miRNA name: hsa-mir-151a Category Disease_belong Disease_name PMID DOID ICD10CM MESH OMIM HPO GO Description Causality other psoriasis 1 31465725 DOID:0111286 177900 Of 36 common expressed microRNAs, 5 microRNAs, including hsa-miR-151a-3p, hsa-miR-199a-5p, hsa-miR3p, hsa-miR5p, and hsa-miR5p, were considered to be connected with the common pathogenesis of PsA, PV, RA, and GA. Unknown other Alzheimer Disease 36685889 DOID:10652 G30 D000544 Results: Quantitative miRNA PCR assays showed that hsa-let-7a-5p, hsa-let-7days-3p, hsa-let-7e-5p, and hsa-miR-151a-5p were significantly up-regulated in both AD-ACD (+) and AD-ACD (-) as were hsa-miR-130a-3p, hsa-miR-151a-3p, has-miR-27b-3p, and hsa-miR-146a-5p in AD-ACD (+) but not in AD-ACD (-) . Unknown other Carcinoma, Non-Small-Cell Lung 32577162 DOID:3908 D002289 We have previously established that miR-151a functions as an onco-miR in non-small cell lung cancer (NSCLC) cells by inducing partial EMT and enhancing tumor growth. Finally, we verify that miR-151a is expressed in the vasculature of normal lung and NSCLC tissue. Unknown other Corneal dystrophy, epithelial basement membrane 31832755 DOID:0060447 H18.5 C535477 121820 Especially, miR-151a and miR-186 were more abundant in BM and GCB than in GCF and GJ. Our study is the first to elucidate the human GJ miRNA profile and demonstrate the possibility that miR-151a and miR-186 in GC may be the biomarker of breast-feeding. Unknown other Blood Platelet Disorders 32806499 DOID:2218 D001791 Our results identified a new collection of miRNAs (miR5p, miR-92a-3p, miR-103a-3p, miR-151a-3p, miR-181a-5p, and miR3p) that showed a sensitivity expression pattern due to biological platelet changes during storage, confirmed by additional quantitative real-time polymerase chain reaction (qPCR) validation on 100 PC units from 500 healthy donors. Unknown other Colorectal Neoplasms 36704851 DOID:0080199 D015179 Taken together, the results of the current study revealed a novel molecular mechanism indicating that the miR151a5p/AGMAT axis could serve a crucial role in the regulation of CRC and could therefore be considered as a potential therapeutic strategy for CRC. Unknown other Atrial Fibrillation 35513595 DOID:0060224 D001281 We also found that miR5p was up-regulated in POAF patients, but there are no significant changes in miR5p, miR-181a-5p, miR5p and miR-151a-5p. Unknown circulation_biomarker_diagnosis_ns Parkinson Disease 34315539 DOID:14330 G20 D010300 PS168600 CONCLUSIONS: The 6 serum EV-derived miRNAs, hsa-miR-374a-5p, hsa-miR-374b-5p, hsa-miR-199a-3p, hsa-miR5p, hsa-miR5p and hsa-miR-151a-5p, may potentially be used as biomarkers for PD progression and for early diagnosis of PD in populations. Unknown circulation_biomarker_diagnosis_ns Heart Neoplasms 33713567 DOID:117 C38.0 D006338 We found three miRNAs with significantly increased serum levels in patients with biopsy-proven cardiac rejection when compared with patients without rejection: hsa-miR5p, hsa-miR-151a-5p, and hsa-miR5p. Unknown other Asthenozoospermia 31749176 D053627 The present study demonstrated that hsa-miR-27b-3p, hsa-miR-151a-5p and hsa-miR-206 play an important role in the effects of l-carnitine treatment of the spermatozoa in asthenospermia patients. Unknown other Delayed Graft Function 31309102 D051799 Three coexpressed miRNAs, hsa-miR-33a-5p_R-1, hsa-miR5p, and hsa-miR-151a-5p, were observed to be significantly upregulated in kidney recipients with DGF. Unknown other Leukemia, Biphenotypic, Acute 30393877 DOID:9953 C95.0 D015456 Sixteen miRNAs were differentially expressed between T- and B-ALL, of which 10 (miR5p, miR5p, miR-151a-5p, miR-151b, miR-371b-5p, miR5p, miR5p, miR5p, miR5p, and miR5p) were downregulated and six (miR-450b-5p, miR-450a-5p, miR5p, miR5p, miR5p, and miR-29c-5p) were upregulated in childhood T-ALL. Unknown circulation_biomarker_diagnosis_ns Parkinson Disease 35432916 DOID:14330 G20 D010300 PS168600 CONCLUSIONS: The significant level of miR-151a-5p, miR-24, mir5p, mir5p, and mir-214 was observed in the serum and CSF which may be established as a biomarker for the diagnosis of PD. Unknown circulation_biomarker_diagnosis_up Amyotrophic Lateral Sclerosis 33431881 DOID:332 G12.21 D000690 PS105400 In particular, we found that miR-206 and miR-151a-5p serum levels were significantly up-regulated at the mild stage of ALS pathology, to decrease in the following moderate and severe stages, whereas the expression levels of miR-133a and miR-199a-5p remained low throughout the course of the disease, showing a diagnostic significance in moderate and severe stages for miR-133a and in mild and terminal ones for miR-199a-5p. Unknown other Thyroid Nodule 32765676 D016606 The expression levels of miRNA146b, miRNA187, miRNA375, miRNA3p and miRNA-151a-5p were higher, while the level of miRNA138 was lower, in patients with either benign or malignant thyroid nodules compaed to those in the control group. The expression levels of miRNA146b, miRNA187, miRNA375, miRNA3p and miRNA-151a-5p were higher, while the level of miRNA138 was lower, in patients with malignant thyroid nodules than those in patients with benign thyroid nodule (P<0.05). Unknown other Prader-Willi Syndrome 32295264 DOID:11983 Q87.11 D011218 176270 When stratifying groups according to the presence of steatosis, the expression of miR-151a-5p, miR-92a-3p, miR-106b-5p, and miR5p were lower in PWS with steatosis grade 1. Within the group with steatosis grade 1, miR-151a-5p was significantly distinguished PWS from obese (AUC = 0.85, sens/spec 80/85%) and the combination of miR-106b-5p and miR5p showed higher performances in discriminating different grades of steatosis in PWS (AUC = 0.84, sens/spec 93/74%). Unknown other Fatty Liver 32295264 DOID:9452 K70.0 D005234 228100 When stratifying groups according to the presence of steatosis, the expression of miR-151a-5p, miR-92a-3p, miR-106b-5p, and miR5p were lower in PWS with steatosis grade 1. Within the group with steatosis grade 1, miR-151a-5p was significantly distinguished PWS from obese (AUC = 0.85, sens/spec 80/85%) and the combination of miR-106b-5p and miR5p showed higher performances in discriminating different grades of steatosis in PWS (AUC = 0.84, sens/spec 93/74%). Unknown other Neurodevelopmental Disorders 36674994 D065886 This pilot study provides evidence that miR-151a-3p may aid the identification of infants at risk for neurodevelopmental delay. Unknown other Breast Neoplasms 36232660 DOID:1612 C50 D001943 114480 Two of the most significantly upregulated microRNAs, miR-199a-3p and miR-151a-3p, were strongly correlated with the onset of lymphedema and diabetes mellitus in the BCRL group. Unknown circulation_biomarker_prognosis_up Stomach Neoplasms 34535770 DOID:10534 C16 D013274 613659 sEV-miR-151a-3p could be a promising diagnostic biomarker and preventive treatment candidate for GC-LM. Unknown circulation_biomarker_diagnosis_up Osteoporosis, Postmenopausal 34290498 D015663 CONCLUSION: MicroRNA-151a-3p could partly regulate osteoporosis by promoting osteoclast differentiation, and miRNA-151a-3p could be a potential therapeutic target for postmenopausal osteoporosis. Unknown other Non-alcoholic Fatty Liver Disease 34282172 DOID:0080208 D065626 613282 Only four miRNAs (miR5p, miR-151a-3p, miR5p, and miR-4449) showed significant area under the receiver operating characteristic curve (AUC) values for NASH diagnosis. Unknown other Coronary Artery Disease 33866193 DOID:3393 I20-I25 D003324 300464 FINDINGS: From 15 differentially expressed miRNAs detected in cohort 1, we confirmed in cohort 2 the differential expression of 4 miRNAs: miR-let-7f-5p, miR-146a-5p, miR-151a-3p and miR5p, whose expression was higher in SCAD compared to AT-AMI. miR-let-7f-5p, miR-146a-5p, miR-151a-3p and miR5p discriminate SCAD from AT-AMI patients and also shed light on the pathological mechanisms underlying this condition. Unknown other Ischemic Stroke 33818699 D000083242 CONCLUSIONS: miRNAs were involved in IS pathogenesis, and hsa-miR5p, hsa-miR-151a-3p and hsa-miR-29c-5p as the three highest |log2FoldChange| regulation in this study, which may be the biomarkers of IS and need further study. Unknown other Myelodysplastic Syndromes 32629683 DOID:0050908 D009190 614286 RESULTS: MiRNA microarray analysis showed 96 significantly upregulated (eg, miR-146a-5p, miR-151a-3p, miR-125b-5p) and 198 significantly downregulated (eg, miR-181a3p, miR3p, miR-550a-3p) microRNAs in MDS compared with normal bone marrow. The quantitative real-time polymerase chain reaction confirmed the microarray analysis: expression of six microRNAs (miR5p, miR-146a-5p, miR-151a-3p, miR3p, miR-125b-5p, and miR-10a-5p) was significantly higher in MDS, while 3 microRNAs (miR-181a3p, miR3p, and miR-550a-3p) were significantly downregulated in MDS. Unknown circulation_biomarker_diagnosis_up Uterine Cervical Neoplasms 31658043 DOID:4362 C53 D002583 603956 RESULTS: Four plasma miRNAs (miR-146a-5p, miR-151a-3p, miR-2110 and miR5p) which showed up-regulation were identified and validated in CC patients. miR-146a-5p and miR5p levels were all up-regulated in CC tissue specimens, whereas miR-146a-5p, miR-151a-3p, and miR-2110 levels were up-regulated in plasma exosomes. Unknown other Tuberculosis, Meningeal 31572691 D014390 Statistically significant differences of 4 miRNAs (miR3p, miR-130a-3p, miR-151a-3p, and miR-199a-5p) were further confirmed in TBM compared with VM and HCs in independent PBMCs sample set (n = 96, P < 0.01). Unknown other Uterine Cervical Neoplasms 31498525 DOID:4362 C53 D002583 603956 RESULTS: We identified three up-regulated miRNAs (hsa-miR-1291, hsa-miR5p and hsa-miR-5701) and seven down-regulated known-miRNAs (hsa-miR5p, hsa-miR3p, hsa-miR3p, hsa-miR-151a-3p, hsa-miR3p, hsa-miR-199a-3p and hsa-miR-199b-3p) relative to HPV16Neg. Unknown other Arthritis, Gouty 31465725 D015210 Of 36 common expressed microRNAs, 5 microRNAs, including hsa-miR-151a-3p, hsa-miR-199a-5p, hsa-miR3p, hsa-miR5p, and hsa-miR5p, were considered to be connected with the common pathogenesis of PsA, PV, RA, and GA. Unknown other Arthritis, Rheumatoid 31465725 DOID:7148 M06.9 D001172 180300 Of 36 common expressed microRNAs, 5 microRNAs, including hsa-miR-151a-3p, hsa-miR-199a-5p, hsa-miR3p, hsa-miR5p, and hsa-miR5p, were considered to be connected with the common pathogenesis of PsA, PV, RA, and GA. Unknown other Arthritis, Psoriatic 31465725 DOID:9008 L40.5 D015535 Of 36 common expressed microRNAs, 5 microRNAs, including hsa-miR-151a-3p, hsa-miR-199a-5p, hsa-miR3p, hsa-miR5p, and hsa-miR5p, were considered to be connected with the common pathogenesis of PsA, PV, RA, and GA. Unknown other Teratoma 31353396 DOID:3307 D013724 Comparisons of cancer and mature teratoma identified two markedly upregulated miRNAs (miR-151a-3p and miR-378a-3p) and two markedly downregulated miRNAs (miR-26a-5p and miR-99a-5p). Unknown other Carcinoma, Squamous Cell 31353396 DOID:1749 D002294 Comparisons of cancer and mature teratoma identified two markedly upregulated miRNAs (miR-151a-3p and miR-378a-3p) and two markedly downregulated miRNAs (miR-26a-5p and miR-99a-5p). Unknown genetics_knock down_promote Osteosarcoma 30797154 DOID:3347 D012516 259500 SNHG3 is highly expressed in osteosarcoma, and promotes the invasive and migratory potentials of osteosarcoma cells by absorbing miRNA-151a-3p to upregulate RAB22 A expression. Unknown other Adenocarcinoma of Lung 35159038 DOID:3910 D000077192 We specifically investigated an edited miRNA, miR-151a-3p with an A-to-I editing event at position 3, to determine how its altered expression may be associated with activation of divergent biological pathways between W and B/AA LUAD patients. Unknown other Lung Neoplasms 35159038 DOID:3683 D008175 We specifically investigated an edited miRNA, miR-151a-3p with an A-to-I editing event at position 3, to determine how its altered expression may be associated with activation of divergent biological pathways between W and B/AA LUAD patients. Unknown circulation_biomarker_diagnosis_up Stomach Neoplasms 34336682 DOID:10534 C16 D013274 613659 For GC patients, there were three up-regulated DEmiRNAs (hsa-miR-130b-3p, hsa-miR-151a-3p and hsa-miR-15b-3p) in the serum exosomes, and one up-regulated DEmiRNA (hsa-miR-1246) in the urinary exosomes. Four key exosomal miRNAs (hsa-miR-130b-3p, hsa-miR-151a-3p and hsa-miR-15b-3p) and the interaction network or enrichments based on their targets (TAOK1, CMTM6, SCN3A, WASF3, IGF1, CNOT7, GABRG1, PRKD1) may provide a reference of the molecular mechanisms in the GC development. Unknown other Glaucoma, Open-Angle 34063878 DOID:1067 H40.1 D005902 137750 Here, we demonstrated, for the first time, the differential expression profiling of eight miRNAs when comparing tears from the OHT versus the POAG groups: the miR-26b-5p, miR3p, miR-30e-5p, miR-125b5p, miR5p, miR-151a-3p, miR3p, and the miR-27a-3p. Unknown other Ocular Hypertension 34063878 DOID:9282 H40.05 D009798 Here, we demonstrated, for the first time, the differential expression profiling of eight miRNAs when comparing tears from the OHT versus the POAG groups: the miR-26b-5p, miR3p, miR-30e-5p, miR-125b5p, miR5p, miR-151a-3p, miR3p, and the miR-27a-3p. Unknown genetics_knock down_promote Neuralgia 32860901 D009437 We displayed that miR-151a-3p was greatly reduced in CCI rats and circ_0005075 reversed the repressive effect of miR-151a-3p on neuropathic pain. To sum up, we indicated that loss ofcirc_0005075relieved neuropathic pain progression by inducement of miR-151a-3p and inactivation of NOTCH2 signaling. Unknown other Lewy Body Disease 31592314 DOID:12217 G31.83 D020961 127750 RESULTS: Results uncovered two miRNAs (hsa-miR-451a and hsa-miR5p) significantly down-regulated in AD samples respect to DLB patients, and a set of four miRNAs (hsa-miR-23a-3p, hsa-miR3p, hsa-let-7i-5p, and hsa-miR-151a-3p) significantly decreased in AD respect to controls. Unknown other Alzheimer Disease 31592314 DOID:10652 G30 D000544 RESULTS: Results uncovered two miRNAs (hsa-miR-451a and hsa-miR5p) significantly down-regulated in AD samples respect to DLB patients, and a set of four miRNAs (hsa-miR-23a-3p, hsa-miR3p, hsa-let-7i-5p, and hsa-miR-151a-3p) significantly decreased in AD respect to controls. Unknown other Uveal melanoma 31212861 DOID:6039 C536494 155720 Using a next-generation sequencing approach in 26 UM samples we identified thirteen differentially expressed microRNAs between high-risk UM and low/intermediate-risk UM, including the known oncomirs microRNA5p, microRNA5p, and miR-151a-3p. Unknown genetics_overexpression_promote Glioma 34519373 DOID:3070 D005910 PS137800 To conclude, the present study demonstrates that LINC01123 serves as a sponge for miR-151a and upregulates CENPB expression to increase the radioresistance of glioma cells in vitro and in vivo. Unknown lncRNA target Lung Neoplasms 32633369 DOID:3683 D008175 CONCLUSIONS: Both miR-151a-5p and miR-23b are highly expressed in lung cancer, and the inhibition of miR-151a-5p and miR-23b can restrain the proliferation, invasion and migration of lung cancer A549 cells, thereby promoting the apoptosis of lung cancer A549 cells. Unknown target gene Colorectal Neoplasms 36366788 DOID:0080199 D015179 miR-30d-5p and miR-151a-3p, altered in CRC tissue, were also dysregulated in stool of CRC patients and urine of BC cases, respectively. Unknown therapeutic target Osteoporosis, Postmenopausal 31411118 D015663 In conclusion, our findings suggested that miR-151a-3p contributed to the pathogenesis of postmenopausal osteoporosis, and promoted its progress by targeting SOCS5 and activating JAK2/STAT3 signaling. Thus, anti-miR-151a-3p could be a potential therapeutic strategy for postmenopausal osteoporosis. Unknown lncRNA target Glioblastoma 30992025 DOID:3068 D005909 SBF2-AS1 functions as a ceRNA for miR-151a-3p, leading to the disinhibition of its endogenous target, X-ray repair cross complementing 4 (XRCC4), which enhances DSB repair in GBM cells. Unknown target gene Dermatitis, Atopic 32351034 DOID:3310 L20 D003876 603165 Observational studies revealed dysregulation of miRNAs, including miR-143, miR-146a, miR-151a, miR-155 and miR-223, in AD patients. Unknown other Arm Lymphedema 36232660 Two of the most significantly upregulated microRNAs, miR-199a-3p and miR-151a-3p, were strongly correlated with the onset of lymphedema and diabetes mellitus in the BCRL group. Unknown circulation_biomarker_diagnosis_down urinary system disease Lupus Nephritis 29998838 DOID:0080162 M32.14 D008181 Down-regulation of serum miR-151a-3p is associated with renal tissue activity in class IV lupus nephritis. NO circulation_biomarker_diagnosis_ns Muscular Atrophy 17942673 M62.5 D009133 dysregulation NO circulation_biomarker_diagnosis_ns nervous system disease Parkinson Disease 22003392 DOID:14330 G20 D010300 PS168600 miR-151-3p: differentially expressed in PBMCs (peripheral blood mononuclear cells) of PD patients and controls. NO circulation_biomarker_diagnosis_ns nervous system disease Friedreich Ataxia 29509186 DOID:12705 G11.1 D005621 229300 We found different expression profiles of miRNAs (hsa-miR-128-3p, hsa-miR-625-3p, hsa-miR-130b-5p, hsa-miR-151a-5p, hsa-miR-330-3p, hsa-miR-323a-3p, and hsa-miR-142-3p) between samples from patients and samples from healthy subjects NO circulation_biomarker_diagnosis_ns Hepatitis B, Chronic 29881991 B18.0-.1 D019694 610424 Plasma miRNA-122-5p and miRNA-151a-3p identified as potential biomarkers for liver injury among CHB patients with PNALT. NO circulation_biomarker_diagnosis_ns Esophageal Neoplasms 29923196 C15.9 D004938 133239 deregulation of several circulating miRNAs (i.e., let-7a, miR-21, miR-93, miR-192a, miR-18a, and miR-10b for gastric cancer, and miR-21, miR-375, miR-25-3p, miR-151a-3p, and miR-100-3p for esophageal cancer) NO circulation_biomarker_diagnosis_up disease of cellular proliferation Melanoma 20529253 DOID:1909 C43.9 D008545 155601 miR-151-3p:21 miRNAs that were downregulated in blood cells of melanoma patients and 30 miRNAs that were upregulated in blood cells of melanoma patients NO circulation_biomarker_diagnosis_up disease of cellular proliferation Carcinoma, Renal Cell 22440013 DOID:4450 D002292 144700 miR-151-30: Up-regulated in the blook serum of patients with renal cell carcinoma compared to healthy controls. NO circulation_biomarker_diagnosis_up disease of cellular proliferation Thyroid Neoplasms 22472564 DOID:1781 C73 D013964 188550 The expression of serum let-7e, miR-151-5p, and miR-222 was significantly increased in PTC (papillary thyroid carcinomas ) cases relative to benign cases and healthy controls. Serum let-7e, miR-151-5p, and miR-222 levels were found to be well correlated with certain clinicopathological variables, such as nodal status, tumor size, multifocal lesion status, and Tumor-Node-Metastasis stage. NO circulation_biomarker_diagnosis_up disease of cellular proliferation Stomach Neoplasms 22956063 DOID:10534 C16 D013274 137215 Plasma miRNA-199a-3p and miRNA-151-5p were significantly elevated (p < 0.05) and were significantly reduced after surgery (p < 0.05) in gastric cancer patients. NO circulation_biomarker_diagnosis_up nervous system disease Alzheimer Disease 23895045 DOID:10652 G30.9 D000544 104300 A blood based 12-miRNA signature of Alzheimer disease patients. NO circulation_biomarker_prognosis_down Breast Neoplasms 30109140 D05 D001943 114480 postoperatively downregulated circulating miR-130b-5p, miR-151a-5p, miR-206, and miR-222-3p may be potential biomarkers for breast cancer diagnosis and prognosis NO epigenetics thoracic disease Breast Neoplasms 24257477 DOID:1612 C50 D001943 114480 Our data provide novel evidence of the mechanisms behind miRNA dysregulation in breast cancer. The study contributes to the understanding of how methylation and copy number alterations influence miRNA expression, emphasizing miRNA functionality through redundant encoding, and suggests novel miRNAs important in breast cancer. NO genetics_GWAS thoracic disease Breast Neoplasms 16754881 DOID:1612 C50 D001943 114480 copy number gain NO genetics_GWAS disease of cellular proliferation Melanoma 16754881 DOID:1909 C43.9 D008545 155601 copy number gain NO genetics_GWAS endocrine system disease Ovarian Neoplasms 16754881 DOID:2394 C56 D010051 167000 copy number gain NO genetics_GWAS Nasopharyngeal Neoplasms 23416081 C11.9 D009303 607107 A miR-151 binding site polymorphism in the 3'-untranslated region of the cyclin E1 gene associated with nasopharyngeal carcinoma NO other disease of cellular proliferation Leukemia, Lymphocytic, Chronic, B-Cell 19717645 DOID:1040 C91.1 D015451 151400 correlated with assessment of biological impact on Chronic Lymphocytic Leukemia NO other Glioblastoma 20305651 D005909 significantly increases HCC cell migration and invasion in vitro and in vivo, mainly through miR-151-5p, but not through miR-151-3p NO other hematopoietic system disease Anemia 21921042 DOID:2355 D64.9 D000740 300751 Expression of miR-26b and miR-151-3p were both associated with HbF levels at MTD (maximum tolerated dose). NO other disease of cellular proliferation Prostatic Neoplasms 22928040 DOID:10283 C51 D011471 176807 Genistein Suppresses Prostate Cancer Growth through Inhibition of Oncogenic MicroRNA-151. NO other Acute Kidney Injury 26489516 S37.0 D058186 In mice,miR-122-5p, miR-151a-3p and miR-382-5p specifically reported APAP toxicity -being unaffected by drug-induced kidney injury. Profiling of acetaminophen toxicity identified multiple miRNAs that report acute liver injury and potential biomarkers of drug-induced kidney injury. NO other Chemical and Drug Induced Liver Injury 26489516 S36.11 D056486 In mice,miR-122-5p, miR-151a-3p and miR-382-5p specifically reported APAP toxicity -being unaffected by drug-induced kidney injury. Profiling of acetaminophen toxicity identified multiple miRNAs that report acute liver injury and potential biomarkers of drug-induced kidney injury. NO other disease by infectious agent Hepatitis B 26801621 DOID:2043 B16/18 D006509 610424 We identified miR-24-3p, miR-151a-5p, and miR-425-5p as the most valid combination of reference genes for microRNA RT-qPCR studies in our hepatitis B virus replicating HepG2 cell model. NO other Helicobacter pylori 30324743 B96.81 D016480 600263 the expression of miR-28-3p, miR-143-3p, miR-151a-3p, and miR-148a-3p were closely associated with H pylori infection NO target gene Neoplasms 20445018 C80.1 D009369 miR-151:down-modulating MPL and other targets of miR-28, and of related miR-708 and miR-151, could contribute to MPN pathogenicity NO target gene Cardiovascular Diseases 24088671 D002318 In humans, miR-1248 was found to regulate the expression of mRNAs involved in inflammatory pathways and miR-181a was found to correlate negatively with the pro-inflammatory cytokines IL-6 and TNFα and to correlate positively with the anti-inflammatory cytokines TGFβ and IL-10. NO target gene Neoplasms 24088671 C80.1 D009369 In humans, miR-1248 was found to regulate the expression of mRNAs involved in inflammatory pathways and miR-181a was found to correlate negatively with the pro-inflammatory cytokines IL-6 and TNFα and to correlate positively with the anti-inflammatory cytokines TGFβ and IL-10. NO target gene Asthenozoospermia 26626315 R86.9 D053627 These results indicate that miR-151a-5p may participate in the regulation of cellular respiration and ATP production through targeting Cytb. NO target gene disease by infectious agent Leishmaniasis, Visceral 30125570 DOID:9146 B55.0 D007898 608207 we identified target gene of differentially expressed miRNAs (target miRNAs: hsa-mir-15b, hsa-mir-671, hsa-mir-151a and has-mir-30c) which was confirmed by real time stem-loop PCR NO tissue_expression_down disease of cellular proliferation Carcinoma, Hepatocellular 22027761 DOID:684 C22.0 D006528 114550 This miRNA was down-regulated in HepG2 cells treated with BJA32515. NO tissue_expression_down Carcinoma, Non-Small-Cell Lung 22937028 C34.90 D002289 High expression of miR-100 and low expression of miRNA-93, miRNA-134, miRNA-151 and miRNA-345 were associated with poor survival in both the training and validation cohort. NO tissue_expression_down nervous system disease Amyotrophic Lateral Sclerosis 30210287 DOID:332 G12.21 D000690 PS105400 Results showed that 38 miRNAs were significantly downregulated in sALS NO tissue_expression_ns disease of cellular proliferation Adenocarcinoma of lung 25028925 DOID:3910 C78.00 C538231 211980 The most significant differences in mRNA expression for recurrent tumors compared to non-recurrent tumors were decreases in miR-106b*, -187, -205, -449b, -774* and increases in miR-151-3p, let-7b, miR-215, -520b, and -512-3p. NO tissue_expression_ns disease of cellular proliferation Thyroid cancer, medullary 27666315 DOID:3973 C73 C536914 155240 Selection and validation of miRNAs as normalizers for profiling expression of microRNAs isolated from thyroid fine needle aspiration smears. NO tissue_expression_up reproductive system disease Carcinoma, Endometrioid 19065659 DOID:2870 C54.1 D018269 608089 miR-151: upregulated NO tissue_expression_up disease of cellular proliferation Carcinoma, Hepatocellular 21319996 DOID:684 C22.0 D006528 114550 miR-30d and miR-151 were amplified in ~50% of Hepatitis B Virus-Associated HCC tumor tissues NO tissue_expression_up thoracic disease Breast Neoplasms 22489664 DOID:1612 C50 D001943 114480 miR-151-5p upregulation may suppress metastasis in primary breast tumors. NO