1 hsa-mir-143 ERK5 Obesity 16195701 Modified oligonucleotide complementary to miR-143 effectively suppressed adipocyte differentiation by modulation of its putative target ERK5, a protein previously known to be implicated in MAP kinase signaling pathways. 2 hsa-mir-122 CAT-1 Carcinoma, Hepatocellular 16777601 inhibite CAT-1 3 hsa-mir-20a TGFBR2 Breast Neoplasms 17011485 TGF-b-2 receptor is expressed in the epithelium of breast cancer and can be regulated by miR-20a, which is down- regulated in breast cancer. 4 hsa-mir-22 KIT Thyroid Neoplasms 17012848 Mir-221, mir-22 and mir-146 are significantly upregulated in this disease, whereas the expression of their predicted target gene KIT is lost, concurrently with the miRNA upregulation. 5 hsa-mir-16-1 BCL2 Leukemia, Lymphocytic, Chronic, B-Cell 17012848 It was found that mir-16-1 and mir-15a at 13q14 are deleted in more than 50% patients, with concurrent reduced expression in ~65% patients. Further studies demonstrated that these two miRNAs suppress BCL2 expression and may serve as tumor suppressor genes 6 hsa-mir-127 BCL6 Neoplasms 17012848 For example, mir-127, which is generally expressed in normal cells but absent in cancer cells, was markedly induced after treatment. Intriguingly, a predicted target of mir-127, BCL6, was translationally downregulated after treatment. 7 hsa-mir-221 KIT Thyroid Neoplasms 17012848 Mir-221, mir-22 and mir-146 are significantly upregulated in this disease, whereas the expression of their predicted target gene KIT is lost, concurrently with the miRNA upregulation. 8 hsa-mir-146b KIT Thyroid Neoplasms 17012848 Mir-221, mir-22 and mir-146 are significantly upregulated in this disease, whereas the expression of their predicted target gene KIT is lost, concurrently with the miRNA upregulation. 9 hsa-mir-15a BCL2 Leukemia, Lymphocytic, Chronic, B-Cell 17012848 It was found that mir-16-1 and mir-15a at 13q14 are deleted in more than 50% patients, with concurrent reduced expression in ~65% patients. Further studies demonstrated that these two miRNAs suppress BCL2 expression and may serve as tumor suppressor genes 10 hsa-mir-146a KIT Thyroid Neoplasms 17012848 Mir-221, mir-22 and mir-146 are significantly upregulated in this disease, whereas the expression of their predicted target gene KIT is lost, concurrently with the miRNA upregulation. 11 hsa-mir-19a PTEN Carcinoma, Hepatocellular 17188425 miRNA-19a/b activates PI3K by blocking expression of the tumor suppressor PTEN. 12 hsa-mir-19b-2 PTEN Carcinoma, Hepatocellular 17188425 miRNA-19a/b activates PI3K by blocking expression of the tumor suppressor PTEN. 13 hsa-mir-200a RAB30 Carcinoma, Hepatocellular 17188425 Integration at FRA1A may silence expression of miRNA-200a, which is known to be decreased in HCC compared to nontumor [59] and [65]. Since most miRNAs suppress their target proteins, and miRNA-200a is known to regulate the expression of RAB30, a member of 14 hsa-mir-224 PDGFR Hepatitis, Chronic 17188425 miRNA-224 regulates PDGFR expression, and decreases as disease progresses from chronic hepatitis to cirrhosis [59], suggesting that miRNA normally suppresses PDGFR in the liver until HBV integration and genetic instability upsets this balance. miRNA-224 a 15 hsa-mir-19b-1 PTEN Carcinoma, Hepatocellular 17188425 miRNA-19a/b activates PI3K by blocking expression of the tumor suppressor PTEN. 16 hsa-let-7f-1 Hmga2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 17 hsa-let-7c Hmga2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 18 hsa-let-7f-2 Hmga2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 19 hsa-let-7i Hmga2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 20 hsa-let-7b Hmga2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 21 hsa-let-7a-2 Hmga2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 22 hsa-let-7g Hmga2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 23 hsa-let-7a-3 Hmga2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 24 hsa-let-7a-1 Hmga2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 25 hsa-let-7e Hmga2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 26 hsa-let-7d Hmga2 Neoplasms 17322030 Disrupting the pairing between let-7 and Hmga2 27 hsa-mir-24-1 SLITRK1 Tourette Syndrome 17462786 A mutation in the 3'UTR of the SLITRK1 gene which is associated with Tourette's syndrome was found to enhance repression of the SLITRK mRNA by miR-189, presumably preventing SLITRK1's promotion of dendritic growth. 28 hsa-mir-221 KIT Thyroid Neoplasms 17468766 somatic mutations altering binding sites for miR-221, miR-222 and miR-146 have been observed in the 3?? UTR of the KIT oncogene in papillary thyroid carcinoma. 29 hsa-mir-146b KIT Thyroid Neoplasms 17468766 somatic mutations altering binding sites for miR-221, miR-222 and miR-146 have been observed in the 3?? UTR of the KIT oncogene in papillary thyroid carcinoma. 30 hsa-mir-222 KIT Thyroid Neoplasms 17468766 somatic mutations altering binding sites for miR-221, miR-222 and miR-146 have been observed in the 3?? UTR of the KIT oncogene in papillary thyroid carcinoma. 31 hsa-mir-146a KIT Thyroid Neoplasms 17468766 somatic mutations altering binding sites for miR-221, miR-222 and miR-146 have been observed in the 3?? UTR of the KIT oncogene in papillary thyroid carcinoma. 32 hsa-mir-103a-2 DMPK Myotonic Dystrophy 17697356 These results support a role for miRNAs in DM1 pathogenesis, and, in particular, highlight mir-107 and mir-103 as attractive candidates for binding to DMPK. 33 hsa-mir-103a-1 DMPK Myotonic Dystrophy 17697356 These results support a role for miRNAs in DM1 pathogenesis, and, in particular, highlight mir-107 and mir-103 as attractive candidates for binding to DMPK. 34 hsa-mir-107 DMPK Myotonic Dystrophy 17697356 These results support a role for miRNAs in DM1 pathogenesis, and, in particular, highlight mir-107 and mir-103 as attractive candidates for binding to DMPK. 35 hsa-mir-29c DNMT3A Lung Neoplasms 17890317 mir-29 family (29a,b,c) reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 36 hsa-mir-29c DNMT3b Lung Neoplasms 17890317 mir-29 family (29a,b,c) reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 37 hsa-mir-29a DNMT3A Lung Neoplasms 17890317 mir-29 family (29a,b,c) reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 38 hsa-mir-29a DNMT3b Lung Neoplasms 17890317 mir-29 family (29a,b,c) reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 39 hsa-mir-29b-1 DNMT3A Lung Neoplasms 17890317 mir-29 family (29a,b,c) reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 40 hsa-mir-29b-1 DNMT3b Lung Neoplasms 17890317 mir-29 family (29a,b,c) reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 41 hsa-mir-133a-1 ERG Arrhythmias, Cardiac 17965831 miR-133 was shown to inhibit the expression of ERG (ether-a-go-go-related gene) and cause depression of the potassium channel I(Kr). This inhibition contributed to long QT syndrome and arrhythmia in a diabetic rat model. 42 hsa-mir-29b-1 TCL1 Neoplasms 17965831 Many miRNAs are located at chromosomal break points or fragile sites associated with cancer. Indeed miR-29a and miR-29b are associated with the fragile site FRA7H. In addition, miR-29b along with miR-181b may target the oncogene TCL1 in CLL patients [163] 43 hsa-mir-29b-2 TCL1 Neoplasms 17965831 Many miRNAs are located at chromosomal break points or fragile sites associated with cancer. Indeed miR-29a and miR-29b are associated with the fragile site FRA7H. In addition, miR-29b along with miR-181b may target the oncogene TCL1 in CLL patients [163] 44 hsa-mir-181b TCL1 Neoplasms 17965831 Many miRNAs are located at chromosomal break points or fragile sites associated with cancer. Indeed miR-29a and miR-29b are associated with the fragile site FRA7H. In addition, miR-29b along with miR-181b may target the oncogene TCL1 in CLL patients [163] 45 hsa-let-7i Hmg2A Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 46 hsa-let-7b Hmg2A Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 47 hsa-let-7e Hmg2A Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 48 hsa-let-7f-1 Hmg2A Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 49 hsa-let-7d Hmg2A Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 50 hsa-let-7c Hmg2A Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 51 hsa-let-7a-3 Hmg2A Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 52 hsa-let-7i RAS Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 53 hsa-let-7b RAS Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 54 hsa-let-7e RAS Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 55 hsa-let-7f-1 RAS Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 56 hsa-let-7d RAS Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 57 hsa-let-7c RAS Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 58 hsa-let-7a-3 RAS Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 59 hsa-mir-373 LATS2 Neoplasms 17989227 the related miR-372/373 miRNAs promote tumorigenesis in combination with oncogenic RAS, at least in part by directly inhibiting the tumor suppressor LATS2. 60 hsa-mir-372 LATS2 Neoplasms 17989227 the related miR-372/373 miRNAs promote tumorigenesis in combination with oncogenic RAS, at least in part by directly inhibiting the tumor suppressor LATS2. 61 hsa-let-7a-2 Hmg2A Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 62 hsa-let-7f-2 Hmg2A Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 63 hsa-let-7a-1 Hmg2A Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 64 hsa-let-7g Hmg2A Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 65 hsa-let-7a-2 RAS Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 66 hsa-let-7f-2 RAS Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 67 hsa-let-7a-1 RAS Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 68 hsa-let-7g RAS Neoplasms 17989227 let-7 family members have been suggested to serve as tumor suppressors by directly inhibiting the Hmg2A and RAS protooncogenes 69 hsa-mir-433 FGF20 Parkinson Disease 18252210 Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. 70 hsa-mir-124-1 CDK6 Medulloblastoma 18607543 miR-124: regulates cyclin dependent kinase 6 71 hsa-mir-124-2 CDK6 Medulloblastoma 18607543 miR-124: regulates cyclin dependent kinase 6 72 hsa-mir-124-3 CDK6 Medulloblastoma 18607543 miR-124: regulates cyclin dependent kinase 6 73 hsa-mir-451a MDR Neoplasms 18619946 miR-451: miR-27a and miR-451 regulate expression of MDR1/P-glycoprotein 74 hsa-mir-27a MDR Neoplasms 18619946 miR-27a: miR-27a and miR-451 regulate expression of MDR1/P-glycoprotein 75 hsa-mir-451a ABCB1 Neoplasms 18619946 miR-451: miR-27a and miR-451 regulate expression of MDR1/P-glycoprotein 76 hsa-mir-27a ABCB1 Neoplasms 18619946 miR-27a: miR-27a and miR-451 regulate expression of MDR1/P-glycoprotein 77 hsa-let-7f-1 ITGB3 Melanoma 18679415 let-7f: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 78 hsa-let-7a-2 ITGB3 Melanoma 18679415 let-7a: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 79 hsa-let-7b ITGB3 Melanoma 18679415 let-7b: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 80 hsa-let-7a-1 ITGB3 Melanoma 18679415 let-7a: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 81 hsa-let-7i ITGB3 Melanoma 18679415 let-7i: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 82 hsa-let-7a-3 ITGB3 Melanoma 18679415 let-7a: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 83 hsa-let-7d ITGB3 Melanoma 18679415 let-7d: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 84 hsa-let-7c ITGB3 Melanoma 18679415 let-7c: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 85 hsa-let-7g ITGB3 Melanoma 18679415 let-7g: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 86 hsa-let-7e ITGB3 Melanoma 18679415 let-7e: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 87 hsa-let-7f-2 ITGB3 Melanoma 18679415 let-7f: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma 88 hsa-mir-659 GRN Dementia 18723524 miR-659: Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia 89 hsa-let-7a-1 CASP3 Neoplasms 18758960 Let-7a: Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3 90 hsa-let-7a-2 CASP3 Neoplasms 18758960 Let-7a: Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3 91 hsa-let-7a-3 CASP3 Neoplasms 18758960 Let-7a: Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3 92 hsa-mir-302b CCND2 Carcinoma, Embryonal 18930031 miR-302b: "miR-302b maintains ""stemness"" of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression" 93 hsa-mir-15a Cdc25A Polycystic Kidney Diseases 18949056 miR-15a: MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis 94 hsa-mir-21 PDCD4 Glioblastoma 19013014 miR-21: MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G 95 hsa-mir-29a CDC42 Neoplasms 19079265 miR-29a: miR-29 directly suppress p85 alpha and CDC42, both of which negatively regulate p53 96 hsa-mir-29a PIK3R1 Neoplasms 19079265 miR-29a: miR-29 directly suppress p85 alpha and CDC42, both of which negatively regulate p53 97 hsa-mir-15a CCNE1 Head and Neck Neoplasms 19117988 miR-15a: feed-forward loop: PKCalpha down-regulates miR-15a, which directly inhibits protein synthesis of cyclin E 98 hsa-mir-15a CCNE2 Head and Neck Neoplasms 19117988 miR-15a: feed-forward loop: PKCalpha down-regulates miR-15a, which directly inhibits protein synthesis of cyclin E 99 hsa-mir-221 cKit Melanoma 19126397 miR-221: mir-221 can directly interact with c-kit 3'UTR and inhibit cKit protein translation 100 hsa-mir-1-2 PP2A Arrhythmias, Cardiac 19131648 miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2 101 hsa-mir-1-1 PP2A Arrhythmias, Cardiac 19131648 miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2 102 hsa-mir-101-1 FOS Carcinoma, Hepatocellular 19133651 miR-101: MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene 103 hsa-mir-101-2 FOS Carcinoma, Hepatocellular 19133651 miR-101: MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene 104 hsa-mir-93 p21 Stomach Neoplasms 19153141 miR-93: inhibite p21,p27, and p57 105 hsa-mir-93 p27 Stomach Neoplasms 19153141 miR-93: inhibite p21,p27, and p57 106 hsa-mir-93 p57 Stomach Neoplasms 19153141 miR-93: inhibite p21,p27, and p57 107 hsa-mir-222 p21 Stomach Neoplasms 19153141 miR-222: inhibite p21,p27, and p57 108 hsa-mir-222 p27 Stomach Neoplasms 19153141 miR-222: inhibite p21,p27, and p57 109 hsa-mir-222 p57 Stomach Neoplasms 19153141 miR-222: inhibite p21,p27, and p57 110 hsa-mir-221 p21 Stomach Neoplasms 19153141 miR-221: inhibite p21,p27, and p57 111 hsa-mir-221 p27 Stomach Neoplasms 19153141 miR-221: inhibite p21,p27, and p57 112 hsa-mir-221 p57 Stomach Neoplasms 19153141 miR-221: inhibite p21,p27, and p57 113 hsa-mir-25 p21 Stomach Neoplasms 19153141 miR-25: inhibite p21,p27, and p57 114 hsa-mir-25 p27 Stomach Neoplasms 19153141 miR-25: inhibite p21,p27, and p57 115 hsa-mir-25 p57 Stomach Neoplasms 19153141 miR-25: inhibite p21,p27, and p57 116 hsa-mir-106b p21 Stomach Neoplasms 19153141 miR-106b: inhibite p21,p27, and p57 117 hsa-mir-106b p27 Stomach Neoplasms 19153141 miR-106b: inhibite p21,p27, and p57 118 hsa-mir-106b p57 Stomach Neoplasms 19153141 miR-106b: inhibite p21,p27, and p57 119 hsa-mir-141 CDH1 Neoplasms 19182522 miR-141: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 120 hsa-mir-141 ZEB1 Neoplasms 19182522 miR-141: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 121 hsa-mir-141 ZEB2 Neoplasms 19182522 miR-141: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 122 hsa-mir-200b CDH1 Neoplasms 19182522 miR-200b: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 123 hsa-mir-200b ZEB1 Neoplasms 19182522 miR-200b: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 124 hsa-mir-200b ZEB2 Neoplasms 19182522 miR-200b: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 125 hsa-mir-200c CDH1 Neoplasms 19182522 miR-200c: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 126 hsa-mir-200c ZEB1 Neoplasms 19182522 miR-200c: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 127 hsa-mir-200c ZEB2 Neoplasms 19182522 miR-200c: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 128 hsa-mir-200a CDH1 Neoplasms 19182522 miR-200a: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 129 hsa-mir-200a ZEB1 Neoplasms 19182522 miR-200a: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 130 hsa-mir-200a ZEB2 Neoplasms 19182522 miR-200a: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 131 hsa-mir-429 CDH1 Neoplasms 19182522 miR-429: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 132 hsa-mir-429 ZEB1 Neoplasms 19182522 miR-429: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 133 hsa-mir-429 ZEB2 Neoplasms 19182522 miR-429: miR-200 family:inhibit the initiating step of metastasis, epithelial-mesenchymal transition (EMT), by maintaining the epithelial phenotype through direct targeting of transcriptional repressors of E-cadherin, ZEB1 and ZEB2 134 hsa-mir-1-2 CAMK2G Cardiomegaly 19188439 miR-1: MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes 135 hsa-mir-1-2 Mef2a Cardiomegaly 19188439 miR-1: MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes 136 hsa-mir-1-1 CAMK2G Cardiomegaly 19188439 miR-1: MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes 137 hsa-mir-1-1 Mef2a Cardiomegaly 19188439 miR-1: MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes 138 hsa-mir-182 FOXO3 Melanoma 19188590 miR-182: Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor 139 hsa-mir-18b BTG2 Carcinoma, Hepatocellular 19203451 miR-18: target BTG2 140 hsa-mir-18a BTG2 Carcinoma, Hepatocellular 19203451 miR-18: target BTG2 141 hsa-mir-10a Hoxd4 Breast Neoplasms 19232136 miR-10a: miR-10a inhibits transcriptional of Hoxd4 142 hsa-mir-34b CREB1 Leukemia, Myeloid, Acute 19258499 miR-34b: miR-34b targets cyclic AMP-responsive element binding protein 143 hsa-mir-101-1 EZH2 Urinary Bladder Neoplasms 19258506 miR-101: putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2 144 hsa-mir-101-2 EZH2 Urinary Bladder Neoplasms 19258506 miR-101: putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2 145 hsa-mir-222 p27Kip1 Marek Disease 19264608 miR-222: miR-221/222 target p27Kip1 in Marek's disease virus-transformed tumour cell line MSB-1 146 hsa-mir-221 p27Kip1 Marek Disease 19264608 miR-221: miR-221/222 target p27Kip1 in Marek's disease virus-transformed tumour cell line MSB-1 147 hsa-mir-21 MARCKS Prostatic Neoplasms 19302977 miR-21: MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells 148 hsa-mir-21 PDCD4 Myocardial Infarction 19336275 miR-21: miR-21 can protect this by targeting PDCD4 149 hsa-mir-21 PDCD4 Cardiomyopathy, Hypertrophic 19336275 miR-21: miR-21 can protect this by targeting PDCD4 150 hsa-mir-21 PDCD4 Myocardial Reperfusion Injury 19336275 miR-21: miR-21 can protect this by targeting PDCD4 151 hsa-mir-21 PDCD4 Heart Failure 19336275 miR-21: miR-21 can protect this by targeting PDCD4 152 hsa-mir-21 PDCD4 Myocardial Ischemia 19336275 miR-21: miR-21 can protect this by targeting PDCD4 153 hsa-mir-21 PDCD4 Myocytes, Cardiac 19336275 MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4 154 hsa-mir-92a-1 VHL Leukemia, Lymphocytic, Chronic, B-Cell 19336759 miR-92-1: overexpressed, can target the VHL transcript 155 hsa-mir-145 PDGFD Prostatic Neoplasms 19544444 regulates PDGF-D, which mediate epithelial-mesenchymal transition, adhesion, and invasion, which was associated with the downregulation of ZEB1, ZEB2,and Snail2 expression; 156 hsa-mir-429 EP300 Adenocarcinoma 19569050 regulate EP300, a metastasis suppressor gene; these miRs are related to reduced EP300 mRNA and protein; 157 hsa-mir-200c EP300 Adenocarcinoma 19569050 regulate EP300, a metastasis suppressor gene; these miRs are related to reduced EP300 mRNA and protein; 158 hsa-mir-200b EP300 Adenocarcinoma 19569050 regulate EP300, a metastasis suppressor gene; these miRs are related to reduced EP300 mRNA and protein; 159 hsa-mir-31 FOXO1 Breast Neoplasms 19574223 Coordinate Regulate FOXO1; highly expressed; a novel mechanism of FOXO1 regulation, and targeting of FOXO1 by microRNAs may contribute to transformation or maintenance of an oncogenic state in breast cancer cells 160 hsa-mir-182 FOXO1 Breast Neoplasms 19574223 Coordinate Regulate FOXO1; highly expressed; a novel mechanism of FOXO1 regulation, and targeting of FOXO1 by microRNAs may contribute to transformation or maintenance of an oncogenic state in breast cancer cells 161 hsa-mir-96 FOXO1 Breast Neoplasms 19574223 Coordinate Regulate FOXO1; highly expressed; a novel mechanism of FOXO1 regulation, and targeting of FOXO1 by microRNAs may contribute to transformation or maintenance of an oncogenic state in breast cancer cells 162 hsa-mir-331 ERBB2 Prostatic Neoplasms 19584056 miR-311-3p regulate ERBB-2 expression and androgen receptor signaling in prostate cancer 163 hsa-mir-27a ERBB2 Prostatic Neoplasms 19584056 decreased in prostate cancer; Regulates ERBB-2 Expression; blocked downstream phosphatidylinositol 3-kinase/AKT signaling, reducing activity of an androgen-stimulated prostate-specific antigen promoter and blocking prostate-specific antigen expression 164 hsa-mir-200b BMI1 Breast Neoplasms 19665978 downregulated, modulate Expression of BMI1, suppressed tumor formation of normal stem cell 165 hsa-mir-200c LRP1 Neoplasms 19665999 inhibits through down-regulating LRP1 166 hsa-mir-205 JAK2 Hodgkin Disease 19666866 Regulates JAK2, prognostic impact 167 hsa-mir-98 FUS1 Lung Neoplasms 19671678 regulate tumor suppressor gene FUS1 168 hsa-mir-93 FUS1 Lung Neoplasms 19671678 regulate tumor suppressor gene FUS1 169 hsa-mir-197 FUS1 Lung Neoplasms 19671678 regulate tumor suppressor gene FUS1 170 hsa-mir-17 BCL2 Glioblastoma 19676043 inhibite Bcl-2 and Mcl-1, induce apoptosis 171 hsa-mir-18a MCL1 Glioblastoma 19676043 inhibite Bcl-2 and Mcl-1, induce apoptosis 172 hsa-mir-19a MCL1 Glioblastoma 19676043 inhibite Bcl-2 and Mcl-1, induce apoptosis 173 hsa-mir-17 MCL1 Glioblastoma 19676043 inhibite Bcl-2 and Mcl-1, induce apoptosis 174 hsa-mir-18a BCL2 Glioblastoma 19676043 inhibite Bcl-2 and Mcl-1, induce apoptosis 175 hsa-mir-19a BCL2 Glioblastoma 19676043 inhibite Bcl-2 and Mcl-1, induce apoptosis 176 hsa-mir-155 KGF Fibroblasts 19701459 upregulates and target KGF 3'-UTR 177 hsa-mir-206 MET Rhabdomyosarcoma 19710019 inhibits rhabdomyosarcoma through downregulating c-Met 178 hsa-mir-206 MET Rhabdomyosarcoma 19710019 MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development 179 hsa-mir-1-1 MET Rhabdomyosarcoma 19710019 inhibits rhabdomyosarcoma through downregulating c-Met 180 hsa-mir-1-2 MET Rhabdomyosarcoma 19710019 inhibits rhabdomyosarcoma through downregulating c-Met 181 hsa-mir-15a BCL2 Arthritis 19714650 induction of apoptosis in the synovium of mice,suppresses apoptosis through inhibition of Bcl-2 182 hsa-mir-15a BCL2 Arthritis, Psoriatic 19714650 suppresses apoptosis through inhibition of Bcl-2 183 hsa-mir-133a-1 KLF15 Myocytes, Cardiac 19720047 MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes 184 hsa-mir-133b KLF15 Myocytes, Cardiac 19720047 MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes 185 hsa-mir-133a-2 KLF15 Myocytes, Cardiac 19720047 MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes 186 hsa-mir-206 Notch3 Neoplasms 19723635 inhibits Notch3 187 hsa-mir-125b-1 BMPR1B Breast Neoplasms 19738052 hsa-miR-125b binding site in BMPR1B is Associated with Breast cancer pathogenesis 188 hsa-mir-125b-2 BMPR1B Breast Neoplasms 19738052 hsa-miR-125b binding site in BMPR1B is Associated with Breast cancer pathogenesis 189 hsa-let-7a-3 KRAS Carcinoma 20033209 let-7a:The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice 190 hsa-let-7a-2 KRAS Carcinoma 20033209 let-7a:The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice 191 hsa-let-7a-1 KRAS Carcinoma 20033209 let-7a:The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice 192 hsa-let-7a-3 MYC Carcinoma 20033209 let-7a:The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice 193 hsa-let-7a-2 MYC Carcinoma 20033209 let-7a:The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice 194 hsa-let-7a-1 MYC Carcinoma 20033209 let-7a:The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice 195 hsa-mir-491 BCL2L1 Colorectal Neoplasms 20039318 miR-491:Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-X(L) in colorectal cancer cells 196 hsa-mir-34a BCL2 Neoplasms 20049626 miR-34a:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 197 hsa-mir-34a E2F1 Neoplasms 20049626 miR-34a:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 198 hsa-mir-34a E2F3 Neoplasms 20049626 miR-34a:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 199 hsa-mir-34a RB1 Neoplasms 20049626 miR-34a:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 200 hsa-mir-34a P53 Neoplasms 20049626 miR-34a:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 201 hsa-mir-34c BCL2 Neoplasms 20049626 miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 202 hsa-mir-34c E2F1 Neoplasms 20049626 miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 203 hsa-mir-34c E2F3 Neoplasms 20049626 miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 204 hsa-mir-34c RB1 Neoplasms 20049626 miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 205 hsa-mir-34c P53 Neoplasms 20049626 miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 206 hsa-mir-125a BCL2 Neoplasms 20049626 miR-125:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 207 hsa-mir-125a E2F1 Neoplasms 20049626 miR-125:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 208 hsa-mir-125a E2F3 Neoplasms 20049626 miR-125:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 209 hsa-mir-125a RB1 Neoplasms 20049626 miR-125:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 210 hsa-mir-125a P53 Neoplasms 20049626 miR-125:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 211 hsa-mir-34b BCL2 Neoplasms 20049626 miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 212 hsa-mir-34b E2F1 Neoplasms 20049626 miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 213 hsa-mir-34b E2F3 Neoplasms 20049626 miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 214 hsa-mir-34b RB1 Neoplasms 20049626 miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 215 hsa-mir-34b P53 Neoplasms 20049626 miR-34c:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 216 hsa-mir-150 BCL2 Neoplasms 20049626 miR-150:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 217 hsa-mir-150 E2F1 Neoplasms 20049626 miR-150:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 218 hsa-mir-150 E2F3 Neoplasms 20049626 miR-150:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 219 hsa-mir-150 RB1 Neoplasms 20049626 miR-150:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 220 hsa-mir-150 P53 Neoplasms 20049626 miR-150:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 221 hsa-mir-106a BCL2 Neoplasms 20049626 miR-106:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 222 hsa-mir-106a E2F1 Neoplasms 20049626 miR-106:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 223 hsa-mir-106a E2F3 Neoplasms 20049626 miR-106:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 224 hsa-mir-106a RB1 Neoplasms 20049626 miR-106:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 225 hsa-mir-106a P53 Neoplasms 20049626 miR-106:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 226 hsa-mir-16-2 BCL2 Neoplasms 20049626 miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 227 hsa-mir-16-2 E2F1 Neoplasms 20049626 miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 228 hsa-mir-16-2 E2F3 Neoplasms 20049626 miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 229 hsa-mir-16-2 RB1 Neoplasms 20049626 miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 230 hsa-mir-16-2 P53 Neoplasms 20049626 miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 231 hsa-mir-16-1 BCL2 Neoplasms 20049626 miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 232 hsa-mir-16-1 E2F1 Neoplasms 20049626 miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 233 hsa-mir-16-1 E2F3 Neoplasms 20049626 miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 234 hsa-mir-16-1 RB1 Neoplasms 20049626 miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 235 hsa-mir-16-1 P53 Neoplasms 20049626 miR-16:Our results also indicated that miR-16/34a-c, miR-17-5p, miR-125, miR-106, and miR-150 were the upstream factors, which could regulate the expression of BCL-2, E2F1, E2F3, RB1, and P53 236 hsa-mir-205 MED1 Trophoblasts 20065103 miR-205:MiR-205 silences MED1 in hypoxic primary human trophoblasts; a set of seven miRNAs (miR-93, miR-205, miR-224, miR-335, miR-424, miR-451, and miR-491) that are differentially regulated in primary trophoblasts 237 hsa-mir-19a ESR Neuroblastoma 20080637 miR-18a and miR-19a target and repress the expression of estrogen receptor-alpha (ESR1) 238 hsa-mir-18a ESR Neuroblastoma 20080637 miR-18a and miR-19a target and repress the expression of estrogen receptor-alpha (ESR1) 239 hsa-mir-9-2 NFKB1 Stomach Neoplasms 20102618 miR-9 targets NF-kappaB1 and regulates gastric cancer cell growth 240 hsa-mir-9-3 NFKB1 Stomach Neoplasms 20102618 miR-9 targets NF-kappaB1 and regulates gastric cancer cell growth 241 hsa-mir-9-1 NFKB1 Stomach Neoplasms 20102618 miR-9 targets NF-kappaB1 and regulates gastric cancer cell growth 242 hsa-mir-373 RECK Neoplasms 20154725 miR-373:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373) 243 hsa-mir-21 RECK Neoplasms 20154725 miR-21:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373) 244 hsa-mir-15b RECK Neoplasms 20154725 miR-15b:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373) 245 hsa-mir-16-2 RECK Neoplasms 20154725 miR-16:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373) 246 hsa-mir-16-1 RECK Neoplasms 20154725 miR-16:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373) 247 hsa-mir-372 RECK Neoplasms 20154725 miR-372:RECK is a target of at least three groups of miRNAs (miR-15b/16, miR-21 and miR-372/373) 248 hsa-mir-433 HDAC6 Chondrodysplasia Punctata 20181727 miR-433:A mutation in the 3'-UTR of the HDAC6 gene abolishing the post-transcriptional regulation mediated by hsa-miR-433 is linked to a new form of dominant X-linked chondrodysplasia 249 hsa-mir-29a NAV3 Alzheimer Disease 20202123 miR-29a decreased in Alzheimer disease brains targets neuron navigator-3 250 hsa-mir-21 PTEN Lung Neoplasms 20223231 MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC) 251 hsa-mir-20b HIF1A Breast Neoplasms 20232316 miR-20b modulates VEGF expression by targeting HIF-1alpha and STAT3 in MCF-7 breast cancer cells 252 hsa-mir-20b STAT3 Breast Neoplasms 20232316 miR-20b:miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells 253 hsa-mir-218-2 ROBO1 Stomach Neoplasms 20300657 MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor. 254 hsa-mir-218-1 ROBO1 Stomach Neoplasms 20300657 MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor. 255 hsa-mir-193b CCND1 Melanoma 20304954 MicroRNA-193b Represses Cell Proliferationand Regulates Cyclin D1 in Melanoma 256 hsa-let-7g COL1A2 Carcinoma, Hepatocellular 20338660 Let-7g targets collagen type I alpha2 and inhibits cell migration in hepatocellular carcinoma. 257 hsa-mir-21 TIMP3 Breast Neoplasms 20346171 our data suggests that miR-21 could promote invasion in breast cancer cells via its regulation of TIMP3 258 hsa-let-7g BCL2L1 Carcinoma, Hepatocellular 20347499 hsa-let-7g:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 259 hsa-let-7a-1 BCL2L1 Carcinoma, Hepatocellular 20347499 hsa-let-7a:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 260 hsa-let-7d BCL2L1 Carcinoma, Hepatocellular 20347499 hsa-let-7d:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 261 hsa-let-7f-2 BCL2L1 Carcinoma, Hepatocellular 20347499 hsa-let-7f:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 262 hsa-let-7f-1 BCL2L1 Carcinoma, Hepatocellular 20347499 hsa-let-7f:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 263 hsa-let-7e BCL2L1 Carcinoma, Hepatocellular 20347499 hsa-let-7e:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 264 hsa-let-7a-2 BCL2L1 Carcinoma, Hepatocellular 20347499 hsa-let-7a:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 265 hsa-let-7c BCL2L1 Carcinoma, Hepatocellular 20347499 hsa-let-7c:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 266 hsa-let-7a-3 BCL2L1 Carcinoma, Hepatocellular 20347499 hsa-let-7a:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 267 hsa-let-7i BCL2L1 Carcinoma, Hepatocellular 20347499 hsa-let-7i:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 268 hsa-let-7b BCL2L1 Carcinoma, Hepatocellular 20347499 hsa-let-7b:The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 269 hsa-let-7a-3 BCL2L1 Carcinoma, Hepatocellular 20347499 The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma 270 hsa-mir-34a Notch1 Carcinoma 20351093 miR-34a:MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells 271 hsa-mir-34a JAG1 Carcinoma 20351093 miR-34a:MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells 272 hsa-mir-155 SOCS1 Breast Neoplasms 20354188 MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene 273 hsa-mir-155 FOXO3a Breast Neoplasms 20371610 MicroRNA-155 regulates cell survival, growth and chemosensitivity by targeting FOXO3a in breast cancer 274 hsa-mir-155 FOXO3a Breast Neoplasms 20371610 miR-155:miR-155 is a critical therapeutic target in breast cancer; MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer 275 hsa-mir-512-2 C-FLIP Carcinoma, Hepatocellular 20372864 miR-512-3p:Inhibition of c-FLIP expression by miR-512-3p contributes to taxol-induced apoptosis in hepatocellular carcinoma cells 276 hsa-mir-512-1 C-FLIP Carcinoma, Hepatocellular 20372864 miR-512-3p:Inhibition of c-FLIP expression by miR-512-3p contributes to taxol-induced apoptosis in hepatocellular carcinoma cells 277 hsa-mir-219-1 ID3 Child Development Disorders, Pervasive 20374639 Putative gene targets (ID3 and PLK2) of two RT-PCR-confirmed brain-specific miRNAs (hsa-miR-29b and hsa-miR-219-5p),were validated by miRNA overexpression or knockdown assays 278 hsa-mir-219-1 PLK2 Child Development Disorders, Pervasive 20374639 Putative gene targets (ID3 and PLK2) of two RT-PCR-confirmed brain-specific miRNAs (hsa-miR-29b and hsa-miR-219-5p),were validated by miRNA overexpression or knockdown assays 279 hsa-mir-219-2 ID3 Child Development Disorders, Pervasive 20374639 Putative gene targets (ID3 and PLK2) of two RT-PCR-confirmed brain-specific miRNAs (hsa-miR-29b and hsa-miR-219-5p),were validated by miRNA overexpression or knockdown assays 280 hsa-mir-219-2 PLK2 Child Development Disorders, Pervasive 20374639 Putative gene targets (ID3 and PLK2) of two RT-PCR-confirmed brain-specific miRNAs (hsa-miR-29b and hsa-miR-219-5p),were validated by miRNA overexpression or knockdown assays 281 hsa-mir-29b ID3 Child Development Disorders, Pervasive 20374639 Putative gene targets (ID3 and PLK2) of two RT-PCR-confirmed brain-specific miRNAs (hsa-miR-29b and hsa-miR-219-5p),were validated by miRNA overexpression or knockdown assays 282 hsa-mir-29b PLK2 Child Development Disorders, Pervasive 20374639 Putative gene targets (ID3 and PLK2) of two RT-PCR-confirmed brain-specific miRNAs (hsa-miR-29b and hsa-miR-219-5p),were validated by miRNA overexpression or knockdown assays 283 hsa-mir-148a MSK1 Prostatic Neoplasms 20406806 miR-148a:MiR-148a attenuates paclitaxel resistance of hormone-refractory, drug-resistant prostate cancer PC3 cells by regulating MSK1 expression 284 hsa-mir-19a p21 Leukemia, Myeloid, Acute 20406979 miR-19a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 285 hsa-mir-18a p21 Leukemia, Myeloid, Acute 20406979 miR-18a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 286 hsa-mir-92a-2 p21 Leukemia, Myeloid, Acute 20406979 miR-92a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 287 hsa-mir-92a-1 p21 Leukemia, Myeloid, Acute 20406979 miR-92a:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 288 hsa-mir-17 p21 Leukemia, Myeloid, Acute 20406979 miR-17:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 289 hsa-mir-19b-2 p21 Leukemia, Myeloid, Acute 20406979 miR-19b:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 290 hsa-mir-19a p21 Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression 291 hsa-mir-19b-1 p21 Leukemia, Myeloid, Acute 20406979 miR-19b:The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression 292 hsa-mir-19b-2 p21 Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression 293 hsa-mir-20a p21 Leukemia 20406979 The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression 294 hsa-mir-151a MPL Neoplasms 20445018 miR-151:down-modulating MPL and other targets of miR-28, and of related miR-708 and miR-151, could contribute to MPN pathogenicity 295 hsa-mir-708 MPL Neoplasms 20445018 miR-708:down-modulating MPL and other targets of miR-28, and of related miR-708 and miR-151, could contribute to MPN pathogenicity 296 hsa-mir-28 MPL Neoplasms 20445018 miR-28:down-modulating MPL and other targets of miR-28, and of related miR-708 and miR-151, could contribute to MPN pathogenicity 297 hsa-mir-155 CYR61 Pre-Eclampsia 20452491 miR-155:MicroRNA-155 contributes to preeclampsia by down-regulating CYR61 298 hsa-mir-20a APP Ovarian Neoplasms 20458444 miR-20a:miR-20a promotes proliferation and invasion by targeting APP in human ovarian cancer cells 299 hsa-mir-25 FXR1P Muscular Dystrophy, Facioscapulohumeral 20519410 miR-25:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence 300 hsa-mir-32 FXR1P Muscular Dystrophy, Facioscapulohumeral 20519410 miR-32:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence 301 hsa-mir-92a-1 FXR1P Muscular Dystrophy, Facioscapulohumeral 20519410 miR-92:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence 302 hsa-mir-92a-2 FXR1P Muscular Dystrophy, Facioscapulohumeral 20519410 miR-92:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence 303 hsa-mir-363 FXR1P Muscular Dystrophy, Facioscapulohumeral 20519410 miR-363:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence 304 hsa-mir-367 FXR1P Muscular Dystrophy, Facioscapulohumeral 20519410 miR-367:We report for the first time that FXR1P is regulated through miRNA binding, with one site being the miR-25/32/92/363/367 seed sequence 305 hsa-mir-661 PVRL1 Breast Neoplasms 20543867 miR-661:miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers 306 hsa-mir-661 STARD10 Breast Neoplasms 20543867 miR-661:miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers 307 hsa-mir-375 JAK2 Stomach Neoplasms 20548334 MiR-375:MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2 308 hsa-mir-22 MYCBP Neoplasms 20562918 miR-22:miR-22 acts as a tumor suppressor through direct repression of MYCBP expression and subsequent reduction of oncogenic c-Myc activities. 309 hsa-mir-185 SIX1 Neoplasms 20603620 miRNA-185:MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers 310 hsa-mir-96 KRAS Pancreatic Neoplasms 20610624 miRNA-96:miRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer 311 hsa-mir-149 AKT1 Neoplasms 20623644 miR-149:miR-149* induces apoptosis by inhibiting Akt1 and E2F1 in human cancer cells 312 hsa-mir-149 E2F1 Neoplasms 20623644 miR-149:miR-149* induces apoptosis by inhibiting Akt1 and E2F1 in human cancer cells 313 hsa-mir-27a HIPK2 Ovarian Neoplasms 20624637 MiR-27a:MiR-27a modulates MDR1/P-glycoprotein expression by targeting HIPK2 in human ovarian cancer cells 314 hsa-mir-137 MITF Melanoma 20644734 miR-137:Our data show that miR-148 and miR-137 present an additional level of regulating Mitf expression in melanocytes and melanoma cells. 315 hsa-mir-148a MITF Melanoma 20644734 miR-148:Our data show that miR-148 and miR-137 present an additional level of regulating Mitf expression in melanocytes and melanoma cells. 316 hsa-mir-24-1 DND1 Carcinoma, Squamous Cell 20816961 miR-24:MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma 317 hsa-mir-24-2 DND1 Carcinoma, Squamous Cell 20816961 miR-24:MicroRNA-24 targeting RNA-binding protein DND1 in tongue squamous cell carcinoma 318 hsa-mir-128-2 NTRK3 Neuroblastoma 21143953 Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells. 319 hsa-mir-128-1 NTRK3 Neuroblastoma 21143953 Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells. 320 hsa-mir-21 THRB Thyroid Neoplasms 21159845 Papillary Thyroid Carcinoma (PTC). Direct interaction with THRB was shown for miR-21 and miR-146a. 321 hsa-mir-146a THRB Thyroid Neoplasms 21159845 Papillary Thyroid Carcinoma (PTC). Direct interaction with THRB was shown for miR-21 and miR-146a. 322 hsa-mir-569 SPI1 Lupus Erythematosus, Systemic 21162035 Association of a functional polymorphism in the 3' untranslated region of SPI1 with systemic lupus erythematosus. 323 hsa-mir-107 COFILIN Alzheimer Disease 21179570 microRNAs 103 and 107 repress translation of cofilin, and that reduced levels of miR-103 or miR-107 are associated with elevated cofilin protein levels and formation of rod-like structures in a transgenic mouse model of AD 324 hsa-mir-103a-2 COFILIN Alzheimer Disease 21179570 microRNAs 103 and 107 repress translation of cofilin, and that reduced levels of miR-103 or miR-107 are associated with elevated cofilin protein levels and formation of rod-like structures in a transgenic mouse model of AD 325 hsa-mir-103a-1 COFILIN Alzheimer Disease 21179570 microRNAs 103 and 107 repress translation of cofilin, and that reduced levels of miR-103 or miR-107 are associated with elevated cofilin protein levels and formation of rod-like structures in a transgenic mouse model of AD 326 hsa-mir-185 RhoA Colorectal Neoplasms 21186079 miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells.miR-185 is a negative regulator of RhoA and Cdc42 and their cellular activities, and could inhibit proliferation and invasion of colorectal cancer 327 hsa-mir-185 CDC42 Colorectal Neoplasms 21186079 miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells.miR-185 is a negative regulator of RhoA and Cdc42 and their cellular activities, and could inhibit proliferation and invasion of colorectal cancer 328 hsa-mir-21 PTEN Leukemia 21187093 Involvement of miR-21 in resistance to daunorubicin by regulating PTEN expression in the leukaemia K562 cell line. 329 hsa-mir-26a-1 EZH2 Nasopharyngeal Neoplasms 21199804 MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2 330 hsa-mir-26a-2 EZH2 Nasopharyngeal Neoplasms 21199804 MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2 331 hsa-mir-203 BCL2L2 Urinary Bladder Neoplasms 21205209 microRNA-203 suppresses bladder cancer development by repressing bcl-w expression. 332 hsa-mir-195 p53 Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 333 hsa-mir-16-2 p53 Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 334 hsa-mir-16-1 p53 Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 335 hsa-mir-15b p53 Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 336 hsa-mir-15a p53 Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 337 hsa-mir-34c p53 Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 338 hsa-mir-34b p53 Leukemia, Lymphocytic, Chronic, B-Cell 21205967 A microRNA/TP53 feedback circuitry is associated with CLL pathogenesis and outcome. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. 339 hsa-mir-31 DMD Muscular Dystrophy, Duchenne 21212803 miR-31 represses dystrophin expression by targeting its 3' untranslated region. 340 hsa-mir-214 PLXNB1 Uterine Cervical Neoplasms 21216304 Plexin-B1 is a target of miR-214 in cervical cancer and promotes the growth and invasion of HeLa Cells. 341 hsa-mir-328 BCRP Breast Neoplasms 21219875 Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328; -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells. 342 hsa-mir-520h BCRP Breast Neoplasms 21219875 Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328; -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells. 343 hsa-mir-519c BCRP Breast Neoplasms 21219875 Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328; -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells. 344 hsa-mir-616 TFPI2 Prostatic Neoplasms 21224345 microRNA-616 Induces Androgen-Independent Growth of Prostate Cancer Cells by Suppressing Expression of Tissue Factor Pathway Inhibitor TFPI-2. 345 hsa-mir-376c ACVR1C Ovarian Neoplasms 21224400 MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance. 346 hsa-mir-200c ZEB1 Breast Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. 347 hsa-mir-200a ZEB1 Pancreatic Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. 348 hsa-mir-200c ZEB1 Pancreatic Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. 349 hsa-mir-200b ZEB1 Breast Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. 350 hsa-mir-200a ZEB1 Breast Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. 351 hsa-mir-200b ZEB1 Pancreatic Neoplasms 21224848 The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells. 352 hsa-mir-9-2 CDX2 Stomach Neoplasms 21225631 MiR-9 down-regulates CDX2 expression in gastric cancer cells. 353 hsa-mir-9-3 CDX2 Stomach Neoplasms 21225631 MiR-9 down-regulates CDX2 expression in gastric cancer cells. 354 hsa-mir-9-3 CDX2 Stomach Neoplasms 21225631 MiR-9 downregulates CDX2 expression in gastric cancer cells. 355 hsa-mir-9-1 CDX2 Stomach Neoplasms 21225631 MiR-9 down-regulates CDX2 expression in gastric cancer cells. 356 hsa-mir-9-1 CDX2 Stomach Neoplasms 21225631 MiR-9 downregulates CDX2 expression in gastric cancer cells. 357 hsa-mir-9-2 CDX2 Stomach Neoplasms 21225631 MiR-9 downregulates CDX2 expression in gastric cancer cells. 358 hsa-mir-340 MET Breast Neoplasms 21225860 miR-340 inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c-Met 359 hsa-mir-885 CDK2 Neuroblastoma 21233845 MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival. 360 hsa-mir-885 MCM5 Neuroblastoma 21233845 MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival. 361 hsa-mir-155 AGTR1 Pre-Eclampsia 21234519 microRNA-155 regulates angiotensin II type 1 receptor expression in umbilical vein endothelial cells from severely pre-eclamptic pregnant women. 362 hsa-mir-34a CD44 Prostatic Neoplasms 21240262 The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. 363 hsa-mir-20a BNIP2 Colorectal Neoplasms 21242194 miR-20a targets BNIP2 and contributes chemotherapeutic resistance in colorectal adenocarcinoma SW480 and SW620 cell lines. 364 hsa-mir-126 VEGFA Breast Neoplasms 21249429 Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2. 365 hsa-mir-126 PIK3R2 Breast Neoplasms 21249429 Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2. 366 hsa-mir-145 FSCN1 Prostatic Neoplasms 21258769 Restoration of miR-145 expression suppresses cell proliferation, migration and invasion in prostate cancer by targeting FSCN1. 367 hsa-mir-26b EphA2 Glioma 21264258 This study demonstrated that miR-26b may act as a tumor suppressor in glioma and it directly regulates EphA2 expression. EphA2 is a direct target of miR-26b, and the down-regulation of EphA2 mediated by miR-26b is dependent on the binding of miR-26b to a 368 hsa-mir-107 CDK6 Gastrointestinal Neoplasms 21264532 miR-107 targets cyclin-dependent kinase 6 expression, induces cell cycle G1 arrest and inhibits invasion in gastric cancer cells. 369 hsa-mir-19a TNF Esophageal Neoplasms 21271217 TNF-alpha is a novel target of miR-19a. 370 hsa-mir-381 MIT Mastocytosis, Systemic 21273305 We found that miR-539 and miR-381 are downregulated by KIT signaling and they repressed MITF expression through conserved miRNA binding sites in the MITF 3' UTR. 371 hsa-mir-539 MIT Mastocytosis, Systemic 21273305 We found that miR-539 and miR-381 are downregulated by KIT signaling and they repressed MITF expression through conserved miRNA binding sites in the MITF 3' UTR. 372 hsa-mir-221 CDKN1C Colorectal Neoplasms 21278784 MicroRNA-221 inhibits CDKN1C/p57 expression in human colorectal carcinoma. 373 hsa-mir-21 Spry2 Glioma 21278789 Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas. 374 hsa-mir-145 EGFR Lung Neoplasms 21289483 MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1. 375 hsa-mir-145 NUDT1 Lung Neoplasms 21289483 MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1. 376 hsa-mir-141 YAP1 Esophageal Neoplasms 21289630 MicroRNA-141 confers resistance to cisplatin-induced apoptosis by targeting YAP1 in human esophageal squamous cell carcinoma. 377 hsa-mir-203 p63 Esophageal Neoplasms 21299870 MicroRNA-203 inhibits cell proliferation by repressing DeltaNp63 expression in human esophageal squamous cell carcinoma. 378 hsa-mir-203 p63 Carcinoma, Squamous Cell 21299870 MicroRNA-203 inhibits cell proliferation by repressing DeltaNp63 expression in human esophageal squamous cell carcinoma. 379 hsa-mir-1-2 TAGLN2 Urinary Bladder Neoplasms 21304530 The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. 380 hsa-mir-133a-1 TAGLN2 Urinary Bladder Neoplasms 21304530 The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. 381 hsa-mir-133a-2 TAGLN2 Urinary Bladder Neoplasms 21304530 The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. 382 hsa-mir-1-1 TAGLN2 Urinary Bladder Neoplasms 21304530 The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. 383 hsa-mir-126 SOX2 Gastrointestinal Neoplasms 21304604 miR-126 is a novel miRNA that targets SOX2, and PLAC1 may be a novel downstream target gene of SOX2 in gastric cancer cells. These findings suggest that aberrant over-expression of miR-126 and consequent SOX2 down-regulation may contribute to gastric carc 384 hsa-mir-125b-1 MUC1 Prostatic Neoplasms 21308711 miR-125b suppresses MUC1 translation in LNCaP cells and that an anti-sense miR-125b upregulates expression of MUC1 protein. In addition, stable expression of miR-125b in DU145 cells resulted in decreases in MUC1 levels. 385 hsa-mir-125b-2 MUC1 Prostatic Neoplasms 21308711 miR-125b suppresses MUC1 translation in LNCaP cells and that an anti-sense miR-125b upregulates expression of MUC1 protein. In addition, stable expression of miR-125b in DU145 cells resulted in decreases in MUC1 levels. 386 hsa-mir-222 ETS1 Inflammation 21310411 HUVECs highly expressed miR-155 may co-target AT1R and Ets-1 while miR-221/222 targets Ets-1, which indirectly regulate the expression of several inflammatory molecules of ECs, and therefore attenuate the adhesion of Jurkat T cells to activated HUVECs and 387 hsa-mir-221 ETS1 Inflammation 21310411 HUVECs highly expressed miR-155 may co-target AT1R and Ets-1 while miR-221/222 targets Ets-1, which indirectly regulate the expression of several inflammatory molecules of ECs, and therefore attenuate the adhesion of Jurkat T cells to activated HUVECs and 388 hsa-mir-155 AT1R Inflammation 21310411 HUVECs highly expressed miR-155 may co-target AT1R and Ets-1 while miR-221/222 targets Ets-1, which indirectly regulate the expression of several inflammatory molecules of ECs, and therefore attenuate the adhesion of Jurkat T cells to activated HUVECs and 389 hsa-mir-155 ETS1 Inflammation 21310411 HUVECs highly expressed miR-155 may co-target AT1R and Ets-1 while miR-221/222 targets Ets-1, which indirectly regulate the expression of several inflammatory molecules of ECs, and therefore attenuate the adhesion of Jurkat T cells to activated HUVECs and 390 hsa-mir-21 ANP32A Prostatic Neoplasms 21317927 MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4 391 hsa-mir-21 SMARCA4 Prostatic Neoplasms 21317927 MicroRNA-21 targets tumor suppressor genes ANP32A and SMARCA4 392 hsa-mir-199a-2 AXL Carcinoma, Non-Small-Cell Lung 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 393 hsa-mir-199a-2 AXL Breast Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 394 hsa-mir-199a-1 AXL Carcinoma, Non-Small-Cell Lung 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 395 hsa-mir-199a-1 AXL Breast Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 396 hsa-mir-199a-2 AXL Colorectal Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 397 hsa-mir-34a AXL Colorectal Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 398 hsa-mir-199b AXL Breast Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 399 hsa-mir-199a-1 AXL Colorectal Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 400 hsa-mir-34a AXL Breast Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 401 hsa-mir-199b AXL Carcinoma, Non-Small-Cell Lung 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 402 hsa-mir-199b AXL Colorectal Neoplasms 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 403 hsa-mir-34a AXL Carcinoma, Non-Small-Cell Lung 21317930 Axl receptor expression can be regulated by miR-34a and miR-199a/b, which are suppressed by promoter methylation in solid cancer cells 404 hsa-mir-124-1 IQGAP1 Breast Neoplasms 21318219 Genetic variants (SNP rs1042538 A/T) at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. 405 hsa-mir-124-2 IQGAP1 Breast Neoplasms 21318219 Genetic variants (SNP rs1042538 A/T) at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. 406 hsa-mir-124-3 IQGAP1 Breast Neoplasms 21318219 Genetic variants (SNP rs1042538 A/T) at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. 407 hsa-mir-34c MYC Colorectal Neoplasms 21329882 MK5 regulates translation of Myc, since it is required for expression of miR-34b and miR-34c that bind to the 3'UTR of MYC. MK5 activates miR-34b/c expression via phosphorylation of FoxO3a, thereby promoting nuclear localization of FoxO3a and enabling it 408 hsa-mir-34b MYC Colorectal Neoplasms 21329882 MK5 regulates translation of Myc, since it is required for expression of miR-34b and miR-34c that bind to the 3'UTR of MYC. MK5 activates miR-34b/c expression via phosphorylation of FoxO3a, thereby promoting nuclear localization of FoxO3a and enabling it 409 hsa-let-7a-1 RAB40C Gastrointestinal Neoplasms 21349817 let-7a is significant in suppressing gastric cancer growth in vivo and in vitro and provided the first evidence that RAB40C is negatively regulated by let-7a at the post-transcriptional level via binding to the 3'-untranslated region of RAB40C mRNA in gas 410 hsa-let-7a-2 RAB40C Gastrointestinal Neoplasms 21349817 let-7a is significant in suppressing gastric cancer growth in vivo and in vitro and provided the first evidence that RAB40C is negatively regulated by let-7a at the post-transcriptional level via binding to the 3'-untranslated region of RAB40C mRNA in gas 411 hsa-let-7a-3 RAB40C Gastrointestinal Neoplasms 21349817 let-7a is significant in suppressing gastric cancer growth in vivo and in vitro and provided the first evidence that RAB40C is negatively regulated by let-7a at the post-transcriptional level via binding to the 3'-untranslated region of RAB40C mRNA in gas 412 hsa-mir-451a RAB14 Carcinoma, Non-Small-Cell Lung 21358675 MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14). 413 hsa-mir-16-1 ZYX Laryngeal Neoplasms 21360639 MicroRNA-16 targets zyxin and promotes cell motility in human laryngeal carcinoma cell line HEp-2. 414 hsa-mir-16-2 ZYX Laryngeal Neoplasms 21360639 MicroRNA-16 targets zyxin and promotes cell motility in human laryngeal carcinoma cell line HEp-2. 415 hsa-mir-145 OCT4 Adenocarcinoma 21365617 Up-regulation of microRNA-145 promotes differentiation by repressing OCT4 in human endometrial adenocarcinoma cells. 416 hsa-mir-34a E2F1 Leukemia 21367750 miR-34a induces the down-regulation of both E2F1 and B-Myb oncogenes in leukemic cells. 417 hsa-mir-34a MYB Leukemia 21367750 miR-34a induces the down-regulation of both E2F1 and B-Myb oncogenes in leukemic cells. 418 hsa-mir-1-1 TAGLN2 Head and Neck Neoplasms 21378409 miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. 419 hsa-mir-1-2 TAGLN2 Carcinoma, Squamous Cell 21378409 miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. 420 hsa-mir-1-2 TAGLN2 Head and Neck Neoplasms 21378409 miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. 421 hsa-mir-1-1 TAGLN2 Carcinoma, Squamous Cell 21378409 miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. 422 hsa-mir-9-1 JAK Glioblastoma 21385897 miR-9 suppresses mesenchymal differentiation in glioblastoma by downregulating expression of JAK kinases and inhibiting activation of STAT3. 423 hsa-mir-9-2 JAK Glioblastoma 21385897 miR-9 suppresses mesenchymal differentiation in glioblastoma by downregulating expression of JAK kinases and inhibiting activation of STAT3. 424 hsa-mir-9-3 JAK Glioblastoma 21385897 miR-9 suppresses mesenchymal differentiation in glioblastoma by downregulating expression of JAK kinases and inhibiting activation of STAT3. 425 hsa-mir-204 FOXC1 Endometrial Neoplasms 21400511 Dysregulation of microRNA-204 mediates migration and invasion of endometrial cancer by regulating FOXC1. 426 hsa-mir-125b-1 FGFR2 Psoriasis 21412257 MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2. 427 hsa-mir-125b-2 FGFR2 Psoriasis 21412257 MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2. 428 hsa-mir-204 EZR Stomach Neoplasms 21416062 MiR-204, which was predicted to target ezrin, was downregulated in gastric cancer cells and gastric carcinomas. MiR-204 inhibited ezrin expression, Ras activation, cell growth and cell migration 429 hsa-mir-204 PDEF Prostatic Neoplasms 21446014 PDEF expression is regulated via a functional microRNA-204 (miR-204) binding site within the 3'UTR. Furthermore, we demonstrate the biologic significance of miR-204 expression and that miR-204 is over-expressed in human prostate cancer specimens. 430 hsa-mir-148a BCL2 Colorectal Neoplasms 21455217 MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer. 431 hsa-mir-214 TFAP2C Melanoma 21468029 miR-214 is highly expressed in human melanomas and contributes to melanoma tumour progression through suppression of TFAP2C 432 hsa-mir-145 OCT4 Lung Neoplasms 21479367 microRNA-145 suppresses lung adenocarcinoma-initiating cell proliferation by targeting OCT4. 433 hsa-mir-373 PPP6C Carcinoma, Hepatocellular 21481188 miR-373 can regulate cell cycle progression by targeting PPP6C transcripts and promotes the growth activity of hepatocellular carcinoma cells in vitro. This miRNA functions as an oncogene in hepatocellular carcinoma. 434 hsa-mir-142 RAC1 Carcinoma, Hepatocellular 21482222 MicroRNA-142-3p, a new regulator of RAC1, suppresses the migration and invasion of hepatocellular carcinoma cells. 435 hsa-mir-221 DVL2 Prostatic Neoplasms 21487968 MiR-221 expression affects invasion potential of human prostate carcinoma cell lines by targeting DVL2. 436 hsa-mir-223 MYC Carcinoma, Hepatocellular 21492514 microRNA-223 and its target gene oncogene c-myc have roles in hepatocellular carcinoma pathogenesis. 437 hsa-mir-145 OCT4 Lung Neoplasms 21496429 miR-145 Inhibits Lung Adenocarcinoma Stem Cells Proliferation by Targeting OCT4 Gene. 438 hsa-mir-18a CTGF Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 439 hsa-mir-18b CTGF Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 440 hsa-mir-19b-1 CTGF Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 441 hsa-mir-19b-2 CTGF Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 442 hsa-mir-19a CTGF Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 443 hsa-mir-18a TSP1 Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 444 hsa-mir-18b TSP1 Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 445 hsa-mir-19b-1 TSP1 Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 446 hsa-mir-19b-2 TSP1 Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 447 hsa-mir-19a TSP1 Heart Failure 21501375 MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. 448 hsa-mir-26b SLC7A11 Breast Neoplasms 21510944 MicroRNA-26b is underexpressed in human breast cancer and induces cell apoptosis by targeting SLC7A11. 449 hsa-mir-519d MKi67 Carcinoma, Hepatocellular 21524841 MicroRNA-519d targets MKi67 and suppresses cell growth in the hepatocellular carcinoma cell line QGY-7703. 450 hsa-mir-622 ING1 Stomach Neoplasms 21528065 Down-regulation of miR-622 in gastric cancer promotes cellular invasion and tumor metastasis by targeting ING1 gene. 451 hsa-mir-200a ZEB2 Ovarian Neoplasms 21529905 MicroRNA-200a inhibits CD133/1+ ovarian cancer stem cells migration and invasion by targeting E-cadherin repressor ZEB2. 452 hsa-let-7f-1 MYH9 Stomach Neoplasms 21533124 MicroRNA Let-7f Inhibits Tumor Invasion and Metastasis by Targeting MYH9 in Human Gastric Cancer. 453 hsa-let-7f-2 MYH9 Stomach Neoplasms 21533124 MicroRNA Let-7f Inhibits Tumor Invasion and Metastasis by Targeting MYH9 in Human Gastric Cancer. 454 hsa-let-7d PBX3 Prostatic Neoplasms 21548940 PBX3 is up-regulated in prostate cancer and post- transcriptionally regulated by androgen through Let-7d. 455 hsa-mir-125b-1 BMPR1B Prostatic Neoplasms 21556765 rs1434536 in the 3'UTR of BMPR1B gene affects the binding ability of miR-125b to BMPR1B mRNA and contributes to the genetic hspredisposition to localized prostate cancer and patients aged >70years. 456 hsa-mir-125b-2 BMPR1B Prostatic Neoplasms 21556765 rs1434536 in the 3'UTR of BMPR1B gene affects the binding ability of miR-125b to BMPR1B mRNA and contributes to the genetic hspredisposition to localized prostate cancer and patients aged >70years. 457 hsa-mir-637 ATP6V0A1 Hypertension 21558123 A common genetic variant (rs938671) in the 3'-UTR of Vacuolar H+-ATPase ATP6V0A1 creates a micro-RNA (hsa-miR-637) motif to alter Chromogranin A (CHGA) processing and hypertension risk. 458 hsa-mir-342 DNMT1 Colorectal Neoplasms 21565830 MicroRNA-342 Inhibits Colorectal Cancer Cell Proliferation and Invasion by Directly Targeting DNA Methyltransferase 1. 459 hsa-mir-1302-2 CGA Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 460 hsa-mir-1302-7 CGA Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 461 hsa-mir-1302-1 CGA Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 462 hsa-mir-1302-8 CGA Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 463 hsa-mir-1302-3 CGA Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 464 hsa-mir-1302-4 CGA Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 465 hsa-mir-1302-5 CGA Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 466 hsa-mir-1302-6 CGA Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 467 hsa-mir-1302-2 CPEB1 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 468 hsa-mir-1302-7 CPEB1 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 469 hsa-mir-1302-1 CPEB1 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 470 hsa-mir-1302-8 CPEB1 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 471 hsa-mir-1302-3 CPEB1 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 472 hsa-mir-1302-4 CPEB1 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 473 hsa-mir-1302-5 CPEB1 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 474 hsa-mir-1302-6 CPEB1 Infertility, Male 21601192 Two SNPs from two genes (rs6631 of CGA and rs2303846 of CPEB1)(binding sites of miR-1302) were found to be associated with idiopathic male infertility. Functionally, the substitution of A by T in rs6631 results in decreased binding affinity of miR-1302 an 475 hsa-let-7a-1 IL13 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 476 hsa-let-7e IL13 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 477 hsa-let-7a-2 IL13 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 478 hsa-let-7d IL13 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 479 hsa-let-7f-1 IL13 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 480 hsa-let-7b IL13 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 481 hsa-let-7c IL13 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 482 hsa-let-7g IL13 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 483 hsa-let-7i IL13 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 484 hsa-let-7a-3 IL13 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 485 hsa-let-7f-2 IL13 Inflammation 21616524 Let-7 microRNAs inhibit IL-13 expression and represent a major regulatory mechanism for modulating IL-13 secretion in IL-13-producing cell types and thereby T(H)2 inflammation. 486 hsa-mir-223 EPB41L3 Stomach Neoplasms 21628394 miRNA-223 Promotes Gastric Cancer Invasion and Metastasis by Targeting Tumor Suppressor EPB41L3. 487 hsa-mir-100 RBSP3 Leukemia, Myeloid, Acute 21643017 MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia. 488 hsa-mir-372 CDK2 Uterine Cervical Neoplasms 21646351 MicroRNA-372 Is Down-regulated and Targets Cyclin-dependent Kinase 2 (CDK2) and Cyclin A1 in Human Cervical Cancer, Which May Contribute to Tumorigenesis. 489 hsa-mir-372 CCNA1 Uterine Cervical Neoplasms 21646351 MicroRNA-372 Is Down-regulated and Targets Cyclin-dependent Kinase 2 (CDK2) and Cyclin A1 in Human Cervical Cancer, Which May Contribute to Tumorigenesis. 490 hsa-mir-338 SMO Carcinoma, Hepatocellular 21671467 miR-338-3p suppresses invasion of liver cancer cell by targeting smoothened. 491 hsa-mir-192 ERCC3 Carcinoma, Hepatocellular 21672525 MiR-192 inhibits nucleotide excision repair by targeting ERCC3 and ERCC4 in HepG2.2.15 cells. 492 hsa-mir-192 ERCC4 Carcinoma, Hepatocellular 21672525 MiR-192 inhibits nucleotide excision repair by targeting ERCC3 and ERCC4 in HepG2.2.15 cells. 493 hsa-mir-124-2 ROCK2 Carcinoma, Hepatocellular 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. 494 hsa-mir-124-1 ROCK2 Carcinoma, Hepatocellular 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. 495 hsa-mir-124-3 ROCK2 Carcinoma, Hepatocellular 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. 496 hsa-mir-124-2 EZH2 Carcinoma, Hepatocellular 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. 497 hsa-mir-124-1 EZH2 Carcinoma, Hepatocellular 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. 498 hsa-mir-124-3 EZH2 Carcinoma, Hepatocellular 21672940 The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. 499 hsa-mir-340 MET Breast Neoplasms 21692045 miR-340 inhibites breast cancer cell migration and invasion through targeting of oncoprotein c-Met. 500 hsa-mir-148a CDC25B Pancreatic Neoplasms 21709669 MicroRNA-148a is down-regulated in human pancreatic ductal adenocarcinomas and regulates cell survival by targeting CDC25B. 501 hsa-mir-488 AR Prostatic Neoplasms 21710544 miR 488* inhibits androgen receptor expression in prostate carcinoma cells. 502 hsa-mir-302d CXCR4 Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. 503 hsa-mir-302a CXCR4 Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. 504 hsa-mir-302b CXCR4 Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. 505 hsa-mir-302c CXCR4 Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. 506 hsa-mir-367 CXCR4 Glioblastoma 21720384 The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. 507 hsa-mir-187 DAB2 Ovarian Neoplasms 21725366 microRNA-187 Regulates of ovarian cancer progression through targeting Disabled homolog-2. 508 hsa-mir-15b BMI1 Tongue Neoplasms 21725369 MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1. 509 hsa-mir-200b BMI1 Tongue Neoplasms 21725369 MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1. 510 hsa-mir-221 SLC25A3 Glioblastoma 21743492 miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTP mu. 511 hsa-mir-222 SLC25A3 Glioblastoma 21743492 miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTP mu. 512 hsa-mir-7-1 BCL2 Carcinoma, Non-Small-Cell Lung 21750649 MicroRNA-7 inhibits the growth of human non-small cell lung cancer A549 cells through targeting BCL-2. 513 hsa-mir-7-3 BCL2 Carcinoma, Non-Small-Cell Lung 21750649 MicroRNA-7 inhibits the growth of human non-small cell lung cancer A549 cells through targeting BCL-2. 514 hsa-mir-7-2 BCL2 Carcinoma, Non-Small-Cell Lung 21750649 MicroRNA-7 inhibits the growth of human non-small cell lung cancer A549 cells through targeting BCL-2. 515 hsa-mir-1-2 CCND2 Thyroid Neoplasms 21752897 MiR-1 suppress Thyroid Cancer by Targeting CCND2, CXCR4, and SDF-1{alpha} 516 hsa-mir-1-1 CCND2 Thyroid Neoplasms 21752897 MiR-1 suppress Thyroid Cancer by Targeting CCND2, CXCR4, and SDF-1{alpha} 517 hsa-mir-1-2 CXCR4 Thyroid Neoplasms 21752897 MiR-1 suppress Thyroid Cancer by Targeting CCND2, CXCR4, and SDF-1{alpha} 518 hsa-mir-1-1 CXCR4 Thyroid Neoplasms 21752897 MiR-1 suppress Thyroid Cancer by Targeting CCND2, CXCR4, and SDF-1{alpha} 519 hsa-mir-1-2 CXCL12 Thyroid Neoplasms 21752897 MiR-1 suppress Thyroid Cancer by Targeting CCND2, CXCR4, and SDF-1{alpha} 520 hsa-mir-1-1 CXCL12 Thyroid Neoplasms 21752897 MiR-1 suppress Thyroid Cancer by Targeting CCND2, CXCR4, and SDF-1{alpha} 521 hsa-mir-375 MTDH Carcinoma, Squamous Cell 21753766 Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC). 522 hsa-mir-29c TNFAIP3 Carcinoma, Hepatocellular 21763284 miR-29c targets TNFAIP3, inhibits cell proliferation and induces apoptosis in hepatitis B virus-related hepatocellular carcinoma. 523 hsa-mir-133a-1 COL1A1 Hypertension 21769867 MiR-133a regulates collagen 1A1, which has potential role in myocardial fibrosis in angiotensin II dependent hypertension. 524 hsa-mir-133a-2 COL1A1 Hypertension 21769867 MiR-133a regulates collagen 1A1, which has potential role in myocardial fibrosis in angiotensin II dependent hypertension. 525 hsa-mir-143 Ptgs2 Urinary Bladder Neoplasms 21790228 Expression of miR-143 Reduces Growth and Migration of Human Bladder Carcinoma Cells by Targeting Cyclooxygenase-2. 526 hsa-mir-29b-1 MMP2 Carcinoma, Hepatocellular 21793034 MicroRNA-29b suppresses tumor angiogenesis, invasion and metastasis by regulating MMP-2 expression. 527 hsa-mir-29b-2 MMP2 Carcinoma, Hepatocellular 21793034 MicroRNA-29b suppresses tumor angiogenesis, invasion and metastasis by regulating MMP-2 expression. 528 hsa-mir-218-2 RICTOR Carcinoma, Squamous Cell 21795477 The tumor suppressive microRNA miR-218 targets the mTOR component Rictor and inhibits AKT phosphorylation in oral cancer. 529 hsa-mir-218-1 RICTOR Carcinoma, Squamous Cell 21795477 The tumor suppressive microRNA miR-218 targets the mTOR component Rictor and inhibits AKT phosphorylation in oral cancer. 530 hsa-mir-19a DKK3 Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma 531 hsa-mir-19b-1 DKK3 Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma 532 hsa-mir-92a-1 DKK3 Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma 533 hsa-mir-17 DKK3 Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma 534 hsa-mir-20a DKK3 Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma 535 hsa-mir-18a DKK3 Neuroblastoma 21796614 Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma 536 hsa-mir-210 ISCU Pre-Eclampsia 21801864 miR-210 Targets Iron-Sulfur Cluster Scaffold Homologue 537 hsa-mir-199a-2 CAV2 Carcinoma, Hepatocellular 21807947 MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. 538 hsa-mir-199a-1 CAV2 Urinary Bladder Neoplasms 21807947 MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. 539 hsa-mir-199a-1 CAV2 Carcinoma, Hepatocellular 21807947 MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. 540 hsa-mir-199a-2 CAV2 Urinary Bladder Neoplasms 21807947 MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. 541 hsa-mir-367 RYR3 Breast Neoplasms 21810988 Functional SNP (rs1044129, is present in binding region) in the microRNA-367 binding site in the 3'UTR of the calcium channel ryanodine receptor gene 3 (RYR3) affects breast cancer risk and calcification. 542 hsa-mir-375 IGF1R Carcinoma, Squamous Cell 21813472 MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor. 543 hsa-mir-34a AXL Breast Neoplasms 21814748 Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA. 544 hsa-mir-106b RB Laryngeal Neoplasms 21819631 MiR-106b promotes cell proliferation via targeting RB in laryngeal carcinoma. 545 hsa-mir-335 BCL2L2 Stomach Neoplasms 21822301 MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1. 546 hsa-mir-146b MMP16 Pancreatic Neoplasms 21823013 miR-146b-5p has inhibitory effects of on cell migration and invasion of pancreatic cancer by targeting MMP16. 547 hsa-mir-125b-2 BCL2 Ovarian Neoplasms 21823019 miR-125b confers resistance of ovarian cancer cells to cisplatin by targeting pro-apoptotic Bcl-2 antagonist killer 1. 548 hsa-mir-125b-1 BCL2 Ovarian Neoplasms 21823019 miR-125b confers resistance of ovarian cancer cells to cisplatin by targeting pro-apoptotic Bcl-2 antagonist killer 1. 549 hsa-mir-21 Spry1 Prostatic Neoplasms 21826097 Spry1 is a target for miR-21-mediated gene silencing. 550 hsa-mir-451a Ywhaz Diabetic Nephropathies 21827757 MicroRNA-451 regulates p38 MAPK signaling by targeting of Ywhaz and suppresses the mesangial hypertrophy in early Diabetic Nephropathies. 551 hsa-mir-144 IRS1 Diabetes Mellitus, Type 2 21829658 MicroRNA 144 Impairs Insulin Signaling by Inhibiting the Expression of Insulin Receptor Substrate 1 in Type 2 Diabetes Mellitus. 552 hsa-mir-194-1 BMI1 Endometrial Neoplasms 21851624 MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1. 553 hsa-mir-194-2 BMI1 Endometrial Neoplasms 21851624 MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1. 554 hsa-mir-375 YAP1 Lung Neoplasms 21856745 miR-375 is activated by ASH1 and inhibits YAP1 in a lineage dependent manner in lung cancer. 555 hsa-mir-9-3 CAMTA1 Glioblastoma 21857646 CAMTA1 is a novel tumour suppressor regulated by miR-9/9(*) in glioblastoma stem cells. 556 hsa-mir-9-2 CAMTA1 Glioblastoma 21857646 CAMTA1 is a novel tumour suppressor regulated by miR-9/9(*) in glioblastoma stem cells. 557 hsa-mir-9-1 CAMTA1 Glioblastoma 21857646 CAMTA1 is a novel tumour suppressor regulated by miR-9/9(*) in glioblastoma stem cells. 558 hsa-mir-221 TRPS1 Breast Neoplasms 21868360 miR-221/222 Targeting of Trichorhinophalangeal 1 (TRPS1) Promotes Epithelial-to-Mesenchymal Transition in Breast Cancer. 559 hsa-mir-222 TRPS1 Breast Neoplasms 21868360 miR-221/222 Targeting of Trichorhinophalangeal 1 (TRPS1) Promotes Epithelial-to-Mesenchymal Transition in Breast Cancer. 560 hsa-mir-21 RhoB Colorectal Neoplasms 21872591 miR-21 targets the tumor suppressor RhoB and regulates proliferation, invasion and apoptosis in colorectal cancer cells. 561 hsa-mir-216b KRAS Nasopharyngeal Neoplasms 21878506 miR-216b suppresses tumor growth and invasion by targeting KRAS in nasopharyngeal carcinoma. 562 hsa-mir-423 p21Cip1 Carcinoma, Hepatocellular 21890460 MicroRNA-423 Promotes Cell Growth and Regulates G1/S Transition by Targeting p21Cip1/Waf1 in Hepatocellular Carcinoma 563 hsa-mir-373 mTOR Fibrosarcoma 21898400 miR-520c and miR-373 increased the expression of MMP9 by directly targeting the 3'UTRs of mRNAs of mTOR and SIRT1 and suppressing their translation; resulting in activation of the Ras/Raf/MEK/Erk signaling pathway and NF-¦ÊB; and finally increasing the mRN 564 hsa-mir-373 SIRT1 Fibrosarcoma 21898400 miR-520c and miR-373 increased the expression of MMP9 by directly targeting the 3'UTRs of mRNAs of mTOR and SIRT1 and suppressing their translation; resulting in activation of the Ras/Raf/MEK/Erk signaling pathway and NF-¦ÊB; and finally increasing the mRN 565 hsa-mir-520c mTOR Fibrosarcoma 21898400 miR-520c and miR-373 increased the expression of MMP9 by directly targeting the 3'UTRs of mRNAs of mTOR and SIRT1 and suppressing their translation; resulting in activation of the Ras/Raf/MEK/Erk signaling pathway and NF-¦ÊB; and finally increasing the mRN 566 hsa-mir-520c SIRT1 Fibrosarcoma 21898400 miR-520c and miR-373 increased the expression of MMP9 by directly targeting the 3'UTRs of mRNAs of mTOR and SIRT1 and suppressing their translation; resulting in activation of the Ras/Raf/MEK/Erk signaling pathway and NF-¦ÊB; and finally increasing the mRN 567 hsa-mir-200c ZEB1 Head and Neck Neoplasms 21899661 The expression of ZEB1, a target mRNA for miR-200c, was up-regulated 3 and 6 hours after HGF stimulation. 568 hsa-mir-200c ZEB1 Carcinoma, Squamous Cell 21899661 The expression of ZEB1, a target mRNA for miR-200c, was up-regulated 3 and 6 hours after HGF stimulation. 569 hsa-mir-27b ST14 Head and Neck Neoplasms 21899661 The expression of ST14/matriptase an enzyme for extracellular matrix (ECM) degradation and HGF activation and a target mRNA for miR-27b, was drastically up-regulated in protein level after HGF stimulation. 570 hsa-mir-27b ST14 Carcinoma, Squamous Cell 21899661 The expression of ST14/matriptase an enzyme for extracellular matrix (ECM) degradation and HGF activation and a target mRNA for miR-27b, was drastically up-regulated in protein level after HGF stimulation. 571 hsa-mir-224 DIO1 Carcinoma, Renal Cell 21912701 MiR-224 Targets the 3'UTR of Type 1 5'-Iodothyronine Deiodinase Possibly Contributing to Tissue Hypothyroidism in Renal Cancer. 572 hsa-mir-145 p70S6K1 Colonic Neoplasms 21917858 The expression of miR-145 is downregulated in colon and ovarian cancer tissues and cell lines. MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis. 573 hsa-mir-145 p70S6K1 Ovarian Neoplasms 21917858 The expression of miR-145 is downregulated in colon and ovarian cancer tissues and cell lines. MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis. 574 hsa-mir-1-1 FN1 Carcinoma, Squamous Cell 21924268 miRNA-1 targets fibronectin1 and suppresses the migration and invasion of the HEp2 laryngeal squamous carcinoma cell line. 575 hsa-mir-1-1 FN1 Laryngeal Neoplasms 21924268 miRNA-1 targets fibronectin1 and suppresses the migration and invasion of the HEp2 laryngeal squamous carcinoma cell line. 576 hsa-mir-1-2 FN1 Carcinoma, Squamous Cell 21924268 miRNA-1 targets fibronectin1 and suppresses the migration and invasion of the HEp2 laryngeal squamous carcinoma cell line. 577 hsa-mir-1-2 FN1 Laryngeal Neoplasms 21924268 miRNA-1 targets fibronectin1 and suppresses the migration and invasion of the HEp2 laryngeal squamous carcinoma cell line. 578 hsa-mir-200a Keap1 Breast Neoplasms 21926171 miR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells. 579 hsa-mir-23a MAFbx Atrophy 21926429 miR-23a suppresses the translation of both MAFbx/atrogin-1 and MuRF1 in a 3UTR-dependent manner. Ectopic expression of miR-23a is sufficient to protect muscles from atrophy in vitro and in vivo. 580 hsa-mir-23a MuRF1 Atrophy 21926429 miR-23a suppresses the translation of both MAFbx/atrogin-1 and MuRF1 in a 3UTR-dependent manner. Ectopic expression of miR-23a is sufficient to protect muscles from atrophy in vitro and in vivo. 581 hsa-mir-499a FOXO4 Colorectal Neoplasms 21934092 microRNA-499-5p promotes cellular invasion and tumor metastasis in colorectal cancer by targeting FOXO4 and PDCD4. 582 hsa-mir-499a PDCD4 Colorectal Neoplasms 21934092 microRNA-499-5p promotes cellular invasion and tumor metastasis in colorectal cancer by targeting FOXO4 and PDCD4. 583 hsa-mir-195 BCL2L2 Carcinoma, Hepatocellular 21947305 miRNA-195 sensitizes human hepatocellular carcinoma cells to 5-FU by targeting BCL-w. 584 hsa-mir-191 NDST1 Stomach Neoplasms 21947487 MicroRNA-191 targets N-deacetylase/N-sulfotransferase 1 and promotes cell growth in human gastric carcinoma cell line MGC803. 585 hsa-mir-25 TNFRSF10A Cholangiocarcinoma 21953056 miR-25 targets TRAIL death Receptor-4 and promotes apoptosis resistance in cholangiocarcinoma. 586 hsa-mir-185 DNMT3A Glioma 21962230 MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma. 587 hsa-mir-185 DNMT3B Glioma 21962230 MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma. 588 hsa-mir-125b-1 TP53INP1 Endometrial Neoplasms 21970405 MiR-125b promotes proliferation and migration of type II endometrial carcinoma cells through targeting TP53INP1 tumor suppressor in vitro and in vivo. 589 hsa-mir-125b-2 TP53INP1 Endometrial Neoplasms 21970405 MiR-125b promotes proliferation and migration of type II endometrial carcinoma cells through targeting TP53INP1 tumor suppressor in vitro and in vivo. 590 hsa-mir-608 HIL6 Sarcoma, Kaposi 21984125 We show a direct repression of vIL-6 by hsa-miR-1293 and hIL-6 by hsa-miR-608. The repression of vIL-6 by miR-1293 was reversed by disruption of the vIL-6 miR-1293 seed match through the introduction of point mutations. In addition, expression of vIL-6 or 591 hsa-mir-1293 VIL6 Sarcoma, Kaposi 21984125 We show a direct repression of vIL-6 by hsa-miR-1293 and hIL-6 by hsa-miR-608. The repression of vIL-6 by miR-1293 was reversed by disruption of the vIL-6 miR-1293 seed match through the introduction of point mutations. In addition, expression of vIL-6 or 592 hsa-let-7c MMP11 Colorectal Neoplasms 21984339 Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer. 593 hsa-let-7c PBX3 Colorectal Neoplasms 21984339 Let-7c functions as a metastasis suppressor by targeting MMP11 and PBX3 in colorectal cancer. 594 hsa-mir-200b BCL2 Stomach Neoplasms 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. 595 hsa-mir-200b BCL2 Carcinoma, Non-Small-Cell Lung 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. 596 hsa-mir-200c BCL2 Stomach Neoplasms 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. 597 hsa-mir-200c BCL2 Carcinoma, Non-Small-Cell Lung 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. 598 hsa-mir-429 BCL2 Stomach Neoplasms 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. 599 hsa-mir-429 BCL2 Carcinoma, Non-Small-Cell Lung 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. 600 hsa-mir-200b XIAP Stomach Neoplasms 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. 601 hsa-mir-200b XIAP Carcinoma, Non-Small-Cell Lung 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. 602 hsa-mir-200c XIAP Stomach Neoplasms 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. 603 hsa-mir-200c XIAP Carcinoma, Non-Small-Cell Lung 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. 604 hsa-mir-429 XIAP Stomach Neoplasms 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. 605 hsa-mir-429 XIAP Carcinoma, Non-Small-Cell Lung 21993663 miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP. 606 hsa-mir-148b CCKBR Colorectal Neoplasms 22020560 MicroRNA-148b suppresses cell growth by targeting cholecystokinin-2 receptor in colorectal cancer. 607 hsa-mir-146a SMAD4 Stomach Neoplasms 22020746 Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis. 608 hsa-mir-214 HTT Huntington Disease 22048026 Micro RNA -214,-150,-146a and-125b target Huntingtin gene. 609 hsa-mir-150 HTT Huntington Disease 22048026 Micro RNA -214,-150,-146a and-125b target Huntingtin gene. 610 hsa-mir-125b-2 HTT Huntington Disease 22048026 Micro RNA -214,-150,-146a and-125b target Huntingtin gene. 611 hsa-mir-125b-1 HTT Huntington Disease 22048026 Micro RNA -214,-150,-146a and-125b target Huntingtin gene. 612 hsa-mir-146a HTT Huntington Disease 22048026 Micro RNA -214,-150,-146a and-125b target Huntingtin gene. 613 hsa-mir-375 AEG1 Carcinoma, Hepatocellular 22056881 MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo. 614 hsa-mir-133a-2 PNP Prostatic Neoplasms 22068816 Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. 615 hsa-mir-1-2 PNP Prostatic Neoplasms 22068816 Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. 616 hsa-mir-1-1 PNP Prostatic Neoplasms 22068816 Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. 617 hsa-mir-133a-1 PNP Prostatic Neoplasms 22068816 Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. 618 hsa-mir-21 GRHL3 Carcinoma, Squamous Cell 22094257 Targeting of the Tumor Suppressor GRHL3 by a miR-21-Dependent Proto-Oncogenic Network Results in PTEN Loss and Tumorigenesis. 619 hsa-mir-21 CCL20 Colorectal Neoplasms 22099878 miR-21 functionally interacts with the 3'UTR of chemokine CCL20 and down-regulates CCL20 expression in miR-21 transfected colorectal cancer cells. 620 hsa-mir-520e NIK Carcinoma, Hepatocellular 22105365 MicroRNA-520e suppresses growth of hepatoma cells by targeting the NF-kB-inducing kinase (NIK). 621 hsa-mir-143 SERPINE1 Urinary Bladder Neoplasms 22108519 The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer. 622 hsa-mir-145 SERPINE1 Urinary Bladder Neoplasms 22108519 The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer. 623 hsa-mir-34b CCND1 Breast Neoplasms 22113133 In this study, we identified one such estrogen down-regulated microRNA, miR-34b, as an onco-suppressor that targets cyclin D1 and JAG-1 (jagged 1) in a ER-positive/wild-type p53 breast cancer cell line (MCF-7) as well as in ovarian and endometrial cells, 624 hsa-mir-34b CCND1 Breast Neoplasms 22113133 In this study, we identified one such estrogen down-regulated microRNA, miR-34b, as an onco-suppressor that targets cyclin D1 and JAG-1 (jagged 1) in a ER-positive/wild-type p53 breast cancer cell line (MCF-7) as well as in ovarian and endometrial cells, 625 hsa-mir-27b JAG1 Neuroblastoma 22120719 MiR-27b targets PPARgamma to inhibit growth, tumor progression and the inflammatory response in neuroblastoma cells. 626 hsa-mir-1915 BCL2 Colorectal Neoplasms 22121083 miR-1915 inhibits Bcl-2 to modulate multidrug resistance by increasing drug-sensitivity in human colorectal carcinoma cells. 627 hsa-mir-221 p57 Colonic Neoplasms 22126772 MicroRNA-221 promotes colon carcinoma cell proliferation in vitro by inhibiting CDKN1C/p57 expression. 628 hsa-mir-17 RND3 Colorectal Neoplasms 22132820 Up-regulated miR-17 promotes cell proliferation, tumor growth and cell cycle progression by targeting RND3 tumor suppressor gene in colorectal carcinoma. 629 hsa-mir-320a NRP1 Colorectal Neoplasms 22134529 microRNA-320a inhibits tumor invasion by targeting neuropilin 1 and is associated with liver metastasis in colorectal cancer. 630 hsa-mir-210 VMP1 Carcinoma, Hepatocellular 22144109 Hypoxia-inducible MicroRNA-210 augments the metastatic potential of tumor cells by targeting vacuole membrane protein 1 in hepatocellular carcinoma. 631 hsa-mir-200c FHOD1 Breast Neoplasms 22144583 MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F. 632 hsa-mir-200c PPM1F Breast Neoplasms 22144583 MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F. 633 hsa-mir-23b NOX4 Pain 22149086 MiR23b Ameliorates Neuropathic Pain in Spinal Cord by Silencing NOX4. 634 hsa-mir-1245a BRCA2 Breast Neoplasms 22158906 Upregulation of miR-1245 by c-myc targets BRCA2 and impairs DNA repair. 635 hsa-mir-1245b BRCA2 Breast Neoplasms 22158906 Upregulation of miR-1245 by c-myc targets BRCA2 and impairs DNA repair. 636 hsa-mir-34a MYC Carcinoma, Renal Cell 22159222 MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma. 637 hsa-mir-205 VEGFA Glioblastoma 22159356 MicroRNA-205 functions as a tumor suppressor in human glioblastoma cells by targeting VEGF-A. 638 hsa-mir-143 BCL2 Uterine Cervical Neoplasms 22160209 miR-143 is downregulated in cervical cancer and promotes apoptosis and inhibits tumor formation by targeting Bcl-2. 639 hsa-mir-137 CSMD1 Schizophrenia 22182936 Schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 are miR-137 targets. 640 hsa-mir-137 C10orf26 Schizophrenia 22182936 Schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 are miR-137 targets. 641 hsa-mir-137 CACNA1C Schizophrenia 22182936 Schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 are miR-137 targets. 642 hsa-mir-137 TCF4 Schizophrenia 22182936 Schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 are miR-137 targets. 643 hsa-mir-200c CCNE2 Lymphoma 22183793 MicroRNA-200 is commonly repressed in conjunctival MALT lymphoma, and targets cyclin E2. 644 hsa-mir-200b CCNE2 Lymphoma 22183793 MicroRNA-200 is commonly repressed in conjunctival MALT lymphoma, and targets cyclin E2. 645 hsa-mir-200a CCNE2 Lymphoma 22183793 MicroRNA-200 is commonly repressed in conjunctival MALT lymphoma, and targets cyclin E2. 646 hsa-mir-570 CD274 Stomach Neoplasms 22190470 A guanine-to-cytosine mutation at the 3'-UTR of CD274 mRNA led to CD274 over-expression by disrupting the miR-570 binding. A frequent somatic mutation in CD274 3'-UTR leads to protein over-expression in gastric cancer by disrupting miR-570 binding. 647 hsa-mir-200b TFAP2A Endometrial Neoplasms 22194984 Luciferase assays and Western blot analysis demonstrated that the miR-200b/200c/429 family recognized the MRE in the 3' UTR of AP-2alpha gene and negatively regulated the expression of endogenous AP-2alpha proteins. SNP rs1045385 A>C variation enhanced AP-2alpha. 648 hsa-mir-429 TFAP2A Endometrial Neoplasms 22194984 Luciferase assays and Western blot analysis demonstrated that the miR-200b/200c/429 family recognized the MRE in the 3' UTR of AP-2 alpha gene and negatively regulated the expression of endogenous AP-2 alpha proteins. SNP rs1045385 A>C variation enhanced AP-2 alpha expression. 649 hsa-mir-200c TFAP2A Endometrial Neoplasms 22194984 Luciferase assays and Western blot analysis demonstrated that the miR-200b/200c/429 family recognized the MRE in the 3' UTR of AP-2 alpha gene and negatively regulated the expression of endogenous AP-2 alpha proteins. SNP rs1045385 A>C variation enhanced AP-2 alpha expression. 650 hsa-mir-181d KRAS Glioma 22207524 MiR-181d acts as a tumor suppressor in glioma by targeting K-ras and Bcl-2. 651 hsa-mir-181d BCL2 Glioma 22207524 MiR-181d acts as a tumor suppressor in glioma by targeting K-ras and Bcl-2. 652 hsa-mir-34a BIRC5 Laryngeal Neoplasms 22246523 MicroRNA-34a affects the occurrence of laryngeal squamous cell carcinoma by targeting the antiapoptotic gene survivin. 653 hsa-mir-124-1 HMGA1 Medulloblastoma 22249617 hsa-miR-124a targeted 3'UTR of HMGA1 and negatively modulated the expression in MB cells. 654 hsa-let-7i RAS Pancreatic Neoplasms 22261338 The miRNAs, let-7i and miR-143 was found to target Ras, and forced re-expression of let-7i and miR-143 inhibited Ras activity, cell proliferation and colony formation in vitro. 655 hsa-mir-143 RAS Pancreatic Neoplasms 22261338 The miRNAs, let-7i and miR-143 was found to target Ras, and forced re-expression of let-7i and miR-143 inhibited Ras activity, cell proliferation and colony formation in vitro. 656 hsa-let-7f-2 IL23R Crohn Disease 22262659 The rs10889677 variant in the 3'-untranslated region of the IL-23R gene displays enhanced levels of both mRNA and protein production of IL-23R. This can be attributed to a loss of binding capacity for the microRNAs (miRNAs) Let-7e and Let-7f by the varian 657 hsa-let-7e IL23R Crohn Disease 22262659 The rs10889677 variant in the 3'-untranslated region of the IL-23R gene displays enhanced levels of both mRNA and protein production of IL-23R. This can be attributed to a loss of binding capacity for the microRNAs (miRNAs) Let-7e and Let-7f by the varian 658 hsa-let-7f-1 IL23R Crohn Disease 22262659 The rs10889677 variant in the 3'-untranslated region of the IL-23R gene displays enhanced levels of both mRNA and protein production of IL-23R. This can be attributed to a loss of binding capacity for the microRNAs (miRNAs) Let-7e and Let-7f by the varian 659 hsa-mir-195 GLUT3 Urinary Bladder Neoplasms 22265971 MicroRNA-195-5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulating GLUT3 expression. 660 hsa-mir-32 BTG2 Prostatic Neoplasms 22266859 Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer. 661 hsa-mir-21 PTEN Stomach Neoplasms 22267008 microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN. 662 hsa-mir-30a DTL Colonic Neoplasms 22287560 MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL. 663 hsa-mir-127 FCGR1A Inflammation 22287715 MicroRNA-127 Inhibits Lung Inflammation by Targeting IgG Fcgamma Receptor I. 664 hsa-mir-203 BIRC5 Laryngeal Neoplasms 22306317 MicroRNA-203 leads to G1 phase cell cycle arrest in laryngeal carcinoma cells by directly targeting survivin. 665 hsa-mir-205 PTEN Nasopharyngeal Neoplasms 22306986 MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN. 666 hsa-mir-125b-2 ARID3B Breast Neoplasms 22307404 miR-125b targets ARID3B in breast cancer cells. 667 hsa-mir-125b-1 ARID3B Breast Neoplasms 22307404 miR-125b targets ARID3B in breast cancer cells. 668 hsa-mir-135a-1 JAK2 Stomach Neoplasms 22310976 MiR-135a targets JAK2 and inhibits gastric cancer cell proliferation. 669 hsa-mir-135a-2 JAK2 Stomach Neoplasms 22310976 MiR-135a targets JAK2 and inhibits gastric cancer cell proliferation. 670 hsa-mir-520b MEKK2 Carcinoma, Hepatocellular 22319632 MicroRNA-520b inhibits growth of hepatoma cells by targeting MEKK2 and cyclin D1. 671 hsa-mir-520b CCND1 Carcinoma, Hepatocellular 22319632 MicroRNA-520b inhibits growth of hepatoma cells by targeting MEKK2 and cyclin D1. 672 hsa-mir-30c-2 HMBOX1 Carcinoma, Hepatocellular 22320217 miR-30c-1* promotes natural killer cell cytotoxicity against human hepatoma cells by targeting the transcription factor HMBOX1. 673 hsa-mir-30c-1 HMBOX1 Carcinoma, Hepatocellular 22320217 miR-30c-1* promotes natural killer cell cytotoxicity against human hepatoma cells by targeting the transcription factor HMBOX1. 674 hsa-mir-182 CREB1 Stomach Neoplasms 22325466 MicroRNA-182 targets cAMP-responsive element-binding protein 1 and suppresses cell growth in human gastric adenocarcinoma. 675 hsa-mir-195 BCL2 Breast Neoplasms 22328513 miR-195, miR-24-2 and miR-365-2 act as negative regulators of BCL2 through direct binding to their respective binding sites in the 3' UTR of human BCL2 gene.over expression of these miRNAs not only caused an increase in apoptosis but also augmented the ap 676 hsa-mir-24-2 BCL2 Breast Neoplasms 22328513 miR-195, miR-24-2 and miR-365-2 act as negative regulators of BCL2 through direct binding to their respective binding sites in the 3' UTR of human BCL2 gene.over expression of these miRNAs not only caused an increase in apoptosis but also augmented the ap 677 hsa-mir-365b BCL2 Breast Neoplasms 22328513 miR-195, miR-24-2 and miR-365-2 act as negative regulators of BCL2 through direct binding to their respective binding sites in the 3' UTR of human BCL2 gene.over expression of these miRNAs not only caused an increase in apoptosis but also augmented the ap 678 hsa-mir-29b-1 ATP1B1 Breast Neoplasms 22330642 Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly, 679 hsa-mir-513a-1 ATP1B1 Breast Neoplasms 22330642 Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly, 680 hsa-mir-29a ATP1B1 Breast Neoplasms 22330642 Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly, 681 hsa-mir-513a-2 ATP1B1 Breast Neoplasms 22330642 Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly, 682 hsa-mir-29c ATP1B1 Breast Neoplasms 22330642 Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly, 683 hsa-mir-29b-2 ATP1B1 Breast Neoplasms 22330642 Progestin treatment decreases miR-29, thereby relieving repression of one of its direct targets, the gene encoding ATPase, Na(+)/K(+) transporting, beta 1 polypeptide (ATP1B1). ATP1B1 serves to limit migration and invasion in breast cancer cells. Lastly, 684 hsa-mir-32 REV3L Lung Neoplasms 22349819 REV3L 3'UTR 460 T>C polymorphism in microRNA(miR-25/32) target sites contributes to lung cancer susceptibility. 685 hsa-mir-25 REV3L Lung Neoplasms 22349819 REV3L 3'UTR 460 T>C polymorphism in microRNA(miR-25/32) target sites contributes to lung cancer susceptibility. 686 hsa-mir-212 PTCH1 Carcinoma, Non-Small-Cell Lung 22357618 MiR-212 displays Tumor Promoting properties in NSCLC Cells and targets the Hedgehog Pathway Receptor PTCH1. 687 hsa-mir-138-2 CCND3 Carcinoma, Hepatocellular 22362728 MiR-138 induces cell cycle arrest by targeting cyclin D3 in hepatocellular carcinoma. 688 hsa-mir-138-1 CCND3 Carcinoma, Hepatocellular 22362728 MiR-138 induces cell cycle arrest by targeting cyclin D3 in hepatocellular carcinoma. 689 hsa-mir-1-1 SLUG Prostatic Neoplasms 22370643 Mir-1 and miR-200 were reduced with progression of prostate adenocarcinoma, and we identify Slug as one of the phylogenetically conserved targets of these miRs. The authors demonstrate that SLUG is a direct repressor of miR-1 and miR-200 transcription. Th 690 hsa-mir-1-2 SLUG Prostatic Neoplasms 22370643 Mir-1 and miR-200 were reduced with progression of prostate adenocarcinoma, and we identify Slug as one of the phylogenetically conserved targets of these miRs. The authors demonstrate that SLUG is a direct repressor of miR-1 and miR-200 transcription. Th 691 hsa-mir-200b SLUG Prostatic Neoplasms 22370643 Mir-1 and miR-200 were reduced with progression of prostate adenocarcinoma, and we identify Slug as one of the phylogenetically conserved targets of these miRs. The authors demonstrate that SLUG is a direct repressor of miR-1 and miR-200 transcription. Th 692 hsa-mir-200a SLUG Prostatic Neoplasms 22370643 Mir-1 and miR-200 were reduced with progression of prostate adenocarcinoma, and we identify Slug as one of the phylogenetically conserved targets of these miRs. The authors demonstrate that SLUG is a direct repressor of miR-1 and miR-200 transcription. Th 693 hsa-mir-200c SLUG Prostatic Neoplasms 22370643 Mir-1 and miR-200 were reduced with progression of prostate adenocarcinoma, and we identify Slug as one of the phylogenetically conserved targets of these miRs. The authors demonstrate that SLUG is a direct repressor of miR-1 and miR-200 transcription. Th 694 hsa-mir-199b PODXL Leukemia, Myeloid, Acute 22374871 miR-199b-5p directly targets PODXL and DDR1 and decreased levels of miR-199b-5p correlate with elevated expressions of PODXL and DDR1 in acute myeloid leukemia. 695 hsa-mir-199b DDR1 Leukemia, Myeloid, Acute 22374871 miR-199b-5p directly targets PODXL and DDR1 and decreased levels of miR-199b-5p correlate with elevated expressions of PODXL and DDR1 in acute myeloid leukemia. 696 hsa-mir-18a THBS1 Hemangiosarcoma 22383169 The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. 697 hsa-mir-19a THBS1 Hemangiosarcoma 22383169 The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. 698 hsa-mir-20a THBS1 Hemangiosarcoma 22383169 The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. 699 hsa-mir-17 THBS1 Hemangiosarcoma 22383169 The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. 700 hsa-mir-92a-1 THBS1 Hemangiosarcoma 22383169 The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. 701 hsa-mir-19b-1 THBS1 Hemangiosarcoma 22383169 The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. 702 hsa-mir-409 PHF10 Stomach Neoplasms 22388101 MicroRNA-409-3p regulates cell proliferation and apoptosis by targeting PHF10 in gastric cancer. 703 hsa-mir-328 IGF1R Hypertension 22392900 The MicroRNA-328 Regulates Hypoxic Pulmonary Hypertension by Targeting at Insulin Growth Factor 1 Receptor and L-Type Calcium Channel-alpha1C. 704 hsa-mir-328 CACNA1C Hypertension 22392900 The MicroRNA-328 Regulates Hypoxic Pulmonary Hypertension by Targeting at Insulin Growth Factor 1 Receptor and L-Type Calcium Channel-alpha1C. 705 hsa-mir-133b EGFR Prostatic Neoplasms 22407299 microRNA-133 inhibits cell proliferation, migration and invasion in prostate cancer cells by targeting the epidermal growth factor receptor. 706 hsa-mir-133a-2 EGFR Prostatic Neoplasms 22407299 microRNA-133 inhibits cell proliferation, migration and invasion in prostate cancer cells by targeting the epidermal growth factor receptor. 707 hsa-mir-133a-1 EGFR Prostatic Neoplasms 22407299 microRNA-133 inhibits cell proliferation, migration and invasion in prostate cancer cells by targeting the epidermal growth factor receptor. 708 hsa-mir-200c ZEB1 Colorectal Neoplasms 22407310 miR-200c inhibits invasion and migration in human colon cancer cells SW480/620 by targeting ZEB1.miR-200c inhibits metastatic ability by targeting ZEB1 in colon cancer cells SW480/620 and suggested that modulation of miR-200c could serve as therapeutic to 709 hsa-mir-125b-1 MAZ Glioblastoma 22415301 Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma. 710 hsa-mir-125b-2 MAZ Glioblastoma 22415301 Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma. 711 hsa-mir-20a EPHB4 Pre-Eclampsia 22438230 Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta. 712 hsa-mir-20a EFNB2 Pre-Eclampsia 22438230 Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta. 713 hsa-mir-20b EPHB4 Pre-Eclampsia 22438230 Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta. 714 hsa-mir-20b EFNB2 Pre-Eclampsia 22438230 Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta. 715 hsa-mir-17 EPHB4 Pre-Eclampsia 22438230 Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta. 716 hsa-mir-17 EFNB2 Pre-Eclampsia 22438230 Preeclampsia Up-Regulates Angiogenesis-Associated MicroRNA (i.e., miR-17, -20a, and -20b) That Target Ephrin-B2 and EPHB4 in Human Placenta. 717 hsa-mir-135a-1 HOXA10 Breast Neoplasms 22439757 miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10. 718 hsa-mir-135a-2 HOXA10 Breast Neoplasms 22439757 miRNA-135a promotes breast cancer cell migration and invasion by targeting HOXA10. 719 hsa-mir-128-2 p70S6K1 Glioma 22442669 miR-128 expression levels were decreased in glioma. MiR-128 Inhibits Tumor Growth and Angiogenesis by Targeting p70S6K1. 720 hsa-mir-128-1 p70S6K1 Glioma 22442669 miR-128 expression levels were decreased in glioma. MiR-128 Inhibits Tumor Growth and Angiogenesis by Targeting p70S6K1. 721 hsa-mir-219-1 GPC3 Carcinoma, Hepatocellular 22449976 MiR-219-5p inhibits hepatocellular carcinoma cell proliferation by targeting glypican-3. 722 hsa-mir-219-2 GPC3 Carcinoma, Hepatocellular 22449976 MiR-219-5p inhibits hepatocellular carcinoma cell proliferation by targeting glypican-3. 723 hsa-mir-20a TNKS2 Uterine Cervical Neoplasms 22449978 miR-20a promotes migration and invasion by regulating TNKS2 in human cervical cancer cells. 724 hsa-mir-23a MTSS Colorectal Neoplasms 22455847 MiR-23a expression promotes colon carcinoma cell growth, invasion and metastasis through inhibition of MTSS gene. 725 hsa-mir-320a CTNNB1 Colorectal Neoplasms 22459450 MicroRNA-320a suppresses human colon cancer cell proliferation by directly targeting beta-catenin. 726 hsa-mir-125b-1 ERBB2 Endometrial Neoplasms 22460089 MicroRNA-125b down-regulation mediates endometrial cancer invasion by targeting ERBB2. 727 hsa-mir-125b-2 ERBB2 Endometrial Neoplasms 22460089 MicroRNA-125b down-regulation mediates endometrial cancer invasion by targeting ERBB2. 728 hsa-mir-21 SERPINI1 Stomach Neoplasms 22464652 MicroRNA-21 inhibits Serpini1, a gene with novel tumour suppressive effects in gastric cancer. 729 hsa-mir-483 ERK1 Glioma 22465663 MiR-483-5p suppresses the proliferation of glioma cells via directly targeting ERK1. 730 hsa-mir-551a PRL3 Stomach Neoplasms 22469786 MiR-495 and miR-551a inhibit the migration and invasion of human gastric cancer cells by directly interacting with PRL-3. 731 hsa-mir-495 PRL3 Stomach Neoplasms 22469786 MiR-495 and miR-551a inhibit the migration and invasion of human gastric cancer cells by directly interacting with PRL-3. 732 hsa-mir-155 GABRR1 Glioblastoma 22470130 miR-155 is up-regulated in primary and secondary glioblastoma and promotes tumour growth by inhibiting GABA receptors. 733 hsa-mir-145 EGFR Osteosarcoma 22472569 MicroRNA-145 targets vascular endothelial growth factor and inhibits invasion and metastasis of osteosarcoma cells. 734 hsa-mir-34a PDGFRA Glioma 22479456 miR-34a Repression in Proneural Malignant Gliomas Upregulates Expression of Its Target PDGFRA and Promotes Tumorigenesis. 735 hsa-mir-141 PPARA Hepatitis B 22479552 MicroRNA-141 Represses HBV Replication by Targeting PPARA 736 hsa-mir-22 ERBB3 Lung Neoplasms 22484852 miR-22 suppresses lung cancer cell progression through post-transcriptional regulation of ErbB3. 737 hsa-mir-183 EZR Osteosarcoma 22525461 Down-regulation of miR-183 promotes migration and invasion of osteosarcoma by targeting Ezrin. 738 hsa-mir-143 MACC1 Colorectal Neoplasms 22533346 MicroRNA-143 targets MACC1 to inhibit cell invasion and migration in colorectal cancer. 739 hsa-mir-181b-2 CREB1 Stomach Neoplasms 22539488 MicroRNA-181b targets cAMP responsive element binding protein 1 in gastric adenocarcinomas. 740 hsa-mir-181b-1 CREB1 Stomach Neoplasms 22539488 MicroRNA-181b targets cAMP responsive element binding protein 1 in gastric adenocarcinomas. 741 hsa-mir-214 TWIST Cholangiocarcinoma 22540680 Downregulated miR-214 contributes to intrahepatic cholangiocarcinoma metastasis by targeting Twist. 742 hsa-mir-27a ZBTB10 Breast Neoplasms 22553354 Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer. 743 hsa-mir-19a CUL5 Uterine Cervical Neoplasms 22561557 MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5. 744 hsa-mir-19b-2 CUL5 Uterine Cervical Neoplasms 22561557 MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5. 745 hsa-mir-19b-1 CUL5 Uterine Cervical Neoplasms 22561557 MicroRNA-19a and -19b regulate cervical carcinoma cell proliferation and invasion by targeting CUL5. 746 hsa-mir-9-2 MMP14 Neuroblastoma 22564723 microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells. 747 hsa-mir-9-1 MMP14 Neuroblastoma 22564723 microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells. 748 hsa-mir-9-3 MMP14 Neuroblastoma 22564723 microRNA-9 targets matrix metalloproteinase 14 to inhibit invasion, metastasis, and angiogenesis of neuroblastoma cells. 749 hsa-mir-10b SDC1 Breast Neoplasms 22573479 Targeting of syndecan-1 by microRNA miR-10b promotes breast cancer cell motility and invasiveness via a Rho-GTPase- and E-cadherin-dependent mechanism. 750 hsa-mir-139 IGF1R Colorectal Neoplasms 22580051 MiR-139 inhibits invasion and metastasis of colorectal cancer by targeting the type I insulin-like growth factor receptor. 751 hsa-mir-181a-2 KLF6 Stomach Neoplasms 22581522 MicroRNA-181a promotes gastric cancer by negatively regulating tumor suppressor KLF6. 752 hsa-mir-181a-1 KLF6 Stomach Neoplasms 22581522 MicroRNA-181a promotes gastric cancer by negatively regulating tumor suppressor KLF6. 753 hsa-mir-381 ID1 Lung Neoplasms 22592211 MicroRNA-381 represses ID1 and is deregulated in lung adenocarcinoma. 754 hsa-mir-103a-1 DAPK Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 755 hsa-mir-103b-1 DAPK Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 756 hsa-mir-103a-2 DAPK Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 757 hsa-mir-103b-2 DAPK Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 758 hsa-mir-107 DAPK Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 759 hsa-mir-103a-1 KLF4 Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 760 hsa-mir-103b-1 KLF4 Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 761 hsa-mir-103a-2 KLF4 Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 762 hsa-mir-103b-2 KLF4 Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 763 hsa-mir-107 KLF4 Colorectal Neoplasms 22593189 miR-103/107 Promote Metastasis of Colorectal Cancer by Targeting the Metastasis Suppressors DAPK and KLF4. 764 hsa-mir-101-2 EZH2 Carcinoma, Renal Cell 22609199 The enhancer of zeste homolog 2 (EZH2), a potential therapeutic target, is regulated by miR-101 in renal cancer cells. 765 hsa-mir-101-1 EZH2 Carcinoma, Renal Cell 22609199 The enhancer of zeste homolog 2 (EZH2), a potential therapeutic target, is regulated by miR-101 in renal cancer cells. 766 hsa-mir-10a CHL1 Uterine Cervical Neoplasms 22634495 MicroRNA-10a targets CHL1 and promotes cell growth, migration and invasion in human cervical cancer cells. 767 hsa-mir-139 RAP1B Colorectal Neoplasms 22642900 Regulation of RAP1B by miR-139 suppresses human colorectal carcinoma cell proliferation. 768 hsa-mir-23b TAB2 Inflammation 22660635 The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-a. 769 hsa-mir-23b TAB3 Inflammation 22660635 The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-a. 770 hsa-mir-23b CHUK Inflammation 22660635 The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-a. 771 hsa-mir-499a ETS1 Carcinoma, Hepatocellular 22664953 MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells. 772 hsa-mir-1-2 ETS1 Carcinoma, Hepatocellular 22664953 MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells. 773 hsa-mir-1-1 ETS1 Carcinoma, Hepatocellular 22664953 MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells. 774 hsa-mir-499b ETS1 Carcinoma, Hepatocellular 22664953 MicroRNA-1 and microRNA-499 downregulate the expression of the ets1 proto-oncogene in HepG2 cells. 775 hsa-mir-34a Notch1 Glioma 22684560 MicroRNA-34a inhibits human brain glioma cell growth by down-regulation of Notch1. 776 hsa-mir-34a Notch1 Urinary Bladder Neoplasms 22684561 microRNA-34a inhibit cell migration and invasion of invasive urothelial bladder carcinoma by targeting Notch1. 777 hsa-mir-590 TGFBR2 Carcinoma, Hepatocellular 22684895 MicroRNA-590-5p regulates proliferation and invasion in human hepatocellular carcinoma cells by targeting TGF-beta RII. 778 hsa-mir-200c ZEB1 Leiomyoma 22685266 miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5. 779 hsa-mir-200c ZEB2 Leiomyoma 22685266 miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5. 780 hsa-mir-200c BEGFA Leiomyoma 22685266 miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5. 781 hsa-mir-200c TIMP2 Leiomyoma 22685266 miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5. 782 hsa-mir-200c FBLN5 Leiomyoma 22685266 miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5. 783 hsa-mir-143 GCK Colonic Neoplasms 22691140 microRNA-143 down-regulates Hexokinase 2 in colon cancer cells. 784 hsa-mir-125b-1 STARD13 Breast Neoplasms 22693547 MicroRNA-125b induces metastasis by targeting STARD13 in MCF-7 and MDA-MB-231 breast cancer cells. 785 hsa-mir-125b-2 STARD13 Breast Neoplasms 22693547 MicroRNA-125b induces metastasis by targeting STARD13 in MCF-7 and MDA-MB-231 breast cancer cells. 786 hsa-mir-30c-2 KRAS Breast Neoplasms 22701724 miR-30c overexpression inhibited proliferation of breast cancer cells.miR-30c binds the 3'UTR of KRAS transcripts and expression of pre-miR-30c down-regulated KRAS mRNA and protein. 787 hsa-mir-30c-1 KRAS Breast Neoplasms 22701724 miR-30c overexpression inhibited proliferation of breast cancer cells.miR-30c binds the 3'UTR of KRAS transcripts and expression of pre-miR-30c down-regulated KRAS mRNA and protein. 788 hsa-mir-7-1 HoxB3 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. 789 hsa-mir-218-1 HoxB3 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. 790 hsa-mir-7-2 HoxB3 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. 791 hsa-mir-7-3 HoxB3 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. 792 hsa-mir-218-2 HoxB3 Breast Neoplasms 22705304 miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer. 793 hsa-mir-23b PRDX3 Prostatic Neoplasms 22710126 MicroRNA-23b downregulates peroxiredoxin III in human prostate cancer. 794 hsa-mir-497 IGF1R Colorectal Neoplasms 22710713 MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer. 795 hsa-mir-632 DNAJB6 Breast Neoplasms 22710984 Micro-RNA-632 downregulates DNAJB6 in breast cancer. 796 hsa-mir-203 BIRC5 Breast Neoplasms 22713668 MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells. 797 hsa-mir-203 LASP1 Breast Neoplasms 22713668 MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells. 798 hsa-mir-195 BACE1 Alzheimer Disease 22721728 MicroRNA-195 downregulates Alzheimer's disease amyloid-beta production by targeting BACE1. 799 hsa-mir-137 ESRRA Breast Neoplasms 22723937 MiR-137 targets estrogen-related receptor alpha and impairs the proliferative and migratory capacity of breast cancer cells. 800 hsa-mir-337 STAT3 Carcinoma, Non-Small-Cell Lung 22723956 miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers. 801 hsa-mir-337 RAP1A Carcinoma, Non-Small-Cell Lung 22723956 miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers. 802 hsa-mir-17 TP53INP1 Uterine Cervical Neoplasms 22730212 MiR-17-5p targets TP53INP1 and regulates cell proliferation and apoptosis of cervical cancer cells. 803 hsa-mir-138-1 CCND1 Nasopharyngeal Neoplasms 22739938 MiR-138 suppressed nasopharyngeal carcinoma growth and tumorigenesis by targeting the CCND1 oncogene. 804 hsa-mir-138-2 CCND1 Nasopharyngeal Neoplasms 22739938 MiR-138 suppressed nasopharyngeal carcinoma growth and tumorigenesis by targeting the CCND1 oncogene. 805 hsa-mir-513a-1 GSTP1 Lung Neoplasms 22749944 miR-513a-3p sensitizes human lung adenocarcinoma cells to chemotherapy by targeting GSTP1. 806 hsa-mir-513a-2 GSTP1 Lung Neoplasms 22749944 miR-513a-3p sensitizes human lung adenocarcinoma cells to chemotherapy by targeting GSTP1. 807 hsa-mir-138-1 VIM Carcinoma, Renal Cell 22766839 Tumor suppressive microRNA-138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma. 808 hsa-mir-138-2 VIM Carcinoma, Renal Cell 22766839 Tumor suppressive microRNA-138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma. 809 hsa-mir-218-2 LEF1 Glioblastoma 22766851 MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1. 810 hsa-mir-218-1 LEF1 Glioblastoma 22766851 MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1. 811 hsa-mir-7-1 HOXB5 Urinary Bladder Neoplasms 22768238 A microRNA-7 binding site polymorphism (1010A/G) in HOXB5 leads to differential gene expression in bladder cancer. 812 hsa-mir-7-2 HOXB5 Urinary Bladder Neoplasms 22768238 A microRNA-7 binding site polymorphism (1010A/G) in HOXB5 leads to differential gene expression in bladder cancer. 813 hsa-mir-7-3 HOXB5 Urinary Bladder Neoplasms 22768238 A microRNA-7 binding site polymorphism (1010A/G) in HOXB5 leads to differential gene expression in bladder cancer. 814 hsa-mir-125a MMP11 Carcinoma, Hepatocellular 22768249 Ectopic expression of MiR-125a inhibits the proliferation and metastasis of hepatocellular carcinoma by targeting MMP11 and VEGF. 815 hsa-mir-125a VEGFA Carcinoma, Hepatocellular 22768249 Ectopic expression of MiR-125a inhibits the proliferation and metastasis of hepatocellular carcinoma by targeting MMP11 and VEGF. 816 hsa-mir-21 PTEN Cholangiocarcinoma 22770403 PTEN and PDCD4 are bona fide targets of microRNA-21 in human cholangiocarcinoma. 817 hsa-mir-21 PDCD4 Cholangiocarcinoma 22770403 PTEN and PDCD4 are bona fide targets of microRNA-21 in human cholangiocarcinoma. 818 hsa-mir-125b-1 JUN Melanoma 22797068 MicroRNA miR-125b controls melanoma progression by direct regulation of c-Jun protein expression. 819 hsa-mir-125b-2 JUN Melanoma 22797068 MicroRNA miR-125b controls melanoma progression by direct regulation of c-Jun protein expression. 820 hsa-mir-193b PLAU Prostatic Neoplasms 22797075 CFTR suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer. 821 hsa-mir-224 PLAU Breast Neoplasms 22809510 MicroRNA-224 targets RKIP to control cell invasion and expression of metastasis genes in human breast cancer cells. 822 hsa-mir-1231 RKIP Carcinoma, Hepatocellular 22824466 A miR-1231 binding site polymorphism (rs17875871) in the 3'UTR of IFNAR1 is associated with hepatocellular carcinoma susceptibility. 823 hsa-mir-10b RKIP Breast Neoplasms 22847191 MicroRNA-10b targets E-cadherin and modulates breast cancer metastasis. 824 hsa-mir-31 RhoA Mouth Neoplasms 22854067 Passenger strand miRNA miR-31* regulates the phenotypes of oral cancer cells by targeting RhoA. 825 hsa-mir-196a-1 RAP1A Esophageal Neoplasms 22859270 MiR-196a binding-site SNP (rs6573) regulates RAP1A expression contributing to esophageal squamous cell carcinoma risk and metastasis. 826 hsa-mir-196a-2 RAP1A Esophageal Neoplasms 22859270 MiR-196a binding-site SNP (rs6573) regulates RAP1A expression contributing to esophageal squamous cell carcinoma risk and metastasis. 827 hsa-mir-29b-2 C1QTNF6 Breast Neoplasms 22864815 Three mRNAs (C1QTNF6, SPARC, and COL4A2) that are down-regulated by microRNA-29b and promote invasion ability in the breast cancer cell line MCF-7. 828 hsa-mir-29b-1 C1QTNF6 Breast Neoplasms 22864815 Three mRNAs (C1QTNF6, SPARC, and COL4A2) that are down-regulated by microRNA-29b and promote invasion ability in the breast cancer cell line MCF-7. 829 hsa-mir-29b-2 SPARC Breast Neoplasms 22864815 Three mRNAs (C1QTNF6, SPARC, and COL4A2) that are down-regulated by microRNA-29b and promote invasion ability in the breast cancer cell line MCF-7. 830 hsa-mir-29b-1 SPARC Breast Neoplasms 22864815 Three mRNAs (C1QTNF6, SPARC, and COL4A2) that are down-regulated by microRNA-29b and promote invasion ability in the breast cancer cell line MCF-7. 831 hsa-mir-29b-2 COL4A2 Breast Neoplasms 22864815 Three mRNAs (C1QTNF6, SPARC, and COL4A2) that are down-regulated by microRNA-29b and promote invasion ability in the breast cancer cell line MCF-7. 832 hsa-mir-29b-1 COL4A2 Breast Neoplasms 22864815 Three mRNAs (C1QTNF6, SPARC, and COL4A2) that are down-regulated by microRNA-29b and promote invasion ability in the breast cancer cell line MCF-7. 833 hsa-mir-502 SET8 Ovarian Neoplasms 22867998 A polymorphism (rs16917496) at the miR-502 binding site in the 3' untranslated region of the SET8 gene is associated with the risk of epithelial ovarian cancer. 834 hsa-mir-145 NEDD9 Glioblastoma 22869051 NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma. 835 hsa-mir-542 JAG1 Glioma 22871495 The Putative Tumor Suppressor miR-524-5p Directly Targets Jagged-1 and Hes-1 in Glioma. 836 hsa-mir-7-3 FAK Breast Neoplasms 22876288 MicroRNA-7 Inhibits Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer Cells via Targeting FAK Expression. 837 hsa-mir-7-2 FAK Breast Neoplasms 22876288 MicroRNA-7 Inhibits Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer Cells via Targeting FAK Expression. 838 hsa-mir-7-1 FAK Breast Neoplasms 22876288 MicroRNA-7 Inhibits Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer Cells via Targeting FAK Expression. 839 hsa-mir-196a-1 HOXA5 Carcinoma, Non-Small-Cell Lung 22876840 MicroRNA-196a promotes non-small cell lung cancer cell proliferation and invasion through targeting HOXA5. 840 hsa-mir-196a-2 HOXA5 Carcinoma, Non-Small-Cell Lung 22876840 MicroRNA-196a promotes non-small cell lung cancer cell proliferation and invasion through targeting HOXA5. 841 hsa-mir-137 ZNF804A Schizophrenia 22883350 Candidate schizophrenia gene ZNF804A is a target for hsa-miR-137. 842 hsa-mir-133b EGFR Carcinoma, Non-Small-Cell Lung 22883469 MicroRNA-133b Inhibits the Growth of Non-small Cell Lung Cancer by Targeting the Epidermal Growth Factor Receptor. 843 hsa-mir-26a-2 PTEN Lung Neoplasms 22885155 MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN. 844 hsa-mir-26a-1 PTEN Lung Neoplasms 22885155 MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN. 845 hsa-mir-203 BIRC5 Carcinoma, Hepatocellular 22886454 miR-203 inhibits proliferation of hepatocellular carcinoma cells by targeting survivin. 846 hsa-mir-335 RB1 Meningioma 22886530 miR-335 promotes cell proliferation by directly targeting Rb1 in meningiomas. 847 hsa-mir-195 LATS2 Carcinoma, Hepatocellular 22888524 MiR-195 regulates cell apoptosis of human hepatocellular carcinoma cells by targeting LATS2. 848 hsa-mir-132 TMEM106B Dementia 22895706 TMEM106B, the Risk Gene for Frontotemporal Dementia, Is Regulated by the microRNA-132/212 Cluster and Affects Progranulin Pathways. 849 hsa-mir-212 TMEM106B Dementia 22895706 TMEM106B, the Risk Gene for Frontotemporal Dementia, Is Regulated by the microRNA-132/212 Cluster and Affects Progranulin Pathways. 850 hsa-mir-370 FoxM1 Leukemia, Myeloid, Acute 22900969 The tumor suppressive role of miRNA-370 by targeting FoxM1 in acute myeloid leukemia. 851 hsa-mir-193a YY1 Endometrial Neoplasms 22907428 YY1 overexpression was found to be a consequence of miR-193a-5p downregulation through direct miR-193a-5p-YY1 interplay. 852 hsa-mir-642a DOHH Prostatic Neoplasms 22908221 Regulation of expression of deoxyhypusine hydroxylase (DOHH), the enzyme that catalyzes the activation of eIF5A, by miR-331-3p and miR-642-5p in prostate cancer cells. 853 hsa-mir-642b DOHH Prostatic Neoplasms 22908221 Regulation of expression of deoxyhypusine hydroxylase (DOHH), the enzyme that catalyzes the activation of eIF5A, by miR-331-3p and miR-642-5p in prostate cancer cells. 854 hsa-mir-331 DOHH Prostatic Neoplasms 22908221 Regulation of expression of deoxyhypusine hydroxylase (DOHH), the enzyme that catalyzes the activation of eIF5A, by miR-331-3p and miR-642-5p in prostate cancer cells. 855 hsa-mir-128-2 CSF1 Ovarian Neoplasms 22909061 Both miR-128 and miR-152 down-regulate CSF-1 mRNA and protein expression in ovarian cancer cells leading to decreased cell motility and adhesion in vitro, two major aspects of the metastatic potential of cancer cells. 856 hsa-mir-128-1 CSF1 Ovarian Neoplasms 22909061 Both miR-128 and miR-152 down-regulate CSF-1 mRNA and protein expression in ovarian cancer cells leading to decreased cell motility and adhesion in vitro, two major aspects of the metastatic potential of cancer cells. 857 hsa-mir-106a TGFBR2 Colorectal Neoplasms 22912877 MiR-106a inhibits the expression of transforming growth factor-beta receptor 2 (TGFBR2), leading to increased CRC cell migration and invasion. Importantly, miR-106a expression levels in primary CRCs are correlated with clinical cancer progression. 858 hsa-mir-10b MICB Neoplasms 22915757 MiR-10b downregulates the stress-induced cell surface molecule MICB, a critical ligand for cancer cell recognition by natural killer cells. 859 hsa-mir-141 SOX17 Esophageal Neoplasms 22921431 Inhibition of SOX17 by MicroRNA-141 and Methylation Activates the WNT Signaling Pathway in Esophageal Cancer. 860 hsa-mir-183 EZR Osteosarcoma 22922800 miR-183 inhibits the metastasis of osteosarcoma via downregulation of the expression of Ezrin in F5M2 cells. 861 hsa-mir-16-1 CCND1 Osteosarcoma 22922827 miR-15a and miR-16-1 downregulate CCND1 and induce apoptosis and cell cycle arrest in osteosarcoma. 862 hsa-mir-15a CCND1 Osteosarcoma 22922827 miR-15a and miR-16-1 downregulate CCND1 and induce apoptosis and cell cycle arrest in osteosarcoma. 863 hsa-mir-155 AGTR1 Heart Failure 22939041 Angiotensin Receptor Type 1 Single Nucleotide Polymorphism 1166A/C is Associated With Malignant Arrhythmias and Altered Circulating miR-155 Levels in Patients With Chronic Heart Failure. 864 hsa-mir-124-2 PIK3CA Carcinoma, Hepatocellular 22940133 MiR-124 suppresses cell proliferation in hepatocellular carcinoma by targeting PIK3CA. 865 hsa-mir-124-1 PIK3CA Carcinoma, Hepatocellular 22940133 MiR-124 suppresses cell proliferation in hepatocellular carcinoma by targeting PIK3CA. 866 hsa-mir-203 LASP1 Esophageal Neoplasms 22940702 miR-203 inhibits the migration and invasion of esophageal squamous cell carcinoma by regulating LASP1. 867 hsa-mir-338 CCND1 Hepatitis B 22942717 miR-338-3p Is Down-Regulated by Hepatitis B Virus X and Inhibits Cell Proliferation by Targeting the 3'-UTR Region of CyclinD1. 868 hsa-mir-155 BCL6 Atherosclerosis 23041630 MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages 869 hsa-mir-141 KEAP1 Ovarian Neoplasms 23045278 miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells 870 hsa-mir-145 OCT4 Breast Neoplasms 23049906 MiR-145 regulates epithelial to mesenchymal transition of breast cancer cells by targeting Oct4 871 hsa-mir-1280 ROCK1 Urinary Bladder Neoplasms 23056431 MicroRNA-1280 inhibits invasion and metastasis by targeting ROCK1 in bladder cancer 872 hsa-mir-122 IGF1R Breast Neoplasms 23056576 MiR-122 inhibits cell proliferation and tumorigenesis of breast cancer by targeting IGF1R 873 hsa-mir-20a p21 Leukemia, Myeloid 23059786 HIF-1a downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation 874 hsa-mir-20a STAT3 Leukemia, Myeloid 23059786 HIF-1a downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation 875 hsa-mir-17 p21 Leukemia, Myeloid 23059786 HIF-1a downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation 876 hsa-mir-17 STAT3 Leukemia, Myeloid 23059786 HIF-1a downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation 877 hsa-mir-153-2 PTEN Prostatic Neoplasms 23060044 Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer 878 hsa-mir-153-1 PTEN Prostatic Neoplasms 23060044 Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer 879 hsa-mir-214 CTNNB1 Carcinoma, Hepatocellular 23068095 MiR-214 inhibits cell growth in hepatocellular carcinoma through suppression of beta-catenin 880 hsa-mir-124-3 AR Prostatic Neoplasms 23069658 Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells 881 hsa-mir-124-2 AR Prostatic Neoplasms 23069658 Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells 882 hsa-mir-124-1 AR Prostatic Neoplasms 23069658 Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells 883 hsa-mir-511-2 TRIB2 Lung Neoplasms 23071539 miR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2 884 hsa-mir-511-1 TRIB2 Lung Neoplasms 23071539 miR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2 885 hsa-mir-1297 TRIB2 Lung Neoplasms 23071539 miR-511 and miR-1297 inhibit human lung adenocarcinoma cell proliferation by targeting oncogene TRIB2 886 hsa-mir-101-1 STMN1 Breast Neoplasms 23071542 MiR-101 is involved in human breast carcinogenesis by targeting Stathmin1 887 hsa-mir-101-2 STMN1 Breast Neoplasms 23071542 MiR-101 is involved in human breast carcinogenesis by targeting Stathmin1 888 hsa-mir-125a SIRT7 Carcinoma, Hepatocellular 23079745 SIRT7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors mir-125a-5p and mir-125b 889 hsa-mir-125b-2 SIRT7 Carcinoma, Hepatocellular 23079745 SIRT7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors mir-125a-5p and mir-125b 890 hsa-mir-125b-1 SIRT7 Carcinoma, Hepatocellular 23079745 SIRT7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors mir-125a-5p and mir-125b 891 hsa-mir-34a Notch1 Breast Neoplasms 23085450 MicroRNA-34a modulates chemosensitivity of breast cancer cells to adriamycin by targeting Notch1 892 hsa-mir-26a-1 E2F7 Leukemia, Myeloid, Acute 23096114 The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells 893 hsa-mir-26a-2 E2F7 Leukemia, Myeloid, Acute 23096114 The microRNA-26a target E2F7 sustains cell proliferation and inhibits monocytic differentiation of acute myeloid leukemia cells 894 hsa-mir-15a VEGF Multiple Myeloma 23104180 miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF 895 hsa-mir-16-1 VEGF Multiple Myeloma 23104180 miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF 896 hsa-mir-16-2 VEGF Multiple Myeloma 23104180 miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF 897 hsa-mir-429 SOX2 Colorectal Neoplasms 23111103 MiR-429 is an independent prognostic factor in colorectal cancer and exerts its anti-apoptotic function by targeting SOX2 898 hsa-mir-29b-2 RNASEL Leukemia, Myeloid, Chronic-Phase 23113544 Regulation of Human RNase-L by the miR-29 Family Reveals a Novel Oncogenic Role in Chronic Myelogenous Leukemia 899 hsa-mir-29b-1 RNASEL Leukemia, Myeloid, Chronic-Phase 23113544 Regulation of Human RNase-L by the miR-29 Family Reveals a Novel Oncogenic Role in Chronic Myelogenous Leukemia 900 hsa-mir-29a RNASEL Leukemia, Myeloid, Chronic-Phase 23113544 Regulation of Human RNase-L by the miR-29 Family Reveals a Novel Oncogenic Role in Chronic Myelogenous Leukemia 901 hsa-mir-144 PTEN Nasopharyngeal Neoplasms 23125220 MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN 902 hsa-mir-205 LRRK2 Parkinson Disease 23125283 MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein 903 hsa-mir-197 CTNNB1 Pancreatic Neoplasms 23139153 MiR-197 induces epithelial-mesenchymal transition in pancreatic cancer cells by targeting p120 catenin 904 hsa-mir-1-2 SLUG Lung Neoplasms 23142026 MicroRNA-1 targets Slug and endows lung cancer A549 cells with epithelial and anti-tumorigenic properties 905 hsa-mir-1-1 SLUG Lung Neoplasms 23142026 MicroRNA-1 targets Slug and endows lung cancer A549 cells with epithelial and anti-tumorigenic properties 906 hsa-mir-149 ZBTB2 Stomach Neoplasms 23144691 MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer 907 hsa-mir-550a-2 CPEB4 Carcinoma, Hepatocellular 23145039 MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic polyadenylation element-binding protein 4 in hepatocellular carcinoma 908 hsa-mir-550a-3 CPEB4 Carcinoma, Hepatocellular 23145039 MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic polyadenylation element-binding protein 4 in hepatocellular carcinoma 909 hsa-mir-550a-1 CPEB4 Carcinoma, Hepatocellular 23145039 MicroRNA-550a acts as a pro-metastatic gene and directly targets cytoplasmic polyadenylation element-binding protein 4 in hepatocellular carcinoma 910 hsa-mir-100 PLK1 Lung Neoplasms 23151088 MicroRNA-100 is a potential molecular marker of non-small cell lung cancer and functions as a tumor suppressor by targeting polo-like kinase 1 911 hsa-mir-204 BCL2 Stomach Neoplasms 23152059 miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer 912 hsa-mir-182 NAMPT HIV-1 23153509 Down-regulation of NAMPT expression by miR-182 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation 913 hsa-mir-218-2 LAMA3 Neoplasms, Squamous Cell 23159910 Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma 914 hsa-mir-218-1 LAMA3 Neoplasms, Squamous Cell 23159910 Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma 915 hsa-mir-125b-2 PIK3CD Uterine Cervical Neoplasms 23160634 MiR-125b Inhibits Tumor Growth and Promotes Apoptosis of Cervical Cancer Cells by Targeting Phosphoinositide 3-Kinase Catalytic Subunit Delta 916 hsa-mir-125b-1 PIK3CD Uterine Cervical Neoplasms 23160634 MiR-125b Inhibits Tumor Growth and Promotes Apoptosis of Cervical Cancer Cells by Targeting Phosphoinositide 3-Kinase Catalytic Subunit Delta 917 hsa-mir-195 FASN Osteosarcoma 23162665 microRNA-195 suppresses osteosarcoma cell invasion and migration in vitro by targeting FASN 918 hsa-mir-135a-1 MYC Carcinoma, Renal Cell 23176581 Tumor-suppressive microRNA-135a inhibits cancer cell proliferation by targeting the c-MYC oncogene in renal cell carcinoma 919 hsa-mir-135a-2 MYC Carcinoma, Renal Cell 23176581 Tumor-suppressive microRNA-135a inhibits cancer cell proliferation by targeting the c-MYC oncogene in renal cell carcinoma 920 hsa-mir-137 CDC42 Lung Neoplasms 23178712 miR-137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6 921 hsa-mir-137 CDK6 Lung Neoplasms 23178712 miR-137 inhibits the proliferation of lung cancer cells by targeting Cdc42 and Cdk6 922 hsa-mir-137 YB1 Neoplasms 23178914 miR-137 restoration sensitizes multidrug-resistant MCF-7/ADM cells to anticancer agents by targeting YB-1 923 hsa-mir-367 AKT1 Uterine Cervical Neoplasms 23185040 The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1 924 hsa-mir-302a AKT1 Uterine Cervical Neoplasms 23185040 The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1 925 hsa-mir-133b EGFR Urinary Bladder Neoplasms 23206218 MicroRNA-133 inhibits cell proliferation, migration and invasion by targeting epidermal growth factor receptor and its downstream effector proteins in bladder cancer 926 hsa-mir-133a-1 EGFR Urinary Bladder Neoplasms 23206218 MicroRNA-133 inhibits cell proliferation, migration and invasion by targeting epidermal growth factor receptor and its downstream effector proteins in bladder cancer 927 hsa-mir-133a-2 EGFR Urinary Bladder Neoplasms 23206218 MicroRNA-133 inhibits cell proliferation, migration and invasion by targeting epidermal growth factor receptor and its downstream effector proteins in bladder cancer 928 hsa-mir-7-3 IRS2 Melanoma 23206698 miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling 929 hsa-mir-7-2 IRS2 Melanoma 23206698 miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling 930 hsa-mir-7-1 IRS2 Melanoma 23206698 miR-7-5p may represent a novel tumor suppressor miRNA in melanoma, acting at least in part via its inhibition of IRS-2 expression and oncogenic Akt signaling 931 hsa-mir-21 TCF21 Carcinoma, Renal Cell 23206776 miR-21 Downregulated TCF21 to Inhibit KISS1 in Renal Cancer 932 hsa-mir-7-3 YY1 Colorectal Neoplasms 23208495 microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis 933 hsa-mir-7-1 YY1 Colorectal Neoplasms 23208495 microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis 934 hsa-mir-7-2 YY1 Colorectal Neoplasms 23208495 microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis 935 hsa-mir-16-1 Ptgs2 Carcinoma, Hepatocellular 23226427 Cyclooxygenase-2 Is a Target of MicroRNA-16 in Human Hepatoma Cells 936 hsa-mir-16-2 Ptgs2 Carcinoma, Hepatocellular 23226427 Cyclooxygenase-2 Is a Target of MicroRNA-16 in Human Hepatoma Cells 937 hsa-mir-182 SMAD4 Urinary Bladder Neoplasms 23226455 Oncogenic miRNA-182-5p Targets Smad4 and RECK in Human Bladder Cancer 938 hsa-mir-182 RECK Urinary Bladder Neoplasms 23226455 Oncogenic miRNA-182-5p Targets Smad4 and RECK in Human Bladder Cancer 939 hsa-mir-21 PTEN Carcinoma, Endometrioid 23226804 microRNA-21 overexpression contributes to cell proliferation by targeting PTEN in endometrioid endometrial cancer 940 hsa-mir-383 PRDX3 Medulloblastoma 23227829 MiR-383 is Downregulated in Medulloblastoma and Targets Peroxiredoxin 3 (PRDX3) 941 hsa-mir-335 BIRC5 Lung Neoplasms 23232114 Genetic variation in a miR-335 binding site in BIRC5 alters susceptibility to lung cancer in Chinese Han populations 942 hsa-mir-596 LGALS3BP Mouth Neoplasms 23233740 Potential of tumor-suppressive miR-596 targeting LGALS3BP as a therapeutic agent in oral cancer 943 hsa-mir-372 TNFAIP1 Stomach Neoplasms 23242208 microRNA-372 maintains oncogene characteristics by targeting TNFAIP1 and affects NFkB signaling in human gastric carcinoma cells 944 hsa-mir-17 P130 Colorectal Neoplasms 23250421 Elevated oncofoetal miR-17-5p expression regulates colorectal cancer progression by repressing its target gene P130 945 hsa-mir-218-1 BMI1 Colonic Neoplasms 23255074 MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating oncogene BMI-1 946 hsa-mir-218-2 BMI1 Colonic Neoplasms 23255074 MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating oncogene BMI-1 947 hsa-mir-491 MMP9 Cerebral Infarction 23257658 A functional polymorphism at miR-491-5p binding site in the 3'-UTR of MMP-9 gene confers increased risk for atherosclerotic cerebral infarction in a Chinese population 948 hsa-mir-501 HBXIP Hepatitis B 23266610 MicroRNA-501 promotes HBV replication by targeting HBXIP 949 hsa-mir-100 mTOR Urinary Bladder Neoplasms 23270926 MicroRNA-100 inhibits human bladder urothelial carcinogenesis by directly targeting mTOR 950 hsa-mir-885 CASP3 Head and Neck Neoplasms 23271051 A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer 951 hsa-mir-362 E2F1 Colorectal Neoplasms 23280316 MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer 952 hsa-mir-362 USF2 Colorectal Neoplasms 23280316 MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer 953 hsa-mir-362 PTPN1 Colorectal Neoplasms 23280316 MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer 954 hsa-mir-99a mTOR Esophageal Neoplasms 23292834 MicroRNA-99a/100 promotes apoptosis by targeting mTOR in human esophageal squamous cell carcinoma 955 hsa-mir-100 mTOR Esophageal Neoplasms 23292834 MicroRNA-99a/100 promotes apoptosis by targeting mTOR in human esophageal squamous cell carcinoma 956 hsa-mir-196b MYC Endometriosis 23293219 miR-196b targets c-myc and Bcl-2 expression, inhibits proliferation and induces apoptosis in endometriotic stromal cells 957 hsa-mir-196b BCL2 Endometriosis 23293219 miR-196b targets c-myc and Bcl-2 expression, inhibits proliferation and induces apoptosis in endometriotic stromal cells 958 hsa-mir-133b FGFR1 Stomach Neoplasms 23296701 miR-133b acts as a tumor suppressor and negatively regulates FGFR1 in gastric cancer 959 hsa-mir-199b HER2 Breast Neoplasms 23296799 MiR-199b-5p targets HER2 in breast cancer cells 960 hsa-mir-182 PDCD4 Ovarian Neoplasms 23296900 MicroRNA-182 promotes cell growth, invasion and chemoresistance by targeting programmed cell death 4 (PDCD4) in human ovarian carcinomas 961 hsa-mir-34b SMAD3 Pancreatic Neoplasms 23305226 MicroRNA-34b inhibits pancreatic cancer metastasis through repressing Smad3 962 hsa-mir-330 CDC42 Colorectal Neoplasms 23337504 miR-330 regulates the proliferation of colorectal cancer cells by targeting Cdc42 963 hsa-mir-301a RUNX3 Stomach Neoplasms 23338485 Overexpressed miR-301a promotes cell proliferation and invasion by targeting RUNX3 in gastric cancer 964 hsa-mir-138-1 EZH2 Lung Neoplasms 23343715 MiR-138 Inhibits Tumor Growth Through Repression of EZH2 in Non-Small Cell Lung Cancer 965 hsa-mir-138-2 EZH2 Lung Neoplasms 23343715 MiR-138 Inhibits Tumor Growth Through Repression of EZH2 in Non-Small Cell Lung Cancer 966 hsa-mir-206 CCND2 Stomach Neoplasms 23348698 MiR-206 inhibits gastric cancer proliferation in part by repressing CyclinD2 967 hsa-mir-30a PRDM1 Glioma 23348703 PRDM1 is directly targeted by miR-30a-5p and modulates the Wnt/beta-catenin pathway in a Dkk1-dependent manner during glioma growth 968 hsa-mir-26b PTGS2 Breast Neoplasms 23374284 MiRNA-26b inhibits proliferation by targeting PTGS2 in breast cancer 969 hsa-mir-195 CCND1 Glioma 23383003 MicroRNA-195 Inhibits the Proliferation of Human Glioma Cells by Directly Targeting Cyclin D1 and Cyclin E1 970 hsa-mir-195 CCNE1 Glioma 23383003 MicroRNA-195 Inhibits the Proliferation of Human Glioma Cells by Directly Targeting Cyclin D1 and Cyclin E1 971 hsa-mir-30a SEPT7 Glioma 23383034 MiR-30a-5p Antisense Oligonucleotide Suppresses Glioma Cell Growth by Targeting SEPT7 972 hsa-mir-182 FOXF2 Prostatic Neoplasms 23383207 MicroRNA-182-5p Promotes Cell Invasion and Proliferation by Down Regulating FOXF2, RECK and MTSS1 Genes in Human Prostate Cancer 973 hsa-mir-182 RECK Prostatic Neoplasms 23383207 MicroRNA-182-5p Promotes Cell Invasion and Proliferation by Down Regulating FOXF2, RECK and MTSS1 Genes in Human Prostate Cancer 974 hsa-mir-182 MTSS1 Prostatic Neoplasms 23383207 MicroRNA-182-5p Promotes Cell Invasion and Proliferation by Down Regulating FOXF2, RECK and MTSS1 Genes in Human Prostate Cancer 975 hsa-mir-9-1 CCND1 Stomach Neoplasms 23383271 microRNA-9 Suppresses the Proliferation, Invasion and Metastasis of Gastric Cancer Cells through Targeting Cyclin D1 and Ets1 976 hsa-mir-9-1 ETS1 Stomach Neoplasms 23383271 microRNA-9 Suppresses the Proliferation, Invasion and Metastasis of Gastric Cancer Cells through Targeting Cyclin D1 and Ets1 977 hsa-mir-9-2 CCND1 Stomach Neoplasms 23383271 microRNA-9 Suppresses the Proliferation, Invasion and Metastasis of Gastric Cancer Cells through Targeting Cyclin D1 and Ets1 978 hsa-mir-9-2 ETS1 Stomach Neoplasms 23383271 microRNA-9 Suppresses the Proliferation, Invasion and Metastasis of Gastric Cancer Cells through Targeting Cyclin D1 and Ets1 979 hsa-mir-9-3 CCND1 Stomach Neoplasms 23383271 microRNA-9 Suppresses the Proliferation, Invasion and Metastasis of Gastric Cancer Cells through Targeting Cyclin D1 and Ets1 980 hsa-mir-9-3 ETS1 Stomach Neoplasms 23383271 microRNA-9 Suppresses the Proliferation, Invasion and Metastasis of Gastric Cancer Cells through Targeting Cyclin D1 and Ets1 981 hsa-mir-138-1 SOX4 Ovarian Neoplasms 23389731 MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1a 982 hsa-mir-138-2 SOX4 Ovarian Neoplasms 23389731 MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1a 983 hsa-mir-138-1 HIF1A Ovarian Neoplasms 23389731 MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1a 984 hsa-mir-138-2 HIF1A Ovarian Neoplasms 23389731 MicroRNA-138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF-1a 985 hsa-mir-145 SOCS7 Urinary Bladder Neoplasms 23392170 socs7, a target gene of microRNA-145, regulates interferon-alpha induction through STAT3 nuclear translocation in bladder cancer cells 986 hsa-mir-367 RYR3 Colorectal Neoplasms 23393343 the functional variant (rs1044129) in the miR-367 binding site of RYR3 may be a potential marker for prognosis in patients following curative surgery for CRC 987 hsa-mir-224 p21 Inflammatory Bowel Diseases 23399735 MicroRNA-224 Negatively Regulates p21 Expression During Late Neoplastic Progression in Inflammatory Bowel Disease 988 hsa-mir-137 KDM1A Neuroblastoma 23400681 miR-137 directly targets KDM1A mRNA in neuroblastoma cells, and activates cell properties consistent with tumor suppression 989 hsa-mir-140 TGFBR1 Carcinoma, Hepatocellular 23401231 MicroRNA-140-5p suppresses tumor growth and metastasis by targeting TGFBR1 and FGF9 in hepatocellular carcinoma 990 hsa-mir-140 FGF9 Carcinoma, Hepatocellular 23401231 MicroRNA-140-5p suppresses tumor growth and metastasis by targeting TGFBR1 and FGF9 in hepatocellular carcinoma 991 hsa-mir-151b CCNE1 Nasopharyngeal Neoplasms 23416081 A miR-151 binding site polymorphism in the 3'-untranslated region of the cyclin E1 gene associated with nasopharyngeal carcinoma 992 hsa-mir-151a CCNE1 Nasopharyngeal Neoplasms 23416081 A miR-151 binding site polymorphism in the 3'-untranslated region of the cyclin E1 gene associated with nasopharyngeal carcinoma 993 hsa-mir-17 PTEN Carcinoma, Hepatocellular 23418359 Mature MiR-17-5p and passenger miR-17-3p induce hepatocellular carcinoma by targeting PTEN, GalNT7, and vimentin in different signal pathways 994 hsa-mir-17 GalNT7 Carcinoma, Hepatocellular 23418359 Mature MiR-17-5p and passenger miR-17-3p induce hepatocellular carcinoma by targeting PTEN, GalNT7, and vimentin in different signal pathways 995 hsa-mir-17 VIM Carcinoma, Hepatocellular 23418359 Mature MiR-17-5p and passenger miR-17-3p induce hepatocellular carcinoma by targeting PTEN, GalNT7, and vimentin in different signal pathways 996 hsa-mir-24-1 PTPN9 Neoplasms 23418360 MicroRNA miR-24 Enhances Tumor Invasion and Metastasis by Targeting PTPN9 and PTPRF to Promote EGF Signaling 997 hsa-mir-24-2 PTPN9 Neoplasms 23418360 MicroRNA miR-24 Enhances Tumor Invasion and Metastasis by Targeting PTPN9 and PTPRF to Promote EGF Signaling 998 hsa-mir-24-1 PTPRF Neoplasms 23418360 MicroRNA miR-24 Enhances Tumor Invasion and Metastasis by Targeting PTPN9 and PTPRF to Promote EGF Signaling 999 hsa-mir-24-2 PTPRF Neoplasms 23418360 MicroRNA miR-24 Enhances Tumor Invasion and Metastasis by Targeting PTPN9 and PTPRF to Promote EGF Signaling 1000 hsa-mir-320d-2 RTA Sarcoma, Kaposi 23418466 Cellular MicroRNAs 498 and 320d Regulate Herpes Simplex Virus 1 Induction of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by Targeting RTA 1001 hsa-mir-320d-1 RTA Sarcoma, Kaposi 23418466 Cellular MicroRNAs 498 and 320d Regulate Herpes Simplex Virus 1 Induction of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by Targeting RTA 1002 hsa-mir-498 RTA Sarcoma, Kaposi 23418466 Cellular MicroRNAs 498 and 320d Regulate Herpes Simplex Virus 1 Induction of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by Targeting RTA 1003 hsa-mir-570 B7H1 Stomach Neoplasms 23430453 A miR-570 binding site polymorphism in the B7-H1 gene is associated with the risk of gastric adenocarcinoma 1004 hsa-mir-146a WASF2 Stomach Neoplasms 23435376 MicroRNA-146a acts as a metastasis suppressor in gastric cancer by targeting WASF2 1005 hsa-mir-126 ADAM9 Melanoma 23437250 miR-126&126* Restored Expressions Play a Tumor Suppressor Role by Directly Regulating ADAM9 and MMP7 in Melanoma 1006 hsa-mir-126 MMP7 Melanoma 23437250 miR-126&126* Restored Expressions Play a Tumor Suppressor Role by Directly Regulating ADAM9 and MMP7 in Melanoma 1007 hsa-mir-135a-2 PTK2 Neoplasms 23438844 MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells 1008 hsa-mir-138-1 PTK2 Neoplasms 23438844 MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells 1009 hsa-mir-135a-1 PTK2 Neoplasms 23438844 MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells 1010 hsa-mir-138-2 PTK2 Neoplasms 23438844 MiR-138 and MiR-135 Directly Target Focal Adhesion Kinase, Inhibit Cell Invasion, and Increase Sensitivity to Chemotherapy in Cancer Cells 1011 hsa-mir-145 ADAM17 Carcinoma, Renal Cell 23441135 MicroRNA-145 Targets the Metalloprotease ADAM17 and Is Suppressed in Renal Cell Carcinoma Patients 1012 hsa-mir-29c RCC2 Stomach Neoplasms 23442884 MiR-29c is downregulated in gastric carcinomas and regulates cell proliferation by targeting RCC2 1013 hsa-mir-497 IGF1R Uterine Cervical Neoplasms 23453369 MicroRNA-497 is a potential prognostic marker in human cervical cancer and functions as a tumor suppressor by targeting the insulin-like growth factor 1 receptor 1014 hsa-mir-218-2 CAV2 Carcinoma, Renal Cell 23454155 microRNA-218 inhibits cell migration and invasion in renal cell carcinoma through targeting caveolin-2 involved in focal adhesion pathway 1015 hsa-mir-218-1 CAV2 Carcinoma, Renal Cell 23454155 microRNA-218 inhibits cell migration and invasion in renal cell carcinoma through targeting caveolin-2 involved in focal adhesion pathway 1016 hsa-mir-146a PRKCE Thyroid Neoplasms 23457043 MicroRNA-146a targets PRKCE to modulate papillary thyroid tumor development 1017 hsa-mir-145 ERG Prostate Neoplasms 23480797 The proto-oncogene ERG is a target of microRNA miR-145 in prostate cancer 1018 hsa-mir-145 HDAC2 Carcinoma, Hepatocellular 23499894 MiR-145 functions as a tumor suppressor by directly targeting histone deacetylase 2 in liver cancer 1019 hsa-mir-16-1 IGF1R Osteosarcoma 23507142 miR-16 inhibits cell proliferation by targeting IGF1R and the Raf1-MEK1/2-ERK1/2 pathway in osteosarcoma 1020 hsa-mir-16-2 IGF1R Osteosarcoma 23507142 miR-16 inhibits cell proliferation by targeting IGF1R and the Raf1-MEK1/2-ERK1/2 pathway in osteosarcoma 1021 hsa-mir-128-2 Bax Breast Neoplasms 23526655 Downregulation of miRNA-128 sensitizes breast cancer cell to chemodrugs by targeting Bax 1022 hsa-mir-128-1 Bax Breast Neoplasms 23526655 Downregulation of miRNA-128 sensitizes breast cancer cell to chemodrugs by targeting Bax 1023 hsa-mir-22 SP1 Stomach Neoplasms 23529765 miR-22 is down-regulated in gastric cancer, and its overexpression inhibits cell migration and invasion via targeting transcription factor Sp1 1024 hsa-mir-9-3 ITGB1 Breast Neoplasms 23530058 miR-9-3p targets integrin beta 1 to sensitize claudin-low breast cancer cells to MEK inhibition 1025 hsa-mir-9-2 ITGB1 Breast Neoplasms 23530058 miR-9-3p targets integrin beta 1 to sensitize claudin-low breast cancer cells to MEK inhibition 1026 hsa-mir-9-1 ITGB1 Breast Neoplasms 23530058 miR-9-3p targets integrin beta 1 to sensitize claudin-low breast cancer cells to MEK inhibition 1027 hsa-mir-183 DKK3 Prostate Neoplasms 23538390 microRNA-183 is an oncogene targeting Dkk-3 and SMAD4 in prostate cancer 1028 hsa-mir-183 SMAD4 Prostate Neoplasms 23538390 microRNA-183 is an oncogene targeting Dkk-3 and SMAD4 in prostate cancer 1029 hsa-mir-200b CREB1 Glioma 23543137 MicroRNA-200b targets CREB1 and suppresses cell growth in human malignant glioma 1030 hsa-mir-139 MCL1 Glioma 23551751 MiR-139 Inhibits Mcl-1 Expression and Potentiates TMZ-Induced Apoptosis in Glioma 1031 hsa-mir-148a ROCK1 Carcinoma, Non-Small-Cell Lung 23670799 MicroRNA-148a suppresses epithelial-to-mesenchymal transition by targeting ROCK1 in non-small cell lung cancer cells. 1032 hsa-mir-497 HDGF Carcinoma, Non-Small-Cell Lung 23673296 Downregulation of miR-497 promotes tumor growth and angiogenesis by targeting HDGF in non-small cell lung cancer. 1033 hsa-mir-150 IGF1R Pancreatic Neoplasms 23675407 Upregulation of miR-150* and miR-630 Induces Apoptosis in Pancreatic Cancer Cells by Targeting IGF-1R. 1034 hsa-mir-630 IGF1R Pancreatic Neoplasms 23675407 Upregulation of miR-150* and miR-630 Induces Apoptosis in Pancreatic Cancer Cells by Targeting IGF-1R. 1035 hsa-mir-192-2 SOX4 Esophageal Neoplasms 23677061 miR-129-2 suppresses proliferation and migration of esophageal carcinoma cells through downregulation of SOX4 expression. 1036 hsa-mir-339 PRL1 Colorectal Neoplasms 23696794 MiR-339-5p Regulates the Growth, Colony Formation and Metastasis of Colorectal Cancer Cells by Targeting PRL-1. 1037 hsa-mir-146a STAT1 Hepatitis B 23698745 MicroRNA-146a Feedback Suppresses T Cell Immune Function by Targeting Stat1 in Patients with Chronic Hepatitis B. 1038 hsa-mir-137 RTVP1 Glioblastoma 23714687 MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1. 1039 hsa-mir-135b CD133 Lung Neoplasms 23715500 A microRNA-135a/b binding polymorphism in CD133 confers decreased risk and favorable prognosis of lung cancer in Chinese by reducing CD133 expression. 1040 hsa-mir-135a-2 CD133 Lung Neoplasms 23715500 A microRNA-135a/b binding polymorphism in CD133 confers decreased risk and favorable prognosis of lung cancer in Chinese by reducing CD133 expression. 1041 hsa-mir-135a-1 CD133 Lung Neoplasms 23715500 A microRNA-135a/b binding polymorphism in CD133 confers decreased risk and favorable prognosis of lung cancer in Chinese by reducing CD133 expression. 1042 hsa-mir-155 MLH1 Pancreatic Neoplasms 23715647 MLH1 as a Direct Target of MiR-155 and a Potential Predictor of Favorable Prognosis in Pancreatic Cancer. 1043 hsa-mir-7-2 SET8 Breast Neoplasms 23720754 MicroRNA-7 Suppresses the Invasive Potential of Breast Cancer Cells and Sensitizes Cells to DNA Damages by Targeting Histone Methyltransferase SET8. 1044 hsa-mir-7-3 SET8 Breast Neoplasms 23720754 MicroRNA-7 Suppresses the Invasive Potential of Breast Cancer Cells and Sensitizes Cells to DNA Damages by Targeting Histone Methyltransferase SET8. 1045 hsa-mir-7-1 SET8 Breast Neoplasms 23720754 MicroRNA-7 Suppresses the Invasive Potential of Breast Cancer Cells and Sensitizes Cells to DNA Damages by Targeting Histone Methyltransferase SET8. 1046 hsa-mir-370 FOXO1 Stomach Neoplasms 23721824 Upregulation of miR-370 contributes to the progression of gastric carcinoma via suppression of FOXO1. 1047 hsa-mir-133a-2 RFFL Colorectal Neoplasms 23723074 MiR-133a activates the p53/p21 pathway and functions as a tumor suppressor in colorectal cancer by repressing RFFL. 1048 hsa-mir-133a-1 RFFL Colorectal Neoplasms 23723074 MiR-133a activates the p53/p21 pathway and functions as a tumor suppressor in colorectal cancer by repressing RFFL. 1049 hsa-mir-211 TGFBR2 Head and Neck Neoplasms 23726841 miR-211 promotes the progression of head and neck carcinomas by targeting TGFbeta R2. 1050 hsa-mir-29c SIRT1 Carcinoma, Hepatocellular 23728341 MicroRNA-29c functions as a tumor suppressor by direct targeting oncogenic SIRT1 in hepatocellular carcinoma. 1051 hsa-mir-203 BIRC5 Pancreatic Neoplasms 23732815 miR-203 regulates the proliferation, apoptosis and cell cycle progression of pancreatic cancer cells by targeting Survivin. 1052 hsa-mir-451a IKBKB Carcinoma, Hepatocellular 23740840 miR-451 Inhibits Cell Proliferation in Human Hepatocellular Carcinoma through Direct Suppression of IKK-beta 1053 hsa-mir-181c CD163 PRRSV Infection 23740977 MicroRNA-181 suppresses PRRSV infection by targeting its receptor CD163. 1054 hsa-mir-181b-2 CD163 PRRSV Infection 23740977 MicroRNA-181 suppresses PRRSV infection by targeting its receptor CD163. 1055 hsa-mir-181b-1 CD163 PRRSV Infection 23740977 MicroRNA-181 suppresses PRRSV infection by targeting its receptor CD163. 1056 hsa-mir-181a-2 CD163 PRRSV Infection 23740977 MicroRNA-181 suppresses PRRSV infection by targeting its receptor CD163. 1057 hsa-mir-181a-1 CD163 PRRSV Infection 23740977 MicroRNA-181 suppresses PRRSV infection by targeting its receptor CD163. 1058 hsa-mir-7-1 XIAP Uterine Cervical Neoplasms 23742934 MicroRNA-7 downregulates XIAP expression to suppress cell growth and promote apoptosis in cervical cancer cells. 1059 hsa-mir-7-3 XIAP Uterine Cervical Neoplasms 23742934 MicroRNA-7 downregulates XIAP expression to suppress cell growth and promote apoptosis in cervical cancer cells. 1060 hsa-mir-7-2 XIAP Uterine Cervical Neoplasms 23742934 MicroRNA-7 downregulates XIAP expression to suppress cell growth and promote apoptosis in cervical cancer cells. 1061 hsa-mir-126 CXCR4 Colonic Neoplasms 23744532 Expression of miR-126 suppresses migration and invasion of colon cancer cells by targeting CXCR4. 1062 hsa-mir-150 P53 Lung Neoplasms 23747308 miR-150 promotes the proliferation of lung cancer cells by targeting P53. 1063 hsa-mir-26a-2 MCL1 Breast Neoplasms 23750239 MiR-26a Inhibits Proliferation and Migration of Breast Cancer through Repression of MCL-1. 1064 hsa-mir-26a-1 MCL1 Breast Neoplasms 23750239 MiR-26a Inhibits Proliferation and Migration of Breast Cancer through Repression of MCL-1. 1065 hsa-mir-133a-1 BCL2L1 Osteosarcoma 23756231 microRNA-133a, downregulated in osteosarcoma, suppresses proliferation and promotes apoptosis by targeting Bcl-xL and Mcl-1. 1066 hsa-mir-133a-2 BCL2L1 Osteosarcoma 23756231 microRNA-133a, downregulated in osteosarcoma, suppresses proliferation and promotes apoptosis by targeting Bcl-xL and Mcl-1. 1067 hsa-mir-133a-1 MCL1 Osteosarcoma 23756231 microRNA-133a, downregulated in osteosarcoma, suppresses proliferation and promotes apoptosis by targeting Bcl-xL and Mcl-1. 1068 hsa-mir-133a-2 MCL1 Osteosarcoma 23756231 microRNA-133a, downregulated in osteosarcoma, suppresses proliferation and promotes apoptosis by targeting Bcl-xL and Mcl-1. 1069 hsa-mir-223 PARP1 Barrett Esophagus 23757351 MicroRNA 223 is Up-regulated in the Multistep Progression of Barrett's Esophagus and Modulates Sensitivity to Chemotherapy by Targeting PARP1. 1070 hsa-mir-199a-2 SIRT1 HCMV Infection 23760629 MiR-199a-5p promotes migration and tube formation of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and eNOS. 1071 hsa-mir-199a-1 SIRT1 HCMV Infection 23760629 MiR-199a-5p promotes migration and tube formation of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and eNOS. 1072 hsa-mir-199a-2 NOS3 HCMV Infection 23760629 MiR-199a-5p promotes migration and tube formation of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and eNOS. 1073 hsa-mir-199a-1 NOS3 HCMV Infection 23760629 MiR-199a-5p promotes migration and tube formation of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and eNOS. 1074 hsa-mir-124-2 CDK4 Glioma 23761023 miR-124 radiosensitizes human glioma cells by targeting CDK4. 1075 hsa-mir-124-1 CDK4 Glioma 23761023 miR-124 radiosensitizes human glioma cells by targeting CDK4. 1076 hsa-mir-149 FOXM1 Carcinoma, Non-Small-Cell Lung 23762558 miR-149 Inhibits Non-Small-Cell Lung Cancer Cells EMT by Targeting FOXM1. 1077 hsa-mir-17 CCND1 Breast Neoplasms 18695042 A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. 1078 hsa-mir-20a CCND1 Breast Neoplasms 18695042 A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. 1079 hsa-mir-146b MMP16 Glioma 19265686 microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs. 1080 hsa-mir-101-1 EZH2 Stomach Neoplasms 20712078 miR-101-3p: MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion 1081 hsa-mir-101-2 EZH2 Stomach Neoplasms 20712078 miR-101-3p: MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion 1082 hsa-mir-21 RECK Osteosarcoma 20480266 MicroRNA-21 is involved in osteosarcoma cell invasion and migration. 1083 hsa-mir-21 PDCD4 Carcinoma, Squamous Cell 20831814 Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma. 1084 hsa-mir-203 BIRC5 Carcinoma, Hepatocellular 22886454 miR-203 inhibits proliferation of HCC cells by targeting surviving. 1085 hsa-let-7a-1 KRAS Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 1086 hsa-let-7a-2 KRAS Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 1087 hsa-let-7a-3 KRAS Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 1088 hsa-let-7b KRAS Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 1089 hsa-let-7d KRAS Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 1090 hsa-let-7g KRAS Carcinoma, Non-Small-Cell Lung 18922928 A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. 1091 hsa-let-7a HMGA2 Stomach Neoplasms 18413822 Clinical significance of high mobility group A2 in human gastric cancer and its relationship to let-7 microRNA family. 1092 hsa-mir-34a BCL2 Neuroblastoma 18505919 A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene. 1093 hsa-mir-34a MYCN Neuroblastoma 18505919 A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene. 1094 hsa-mir-372 LATS2 Testicular Neoplasms 16564011 A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. 1095 hsa-mir-373 LATS2 Testicular Neoplasms 16564011 A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. 1096 hsa-let-7c HMGA2 Leiomyoma 17243163 HMGA2 was identified as one of target genes of the let-7 family of miRNAs and has been found to be suppressed by let-7 in vitro. 1097 hsa-mir-125b BMPR1B Breast Neoplasms 19738052 A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis. 1098 hsa-mir-128 NTRK3 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 1099 hsa-mir-485 NTRK3 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 1100 hsa-mir-509 NTRK3 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 1101 hsa-mir-765 NTRK3 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 1102 hsa-mir-148a NTRK3 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 1103 hsa-mir-148b NTRK3 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 1104 hsa-mir-152 NTRK3 Anxiety Disorders 19370765 Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disorders. 1105 hsa-mir-146a CFH Alzheimer Disease 18801740 An NF-kB-sensitive microRNA-146a-mediated inflammatory circuit in Alzheimer's disease and in stressed human brain cells. 1106 hsa-mir-17 BIM Neuroblastoma 18493594 Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM 1107 hsa-mir-17 p21 Neuroblastoma 18493594 Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM 1108 hsa-mir-127 BLIMP1 Burkitt Lymphoma 19530237 B cell differentiation in EBV-positive Burkitt Lymphoma is impaired at post-transcriptional level by miRNA altered expression. 1109 hsa-mir-127 XBP1 Burkitt Lymphoma 19530237 B cell differentiation in EBV-positive Burkitt Lymphoma is impaired at post-transcriptional level by miRNA altered expression. 1110 hsa-mir-182 FOXO1 Breast Neoplasms 19574223 Coordinate Regulation of FOXO1 by miR-27a, miR-96, and miR-182 in Breast Cancer Cells. 1111 hsa-mir-27a FOXO1 Breast Neoplasms 19574223 Coordinate Regulation of FOXO1 by miR-27a, miR-96, and miR-182 in Breast Cancer Cells. 1112 hsa-mir-96 FOXO1 Breast Neoplasms 19574223 Coordinate Regulation of FOXO1 by miR-27a, miR-96, and miR-182 in Breast Cancer Cells. 1113 hsa-mir-221 p27 Glioma 19424584 Co-suppression of miR-221/222 cluster suppresses human glioma cell growth by targeting p27kip1 in vitro and in vivo. 1114 hsa-mir-222 p27 Glioma 19424584 Co-suppression of miR-221/222 cluster suppresses human glioma cell growth by targeting p27kip1 in vitro and in vivo. 1115 hsa-mir-122 CCNG1 Carcinoma, Hepatocellular 17616664 Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. 1116 hsa-mir-106a E2F1 Colon Neoplasms 18521848 Deregulated expression of miR-106a predicts survival in human colon cancer patients. 1117 hsa-mir-17 E2F1 Colon Neoplasms 18521848 Deregulated expression of miR-106a predicts survival in human colon cancer patients. 1118 hsa-mir-143 ERK5 Lymphoma, B-Cell 17892514 Downregulation of microRNAs-143 and -145 in B-cell malignancies. 1119 hsa-mir-143 ERK5 Lymphoma, B-Cell 17892514 Downregulation of microRNAs-143 and -145 in B-cell malignancies. 1120 hsa-mir-1-1 HCN4 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 1121 hsa-mir-1-2 HCN4 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 1122 hsa-mir-133a-1 HCN2 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 1123 hsa-mir-133a-2 HCN2 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 1124 hsa-mir-133a-1 HCN4 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 1125 hsa-mir-133a-2 HCN4 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 1126 hsa-mir-133b HCN2 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 1127 hsa-mir-133b HCN4 Hypertrophy 18458081 Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. 1128 hsa-mir-10b PPARa Fatty Liver, Non-Alcoholic 19780876 Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-alpha expression, a novel mechanism for the pathogenesis of NAFLD 1129 hsa-mir-510 HTR3E Irritable Bowel Syndrome 18614545 First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor type 3E gene with diarrhea predominant irritable bowel syndrome. 1130 hsa-let-7a-1 ITGB3 Melanoma 18679415 Integrin beta(3) expression is regulated by let-7a miRNA in malignant melanoma. 1131 hsa-let-7a-2 ITGB3 Melanoma 18679415 Integrin beta(3) expression is regulated by let-7a miRNA in malignant melanoma. 1132 hsa-let-7a-3 ITGB3 Melanoma 18679415 Integrin beta(3) expression is regulated by let-7a miRNA in malignant melanoma. 1133 hsa-mir-145 IRS1 Colon Neoplasms 17827156 Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. 1134 hsa-mir-210 BCL2L2 Lung Neoplasms 19654003 low expression, targets pro-survival molecules MCL-1 and BCL2L2 1135 hsa-mir-210 MCL1 Lung Neoplasms 19654003 low expression, targets pro-survival molecules MCL-1 and BCL2L2 1136 hsa-mir-21 RECK Glioma 18591254 MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. 1137 hsa-mir-21 TIMP3 Glioma 18591254 MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. 1138 hsa-let-7b CCND1 Melanoma 18379589 MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. 1139 hsa-mir-1-1 MET Rhabdomyosarcoma 19710019 MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development. 1140 hsa-mir-1-2 MET Rhabdomyosarcoma 19710019 MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development. 1141 hsa-mir-206 MET Rhabdomyosarcoma 19710019 MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development. 1142 hsa-mir-125a ELAVL1 Breast Neoplasms 19875930 MicroRNA-125a represses cell growth by targeting HuR in breast cancer 1143 hsa-mir-128 E2F3a Glioma 18810376 MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. 1144 hsa-mir-215 CDKN1A/p21 Glioma 18810376 MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. 1145 hsa-mir-143 DNMT3A Colorectal Neoplasms 19638978 MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. 1146 hsa-mir-145 BNIP3 Prostatic Neoplasms 20332243 MicroRNA145 targets BNIP3 and suppresses prostate cancer progression. 1147 hsa-mir-15b CCNE1 Glioma 19135980 MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells. 1148 hsa-mir-21 MARCKS Prostatic Neoplasms 19302977 MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells. 1149 hsa-mir-21 HNRPK Glioblastoma 18829576 MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. 1150 hsa-mir-21 p63 Glioblastoma 18829576 MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. 1151 hsa-mir-21 TGFB Glioblastoma 18829576 MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. 1152 hsa-mir-21 LRRFIP1 Glioblastoma 19559015 MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme. 1153 hsa-mir-21 LRRFIP1 Glioblastoma 19559015 MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme. 1154 hsa-mir-222 MMP1 Carcinoma, Squamous Cell 19487542 MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1(MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cellcarcinoma cell lines. 1155 hsa-mir-222 SOD2 Carcinoma, Squamous Cell 19487542 MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1(MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cellcarcinoma cell lines. 1156 hsa-mir-29a DNMT3A Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 1157 hsa-mir-29a DNMT3B Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 1158 hsa-mir-29b DNMT3A Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 1159 hsa-mir-29b DNMT3B Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 1160 hsa-mir-29c DNMT3A Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 1161 hsa-mir-29c DNMT3B Lung Neoplasms 17890317 MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 1162 hsa-mir-34a MET Glioblastoma 19773441 MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes 1163 hsa-mir-34a NOTCH1 Glioblastoma 19773441 MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes 1164 hsa-mir-34a NOTCH1 Glioblastoma 19773441 MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes 1165 hsa-mir-34a CDK6 Glioblastoma 19773441 MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes 1166 hsa-mir-122 BCL2L2 Carcinoma, Hepatocellular 18692484 miR-122 targets an anti-apoptotic gene, Bcl-w, in human hepatocellular carcinoma cell lines. 1167 hsa-mir-15b BCL2 Stomach Neoplasms 18449891 miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. 1168 hsa-mir-16-1 BCL2 Stomach Neoplasms 18449891 miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. 1169 hsa-mir-16-2 BCL2 Stomach Neoplasms 18449891 miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. 1170 hsa-mir-206 ESR1 Breast Neoplasms 18593897 miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer. 1171 hsa-mir-22 ESR1 Breast Neoplasms 19414598 miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA. 1172 hsa-mir-221 CDKN1B Prostatic Neoplasms 17569667 miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1. 1173 hsa-mir-222 CDKN1B Prostatic Neoplasms 17569667 miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1. 1174 hsa-mir-34b CREB Leukemia, Myeloid, Acute 19258499 miR-34b targets cyclic AMP-responsive element binding protein in acute myeloid leukemia. 1175 hsa-mir-449a HDAC1 Prostatic Neoplasms 19252524 miR-449a targets HDAC-1 and induces growth arrest in prostate cancer. 1176 hsa-mir-224 API5 Carcinoma, Hepatocellular 18319255 Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target. 1177 hsa-mir-143 KRAS Colorectal Neoplasms 19137007 miR-143 directly recognize the 3'-untranslated region of KRAS transcripts 1178 hsa-mir-189 SLITRK1 Tourette Syndrome 16224024 Sequence variants in SLITRK1 are associated with Tourette's syndrome. 1179 hsa-mir-206 ESR1 Breast Neoplasms 17312270 The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines. 1180 hsa-mir-15a CCND1 Prostatic Neoplasms 18931683 The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. 1181 hsa-mir-15a WNT3A Prostatic Neoplasms 18931683 The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. 1182 hsa-mir-16-1 CCND1 Prostatic Neoplasms 18931683 The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. 1183 hsa-mir-16-1 WNT3A Prostatic Neoplasms 18931683 The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. 1184 hsa-mir-18a KRAS Carcinoma, Squamous Cell 19372139 The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras 1185 hsa-mir-200a ZEB1 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 1186 hsa-mir-200b ZEB1 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 1187 hsa-mir-200c ZEB1 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 1188 hsa-mir-429 ZEB1 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 1189 hsa-mir-141 ZEB1 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 1190 hsa-mir-205 ZEB1 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 1191 hsa-mir-200a SIP1 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 1192 hsa-mir-200b SIP1 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 1193 hsa-mir-200c SIP1 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 1194 hsa-mir-429 SIP1 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 1195 hsa-mir-141 SIP1 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 1196 hsa-mir-205 SIP1 Breast Neoplasms 18376396 The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. 1197 hsa-mir-34a MYCN Neuroblastoma 18504438 The MYCN oncogene is a direct target of miR-34a. 1198 hsa-mir-126 PIK3R2 Colon Neoplasms 18663744 The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers. 1199 hsa-mir-27a MYT1 Breast Neoplasms 18006846 The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. 1200 hsa-mir-27a ZBTB10 Breast Neoplasms 18006846 The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. 1201 hsa-mir-16-1 CCND1 Lymphoma, Mantle-Cell 18483394 Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma. 1202 hsa-mir-155 TP53INP1 Pancreatic Neoplasms 17911264 Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development. 1203 hsa-mir-16-1 CAPRIN1 Breast Neoplasms 19250063 Two new miR-16 targets: Caprin-1 and HMGA1, proteins implicated in cell proliferation 1204 hsa-mir-16-1 HMGA1 Breast Neoplasms 19250063 Two new miR-16 targets: Caprin-1 and HMGA1, proteins implicated in cell proliferation 1205 hsa-mir-16-2 CAPRIN1 Breast Neoplasms 19250063 Two new miR-16 targets: Caprin-1 and HMGA1, proteins implicated in cell proliferation 1206 hsa-mir-16-2 HMGA1 Breast Neoplasms 19250063 Two new miR-16 targets: Caprin-1 and HMGA1, proteins implicated in cell proliferation 1207 hsa-mir-433 FGF20 Parkinson Disease 18252210 Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein.