smORFunction

Introduction

smORFunction is a tool for small open reading frame (smORF) and microprotein function prediction. We collected 617,462 unique smORFs from previous studies for searching. By re-annotating microarray probes to smORFs, we estimated smORF expressions for 173 datasets in GEO. Functions can further be predicted by co-expression genes of smORF. In this tool, we provide function predictions for 526,443 of these smORFs in at most 265 models, 48 tissues/cells, 82 diseases (and normal).

Please cite

Ji X, Cui C, Cui Q. smORFunction: a tool for predicting functions of small open reading frames and microproteins. BMC Bioinformatics. 2020 Oct 14;21(1):455. PMID: 33054771

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Quick Start

1. Search a smORF by sequence (amino acid/nucleotide, exact/BLASTn/BLASTp/BLASTx/tBLASTn/tBLASTx) or by coordinate (hg19/hg38).
2. In Predict page, input the internal ID of smORF your searched and click 'confirm'. Or just click 'predict' on the right of search result table.
3. Choose tissue and disease of interest, click 'predict'.
4. For more detailed tutorial, please click Help.

Contact us

Dr. Qinghua Cui, 38 Xueyuan Rd, Department of Biomedical Informatics, Peking University Health Science Center, Beijing 100191, China
Email: cuiqinghua@hsc.pku.edu.cn
Homepage:http://www.cuilab.cn/