 22169097 "Genome-wide miRNA expression profiles followed with Real-Time quantitative RT-PCR (qRT-PCR) assays revealed that miR-187(*), miR-371-5p and miR-378 were significantly elevated in GC patients. Further validation indicated that miR-378 alone could yields a ROC curve area of 0.861 with 87.5% sensitivity and 70.73% specificity in discriminating GC patients from healthy controls." tissue_expression_up hsa-mir-375 "Carcinoma, Lung, Small-Cell" 22172490 miR-375 is highly expressed and possibly transactivated by achaete-scute complex homolog 1 in small-cell lung cancer cells. tissue_expression_up hsa-mir-1183 Rectal Neoplasms 22172905 "Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases." tissue_expression_up hsa-mir-1224 Rectal Neoplasms 22172905 "Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases." tissue_expression_up hsa-mir-125a Rectal Neoplasms 22172905 "Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases." tissue_expression_up hsa-mir-1471 Rectal Neoplasms 22172905 "Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases." tissue_expression_up hsa-mir-188 Rectal Neoplasms 22172905 "Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases." tissue_expression_up hsa-mir-1909 Rectal Neoplasms 22172905 "Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases." tissue_expression_up hsa-mir-483 Rectal Neoplasms 22172905 "Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases." tissue_expression_up hsa-mir-622 Rectal Neoplasms 22172905 "Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases." tissue_expression_up hsa-mir-630 Rectal Neoplasms 22172905 "Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases." tissue_expression_up hsa-mir-671 Rectal Neoplasms 22172905 "Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases." tissue_expression_up hsa-mir-765 Rectal Neoplasms 22172905 "Microarray analysis selected 14 miRNAs as being differentially expressed in TRG1 patients, and 13 were confirmed by qRT-PCR: 11 miRNAs (miR-1183, miR-483-5p, miR-622, miR-125a-3p, miR-1224-5p, miR-188-5p, miR-1471, miR-671-5p, miR-1909, miR-630, miR-765) were significantly upregulated in TRG1 patients, 2 (miR-1274b, miR-720) were downexpressed. MiR-622 and miR-630 had a 100% sensitivity and specificity in selecting TRG1 cases." tissue_expression_up hsa-mir-192 Colon Neoplasms 22180714 "Compared with expression in SW1116 cells, 35 miRNAs (including hsa-miR-192, hsa-miR-29b, hsa-miR-215, hsa-miR-194, hsa-miR-33a and hsa-miR-32) were upregulated more than 1.5-fold, and 11 miRNAs (including hsa-miR-93, hsa-miR-1231, hsa-miRPlus-F1080, hsa-miR-524-3p, hsa-miR-886-3p and hsa-miR-561) were downregulated in SW1116csc." tissue_expression_up hsa-mir-194 Colon Neoplasms 22180714 "Compared with expression in SW1116 cells, 35 miRNAs (including hsa-miR-192, hsa-miR-29b, hsa-miR-215, hsa-miR-194, hsa-miR-33a and hsa-miR-32) were upregulated more than 1.5-fold, and 11 miRNAs (including hsa-miR-93, hsa-miR-1231, hsa-miRPlus-F1080, hsa-miR-524-3p, hsa-miR-886-3p and hsa-miR-561) were downregulated in SW1116csc." tissue_expression_up hsa-mir-215 Colon Neoplasms 22180714 "Compared with expression in SW1116 cells, 35 miRNAs (including hsa-miR-192, hsa-miR-29b, hsa-miR-215, hsa-miR-194, hsa-miR-33a and hsa-miR-32) were upregulated more than 1.5-fold, and 11 miRNAs (including hsa-miR-93, hsa-miR-1231, hsa-miRPlus-F1080, hsa-miR-524-3p, hsa-miR-886-3p and hsa-miR-561) were downregulated in SW1116csc." tissue_expression_up hsa-mir-29b Colon Neoplasms 22180714 "Compared with expression in SW1116 cells, 35 miRNAs (including hsa-miR-192, hsa-miR-29b, hsa-miR-215, hsa-miR-194, hsa-miR-33a and hsa-miR-32) were upregulated more than 1.5-fold, and 11 miRNAs (including hsa-miR-93, hsa-miR-1231, hsa-miRPlus-F1080, hsa-miR-524-3p, hsa-miR-886-3p and hsa-miR-561) were downregulated in SW1116csc." tissue_expression_up hsa-mir-32 Colon Neoplasms 22180714 "Compared with expression in SW1116 cells, 35 miRNAs (including hsa-miR-192, hsa-miR-29b, hsa-miR-215, hsa-miR-194, hsa-miR-33a and hsa-miR-32) were upregulated more than 1.5-fold, and 11 miRNAs (including hsa-miR-93, hsa-miR-1231, hsa-miRPlus-F1080, hsa-miR-524-3p, hsa-miR-886-3p and hsa-miR-561) were downregulated in SW1116csc." tissue_expression_up hsa-mir-33a Colon Neoplasms 22180714 "Compared with expression in SW1116 cells, 35 miRNAs (including hsa-miR-192, hsa-miR-29b, hsa-miR-215, hsa-miR-194, hsa-miR-33a and hsa-miR-32) were upregulated more than 1.5-fold, and 11 miRNAs (including hsa-miR-93, hsa-miR-1231, hsa-miRPlus-F1080, hsa-miR-524-3p, hsa-miR-886-3p and hsa-miR-561) were downregulated in SW1116csc." tissue_expression_up hsa-mir-155 Down Syndrome 22182977 "a screening of micro-RNA (miRNA) from Down's syndrome brain and peripheral tissues indicated an upregulation of a chromosome 21-encoded miRNA-155 and a decrease in the abundance of the miRNA-155 mRNA target complement factor H (CFH), an important repressor of the innate immune response." tissue_expression_up hsa-mir-7-1 "Allergic Rhinitis,Perennial" 22185732 up-regulated tissue_expression_up hsa-mir-7-2 "Allergic Rhinitis,Perennial" 22185732 up-regulated tissue_expression_up hsa-mir-7-3 "Allergic Rhinitis,Perennial" 22185732 up-regulated tissue_expression_up hsa-mir-21 Urinary Bladder Cancer 22194833 mir-21 expression increased with worsening clinical diagnosis but that mir-143 was not correlated with histology. These observations were in stark contrast to previous reports involving cervical cancer cell lines in which mir-143 was consistently down-regulated but mir-21 largely unaffected. tissue_expression_up hsa-mir-192 Diabetic Nephropathy 22211842 "TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated." tissue_expression_up hsa-mir-21 Diabetic Nephropathy 22211842 "TGF-beta1 activates Smad3 to regulate microRNAs that mediate renal fibrosis. Of them, miR-21 and miR-192 are upregulated but miR-29 and miR-200 families are downregulated." tissue_expression_up hsa-mir-122 "Carcinoma, Hepatocellular" 22213236 up-regulated in HCC tissues.correlated with cirrhosis tissue_expression_up hsa-mir-21 "Carcinoma, Hepatocellular" 22213236 up-regulated in HCC tissues.correlated with cirrhosis;associated with tumor stage and poor prognosis. tissue_expression_up hsa-mir-221 "Carcinoma, Hepatocellular" 22213236 up-regulated in HCC tissues.correlated with cirrhosis;associated with tumor stage and poor prognosis. tissue_expression_up hsa-mir-222 "Carcinoma, Hepatocellular" 22213236 up-regulated in HCC tissues. tissue_expression_up hsa-mir-31 "Carcinoma, Hepatocellular" 22213236 up-regulated in HCC tissues.correlated with cirrhosis tissue_expression_up hsa-mir-155 Pancreatic Neoplasms 22213426 "We found over-expression of miR-21, miR-221, miR-27a, miR-27b, and miR-155, and down-regulation of miR-216a,miR-216b, miR-217, and miR-146a expression in tumors derived from KC and KCI mouse model" tissue_expression_up hsa-mir-21 Pancreatic Neoplasms 22213426 "We found over-expression of miR-21, miR-221, miR-27a, miR-27b, and miR-155, and down-regulation of miR-216a,miR-216b, miR-217, and miR-146a expression in tumors derived from KC and KCI mouse model" tissue_expression_up hsa-mir-221 Pancreatic Neoplasms 22213426 "We found over-expression of miR-21, miR-221, miR-27a, miR-27b, and miR-155, and down-regulation of miR-216a,miR-216b, miR-217, and miR-146a expression in tumors derived from KC and KCI mouse model" tissue_expression_up hsa-mir-27a Pancreatic Neoplasms 22213426 "We found over-expression of miR-21, miR-221, miR-27a, miR-27b, and miR-155, and down-regulation of miR-216a,miR-216b, miR-217, and miR-146a expression in tumors derived from KC and KCI mouse model" tissue_expression_up hsa-mir-27b Pancreatic Neoplasms 22213426 "We found over-expression of miR-21, miR-221, miR-27a, miR-27b, and miR-155, and down-regulation of miR-216a,miR-216b, miR-217, and miR-146a expression in tumors derived from KC and KCI mouse model" tissue_expression_up hsa-mir-483 "Diabetes Mellitus, Type 2" 22223106 "Increased miR-483-3p expression in vivo, programmed by early-life nutrition, limits storage of lipids in adipose tissue, causing lipotoxicity and insulin resistance and thus increasing susceptibility to metabolic disease." tissue_expression_up hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 22238073 SOCS1 is significantly up-regulated in Nutlin-3-treated p53(wild-type) B chronic lymphocytic leukemia (B-CLL) samples and shows an inverse correlation with miR-155. tissue_expression_up hsa-mir-107 Prostate Neoplasms 22240788 miR-107 and miR-574-3p were quantified at significantly higher concentrations in the urine of men with prostate cancer compared with controls. tissue_expression_up hsa-mir-574 Prostate Neoplasms 22240788 miR-107 and miR-574-3p were quantified at significantly higher concentrations in the urine of men with prostate cancer compared with controls. tissue_expression_up hsa-mir-101-1 Pheochromocytoma 22241719 "miR-483-5p, miR-183, and miR-101 had significantly higher expression in malignant tumors as compared to their benign counterparts." tissue_expression_up hsa-mir-101-2 Pheochromocytoma 22241719 "miR-483-5p, miR-183, and miR-101 had significantly higher expression in malignant tumors as compared to their benign counterparts." tissue_expression_up hsa-mir-183 Pheochromocytoma 22241719 "miR-483-5p, miR-183, and miR-101 had significantly higher expression in malignant tumors as compared to their benign counterparts." tissue_expression_up hsa-mir-483 Pheochromocytoma 22241719 "miR-483-5p, miR-183, and miR-101 had significantly higher expression in malignant tumors as compared to their benign counterparts." tissue_expression_up hsa-mir-221 Liver Cirrhosis 22267590 MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis. tissue_expression_up hsa-mir-222 Liver Cirrhosis 22267590 MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis. tissue_expression_up hsa-let-7a-1 Cholesteatoma 22289526 "Levels of miR-21 and let-7a microRNA were significantly higher in cholesteatoma tissue compared with normal skin, especially in paediatric patients." tissue_expression_up hsa-let-7a-2 Cholesteatoma 22289526 "Levels of miR-21 and let-7a microRNA were significantly higher in cholesteatoma tissue compared with normal skin, especially in paediatric patients." tissue_expression_up hsa-let-7a-3 Cholesteatoma 22289526 "Levels of miR-21 and let-7a microRNA were significantly higher in cholesteatoma tissue compared with normal skin, especially in paediatric patients." tissue_expression_up hsa-mir-21 Cholesteatoma 22289526 "Levels of miR-21 and let-7a microRNA were significantly higher in cholesteatoma tissue compared with normal skin, especially in paediatric patients." tissue_expression_up hsa-mir-21 Colorectal Carcinoma 22289545 There was a significantly higher level of miR-21 in CRC tumour tissue than in NAT and high expression of miR-21 was significantly correlated with advanced clinical stage and poor cell differentiation. tissue_expression_up hsa-mir-200a Breast Neoplasms 22294488 The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer. tissue_expression_up hsa-mir-200b Breast Neoplasms 22294488 The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer. tissue_expression_up hsa-mir-200c Breast Neoplasms 22294488 The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer. tissue_expression_up hsa-mir-9-1 Breast Neoplasms 22294488 The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer. tissue_expression_up hsa-mir-9-2 Breast Neoplasms 22294488 The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer. tissue_expression_up hsa-mir-9-3 Breast Neoplasms 22294488 The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer. tissue_expression_up hsa-mir-145 Prostate Neoplasms 22298119 Significantly increased miR-145 expression were observed for patients with intermediate or high risk D'Amico scores compared to patients with low risk scores tissue_expression_up hsa-mir-20a Prostate Neoplasms 22298119 miR-20a was significantly overexpressed in plasma from patients with stage 3 tumors compared to stage 2 or below (P=0.03). tissue_expression_up hsa-mir-21 Prostate Neoplasms 22298119 The expression levels for miR-20a and miR-21 were significantly increased in patients with high risk CAPRA scores tissue_expression_up hsa-mir-21 Laryngeal Neoplasms 22320969 "Mir-21 was up-regulated in LSCCs and HSCCs compared to adjacent non-tumor tissues (P < 0.05), and the up-regulated expression of mir-21 was associated with clinical stage (P = 0.001), T classification (P = 0.007), pathologic differentiation (P = 0.025), and lymph node positivity (P = 0.002)." tissue_expression_up hsa-mir-21 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 22320969 "Mir-21 was up-regulated in LSCCs (laryngeal squamous cell carcinomas) and HSCCs(hypopharyngeal squamous cell carcinomas) compared to adjacent non-tumor tissues (P < 0.05), and the up-regulated expression of mir-21 was associated with clinical stage (P = 0.001), T classification (P = 0.007), pathologic differentiation (P = 0.025), and lymph node positivity (P = 0.002)." tissue_expression_up hsa-mir-210 Breast Neoplasms 22323552 High Expression of MicroRNA-210 is an Independent Factor Indicating a Poor Prognosis in Japanese Triple-negative Breast Cancer Patients. tissue_expression_up hsa-mir-21 Breast Neoplasms 22323912 "High miR-21 expression was associated with mastectomy, larger tumor size, higher stage, higher grade, estrogen receptor (ER) negative, human epidermal growth factor receptor 2 (HER2) positive, HER2 positive breast cancer subtype, high Ki-67 expression, and death." tissue_expression_up hsa-mir-1-1 Myocardial Infarction 22330002 "MiR-1, -21 -133a and -423-5p showed a 3- to 10-fold increase and miR-499-5p exhibited >80-fold increase in acute NSTEMI patient vs. CTR." tissue_expression_up hsa-mir-1-2 Myocardial Infarction 22330002 "MiR-1, -21 -133a and -423-5p showed a 3- to 10-fold increase and miR-499-5p exhibited >80-fold increase in acute NSTEMI patient vs. CTR." tissue_expression_up hsa-mir-133a-1 Myocardial Infarction 22330002 "MiR-1, -21 -133a and -423-5p showed a 3- to 10-fold increase and miR-499-5p exhibited >80-fold increase in acute NSTEMI patient vs. CTR." tissue_expression_up hsa-mir-133a-2 Myocardial Infarction 22330002 "MiR-1, -21 -133a and -423-5p showed a 3- to 10-fold increase and miR-499-5p exhibited >80-fold increase in acute NSTEMI patient vs. CTR." tissue_expression_up hsa-mir-21 Myocardial Infarction 22330002 "MiR-1, -21 -133a and -423-5p showed a 3- to 10-fold increase and miR-499-5p exhibited >80-fold increase in acute NSTEMI patient vs. CTR." tissue_expression_up hsa-mir-423 Myocardial Infarction 22330002 "MiR-1, -21 -133a and -423-5p showed a 3- to 10-fold increase and miR-499-5p exhibited >80-fold increase in acute NSTEMI patient vs. CTR." tissue_expression_up hsa-mir-21 Glioma 22335906 miR-21 was up-regulated 1.49-fold in SHG-44(R) cells (Radioresistant cell line) relative to the SHG-44 cells. tissue_expression_up hsa-mir-34b Ovarian Neoplasms 22340095 "The expressions of miR-449a/b, miR-34b and miR-34c were 19-fold to 21-fold elevated after p53 activation by genotoxic agent adriamycin." tissue_expression_up hsa-mir-34c Ovarian Neoplasms 22340095 "The expressions of miR-449a/b, miR-34b and miR-34c were 19-fold to 21-fold elevated after p53 activation by genotoxic agent adriamycin." tissue_expression_up hsa-mir-449a Ovarian Neoplasms 22340095 "The expressions of miR-449a/b, miR-34b and miR-34c were 19-fold to 21-fold elevated after p53 activation by genotoxic agent adriamycin." tissue_expression_up hsa-mir-449b Ovarian Neoplasms 22340095 "The expressions of miR-449a/b, miR-34b and miR-34c were 19-fold to 21-fold elevated after p53 activation by genotoxic agent adriamycin." tissue_expression_up hsa-mir-182 "Lymphoma, Hodgkin" 22343918 "In cHL cell lines FOXO1 is inactivated by multiple mechanisms, including constitutive activation of AKT/PKB and MAPK/ERK kinases and up-regulation of microRNAs miR-96, miR-182, and miR-183." tissue_expression_up hsa-mir-183 "Lymphoma, Hodgkin" 22343918 "In cHL cell lines FOXO1 is inactivated by multiple mechanisms, including constitutive activation of AKT/PKB and MAPK/ERK kinases and up-regulation of microRNAs miR-96, miR-182, and miR-183." tissue_expression_up hsa-mir-96 "Lymphoma, Hodgkin" 22343918 "In cHL cell lines FOXO1 is inactivated by multiple mechanisms, including constitutive activation of AKT/PKB and MAPK/ERK kinases and up-regulation of microRNAs miR-96, miR-182, and miR-183." tissue_expression_up hsa-mir-148b Ovarian Neoplasms 22344713 "miR-148b was overexpressed in 92.21% (71/77) of the ovarian cancer samples examined, and overexpression of miR-148b in ovarian cancer tissues was not associated with any of the clinicopathological features of patients with ovarian cancer." tissue_expression_up hsa-mir-181a-1 Osteosarcoma 22350417 high expression tissue_expression_up hsa-mir-181a-2 Osteosarcoma 22350417 high expression tissue_expression_up hsa-mir-181b-1 Osteosarcoma 22350417 high expression tissue_expression_up hsa-mir-181b-2 Osteosarcoma 22350417 high expression tissue_expression_up hsa-mir-181c Osteosarcoma 22350417 high expression tissue_expression_up hsa-mir-125b-1 Glioma 22360855 "The levels of miRNA-125b and MMP9 were significantly higher in SU3 and SU2, also a highly invasive GSCPs we established before, than in U251s." tissue_expression_up hsa-mir-663a Burns 22360957 miR-663 was up-regulated in denatured dermis compared with those in normal skin. tissue_expression_up hsa-mir-206 Prolactinoma 22366961 miR-206 was significantly up-regulated in prolactinomas following bromocriptine treatment. tissue_expression_up hsa-mir-516b-1 Prolactinoma 22366961 miR-516b was significantly up-regulated in prolactinomas following bromocriptine treatment. tissue_expression_up hsa-mir-516b-2 Prolactinoma 22366961 miR-516b was significantly up-regulated in prolactinomas following bromocriptine treatment. tissue_expression_up hsa-mir-550a-1 Prolactinoma 22366961 miR-516b was significantly up-regulated in prolactinomas following bromocriptine treatment. tissue_expression_up hsa-mir-550a-2 Prolactinoma 22366961 miR-550 was significantly up-regulated in prolactinomas following bromocriptine treatment. tissue_expression_up hsa-mir-671 Prolactinoma 22366961 miR-671-5p was significantly up-regulated in prolactinomas following bromocriptine treatment. tissue_expression_up hsa-mir-21 Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_up hsa-mir-302a Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_up hsa-mir-302b Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_up hsa-mir-302c Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_up hsa-mir-302d Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_up hsa-mir-302e Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_up hsa-mir-302f Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_up hsa-mir-372 Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_up hsa-mir-373 Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_up hsa-mir-520c Gastric Neoplasms 22374783 "Real-time RT-PCR analysis demonstrated an increase in mir-21 and mir-302 expression level in CSCs(cancer stem cells), relative to cancer cells, whereas let-7a expression level was decreased in CSC in comparison with cancer cells. mir-372, mir-373 and mir-520c-5p were markedly increased in cancer cells in comparison with CSCs." tissue_expression_up hsa-mir-20a Glioma 22381757 The glioma tissues showed significantly up-regulated expression of miR-20a compared with normal brain tissues (P=0.035). The expression level of miR-20a was higher in high-grade than in low-grade gliomas. miR-20a mimics significantly enhanced the proliferation of U251 cells and the percentage of S-phase cells. tissue_expression_up hsa-mir-19b-1 Colon Neoplasms 22382630 "In response to 5-FU, miR-19b and miR-21 were over-expressed in 5-FU-resistant cells." tissue_expression_up hsa-mir-19b-2 Colon Neoplasms 22382630 "In response to 5-FU, miR-19b and miR-21 were over-expressed in 5-FU-resistant cells." tissue_expression_up hsa-mir-21 Colorectal Carcinoma 22382630 "In response to 5-FU, miR-19b and miR-21 were over-expressed in 5-FU-resistant cells." tissue_expression_up hsa-mir-199a-1 Chronic Obstructive Pulmonary Disease 22383663 "miR-34a and miR-199a-5p expression was increased and the phosphorylation of AKT was decreased in COPD lungs. The miR-199a-5p expression was correlated with HIF-1§Ø©ãprotein expression in COPD patient's lungs. Transfection of HPMVEC with the miR-199a-5p precursor gene decreased HIF-1§Ø©ãprotein expression, and transfection with the miR-34a precursor gene increased miR-199a-5p expression." tissue_expression_up hsa-mir-34a Chronic Obstructive Pulmonary Disease 22383663 "miR-34a and miR-199a-5p expression was increased and the phosphorylation of AKT was decreased in COPD lungs. The miR-199a-5p expression was correlated with HIF-1§Ø©ãprotein expression in COPD patient's lungs. Transfection of HPMVEC with the miR-199a-5p precursor gene decreased HIF-1§Ø©ãprotein expression, and transfection with the miR-34a precursor gene increased miR-199a-5p expression." tissue_expression_up hsa-mir-155 Urinary Bladder Cancer 22386240 "Compared with controls, the patients with bladder cancer had a lower expression of the miR-200 family, miR-192, and miR-155 in the urinary sediment; lower expression of miR-192; and higher expression of miR-155 in the urinary supernatant." tissue_expression_up hsa-mir-708 Bladder Neoplasms 22393979 Differential miRNA expression profiles in bladder urothelial carcinomas identified miR-100 down-regulation and miR-708 up-regulation among the most common alterations tissue_expression_up hsa-mir-126 Colorectal Carcinoma 22397399 The median miRNA-126 expression level was significantly higher in patients responding to XELOX (capecitabine and oxaliplatin). tissue_expression_up hsa-mir-638 Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_up hsa-mir-663a Breast Neoplasms 22403704 "Treatment with E2, BPA and DDT decreased (p<0.05) miR-21 expression. Several members of the let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e and let-7f), were downregulated (p<0.05) by all three treatments.and miR-15b (p<0.005) and miR-27b (p<0.01) were also downregulated by the three treatments.upregulation of miR-638 (P<0.005), miR-663 (P<0.005), and miR-1915 (P<0.005) was observed after treatment of MCF7 cells with E2, BPA or DDT" tissue_expression_up hsa-mir-107 Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-142 Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-150 Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-17 Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-191 Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-196a-1 Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-196a-2 Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-21 Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-26b Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-30b Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-9-1 Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-9-2 Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-9-3 Gastric Neoplasms 22407237 "In the analysis by real-time PCR-based miRNA arrays using pooled RNA samples from five gastric cancer patients, expression of miR-107, miR-21, miR-196a, miR-26b, miR-9, miR-142-3p, miR-30b, miR-150, miR-191 and miR-17 was found to be upregulation.miR-107 expression showed significant association with depth of tumor invasion, lymph node metastasis and stage. In Kaplan-Meier survival curve analysis, overall survival rates (OS) and disease-free survival rates (DFS) of patients with high miR-107 expression were significantly worse than those of patients with low miR-107 expression. In the Cox multivariate analysis, it was shown that miR-107 expression in gastric cancer tissues was an independent prognostic factor for OS and DFS. Significant inverse correlations were demonstrated between miR-107 and DICER1 mRNA. Our results indicate that miR-107 may be useful as an effective biomarker for prediction of a poor prognosis in gastric cancer patients." tissue_expression_up hsa-mir-155 Graft-Versus-Host Disease 22408260 miR-155 up-regulation was shown in specimens from patients with pathological evidence of intestinal aGVHD (Acute graft-versus-host disease). tissue_expression_up hsa-mir-26a-1 Multiple Endocrine Neoplasia Type 1 22409234 "The authors found that in hADSCs the siRNA-induced silencing of MEN1 mRNA resulted in a down regulation of miR-26a, with a consequent up-regulation of SMAD1 protein." tissue_expression_up hsa-mir-26a-2 Multiple Endocrine Neoplasia Type 1 22409234 "The authors found that in hADSCs the siRNA-induced silencing of MEN1 mRNA resulted in a down regulation of miR-26a, with a consequent up-regulation of SMAD1 protein." tissue_expression_up hsa-mir-21 Psoriasis 22417311 MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis. tissue_expression_up hsa-mir-196a-1 Gastric Neoplasms 22420029 "The expression level of miR-196a microRNA significantly increased in primary gastric cancer tissues versus adjacent normal tissues. In addition, extracellular miR-196a detected in conditioned medium was strongly correlated with its cellular expression status and increased circulating miR-196a in patient serum was associated with gastric cancer disease status and relapse." tissue_expression_up hsa-mir-196a-2 Gastric Neoplasms 22420029 "The expression level of miR-196a microRNA significantly increased in primary gastric cancer tissues versus adjacent normal tissues. In addition, extracellular miR-196a detected in conditioned medium was strongly correlated with its cellular expression status and increased circulating miR-196a in patient serum was associated with gastric cancer disease status and relapse." tissue_expression_up hsa-mir-130b Head And Neck Neoplasms 22425712 up-regulation tissue_expression_up hsa-mir-155 Head And Neck Neoplasms 22425712 up-regulation tissue_expression_up hsa-mir-21 Head And Neck Neoplasms 22425712 up-regulation tissue_expression_up hsa-mir-223 Head And Neck Neoplasms 22425712 up-regulation tissue_expression_up hsa-mir-31 Head And Neck Neoplasms 22425712 up-regulation tissue_expression_up hsa-mir-29a Colon Neoplasms 22426940 "High expression of miR-29a was associated with a longer disease-free survival (DFS) for patients with stage 2 colon cancer, on both univariate and multivariate analyses." tissue_expression_up hsa-mir-216a Heart Failure 22427379 "miR-216a was strongly increased in both D-HF (diabetic HF) and ND-HF (nondiabetic HF) patients, negatively correlated with left ventricular ejection fraction." tissue_expression_up hsa-mir-106a Gastric Neoplasms 22431000 miR-106a Is frequently upregulated in gastric cancer and inhibits the extrinsic apoptotic pathway by targeting FAS. tissue_expression_up hsa-mir-34a "Carcinoma, Lung, Non-Small-Cell" 22438124 Delta-tocotrienol suppresses Notch-1 pathway by up-regulating miR-34a in non-small cell lung cancer cells. tissue_expression_up hsa-mir-15a Leukemia 22449094 Pure curcumin decreases the expression of WT1 by upregulation of miR-15a and miR-16-1 in leukemic cells. tissue_expression_up hsa-mir-16-1 Leukemia 22449094 Pure curcumin decreases the expression of WT1 by upregulation of miR-15a and miR-16-1 in leukemic cells. tissue_expression_up hsa-mir-16-2 Leukemia 22449094 Pure curcumin decreases the expression of WT1 by upregulation of miR-15a and miR-16-1 in leukemic cells. tissue_expression_up hsa-mir-101-2 Gastric Neoplasms 22450781 Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 upregulation in intestinal gastric cancer. tissue_expression_up hsa-mir-100 Pancreatic Neoplasms 22466166 "Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions." tissue_expression_up hsa-mir-155 Pancreatic Neoplasms 22466166 "Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions." tissue_expression_up hsa-mir-181b-1 Pancreatic Neoplasms 22466166 "Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions." tissue_expression_up hsa-mir-181b-2 Pancreatic Neoplasms 22466166 "Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions." tissue_expression_up hsa-mir-196a-1 Pancreatic Neoplasms 22466166 "Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions." tissue_expression_up hsa-mir-196a-2 Pancreatic Neoplasms 22466166 "Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions." tissue_expression_up hsa-mir-21 Pancreatic Neoplasms 22466166 "Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions." tissue_expression_up hsa-mir-221 Pancreatic Neoplasms 22466166 "Carcinomas showed higher expression of miR-21, miR-221, miR-155, miR-100, and miR-181b than benign lesions. Cellblocks containing carcinoma showed higher expression of miR-21, miR-221, and miR-196a than those from benign lesions." tissue_expression_up hsa-mir-424 Urinary Bladder Cancer 22469983 Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancer. tissue_expression_up hsa-mir-21 Colorectal Carcinoma 22476768 Kaplan-Meier analysis proved that the miR-21 expression levels are correlated to shorter overall survival of CRC patients. tissue_expression_up hsa-mir-151a Breast Neoplasms 22489664 miR-151-5p upregulation may suppress metastasis in primary breast tumors. tissue_expression_up hsa-mir-151b Breast Neoplasms 22489664 miR-151-5p upregulation may suppress metastasis in primary breast tumors. tissue_expression_up hsa-mir-23b Prolactinoma 22490835 up-regulated tissue_expression_up hsa-mir-342 Prolactinoma 22490835 miR-342-3p: up-regulated tissue_expression_up hsa-mir-432 Prolactinoma 22490835 up-regulated tissue_expression_up hsa-mir-493 Prolactinoma 22490835 up-regulated tissue_expression_up hsa-mir-664 Prolactinoma 22490835 miR-664*: up-regulated tissue_expression_up hsa-mir-10b Breast Neoplasms 22492962 "The levels of miR-10b and miR-21 are found significantly increased in the CSF (cerebrospinal fluid) of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions." tissue_expression_up hsa-mir-10b Glioblastoma 22492962 "The levels of miR-10b and miR-21 are found significantly increased in the CSF (cerebrospinal fluid) of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions." tissue_expression_up hsa-mir-10b Lung Neoplasms 22492962 "The levels of miR-10b and miR-21 are found significantly increased in the CSF (cerebrospinal fluid) of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions." tissue_expression_up hsa-mir-21 Breast Neoplasms 22492962 "The levels of miR-10b and miR-21 are found significantly increased in the CSF (cerebrospinal fluid) of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions." tissue_expression_up hsa-mir-21 Glioblastoma 22492962 "The levels of miR-10b and miR-21 are found significantly increased in the CSF (cerebrospinal fluid) of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions." tissue_expression_up hsa-mir-21 Lung Neoplasms 22492962 "The levels of miR-10b and miR-21 are found significantly increased in the CSF (cerebrospinal fluid) of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions." tissue_expression_up hsa-mir-34a Neuroblastoma 22498172 "Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells)" tissue_expression_up hsa-mir-7-1 Neuroblastoma 22498172 "Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells)" tissue_expression_up hsa-mir-99a Neuroblastoma 22498172 "Combination of 4-HPR (N-(4-hydroxyphenyl) retinamide) and EGCG ((-)-epigallocatechin-3-gallate) most significantly decreased expression of OGmiRs (miR-92, miR-93, and miR-106b) and increased expression of TSmiRs (miR-7-1, miR-34a, and miR-99a) in both cell lines(SK-N-BE2 and IMR-32 cells)" tissue_expression_up hsa-mir-146a Osteoarthritis 22507670 "IL-1¦Â responsive miR-146a is overexpressed in an experimentally induced OA model, accompanied by upregulation of VEGF and downregulation of Smad4 in vivo." tissue_expression_up hsa-mir-200c Endometrial Neoplasms 22514717 The expression levels of miR-200c (P<0.0001) and miR-205 (P<0.0001) were significantly increased in endometrial tumors compared to normal tissues. Kaplan-Meier survival analysis revealed that high levels of miR-205 expression were associated with poor patient overall survival. tissue_expression_up hsa-mir-205 Endometrial Neoplasms 22514717 The expression levels of miR-200c (P<0.0001) and miR-205 (P<0.0001) were significantly increased in endometrial tumors compared to normal tissues. Kaplan-Meier survival analysis revealed that high levels of miR-205 expression were associated with poor patient overall survival. tissue_expression_up hsa-mir-155 Demyelinating Diseases 22517757 "Both in vivo and in vitro, myelin antigen stimulation resulted in significant up-regulation of miR-301a, miR-21, and miR-155." tissue_expression_up hsa-mir-21 Demyelinating Diseases 22517757 "Both in vivo and in vitro, myelin antigen stimulation resulted in significant up-regulation of miR-301a, miR-21, and miR-155." tissue_expression_up hsa-mir-132 "Liver Diseases, Alcoholic" 22518321 "In this paper, we summarize the current knowledge of miRNAs in ALD and also report increased expression of miR-155 and miR-132 in the total liver as well as in isolated hepatocytes and KCs of alcohol-fed mice." tissue_expression_up hsa-mir-155 "Liver Diseases, Alcoholic" 22518321 "In this paper, we summarize the current knowledge of miRNAs in ALD and also report increased expression of miR-155 and miR-132 in the total liver as well as in isolated hepatocytes and KCs of alcohol-fed mice." tissue_expression_up hsa-mir-125b-1 Breast Neoplasms 22523546 "miR-125b was significantly associated with therapeutic response, exhibiting higher expression level in non-responsive patients." tissue_expression_up hsa-mir-125b-2 Breast Neoplasms 22523546 "miR-125b was significantly associated with therapeutic response, exhibiting higher expression level in non-responsive patients." tissue_expression_up hsa-mir-10a Breast Neoplasms 22524830 "The BC patients showed an up-regulation in miRNAs (mir-155, mir-10,mir-21 and mir-373)" tissue_expression_up hsa-mir-10b Breast Neoplasms 22524830 "The BC patients showed an up-regulation in miRNAs (mir-155, mir-10,mir-21 and mir-373)" tissue_expression_up hsa-mir-155 Breast Neoplasms 22524830 "The BC patients showed an up-regulation in miRNAs (mir-155, mir-10,mir-21 and mir-373)" tissue_expression_up hsa-mir-21 Breast Neoplasms 22524830 "The BC patients showed an up-regulation in miRNAs (mir-155, mir-10,mir-21 and mir-373)" tissue_expression_up hsa-mir-373 Breast Neoplasms 22524830 "The BC patients showed an up-regulation in miRNAs (mir-155, mir-10,mir-21 and mir-373)" tissue_expression_up hsa-mir-155 Endometrial Neoplasms 22525818 miR-155 was over-expressed and AGTR1 was underexpressed in endometrial carcinoma tissues. tissue_expression_up hsa-mir-106b "Carcinoma, Basal Cell" 22540308 upregulated in the tumor center tissue_expression_up hsa-mir-125a "Carcinoma, Basal Cell" 22540308 miR-125a-5p is upregulated in the tumor center tissue_expression_up hsa-mir-17 "Carcinoma, Basal Cell" 22540308 upregulated in the tumor center tissue_expression_up hsa-mir-181c "Carcinoma, Basal Cell" 22540308 miR-181c and miR-181c* are upregulated in the tumor center tissue_expression_up hsa-mir-181d "Carcinoma, Basal Cell" 22540308 upregulated in the tumor center tissue_expression_up hsa-mir-182 "Carcinoma, Basal Cell" 22540308 upregulated in the tumor center tissue_expression_up hsa-mir-18a "Carcinoma, Basal Cell" 22540308 upregulated in the tumor center tissue_expression_up hsa-mir-18b "Carcinoma, Basal Cell" 22540308 upregulated in the tumor center tissue_expression_up hsa-mir-19b-1 "Carcinoma, Basal Cell" 22540308 miR-19b is upregulated in the tumor center tissue_expression_up hsa-mir-19b-2 "Carcinoma, Basal Cell" 22540308 miR-19b is upregulated in the tumor center tissue_expression_up hsa-mir-455 "Carcinoma, Basal Cell" 22540308 miR-455-5p and miR-455-3p are upregulated in the tumor center tissue_expression_up hsa-mir-542 "Carcinoma, Basal Cell" 22540308 miR-542 is upregulated in the tumor center tissue_expression_up hsa-mir-93 "Carcinoma, Basal Cell" 22540308 upregulated in the tumor center tissue_expression_up hsa-mir-30b "Squamous Cell Carcinoma, Oral" 22542163 Amplification and up-regulation of microRNA-30b in oral squamous cell cancers. tissue_expression_up hsa-mir-142 Endometrial Neoplasms 22543862 miR-142-5p: Increased expression after Progesterone Treatment. tissue_expression_up hsa-mir-146b Endometrial Neoplasms 22543862 miR-146b-5p: Increased expression after Progesterone Treatment. tissue_expression_up hsa-mir-21 Endometrial Neoplasms 22543862 Increased expression after Progesterone Treatment. tissue_expression_up hsa-mir-625 Endometrial Neoplasms 22543862 miR-625*: Increased expression after Progesterone Treatment. tissue_expression_up hsa-mir-34a Colorectal Carcinoma 22562822 "microRNA-34a, microRNA-155 and microRNA-200c overexpression in human colorectal cancer." tissue_expression_up hsa-mir-93 Gastric Neoplasms 22567743 "miR-93 is highly elevated in gastric cancer, especially in advanced and metastasized gastric cancer, suggesting miR-93 may play critical roles in carcinogenesis of gastric cancer. Overexpression of miR-93 can serve as a novel prognostic marker for gastric cancer." tissue_expression_up hsa-mir-708 "Carcinoma, Lung, Non-Small-Cell" 22573352 Increased miR-708 expression in NSCLC and its association with poor survival in lung adenocarcinoma from never smokers. tissue_expression_up hsa-mir-17 "Carcinoma, Hepatocellular" 22583011 miR-17-5p was significantly upregulated in HCCs. HCC with metastasis had higher miR-17-5p levels than that without metastasis. tissue_expression_up hsa-mir-142 Atopic Dermatitis 22594804 "In humans sensitized with DPCP, we found significant upregulation of miR-21, miR-142-3p, miR-142-5p and miR-223 in challenged skin." tissue_expression_up hsa-mir-21 Atopic Dermatitis 22594804 "In humans sensitized with DPCP, we found significant upregulation of miR-21, miR-142-3p, miR-142-5p and miR-223 in challenged skin." tissue_expression_up hsa-mir-223 Atopic Dermatitis 22594804 "In humans sensitized with DPCP, we found significant upregulation of miR-21, miR-142-3p, miR-142-5p and miR-223 in challenged skin." tissue_expression_up hsa-mir-150 Inflammation 22595106 "Of the 335 human miRNAs identified in the pulp tissues, 3 miRNAs, miR-150, miR-584, and miR-766, were significantly up-regulated in inflamed pulps as compared with normal pulps" tissue_expression_up hsa-mir-584 Inflammation 22595106 "Of the 335 human miRNAs identified in the pulp tissues, 3 miRNAs, miR-150, miR-584, and miR-766, were significantly up-regulated in inflamed pulps as compared with normal pulps" tissue_expression_up hsa-mir-766 Inflammation 22595106 "Of the 335 human miRNAs identified in the pulp tissues, 3 miRNAs, miR-150, miR-584, and miR-766, were significantly up-regulated in inflamed pulps as compared with normal pulps" tissue_expression_up hsa-mir-205 Laryngeal Neoplasms 22605671 Upregulation tissue_expression_up hsa-mir-21 Laryngeal Neoplasms 22605671 Upregulation tissue_expression_up hsa-mir-708 Laryngeal Neoplasms 22605671 Upregulation tissue_expression_up hsa-mir-93 Laryngeal Neoplasms 22605671 Upregulation tissue_expression_up hsa-mir-221 Gastric Neoplasms 22613407 "MiR-221 was up-regulated in 88% (81/92) of gastric cancer tissue samples compared with their paired adjacent nontumour tissue samples. High expression of miR-221 showed a significant correlation with advanced tumour-node-metastasis stage, local invasion and lymphatic metastasis." tissue_expression_up hsa-mir-130a Ovarian Neoplasms 22614869 Altered microRNA expression in cisplatin-resistant ovarian cancer cells and upregulation of miR-130a associated with MDR1/P-glycoprotein-mediated drug resistance. tissue_expression_up hsa-mir-155 "Carcinoma, Hepatocellular" 22629365 "High expression levels of miR-155, miR-15a, miR-432, miR-486-3p, miR-15b and miR-30b were significantly associated with recurrence-free." tissue_expression_up hsa-mir-15a "Carcinoma, Hepatocellular" 22629365 "High expression levels of miR-155, miR-15a, miR-432, miR-486-3p, miR-15b and miR-30b were significantly associated with recurrence-free." tissue_expression_up hsa-mir-15b "Carcinoma, Hepatocellular" 22629365 "High expression levels of miR-155, miR-15a, miR-432, miR-486-3p, miR-15b and miR-30b were significantly associated with recurrence-free." tissue_expression_up hsa-mir-30b "Carcinoma, Hepatocellular" 22629365 "High expression levels of miR-155, miR-15a, miR-432, miR-486-3p, miR-15b and miR-30b were significantly associated with recurrence-free." tissue_expression_up hsa-mir-432 "Carcinoma, Hepatocellular" 22629365 "High expression levels of miR-155, miR-15a, miR-432, miR-486-3p, miR-15b and miR-30b were significantly associated with recurrence-free." tissue_expression_up hsa-mir-486 "Carcinoma, Hepatocellular" 22629365 "High expression levels of miR-155, miR-15a, miR-432, miR-486-3p, miR-15b and miR-30b were significantly associated with recurrence-free." tissue_expression_up hsa-mir-34a Head And Neck Neoplasms 22629428 Dysregulation of microRNA-34a expression in head and neck squamous cell carcinoma promotes tumor growth and tumor angiogenesis. tissue_expression_up hsa-mir-21 Breast Neoplasms 22638884 "miR-21 was significantly overexpressed in human solid cancerous serum relative to normal control (P < 0.001), and its sensitivity and specificity were significantly higher than the currently used tumor markers." tissue_expression_up hsa-mir-21 Colorectal Carcinoma 22638884 "miR-21 was significantly overexpressed in human solid cancerous serum relative to normal control (P < 0.001), and its sensitivity and specificity were significantly higher than the currently used tumor markers." tissue_expression_up hsa-mir-21 Esophageal Neoplasms 22638884 "miR-21 was significantly overexpressed in human solid cancerous serum relative to normal control (P < 0.001), and its sensitivity and specificity were significantly higher than the currently used tumor markers." tissue_expression_up hsa-mir-21 Gastric Neoplasms 22638884 "miR-21 was significantly overexpressed in human solid cancerous serum relative to normal control (P < 0.001), and its sensitivity and specificity were significantly higher than the currently used tumor markers." tissue_expression_up hsa-mir-21 Lung Neoplasms 22638884 "miR-21 was significantly overexpressed in human solid cancerous serum relative to normal control (P < 0.001), and its sensitivity and specificity were significantly higher than the currently used tumor markers." tissue_expression_up hsa-mir-181a-2 Colorectal Carcinoma 22641662 "KRAS up-regulates the expression of miR-181a, miR-200c and miR-210 in a three-dimensional-specific manner in DLD-1 colorectal cancer cells." tissue_expression_up hsa-mir-200c Colorectal Carcinoma 22641662 "KRAS up-regulates the expression of miR-181a, miR-200c and miR-210 in a three-dimensional-specific manner in DLD-1 colorectal cancer cells." tissue_expression_up hsa-mir-210 Colorectal Carcinoma 22641662 "KRAS up-regulates the expression of miR-181a, miR-200c and miR-210 in a three-dimensional-specific manner in DLD-1 colorectal cancer cells." tissue_expression_up hsa-mir-146a Ovarian Neoplasms 22643117 "We found 37 differentially expressed miRNAs in the CD133(+) spheroid-forming subpopulation of OVCAR3 cells, 34 of which were significantly up-regulated, including miR-205, miR-146a, miR-200a, miR-200b, and miR-3, and 3 of which were significantly down-regulated, including miR-1202 and miR-1181." tissue_expression_up hsa-mir-200a Ovarian Neoplasms 22643117 "We found 37 differentially expressed miRNAs in the CD133(+) spheroid-forming subpopulation of OVCAR3 cells, 34 of which were significantly up-regulated, including miR-205, miR-146a, miR-200a, miR-200b, and miR-3, and 3 of which were significantly down-regulated, including miR-1202 and miR-1181." tissue_expression_up hsa-mir-200b Ovarian Neoplasms 22643117 "We found 37 differentially expressed miRNAs in the CD133(+) spheroid-forming subpopulation of OVCAR3 cells, 34 of which were significantly up-regulated, including miR-205, miR-146a, miR-200a, miR-200b, and miR-3, and 3 of which were significantly down-regulated, including miR-1202 and miR-1181." tissue_expression_up hsa-mir-205 Ovarian Neoplasms 22643117 "We found 37 differentially expressed miRNAs in the CD133(+) spheroid-forming subpopulation of OVCAR3 cells, 34 of which were significantly up-regulated, including miR-205, miR-146a, miR-200a, miR-200b, and miR-3, and 3 of which were significantly down-regulated, including miR-1202 and miR-1181." tissue_expression_up hsa-mir-3 Ovarian Neoplasms 22643117 "We found 37 differentially expressed miRNAs in the CD133(+) spheroid-forming subpopulation of OVCAR3 cells, 34 of which were significantly up-regulated, including miR-205, miR-146a, miR-200a, miR-200b, and miR-3, and 3 of which were significantly down-regulated, including miR-1202 and miR-1181." tissue_expression_up hsa-mir-335 Glioma 22644918 Tumor microRNA-335 expression is associated with poor prognosis in human glioma. tissue_expression_up hsa-mir-92a-1 "Scleroderma, Systemic" 22661558 microRNA-92a expression in the sera and dermal fibroblasts increases in patients with scleroderma. tissue_expression_up hsa-mir-92a-2 "Scleroderma, Systemic" 22661558 microRNA-92a expression in the sera and dermal fibroblasts increases in patients with scleroderma. tissue_expression_up hsa-mir-182 Lung Neoplasms 22672859 "Four up-regulated microRNAs (miR-210, miR-21, miR-31 and miR-182) and two down-regulated mcroiRNAs (miR-126 and miR-145) were consistently reported both in squamous carcinoma and adenocarcinoma-based subgroup analysis" tissue_expression_up hsa-mir-21 Lung Neoplasms 22672859 "Four up-regulated microRNAs (miR-210, miR-21, miR-31 and miR-182) and two down-regulated mcroiRNAs (miR-126 and miR-145) were consistently reported both in squamous carcinoma and adenocarcinoma-based subgroup analysis" tissue_expression_up hsa-mir-210 Lung Neoplasms 22672859 "Four up-regulated microRNAs (miR-210, miR-21, miR-31 and miR-182) and two down-regulated mcroiRNAs (miR-126 and miR-145) were consistently reported both in squamous carcinoma and adenocarcinoma-based subgroup analysis" tissue_expression_up hsa-mir-31 Lung Neoplasms 22672859 "Four up-regulated microRNAs (miR-210, miR-21, miR-31 and miR-182) and two down-regulated mcroiRNAs (miR-126 and miR-145) were consistently reported both in squamous carcinoma and adenocarcinoma-based subgroup analysis" tissue_expression_up hsa-mir-190a Meningioma 22674195 Downregulation of miR-29c-3p and miR-219-5p were found to be associated with advanced clinical stages of meningioma. Kaplan-Meier analysis showed that high expression of miR-190a and low expression of miR-29c-3p and miR-219-5p correlated significantly with higher recurrence rates in meningioma patients. tissue_expression_up hsa-mir-221 Glioma 22681957 High level of miR-221/222 confers increased cell invasion and poor prognosis in glioma. tissue_expression_up hsa-mir-222 Glioma 22681957 High level of miR-221/222 confers increased cell invasion and poor prognosis in glioma. tissue_expression_up hsa-mir-17 Osteosarcoma 22682620 up-regulated in osteosarcoma. tissue_expression_up hsa-mir-18a Osteosarcoma 22682620 up-regulated in osteosarcoma. tissue_expression_up hsa-mir-19a Osteosarcoma 22682620 up-regulated in osteosarcoma. tissue_expression_up hsa-mir-19b-1 Osteosarcoma 22682620 up-regulated in osteosarcoma. tissue_expression_up hsa-mir-20a Osteosarcoma 22682620 up-regulated in osteosarcoma. tissue_expression_up hsa-mir-92a-1 Osteosarcoma 22682620 up-regulated in osteosarcoma. tissue_expression_up hsa-mir-134 Pancreatic Neoplasms 22690071 "miR-95, miR-134 and miR-34c-3p are the top three miRNAs regulated by glargine (3.65-fold, 2.67-fold and 2.60-fold changes respectively, P < 0.01) in Sw1990 cells." tissue_expression_up hsa-mir-34c Pancreatic Neoplasms 22690071 "miR-95, miR-134 and miR-34c-3p are the top three miRNAs regulated by glargine (3.65-fold, 2.67-fold and 2.60-fold changes respectively, P < 0.01) in Sw1990 cells." tissue_expression_up hsa-mir-95 Pancreatic Neoplasms 22690071 "miR-95, miR-134 and miR-34c-3p are the top three miRNAs regulated by glargine (3.65-fold, 2.67-fold and 2.60-fold changes respectively, P < 0.01) in Sw1990 cells." tissue_expression_up hsa-mir-21 Urinary Bladder Cancer 22704449 High miR-21 expression correlated with worse overall patient survival (p = 0.0099). tissue_expression_up hsa-mir-21 Melanoma 22716245 microRNA-21 is upregulated in malignant melanoma and influences apoptosis of melanocytic cells. tissue_expression_up hsa-mir-301a Prostate Neoplasms 22719071 upregulated in prostate cancer stem/progenitor cell. tissue_expression_up hsa-mir-301b Prostate Neoplasms 22719071 upregulated in prostate cancer stem/progenitor cell. tissue_expression_up hsa-mir-452 Prostate Neoplasms 22719071 upregulated in prostate cancer stem/progenitor cell. tissue_expression_up hsa-mir-137 Glioblastoma 22722712 "miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract)." tissue_expression_up hsa-mir-145 Glioblastoma 22722712 "miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract)." tissue_expression_up hsa-mir-153-1 Glioblastoma 22722712 "miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract)." tissue_expression_up hsa-mir-153-2 Glioblastoma 22722712 "miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract)." tissue_expression_up hsa-mir-181b-1 Glioblastoma 22722712 "miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract)." tissue_expression_up hsa-mir-181b-2 Glioblastoma 22722712 "miR-181b, miR-153, miR-145, miR-137, and let-7d were significantly upregulated after treatment with both TMZ (temozolomide ) and OLE (Olea europaea leaf extract)." tissue_expression_up hsa-mir-1 Heart Failure 22735911 "Some miRNAs highly expressed in the heart, such as miR-1,miR-133 and miR-208, are strongly associated with the development of cardiac hypertrophy, while the exact role of miR-21 in the cardiovascular system remains controversial." tissue_expression_up hsa-mir-133 Heart Failure 22735911 "Some miRNAs highly expressed in the heart, such as miR-1,miR-133 and miR-208, are strongly associated with the development of cardiac hypertrophy, while the exact role of miR-21 in the cardiovascular system remains controversial." tissue_expression_up hsa-mir-208 Heart Failure 22735911 "Some miRNAs highly expressed in the heart, such as miR-1,miR-133 and miR-208, are strongly associated with the development of cardiac hypertrophy, while the exact role of miR-21 in the cardiovascular system remains controversial." tissue_expression_up hsa-mir-21 Heart Failure 22735911 "Some miRNAs highly expressed in the heart, such as miR-1,miR-133 and miR-208, are strongly associated with the development of cardiac hypertrophy, while the exact role of miR-21 in the cardiovascular system remains controversial." tissue_expression_up hsa-mir-21 Multiple Myeloma 22739167 "It is concluded that the expression levels of miR-21 in BMMNC of MM patients are significantly higher than in normal bone marrow, these data indicated that miR-21 may play an important role in the development of MM." tissue_expression_up hsa-mir-10b Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-125b Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-126 Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-133a Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-133b Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-143 Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-145 Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-146a Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-199a Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-199b Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-22 Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-28 Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-576 Colorectal Carcinoma 22740910 "Overexpression of miR-145, miR-1, miR-146a, miR-576-5p, miR-126*, HS287, miR-28-5p, miR-143, miR-199b-5p, miR-199a-5p, miR-10b, miR-22, miR-133b, miR-145*, miR-199a, miR-133a, miR-125b and downregulation of miR-31 and HS170 were observed in brain-metastatic carcinomas." tissue_expression_up hsa-mir-127 Thyroid Neoplasms 22747440 "MTC and CCH were both characterized by a significant overexpression of the whole set of miRNAs (the increase being 4.2-fold for miR-21, 6.7-fold for miR-127, 8.8-fold for miR-154, 6.6-fold for miR-224, 5.8-fold for miR-323, 6.1-fold for miR-370, 13-fold for miR-9*, 6.7-fold for miR-183, and 10.1 for miR-375, p<0.0001)." tissue_expression_up hsa-mir-154 Thyroid Neoplasms 22747440 "MTC and CCH were both characterized by a significant overexpression of the whole set of miRNAs (the increase being 4.2-fold for miR-21, 6.7-fold for miR-127, 8.8-fold for miR-154, 6.6-fold for miR-224, 5.8-fold for miR-323, 6.1-fold for miR-370, 13-fold for miR-9*, 6.7-fold for miR-183, and 10.1 for miR-375, p<0.0001)." tissue_expression_up hsa-mir-183 Thyroid Neoplasms 22747440 "MTC and CCH were both characterized by a significant overexpression of the whole set of miRNAs (the increase being 4.2-fold for miR-21, 6.7-fold for miR-127, 8.8-fold for miR-154, 6.6-fold for miR-224, 5.8-fold for miR-323, 6.1-fold for miR-370, 13-fold for miR-9*, 6.7-fold for miR-183, and 10.1 for miR-375, p<0.0001)." tissue_expression_up hsa-mir-21 Thyroid Neoplasms 22747440 "MTC and CCH were both characterized by a significant overexpression of the whole set of miRNAs (the increase being 4.2-fold for miR-21, 6.7-fold for miR-127, 8.8-fold for miR-154, 6.6-fold for miR-224, 5.8-fold for miR-323, 6.1-fold for miR-370, 13-fold for miR-9*, 6.7-fold for miR-183, and 10.1 for miR-375, p<0.0001)." tissue_expression_up hsa-mir-224 Thyroid Neoplasms 22747440 "MTC and CCH were both characterized by a significant overexpression of the whole set of miRNAs (the increase being 4.2-fold for miR-21, 6.7-fold for miR-127, 8.8-fold for miR-154, 6.6-fold for miR-224, 5.8-fold for miR-323, 6.1-fold for miR-370, 13-fold for miR-9*, 6.7-fold for miR-183, and 10.1 for miR-375, p<0.0001)." tissue_expression_up hsa-mir-323 Thyroid Neoplasms 22747440 "MTC and CCH were both characterized by a significant overexpression of the whole set of miRNAs (the increase being 4.2-fold for miR-21, 6.7-fold for miR-127, 8.8-fold for miR-154, 6.6-fold for miR-224, 5.8-fold for miR-323, 6.1-fold for miR-370, 13-fold for miR-9*, 6.7-fold for miR-183, and 10.1 for miR-375, p<0.0001)." tissue_expression_up hsa-mir-370 Thyroid Neoplasms 22747440 "MTC and CCH were both characterized by a significant overexpression of the whole set of miRNAs (the increase being 4.2-fold for miR-21, 6.7-fold for miR-127, 8.8-fold for miR-154, 6.6-fold for miR-224, 5.8-fold for miR-323, 6.1-fold for miR-370, 13-fold for miR-9*, 6.7-fold for miR-183, and 10.1 for miR-375, p<0.0001)." tissue_expression_up hsa-mir-375 Thyroid Neoplasms 22747440 "MTC and CCH were both characterized by a significant overexpression of the whole set of miRNAs (the increase being 4.2-fold for miR-21, 6.7-fold for miR-127, 8.8-fold for miR-154, 6.6-fold for miR-224, 5.8-fold for miR-323, 6.1-fold for miR-370, 13-fold for miR-9*, 6.7-fold for miR-183, and 10.1 for miR-375, p<0.0001)." tissue_expression_up hsa-mir-9 Thyroid Neoplasms 22747440 "MTC and CCH were both characterized by a significant overexpression of the whole set of miRNAs (the increase being 4.2-fold for miR-21, 6.7-fold for miR-127, 8.8-fold for miR-154, 6.6-fold for miR-224, 5.8-fold for miR-323, 6.1-fold for miR-370, 13-fold for miR-9*, 6.7-fold for miR-183, and 10.1 for miR-375, p<0.0001)." tissue_expression_up hsa-mir-125b-2 Myotonic Muscular Dystrophy 22768114 miR-125b-5p: decreased levels compared to controls tissue_expression_up hsa-mir-146b Myotonic Muscular Dystrophy 22768114 higher levels compared to controls tissue_expression_up hsa-mir-208a Myotonic Muscular Dystrophy 22768114 miR-146b-5p: higher levels compared to controls tissue_expression_up hsa-mir-221 Myotonic Muscular Dystrophy 22768114 higher levels compared to controls tissue_expression_up hsa-mir-34a Myotonic Muscular Dystrophy 22768114 miR-34a-5p: higher levels compared to controls tissue_expression_up hsa-mir-34b Myotonic Muscular Dystrophy 22768114 miR-34b-3p: higher levels compared to controls tissue_expression_up hsa-mir-34c Myotonic Muscular Dystrophy 22768114 miR-34c-5p: higher levels compared to controls tissue_expression_up hsa-mir-381 Myotonic Muscular Dystrophy 22768114 higher levels compared to controls tissue_expression_up hsa-mir-92a-1 Colorectal Carcinoma 22772712 Overexpression of miR-92a correlates with tumor metastasis and poor prognosis in patients with colorectal cancer. tissue_expression_up hsa-mir-668 Interstitial Lung Disease 22782705 upregulated tissue_expression_up hsa-mir-92b Interstitial Lung Disease 22782705 upregulated tissue_expression_up hsa-mir-15a Ischemia-Reperfusion Injury 22783320 MicroRNA-15a/b are up-regulated in response to myocardial ischemia/reperfusion injury. tissue_expression_up hsa-mir-15a Myocardial Ischemic-Reperfusion Injury 22783320 MicroRNA-15a/b are up-regulated in response to myocardial ischemia/reperfusion injury. tissue_expression_up hsa-mir-15b Ischemia-Reperfusion Injury 22783320 MicroRNA-15a/b are up-regulated in response to myocardial ischemia/reperfusion injury. tissue_expression_up hsa-mir-15b Myocardial Ischemic-Reperfusion Injury 22783320 MicroRNA-15a/b are up-regulated in response to myocardial ischemia/reperfusion injury. tissue_expression_up hsa-mir-182 Glioma 22788545 "The concentration of miRNA-182 in glioma patients was found to be 3.1 times as high as that in healthy persons, a conclusion in excellent agreement with a separate qPCR measurement of the expression level." tissue_expression_up hsa-mir-21 Head And Neck Neoplasms 22811001 "The expression level of miR-21 was significantly up-regulated in plasma samples obtained from HNSCC patients (p<0.01) than those from healthy subjects, which were in consistent with our finding in HNSCC tissues." tissue_expression_up hsa-mir-142 Eosinophilic Esophagitis 22815788 "Compared to the post-glucocorticoid treated esophageal mucosa,MiR-214, miR-146b-5b, 146a, 145, 142-3p and 21 were upregulated." tissue_expression_up hsa-mir-145 Eosinophilic Esophagitis 22815788 "Compared to the post-glucocorticoid treated esophageal mucosa,MiR-214, miR-146b-5b, 146a, 145, 142-3p and 21 were upregulated." tissue_expression_up hsa-mir-146a Eosinophilic Esophagitis 22815788 "Compared to the post-glucocorticoid treated esophageal mucosa,MiR-214, miR-146b-5b, 146a, 145, 142-3p and 21 were upregulated." tissue_expression_up hsa-mir-146b Eosinophilic Esophagitis 22815788 "Compared to the post-glucocorticoid treated esophageal mucosa,MiR-214, miR-146b-5b, 146a, 145, 142-3p and 21 were upregulated." tissue_expression_up hsa-mir-21 Eosinophilic Esophagitis 22815788 "Compared to the post-glucocorticoid treated esophageal mucosa,MiR-214, miR-146b-5b, 146a, 145, 142-3p and 21 were upregulated." tissue_expression_up hsa-mir-106b Glioma 22825541 Upregulation of miR-20a and miR-106b is involved in the acquisition of malignancy of pediatric brainstem gliomas. tissue_expression_up hsa-mir-20a Glioma 22825541 Upregulation of miR-20a and miR-106b is involved in the acquisition of malignancy of pediatric brainstem gliomas. tissue_expression_up hsa-mir-146a Nasopharyngeal Neoplasms 22843060 Expression of miRNA-146a in nasopharyngeal carcinoma is upregulated by Epstein-Barr virus latent membrane protein 1. tissue_expression_up hsa-mir-214 Liver Cirrhosis 22849305 miR-214-5p was upregulated in human and mouse livers in a fibrosis progression-dependent manner. tissue_expression_up hsa-mir-155 Pancreatic Neoplasms 22850622 "miR-21, miR-155, miR-210, miR-221, and miR-222, were overexpressed in diseased tissues than in the control samples, whereas miR-31, miR-122, miR-145, and miR-146a were underexpressed." tissue_expression_up hsa-mir-21 Pancreatic Neoplasms 22850622 "miR-21, miR-155, miR-210, miR-221, and miR-222, were overexpressed in diseased tissues than in the control samples, whereas miR-31, miR-122, miR-145, and miR-146a were underexpressed." tissue_expression_up hsa-mir-210 Pancreatic Neoplasms 22850622 "miR-21, miR-155, miR-210, miR-221, and miR-222, were overexpressed in diseased tissues than in the control samples, whereas miR-31, miR-122, miR-145, and miR-146a were underexpressed." tissue_expression_up hsa-mir-222 Pancreatic Neoplasms 22850622 "miR-21, miR-155, miR-210, miR-221, and miR-222, were overexpressed in diseased tissues than in the control samples, whereas miR-31, miR-122, miR-145, and miR-146a were underexpressed." tissue_expression_up hsa-mir-208b Heart Failure 22859947 "Increasing doses of doxorubicin, but not etoposide (a Topoisomerase II inhibitor devoid of cardiovascular toxicity), specifically induced the up-regulation of miR-208b, miR-216b, miR-215, miR-34c and miR-367 in rat hearts. " tissue_expression_up hsa-mir-215 Heart Failure 22859947 "Increasing doses of doxorubicin, but not etoposide (a Topoisomerase II inhibitor devoid of cardiovascular toxicity), specifically induced the up-regulation of miR-208b, miR-216b, miR-215, miR-34c and miR-367 in rat hearts. " tissue_expression_up hsa-mir-216b Heart Failure 22859947 "Increasing doses of doxorubicin, but not etoposide (a Topoisomerase II inhibitor devoid of cardiovascular toxicity), specifically induced the up-regulation of miR-208b, miR-216b, miR-215, miR-34c and miR-367 in rat hearts. " tissue_expression_up hsa-mir-34c Heart Failure 22859947 "Increasing doses of doxorubicin, but not etoposide (a Topoisomerase II inhibitor devoid of cardiovascular toxicity), specifically induced the up-regulation of miR-208b, miR-216b, miR-215, miR-34c and miR-367 in rat hearts. " tissue_expression_up hsa-mir-367 Heart Failure 22859947 "Increasing doses of doxorubicin, but not etoposide (a Topoisomerase II inhibitor devoid of cardiovascular toxicity), specifically induced the up-regulation of miR-208b, miR-216b, miR-215, miR-34c and miR-367 in rat hearts. " tissue_expression_up hsa-mir-141 Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-200a Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-200c Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-29c Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-378a Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-378b Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-378c Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-378d-1 Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-378d-2 Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-378e Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-378f Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-378g Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-378h Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-378i Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-429 Urinary Bladder Cancer 22886973 "hsa-mir-29c, hsa-miR-200a, hsa-miR-378, hsa-miR-429, hsa-miR-200c and hsa-miR-141 were up-regulated, while hsa-miR-451 was down-regulated." tissue_expression_up hsa-mir-221 Asthma 22895815 Upregulation of miRNA-221 and miRNA-485-3p in pediatric asthma. tissue_expression_up hsa-mir-485 Asthma 22895815 Upregulation of miRNA-221 and miRNA-485-3p in pediatric asthma. tissue_expression_up hsa-mir-1225 Melanoma 22898827 "we assayed the MITF-KD miRNA profiles using a miRNA microarray and found that hsa-miR-1225-3p, hsa-miR-634, hsa-miR-197, hsa-miR-766, hsa-miR-574-5p and hsa-miR-328 were upregulated, and hsa-miR-720 and hsa-miR-1308 were downregulated in MITF knocked down melanocytes." tissue_expression_up hsa-mir-197 Melanoma 22898827 "we assayed the MITF-KD miRNA profiles using a miRNA microarray and found that hsa-miR-1225-3p, hsa-miR-634, hsa-miR-197, hsa-miR-766, hsa-miR-574-5p and hsa-miR-328 were upregulated, and hsa-miR-720 and hsa-miR-1308 were downregulated in MITF knocked down melanocytes." tissue_expression_up hsa-mir-328 Melanoma 22898827 "we assayed the MITF-KD miRNA profiles using a miRNA microarray and found that hsa-miR-1225-3p, hsa-miR-634, hsa-miR-197, hsa-miR-766, hsa-miR-574-5p and hsa-miR-328 were upregulated, and hsa-miR-720 and hsa-miR-1308 were downregulated in MITF knocked down melanocytes." tissue_expression_up hsa-mir-574 Melanoma 22898827 "we assayed the MITF-KD miRNA profiles using a miRNA microarray and found that hsa-miR-1225-3p, hsa-miR-634, hsa-miR-197, hsa-miR-766, hsa-miR-574-5p and hsa-miR-328 were upregulated, and hsa-miR-720 and hsa-miR-1308 were downregulated in MITF knocked down melanocytes." tissue_expression_up hsa-mir-634 Melanoma 22898827 "we assayed the MITF-KD miRNA profiles using a miRNA microarray and found that hsa-miR-1225-3p, hsa-miR-634, hsa-miR-197, hsa-miR-766, hsa-miR-574-5p and hsa-miR-328 were upregulated, and hsa-miR-720 and hsa-miR-1308 were downregulated in MITF knocked down melanocytes." tissue_expression_up hsa-mir-766 Melanoma 22898827 "we assayed the MITF-KD miRNA profiles using a miRNA microarray and found that hsa-miR-1225-3p, hsa-miR-634, hsa-miR-197, hsa-miR-766, hsa-miR-574-5p and hsa-miR-328 were upregulated, and hsa-miR-720 and hsa-miR-1308 were downregulated in MITF knocked down melanocytes." tissue_expression_up hsa-mir-128a Colon Neoplasms 22898888 "in colonic fibroblasts p38 was only moderately activated, p53 as well as p16 expressions were upregulated in the presence of increased expression of miR-34a, miR-128a and miR-449a." tissue_expression_up hsa-mir-34a Colon Neoplasms 22898888 "in colonic fibroblasts p38 was only moderately activated, p53 as well as p16 expressions were upregulated in the presence of increased expression of miR-34a, miR-128a and miR-449a." tissue_expression_up hsa-mir-449a Colon Neoplasms 22898888 "in colonic fibroblasts p38 was only moderately activated, p53 as well as p16 expressions were upregulated in the presence of increased expression of miR-34a, miR-128a and miR-449a." tissue_expression_up hsa-mir-147a "Tuberculosis, Pulmonary" 22900099 Overexpression tissue_expression_up hsa-mir-147b "Tuberculosis, Pulmonary" 22900099 Overexpression tissue_expression_up hsa-mir-3179-1 "Tuberculosis, Pulmonary" 22900099 Overexpression tissue_expression_up hsa-mir-3179-2 "Tuberculosis, Pulmonary" 22900099 Overexpression tissue_expression_up hsa-mir-3179-3 "Tuberculosis, Pulmonary" 22900099 Overexpression tissue_expression_up hsa-mir-181b-1 Gastric Neoplasms 22901205 The upregulation of miR-181b may play an important role in the progress of gastric cancer and miR-181b maybe a potential molecular target for anticancer therapeutics of gastric cancer. tissue_expression_up hsa-mir-181b-2 Gastric Neoplasms 22901205 The upregulation of miR-181b may play an important role in the progress of gastric cancer and miR-181b maybe a potential molecular target for anticancer therapeutics of gastric cancer. tissue_expression_up hsa-mir-200b Endometrial Neoplasms 22904162 miR-200b and -210 were significantly up-regulated in the cancerous endometrium. tissue_expression_up hsa-mir-210 Endometrial Neoplasms 22904162 miR-200b and -210 were significantly up-regulated in the cancerous endometrium. tissue_expression_up hsa-mir-10b Pancreatic Neoplasms 22910491 MicroRNA-10b is overexpressed in pancreatic cancer. tissue_expression_up hsa-mir-155 "Carcinoma, Neuroendocrine" 22924844 The expression levels of miR-21 and miR-155 were significantly higher in high-grade NE carcinomas (LCNECs and SCLCs) than in carcinoid tumors (TCs and ACs) (each P < 0.001). The expression level of miR-21 in carcinoid tumors with lymph node metastasis was significantly higher than in carcinoid tumors without lymph node metastasis (P= 0.010). tissue_expression_up hsa-mir-21 "Carcinoma, Neuroendocrine" 22924844 The expression levels of miR-21 and miR-155 were significantly higher in high-grade NE carcinomas (LCNECs and SCLCs) than in carcinoid tumors (TCs and ACs) (each P < 0.001). The expression level of miR-21 in carcinoid tumors with lymph node metastasis was significantly higher than in carcinoid tumors without lymph node metastasis (P= 0.010). tissue_expression_up hsa-mir-451a Pancreatic Neoplasms 22929886 "The expression of let-7c, let-7f, and miR-200c were significantly reduced in most patients whereas the expression of miR-486-5p and miR-451 were significantly elevated in all pancreas cancer patients." tissue_expression_up hsa-mir-451b Pancreatic Neoplasms 22929886 "The expression of let-7c, let-7f, and miR-200c were significantly reduced in most patients whereas the expression of miR-486-5p and miR-451 were significantly elevated in all pancreas cancer patients." tissue_expression_up hsa-mir-486 Pancreatic Neoplasms 22929886 "The expression of let-7c, let-7f, and miR-200c were significantly reduced in most patients whereas the expression of miR-486-5p and miR-451 were significantly elevated in all pancreas cancer patients." tissue_expression_up hsa-mir-135b Esophageal Neoplasms 22939244 Patients with high levels of miR-135b or miR-145 in the posttreatment biopsy specimens had significantly shorter median disease-free survival (DFS) than did those with low levels. tissue_expression_up hsa-mir-16-1 Acute Lung Injury 22940131 "miR-16 upregulates ENaC, a major sodium channel involved in resolution of pulmonary edema in acute lung injury." tissue_expression_up hsa-mir-16-2 Acute Lung Injury 22940131 "miR-16 upregulates ENaC, a major sodium channel involved in resolution of pulmonary edema in acute lung injury." tissue_expression_up hsa-mir-142 Atrial Fibrillation 22944230 "MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation." tissue_expression_up hsa-mir-146b Atrial Fibrillation 22944230 "MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation." tissue_expression_up hsa-mir-155 Atrial Fibrillation 22944230 "MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation." tissue_expression_up hsa-mir-193b Atrial Fibrillation 22944230 "MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation." tissue_expression_up hsa-mir-19a Atrial Fibrillation 22944230 "MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation." tissue_expression_up hsa-mir-19b-1 Atrial Fibrillation 22944230 "MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation." tissue_expression_up hsa-mir-19b-2 Atrial Fibrillation 22944230 "MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation." tissue_expression_up hsa-mir-223 Atrial Fibrillation 22944230 "MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation." tissue_expression_up hsa-mir-486 Atrial Fibrillation 22944230 "MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation." tissue_expression_up hsa-mir-519b Atrial Fibrillation 22944230 "MiR-155, miR-142-3p, miR-19b, miR-223, miR-146b-5p, miR-486-5p, miR-301b, miR-193b, miR-519b were found to be up-regulated by > 2 folds whereas miR-193a-5p was down-regulated in left atrial appendage (LAA) in patients with atrial fibrillation." tissue_expression_up hsa-mir-221 Breast Neoplasms 22964023 "We identified 11 dysregulated miRNAs in CAFs: three were up-regulated (miR-221-5p, miR-31-3p, miR-221-3p), while eight were down-regulated (miR-205, miR-200b, miR-200c, miR-141, miR-101,miR-342-3p, let-7g, miR-26b)" tissue_expression_up hsa-mir-31 Breast Neoplasms 22964023 "We identified 11 dysregulated miRNAs in CAFs: three were up-regulated (miR-221-5p, miR-31-3p, miR-221-3p), while eight were down-regulated (miR-205, miR-200b, miR-200c, miR-141, miR-101,miR-342-3p, let-7g, miR-26b)" tissue_expression_up hsa-mir-424 Tuberculosis 22964481 "we observed that miR-146a expression is also down-regulated in tuberculosis patients, both in PBMCs and PFMCs while miR-424 levels are elevated only in the peripheral compartments." tissue_expression_up hsa-let-7b Prion Diseases 22965126 "we show that exosomes released by prion-infected neuronal cells have increased let-7b, let-7i, miR-128a, miR-21, miR-222, miR-29b,miR-342-3p and miR-424 levels with decreased miR-146 a levels compared to non-infected exosomes." tissue_expression_up hsa-let-7i Prion Diseases 22965126 "we show that exosomes released by prion-infected neuronal cells have increased let-7b, let-7i, miR-128a, miR-21, miR-222, miR-29b,miR-342-3p and miR-424 levels with decreased miR-146 a levels compared to non-infected exosomes." tissue_expression_up hsa-mir-128a Prion Diseases 22965126 "we show that exosomes released by prion-infected neuronal cells have increased let-7b, let-7i, miR-128a, miR-21, miR-222, miR-29b,miR-342-3p and miR-424 levels with decreased miR-146 a levels compared to non-infected exosomes." tissue_expression_up hsa-mir-21 Prion Diseases 22965126 "we show that exosomes released by prion-infected neuronal cells have increased let-7b, let-7i, miR-128a, miR-21, miR-222, miR-29b,miR-342-3p and miR-424 levels with decreased miR-146 a levels compared to non-infected exosomes." tissue_expression_up hsa-mir-222 Prion Diseases 22965126 "we show that exosomes released by prion-infected neuronal cells have increased let-7b, let-7i, miR-128a, miR-21, miR-222, miR-29b,miR-342-3p and miR-424 levels with decreased miR-146 a levels compared to non-infected exosomes." tissue_expression_up hsa-mir-29b Prion Diseases 22965126 "we show that exosomes released by prion-infected neuronal cells have increased let-7b, let-7i, miR-128a, miR-21, miR-222, miR-29b,miR-342-3p and miR-424 levels with decreased miR-146 a levels compared to non-infected exosomes." tissue_expression_up hsa-mir-342 Prion Diseases 22965126 "we show that exosomes released by prion-infected neuronal cells have increased let-7b, let-7i, miR-128a, miR-21, miR-222, miR-29b,miR-342-3p and miR-424 levels with decreased miR-146 a levels compared to non-infected exosomes." tissue_expression_up hsa-mir-424 Prion Diseases 22965126 "we show that exosomes released by prion-infected neuronal cells have increased let-7b, let-7i, miR-128a, miR-21, miR-222, miR-29b,miR-342-3p and miR-424 levels with decreased miR-146 a levels compared to non-infected exosomes." tissue_expression_up hsa-mir-107 "Leukemia, Promyelocytic, Acute" 22967415 "The expression level of miR-15b, miR-16, miR-107, miR-223 and miR-342 in APL CR group were significantly upregulated compared with that of newly diagnosed APL groups (P < 0.05), while the expression level of miR-181a was significantly downregulated (P < 0.05)." tissue_expression_up hsa-mir-15b "Leukemia, Promyelocytic, Acute" 22967415 "The expression level of miR-15b, miR-16, miR-107, miR-223 and miR-342 in APL CR group were significantly upregulated compared with that of newly diagnosed APL groups (P < 0.05), while the expression level of miR-181a was significantly downregulated (P < 0.05)." tissue_expression_up hsa-mir-16 "Leukemia, Promyelocytic, Acute" 22967415 "The expression level of miR-15b, miR-16, miR-107, miR-223 and miR-342 in APL CR group were significantly upregulated compared with that of newly diagnosed APL groups (P < 0.05), while the expression level of miR-181a was significantly downregulated (P < 0.05)." tissue_expression_up hsa-mir-223 "Leukemia, Promyelocytic, Acute" 22967415 "The expression level of miR-15b, miR-16, miR-107, miR-223 and miR-342 in APL CR group were significantly upregulated compared with that of newly diagnosed APL groups (P < 0.05), while the expression level of miR-181a was significantly downregulated (P < 0.05)." tissue_expression_up hsa-mir-342 "Leukemia, Promyelocytic, Acute" 22967415 "The expression level of miR-15b, miR-16, miR-107, miR-223 and miR-342 in APL CR group were significantly upregulated compared with that of newly diagnosed APL groups (P < 0.05), while the expression level of miR-181a was significantly downregulated (P < 0.05)." tissue_expression_up hsa-mir-103 Gastrointestinal Neoplasms 22996433 "The high expression of miR-20a, miR-25, miR-93, miR-103, miR-106a, miR-106b, miR-130 was associated with lymph node metastasis" tissue_expression_up hsa-mir-106a Gastrointestinal Neoplasms 22996433 "The high expression of miR-20a, miR-25, miR-93, miR-103, miR-106a, miR-106b, miR-130 was associated with lymph node metastasis" tissue_expression_up hsa-mir-106b Gastrointestinal Neoplasms 22996433 "The high expression of miR-20a, miR-25, miR-93, miR-103, miR-106a, miR-106b, miR-130 was associated with lymph node metastasis" tissue_expression_up hsa-mir-130 Gastrointestinal Neoplasms 22996433 "The high expression of miR-20a, miR-25, miR-93, miR-103, miR-106a, miR-106b, miR-130 was associated with lymph node metastasis" tissue_expression_up hsa-mir-20a Gastrointestinal Neoplasms 22996433 "The high expression of miR-20a, miR-25, miR-93, miR-103, miR-106a, miR-106b, miR-130 was associated with lymph node metastasis" tissue_expression_up hsa-mir-221 Gastrointestinal Neoplasms 22996433 "The high expression of miR-222 and miR-221 showed correlation with shorter metastasis-free survival (P?=?0.039 and 0.033,respectively), and miR-222 high expression was related to reduced overall survival (P?=?0.012)." tissue_expression_up hsa-mir-222 Gastrointestinal Neoplasms 22996433 "The high expression of miR-222 and miR-221 showed correlation with shorter metastasis-free survival (P?=?0.039 and 0.033,respectively), and miR-222 high expression was related to reduced overall survival (P?=?0.012)." tissue_expression_up hsa-mir-25 Gastrointestinal Neoplasms 22996433 "The high expression of miR-20a, miR-25, miR-93, miR-103, miR-106a, miR-106b, miR-130 was associated with lymph node metastasis" tissue_expression_up hsa-mir-93 Gastrointestinal Neoplasms 22996433 "The high expression of miR-20a, miR-25, miR-93, miR-103, miR-106a, miR-106b, miR-130 was associated with lymph node metastasis" tissue_expression_up hsa-mir-21 Cervical Neoplasms 22997891 "The high expression of miR-21 in cervical cancer and Hela cell indicate that it may play a possible role of oncogenes, while miR-143 and miR-373 with low expression may play the role of tumor suppressor genes." tissue_expression_up hsa-mir-10a Prostate Neoplasms 22999546 "miR-100 and miR-10a showed under expression and over expression, respectively, in low grade pTa tumors." tissue_expression_up hsa-mir-135b "Squamous Cell Carcinoma, Skin or Unspecific" 23026055 "Non-stringent filtering with a non-adjusted p ¡Ü 0.01 revealed three up-regulated (hsa-miR-135b, hsa-miR-424 and hsa-miR-766) and six down-regulated (hsa-miR-30a*, hsa-miR-378, hsa-miR-145, hsa-miR-140-3p, hsa-miR-30a and hsa-miR-26a) miRNAs in cSCC" tissue_expression_up hsa-mir-424 "Squamous Cell Carcinoma, Skin or Unspecific" 23026055 "Non-stringent filtering with a non-adjusted p ¡Ü 0.01 revealed three up-regulated (hsa-miR-135b, hsa-miR-424 and hsa-miR-766) and six down-regulated (hsa-miR-30a*, hsa-miR-378, hsa-miR-145, hsa-miR-140-3p, hsa-miR-30a and hsa-miR-26a) miRNAs in cSCC" tissue_expression_up hsa-mir-766 "Squamous Cell Carcinoma, Skin or Unspecific" 23026055 "Non-stringent filtering with a non-adjusted p ¡Ü 0.01 revealed three up-regulated (hsa-miR-135b, hsa-miR-424 and hsa-miR-766) and six down-regulated (hsa-miR-30a*, hsa-miR-378, hsa-miR-145, hsa-miR-140-3p, hsa-miR-30a and hsa-miR-26a) miRNAs in cSCC" tissue_expression_up hsa-mir-372 Seminoma 23064661 "Hsa-mir-372 was upregulated around 1,270-fold (95?% confidence interval (CI) 525.2-3,064.8; sp?=?8.1e-5 by Mann-Whitney U test)" tissue_expression_up hsa-mir-217 "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_up hsa-mir-512 "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_up hsa-mir-517c "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_up hsa-mir-518a "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_up hsa-mir-518b "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_up hsa-mir-518e "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_up hsa-mir-519a "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_up hsa-mir-520g "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_up hsa-mir-522 "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_up hsa-mir-525 "Carcinoma, Hepatocellular" 23082062 "Ten up-regulated miRNAs (miR-217, miR-518b, miR-517c, miR-520g, miR-519a, miR-522, miR-518e, miR-525-3p, miR-512-3p, and miR-518a-3p) and 11 down-regulated miRNAs (miR-138, miR-214, miR-214#, miR-199a-5p, miR-433, miR-511, miR-592, miR-483-3p, miR-483-5p, miR-708 and miR-1275) were identified by Taqman miRNAs array and confirmed quantitatively by reverse transcription polymerase chain reaction in HCC and adjacent non-tumor tissues. " tissue_expression_up hsa-mir-106 Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_up hsa-mir-106b Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_up hsa-mir-10b Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_up hsa-mir-151 Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_up hsa-mir-192 Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_up hsa-mir-194 Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_up hsa-mir-21 Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_up hsa-mir-25 Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_up hsa-mir-93 Esophageal Neoplasms 23092349 "A number of consistently dysregulated miRNAs have been identified in EAC and/or ESCC, including upregulation of miR-21, miR-192, miR-194, miR-106-25 polycistron (miR-25, miR-93, and miR-106b), miR-10b, miR-151, and miR-93, and downregulation of miR-375, miR-203, miR-205, miR-145, miR- 27b,miR-100, miR-125b, let-7c, etc. " tissue_expression_up hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 23099007 High expression of miR-21 and miR-155 predicts recurrence and unfavourable survival in non-small cell lung cancer. tissue_expression_up hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 23099007 High expression of miR-21 and miR-155 predicts recurrence and unfavourable survival in non-small cell lung cancer. tissue_expression_up hsa-mir-1260 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-1274a Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-1274b Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-130b Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-146b Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-22 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-223 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-301a Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-3663 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-4281 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-4286 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-484 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-663 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-720 Melanoma 23111773 "In addition to several miRNAs previously known to be associated with CMM, 19 unidentified miRNA candidates were found to be dysregulated in CMM patient samples. Among the 19 novel miRNA candidates, the genes hsa-miR-22, hsa-miR-130b, hsa-miR-146b-5p,hsa-miR-223, hsa-miR-301a, hsa-miR-484, hsa-miR-663, hsa-miR-720, hsa-miR-1260,hsa-miR-1274a, hsa-miR-1274b, hsa-miR-3663-3p, hsa-miR-4281, and hsa-miR-4286 were upregulated, and the genes hsa-miR-24-1*, hsa-miR-26a, hsa-miR-4291, hsa-miR-4317, and hsa-miR-4324 were downregulated." tissue_expression_up hsa-mir-125b-1 Myocardial Ischemic-Reperfusion Injury 23123599 SR-A deficiency reduces myocardial ischemia/reperfusion injury; involvement of increased microRNA-125b expression in macrophages tissue_expression_up hsa-mir-125b-2 Myocardial Ischemic-Reperfusion Injury 23123599 SR-A deficiency reduces myocardial ischemia/reperfusion injury; involvement of increased microRNA-125b expression in macrophages tissue_expression_up hsa-mir-138 Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_up hsa-mir-146b Bladder Neoplasms 23169479 "Except for two miRNAs, miR-146b and miR-9, which were specifically upregulated in MIBC, the majority of miRNAs (n = 13) were deregulated in the same way in the two types of bladder tumors" tissue_expression_up hsa-mir-182 Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_up hsa-mir-200b Bladder Neoplasms 23169479 "three miRNAs were upregulated (miR-200b, miR-182 and miR-138) and the other 10 miRNAs were downregulated (miR-1, miR-133a, miR-133b, miR-145, miR-143, miR-204, miR-921, miR-1281, miR-199a and miR-199b)" tissue_expression_up hsa-mir-9 Bladder Neoplasms 23169479 "Except for two miRNAs, miR-146b and miR-9, which were specifically upregulated in MIBC, the majority of miRNAs (n = 13) were deregulated in the same way in the two types of bladder tumors" tissue_expression_up hsa-mir-155 Ovarian Neoplasms 23171795 "We found that in ovarian CAFs, miR-31 and miR-214 were downregulated, whereas miR-155 was upregulated when compared with normal or tumor-adjacent fibroblasts." tissue_expression_up hsa-mir-200c Breast Neoplasms 23185507 miR-200c targets a NF-kB up-regulated TrkB/NTF3 autocrine signaling loop to enhance anoikis sensitivity in triple negative breast cancer tissue_expression_up hsa-mir-205 "Carcinoma, Lung, Non-Small-Cell" 23207443 SQCC was distinguished from normal tissue and ADC by high-level miR-205 expression and decreased miR-26b. tissue_expression_up hsa-mir-122 Hepatitis B Virus Infection 23221562 HBV mRNAs-mediated miR-122 inhibition up-regulates PTTG1-binding protein which promotes HCC tumor growth and cell invasion tissue_expression_up hsa-mir-17 Glioma 23226946 Increased Expression of microRNA-17 Predicts Poor Prognosis in Human Glioma tissue_expression_up hsa-mir-18a Colon Neoplasms 23229340 MicroRNA-18a upregulates autophagy and ataxia telangiectasia mutated gene expression in HCT116 colon cancer cells tissue_expression_up hsa-mir-155 Ovarian Neoplasms 23230184 They found that decreased miR-31 and miR-214 and increased miR-155 expression can reprogram normal fibroblasts into tumor-promoting cancer-associated fibroblasts. tissue_expression_up hsa-mir-181a-2 Breast Neoplasms 23241956 TGF-beta upregulates miR-181a expression to promote breast cancer metastasis tissue_expression_up hsa-mir-182 Ovarian Neoplasms 23262295 The upregulation of signal transducer and activator of transcription 5-dependent microRNA-182 and microRNA-96 promotes ovarian cancer cell proliferation by targeting forkhead box O3 upon leptin stimulation tissue_expression_up hsa-mir-96 Ovarian Neoplasms 23262295 The upregulation of signal transducer and activator of transcription 5-dependent microRNA-182 and microRNA-96 promotes ovarian cancer cell proliferation by targeting forkhead box O3 upon leptin stimulation tissue_expression_up hsa-mir-183 Glioma 23263745 MicroRNA-183 upregulates HIF-1a by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells tissue_expression_up hsa-mir-224 Glioma 23263909 Upregulation of microRNA-224 confers a poor prognosis in glioma patients tissue_expression_up hsa-mir-103 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-1233 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-130b Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-135b Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-141 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-15a Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-182 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-183 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-18a Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-190 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-191 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-200b Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-21 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-422b Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-425 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-449b Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-601 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-639 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-644 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-649 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-93 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-96 Bladder Neoplasms 23266581 "Quantitative real-time PCR was applied to measure the levels of 22 microRNAs upregulated in BCA tissue (miR-15a, miR-18a, miR-21, miR-93, miR-96, miR-103, miR-130b, miR-135b, miR-141, miR-182, miR-183, miR-190, miR-191, miR-200b, miR-422b, miR-425, miR-449b, miR-601, miR-639, miR-644, miR-649 and miR-1233) in the marker identification cohort" tissue_expression_up hsa-mir-21 Pancreatic Neoplasms 23272057 "Here, we show, for the first time, that hypoxia leads to increased expression of VEGF, IL-6, and CSC signature genes Nanog, Oct4 and EZH2 consistent with increased cell migration/invasion and angiogenesis, and the formation of pancreatospheres,concomitant with increased expression of miR-21 and miR-210 in human pancreatic cancer (PC) cells" tissue_expression_up hsa-mir-210 Pancreatic Neoplasms 23272057 "Here, we show, for the first time, that hypoxia leads to increased expression of VEGF, IL-6, and CSC signature genes Nanog, Oct4 and EZH2 consistent with increased cell migration/invasion and angiogenesis, and the formation of pancreatospheres,concomitant with increased expression of miR-21 and miR-210 in human pancreatic cancer (PC) cells" tissue_expression_up hsa-mir-372 "Carcinoma, Hepatocellular" 23291979 Upregulation of microRNA-372 associates with tumor progression and prognosis in hepatocellular carcinoma tissue_expression_up hsa-mir-199a-1 Colorectal Carcinoma 23292866 miR-199a-3p may serve as an efficient biomarker for diagnosis and novel prognostic indicator in colorectal cancer tissue_expression_up hsa-mir-199a-2 Colorectal Carcinoma 23292866 miR-199a-3p may serve as an efficient biomarker for diagnosis and novel prognostic indicator in colorectal cancer tissue_expression_up hsa-mir-143 Esophagitis 23297865 "Elevated miR-143, miR-145 and miR-205 expression was observed in oesophageal squamous mucosa of individuals with ulcerative oesophagitis." tissue_expression_up hsa-mir-145 Esophagitis 23297865 "Elevated miR-143, miR-145 and miR-205 expression was observed in oesophageal squamous mucosa of individuals with ulcerative oesophagitis." tissue_expression_up hsa-mir-205 Esophagitis 23297865 "Elevated miR-143, miR-145 and miR-205 expression was observed in oesophageal squamous mucosa of individuals with ulcerative oesophagitis." tissue_expression_up hsa-mir-372 Glioma 23298385 Correlation of microRNA-372 upregulation with poor prognosis in human glioma. tissue_expression_up hsa-mir-155 Waldenstrom Macroglobulinemia 23301642 The most important changes of microRNA are increased expression of miR-155 and decreased expression of miR-9*. tissue_expression_up hsa-mir-124 Heart Failure 23307820 "The significant upregulation of miR-124 and miR-134 in the seizure-related stages and children suggested that both can be potential targets for anticonvulsant drugs in the epileptic developing brains, while the different expression patterns of miR-132 and miR-21 may suggest different functions in MTLE pathogenesis." tissue_expression_up hsa-mir-134 Heart Failure 23307820 "The significant upregulation of miR-124 and miR-134 in the seizure-related stages and children suggested that both can be potential targets for anticonvulsant drugs in the epileptic developing brains, while the different expression patterns of miR-132 and miR-21 may suggest different functions in MTLE pathogenesis." tissue_expression_up hsa-mir-124a "Aortic Aneurysm, Abdominal" 23316282 "MicroRNAs related to fibrosis (miR-29b),inflammation (miR-124a, miR-146a, miR-155, and miR-223), and endothelium(miR-126, let-7 family members, and miR-21) were significantly upregulated in AAA tissue. " tissue_expression_up hsa-mir-126 "Aortic Aneurysm, Abdominal" 23316282 "MicroRNAs related to fibrosis (miR-29b),inflammation (miR-124a, miR-146a, miR-155, and miR-223), and endothelium(miR-126, let-7 family members, and miR-21) were significantly upregulated in AAA tissue. " tissue_expression_up hsa-mir-146a "Aortic Aneurysm, Abdominal" 23316282 "MicroRNAs related to fibrosis (miR-29b),inflammation (miR-124a, miR-146a, miR-155, and miR-223), and endothelium(miR-126, let-7 family members, and miR-21) were significantly upregulated in AAA tissue. " tissue_expression_up hsa-mir-155 "Aortic Aneurysm, Abdominal" 23316282 "MicroRNAs related to fibrosis (miR-29b),inflammation (miR-124a, miR-146a, miR-155, and miR-223), and endothelium(miR-126, let-7 family members, and miR-21) were significantly upregulated in AAA tissue. " tissue_expression_up hsa-mir-223 "Aortic Aneurysm, Abdominal" 23316282 "MicroRNAs related to fibrosis (miR-29b),inflammation (miR-124a, miR-146a, miR-155, and miR-223), and endothelium(miR-126, let-7 family members, and miR-21) were significantly upregulated in AAA tissue. " tissue_expression_up hsa-mir-29b "Aortic Aneurysm, Abdominal" 23316282 "MicroRNAs related to fibrosis (miR-29b),inflammation (miR-124a, miR-146a, miR-155, and miR-223), and endothelium(miR-126, let-7 family members, and miR-21) were significantly upregulated in AAA tissue. " tissue_expression_up hsa-mir-199a-1 "Carcinoma, Hepatocellular" 23319430 Propofol induces apoptosis of hepatocellular carcinoma cells by upregulation of microRNA-199a expression tissue_expression_up hsa-mir-199a-2 "Carcinoma, Hepatocellular" 23319430 Propofol induces apoptosis of hepatocellular carcinoma cells by upregulation of microRNA-199a expression tissue_expression_up hsa-mir-221 "Carcinoma, Hepatocellular" 23320393 Increased MiR-221 expression in hepatocellular carcinoma tissues and its role in enhancing cell growth and inhibiting apoptosis in vitro tissue_expression_up hsa-mir-192 "Diabetes Mellitus, Type 2" 23372846 "Several highly-expressed islet miRNAs, such as miR-375, have established roles in the regulation of islet function, but others (e.g. miR-27b-3p, miR-192-5p) have not previously been described in the context of islet biology." tissue_expression_up hsa-mir-27b "Diabetes Mellitus, Type 2" 23372846 "Several highly-expressed islet miRNAs, such as miR-375, have established roles in the regulation of islet function, but others (e.g. miR-27b-3p, miR-192-5p) have not previously been described in the context of islet biology." tissue_expression_up hsa-mir-375 "Diabetes Mellitus, Type 2" 23372846 "Several highly-expressed islet miRNAs, such as miR-375, have established roles in the regulation of islet function, but others (e.g. miR-27b-3p, miR-192-5p) have not previously been described in the context of islet biology." tissue_expression_up hsa-mir-29c Schizophrenia 23382797 "RT-PCR validation confirmed that two miRNAs, miR-497 in SZ samples and miR-29c in BD samples, have significantly increased expression when compared to control samples. These results warrant future studies to evaluate the potential of exosome-derived miRNAs to serve as biomarkers of SZ and BD." tissue_expression_up hsa-mir-497 Schizophrenia 23382797 "RT-PCR validation confirmed that two miRNAs, miR-497 in SZ samples and miR-29c in BD samples, have significantly increased expression when compared to control samples. These results warrant future studies to evaluate the potential of exosome-derived miRNAs to serve as biomarkers of SZ and BD." tissue_expression_up hsa-mir-21 Thyroid Neoplasms 23416953 "there were significant associations (P<0.05) between BRAF(V600E) and a higher tumor-node-metastasis staging (III/IV), and between miR-21* over-expression and lymph node metastasis." tissue_expression_up hsa-mir-146b "Carcinoma, Thyroid, Papillary" 23427895 "Fourteen miRNAs were deregulated in FVPTC with a fold change of more than five (up/down), including miRNAs known to be upregulated in PTC (miR-146b-3p, -146-5p, -221, -222 and miR-222-5p) and novel miRNAs (miR-375, -551b, 181-2-3p, 99b-3p)." tissue_expression_up hsa-mir-221 "Carcinoma, Thyroid, Papillary" 23427895 "Fourteen miRNAs were deregulated in FVPTC with a fold change of more than five (up/down), including miRNAs known to be upregulated in PTC (miR-146b-3p, -146-5p, -221, -222 and miR-222-5p) and novel miRNAs (miR-375, -551b, 181-2-3p, 99b-3p)." tissue_expression_up hsa-mir-222 "Carcinoma, Thyroid, Papillary" 23427895 "Fourteen miRNAs were deregulated in FVPTC with a fold change of more than five (up/down), including miRNAs known to be upregulated in PTC (miR-146b-3p, -146-5p, -221, -222 and miR-222-5p) and novel miRNAs (miR-375, -551b, 181-2-3p, 99b-3p)." tissue_expression_up hsa-mir-210 Osteosarcoma 23430441 miR-210 upregulation showed a strong correlation with tumor aggressive progression of pediatric osteosarcoma and could help prognostic screening of patients with this malignancy tissue_expression_up hsa-mir-146a Melanoma 23441115 "MiR-146a and miR-26a were overexpressed more than threefold in VH from patients with uveal melanomas compared to the other pathological groups (Wilcoxon signed-rank test, p value <0.05)." tissue_expression_up hsa-mir-26a Melanoma 23441115 "MiR-146a and miR-26a were overexpressed more than threefold in VH from patients with uveal melanomas compared to the other pathological groups (Wilcoxon signed-rank test, p value <0.05)." tissue_expression_up hsa-mir-182 Colorectal Carcinoma 23474644 Up-regulation of miR-182 expression in colorectal cancer tissues and its prognostic value tissue_expression_up hsa-mir-200c Head And Neck Neoplasms 23474763 "expression of p21, miR-34a and miR-200c are increased, demonstrating functional p53 reactivation." tissue_expression_up hsa-mir-34a Head And Neck Neoplasms 23474763 "expression of p21, miR-34a and miR-200c are increased, demonstrating functional p53 reactivation." tissue_expression_up hsa-mir-145 Esophageal Neoplasms 23477513 patients with either decreased miR-135b or increased miR-145 expression in cancer tissue had improved disease-free survival tissue_expression_up hsa-mir-17 Glioblastoma 23497354 In glioblastoma a high ratio of miR-17 to miR-221/222 was predictive of better overall survival suggesting that high miR-221/222 expression is more adverse for patients than high miR-17 expression. tissue_expression_up hsa-mir-221 Glioblastoma 23497354 In glioblastoma a high ratio of miR-17 to miR-221/222 was predictive of better overall survival suggesting that high miR-221/222 expression is more adverse for patients than high miR-17 expression. tissue_expression_up hsa-mir-625 Colorectal Carcinoma 23506979 High expression of microRNA-625-3p is associated with poor response to first-line oxaliplatin based treatment of metastatic colorectal cancer tissue_expression_up hsa-mir-17 Stroke 23511639 These data indicate that the miR17-92 cluster plays an important role in mediating neural progenitor cell function and that the Shh signaling pathway is involved in up-regulating miR17-92 cluster expression. tissue_expression_up hsa-mir-18 Stroke 23511639 These data indicate that the miR17-92 cluster plays an important role in mediating neural progenitor cell function and that the Shh signaling pathway is involved in up-regulating miR17-92 cluster expression. tissue_expression_up hsa-mir-19a Stroke 23511639 These data indicate that the miR17-92 cluster plays an important role in mediating neural progenitor cell function and that the Shh signaling pathway is involved in up-regulating miR17-92 cluster expression. tissue_expression_up hsa-mir-19b-1 Stroke 23511639 These data indicate that the miR17-92 cluster plays an important role in mediating neural progenitor cell function and that the Shh signaling pathway is involved in up-regulating miR17-92 cluster expression. tissue_expression_up hsa-mir-20a Stroke 23511639 These data indicate that the miR17-92 cluster plays an important role in mediating neural progenitor cell function and that the Shh signaling pathway is involved in up-regulating miR17-92 cluster expression. tissue_expression_up hsa-mir-92-1 Stroke 23511639 These data indicate that the miR17-92 cluster plays an important role in mediating neural progenitor cell function and that the Shh signaling pathway is involved in up-regulating miR17-92 cluster expression. tissue_expression_up hsa-mir-125b Leukemia 23550646 "miRNAs such as miR-21, miR-125b, miR-155, miR-196, and miR-210 that are critical for the immune response or hypoxia are often overexpressed in cancers and leukemias" tissue_expression_up hsa-mir-155 Leukemia 23550646 "miRNAs such as miR-21, miR-125b, miR-155, miR-196, and miR-210 that are critical for the immune response or hypoxia are often overexpressed in cancers and leukemias" tissue_expression_up hsa-mir-196 Leukemia 23550646 "miRNAs such as miR-21, miR-125b, miR-155, miR-196, and miR-210 that are critical for the immune response or hypoxia are often overexpressed in cancers and leukemias" tissue_expression_up hsa-mir-21 Leukemia 23550646 "miRNAs such as miR-21, miR-125b, miR-155, miR-196, and miR-210 that are critical for the immune response or hypoxia are often overexpressed in cancers and leukemias" tissue_expression_up hsa-mir-210 Leukemia 23550646 "miRNAs such as miR-21, miR-125b, miR-155, miR-196, and miR-210 that are critical for the immune response or hypoxia are often overexpressed in cancers and leukemias" tissue_expression_up hsa-mir-146a Ovarian Neoplasms 23554878 "These observations suggest that at least two of the miRNAs, miR-146a and miR-150, up-regulated in omental lesions, stimulate survival and increase drug tolerance." tissue_expression_up hsa-mir-150 Ovarian Neoplasms 23554878 "These observations suggest that at least two of the miRNAs, miR-146a and miR-150, up-regulated in omental lesions, stimulate survival and increase drug tolerance." tissue_expression_up hsa-mir-141 Azoospermia 23559187 "Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p" tissue_expression_up hsa-mir-429 Azoospermia 23559187 "Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p" tissue_expression_up hsa-mir-7-1 Azoospermia 23559187 "Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p" tissue_expression_up hsa-mir-7-2 Azoospermia 23559187 "Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p" tissue_expression_up hsa-mir-7-3 Azoospermia 23559187 "Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p" tissue_expression_up hsa-mir-10b Thyroid Neoplasms 23563786 "The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma" tissue_expression_up hsa-mir-221 Thyroid Neoplasms 23563786 "The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma" tissue_expression_up hsa-mir-222 Thyroid Neoplasms 23563786 "The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma" tissue_expression_up hsa-mir-92a-1 Thyroid Neoplasms 23563786 "The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma" tissue_expression_up hsa-mir-92a-2 Thyroid Neoplasms 23563786 "The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma" tissue_expression_up hsa-mir-155 Breast Neoplasms 23568502 17¦Â-Estradiol up-regulates miR-155 expression and reduces TP53INP1 expression in MCF-7 breast cancer cells tissue_expression_up hsa-mir-146b "Carcinoma, Thyroid, Papillary" 23569392 "In addition, the miR-146b expression level was significantly higher in the massive extrathyroidal invasion group than in the minimal extrathyroidal invasion group" tissue_expression_up hsa-mir-145 Glioblastoma 23577178 "Most importantly, higher hsa-miR-145 expression in GBM tumors yielded significantly better survival (p<0.005) in a subset of patients thus validating it as a genuine tumor suppressor miRNA." tissue_expression_up hsa-mir-146a Sepsis 23596477 We observed a significant increase in miR-146a expression in the initial cohort of 6 non-sepsis-SIRS patients compared to the 4 sepsis patients(P=0.01) tissue_expression_up hsa-mir-132 Inflammatory Bowel Diseases 23598815 MiR-132 levels are higher in inflamed compared with apparently quiescent intestinal biopsies from patients with IBD. tissue_expression_up hsa-let-7i Ankylosing Spondylitis 23607629 "In the functional studies, the increased let-7i expression facilitated the T helper type 1 (IFN-¦Ã) immune response in T cells." tissue_expression_up hsa-mir-203 Psoriasis 23608026 "MiR-203 is a miRNA preferentially expressed in the skin, and an important regulator of keratinocyte differentiation. MiR-203 has been implicated in skin diseases, in particular in psoriasis in which it is overexpressed, and in basal cell carcinoma where it acts as a tumor suppressor miRNA." tissue_expression_up hsa-mir-143 "Leukemia, Lymphocytic, Chronic, B-Cell" 23615967 "Significant upregulation of miR-150, miR-29c, miR-143 and miR-223 and downregulation of miR-15a was found in mutated versus unmutated CLL, with miR-15a showing the highest fold difference." tissue_expression_up hsa-mir-150 "Leukemia, Lymphocytic, Chronic, B-Cell" 23615967 "Significant upregulation of miR-150, miR-29c, miR-143 and miR-223 and downregulation of miR-15a was found in mutated versus unmutated CLL, with miR-15a showing the highest fold difference." tissue_expression_up hsa-mir-223 "Leukemia, Lymphocytic, Chronic, B-Cell" 23615967 "Significant upregulation of miR-150, miR-29c, miR-143 and miR-223 and downregulation of miR-15a was found in mutated versus unmutated CLL, with miR-15a showing the highest fold difference." tissue_expression_up hsa-mir-29c "Leukemia, Lymphocytic, Chronic, B-Cell" 23615967 "Significant upregulation of miR-150, miR-29c, miR-143 and miR-223 and downregulation of miR-15a was found in mutated versus unmutated CLL, with miR-15a showing the highest fold difference." tissue_expression_up hsa-mir-181a Breast Neoplasms 23656790 "We report that miR-181a and miR-181b were overexpressed in more aggressive breast cancers, and their expression correlates inversely with ATM levels." tissue_expression_up hsa-mir-181b Breast Neoplasms 23656790 "We report that miR-181a and miR-181b were overexpressed in more aggressive breast cancers, and their expression correlates inversely with ATM levels." tissue_expression_up hsa-mir-210 Heart Failure 23660476 miR-210 and miR-30a were elevated in the HF and fetus groups. tissue_expression_up hsa-mir-30a Heart Failure 23660476 miR-210 and miR-30a were elevated in the HF and fetus groups. tissue_expression_up hsa-mir-10b Ovarian Neoplasms 23670532 Loss of HOXD10 expression induced by upregulation of miR-10b accelerates the migration and invasion activities of ovarian cancer cells. tissue_expression_up hsa-mir-155 Allergic Rhinitis 23704072 "Subjects with current allergic rhinitis symptoms had increased levels of miR-155, miR-205, and miR-498, but reduced levels of let-7e." tissue_expression_up hsa-mir-205 Allergic Rhinitis 23704072 "Subjects with current allergic rhinitis symptoms had increased levels of miR-155, miR-205, and miR-498, but reduced levels of let-7e." tissue_expression_up hsa-mir-498 Allergic Rhinitis 23704072 "Subjects with current allergic rhinitis symptoms had increased levels of miR-155, miR-205, and miR-498, but reduced levels of let-7e." tissue_expression_up hsa-mir-328 Atrial Fibrillation 23710743 miR-328 expression is significantly increased in patients with AF tissue_expression_up hsa-mir-130a Pulmonary Hypertension 23717609 "We identified several novel downregulated miRNAs (miR-451, miR-1246) and upregulated miRNAs (miR-23b, miR-130a and miR-191) in the circulation of PH subjects." tissue_expression_up hsa-mir-191 Pulmonary Hypertension 23717609 "We identified several novel downregulated miRNAs (miR-451, miR-1246) and upregulated miRNAs (miR-23b, miR-130a and miR-191) in the circulation of PH subjects." tissue_expression_up hsa-mir-23b Pulmonary Hypertension 23717609 "We identified several novel downregulated miRNAs (miR-451, miR-1246) and upregulated miRNAs (miR-23b, miR-130a and miR-191) in the circulation of PH subjects." tissue_expression_up hsa-mir-192 "Adenocarcinoma, Esophageal" 23724052 "6 miRNAs (up-regulated: miR-194, miR-31, miR-192, and miR-200a; down-regulated: miR-203 and miR-205) in EAC" tissue_expression_up hsa-mir-194 "Adenocarcinoma, Esophageal" 23724052 "6 miRNAs (up-regulated: miR-194, miR-31, miR-192, and miR-200a; down-regulated: miR-203 and miR-205) in EAC" tissue_expression_up hsa-mir-200a "Adenocarcinoma, Esophageal" 23724052 "6 miRNAs (up-regulated: miR-194, miR-31, miR-192, and miR-200a; down-regulated: miR-203 and miR-205) in EAC" tissue_expression_up hsa-mir-203 "Adenocarcinoma, Esophageal" 23724052 "6 miRNAs (up-regulated: miR-194, miR-31, miR-192, and miR-200a; down-regulated: miR-203 and miR-205) in EAC" tissue_expression_up hsa-mir-205 "Adenocarcinoma, Esophageal" 23724052 "6 miRNAs (up-regulated: miR-194, miR-31, miR-192, and miR-200a; down-regulated: miR-203 and miR-205) in EAC" tissue_expression_up hsa-mir-31 "Adenocarcinoma, Esophageal" 23724052 "6 miRNAs (up-regulated: miR-194, miR-31, miR-192, and miR-200a; down-regulated: miR-203 and miR-205) in EAC" tissue_expression_up hsa-mir-130b Inflammation 23733276 "Statistical analysis considering liver donor meta-data including correction for multiple testing revealed strongly elevated levels of miR-21, miR-34a, miR-130b, and miR-132 in cholestatic liver and of miR-21 and miR-130b during inflammation, as indicated by elevated C-reactive protein levels in serum." tissue_expression_up hsa-mir-132 Inflammation 23733276 "Statistical analysis considering liver donor meta-data including correction for multiple testing revealed strongly elevated levels of miR-21, miR-34a, miR-130b, and miR-132 in cholestatic liver and of miR-21 and miR-130b during inflammation, as indicated by elevated C-reactive protein levels in serum." tissue_expression_up hsa-mir-21 Inflammation 23733276 "Statistical analysis considering liver donor meta-data including correction for multiple testing revealed strongly elevated levels of miR-21, miR-34a, miR-130b, and miR-132 in cholestatic liver and of miR-21 and miR-130b during inflammation, as indicated by elevated C-reactive protein levels in serum." tissue_expression_up hsa-mir-34a Inflammation 23733276 "Statistical analysis considering liver donor meta-data including correction for multiple testing revealed strongly elevated levels of miR-21, miR-34a, miR-130b, and miR-132 in cholestatic liver and of miR-21 and miR-130b during inflammation, as indicated by elevated C-reactive protein levels in serum." tissue_expression_up hsa-mir-221 Obesity 23756832 Human adipose microRNA-221 is upregulated in obesity and affects fat metabolism downstream of leptin and TNF-alpha tissue_expression_up hsa-mir-101-1 Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-101-2 Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-130a Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-130b Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-143 Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-15a Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-196b Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-200a Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-210 Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-27a Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-28 Esophageal Neoplasms 23761828 miR-28-3p: upregulated tissue_expression_up hsa-mir-31 Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-452 Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-99b Esophageal Neoplasms 23761828 upregulated tissue_expression_up hsa-mir-192 Ovarian Neoplasms 23766361 "The clear cell histotype is characterized by a five-fold (log scale) higher expression of miR-30a and miR-30a*, while mucinous histotype has five-fold (log scale) higher levels of miR-192/194. Furthermore a mucinous-specific regulatory loop involving miR-192/194 cluster and a differential regulation of E2F3 in clear cell histotype were identified." tissue_expression_up hsa-mir-194-1 Ovarian Neoplasms 23766361 "The clear cell histotype is characterized by a five-fold (log scale) higher expression of miR-30a and miR-30a*, while mucinous histotype has five-fold (log scale) higher levels of miR-192/194. Furthermore a mucinous-specific regulatory loop involving miR-192/194 cluster and a differential regulation of E2F3 in clear cell histotype were identified." tissue_expression_up hsa-mir-194-2 Ovarian Neoplasms 23766361 "The clear cell histotype is characterized by a five-fold (log scale) higher expression of miR-30a and miR-30a*, while mucinous histotype has five-fold (log scale) higher levels of miR-192/194. Furthermore a mucinous-specific regulatory loop involving miR-192/194 cluster and a differential regulation of E2F3 in clear cell histotype were identified." tissue_expression_up hsa-mir-30a Ovarian Neoplasms 23766361 "The clear cell histotype is characterized by a five-fold (log scale) higher expression of miR-30a and miR-30a*, while mucinous histotype has five-fold (log scale) higher levels of miR-192/194. Furthermore a mucinous-specific regulatory loop involving miR-192/194 cluster and a differential regulation of E2F3 in clear cell histotype were identified." tissue_expression_up hsa-mir-34a Breast Neoplasms 23771315 Synergistic effects of curcumin with emodin against the proliferation and invasion of breast cancer cells through upregulation of mir-34a. tissue_expression_up hsa-mir-874 Gastric Neoplasms 23800944 "These results provide a mechanism by which AQP3 is upregulated, as well as highlight the importance of miR-874 in gastric cancer development and progression." tissue_expression_up hsa-mir-181c Gastric Neoplasms 23803080 "The expression of miR-181c is upregulated in GC tissues and plasma, and the miR-181c expression level in GC plasma is positively correlated to that in the corresponding cancer tissues. Plasma miR-181c is possibly a new serological marker for GC diagnosis." tissue_expression_up hsa-mir-107 Glioma 23811124 Low-expression of microRNA-107 inhibits cell apoptosis in glioma by upregulation of SALL4. tissue_expression_up hsa-mir-19a Glioma 23824915 miR-19a and miR-19b overexpression in gliomas. tissue_expression_up hsa-mir-19b Glioma 23824915 miR-19a and miR-19b overexpression in gliomas. tissue_expression_up hsa-mir-146b Intestinal Schistosomiasis 23825609 "miRNAs exhibiting a peak expression in the late phase of infection (dpi 45), such as mmu-miR-223, mmu-miR-146a/b, mmu-miR-155, mmu-miR-34c, mmu-miR-199, and mmu-miR-134, may represent a molecular ignature of the development of schistosomal hepatopathy." tissue_expression_up hsa-mir-124 Stroke 23826665 The level of miR-124 is significantly increased in ischemic penumbra as compared with that in nonischemic area of MACO mice. tissue_expression_up hsa-mir-301a Gastric Neoplasms 23832550 "miR-301a overexpression correlated with TNM stage and prognosis,suggesting that miR-301a is involved in cellular clone formation, migration, and invasion in vitro and may play an important role in the clinical progression and prognosis of gastric cancer." tissue_expression_up hsa-mir-200b Gastric Neoplasms 23851184 Diallyl disulfide suppresses proliferation and induces apoptosis in human gastric cancer through Wnt-1 signaling pathway by up-regulation of miR-200b and miR-22. tissue_expression_up hsa-mir-22 Gastric Neoplasms 23851184 Diallyl disulfide suppresses proliferation and induces apoptosis in human gastric cancer through Wnt-1 signaling pathway by up-regulation of miR-200b and miR-22. tissue_expression_up hsa-mir-155 "Carcinoma, Hepatocellular" 23863669 MicroRNA-155 is over-expressed in primary HCC with tumor recurrence and may serve as a novel biomarker for tumor recurrence and survival of HCC patients after LT. The detection of microRNA-155 is of clinical significance in HCC. tissue_expression_up hsa-mir-675 "Carcinoma, Hepatocellular" 23864307 Expression of the miR-675 in hepatocellular carcinoma links a dramatic upregulation of proliferative and growth capacity with inhibition of motility in HCC cells. tissue_expression_up hsa-mir-21 Gastric Neoplasms 23888942 Oxidative stress upregulates PDCD4 expression in patients with gastric cancer via miR-21. tissue_expression_up hsa-mir-27 Hepatitis C Virus Infection 23897856 Hepatitis C virus induced up-regulation of microRNA-27: a novel mechanism for hepatic steatosis. tissue_expression_up hsa-mir-143 Lung Neoplasms 23904792 "The up-regulated miR-143 in lung cancer could significantly inhibit cell migration and invasion, and this might work through targeting CD44v3, which was newly identified by us." tissue_expression_up hsa-mir-203 Ovarian Neoplasms 23918241 Upregulation of microRNA-203 is associated with advanced tumor progression and poor prognosis in epithelial ovarian cancer. tissue_expression_up hsa-mir-182 Prostate Neoplasms 23936432 Inhibition of proliferation and induction of autophagy by atorvastatin in PC3 prostate cancer cells correlate with downregulation of Bcl2 and upregulation of miR-182 and p21. tissue_expression_up hsa-mir-31 Choriocarcinoma 23946296 MicroRNA-31 predicts the presence of lymph node metastases and survival in patients with lung adenocarcinoma. tissue_expression_up hsa-mir-138 "Carcinoma, Bladder" 23946872 "Within this group, let-7b and let-7i exhibited decreased expression, while miR-1290 and miR-138 displayed increased expression levels in gemcitabine-resistant cells." tissue_expression_up hsa-mir-132 Inflammation 23951048 Chronic ethanol feeding up-regulated miR-155 and miR-132 expression in mouse cerebellum. tissue_expression_up hsa-mir-10a Breast Neoplasms 23968733 Increased expression of miR-126 and miR-10a predict prolonged relapse-free time of primary oestrogen receptor-positive breast cancer following tamoxifen treatment. tissue_expression_up hsa-mir-126 Breast Neoplasms 23968733 Increased expression of miR-126 and miR-10a predict prolonged relapse-free time of primary oestrogen receptor-positive breast cancer following tamoxifen treatment. tissue_expression_up hsa-mir-18b Breast Neoplasms 23970382 MicroRNA-18b is upregulated in breast cancer and modulates genes involved in cell migration. tissue_expression_up hsa-mir-215 Gastric Neoplasms 23981575 Frequently up-regulated miR-215 in gastric cancer may influence cell proliferation by targeting RB1. tissue_expression_up hsa-mir-9 Lung Neoplasms 24019037 "MiR-9 was up-regulated in non-small cell lung cancer tissues and correlated with adverse clinical features and unfavorable survival, indicating that miR-9 might be involved in non-small lung cancer progression and could serve as a promising biomarker for further risk stratification in the treatment of this cancer." tissue_expression_up hsa-mir-26b Alzheimer Disease 24027266 "MiR-26b, upregulated in Alzheimer's disease, activates cell cycle entry,tau-phosphorylation, and apoptosis in postmitotic neurons." tissue_expression_up hsa-mir-126 "Carcinoma, Cervical" 24037526 Repression of miR-126 and upregulation of adrenomedullin in the stromal endothelium by cancer-stromal cross talks confers angiogenesis of cervical cancer. tissue_expression_up hsa-mir-214 Pediatric Osteosarcoma 24038809 Our data offer evidence that upregulated expression of miR-214 may be linked to tumor progression and adverse prognosis in pediatric osteosarcoma.Further investigation in prospective studies would appear warranted. tissue_expression_up hsa-mir-1 Myocardial Infarction 24046434 "Consistent with previous publications, cardiac specific miR-1 and miR-133a were up-regulated in STEMI patients compared with healthy controls (both, P < 0.0001)" tissue_expression_up hsa-mir-182 "Carcinoma, Colon" 24053448 "Our data suggest that miR-182 targets the anti-angiogenic factor TSP-1 and that anti-miR-182 determines an upregulation of TSP-1 expression in colon cancer cells. Moreover, anti-miR-182 exerts a transcriptional regulatory mechanism of tsp-1 modulating Egr-1 and Sp-1 function. Anti-miR-182 could be used to restore TSP-1 expression in order to contrast angiogenic and invasive events in CRC." tissue_expression_up hsa-mir-9 Glioma 24122417 Increased expression of microRNA-9 predicts an unfavorable prognosis in human glioma. tissue_expression_up hsa-mir-21 "Carcinoma, Colon" 24122631 High miR-21 expression from FFPE tissues is associated with poor survival and response to adjuvant chemotherapy in colon cancer. tissue_expression_up hsa-mir-222 "Carcinoma, Hepatocellular" 24124720 "Serum miR-222, upregulated in HCC, maybe helpful in prognosis of HCC patients." tissue_expression_up hsa-mir-222 Ovarian Neoplasms 24137356 miR-222 is upregulated in epithelial ovarian cancer and promotes cell proliferation by downregulating P27kip1. tissue_expression_up hsa-mir-32 "Muscular Dystrophy, Facioscapulohumeral" 24145033 "Twenty-one microRNAs (miR-1, miR-7, miR-15a, miR-22, miR-30e, miR-32, miR-107, miR-133a, miR-133b, miR-139, miR-152, miR-206, miR-223, miR-302b, miR-331, miR-362, miR-365, miR-382, miR-496, miR-532, miR-654, and miR-660) were up-regulated" tissue_expression_up hsa-mir-525 Neoplasms [unspecific] 24147004 "The transient up-regulation of miR-525-3p, and the resultant repression of its direct targets ARRB1, TXN1 and HSPA9, is required for cell survival following irradiation. The conserved function of miR-525-3p across several cell types makes this microRNA pathway a promising target for modifying the efficacy of radiotherapy." tissue_expression_up hsa-mir-183 Colorectal Carcinoma 24150523 "The increased expression of miR-183 is closely related to advanced clinical stage, lymph node and distant metastases, and poor prognosis of CRC,indicating that miR-183 may serve as a predictive biomarker for the prognosis or the aggressiveness of CRC." tissue_expression_up hsa-mir-155 Rheumatoid Arthritis 24151514 "An inflammatory milieu may alter miRNA expression profiles in rheumatoid arthritis. miR-155 is upregulated in RA-FLS, and it may be a protective factor against the inflammatory effect in part by attenuating expression of IKBKE." tissue_expression_up hsa-mir-221 Glioblastoma 24155920 "A number of changes in the levels of microRNAs were detected in differentiating GICs, including over-expression of hsa-miR-21, hsa-miR-29a, hsa-miR-29b, hsa-miR-221 and hsa-miR-222, and down-regulation of hsa-miR-93 and hsa-miR-106a." tissue_expression_up hsa-mir-222 Glioblastoma 24155920 "A number of changes in the levels of microRNAs were detected in differentiating GICs, including over-expression of hsa-miR-21, hsa-miR-29a, hsa-miR-29b, hsa-miR-221 and hsa-miR-222, and down-regulation of hsa-miR-93 and hsa-miR-106a." tissue_expression_up hsa-mir-125b Glioblastoma 24169356 High-level expression of miR-125b is associated with poor outcomes of GMB. MiR-125b may have an oncogenic role in GMB cells by promoting cell proliferation and inhibiting apoptosis. tissue_expression_up hsa-mir-518b Chondrosarcoma 24173143 Gallic acid induces apoptosis and inhibits cell migration by upregulating miR-518b in SW1353 human chondrosarcoma cells. tissue_expression_up hsa-mir-122 "Carcinoma, Renal Cell" 24175769 The up-regulation of miR-122 may play an important role in the progress of renal cancer through activating PI3K/Akt signal pathway and could be a potential molecular target for anti-cancer therapeutics. tissue_expression_up hsa-mir-198 "Carcinoma, Esophageal" 24175778 miR-198 overexpression is involved in the poor prognosis of esophageal cancer and can be used as a biomarker for selection of cases requiring especial attention. tissue_expression_up hsa-mir-29a Neoplasms [unspecific] 24210072 MicroRNA-29a upregulates MMP2 in oral squamous cell carcinoma to promote cancer invasion and anti-apoptosis. tissue_expression_up hsa-mir-31 "Squamous Cell Carcinoma, Oral" 24238414 The up-regulated level of microRNA-31 expression may be related to the pathogenesis of OSCC. tissue_expression_up hsa-mir-150 Chronic Heart Failure 24239242 MicroRNA-150 counteracts ADIPOR2 up-regulation in CHF and thus may contribute to adiponectin resistance. Targeting microRNA-150 may be a future strategy to restore cardioprotective adiponectin effects. tissue_expression_up hsa-mir-424 Prostate Neoplasms 24244675 MiR-424/503-mediated Rictor upregulation promotes tumor progression. tissue_expression_up hsa-mir-503 Prostate Neoplasms 24244675 MiR-424/503-mediated Rictor upregulation promotes tumor progression. tissue_expression_up hsa-mir-21 Colorectal Carcinoma 24265822 The present findings suggest that high expression of miR-21 might predict poor prognosis in patients with colorectal cancer. tissue_expression_up hsa-mir-25 Colorectal Carcinoma 24293092 The expression of miR-25 is increased in colorectal cancer and is associated with patient prognosis. tissue_expression_up hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 24293118 Our data suggest a novel molecular mechanism in which inhibition of microRNA-21 and upregulation of PTEN mediate the anticancer activities of curcumin in NSCLC cells. Suppression of microRNA-21 may thus have therapeutic benefits against this malignancy. tissue_expression_up hsa-mir-655 "Squamous Cell Carcinoma, Esophageal" 24314023 Mir-655 up-regulation suppresses cell invasion by targeting pituitary tumor-transforming gene-1 in esophageal squamous cell carcinoma. tissue_expression_up hsa-mir-143 "Diabetes Mellitus, Type 2" 24333576 Adipocyte-derived factors impair insulin signaling in differentiated human vascular smooth muscle cells via the upregulation of miR-143. tissue_expression_up hsa-mir-125b Amyotrophic Lateral Sclerosis 24336079 "We identified upregulation of selected immune-enriched miRNAs, recognizing miR-22, miR-155, miR-125b and miR-146b among the most highly modulated." tissue_expression_up hsa-mir-146b Amyotrophic Lateral Sclerosis 24336079 "We identified upregulation of selected immune-enriched miRNAs, recognizing miR-22, miR-155, miR-125b and miR-146b among the most highly modulated." tissue_expression_up hsa-mir-23b Lymphoma 24356489 We found that miR-23a & miR-23b were up-regulated in radiation induced thymic lymphoma tissue samples. tissue_expression_up hsa-mir-210 Glioma 24382515 MicroRNA-210 overexpression predicts poorer prognosis in glioma patients. tissue_expression_up hsa-mir-98 Glioma 24392454 Overexpression of RKIP inhibits cell invasion in glioma cell lines through upregulation of miR-98. tissue_expression_up hsa-mir-128 Salmonellosis 24415783 "Salmonella can upregulate intestinal epithelial miR-128 expression,which, in turn, decreases levels of epithelial cell-secreted M-CSF and M-CSF-induced macrophage recruitment. mir-9-5p" tissue_expression_up hsa-mir-155 "Squamous Cell Carcinoma, Oral" 24439918 "In OSSC, upregulation of miR-155 correlated with the histologic grade and can be used as a potential prognostic biomarker." tissue_expression_up hsa-mir-146 "Carcinoma, Lung, Non-Small-Cell" 24448024 microRNA-146 up-regulation predicts the prognosis of non-small cell lung cancer by miRNA in situ hybridization. tissue_expression_up hsa-mir-17 Melanoma 24462553 "We show that miRNAs of the miR-17-92 cluster (miR-20a2, miR-92a1, miR-17 and miR-18a), miR-126, miR-182, miR-210 and miR-214 are upregulated and their respective target genes (RUNX1, HIF1A, TGFBR2, THBS1 and JAK2) are down-regulated in melanoma." tissue_expression_up hsa-mir-214 Melanoma 24462553 "We show that miRNAs of the miR-17-92 cluster (miR-20a2, miR-92a1, miR-17 and miR-18a), miR-126, miR-182, miR-210 and miR-214 are upregulated and their respective target genes (RUNX1, HIF1A, TGFBR2, THBS1 and JAK2) are down-regulated in melanoma." tissue_expression_up hsa-mir-214 Ovarian Neoplasms 24479883 "Members of the miR-200 family, miR-182, miR-214 and miR-221 are frequently up-regulated, whereas miR-100, let-7i, miR-199a, miR-125b, mir-145 and miR-335 are often down-regulated in ovarian cancer compared with normal ovarian tissue." tissue_expression_up hsa-mir-30a Ovarian Neoplasms 24479883 "Clear cell carcinoma has a significantly higher expression of miR-30a and miR-30a*, whereas mucinous histotype has elevated levels of miR-192/194." tissue_expression_up hsa-mir-888 Breast Neoplasms 24480745 "As a potential role in intercellular adhesiveness and maintenance of malignant tissue architecture, the results indicate that miR-888 is a repressor of the AJ pathway in MCF-7 cells and that up-regulation of miR-888 contributes to aggressiveness in MCF-7 SP cells." tissue_expression_up hsa-mir-31 Oral Neoplasms 24480806 miR-31 is upregulated in oral premalignant epithelium and contributes to the immortalization of normal oral keratinocytes. tissue_expression_up hsa-mir-135b "Carcinoma, Endometrioid Endometrial" 24491411 "Quantitative reverse-transcriptase PCR identified 8 EEC-associated miRNAs in tissue (upregulated: miR-499, miR-135b, miR-205, downregulated: miR-10b, miR-195, miR-30a-5p, miR-30a-3p and miR-21)." tissue_expression_up hsa-mir-145 Endometriosis 24495683 "Up-regulation of mir-29c, mir-200a, mir-145 in the endometrial tissue might play a role in endometriosis associated infertility." tissue_expression_up hsa-mir-200a Endometriosis 24495683 "Up-regulation of mir-29c, mir-200a, mir-145 in the endometrial tissue might play a role in endometriosis associated infertility." tissue_expression_up hsa-mir-29c Endometriosis 24495683 "Up-regulation of mir-29c, mir-200a, mir-145 in the endometrial tissue might play a role in endometriosis associated infertility." tissue_expression_up hsa-mir-143 Allergic Rhinitis 24513959 "Downregulation of miR-18a, miR-126, let-7e, miR-155, and miR-224 and upregulation of miR-498, miR-187, miR-874, miR-143, and miR-886-3p were observed in asthmatic patients in comparison to controls. The differences in miRNA expression were mainly similar in asthmatics with and without AR." tissue_expression_up hsa-mir-143 Asthma 24513959 "Downregulation of miR-18a, miR-126, let-7e, miR-155, and miR-224 and upregulation of miR-498, miR-187, miR-874, miR-143, and miR-886-3p were observed in asthmatic patients in comparison to controls. The differences in miRNA expression were mainly similar in asthmatics with and without AR." tissue_expression_up hsa-mir-187 Allergic Rhinitis 24513959 "Downregulation of miR-18a, miR-126, let-7e, miR-155, and miR-224 and upregulation of miR-498, miR-187, miR-874, miR-143, and miR-886-3p were observed in asthmatic patients in comparison to controls. The differences in miRNA expression were mainly similar in asthmatics with and without AR." tissue_expression_up hsa-mir-187 Asthma 24513959 "Downregulation of miR-18a, miR-126, let-7e, miR-155, and miR-224 and upregulation of miR-498, miR-187, miR-874, miR-143, and miR-886-3p were observed in asthmatic patients in comparison to controls. The differences in miRNA expression were mainly similar in asthmatics with and without AR." tissue_expression_up hsa-mir-498 Allergic Rhinitis 24513959 "Downregulation of miR-18a, miR-126, let-7e, miR-155, and miR-224 and upregulation of miR-498, miR-187, miR-874, miR-143, and miR-886-3p were observed in asthmatic patients in comparison to controls. The differences in miRNA expression were mainly similar in asthmatics with and without AR." tissue_expression_up hsa-mir-498 Asthma 24513959 "Downregulation of miR-18a, miR-126, let-7e, miR-155, and miR-224 and upregulation of miR-498, miR-187, miR-874, miR-143, and miR-886-3p were observed in asthmatic patients in comparison to controls. The differences in miRNA expression were mainly similar in asthmatics with and without AR." tissue_expression_up hsa-mir-874 Allergic Rhinitis 24513959 "Downregulation of miR-18a, miR-126, let-7e, miR-155, and miR-224 and upregulation of miR-498, miR-187, miR-874, miR-143, and miR-886-3p were observed in asthmatic patients in comparison to controls. The differences in miRNA expression were mainly similar in asthmatics with and without AR." tissue_expression_up hsa-mir-874 Asthma 24513959 "Downregulation of miR-18a, miR-126, let-7e, miR-155, and miR-224 and upregulation of miR-498, miR-187, miR-874, miR-143, and miR-886-3p were observed in asthmatic patients in comparison to controls. The differences in miRNA expression were mainly similar in asthmatics with and without AR." tissue_expression_up hsa-mir-886 Allergic Rhinitis 24513959 "Downregulation of miR-18a, miR-126, let-7e, miR-155, and miR-224 and upregulation of miR-498, miR-187, miR-874, miR-143, and miR-886-3p were observed in asthmatic patients in comparison to controls. The differences in miRNA expression were mainly similar in asthmatics with and without AR." tissue_expression_up hsa-mir-886 Asthma 24513959 "Downregulation of miR-18a, miR-126, let-7e, miR-155, and miR-224 and upregulation of miR-498, miR-187, miR-874, miR-143, and miR-886-3p were observed in asthmatic patients in comparison to controls. The differences in miRNA expression were mainly similar in asthmatics with and without AR." tissue_expression_up hsa-mir-182 "Carcinoma, Lung, Non-Small-Cell" 24575749 "In patients with SCC and in stage II patients, high tumor cell miR-182 expression is an independent positive prognostic factor." tissue_expression_up hsa-mir-25 "Carcinoma, Hepatocellular" 24593846 Our data suggests that the overexpression of miR-25 in HCC tissues is of predictive value on poor prognosis. tissue_expression_up hsa-mir-206 Alzheimer Disease 24604632 "We now report that miR-206 is upregulated in the hippocampal tissue, cerebrospinal fluid, and plasma of embryonic APP/PS1 transgenic mice." tissue_expression_up hsa-mir-93 Breast Neoplasms 24606013 These results suggest that overexpression of miR-93 in FFPE tissues may serve as an indispensable source for biomarker discovery and validation in breast cancer patients. tissue_expression_up hsa-mir-126 Asthma 24615202 In mice models of asthma it has been found that increased levels of miR-21 and miR-126 tissue_expression_up hsa-mir-630 Gastric Neoplasms 24621930 Increased microRNA-630 expression in gastric cancer is associated with poor overall survival. tissue_expression_up hsa-mir-196a Pancreatic Intraductal Papillary Mucinous Neoplasms 24622064 Elevated expression of miR-196a in pancreatic juice samples is predictive of intestinal-type IPMNs. tissue_expression_up hsa-mir-125b Melanoma 24635082 "MLK3 is upregulated in metastatic melanoma, and regulates cell proliferation and invasion in melanoma cells. MLK3 is a direct target of miR-125b." tissue_expression_up hsa-mir-149 Lung Fibrosis 24641842 Down-regulation of miR-149 and up-regulation of IL-6 might be involved in the progression of silica-induced pulmonary fibrosis; miR-149 could negatively regulate IL-6 expression. tissue_expression_up hsa-mir-17 Osteosarcoma 24645838 Upregulation of microRNA-17-92 cluster associates with tumor progression and prognosis in osteosarcoma. tissue_expression_up hsa-mir-106a Colorectal Carcinoma 24670448 "plasma miR-106a is up-regulated in CRC patients, suggesting its potential value for the diagnosis of CRC." tissue_expression_up hsa-mir-155 "Squamous Cell Carcinoma, Oral" 24692283 "MiRNA-155 was overexpressed in OSCC and it was located in the cancer nest, inflammatory area, and vascular endothelium of OSCC. High miRNA-155 expression level in ACF may predict poor prognosis in patients with OSCC." tissue_expression_up hsa-mir-1224 Acute Kidney Failure 24695114 "Ischemia-reperfusion caused highly reproducible, progressive, concordant elevation of miR-714, miR-1188, miR-1897-3p, miR-877*, and miR-1224 in plasma and kidneys at 3, 6 and 24 hours after acute kidney injury compared to the sham-operated mice (nâ€?â€?)." tissue_expression_up hsa-mir-25 "Carcinoma, Ovarian" 24696291 "The increased expression of miR-25 is closely related to poor prognosis of EOC, indicating that miR-25 may serve as a predictive biomarker for the prognosis of EOC." tissue_expression_up hsa-mir-98 Breast Neoplasms 24696733 Over-expression of miR-98 in FFPE tissues might serve as a valuable source for biomarker discovery in breast cancer patients. tissue_expression_up hsa-mir-218 "Adenocarcinoma, Lung" 24705471 ADAM9 up-regulates N-cadherin via miR-218 suppression in lung adenocarcinoma cells. tissue_expression_up hsa-mir-199a Colorectal Carcinoma 24711074 MiR-199a-5p loss up-regulated DDR1 aggravated colorectal cancer by activating epithelial-to-mesenchymal transition related signaling. tissue_expression_up hsa-let-7b Infertility 24711889 "Mir-100, let-7b levels were significantly higher than those in control group (P=0.008 and P=0.009, respectively)." tissue_expression_up hsa-mir-223 Knee Osteoarthritis 24727161 Peroxisomal dysfunction is associated with up-regulation of apoptotic cell death via miR-223 induction in knee osteoarthritis patients with type 2 diabetes mellitus. tissue_expression_up hsa-mir-4284 Glioblastoma 24732116 "A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via up-regulation of miRNA-4284 and JNK/AP-1 signaling." tissue_expression_up hsa-mir-21 Acute Lung Injury 24736893 miR-21 was upregulated in the OA group throughout the 24 h following OA challenge. tissue_expression_up hsa-mir-1246 Neuroblastoma 24739954 Parallel mRNA and microRNA profiling of HEV71-infected human neuroblastoma cells reveal the up-regulation of miR-1246 in association with DLG3 repression. tissue_expression_up hsa-mir-196a Osteosarcoma 24747591 "Our present data indicate the involvement of miR-196a and miR-196b upregulation in the pathogenesis of osteosarcoma. More importantly, the altered levels of circulating miR-196a and miR-196b might have great potential to serve as novel and non-invasive prognostic factors for this malignancy." tissue_expression_up hsa-mir-196b Osteosarcoma 24747591 "Our present data indicate the involvement of miR-196a and miR-196b upregulation in the pathogenesis of osteosarcoma. More importantly, the altered levels of circulating miR-196a and miR-196b might have great potential to serve as novel and non-invasive prognostic factors for this malignancy." tissue_expression_up hsa-mir-21 "Carcinoma, Esophageal" 24756761 Nicotine upregulates microRNA-21 and promotes TGF-¦Â-dependent epithelial-mesenchymal transition of esophageal cancer cells. tissue_expression_up hsa-mir-378 Obesity 24771406 "TNF-¦Á, IL-6, and leptin upregulated miR-378 expression indicating that miR-378 probably is a novel mediator in the development of insulin resistance related to obesity." tissue_expression_up hsa-mir-21 "Carcinoma, Breast" 24781337 Higher miR-21 expression in invasive breast carcinomas is associated with positive estrogen and progesterone receptor status in patients from Serbia. tissue_expression_up hsa-mir-183 "Adenocarcinoma, Lung" 24805982 Up-regulation of microRNA-183-3p is a potent prognostic marker for lung adenocarcinoma of female non-smokers. tissue_expression_up hsa-mir-26b "Adenocarcinoma, Lung" 24815696 Huaier suppresses proliferation and induces apoptosis in human pulmonary cancer cells via upregulation of miR-26b-5p. tissue_expression_up hsa-mir-196a "Carcinoma, Cervical" 24817935 Heterogeneity of microRNAs expression in cervical cancer cells: over-expression of miR-196a. tissue_expression_up hsa-mir-23b "Leukemia, Myeloid, Acute" 24828865 MicroRNA-26a-5p and microRNA-23b-3p up-regulate peroxiredoxin III in acute myeloid leukemia. tissue_expression_up hsa-mir-26a "Leukemia, Myeloid, Acute" 24828865 MicroRNA-26a-5p and microRNA-23b-3p up-regulate peroxiredoxin III in acute myeloid leukemia. tissue_expression_up hsa-mir-155 "Carcinoma, Lung, Non-Small-Cell" 24854560 High expression of miR-155 represents a valuable marker of poor clinical outcomes in patients with stage III NSCLC. tissue_expression_up hsa-mir-9 Ovarian Neoplasms 24870723 The present study provided evidence that curcumin exerts its cytotoxic effects against SKOV3 ovarian cancer cells largely through upregulation of miR-9 and subsequent modulation of Akt/FOXO1 axis. Further studies are needed to identify direct targets of miR-9 that mediate the anticancer effects of curcumin in ovarian cancer cells. tissue_expression_up hsa-mir-155 "Carcinoma, Colon" 24888652 "The expression of miR-155 is up-regulated in colon cancer tissue. A combination of miR-155 level assay in colon cancer tissue and the serum CEA level both pre- and postoperatively can afford more accurate information for diagnosis and prognosis, especially for predicting recurrence and metastasis postoperatively." tissue_expression_up hsa-mir-155 Rheumatoid Arthritis 24909288 "TPT suppressed the expression of miR-155 and up-regulated the release of SHIP-1, thus inhibiting the inflammatory response in the LPS-stimulated monocytes of RA patients." tissue_expression_up hsa-mir-224 "Carcinoma, Hepatocellular" 24923856 These results indicate for the first time that miR-224 upregulation and AKT activation may synergistically associate with tumor progression of HCC.The combined high expression of miR-224 and pAKT may be a potential indicator for predicting unfavorable prognosis in HCC patients. tissue_expression_up hsa-mir-21 "Carcinoma, Breast, Triple Negative" 24930006 High expression of miR-21 in triple-negative breast cancers was correlated with a poor prognosis and promoted tumor cell in vitro proliferation. tissue_expression_up hsa-mir-326 Multiple Sclerosis 24936144 "For instance, miR-21, miR-142-3p, miR-146a, miR-146b, miR-155 and miR-326 were up-regulated in both peripheral blood mononuclear cells (PBMCs) and brain white matter lesions from MS patients and mouse model as well." tissue_expression_up hsa-mir-155 Early-Stage Breast Carcinoma 24938880 OncomiRs are significantly more abundant in the sera of EBC patients compared to controls at diagnosis. Differences in oncomiR levels reflecting EBC risk were also observed. Testing the oncomiRs may be useful for diagnostic purpose and possibly also for relapse detection in follow-up studies of EBC. tissue_expression_up hsa-mir-181b Early-Stage Breast Carcinoma 24938880 OncomiRs are significantly more abundant in the sera of EBC patients compared to controls at diagnosis. Differences in oncomiR levels reflecting EBC risk were also observed. Testing the oncomiRs may be useful for diagnostic purpose and possibly also for relapse detection in follow-up studies of EBC. tissue_expression_up hsa-mir-19a Early-Stage Breast Carcinoma 24938880 OncomiRs are significantly more abundant in the sera of EBC patients compared to controls at diagnosis. Differences in oncomiR levels reflecting EBC risk were also observed. Testing the oncomiRs may be useful for diagnostic purpose and possibly also for relapse detection in follow-up studies of EBC. tissue_expression_up hsa-mir-24 Early-Stage Breast Carcinoma 24938880 OncomiRs are significantly more abundant in the sera of EBC patients compared to controls at diagnosis. Differences in oncomiR levels reflecting EBC risk were also observed. Testing the oncomiRs may be useful for diagnostic purpose and possibly also for relapse detection in follow-up studies of EBC. tissue_expression_up hsa-mir-129 Gastric Neoplasms 24969565 lncRNA-AC130710 targeting by miR-129-5p is upregulated in gastric cancer and associates with poor prognosis. tissue_expression_up hsa-mir-15a Macular Degeneration 24970617 The expression of several miRNAs related to angiogenesis and fibrosis was expressed significantly higher in the vitreous of eyes with PDR.Further studies are needed to understand the role played by the miRNAs in the biological function of the eye. tissue_expression_up hsa-mir-29a Macular Degeneration 24970617 The expression of several miRNAs related to angiogenesis and fibrosis was expressed significantly higher in the vitreous of eyes with PDR.Further studies are needed to understand the role played by the miRNAs in the biological function of the eye. tissue_expression_up hsa-mir-320a Macular Degeneration 24970617 The expression of several miRNAs related to angiogenesis and fibrosis was expressed significantly higher in the vitreous of eyes with PDR.Further studies are needed to understand the role played by the miRNAs in the biological function of the eye. tissue_expression_up hsa-mir-320b Macular Degeneration 24970617 The expression of several miRNAs related to angiogenesis and fibrosis was expressed significantly higher in the vitreous of eyes with PDR.Further studies are needed to understand the role played by the miRNAs in the biological function of the eye. tissue_expression_up hsa-mir-423 Macular Degeneration 24970617 The expression of several miRNAs related to angiogenesis and fibrosis was expressed significantly higher in the vitreous of eyes with PDR.Further studies are needed to understand the role played by the miRNAs in the biological function of the eye. tissue_expression_up hsa-mir-93 Macular Degeneration 24970617 The expression of several miRNAs related to angiogenesis and fibrosis was expressed significantly higher in the vitreous of eyes with PDR.Further studies are needed to understand the role played by the miRNAs in the biological function of the eye. tissue_expression_up hsa-mir-192 Gastric Neoplasms 24981590 These data suggest that frequently up-regulated miR-215/192 in gastric cancer may participate in gastric cancer progression. tissue_expression_up hsa-mir-215 Gastric Neoplasms 24981590 These data suggest that frequently up-regulated miR-215/192 in gastric cancer may participate in gastric cancer progression. tissue_expression_up hsa-mir-302f Breast Neoplasms 24982406 MiR-337 and miR-302f were commonly overexpressed in HER2-postive breast and gastric cancer. MiR-139 and miR-129 were commonly underexpressed in HER2-positive breast and gastric cancer. tissue_expression_up hsa-mir-155 Colon Neoplasms 24989910 The level of miR-155 was gradually elevated with the formation of colitis-associated colon cancer. tissue_expression_up hsa-mir-141 Chondrosarcoma 24992595 Paeonol suppresses chondrosarcoma metastasis through up-regulation of miR-141 by modulating PKC¦Ä and c-Src signaling pathway. tissue_expression_up hsa-mir-143 Chronic Hepatitis 24993656 "In conclusion, the expression of miR-143 and miR-215 in serum were significantly up-regulated in patients with chronic hepatitis and HCC. Due to its reasonable sensitivity and specificity for both diseases, miR-143 and miR-215 could be as potential circulating biomarkers." tissue_expression_up hsa-mir-215 Chronic Hepatitis 24993656 "In conclusion, the expression of miR-143 and miR-215 in serum were significantly up-regulated in patients with chronic hepatitis and HCC. Due to its reasonable sensitivity and specificity for both diseases, miR-143 and miR-215 could be as potential circulating biomarkers." tissue_expression_up hsa-mir-126 Asthma 24995087 "Compared to the normal group, miR-21 and miR-126 expression was significantly upregulated in asthma patients regardless of treatment." tissue_expression_up hsa-mir-141 "Carcinoma, Lung, Non-Small-Cell" 25003366 High miR-141 and miR-200c expression are associated with shorter OS in NSCLC patients with adenocarcinoma through MET and angiogenesis. tissue_expression_up hsa-mir-200c "Carcinoma, Lung, Non-Small-Cell" 25003366 High miR-141 and miR-200c expression are associated with shorter OS in NSCLC patients with adenocarcinoma through MET and angiogenesis. tissue_expression_up hsa-mir-758 Hepatitis C Virus Infection 25008898 Hepatitis C virus infection decreases the expression of Toll-like receptors 3 and 7 via upregulation of miR-758. tissue_expression_up hsa-mir-1288 Ectopic Pregnancy 25013942 "Microarray studies showed that four miRNAs were differentially downregulated (hsa-mir-196b, hsa-mir-30a, hsa-mir-873, and hsa-mir-337-3p) and three upregulated (hsa-mir-1288, hsa-mir-451, and hsa-mir-223) in EP compared to control tissue samples." tissue_expression_up hsa-mir-223 Ectopic Pregnancy 25013942 "Microarray studies showed that four miRNAs were differentially downregulated (hsa-mir-196b, hsa-mir-30a, hsa-mir-873, and hsa-mir-337-3p) and three upregulated (hsa-mir-1288, hsa-mir-451, and hsa-mir-223) in EP compared to control tissue samples." tissue_expression_up hsa-mir-451 Ectopic Pregnancy 25013942 "Microarray studies showed that four miRNAs were differentially downregulated (hsa-mir-196b, hsa-mir-30a, hsa-mir-873, and hsa-mir-337-3p) and three upregulated (hsa-mir-1288, hsa-mir-451, and hsa-mir-223) in EP compared to control tissue samples." tissue_expression_up hsa-mir-210 Preeclampsia 25015807 "This increases the expression of miR-210 in the placenta causing repression of mitochondria-associated target genes, potentially leading to mitochondrial and placental dysfunction." tissue_expression_up hsa-mir-145 Colorectal Carcinoma 25019299 Up-regulation of microRNA-145 associates with lymph node metastasis in colorectal cancer. tissue_expression_up hsa-mir-139 Breast Neoplasms 25027758 "Down-regulation of miR-486-5p and miR-139-5p, in conjunction with up-regulation of miR-21, may represent a useful signature for the identification of high-risk breast cancer patients." tissue_expression_up hsa-mir-21 Breast Neoplasms 25027758 "Down-regulation of miR-486-5p and miR-139-5p, in conjunction with up-regulation of miR-21, may represent a useful signature for the identification of high-risk breast cancer patients." tissue_expression_up hsa-mir-486 Breast Neoplasms 25027758 "Down-regulation of miR-486-5p and miR-139-5p, in conjunction with up-regulation of miR-21, may represent a useful signature for the identification of high-risk breast cancer patients." tissue_expression_up hsa-mir-630 Kidney Neoplasms 25031755 "The study proves for the first time that miR-630 is upregulated in a majority of ccRCC patients. It also shows that miR-630 expression is an independent prognostic factor for patients with renal cancer, which might be a potential valuable biomarker for ccRCC." tissue_expression_up hsa-mir-182 Colorectal Carcinoma 25031782 Increased expression of miRNA-182 in colorectal carcinoma: an independent and tissue-specific prognostic factor. tissue_expression_up hsa-mir-31 Kawasaki Syndrome 25039241 "These results suggest that the decrease in FoxP3(+) Treg might be associated with decreased expression of miR-155, leading to aberrant SOCS1/STAT-5 signalling and overexpression of miR-31 in patients with acute KD." tissue_expression_up hsa-mir-106b Medulloblastoma 25041637 These data suggested the upregulation of miR-106b in MB and the involvement of miR-106b in MB biology. tissue_expression_up hsa-mir-143 Sepsis 25043848 "Through microRNA microarray and qRT-PCR we found that the levels of miR-27a, miR-153 and miR-143 are up regulated, while let-7a, miR-218 and miR-129-5p are down regulated in lungs of septic mice." tissue_expression_up hsa-mir-34c Alzheimer Disease 25052764 "We have used an in vivo neonatal mouse model to induce ketamine-related neurotoxicity in the hippocampus, and found that miR-34c, a microRNA associated with pathogenesis of Alzheimer's disease, was significantly upregulated during ketamine-induced hippocampal neurodegeneration." tissue_expression_up hsa-let-7d HIV-Associated Lipodystrophy 25063777 "Eleven other miRNAs (i.e. miR-let-7d, miR-24, miR-30c, miR-125a-3p, miR-149, miR-191, miR-196-b, miR-218, miR-342-3p, miR-452 and miR-454*) were 2- to 2.5-fold more expressed in HIV+ samples than in controls." tissue_expression_up hsa-mir-125 HIV-Associated Lipodystrophy 25063777 "Eleven other miRNAs (i.e. miR-let-7d, miR-24, miR-30c, miR-125a-3p, miR-149, miR-191, miR-196-b, miR-218, miR-342-3p, miR-452 and miR-454*) were 2- to 2.5-fold more expressed in HIV+ samples than in controls." tissue_expression_up hsa-mir-125a HIV-Associated Lipodystrophy 25063777 "Eleven other miRNAs (i.e. miR-let-7d, miR-24, miR-30c, miR-125a-3p, miR-149, miR-191, miR-196-b, miR-218, miR-342-3p, miR-452 and miR-454*) were 2- to 2.5-fold more expressed in HIV+ samples than in controls." tissue_expression_up hsa-mir-149 HIV-Associated Lipodystrophy 25063777 "Eleven other miRNAs (i.e. miR-let-7d, miR-24, miR-30c, miR-125a-3p, miR-149, miR-191, miR-196-b, miR-218, miR-342-3p, miR-452 and miR-454*) were 2- to 2.5-fold more expressed in HIV+ samples than in controls." tissue_expression_up hsa-mir-186 HIV-Associated Lipodystrophy 25063777 "Ten of these (i.e. miR-186, miR-199a-3p, miR-214, miR-374a, miR-487b, miR-532-5p, miR-628-5p, miR-874, miR-125-b-1* and miR-374b*) were up-regulated to a significant degree" tissue_expression_up hsa-mir-191 HIV-Associated Lipodystrophy 25063777 "Eleven other miRNAs (i.e. miR-let-7d, miR-24, miR-30c, miR-125a-3p, miR-149, miR-191, miR-196-b, miR-218, miR-342-3p, miR-452 and miR-454*) were 2- to 2.5-fold more expressed in HIV+ samples than in controls." tissue_expression_up hsa-mir-196b HIV-Associated Lipodystrophy 25063777 "Eleven other miRNAs (i.e. miR-let-7d, miR-24, miR-30c, miR-125a-3p, miR-149, miR-191, miR-196-b, miR-218, miR-342-3p, miR-452 and miR-454*) were 2- to 2.5-fold more expressed in HIV+ samples than in controls." tissue_expression_up hsa-mir-199a HIV-Associated Lipodystrophy 25063777 "Ten of these (i.e. miR-186, miR-199a-3p, miR-214, miR-374a, miR-487b, miR-532-5p, miR-628-5p, miR-874, miR-125-b-1* and miR-374b*) were up-regulated to a significant degree" tissue_expression_up hsa-mir-214 HIV-Associated Lipodystrophy 25063777 "Ten of these (i.e. miR-186, miR-199a-3p, miR-214, miR-374a, miR-487b, miR-532-5p, miR-628-5p, miR-874, miR-125-b-1* and miR-374b*) were up-regulated to a significant degree" tissue_expression_up hsa-mir-218 HIV-Associated Lipodystrophy 25063777 "Eleven other miRNAs (i.e. miR-let-7d, miR-24, miR-30c, miR-125a-3p, miR-149, miR-191, miR-196-b, miR-218, miR-342-3p, miR-452 and miR-454*) were 2- to 2.5-fold more expressed in HIV+ samples than in controls." tissue_expression_up hsa-mir-24 HIV-Associated Lipodystrophy 25063777 "Eleven other miRNAs (i.e. miR-let-7d, miR-24, miR-30c, miR-125a-3p, miR-149, miR-191, miR-196-b, miR-218, miR-342-3p, miR-452 and miR-454*) were 2- to 2.5-fold more expressed in HIV+ samples than in controls." tissue_expression_up hsa-mir-30c HIV-Associated Lipodystrophy 25063777 "Eleven other miRNAs (i.e. miR-let-7d, miR-24, miR-30c, miR-125a-3p, miR-149, miR-191, miR-196-b, miR-218, miR-342-3p, miR-452 and miR-454*) were 2- to 2.5-fold more expressed in HIV+ samples than in controls." tissue_expression_up hsa-mir-342 HIV-Associated Lipodystrophy 25063777 "Eleven other miRNAs (i.e. miR-let-7d, miR-24, miR-30c, miR-125a-3p, miR-149, miR-191, miR-196-b, miR-218, miR-342-3p, miR-452 and miR-454*) were 2- to 2.5-fold more expressed in HIV+ samples than in controls." tissue_expression_up hsa-mir-374a HIV-Associated Lipodystrophy 25063777 "Ten of these (i.e. miR-186, miR-199a-3p, miR-214, miR-374a, miR-487b, miR-532-5p, miR-628-5p, miR-874, miR-125-b-1* and miR-374b*) were up-regulated to a significant degree" tissue_expression_up hsa-mir-374b HIV-Associated Lipodystrophy 25063777 "Ten of these (i.e. miR-186, miR-199a-3p, miR-214, miR-374a, miR-487b, miR-532-5p, miR-628-5p, miR-874, miR-125-b-1* and miR-374b*) were up-regulated to a significant degree" tissue_expression_up hsa-mir-452 HIV-Associated Lipodystrophy 25063777 "Eleven other miRNAs (i.e. miR-let-7d, miR-24, miR-30c, miR-125a-3p, miR-149, miR-191, miR-196-b, miR-218, miR-342-3p, miR-452 and miR-454*) were 2- to 2.5-fold more expressed in HIV+ samples than in controls." tissue_expression_up hsa-mir-454 HIV-Associated Lipodystrophy 25063777 "Eleven other miRNAs (i.e. miR-let-7d, miR-24, miR-30c, miR-125a-3p, miR-149, miR-191, miR-196-b, miR-218, miR-342-3p, miR-452 and miR-454*) were 2- to 2.5-fold more expressed in HIV+ samples than in controls." tissue_expression_up hsa-mir-487b HIV-Associated Lipodystrophy 25063777 "Ten of these (i.e. miR-186, miR-199a-3p, miR-214, miR-374a, miR-487b, miR-532-5p, miR-628-5p, miR-874, miR-125-b-1* and miR-374b*) were up-regulated to a significant degree" tissue_expression_up hsa-mir-532 HIV-Associated Lipodystrophy 25063777 "Ten of these (i.e. miR-186, miR-199a-3p, miR-214, miR-374a, miR-487b, miR-532-5p, miR-628-5p, miR-874, miR-125-b-1* and miR-374b*) were up-regulated to a significant degree" tissue_expression_up hsa-mir-628 HIV-Associated Lipodystrophy 25063777 "Ten of these (i.e. miR-186, miR-199a-3p, miR-214, miR-374a, miR-487b, miR-532-5p, miR-628-5p, miR-874, miR-125-b-1* and miR-374b*) were up-regulated to a significant degree" tissue_expression_up hsa-mir-874 HIV-Associated Lipodystrophy 25063777 "Ten of these (i.e. miR-186, miR-199a-3p, miR-214, miR-374a, miR-487b, miR-532-5p, miR-628-5p, miR-874, miR-125-b-1* and miR-374b*) were up-regulated to a significant degree" tissue_expression_up hsa-mir-92a Myocardial Infarction 25064220 miR-92a expression in ischemia-reperfusion group was significantly higher than in sham operation group tissue_expression_up hsa-mir-222 Bladder Neoplasms 25078265 Increased expression of miR-222 is associated with poor prognosis in bladder cancer. tissue_expression_up hsa-mir-190 Epstein-Barr Virus Infection 25086243 mir-190 is upregulated in Epstein-Barr Virus type I latency and modulates cellular mRNAs involved in cell survival and viral reactivation. tissue_expression_up hsa-mir-145 Malignant Neoplasms [unspecific] 25106061 "Our findings indicate that high miR-145 expression is better at predicting patient survival rather than disease progression for malignant tumors, especially for SCC and glioblastoma in Asians. Considering the insufficient evidence, further investigations and more studies are needed." tissue_expression_up hsa-mir-19a Bladder Neoplasms 25107371 Our data indicated that miR-19a might act as an oncogenic microRNA in bladder cancer and was significantly up-regulated in bladder cancer carcinogenesis. The oncogenic role of miR19a in bladder cancer was dependent on targeting PTEN. tissue_expression_up hsa-mir-106a Gastric Neoplasms 25115709 Similarly up-regulated microRNA-106a in matched formalin-fixed paraffin-embedded and fresh frozen samples and the dynamic changes during gastric carcinogenesis and development. tissue_expression_up hsa-mir-24 Breast Neoplasms 25120807 Over-expression of miR-24 and miR-378 in FFPE tissue of breast cancer patients might conduct as an ideal source for biomarker discovery and validation in breast cancer patients. tissue_expression_up hsa-mir-378a Breast Neoplasms 25120807 Over-expression of miR-24 and miR-378 in FFPE tissue of breast cancer patients might conduct as an ideal source for biomarker discovery and validation in breast cancer patients. tissue_expression_up hsa-mir-31 "Carcinoma, Gingival" 25126847 "Expression of hsa-miR-31 was significantly up-regulated in both cancer and leukoplakia tissues and, thus, may be one of the molecular markers of leukoplakia which may progress to gingivo-buccal cancer." tissue_expression_up hsa-mir-582 Prostate Neoplasms 25176332 Our results suggest that up-regulation of miR-582-5p contributes to an increase in the proliferation of prostate cancer cells under androgen deprived conditions. tissue_expression_up hsa-mir-146a Diabetic Nephropathy 25182190 "Taken together, these findings indicate that the increased expression of miR-155 and miR-146a in the DN patients and in the experimental DN animal models was found to contribute to inflammation-mediated glomerular endothelial injury." tissue_expression_up hsa-mir-155 Diabetic Nephropathy 25182190 "Taken together, these findings indicate that the increased expression of miR-155 and miR-146a in the DN patients and in the experimental DN animal models was found to contribute to inflammation-mediated glomerular endothelial injury." tissue_expression_up hsa-mir-140 Spinal Chordoma 25197358 "Over-expression of miR-140-3p is correlated with recurrence and tumor invasion, suggesting that miR-140-3p could be a new predictor for recurrence and prognosis in patients with spinal chordoma." tissue_expression_up hsa-mir-185 "Carcinoma, Renal Cell" 25217984 Elevated microRNA-185 is associated with high vascular endothelial growth factor receptor 2 expression levels and high microvessel density in clear cell renal cell carcinoma. tissue_expression_up hsa-mir-129 Colorectal Carcinoma 25218158 Piceatannol promotes apoptosis via up-regulation of microRNA-129 expression in colorectal cancer cell lines. tissue_expression_up hsa-mir-132 Glioma 25234714 Upregulation of miR-132 expression in glioma and its clinical significance. tissue_expression_up hsa-mir-7 Pancreatic Neoplasms 25256401 Curcumin inhibits cell growth and invasion through up-regulation of miR-7 in pancreatic cancer cells. tissue_expression_up hsa-mir-155 Rectal Neoplasms 25261908 Increase in the expression of miR-155 might represent a potential valuable marker for rectal carcinoma N and combined tumor-node-metastasis staging. tissue_expression_up hsa-mir-10a Breast Neoplasms 25266482 These findings indicate that higher expression of RUNX2 and miR-10a/b was associated with adverse outcome of breast cancer. Expression levels of RUNX2 and miR-10a/b individually or jointly are potential prognostic factors for predicting breast cancer recurrence. Data from in vitro studies support the notion that RUNX2 promoted cell motility by upregulating miR-10a/b. tissue_expression_up hsa-mir-10b Breast Neoplasms 25266482 These findings indicate that higher expression of RUNX2 and miR-10a/b was associated with adverse outcome of breast cancer. Expression levels of RUNX2 and miR-10a/b individually or jointly are potential prognostic factors for predicting breast cancer recurrence. Data from in vitro studies support the notion that RUNX2 promoted cell motility by upregulating miR-10a/b. tissue_expression_up hsa-mir-184 Glioma 25277131 miR-184 upregulation enhanced the malignant phenotype of human glioma cancer cells by reducing FIH-1 protein expression. tissue_expression_up hsa-mir-141 Bladder Neoplasms 25304156 Increased miR-141 expression is associated with diagnosis and favorable prognosis of patients with bladder cancer. tissue_expression_up hsa-mir-214 Pancreatic Neoplasms 25304377 "Thirteen miRNAs (miR-138, miR-195, miR-204, miR-216a, miR-217, miR-218, miR-802, miR-155, miR-214, miR-26a, miR-30b, miR-31, and miR-125) were enriched and two miRNAs (miR-451a and miR-4284) were depleted in the cyst fluids derived from invasive carcinomas." tissue_expression_up hsa-mir-218 Pancreatic Neoplasms 25304377 "Thirteen miRNAs (miR-138, miR-195, miR-204, miR-216a, miR-217, miR-218, miR-802, miR-155, miR-214, miR-26a, miR-30b, miR-31, and miR-125) were enriched and two miRNAs (miR-451a and miR-4284) were depleted in the cyst fluids derived from invasive carcinomas." tissue_expression_up hsa-mir-30b Pancreatic Neoplasms 25304377 "Thirteen miRNAs (miR-138, miR-195, miR-204, miR-216a, miR-217, miR-218, miR-802, miR-155, miR-214, miR-26a, miR-30b, miR-31, and miR-125) were enriched and two miRNAs (miR-451a and miR-4284) were depleted in the cyst fluids derived from invasive carcinomas." tissue_expression_up hsa-mir-301a Breast Neoplasms 25311065 Upregulation of miR-301a correlates with poor prognosis in triple-negative breast cancer. tissue_expression_up hsa-mir-137 Bladder Neoplasms 25330156 MicroRNA-137 upregulation increases bladder cancer cell proliferation and invasion by targeting PAQR3. tissue_expression_up hsa-mir-21 Breast Neoplasms 25337203 Prognostic and clinicopathological significance of microRNA-21 overexpression in breast cancer: a meta-analysis. tissue_expression_up hsa-mir-195 Cardiovascular Diseases [unspecific] 25339460 "The cardiac dysfunction of the rat with selenium deficiency was mainly associated with five upregulated miRNAs, which were miR-374, miR-16, miR-199a-5p, miR-195 and miR-30e*, and three downregulated miRNAs, which were miR-3571, miR-675 and miR-450a*." tissue_expression_up hsa-mir-30d Diabetic Cardiomyopathies 25341033 Our study revealed that mir-30d expression was substantially increased in streptozotocin (STZ)-induced diabetic rats and in high-glucose-treated cardiomyocytes as well. tissue_expression_up hsa-mir-128a "Carcinoma, Hepatocellular" 25345933 miR-128a is up-regulated in HCC and promotes HCC cell proliferation by targeting RND3. tissue_expression_up hsa-mir-31 Pleural Mesothelioma 25358615 Upregulation of microRNA-31 associates with a poor prognosis of malignant pleural mesothelioma with sarcomatoid component. tissue_expression_up hsa-mir-200a Ovarian Neoplasms 25374174 miR-200a overexpression in advanced ovarian carcinomas as a prognostic indicator. tissue_expression_up hsa-mir-196a Gastric Neoplasms 25374225 Association of miR-193b down-regulation and miR-196a up-regulation with clinicopathological features andprognosis in gastric cancer. tissue_expression_up hsa-mir-210 "Carcinoma, Lung, Non-Small-Cell" 25384507 "At the same time, miR-21 and miR-210 were upregulated by 53.3 and 66.6% in cancer tissue versus matched adjacent normal tissues, respectively." tissue_expression_up hsa-mir-141 Endometriosis 25386850 "We found five miRNAs specific to epithelial cells--miR-34c, miR-449a, miR-200a, miR-200b and miR-141 showing significantly higher expression in peritoneal endometriotic lesions compared to healthy peritoneal tissues." tissue_expression_up hsa-mir-200b Endometriosis 25386850 "We found five miRNAs specific to epithelial cells--miR-34c, miR-449a, miR-200a, miR-200b and miR-141 showing significantly higher expression in peritoneal endometriotic lesions compared to healthy peritoneal tissues." tissue_expression_up hsa-mir-143 Endometriosis 25408705 miR-143 was up-regulated in EC (p=0.000) compared to EN. tissue_expression_up hsa-mir-145 Endometriosis 25408705 The miR-145 was up-regulated in both EU (p=0.004) and EC (p=0.000) in compared to EN group. tissue_expression_up hsa-mir-194 Gastric Neoplasms 25412959 "miR-194 overexpression or RBX1 lowexpression was associated with prolonged survival of GC patients. In conclusion, upregulation of miR-194 can inhibit proliferation, migration, and invasion of GC cells, possibly by targeting RBX1. Aberrant expression of miR-194 and RBX1 is correlated to GC patient survival time." tissue_expression_up hsa-mir-18a Gastric Neoplasms 25416437 "miR-18a may be a promising biomarker for the detection of gastric cancer and its upregulation may be potentially associated with unfavorable prognosis of bladder cancer, suggesting that miR-18a might serve as a potential biological marker for further risk stratification in the management of gastric cancer." tissue_expression_up hsa-mir-224 Colorectal Adenocarcinoma 25420464 "miR-224 is significantly upregulated in malignant colorectal tumors compared to adjacent non-cancer mucosae, and its enhanced expression constitutes an independent predictor of short-term relapse and poor overall survival in colorectal adenocarcinoma patients." tissue_expression_up hsa-mir-221 Glioma 25428536 "There are a series of abnormal miRNA expressions in glioma. Among them, miR-221 and miR -222 are clustered miR s with elevated expressions. The over-expressions of miR-221 and miR-222 can be considered as new molecular tags for human glioma (Tab. 5, Fig. 4, Ref. 30)." tissue_expression_up hsa-mir-222 Glioma 25428536 "There are a series of abnormal miRNA expressions in glioma. Among them, miR-221 and miR -222 are clustered miR s with elevated expressions. The over-expressions of miR-221 and miR-222 can be considered as new molecular tags for human glioma (Tab. 5, Fig. 4, Ref. 30)." tissue_expression_up hsa-mir-21 Breast Neoplasms 25440114 "the context of altered miR-21 expression provides clinically relevant information. Importantly, miR-21 expression was predominantly up-regulated and potentially prognostic in the tumor stroma of TNBC." tissue_expression_up hsa-mir-145 Aortic Aneurysm 25465469 The increased expression of microRNA-145 promotes media remodeling through TGF-b1 in the aortic aneurysm wall. tissue_expression_up hsa-mir-106b "Carcinoma, Hepatocellular" 25466449 miR-106b expression was significantly upregulated in HCC and could serve as a potential unfavorable prognostic biomarker. tissue_expression_up hsa-mir-21 "Squamous Cell Carcinoma, Oral" 25482863 "Our results corroborate the previous findings on the overexpression of mir-21 and downregulation of miR-138 in OSCC. As the expression of miR-184 is controversial in tongue/oral cancer, the downregulation may be specific to tumor anatomical localization. On the other hand, to the best of our knowledge, this is the first report to show the association of miR-155 with tobacco chewing and the downregulation of miR-125b-2* in OSCC. Computational predictions suggest that miR-125b-2* may have a role in alternative splicing." tissue_expression_up hsa-mir-146a Diabetes Mellitus 25490205 abnormal miR-146a upregulation may be an important mechanism of delayed wound healing in the diabetic cornea. tissue_expression_up hsa-mir-125b Glioma 25502291 "Higher expressions of miR-125b and miR-222 have also been proved to be associated with glioma. Furthermore, glioma patients with higher miR-125b, miR-221, and miR-222 expression were manifested to have poorer prognostic status, which might be attributed to their attenuated sensitivity to chemotherapy and radiotherapy." tissue_expression_up hsa-mir-221 Glioma 25502291 "Higher expressions of miR-125b and miR-222 have also been proved to be associated with glioma. Furthermore, glioma patients with higher miR-125b, miR-221, and miR-222 expression were manifested to have poorer prognostic status, which might be attributed to their attenuated sensitivity to chemotherapy and radiotherapy." tissue_expression_up hsa-mir-222 Glioma 25502291 "Higher expressions of miR-125b and miR-222 have also been proved to be associated with glioma. Furthermore, glioma patients with higher miR-125b, miR-221, and miR-222 expression were manifested to have poorer prognostic status, which might be attributed to their attenuated sensitivity to chemotherapy and radiotherapy." tissue_expression_up hsa-mir-10b Neoplasms [unspecific] 25510966 high-expression of microRNA-10b can predict worse outcomes in some types of cancer and the regular monitoring of miR-10b expression might be useful in the clinical practice. tissue_expression_up hsa-mir-374b Gastric Neoplasms 25516656 upregulation of miR-374b-5p contributes to gastric cancer cell metastasis and invasion through inhibition of RECK expression. tissue_expression_up hsa-mir-146a "Carcinoma, Thyroid" 25524940 Up-regulation of miR-146a and miR-146b expression in tissues was related to carcinogenesis and deterioration of PTC. MicroRNA-146a and miR-146b expressed in thyroid tissue may act as potential biomarkers for PTC patients. tissue_expression_up hsa-mir-146b "Carcinoma, Thyroid" 25524940 Up-regulation of miR-146a and miR-146b expression in tissues was related to carcinogenesis and deterioration of PTC. MicroRNA-146a and miR-146b expressed in thyroid tissue may act as potential biomarkers for PTC patients. tissue_expression_up hsa-mir-143 Osteosarcoma 25562163 "TGF-¦Â1 up-regulates versican expression bysuppressing miR-143, and this pathway is important for osteosarcoma cell migration and invasion." tissue_expression_up hsa-mir-21 "Carcinoma, Colon" 25569638 the primary tumor in colon cancer releases high concentrations of miR-21 in the MV but that these concentrations are later diluted in the circulatory system. MV expression of miR-21 may be a stronger prognostic marker than PV expression. tissue_expression_up hsa-mir-210 Glioblastoma 25586423 Acute hypoxia induces upregulation of microRNA-210 expression in glioblastoma spheroids. tissue_expression_up hsa-mir-142 Atherosclerosis 25586666 the upregulation of miR-142-5p expression may regulate apoptosis in human macrophages by targeting TGF-¦Â2. This effect may have an important role in the progression of atherosclerosis. tissue_expression_up hsa-mir-196a Osteosarcoma 25599934 the effects of miR-196a over-expression on tumour cell response may be strictly related to species and cell type. Further studies are needed to define the impact of miRNA deregulation on OS development. tissue_expression_up hsa-mir-155 Lung Neoplasms 25603615 The current paper on Meta-analysis demonstrated a correlation between the high expression of miRNA-155 and the outcome of patients with non-small cell lung cancer. tissue_expression_up hsa-mir-125b Breast Neoplasms 25605244 up-regulation of miR-125b or targeting Sema4C could serve as novel approaches to reverse chemotherapy resistance in breast cancers. tissue_expression_up hsa-mir-34a Osteonecrosis 25612520 The expression of miR-34a and miR-146a and genes in the predict pathways were significantly up-regulated. tissue_expression_up hsa-mir-132 "Leukemia, Lymphocytic, Chronic, B-Cell" 25645730 Increased chronic lymphocytic leukemia proliferation upon IgM stimulation is sustained by the upregulation of miR-132 and miR-212. tissue_expression_up hsa-mir-212 "Leukemia, Lymphocytic, Chronic, B-Cell" 25645730 Increased chronic lymphocytic leukemia proliferation upon IgM stimulation is sustained by the upregulation of miR-132 and miR-212. tissue_expression_up hsa-mir-92a Colorectal Adenocarcinoma 25663865 A statistically significant difference was observed between the expression levels of miR-92a in CA and the paralesional normal controls. tissue_expression_up hsa-mir-199 Irritable Bowel Syndrome 25681400 Decreased miR-199 augments visceral pain in patients with IBS through translational upregulation of TRPV1. tissue_expression_up hsa-mir-21 Ischemia-Reperfusion Injury 25691473 miR-21 has been shown to be enriched in kidney tissue in mice and humans with acute kidney injury tissue_expression_up hsa-mir-218 Gastric Neoplasms 25694126 Thermo-chemotherapy Induced miR-218 upregulation inhibits the invasion of gastric cancer via targeting Gli2 and E-cadherin. tissue_expression_up hsa-mir-1280 "Carcinoma, Lung, Non-Small-Cell" 25698202 The miR-1280 expression was significantly higher in the NSCLC tissues than distal normal tissues tissue_expression_up hsa-mir-141 Bladder Neoplasms 25703910 "There was a more expression rate of miR-200c, miR-141 and miR-30b in bladder cancer tissues than healthy adjacent control tissues. Further studies are needed to draw final conclusion." tissue_expression_up hsa-mir-200c Bladder Neoplasms 25703910 "There was a more expression rate of miR-200c, miR-141 and miR-30b in bladder cancer tissues than healthy adjacent control tissues. Further studies are needed to draw final conclusion." tissue_expression_up hsa-mir-30b Bladder Neoplasms 25703910 "There was a more expression rate of miR-200c, miR-141 and miR-30b in bladder cancer tissues than healthy adjacent control tissues. Further studies are needed to draw final conclusion." tissue_expression_up hsa-mir-21 Multiple Myeloma 25704079 EBV could further exacerbate the disease by inducing miR-21 tissue_expression_up hsa-mir-146b Atherosclerosis 25743474 Aa challenge significantly increased the expression of miR-146b and miR-155 in the aorta. tissue_expression_up hsa-mir-181b Adenovirus Infection 25744056 The expression patterns of these miRNAs changed dramatically during the course of the infection tissue_expression_up hsa-mir-191 Adenovirus Infection 25744056 The expression patterns of these miRNAs changed dramatically during the course of the infection tissue_expression_up hsa-mir-21 "Adenocarcinoma, Esophageal" 25746664 "miRs such as miR-192, miR-196 and miR-21 were frequently noted to up-regulated whereas miR-203, miR-205 and miR-let-7 were commonly down-regulated during the development of Barrett's oesophagus to oesophageal adenocarcinoma." tissue_expression_up hsa-mir-503 "Carcinoma, Esophageal" 25750296 High miR-503 expression was identified as an independent prognostic predictor in patients with EC according to multivariate analysis tissue_expression_up hsa-mir-146b Gastroduodenal Ulcer 25753878 "This study indicated that the up-regulation of miR-155 and miR-146b decreases H. pylori (cagA+)-introduced IL6 overexpression, which might weaken the cleanup of H. pylori (cagA+) and contributes to ulcer." tissue_expression_up hsa-mir-155 Gastroduodenal Ulcer 25753878 "This study indicated that the up-regulation of miR-155 and miR-146b decreases H. pylori (cagA+)-introduced IL6 overexpression, which might weaken the cleanup of H. pylori (cagA+) and contributes to ulcer." tissue_expression_up hsa-mir-150 "Carcinoma, Lung, Non-Small-Cell" 25755784 Our data indicated that overexpression of miR-150 in NSCLC tissues has prognostic value. tissue_expression_up hsa-mir-10b Glioma 25773393 Correlation of microRNA-10b upregulation and poor prognosis in human gliomas. tissue_expression_up hsa-mir-1246 "Squamous Cell Carcinoma, Oral" 25791131 High miR-1246 expression is associated with poor prognosis in OSCC and may serve as a novel prognostic marker in OSCC. tissue_expression_up hsa-mir-125b Mesial Temporal Lobe Epilepsy 25801837 "In TLE patients, miR-183, miR- 135a, miR-125b, miR-30c and miR-27a were upregulated, whereas miR-128 was downregulated." tissue_expression_up hsa-mir-183 Mesial Temporal Lobe Epilepsy 25801837 "In TLE patients, miR-183, miR- 135a, miR-125b, miR-30c and miR-27a were upregulated, whereas miR-128 was downregulated." tissue_expression_up hsa-mir-24 Hyperglycemia 25814526 Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor. tissue_expression_up hsa-let-7g Follicular Atresia 25824548 let-7g was highly expressed during follicle atresia tissue_expression_up hsa-mir-200c "Carcinoma, Renal Cell" 25860934 Loss of miR-200c up-regulates CYP1B1 and confers docetaxel resistance in renal cell carcinoma. tissue_expression_up hsa-let-7a "Squamous Cell Carcinoma, Head and Neck" 25862914 The microRNA profile seems to play a potential role in the pathobiology of oropharyngeal and laryngeal HNSCC. Up-regulation of miR34a in p16-positive oropharyngeal cancer has not been so far described and additional studies are warranted. tissue_expression_up hsa-mir-200c "Squamous Cell Carcinoma, Head and Neck" 25862914 The microRNA profile seems to play a potential role in the pathobiology of oropharyngeal and laryngeal HNSCC. Up-regulation of miR34a in p16-positive oropharyngeal cancer has not been so far described and additional studies are warranted. tissue_expression_up hsa-mir-21 "Squamous Cell Carcinoma, Head and Neck" 25862914 The microRNA profile seems to play a potential role in the pathobiology of oropharyngeal and laryngeal HNSCC. Up-regulation of miR34a in p16-positive oropharyngeal cancer has not been so far described and additional studies are warranted. tissue_expression_up hsa-mir-34a "Squamous Cell Carcinoma, Head and Neck" 25862914 The microRNA profile seems to play a potential role in the pathobiology of oropharyngeal and laryngeal HNSCC. Up-regulation of miR34a in p16-positive oropharyngeal cancer has not been so far described and additional studies are warranted. tissue_expression_up hsa-mir-375 "Squamous Cell Carcinoma, Head and Neck" 25862914 The microRNA profile seems to play a potential role in the pathobiology of oropharyngeal and laryngeal HNSCC. Up-regulation of miR34a in p16-positive oropharyngeal cancer has not been so far described and additional studies are warranted. tissue_expression_up hsa-mir-125a Autoimmune Thyroiditis 25863684 Decreased expression of microRNA-125a-3p upregulates interleukin-23 receptor in patients with Hashimoto's thyroiditis. tissue_expression_up hsa-mir-155 Atherosclerosis 25872580 "our data demonstrate that miR-155 is significantly upregulated in atherosclerotic plaque, functioning to accelerate the proliferation and migration of VSMCs by targeting eNOS." tissue_expression_up hsa-mir-375 Diabetes Mellitus 25875172 "These findings support an important role of miR-375 in regulation of human ¦Â-cell phenotype, and suggest that miR-375 upregulation may facilitate the generation of functional insulin-producing cells following ex-vivo expansion of human islet cells." tissue_expression_up hsa-mir-155 Waldenstrom Macroglobulinemia 25893290 "In two cell lines, miR-155 upregulation, which is common in WM, was responsible for the inhibition of FOXO3a and Bim expression." tissue_expression_up hsa-mir-20b "Carcinoma, Breast" 25893380 miR-20b is up-regulated in brain metastases from primary breast cancers. tissue_expression_up hsa-mir-10b Endometriosis 25896413 miR-10b directly targets ZEB1 and PIK3CA to curb adenomyotic epithelial cell invasiveness via upregulation of E-Cadherin and inhibition of Akt phosphorylation. tissue_expression_up hsa-mir-21 Myocardial Infarction 25896982 "Compared to sham group, we found a twofold increase in the cardiac expression of microRNA-21 and 0.5-fold decrease in microRNA-29b in heart tissue from vehicle-treated MI." tissue_expression_up hsa-mir-9 Osteoarthritis 25917063 These findings implicate miR-9-mediated suppression of MCPIP-1 in the pathogenesis of OA via up-regulation of IL-6 expression in IL-1¦Â-stimulated human OA chondrocytes. tissue_expression_up hsa-mir-122 Human Immunodeficiency Virus Infection 25920531 "our results revealed that the Vpr-upregulated expression of miR-122 is closely related to the stimulation of HCV 5' UTR activity and HCV replication by Vpr, providing new evidence for how HIV interacts with HCV during HIV/HCV co-infection." tissue_expression_up hsa-mir-221 Inflammation 25926893 "Interestingly, miR-221 (2-fold, Pâ€?â€?.002), miR-222 (2.5-fold, Pâ€?â€?.04), and miR-155 (5-fold, Pâ€?â€?.015) were increased in inflamed adipocytes" tissue_expression_up hsa-mir-222 Inflammation 25926893 "Interestingly, miR-221 (2-fold, Pâ€?â€?.002), miR-222 (2.5-fold, Pâ€?â€?.04), and miR-155 (5-fold, Pâ€?â€?.015) were increased in inflamed adipocytes" tissue_expression_up hsa-mir-15a Cataract 25932180 "hsa-miR-15a-5p, hsa-miR-15a-3p, and hsa-miR-16-1-5p were expressed at low levels in normal lens epithelial cells but at significantly higher levels in corresponding cells of patients" tissue_expression_up hsa-mir-221 Colon Neoplasms 25932237 "high expression of miR-211 (HR=2.394, 95% CI: 1.210-4.910, P=0.006) were identified as risk factors for colon cancer prognosis" tissue_expression_up hsa-mir-155 Prostate Neoplasms 25938433 "hsa-miR-155, hsa-miR-141 and hsa-miR-21 gene expressions were significantly elevated (66-85%, P<0.05) in tumor specimens" tissue_expression_up hsa-mir-328 "Leukemia, Myeloid, Chronic" 25948184 "miR-328 has been successfully constructed and transfected into K562 cells, miR-328 inhibits the proliferation of K562 cells by up-regulation of C/EBP¦Á." tissue_expression_up hsa-mir-21 "Adenocarcinoma, Esophageal" 25950983 microRNA-21 expression is elevated in esophageal adenocarcinoma after neoadjuvant chemotherapy. tissue_expression_up hsa-mir-182 Prostate Neoplasms 25977730 MicroRNA expression profiling in primary PCa and morphological normal prostate (MNPT) tissues identified 17 miRNAs significantly overexpressed in PCa. tissue_expression_up hsa-mir-15a Asthma 25979194 miRNA regulation network demonstrated that miR-16 and miR-15a had higher degree. tissue_expression_up hsa-mir-16 Asthma 25979194 miRNA regulation network demonstrated that miR-16 and miR-15a had higher degree. tissue_expression_up hsa-mir-34a Melanoma 25982144 Real-time PCR analysis showed 14-fold increase of miR-34a expression in the SDT group compared to the control group tissue_expression_up hsa-mir-141 Colorectal Carcinoma 25989926 "A set of three specific fecal miRNAs is overexpressed before surgery, and return within the normal range after cancer removal could be considered as an appealing opportunity for a new reliable tool for CRC secondary prevention. However, their role needs to be explored in large prospective trials and compared with the existing screening tools." tissue_expression_up hsa-mir-16 Colorectal Carcinoma 25989926 "A set of three specific fecal miRNAs is overexpressed before surgery, and return within the normal range after cancer removal could be considered as an appealing opportunity for a new reliable tool for CRC secondary prevention. However, their role needs to be explored in large prospective trials and compared with the existing screening tools." tissue_expression_up hsa-mir-19b Colorectal Carcinoma 25989926 "A set of three specific fecal miRNAs is overexpressed before surgery, and return within the normal range after cancer removal could be considered as an appealing opportunity for a new reliable tool for CRC secondary prevention. However, their role needs to be explored in large prospective trials and compared with the existing screening tools." tissue_expression_up hsa-mir-20a Colorectal Carcinoma 25989926 "A set of three specific fecal miRNAs is overexpressed before surgery, and return within the normal range after cancer removal could be considered as an appealing opportunity for a new reliable tool for CRC secondary prevention. However, their role needs to be explored in large prospective trials and compared with the existing screening tools." tissue_expression_up hsa-mir-21 Colorectal Carcinoma 25989926 "A set of three specific fecal miRNAs is overexpressed before surgery, and return within the normal range after cancer removal could be considered as an appealing opportunity for a new reliable tool for CRC secondary prevention. However, their role needs to be explored in large prospective trials and compared with the existing screening tools." tissue_expression_up hsa-mir-92a Colorectal Carcinoma 25989926 "A set of three specific fecal miRNAs is overexpressed before surgery, and return within the normal range after cancer removal could be considered as an appealing opportunity for a new reliable tool for CRC secondary prevention. However, their role needs to be explored in large prospective trials and compared with the existing screening tools." tissue_expression_up hsa-mir-141 Bladder Neoplasms 25991007 The present meta-analysis identified eight highly significant and consistently dysregulated miRNAs from 19 datasets. We also constructed an eight-miRNA signature which provided predictive and prognostic value that complements traditional clinicopathological risk factors. tissue_expression_up hsa-mir-200c Bladder Neoplasms 25991007 The present meta-analysis identified eight highly significant and consistently dysregulated miRNAs from 19 datasets. We also constructed an eight-miRNA signature which provided predictive and prognostic value that complements traditional clinicopathological risk factors. tissue_expression_up hsa-mir-21 Bladder Neoplasms 25991007 The present meta-analysis identified eight highly significant and consistently dysregulated miRNAs from 19 datasets. We also constructed an eight-miRNA signature which provided predictive and prognostic value that complements traditional clinicopathological risk factors. tissue_expression_up hsa-mir-146a "Carcinoma, Thyroid, Papillary" 26003825 "Our results demonstrate that down-regulation of THR¦Â is a common feature of PTCs. While it is not associated with a more aggressive phenotype of PTC, it correlates with the reduction of all the markers of differentiation and is associated with overexpression of some miRNAs supposed to play a role in thyroid tumorigenesis." tissue_expression_up hsa-mir-21 "Carcinoma, Thyroid, Papillary" 26003825 "Our results demonstrate that down-regulation of THR¦Â is a common feature of PTCs. While it is not associated with a more aggressive phenotype of PTC, it correlates with the reduction of all the markers of differentiation and is associated with overexpression of some miRNAs supposed to play a role in thyroid tumorigenesis." tissue_expression_up hsa-mir-221 "Carcinoma, Thyroid, Papillary" 26003825 "Our results demonstrate that down-regulation of THR¦Â is a common feature of PTCs. While it is not associated with a more aggressive phenotype of PTC, it correlates with the reduction of all the markers of differentiation and is associated with overexpression of some miRNAs supposed to play a role in thyroid tumorigenesis." tissue_expression_up hsa-mir-21 Neoplasms [unspecific] 26032086 "miR-21, miR-148a, miR-505, and miR-1207-5p were found to be upregulated in growth factors-induced EMT process" tissue_expression_up hsa-mir-132 "Leukemia, Lymphocytic, Chronic, B-Cell" 26036258 The SIRT1/TP53 axis is activated upon B-cell receptor triggering via miR-132 up-regulation in chronic lymphocytic leukemia cells. tissue_expression_up hsa-mir-32 Lung Neoplasms 26036635 Tanshinones suppress AURKA through up-regulation of miR-32 expression in non-small cell lung cancer. tissue_expression_up hsa-mir-141 "Carcinoma, Endometrial" 26045795 miR-200a/miR-141 and miR-205 upregulation might be associated with hormone receptor status and prognosis in endometrial carcinomas. tissue_expression_up hsa-mir-200a "Carcinoma, Endometrial" 26045795 miR-200a/miR-141 and miR-205 upregulation might be associated with hormone receptor status and prognosis in endometrial carcinomas. tissue_expression_up hsa-mir-205 "Carcinoma, Endometrial" 26045795 miR-200a/miR-141 and miR-205 upregulation might be associated with hormone receptor status and prognosis in endometrial carcinomas. tissue_expression_up hsa-mir-1 Acute Myocardial Infarction 26046358 "This study highlights the stability of miRNAs after death and long-term fixation, validating their use as reliable biomarkers for AMI during postmortem examination." tissue_expression_up hsa-mir-208b Acute Myocardial Infarction 26046358 "This study highlights the stability of miRNAs after death and long-term fixation, validating their use as reliable biomarkers for AMI during postmortem examination." tissue_expression_up hsa-mir-196a Breast Neoplasms 26062455 MicroRNA-196a post-transcriptionally upregulates the UBE2C proto-oncogene and promotes cell proliferation in breast cancer. tissue_expression_up hsa-mir-182 Neoplasms [unspecific] 26063957 "High miR-182 expression is associated with poor OS and DFS/RFS/RFI in some types of cancers, and miR-182 may be a useful prognostic biomarker for predicting cancer prognosis. However, given the current insufficient relevant data, further clinical studies are needed." tissue_expression_up hsa-mir-197 Glioblastoma 26081814 FUS1 acts as a tumor-suppressor gene by upregulating miR-197 in human glioblastoma. tissue_expression_up hsa-mir-21 Myocardial Ischemic-Reperfusion Injury 26097555 "this study revealed the mechanism that TMZ up-regulated miR-21 expression, then miR-21 targeted PTEN increasing the PI3K pathway and finally the activation of this pathway counteracted the apoptotic effect of hypoxia/reperfusion." tissue_expression_up hsa-mir-124 "Carcinoma, Gastric" 26109806 Paeoniflorin inhibits human gastric carcinoma cell proliferation through up-regulation of microRNA-124 and suppression of PI3K/Akt and STAT3 signaling. tissue_expression_up hsa-mir-146b Myeloproliferative Neoplasms 26116595 Up-regulation of MicroRNA 146b is Associated with Myelofibrosis in Myeloproliferative Neoplasms. tissue_expression_up hsa-mir-218 Glioma 26133092 Propofol suppresses proliferation and invasion of glioma cells by upregulating microRNA-218 expression. tissue_expression_up hsa-mir-190b Breast Neoplasms 26141719 "This study reveals miR-190b as the highest up-regulated miRNA in hormone-dependent breast cancers. Due to its specificity and high expression level, miR-190b could therefore represent a new biomarker in hormone-dependent breast cancers but its exact role carcinogenesis remains to elucidate." tissue_expression_up hsa-mir-211 Colorectal Carcinoma 26152286 MicroRNA 211 expression is upregulated and associated with poor prognosis in colorectal cancer: a case-control study. tissue_expression_up hsa-mir-372 "Carcinoma, Oral" 26152520 Upregulation of miR-372 and -373 associates with lymph node metastasis and poor prognosis of oral carcinomas. tissue_expression_up hsa-mir-373 "Carcinoma, Oral" 26152520 Upregulation of miR-372 and -373 associates with lymph node metastasis and poor prognosis of oral carcinomas. tissue_expression_up hsa-mir-126 Heart Failure 26162916 "RV failure in PAH is associated with a specific molecular signature within the RV, contributing to a decrease in RV vascular density and promoting the progression to RV failure. More importantly, miR-126 upregulation in the RV improves microvessel density and RV function in experimental PAH." tissue_expression_up hsa-mir-183 "Adenocarcinoma, Lung" 26170125 down-regulation of miR-34c and up-regulation of miR-183 and miR-210 were identified in caner groups tissue_expression_up hsa-mir-210 "Adenocarcinoma, Lung" 26170125 down-regulation of miR-34c and up-regulation of miR-183 and miR-210 were identified in caner groups tissue_expression_up hsa-mir-34 Neoplasms [unspecific] 26177460 miR-34a overexpression leads to variable effects on p53 levels in p53-sufficient human cancer cell lines. tissue_expression_up hsa-mir-34a Neoplasms [unspecific] 26177460 miR-34a overexpression leads to variable effects on p53 levels in p53-sufficient human cancer cell lines. tissue_expression_up hsa-mir-21 Ischemia-Reperfusion Injury 26178499 Renal expressions of miR-21 and miR-106a were significantly elevated in ischemia 20 min and 30 min groups at 12 h and 24 h post-reperfusion tissue_expression_up hsa-mir-21 Coronary Artery Disease 26183619 miR-21 expression was increased in human tissue samples from patients with ISR compared with coronary artery disease specimen tissue_expression_up hsa-mir-15b Glioma 26191187 Up-regulation of microRNA-15b correlates with unfavorable prognosis and malignant progression of human glioma. tissue_expression_up hsa-mir-184 Lung Neoplasms 26199015 miRNA-197 and miRNA-184 are overexpressed in EGFR-mutant patients with BM and they might be a new biomarker for stratifying the risk of BM in this subpopulation. tissue_expression_up hsa-mir-1298 Vascular Disease [unspecific] 26199195 Keep calm and carry on: miR-1298 prevents up-regulation of Cx43 and secures a quiescent vascular smooth muscle cell. tissue_expression_up hsa-mir-184 Sebaceous Carcinoma 26203913 "Serial testing and validation confirmed overexpression of 2 miRNAs previously reported to be oncogenic, miR-486-5p (4.4-fold; Pâ€?â€?.4 ×â€?0-8) and miR-184 (3.5-fold; Pâ€?â€?.7 ×â€?0-6)" tissue_expression_up hsa-mir-21 Gastric Neoplasms 26209976 "It seems that miR-21 and miR-221 expression pattern in Iranian patients with gastric cancer are similar to any other population. Considering the increased expression level of two miRNAs in cancerous tissue compared to normal tissue as well as the area under ROC curve, miR-21 and miR-221 can be used for early detection of gastric cancer." tissue_expression_up hsa-mir-221 Gastric Neoplasms 26209976 "It seems that miR-21 and miR-221 expression pattern in Iranian patients with gastric cancer are similar to any other population. Considering the increased expression level of two miRNAs in cancerous tissue compared to normal tissue as well as the area under ROC curve, miR-21 and miR-221 can be used for early detection of gastric cancer." tissue_expression_up hsa-mir-206 Preeclampsia 26213997 Our pilot study has identified miRNA-206 as a novel factor upregulated in preeclampsia within the maternal circulation and in placental tissue. tissue_expression_up hsa-mir-133a Pancreatic Neoplasms 26214431 Propofol suppresses proliferation and invasion of pancreatic cancer cells by upregulating microRNA-133a expression. tissue_expression_up hsa-mir-17 "Leukemia-Lymphoma, Adult T-Cell" 26231295 Upregulation of miRNA-17 and miRNA-19 is associated with unfavorable prognosis in patients with T-cell lymphoblastic lymphoma. tissue_expression_up hsa-mir-19 "Leukemia-Lymphoma, Adult T-Cell" 26231295 Upregulation of miRNA-17 and miRNA-19 is associated with unfavorable prognosis in patients with T-cell lymphoblastic lymphoma. tissue_expression_up hsa-mir-210 Neoplasms [unspecific] 26239498 MicroRNA-210 is upregulated by hypoxia-inducible factor-1¦Á in the stromal cells of giant cell tumors of bone. tissue_expression_up hsa-mir-130b Glioblastoma 26241672 Upregulation of miR-130b enhances stem cell-like phenotype in glioblastoma by inactivating the Hippo signaling pathway. tissue_expression_up hsa-mir-21 Myocardial Infarction 26253453 "Compared with the CON group, miR-1 was downregulated, whereas miR-21 was upregulated, and BCL2 messenger RNA (mRNA) was upregulated, whereas BAX mRNA and programmed cell death 4 mRNA remained unchanged in the IPO group." tissue_expression_up hsa-let-7b Obesity 26258540 "Specifically, miR-28, miR-26, and let-7b previously shown to inhibit sex steroid production in human granulosa cells, were up-regulated." tissue_expression_up hsa-mir-221 "Carcinoma, Hepatocellular" 26258795 MiR-221 and miR-222 (miR-221/222) are well-studied oncogenic microRNAs that are frequently upregulated in several types of human tumors tissue_expression_up hsa-mir-221 Choriocarcinoma 26258795 MiR-221 and miR-222 (miR-221/222) are well-studied oncogenic microRNAs that are frequently upregulated in several types of human tumors tissue_expression_up hsa-mir-196a Glioma 26261539 Our results suggested that both high-miR-196a and low-miR-367 expression may be associated with aggressive progression and unfavorable clinical outcome in glioma patients. And combination of high-miR-196a and low-miR-367 expression may be a novel biomarker in identifying a poor prognosis group of high-grade glioma. tissue_expression_up hsa-mir-155 Colorectal Carcinoma 26261588 "miR-155-5p expression is up-regulated in most CRC and promotes proliferation, invasion and metastasis of CRC cells. It may play an essential role in tumorigenesis and tumor progression of CRC." tissue_expression_up hsa-mir-21 "Carcinoma, Cervical" 26261606 "MiR-21 upregulation is associated with aggressive progression and poor prognosis in cervical cancer, which suggests that miR-21 might be identified as an independent marker for predicting the clinical outcome of cervical cancer patients." tissue_expression_up hsa-mir-21 "Carcinoma, Hepatocellular" 26261620 Our results suggested that increased expression of miR-21 was significantly correlated with tumor progression and could be a novel potential biomarker for HCC prognosis. tissue_expression_up hsa-mir-122 Hepatitis C Virus Infection 26272127 The levels of miR-122 were higher in liver than those in blood from individuals infected with HCV genotypes 1 and 3 tissue_expression_up hsa-mir-125b "Fatty Liver, Non-Alcoholic" 26272872 Our findings identify a novel mechanism by which estrogen protects against hepatic steatosis in female mice via upregulating miR-125b expression. tissue_expression_up hsa-mir-20a "Carcinoma, Adenoid Cystic" 26293217 Increased expression of miR-17 and miR-20a was found in bACCs compared with bNs tissue_expression_up hsa-mir-146a Systemic Lupus Erythematosus 26315540 "Type I IFN inhibits the maturation of miR-146a through the up-regulation of MCPIP-1, and thus contributes to the uncontrolled inflammation and excessive inflammatory gene expression in SLE." tissue_expression_up hsa-mir-146b Atrial Fibrillation 26319023 "Expression of inflammation-associated miRNAs is significantly up-regulated in the left atrial appendage of patients with non-valvular paroxysmal atrial fibrillation, which may play a significant role in electrical and structural remodeling." tissue_expression_up hsa-mir-155 Atrial Fibrillation 26319023 "Expression of inflammation-associated miRNAs is significantly up-regulated in the left atrial appendage of patients with non-valvular paroxysmal atrial fibrillation, which may play a significant role in electrical and structural remodeling." tissue_expression_up hsa-mir-19b Atrial Fibrillation 26319023 "Expression of inflammation-associated miRNAs is significantly up-regulated in the left atrial appendage of patients with non-valvular paroxysmal atrial fibrillation, which may play a significant role in electrical and structural remodeling." tissue_expression_up hsa-mir-21 Spinal Cord Injuries 26323253 "miRâ€?46a, miRâ€?1 and miRâ€?50 expression was upregulated during H2O2 treatment." tissue_expression_up hsa-mir-195 Prostate Neoplasms 26338045 "Collectively,this is the first report unveils that loss of miR-195 expression and thus uncontrolled BCOX1 upregulation might drive PCa metastasis." tissue_expression_up hsa-mir-21 Cardiovascular Diseases [unspecific] 26342092 "MiR-146b-5p, -146a, -21, -150, -155, -299-5p are overexpressed in the presence of inflammation in TABs from patients with GCA." tissue_expression_up hsa-mir-21 "Carcinoma, Breast" 26342497 Chromosome 17 aneusomy and miR-21 expression are positively correlated and can potentially serve as prognostic markers in BC. tissue_expression_up hsa-mir-21 Glioblastoma 26344589 "The results indicate that compound 1j can enhance apoptosis, retard proliferation, and up-regulate PDCD4, a target protein of miR-21. In addition,the compound 1j does not influence the expression of multiple miRNAs and the genes that participate in miRNA universal biosynthesis pathway. These results strongly support the assumption that title compounds can serve as a small molecule inhibitor of miR-21." tissue_expression_up hsa-mir-192 Lung Neoplasms 26351877 "Collectively, our findings suggested that curcumin inhibited cell proliferation and induced apoptosis of human non-small cell lung cancer cells through the upregulation of miR-192-5p and suppression of the PI3K/Akt signaling pathway." tissue_expression_up hsa-mir-134 Ovarian Neoplasms 26363097 "In conclusion, our findings indicate that repression of miR-134 and consequent up-regulation of Pak2 might contribute to paclitaxel resistance." tissue_expression_up hsa-mir-155 Gaucher Disease 26376862 sustained up-regulation of miR-155 tissue_expression_up hsa-mir-31 "Carcinoma, Thyroid, Papillary" 26380656 "miR-21, miR-146b, miR-221, miR-222, miR-31, and miR-3613 were up-regulated" tissue_expression_up hsa-mir-10b Medulloblastoma 26394044 microRNA-10b Is Overexpressed and Critical for Cell Survival and Proliferation in Medulloblastoma. tissue_expression_up hsa-mir-27b "Carcinoma, Cervical" 26397063 "In summary, the present study revealed that miR-27b is upregulated by HPV16 E7 to inhibit PPAR¦Ã expression and promotes proliferation and invasion in cervical carcinoma cells." tissue_expression_up hsa-mir-155 Muscular Dystrophy 26398013 "Up-regulation of immune-related miRNAs in muscle, for example, miR-155 and miR-146, is associated with autoimmunity" tissue_expression_up hsa-mir-155 "Carcinoma, Breast, Triple Negative" 26398931 "These results indicate that miR-155-5p antagonizes bufalin sensitivity in TNBC cells, and that downregulation of DNMT1 and DNMT3a may be responsible for the bufalin-induced upregulation of miR-155-5p." tissue_expression_up hsa-mir-429 Heart Failure 26408546 "17 miRNAs exhibited particularly high increases in expression, including miR-598, miR-429, miR-224, miR-425, and miR-221." tissue_expression_up hsa-mir-21 "Carcinoma, Hepatocellular" 26436398 "We concluded that miR-21 might be complementary to alpha fetal protein in HCC diagnosis, and might serve as an attractive estimator of HCC. We also demonstrated that miR-21 overexpression was associated with HCC TNM stage and with poor survival." tissue_expression_up hsa-mir-106a Glioma 26439036 "Elevated expression of miRNA-106a plays a crucial role in the development and progression of glioma, probably by promoting the proliferation and suppressing the apoptosis of glioma cells through the JNK/MAPK signaling pathway." tissue_expression_up hsa-mir-34a Cardiovascular Diseases [unspecific] 26446137 "overexpression of miR-34a was significantly associated with increased apoptosis, impaired cell vitality and aggravated senescence." tissue_expression_up hsa-mir-15a Leukemia 26456833 miR-223 and miR-15a were upregulated in 11/19 JMML bone marrow mononuclear cells harboring PTPN11 mutations tissue_expression_up hsa-mir-223 Atherosclerosis 26492242 an obvious increase of miR-223 was observed in aortic atherosclerotic lesions. tissue_expression_up hsa-mir-15a "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 26497405 "We detected miR-363 and miR-15a, and their expression levels were significantly increased in the HPV-16-positive patients and in FaDu cells expressing HPV-16 E6-E7." tissue_expression_up hsa-mir-590 Vulvar Squamous Cell Carcinoma 26498065 "In conclusion, we present the miRNA expression profile in VSCC, and our findings suggest that the upregulation of miR-590-5p promotes cellular malignant behaviours via the target gene TGF¦ÂRII." tissue_expression_up hsa-mir-92a Esophageal Neoplasms 26498375 "13 miRNAs were up-regulated including hsa-mir-153-2, hsa-mir-92a-1 and hsa-mir-182; while 27 miRNAs were down-regulated including hsa-mir comprising 29a, hsa-mir-100 and hsa-mir-139 and so on." tissue_expression_up hsa-mir-214 "Scleroderma, Localized" 26498408 The levels of miR-214 in hair shafts of patients with dermatomyositis were significantly higher than those of normal subjects and patients with scleroderma. tissue_expression_up hsa-mir-92b "Squamous Cell Carcinoma, Oral" 26503628 "Taken together, our results indicate that miR-92b upregulation accelerates tumor growth and present a novel mechanism of miRNA-mediated NF-¦ÊB activation in OSCC." tissue_expression_up hsa-mir-146a Osteoarthritis 26505891 miR-146a significantly up-regulated and miR-27b significantly down-regulated at all time points tissue_expression_up hsa-mir-145 Urinary Bladder Cancer 26514209 "Results indicate that miR-145 suppresses syndecan-1 and, by this mechanism, up-regulates stem cell factors and induces cell senescence and differentiation. We propose that miR-145 may confer stem cell-like properties on urothelial carcinoma cells and thus facilitate differentiation into multiple cell types." tissue_expression_up hsa-let-7f Colon Neoplasms 26556872 "highly up-regulated miRNAs, let-7f-5p, miR-455-3p, miR-98, miR-155-5p and the down-regulated miRNAs, miR-1, miR-127-5p, miR-142-5p, miR-202-5p were associated with colon cancer pathways" tissue_expression_up hsa-mir-155 Colon Neoplasms 26556872 "highly up-regulated miRNAs, let-7f-5p, miR-455-3p, miR-98, miR-155-5p and the down-regulated miRNAs, miR-1, miR-127-5p, miR-142-5p, miR-202-5p were associated with colon cancer pathways" tissue_expression_up hsa-mir-20a Lung Neoplasms 26560875 increased expression of miR-20 in lung cancer tissue_expression_up hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 26563758 "Higher expression levels of miR-21, AmiR-27a, and miR-218 detected in this study suggest potential roles of these miRNAs in primary resistance to EGFR-TKI in advanced NSCLC patients with EGFR exon 19 deletion mutations. These findings need to be further confirmed in a study with a larger sample size." tissue_expression_up hsa-mir-21 Acute Kidney Failure 26577279 "A set of microRNAs was differentially expressed after renal damage, among them miR-21, which was up-regulated." tissue_expression_up hsa-mir-183 "Carcinoma, Hepatocellular" 26640336 "miRNA-183 was the most up-regulated, followed by miRNA-373. miRNA-129 and miRNA-188 were both strongly down-regulated and miRNA-378 was down-regulated a small amount." tissue_expression_up hsa-mir-22 Toxic Encephalopathy 26649298 "Our results demonstrated that PFOS exposure decreased miR-16 expression and increased miR-22 expression, which may represent a possible mechanism by which PFOS decreases BDNF protein levels. PFOS may inhibit BDNF-ERK-CREB signalling by increasing miR-22 levels, which may, in part, explain the mechanism of PFOS neurotoxicity." tissue_expression_up hsa-mir-106b Cutaneous Melanoma 26662433 This study showed that miR-106b may contribute to the progression of cutaneous melanoma and its up-regulation may be independently associated with poor prognosis of cutaneous melanoma. This suggests that miR-106b might serve as a promising biological marker for further risk stratification in the management of cutaneous melanoma. tissue_expression_up hsa-mir-210 "Carcinoma, Renal Cell, Clear-Cell" 26670229 miR-21-5p and miR-210-3p resulted the most significantly up-regulated miRNAs in this patient cohort tissue_expression_up hsa-mir-132 Aneurysmal Subarachnoid Hemorrhage 26675167 "Our study demonstrated that as compared to healthy control, miR-132 and miR-324 showed a upregulation in both SAH DCI and Non-DCI groups. However,the differences between the SAH DCI and non-DCI groups were not statistically significant." tissue_expression_up hsa-mir-324 Aneurysmal Subarachnoid Hemorrhage 26675167 "Our study demonstrated that as compared to healthy control, miR-132 and miR-324 showed a upregulation in both SAH DCI and Non-DCI groups. However,the differences between the SAH DCI and non-DCI groups were not statistically significant." tissue_expression_up hsa-mir-15b "Lymphoma, Mantle-Cell" 26676972 Our present findings suggest that the upregulated expression of miR-15b is likely to play an important role in the trans-formation of cMCL to aMCL. tissue_expression_up hsa-mir-130a Chronic Alcohol-Induced Alveolar Macrophage Dysfunction 26677910 "Alcohol increased levels of microRNA-130a/-301a, these findings demonstrate that targeting PPAR¦Ã provides a novel therapeutic approach for mitigating alcohol-induced AM derangements and susceptibility to lung infection" tissue_expression_up hsa-mir-301a Chronic Alcohol-Induced Alveolar Macrophage Dysfunction 26677910 "Alcohol increased levels of microRNA-130a/-301a, these findings demonstrate that targeting PPAR¦Ã provides a novel therapeutic approach for mitigating alcohol-induced AM derangements and susceptibility to lung infection" tissue_expression_up hsa-mir-205 Neoplasms [unspecific] 26681200 "miR-9, mi-R-19a, miR-22 and miR-205 that promote EMT, fibrosis and tumorigenesis were up-regulated." tissue_expression_up hsa-mir-126 "Lymphoma, Large B-Cell, Diffuse" 26683099 "We observed increased expression of proangiomiRs Let-7f, miR-17, miR-18a, miR-19b, miR-126, miR-130a, miR-210, miR-296 and miR-378" tissue_expression_up hsa-mir-130a "Lymphoma, Large B-Cell, Diffuse" 26683099 "We observed increased expression of proangiomiRs Let-7f, miR-17, miR-18a, miR-19b, miR-126, miR-130a, miR-210, miR-296 and miR-378" tissue_expression_up hsa-mir-296 "Lymphoma, Large B-Cell, Diffuse" 26683099 "We observed increased expression of proangiomiRs Let-7f, miR-17, miR-18a, miR-19b, miR-126, miR-130a, miR-210, miR-296 and miR-378" tissue_expression_up hsa-mir-378 "Lymphoma, Large B-Cell, Diffuse" 26683099 "We observed increased expression of proangiomiRs Let-7f, miR-17, miR-18a, miR-19b, miR-126, miR-130a, miR-210, miR-296 and miR-378" tissue_expression_up hsa-mir-125b Melanoma 26684239 "miR-34a, miR-100 and miR-125b showed high expression in both resistant cells and in tumor biopsies" tissue_expression_up hsa-mir-381 Neoplasms [unspecific] 26688820 Further study revealed that I¦ÊB¦Á was a target gene of miR-381. The upregulation of miR-381 under LPS stimulation contributes to respiratory infections mainly by targeting I¦ÊB¦Á. tissue_expression_up hsa-mir-205 Barrett Esophagus 26711784 we observed significantly higher levels of miR-205 in tumor tissue of esophageal squamous cell carcinoma tissue_expression_up hsa-mir-205 Choriocarcinoma 26711784 we observed significantly higher levels of miR-205 in tumor tissue of esophageal squamous cell carcinoma tissue_expression_up hsa-mir-103a Pancreatic Neoplasms 26714641 "We identified suitable reference miRNAs for future miRNA expression experiments using CRC- and PC FFPE tissue samples. Formalin fixation decreased miRNA expression considerably, while the effect of increasing sample age was estimated to be negligible in a clinical setting." tissue_expression_up hsa-mir-9 "Stroke, Ischemic" 26718002 The expression of miR-9 in the peri-infarct cortex was increased in the EA group compared with the MCAO group tissue_expression_up hsa-mir-27a Glaucoma 26720444 miR-27a was significantly upregulated. tissue_expression_up hsa-mir-146a Stroke 26738853 stroke considerably increased miR-146a density in the corpus callosum and subventricular zone (SVZ) of the lateral ventricle of the ischemic hemisphere. tissue_expression_up hsa-mir-222 Thyroid Neoplasms 26745212 miR-221 and miR-222 are consistently upregulated in different types of thyroid carcinomas tissue_expression_up hsa-mir-146a Inflammatory Bowel Diseases 26752469 Expression of miR-146a and -155 was higher in the inflamed mucosa of children with CD and UC than in the intact mucosa. Expression of miR-122 elevated in the macroscopically intact colonic regions of CD compared with controls and patients with UC. tissue_expression_up hsa-mir-622 Ovarian Neoplasms 26774475 Platinum and PARP Inhibitor Resistance Due to Overexpression of MicroRNA-622 in BRCA1-Mutant Ovarian Cancer. tissue_expression_up hsa-mir-200a Colorectal Carcinoma 26790446 "The expression of MMP-2 and -9 was elevated, on the other hand, in cell lines derived from primary tumor cancer cells as well as the expression of miR-21, miR-29a, and miR-200a." tissue_expression_up hsa-mir-21 Colorectal Carcinoma 26790446 "The expression of MMP-2 and -9 was elevated, on the other hand, in cell lines derived from primary tumor cancer cells as well as the expression of miR-21, miR-29a, and miR-200a." tissue_expression_up hsa-mir-29a Colorectal Carcinoma 26790446 "The expression of MMP-2 and -9 was elevated, on the other hand, in cell lines derived from primary tumor cancer cells as well as the expression of miR-21, miR-29a, and miR-200a." tissue_expression_up hsa-mir-21 Choriocarcinoma 26807210 "the expression of miR-200b, miR-200c, miR-451, miR-223 and miR-21 were significantly upregulated in mucinous cystadenocarcinoma" tissue_expression_up hsa-mir-223 Choriocarcinoma 26807210 "the expression of miR-200b, miR-200c, miR-451, miR-223 and miR-21 were significantly upregulated in mucinous cystadenocarcinoma" tissue_expression_up hsa-mir-15a Astrocytoma 26813564 miR-15a and miR-24-1 were found upregulated in EP relapsed and EP deceased cases tissue_expression_up hsa-mir-15a Ependymoma 26813564 miR-15a and miR-24-1 were found upregulated in EP relapsed and EP deceased cases tissue_expression_up hsa-mir-24 Astrocytoma 26813564 miR-15a and miR-24-1 were found upregulated in EP relapsed and EP deceased cases tissue_expression_up hsa-mir-24 Ependymoma 26813564 miR-15a and miR-24-1 were found upregulated in EP relapsed and EP deceased cases tissue_expression_up hsa-mir-375 "Carcinoma, Thyroid, Follicular" 26818914 Only miR-375 was over-expressed in the FNs diagnosed as carcinomas and in the PMs. tissue_expression_up hsa-mir-21 Gastric Neoplasms 26824898 hsa-miR-21-5p was more highly expressed in the recurrence group than in the nonrecurrence group tissue_expression_up hsa-mir-221 "Carcinoma, Lung, Non-Small-Cell" 26831656 The relative expression levels of microRNA-221 in the pathological tissues were remarkably higher than that in the corresponding normal tissues tissue_expression_up hsa-mir-138 "Squamous Cell Carcinoma, Oral" 26841253 Upregulation of miR-138 and miR-183 was observed in 50.0% of the samples tissue_expression_up hsa-mir-183 "Squamous Cell Carcinoma, Oral" 26841253 Upregulation of miR-138 and miR-183 was observed in 50.0% of the samples tissue_expression_up hsa-mir-205 "Squamous Cell Carcinoma, Oral" 26841253 "Upregulation of miR-138, miRNA-145, and miR-205 was associated with advanced tumor stages, vascular invasion, and lymph node metastasis, respectively." tissue_expression_up hsa-mir-4423 Cardiotoxicity 26842497 "early deregulation of miR-187-3p, miR-182-5p, miR-486-3p, miR-486-5p, miR-34a-3p, miR-4423-3p, miR-34c-3p, miR-34c-5p and miR-1303, and also the prolonged up-regulation of miR-182-5p, miR-4423-3p and miR-34c-5p." tissue_expression_up hsa-mir-761 "Carcinoma, Hepatocellular" 26845057 MicroRNA-761 is upregulated in hepatocellular carcinoma and regulates tumorigenesis by targeting Mitofusin-2. tissue_expression_up hsa-mir-21 Colorectal Carcinoma 26845148 "In the context of previous studies demonstrating increased miRNA-21 expression in metastatic primary tumors, our findings raise the question whether miRNA-21 might be involved in the initiation but not in the perpetuation and growth of metastases." tissue_expression_up hsa-mir-155 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 26847279 "The expression of tissue and plasma miR-155 were significantly up-regulated in patients with LSCC. Our work will serve as a basis for further investigation, preferably large-scale validation in clinical trials." tissue_expression_up hsa-mir-155 Neoplasms [unspecific] 26850462 miR-155 is an oncogenic miRNA that is often overexpressed in cancer and is associated with poor prognosis. tissue_expression_up hsa-mir-210 "Squamous Cell Carcinoma, Esophageal" 26851030 "squamous cell carcinoma (9.26-fold, p<0.001) and adenocarcinoma cell lines (4.95-fold, p<0.001) and miR-27a-star was significantly up-regulated in adenocarcinoma cell lines (4.79-fold, p=0.04)." tissue_expression_up hsa-mir-21 Preeclampsia 26859593 "we could observe a significant increase in gene expression of miR-155 (p<0.001), miR-21 (p<0.0001) and miR-122 (p<0.01) in preeclamptic placentas." tissue_expression_up hsa-mir-130a Hepatitis B Virus Infection 26871786 Upregulation of miRNA-130a Represents Good Prognosis in Patients With HBV-Related Acute-on-Chronic Liver Failure: A Prospective Study. tissue_expression_up hsa-mir-132 Inflammatory Bowel Diseases 26878986 significant upregulation of miR-132 and miR-223 was confirmed tissue_expression_up hsa-mir-223 Inflammatory Bowel Diseases 26878986 significant upregulation of miR-132 and miR-223 was confirmed tissue_expression_up hsa-mir-181a "Diabetes Mellitus, Type 1" 26892629 miRNA-181a expression was significantly higher in diabetic children and adolescents tissue_expression_up hsa-mir-155 Breast Neoplasms 26901459 MiRNA-155 was selected for being overexpressed in breast cancer tissue_expression_up hsa-mir-31 Esophageal Neoplasms 26918602 "miR-223, miR-21, and miR-31 as the top-up-regulated species" tissue_expression_up hsa-mir-155 Vitiligo 26941046 "miR-99b, miR-125b, miR-155 and miR-199a-3p were found to be increased and miR-145 was found to be decreased in the skin of patients with vitiligo." tissue_expression_up hsa-mir-103a Helicobacter pylori Infection 26945693 "miRNAs miR-103a-3p, miR-181c-5p, miR-370-3p, miR-375 and miR-223-3p were evaluated in tissue samples" tissue_expression_up hsa-mir-181c Helicobacter pylori Infection 26945693 "miRNAs miR-103a-3p, miR-181c-5p, miR-370-3p, miR-375 and miR-223-3p were evaluated in tissue samples" tissue_expression_up hsa-mir-223 Helicobacter pylori Infection 26945693 "miRNAs miR-103a-3p, miR-181c-5p, miR-370-3p, miR-375 and miR-223-3p were evaluated in tissue samples" tissue_expression_up hsa-mir-370 Helicobacter pylori Infection 26945693 "miRNAs miR-103a-3p, miR-181c-5p, miR-370-3p, miR-375 and miR-223-3p were evaluated in tissue samples" tissue_expression_up hsa-mir-375 Helicobacter pylori Infection 26945693 "miRNAs miR-103a-3p, miR-181c-5p, miR-370-3p, miR-375 and miR-223-3p were evaluated in tissue samples" tissue_expression_up hsa-mir-20a "Lymphoma, Hodgkin" 26951445 miR-20a-5p were found to be increased in cHL tissue_expression_up hsa-mir-150 Lupus Nephritis 26961386 Overexpression of miR-150 is observed in renal biopsies from patients with lupus nephritis tissue_expression_up hsa-mir-182 Hypoxic-Ischemic Encephalopathy 26975828 miRNA-182 was highly expressed in the pineal gland. tissue_expression_up hsa-mir-27a "Carcinoma, Cervical" 26987623 B4GALT3 up-regulation by miR-27a contributes to the oncogenic activity in human cervical cancer cells. tissue_expression_up hsa-mir-21 Periodontitis 26987780 "Seven randomly selected up-regulated (miR-21-5p, 498, 548a-5p) and down-regulated (miR-495-3p, 539-5p, 34c-3p and 7a-2-3p) miRNAs were examined by qRT-PCR, and the results proved the accuracy of the miRNA" tissue_expression_up hsa-mir-10b Glioma 26988656 Expression levels of miR-10b in glioma tissue were significantly higher than in normal brain tissue tissue_expression_up hsa-mir-301a Prostate Neoplasms 26990571 High levels of miR-301a (above the median) were associated with an increased risk of biochemical recurrence tissue_expression_up hsa-mir-210 Melanoma 27009863 Hypoxia-induced gene signatures and overexpression of the hypoxia-regulated miRNA hsa-miR-210 characterized CDXs. tissue_expression_up hsa-mir-595 "Carcinoma, Thyroid, Papillary" 27022736 "Interestingly, in PTC cell lines and PTC tissues, expression of IL-22 and miR-595 was upregulated and Sox17 downregulated compared with normal thyroid" tissue_expression_up hsa-mir-21 Prostate Neoplasms 27040772 the expression level of miR-21 was significantly increased in PCa tissues tissue_expression_up hsa-mir-9 Osteosarcoma 27051003 miR-9 was significantly upregulated in OS tissues and cell lines compared to the corresponding non-cancerous bone tissues tissue_expression_up hsa-mir-200a Melanoma 27054085 "Among the up-regulated miRNAs, miR-21, miR-200a and miR-141, are well known to be involved in carcinogenesis." tissue_expression_up hsa-mir-142 "Squamous Cell Carcinoma, Oral" 27056547 "let-7a, let-7d, let-7f and miR-16 were downregulated while miR-29b, miR-142-3p, miR-144, miR-203, and miR-223 were upregulated in OSCC" tissue_expression_up hsa-mir-144 "Squamous Cell Carcinoma, Oral" 27056547 "let-7a, let-7d, let-7f and miR-16 were downregulated while miR-29b, miR-142-3p, miR-144, miR-203, and miR-223 were upregulated in OSCC" tissue_expression_up hsa-mir-203 "Squamous Cell Carcinoma, Oral" 27056547 "let-7a, let-7d, let-7f and miR-16 were downregulated while miR-29b, miR-142-3p, miR-144, miR-203, and miR-223 were upregulated in OSCC" tissue_expression_up hsa-mir-223 "Squamous Cell Carcinoma, Oral" 27056547 "let-7a, let-7d, let-7f and miR-16 were downregulated while miR-29b, miR-142-3p, miR-144, miR-203, and miR-223 were upregulated in OSCC" tissue_expression_up hsa-mir-29b "Squamous Cell Carcinoma, Oral" 27056547 "let-7a, let-7d, let-7f and miR-16 were downregulated while miR-29b, miR-142-3p, miR-144, miR-203, and miR-223 were upregulated in OSCC" tissue_expression_up hsa-mir-149 "Fatty Liver, Non-Alcoholic" 27061435 miR-149 was increased in HepG2 cells treated with long-chain fatty acid (FFA) tissue_expression_up hsa-mir-128 Glioblastoma 27063952 "The three most over-expressed miRs in the non-differentiated GSCs compared to xenografts were miR-126, -137 and -128." tissue_expression_up hsa-mir-181a Heart Failure 27072074 "In coronary sinus samples, the microRNAs miR-16-5p, miR-27a-3p, miR-27b-3p, miR-29b-3p, miR-29c-3p, miR-30e-5p, miR-92a-3p, miR-125b-5p, miR-140-5p, miR-195-5p, miR-424-5p, and miR-451a were significantly down-regulated, and let-7a-5p, let-7c-5p, let-7e-5p, miR-23b-3p, miR-107, miR-155-5p, miR-181a-5p, miR-181b-5p and miR-320a were up-regulated in heart failure." tissue_expression_up hsa-mir-21 "Carcinoma, Lung, Non-Small-Cell" 27072269 "miR-15a/16, miR-34a, miR-126 and miR-128 were down-regulated significantly. (>2-fold change), while miR-21 and miR.210 were up-regulated in A549." tissue_expression_up hsa-mir-210 "Carcinoma, Lung, Non-Small-Cell" 27072269 "miR-15a/16, miR-34a, miR-126 and miR-128 were down-regulated significantly. (>2-fold change), while miR-21 and miR.210 were up-regulated in A549." tissue_expression_up hsa-mir-146a Rheumatoid Arthritis 27079198 "miR-146a, miR-155, and miR-223 were significantly elevated in RA compared to OA synovial tissues" tissue_expression_up hsa-mir-155 Rheumatoid Arthritis 27079198 "miR-146a, miR-155, and miR-223 were significantly elevated in RA compared to OA synovial tissues" tissue_expression_up hsa-mir-223 Rheumatoid Arthritis 27079198 "miR-146a, miR-155, and miR-223 were significantly elevated in RA compared to OA synovial tissues" tissue_expression_up hsa-mir-21 Breast Neoplasms 27082076 included upregulation of miR-21-5p and the miR-200 family and downregulation of let-7 family members in DCIS samples. tissue_expression_up hsa-mir-23a Coronary Artery Disease 27085964 MiR-23a was enriched in not only diseased endothelial progenitor cells (EPCs) but also in the plasma of patients with coronary artery disease (CAD). tissue_expression_up hsa-mir-155 "Leukemia, Lymphocytic, Chronic, B-Cell" 27111859 miR-143 was downregulated and miR-155 was overexpressed in 13q-H. tissue_expression_up hsa-mir-146a Hepatitis C Virus Infection 27147737 miR-146a-5p level was consistently increased in HCV-infected hepatocyte-like cells tissue_expression_up hsa-mir-155 Behcet Disease 27156371 The expression of miR-155 and IL-17 was significantly increased in CD4+ T cells of patients with active BD. tissue_expression_up hsa-let-7b Prostate Neoplasms 27157642 up-regulation of let-7b is characteristic of prostatic TAMs tissue_expression_up hsa-mir-125b Hepatitis C Virus Infection 27158204 "In response to HCV core protein stimulation, cytokine production was up-regulated and miR-125b expression was down-regulated in THP-1 cells." tissue_expression_up hsa-mir-155 Renal Fibrosis 27158339 MiR-155 levels were higher in UUO mouse kidneys tissue_expression_up hsa-mir-199a Pulmonary Hypertension 27162619 All 4 miRNAs were upregulated in the lung and right ventricle tissue_expression_up hsa-mir-425 Cervical Neoplasms 27166306 miR-425-5p is up-regulated in cervical cancer and serum miR-425-5p may serve as a potential prognostic biomarker for cervical cancer. tissue_expression_up hsa-mir-141 Biliary Tract Neoplasms 27172928 Overexpression of miRNA 141 is an indicator of a poor prognosis in patients with biliary tract cancer tissue_expression_up hsa-mir-4532 Hypertension 27176897 "4 were upregulated (miRâ€?18a, miRâ€?27, miRâ€?18e and miRâ€?532) and 2 downregulated (miRâ€?8 and miRâ€?35b) in SPE placentas compared with controls." tissue_expression_up hsa-mir-518a Hypertension 27176897 "4 were upregulated (miRâ€?18a, miRâ€?27, miRâ€?18e and miRâ€?532) and 2 downregulated (miRâ€?8 and miRâ€?35b) in SPE placentas compared with controls." tissue_expression_up hsa-mir-518e Hypertension 27176897 "4 were upregulated (miRâ€?18a, miRâ€?27, miRâ€?18e and miRâ€?532) and 2 downregulated (miRâ€?8 and miRâ€?35b) in SPE placentas compared with controls." tissue_expression_up hsa-mir-527 Hypertension 27176897 "4 were upregulated (miRâ€?18a, miRâ€?27, miRâ€?18e and miRâ€?532) and 2 downregulated (miRâ€?8 and miRâ€?35b) in SPE placentas compared with controls." tissue_expression_up hsa-mir-21 Gastric Neoplasms 27179559 miR-21 is overexpressed in tumour tissue tissue_expression_up hsa-mir-21 Salivary Gland Neoplasms 27184509 "tissue samples were studied miR-21, miR-31, miR-199a-5p, miR-146b, miR-345 were up-regulated" tissue_expression_up hsa-mir-93 Glioma 27185265 the upregulated miR-93 level was significantly associated with the advanced malignancy. tissue_expression_up hsa-mir-10b "Carcinoma, Nasopharyngeal" 27186392 we show that microRNA-10b (miR-10b) is up-regulated in HNE1/DDP cells tissue_expression_up hsa-mir-182 Alcoholic Hepatitis 27196584 miR-182 was the most highly expressed miRNA in AH tissue_expression_up hsa-mir-301b Pancreatic Neoplasms 27197190 PDAC tumors expressing high levels of MIF displayed elevated levels of miR-301b and reduced levels of NR3C2. tissue_expression_up hsa-mir-183 Glioma 27215622 "In conclusion, our study indicated that miR-183 was upregulated in glioma, and that it may be used as a potential biomarker of poor prognosis in patients with glioma." tissue_expression_up hsa-mir-206 Soft Tissue Sarcoma 27223121 "At least threefold overexpression of one of miR-206,-381, and 671-5p was detected in all MPNSTs, EMCSs, SSs and 7 MCs." tissue_expression_up hsa-mir-381 Soft Tissue Sarcoma 27223121 "At least threefold overexpression of one of miR-206,-381, and 671-5p was detected in all MPNSTs, EMCSs, SSs and 7 MCs." tissue_expression_up hsa-mir-671 Soft Tissue Sarcoma 27223121 "At least threefold overexpression of one of miR-206,-381, and 671-5p was detected in all MPNSTs, EMCSs, SSs and 7 MCs." tissue_expression_up hsa-mir-29a Acute Pancreatitis 27239114 The expression of miR-29a was much higher in the AEP group compared with the control group tissue_expression_up hsa-mir-126 Asthma 27247924 "Elevated levels of miRNA-126, IL-13 mRNA and pathological changes were observed in the sensitized group compared to the control group" tissue_expression_up hsa-mir-1287 Colorectal Carcinoma 27251300 MiR-1287 was significantly upregulated in the group of CRC samples compared with matched noncancerous tissue samples. tissue_expression_up hsa-mir-128a Preeclampsia 27261578 miR-128a is an up-regulated miRNA in patient with PE. tissue_expression_up hsa-mir-181a Colorectal Carcinoma 27264420 IL-1β induced the expression of miR-181a. tissue_expression_up hsa-mir-196 "Adenocarcinoma, Pancreatic Ductal" 27267055 The expressions of all microRNAs were 1.4-3.7 times higher (significantly) in the PAC group compared to non-cancer patients. tissue_expression_up hsa-mir-200 "Adenocarcinoma, Pancreatic Ductal" 27267055 The expressions of all microRNAs were 1.4-3.7 times higher (significantly) in the PAC group compared to non-cancer patients. tissue_expression_up hsa-mir-21 Cervical Neoplasms 27278606 the expression of miR-21 was upregulated and the expression of miR-143 was downregulated by the HPV16 E7 oncoprotein in vivo tissue_expression_up hsa-mir-199a Obesity 27279151 miRâ€?99aâ€?p may represent a factor in the modulation of obesity‑associated IR tissue_expression_up hsa-mir-9 Neoplasms [unspecific] 27284255 higher expression level of miR-9 significantly predicted worse OS in various carcinomas tissue_expression_up hsa-mir-126 Atherosclerosis 27288564 "Aroclor 1260 increased miR-21, miR-31, miR-126, miR-221 and miR-222 expression levels." tissue_expression_up hsa-mir-21 Atherosclerosis 27288564 "Aroclor 1260 increased miR-21, miR-31, miR-126, miR-221 and miR-222 expression levels." tissue_expression_up hsa-mir-221 Atherosclerosis 27288564 "Aroclor 1260 increased miR-21, miR-31, miR-126, miR-221 and miR-222 expression levels." tissue_expression_up hsa-mir-222 Atherosclerosis 27288564 "Aroclor 1260 increased miR-21, miR-31, miR-126, miR-221 and miR-222 expression levels." tissue_expression_up hsa-mir-31 Atherosclerosis 27288564 "Aroclor 1260 increased miR-21, miR-31, miR-126, miR-221 and miR-222 expression levels." tissue_expression_up hsa-mir-181b "Carcinoma, Lung, Non-Small-Cell" 27291819 miR-181b-5p was up-regulated in squamous cell carcinoma tissue_expression_up hsa-mir-133a "Cardiomyopathy, Dilated" 27292200 "Endomyocardial expression of miR-155 and miR-133a, as quantified by reverse transcription-PCR (RT-PCR), was up-regulated in patients with iCMP as compared with patients with DCM." tissue_expression_up hsa-mir-182 Ovarian Neoplasms 27295517 miR-182 expression is significantly increased in EOC tissue_expression_up hsa-mir-106b "Carcinoma, Hepatocellular" 27298561 The value of miR-106b expression in HBV-associated HCC patients was significantly higher tissue_expression_up hsa-mir-200c Interstitial Lung Disease 27309544 "The miR-200c level in the SSc group was significantly higher than in the DM/PM, pSS, and RA groups" tissue_expression_up hsa-mir-155 Multiple Sclerosis 27310932 up-regulation of miR-155 (p value = 0.009) and miR-132 (p value = 0.04) in MS patients tissue_expression_up hsa-mir-208a Myocardial Infarction 27314868 over-expression of miR-208a in myocardial infarction tissue tissue_expression_up hsa-mir-486 Kideny Transplant Rejection 27323802 iR-486-5p and its target PTEN/foxO3 mRNA were significantly overexpressed (pâ€?â€?.01) and underexpressed (pâ€?â€?.01) tissue_expression_up hsa-mir-301a Prostate Neoplasms 27327120 MiR-301a and miR-301b are 2 hypoxia responsive miRNAs that are significantly upregulated in hypoxia in prostate cancer cells. tissue_expression_up hsa-mir-301b Prostate Neoplasms 27327120 MiR-301a and miR-301b are 2 hypoxia responsive miRNAs that are significantly upregulated in hypoxia in prostate cancer cells. tissue_expression_up hsa-mir-9 Cervical Neoplasms 27345415 MiR-9 up-regulated in cervical cancer tissue_expression_up hsa-mir-126 "Shock, Hemorrhagic" 27345902 miR-29a and miR-126 were upregulated tissue_expression_up hsa-mir-29a "Shock, Hemorrhagic" 27345902 miR-29a and miR-126 were upregulated tissue_expression_up hsa-mir-29b Colorectal Carcinoma 27346400 The expression level of miR-29b is reduced in colorectal cancer tissues compared with that in the adjacent colorectal tissues. tissue_expression_up hsa-mir-146b "Carcinoma, Thyroid" 27347103 "the expression levels of miR146b, miR221 and miR222 were significantly higher" tissue_expression_up hsa-mir-221 "Carcinoma, Thyroid" 27347103 "the expression levels of miR146b, miR221 and miR222 were significantly higher" tissue_expression_up hsa-mir-100 Bladder Neoplasms 27350368 "six up-regulated candidate miRNAs (miR-182-5p, miR-935, miR-518e-3p, miR-573, miR-100-3p, and miR-3171)" tissue_expression_up hsa-mir-182 Bladder Neoplasms 27350368 "six up-regulated candidate miRNAs (miR-182-5p, miR-935, miR-518e-3p, miR-573, miR-100-3p, and miR-3171)" tissue_expression_up hsa-mir-3171 Bladder Neoplasms 27350368 "six up-regulated candidate miRNAs (miR-182-5p, miR-935, miR-518e-3p, miR-573, miR-100-3p, and miR-3171)" tissue_expression_up hsa-mir-518e Bladder Neoplasms 27350368 "six up-regulated candidate miRNAs (miR-182-5p, miR-935, miR-518e-3p, miR-573, miR-100-3p, and miR-3171)" tissue_expression_up hsa-mir-573 Bladder Neoplasms 27350368 "six up-regulated candidate miRNAs (miR-182-5p, miR-935, miR-518e-3p, miR-573, miR-100-3p, and miR-3171)" tissue_expression_up hsa-mir-935 Bladder Neoplasms 27350368 "six up-regulated candidate miRNAs (miR-182-5p, miR-935, miR-518e-3p, miR-573, miR-100-3p, and miR-3171)" tissue_expression_up hsa-mir-192 Hepatitis C Virus Infection 27350618 miR-192 expression was induced by HCV infection tissue_expression_up hsa-mir-21 Proliferative Vitreoretinal Disease 27351379 miR-21 expression positively correlates with disease progression tissue_expression_up hsa-mir-372 "Carcinoma, Urothelial" 27351382 "high primary tumour levels of E2F1, miR-21 and miR-372 are associated with poor PFS independent of clinical prognostic factors." tissue_expression_up hsa-mir-222 Thyroid Neoplasms 27353001 miR-25 and miR-222 expression was upregulated in 8505C tissue_expression_up hsa-mir-25 Thyroid Neoplasms 27353001 miR-25 and miR-222 expression was upregulated in 8505C tissue_expression_up hsa-mir-34 Idiopathic Pulmonary Fibrosis 27362652 "miR-34a, miR-34b, and miR-34c, but not miR-20a, miR-29c, or miR-let-7f were significantly higher in type II AECs from IPF patients." tissue_expression_up hsa-mir-506 "Adenocarcinoma, Pancreatic Ductal" 27371108 miR-506 expression was higher in PDAC tissue_expression_up hsa-mir-143 Barrett Esophagus 27374102 "miR-143, miR-145, miR-194 and miR-215 levels were significantly higher" tissue_expression_up hsa-mir-143 Choriocarcinoma 27374102 "miR-143, miR-145, miR-194 and miR-215 levels were significantly higher" tissue_expression_up hsa-mir-194 Barrett Esophagus 27374102 "miR-143, miR-145, miR-194 and miR-215 levels were significantly higher" tissue_expression_up hsa-mir-215 Barrett Esophagus 27374102 "miR-143, miR-145, miR-194 and miR-215 levels were significantly higher" tissue_expression_up hsa-mir-210 Cerebral Ischemia 27386874 "miR-210 expression in the hippocampus of the I/R group at 6, 24 and 96 h after reperfusion was significantly increased at each time point, while its expression in the group treated with HRS was significantly decreased." tissue_expression_up hsa-mir-34 Liver Fibrosis 27387128 Further studies showed that the miR-34a/SIRT1/p53 signaling pathway was activated in hepatocytes but not in HSCs. tissue_expression_up hsa-mir-34a Liver Fibrosis 27387128 "In the present study, using a CCl4-induced rat liver fibrosis model, we found that the miR-34a/SIRT1/p53 signaling pathway was activated and could be inhibited by SIRT1 activator SRT1720." tissue_expression_up hsa-mir-141 Sarcoma [unspecific] 27402864 combined expression of miR-200s and GRHL2 further upregulates epithelial genes to induce MET. tissue_expression_up hsa-mir-200a Sarcoma [unspecific] 27402864 combined expression of miR-200s and GRHL2 further upregulates epithelial genes to induce MET. tissue_expression_up hsa-mir-200b Sarcoma [unspecific] 27402864 combined expression of miR-200s and GRHL2 further upregulates epithelial genes to induce MET. tissue_expression_up hsa-mir-200c Sarcoma [unspecific] 27402864 combined expression of miR-200s and GRHL2 further upregulates epithelial genes to induce MET. tissue_expression_up hsa-mir-429 Sarcoma [unspecific] 27402864 combined expression of miR-200s and GRHL2 further upregulates epithelial genes to induce MET. tissue_expression_up hsa-let-7a "Carcinoma, Breast, Triple Negative" 27404381 "Interestingly, despite being a known tumor suppressor, Let-7a showed a significant overexpression in TNBCs." tissue_expression_up hsa-mir-21 "Carcinoma, Breast, Triple Negative" 27404381 "While miR-21, miR-221 and miR-210 showed significant over-expression, miR-195 and miR-145 were downregulated and well correlated with various clinicopathological and demographic risk factors, tumor grade, clinical stage and hormone receptor status." tissue_expression_up hsa-mir-210 "Carcinoma, Breast, Triple Negative" 27404381 "While miR-21, miR-221 and miR-210 showed significant over-expression, miR-195 and miR-145 were downregulated and well correlated with various clinicopathological and demographic risk factors, tumor grade, clinical stage and hormone receptor status." tissue_expression_up hsa-mir-221 "Carcinoma, Breast, Triple Negative" 27404381 "While miR-21, miR-221 and miR-210 showed significant over-expression, miR-195 and miR-145 were downregulated and well correlated with various clinicopathological and demographic risk factors, tumor grade, clinical stage and hormone receptor status." tissue_expression_up hsa-mir-483 Atrial Fibrillation 27422887 Sixteen microRNAs were differentially expressed in the atrial myocardium of POAF patients when compared with those maintaining sinus rhythm. miR-208a was the most underexpressed [fold change (FC) = 2.458] and miR-483-5p the most overexpressed (FC = 1.804). tissue_expression_up hsa-mir-221 "Carcinoma, Renal Cell, Clear-Cell" 27427222 miRNA-21 and miRNA-221 expressions were significantly up-regulated in tumor specimens compared to normal tissue (P<0.05). tissue_expression_up hsa-mir-375 "Squamous Cell Carcinoma, Laryngeal or Hypopharyngeal" 27446362 "The results of the present study suggested that miR-148a and miR-375 were significantly upregulated in LSCC tissues, and increased expression of miR-375 was associated with a more aggressive phenotype of LSCC." tissue_expression_up hsa-mir-146a Crohn Disease 27468194 The elevated expression of miR-146a and -155 in the inflamed duodenal mucosa of CD patients suggests the role of these miRs in the pathomechanism of inflammatory bowel disease. tissue_expression_up hsa-mir-155 Crohn Disease 27468194 The elevated expression of miR-146a and -155 in the inflamed duodenal mucosa of CD patients suggests the role of these miRs in the pathomechanism of inflammatory bowel disease. tissue_expression_up hsa-mir-155 Melanoma 27469124 "A comparison of Spitzoid melanomas to benign nevi revealed overexpression of miR-21, miR-150, and miR-155 in the malignant primaries (p < 0.05)." tissue_expression_up hsa-mir-155 Lymphoma 27473081 "T-MF showed higher miR17 and miR-18a expression compared to F-MF and TR-MF (p â‰?0.0387) while miR19b, miR92a, and miR-155 showed increased levels in F-MF and TR-MF with respect to T-MF (p â‰?0.0360)." tissue_expression_up hsa-mir-17 Lymphoma 27473081 "Furthermore, MF patients showed higher miRNA expression compared to controls (p â‰?0.0223). T-MF showed higher miR17 and miR-18a expression compared to F-MF and TR-MF (p â‰?0.0387) while miR19b, miR92a, and miR-155 showed increased levels in F-MF and TR-MF with respect to T-MF (p â‰?0.0360)." tissue_expression_up hsa-mir-18a Lymphoma 27473081 "Furthermore, MF patients showed higher miRNA expression compared to controls (p â‰?0.0223). T-MF showed higher miR17 and miR-18a expression compared to F-MF and TR-MF (p â‰?0.0387) while miR19b, miR92a, and miR-155 showed increased levels in F-MF and TR-MF with respect to T-MF (p â‰?0.0360)." tissue_expression_up hsa-mir-19b Lymphoma 27473081 "Furthermore, MF patients showed higher miRNA expression compared to controls (p â‰?0.0223). T-MF showed higher miR17 and miR-18a expression compared to F-MF and TR-MF (p â‰?0.0387) while miR19b, miR92a, and miR-155 showed increased levels in F-MF and TR-MF with respect to T-MF (p â‰?0.0360)." tissue_expression_up hsa-mir-92a Lymphoma 27473081 "Furthermore, MF patients showed higher miRNA expression compared to controls (p â‰?0.0223). T-MF showed higher miR17 and miR-18a expression compared to F-MF and TR-MF (p â‰?0.0387) while miR19b, miR92a, and miR-155 showed increased levels in F-MF and TR-MF with respect to T-MF (p â‰?0.0360)." tissue_expression_up hsa-mir-146b Otitis Media 27497395 Middle ear miR-146a and miR-146b expression was elevated in otitis media patients relative to control subjects and correlated with middle ear epithelial thickness. tissue_expression_up hsa-mir-221 "Adenocarcinoma, Esophageal" 27501171 MiR-221 was overexpressed in 5-FU resistant EC cell lines as well as in human EAC tissue. tissue_expression_up hsa-mir-181b "Squamous Cell Carcinoma, Oral" 27509922 he expression levels of miRâ€?81b and Bclâ€? in OVC were significantly higher compared with normal mucosal tissue (NM); tissue_expression_up hsa-mir-34b Seizures 27514646 "We discovered that miR-34b-5p, a member of the miR-34 family, increased significantly in flurothyl-treated rat hippocampus tissue." tissue_expression_up hsa-mir-210 Male Infertility 27535712 " Compared with obstructive azoospermia (OA) as normal control, our results suggest that miR-210 was significantly up-regulated in testis of patients with NOA (P<0.05)" tissue_expression_up hsa-let-7b Chronic Inflammation 27539004 "PM2.5 exposure increased miR-3560 and let-7b-5p in the hippocampus, two proteins that regulate genes Oxct1 and Lin28b that control ketogenesis and glycosylation, and neural cell differentiation, respectively" tissue_expression_up hsa-mir-3560 Chronic Inflammation 27539004 "PM2.5 exposure increased miR-3560 and let-7b-5p in the hippocampus, two proteins that regulate genes Oxct1 and Lin28b that control ketogenesis and glycosylation, and neural cell differentiation, respectively" tissue_expression_up hsa-mir-3588 Chronic Inflammation 27539004 "Expression levels of cortical miR-6315, miR-3588, and miR-466b-5p were upregulated" tissue_expression_up hsa-mir-466b Chronic Inflammation 27539004 "Expression levels of cortical miR-6315, miR-3588, and miR-466b-5p were upregulated" tissue_expression_up hsa-mir-6315 Chronic Inflammation 27539004 "Expression levels of cortical miR-6315, miR-3588, and miR-466b-5p were upregulated" tissue_expression_up hsa-mir-34a "Stroke, Ischemic" 27545688 Increased Expression of mir-34a-5p and Clinical Association in Acute Ischemic Stroke Patients and in a Rat Model. tissue_expression_up hsa-mir-16 "Carcinoma, Gastric" 27605261 High expression of miR-16 and miR-451 predicating better prognosis in patients with gastric cancer. tissue_expression_up hsa-mir-451 "Carcinoma, Gastric" 27605261 High expression of miR-16 and miR-451 predicating better prognosis in patients with gastric cancer. tissue_expression_up hsa-mir-126 "Carcinoma, Ovarian, Clear Cell" 27612152 MicroRNA Gene Expression Signature Driven by miR-9 Overexpression in Ovarian Clear Cell Carcinoma. tissue_expression_up hsa-mir-9 "Carcinoma, Ovarian, Clear Cell" 27612152 MicroRNA Gene Expression Signature Driven by miR-9 Overexpression in Ovarian Clear Cell Carcinoma. tissue_expression_up hsa-mir-107 "Adenocarcinoma, Colon" 27658891 "the top most upregulated and downregulated miRNAs in HPNM included miR-145, -143, -107, -194, and -26a (upregulated), and miR-663, -1268, -320b, -1275, and -322b (downregulated)" tissue_expression_up hsa-mir-143 "Adenocarcinoma, Colon" 27658891 "the top most upregulated and downregulated miRNAs in HPNM included miR-145, -143, -107, -194, and -26a (upregulated), and miR-663, -1268, -320b, -1275, and -321b (downregulated)" tissue_expression_up hsa-mir-145 "Adenocarcinoma, Colon" 27658891 "the top most upregulated and downregulated miRNAs in HPNM included miR-145, -143, -107, -194, and -26a (upregulated), and miR-663, -1268, -320b, -1275, and -320b (downregulated)" tissue_expression_up hsa-mir-194 "Adenocarcinoma, Colon" 27658891 "the top most upregulated and downregulated miRNAs in HPNM included miR-145, -143, -107, -194, and -26a (upregulated), and miR-663, -1268, -320b, -1275, and -323b (downregulated)" tissue_expression_up hsa-mir-26a "Adenocarcinoma, Colon" 27658891 "the top most upregulated and downregulated miRNAs in HPNM included miR-145, -143, -107, -194, and -26a (upregulated), and miR-663, -1268, -320b, -1275, and -324b (downregulated)" tissue_expression_up hsa-mir-98 Osteoarthritis 27676099 Upregulation of miR-98 Inhibits Apoptosis in Cartilage Cells in Osteoarthritis. tissue_expression_up hsa-mir-155 Psoriasis 27706699 Increased miR-155-5p expression in dermal mesenchymal stem cells of psoriatic patients: comparing the microRNA expression profile by microarray. tissue_expression_up hsa-mir-203 Psoriasis 27729619 upregulation of miR-31/miR-203 and downregulation of hsa-miR-99a/miR-125b work together in concert to facilitate the development of psoriasis pathogenesis tissue_expression_up hsa-mir-31 Psoriasis 27729619 upregulation of miR-31/miR-203 and downregulation of hsa-miR-99a/miR-125b work together in concert to facilitate the development of psoriasis pathogenesis tissue_expression_up hsa-mir-140 "Carcinoma, Breast" 27746365 "MiR-222, miR-29a, miR-34a, miR-423, miR-140, miR-3178, miR-574, miR-6780b and miR-744 exhibited significantly higher expression levels in surgically-resected specimens compared with pre-neoadjuvant chemotherapy biopsies" tissue_expression_up hsa-mir-222 "Carcinoma, Breast" 27746365 "MiR-222, miR-29a, miR-34a, miR-423, miR-140, miR-3178, miR-574, miR-6780b and miR-744 exhibited significantly higher expression levels in surgically-resected specimens compared with pre-neoadjuvant chemotherapy biopsies" tissue_expression_up hsa-mir-29a "Carcinoma, Breast" 27746365 "MiR-222, miR-29a, miR-34a, miR-423, miR-140, miR-3178, miR-574, miR-6780b and miR-744 exhibited significantly higher expression levels in surgically-resected specimens compared with pre-neoadjuvant chemotherapy biopsies" tissue_expression_up hsa-mir-3178 "Carcinoma, Breast" 27746365 "MiR-222, miR-29a, miR-34a, miR-423, miR-140, miR-3178, miR-574, miR-6780b and miR-744 exhibited significantly higher expression levels in surgically-resected specimens compared with pre-neoadjuvant chemotherapy biopsies" tissue_expression_up hsa-mir-34a "Carcinoma, Breast" 27746365 "MiR-222, miR-29a, miR-34a, miR-423, miR-140, miR-3178, miR-574, miR-6780b and miR-744 exhibited significantly higher expression levels in surgically-resected specimens compared with pre-neoadjuvant chemotherapy biopsies" tissue_expression_up hsa-mir-423 "Carcinoma, Breast" 27746365 "MiR-222, miR-29a, miR-34a, miR-423, miR-140, miR-3178, miR-574, miR-6780b and miR-744 exhibited significantly higher expression levels in surgically-resected specimens compared with pre-neoadjuvant chemotherapy biopsies" tissue_expression_up hsa-mir-574 "Carcinoma, Breast" 27746365 "MiR-222, miR-29a, miR-34a, miR-423, miR-140, miR-3178, miR-574, miR-6780b and miR-744 exhibited significantly higher expression levels in surgically-resected specimens compared with pre-neoadjuvant chemotherapy biopsies" tissue_expression_up hsa-mir-6780b "Carcinoma, Breast" 27746365 "MiR-222, miR-29a, miR-34a, miR-423, miR-140, miR-3178, miR-574, miR-6780b and miR-744 exhibited significantly higher expression levels in surgically-resected specimens compared with pre-neoadjuvant chemotherapy biopsies" tissue_expression_up hsa-mir-744 "Carcinoma, Breast" 27746365 "MiR-222, miR-29a, miR-34a, miR-423, miR-140, miR-3178, miR-574, miR-6780b and miR-744 exhibited significantly higher expression levels in surgically-resected specimens compared with pre-neoadjuvant chemotherapy biopsies" tissue_expression_up hsa-mir-222 "Carcinoma, Breast" 27746366 MiR-222 promotes drug-resistance of breast cancer cells to adriamycin via modulation of PTEN/Akt/FOXO1 pathway. tissue_expression_up hsa-mir-543 "Carcinoma, Lung, Non-Small-Cell" 27769862 miR-543 is up-regulated in gefitinib-resistant non-small cell lung cancer and promotes cell proliferation and invasion via phosphatase and tensin homolog. tissue_expression_up hsa-mir-223 Obesity 27812198 Visceral Adipose MicroRNA 223 Is Upregulated in Human and Murine Obesity and Modulates the Inflammatory Phenotype of Macrophages. tissue_expression_up hsa-mir-124 "Squamous Cell Carcinoma, Skin or Unspecific" 27818465 The expression of miR-124 increases in aged skin to cause cell senescence and it decreases in squamous cell carcinoma. tissue_expression_up hsa-mir-16 Rheumatoid Arthritis 27875659 Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis. tissue_expression_up hsa-mir-16 "Adenocarcinoma, Colon" 27930363 Upregulated miR-16 expression is an independent indicator of relapse and poor overall survival of colorectal adenocarcinoma patients. tissue_expression_up hsa-mir-24 "Adenocarcinoma, Colon" 27939727 Elevated expression of miR-24-3p is a potentially adverse prognostic factor in colorectal adenocarcinoma. tissue_expression_up hsa-mir-222 "Carcinoma, Gastric" 27994199 Upregulation of miR-222 in both Helicobacter pylori- infected and noninfected gastric cancer patients. tissue_expression_up hsa-mir-23a Muscle Atrophy 28000445 Delphinidin Prevents Muscle Atrophy and Upregulates miR-23a Expression. tissue_expression_up hsa-mir-15a Glioma 28060761 "Sensitivity and specificity analysis indicated miR-15a, miR-16, miR-21, miR-23a, and miR-9 were up-regulated, while miR-124 was down-regulated in glioma" tissue_expression_up hsa-mir-16 Glioma 28060761 "Sensitivity and specificity analysis indicated miR-15a, miR-16, miR-21, miR-23a, and miR-9 were up-regulated, while miR-124 was down-regulated in glioma" tissue_expression_up hsa-mir-21 Glioma 28060761 "Sensitivity and specificity analysis indicated miR-15a, miR-16, miR-21, miR-23a, and miR-9 were up-regulated, while miR-124 was down-regulated in glioma" tissue_expression_up hsa-mir-23a Glioma 28060761 "Sensitivity and specificity analysis indicated miR-15a, miR-16, miR-21, miR-23a, and miR-9 were up-regulated, while miR-124 was down-regulated in glioma" tissue_expression_up hsa-mir-9 Glioma 28060761 "Sensitivity and specificity analysis indicated miR-15a, miR-16, miR-21, miR-23a, and miR-9 were up-regulated, while miR-124 was down-regulated in glioma" tissue_expression_up hsa-mir-21 "Carcinoma, Skin" 28069514 "Increased microRNA 21 expression contributes to arsenic induced skin lesions, skin cancers and respiratory distress in chronically exposed individuals." tissue_expression_up hsa-mir-125b Acute Peritonitis 28074870 MicroRNA-155 is upregulated in ascites in patients with spontaneous bacterial peritonitis. tissue_expression_up hsa-mir-143 "Carcinoma, Nasopharyngeal" 28105209 Upregulated microRNA-143 inhibits cell proliferation in human nasopharyngeal carcinoma. tissue_expression_up hsa-mir-21 "Carcinoma, Renal Cell" 28184919 Upregulation of miR-21 expression is a valuable predicator of advanced clinicopathological features and poor prognosis in patients with renal cell carcinoma through the p53/p21?cyclin?E2?Bax/caspase-3 signaling pathway. tissue_expression_up hsa-mir-605 "Carcinoma, Renal Cell" 28222071 miR-605 is elevated at baseline in the Responders and is downregulated with treatment in Responders as compared with Progressors tissue_expression_up hsa-mir-193a Nephrotic Syndrome 28299339 The miR-193a expression levels only slightly increased in NS patients tissue_expression_up hsa-let-7b Endocrine Gland Neoplasms 28322989 "Several miRNAs show lowered expression in endocrine cancers (i.e. miR-200s, miR-126, miR-7, miR-29a, miR-30a, miR-137, miR-206, miR-101, miR-613, miR-539, miR-205, miR-9, miR-195), while others are commonly overexpressed (i.e. miR-21, miR-183, miR-31, miR-let7b, miR-584, miR-146b, miR-221, miR-222, miR-25, miR-595)" tissue_expression_up hsa-mir-146b Endocrine Gland Neoplasms 28322989 "Several miRNAs show lowered expression in endocrine cancers (i.e. miR-200s, miR-126, miR-7, miR-29a, miR-30a, miR-137, miR-206, miR-101, miR-613, miR-539, miR-205, miR-9, miR-195), while others are commonly overexpressed (i.e. miR-21, miR-183, miR-31, miR-let7b, miR-584, miR-146b, miR-221, miR-222, miR-25, miR-595)" tissue_expression_up hsa-mir-183 Endocrine Gland Neoplasms 28322989 "Several miRNAs show lowered expression in endocrine cancers (i.e. miR-200s, miR-126, miR-7, miR-29a, miR-30a, miR-137, miR-206, miR-101, miR-613, miR-539, miR-205, miR-9, miR-195), while others are commonly overexpressed (i.e. miR-21, miR-183, miR-31, miR-let7b, miR-584, miR-146b, miR-221, miR-222, miR-25, miR-595)" tissue_expression_up hsa-mir-21 Endocrine Gland Neoplasms 28322989 "Several miRNAs show lowered expression in endocrine cancers (i.e. miR-200s, miR-126, miR-7, miR-29a, miR-30a, miR-137, miR-206, miR-101, miR-613, miR-539, miR-205, miR-9, miR-195), while others are commonly overexpressed (i.e. miR-21, miR-183, miR-31, miR-let7b, miR-584, miR-146b, miR-221, miR-222, miR-25, miR-595)" tissue_expression_up hsa-mir-221 Endocrine Gland Neoplasms 28322989 "Several miRNAs show lowered expression in endocrine cancers (i.e. miR-200s, miR-126, miR-7, miR-29a, miR-30a, miR-137, miR-206, miR-101, miR-613, miR-539, miR-205, miR-9, miR-195), while others are commonly overexpressed (i.e. miR-21, miR-183, miR-31, miR-let7b, miR-584, miR-146b, miR-221, miR-222, miR-25, miR-595)" tissue_expression_up hsa-mir-222 Endocrine Gland Neoplasms 28322989 "Several miRNAs show lowered expression in endocrine cancers (i.e. miR-200s, miR-126, miR-7, miR-29a, miR-30a, miR-137, miR-206, miR-101, miR-613, miR-539, miR-205, miR-9, miR-195), while others are commonly overexpressed (i.e. miR-21, miR-183, miR-31, miR-let7b, miR-584, miR-146b, miR-221, miR-222, miR-25, miR-595)" tissue_expression_up hsa-mir-25 Endocrine Gland Neoplasms 28322989 "Several miRNAs show lowered expression in endocrine cancers (i.e. miR-200s, miR-126, miR-7, miR-29a, miR-30a, miR-137, miR-206, miR-101, miR-613, miR-539, miR-205, miR-9, miR-195), while others are commonly overexpressed (i.e. miR-21, miR-183, miR-31, miR-let7b, miR-584, miR-146b, miR-221, miR-222, miR-25, miR-595)" tissue_expression_up hsa-mir-31 Endocrine Gland Neoplasms 28322989 "Several miRNAs show lowered expression in endocrine cancers (i.e. miR-200s, miR-126, miR-7, miR-29a, miR-30a, miR-137, miR-206, miR-101, miR-613, miR-539, miR-205, miR-9, miR-195), while others are commonly overexpressed (i.e. miR-21, miR-183, miR-31, miR-let7b, miR-584, miR-146b, miR-221, miR-222, miR-25, miR-595)" tissue_expression_up hsa-mir-584 Endocrine Gland Neoplasms 28322989 "Several miRNAs show lowered expression in endocrine cancers (i.e. miR-200s, miR-126, miR-7, miR-29a, miR-30a, miR-137, miR-206, miR-101, miR-613, miR-539, miR-205, miR-9, miR-195), while others are commonly overexpressed (i.e. miR-21, miR-183, miR-31, miR-let7b, miR-584, miR-146b, miR-221, miR-222, miR-25, miR-595)" tissue_expression_up hsa-mir-595 Endocrine Gland Neoplasms 28322989 "Several miRNAs show lowered expression in endocrine cancers (i.e. miR-200s, miR-126, miR-7, miR-29a, miR-30a, miR-137, miR-206, miR-101, miR-613, miR-539, miR-205, miR-9, miR-195), while others are commonly overexpressed (i.e. miR-21, miR-183, miR-31, miR-let7b, miR-584, miR-146b, miR-221, miR-222, miR-25, miR-595)" tissue_expression_up hsa-mir-210 Lung Neoplasms 28334118 "we found that hsa-mir-210 was upregulated, while hsa-mir-490 and hsa-mir-486 were downregulated in?>?90% of the 991 lung cancer samples" tissue_expression_up hsa-mir-888 "Carcinoma, Hepatocellular" 28337887 Up-regulation of miR-888-5p in hepatocellular carcinoma cell lines and its effect on malignant characteristics of cells. tissue_expression_up hsa-mir-137 "Carcinoma, Hepatocellular" 28350139 Upregulation of miR-137 reverses sorafenib resistance and cancer-initiating cell phenotypes by degrading ANT2 in hepatocellular carcinoma. tissue_expression_up hsa-mir-223 "Carcinoma, Gastrooesophageal" 28395057 Early miR-223 Upregulation in Gastroesophageal Carcinogenesis. tissue_expression_up hsa-let-7a "Carcinoma, Gastric" 28399984 Up-regulation of Let-7a Expression Induces Gastric Carcinoma Cell Apoptosis In Vitro. tissue_expression_up hsa-mir-21 "Fibromatosis, Aggressive" 28418912 "The correlation between sporadic DTs and miRNA expression showed that miR-21-3p increased in mutated versus wild-type DTs, while miR-197-3p was decreased" tissue_expression_up hsa-mir-93 Glioma 28440610 Evaluation Expression of Microrna-93 and Integrin ¦¢8 in Different Types of Glioma Tumors tissue_expression_up hsa-mir-182 Behcet Disease 28482290 "up regulation of miR-182 and miR-3591-3p; down regulation of miR-155, miR-638 and miR-4488 in the pathogenesis of the disease" tissue_expression_up hsa-mir-3591 Behcet Disease 28482290 "up regulation of miR-182 and miR-3591-3p; down regulation of miR-155, miR-638 and miR-4488 in the pathogenesis of the disease" tissue_expression_up hsa-mir-101 Colon Neoplasms 28560419 Upregulation of miR-101 enhances the cytotoxic effect of anticancer drugs through inhibition of colon cancer cell proliferation. tissue_expression_up hsa-mir-143 Breast Neoplasms 28588724 Upregulation of microRNA-143 reverses drug resistance in human breast cancer cells via inhibition of cytokine-induced apoptosis inhibitor 1. tissue_expression_up hsa-mir-199a Colorectal Carcinoma 28639895 Upregulation of miR-199a/b contributes to cisplatin resistance via Wnt/¦Â-catenin-ABCG2 signaling pathway in ALDHA1+ colorectal cancer stem cells. tissue_expression_up hsa-mir-199b Colorectal Carcinoma 28639895 Upregulation of miR-199a/b contributes to cisplatin resistance via Wnt/¦Â-catenin-ABCG2 signaling pathway in ALDHA1+ colorectal cancer stem cells. tissue_expression_up hsa-mir-9 "Carcinoma, Hepatocellular" 28774651 "inhibition of hsa_circ_0071410 increased the expression of miR-9-5p, resulting in the attenuation of irradiation induced HSC activation" tissue_expression_up hsa-mir-155 Systemic Lupus Erythematosus 28779021 "IFN-¦Á impairs insulin-mediated NO production, and altered gene expression resulted from eNOS instability, possibly due to enhanced miR-155 expression" tissue_expression_up hsa-mir-126 Vasomotor Rhinitis 28787742 "there was significant overexpression of miR-543, miR-129-5p, and miR-126-3p, and under-expression of miR-2110, miR-449c-5p, miR-449b-5p, miR-190b, and miR-92b-5p." tissue_expression_up hsa-mir-129 Vasomotor Rhinitis 28787742 "there was significant overexpression of miR-543, miR-129-5p, and miR-126-3p, and under-expression of miR-2110, miR-449c-5p, miR-449b-5p, miR-190b, and miR-92b-5p." tissue_expression_up hsa-mir-543 Vasomotor Rhinitis 28787742 "there was significant overexpression of miR-543, miR-129-5p, and miR-126-3p, and under-expression of miR-2110, miR-449c-5p, miR-449b-5p, miR-190b, and miR-92b-5p." tissue_expression_up hsa-mir-125a "Lymphoma, Large B-Cell, Diffuse" 28817403 "PB-DLBCL and DLBCL-GCB-CC also had much higher levels of miR-125a-3p, miR-34-3p, and miR-155-5p, and significantly lower levels of miR-17-5p and miR-17-3p" tissue_expression_up hsa-mir-155 "Lymphoma, Large B-Cell, Diffuse" 28817403 "PB-DLBCL and DLBCL-GCB-CC also had much higher levels of miR-125a-3p, miR-34-3p, and miR-155-5p, and significantly lower levels of miR-17-5p and miR-17-3p" tissue_expression_up hsa-mir-34 "Lymphoma, Large B-Cell, Diffuse" 28817403 "PB-DLBCL and DLBCL-GCB-CC also had much higher levels of miR-125a-3p, miR-34-3p, and miR-155-5p, and significantly lower levels of miR-17-5p and miR-17-3p" tissue_expression_up hsa-mir-125b Colorectal Carcinoma 28881590 Upregulation of microRNA-125b by G-CSF promotes metastasis in colorectal cancer tissue_expression_up hsa-mir-210 "Adenocarcinoma, Esophageal" 28968550 "Expression levels of miR-25 and miR-210 were significantly higher, and those of PTEN and AIFM3 significantly lower" tissue_expression_up hsa-mir-25 "Adenocarcinoma, Esophageal" 28968550 "Expression levels of miR-25 and miR-210 were significantly higher, and those of PTEN and AIFM3 significantly lower" tissue_expression_up hsa-mir-223 Chorioamnionitis 29083107 Increased miR-223 expression in foetal organs is a signature of acute chorioamnionitis with systemic consequences. tissue_expression_up hsa-mir-214 "Carcinoma, Hepatocellular" 29088870 high miR-214 could be a promising biomarker for prognosis prediction of cancer tissue_expression_up hsa-mir-21 "Carcinoma, Thyroid, Medullary" 29107050 MicroRNA-21 and long non-coding RNA MALAT1 are overexpressed markers in medullary thyroid carcinoma. tissue_expression_up hsa-mir-16 Glioblastoma 29110584 "Our data demonstrated a significant upregulation of five microRNAs (hsa-miR-16, hsa-miR-17, hsa-miR-21, hsa-miR-221, and hsa-miR-375)" tissue_expression_up hsa-mir-17 Glioblastoma 29110584 "Our data demonstrated a significant upregulation of five microRNAs (hsa-miR-16, hsa-miR-17, hsa-miR-21, hsa-miR-221, and hsa-miR-375)" tissue_expression_up hsa-mir-21 Glioblastoma 29110584 "Our data demonstrated a significant upregulation of five microRNAs (hsa-miR-16, hsa-miR-17, hsa-miR-21, hsa-miR-221, and hsa-miR-375)" tissue_expression_up hsa-mir-221 Glioblastoma 29110584 "Our data demonstrated a significant upregulation of five microRNAs (hsa-miR-16, hsa-miR-17, hsa-miR-21, hsa-miR-221, and hsa-miR-375)" tissue_expression_up hsa-mir-375 Glioblastoma 29110584 "Our data demonstrated a significant upregulation of five microRNAs (hsa-miR-16, hsa-miR-17, hsa-miR-21, hsa-miR-221, and hsa-miR-375)" tissue_expression_up hsa-mir-302c Ovarian Germ Cell Cancer 29138809 "Higher expression of miR-373-3p, miR-372-3p and miR-302c-3p and lower expression of miR-199a-5p, miR-214-5p and miR-202-3p were reproducibly observed in malignant OGCTs as compared to benign OGCTs or SCSTs" tissue_expression_up hsa-mir-372 Ovarian Germ Cell Cancer 29138809 "Higher expression of miR-373-3p, miR-372-3p and miR-302c-3p and lower expression of miR-199a-5p, miR-214-5p and miR-202-3p were reproducibly observed in malignant OGCTs as compared to benign OGCTs or SCSTs" tissue_expression_up hsa-mir-373 Ovarian Germ Cell Cancer 29138809 "Higher expression of miR-373-3p, miR-372-3p and miR-302c-3p and lower expression of miR-199a-5p, miR-214-5p and miR-202-3p were reproducibly observed in malignant OGCTs as compared to benign OGCTs or SCSTs" tissue_expression_up hsa-mir-21 Gastric Neoplasms 29142602 there was a higher expression of VEGF and miR-21 in GC tissues compared with that in morphologically adjacent normal tissues whereas PPAR¦Á expression was decreased tissue_expression_up hsa-mir-143 Myocardial Infarction 29162889 "The expression level of miR-143 in monocytes from STEMI patients compared to healthy controls was increased, whereas the expression of miR-1, -92a, -99a, and -223 was reduced significantly" tissue_expression_up hsa-mir-10a Pancreatic Neoplasms 29169171 "miR-27a, miR-27b, miR-9, miR10a and miR-10b were up-regulated in PDAC cells compared to HPDE cells" tissue_expression_up hsa-mir-10b Pancreatic Neoplasms 29169171 "miR-27a, miR-27b, miR-9, miR10a and miR-10b were up-regulated in PDAC cells compared to HPDE cells" tissue_expression_up hsa-mir-27a Pancreatic Neoplasms 29169171 "miR-27a, miR-27b, miR-9, miR10a and miR-10b were up-regulated in PDAC cells compared to HPDE cells" tissue_expression_up hsa-mir-27b Pancreatic Neoplasms 29169171 "miR-27a, miR-27b, miR-9, miR10a and miR-10b were up-regulated in PDAC cells compared to HPDE cells" tissue_expression_up hsa-mir-9 Pancreatic Neoplasms 29169171 "miR-27a, miR-27b, miR-9, miR10a and miR-10b were up-regulated in PDAC cells compared to HPDE cells" tissue_expression_up hsa-mir-181a Adenosquamous Pancreas Carcinoma 29221165 "Furthermore, lower Ang-1 and Tie-2 transcript levels and higher increases of miR-21-5p, miR27a-3p and miR-181a-5p levels were found in the rarest form of pancreatic carcinoma." tissue_expression_up hsa-mir-21 Adenosquamous Pancreas Carcinoma 29221165 "Furthermore, lower Ang-1 and Tie-2 transcript levels and higher increases of miR-21-5p, miR27a-3p and miR-181a-5p levels were found in the rarest form of pancreatic carcinoma." tissue_expression_up hsa-mir-27a Adenosquamous Pancreas Carcinoma 29221165 "Furthermore, lower Ang-1 and Tie-2 transcript levels and higher increases of miR-21-5p, miR27a-3p and miR-181a-5p levels were found in the rarest form of pancreatic carcinoma." tissue_expression_up hsa-mir-155 Congenital Heart Diseases 29281614 "Mir-486-3p, mir-486-5p, and mir-155-5p increased in patients with cyanotic heart disease compared with those without heart disease" tissue_expression_up hsa-mir-486 Congenital Heart Diseases 29281614 "Mir-486-3p, mir-486-5p, and mir-155-5p increased in patients with cyanotic heart disease compared with those without heart disease" tissue_expression_up hsa-mir-10b "Carcinoma, Hepatocellular" 29314614 "miR-1, miR-122, let-7a, and let-7g were downregulated, whereas miR-10b and miR-21 were upregulated in canine HCC" tissue_expression_up hsa-mir-21 "Carcinoma, Hepatocellular" 29314614 "miR-1, miR-122, let-7a, and let-7g were downregulated, whereas miR-10b and miR-21 were upregulated in canine HCC" tissue_expression_up hsa-mir-143 NUT Midline Carcinoma 29322795 "All NMCs showed upregulation of miR-9 and downregulation of miR-99a and miR-145 and two cases featured also upregulation of miR-21, miR-143, and miR-484" tissue_expression_up hsa-mir-21 NUT Midline Carcinoma 29322795 "All NMCs showed upregulation of miR-9 and downregulation of miR-99a and miR-145 and two cases featured also upregulation of miR-21, miR-143, and miR-484" tissue_expression_up hsa-mir-484 NUT Midline Carcinoma 29322795 "All NMCs showed upregulation of miR-9 and downregulation of miR-99a and miR-145 and two cases featured also upregulation of miR-21, miR-143, and miR-484" tissue_expression_up hsa-mir-9 NUT Midline Carcinoma 29322795 "All NMCs showed upregulation of miR-9 and downregulation of miR-99a and miR-145 and two cases featured also upregulation of miR-21, miR-143, and miR-485" tissue_expression_up hsa-mir-122 Hepatitis C Virus Infection 29359389 "MicroRNAs associated with HCV-related immunopathogenesis which were found to be enriched in exosomes of HCV viremic patients (in particular, miR-122-5p, miR-222-3p, miR-146a, miR-150-5p, miR-30c, miR-378a-3p and miR-20a-5p) were markedly reduced by DAA therapy" tissue_expression_up hsa-mir-146a Hepatitis C Virus Infection 29359389 "MicroRNAs associated with HCV-related immunopathogenesis which were found to be enriched in exosomes of HCV viremic patients (in particular, miR-122-5p, miR-222-3p, miR-146a, miR-150-5p, miR-30c, miR-378a-3p and miR-20a-5p) were markedly reduced by DAA therapy" tissue_expression_up hsa-mir-150 Hepatitis C Virus Infection 29359389 "MicroRNAs associated with HCV-related immunopathogenesis which were found to be enriched in exosomes of HCV viremic patients (in particular, miR-122-5p, miR-222-3p, miR-146a, miR-150-5p, miR-30c, miR-378a-3p and miR-20a-5p) were markedly reduced by DAA therapy" tissue_expression_up hsa-mir-20a Hepatitis C Virus Infection 29359389 "MicroRNAs associated with HCV-related immunopathogenesis which were found to be enriched in exosomes of HCV viremic patients (in particular, miR-122-5p, miR-222-3p, miR-146a, miR-150-5p, miR-30c, miR-378a-3p and miR-20a-5p) were markedly reduced by DAA therapy" tissue_expression_up hsa-mir-222 Hepatitis C Virus Infection 29359389 "MicroRNAs associated with HCV-related immunopathogenesis which were found to be enriched in exosomes of HCV viremic patients (in particular, miR-122-5p, miR-222-3p, miR-146a, miR-150-5p, miR-30c, miR-378a-3p and miR-20a-5p) were markedly reduced by DAA therapy" tissue_expression_up hsa-mir-30c Hepatitis C Virus Infection 29359389 "MicroRNAs associated with HCV-related immunopathogenesis which were found to be enriched in exosomes of HCV viremic patients (in particular, miR-122-5p, miR-222-3p, miR-146a, miR-150-5p, miR-30c, miR-378a-3p and miR-20a-5p) were markedly reduced by DAA therapy" tissue_expression_up hsa-mir-378a Hepatitis C Virus Infection 29359389 "MicroRNAs associated with HCV-related immunopathogenesis which were found to be enriched in exosomes of HCV viremic patients (in particular, miR-122-5p, miR-222-3p, miR-146a, miR-150-5p, miR-30c, miR-378a-3p and miR-20a-5p) were markedly reduced by DAA therapy" tissue_expression_up hsa-mir-183 "Carcinoma, Thyroid, Medullary" 29388012 Tumour expression levels of miR-21 (p=0.0008) and miR-183 (p=0.0096) were higher in the LNI group tissue_expression_up hsa-mir-21 "Carcinoma, Thyroid, Medullary" 29388012 Tumour expression levels of miR-21 (p=0.0008) and miR-183 (p=0.0097) were higher in the LNI group tissue_expression_up hsa-mir-150 Infection [unspecific] 29391047 "upregulated miR-21, miR-155, miR-150, and miR-221, as well as downregulated miR-143 and miR-125, all of them previously linked to other bacterial infections" tissue_expression_up hsa-mir-155 Infection [unspecific] 29391047 "upregulated miR-21, miR-155, miR-150, and miR-221, as well as downregulated miR-143 and miR-125, all of them previously linked to other bacterial infections" tissue_expression_up hsa-mir-21 Infection [unspecific] 29391047 "upregulated miR-21, miR-155, miR-150, and miR-221, as well as downregulated miR-143 and miR-125, all of them previously linked to other bacterial infections" tissue_expression_up hsa-mir-221 Infection [unspecific] 29391047 "upregulated miR-21, miR-155, miR-150, and miR-221, as well as downregulated miR-143 and miR-125, all of them previously linked to other bacterial infections" tissue_expression_up hsa-mir-142 "Carcinoma, Renal Cell" 29440068 "miR-21, miR-142-3p, miR-142-5p, miR-150, and miR-155 as significantly upregulated" tissue_expression_up hsa-mir-150 "Carcinoma, Renal Cell" 29440068 "miR-21, miR-142-3p, miR-142-5p, miR-150, and miR-155 as significantly upregulated" tissue_expression_up hsa-mir-155 "Carcinoma, Renal Cell" 29440068 "miR-21, miR-142-3p, miR-142-5p, miR-150, and miR-155 as significantly upregulated" tissue_expression_up hsa-mir-21 "Carcinoma, Renal Cell" 29440068 "miR-21, miR-142-3p, miR-142-5p, miR-150, and miR-155 as significantly upregulated" tissue_expression_up hsa-mir-129-2 "Squamous Cell Carcinoma, Head and Neck" 29455435 two namely Hsa-miR-129-2-3p and Hsa-miR-449a were found to be up-regulated as compared to HPV -ve cells tissue_expression_up hsa-mir-449a "Squamous Cell Carcinoma, Head and Neck" 29455435 two namely Hsa-miR-129-2-3p and Hsa-miR-449a were found to be up-regulated as compared to HPV -ve cells tissue_expression_up hsa-let-7b Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-let-7e Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-1228 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-144 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-195 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-203 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-30b Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-32 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-340 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-345 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-34a Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-423 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-483 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-582 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-584 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-595 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-615 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-7-1 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-885 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-9 Pleural Mesothelioma 29462963 "They reported 12 over-expressed miRNAs (let-7b*, miR-1228*, miR-195*, miR-30b*, miR-32*, miR-345, miR-483-3p, miR-584, miR-595, miR-615-3p, and miR-885-3p) and nine sub-expressed (let-7e*, miR-144*, miR-203, miR-340*, miR-34a*, miR-423, miR-582, miR-7-1* and miR-9) in MPM tissue compared to the single control" tissue_expression_up hsa-mir-181d "Carcinoma, Adenoid Cystic" 29467480 hsa-miR-455-5p and hsa-miR-181d-5p were upregulated in carcinomas of both salivary and lacrimal gland tissue_expression_up hsa-mir-455 "Carcinoma, Adenoid Cystic" 29467480 hsa-miR-455-5p and hsa-miR-181d-5p were upregulated in carcinomas of both salivary and lacrimal gland tissue_expression_up hsa-mir-21 "Squamous Cell Carcinoma, Oral" 29480379 increased miR-21 levels in conjunction with decreased miR-125a levels in saliva of OLP patients may be indicative for a poor prognosis tissue_expression_up hsa-mir-21 Cervical Neoplasms 29487007 "MiR-21-5p upregulation, miR-34a downregulation, and hTERC amplification were associated with the aggressive progression of CC, which suggests that miR-21-5p, miR-34a and hTERC might serve as surrogate markers for CC progression and potential molecular targets for blockage of the development of CC" tissue_expression_up hsa-mir-182 Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_up hsa-mir-183 Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_up hsa-mir-200b Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_up hsa-mir-205 Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_up hsa-mir-21 Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_up hsa-mir-210 Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_up hsa-mir-31 Lung Neoplasms 29516903 "the authors identified a statistically significant miRNA meta-signature of seven upregulated (miR-21, miR-210, miR-182, miR-31, miR-200b, miR-205, and miR-183) and eight downregulated (miR-126-3p, miR-30a, miR-30d, miR-486-5p, miR-451a, miR-126-5p, miR-143, and miR-145) miRNAs" tissue_expression_up hsa-mir-141 Ovarian Neoplasms 29518404 "Specifically, miR-196b, miR-532, miR-886-3b, and miR-99b exhibited lower levels in HGOSC compared with USC, whereas miR-29c, miR-155, miR-454, miR-146b-5p, miR-486-5p, miR-27a, miR-192, and miR-141 exhibited significantly higher expression in HGOSC samples" tissue_expression_up hsa-mir-146b Ovarian Neoplasms 29518404 "Specifically, miR-196b, miR-532, miR-886-3b, and miR-99b exhibited lower levels in HGOSC compared with USC, whereas miR-29c, miR-155, miR-454, miR-146b-5p, miR-486-5p, miR-27a, miR-192, and miR-141 exhibited significantly higher expression in HGOSC samples" tissue_expression_up hsa-mir-155 Ovarian Neoplasms 29518404 "Specifically, miR-196b, miR-532, miR-886-3b, and miR-99b exhibited lower levels in HGOSC compared with USC, whereas miR-29c, miR-155, miR-454, miR-146b-5p, miR-486-5p, miR-27a, miR-192, and miR-141 exhibited significantly higher expression in HGOSC samples" tissue_expression_up hsa-mir-192 Ovarian Neoplasms 29518404 "Specifically, miR-196b, miR-532, miR-886-3b, and miR-99b exhibited lower levels in HGOSC compared with USC, whereas miR-29c, miR-155, miR-454, miR-146b-5p, miR-486-5p, miR-27a, miR-192, and miR-141 exhibited significantly higher expression in HGOSC samples" tissue_expression_up hsa-mir-27a Ovarian Neoplasms 29518404 "Specifically, miR-196b, miR-532, miR-886-3b, and miR-99b exhibited lower levels in HGOSC compared with USC, whereas miR-29c, miR-155, miR-454, miR-146b-5p, miR-486-5p, miR-27a, miR-192, and miR-141 exhibited significantly higher expression in HGOSC samples" tissue_expression_up hsa-mir-29c Ovarian Neoplasms 29518404 "Specifically, miR-196b, miR-532, miR-886-3b, and miR-99b exhibited lower levels in HGOSC compared with USC, whereas miR-29c, miR-155, miR-454, miR-146b-5p, miR-486-5p, miR-27a, miR-192, and miR-141 exhibited significantly higher expression in HGOSC samples" tissue_expression_up hsa-mir-454 Ovarian Neoplasms 29518404 "Specifically, miR-196b, miR-532, miR-886-3b, and miR-99b exhibited lower levels in HGOSC compared with USC, whereas miR-29c, miR-155, miR-454, miR-146b-5p, miR-486-5p, miR-27a, miR-192, and miR-141 exhibited significantly higher expression in HGOSC samples" tissue_expression_up hsa-mir-486 Ovarian Neoplasms 29518404 "Specifically, miR-196b, miR-532, miR-886-3b, and miR-99b exhibited lower levels in HGOSC compared with USC, whereas miR-29c, miR-155, miR-454, miR-146b-5p, miR-486-5p, miR-27a, miR-192, and miR-141 exhibited significantly higher expression in HGOSC samples" tissue_expression_up hsa-mir-1246 "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_up hsa-mir-155 "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_up hsa-mir-181 "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_up hsa-mir-196a "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_up hsa-mir-21 "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_up hsa-mir-29b "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_up hsa-mir-372 "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_up hsa-mir-373 "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_up hsa-mir-455 "Squamous Cell Carcinoma, Oral" 29533734 "Poor prognosis correlated with upregulation of 9 miRNAs (miR-21, miR-455-5p, miiR-155-5p, miR-372, miR-373, miR-29b, miR-1246, miR-196a, and miR-181) and downregulation of 7 miRNAs (miR-204, miR-101, miR-32, miR-20a, miR-16, miR-17, and miR-125b)" tissue_expression_up hsa-mir-125b Glioblastoma 29538610 "Upregulation of miR-125b, miR-181d, and miR-221 Predicts Poor Prognosis in MGMT Promoter-Unmethylated Glioblastoma Patients" tissue_expression_up hsa-mir-181d Glioblastoma 29538610 "Upregulation of miR-125b, miR-181d, and miR-221 Predicts Poor Prognosis in MGMT Promoter-Unmethylated Glioblastoma Patients" tissue_expression_up hsa-mir-221 Glioblastoma 29538610 "Upregulation of miR-125b, miR-181d, and miR-221 Predicts Poor Prognosis in MGMT Promoter-Unmethylated Glioblastoma Patients" tissue_expression_up hsa-mir-320 Osteonecrosis 29551500 Upregulation of microRNA-320 decreases the risk of developing steroid-induced avascular necrosis of femoral head by inhibiting CYP1A2 both in vivo and in vitro. tissue_expression_up hsa-mir-21 Glioblastoma 29559295 "In our microarray data, lower expression of miR-219-5p, miR-124, and miR-128 and higher expression of miR-21 was observed in GBM compared with the peripheral region, similar to the results of previous reports" tissue_expression_up hsa-mir-155 "Scleroderma, Systemic" 29559981 "miR-21-5p, miR-92a-3p, miR-155-5p, and miR-16-5p expression was significantly higher in SSc sera compared to healthy controls" tissue_expression_up hsa-mir-16 "Scleroderma, Systemic" 29559981 "miR-21-5p, miR-92a-3p, miR-155-5p, and miR-16-5p expression was significantly higher in SSc sera compared to healthy controls" tissue_expression_up hsa-mir-21 "Scleroderma, Systemic" 29559981 "miR-21-5p, miR-92a-3p, miR-155-5p, and miR-16-5p expression was significantly higher in SSc sera compared to healthy controls" tissue_expression_up hsa-mir-92a "Scleroderma, Systemic" 29559981 "miR-21-5p, miR-92a-3p, miR-155-5p, and miR-16-5p expression was significantly higher in SSc sera compared to healthy controls" tissue_expression_up hsa-mir-127 Prostate Neoplasms 29568403 "The top 11 miRNAs with significantly higher level in ExoHypoxic compared to ExoNormoxic were miR-517a, miR-204, miR-885, miR-143, miR-335, miR-127, miR-542, miR-433, miR-451, miR-92a and miR-186a" tissue_expression_up hsa-mir-143 Prostate Neoplasms 29568403 "The top 11 miRNAs with significantly higher level in ExoHypoxic compared to ExoNormoxic were miR-517a, miR-204, miR-885, miR-143, miR-335, miR-127, miR-542, miR-433, miR-451, miR-92a and miR-184a" tissue_expression_up hsa-mir-181a Prostate Neoplasms 29568403 "The top 11 miRNAs with significantly higher level in ExoHypoxic compared to ExoNormoxic were miR-517a, miR-204, miR-885, miR-143, miR-335, miR-127, miR-542, miR-433, miR-451, miR-92a and miR-191a" tissue_expression_up hsa-mir-204 Prostate Neoplasms 29568403 "The top 11 miRNAs with significantly higher level in ExoHypoxic compared to ExoNormoxic were miR-517a, miR-204, miR-885, miR-143, miR-335, miR-127, miR-542, miR-433, miR-451, miR-92a and miR-182a" tissue_expression_up hsa-mir-335 Prostate Neoplasms 29568403 "The top 11 miRNAs with significantly higher level in ExoHypoxic compared to ExoNormoxic were miR-517a, miR-204, miR-885, miR-143, miR-335, miR-127, miR-542, miR-433, miR-451, miR-92a and miR-185a" tissue_expression_up hsa-mir-433 Prostate Neoplasms 29568403 "The top 11 miRNAs with significantly higher level in ExoHypoxic compared to ExoNormoxic were miR-517a, miR-204, miR-885, miR-143, miR-335, miR-127, miR-542, miR-433, miR-451, miR-92a and miR-188a" tissue_expression_up hsa-mir-451 Prostate Neoplasms 29568403 "The top 11 miRNAs with significantly higher level in ExoHypoxic compared to ExoNormoxic were miR-517a, miR-204, miR-885, miR-143, miR-335, miR-127, miR-542, miR-433, miR-451, miR-92a and miR-189a" tissue_expression_up hsa-mir-517a Prostate Neoplasms 29568403 "The top 11 miRNAs with significantly higher level in ExoHypoxic compared to ExoNormoxic were miR-517a, miR-204, miR-885, miR-143, miR-335, miR-127, miR-542, miR-433, miR-451, miR-92a and miR-181a" tissue_expression_up hsa-mir-542 Prostate Neoplasms 29568403 "The top 11 miRNAs with significantly higher level in ExoHypoxic compared to ExoNormoxic were miR-517a, miR-204, miR-885, miR-143, miR-335, miR-127, miR-542, miR-433, miR-451, miR-92a and miR-187a" tissue_expression_up hsa-mir-885 Prostate Neoplasms 29568403 "The top 11 miRNAs with significantly higher level in ExoHypoxic compared to ExoNormoxic were miR-517a, miR-204, miR-885, miR-143, miR-335, miR-127, miR-542, miR-433, miR-451, miR-92a and miR-183a" tissue_expression_up hsa-mir-92a Prostate Neoplasms 29568403 "The top 11 miRNAs with significantly higher level in ExoHypoxic compared to ExoNormoxic were miR-517a, miR-204, miR-885, miR-143, miR-335, miR-127, miR-542, miR-433, miR-451, miR-92a and miR-190a" tissue_expression_up hsa-mir-145 "Carcinoma, Ovarian" 29569698 miRNA-145 expression was lower in DPEEOC endometrial tissues and higher in DPEEOC ovarian tissues compared to the corresponding normal tissues tissue_expression_up hsa-mir-373 "Squamous Cell Carcinoma, Esophageal" 29578163 "Upregulation of miR-371-373 cluster, a human embryonic stem cell specific microRNA cluster, in esophageal squamous cell carcinoma" tissue_expression_up hsa-let-7a Pancreatic Neoplasms 29596326 These effects were associated with increases in the expression of let-7a microRNA; suppression of K-Ras and survivin; and the elimination of drug-resistant cancer stem/tumor-initiating cells tissue_expression_up hsa-mir-20a Breast Neoplasms 29617404 "Our results suggest a role for miR-20a in the regulation of breast cancer angiogenesis, and raise the possibility of its use as an angiogenic biomarker" tissue_expression_up hsa-mir-10a Urinary System Cancer 29623292 the decline of miR-145 expression level have been proved to be able to distinguish bladder cancer patients from non-cancer controls in cell-free urine samples5; the elevation of miR-10a and miR-30d was also observed in urine samples from patients with focal segmental glomerulosclerosis tissue_expression_up hsa-mir-30d Urinary System Cancer 29623292 the decline of miR-145 expression level have been proved to be able to distinguish bladder cancer patients from non-cancer controls in cell-free urine samples5; the elevation of miR-10a and miR-30d was also observed in urine samples from patients with focal segmental glomerulosclerosis tissue_expression_up hsa-mir-155 Atherosclerosis 29642385 Exposure to the high dose of CS also significantly upregulated the miRNA-155 level in the aortic tissues of ApoE KO mice tissue_expression_up hsa-mir-155 Myocardial Infarction 29642385 Exposure to the high dose of CS also significantly upregulated the miRNA-155 level in the aortic tissues of ApoE KO mice tissue_expression_up hsa-mir-155 Stroke 29642385 Exposure to the high dose of CS also significantly upregulated the miRNA-155 level in the aortic tissues of ApoE KO mice tissue_expression_up hsa-mir-21 Atherosclerosis 29642385 "Moreover, the expression level of miR-126 tended to be downregulated and that of miR-21 tended to be upregulated in ApoE KO mice exposed to the high dose of CS, albeit statistically insignificant" tissue_expression_up hsa-mir-21 Myocardial Infarction 29642385 "Moreover, the expression level of miR-126 tended to be downregulated and that of miR-21 tended to be upregulated in ApoE KO mice exposed to the high dose of CS, albeit statistically insignificant" tissue_expression_up hsa-mir-21 Stroke 29642385 "Moreover, the expression level of miR-126 tended to be downregulated and that of miR-21 tended to be upregulated in ApoE KO mice exposed to the high dose of CS, albeit statistically insignificant" tissue_expression_up hsa-mir-101 Medulloblastoma 29658967 "Low-expression of miR-221, miR-9, and miR-181c/d and over-expression of miR-101, miR-222, miR-139, miR-1827, and miR-34c was found in medulloblastoma" tissue_expression_up hsa-mir-10b Ependymoma 29658967 low expression of miR-10a and over-expression of miR-10b and miR-29a in ependymoma tissue_expression_up hsa-mir-139 Medulloblastoma 29658967 "Low-expression of miR-221, miR-9, and miR-181c/d and over-expression of miR-101, miR-222, miR-139, miR-1827, and miR-34c was found in medulloblastoma" tissue_expression_up hsa-mir-1827 Medulloblastoma 29658967 "Low-expression of miR-221, miR-9, and miR-181c/d and over-expression of miR-101, miR-222, miR-139, miR-1827, and miR-34c was found in medulloblastoma" tissue_expression_up hsa-mir-19a Glioma 29658967 "low expression of miR-26a and overexpression of miR-19a/b, miR-24, miR-27a, miR- 584, and miR-528 in low-grade glioma" tissue_expression_up hsa-mir-19b Glioma 29658967 "low expression of miR-26a and overexpression of miR-19a/b, miR-24, miR-27a, miR- 584, and miR-529 in low-grade glioma" tissue_expression_up hsa-mir-222 Medulloblastoma 29658967 "Low-expression of miR-221, miR-9, and miR-181c/d and over-expression of miR-101, miR-222, miR-139, miR-1827, and miR-34c was found in medulloblastoma" tissue_expression_up hsa-mir-24 Glioma 29658967 "low expression of miR-26a and overexpression of miR-19a/b, miR-24, miR-27a, miR- 584, and miR-530 in low-grade glioma" tissue_expression_up hsa-mir-27a Glioma 29658967 "low expression of miR-26a and overexpression of miR-19a/b, miR-24, miR-27a, miR- 584, and miR-531 in low-grade glioma" tissue_expression_up hsa-mir-29a Ependymoma 29658967 low expression of miR-10a and over-expression of miR-10b and miR-29a in ependymoma tissue_expression_up hsa-mir-34c Medulloblastoma 29658967 "Low-expression of miR-221, miR-9, and miR-181c/d and over-expression of miR-101, miR-222, miR-139, miR-1827, and miR-34c was found in medulloblastoma" tissue_expression_up hsa-mir-527 Glioma 29658967 "low expression of miR-26a and overexpression of miR-19a/b, miR-24, miR-27a, miR- 584, and miR-533 in low-grade glioma" tissue_expression_up hsa-mir-584 Glioma 29658967 "low expression of miR-26a and overexpression of miR-19a/b, miR-24, miR-27a, miR- 584, and miR-532 in low-grade glioma" tissue_expression_up hsa-mir-155 Down Syndrome 29661714 microRNA 155 up regulation in the CNS is strongly correlated to Down's syndrome dementia. tissue_expression_up hsa-mir-124 Non Specific Chronic Endometritis 29663566 "MiR-27a-3p and miR-124-3p, upregulated in endometrium and serum from women affected by Chronic Endometritis, are new potential molecular markers of endometrial receptivity." tissue_expression_up hsa-mir-27a Non Specific Chronic Endometritis 29663566 "MiR-27a-3p and miR-124-3p, upregulated in endometrium and serum from women affected by Chronic Endometritis, are new potential molecular markers of endometrial receptivity." tissue_expression_up hsa-mir-125b "Squamous Cell Carcinoma, Head and Neck" 29667275 "miR-26 and miR-125b may be associated with the progression and metastasis of HNSCC, and that miR-203 is associated with a more favourable prognosis." tissue_expression_up hsa-mir-26 "Squamous Cell Carcinoma, Head and Neck" 29667275 "miR-26 and miR-125b may be associated with the progression and metastasis of HNSCC, and that miR-203 is associated with a more favourable prognosis." tissue_expression_up hsa-mir-375 "Carcinoma, Thyroid, Follicular" 29683529 High expression values of MirR-375 provided 100% ROM tissue_expression_up hsa-mir-133a "Carcinoma, Breast" 29698983 high responders exhibited increased miR-133a-3p and a borderline statistically significant increase in miR-370-3p tissue_expression_up hsa-mir-370a "Carcinoma, Breast" 29698983 high responders exhibited increased miR-133a-3p and a borderline statistically significant increase in miR-370-3p tissue_expression_up hsa-mir-18a Osteonecrosis 29700584 Bioinformatics genetic network analysis focusing on the six miRNAs found the upregulated miR-18a and miR-19a are associated with angiogenesis after induction of ischemia tissue_expression_up hsa-mir-19a Osteonecrosis 29700584 Bioinformatics genetic network analysis focusing on the six miRNAs found the upregulated miR-18a and miR-19a are associated with angiogenesis after induction of ischemia tissue_expression_up hsa-mir-21 "Adenocarcinoma, Ampullary" 29731265 MiR-21 up-regulation in ampullary adenocarcinoma and its pre-invasive lesions. tissue_expression_up hsa-mir-467d Alcoholic Cardiomyopathy 29734191 The results demonstrated that miR-467d-3p and miR-491-5p were up-regulated and miR-3098-3p was down-regulated in the alcohol-exposed myocardial samples compared with the control samples (P < 0.05). tissue_expression_up hsa-mir-491 Alcoholic Cardiomyopathy 29734191 The results demonstrated that miR-467d-3p and miR-491-5p were up-regulated and miR-3098-3p was down-regulated in the alcohol-exposed myocardial samples compared with the control samples (P < 0.05). tissue_expression_up hsa-mir-223 "Carcinoma, Cervical" 29737570 the low expression of miR-188 and high expression of miR-223 correlated with the short survival of CC patients tissue_expression_up hsa-mir-92b Cholangiocarcinoma 29749758 The high level of miR-92b was associated with adverse outcomes in cholangiocarcinoma patients tissue_expression_up hsa-mir-203 "Carcinoma, Breast" 29750301 Sevoflurane suppresses proliferation by upregulating microRNA-203 in breast cancer cells. tissue_expression_up hsa-mir-140 Fatty Liver [unspecific] 29751019 "the expression of Rev-erb¦Á-targeting miRNAs, miR-140-5p, 185-5p, 326-5p and 328-5p were increased in this group." tissue_expression_up hsa-mir-185 Fatty Liver [unspecific] 29751019 "the expression of Rev-erb¦Á-targeting miRNAs, miR-140-5p, 185-5p, 326-5p and 328-5p were increased in this group." tissue_expression_up hsa-mir-326 Fatty Liver [unspecific] 29751019 "the expression of Rev-erb¦Á-targeting miRNAs, miR-140-5p, 185-5p, 326-5p and 328-5p were increased in this group." tissue_expression_up hsa-mir-328 Fatty Liver [unspecific] 29751019 "the expression of Rev-erb¦Á-targeting miRNAs, miR-140-5p, 185-5p, 326-5p and 328-5p were increased in this group." tissue_expression_up hsa-mir-139 Chronic Obstructive Pulmonary Disease 29757677 "expression levels of miR-98, miR-139-5p, miR-146b-5p, and miR-451 were upregulated, as compared with NS. In contrast, miR-197, miR-204, miR-485-3p, and miR-627 were downregulated." tissue_expression_up hsa-mir-146b Chronic Obstructive Pulmonary Disease 29757677 "expression levels of miR-98, miR-139-5p, miR-146b-5p, and miR-451 were upregulated, as compared with NS. In contrast, miR-197, miR-204, miR-485-3p, and miR-627 were downregulated." tissue_expression_up hsa-mir-451 Chronic Obstructive Pulmonary Disease 29757677 "expression levels of miR-98, miR-139-5p, miR-146b-5p, and miR-451 were upregulated, as compared with NS. In contrast, miR-197, miR-204, miR-485-3p, and miR-627 were downregulated." tissue_expression_up hsa-mir-98 Chronic Obstructive Pulmonary Disease 29757677 "expression levels of miR-98, miR-139-5p, miR-146b-5p, and miR-451 were upregulated, as compared with NS. In contrast, miR-197, miR-204, miR-485-3p, and miR-627 were downregulated." tissue_expression_up hsa-mir-21 "Squamous Cell Carcinoma, Oral" 29764807 "Upregulation of miR-31 and miR-21 and downregulation of miR-99a, let-7c, miR-125b, and miR-100 were found between OSCC and controls" tissue_expression_up hsa-mir-31 "Squamous Cell Carcinoma, Oral" 29764807 "Upregulation of miR-31 and miR-21 and downregulation of miR-99a, let-7c, miR-125b, and miR-100 were found between OSCC and controls" tissue_expression_up hsa-mir-3666 Colorectal Carcinoma 29772445 The protective role of all-transretinoic acid (ATRA) against colorectal cancer development is achieved via increasing miR-3666 expression and decreasing E2F7 expression. tissue_expression_up hsa-mir-19 Gastric Neoplasms 29797599 "Our data showed that miR-146, miR-375, and Let-7 were down-regulated and miR-19 and miR-21 were up-regulated in GC patients with H. pylori infection" tissue_expression_up hsa-mir-21 Gastric Neoplasms 29797599 "Our data showed that miR-146, miR-375, and Let-7 were down-regulated and miR-19 and miR-21 were up-regulated in GC patients with H. pylori infection" tissue_expression_up hsa-mir-451 Placenta Cancer 29805755 "The results showed that miR-451 and miR-720, highly expressed placental miRNAs, presented very low or undetectable expression in cancer cell lines compared to the normal placenta and healthy tissues" tissue_expression_up hsa-mir-720 Placenta Cancer 29805755 "The results showed that miR-451 and miR-720, highly expressed placental miRNAs, presented very low or undetectable expression in cancer cell lines compared to the normal placenta and healthy tissues" tissue_expression_up hsa-let-7a "Adenocarcinoma, Lung" 29806739 miR-126 (P < 0.001) and Let-7a (P = 0.015) levels were significantly higher in the BAL fluid of lung adenocarcinoma patients than in control subjects tissue_expression_up hsa-mir-126 "Adenocarcinoma, Lung" 29806739 miR-126 (P < 0.001) and Let-7a (P = 0.015) levels were significantly higher in the BAL fluid of lung adenocarcinoma patients than in control subjects tissue_expression_up hsa-mir-324 Lung Neoplasms 29844840 The data revealed that miR-324-5p and -3p were significantly overexpressed in lung cancer cells tissue_expression_up hsa-mir-106b Gastric Neoplasms 29859516 "Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer" tissue_expression_up hsa-mir-21 Gastric Neoplasms 29859516 "Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer" tissue_expression_up hsa-mir-25 Gastric Neoplasms 29859516 "Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer" tissue_expression_up hsa-mir-93 Gastric Neoplasms 29859516 "Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer" tissue_expression_up hsa-mir-17 Colorectal Carcinoma 29902577 Early metastatic colorectal cancers show increased tissue expression of miR-17/92 cluster members in the invasive tumor front. tissue_expression_up hsa-mir-18 Colorectal Carcinoma 29902577 Early metastatic colorectal cancers show increased tissue expression of miR-17/92 cluster members in the invasive tumor front. tissue_expression_up hsa-mir-19a Colorectal Carcinoma 29902577 Early metastatic colorectal cancers show increased tissue expression of miR-17/92 cluster members in the invasive tumor front. tissue_expression_up hsa-mir-19b-1 Colorectal Carcinoma 29902577 Early metastatic colorectal cancers show increased tissue expression of miR-17/92 cluster members in the invasive tumor front. tissue_expression_up hsa-mir-20a Colorectal Carcinoma 29902577 Early metastatic colorectal cancers show increased tissue expression of miR-17/92 cluster members in the invasive tumor front. tissue_expression_up hsa-mir-92-1 Colorectal Carcinoma 29902577 Early metastatic colorectal cancers show increased tissue expression of miR-17/92 cluster members in the invasive tumor front. tissue_expression_up hsa-mir-192 Barrett Esophagus 29906417 "The miRNAs with the greatest increases in BE tissues (7.9-fold increase in expression or more, P < .0001: MIR196a, MIR192, MIR194, and MIR215) each identified BE vs control tissues" tissue_expression_up hsa-mir-194 Barrett Esophagus 29906417 "The miRNAs with the greatest increases in BE tissues (7.9-fold increase in expression or more, P < .0001: MIR196a, MIR192, MIR194, and MIR215) each identified BE vs control tissues" tissue_expression_up hsa-mir-196a Barrett Esophagus 29906417 "The miRNAs with the greatest increases in BE tissues (7.9-fold increase in expression or more, P < .0001: MIR196a, MIR192, MIR194, and MIR215) each identified BE vs control tissues" tissue_expression_up hsa-mir-215 Barrett Esophagus 29906417 "The miRNAs with the greatest increases in BE tissues (7.9-fold increase in expression or more, P < .0001: MIR196a, MIR192, MIR194, and MIR215) each identified BE vs control tissues" tissue_expression_up hsa-mir-142 Chronic Kidney Disease 29909697 "We recognized in both meta-analysis approaches a significant miRNA meta-signature of five up-regulated (miR-142-3p, miR-223-3p, miR-21-5p, miR-142-5p and miR-214-3p) and two down-regulated (miR-29c-3p and miR-200a-3p) miRNAs" tissue_expression_up hsa-mir-21 Chronic Kidney Disease 29909697 "We recognized in both meta-analysis approaches a significant miRNA meta-signature of five up-regulated (miR-142-3p, miR-223-3p, miR-21-5p, miR-142-5p and miR-214-3p) and two down-regulated (miR-29c-3p and miR-200a-3p) miRNAs" tissue_expression_up hsa-mir-214 Chronic Kidney Disease 29909697 "We recognized in both meta-analysis approaches a significant miRNA meta-signature of five up-regulated (miR-142-3p, miR-223-3p, miR-21-5p, miR-142-5p and miR-214-3p) and two down-regulated (miR-29c-3p and miR-200a-3p) miRNAs" tissue_expression_up hsa-mir-223 Chronic Kidney Disease 29909697 "We recognized in both meta-analysis approaches a significant miRNA meta-signature of five up-regulated (miR-142-3p, miR-223-3p, miR-21-5p, miR-142-5p and miR-214-3p) and two down-regulated (miR-29c-3p and miR-200a-3p) miRNAs" tissue_expression_up hsa-mir-10b "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_up hsa-mir-21 "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_up hsa-mir-221 "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_up hsa-mir-222 "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_up hsa-mir-29 "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_up hsa-mir-373 "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_up hsa-mir-9 "Carcinoma, Breast, Triple Negative" 29923083 "(1) upregulated: miR-10b, miR-21, miR-29, miR-9, miR-221/222, miR-373 or (2) downregulated: miR-145, miR-199a-5p, miR-200 family, miR-203, miR-205 in TNBC" tissue_expression_up hsa-mir-210 Neuroendocrine Tumors 29983867 "NEN metastases were associated with elevated levels of miR-30a-5p, miR-210, miR-339-3p, miR-345 and miR-660" tissue_expression_up hsa-mir-30a Neuroendocrine Tumors 29983867 "NEN metastases were associated with elevated levels of miR-30a-5p, miR-210, miR-339-3p, miR-345 and miR-660" tissue_expression_up hsa-mir-339 Neuroendocrine Tumors 29983867 "NEN metastases were associated with elevated levels of miR-30a-5p, miR-210, miR-339-3p, miR-345 and miR-660" tissue_expression_up hsa-mir-345 Neuroendocrine Tumors 29983867 "NEN metastases were associated with elevated levels of miR-30a-5p, miR-210, miR-339-3p, miR-345 and miR-660" tissue_expression_up hsa-mir-660 Neuroendocrine Tumors 29983867 "NEN metastases were associated with elevated levels of miR-30a-5p, miR-210, miR-339-3p, miR-345 and miR-660" tissue_expression_up hsa-mir-146b Glioblastoma 30018734 The immune-related microRNA miR-146b is upregulated in glioblastoma recurrence. tissue_expression_up hsa-mir-21 Lung Neoplasms 30030592 Overview upon miR-21 in lung cancer: focus on NSCLC. tissue_expression_up hsa-mir-192 "Carcinoma, Ovarian" 30038317 The microRNA miR-192/215 family is upregulated in mucinous ovarian carcinomas. tissue_expression_up hsa-mir-215 "Carcinoma, Ovarian" 30038317 The microRNA miR-192/215 family is upregulated in mucinous ovarian carcinomas. tissue_expression_up hsa-mir-126 Cholangiocarcinoma 30042823 "High miR-126, low miR-128 and TEMs were independent prognostic factors for recurrence-free and overall survival" tissue_expression_up hsa-mir-515 "Carcinoma, Hepatocellular" 30052636 "HCC had significantly higher expression of members of the chromosome 19 miRNA cluster (C19MC), including miR-515-5p, miR-517a, miR-518b, and miR-520c-3p" tissue_expression_up hsa-mir-517a "Carcinoma, Hepatocellular" 30052636 "HCC had significantly higher expression of members of the chromosome 19 miRNA cluster (C19MC), including miR-515-5p, miR-517a, miR-518b, and miR-520c-3p" tissue_expression_up hsa-mir-518b "Carcinoma, Hepatocellular" 30052636 "HCC had significantly higher expression of members of the chromosome 19 miRNA cluster (C19MC), including miR-515-5p, miR-517a, miR-518b, and miR-520c-3p" tissue_expression_up hsa-mir-520c "Carcinoma, Hepatocellular" 30052636 "HCC had significantly higher expression of members of the chromosome 19 miRNA cluster (C19MC), including miR-515-5p, miR-517a, miR-518b, and miR-520c-3p" tissue_expression_up hsa-mir-372 "Adenocarcinoma, Lung" 30066858 "the predicted miRNA, miR-372-3p, exhibited a high expression in both the NSCLC and LUAD tissues" tissue_expression_up hsa-mir-372 "Carcinoma, Lung, Non-Small-Cell" 30066858 "the predicted miRNA, miR-372-3p, exhibited a high expression in both the NSCLC and LUAD tissues" tissue_expression_up hsa-mir-141 Neoplasms [unspecific] 30069274 Correlation between miR-200 Family Overexpression and Cancer Prognosis. tissue_expression_up hsa-mir-200a Neoplasms [unspecific] 30069274 Correlation between miR-200 Family Overexpression and Cancer Prognosis. tissue_expression_up hsa-mir-200b Neoplasms [unspecific] 30069274 Correlation between miR-200 Family Overexpression and Cancer Prognosis. tissue_expression_up hsa-mir-200c Neoplasms [unspecific] 30069274 Correlation between miR-200 Family Overexpression and Cancer Prognosis. tissue_expression_up hsa-mir-429 Neoplasms [unspecific] 30069274 Correlation between miR-200 Family Overexpression and Cancer Prognosis. tissue_expression_up hsa-mir-152 "Carcinoma, Adenoid Cystic" 30069755 "qPCR identified high expression of hsa-mir-21, hsa-mir-181a-2, and hsa-mir-152 to be associated with reduced OS and high expression of hsa-miR-374c to be associated with improved RFS" tissue_expression_up hsa-mir-181a "Carcinoma, Adenoid Cystic" 30069755 "qPCR identified high expression of hsa-mir-21, hsa-mir-181a-2, and hsa-mir-152 to be associated with reduced OS and high expression of hsa-miR-374c to be associated with improved RFS" tissue_expression_up hsa-mir-21 "Carcinoma, Adenoid Cystic" 30069755 "qPCR identified high expression of hsa-mir-21, hsa-mir-181a-2, and hsa-mir-152 to be associated with reduced OS and high expression of hsa-miR-374c to be associated with improved RFS" tissue_expression_up hsa-mir-374c "Carcinoma, Adenoid Cystic" 30069755 "qPCR identified high expression of hsa-mir-21, hsa-mir-181a-2, and hsa-mir-152 to be associated with reduced OS and high expression of hsa-miR-374c to be associated with improved RFS" tissue_expression_up hsa-mir-122 Liver Injury 30087537 "In liver injury, the levels of miR-122-5p, miR-192-5p, miR-223-3p, and miR-1224-5p were reported to be elevated in the sera" tissue_expression_up hsa-mir-1224 Liver Injury 30087537 "In liver injury, the levels of miR-122-5p, miR-192-5p, miR-223-3p, and miR-1224-5p were reported to be elevated in the sera" tissue_expression_up hsa-mir-192 Liver Injury 30087537 "In liver injury, the levels of miR-122-5p, miR-192-5p, miR-223-3p, and miR-1224-5p were reported to be elevated in the sera" tissue_expression_up hsa-mir-223 Liver Injury 30087537 "In liver injury, the levels of miR-122-5p, miR-192-5p, miR-223-3p, and miR-1224-5p were reported to be elevated in the sera" tissue_expression_up hsa-mir-112 Astrocytoma 30090984 "we found the upregulation of miR-210-3p, miR-155-5p, miR-UL-112-3p, miR-183-5p, and miR-223-5p in high-grade astrocytic tumors as compared with low-grade tumor tissues" tissue_expression_up hsa-mir-155 Astrocytoma 30090984 "we found the upregulation of miR-210-3p, miR-155-5p, miR-UL-112-3p, miR-183-5p, and miR-223-5p in high-grade astrocytic tumors as compared with low-grade tumor tissues" tissue_expression_up hsa-mir-183 Astrocytoma 30090984 "we found the upregulation of miR-210-3p, miR-155-5p, miR-UL-112-3p, miR-183-5p, and miR-223-5p in high-grade astrocytic tumors as compared with low-grade tumor tissues" tissue_expression_up hsa-mir-210 Astrocytoma 30090984 "we found the upregulation of miR-210-3p, miR-155-5p, miR-UL-112-3p, miR-183-5p, and miR-223-5p in high-grade astrocytic tumors as compared with low-grade tumor tissues" tissue_expression_up hsa-mir-223 Astrocytoma 30090984 "we found the upregulation of miR-210-3p, miR-155-5p, miR-UL-112-3p, miR-183-5p, and miR-223-5p in high-grade astrocytic tumors as compared with low-grade tumor tissues" tissue_expression_up hsa-mir-100 Ovarian Neoplasms 30107086 "We report that miR-21 (P?=?0.0001), miR-100 (P?=?0.034), miR-200b (P?=?0.008), and miR-320 (P?=?0.034) are significantly enriched, whereas miR-16 (P?=?0.009), miR-93 (P?=?0.014), miR-126 (P?=?0.012), and miR-223 (P?=?0.029) are underrepresented in exosomes from plasma of EOC patients as compared to those of healthy women. The levels of exosomal miR-23a (P?=?0.009, 0.008) and miR-92a (P?=?009, 0.034) were lower in ovarian cystadenoma patients than in EOC patients and healthy women, respectively" tissue_expression_up hsa-mir-200b Ovarian Neoplasms 30107086 "We report that miR-21 (P?=?0.0001), miR-100 (P?=?0.034), miR-200b (P?=?0.008), and miR-320 (P?=?0.034) are significantly enriched, whereas miR-16 (P?=?0.009), miR-93 (P?=?0.014), miR-126 (P?=?0.012), and miR-223 (P?=?0.029) are underrepresented in exosomes from plasma of EOC patients as compared to those of healthy women. The levels of exosomal miR-23a (P?=?0.009, 0.008) and miR-92a (P?=?009, 0.034) were lower in ovarian cystadenoma patients than in EOC patients and healthy women, respectively" tissue_expression_up hsa-mir-21 Ovarian Neoplasms 30107086 "We report that miR-21 (P?=?0.0001), miR-100 (P?=?0.034), miR-200b (P?=?0.008), and miR-320 (P?=?0.034) are significantly enriched, whereas miR-16 (P?=?0.009), miR-93 (P?=?0.014), miR-126 (P?=?0.012), and miR-223 (P?=?0.029) are underrepresented in exosomes from plasma of EOC patients as compared to those of healthy women. The levels of exosomal miR-23a (P?=?0.009, 0.008) and miR-92a (P?=?009, 0.034) were lower in ovarian cystadenoma patients than in EOC patients and healthy women, respectively" tissue_expression_up hsa-mir-320 Ovarian Neoplasms 30107086 "We report that miR-21 (P?=?0.0001), miR-100 (P?=?0.034), miR-200b (P?=?0.008), and miR-320 (P?=?0.034) are significantly enriched, whereas miR-16 (P?=?0.009), miR-93 (P?=?0.014), miR-126 (P?=?0.012), and miR-223 (P?=?0.029) are underrepresented in exosomes from plasma of EOC patients as compared to those of healthy women. The levels of exosomal miR-23a (P?=?0.009, 0.008) and miR-92a (P?=?009, 0.034) were lower in ovarian cystadenoma patients than in EOC patients and healthy women, respectively" tissue_expression_up hsa-mir-210 Prostate Neoplasms 30109809 The upregulation of hypoxia-related miRNA 210 in primary tumor of lymphogenic metastatic prostate cancer. tissue_expression_up hsa-mir-1 "Carcinoma, Lung, Non-Small-Cell" 30114862 "MiR-1, miR-124, and miR-196a are overexpressed in EGFR T790M mutated NSCLC" tissue_expression_up hsa-mir-124 "Carcinoma, Lung, Non-Small-Cell" 30114862 "MiR-1, miR-124, and miR-196a are overexpressed in EGFR T790M mutated NSCLC" tissue_expression_up hsa-mir-196a "Carcinoma, Lung, Non-Small-Cell" 30114862 "MiR-1, miR-124, and miR-196a are overexpressed in EGFR T790M mutated NSCLC" tissue_expression_up hsa-mir-195 Chronic Obstructive Pulmonary Disease 30115538 "FGFR1 was also a predicted target for some up-regulated miRNAs in COPD bronchial epithelial cells, including hsa-miR-195-5p, hsa-miR-424-5p, and hsa-miR-6724-5p" tissue_expression_up hsa-mir-424 Chronic Obstructive Pulmonary Disease 30115538 "FGFR1 was also a predicted target for some up-regulated miRNAs in COPD bronchial epithelial cells, including hsa-miR-195-5p, hsa-miR-424-5p, and hsa-miR-6724-5p" tissue_expression_up hsa-mir-6724 Chronic Obstructive Pulmonary Disease 30115538 "FGFR1 was also a predicted target for some up-regulated miRNAs in COPD bronchial epithelial cells, including hsa-miR-195-5p, hsa-miR-424-5p, and hsa-miR-6724-5p" tissue_expression_up hsa-mir-125a Colon Neoplasms 30127618 "seven miRNAs (hsa-miR-920, hsa-miR-636, hsa-miR-766-3p, hsa-miR-545-5p, hsa-miR-195-3p, hsa-miR-125a-3p, and hsa-miR-196b-3p) were found to be upregulated and six miRNAs (hsa-miR-3613-3p, hsa-miR-29b-3p, hsa-miR-1297, hsa-miR-141-5p, hsa-miR-200c-3p, and hsa-miR-141-3p) were found to be downregulated" tissue_expression_up hsa-mir-195 Colon Neoplasms 30127618 "seven miRNAs (hsa-miR-920, hsa-miR-636, hsa-miR-766-3p, hsa-miR-545-5p, hsa-miR-195-3p, hsa-miR-125a-3p, and hsa-miR-196b-3p) were found to be upregulated and six miRNAs (hsa-miR-3613-3p, hsa-miR-29b-3p, hsa-miR-1297, hsa-miR-141-5p, hsa-miR-200c-3p, and hsa-miR-141-3p) were found to be downregulated" tissue_expression_up hsa-mir-196b Colon Neoplasms 30127618 "seven miRNAs (hsa-miR-920, hsa-miR-636, hsa-miR-766-3p, hsa-miR-545-5p, hsa-miR-195-3p, hsa-miR-125a-3p, and hsa-miR-196b-3p) were found to be upregulated and six miRNAs (hsa-miR-3613-3p, hsa-miR-29b-3p, hsa-miR-1297, hsa-miR-141-5p, hsa-miR-200c-3p, and hsa-miR-141-3p) were found to be downregulated" tissue_expression_up hsa-mir-545 Colon Neoplasms 30127618 "seven miRNAs (hsa-miR-920, hsa-miR-636, hsa-miR-766-3p, hsa-miR-545-5p, hsa-miR-195-3p, hsa-miR-125a-3p, and hsa-miR-196b-3p) were found to be upregulated and six miRNAs (hsa-miR-3613-3p, hsa-miR-29b-3p, hsa-miR-1297, hsa-miR-141-5p, hsa-miR-200c-3p, and hsa-miR-141-3p) were found to be downregulated" tissue_expression_up hsa-mir-636 Colon Neoplasms 30127618 "seven miRNAs (hsa-miR-920, hsa-miR-636, hsa-miR-766-3p, hsa-miR-545-5p, hsa-miR-195-3p, hsa-miR-125a-3p, and hsa-miR-196b-3p) were found to be upregulated and six miRNAs (hsa-miR-3613-3p, hsa-miR-29b-3p, hsa-miR-1297, hsa-miR-141-5p, hsa-miR-200c-3p, and hsa-miR-141-3p) were found to be downregulated" tissue_expression_up hsa-mir-766 Colon Neoplasms 30127618 "seven miRNAs (hsa-miR-920, hsa-miR-636, hsa-miR-766-3p, hsa-miR-545-5p, hsa-miR-195-3p, hsa-miR-125a-3p, and hsa-miR-196b-3p) were found to be upregulated and six miRNAs (hsa-miR-3613-3p, hsa-miR-29b-3p, hsa-miR-1297, hsa-miR-141-5p, hsa-miR-200c-3p, and hsa-miR-141-3p) were found to be downregulated" tissue_expression_up hsa-mir-920 Colon Neoplasms 30127618 "seven miRNAs (hsa-miR-920, hsa-miR-636, hsa-miR-766-3p, hsa-miR-545-5p, hsa-miR-195-3p, hsa-miR-125a-3p, and hsa-miR-196b-3p) were found to be upregulated and six miRNAs (hsa-miR-3613-3p, hsa-miR-29b-3p, hsa-miR-1297, hsa-miR-141-5p, hsa-miR-200c-3p, and hsa-miR-141-3p) were found to be downregulated" tissue_expression_up hsa-mir-1225 Laryngeal Neoplasms 30138106 MicroRNA-1225-5p acts as a tumor-suppressor in laryngeal cancer via targeting CDC14B. tissue_expression_up hsa-mir-421 "Carcinoma, Lung, Non-Small-Cell" 30147363 Upregulated expression of miR-421 is associated with poor prognosis in non-small-cell lung cancer. tissue_expression_up hsa-mir-15b Uterine Leiomyoma 30149651 "The relative expression level of miR-15b was upregulated, and the relative expression levels of miR-29a, -29b, -29c, -197, and -200c were downregulated in UL cells compared to those in UM cells" tissue_expression_up hsa-mir-223 Amyotrophic Lateral Sclerosis 30154826 Wide-Ranging Analysis of MicroRNA Profiles in Sporadic Amyotrophic Lateral Sclerosis Using Next-Generation Sequencing. tissue_expression_up hsa-mir-336 Amyotrophic Lateral Sclerosis 30154826 Wide-Ranging Analysis of MicroRNA Profiles in Sporadic Amyotrophic Lateral Sclerosis Using Next-Generation Sequencing. tissue_expression_up hsa-mir-510 Fragile X Syndrome 30160796 High expression of miR-510 was associated with CGG expansion located at upstream of FMR1 into full mutation. tissue_expression_up hsa-mir-141 Cholangiocarcinoma 30165035 "the hsa-miR-205-5p and miR-200 family members were markedly up-regulated for 600-1500 folds, whereas the miR-199 family members and their clustered miRNA, hsa-miR-214-3p, were down-regulated for 1000-2000 folds" tissue_expression_up hsa-mir-200a Cholangiocarcinoma 30165035 "the hsa-miR-205-5p and miR-200 family members were markedly up-regulated for 600-1500 folds, whereas the miR-199 family members and their clustered miRNA, hsa-miR-214-3p, were down-regulated for 1000-2000 folds" tissue_expression_up hsa-mir-200b Cholangiocarcinoma 30165035 "the hsa-miR-205-5p and miR-200 family members were markedly up-regulated for 600-1500 folds, whereas the miR-199 family members and their clustered miRNA, hsa-miR-214-3p, were down-regulated for 1000-2000 folds" tissue_expression_up hsa-mir-200c Cholangiocarcinoma 30165035 "the hsa-miR-205-5p and miR-200 family members were markedly up-regulated for 600-1500 folds, whereas the miR-199 family members and their clustered miRNA, hsa-miR-214-3p, were down-regulated for 1000-2000 folds" tissue_expression_up hsa-mir-205 Cholangiocarcinoma 30165035 "the hsa-miR-205-5p and miR-200 family members were markedly up-regulated for 600-1500 folds, whereas the miR-199 family members and their clustered miRNA, hsa-miR-214-3p, were down-regulated for 1000-2000 folds" tissue_expression_up hsa-mir-429 Cholangiocarcinoma 30165035 "the hsa-miR-205-5p and miR-200 family members were markedly up-regulated for 600-1500 folds, whereas the miR-199 family members and their clustered miRNA, hsa-miR-214-3p, were down-regulated for 1000-2000 folds" tissue_expression_up hsa-let-7i Traumatic Brain Injury 30177873 "no significant variations of the 65 inflammatory proteins detected in saliva between groups but 5 microRNAs, miR-27b-3p (p = 0.016), let-7i-5p (p = 0.001), miR-142-3p(p = 0.008), miR-107 (p = 0.028), miR-135b-5p (p = 0.017) significantly upregulated in concussed athletes" tissue_expression_up hsa-mir-107 Traumatic Brain Injury 30177873 "no significant variations of the 65 inflammatory proteins detected in saliva between groups but 5 microRNAs, miR-27b-3p (p = 0.016), let-7i-5p (p = 0.001), miR-142-3p(p = 0.008), miR-107 (p = 0.028), miR-135b-5p (p = 0.017) significantly upregulated in concussed athletes" tissue_expression_up hsa-mir-135b Traumatic Brain Injury 30177873 "no significant variations of the 65 inflammatory proteins detected in saliva between groups but 5 microRNAs, miR-27b-3p (p = 0.016), let-7i-5p (p = 0.001), miR-142-3p(p = 0.008), miR-107 (p = 0.028), miR-135b-5p (p = 0.017) significantly upregulated in concussed athletes" tissue_expression_up hsa-mir-142 Traumatic Brain Injury 30177873 "no significant variations of the 65 inflammatory proteins detected in saliva between groups but 5 microRNAs, miR-27b-3p (p = 0.016), let-7i-5p (p = 0.001), miR-142-3p(p = 0.008), miR-107 (p = 0.028), miR-135b-5p (p = 0.017) significantly upregulated in concussed athletes" tissue_expression_up hsa-mir-27b Traumatic Brain Injury 30177873 "no significant variations of the 65 inflammatory proteins detected in saliva between groups but 5 microRNAs, miR-27b-3p (p = 0.016), let-7i-5p (p = 0.001), miR-142-3p(p = 0.008), miR-107 (p = 0.028), miR-135b-5p (p = 0.017) significantly upregulated in concussed athletes" tissue_expression_up hsa-let-7f Irritable Bowel Syndrome 30187701 MiRNAs play a pivotal role in visceral hypersensitivity and might be targets in the treatment of IBS by Tongxieyaofang tissue_expression_up hsa-let-7i Irritable Bowel Syndrome 30187701 MiRNAs play a pivotal role in visceral hypersensitivity and might be targets in the treatment of IBS by Tongxieyaofang tissue_expression_up hsa-mir-130b Irritable Bowel Syndrome 30187701 MiRNAs play a pivotal role in visceral hypersensitivity and might be targets in the treatment of IBS by Tongxieyaofang tissue_expression_up hsa-mir-132 Irritable Bowel Syndrome 30187701 MiRNAs play a pivotal role in visceral hypersensitivity and might be targets in the treatment of IBS by Tongxieyaofang tissue_expression_up hsa-mir-21 Irritable Bowel Syndrome 30187701 MiRNAs play a pivotal role in visceral hypersensitivity and might be targets in the treatment of IBS by Tongxieyaofang tissue_expression_up hsa-mir-29a Irritable Bowel Syndrome 30187701 MiRNAs play a pivotal role in visceral hypersensitivity and might be targets in the treatment of IBS by Tongxieyaofang tissue_expression_up hsa-mir-375 Irritable Bowel Syndrome 30187701 MiRNAs play a pivotal role in visceral hypersensitivity and might be targets in the treatment of IBS by Tongxieyaofang tissue_expression_up hsa-let-7b Endometrial Stromal Sarcoma 30200635 "In endometrial stromal sarcomas (ESS), the upregulation of miR-373-3p, miR-372-3p, and let-7b-5p, and the down-expression of let-7f-5p, miR-23-3p, and let-7b-5p were associated with lower CSS" tissue_expression_up hsa-mir-184 Carcinosarcoma 30200635 "In carcinosarcoma (CS), lower CSS was associated with the upregulation of miR-184, and the downregulation of let-7b-5p and miR-124" tissue_expression_up hsa-mir-196a Leiomyosarcoma 30200635 "In leiomyosarcoma (LMS), there was an association of lower cancer-specific survival (CSS) with the downregulation of miR-125a-5p and miR-10a-5p, and the upregulation of miR-196a-5p and miR-34c-5p" tissue_expression_up hsa-mir-34c Leiomyosarcoma 30200635 "In leiomyosarcoma (LMS), there was an association of lower cancer-specific survival (CSS) with the downregulation of miR-125a-5p and miR-10a-5p, and the upregulation of miR-196a-5p and miR-34c-5p" tissue_expression_up hsa-mir-372 Endometrial Stromal Sarcoma 30200635 "In endometrial stromal sarcomas (ESS), the upregulation of miR-373-3p, miR-372-3p, and let-7b-5p, and the down-expression of let-7f-5p, miR-23-3p, and let-7b-5p were associated with lower CSS" tissue_expression_up hsa-mir-373 Endometrial Stromal Sarcoma 30200635 "In endometrial stromal sarcomas (ESS), the upregulation of miR-373-3p, miR-372-3p, and let-7b-5p, and the down-expression of let-7f-5p, miR-23-3p, and let-7b-5p were associated with lower CSS" tissue_expression_up hsa-mir-450b "Squamous Cell Carcinoma, Oral" 30210912 "The expression levels of miR-129-5p and miR-296-5p were significantly downregulated in OLK-OSCC tissues compared to OLK tissues, while miR-450b-5p levels were higher in OLK-OSCC tissues" tissue_expression_up hsa-mir-141 "Carcinoma, Cervical" 30221475 "The expression levels of six miRNAs (miR-20a, miR-92a, miR-141, miR-183*, miR-210 and miR-944) were found to be significantly up-regulated in cervical cancer" tissue_expression_up hsa-mir-183 "Carcinoma, Cervical" 30221475 "The expression levels of six miRNAs (miR-20a, miR-92a, miR-141, miR-183*, miR-210 and miR-944) were found to be significantly up-regulated in cervical cancer" tissue_expression_up hsa-mir-20a "Carcinoma, Cervical" 30221475 "The expression levels of six miRNAs (miR-20a, miR-92a, miR-141, miR-183*, miR-210 and miR-944) were found to be significantly up-regulated in cervical cancer" tissue_expression_up hsa-mir-210 "Carcinoma, Cervical" 30221475 "The expression levels of six miRNAs (miR-20a, miR-92a, miR-141, miR-183*, miR-210 and miR-944) were found to be significantly up-regulated in cervical cancer" tissue_expression_up hsa-mir-92a "Carcinoma, Cervical" 30221475 "The expression levels of six miRNAs (miR-20a, miR-92a, miR-141, miR-183*, miR-210 and miR-944) were found to be significantly up-regulated in cervical cancer" tissue_expression_up hsa-mir-944 "Carcinoma, Cervical" 30221475 "The expression levels of six miRNAs (miR-20a, miR-92a, miR-141, miR-183*, miR-210 and miR-944) were found to be significantly up-regulated in cervical cancer" tissue_expression_up hsa-mir-139 Neoplasms [unspecific] 30225717 "Bioinformatic analysis has detected microRNA potentially regulated by xenosensor receptors AhR (miR-28, miR-30c, miR-30e, miR-139, and miR-153) and CAR (miR-29c, miR-31, miR-185, miR-625, and miR-652)" tissue_expression_up hsa-mir-153 Neoplasms [unspecific] 30225717 "Bioinformatic analysis has detected microRNA potentially regulated by xenosensor receptors AhR (miR-28, miR-30c, miR-30e, miR-139, and miR-153) and CAR (miR-29c, miR-31, miR-185, miR-625, and miR-652)" tissue_expression_up hsa-mir-185 Neoplasms [unspecific] 30225717 "Bioinformatic analysis has detected microRNA potentially regulated by xenosensor receptors AhR (miR-28, miR-30c, miR-30e, miR-139, and miR-153) and CAR (miR-29c, miR-31, miR-185, miR-625, and miR-652)" tissue_expression_up hsa-mir-28 Neoplasms [unspecific] 30225717 "Bioinformatic analysis has detected microRNA potentially regulated by xenosensor receptors AhR (miR-28, miR-30c, miR-30e, miR-139, and miR-153) and CAR (miR-29c, miR-31, miR-185, miR-625, and miR-652)" tissue_expression_up hsa-mir-29c Neoplasms [unspecific] 30225717 "Bioinformatic analysis has detected microRNA potentially regulated by xenosensor receptors AhR (miR-28, miR-30c, miR-30e, miR-139, and miR-153) and CAR (miR-29c, miR-31, miR-185, miR-625, and miR-652)" tissue_expression_up hsa-mir-30c Neoplasms [unspecific] 30225717 "Bioinformatic analysis has detected microRNA potentially regulated by xenosensor receptors AhR (miR-28, miR-30c, miR-30e, miR-139, and miR-153) and CAR (miR-29c, miR-31, miR-185, miR-625, and miR-652)" tissue_expression_up hsa-mir-30e Neoplasms [unspecific] 30225717 "Bioinformatic analysis has detected microRNA potentially regulated by xenosensor receptors AhR (miR-28, miR-30c, miR-30e, miR-139, and miR-153) and CAR (miR-29c, miR-31, miR-185, miR-625, and miR-652)" tissue_expression_up hsa-mir-31 Neoplasms [unspecific] 30225717 "Bioinformatic analysis has detected microRNA potentially regulated by xenosensor receptors AhR (miR-28, miR-30c, miR-30e, miR-139, and miR-153) and CAR (miR-29c, miR-31, miR-185, miR-625, and miR-652)" tissue_expression_up hsa-mir-625 Neoplasms [unspecific] 30225717 "Bioinformatic analysis has detected microRNA potentially regulated by xenosensor receptors AhR (miR-28, miR-30c, miR-30e, miR-139, and miR-153) and CAR (miR-29c, miR-31, miR-185, miR-625, and miR-652)" tissue_expression_up hsa-mir-183 Endometrial Neoplasms 30226564 "Upregulation of miR-183-5p is responsible for the promotion of apoptosis and inhibition of the epithelial-mesenchymal transition, proliferation, invasion and migration of human endometrial cancer cells by downregulating Ezrin." tissue_expression_up hsa-mir-3195 Traumatic Brain Injury 30226895 The expression levels of miR-3195 and miR-328-5p were higher in the severe TBI group than in the mild and moderate TBI groups tissue_expression_up hsa-mir-328 Traumatic Brain Injury 30226895 The expression levels of miR-3195 and miR-328-5p were higher in the severe TBI group than in the mild and moderate TBI groups tissue_expression_up hsa-mir-486 Colorectal Carcinoma 30239392 MiR-486-5p Downregulation Marks an Early Event in Colorectal Carcinogenesis. tissue_expression_up hsa-mir-211 Medulloblastoma 30244244 "Ligustrazine Inhibits Growth, Migration and Invasion of Medulloblastoma Daoy Cells by Up-Regulation of miR-211." tissue_expression_up hsa-mir-155 "Carcinoma, Breast" 30250531 3 miRNAs were upregulated: Hsa-miR-21b; hsa-miR-29b; and hsa-miR-155; and 3 miRNAs were downregulated: Hsa-miR-10b; hsa-miR-125; and hsa-miR-145 tissue_expression_up hsa-mir-21b "Carcinoma, Breast" 30250531 3 miRNAs were upregulated: Hsa-miR-21b; hsa-miR-29b; and hsa-miR-155; and 3 miRNAs were downregulated: Hsa-miR-10b; hsa-miR-125; and hsa-miR-145 tissue_expression_up hsa-mir-29b "Carcinoma, Breast" 30250531 3 miRNAs were upregulated: Hsa-miR-21b; hsa-miR-29b; and hsa-miR-155; and 3 miRNAs were downregulated: Hsa-miR-10b; hsa-miR-125; and hsa-miR-145 tissue_expression_up hsa-mir-484 "Carcinoma, Hepatocellular" 30254459 the expression of miR-10a-5p is downregulated and miR-484 is the most abundant miRNA in hepatic precancerous lesions tissue_expression_up hsa-mir-107 Gastric Neoplasms 30258124 "Six miRNA (miR-601, miR-107, miR-18a, miR-370, miR-300, and miR-96) showed increased expression in gastric cancer compared to normal or adenoma samples" tissue_expression_up hsa-mir-18a Gastric Neoplasms 30258124 "Six miRNA (miR-601, miR-107, miR-18a, miR-370, miR-300, and miR-96) showed increased expression in gastric cancer compared to normal or adenoma samples" tissue_expression_up hsa-mir-300 Gastric Neoplasms 30258124 "Six miRNA (miR-601, miR-107, miR-18a, miR-370, miR-300, and miR-96) showed increased expression in gastric cancer compared to normal or adenoma samples" tissue_expression_up hsa-mir-370 Gastric Neoplasms 30258124 "Six miRNA (miR-601, miR-107, miR-18a, miR-370, miR-300, and miR-96) showed increased expression in gastric cancer compared to normal or adenoma samples" tissue_expression_up hsa-mir-601 Gastric Neoplasms 30258124 "Six miRNA (miR-601, miR-107, miR-18a, miR-370, miR-300, and miR-96) showed increased expression in gastric cancer compared to normal or adenoma samples" tissue_expression_up hsa-mir-96 Gastric Neoplasms 30258124 "Six miRNA (miR-601, miR-107, miR-18a, miR-370, miR-300, and miR-96) showed increased expression in gastric cancer compared to normal or adenoma samples" tissue_expression_up hsa-mir-29c Acute Liver Failure 30264499 Comparison of microRNA expressions for the identification of chemical hazards in in vivo and in vitro hepatic injury models. tissue_expression_up hsa-mir-26b "Carcinoma, Hepatocellular" 30309482 Lentiviral-mediated microRNA-26b up-regulation inhibits proliferation and migration of hepatocellular carcinoma cells. tissue_expression_up hsa-mir-21 Ischemia-Reperfusion Injury 30309483 MicroRNA-21 is upregulated during intestinal barrier dysfunction induced by ischemia reperfusion. tissue_expression_up hsa-mir-193a "Carcinoma, Pancreatic" 30333874 "The results revealed that 2 upregulated miRNAs (miR-34a and -193a-3p) and 4 downregulated miRNAs (miR-221, -222, -484, and -502-3p) exhibited a consistent expression pattern between the PC-1.0/PC-1 and AsPC-1/CAPAN-2 pancreatic cancer cells" tissue_expression_up hsa-mir-34a "Carcinoma, Pancreatic" 30333874 "The results revealed that 2 upregulated miRNAs (miR-34a and -193a-3p) and 4 downregulated miRNAs (miR-221, -222, -484, and -502-3p) exhibited a consistent expression pattern between the PC-1.0/PC-1 and AsPC-1/CAPAN-2 pancreatic cancer cells" tissue_expression_up hsa-mir-155 "Carcinoma, Renal Cell" 30344735 "2 upregulated (hsa-miR-155-5p and hsa-miR-210-5p) and 6 downregulated (hsa-miR-138-5p, hsa-miR-141-5p, hsa-miR-200c-5p, hsa-miR-362-5p, hsa-miR-363-5p and hsa-miR-429) meta-signature miRNAs in renal carcinoma were identified" tissue_expression_up hsa-mir-210 "Carcinoma, Renal Cell" 30344735 "2 upregulated (hsa-miR-155-5p and hsa-miR-210-5p) and 6 downregulated (hsa-miR-138-5p, hsa-miR-141-5p, hsa-miR-200c-5p, hsa-miR-362-5p, hsa-miR-363-5p and hsa-miR-429) meta-signature miRNAs in renal carcinoma were identified" tissue_expression_up hsa-let-7b Periodontitis 30350903 "the most expressed miRNAs in both groups were hsa-miR-1274b, hsa-let-7b-5p, hsa-miR-24-3p, hsa-miR-19b-3p, hsa-miR-720, hsa-miR-126-3p, hsa-miR-17-3p and hsa-miR-21-3p." tissue_expression_up hsa-mir-126 Periodontitis 30350903 "the most expressed miRNAs in both groups were hsa-miR-1274b, hsa-let-7b-5p, hsa-miR-24-3p, hsa-miR-19b-3p, hsa-miR-720, hsa-miR-126-3p, hsa-miR-17-3p and hsa-miR-21-3p." tissue_expression_up hsa-mir-1274b Periodontitis 30350903 "the most expressed miRNAs in both groups were hsa-miR-1274b, hsa-let-7b-5p, hsa-miR-24-3p, hsa-miR-19b-3p, hsa-miR-720, hsa-miR-126-3p, hsa-miR-17-3p and hsa-miR-21-3p." tissue_expression_up hsa-mir-17 Periodontitis 30350903 "the most expressed miRNAs in both groups were hsa-miR-1274b, hsa-let-7b-5p, hsa-miR-24-3p, hsa-miR-19b-3p, hsa-miR-720, hsa-miR-126-3p, hsa-miR-17-3p and hsa-miR-21-3p." tissue_expression_up hsa-mir-19b Periodontitis 30350903 "the most expressed miRNAs in both groups were hsa-miR-1274b, hsa-let-7b-5p, hsa-miR-24-3p, hsa-miR-19b-3p, hsa-miR-720, hsa-miR-126-3p, hsa-miR-17-3p and hsa-miR-21-3p." tissue_expression_up hsa-mir-21 Periodontitis 30350903 "the most expressed miRNAs in both groups were hsa-miR-1274b, hsa-let-7b-5p, hsa-miR-24-3p, hsa-miR-19b-3p, hsa-miR-720, hsa-miR-126-3p, hsa-miR-17-3p and hsa-miR-21-3p." tissue_expression_up hsa-mir-24 Periodontitis 30350903 "the most expressed miRNAs in both groups were hsa-miR-1274b, hsa-let-7b-5p, hsa-miR-24-3p, hsa-miR-19b-3p, hsa-miR-720, hsa-miR-126-3p, hsa-miR-17-3p and hsa-miR-21-3p." tissue_expression_up hsa-mir-720 Periodontitis 30350903 "the most expressed miRNAs in both groups were hsa-miR-1274b, hsa-let-7b-5p, hsa-miR-24-3p, hsa-miR-19b-3p, hsa-miR-720, hsa-miR-126-3p, hsa-miR-17-3p and hsa-miR-21-3p." tissue_expression_up hsa-mir-1283 Parkinson Disease 30359694 "all three FTY720s increased miR376b-3p, while FTY720-C2 also increased miR-128-3p, miR-146b-5p, miR-7a-5p, and miR-9-5p, and FTY720-Mitoxy also increased miR-30d-5p" tissue_expression_up hsa-mir-146b Parkinson Disease 30359694 "all three FTY720s increased miR376b-3p, while FTY720-C2 also increased miR-128-3p, miR-146b-5p, miR-7a-5p, and miR-9-5p, and FTY720-Mitoxy also increased miR-30d-5p" tissue_expression_up hsa-mir-30d Parkinson Disease 30359694 "all three FTY720s increased miR376b-3p, while FTY720-C2 also increased miR-128-3p, miR-146b-5p, miR-7a-5p, and miR-9-5p, and FTY720-Mitoxy also increased miR-30d-5p" tissue_expression_up hsa-mir-376b Parkinson Disease 30359694 "all three FTY720s increased miR376b-3p, while FTY720-C2 also increased miR-128-3p, miR-146b-5p, miR-7a-5p, and miR-9-5p, and FTY720-Mitoxy also increased miR-30d-5p" tissue_expression_up hsa-mir-7a Parkinson Disease 30359694 "all three FTY720s increased miR376b-3p, while FTY720-C2 also increased miR-128-3p, miR-146b-5p, miR-7a-5p, and miR-9-5p, and FTY720-Mitoxy also increased miR-30d-5p" tissue_expression_up hsa-mir-9 Parkinson Disease 30359694 "all three FTY720s increased miR376b-3p, while FTY720-C2 also increased miR-128-3p, miR-146b-5p, miR-7a-5p, and miR-9-5p, and FTY720-Mitoxy also increased miR-30d-5p" tissue_expression_up hsa-mir-210 Rhinosinusitis 30378273 "Five upregulated miRNAs, including miR-210-5p, miR-3178, miR-585-3p, miR-3146, and miR-320e, and 19 downregulated miRNAs, including miR-32-3p, miR-1299, miR-3196, miR-3924, and miR-548e-3p, were differentially expressed (p < 0.05, fold change >2) in tissues of CRSwNP vs controls" tissue_expression_up hsa-mir-3146 Rhinosinusitis 30378273 "Five upregulated miRNAs, including miR-210-5p, miR-3178, miR-585-3p, miR-3146, and miR-320e, and 19 downregulated miRNAs, including miR-32-3p, miR-1299, miR-3196, miR-3924, and miR-548e-3p, were differentially expressed (p < 0.05, fold change >2) in tissues of CRSwNP vs controls" tissue_expression_up hsa-mir-3178 Rhinosinusitis 30378273 "Five upregulated miRNAs, including miR-210-5p, miR-3178, miR-585-3p, miR-3146, and miR-320e, and 19 downregulated miRNAs, including miR-32-3p, miR-1299, miR-3196, miR-3924, and miR-548e-3p, were differentially expressed (p < 0.05, fold change >2) in tissues of CRSwNP vs controls" tissue_expression_up hsa-mir-320e Rhinosinusitis 30378273 "Five upregulated miRNAs, including miR-210-5p, miR-3178, miR-585-3p, miR-3146, and miR-320e, and 19 downregulated miRNAs, including miR-32-3p, miR-1299, miR-3196, miR-3924, and miR-548e-3p, were differentially expressed (p < 0.05, fold change >2) in tissues of CRSwNP vs controls" tissue_expression_up hsa-mir-585 Rhinosinusitis 30378273 "Five upregulated miRNAs, including miR-210-5p, miR-3178, miR-585-3p, miR-3146, and miR-320e, and 19 downregulated miRNAs, including miR-32-3p, miR-1299, miR-3196, miR-3924, and miR-548e-3p, were differentially expressed (p < 0.05, fold change >2) in tissues of CRSwNP vs controls" tissue_expression_up hsa-mir-1269a Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis.(up) tissue_expression_up hsa-mir-183 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis.(up) tissue_expression_up hsa-mir-210 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis.(up) tissue_expression_up hsa-mir-301b Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis.(up) tissue_expression_up hsa-mir-3648 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis.(up) tissue_expression_up hsa-mir-3687 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis.(up) tissue_expression_up hsa-mir-4746 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis.(up) tissue_expression_up hsa-mir-760 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis.(up) tissue_expression_up hsa-mir-96 Neoplasms [unspecific] 30384176 Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis.(up)